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        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
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        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
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            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
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        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
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        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
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            <begin position="566"/>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
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        <source>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11362.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="693" mass="76806" checksum="5FFD52B75121CA43" modified="2023-09-13" version="1">MDGDLITAAASSVGSNIFAILSIVTIALLALLVIRHYLPLRSTPGYLLVPVFLALALPCSIILLVPIDLASAAGDEETRTRGVWLPERVNLVAWRITYWLTFMLTWFILPLLGEYCDSGYRETRSRVIYSLRANARYQLIVLGTAVAGLVYFIWENGLHVASIKGLVMALAYAWGLVLGLALMGHGLVALPRRLYRNANVSERLRQLQSQAPKFNDGLEEATDKLDELERTVVQLKRHKGGASSAQQEWIDELADTSTLPELRPGMTAAIQATNPSIPAVVTDRYLADLTRKLKRARHRKARFQDEWSNLCQQAQDTQTILDSALSKKLDFGRKQSGEGGILGKLVVLTPTMRYYLHASIIPYLRIGVAGILGVASILIVWSELVKSLAPSLSVIGLTVVHGNKVNFGGQLIAAAWLLYMDTTALYAISDVKVWGNRALVKRQTYAESATWYSLQVAKLTVPLSYNFITMMPPAVYKETMFFRFLGQLINLTPLGQGFSAFFPCFLVIPVLATLFNLYGKTKSWFGFGVLEDDSEDNPSGFGTGGWREGKALIDRELQSRGSGANLGLASRGASLDQERGTAGASAPPRRVAEDQRGREQYRDEGIREANRQFNAITNQEEDDQGDSARHFYQDFGERVRNTFDTVDQPEWIRNIGSACKAPKWMQNDSRDENGGSALSKWFGGRAEDGRVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6I5</accession>
    <name>A0A9Q8L6I5_PASFU</name>
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        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="5" type="ORF">CLAFUR5_00827</name>
    </gene>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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            <end position="237"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="384" mass="42866" checksum="F7DEE317179C7CF1" modified="2023-09-13" version="1">MQSLPPYPYTNYPEHNPGHLSPQATYPMPSEPPENMQTPVSPVSAQSPHDPTMADQQLHVSRKRSHSEMSQSDTLTNAILQQSQPQTQTQTQPHSRSGSVASQLGASPNGANEDFAPRGSRAFKRGDPPMNDQKKYICNFAEECAGQTFDRKCEWSKHMDKHDRPYRCGHASCAKLQGFTYSGGLLRHEREVHGKHGGPKAALMCPVRDCKRHSGKGFTRKENLNEHMRRVHPDVDAASQPSQPMLLKRDATDITIGTEDGDTPASIGGISETIDQQQDHYAAPPAASNKRKRSLAGEFQIDFTPDHELELKRLRQLVQDQEERIRLGDERIKLQDANAIHYENRIQELEGQAADQAERISRMESELAEANIRSQLASANSAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6N0</accession>
    <name>A0A9Q8L6N0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldolase vrtJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900098.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71980828"/>
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    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="5">
        <location>
            <begin position="75"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="45419" checksum="F91462BF505094DB" modified="2023-09-13" version="1">MLSRSALLQRISRSSFSCPLPYLPSPPLSPYHHTQSSIHTTSSTMASGISAQRIEAEAQHLANGTSTSINAWASPSPSAFDFRTATTLADDVFQEDPTTNNLETFMAKLTGKEAGLFVMSGTMGNQIAIRTHLQGPPHSVVADHRAHIIEWEAGGVASLSGALIKGAVPSAGRSYVTLEDVKKVTDLRDDVHGCPTKLISLENTLGGTIMPLEETRRISEWARENGIVMHLDGARLWEAVAAQAGTLKEFCDCFDSVSLCFSKGLGAPIGSVIVGTKAFVKRSRWVRKAIGGGTRQLGVLTAAARVAVEDTFLGGKLNECHERARQIEKIWSKYGGKTTNPVETNMVWFDIEAANITAKDFIEAGQRVGLRLLGGRLVVHYQIGDEALERVDMLAQAVLKGKQLNGSVVHDVERMQITTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Q9</accession>
    <name>A0A9Q8L6Q9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756241.1">
        <property type="nucleotide sequence ID" value="XM_047900028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Q9"/>
    <dbReference type="GeneID" id="71980758"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00880"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000010">
        <property type="entry name" value="Glutathione peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="33"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="215" mass="23848" checksum="C2B9FD3101F36811" modified="2023-09-13" version="1">MQVPRFVFCQTGATHTTRLGSAYPVSRRHFTNMASATTFYDFKPNNKGGKPYDLSNLKGKVVLVVNTASKCGFTPQFEGLEKLYKEVKATHPNDFEILGFPCNQFGNQDPGNDDEIQNFCQVNYGVSFPVLGKTDVNGADANPLWEWMKKEKPGIMGLQRVKWNFEKFLIGRDGKVKQRWASTTAPDKLKSTIEAELKASPGASKTAAEKPTATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6T4</accession>
    <name>A0A9Q8L6T4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA ligase sidI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756271.1">
        <property type="nucleotide sequence ID" value="XM_047900742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6T4"/>
    <dbReference type="GeneID" id="71981472"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01594"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
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        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
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    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF6">
        <property type="entry name" value="ACYL COA SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
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    </dbReference>
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        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="43703" checksum="78715DACCCCDAF62" modified="2023-09-13" version="1">MGVRKGDVVGVMAGNCQEHIDIFSSAARIGAPVASMHATFTLDELCGALASSTCKVLFIATKIGKRDTSALIEMAGRLCNEDSNLEHVITIGEPQLWSETTNYQVWQTFLQRSESVFIDEALLIHFAQLVSPTEPISLQFTSGTMGNPKLATLTHFNILNNALFMGNAMDLCSRDVLCCPAPLSHCSGLVVGFLNALVHGTMLVLPSQVFEAERTVDALVQERCTAIIGVPTMYLAELEVLKTRSLDKAFLRTGLIAGANVAPALMERIYAELGAEAMLIAYGMTETGPITFCFMDNEGYCYVSGRLKDIIIRGGQNIYPAEIEERLLQLPTIAEAVVVEIREWIRETLGRHKAPKHIFWVGVGKGLASIPKTGSGKPAKHELRKIALELLQDINVGQARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7D5</accession>
    <name>A0A9Q8L7D5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine nucleoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756579.1">
        <property type="nucleotide sequence ID" value="XM_047901416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7D5"/>
    <dbReference type="GeneID" id="71982146"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02268"/>
    <dbReference type="OrthoDB" id="2331083at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009486">
        <property type="entry name" value="Pur_nuclsid_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643:SF1">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06516">
        <property type="entry name" value="NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040483391" evidence="1">
        <location>
            <begin position="21"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="41701" checksum="609A2F091F597D52" modified="2023-09-13" version="1">MVAITHTIVALGAWLNLAAATISRLEAAHIPRTLEYVVKPKVVIISMFTPEAEVWYGIEEFNLLGLNITVPGLSPLFPNVHCTADGDVCQVITGEGEINAATTIASFVRSPRFDLTTSYFMIAGIAGVNPEVATICSVTFARYAVQVALQYEFDIHEYPQDIYGTEVFEVNQNLQHLAASFARTATLNDSSNAIAYRAHYAASPAYTAATLGPSIIECDGATSDVYYSGSLLSSAFSNYTTLLTNGSGTYCTTSQEDSATLEALTRAAVDNVVDFSRIIIMRTVSDFDRPYPGEAATTNLFYAEQGAFEPAVKKLYLAGVKVIEGILEGWNGTFKRGVEAGNYVGDIFGTLGGMPDFGPYARERKQVLTKRSAKARRGGVKIRHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Q1</accession>
    <name>A0A9Q8L7Q1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Threonine dehydratase</fullName>
            <ecNumber evidence="14">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_01797</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="14"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756706.1">
        <property type="nucleotide sequence ID" value="XM_047900945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Q1"/>
    <dbReference type="GeneID" id="71981675"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01797"/>
    <dbReference type="OMA" id="TRFEYTK"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1020.10:FF:000001">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000008">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000005">
        <property type="entry name" value="Threonine dehydratase catabolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="16">
        <location>
            <begin position="399"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="16">
        <location>
            <begin position="495"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO12340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="62636" checksum="132F0FE187060DE9" modified="2023-09-13" version="1">MATEQDSETSNGTATPETNGTHTPTTPKPKHTALALTEYSANPSPPPKTPNEKPLHAGVPGHLLLPNGHPDYIRLITTAKVYDVVEQTQLSHAVNLSNRLETTVMLKREDLLPVFSFKLRGAYNKMAHLSQQERWKGVIACSAGNHAQGVAFSARKLQIPATIIMPLGTPAIKHQNVSRLGGNVVLHGADFDEAKAECNRRAVANGLTIIPPFDEPYVIAGQGTIGAEIIRQADLDKLEAIFCCVGGGGLIAGTGAYIKRFAPHVKIIGVETYDANALVQSLKLGKRVTLPEVGLFADGAAVKTVGEETFRICQDVVDHVIQVDTDDICAAIKDVFEDTRSILEPAGALSLAGLKKYVAANPSSDTRRQLVAVASGANMNFDRLRFVAERAAIGERKEALLSVTIPERPGSFAKLVETVNSMVVTEFCYRYATESAANVLIGIQCSATTRTRDVQDLIQRLEKEGMAARDISADELAKGHIRYLVGGRSNAEHERLFAFEFPERGGALYKFLTTLQPGYNISLFHYRNYGGDIGKVLAGIQCPPGEESGLEQFLRELGYGYTEETDNETYKMFMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L859</accession>
    <name>A0A9Q8L859_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_00052</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757003.1">
        <property type="nucleotide sequence ID" value="XM_047899200.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71979930"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00052"/>
    <dbReference type="OMA" id="AEPLSQF"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1535"/>
            <end position="1890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="743"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1226"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1336"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="795"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1146"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1344"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1890" mass="207302" checksum="F15C8948A7B9AD51" modified="2023-09-13" version="1">MPPSQRVTRSAAARLSADGDSISNQQQSPTTTAAGSPPASTTTSSSSTKRKRKAAPQPSPPATERKTKRPRGSNAAATNPDADQEQPEPVEAPKRGKKRAASAAMSSAGSAGPSQKNCERKTDMDRPSSDNTSAETSPQQAPRDSSRRKSSRRKSKEDPTASTSGASSRKSRKGSRKDQDVVMKDVDEKGKEPKEDADDDEEQSRQDAGTGAEGSEEPSRRQIQDEIDAMERGEDPFATGYLSRFAGHHGLSSSLRALSGIVSGTNSRLRGLLERLRAKDDPSMQLIALQDLSELLLVSNEDNLAGHFAPDQYVKELVTLMQPNDFTGEENPEVMLLACRCIANMMEALPAATASVVYGRAVPILCQKLLEIHYIDLAEQALSTLEKISVEFPSSIVREGGLTACLTYLDFFATGTQRTAVTTAANCCRNIPEDSFPTVRDVMPILLGTLSSSDQRVVEQASLCVARIIDSFKYHEGKLEELISPELLRAILRLLLPGSTNMIGPNIHTQFLRVLSITARASPRLSVELFKMNVVDTLYQILTGVSPPAGTDGVAAKIDKNVIMQSIIRTPREQIFETLNVVCELLPTVSPENLTFLDDLQDAGYTGSESVSMSTRSKTSPNDKRVELLKECTEEVKRFAVILFPTLMHAYTSTVNLSVRQKVLTAQLKMLSNLETGILEEALQGVTYASHLAGILTQQENSSLVTYALQAAELLLKRLELVYRPQFYREGVIAEVTKLADRPMAPGPTPADLSQPAPDLLPPPPPEVDEQPGDIDQDEEDDEQQAIEVDVAGEATDEDDNAQDENEPHEDNENDEDDEDDEDREAQRVHSDDSELPPTRHRRIPNLQDIITLRSKRFMEAHGDEGSEEMRSKATKVLDDIKSVSSKLQSCYNSADKQGGLSLYRQLARYFRGDALEGITSYELLTSGIVDTLLELFASEDEDVSQSAQADFLEAFMGTSIDTNLATGASESPSTAFSILIYKLQELLSRAEHFEVITVHHNAFESNRGSAASMLAKQLRLKLVAGEESGIPRAYRNIMVSIHAIATFKALDDYLRPRISLSERPRGARREGGISSAMAAYAAAMAGRGDRSAPPIPSLPSLGRSLPARPSNKLPPRTKSSKSDSNGEASKPEDAAARSLRRSTRRQSGQPSAAPDAEPDAPTEDKNDLQEALEAADEAHISDEDDDDDVDADLDALVDDLEEGGLEQDVADPGAVNIEAAGTGKVTARTEDGARVSTPTAQGVPTPTGRDRMSAIARLAAAREMLSTPTSSRPGMSYASALQATPQDWHIEFSVNGQPISSETTIYRACHFNQAQGDELSARNIWSATHSISFKRVSGPPPADRATPTVTTTASSSTDLPPSLDNHPVTSSILRLMSILHELNANPDDVVHDAKSAVKLNAEPQSQFVNTKLTAKLNRQLEEPLIVASQCLPSWSEDLARLYPFLFPFETRHLFLQSTSFGYSRLMSRWQSSQSESESRRHRDDRPFLGRMQRQKVRISRGRILESALKVMELYGSSSSMLEVEYFEEVGTGLGPTLEFYSTVSKEFSKKKTKLWRENESFENDEFAFGKRGLFPAPMNEETSRNENGQRVLHLFKMLGKFVARSMLDSRIIDISFNPTFFRIGDSTAVAPSLGAVATVDEDLAKSLKMLKKYATTKQRIDEDIQLSAAQKLQKTQQIRVNDAKVEDLGLGFTLPGYPDIELLPHGSTIDVTIDNVDLYIKKVIDFTLGAGIEKQVEAFRAGFSQVFPYSATKAFTPDELVMLFGRVDEDWSLETLMDSIKADHGFNLDSKSVRNLLQFMSELPAPTRRDFLQFITGSPKLPIGGFKALTPMFTVVCKPSEPPYTSDDYLPSVMTCVNYLKMPDYSSLDILKEKLNVAIKEGQGAFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L992</accession>
    <name>A0A9Q8L992_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tripeptidyl-peptidase sed1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757525.1">
        <property type="nucleotide sequence ID" value="XM_047903014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L992"/>
    <dbReference type="GeneID" id="71983744"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03866"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="34162" checksum="8AC5806200F1A109" modified="2023-09-13" version="1">MIYPQIIRQLQVGGPNFLDWYGDGPFNRVLTSLDEQYCDKSYIPPCTHEVCDGDPTEQSDTGGAHCGGVPKTNVISISYGEMEAYLLPKYQKRQCSEWMKLALQGTSVVFSSGDSGVAADPGFCLSADGTPSIYGNVFAPSFPANCPWATTVGATTLKGDSLDDGERAITGFQSGGGFSNVFHQPEYQKTAVDPYLQNHAPAYWKDTYNRTGRGYPDVSAVGFNIATILLGKLVPAEGTSASAPIFASLLNLINEERLRANKTAVGFVNPVIYKHPEMFNDITEGSNPGCGTNGFPATEGLGTPTYEKMKEVFMSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9B4</accession>
    <name>A0A9Q8L9B4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757676.1">
        <property type="nucleotide sequence ID" value="XM_047902633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9B4"/>
    <dbReference type="GeneID" id="71983363"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03485"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="444"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="979" mass="108606" checksum="B8EAA880CA6B413F" modified="2023-09-13" version="1">MALPQTTFVPCPNGTGLMPHPLALDSISQAQCRVYQQDRPVVEGAFRQNTITFSMRQIMLSHLSFYCYRGVLNGAPCTLSEGQLTNMGTWLLQQYPALSMEEQVTWLRADLQVRESISTKDQQILKLDNIAQAHRGNSATTEPATEYILAIQRRLQITLPQIDHLRKCEERVIALIASRQLVKPLPIVEPVSQTPAKSVPERTPLASLSANMASKAQTMPGTSLKRKRADAEPRNASEVIELLDDSEDEDQLQGKIEAIQAKIAAMRSRTSKEDEIIPGKRVRKSRKVAGETKTKPVVQQGPILANAQISPRPTPVTRDAYAPPRSSQRSPPSRSSSGSVKSSQPREAISMAAKSSAAGRALPTSSVFSPQNQRSLPASSRPCFGLVAAGQATAPVPMSNLCQIAQPPSSQAGRQQHVVDLTSSSPVRAQPASSMPASPDGPTLCKEQQEVVNLIMAGNNVFYTGGAGCGKSTVLKAFVPRLRDRGKVVRIVAPTGRAALDINGSTTWTYAGWTPLHMKKPLADLRKAAHGKFVRNRLKGTDVLVIDEISMVENHMLSRLDAIMKEARGNNNAFGGVQLVVTGDFCQLPPVRPFQYCMHCGREQAQKILADGRTVHRCYQHGDSNDDDKWAFRSTVWQDCNFKHINLTNIHRQSDEVFIKILQKLRIGTELTTADRKLLIDHPCDVNNAVKLFPTREEVRRINMAEFDKLKTAKHSFTCLDHFRWNEEKHPHRRTKGDRDHRDGSLVALREHRLDSLVEYKQGMLVVLLVNLDIANGLVNGSQGRVIGFEPFDPAKLPKAGRDVGGTRTGKAPSGRFGTSQGGGRRARERSMEPEQDSKGELRGEYAFFREAQISEYIQHARNISKLWPIVEFENGLKRTIYADCQVNELGDEKEYTLLARTQIPLIAAWAMTIHKSQGMTLNRVIVDLDKSFEEGQEYVTLSRARSLDGLKVMSLGDNVGKGGNAQVKEFLWQKFKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9L1</accession>
    <name>A0A9Q8L9L1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757681.1">
        <property type="nucleotide sequence ID" value="XM_047902848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9L1"/>
    <dbReference type="GeneID" id="71983578"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03700"/>
    <dbReference type="OrthoDB" id="7772923at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="177"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="397" mass="45223" checksum="BA8A7F2CA304DBD0" modified="2023-09-13" version="1">MPVTKLPFHADHIGSLIRPATVSEAQEKADAGQISQEELREVQRKEIADIVKKQQDHNVRALCSGEFDRKYYFSGFFEKLDGFKEVSPVPWDLARLSAAPIAALKKAGKQYPMAAICEGKIKYSKSPYLDNWKLLRHQLPQEQWGQAKFTMPPPCYFHLRLVPGKCYPKEVYATEAEFFDDLAAAYRQEFKTLYNEGLRNIQIDDPTLAYFCSDDMLKGLREDGEDTEKLFDLYLKAHNDCIADRPDDLHVGLHICRGNFSKSMHFSEGSYEKIAERFFKTLNYDTFYLEYDNPRSGGFEPLRFLPKHKNVVLGVVTTKDPQLEDQNLIKSRVQEAAQIIAKGQGRSVEEAMENIGISPQCGFASVAIGADGMTEEKMFAKLKLVQDVAKDLWPDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA44</accession>
    <name>A0A9Q8LA44_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alcohol O-acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.84</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alcohol O-acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03652</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aliphatic alcohol + acetyl-CoA = an acetyl ester + CoA</text>
            <dbReference type="Rhea" id="RHEA:17229"/>
            <dbReference type="ChEBI" id="CHEBI:2571"/>
            <dbReference type="ChEBI" id="CHEBI:47622"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.84" evidence="6"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757937.1">
        <property type="nucleotide sequence ID" value="XM_047902800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA44"/>
    <dbReference type="GeneID" id="71983530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03652"/>
    <dbReference type="OMA" id="MMTTSWG"/>
    <dbReference type="OrthoDB" id="5954035at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008126">
        <property type="term" value="F:acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004026">
        <property type="term" value="F:alcohol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051792">
        <property type="term" value="P:medium-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000137">
        <property type="entry name" value="EEB1p Acyl-coenzymeA:ethanol O-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="10">
        <location>
            <begin position="148"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00080774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="51663" checksum="00068AE91449E1D3" modified="2023-09-13" version="1">MAFSWYPGKQDITYTHSPQPLVLPTKTGPKRAFPEIVKDITPECYLNPFLFNGHLQTAYTAVKMAGPAIHYKRRVVEQEDKDFPGHFTIDIVTAPPPKSNAEAQDGGLDDQGLREDPMGVGHHRLPPRTTYFTDKEFENLGSDDTKPMLISLHGLSGGSYENYLRQVLEPLVKSTPEGEEAGGISSGEWEALVVNSRGCAGSKITTSMLYNARATWDVRQVVKWVRKTWPNRKVYGIGYSLGANILTNYLGEEGDKCLLSAAVIVSNPWKLEAGSLSLQRSYIGLEVYSKTMGKSMLALFDTHKEQILKNKNISYEGMHKLKYLHEFDRAVQCATWGYPTEGAYYRDASSADSVMAIRIPTLCVHAKDDPIAVDEGVPYEEIKQNPYVVMLATSGGGHLSWFQLGGARWHSKPIVGFFNAMAREVDFDQVEKPELAAQGPHGGIQTPFAFNPVRRSLHIADSPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAR4</accession>
    <name>A0A9Q8LAR4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="23">Ceramide very long chain fatty acid hydroxylase SCS7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">CLAFUR5_03021</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="23" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="18">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758411.1">
        <property type="nucleotide sequence ID" value="XM_047902169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAR4"/>
    <dbReference type="GeneID" id="71982899"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03021"/>
    <dbReference type="OMA" id="WTIIEYV"/>
    <dbReference type="OrthoDB" id="2204368at2759"/>
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        <property type="component" value="Chromosome 2"/>
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        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:fatty acid 2-hydroxylase activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:heme binding"/>
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        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
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    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 19" id="KW-0349">Heme</keyword>
    <keyword evidence="14 19" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 18" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="22">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="19">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="19">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="296"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
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        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="356"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>Zn(2+)</name>
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        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>Zn(2+)</name>
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        <location>
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        </location>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005747"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        </source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14045.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="410" mass="46932" checksum="BA66E32F87F3DDAD" modified="2023-09-13" version="1">MPGRTLPTLPSAEVAAHNTSKSCYVTVGTKVYDITPFLEDHPGGGDLIVEYGGKDVKEIMQDEVSHAHSESAWEILDDHLIGFVATDKVLEAVKEGNDPFAVLLMEPTSKGMKDLEQAGNGAAAEVKARDQVVANGEGEHKPVFESTGMSSEEDLNKETDPSSDYKKHKFLDLNKPLLMQVFLGNFSKKFYLEQVHRPRHYKGGDSAPLFGNFLEPLSKTPWWIVPTVWWPPVAYGTFLCAQYFSFPILAAYWITGLCIWTIVEYGLHRCLFHLDDHLPDNRYAITLHFLLHGIHHYLPMDRLRLVMPPTLFIVLATPFWHLAHTVFFYDWYAAVAVYCGGIFGYTMYDMTHYFLHHKNLPAYYRELKKYHLQHHFMDYENGFGVTSRFWDRIFKTELPPPPTPKVLKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAR9</accession>
    <name>A0A9Q8LAR9_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_03417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="604" mass="68656" checksum="71228F6284712A77" modified="2023-09-13" version="1">MLGKRKHAASASASASASGPGVMMASVQKPLPAPDMGQAPSNAFTAKGIEREIPRYVSYTSPVSNFPPSDVSRSATLPLNLVALIVSYLDDIGDIARVTRTSRLLYYMTLPQLYEKVNLRSYADIRYVNGRPQGFGSGSPFQMALNGLVTKQHGALVKDFRIWGQWKELGIEDFAKGRVPDNSMMLTILLRAATDKMTRLQSFCWELDCKPLKTFYQGLGNHNTLTKFVLRFPSTRMPRPSVLIPPMTNLRMFHAMDIDPMCYPDDISMLMLHSKKLEDVRLHFSPRMRAEAESIMNLNMFFGRCHKAGYKLKLKHFGIHNFFGPNVLGMEQIFDLNVNCSVTFLDTFGGNDPRTIFVDDTWKNVPLDMYTNFKCVRANEVAPEPVQIMKNARTKMERMYVVNERRKPSGFTPEDRIQSPLTPNLDSPIDPRIRELGKEYLETLMHYHGNTLTHLLLSDQWALSADDLAALIQHCPNLVELGCAVNTSDHTMLELMLPFLPQLQAIRILTNEHSIEHLNSWSHEERMWRMGYELGQKPHINVKLIGIGNVQYKVGNLVQLMREDGTVEMRREMSMADKEEALKWEVWRLDCLDLSVDPVAPFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB58</accession>
    <name>A0A9Q8LB58_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_03539</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Involved in the replication of mitochondrial DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758637.1">
        <property type="nucleotide sequence ID" value="XM_047902687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB58"/>
    <dbReference type="GeneID" id="71983417"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03539"/>
    <dbReference type="OrthoDB" id="5588663at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005760">
        <property type="term" value="C:gamma DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08641">
        <property type="entry name" value="DNA_pol_gammaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000035">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.390:FF:000003">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.390:FF:000006">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
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        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047580">
        <property type="entry name" value="POLG_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
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    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="16">
        <location>
            <begin position="696"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1064"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="1075"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1087"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00057053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO14271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1167" mass="131559" checksum="E48A70975CDD43B2" modified="2023-09-13" version="1">MRSRCHRNVVHALERTQQTSLLRLRPQPLKKWSCAQKCYASTAVAADVATHHRPRLLAVSSEARHNEIGVQQVSAHIHPQLFPTATAPKPDAELVSLSKDHLARHELLGKTSDNALPIGFDLPTLHGASLDEHFYRLGMDSAEPFLSLSKKYARASPPPKPRQWVQRSGWTKYYEDGSSEAVAAPDADELTFDTEVMWHETSFPAMACAVSATHWYAWLSPWLLGESENDRHLIPLGDPNQPRIIIGHNISYDRARVAEEYSLEQSNNFFMDTMSLHVAVNGMCSRQRPTWMMHRKEREMQDKIAAADESVDLASLLDNRESFDEEEELWVGRSSVNSLRDVAKFHCGITIDKARREWFGELDRDGVVERLDELLDYCAADVEITHKVYKKVFPLFLETCPHPVSFAALRHMASEILPVNKSWEAYIANAEATYQKLSSGVTERLVDLADKALEHRTSSGVYEKDPWLCQLDWSGQEVRMVKGKKKGDPPRPAARQKKPGMPQWYRGLFARNDADIALTVRTRIAPILLRLAWDNNPLVWSDKYGWTFKVLHANAGKYHDQSMTMCNILEEEDFTLRDDLEHTYFKLPHKDGPDARCTSPLAKGYLKFFESGTLSSEYAYAKEALEMNASCSYWISARDRITSQMVVYENELPDAPSPESELGYILPQVIPMGTITRRAVENTWLTASNAKKDRVGSELKSIITAPPGYCFVGADVDSQELWIASLVGDASFKLHGGNAIGFMTLEGTKAAGTDLHSRTAKILGISRNDAKVFNYGRIYGAGLKFAQSLLRQFNPTLKEEDAKRIATNLYQETKGTSTTKKMLHERKFWRGGTESFVFNKLEEFAEQERPRTPVLGAGITQALMRRYISKGGFMTSRINWAIQSSGVDYLHLLIISMEYLCKRYNIDARLSLTVHDEIRYLAKNEDKYRCAMALQVANVWTRAMFSQQMGIDDLPQSCAYFSAVDIDHVLRKEVDMDCVTPSHPTAIPPGESLDILQILEKGDEAYLDPAEVPKTAPRPERFDYTYRQPVMEGLHNDNALPYLKAQIASTPAELNKIIKELKTPAPKNASPDDMGGNGSQGEGGALKLKRTSKTGGRKSKKSDDRNAGVPLRNVTQLAKLAPWAPEPVIHNRFTNWYDYTNKDHQLSRSWGNTAVDVGVPKRLPTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBA5</accession>
    <name>A0A9Q8LBA5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758460.1">
        <property type="nucleotide sequence ID" value="XM_047902707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBA5"/>
    <dbReference type="GeneID" id="71983437"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03559"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF165">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="31"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="327" mass="35908" checksum="D543730E1163D41A" modified="2023-09-13" version="1">MAQAVLYGDEVLVLIRSVVASRATSDRPSFSAIRWDCLWVMIAYALALVAQSFITVSYRYAVEKSEDAYEQLKSILYWSIIGTMFNIFSMAFGRLSVIALLLTLQGTTISLGWRRALQILGVLQLIISALQALVTILQCNPPRKAWDIAAPGSCPLAEETKQIGYASGAFGAFSDFALAIYPIVLIIGPQQQMKRSLKVAICVIMSGGVVAGVAGIATSALVKDVTYTGGYGTVLTWTLTQTWFIIIFGSLPTIRPVFVAFGETLRMLSARLKSRLVSHEATDRSSWIELEDQKQPGAQHRPDAWLDTHTTQTTINSSTERQDSVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBN6</accession>
    <name>A0A9Q8LBN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reductase pytE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758833.1">
        <property type="nucleotide sequence ID" value="XM_047902036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBN6"/>
    <dbReference type="GeneID" id="71982766"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02888"/>
    <dbReference type="OrthoDB" id="63935at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004074">
        <property type="term" value="F:biliverdin reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="35"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="284" mass="30703" checksum="09A5334A688B9006" modified="2023-09-13" version="1">MTTCTLDSQRHIHLYNDHNTNPTTSEKSKTLAFFGAGGDCAGYCLANSLKAGYTCRALARAPSKLLDSLKKKGVPQATIDTNLTIIQGDVKNLDNVKSTLHTASGLPVEVIISGIGGTPNFQVSLTQPLGMTEPNICNSAGSTILRAASEPHLQHTEHSKPLLVNISTTGIPAPGAPWDVPCALSPLYRWGLHVPHEDKAKLEEKLREEVRLSSCGIKGYVNIKPSLLFDGESKGLQAVKQGVDEKPAIGNSIHRQDVGLFIFEHFVKGEVVDEWINKSLTITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBN8</accession>
    <name>A0A9Q8LBN8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nonribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758800.1">
        <property type="nucleotide sequence ID" value="XM_047902996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBN8"/>
    <dbReference type="GeneID" id="71983726"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03848"/>
    <dbReference type="OrthoDB" id="3641063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="23048" checksum="4DBFC6F85377F005" modified="2023-09-13" version="1">MAQSPATQPSNEPVYITYTSGSTGHPKGVMIAQHAVTTGHQVHAMRMRINSSSRVLVLAAPAFDMAIENMFMTLFQGACMCVPSDTQKYSIDDLLDFAKTSRANWMSCTPSYLCLFRSEALYMMDAVLLGGEPIPRSIVESYTKCSSQGARIPTLMNGFGPSECALGCCILNEAISPQISDQCIGEGFRATTWIVNKDDVESLLPIGSTGELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCB5</accession>
    <name>A0A9Q8LCB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="10">dUTPase</shortName>
            <ecNumber evidence="10">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08004</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="2">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="10"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759130.1">
        <property type="nucleotide sequence ID" value="XM_047907152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCB5"/>
    <dbReference type="GeneID" id="71987882"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08004"/>
    <dbReference type="OMA" id="NTIHEPP"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.40.10:FF:000004">
        <property type="entry name" value="Deoxyuridine triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001862">
        <property type="entry name" value="PRK00601.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="12">
        <location>
            <begin position="99"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="247" mass="25553" checksum="D8BC61A5786B2367" modified="2023-09-13" version="1">MADQTPAPDHAAPSVPNSPLPKRTKYTEAAPSLTVASILNDQPPTPTPDSLPNPLSEMSTTTTNNATALPSMPSIPAMPPMSFEPPPPALQIKRLSPSAKLPTRGSEYAAGYDLYASKEAVVPARGKVLVDTDISIAVPAGTYGRVAPRSGLASKFSIDVGAGVIDADYRGPVKVLLFNLSDVDFEVKVGERVAQLIVERIYTPQVLEVQELETTVRGAGGFGSTGGFGGALPAMAAPAVPGTAPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD66</accession>
    <name>A0A9Q8LD66_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
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            <begin position="21"/>
            <end position="444"/>
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            <begin position="352"/>
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            <begin position="382"/>
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        </location>
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            <begin position="383"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="47723" checksum="81C0DF95FDB3EB78" modified="2023-09-13" version="1">MEWLQPLILLGTTLIALVQAQQSIPQSNNGSVLPIWGLATLVQGGSSPLCNKTFNDANGTGVFSFNPNVPQGPQQGQPENFSGRTQPVSIAVTLQNPGFNSTNSTSTAASYTLWYDTNGANYSDRYALGYDVCALVGFSLNYNTQLRGQSDNGSCLSTLDQPCISAIVSTVQQYATWLTTASPGPDSNLTTTSLPDVCRDLSHALVENFPKECSYFFQDKLDGLAYPLTSFGDQYQTGLTSNCTMNGTFQNTLSFYSNRSQSIYTAWADSVTPVIGVWMPVADAGAQTTITETVANVFCGHIDDINGRSYQPPDLPQPTPVAYNATTNTTNTNSTMTEDTETSDSSGLSGGAIAGIVIGVLTALVIVAGLIYWLMRRRRAQKKPQDVTAEKTTAELHGQDSRFELGGDDAKKELPAEERKAHARTVSELEAKTVQREPAELPAS</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04749">
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    </dbReference>
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            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
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            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26037" checksum="370391F26C15B8C3" modified="2023-09-13" version="1">MARCCLVFTSRRWVDGDPVSMPSPSHNHIPHHPLAQRPAISTTLSALIIQHNNKPSTTMSTAPGEWQKHFCACCCGGTCSSCLVIHFCPCYMHGKNYARLEEYPDVHHGHVKTFNGPCLVYCLTGTILGPLKFILTMMQRSDARDELNIRGNGCADCCVAFYCEPCAMAQMDTELNRRAPTTPVGALPYVSAVPYAQQPPEMVYAPQPSGVLAPPYGTAQAPQPLPAPQPVYQPMTHP</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
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            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="459" mass="51810" checksum="4CA7F63DE49E4B12" modified="2023-09-13" version="1">MAPSRKRKGNTTAGGNNKRAKNAKRSDRSSVTMPSSPMLRTSTSTEQLLPPKLGTLPIEILEQIVEDMSLEDQVHFASAAIEGGYIHIVDTLIAINVEVILIILRQIGGFPQLPAFANEPLTISGCLMTIEGRTNMDRPSATSLAQLGITDLTATYSTLFQAIGTDPAQVDATTVYHPRQAEHTQLRRLRANDELVRYCQDGGKGRILLWPLRLFVDIDALPQVDDICRKCFARSPFGTRHYPFLYCDECLETRFEGNELIRFADVDHFMAPVKKDPTPTFARALDHPWLCLIGNKNTRRMPGQPGPGPWITRDHLPFLFRMRCNANLPEGVIGPVIKLECLLPSRAMDNALIKRYDACMICINNAQEVIGTQERALPLPPWHPVGHPRRVQRTSRGRIGVHDMVRMRGMRRKEWFEAAFEAAATSYDWWHATKQRRAAWNRARWSSVTRMDIEAIGRP</sequence>
</entry>
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    <accession>A0A9Q8LGE2</accession>
    <name>A0A9Q8LGE2_PASFU</name>
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    <organism evidence="2 3">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGE2"/>
    <dbReference type="GeneID" id="71983985"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04107"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
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        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="13176" checksum="DDF05178EE8EE5C0" modified="2023-09-13" version="1">MPPTTTTAAIINGMKMAVVGLLAYYGQQRVQHATAAAASAALKKEKEEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKIRDEVEMLFVLGRGDLGRGEGEGEDESPSALVAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGF7</accession>
    <name>A0A9Q8LGF7_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LGF7"/>
    <dbReference type="GeneID" id="71985092"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05214"/>
    <dbReference type="OrthoDB" id="10652125at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="23775" checksum="1639D4B7D3F43EE8" modified="2023-09-13" version="1">MSQQPESEITAHEEDVHMLDAVAQYRDGRLVEATEEQDWLDEQNAPVLEYRDEDSDDAELLARIGYDHETGVLDIQNPSVYHGDESSDEELSHRNAEGSDFWRDVVPDEAQFSKRMPAQDWALKHEKAARLFAETGEGNSMLQQDGGGDALIINAQSNQHGRITGEDFAWSGAAGSTTEPAEEVHGALVRWVRLRGREFRLRNTCPWLNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGG5</accession>
    <name>A0A9Q8LGG5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Alpha-1,2-mannosyltransferase MNN23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04108</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNN1/MNT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761319.1">
        <property type="nucleotide sequence ID" value="XM_047903256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGG5"/>
    <dbReference type="GeneID" id="71983986"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04108"/>
    <dbReference type="OMA" id="GHHFAQF"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046354">
        <property type="term" value="P:mannan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31646:SF1">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE MNN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040408345" evidence="10">
        <location>
            <begin position="30"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="495" mass="56569" checksum="36A7702AD6CAA5A9" modified="2023-09-13" version="1">MLRLRPLITLLVASICVLGLWTLWHGSLGQEPTPLTPAQYKASGLTDNIYTNGNTKPDADDWWLHFEEVLKLKPVSMKEAKAGCAWNPQDLERVNFQFDGGENGFVDTAWVRNDTSDLVLDARRAQWQDFMMYGTIPYGDISSKLDGRGIVIVGGQSQSFHRVKVLLRQLKRLGSSIPVELHYWGDEMNEEKKQELSTLWPLITYNDLSSPTNIYHVQLGGIVHVNYQLKTAAILNSNFAEILLMDSDNIPTIPPEDLFNSKTYKEHGTVFWPDIARTRVQNPVWPITNTPCRKDEYEQESGQALIDKRKFWYHLQLAMFFINDKNSEYYNNILLGDKDTFRFAWHALKTTYGRPAHWLATVGIKMAPDHFCGHHFAQFHPDREDGRVVFMHGGLLKTMDKQVMTFLRASHGGIFHAYKTGTKPYDAEELTRAEIKFDGASYWKHKPESVGVQMCTDMKDVEARPFGELVQGFNEVFEEVGGYWLIDSGEFSSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH90</accession>
    <name>A0A9Q8LH90_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761816.1">
        <property type="nucleotide sequence ID" value="XM_047905402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH90"/>
    <dbReference type="GeneID" id="71986132"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06254"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="15338" checksum="FA8D6BA59489D2BF" modified="2023-09-13" version="1">MSTQSTRTPPTSTPEKAAPPSNKSPPTTPNQSQGNAGTQDSTDFLDQFIDNFDTPDSPSAGGSQKTPAKKKKRVGWAGKTKGYSYKVSKQGKSKGTGPAKASSAAPRRVYKHTELPDIAAGDLATTRSTRSAKGEQTFHALPYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHM3</accession>
    <name>A0A9Q8LHM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761159.1">
        <property type="nucleotide sequence ID" value="XM_047903193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHM3"/>
    <dbReference type="GeneID" id="71983923"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04045"/>
    <dbReference type="OMA" id="HEHDINT"/>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="4">
        <location>
            <begin position="275"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="358" mass="40957" checksum="98C48BEC3569667D" modified="2023-09-13" version="1">MVQELKGLGIEVMISVWPTIEPASENWDEMLEKGLFIRHDRGPRVTMQCVADTTHFDATNPEAQKFVWSTVKQHYYDHLIKLFWLDEAEPEYSVYDFDLYRYHAGPNMQFGNVYPREYARAFYEGMAAEGQKDIVNLLRCAWAGSQKYGALVWSGDIGSSWSSFRNQLAAGLNMGMAGIPWWTTDIGGFHGGNRDDSEFRELFTRWCQWGAFCPVMRLHGDREPKPPGQETASGAPEEVWSYGPDVLKICEKYIKIREEMREYTRGPMKEAHEKGTPVIRALFYEFPQDAKAWTVETEYMFGGKYLIAPVLAAGQRRIKVYLPVGALWKSWDGGSSYDGGSEVEVDCPIETMPVFVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ07</accession>
    <name>A0A9Q8LJ07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762390.1">
        <property type="nucleotide sequence ID" value="XM_047905354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ07"/>
    <dbReference type="GeneID" id="71986084"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06206"/>
    <dbReference type="OrthoDB" id="5422024at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15940" checksum="1AE90C8A6164A7E1" modified="2023-09-13" version="1">MATRQELLEDVQHNDTLRRERQKTRYDRSITADTTFHPRQAVMLEDTSNKGKRRKLEATFRGPYIVTGYGGEHRRSYTLRQLNGKPIKGHFYGDHLHLFKARWGHLIPPNEALFPEYQLLREPRRRPETRVASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ64</accession>
    <name>A0A9Q8LJ64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762821.1">
        <property type="nucleotide sequence ID" value="XM_047906869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ64"/>
    <dbReference type="GeneID" id="71987599"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07721"/>
    <dbReference type="OMA" id="APMAYEV"/>
    <dbReference type="OrthoDB" id="10482354at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="18336" checksum="9795BF387852AA08" modified="2023-09-13" version="1">MPRTVTETITVTRFGIEGPPTPTPATNPSSAPFTPFEGFGHALTHVGLPAIGSTIMFLTTTIAVFLATAAVTFLILQIRPPLTKLYSGRSPTVSAAEDKKTALSAARSVTFCHVVTVLALVLRMREALAMLAPMAYEVCALILAIEVGCVVVLGGVWGIVKVVELGGTAAKGEKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ86</accession>
    <name>A0A9Q8LJ86_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762768.1">
        <property type="nucleotide sequence ID" value="XM_047905097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ86"/>
    <dbReference type="GeneID" id="71985827"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05949"/>
    <dbReference type="OrthoDB" id="276515at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41349">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41349:SF1">
        <property type="entry name" value="PROTEIN CBG08683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040339533" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="230"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="504" mass="54995" checksum="1AF0559BB4164860" modified="2023-09-13" version="1">MWARSCLTALFFLSSSVLAAPSQTTVERQTGTLSQDPAGQALTFEYTTSHPFDTYWIGLYHASGGGPANEEYVAPSLVWSYAPGTPGTVTLSDDALEPGDYQAFFLAQDRYEWLAEPVNVTIEAPAADIDFPVESATLHNARQGDKYTANIAGLVLGQSQDTVIFTKVSGEDGINVSQDGLITGTPSSTSQVPAELTISATASNGSNNTIRLTIPVRLKPQRLVSDLKVMSYNLWHGGAQQLRFLLDSGAYVVAQQEASPDHAKRLGQALGWHHYQSSGSVGVISRYPIIEKYGQISASGGVRIDLNGGRDDDPVEINVWSAHLGYTPYGPYNFCFDNMTKEEVLAREAESGRIPQITAILDGIQSQLQEADRVPVILAGDFNAPSHLEWVPSLQEKNCDNDSLDWPTSILPTEHGLIDSFRVAHPDPAREQATTWSPVFPKHNGATGRDEPQDRIDFVYHTEDRLRVIGSEHLIVGDPAPSPGHKENEWTSDHAAVLTHYELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2K0</accession>
    <name>A0A9Q8P2K0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">CLAFUR5_02271</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="25" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755391.1">
        <property type="nucleotide sequence ID" value="XM_047901419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2K0"/>
    <dbReference type="GeneID" id="71982149"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02271"/>
    <dbReference type="OMA" id="PVQKDCD"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000039">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="816"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="867"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="913"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="965"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="998"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="UJO11025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1065" mass="117254" checksum="D45DE74FEB92C3E2" modified="2023-09-13" version="1">MGQEPKQVADSHVSGQSNKPLSKPPHALKWKEVAEELQADIDDGLNASEASKRLEEFGRNELGDGKKVNPGKILVRQIANAMTLVLIIAMIVSFAIQSWIEGGVVAGVIFINITVGFFQEFQAEKTMDSLRSLSSPTAQAVRNGQSNSIATVEIVPGDLVELKTGDTIPADVRLIDAVNFETDEALLTGESLPVRKAHNDVFDTETGPGDRLNVAYSSSTVTKGRASGIVFATGMHTEIGTIAAALRKKDSRVRPVKRNEDGKAKPYRYVQAALLTMGDAVGHFLGVNVGTPLQKKLSRLACLLFIIAVICAVIVLAANDFRNQREVIIYAVATGLSMIPASLVVVLTITMAAGTNRMVERHVIVRNLRSLEALGGVTDICSDKTGTLTQGKMVAKKAWIPAEGTYTIEESDEAFNPTKGAISFSEKEPQHIEPQEKDKQSSYAELLQNSEALKDYLRVASLANLATVHQTDSGTWNARGDPTEIAIQVFASRFQWNRRASVGGDNPAMKLLVEFPFDSDVKKMSVIYKDLHTDKMYAFTKGAVERVIASCTTYNNKKGDSVEITEEYRDEVLQNMEALAKHGLRVLALASRDYNESYVEGKEIDRSKVENDLVFRGLVGLYDPPRPESAPSVRRCHEAGIEVHMLTGDHPGTARAIAGQVGILPRNMSDISKDVADSMVMTASQFDALTDDQIDNLPVLPLVIARCAPNTKVRMIEALHRRNKFCAMTGDGVNDSPSLKRADVGIAMGQAGSDVAKDASDIILTDDNFASILAAVEEGRRTFDNIQRFVLHLLAQNISQACVLLIGLVFKDDENLSVFPISPIEILWVIMITSGIPDMGLGFQEKAPDVLSRPPQNLKRGIFTIELLVDMVVYGIWIAALCLTAFVLVLYPWGGGQIGIRCNESIGDGCGTIFRARATCFACLTWFSLFLAWEVVDMRRSFFRMTPNSTHYFTNWMRVVWRNQFLFWAIVAGFALIFPILYIPVISGQVFRHTGISWEWGIVFVASALFFLGIEAWKWCKRVYFRRQKAQKAQKAGRSGSVDLEAKVFERYLTQSSMGDEKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2N9</accession>
    <name>A0A9Q8P2N9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Inositol transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02074</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755479.1">
        <property type="nucleotide sequence ID" value="XM_047901222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2N9"/>
    <dbReference type="GeneID" id="71981952"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02074"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="97"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="66106" checksum="CC16EC59103FECEC" modified="2023-09-13" version="1">MDEKDSKAVEATQATNVEDATFEEARRMSAEKYQEAIRSGSIPKVKSQSEAIEIAHNCGWEADAVIEELEAELQARGDKKGFFDVEFANPKHFTWLLVIFASMGGLLSGLDQSLISGANLFLPDDLGLTSQQNSLVNSGMPLGAVAGALILSPANEWFGRKGAIILSCILYTVGGALEAAAMNYGMIVAARVVLGAGVGLEGGTVPVYVAETVERRLRGNMVSLYQFNIALGEVLGYAVAAMFISVPGNWRYILGSSLVFSTIMLIGMLFLPESPRFLMHKGQTLDAFAVWKRIRGTRTSEAREEFFVMKVGQEMEDQEIAEGLGSKRFPWMDFFTKPRARRAIIYANMMIFLGQFTGINAIMYYMSVLMSQMGFDKYESNYMSLVGGGSLLIGTIPAIFLMERCGRRFWAIAMLPCFFVGLVLVGASYHVPTMGGREGVYLSGLIIYEIFFGSYACLTWVIPSEVYPTYLRSYGMTTSAALLFLSSFIVTYNFTAMQNAMTKTGLALGFYGGIAVLGWFYQVFFMPETKDCTLEEIDLIFQKPTRQLVRENAASAWRTTQDLMCFRFRKVFIDRLTAPRSQSVVDNPVSKGEMLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3X9</accession>
    <name>A0A9Q8P3X9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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            <dbReference type="PubMed" id="35471194"/>
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    </evidence>
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</entry>
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        <location>
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            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040310645" evidence="1">
        <location>
            <begin position="19"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="15161" checksum="612519BD949D46F8" modified="2023-09-13" version="1">MLFAFLTTLVLLIATTVGAPTTLDPNPDVLATLNSKTSTSSSRLLVPAPNTQNCLAAKHGVGNTVRVCYTITIGAIFDDGKGCDGVHDHVDSGTDGRLNHYTWECTGESGDGNEDYTRLYFCLLGSKDVSGMNEELEGNFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4W4</accession>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="13">Race5_Kim</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="FVQFNHQ"/>
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        <property type="component" value="Chromosome 2"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
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            <begin position="36"/>
            <end position="185"/>
        </location>
    </feature>
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            <begin position="209"/>
            <end position="290"/>
        </location>
    </feature>
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            <begin position="615"/>
            <end position="705"/>
        </location>
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            <begin position="716"/>
            <end position="989"/>
        </location>
    </feature>
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            <begin position="1184"/>
            <end position="1274"/>
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        </location>
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        <location>
            <begin position="1110"/>
            <end position="1119"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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        </source>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF12621"/>
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            <dbReference type="Pfam" id="PF13967"/>
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        <source>
            <dbReference type="Pfam" id="PF14703"/>
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        <source>
            <dbReference type="EMBL" id="UJO13289.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1283" mass="144413" checksum="6FC4A9B7FF272407" modified="2023-09-13" version="1">MDPPSPTATCESGIFGLINCNAGAATTNEGQTVGALVAAIAGSFVSLGVQLLIFLLLRLRLSRIYRPKSYLVPERERVPQPPGGLIGWLYPLFTTDNLTLIQKCGLDAYFFLRFLRMLLKLFFPAALIIIPILLPINKTAHADEVHGLDRYSISNIGKQFAHRLWAHTILAVMFVAWFFYVVFKELRGYIRVRQAFLTSPQHRIRASATTVLVTGIPRKWLTLEALSGLYDVFPGGIRNIWINRNFDELADKVSQRDKWAKNLEDAETVLIKKCRTKHAEAEKKRAKAEGRKAKTKDEKKQDKANEDAAAEQMAHGEGVSAGGEQRNQLPQGMQDILEEEEERQHDKMENQRNKNPFGAIGQGLDGVGQGFQKFGKGIGQFGNKIVGGVESELHKAGHDFDRTTNTLNTGGLGAGFATDDSLYRVPTAGDGPASPRPSTVLSRNVSPRLPGGSQIDTLPRQTRHPLAGQQGSSNSDDTLGVPDIQTTRPSGESRPREPLNIEEPPSHAAKRRPWDLFKNNDRSLVLPSPQPHIQEDDEFPLHDSGSDEKERKGSTEKNISDSKTTEKSHFWKKGDNKTTEYPQSFDKDWDEDQDEEPYWRRYMKPEDRETIRLPVFSATWWPALPLMGKKVDRIYECRRQLARLNAEIEADQNDVEKFSYMNSAFIQFNHQVAAHMCCQSLSHHIPQQMAPRLVEISPDDVLWDNMAIKWWERYLRTVVVLLISAGLIVFYAIPVAFTSLLNHITTLAQVVPWLGWLEKAPKTVQSIIQGLLPPALLAVILLLVPIIFRLLVKQQGVATGNAKELGVQQWYFAFLFIQVFLVVTISGGLTNFFSEAATNPGSIVEQLASNLPKASTYFFSYLTVQALSNSASALLQVGSLFMWFIMAPISDSTARAKWRRQTNLNNVQWGTFFPPFTNFATIGIVYSIISPMILVFMIFIFGLFWIVQRYNVLFVYQFRHDTGGLLFPVAINQLFTGLYFLELCLIGLFFAISGQAFPQAIIMIILLVATICYQWLLNVAFKPLFQYLPITLEDEAVIRDEEFARAQASKFAPLNQGDRADEDPRDIQDALEEREQREHDADHAAEDAEKRDVEQRRRSDTPGSAHSPDARTQGSTPRTGQGAWHERKDTAKPLWSTEKWKRVAPEAVGALRFLADGTRNDKPERDPEAQHTVGDVLFSGYADELEDLSPDERDVLVRYAFQHSALRARRPVVWIPRDALGVSDDEIKRAKKMSTVKVDNENGGKEEKTNIWMSNEGTALDGKGRVVFRRSPPDFSNIDLIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4W9</accession>
    <name>A0A9Q8P4W9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757642.1">
        <property type="nucleotide sequence ID" value="XM_047901999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4W9"/>
    <dbReference type="GeneID" id="71982729"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02851"/>
    <dbReference type="OMA" id="RPNAEQW"/>
    <dbReference type="OrthoDB" id="9985428at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="57"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="56304" checksum="69E09EDC4F503268" modified="2023-09-13" version="1">MTRAERELRARGTVHRAIPEILRSSPRAKHGISQADLIVDPQPGIKTPTGPAASAFRDDLAIRVIGRDTLQVAAHLSERPYASKRTTDGRKASDERPNVTIHNMASLTRPGGAFITGGNSQEEFLCARTTLYASLFDDFYALPDIGGIFTPDVLVFRDFDGMELPKRSRYFINVISAGVSRHPENRGRYDGREESCSCGVSYCDRDRDIMTRKMKAVLRIAQSNGTRQLVLGAWGCGGLKHPVKEVAKLWRKVIAGSPRQRRPNAEQWDGIDEVIFAIPDPTHAREFRHVFDDILADDFVATSGSSTGGGVEADDAEIQRLIGTASSLELQIETAQSSFLKGRFKDELREVNHQIALGRAAKAAKEDDVTTEEDEDLEDDYVVTGFPGSDGEDNSFYRVGGTESDSDSEGAGSEVYEFRFGGPTGDSQTSQDELDELEEGIGWGGYSSSPKFNAQTGWFQGSIDQLSAHVLGGNKMGSASPRSPVLAGLDSDAPKTDVAVDGFLARFRRSDVDDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5F9</accession>
    <name>A0A9Q8P5F9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-hydroxyaverantin dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758314.1">
        <property type="nucleotide sequence ID" value="XM_047902214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5F9"/>
    <dbReference type="GeneID" id="71982944"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03066"/>
    <dbReference type="OMA" id="CDIRDWD"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF31">
        <property type="entry name" value="CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="33506" checksum="589BDDFE8A4D447D" modified="2023-09-13" version="1">MTISTEFDQSEAIAADATYDPSGLKGKSVIVTGGASGIGEQTMRAFVGAGAFVTFGDIAEELGQKLVQELGDDKVAFVRCNVVTWSDQLELFKTALDKSPSKTIDIVFANAGLNGPDNIFFQDENADEPKEPDLHVLKTNLIGTAYTAKLANLYLPRQPSGEDRDRCLIFTASMAGYMDQAGSPQYDASKWGVRGLLRSIRTTGPAQGVRVNLIAPWFVDTRIMSDEIKQKLRAGGIEFCDIQDAARAVLHFASTKHINGRALTIVPKSVSQRGYVDLQEDDFPEGELITQWQQVGKKLAHRMSKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5J9</accession>
    <name>A0A9Q8P5J9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">CLAFUR5_03510</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="25" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758571.1">
        <property type="nucleotide sequence ID" value="XM_047902658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5J9"/>
    <dbReference type="GeneID" id="71983388"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03510"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000009">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="251"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="546"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="1015"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="UJO14205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1113" mass="125766" checksum="A34A1B97DB66C215" modified="2023-09-13" version="1">MHQIHTPNTMPGVLTQSPAKVPSKRVLQDTTRSRQHQQASPQKKRKLEDSKPAFRQPGKRGPNGIGSSQPKSQFEEEVLEKLTQNLGSLKENNAEKDQQWSRPSLDGFNEKTDTVSFQAIDAEEGTLHGGKATVKLFGVTEAGQSVLLHVTDFLHYLYVAAPIAFTKNDCEPYKLFLESSMAQHSAAIQSVQMVPRENLFGFQGNQKSPYLKITVTDPKFINKLRTTIQSGNANYKGMWKVAEGGILTFDNIQYVLRFMIDTGVAGMSWVSTHGGKYHMIPDRDRQSTCQIEAHCHYRDLIAHPVDGEWQKMAPLRVLSFDIECAGRKGVFPEANVDPVIQIANVVTRYGEEKPFVRNVFCMDTCSLIVNTQIFEFGAEEKMLMAWRDFVEEVDPDVIIGYNISNFDFPYLLDRAAFLKVGRFPFLTRLRNMKSMARDTNFSSKQMGNRDTKATNTNGRLQLDLLQLIQRDYQLRSYTLNSVSAHFLNEQKEDVHHTMITELYNGTPESRRRLAVYCLKDAYLPQRLMDKLMCLINYTEMARVTGVPFNFLLSKGQQIKFISQLFRKALEQQLVVPDLKSEGSDEQYEGATVIEPTRGYYDVPVATLDFASLYPSIIQAHNLCYTTLLNKNAVEKMQLKKDDDYIVTPNGDLFATTKVRKGLLSQILEELLGARKRAKKELAVETDPFKKAVLNGRQLALKISANSVYGLTGATVGKLPCLAIASSTTSYGRQMIEKTKEEVEGKYTIANGYSHDAQVIYGDTDSVMVKFGPNDLAKAMELGQEAADYVSSKFIKPIKLEFEKVYFPYLLINKKRYAGLYWTKPDNYDKMDTKGIETVRRDNCRLVQNVIETSLKMLLIDQDVQGAQDYVKETIAELLQNRVDMSNLVITKALTKSDYANKQAHTELAERMRKRDAGSAPALGDRVAYVMVKGAAGSKGYEKSEDPMFVLEHNLPIDTKYYLDNQLAKPLGRIFEPILGEKKAGQLLTGEHTRAISVAAPTMGGLMKFAKKTETCLGCKKPLASKEEQGGAVGEECRPRFAELYQRSLSKVAELEVRFNRLWTQCQRCQGSMHNEVICSSRDCPIFYMRMKAKKDVEDAGKEIDRFDRDATLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5S8</accession>
    <name>A0A9Q8P5S8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HC-toxin synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758796.1">
        <property type="nucleotide sequence ID" value="XM_047902994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5S8"/>
    <dbReference type="GeneID" id="71983724"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03846"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="109"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="318" mass="34380" checksum="4C64AED25DB09853" modified="2023-09-13" version="1">MLAIVKAGAAVLPLAPKDSNSRLQALIEHSECSLIVASPIQATRIKGLDLCKQSAGIQIMQIDADAIADCCRARRMPHSSSYAPIAPTLPSDLAYVLFTSGTSLHSKGMMYTEYTFDNSIQDVFGTLSAGGCIVVPSDAERANNLLEFCEVHHVNALHITPTVLRLHFAQPSTTSIQLKSLVIGGEPVRDHDLDILRQWAALCKDLRAFVAYGSTETCIDCIARQVTSSEALAPVNSIGSPISFLIWQTWLVSPLTQRLAPVGAQAELYVGGPAVARGYLPSNEVSQTGFLGFQDPFYGKSVNVEPKDQQPHIRFPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P681</accession>
    <name>A0A9Q8P681_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758918.1">
        <property type="nucleotide sequence ID" value="XM_047902956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P681"/>
    <dbReference type="GeneID" id="71983686"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03808"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12669" checksum="7B186488EA8CC340" modified="2023-09-13" version="1">MNTATQAAMLAAGPRAGQRWTAADDATLLQMREQRQPWRVVAQALQKLPLACRLRMNQITKKRRRAERALKAEQDALALAALQRLSVSGDGSGGGNRNRNDGSSNANAEGSNGAQSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7D7</accession>
    <name>A0A9Q8P7D7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760401.1">
        <property type="nucleotide sequence ID" value="XM_047903259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7D7"/>
    <dbReference type="GeneID" id="71983989"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04111"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="3"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12313" checksum="12312409770A3D36" modified="2023-09-13" version="1">MDHSPLGGLPPEVLEIVLLALPLKDALNVDILCRELEAVVKASPRLQHELFFKPQGKLLAQQWVDDDGAEVGRDFRLQYTTTAAKPASPPRANPSPPILVTSTDDPGPSPRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P810</accession>
    <name>A0A9Q8P810_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761030.1">
        <property type="nucleotide sequence ID" value="XM_047904243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P810"/>
    <dbReference type="GeneID" id="71984973"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05095"/>
    <dbReference type="OrthoDB" id="5957391at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000059">
        <property type="entry name" value="Histidinol-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="35895" checksum="A49C97447DC530EA" modified="2023-09-13" version="1">MPWSHHSHSGQFCGHATSTLEEVVQTAISKNMSTFCLTEHIARQQVDFYPGEAEEHTQETLASLYDDFYHEARRLQQKYAEQIQLLVGFEGEWIRDYSLPLIQDLLEKYQVDLFVGSVHHVHTLPIDYDTEYYHKARHVAGGTDERLFEDYFDSQCDMLNALKPPLVGHFDLIRLKSDQPDRSLKSYPRVWEKILRNLNFIASYGGVLELNTSAIRKGMLEAYPQSEICKAFKALGGRFTLSDDSHGIDQVGLNYDKTWNNNVMRAGLTELYRLTPTTDKSKVHDERFPHVCWEKVWWSDVRDHPFFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8L2</accession>
    <name>A0A9Q8P8L2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">L-type lectin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05526</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761721.1">
        <property type="nucleotide sequence ID" value="XM_047904674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8L2"/>
    <dbReference type="GeneID" id="71985404"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05526"/>
    <dbReference type="OMA" id="GCTADIR"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000095">
        <property type="entry name" value="Lectin family integral membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040481021" evidence="8">
        <location>
            <begin position="24"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="30"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="35897" checksum="0B7394D719D5E6E0" modified="2023-09-13" version="1">MAFHSTSWITAILLAVWSCFATAQESDIKSIRLRTHSLQTPYLDTDMQSRWWDFGGSAVIRADQYVRLTAQQPSQSGWIFSRVPITATNWEITVDFKIHGTGSLFGDGMTMWVTKERAEQGNVFGMKDNFEGLGIFFDTYKNNRPGVVFPYVMAMLGDGKTPYDQANDGKANELAGCSARGLRNPDFPTKAKITYFQDKQLTLELMYKKEDEWTKCFEVPNVKLPPITYLGFSAETGELSDNHDIIKVETKNLYSPSGQAGTGGASGSKDYSRNKGKPQKVKSSGGWLWFFGKFIIFGLVVAAAYIGYTAYRTRRRDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P901</accession>
    <name>A0A9Q8P901_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-transporter-regulating transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762141.1">
        <property type="nucleotide sequence ID" value="XM_047905568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P901"/>
    <dbReference type="GeneID" id="71986298"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06420"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF25">
        <property type="entry name" value="ABC-TRANSPORTER-REGULATING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="662" mass="73802" checksum="C8FF486744854ADB" modified="2023-09-13" version="1">MEPATFDVGSGINTESDTSKKRKRAWQACDHCRARKIRCNGETADTPCPNCIDRGVDCVTTISQRRRRRPIGTTANIFNHAQPVPSLTDSMAMGHSPLCPYSTLGQSEETTASIQVDDDGGETPDDLRERSSVLPSDMTNWEYHGPRSFLSVCSKPAVKWVSEQTGRADFADIASHFASDITRRLKMDADISPTRAPEPDAETAWHYTEAYFTLALDASLAALHRPCFERQLAAHLAGNAVDNSPTWHALRNVVYAFGCRIELSKNCSFKDASQQAWLYFENALAVYARLLFYKTSIMGVQVLTLMAYYTQNIGTPCLEYMLSSDAVRLALAKGLHRAAPLSQGLTEQDVEQRNRIFWAIYCLEKQIACQASRPSIIDDEEVTCSLPRITSPSDDAFSIAYCHSLIRISRALSTIEKRLSAVRCSRMDVTATVQTVDELHSELETVKNAPQNQFGLALGTKIDVTNSPEDFKLDQLVHLHYAYHTAMLNVHTIWSYPWIRALVGLSAIDKLRDYVLRSSDVVARVSRDMIAITEHIHFKAHATVPVAFFAPIYAMISLFVYCLDRQKSLADLAVMDIGTGYFSKLGLETDFLISVPFVRAITSLAYGFEESTLATNLHNHQHLAQGGMNASQSLGADFWNVGILDAETMVHLEDWSTFPRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9J6</accession>
    <name>A0A9Q8P9J6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06292</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762382.1">
        <property type="nucleotide sequence ID" value="XM_047905440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9J6"/>
    <dbReference type="GeneID" id="71986170"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06292"/>
    <dbReference type="OrthoDB" id="3251668at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF32">
        <property type="entry name" value="ARGININE METABOLISM REGULATION PROTEIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="474"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="460"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="581" mass="62787" checksum="55DEC09D366297F2" modified="2023-09-13" version="1">MQSRVTSAHCSMSSRLSFAACSRAGGPTDYHGRFSNGNLAYTARGPYTSLAALTDALAAEIAAATQSSIPECTTCELSLDLNATLPLIRPTIGPYAQGQPNDIPHEFKHAPTVPDGADPSKVHPGATCATIVNITDPSGRAIVQRAASRGVIQAVEAADGYRYSFNNAWTAKDEEGSRFSFICQDSMQNKDRHANGFTRTTKHLKGETNEVRGPRKPTYDCKGSVSVKFSSGKQSVDVYYRHYAIHQTVAERKLPPRPPPRSKEAGAATQSTPKEGGGLLPTLQAETFANTALAMVNDQRPIIDNQPPLAMRSHAGPSISRPLKRKRESLPPPPPAPKPRDPNKPPSLSELLASSETANKPASPVEALRAVPSKFPPPVAYELPSWQTPPPPMTATPSNQPYPPPYPPYPPPGKIAISATPRQGPLSQQSRPGAPTGTPGSGHALFTTMKQVWQQPQTPVFHSFGPQRQRGSKACSNCRQRKTRCDEAKPCGACVKSGRTDCYSIEQPPAPESTPRREDFAGTWGSLSQPGPPPQLKEWQQQQQQSQANSPWPAAQQQPPQPQATTAARRDDSPDPWYPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Q9</accession>
    <name>A0A9Q8P9Q9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762784.1">
        <property type="nucleotide sequence ID" value="XM_047906159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Q9"/>
    <dbReference type="GeneID" id="71986889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07011"/>
    <dbReference type="OMA" id="TINWQER"/>
    <dbReference type="OrthoDB" id="10281566at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="15768" checksum="C4DC2AC20A8BD201" modified="2023-09-13" version="1">MSTINWQERLTSGILPHGFTKATAYTLEPPHQLLGSTSDDFTLSEQDLATLHKLLVEQDCNQRDNALTFENGSYEVVHPGQMFALNDKSVYAVNGRTAESHGVVASKTWTSLIVAWHGNTGKSANELIRGYEEFVRSLRGTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9V5</accession>
    <name>A0A9Q8P9V5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 7B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762817.1">
        <property type="nucleotide sequence ID" value="XM_047906873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9V5"/>
    <dbReference type="GeneID" id="71987603"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07725"/>
    <dbReference type="OMA" id="FWNLVHI"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306:SF7">
        <property type="entry name" value="AHBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="511"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="573" mass="64488" checksum="25B296D0006CFDD4" modified="2023-09-13" version="1">MGVPHQDDLTLAQGETGNVSFLLEHRWTIASFMLCVMILLTRISSSLNSRSKTAGEHGAATVPAVPYWLPILGHIPNMAWDADGFVKGLRAIYDCGIFSLNFGGTRHNIICHPGLATAVLNTKASNANNESVSKRLMDLVFGFPSNELEKYDVAFEELHGLYRIIQVEPGLGKMVEQTARKTKENINNLVTFMESPVDQMPWEKVSNINVVESPNGERVVEASLLPLIRDFCAFTANPSIMGSDFLENNPQFFDDIWILDRGFLLLATGLPRWAPIPTLTRAHIARRNNLRRLETFHAMMDKQWDGNNDDPKWSSLDDVGDLIKARMDIYCKYKLSIRARASIEHALMWAANANSNSLVFWLVNRIYEDKALLAMIREEIAPYVKVEQVETGLPIKEPPRITSLDVEGLCDKCPLLKSCYVECLRLDTGSWSFKSVKSDFVLQSREKEAQPWLLRKGEYVHVAHDLHNTDPNHFENPAVWKADRHIKYDDKRVGTADMGSIRPYGGGTSMCKGRAFALKEVMMFTAAIVSMWDIEAAGGGTWKMPKHAKATGVYSTRDDTRVWIKARKMPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAS8</accession>
    <name>A0A9Q8PAS8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763421.1">
        <property type="nucleotide sequence ID" value="XM_047906551.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987281"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07403"/>
    <dbReference type="OMA" id="TTHSIEH"/>
    <dbReference type="OrthoDB" id="3647690at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070823">
        <property type="term" value="C:HDA1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038609">
        <property type="entry name" value="HDA1_su2/3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021006">
        <property type="entry name" value="Hda2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11496">
        <property type="entry name" value="HDA2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1443"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1371"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="743"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1170"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1503" mass="163794" checksum="2211B8A4EA0B14A2" modified="2023-09-13" version="1">MPKRKRGIATSTSKASTSSKRVKRAPTTDAPGPSASPHPHGTIDYEKDYKLRAIINEKGGKYLIDWEDDSETGEKYEPTWELKANANELAIEDWEATKRARVAAGTSATPQPKERGRKPKKAAERLSAPARKPGRSRRVIDSSPIDSSPGPHAETVKSEDDDVVPPPSDSGPVETEPELEIDESEPENDNESLPSVPADNPLSNGIPLAVQLSDPPSRFRAGAYQRISEHGDSSRPSSRPSSRHDSSLKSSTSLPITTEVLRSTADEPVPSQAQPQPSSTQATGDQNTSLVVPDSQSQQHFHETSSFKVFSPVPELETAVSTQDPATSQVQPTQAAEPEPEPEETQEGEAQSRNFPLAVVEPVRGDSVSQEVAPQPRSPIADEAGASGENFATKEAEEVQAPGEPQEAVSKPEQPAAYETSASDENPATRIAGEVQAPNGSQEPVSKPDQPLADKTNTSDESPAIRSDSEQELAVTASHVQASDQSVAAGHDITTTDEPTRQTVEEQSEGGAADEDLHITSVVEEQPTIQASGASLEEEQPRSQQRQDPPQTQSGAPSTSEQSRDYIVISSENEHGQNSSNDRSNDSAQFLSQAKFSPPPGGQRPPSSSALQGSVEDNSQPVELPPGTAPASQSETNGHSQQATATQSSFPFATQLPKPSSAPKTESKAPGSATKRRAIFAPFPKRTASRPPSVTLGTSVDTSSFPPIPSQPLQTLGESAPPKLPTPTPSISNTSPERMDPSAASQPATPSLSSQLKAIRESRRQTRRSQTPATVINNAQPISSLPPSMNAEVAAARMASPGLSAPDSGRSPSAVPAVEPESPVIREEMNTSERYETLLPQAQSNGLDYQEPQTRPLTNSNEVTMAAPEDPNEDPEVANMHLVPIPFNGPQRDSYSNNIYHHNAAIERILAERHPAELLLEEAEKLLQRLRDLATHPDLTNHETLSQASEPDRQAQWDVDSSGKFCFLQKLFDALQELSQTTHVAVAARGHRVPDMLETFCSGWFYTYSRSGQDHPSSQPGKDKVRITILDLDKETEMPQDADIVISMDGTTDYRHRIIRAARRHTKGKGMTGTNSWAMLLTLVVPKTVEHIERCLASDLPRAVRARVLLATARKLQHEACRKEHDGQDYAKEAARKLVEYLDDPEATEWPLGSLSPIQDLDSQTQTELEVSHADVSTDHDSNGHPSKRPRLSGDEIQQLPTTINPQDMEITHVSDSLGSKTTQPSLNAIFATPTGPSVREQQLEAELDRVQGRLEDHVRDLEKVQYRNEEQRADLSHKSRERDGAVSRVRNAIERMNVAENNNSTLKAERTELQKQLDAANAKLLDHSVPERVDFERLRLEAEAAHVAKAKADKSVEKAQNEMEWFRSMYQDSSNKARELQAENNDLQARLAIAEKQASGEMARAQQISQDMHWKTLDRENRQLRSRLKDREAGIKFRDEEITRLKESTRGRMGTRQSSVPRSPRLGSPMKLAGGRGSRQASPAAGEVRGKGGHPLRNSAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBJ1</accession>
    <name>A0A9Q8PBJ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
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        </source>
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</entry>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO20038.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="26873" checksum="50E36CE14CE496C3" modified="2023-09-13" version="1">MFMLRYLLNAITREQFRVAYRAALEEVHQADGISDDTKHHLIKNANKLAHLAIRTRSASSGFKRWRDVQEYRNAMRAARLLKRDSELHKGREVLSYEETQLICGLTTHFRERVDEPLYKLYYNEDEPDYELYDYDEDYLNDSFLAMLARLDACDEEKRKQISYLKGHMLCVTAEERRSMEPALKHMEQSVALGDQWREWRKKWMGTEIEGSGSSVLDVEASSLLQLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE26</accession>
    <name>A0A9Q8PE26_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAD1</fullName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_11167</name>
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    <organism evidence="17 18">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <location evidence="2">Spindle</location>
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        <subcellularLocation>
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    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD1 family.</text>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="C:mitotic spindle"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:cell division"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DASH_Dad1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD1"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00030566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO20778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="83" mass="9206" checksum="B9C7ADFFA6967214" modified="2023-09-13" version="1">MSDPTKETYFQQQRQLLINDVAASMENVLQNINKLNRSLEGVIAVGNEFSQVEGLWSQFENVMAKDAEKEEGKDANEGAAEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE44</accession>
    <name>A0A9Q8PE44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765154.1">
        <property type="nucleotide sequence ID" value="XM_047910066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE44"/>
    <dbReference type="GeneID" id="71990796"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10918"/>
    <dbReference type="OMA" id="WPGTQAM"/>
    <dbReference type="OrthoDB" id="5419922at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="955" mass="104314" checksum="7937C3FA2DECAC9B" modified="2023-09-13" version="1">MTSKRDLCFRDTPDHGHGSHRPRGYRWNCLSDFQQTPAFRHIRYDECLAPEDDGLLTDDEDDFALPERAAKRRRVEQLADDFLNGVALEIHSARLVPEALRTAVAFSSFPRPKDFRYAIADIETQNDSDDIWEDVDDDQDIFRRLRGACKADEDDSGVFVDGTVSVEELEVTEVQAQASCGPKRRLRSTQVTAGPSEEALRVAAALRNRKLRQTITSLPVESQPQSCPPPVIPETQTQSSESSLDETASDCGPSPTPAWTSSKWLKTGAFQPKKHVDEDCSRDELGTSSIFTLSQKSRNRERPLARGKAGPSSAASGSFSTAPSATAASGISESFVLRVGSLQVPESSNVTHAQYDEHSVETSELTEFQTAPQDHGGAKSDDIIPDDDSQSRLLRRQGLRVAPRKSWVAMNDISEHTEEPTFVSPEERQPTCDETVGGVNAIDEETSMQDKQPKGRKTKSTGCATEAVLPRRSSSRRQSAPSESQSAAEAVQRPHRDKGQYIEVEVNGFSPLVLRKRGSKHNKERGKKAEPPQTRETLSESTPRRKVTFSSSSPGKVRPIPVPAPAPHTPLVDEHLNTILPQAAGSGRRSSSVRRALRDELEASGAELSRCGDEASSQPEPIRRPALHESQEDDDAVDQAPAVPETQWPGTQAMLAQAQDDMFTSPEKSNSDQYLGDKSSPQLHGPRPNPSRSARKPLKQLSQEPVALPSTQALLQDWQPWSSIKKPGVTREFEESLESPSLAKKPTPRTVSASYLAVAKTAAARSASGSIRSRGSASARRSSLRFSMSFSESPEKIDHQSEPNAAVAQEPKAASQPSFSPLDNDMEKHDDTVSDLDIHSPKKTTRGIFSSMRLTGTQKSPVTGNAASGLSKPPTRRSSSGLKSTLSFGISSLDLPVHRDAESQQDTILPPDSQDSQTLMQNAQQVLVDEDSQVLARTIMEVTTDVLGTADTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC1</accession>
    <name>A0A9Q8PEC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst complex component EXO84</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11241</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Secretory vesicle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO84 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765218.1">
        <property type="nucleotide sequence ID" value="XM_047910389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC1"/>
    <dbReference type="GeneID" id="71991119"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11241"/>
    <dbReference type="OMA" id="AAWLPNR"/>
    <dbReference type="OrthoDB" id="642193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25345">
        <property type="entry name" value="PH_EXO84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="8">
        <location>
            <begin position="503"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="730" mass="79745" checksum="1E45F1E17E98B160" modified="2023-09-13" version="1">MSESKGISLRRKKTSAKTAKTAAARPTISAPVQQHQQHQHQQHQQGDSRSASAVRSNSAWTVATQDSGTSNATSRERPKLGGDQTSDLVKRRYSTRFAGGIPQDGAAPPMPAMPSMPSQYAGDAASLRGGSRPPPSRDGRASPEKGKGRLKVDMRALKDPNLQVEKYVQNMLADASESDIHAYQKDLQSVKAHTDSDLQHNVYQNRTQFIKISKEADKLKSEMRTLRTLMTELTGALGHVTSAGGAELSSSSTLSVADRKRANRSSVANLEAMWSTHLQTLWKRVEGSQKYLPALPGRHIIMESQRWVELNAATWKPRRRVALVLLNDHLLVASEKKRPADATPQGKGNRMSMYQPAGQSQTTLVADRCWSLHDVSLADISTRSSTAIGHNNTKENRAIANAINVRAGNESFTYATGDSTDKAGLIVAFRKAQEDQRKQLAAEHAGREKALDDLASLTGRDARSLKKAAAAGNDLIGEDGKLGGLSRSNSVLVDADGRPQSIRWVESQIDGLDIDIALQRFEEAVSRVEKLRKMARGIKGNAMAQEIILAKVNERASRLANSVARQLSYSSSGMERTKENVSWLLRLGFEELARQTYLASRTETIRARTRQLPFTGALEPYLHALAYTTFTLLLHTFRTFNQSFPTTSGSAVVRWAKERVDEFNAALERQLSSVVRESEIWGICIQTVKEQAVVLAEVGVDFGGLIARGLSADAAAAVNGTQPIGLGVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEF1</accession>
    <name>A0A9Q8PEF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765295.1">
        <property type="nucleotide sequence ID" value="XM_047910694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEF1"/>
    <dbReference type="GeneID" id="71991424"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11546"/>
    <dbReference type="OMA" id="TTMRCAP"/>
    <dbReference type="OrthoDB" id="10308424at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="19622" checksum="4BE488020E638CD9" modified="2023-09-13" version="1">MSESRPWLHDLVDIRQTELANDLPHEIETLSRNVHSALNSGHFDHNIFTRVADHFEHVTPDFSGFTDVGRGVMLLQDIINARKKMTEANPGYRSVVTDSHTYVDKNLQLADVMLVIRHVGLPGGREEDGVQILRWRKGKGGWMCTRSTTMRCAPGLTDEVTGYEESSSSGDFVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEW7</accession>
    <name>A0A9Q8PEW7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxamine 5'-phosphate oxidase family protein ustO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765597.1">
        <property type="nucleotide sequence ID" value="XM_047910360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEW7"/>
    <dbReference type="GeneID" id="71991090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11212"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="OrthoDB" id="539398at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="36"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="260" mass="29293" checksum="BADAA5685A60FA24" modified="2023-09-13" version="1">MVKYYDSISPDLQEWALRQDLFFIASAPLNGKHVNCSPKGQPSATLTIFNGNSVGYLDATGSGIETISHVYENGRATIMFCSFGKSPRIMRWFCKGRVIEVDHPEYEMWLKRMGKVEYPSMRAIILFDVFQAQTSCGFAVPLLSQRVDPARPDDGIRGWFEERKTLENFAKKGIPYPKEMAEYRVKMNSKSLDGLPGLRLALKNSGKSVLSEQSRARLSTILRQREAMLLGALLALIAVMLLQFSAKLLRRYMPAELQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFA9</accession>
    <name>A0A9Q8PFA9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11055</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765742.1">
        <property type="nucleotide sequence ID" value="XM_047910203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFA9"/>
    <dbReference type="GeneID" id="71990933"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11055"/>
    <dbReference type="OMA" id="QWIFWGY"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF15">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="37"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="486" mass="52486" checksum="65EFE3D63A8BA580" modified="2023-09-13" version="1">MSTPTAPEFNSSEPRGGDPLVVDVNAQYAGLEFHYVYLIFCAFIVWLIIPGIGLLYGGLARRKSSLSLLFQSLMVAAVTTFQWMFWGYSLAYSRTANAFIGDLSNSGLMKVRAAPSPGSAYIPEIVFCLYQLLFCACTVQIVIGGSFERGRILPSLIFSFFWATIVYCPIACWTWNSNGWLYNLPSLDFAGGGPVHIASGWAGLAYAFVLGKRKHAGETSHKKPHNTTLVFLGTVLIWFGWFGFNGGSALNATMRSMYAAFNTNVAGSTGVLGWVTVDYIRTGGKFSVVGACEGAIAGLVGITPAAGYVSFWLAAVIGFVTAAICASLQKLNDWLNIDEGLEVFKLHGVGGMVGSFLTGIFADQTISALDGGTLAPGGINGNGVQVGKQFAEITAIGSYSFVVTCILLLILKYIPGMHLRVSEEAEMRGLDLDQFCDEQIGDWEFFEHQEAKIVTHGVPQHLPLSSAVSHEREAPKHDAPKSERQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFE4</accession>
    <name>A0A9Q8PFE4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765950.1">
        <property type="nucleotide sequence ID" value="XM_047908129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFE4"/>
    <dbReference type="GeneID" id="71988859"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08981"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="112"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="24459" checksum="8EB9D003FFCB1191" modified="2023-09-13" version="1">MPRALNRRNRSVHLAVILILAAIVYGFLVYHPESDRDAENFSTQDLQIKHHLTTPTPIVQSIESLQPSHKAIRTKHAHELQPIETPSPVVSVPDQKYSNQTVVPSSDRTCARPYRVKQGDSISFITHTQNVATVDLLAENGLRFPFESTLAPGSIICLPNTCHIVHIVGADKCYLFAPTGIVQPEILAWNPHAAKGLESGPLCFDLGPSGEVAFCMSKPGKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFG4</accession>
    <name>A0A9Q8PFG4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765882.1">
        <property type="nucleotide sequence ID" value="XM_047908270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFG4"/>
    <dbReference type="GeneID" id="71989000"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09122"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="313" mass="35731" checksum="1EF68DAA219B9800" modified="2023-09-13" version="1">MDNEFYLIQRRHQLGQLLRERYKSAEKALNEKLVKIVNEQCTQHYDIVDLLQPFSHAKNSTGWADWRKLSSAILATSSKDAPGRHAVHDTLRLAENAKLNRNEHKQLFEDANEGHDEWIDVLAQVARELWFIQALFHQDTLQPALPRELLTTMQHSGTRNFRLGPVNPYKVLKRTAGSSDESQGTSSGQHSSEDSRHDTVMAQPTDEKEKTRPVAASSSQTDALGLEMEVPAPVSHILHQDEEERQLHKDVDEAVRSKRSLKRERQKEARKAEKERQQQLEQGREVREVGKVVGGMGLVCFGLFVWSRIKHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFJ1</accession>
    <name>A0A9Q8PFJ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit KXD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">KxDL homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09297</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the KXD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765919.1">
        <property type="nucleotide sequence ID" value="XM_047908445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFJ1"/>
    <dbReference type="GeneID" id="71989175"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09297"/>
    <dbReference type="OMA" id="DRMQDVF"/>
    <dbReference type="OrthoDB" id="4089816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051390">
        <property type="entry name" value="BLOC-1_subunit_KXD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019371">
        <property type="entry name" value="KxDL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37787">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37787:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10241">
        <property type="entry name" value="KxDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="KxDL" evidence="9">
        <location>
            <begin position="90"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="20555" checksum="39E8136E0F9B0D22" modified="2023-09-13" version="1">MSTAYYPYQPTGSLPVNVPGKTPQNPYAPRHNRNSSAYSQLSASPPERPESVSSTGAGLYSAASSQYGGSDYESSSGATSVDLLDYMNDRLSQAYDPVPLDKNLARQAQMSGELNAKNRELLALQAQARARLAKTRANFAEGMKAAKDVQRDLEWTQKKVHALNARAAQKYPDQYRAASSRYPAPVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFP8</accession>
    <name>A0A9Q8PFP8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Yippee domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09314</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the yippee family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765941.1">
        <property type="nucleotide sequence ID" value="XM_047908462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFP8"/>
    <dbReference type="GeneID" id="71989192"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09314"/>
    <dbReference type="OMA" id="YLRCARC"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="58"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="264" mass="29036" checksum="38C729DFB6B21D11" modified="2023-09-13" version="1">MPFPSIPSPPSLFPTYLVPSLPFRRRKSSTDSNASTLSNDSLETGCPTSESYLSGHASHLRCARCLSDLALSTQIISKGFTGRHGRAYLVAPSTSSISANPTSLTTAKARNDALPNLPNTYTHKPVPRQLVTGAHTVGDISCAQCGSVLGWKYVSAEEESQKYKVGKFILETKRVCRSSVWEREDEGDEEGALMLQRRESEERKRRRSSCIVPPNEVTIMEELEFDSGDEDECDALFAGTWTPQVARELRARKVGRSYGGVMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ9</accession>
    <name>A0A9Q8PFQ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765967.1">
        <property type="nucleotide sequence ID" value="XM_047908495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ9"/>
    <dbReference type="GeneID" id="71989225"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09347"/>
    <dbReference type="OMA" id="IVPITHY"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07380">
        <property type="entry name" value="MPP_CWF19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF4">
        <property type="entry name" value="CWF19-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="3">
        <location>
            <begin position="296"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="2">
        <location>
            <begin position="464"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="60464" checksum="4CD613F0E3D67BBA" modified="2023-09-13" version="1">MPKIIVVGDVNGQLTDVFTKLGKLHAKNAFAFAIIAGNLFSDPDLATEEQDRELANLLGGNIEVQLPTYFALGQRVLPTAVIEKLTSDAGELCPNLFVLGRKVKSKTSEGFKLVAIGGRHTNVAAEAMHEYSAIYTDKDIESAKAFEEADILITSDWPAEIRDGSRAATVLAEAPEGVPGIGELCTALKPRYHLSTSSQYYEREPFFHQGEQPRSVTRFLSLAPLNNPQKQKAVYAFNLEPSAPPPQQIPDGCTASPFTSTRKRKLESQEDSFNGFRYSHGGNGNGYQERHHKRPKQQREPLKRECFFCLSNRETETHMITSIADDAYMTIAKGPLSTKSTFPGLKHPLNMLIIPLFHAPTFAAVEDGESCKKTMAEMQRYREALHTLVATKSTTGAEGEAKLGAVTWEISKGSGVHLHWQFMPVPVDMIKRSLVEAAFDVEAEHLSYPKFAKTEAEIKEAEEGDYFKVMIWSESIQKEVVLPLEKGLRFDLQFGRRVLGKLLGLENRAHWRDCIQTSEEEEQDANAFKEVFKEYDFTLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGL6</accession>
    <name>A0A9Q8PGL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09782</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766506.1">
        <property type="nucleotide sequence ID" value="XM_047908930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGL6"/>
    <dbReference type="GeneID" id="71989660"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09782"/>
    <dbReference type="OMA" id="NEQWDIA"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000008">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000014">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="865"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="685"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="694"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="892" mass="100228" checksum="6B4C2B3C0C1BC01E" modified="2023-09-13" version="1">MANAPRDSIVRVSGPDSMALPQRSTGAGEGSAQNASNVDAFGGGETPKPKKKRHRGGRNHKRKNRRQSFAVPSEATESVVDGDEQRPSLLDASRANASQQDSFYRLQGGRRGSNTSLESEALLDHREHAPFSSRSRRETIKQSFARVSQPFTRHQHRSSEASMSHQRSAMSRSKLSQGPAVMSGDDDDEQDGAQERTPLLARRSRKPDLSRNNSGYNHGYNTGVEGLRNRRTSNTSKASSRRRMEPLGMISHNNLPEEPYDVNNPPSVPGSPTIGSMDDLFIAGASSDRGRDRDAIISIDEHDDDRRYSGSPEDRRRATVAELASKDVCFPGEDDATDIGDGEETLHADRDSSQRRRRKRGKVWPDLDVLEDWSREEKEERTHQDLLRAKKISEPVMVGGRLRPVKTNWHRQIDESPFRFTYFNETLDSTIHARTISDLQDGCTFKELFRPDPPEICESSEDEDDCEDEGRTEDKMERPPMNQHRSNSDGTAKKPSVVPDLLDRPNSVMSNHKSVADSAPASGLATPKPKQKRYGNRPTFWLDVLKPTETEMKVISKAFGIHQLTSEDILMDEPREKVELFPHYYFVNYRTFEQDKDDEEYMEPINMFVLVFRDGVISFHHSESPHPANVRRRVRQLNDYMSPTADWISYAIIDDVTDVYAPLVSEIEKEVDEIDEDILYMHTTAADQAEGKVSPSQKKPAQRPKSQGKGNTQADAGAAKSEGEKITGSSGGDMLRRVGECRKKVMGLYRLLGNKADVIKGFAKRCNEQWDVAPRSEIGLYLGDIQDHIVTMTGNLSHFESLLSRAHGNYVAQINIRMNERAEQNADVLGKLTVLGTIVLPMNIITGMWGMNVWVPGQEYEGDLTWFWCITAGLLAFGVTCYFIAKRVYGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGM0</accession>
    <name>A0A9Q8PGM0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS-type transporter dbaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766420.1">
        <property type="nucleotide sequence ID" value="XM_047908199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGM0"/>
    <dbReference type="GeneID" id="71988929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09051"/>
    <dbReference type="OMA" id="PYFFIEQ"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="532"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="177"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="574" mass="61909" checksum="64B17F38A738FA8E" modified="2023-09-13" version="1">MAHKEDDFHFQMRESPLHSRDQSIASNWRGHARDESAASGFAAFHRPLTQDSHRPFGDSNFTNSSSNLVPYHERNVSDIVSPTQQAFMSRDDIRRAASPGFHPGYPGPESPTSSTNGRTWPTESPLAIPHNAAHHGDKGPSISSVVKEYLSPSPAESTHNPPPGPPGGPPPDGGTTAWLQVLAGYFLFFNTWGLINAFGVFQSYYKETLIRGQTNSSIAWIGTLTSFFLCASPISWGPIFDIGSPRLLVLFGSFSVALGIMMMSLCDKYWQLILAQGICCGLGGGALFITATSVLPSYFSKKRALAMGISASGSSLGGVMYPIVFTYVQPVLGFGWAVRIIGFIAILTLTIPCTLIKPRAKPPGARKIFDTSILLELPFEIMNLATFFGFVGQYIPYFFIEQFAAQHSLDFQFWMLIFLNVGSIPGRIIPSLIADKFFHPLKVLATTTAAATILAFCWIAIKHSTPGLIVWCFLYGFCSGAFVSLQGAAVASMTSDLRTIGTRFGINMFAGALGILIGSPVGGAIFPESWPGAQSFCGATLLLAAISIVGCWFSYQRPLVRGRGGAAKNRGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHD8</accession>
    <name>A0A9Q8PHD8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Itaconate transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766917.1">
        <property type="nucleotide sequence ID" value="XM_047910948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHD8"/>
    <dbReference type="GeneID" id="71991678"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11800"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13343" checksum="4F3E31D62D86BBCE" modified="2023-09-13" version="1">MEKQNRSDAALAEKGNAEPQQDSKTSSSSQLQDEKPKPPYCALSPHRRRFILGVVTVAGFFGPFAGNIYLPALPVFGVGETAMNATVTSFKIVFAFAPLFWTSFSDYKDVVLCISSPWRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI50</accession>
    <name>A0A9Q8PI50_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11995</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767269.1">
        <property type="nucleotide sequence ID" value="XM_047911143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI50"/>
    <dbReference type="GeneID" id="71991873"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11995"/>
    <dbReference type="OMA" id="QYVAHVE"/>
    <dbReference type="OrthoDB" id="14970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051750">
        <property type="term" value="F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000004">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000024">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149:SF1">
        <property type="entry name" value="DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="30734" checksum="4FCE7A9B0C56DDCE" modified="2023-09-13" version="1">MAPSDYSKPFINVSSPYPYVAVVELDRPKKLNSFTQQMFTDIGSVFSRLSVDPDVRAIILTAAGDRAFTAGLDVTAASGGHIGGDSNPGEDVARKAWALRRHIKEIQEPVSEIEKCEKPVICCMHGISYGAAIDISTCCDIRICSKDSRFSVREVAIGLAADVGTLTRLPHTQVPMSWIKDICLTAREFSAEEAMTMGFVSGVLEDKKALLQRAYDLAKEIADKSPIAVQGTKAVINYSRDHSVADGLDYIAVWNAAMLQSKDVKDAMLSGIQKRTPTFEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI99</accession>
    <name>A0A9Q8PI99_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11734</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767510.1">
        <property type="nucleotide sequence ID" value="XM_047910882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI99"/>
    <dbReference type="GeneID" id="71991612"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11734"/>
    <dbReference type="OMA" id="CHPHLIN"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="497"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="846"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="922"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="922"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="961"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="981"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1003"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1247" mass="140516" checksum="1D2C648274BC1DF0" modified="2023-09-13" version="1">MELEYQTEQEIEEEIAFQRILQETLDPGADDYHANLQRIEADMAHFQSQLDAMRSGSRPHSHGSSSSTHDAHPGSAQQTHDGWWQTAMDGRPQSNHSNVGVMSNPPMDNSHAMSSPRADSYQHGIGNSSGTKRARTQSAFMHPFEHASKRPTPEPSNAGTPASSDGSYDFADRPVDRMRASQAASFAAAQRRRDQQQRDEAFARQMSQSAPSSHAFASSSTRPNVQTTLNYNGSYQRPPPAQAESSSSAAHSYLPAPPTGYHHAHQPQAEHDPPHALKSEFGSAAQLQLPQRSRQHTALVDLTGSDSEDDEITEIAPTRFTPSSNNLRSLHQYTQPQTTMQMPTTMQMPGTFPAPNQANNQFVYGNGSVNNNPSTSWLQNVVGSMQGGLDELSNLVYGSNSTRPLELDSDDDDDDEVVFGGIRQIPGMYSNNQDLYNSRYDMFSNYDPGKSKEEIQAMLENIRPDEEMPAHLRVRTPEDMNVELHKYQELGLTWLQKCEEGTNKGGILADDMGLGKTIQMLSLIVTRKSQDLRCKTTLIVAPVALMRQWKQEIQNRLKLGRYQLTVFTHHGQKKAKSFHDLRAYDVVLTTYGSIASELKKMEKFRLRQRADPGARPYPAERCVFLDPEAKWYRIILDEAQCIKNRSTQTSKAASMINATYRFCVTGTPMMNNVEEFYSLLKFLRVKPYCQWEKFRLEINMPLRQQNENTRNKAMRMLQAVCKSVMLRRTKKSTFEGKPILVLPEKYVLIDNPEFDEEERTFYRSIEERTQLQFNKYLRKGTVGTQYSAILVLLLRLRQACCHPHLLKDFGVAAAADLGVDQLVELAKQLADPVVARIKESDGNFECPVCYDVTTNPAIFIPCGHDTCSECFSKIADPANAVQHGDEGRGARCPTCRGQIDAKRLTDFNSFKRVHWPEMLTEAEREAEGAHDHNESETEDDSDTEVESDGDDDGADLKDFIVDDDEEPEQADDDDETDDDLDVKPVKKESTNQEGDVAGPSSKAKGKNKDKKGKGKAKKKGKKIKSTVTLAELKKQATRNKAAKKKYLRRLRKDWQSSAKIDKTMEILSEIMDDKEGEQVLIFSQWTSLLDLLEVPIDQAGIGYRRYDGSMSAAMRGDAVDDFRDPRKNVRVMLVSLKAGNAGLNLNMASQVIILDPFWNPYIEEQAIDRAHRLGQRREVKVHRLLIKDTVEDRIIALQEKKRALISEALDEQQAAQLGRLGVQELAYLFGVTHDPSQHINYTAQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIB1</accession>
    <name>A0A9Q8PIB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-rhamnose-1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767412.1">
        <property type="nucleotide sequence ID" value="XM_047911169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIB1"/>
    <dbReference type="GeneID" id="71991899"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12021"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019301">
        <property type="term" value="P:rhamnose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000417">
        <property type="entry name" value="Glucose 1-dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0684">Rhamnose metabolism</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="27045" checksum="3E154EA3688F43CE" modified="2023-09-13" version="1">MAQLLPGKVAAITGAVTGIGKAIAIDYLKHGALVAVNYYPDDKSKQQFEDLKQEAGAGDKLIGVAGDITEPATGQELVEQAVERFGKLDIFVSNAGVCQFADFLTISPDLVNHTISTNLNGAFFAVQAAAQQMAKQEPQGGSIIGISSISALVGGAGQTHYTPTKAGVLSLMQSTACALGKHGIRCNALLPGTIRTQLNDEDLADEDKRKYMEARIPLGRLGRTKDLAGPAVFLASDLSEYVTGAQLLVDGGLFVNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF1</accession>
    <name>A0A9Q8PIF1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peroxin-10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_12213</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767363.1">
        <property type="nucleotide sequence ID" value="XM_047911361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIF1"/>
    <dbReference type="GeneID" id="71992091"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12213"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000395">
        <property type="entry name" value="Putative Peroxisome biosynthesis protein (Peroxin-10)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO22997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="395" mass="44546" checksum="AFA7CE04A053F538" modified="2023-09-13" version="1">MSDHVHDRGRSLTTESSSPTFNYPWAAAPDIIRSNQKDAYFQSVLLTQLSSVIRSLYGTRSEHKWSNEASVFTELLYLGLTTFLGNRTLGEEYTDVIQIEDDTHRLPSLARRSGYILSSVLLPYILNRFLPLFRKRLRSKLEVTLTKAHRRRVSSPTRQKAPPTKSAQLQEYILKNLDSITSPAPFYAASLAIFYFSGAYYQLSKRLFGLRYIFTRKLTESDQRAGYEVLGVLLIVQMVVQGYLHLQSTYQTVQLAPGPSDPASSQLLNGGSAIIDEGIELGVENHFNTPLLFEAHSQGNDPEVIKQRVAKVTHTPMLKGGGHRYDLKDGEVMQWIEGSQSRKCTLCLEAMKDPSVTTCGHVFCWTCVTDWLREQPMCPLCRQGALVQHVLPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIK5</accession>
    <name>A0A9Q8PIK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="13">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_12022</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="13">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="13"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767411.1">
        <property type="nucleotide sequence ID" value="XM_047911170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIK5"/>
    <dbReference type="GeneID" id="71991900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12022"/>
    <dbReference type="OMA" id="FRAGEIW"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="229"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="470"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="650"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="710"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO23045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="720" mass="77770" checksum="20C2A0D6CC0A9692" modified="2023-09-13" version="1">MDPFQLLSRSTKLSKGGLLRPQHSTPSSGDLTRPQLSSNGTGEQGGITNSSRKRKRTQERSHESNELDFFGGDGHKTVRGPSNEGGSKKHGSNNDISDDNEEEVLEHVTGTLRSGSSGSTVMSENERKEILQKHKLKVTWIKAAPSKKVKRDGVEKKKAKAGKTDKISVHPRPLRSFAELKSEYGLSTRLASNIDDQGYREPTEVQMAALALLMDQDNEWLPAAEALRSSFPNGKTSLLTVAPTGSGKTLAFMIPLIHSIGKARHKTSEDARRKISAIILAPTKELASQISNEGRKLAQGTGVRISQVRKGMKLATQTVEPSEEQDEAQGGSETVVKSDILVATPGILASAVKDASEVGSAVLSDIQHLVLDEADVLLDPLFRDQTLSIWNSLPQGSMHVSLWSATMGSNIEELARSTIDTRLARISQEGGSDLVAAPLVRLVVGLKDSAVPNVQHRLVYAASEQGKLMGLRQLLHPAATSRDVGPPLLPPFLVFTQTIERAVALHSELVYDIPAEAGGISRIAVLHSDLSDTARDKVMTGFRKGEIWVLITTDLLSRGVDFRGVNGVVNYDIPTSSAAYVHRVGRTGRAGREGGVAVTLYSKEDIPFLKPIANLVAAAHRLKGIPDADMTGGVQPWLLDALPTLSKKAKQDLKKRGVESRTTRGAQRDPKAARKSRISTKPGFLRKEENKKKGAIMGSRNRQEANASDAGDESDFGGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIN1</accession>
    <name>A0A9Q8PIN1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767441.1">
        <property type="nucleotide sequence ID" value="XM_047911192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIN1"/>
    <dbReference type="GeneID" id="71991922"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12044"/>
    <dbReference type="OMA" id="FEACCNA"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="30414" checksum="3275A712ACC54EF5" modified="2023-09-13" version="1">MTEKGVHIEGVDYYTLTERPQSGNGHPERHVLLAHALMSNLHMYDQTVKALTNAGFTTIRFDHIGHNNTPAPSSNASYHMDDLTRHMHQLVEATTGQKHLHAVIGCSIGGVLALRYAMLYPGNVEKVISIAAPGIVTPEPSKALWSQRIEQFEEDSRSGGSVLCHATVNRWFPGERAEDDSVRAEALSHVKTCSLAGYKMLADTIRDYDYGDEVRGIRDVKCLVVAGSEDSAVSPGLLKDVASRIVGAEFVRMEGAGHLPPMHKVEELNGMMLAFLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIV4</accession>
    <name>A0A9Q8PIV4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767742.1">
        <property type="nucleotide sequence ID" value="XM_047911969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIV4"/>
    <dbReference type="GeneID" id="71992699"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12821"/>
    <dbReference type="OrthoDB" id="5273928at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="378" mass="43756" checksum="8FC1152F2F7FD0EE" modified="2023-09-13" version="1">MPFDTENGQTFHETTMRVRRRRCKCLQGMFRRGVQPPSIEERHVSRSLQDMAVRTLLRNLGLLNGDALRPLPTHLLARLWSTIKYYLLDSVHLWRLFASIGGLELGSKRWNQKQIDCRRHGLKDSIKWATSTSIQWMTNLTVSELDCSVDEMMYIQQMPNLRNLVIQAGEYLKSHLSDSILREWAHSSKRYGTLSHLQTMFIARQNITSWCLQYLNHFPSLDTFCAYRCNYGARDTVSKIADQEGWSLDKRGGTFHATVKRLSKHCQPGYKLIHLGSSYTEHRQLTKKSSINSLPHLQLNFGNAGKKPKPSMLHFSIADPKFFCFERNWEHRLSAAGVTTVDMEQGPAVHQEKPAKRRRREVKASKSISLPQHIFFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ84</accession>
    <name>A0A9Q8PJ84_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767871.1">
        <property type="nucleotide sequence ID" value="XM_047912347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ84"/>
    <dbReference type="GeneID" id="71993077"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13199"/>
    <dbReference type="OMA" id="ELACMRN"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040542776" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="33"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="394"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="525" mass="56322" checksum="D0DA4CF802DA79C4" modified="2023-09-13" version="1">MIVLTALSAYLAIASAGSPRRHHGGYKGSAQDQLTVSTSSGHVHGKIDPELPNVRQFLGVPFAQPPVKDLRWSAPQPLSQPDAHIEATELPPSCNQFLSSTLGFSTAEILEFNLQGLNKTGATSEDCLTASVWAPVNQQHGYGSRKGKKGEEALPVLIYIYGGSFSTGGQDVPYQIPAQWVDRTPDHIVVSFNYRVNIFGFPGAEGLDDQNVGLLDQRLAVEWVRENIAAFGGDPEQMIIFGQSAGAASVDYYNHAYPENPIVKGLIMESGTALIPIGGDPTGMSFTYVATQLGYTGSANDSAAVLSYMRSLPADEIENFVANHSNSGSSPGLSFGPTPDEKSVFANYTERALAGHQAKIPAIIGTNAQDGVTLAPYNPNGTNLTIADAAYLRTFLCPATQTIHLRQETGRLTYSYRYAGNFSNISPKPWIGAYHSAELPLLFGTHPNYRGESTELEYQTSCAMQDAWVAFAKDPESGLEGENWDVYERLGSQEVREFGAGVAAQDVSVAPLESMCNGAVPAEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ94</accession>
    <name>A0A9Q8PJ94_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767886.1">
        <property type="nucleotide sequence ID" value="XM_047912134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ94"/>
    <dbReference type="GeneID" id="71992864"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12986"/>
    <dbReference type="OrthoDB" id="10421126at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15363" checksum="47579AB347A0CAEF" modified="2023-09-13" version="1">MMIQLVAAAPNWTRALARAGVARQRPYDPFCQERALREGPGELLGEVLMNMLEDEEPAMSNRASVDFWARVTEHRRELMRYIVEKRTGGELLLWAKDDAPLSDDPIVGAMNAALWANSKVDPQSLPIWVSVWWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJM7</accession>
    <name>A0A9Q8PJM7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768081.1">
        <property type="nucleotide sequence ID" value="XM_047911750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJM7"/>
    <dbReference type="GeneID" id="71992480"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12602"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="440" mass="48542" checksum="26D6C0A613322446" modified="2023-09-13" version="1">MADTSSPYLDTAAFLSDDFNPSAYANKLVLDTNNPTDTPLDLSTPLSKVLFDVQEVDTHIDTLTTQNALPIVSHARERNDAATRVLETVEEQVNTLSESYKRLEREVGERYEAAEQVRLAAENMVKTLRLGRAVQRVVQLGRRLEEEMDMVSSPASKERVSGHRAMVPAARTVLELRSVFTGEEGSEVGRVNAAQSVRQDLGTPSERSLITRAQGVVREFSMSSLLNAGGNEKTFAQAEETKERAKSAMQTLWLLSPMKKDTTVVTFDPSLLLQALQSYLQTAITSSVAAIARALATLPTLDRALLETSARCQNIIALESLLENIKPPTHPLLQSSTSTNTTIDQNFLQPLLRHLDTSSLPSFFWRSMASQMTSRVQEFMSRGGVSARTLRTNKDRVRDAIREGVDRGYRGTRDKGGKTQASWEREAAVMVSSVVGPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJW2</accession>
    <name>A0A9Q8PJW2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768189.1">
        <property type="nucleotide sequence ID" value="XM_047912079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJW2"/>
    <dbReference type="GeneID" id="71992809"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12931"/>
    <dbReference type="OMA" id="MGPYPMS"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="709"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="847" mass="92254" checksum="C6F82F9B6F12195C" modified="2023-09-13" version="1">MAPAVAPPTTRLDPISITVYYAADKQSNTAIAYRTEDLERQRREPAYVPDCFDITTPKKESVDPAQDFEEASLKRQLCDFLGYQEHHEPTKAPKLHAHSVAPRNYGYAPAQRPPPAPPAAHMRHHNPELTPAFAEAAKQQATCLPQAFNNDRYRNTATSLAPPNPAMVTRQLQPPSTDGHAQSNGQILANYYARQRPVSESAYSAATKAAHEARQASQITNHGGWSIQGNARASRFQPTPQPPLASPNMAPYAMGGNNFALHRSPSLAAVQQHNTLTRPQNTSAPMGTYPMSGNILTPHRSPSLAAVQQHNIQTRPQSTSAPMGPYPMSGNTFTPHRSPSLAAVQQHNIQARPQSTSAPMGPYPMSGNAFAPQLSPSMAAMQQYSAQTRPQSITPPKGVNSMGGSNFAPHRSPSMATVQQHSAQTPPQSITSSKGLNSTGSGSWSSHPRLATTPVLTPSPGANASPRAGASPLGGNTTQWRGAQMPPRRIDSPQQSWLHNASAQAMQPHAWAKPPLSPPKPGQSQPIHVSADGRYYLPDSTERRFLQPVEPGHAERTPDQYQQAQRQLQQRQESTENWRKKQQEMAQMAANMQAKILAQDDTLYRQANSLNSQPRRQISDGKMSVSALARQYNVDVNATASARPPLPASSDPGGHRVVVQGRRHYAAPEVMHRRAPSGDAPAPSQKQAQGQRHYTAPEVVHGRAPSGNATTPSQQQATQPPYSTPASGAIRNGSFRDAYLNELLPPAQSHGQEVQVFIGLSETQILLLLRLLPEVQVQIKSMAPADRRRWLQQFYAIHQAKIDPMVQLPPNGSQPRQQQSVQLPLNNGQPRQQPTVPAREQPPSPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK00</accession>
    <name>A0A9Q8PK00_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor TFIIB cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768261.1">
        <property type="nucleotide sequence ID" value="XM_047911774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK00"/>
    <dbReference type="GeneID" id="71992504"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12626"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="27875" checksum="CF524EEEF18C9DFA" modified="2023-09-13" version="1">MCQISQFEYKCNSSACKTPERTDTEINVLRYCDWYTNRQPCTGMKASMSDEHSHERKHTATKTVRIKKCRLCQPAIRPIEQGIWIGLLLLTVVSISYCGSSSSDVFNCAWCLAMLHALLLTFPAAYRRPQEIETVQRSIEISPTPGKTCAEYCSKLQTSPRTTHVAVDLAAKTIGKEQVGQQRLVLIAASIYMASHLMSEPEDAHKIQEVVAVDLWQAYQKLLDRADELVTGELVCHGADVSKLPRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK57</accession>
    <name>A0A9Q8PK57_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768268.1">
        <property type="nucleotide sequence ID" value="XM_047912196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK57"/>
    <dbReference type="GeneID" id="71992926"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13048"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="125" mass="13999" checksum="88CAB8CEF44AA852" modified="2023-09-13" version="1">MPSEAATAAILGGFAVASVFAGLLFAKLLYYCIETRPEKARQRREQKDLEAQRVARQRTVWSSRAGNLNTVTGHQKTTSTYQPATVEAQRQSIEVAREAAEKLAKEVSGEDEGKFRRWVWKVTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL72</accession>
    <name>A0A9Q8PL72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GRIP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768889.1">
        <property type="nucleotide sequence ID" value="XM_047912988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL72"/>
    <dbReference type="GeneID" id="71993718"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13840"/>
    <dbReference type="OrthoDB" id="425925at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019459">
        <property type="entry name" value="GRAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921">
        <property type="entry name" value="MYOSIN HEAVY CHAIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921:SF2">
        <property type="entry name" value="THYROID RECEPTOR-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10375">
        <property type="entry name" value="GRAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="6">
        <location>
            <begin position="446"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="554"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="298"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="520"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="69171" checksum="1C08DB3A9A5784EC" modified="2023-09-13" version="1">MSAVNAQADASKSASKKKKKSKKKANGQPTAGSTSVGHNGAKEIADEDGDEDEDEESSTHAQAIMPSKGSAEDSSHTPSTPTEPASATEQPLPVRIGAQWPKTSNGAKHEPEEDEDEEEDESARPSRQPSISGDTTARLDAMQQERDSLRAEVTQLRKSLESLQDAQGDELSTVKNELQQTREGKEHAETQYKNLLGKVNTIRSQLGERLKSDAAELEQCRERIEELETSNRTAREENQRLQENISKLNTDMESQATEIESLRSRTNLSTSNWAKERDDMVQKEAYLREEYEIAKQAMQDWEILATEERSRREALEERMQELEEQLNAQREAFERAQGEANTQSSTVDGLQRALRDLQEERKRELREMVEQSQTQLDALRAQTKTAEETAAEFKAQLETTQRELERTAPFEKEVKEKNLLIGKLRHEAVILNDHLTKALRFLKRGKPEDNVDRQIVTNHFLHFLALDRSDPKKFQILQLIAALLGWDEQQREQAGLLRQGSGFASASGSLRVPMSPFRRTPSTPSLSSDFSPLSPTGEQGRESLAELWSDFLEREAEQGGGSSRRQSIQSNRSPSIGVMGPTSERGGPMSSRPDLKRKESQTSQASGHVRPESSASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM91</accession>
    <name>A0A9Q8PM91_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytoene desaturase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phytoene desaturase (3,4-didehydrolycopene-forming)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_14250</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769580.1">
        <property type="nucleotide sequence ID" value="XM_047913398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM91"/>
    <dbReference type="GeneID" id="71994128"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14250"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000171">
        <property type="entry name" value="zeta-carotene-forming phytoene desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF1">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="10">
        <location>
            <begin position="69"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="449"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="453"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO25214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="66435" checksum="199542594D686ED1" modified="2023-09-13" version="1">MVFASLSFPPAPLPCIVDLACQDLPPRFHHHFHNATTDNYHIHGAYRISQMAPNATPQKTALIIGAGVGGVSTAARLAHAGFRVTVLEKNSFTGGRCSLLYADGHRFDQGPSLLLLPDLFRRTFAELGTSLQEEGVELVKCEPNYIVHFHDGEKFRLSSDLSVMKGEVERWEGKSGYERYLGFLGEAHRHYELSVREVLLRNFYGVVSMLRPEFLRHLIELHPFESIWTRASKYFWTERLRRVFTFGSMYMGMSPFDAPGTYSLLQYTELAEGIWYPVGGFHKVVEALVGVGERKGVEFRMSTPVRRILLDASGSKTEGVELESGEVLKADVVVNNSDLVYAYNNLLPQSESAKKAAYAEALEKRPGSCSSISFYWALDRKVPELEAHNIFLADEYRESFDSIFQKHLIPDEPSFYVNVPSRVDPTAAPEGKDTVVVLVPVGHLVDDERSRYENTSNGTATSNGHLKDASPSNQTGFTPTSTQNWPSMIALARKTILTTIATRTGVDLTPLISTELTNDPTTWRSRFNLDKGAILGLSHSFFNVLCFRPSTKARRAGPLDDLTRGLGPLGTVVQVVGDAFRGEGRFSLLALTPQYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMH4</accession>
    <name>A0A9Q8PMH4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769626.1">
        <property type="nucleotide sequence ID" value="XM_047913722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMH4"/>
    <dbReference type="GeneID" id="71994452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14574"/>
    <dbReference type="OrthoDB" id="3365636at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
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</entry>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="8">
        <location>
            <begin position="66"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="224"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="763"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="768"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="785" mass="89643" checksum="CB5F5906AA9D97D5" modified="2023-09-13" version="1">MSEQDDTGTPLVIIKKKTTASADDLDVQLQPIKKRSTFPRTISELVTTQLVPGDMAKSHALSTNMDVDYVIVFRSPPSEKVKAAASFEQLCQRLAQVGLAIETRNGKEDSLLAFTRVASAEHMYAEIYRSRVKDWIHGVRAGEPATDVRASLEQDPLTDAERLRIIYQLITNYEQDGGAGIRPKSREWPYVESVFALHDHTFNKQLMTKWATQWQIQTEDLDNIRDRFGEKVAFYFAFEQTYFTFLLAPAGFGFFAWLVLGSFSPLYAIFSCLWATVFIEWWKHKEGDLAIRWGVRGVGNIENKRHDFRPTKEVEDPATGEKQLIFPWEDRLKRQLLQIPFAIAAVVVLGSLILLCFAIEIFIGEVYTGPGKSILTFTPTVILTTCLPLLSGVMTNLAKRLNDFENYETDSKYDRQHTGKLLVLNFITSYMGIMLTAFVYVPFGSVLVPYLDVFSRLFAAKQHEHMDEKGTKPGHFTINPDRLRKQVIYFAVTAQLVNFAMEVVVPYLKRQGFLKIKEMTAKRVGAALQSPPSADMDDNPEEKEFLDRVRSEAELPAYDVYEDLREMIIQFGYLSLFSVVWPLVPVSYLVNNWFELRADAVKICIEMQRPTPWRADTIGPWLDALSFLTWMGSITTPALAYMFSNDGIGPDGRPHDIKAWGLLLSIFFSEHLYLLVHGAVANAISKIDSPGKQKERRDRYETRQRLVQDSLAKLPQTPNMGIYEEKPITRESLEEEARQGSLKTSTALERFWNRQRNWRESAQVGKGLIEHKMDTNQSEKSKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USD5</accession>
    <name>A0A9Q8USD5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765032.1">
        <property type="nucleotide sequence ID" value="XM_047910598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USD5"/>
    <dbReference type="GeneID" id="71991328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11450"/>
    <dbReference type="OrthoDB" id="3645966at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="25371" checksum="3C008DA0184FD24D" modified="2023-09-13" version="1">MSHFNKAVAEKARLDAIAASFDNATTTPDLVVLCNHRRILCHKNILTGQSKWFQKACDGKKACDGKFKESQSDTIGIHEEDDKIIYAMLEFCYRFEYIGAGCISSLGASQKDAPAFHAHMFAAGEKYFVQGLKDLATDHFIKSVKAASDDDLAAAIRAVYTEVSDPDKILQAVVTEAVLGKATTLLSGASTVLNDLLDALPAFGGDMTRAFAKSKSSRTPSKPQRHPPQTKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT12</accession>
    <name>A0A9Q8UT12_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765795.1">
        <property type="nucleotide sequence ID" value="XM_047908282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT12"/>
    <dbReference type="GeneID" id="71989012"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09134"/>
    <dbReference type="OMA" id="GWVGYQI"/>
    <dbReference type="OrthoDB" id="4083871at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077:SF1">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="15888" checksum="2B6EE92A80C929AC" modified="2023-09-13" version="1">MAKLANLVPLVILFLVVAVGGFIGYSIYTWSNELQERGKKKMEKKNMSFTKEGGLRVGVKEVKDEKYADKTQNVLVNVWNNAELPNYKSSLGWNSTQGKNGASTPKSGTSSPRPSGSRSNTGNASGAHVASGEQRRAAQSPSTPGGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTI0</accession>
    <name>A0A9Q8UTI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amine oxidase</fullName>
            <ecNumber evidence="11">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09617</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="11">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="10">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10 11">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="11"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766186.1">
        <property type="nucleotide sequence ID" value="XM_047908765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTI0"/>
    <dbReference type="GeneID" id="71989495"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09617"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF91">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="12">
        <location>
            <begin position="248"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="9">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="10">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="698" mass="77646" checksum="C6FEF95489C98237" modified="2023-09-13" version="1">MAPHPLQQLSVQETKQAKAILISEHDKDEVLIIREIFLQEPAKAELQKFLALEHSNSLTQSSPRPSRQGLCQYDVVGSDKVPYFHEAVIDLNKKARVKHEVIGKDQHAPLKLAEFDHLVDAVQASKEIQDAIAEFDIPEGFEVLVEPWPYGGPDLDEQNDRYFQGLIFAVDKRNNNADSNFYAFPLPLIPVMNAQTKEIIRIDRLATGGKGDSMTGQTHAKGVLDHCRPAEYVPELLPDGVRKDLKALNVVQPDGPSFTVQDDSLIEWQKWRFRVTFNPREGAVIHDVWYDGRSMFYRLAVSEMTVPYADARAPFQRKQAFDFGDGGAGNCSNNLSLGCDCLGVIKYFDGVLISGDSEVKAAPNVICLHEQDNGIGWKHTNWRTGRAVVTRNRELVVQFIITLANYEYIFAYKFNQSGGIDIETRATGIVSCVNIDPGKQSDYGNVVSPGVLAQNHQHIFAVRIDPAIDGHANTVVQEESLPVPMNPDTNPRGNYYEVKRTPITKSSWADAEPKNNRVFKIINENKKNPISGKPVGFKLVPPPTQLLLASPDSVQAQRATFATHHLWVTKYKDDELYAAGRYTLQSRKELGGVADAVARNENVENEDVVVWSVFGLTHNPRVEDWPVMPVEMHQINLRPADFFEANPSIDVPSGRNAESKLVVGNGGTDAQQQNGNGCYNGANGHAQEEVNGVTNIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTS3</accession>
    <name>A0A9Q8UTS3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766486.1">
        <property type="nucleotide sequence ID" value="XM_047908665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTS3"/>
    <dbReference type="GeneID" id="71989395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09517"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="25291" checksum="EDCB313AF33B5605" modified="2023-09-13" version="1">MAKIVHLRLAEQIWDTGDETDAGVDIILGPIKLRAAEYTDVNTMAAATTLFSGQARPAVLSTDDTLLNQDNWQLRDLAFTYIHTGGTIVIIPMVGSNGVYIEEFVVKLGLPWVEKQIGRRDFSVNSAFRRFSVSSIRGYSCGSKAMHLEDVAREDSLLISPRNWVYRSDVPPGGHELDRFRDDEEEAAAKVEKHYVAAALAGVGQGRVGYVAECFGDADAVNVVLGMLGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTT0</accession>
    <name>A0A9Q8UTT0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">[Acyl-carrier-protein] phosphodiesterase PptH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766562.1">
        <property type="nucleotide sequence ID" value="XM_047908790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTT0"/>
    <dbReference type="GeneID" id="71989520"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09642"/>
    <dbReference type="OMA" id="NHWPLRE"/>
    <dbReference type="OrthoDB" id="550558at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052963">
        <property type="entry name" value="Pantetheine_PDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36492:SF2">
        <property type="entry name" value="[ACYL-CARRIER-PROTEIN] PHOSPHODIESTERASE PPTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="35767" checksum="E9A51D66BA2A9FED" modified="2023-09-13" version="1">MQLWAIADIHLSFKSNREEWAKLQHKKDDGLILAGDVGESLDHLKEAFRKATRRFKHVFWVPGNHELYTSSSPSISDKEKKLKGEAKYKACIKVARHYGVLTPEDDYMTWPYEGADGSQERALICPIFTLYDYSFRPEHVTREKALEWALEEGIQATDEKLLHPDPYATRDAWCTRLVSEAEVKLEKAAASGLPLVIINHWPLREDTVFIPRVPRFSLWCGTKETNDWHTRFNAKVIVTGHLHVRRTDWIDGVRFEEVSLGYPRQWQDAKNVGNDVNSMLREILPGPPSPPPGQVPPTLFRRLGWGEPICM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUC2</accession>
    <name>A0A9Q8UUC2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767147.1">
        <property type="nucleotide sequence ID" value="XM_047911326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUC2"/>
    <dbReference type="GeneID" id="71992056"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12178"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="22732" checksum="FB313E824BA165D2" modified="2023-09-13" version="1">MEVLLGITGKDFTIVAASKAAMRGASILKASDDKTRQLNKHTLMAFSGEAGDTIQFAEYIQANIQLYSMRNSTDLTPYEAASFVRSELAKSLRSRSPYSVNLLLGGFDDISNTPQLYWIDYLASCAPLPYAAHGYAQYYCLSILDKHHHPDISFEQGMKILRMCTDELKRRLPIDFKGVLVKVVTKDGIRVEPYEDDKQVLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUE0</accession>
    <name>A0A9Q8UUE0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767058.1">
        <property type="nucleotide sequence ID" value="XM_047911220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUE0"/>
    <dbReference type="GeneID" id="71991950"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12072"/>
    <dbReference type="OrthoDB" id="5230484at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7624" evidence="2">
        <location>
            <begin position="597"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="723" mass="80028" checksum="1C877F44E29DEC60" modified="2023-09-13" version="1">MALKSPLMPSPTGGGLDSAFSPYSDSPNSPARFNNTFQNGDHTRSNRSSGTNDNLAPPASPYPQQIEPSPVDSTTSNGTESTEIDEDAQEEGVKSPGLETNSEAFDVQSPDLEITSPESAKSDIPHKLDTHLPPRHRSDSADNDPQSVIHAPSGFHDFKDGATTHESPVELQHTARVASPSTPEAAVVGPGDKKPVTSPVNTNVPQYTDRSTPRAQTRQELDDDYKRRSRRTSSLEDIPEALDKDTDDDRNTSHEDERPNTAELVGEGSMQQAMDVLNQVEDEVAALRTALSECWTLCNTLANLSSSHRQRTFKFSGKTEVQEQAWRSCWKLCQQLYEHRDDDHTAQVLPTLELCRDFCQSLFDARQKMDEASDSVLRVSFELNNHLYNTHDRELPDAFNERTLDFYITLCHRLMKQRTSLPQETDSLLRACWQLAENLFNLRQSSREGRSPDEELLGSAVQACWELCDLFREGWTQIRPERATPRPNQTTFGSQSSFKSGSTRSAGRSTSSTISNRKYHEAQTFPPETPVTVFDDASTANSSPDSISVPNILVLGPASTGSNNSVRGAPHHERWSSNASVLSDYSESAASSQRSSSTATAGAEEAQLGRLRCLLLKAGMTTGYSRGSGQQLPIYVKALPDTAFGTLPWQMKVLTFYKKLVTNDKSMYSVHQVPSRRLGAAGIAKAVRWLGNSEQWAWMRDLFRIVFGFGIDEADRRGGSFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUN3</accession>
    <name>A0A9Q8UUN3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767343.1">
        <property type="nucleotide sequence ID" value="XM_047910958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUN3"/>
    <dbReference type="GeneID" id="71991688"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11810"/>
    <dbReference type="OrthoDB" id="6224010at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF5">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="150" mass="17478" checksum="79DDB48A165BEC39" modified="2023-09-13" version="1">MAAVMATPEITTAKGTAPNPSRNPLPLSASQESQVRELYYKRVRQKCADEVRDFAACCTQRTFTATFMCRSEQKTMNACMKIYATQEEQDAARAEWFATMDQRREEREKKELKRIKDEKFWKEWWAKDKKGVPSTEGRDMKGRHIDDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVA7</accession>
    <name>A0A9Q8UVA7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768076.1">
        <property type="nucleotide sequence ID" value="XM_047912019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVA7"/>
    <dbReference type="GeneID" id="71992749"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12871"/>
    <dbReference type="OrthoDB" id="4159154at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF7">
        <property type="entry name" value="SUR7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="424" mass="45028" checksum="13D324FDCF86D219" modified="2023-09-13" version="1">MFPLLAKIFLPKIANKVFGKAAAAAGVPIPQKQPGRPLTITIPMVFSALLFIPAVVLVVLCFFAGHKPGFLDEYAVYTVNVFRIGENILTGMNQQIRGVNITKRSEASLPVTLPVALFARDDDDEDETTSSKAQPSTTSTKPTSARTTPTAKPTATPAPSKPAAAAGPAQSAVIQQVNKAFGAVVDDFALDDFYDFHVLGRCYGSYVAKNGSASANVTDGTGATVLQDKLEKKVTACEKKASALTLAAVAYGFAMICTGLAFVASIVSSIYYRKKFVLVTLGITCLALLAQLLSSAAAHAIANSATGLVDFVGHPVGIDGSAGKKFITLTWAATIILAILAGLWGMLLFFGRNEPAFNGQKAERLESVQHEQYNLSSWPQHPHASHAPTARSASVYSRRTDGFEHTPTYPTRAYNEGRAPDGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVT4</accession>
    <name>A0A9Q8UVT4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13544</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
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    </reference>
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        <reaction evidence="5">
            <text>L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.4"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 10">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO24250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047912692.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UVT4"/>
    <dbReference type="GeneID" id="71993422"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13544"/>
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    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0004354">
        <property type="term" value="F:glutamate dehydrogenase (NADP+) activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutamate dehydrogenase"/>
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    <dbReference type="FunFam" id="1.10.285.10:FF:000003">
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        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
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        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
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        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
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    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006929">
        <property type="entry name" value="PRK09414.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="194"/>
            <end position="458"/>
        </location>
    </feature>
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        <location>
            <position position="118"/>
        </location>
    </feature>
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        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="8">
        <location>
            <position position="106"/>
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        <ligand>
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        </ligand>
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        </location>
        <ligand>
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        <location>
            <position position="201"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="site" description="Important for catalysis" evidence="9">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
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            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="463" mass="50323" checksum="A7A9EBAC765C40B7" modified="2023-09-13" version="1">MAGVSGPNLSEPEFEQAYKELASTLESSKLYEKNPEYKKALKIASIPERVIQFRVTWEDDKGEVQVNRGFRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLNMGGGKGGADFDPKGKSDNEIRKFCVAFMRELSKHIGADTDVPAGDIGVSPREIGWMFGTYRAERNRWEGVLTGKGGNWGGSLIRPEATGFGLVYYVQHMIQYATGGKESFKGKRVAISGSGNVAQYAALKAIELGATIVSLSDSKGAIIATDDKGITADEINYIADLKVKRKALTELSESPEHKNKFKYIEGARPWVHVGKVDVALPSATQNEISGEEAQKLVEAGCKYIAEGSNMGSTQDAIDVFEKVRKEKKGDGIWYGPGKAANAGGVAVSGLEMAQNSQRLKWTSEEVDNKLKGIMEACFQNCLETAKEYVPAAEGELPSLVAGANIAGAIKVFSAMRDQGDWWSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWU5</accession>
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    </protein>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="656" mass="69712" checksum="3D39CE60F9782CDE" modified="2023-09-13" version="1">MPMFAPSLRTHTTDIQGCRPHSLTLSSIAVLSSAFVSLVYPNARRVDNNSFQPIRALESITEPASSRDCFILALVTPFHLRHLHLQLEHEPHTQPHKNFRHPPNNSSHLNPKHHTRLVTALHDRPPPTTTTSYTHPQTASMLSAMTAVKAAAILAFPLAYAADLSAYEGYSAECITCNSWMLTSASNPSYFEGDNPLVAVCAAGNDKTFRPCDKLCIDKFGHSLRQNKCAGSVQNGGHKQARQTENVIGNYEGYSEECTQCYSNALPSAFQPPYTYGDNPLTAVCASGNDQFFRPCDQLCIDQYGHTFRQSKCAGSGHGLMQARQAENVFSGYEGYSEDCTSCFSNLLSSAYSPAYTAGDNPLTAVCASGNNDIFKVCDAKCVDEYGHTFRQNKCAGSVKAPPSKRDSSCEICWKTRSSELGCNTPFVIAGHEFELAGCMCQPGKIDSFKQCDAQCNQGGMFPSYACAVLGLSKRHEDETTTSSSTSVSTSTTFETTTKTVDPSTTSCNSTTSLLVAPAATDVPCPPGYKFCYTTAVAGSCVLSELPCDGTPAATTTGKPCPSGYKSCYTTAWSGLCILPELPCPGTPNPLGPGPVSANSTIPFASGTIGLTHPTANATTGQPSEAPPTYNNGASGLGGFGAAAFSVVAVLMGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXM2</accession>
    <name>A0A1P8YXM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp15</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp15</name>
        <name evidence="3" type="ORF">CLAFUR5_07043</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943091">
        <property type="protein sequence ID" value="AQA29262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="UJO18797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573434" evidence="1">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14271" checksum="186BA05A0971F2B8" modified="2017-04-12" version="1">MAYLRFFIAATMLPASVLGAAEYAATFSRCPGTTDGVGRTWLPDDNRCAWLAFDAGPYDVGVHSPSQPLITYNSYCCLWDHGISACYYNTRYHGDINSKAECAQDTAPCAFFERHPGVDHGTVSSQARGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXU1</accession>
    <name>A0A1P8YXU1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="6">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11901</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">0WU</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="6"/>
    <dbReference type="EMBL" id="KX943171">
        <property type="protein sequence ID" value="AQA29342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767550.1">
        <property type="nucleotide sequence ID" value="XM_047911049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXU1"/>
    <dbReference type="GeneID" id="71991779"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11901"/>
    <dbReference type="OMA" id="LNEPALY"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF8">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671819" description="glucan 1,3-beta-glucosidase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="93"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQA29342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="418" mass="46751" checksum="A90BBDB593726EAB" modified="2017-04-12" version="1">MLFKGAVVALCAAFATAAPSHDKRGPSGFPWGKDKVRGVNIGGWLLLEPWITPSIFQQFDQSRGIMDEYTLGQALGAQQAREQVLQKHWDTWCTWADFKKIADSGFNAVRIPFGYWAFDSSDSPFPSGSAPYLDAAIDWARSTGLKVMLDLHGAPGSQNCFDNSGQKCDTPKWTTGNTVAKTLRVLKTVQDKYGASSYDDVIMGIQLLNEPLTPVLDLNVVKQFTRDGYGQQRDSSQSRVVVFHDGFQQVNKYNGFLTPSDNNAQNVVVDHHEYQVFSPELVAMKPWEHRQYICNNAIVYSGGDKWTFVGEWSGAMTDCAAALNGYGTGARYDGTFPGSSYVGSCQNINFMETWDQQFRDDTRGYIEGQMESFERNTEGWFFWNFKTEGAPEWDAFRLIDAGIFPQPLTDRKFGAICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4W5</accession>
    <name>A0A9Q8L4W5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755237.1">
        <property type="nucleotide sequence ID" value="XM_047901022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4W5"/>
    <dbReference type="GeneID" id="71981752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01874"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="59" mass="6010" checksum="AD4BF14BBFB0F17C" modified="2023-09-13" version="1">MIAALREARVARILYCHSKSRINVGVVGAGIGGLMASIAIARAGGSVTVLEAAFQLGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L529</accession>
    <name>A0A9Q8L529_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">CLAFUR5_00654</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L529"/>
    <dbReference type="OrthoDB" id="2160599at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="293"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="405" mass="43681" checksum="FBB8D5065D445E84" modified="2023-09-13" version="1">MSSIDGERSPKRQRTSGSYSPASPPITAETKTAQRPFTPPPSVRMSPSWQSQSQIQHTSGSSPSPPSTAGFQSHMAGRGVGSEGGGESGRETPASDGYPDTRRDLYGDAEMSDRREGVEGNDVTGESEHRRTDHERQRSGQNTVMKMPASAPPLHKLHTTPIAPSRPHPSQNLIQLYGLQRIQTSVARRDPVTGEKINKLRKSYENKVKSLGFAGRNKAQANQNELQGLLDPLWDQEIQPGVSLWQSQTRDSGKQLGTPEAESDLSSKLDAAFQLLPGRLPAQLHKEWQNMLGLDDQSTGGGTKANTTPAVKPAIGSATARTAPTVSARASAPASPGNVARPERSGKKRSYQDSSFEGYDQGYDDDGYSTGGRDSAKRQKRKDFSSAQNSSSFTNNHNSVGVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L604</accession>
    <name>A0A9Q8L604_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755829.1">
        <property type="nucleotide sequence ID" value="XM_047901444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L604"/>
    <dbReference type="GeneID" id="71982174"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02296"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="37266" checksum="29C89BE575461D66" modified="2023-09-13" version="1">MQLQDRMVRADALKHITLSSSHSPATTQSTTRIIYNYHHDRNSPHARTTGSRVRNMSAAQQVFDTAELLEIIICQCPPYQIQELKSVARSWRDMINSSNAVRRSRVLLTLCSDAPDYDNDDVPLWDVNTFCTYYATDWVRLNPVFEKVHYEFGQMRIETTYYDITIVLPSSLSHSSSLEEFVTTPPVAAITLGTRCWSSDNGEWHVPDNENACTAYNKEGLKVKDILAVRDALIAAQHTSSDNQPPSVDTIVQAGFEIEGTNAQDNTLEDRMLHDLYFQGFLPRYRKASDMPGTRFEKAKQRDRALDWHPSMDSRKERLYYDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6K4</accession>
    <name>A0A9Q8L6K4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-lactamase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755504.1">
        <property type="nucleotide sequence ID" value="XM_047899254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6K4"/>
    <dbReference type="GeneID" id="71979984"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00106"/>
    <dbReference type="OMA" id="WEIFRTD"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF95">
        <property type="entry name" value="BETA-LACTAMASE-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040337189" evidence="2">
        <location>
            <begin position="19"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="93"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="4">
        <location>
            <begin position="416"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="579" mass="64330" checksum="245A64815B778EA9" modified="2023-09-13" version="1">MLASLIVFLLSHIAVGNAKCFEPTPAFPLPRWDNGGPELEPAFQLLETNIQDLASQAKYDNTSFSIEVTSLQGSLWSYHHSARVHNESRPGVTHVDSLSQYRIASITKVFTTLAILYQHDAGNLSLDDPVLNYISELRSDEYELPWKDITIRVLASQLSGIPREFAQGDLLNLVPDPSALGLPPVSQDALPTCDEYDSYKPCDRGEFLGELKGKKPLFAPNQKSTYSNLNFELLGLVLENVTGMPYSDYIQQAIFDPLEMTESSLSTPSDEHAVLPAMADGFNYWDVDEGVQAPTGGIYSTSSDLSKFIRYTLSHYNTLATGVNWFLPASWATGMNTFYGMPFETFRTDKILRDSRRPVTFVTKAGGLPGYYSRISMLEEYGLGITILVGGTNEILEPLNELVSVALVRAAEEIAWQRMAVDYPGTYAPIRSDLNTSLVLATSPSKGLHVETFISNGTDVLAALLSKSAPGDDAEQKQRWHAQLVPTLLFENEEAPKGEIWRMQVVSERSEEQQLSAGVWDEFCPTDLEGPLYAGVPVNKIVFWHELGTVELPAWNISMKRVSMSKDMKDNLFVQKQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L799</accession>
    <name>A0A9Q8L799_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756490.1">
        <property type="nucleotide sequence ID" value="XM_047900304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L799"/>
    <dbReference type="GeneID" id="71981034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01156"/>
    <dbReference type="OMA" id="PDGVYWA"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="102"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="629"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="665" mass="74566" checksum="D2B593810E1E300B" modified="2023-09-13" version="1">MGDSSMRDYGLAAPHGPNTTGHHVATADLGDMNNDEASVFRSLLLPDDSYDEDGTYWADMKLGKRINFIRKVDNEEAKKELKSIGRMIKADPLSPVSFYFRNMVIPGMGLLLEGYVLFSIGNVKPLFQSAFPDCWDNHTVCNKTWIQAVDYLEICGIIVGQILVGVIGDWLGRRWGLIQDAVIMFLGLVMLTASWGVTLNGWVICYVWSLFFYGVGVGGEYPMTATSGMENAVGSSKISTREDRLHRGRKVTSAFLMQGWGQWFNQVILILLLLIFHGGSSSAPYGKTLAQWTYRVSFAIPAVGTLWLVYYRTYKMRSASKQLQAAKKKSSVTGYDVKSLKMTFQFFGGRVLATAGAWYANDIFFYGNKLFQSEFISTISGDDASIMVNWLWNLLNIGVSLVGYYLASFLIDHKLYGRKWMQIVGFLGDFICFIIPAFNYSYYAEGAGVHKFMAMYFLSSFFNQFGPNSVTFLVAAEVFPTPVRASAHGFSAAWGKLGALTAAVLYNYIDIPMRFLVVPWFGLAGAILTWVFLPDTTGLDLKEQERRWAYIRAGRDEEYCGVAVHPQHLSLWERMWGLGKRYNAEKDYEQRVEEMRADWEAAMAARAEKEEAVADDDWSDEVSTFFERTRGKKGVSTFKPGDGDISGPSSGSIEEEKASEKINGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7B3</accession>
    <name>A0A9Q8L7B3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_00608</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756420.1">
        <property type="nucleotide sequence ID" value="XM_047899756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7B3"/>
    <dbReference type="GeneID" id="71980486"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00608"/>
    <dbReference type="OMA" id="NAINVRH"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13411" checksum="C1FF099557B83374" modified="2023-09-13" version="1">MAPKGKDKAKGKDAGEDKAKKGKKDGYQQINTRHILCAKHSKKEEALAKLNEGFKFDDVAREFSEDKARAGGALGWKLKDQLLSEFWEAAITLQPSTTAKPSWTECKTTEGYHIIMLEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7W7</accession>
    <name>A0A9Q8L7W7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxisomal trans-2-enoyl-CoA reductase</fullName>
            <ecNumber evidence="13">1.3.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_00212</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(2E)-decenoyl-CoA + NADPH + H(+) = decanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44960"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61406"/>
            <dbReference type="ChEBI" id="CHEBI:61430"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:44961"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2E)-dodecenoyl-CoA + NADPH + H(+) = dodecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57330"/>
            <dbReference type="ChEBI" id="CHEBI:57375"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:44965"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2E)-hexenoyl-CoA + NADPH + H(+) = hexanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44956"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:44957"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2E)-octenoyl-CoA + NADPH + H(+) = octanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62242"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:44953"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2E)-tetradecenoyl-CoA + NADPH + H(+) = tetradecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44968"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61405"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:44969"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33763"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:33764"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with PEX5, probably required to target it into peroxisomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.38" evidence="13"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756179.1">
        <property type="nucleotide sequence ID" value="XM_047899360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7W7"/>
    <dbReference type="GeneID" id="71980090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00212"/>
    <dbReference type="OMA" id="YAPAAMQ"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019166">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033306">
        <property type="term" value="P:phytol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052388">
        <property type="entry name" value="Peroxisomal_t2-enoyl-CoA_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317:SF7">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO11813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="29624" checksum="BACDC3C5B6E04B67" modified="2023-09-13" version="1">MTTATDNFLSPYRSDGKLYGFVCIVTGATHPIGRAIVTELAAHGAACVYACSSSPREDFNSLEAEVNKESPNTKVIGYPFHLANEEDTLMLIDDVLNSWGRLDIFVTSSSLLGPSSITDTTPSDLLKLFEANALMPFLALKYAPAAMAKTSPKGTYPNAQPKDRAYGSIIVVSSVASTLGSCWGPAFTMSSHAALGLVKSGVAALKGTGVRINCVSAGQIDVGVHFQDEHSKETNELERAGVPNEVARAVGFLASGFSSYVTGTNLVVDGGSSVSNPQVVPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L927</accession>
    <name>A0A9Q8L927_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900570.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981300"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01422"/>
    <dbReference type="OrthoDB" id="3942793at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="533"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="65512" checksum="F8F75ECC6297B98F" modified="2023-09-13" version="1" fragment="single">LKLAKNATLAWAGSSNTNTSNDVFKRDAATVLSQADFSFRYPTVPLDHSNFVSDIACSGGKLTGKLSEKAYTYAKKQWTGAGQVVFITSVDGCGRDAENDYFLAKTIAFSDKAKTFTAQGSDAGYKDVGVRFKLSWGDIGALPLKRALNKREVRSRSSTLDVSFEFSQYLDRYLGVACDAPWDHAVQLAKFGKEDKAWQKGELKKPTSKITGPGASKGKMTGGVDYGMGLYCVECGFGGGATIYGTMDVSILSFSVDTLEAGFNMHLIVGLNLGMEACVQYEKIYTKELARINLAGWKIPLLADIGPFISLSAQAGMKVKATGSLLVVSQKKVNLNFLDSSRSYSRGWTPRWDSELNILSGVWEADASIVDTPQMVAEGKFVTSAAISKDGKAVPDFNGGCYGIAWNIHFENTLQAVFQGEYIGSKVFDLIKPYESDPIAQGCIGYQDSGIDDGLPKVEPKDQGQGTGLGGNGLNSGGSGLSGGGSSGSKGAAKGATTTSAAPVPTGVLGSPRPKCTPGQVLDNPSKPGSAICSRYVTSSELAWSNRPKIYQDYDSPSAAACGADCLGVKGCVAYGYTSKGKCALLNKLTREIATVGSRGSPDWQFWDASCIKISTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Y3</accession>
    <name>A0A9Q8L9Y3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromatin structure-remodeling complex protein RSC8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757991.1">
        <property type="nucleotide sequence ID" value="XM_047902038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Y3"/>
    <dbReference type="GeneID" id="71982768"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02890"/>
    <dbReference type="OMA" id="QQFNEME"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02336">
        <property type="entry name" value="ZZ_RSC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041984">
        <property type="entry name" value="Rsc8/Ssr1/Ssr2_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SWIRM" evidence="8">
        <location>
            <begin position="123"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="382"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="385"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="504"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="595"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="684" mass="75471" checksum="861FBC3CF5BA4343" modified="2023-09-13" version="1">MESGFADEESRAPGQGSDELIQQENEAAEAKQESQDQDTSMVEDTEETAVKQQSTEGDAAPVSDNPLDAPEAPAPENADEAGEDEEMGDTKEGTPAVEPTTAVTKTAAEQSARSHLIDQNHAIILPSYSAWFDMHQIHNLERKALPEFFNNRNRSKTPAVYKDYRDFMVNTYRLNPAEYLTVTACRRNLAGDVCAIMRVHAFLEQWGLINYQIDPDTRPSNIGPPFTGHFRITADTPRGLQPHQPAAGSTITPGKPYAGTERLAIAGKADLNLEVRRNIYDDKGKDVTPAKAEGAESNGEATKSLEDSLKQDGKQYFCYSCGKDCTRVRYHNSKNPPASATTPKPSKEQRYDLCSLCFQEGRFPSSTTAADYVKLENERYQSIGDKESSWTDSELLLLLEGLEMFDDNWESVADHVGSRTREECVLKFLQLEIEDKYLEETPTANGSAGAASSDLAYLSGGRLSFSQFDNPVMSVMSFLAGIADPATTAKAAGKSVEEVRRTLKQRLDKEAEPGAEKDTEKEKEGSAQAEQVKPEGQDDRMDVDDTTSLATRSPPTSHDLPTTALSLTAARSAALASNTERQLSNQVSAAVNLQLQKMELKLQQFSEMEALLQAERREVERMRQRLFLDRLQFRKRVREAETKLAGMKISVPAGEKLSMTAEGATTGETAPFEDGMEGFMKHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA57</accession>
    <name>A0A9Q8LA57_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903026.1"/>
    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="24"/>
        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="491" mass="53067" checksum="122E63E90D6C9416" modified="2023-09-13" version="1">MATHDFANGRQGSLRLTATEPTPPRTPALAAFGRSTKGGIVVFSGGSAANSLVDVFHEIREANHSCSLSYVIPISDNGGSSSELIRVFGGPGIGDVRSRLIRLIPNDGDEAKATRDFFNYRLPKAYAPARLEWLDIVEGTHGLWTGISSPKKELIRSFLNSINTEAIKRIRPTSRFNYSGASIGNLFLTGARLFTGSFEAAIHLVSSICNVPGTVSVLPVLNTNFAHHIAAGLADNSVIVGQNNISHPSERAVDVSHIPTSPGQLLRAQTEEHDKVEDANMPGTLPTLRKPAIAFSKEDEEELPARIERLWYINPYGQEITIPANPRVLEAIRSSSCVIYSIGSLFTSIVPSLVLRGVGEAVASPSIGTKVLILNGTLDRETGPSNDAYTAMDFVAAIANACADSRGLSRPDACDYWQYVTHIVYLDSPTGPRIDKDAFNKIGIESLRCYGRKDENGKSGRYDSRALTQALEAIIGRKDPRGISRRNTLIG</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <location>
            <begin position="96"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13737.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAM0</accession>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71982801"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02923"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="221" mass="25291" checksum="6BD9ECEAC36BF077" modified="2023-09-13" version="1">MSEGDMYLDNEHAKVIKRGRKTTWSEVDLMDTKDAQTGYYGSTQILKYPQDSWPRKVNEEMRSKAQTLLTSMVEMIDIQVVVDSTPGNAGTACPNQGPLPADVFVTFPRGSRTLINMNRSLIEDLVMEKRPLYESLDLAEMMLHEFAHALQHATHGPRQEECFYKNARYSEAGYDFTSEIFGGVFQTVNVESLWCQHDPTGRQTHFDKYYDDDEILEDGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBA0</accession>
    <name>A0A9Q8LBA0_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040396999" evidence="1">
        <location>
            <begin position="23"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="15218" checksum="A380B35D0663320B" modified="2023-09-13" version="1">MSSFRLTTATLTALLLPALINASGLGLSDSGTAASCTGSQGCCIPSCLVDVSDFYGCNGNVAFSGTCQQNYDNPRNTQDVGGCSDVQVTFLKDPSGNPVIDLYYKPNKTYDRYSFSNCRQPTEGGSQCAPRGGGCDTKQILTGAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBG8</accession>
    <name>A0A9Q8LBG8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03085</name>
    </gene>
    <organism evidence="5 6">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047902233.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LBG8"/>
    <dbReference type="GeneID" id="71982963"/>
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    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000031">
        <property type="entry name" value="6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001280">
        <property type="entry name" value="Related to 6-phosphofructo-2-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF39">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="45"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="481"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="534" mass="60434" checksum="E5C7EE2C05CC7C09" modified="2023-09-13" version="1">MDTLLTADVAAKSTAFRRRSSTYVDAIHDLPEKESMAPAQLYSTESGRLFHSGRIVIATVGLPARGKTHISVALARYLRWLGVKTHIFHLGDYRRAFVGAKGEVPDDYFHVNASTSSVLLRNKILKKCREDIFHFLNHEKGQIAIYDAVNPLANGRRALAKEFEKHNVQTMFIESTCTDERIIEDNVRSVKISSPDYIGWKAEDAVQDYLKRINARIPHFESLEESDLHYVKMINAGERVVVNNCAFGYLSQRIVFYLLNLHIKSRQTYFCRAGTTRDEENYKGDASLSAEGQDYARKMTEALIAHRETERLSLIEQGAPESTALKPLTVWTSTRKRTVETATFLEQKGYRVRQRSQMSQINPGVCEKLSERRIRELFPEEVSKHEQDPYHHRYPRAESYHDLAVRLEPCILELEREQNDLLIIAHESVLRVLYGYLMACSAHDIPSLEFPRDEIIEIIPASYNNSAKRIHIPDLPSKLVPGSPEDIRIPVPPSGTISPLSGMGTPAEGGRTPESSGNEAGLLPLRRGNISPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCL8</accession>
    <name>A0A9Q8LCL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759280.1">
        <property type="nucleotide sequence ID" value="XM_047907527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCL8"/>
    <dbReference type="GeneID" id="71988257"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08379"/>
    <dbReference type="OrthoDB" id="3650889at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="14"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="921" mass="103535" checksum="5D61ADBA82C99365" modified="2023-09-13" version="1">MADTEPTAVVSRYRRYKAGTKKVVGWLARSASTCCDVAAKFSCFQSGSTSRSEIKVPSKVLTALADIIASAEADVAVPKHILQVLEDVIELRTECATWYGAQAVSDSTDLAARNKSHQHFIKVLKEVHAMLSKSTNIQASATTTSQSEENKSSKSKKNKKGPRKNSLDKLANLFEMLDLEEPILTPLGEAPSPSSKPPNEWNGKSLSLEDDQDNEAVALWYFLTDMNDVRQNVRQLWLEYLEGQTRLAVAGMVTETALGMIERASNDFVRQWPGFTDWMSMPEYLRITIGINNNLVYLFCKYSNALTKHAAANPSPADLICPTASFLLRTFAEGAWTFQQSLTTSDSGSLGGHVDGNRLSAERPYSEFEEVLLFMLPALTSLKTWKECYELTKRPTQLNLSIHDHSKITDGLMSLIDANQDIPVLDTPIWLVFACQICMDINEVVQGMGTCGADGLLKTTTDIQNSLNEALTWVQKEMNVSAFATRKSEFQLLESLVAGFKDNIKTIRRLESAKKISPLDTDDTWVLYKSRCTIPGLEVLPYRAALMIHAFKDWSYDLLTGVGNDDHAIVAMAHLYGAAKGRGLLQVPWEDMIFLERIQSGRKPLVTKTRNEASIMEYLRHYAIDLGADVAATIKPEFPANLDWKRMLKNGKQVSNRLSELRWAFRERHEENQVLGHQRGNTYDVVLATFTDRRKREDQARGSMKSSSGQIKYSPLQLLQTLTGYSKRDEPRVNFDYAGFSRLSTYGYAFQILQVTAEFEAKSVPLSATPLAYVTRTLRAMIEKCGKDFFTKAQQQCSGRIPKSHLPKFENTRPDPSDDIAKLINKYPGLSVGTSRTTVEFYDSQGSTTRFNDLLYNNDMRKIMPQGMSKATHIIVPVEELGEAEETARRDLPDHKLTDVYEYYDLIWDGKREQIHGRNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCP2</accession>
    <name>A0A9Q8LCP2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759150.1">
        <property type="nucleotide sequence ID" value="XM_047907743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCP2"/>
    <dbReference type="GeneID" id="71988473"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08595"/>
    <dbReference type="OMA" id="CEQHEAG"/>
    <dbReference type="OrthoDB" id="10670034at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="30625" checksum="DF9430AD2A1B580E" modified="2023-09-13" version="1">MARHQCQASQDDVLEVMLREGMVAQNIVMEEEGEDEPLTVEGEDYSSEITEPMASHQRQASQDDDLETMLRAEMASQNIVVEEEEEDLLIVESEDYSSEVTEPMHRTSPSPSPISSPSDGPISLNKFAQLMASSKAQARPSDNSITATPRVSLARAGPSKTRKAVSHRPKSRANKVYDQDEMEPLRKPKGFVDQTKARMLPLNTTLSVRAGVGSSAIFNSHPRRTKARVRKERLDTYSRPKELLWMTDEEYKEHVRKERKAPSKAAKEAMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDR7</accession>
    <name>A0A9Q8LDR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760047.1">
        <property type="nucleotide sequence ID" value="XM_047903952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDR7"/>
    <dbReference type="GeneID" id="71984682"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04804"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="29809" checksum="7761B47BB6F1BAA2" modified="2023-09-13" version="1">MPVHTYQQVAEDDDLSDIKQSIPTLSTPLDRTKPRGHNSRWLISILLCCNVLLMVLAMVLGVQLWRTQHDPPYCKVYPEAGSRRDQWKPLIQEVLFLPDPRYVNAKMFSSSEEAKHILSNWKVQLGHGGMVKIPTSDRHGLDPPLLADGIEDPYMEMYMLSGFRQLTCLHQILESYANLRNGVKDTKILSFDGVIAGCFDYVRQGTMCAGDVTLEGNTSARYPSLGEEQSWGTRHECRDWHSIREWEEEKKKWEVDFPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDS5</accession>
    <name>A0A9Q8LDS5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
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        <location>
            <begin position="123"/>
            <end position="167"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18135" checksum="0B99B835FB9EA61B" modified="2023-09-13" version="1">MTLKHTTANMPTPETEAHQTGKAAPKGFFSRMPSKQTQGIALIAVGGALILTSIYPYPVKSRTGNTFETTSTTNVQNRFIEAGAKDDHQGAVATSRTSQDDVSTAREGENRADAMARIHLKERQMSVGHEESHPNVWKKDDSGKGGIKDPTRPPTATQQSWGETKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGE7</accession>
    <name>A0A9Q8LGE7_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">5-Methylcytosine G/T mismatch-specific DNA glycosylase</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">CLAFUR5_04714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761289.1">
        <property type="nucleotide sequence ID" value="XM_047903862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGE7"/>
    <dbReference type="GeneID" id="71984592"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04714"/>
    <dbReference type="OrthoDB" id="5373744at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF5">
        <property type="entry name" value="5-METHYLCYTOSINE G_T MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <end position="776"/>
        </location>
    </feature>
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        <location>
            <begin position="829"/>
            <end position="926"/>
        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
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        <location>
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    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
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            <end position="918"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16923.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="101954" checksum="8558CD81EB45DC29" modified="2023-09-13" version="1">MSPMLNWPNDHDAALPQTQCATNMDEPRRRRKHDDRDRESKSSSLREHKHRSSKKSSSKQLSSESLDRESRRSATSHSQRAAGSRTSLRESVRESPRKSSGLPEMDRRPSGASGEVRSQTSYPSFSKAHSREAVGSREDVKASRHTPDTADLADDIPRRRNSSPAKAAPAPSRAPPSPPLTEDDPDIRRSGSGKSMRETAEDVKARMEHSRRSNDSPRSNGMQSAKSGASLRKEARFQESEISSMPGAFPEDEGKSTPNSSYRRTESTAASQPPSTLTEDTTDSDATSIAPDRKPSRAQRRPPNLATNDSPSSFDDSQPKTPVQDYAPFSAGARATPIIDVGIANKAVPHSMKTPMTARQVPLPPPPPPPPISGPKEAPRVDYLLKYGGLPTPVPKRLVQSPAPIQQYNVYQSPALASAAPLEEYAKVFSTVHKRLDDYLHVIHSNGSLAVATGYKSVARRLLDKLSQVFARDISSQRCDCVVCKTTPQPHMSDEEENGVSWGEILEFVAGRRELPQWPPFSIQPDESGLGISGATAAPMQKLDIDVPEEYRDHYIRQNQKTKRAVQSWLSQQPEVPSSPPEEADEDTLMFAMMTKLTVQQRNLFIALMHGQSFISEARAPTPAERPSAASNALRRAKKALQRLYRLERPPRDCEAAMYLLNNPHLHGMLATLAEVNEAEWDILISGRFDGFLWSGAEAPFPPSASQWGSQRAPSRGAMGGPQSRNTTPFSGFNAVPSRNPTPFSGISPDGIPMPSMFPSRGPTPGPNGMGVAPPAPVQLDEDTEIAVAAELERNLFLDMERLEDAFEILHGRAELVRQMLRERSAGLSAQAQLRRGSGFGDPVGVRLDTPASGVTDFEEEEDDGLGDTASLAPDDSASQISVNRRHRHRRERKTPNPETVPEENESVFEEHERTRKERSGRRSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGF0</accession>
    <name>A0A9Q8LGF0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904339.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LGF0"/>
    <dbReference type="GeneID" id="71985069"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05191"/>
    <dbReference type="OMA" id="WPPANGL"/>
    <dbReference type="OrthoDB" id="509124at2759"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25726" checksum="5B972424D9D12100" modified="2023-09-13" version="1">MASSDSTTWPPAAGLCSPTVPRQDAVFQSSGSCRINAPAALVFENVLRIQDYEKWNSFVPEARIVKQQFSRPDLSPDEQAAEASDFSHMKKDCIMHFSAVMNSAKPENKNQIELLVTDISTPDKPSDYLDAETLTDPAYTSDLSKLYRISWKSHGGFVTKGLRTERFHEIIVLGENECEVRTWEVYGAVLAYTVKWMYQKTLNEKFQLWADDLKKYSEQQAMASKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGP3</accession>
    <name>A0A9Q8LGP3_PASFU</name>
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        <submittedName>
            <fullName evidence="3">UBX domain-containing protein 5</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">CLAFUR5_04758</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LGP3"/>
    <dbReference type="GeneID" id="71984636"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04758"/>
    <dbReference type="OrthoDB" id="270602at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="459"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="59370" checksum="F9F2981A06CA0ACB" modified="2023-09-13" version="1">MDEQITTFVAFTGASTEQAQRYLQLADGNVEAAAGLFFENPDLGNASAAPAPSAPSASNREPPITIDSDDDLDLDADDVQETGSRPAQRGGPSVEDDEAMARRLQQEMYGGGGSGGAGGAGLDEDEVRAPMARTTETLVGPGSYDFRSDPGEMNAAIAQQMFNRQNRQNIARGGGQAGIFNQRSSAAIWNGDDPGDAEAHRQTLHRATNGASSASSKANHLAELFRPPFDLIAGFSFSDARDEGKENEKWIMVNVQDPSIFDCQVLNRDLWKDDRIRETIKEHFLFLQYNKDDPRGQEYVQYYFANMRDSDDAYPHIAIIDPRTGEQVKTWSGSPSPKPSDFLMDLHEFLDRYSLKMEKKNPVQKQRKESKKDVAAMSEEEMLEMAMQASMANGPSAAPKEDDPDALTKSVEFSGKGKAPAGTEDAMDVEPSAAVNPEKKDTPFSRISSTNAHEEPASDPVTTTRIQFRHPGGRIVRRFNVTDPVRRLYEWLKVSPFEGHEGEDFQLIAMGKNLIESLDATIADANLKQGTVMVEFIDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGS9</accession>
    <name>A0A9Q8LGS9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761499.1">
        <property type="nucleotide sequence ID" value="XM_047903480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGS9"/>
    <dbReference type="GeneID" id="71984210"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04332"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="239" mass="25816" checksum="5890768A540092FB" modified="2023-09-13" version="1">MSASSKASLEIVSTMYVTKGSDIVEVVVEETKTTVTKTATATANTEETTTTLSPSTADIFSEETTVEPSTTVTTVTEWLSEATTAKISQSSSRSQTSPSSVATSKMPEAMSTTTHIPSQHTHAPALDATHANSKSMLLTIGLAVPSFLAALGLAHWYWRKRRRAQVPAFEDARTRSKCRIDYNAEPLYPHRSIQRLSETSFSTTSPSGHDYMPVIEHDPPQLPPISLPGPGGAEHKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI53</accession>
    <name>A0A9Q8LI53_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">O-methyltransferase asqD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04862</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761414.1">
        <property type="nucleotide sequence ID" value="XM_047904010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI53"/>
    <dbReference type="GeneID" id="71984740"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04862"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF1">
        <property type="entry name" value="HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="6">
        <location>
            <begin position="52"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="224"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005739-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="45180" checksum="BD5C0EF37CF85959" modified="2023-09-13" version="1">MWALSWHPQPRMTAQRGTPFYGRYTHDLRQKIETPMHTIQRVTALNLWEAIAIRIAINMTLLRVVTEAAGPLSATQISQRCHAELHFTQRLLRTLNSFGVLERSISTDGTPTYSPTSICHTFAGQTGAASMRCWFDFFTPGFMLMPSQLKANGHKSFNSPDDNVYSRANGQPGRTTWDVLAESPYQQDWGTLVAEYTQNHKDWLDFYPVEDHLIHGAREDFDATSMVDVGGCTGSQALAFLQRFPSAPGRTIILDLPDVLPPPHARVDNLEYHPHDFFTPLPSHLDGARFYYLRYIGHDWPQGSWVKILQNVRVAMTPGYSKLIIHDLILPEEPSQTVAVQDLLLMGHGGGEDRDEARHRSAIEAADLRVCGIWDPRDGVSEVILECEVAEEAKDSNMNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIF1</accession>
    <name>A0A9Q8LIF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762430.1">
        <property type="nucleotide sequence ID" value="XM_047905374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIF1"/>
    <dbReference type="GeneID" id="71986104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06226"/>
    <dbReference type="OrthoDB" id="10584694at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="45238" checksum="9A82A6B4AF44A36E" modified="2023-09-13" version="1">MLESYETVDFKTIQQHTRTSLDCNMFRFPSPAHNNTDHQHHRSSPPQVTNSSRVNTETPTMKCESEEPSSSTADQNDFPLPNSFSCSQRKSHQRTKAMWDAAVSAINAYLQTDEDYVTSEEKKAFSSTIEQLRISAERLVSTLQQPLSPTHGHTDENLDQSREIEKPGHEESVSEERMVDLEWALEQERRKRKHLQEDFETFRSNMANVLTEHAQDIAELRSSLVPQKRKAVSSRTVSAAYTAVESTDLDTANPEPHRLKRLNIEGLNLDSFSWDLTLDRTQLIDPADGFVYLLPDYPDLKAMVLNTVKNLAPKPLSNRASSHKGLWQCLGTRVKGDGGVNRGTYVPPKEACVKCATARRFCIMFNIGTAPVNAETWLLPLPGVLRGDCGLGEEGYFRMVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ76</accession>
    <name>A0A9Q8LJ76_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NmrA-like family domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762753.1">
        <property type="nucleotide sequence ID" value="XM_047905494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ76"/>
    <dbReference type="GeneID" id="71986224"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06346"/>
    <dbReference type="OrthoDB" id="300709at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="5">
        <location>
            <begin position="30"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="374" mass="40961" checksum="F0B6C13E20CE3EF3" modified="2023-09-13" version="1">MADDNPEDNPPVEEEQQEEPTAEEEAEGPKRIVICGATGRLGGSVLRRLQSDGGWEIRAVTRTPDSDAATALADSGIEVVSGNYDDEESLITAFDQYFADGNDATAAGEKEQAQMYTIASAASKIDSLEHFILLSMPAGEKLAEDLHVPQFDFKDRAADQIIADCPDLIPKTNFLWSGVFTSNFWEGKGFDKPFEVPDTNGIHTMIHPSKPNTLVPFTNVSTNIGVFVSTLLAKPEIALPATYINCVKEVLTYEDALKIWSEVTGRTAVYVTVTDEDFQTLYGPGSLEFVQQMNFLAAAVGDWTSAYGALDPSSVIGAAELGIPDEELVDFRGSLEANKDSLLSWSPHREYRRWGQKSLRVLRSRQEVTVQLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJK1</accession>
    <name>A0A9Q8LJK1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762179.1">
        <property type="nucleotide sequence ID" value="XM_047904838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJK1"/>
    <dbReference type="GeneID" id="71985568"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05690"/>
    <dbReference type="OMA" id="ARMFATR"/>
    <dbReference type="OrthoDB" id="5366531at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="797" mass="89832" checksum="9A5A03B3DB83B1CA" modified="2023-09-13" version="1">MGATAFDRWLGTPSTLCFLRRLLAATGNANHYSLIPKRSGPIWHIRPYSDVASLESSRYEAPSATKARSRHSTANVPGNVAFEAEQSTVSHADIAERASRALWEHAEVAARRKQAQPGLDHHESRQNIRTWIDTIERRQRLDGFAGIHDVWKGMRYRGIDLPVIGPEADILWPMLLGACITAKFEKEQDNIRESILQHAKDLYTRSGALYPGLHRLVVGRAIQFKNKKLTLRWHEDFIKDFGASNIDLRLLAIDFARTLHSPDGKRNFSAIYKSSNQRNLYDPFMTALLLTGDDRFALRWHRIFMKHGDGPSAEMLATEAVQRMFRLDEDKSLPMLHRRPADLASPSIQGLQFPTLTRASMSTMVGEAHGIKPKEVSDTFVAKLFATSAFPLDMVLKGLGFFSIEELGPLALHELAIRSGSRDELVQRLHDLKLAGIEVGPSVYGQVLQKIAHDGPDELFDSFLASDQHPEAYDDLKLQGRLLAAFLAEGDLPRAHLALTALASGGESSNAAAWNVMLQHHVKAGQYRSIVLTLQQMQLAGVTVNNHTLVLMREHLLPPRALGRAPVHVEPSETENIRPLQVMTNVCMYAAQHETSVHHSIWVELLKRYGMMHRWDELENLVRWLVSWYSSRPNATRRARRLAEPSQLRLIFTGQMLQAIVTWGFNNAAERRLLGNKGTGARRLTVHGHCETWAQGVMLLKQLSSQGLYIAPGTVRNALLNRLWILFGPAWSLKASNEQYKEENELSLAHYVQHADEIWDRKLFDIRPELLQDTPGSTAKLMLAIFGPTRREAQVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJP5</accession>
    <name>A0A9Q8LJP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762810.1">
        <property type="nucleotide sequence ID" value="XM_047906336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJP5"/>
    <dbReference type="GeneID" id="71987066"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07188"/>
    <dbReference type="OrthoDB" id="3943630at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF4">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="35731" checksum="4CA6165D6662D1BD" modified="2023-09-13" version="1">MEAIAETDLDEIRRLQQAGATAPYIVPLGEHCSTPYLKTLATMRRAWIAYHEALKTPSFQAEDPFATMPTESGLQAFLLYIVMTRKGKTGGRLCTSTLKKYLINFSKLRHSRLGKTSDRAICKRITGYINHHLVKRGASQDSMPRPPATAPVIIDACDEHEFEHPRARLQLSLAILILMYFGVRPGEIVEASCHPGSNEGILYKGLSILVLNNVDGRRRLVVEVLLRNRKGVRSKRIKDLSMFLLEDFERPEMCPVAQVLALAIADHALDSIDTLDDLKARTTWIRIRESAKEVPVLRRLVGPRQAVSDNRILKAGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P398</accession>
    <name>A0A9Q8P398_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyamine oxidase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755902.1">
        <property type="nucleotide sequence ID" value="XM_047900406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P398"/>
    <dbReference type="GeneID" id="71981136"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01258"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF414">
        <property type="entry name" value="CONTAINING AMINE OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="525"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="538" mass="59443" checksum="C78270F40A3CCC52" modified="2023-09-13" version="1">MPANDAASQNVLRAARLKSGPISIGIVGAGFAGLRAADVLLQHGFHVTMFEARDRLGGRVAQSDRLGHPTDLGPNWIHGTSDNPIMKLASQTNTKLHASDEDEVAFSSDKIALDPAETAQYSQILWDEGLIAEAFAYSKSHGDLIDKEKSLYDFFAERTEKLFSNEYPAIAKRKRFTFLQFVNTWGCYIGSPVTRQSLRYFWLEECIEGENPFVAETYSKICDAVAAPVLEHADICLNTEVVNISSGQQQDQNYSNLKQAVVVTTADGNRSSFDEVVVTVPLGFLKHRKDIFEPEIPAALDLAFDSISYGTLDKVYITFPAAFWSTSNTSHAHDPPEDSVTDAEGPPVTASDDEVGAEADGWFHWLQPEYALSTNPERWSQEAMNLAVLRADCAHPTLLFYIQGPQSKHIANMIDLAEHEQDKDAKLRAYFEPYYSLLPNYNDANPACTPSAILATAWANDRFAGYGSYSNFQVGLEDADHHIEVMRHGMPDRHIWLAGEHTAPFVALGTTTGAYWSGEAVAKRIASAYGMEKNDSRS</sequence>
</entry>
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    </evidence>
    <sequence length="295" mass="32938" checksum="FBEDEC2E1D1D1CE7" modified="2023-09-13" version="1">MANEQNFRQVFPPSRGNRSLSCNVGSFRSRNSMTSISGPAKLDTIIDEDLMCKKALYYRNNSVRRSVSHHVQASGGVCMDEDLMYKSCTYQQRHRARTTTGNNMTSDKRSFEEYLAIERMYAEYRACAAGNPFYGDDDFVHTAASSHLKHHLPMGSNVRRVSRACAADESSLDAALSYSEHDLPGFCKVDQPCRSDSVDECLPRPVEAVQSYPQHDPPMSVEVKPLARSASVRDRLARPVKALQSYVGGLQRNNTHLGNCSRRVSSVTEASQLSFAWTGEKRLECGTLAVRRAKI</sequence>
</entry>
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    </evidence>
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</entry>
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</entry>
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            <authorList>
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                <person name="Samaras A."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </location>
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            <end position="3046"/>
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        <location>
            <begin position="2771"/>
            <end position="2868"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="644"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="703"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="817"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="888"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1064"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1464"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1518"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1753"/>
            <end position="1771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1798"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1812"/>
            <end position="1822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1958"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1977"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2020"/>
            <end position="2041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2055"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2140"/>
            <end position="2153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2372"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2399"/>
            <end position="2417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2427"/>
            <end position="2444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2446"/>
            <end position="2455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2470"/>
            <end position="2480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2487"/>
            <end position="2506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2596"/>
            <end position="2613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2636"/>
            <end position="2652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2661"/>
            <end position="2674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2788"/>
            <end position="2797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2804"/>
            <end position="2821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2834"/>
            <end position="2848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3046" mass="337532" checksum="95A816DC7841B382" modified="2023-09-13" version="1">MALLVAAIWLLSGAYWEGHVPWDTTRYEVEPTYTREIIIHDSIPVPYSYPVPLVRTETATVVRRETATVTVTASSGNESWSQGYVYAGSDDVLKDVWSGFGWGEKLFWFAECCLALIGAWTITQAVLQWIWPALHQGQQPPVAGGGDGGGQGGPGGGGGGGGGGSEAGNDDEVENLRSQNKILNDQVQDRDEQIVGLNTRIDGLVDENQEQADTIKHLKAKVEEQAEAIKRLDDEVDDMLKTGNIAAGPAAQRRLVNADGERVTQEDYDELQRNYDLVRQERDEILIRLRDLKTQDNEDSQGNDPDADHEKPNDKDNLQQKKRPSFFGGAQDAKDKPDPEAAATEQSKNVNDRDRLKQYNKELQNQVKALKQELKECQEHRGLQRGPRSGDKDLKDANEQSEADKRKLQHDYDALKNELEDTSRKLAECEAGKQSQNGPASGDGPSKGEFDKLKNGFDEREKEVKKLKGEAEVLSKELGEVKHKLDVCEQHKKQQAEPEKGGNPLKAEYDALQSQLHQLEEENEKLASDRDLLRIQLDDQTHKLERWKANTPLLWLASWSKEEERSTWLPELAAAEIRDLEEVIYRRAKRNHELEVTLRGVNRELAKCRKHEQEQSEVQGNDDQSKPKQKKSKIDNGDWAQQMQQEAQAKLDEQRRQMNHLENENRRLEHELEIARHGRQLRSDETANNAQAEDNRVIPLAIHRELQAECDRKHNEMRRLEREQEALVGENSLFEARIRNDLLNPVDVATVPLSQYEKLQMELRDAKEQVEEQAEARQVWDDALVDELFGSQNANDSDASIVLEDNYNAMPIISRAEQRRRSEARSRANNNVLRLRMPRVRDPAAQTQREQAPKDLDEARKELAKLSKAFEAQKKKLEECESHRKGRNSSQPNTPALPQSQSATPTPPVSRPSNARPRRLPKGVDGELLHDLRVALAEILNRPGFRELRGADFNTLRTLLYILPKTEKGGWETRLQSSSLLNWTNPSEAEVFESLATSDDRLRVILEWLSQNQELVIFPDPESKAKGKVDFVRRRPSPGSPDDSWQSSEDEDSRAGGDGSGSKPGDKKAKDQKPKEDEDKNDDNDSKARHRQGRGGSSSQRAGTADGAPPTSETGDQEFKEDSTLLDDSVKTENNQKSEEQTSSEDSTPAAGTQEAASDALIAAETAPFGGEPQQNDPLELLDLLDSELRPVLQAPLFRDGVFSINELVTALRSRFQLLPQAIPHFTASEVQQDLLRLMDNDASIPLERVDEHDLSLERPHGFHENGVPRNVDRLRVVPNAPLSDPASPSPAVARIYEVAQEAVEYIRSRHESPREQNFAEGDLFRSMDHPDIAHLINDRAKALYAAHSDQTSTSGPSVLFGDHHLPQAVRYLLMVDPAWWQGSTVQEAADTLRQWMNAADEVIAGDNAPAATPVAAIAAEEGPKQNDEQLSVDVKSPTAQSEDNETDAKSASPASTVFHMSKENTPQSQRSNANTYDARLDKRLVQPECTWFRRWDPFAGRMYYVQTSGRRQWFSPDKFEQDREGGDDHNDHDPQRKLEEPPRVRRWFVCPLRPTRDGAPVKTSFHETTGHTQWEKPADFRSDQWGRDDDISRPLGRHEKWHITNETWRERHPDITWQPLHSRCRWINGTFRDHWRQYPCPRCGDTDRSVAPHTVEKCPVPESQALTIHEQELMKLYQDQQITRDGLYYLFSIVGPGDQTSEGFFPWPQSTQEDEARRQAQYDIVFLRRDRANQGRALDEIRRWEDRMARGEEDDIDEADNEDDDNEDPFIEAKTEEPPSKGSLQLNTYGQGGHGLSSGPSSALSGTAPSFTPSGATSRVTTPLPPMVVPDLSQEWEAMYNSGERYASMTPAGRENYLRGVLSQWEKTHNYTPTQEQLDKSGGGQQDTTTTAQVVNSAQTSISGATGDSQQTVAASAPTLASPAMDITTQLLPAAQDLEDESSGELSTPSIAPLAARSTQPAVDETVTSGSATARPSEDIYDSRWATEPRPNATTNLPPNVPTGPKDPKSSGKHRGAVTGTSDSGSPLEKQSPSGLTTPQGRRASEDLKRVRSLKNTFTPRGNLGTSERPTDFSKPRTTAQEYGKASYKPAGPSSGAVNTPTTPGMMHPPAASYLPGPTTRPSENPNVQPHRPWENRDQASQPAQSQGSLQPASGHGGATGAANSLSSNLAATQEQEPQRNVQRFTAHMVPRKQLVNKLPSYEEIRAHIRRNPKGRNIIDIYLCYGNENLIPFFKKVREVAFEQGDNFILRDGSDLISTPPASPVRDGPSETPGEDSERSSSVIDVLDPITDEEICEAVHENDLIASLRERFSHRWSSESDFVLRILEMGTVSGDRLILNDDTGSKPAVLATASPIAAQNDAPASSESIPQTQTSAQITTSSTEPLVEEGNPNLPPANDQTSPTVPNVTLSTSVKPGTTAREVSTIVDQSEADNQATLGNDTTPSDDRNKDDLKTTSSTVASEDAKQDASAPSSSPEAELMLTASKAEDLQKDSASRKESLEASRPDNASPSLLARHIKGDLILLEDLEAPNFPTIDEVRAAIAENGDIGVLSERFENRWGNIKGRSSFWEMCRLVSKQISGSKFQLKEEPTALPASEAAPQPTPAASSQATNGAQTEPPSSDVVKPGMDSSIWAPAVETASSTSTAPAEEAPLKGSLQPVVTTPTSIGTDQASDGVVGGPQRAPQTKPPAGAPTDDEIIAVLRTNPLDTELRAHFSSRWADDNGEYQFWKRVHTMAEEEKVREDEGPKAGKKRAKRYQSIIRWKLREAAAGHQKTLPHATQSKQDPPPEDKKQQEKPVNPPTAATSSKRPSEGSSQSEPSIPPLETTKAKSTKGSSESTKSTASTTQPSSFPTTDELRAELAKRPSLAEFKAKFEKRWGNDAGHDEFWRQSKEDGYCVSPTIPLRKVKPIKATDQNQLRLPQDPLVVSSIRGLQMLRTTRRQEGGLMEVEVEATRVIAHVEDRKIEEDRRIQEDRIIEGDRTVEGDRGIGDEVRIITDEEAAMVAGSEVQDIKVEEASRGAGVEPEVSKGSRVHPSGGVASLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4E7</accession>
    <name>A0A9Q8P4E7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">3-ketoacyl-CoA thiolase, peroxisomal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01656</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757102.1">
        <property type="nucleotide sequence ID" value="XM_047900804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4E7"/>
    <dbReference type="GeneID" id="71981534"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01656"/>
    <dbReference type="OMA" id="QCGSGIN"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="32"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="287"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="411" mass="44170" checksum="6E41065256DA2FB4" modified="2023-09-13" version="1">MTTTDRLKSVLSQINPATSAVDQICQKNPDDVVITLAIRTPLCKYKKGGMKDTTLDDMVFKLLEQVRAKCGIDPAQVDDICLGNVNEGRAAHYCRAAALAAGFPNTTAASSSSRFCSSGLTATCHIANEIASGMIDVGIAIGAESLSEGNQRLPRAFADNIMKDREAEDCMLPMGITSENVASDFNITRDEQDRYAVESYKRAEAAQKAGLFNDELVPITVKKDGQDLLISQDEVRWGTTFENINKLKPSFTKDGKSTPGNSSQITDGAAALVLMRRSKALELGQPILGKYVATSIAGLAPRIMGIGPSIVIPKLLSRLGLDLHKDVDVVEINEAFASMAVYCRDKLEVDWSKMNPRGGAIALGHPFGMTGVRQIVTGLSECRRTKKKVLLTSMCLGTGMGMAGVFVNEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4P3</accession>
    <name>A0A9Q8P4P3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="12598" checksum="8DD731B5111D5908" modified="2023-09-13" version="1">MAHSYNNRDYSDITLKFADREIKAHKVILCTNSQYFKKLCGAGSQFEESRATEIELKDDDPDALDALLRFFYDQDLTRNDKADWRFQLELAKVSNKYLEDRLEQHAT</sequence>
</entry>
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            <fullName evidence="4">ADF-H domain-containing protein</fullName>
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                <person name="Stergiopoulos I."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="352"/>
        </location>
    </feature>
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            <begin position="365"/>
            <end position="722"/>
        </location>
    </feature>
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        <location>
            <begin position="764"/>
            <end position="890"/>
        </location>
    </feature>
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        <location>
            <begin position="917"/>
            <end position="1024"/>
        </location>
    </feature>
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        <location>
            <begin position="1061"/>
            <end position="1083"/>
        </location>
    </feature>
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        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
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            <begin position="176"/>
            <end position="186"/>
        </location>
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            <begin position="414"/>
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    </evidence>
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        </source>
    </evidence>
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    <sequence length="1192" mass="128692" checksum="274F4D7E13D906CC" modified="2023-09-13" version="1">MSLNGLDTPEVQDAYQSAIAEAGGWFLLKYTSRDSIELLGRGKSGVSEARNAILGYSEASPLYGLIIYRRRRILIKCIPDGTSRLLQARTAVHLQDILERYSPYETLLEITNGEGLNDTALAASFQLRTASASPSPSPSTKRLDEISEDAEDNGEGADGQARAETSSNSLSAPPRPKMDRRAEHMKKFGKRTSSLGVGKSPQLLGQQRAASPASPLKQSMSQYLVHEEAGHTSITPLETPLPEVSLPVESDDTEAVKQDSAQHSKEVQDISDSASQRTATDASDATEVPVSPKPSSKQPSSAAEMRDRDLPALPAEGSASSTQKSSRTGRSASMSERTVSTHSLADDPYGFSKFDELFKPKVKLAPRPVHSPEKIQSPAVARTSALPASFRPANRKQETLRPKSSGNGLAVPARPTPPAPTAYITPPPPPVPETPDYSARPTTRGSVRSAPSHKSHGMTPDKIRLMKAVELRRRQLRKSQEPPSRPTFDDDAPAIPKVPDVSDSIPTRTIKIIRTPEAASEQEAATDEEEQPQSSKADSGIEMHYRKQDKASGDRDLQSTPSASKPSTPEPGTIPTSQSTGTPVPPPIIQESPKEIDNASEETNSQLQPDDAASIESKTPTERSEFFVQEPASTEELPVPTIIMADGSRPMTSDEPILQPAVEADGEGSTVEDSGTEVPEESPSSPRRQNSDLAKRRRGYVEPLQTDLNSGNPDDFTSDDDDLLDELHSAIIVEATPVTVARSPLTPTLPGRRPSADTLASVRSVNITRMGSSPTDKGSDERLAPDLSRMVVPRTLTPPGEKRDSTSGLSRNVSSEISKRIQALSLQSRPLTPEVSPNGFAPRPTRSGPTSYRRHSSNRAAHSPARSGAPENAPVWSVQRDPATNRNSVSVTARIVRPNVISESVAEDSREALQQSEYVVNNERDAGRPGNRPASIRTAKTQSETSTPALSPVLSRSSTEARTMHSAGNSRFGRHKHQNSSIPVSTPGLDEFPPPPGTRTGGSTPSIRSNDENAAPKEGSKASRFMKRMSILPFGGSNKRKSGAQQQSSAASLFEYETIGAAAPTPGTTGTNSRVSSVHEKSDTPPAVVVGDLNVQFPDSLLWKRRIVTIDDSGYLQFAIAQAMEIHKGVALKKFALNDFKLPYVPDLDMQELSYSIMLEFHDGTTLQTACEDAMTQRQVLHILKTYWKAWA</sequence>
</entry>
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    <accession>A0A9Q8P5G7</accession>
    <name>A0A9Q8P5G7_PASFU</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
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        <location>
            <begin position="1"/>
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        <location>
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            <end position="712"/>
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            <end position="76"/>
        </location>
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        <location>
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            <end position="130"/>
        </location>
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        </location>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Q0</accession>
    <name>A0A9Q8P5Q0_PASFU</name>
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        <recommendedName>
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    <organism evidence="5 6">
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        <lineage>
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        </source>
    </evidence>
    <sequence length="1571" mass="170928" checksum="BDB2119BCA37BCF9" modified="2023-09-13" version="1">MRPPWSQPGTFDAGLLLSTVLLAKVRAAPALLLPDNHTNTTEELSALDVLLQAADPCYEYKSRPVDYTPPKCINSGENHWTMMFLAVNGTEDCEKARSAVETRLQDLHIGQHNVTCINSPCSPMVRLDLKVPSEALGPINDALHETFSQVPSGDDGVCVPLNCLVGTEWGQEKNMTCATEFAESVKVDLRQRSSSNPDKRASNITMPPLTAACKLGPSWYYMRINVDGLSDACNCLTESVEQDLTGISRKQFRCTQRSEDSLVKVWFNVSEESRITEFNHVLQQTLPDVMFGDRGLCIPKKCYTDEEAGLRNMTCAYEVFNQPVKVGNITERNLGGDVTRYHNKRNDSESTAPSPTDQSKSKTAHCELFKDFWDIYIFGGYDNTICDRIHDLSKEMLPKYLARKSLTCGSVGGEGNGQITLPTTEPERANTFNEVLQQAMPDVSFGETGLCVPRVCYQDFRRGIKNMTCAQNPPPPSNSSSPGESRPYGHNMTQFPKMPNTAVCTINDFAKFNPTYPTLDIDPRVDYDIGVGAPFSEDICNNLKQRINGEVSGYVVDCNKAEPIGVDKLNKIVEESFPDVDFSGNGTCWPSECYYANGTFHERIGGRKAAIKILNETCIAGQISTVSNTPQANLTESAATGTNGTLANTTETNTTEIIKQGGVIVPRTSDEEALAILPNRMEPNTAICYDRTEAQGYAVIVKKPWSAAECARVEQESSGIDFSCGPDGIWTAYLEGDTAIVYEFEEADEKYDQINERLQAAYPDVKFEGAGLCTSQDCYLPTFDEAIYVRNMACGVGLSDDSNASGTSSTGTDIANSTSPEPSVNSSLAPLPDEHIAPNTAVCFGQVRTGGFMVVVGRPLPEGDCLRLRHVFDIDDELDPTFHEFGCAEGAEWTSHFEGEAVTQVMFGSGLIYDFNGINEKLGTALPGVKFEGSNLCARPECYLPTSDEHLSVRNVSCAMTAPVEQAANTTLPEEAANTSLPGSEASGNSALAPLPPRVIAPNSALCLGDGTSDGYTIIVDKPHEPVDCEDIAERLANGILRPDGWEVACYDADNSYLYYFQEQPVLEISVGNLESWDYVELNKRLKEALPDVDFNGLGACDDRTCYLETSISVGRVRNTTCGGGTELFSNANSTSSSDIPVASRPSIIQASTTEANTTHLIKREDVPSPETLAPLPDKHIEPNTALCLHAGEFYDYSIIVGKPFEGALCERIEGALADGGLSLKDDTAWSIVCRSNRMMIPDYFKDEPVTAITVGEISSGEYRELNRKLREALSEVNFDRLGTCEHPRCYLPTSDEYIWVRNTSYGHGVDELPTIGNVSSVGELADLPDKHLEANRAICWNEGTESGQYRITVADPFEAEKCKKVQEVINSHFPKEVILAGSSSISCVEPGADDWFKDQREEVTVLYTTLNDSNVQALNNGLCEAYPDIDFPPFGLCAPYHCYDQTLEPRIKVENITCTADALEALRKRTHMPLLAIDLNGTLILESGRAASVTAQNSASFTISEPTLAVETVPAAGSINMTVPTPVTSSAAVTGITPIGTISLVSAFISTILSPSGGTGTMSTSSFSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7X6</accession>
    <name>A0A9Q8P7X6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS-type transporter calB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760718.1">
        <property type="nucleotide sequence ID" value="XM_047904047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7X6"/>
    <dbReference type="GeneID" id="71984777"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04899"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="20077" checksum="F6271671CC092FC5" modified="2023-09-13" version="1">MCRSTVRRLGYFVPFAVLAGVTTTIACGLISTWNPDTPPAIWIIYQMLYGLRGMGLQMGIIACQSAVTSAESPSVIAFLFFAENLVSAVFTIAGGAVFTQTLQRRVAILAPSVSPRAALASGGGAEAVRSLLPSGSPELPGLLLAFSDAVIAVYYLLMSLGVVSFGLAWAMGWVDIRKKTARENELRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P803</accession>
    <name>A0A9Q8P803_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_04569</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761015.1">
        <property type="nucleotide sequence ID" value="XM_047903717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P803"/>
    <dbReference type="GeneID" id="71984447"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04569"/>
    <dbReference type="OMA" id="TEWHPIS"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000544">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000236">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="70"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="416"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="502"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="600"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="727"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="468"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="515"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO16649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="875" mass="97217" checksum="FA04C7C57257BC6F" modified="2023-09-13" version="1">MTSTLDDEDLSLSIKNDGRRPSKDNVEPYQAPAQGTPVARTPQPQPQPHPQPHPQPQPNPKTLPARLGQYNVIKTLGEGSFGKVKLATHVVTGQKVALKIISRRKLVTRDMAGRIEREIQYLQLLRHPHIIKLYTVITTQQDIVMVLEYAGGELFDYIVQNGKMPEDKARKFFQQIVCAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVLLCGRLPFDDEYIPALFKKIAQGNYIVPQFLSPGAINLIRRMLQVNPVNRMTIQDIRNDPWFRHDLADYLKPPVEDFLDTGVNPNKAIDPHALAPGKPAAIQEKLHTDVTSKLSKTMGYAPDDVQEALSKDEPSAIKDAYLIVRENHLMRINPSMQEAQPEFGKSPPAFDGKTGSLPFRNSSIAMRGSPRAARPPTSPLGTGADHPRHGSTSSSILESRSPASTVAILPSSLPDYHAAYMKGQINKSSSPTNAQDDDGKPRTKEEQEATARRLKPHSRSSANLHRQPHEKPEPLTSMPDGGKHAKKQKPTKWQFGIRSRNSPSEAMLAIYRALQKMGAQWEVPRLKEPGDPGSGEASPERRDERERERSNSPEYSDSDPGSGTDPEYATHEEQERRRARRRNRSDIRGRERYGRYNDWGYAIPEDPWVINARFKKEGMFPAGVPHPASAHSSQVDLSTRRTSSVHMTSGVSSAAGSAENISATGPGTATSSKANSVYSGSTANDAFTAKAEENVWVYVTIQLYAIEKDFYLVDFKCAGYERLVKRFAREVMGSNESDVIQRDNAGDEYTSDDFEEDMNGDQLIGAGRTEGEKDITSPFPFLDVASRLIIQLAEAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P871</accession>
    <name>A0A9Q8P871_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P871"/>
    <dbReference type="GeneID" id="71984652"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04774"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350383" evidence="1">
        <location>
            <begin position="22"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="22348" checksum="F47071B9C113B0E9" modified="2023-09-13" version="1">MPSTLAKAVCLLQATLLTATATRNCVLGTHKFDDITPNPLLPQLQPSLGPYNGLSYNFRVAPQGLPINIIPGLKITLGPTTPASERNVIGAGAIHLDGLIGGQLGPQGIITATGKTKHFDLDSVYYACMINILPQVALPRPCTLTATEFGWDEGEGKYVRRSTEALAYTPDALQRAGMLFFEFRGLRKMREVTFGVADGRGGGGECGFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8L4</accession>
    <name>A0A9Q8P8L4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quercetin 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_06219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8L4"/>
    <dbReference type="GeneID" id="71986097"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06219"/>
    <dbReference type="OrthoDB" id="5370773at2759"/>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd02215">
        <property type="entry name" value="cupin_QDO_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053146">
        <property type="entry name" value="QDO-like"/>
    </dbReference>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040388725" evidence="1">
        <location>
            <begin position="18"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="350" mass="37924" checksum="C7AC578D9DDFD38A" modified="2023-09-13" version="1">MQSLTLLLAAFAPSVLSKVIEVTDALPDGAVPFVVRHLEGPKVLLADDVFRTLADTKNTISGSANAVAAGFSMLLTNGKPNDAVPPHYHVHWHETFLPMTGTVRVWANGKPRDLGAGDFAMVPGYANHSYQFVAEETEFLGMIQPAGFDEFFQKVSTQWNPEYNVPFPADQGIAFPAATFAQYAKAYDTVNMMQNEIGACDADWHASNSTLPANSTTPYFLANGAGPHYWYEQSGAVISPLATTVQTNGNFTISQVSMRKTAANATVRSWASKGHQFIYGMRGEVTFGVEGEDVKLIAGDSLFIPAYTNVTIKSSVNYNKFLWCSGGADDVDSQMIKQGVSWAYSTPPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9F5</accession>
    <name>A0A9Q8P9F5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS7m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762606.1">
        <property type="nucleotide sequence ID" value="XM_047904817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9F5"/>
    <dbReference type="GeneID" id="71985547"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05669"/>
    <dbReference type="OrthoDB" id="9972728at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14868">
        <property type="entry name" value="uS7_Mitochondria_Fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000006">
        <property type="entry name" value="37S ribosomal protein S7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047988">
        <property type="entry name" value="Ribosomal_uS7m_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="9">
        <location>
            <begin position="213"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="383" mass="41143" checksum="4F2365005786F849" modified="2023-09-13" version="1">MAAAISTIHAPAITMASALNSLPVLRACAFRPRATILRPQNAVIGVKRPAYRSFADDKSNQLPEAEEGDKGPNMDQAAHVSEEAAKMAKIQGGQGPDIEGQGTAVQDILKNEKDTRQNAPQVMQEEAKKGKDGPKPGTRPFSTLARRQVELTPASESSEPLDSSMLPTAAEQADHDAELDASSNLPVPQQGGEGHKFPLPELPLAQGLNKDYRYDPVVQQITNLIMQDGKKAAAQRNMATILNILRTTPAPTYSPTRPLLPGAPPASHLPLNPTLYLTLAVDSVAPLLRIRSQKGAAGGGVALQIPVPLGLRQRRRTAFEWILDAAVKRKSRGSGNDMFATKVADELIAIVEGKSTVWEKRLGVHKLATTARANLSYGIRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9U7</accession>
    <name>A0A9Q8P9U7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05423</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762742.1">
        <property type="nucleotide sequence ID" value="XM_047904571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9U7"/>
    <dbReference type="GeneID" id="71985301"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05423"/>
    <dbReference type="OMA" id="CLEVHGD"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="9">
        <location>
            <begin position="195"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="400"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="440"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="481"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="521"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="561"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="601"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="678"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="743"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="684"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="743"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="804" mass="89715" checksum="0ED7D5238B4C4355" modified="2023-09-13" version="1">MDGEDWDPATRRPSSNIMDYNYPQPEVEQTQHSTSPLARMASQSHNNRFHSSRHGKNPVRPRITTPSSSASHIPTMPIPIPTNPNVIPGNTLPSAPASPPTPAPSPTPQQRVPDWSTADPREEIGELDLNDDELLAQASATNSTRSYSSGYRHLRNEFANMDNPERERLLSELLNMCDGKTLGFVAQYVGPRLKRDPFTTLPNELCLRILTFIDDARTLARSSQVSKRWRELVSDDMAWKSLCERHAYRRMSDETPASPPRPILRPAEYHNPQHQHPYGYHGFLQQHSNSFVGLSSSAPDLTRRVSMSAVPSALPPTLAARGFSSKKGRRPKALSYRSHFKQRYQVETAWRHGGDVQTRQITPDQGVVTSLHLTPDYIIVALDNAKIHVFDTEGRHLRCLQGHVMGVWAMVPYQNTLVSGGCDRDVRVWDLTTGMAQHMLRGHTSTVRCLKMSGPNIAISGSRDTTLRVWDIRKGICKHVLVGHQASVRCLEVHGDLVVSGSYDTTARIWSISEGRCLRSLQGHFSQIYAVAFDGRRVATGSLDTSVRVWDARDGRCLAQLQGHTSLVGQLQLRNDTLVSGGSDGSVRVWSLQTYSAVHRLAAHDNSVTSLQFDDSRIVSGGSDGRVKVWDLHRGTLVRELGSPAEAVWRVVFEEEKAVVLASRNGKTVMEVWNFAPPPEIDDTSTLASTSTASSPGIQPYEDPTYGDRPLYDDLEEHPGFDTSSIQERERIRQEVHAANLEIERQQERERTKEMIQQQDEIMTDAYGRLGQQGGSQGQGHEHERDDEGGNDENVAPTTEELTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAZ5</accession>
    <name>A0A9Q8PAZ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763510.1">
        <property type="nucleotide sequence ID" value="XM_047906619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAZ5"/>
    <dbReference type="GeneID" id="71987349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07471"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040304719" evidence="1">
        <location>
            <begin position="20"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="463" mass="48556" checksum="CEF979DF4733F722" modified="2023-09-13" version="1">MAFSKFVVVAAALAGSTLAQSGTTEPQFDVAAIAAAGPPPEPSIAINVPSQTIHFDAVAVEQSAAAEQSAAAQDPSGTKVKRAACDPQILGKGPVPSPDTDQAFVSYSAFASAALAAPTPVGYTNTFKSLKAMNNALGYMGYTLLDSYYVPLCSKKCDEINGCSAFNVAFERSPFKDPSPKGGACDQPDTTTLIKCVFWAAQSTQPTPNGYVNQTVDYAEGYKAPTYLNSRAINAPNDCNGQSSYIGNQYWSDGKPFDSRRCAAACTAQTNANPGTPCRCFNTYVISKDGKSFGQYCAMYKQEWDASYATVDKVTYNGAPYSVSYSYAFSNSANNGLPCVKSQITACGSKVAGRCGTYQQCNPGQNCHCGSDVNGNTACFQDHSCGSQTCTTNAQCGSGSICLNSNSCCGFSICVQNTVCANGSNARHIFRKRQGADVKTAVHFPGDDSTVPADQTEAATPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBN4</accession>
    <name>A0A9Q8PBN4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="11">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_07667</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="11"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763837.1">
        <property type="nucleotide sequence ID" value="XM_047906815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBN4"/>
    <dbReference type="GeneID" id="71987545"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07667"/>
    <dbReference type="OMA" id="ARRCPIM"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="13">
        <location>
            <begin position="189"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO19471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="619" mass="67389" checksum="50221DA56A86FE2F" modified="2023-09-13" version="1">MEVLLRQSRAMCPFLNKTSPATLRSMSTSTTMQHPAPGGGAMSNLQIIARRCPVMGKALTVQSARGGNAALAGAFGGSRGYTAKVPRANLHTSRPNEAQAVDVRQVRREHFSPPNAKPANATTSAASQHLNTPPPPPKASQFNYEEFYQNELDKKHKDKSYRYFNNINRLAQEFPRAHMSERNERVDVWCSNDYLGMGRNPQLLKKMHETLDMYGSGAGGTRNISGHNQHAMGLEATCAKLHAKEAALVFSSCYVANDATLATLGSKFPNCVILSDSMNHASMIQGIRHSGAKKMVFKHNDVVDLENKLASLPADVPKIIAFESVYSMCGSIGPIEEICDLAEKYGAITFLDEVHAVGMYGPNGAGVAEHLDYENYANGRNPKGTVQDRIDIITGTLGKAYGCVGGYIAGSAKMVDTIRSLAPGFIFTTSLPPATMAGAQTAIEYQMNYQGDRRLQQLHTRAVKSVLAERDIPVIPNPSHIIPVLVGNAELAKKASDLLLEKHQIYVQAINYPTVPVGQERLRITPTPGHVKEFRDHLVVSLESVWDELGLKRTSEWAAEGGFIGVGEKDAPAVEPIWTDEQLGLTEVREQLKTEGAHGVLERVLDNERQQTIAVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBX0</accession>
    <name>A0A9Q8PBX0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764008.1">
        <property type="nucleotide sequence ID" value="XM_047909805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBX0"/>
    <dbReference type="GeneID" id="71990535"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10657"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="370" mass="41521" checksum="7056D95D604F0923" modified="2023-09-13" version="1">MPKPFTIPPGTLLPLDLDQDLPSDAEEDLKALFGERVLGDAGRKKRQDEARKAKDKSKRKTTGSGMFDTIFLDEHVPNPPPPPSPANDATQRATPPPPPSSPPPANDTTQPRPSDHRQNAPPPATDATQQAIRPPATDTTPQAAPAIAIGVPQESFAAYKDAWEKIGSNKCSPADLPLPLCTTNVQILRTQLRNEVKALHAATSRWEVLRREHLEMINTKTRDEKYTGYNIFKLRTEMFLADGVFADWKVEEEGGHAVVKLYWDAARTKDLDASDTEEDLRLHNGKLAALQEHFKKEKFRGHQDQLDRRTNCTHLDVERRTSQNMMVKAIYNGIMNLKEQTEKAIKRGGKNPQQEDIDAEKWVPDRDPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC23</accession>
    <name>A0A9Q8PC23_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10196</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764079.1">
        <property type="nucleotide sequence ID" value="XM_047909344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC23"/>
    <dbReference type="GeneID" id="71990074"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10196"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016594">
        <property type="term" value="F:glycine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000005">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000007">
        <property type="entry name" value="glycine dehydrogenase (Decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000007">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003346">
        <property type="entry name" value="PRK04366.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="9">
        <location>
            <begin position="89"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="9">
        <location>
            <begin position="570"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="879"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1069" mass="116644" checksum="341FB9CD8D7AF16D" modified="2023-09-13" version="1">MSASAAALRLRAQWLATRRPLSTRCLVLNKPPHRPAVAQARLAALQTRTTHGTVRSFYSSSTESTTSADPKHDDSNNASIFAPLDTFPRRHIGPTAESAEEMLQALDPPAKSLDDFVQSVLPPSILSKKNLSVEGPVPESGSVPTSEGGYSESQLLARLREIASENKVYKNYIGCGYAGTRVPEVIKRNILENPAWYTSYTPYQPEISQGRLESLLNFQTMVTDLTGLAIANASLLDEPTAAAEAMTLAVNSLPIARQKRAKKVWLVSHLCHPQTIAVLESRAQGFNVTIEVADILADNSKKLDEIGQDLIGVQVQYPDTLGGVEDYRGLADKVHKLQGTFAVGTDLLALTLLTPPGEFGADVAFGNAQRFGVPFGFGGPHAAFFAVSDKYKRKIPGRLIGLSKDRLGDNAARLALQTREQHIRREKATSNVCTAQALLANMSAMYAIYHGPAGLKRIAEKVAKMTQVLANGLVEAGLEVRPGVAFDTVIIKKHDAPGFASKTVQNFLTNFRVIDNDHIGITIDETVGKKQIEEIFRAFTTDPVDVDALAQGVEATGGVPDFFKRTSTYLEHPVFNSYHSETEILRYMHHLQSKDLSLVHSMIPLGSCTMKLNATTEMVPISWPEFANIHPFAPADQAQGYRKMIQELEDDLAEITGFHSVSLQPNSGAQGEFAGLRVIKKYLEQQSGGKKRDICLIPVSAHGTNPASAAMVGMRVVTIKCDPKTGNLDIQDLEAKCKKYKDELGAIMVTYPSTFGVFEPEVKKVCDLVHQYGGQVYMDGANMNAQIGLTSPGTIGADVCHLNLHKTFCIPHGGGGPGVGPIGVAEHLAPYLPGHPLVADVGGEKAIAPISAAPWGSASILPISWAYIKMMGARGLTHATKITLLNANYIQSRLKPHYDILYTNENGRCAHEFILDTRKFVDTAGIQVIDIAKRLQDYGFHSPTMSWPVANTLMIEPTESESKNELDRFCDALISIREEIAEIEQGKQPRHGNVLTNAPHTMKDLITSEWDRPYSRAKAAYPLEWLEEKKFWPSVTRLDDAYGDMNLFCSCAPVETVEGMTGVDAPMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCF6</accession>
    <name>A0A9Q8PCF6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764284.1">
        <property type="nucleotide sequence ID" value="XM_047909583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCF6"/>
    <dbReference type="GeneID" id="71990313"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10435"/>
    <dbReference type="OrthoDB" id="3647541at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="51835" checksum="1B902603952E728C" modified="2023-09-13" version="1">MQNMLSRDWFGRAWVLQEAVLARHAVIRCGRFEEDWKVFCAFVCDYRRYYRDDARGLVKGTWQYNGLDGNRDRMNLAMSKELEMLRWINLPFSIATISAARTDGLEIPILQLLGYVRLQSATDARDKVYAIMGLLSEDQRSRLPRPDYDAEVMEVYIALAASVVLSSRSLDVLAWKNPYVEPFFTGMPSWVPDWRSLQEAGNVGNERVQMPVISPRHGAEPFGTYDPVHNASLYPISPYNFDFTNERVLHARGVHVDAVADWSEQIGGLDSLPPPRYKEDFTFHQEQILDSPLRDMRTKLVDSNTLTSDAFWRIVSHDQYIKRLNRYRSETRRLGKEGYTTLGGVKFPPVTPEDEEAILKLEYRSGIELKGARDLILRTRTGYWGAFPRNTRPGDTVVVLFGARKPVLLRKHRSFHVFVGECYVHGIMGGEVMLGKQIQNYEAETEVFHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCL8</accession>
    <name>A0A9Q8PCL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764379.1">
        <property type="nucleotide sequence ID" value="XM_047909740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCL8"/>
    <dbReference type="GeneID" id="71990470"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10592"/>
    <dbReference type="OMA" id="WMPWGWG"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF177">
        <property type="entry name" value="PROTEIN YOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="340" mass="38387" checksum="D1DE2E9D94EF36ED" modified="2023-09-13" version="1">MFGFIADILTSVTSILLPVFFSYKALRTSDPAVLTPWLMYWTTLSLFLAVESQLYFILSWVPFYSWIRFGVHLYLVLPGQQGSVFIYKQHIHPFLEDHERQIDRMISDAHAKGKAAGLDAVKRAIEYVRVNVLGQEPRRPTPPPSRNVSYTTHLFNRFAMPTARESLATAGTSHIFNMLGKVLQQSTYPDATSHDAAARDLASSGTLIPSDLRGEDRNDFVNTQRERLRTLLQAFDAEAYDADDAATSGSQSRSGAPQAPSSRKSYLSPDAPYMHASRSESEFEDLGYETMPDPDQFRPRQDRDRTPPGRTPGEQKPGWSNWIWGNYGEKDSVVEPKKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD51</accession>
    <name>A0A9Q8PD51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Importin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09872</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764649.1">
        <property type="nucleotide sequence ID" value="XM_047909020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD51"/>
    <dbReference type="GeneID" id="71989750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09872"/>
    <dbReference type="OMA" id="WVAKTSW"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000244">
        <property type="entry name" value="Nonsense-mediated mRNA decay protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="896"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="911"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1048" mass="119417" checksum="AD239319462197B0" modified="2023-09-13" version="1">MDAAALRSRIQATLDANAEIRKQAEGELKAAEDSSGFLNGLLSVLEQEQDASVRLSTAVYFKNRVNKGWSKVEDSQTTSPIISEEEKTVVRRRLVPIIASAAPNIRPQLIVALQKILHCDFPKQWPDFVSITHQLLHSQEIPSIFAGLQCLLAICRTYRFKLGDSRQDFDKIVEMTFPQLLNIGNQLVDETSLEAGEMLRTVLKAYKHAIYFELPMQLRSHQSMVDWCTLFLKIVAKAPPENSMMEDHDERELNHWWKCKKWSYVNLNRLFVRYGNPASLQKGNGEDYTAVAKSFIANFAPEILKGYLAQIELWVQKSVWLSKPCLSYTLGFMDECVKPKAMWDHLKPHMPVLIEHLLFPVLCQTDEDLEQFEEEPAEYLHRKLNFYEEVSAPDVAATNFLVTLTKARRKQTFEVLTFINNIVNRYEAAADDQKNPREKEGALRMIGTLANVILGKKSPIADQVEYFFVRHVFPEFRSPHGFLRARACDTLEKFESLDFKDPSNLTIIYRNILESMADPALPVRVEAALALQPLIRHDPIRQMMQQNIPQIMQQLLKLANEVDVDALANVMEDFVEVFAAELTPFAVALSEQLRDTYVRIVRELIERHSSKEGDDGYGDFLDDKSITALGVLQTIGTLILTLESTPDVLAHLETILMPVITITLEHKLYDLYNEVFEIIDSCTFAAKIISPTMWQAFELIHRTFKSGAELYLEDMLPALENFVNYGWKTLLENRAYLDAIVDMVRTIFKDEKVGGVDRICGCKLAEILMLNLKDGIDNYVPEFISLAMTVLTNDELKVKSYRIHLMEMVINSIYYNPRLALGVLEANNWTNKFFSLWFSSIDGFTRVHDKKLSIGAITALLTLRTEEVPQSVQQGWPRLLQGIVRLFQTLPAAMKNREEAQREEDFGLGGDYDDDEEEEDEWEGEDWEAEENEETTDIKDESTAYLDFLSQQASKFNAAVGEAEDDDELEEESLLETPLDSMEPYNLFKDTLATMSAQQPQFYQQLTNMLGPEEQQVIKAAVEQADKIKQQQAAAAIQGAADPQANGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD67</accession>
    <name>A0A9Q8PD67_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_10051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD67"/>
    <dbReference type="GeneID" id="71989929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10051"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="83" mass="9447" checksum="F73E1692D832D8FB" modified="2023-09-13" version="1">MSYVSNVHFDRKERAWFEYHYSHSSSVVYSYGLKSLDGKDASEGKQIVAAVLEEEEQRRLITGIGLAKIADIGYVELYSVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDA1</accession>
    <name>A0A9Q8PDA1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_09932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDA1"/>
    <dbReference type="GeneID" id="71989810"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09932"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="124" mass="14283" checksum="7BB7CB70CF5F589A" modified="2023-09-13" version="1">MSISESRAKQVNKWSSINNYIRKLISTAHVISDGTKTYFLNLTKDLMALTLRPDSSGNLANEWRRVLLTVHDPIMRSFLGLDDPDGNGGDERFKRIENLSDYLRYSAIFSEDQVERTDVEEEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDF3</accession>
    <name>A0A9Q8PDF3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764767.1">
        <property type="nucleotide sequence ID" value="XM_047909568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDF3"/>
    <dbReference type="GeneID" id="71990298"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10420"/>
    <dbReference type="OMA" id="VMQPPCS"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="281" mass="32363" checksum="359B89184E70B611" modified="2023-09-13" version="1">MAITRGVTKAAGTAAAIGAVFGTTELLEMILLYLQVNELLCAQQICTRWRDTIRASTKIQQTLYLSPFGDKLVHAIDDGPGPKNFDLDDWNFAHWIVRSDKGSDVVVRPILNPIMHRYFFTWYNNFVSILKTGFIDPIFDRSAYHESCKWKSRNPLPEPCEDDIGPRTERQLLALHREGASWRRMYVMQPPCSHITIMCDDQRSTFTITNEKGVTLQDLRDGVYQHWSSCRDCPTAYVIERWDFEGFRLQNLQLLKEIPTSIDLLNSLRRPNIVRLPGVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK8</accession>
    <name>A0A9Q8PDK8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764889.1">
        <property type="nucleotide sequence ID" value="XM_047910329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDK8"/>
    <dbReference type="GeneID" id="71991059"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11181"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="824"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="848" mass="92087" checksum="2CEB6FAB744DE0EE" modified="2023-09-13" version="1">MSMPLNEPPYLPPRRPKSATDFKAKRLSQAATPLYLPPRPVSLVAPTRGPLTPVSELTQVPYSHRSQRDSSASLPASRHVSSGDQAGAGTSQYATSDLSQHSLKEDIIEAVPQPSRPRPVARHSLLRFESKLSPTKSSRKGLDFRTSLDRAATEPQTESTSRRPRSYPCSRSGSMYRGIDSNSPTDVTPIPSIPPHMQNHDPCRLPPLQQPMELADLSRSSSQHSTARRPKVVRPRASWQSMLSLDNLLTYREEKADWKRASSFMQSPVESDYERHPTLTSAPDTIPLDDMSNHKRVDTPPASGAATPDSASRPASVIIPDSPPPTSRFRHVIAELGFCFTIAMTQFLAEYMISGFAIELPKLIARHSSDDDGGMGKFWPASLLSLILSATLLIFARISDMYGGYFPFMFGVMWLGVWSLVAGFAGLGTLLDVARAMQGLAIATFTPATFAMLGSIYHEGPRKNSVIGLYAGCAPLGFFGGFLVAGALPDGAQGWYFWIAAILAFTTAVTAYLTVPHDRTDRKQLGLKMDWSGAFLITAGLILLAYALAVEPYANASDPSRSGWSFPMVIAPLVVSVACLGTAFWVEGWIAKCPLLPFDFFKPKDVKSFSLMSLCFYATYGVWLYESAQFFQNAHATGTENGIDGVTLAAWYTPTAVGGLILCVLSGRLCHMAPIMASLLVSAMAWIAAPLLLALCPLPLDYWAYVMPSMVCATLGIDITFTISCVFMAATQPLRYQGLAGAMSSILVNLAMSFSLSISEIVSEKGRSSITLPSFQSPEYAALAEEQEMWGFRSAFFYGAASAGVGLIICALFVRISRSVVNPQPVDEEQARPRPSSEASTLVDGSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF28</accession>
    <name>A0A9Q8PF28_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765626.1">
        <property type="nucleotide sequence ID" value="XM_047910025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF28"/>
    <dbReference type="GeneID" id="71990755"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10877"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000022">
        <property type="entry name" value="28S ribosomal protein S5, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="177"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="118"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO21260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="38417" checksum="3E6FA709488706B5" modified="2023-09-13" version="1">MSSAQTYRCLSCRLKPTVTQTANNARRSFHSSPANEARKRATRRGAFPKTKSLASHLRPYTAREQQILARRYTPEQMNAIKLGEKAVSAKDMKLQGRFRTDPTRIDYIDDFASARPALDNATPNDAPLKVGANETERSHRMERKGKPPRRQDTEELDPHMLRLSQQTGLDKDQIRKIRVKNLITHRVVNQTRMGKIQSLYFLTIAGNQNGMVGVGEGKAAEDEDGRRQAMMNAIRNMKPIPRYEDRTIYGEVEAKVGASIVRLSSRPPGFGNRCQHLIFELARAAGITDLAARTPRSRNKMNVVKAAFQALTNQRLPDDIARARGRKLVDVRGVYYGGLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFE7</accession>
    <name>A0A9Q8PFE7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09397</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765805.1">
        <property type="nucleotide sequence ID" value="XM_047908545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFE7"/>
    <dbReference type="GeneID" id="71989275"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09397"/>
    <dbReference type="OMA" id="KFGRFER"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="84"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="38871" checksum="005632A43B978652" modified="2023-09-13" version="1">MNGTSSDVNGKAPLGSDSGSSHPVAPLVKVQPPRREDLQPSYAKAIEPDTEDAAQHGWYGSMINALGSCVGTLGAIPCCIICPNPYKPVAQGNVGLVTKFGRFARAVDPGLVKINPLSENLIQVDVKIQIVEVPKQVCMTKDNVNLTLTSVIYYHIISPHKAAFGISNIRTALVERTQTTLRHVIGARVLQDVIERREEIAQSIREIIDETATGWGVAVESMLVKDIIFSQELQDSLSMAAQSKRTGEAKVISARAEVESAKLMRQAADILSSAPAMQIRYLEAMQSMAKTANSKVIFLPAQNQTVQQQLAQAEAVGEGPSSYRDYGTANHMTGNENQSEFAGNTHGFQSAVNARVVENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY4</accession>
    <name>A0A9Q8PFY4_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766131.1">
        <property type="nucleotide sequence ID" value="XM_047908257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFY4"/>
    <dbReference type="GeneID" id="71988987"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09109"/>
    <dbReference type="OMA" id="YSYVAPY"/>
    <dbReference type="OrthoDB" id="376826at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17316">
        <property type="entry name" value="Perilipin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="28630" checksum="62D6F18EAF939919" modified="2023-09-13" version="1">MPHATSEQPLTNGDKLSSQFVHHLASYPVVNDSIKAVQQNPYGKKSIELADGAYQRFGKPVQPYLETPYSYAKPYVQKADEIADSGLSHVEHRFPIVKEETHTIVDNVKSLVWWPYSYATDTWQDEYSKTAKSKNRGDGLPLPTLVLAYISFNLRVASDFLHTVANTVGPKYEESKKKGADYVREAQNQAEHYKKVGQEKVDEYTKFGQQKAEEAKKQGEETVDEAKKQGEETKEQAKSKANGAKEEAKKKADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG58</accession>
    <name>A0A9Q8PG58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766192.1">
        <property type="nucleotide sequence ID" value="XM_047908017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG58"/>
    <dbReference type="GeneID" id="71988747"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08869"/>
    <dbReference type="OrthoDB" id="3650781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="26602" checksum="109ECF31CA02BAA5" modified="2023-09-13" version="1">MASNTALDAKKAGRRVEAFAAVQFRNAFPNLEQSVLESITREAVTKACDQIVQQHEAMEASKARQNLLDLPAEVRNRIYEYVLAPGGREMRTVELRPRSTWRGVSQVMGRASFASEPSQNQPLFSTASQKTPALCRVSTPVRLETLPMYYANTSFILHLVIDIPFHEQPKVCSSIEHWLAAIGKTSVQLVRSVQVIIARNSNASQSYNHEEIMQGLGSRLQGLHDRYVDIRIAKGPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG92</accession>
    <name>A0A9Q8PG92_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766415.1">
        <property type="nucleotide sequence ID" value="XM_047908569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG92"/>
    <dbReference type="GeneID" id="71989299"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09421"/>
    <dbReference type="OrthoDB" id="5371646at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14399" checksum="719183A7BCBE329B" modified="2023-09-13" version="1">MSTNTHQWALLLQIVARMDRPIPWAEIDVPEGRTQKGCVVMLDKEKKKIREAMAAEGKELAPFKAKSTPKKRTKAADGEEGDEKGTGSPKKKKPTPRKKKATKDDEKVDEAEKTAVKEEAAAEDGDEELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHK6</accession>
    <name>A0A9Q8PHK6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-xylulose reductase</fullName>
            <ecNumber evidence="9">1.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Xylitol dehydrogenase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_11880</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767037.1">
        <property type="nucleotide sequence ID" value="XM_047911028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHK6"/>
    <dbReference type="GeneID" id="71991758"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11880"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046526">
        <property type="term" value="F:D-xylulose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="14"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO22671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="37944" checksum="4F9C281DDDC21D8E" modified="2023-09-13" version="1">MGQQNPSFVLEKAGHVKYEDRPIPTLTSPYDVLINVKYTGICASDVHYWVHGEIGHFVVKSPMVLGHESSGVVSKVGDGVRSLKVGDRVAMEPGIPCRRCVRCKDGKYNLCPDMAFAATPPFDGTLAKYYALPEDFCYKLPESVSLEEGALLEPLSVGVHITRQAGVRPGHKVVVFGAGPVGLLCLAVAKAFGASKLVSVDINEERLQFAKKYAATHTVVSQRESAQDSAARIIKETDLGEGADIVIDASGAEPAIQTSIHLLRIGGTYVQGGMGKADITFPIGAMCSKELNVKGSFRYAGGDYALALELITTGRVDVKQLISGKVKFTDAEKAFSDVRAAKGIKTLIEGVEDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHW3</accession>
    <name>A0A9Q8PHW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_11915</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767136.1">
        <property type="nucleotide sequence ID" value="XM_047911063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHW3"/>
    <dbReference type="GeneID" id="71991793"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11915"/>
    <dbReference type="OMA" id="SIYHRFM"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000003">
        <property type="entry name" value="Tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="442"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="468"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO22770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="58010" checksum="AE51FC4626486D2A" modified="2023-09-13" version="1">MAEEGVGAPPEVKNAIDVRTTLPQSEQQIDPYNVSGGVDEQGNAKAIDYDRLIQQFGVQKLTEEHLERFEQVTGKKPHRLMRRKLFFSHRDFDKLLDVYEKHGTFMLYTGRGPSSGSMHLGHTVPFLFTKQIQEMFDVPLVIMLTDDEKYLYTRQKNDGRQEKGKAVEDFLDFAHQNIKDIIALGFDPKKTFIYTDYEYVGGHFYWNVSEFESLVTLSQATGAFGHKGETNIGMVAYAAKQCVAAFPSSYPELFGYANYSHINPDPKGLRRHKALADIPCLIPCAIDQEPYFRMVRDRCPRMTHPHPKTTLILSKFLTALQGPGGKMSASDANSAIFMSDTANQIKKKINSHAFSGGRETLEEHRQYGGNPDIDVAYTYLSYFLEDDAELEDLATRYRSGDLLTGDMKKRCIEELQKFVTSFQEKRSQVTDEVMREFMKPRKLEFKGNPNPTHPMSEVKSEANGPAEKVVREDGKLTKGQRKEQKLAEKKREKEEQKLAERPKAESAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJP2</accession>
    <name>A0A9Q8PJP2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768043.1">
        <property type="nucleotide sequence ID" value="XM_047912397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJP2"/>
    <dbReference type="GeneID" id="71993127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13249"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040507021" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="131"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="415" mass="45620" checksum="8682B5A7D8765628" modified="2023-09-13" version="1">MGISAHLWFSLAPLRLRLTIYPAHRISAGPTSSTQKPQSDLNTRVQQTTILPATMQRIARFFSRKKPDHQSTEVLFDHDQTLHAQENSTPPVKPSSDLSQETLYNEVRRPSLADSEDSTCQSTITLLSSTHYFLKKLGNGIDAAVYAIIPRDFADSFVAGLTDATPKDVALDVLRKAVIAVKVANGPLTGPGNAKAAMETEIRALKALGNGRMLDCDEGGGTWCTMLMITGGTLQQFYGWLCRQVTHKPMLMPKCLVYHLLTSLAEALLALHAEGITHGDLHPGNIMLRPKPSSDCYPDVVIVDFGHAAISPKSKRLVRWREVDDFESMSTCLAIVFDVEEVGFLHSFARRIREMDGGETPQSVLGEVVECAGASRQRWQRLENPVPSAMGEDLAGTTITDGELERTILGLEGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK20</accession>
    <name>A0A9Q8PK20_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768327.1">
        <property type="nucleotide sequence ID" value="XM_047911903.1"/>
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    </dbReference>
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        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF19">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="51349" checksum="FEAECC361DC42162" modified="2023-09-13" version="1">MNLPSHLAPERLTIMIVGDSMTHGEEGDWTWRYRIWEWFQHAAPHVKVRFVGPYTGTVPPPKSHPPLPPRLPGEKDPDERDSMAGGYAKDISPDFDREHFAHTGRQMKQAKDEIYSQVSIYKPDMLLTMLGFNDLAWFVSSGAEETLEDTKTFIDQARAANPDIRFVMGNIPQRTHTGRDDLVKKTSKYNSLLHHAISGWSTSRSRIEGVEIERSYGYVPDECKGTFDGLHPNALGDYQIACAFSRTLHHAFGYGNKPLAMPKHIPKRALPVPSNLKAFGAPYGVACTFDAVYGCHGYDTRQRKQGESDWNEGYTGMNRIDHTFTSPGEKWEFQVRASGGLHEKGEWSEVVRATAERNTAPPPKNVQVYSTPLGFEATWEPLDDSWEVDRYVALYQDRTENGFLCGVASKGTSASVNDLKQGHRVDVMMQTWTAAGPGAPEHGGTIVVGSGVFSRPASRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLV6</accession>
    <name>A0A9Q8PLV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c oxidase assembly factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769138.1">
        <property type="nucleotide sequence ID" value="XM_047912650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLV6"/>
    <dbReference type="GeneID" id="71993380"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13502"/>
    <dbReference type="OrthoDB" id="2100652at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042432">
        <property type="entry name" value="Coa1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28523:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21791" checksum="E4D02FF95633C2C1" modified="2023-09-13" version="1">MLPRPRLRPTGLLQSLNPSRQIGARRTLVAAPKAGSGPLMERRADRALPTVSTGDNRWLKTMPIFLFIVVGSTLAIFNYQKQSSSVVSSTLYALRTNEEARRILGDEIYFASKIPWISGELNQLHGRIDISFWVKGKRAKGLMRFKSERKTRMGMFETLEWSLQMEGEEGRVSLLEGSGRDPALNQKGETVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR80</accession>
    <name>A0A9Q8UR80_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_06651</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17 18">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the TOP6A family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763890.1">
        <property type="nucleotide sequence ID" value="XM_047905799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR80"/>
    <dbReference type="GeneID" id="71986529"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06651"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1360.10:FF:000018">
        <property type="entry name" value="Type II DNA topoisomerase VI subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013048">
        <property type="entry name" value="Meiotic_Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01551">
        <property type="entry name" value="SPO11HOMOLOG"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="13">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="14">
        <location>
            <begin position="97"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO19524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="30611" checksum="AB39861E69E70BF2" modified="2023-09-13" version="1">MLSCQRGNAHPDIYYRDPALFGNQTYVDRYVDDIAFTFGLSRASLNVSAVAKGLVAGAITFHRTDGSSTTASNDRDGLLVPSLKDMLAVDLQAVKWILVIEKEATFRSITAGLFWDTIATQGIVLTGKGYPDLSTRALLHFLSTASPQNGFASPPVYGLADFDPDGPSILSTYKQGSKSLAHESEDHCAPHLQWLGLRSEHLYLNQDDTHASQGLLKLTARDRKKAIRMLEQDDDLAVPEDWKAELRTMLMLNTKAELQLLDAMTGGMVDLLTAKLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR93</accession>
    <name>A0A9Q8UR93_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Baeyer-Villiger monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763833.1">
        <property type="nucleotide sequence ID" value="XM_047905906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR93"/>
    <dbReference type="GeneID" id="71986636"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06758"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="542" mass="61686" checksum="D20D35F7626C205D" modified="2023-09-13" version="1">MSTAEQEVDVIVVGAGFGGCYLLHKLRESGFSVKVLEAGSTLGGVWCWNRYPGARVDCEFPYYGFSDPAIWRTFPWTERFPSDKELRAYFHHVADVWDLHRNIQLDTRVVEARYQEHQNRWHLKTKTADTVWKCRWLIAATGTSFKQHIPEWQGRELFAGALHHSALWPEDMTLEAKNVAVIGAGSTGVQIVQEASNVSPRVTQFIRSPNLALPMRQRAITEEERLAYLPQMPHVFRACRSTPSGLPVERPGLKVFDESAEKRNARLEHGWKLGGFNWSQGSYSDYIVDPKANRELYEFWKEKIRARISDPAKRDILAPEEPPYYMSTKRPSLEQDYYESCDRPNVEITDSPIVSFTKTGIVTEDGKERQFDLVAVCTGYDAVTGGLRTMGIKGRNGIDLDEKWKDGVVTNLGMLVNGFPNMFMVYGPQAPTSLSNGPIFLEMQGDYILRILLRQKEEDIESIEADKEAEQAWRTHCLDLAERTLLVKTNSWYMGTNIPGKKREYLVYLGGLPLYQQKMEEALENWQGYALSSSSDATASNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US21</accession>
    <name>A0A9Q8US21_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764673.1">
        <property type="nucleotide sequence ID" value="XM_047908967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US21"/>
    <dbReference type="GeneID" id="71989697"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09819"/>
    <dbReference type="OMA" id="DWRNLTN"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040543781" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="544" mass="61179" checksum="202EF2D5A4D9EFB4" modified="2023-09-13" version="1">MQLLSCVLAVSGFVSLSFAFRQPGKGLFDRTERRQENAQAKRAQHLQPRQESPPDPSFVNRFLNDKTQPFWVNGSAIPKVPFDMGESYAGLLPVSDDPDETRKLFFWFWPSLNQSCPQEIAIWFNGGPGCSSMIGFINENGPWMWQDGTPYPTLNMYDWRNLTNVMWVEQPVGVGFTQGEPNVTTEEESSKQFVGFYHQFAETFGVKGFDIFLTGESYAGYYIPYIANEFITQNNSDYPLTAIHINDPIIGGNTAQQGVTVYPYIEYWSNLLNLNDTIMANLSATHEDCGYKDLLDKYFTYPALQEPFPTPRDPFDGNCDILDYFDYAVNEVNPCFSFYRISDRCPLLSSTQGHILLSLPSPDTAYFNRTDVQETLHVNVGTAWEVCSSDPVFPDMKNRSSPYDTDLSLPPANNGVLRNVIETTNRVIIGSGNLDALLNTNGTLFAIQNMTWNGWQGLEDFPDRDFISPYHPDTYQSSSGSGVVGKWGRERGLTFYQIQLAGHTVPGDALGPSFRVMEVLLGRVDNLGVHEPFTTDVEAGRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US48</accession>
    <name>A0A9Q8US48_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Septation protein imp2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10178</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764850.1">
        <property type="nucleotide sequence ID" value="XM_047909326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US48"/>
    <dbReference type="GeneID" id="71990056"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10178"/>
    <dbReference type="OMA" id="ETTVRWN"/>
    <dbReference type="OrthoDB" id="27823at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106006">
        <property type="term" value="F:cytoskeletal protein-membrane anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07651">
        <property type="entry name" value="F-BAR_PombeCdc15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000045">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000164">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
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            <end position="267"/>
        </location>
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        </location>
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        </location>
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            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20484.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <dbReference type="PubMed" id="35471194"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="47346" checksum="06C39399F5FFBD0B" modified="2023-09-13" version="1">MSVAATTGDMSIFSLPTELIQRIARDYSSTPAEAALVLTCHRMFHIIGGKSFQVLGRRSFSQETRYLPELYLLRPNIPEAMRRDYKRRDEKREFLQLLLRDLPKGYAIYCHQHIILHICQPKPSKVEGAKLWKETCACKARYRLPLGATGGPPVGAVQLVARGAAGLEQLAHYESLEKFTVAHHICCIADHPRDFSTEPTMPIYKDVTCYGRKVGNNVVLAMQYRAHISKKRLAFHKGCADETKNHAYLLLRWSRFGGNGFDLYLAVQDLIDLVALGHAAKDIPMGYMVTRRLGGLAGIPYTRVRIATTRGGAVNVQLDMFADLRQGLARPRVPHLPLGIIVLDDNIVTRRRHRATGTAGPYIDTQALLQQRWLRETVQEHFQDHEEKLEEVRKSKLRWKISSIRFEGVRAGLFRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US81</accession>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="23419" checksum="DEDB3DD1DD861229" modified="2023-09-13" version="1">MSSSMYHQWWHAIARAMAPPPKPDDHCSQSAQSKPPSPSPDKQYLLNLPPELRNRIYEYALFHSTCISFPNWLITEPGLLRCNRQIREETYSMFWSLNTFHFGDTKTAEIGLTGLHAKKIVALRSVRACSADVAVQSRDWLKYVDFRLRGLWAACEEKGLAPDVIKMPLKVTGEEEVQWVSLEEADDFEIGVGGFVVRKKDLMPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="3 4">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71990731"/>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
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            <begin position="144"/>
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        </location>
    </feature>
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        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19422" checksum="D015F4507E19DBDF" modified="2023-09-13" version="1">MVLFTKGIVTILLLTNSLTSATIQIDKNNFYFDDLQKVFDVDFTSDKPDSCKQWQHHLEVAYVEALHMLTAAIEAVAEIHEAPPDEDDPEAAETLSSWRKRAHVWRAMLGEYPGCESPEQPNVAQHLGETAERFQSLLEAHQLNRRKDQDITNDVATTSCNSSRPATQTHET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT07</accession>
    <name>A0A9Q8UT07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-phenylalanine transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765661.1">
        <property type="nucleotide sequence ID" value="XM_047910399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT07"/>
    <dbReference type="GeneID" id="71991129"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11251"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="35469" checksum="5238A689E1BF491F" modified="2023-09-13" version="1">MELMRLTNSGTEATMMALAVSKVCTRRSKILVFAGAYHGGALSFAGSGGKGSEVNVGAPHEYLIATYNDLGSVRALLRRPEDRSDVAAIIVEPMMGSGGAIPASEEFLRGLREVANEVGAVLIFDEIMTSRMHRGGGIQSQLPMAMRPDLTTLGKYLGGGMSFGAFGGKKSIMDLFDPRRPDALAHAGTFNNNVLTMAAGRAGLEQVFTPERAAQLHEKGDVLRKRLQDVGQGTLLKVTGYGSIMCFHFISTPTEDIKSHKDLADADSTPADLLHLFLLKRGYYIARRGFVALSLALSDADFDGFVQAVADFVWEYRHLLDNGHRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT92</accession>
    <name>A0A9Q8UT92_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765992.1">
        <property type="nucleotide sequence ID" value="XM_047908422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT92"/>
    <dbReference type="GeneID" id="71989152"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09274"/>
    <dbReference type="OMA" id="FNTNDGY"/>
    <dbReference type="OrthoDB" id="3556830at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17651" checksum="A04F10EEBB63E011" modified="2023-09-13" version="1">MAPALETVAHLATRALESRQTRCYNTIYGRRCSYNRWGGWGRWVLLGVIVGLAVLIFFAFACMTARRRRKVGRKPFMGTGWAVPANMKHNGAPMQQHYQSPPLQYGQQNNAQYGQNADYYGGNQYGNNTQYQKPAGAPPGQSYGQYAPPSEPPPAHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTH2</accession>
    <name>A0A9Q8UTH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766156.1">
        <property type="nucleotide sequence ID" value="XM_047908619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTH2"/>
    <dbReference type="GeneID" id="71989349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09471"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="75"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="151" mass="17445" checksum="2013E20663B07098" modified="2023-09-13" version="1">MPINITIHTNWLTRRNIRHAQNEIEYGTTSAQRDAGRRALEKIAMEEIMESVKKAIGDSDNEIKSAPPAPARKALQVRIYVEPDFGGGRLGLWIKKEDTVQHLKNIILEEMEVPIERQRLLYLGSEFQDGQRMDRYHVDHDAVIELRVRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTQ2</accession>
    <name>A0A9Q8UTQ2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766424.1">
        <property type="nucleotide sequence ID" value="XM_047908733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTQ2"/>
    <dbReference type="GeneID" id="71989463"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09585"/>
    <dbReference type="OrthoDB" id="4937900at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF14">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="472" mass="53414" checksum="F698F03BB3173032" modified="2023-09-13" version="1">MPENRERKSHIKSRLGCSQCKARRVKCDEIRPQCGNCRRRQESCSYKNPNPLSTASPDASGSEQINDHQASAQLHLKQLALMHHYATSTYKTIAMRTQDPAVYQLELPRLACQHSYLLDAMFSLTSCHLAYERPAEAAEYVADAVRYQARALETYRHKLETLSPEDCQGVFHASALFGVLALAFRSVDPESTRAIRPTETMTQLARLWRGTALVLRASQQLLPPETYNTSFQMPIWDMRSGSNDTSCQAQIYLDMLRSRARAGDLVRPSIPEETSEDPINHCEVYLEAIDLLQELFQANRLEHSRIVAWTIMVPAQYMELLTQGQPIALAIALVYSVVMEEMENFWWARPFRHQLVDQLVPVVSICDPQLAEMANWVVGWTKRLNELVPPAQEYDTVPLNDIGVDVPSLRLCRQEQGAVTQLEHLGLDKSMATLRAVKAGVLLQLDAAVEHMDCYSPPNSEERECSLSDLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTW4</accession>
    <name>A0A9Q8UTW4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766604.1">
        <property type="nucleotide sequence ID" value="XM_047908123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTW4"/>
    <dbReference type="GeneID" id="71988853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08975"/>
    <dbReference type="OMA" id="QTRCVQI"/>
    <dbReference type="OrthoDB" id="5295771at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="40977" checksum="DF96E1664DCAA77F" modified="2023-09-13" version="1">MRRQALEHVCLSCRHARQAQSILSRTSRRYVQISATPSSHEPLQTLEPAASASSSPSADARFEVVGNPFSLLSASISASQKLYTRKGTLVGFNGKAENTVSSLSLLEPFRRAALGIPFLYQRITSTTPYTALIATKSPITSLVVVHLDGRLDWMVARRNALLAWTGHTLSLKPRWNMKMSMAHWGSTTVTGRGLLALSGKGLIHQISLKTGEAYVVSPRNVIAYSMMQRAPQPYRFKSNNLRLQIPNPFTWLPDTRCWRTIRDSTFYKLLRDASFTVRTWARRTIWGDGLFLHFQGPATILVQSRATRLSDSFTNQDVNEVADAPAGAVPAALHAKSAAEAGAAVTTTVRADQPTTMSYAAVSNTGSVKFDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTX2</accession>
    <name>A0A9Q8UTX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,3-dihydroxybenzoate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766697.1">
        <property type="nucleotide sequence ID" value="XM_047908588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTX2"/>
    <dbReference type="GeneID" id="71989318"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09440"/>
    <dbReference type="OMA" id="QDIWDAK"/>
    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000043">
        <property type="entry name" value="Amidohydrolase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF31">
        <property type="entry name" value="AMIDOHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G05840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="74"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="38872" checksum="26E6EC69B582A906" modified="2023-09-13" version="1">MLGKVALEEAFALPRNAEITEWWAGLFAIDPAKHTKEINDINKLRIQKMDEHGVGYKILSYTAPGVQDVWEKPKADALAVEVNDHLANSIKGHEDRLGGFATLSMHDPQTASAELRRCVKDYGFKGALVNDTQRNDESGSSMIFYDGPGWDSFWETVQDLDVPFYLHPRNPTGVFYDKLWAPRKWLLGPPLSFAQGVSLHLLGMVTNGVFDRFPKLKVIIGHLGEHIPFDLWRINHWFEDIKKPLGLDCKKTIRDYFQQNIWITTSGHFSTPTLKYCIEEIGVERILFSIDFPFESFEDACNWYDGIDNALDSKQDVLDIGRENAKKLLKLDAFKDDKAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUC5</accession>
    <name>A0A9Q8UUC5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767013.1">
        <property type="nucleotide sequence ID" value="XM_047911479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUC5"/>
    <dbReference type="GeneID" id="71992209"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12331"/>
    <dbReference type="OrthoDB" id="3639531at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="471" mass="52937" checksum="08F8F2BFC43B25DB" modified="2023-09-13" version="1">MLSIDIHRMTDHPDNTTITSQPGQRDKVAAASDTNKRSRLLSLPQELQDIIFDFAYPAQDGTKYYDRRDWTDREQEARRRDSSRVIRPFPSPKVEEFMLSRQYFAGASRAWAANQDFEFDTGMSGAFRIPYIDNREYEAGIVRKHATTVTVGMYLPSFGARCRQHFACLRVLSIYLSPRDFESTEPKFVWTQTLDEADFAVVAGALNLDKLRGLRTLRLVPDTCYYTKSPQEEQQWVDNVRDFEAYLKPFITRPLEGHSRTKPSTETHRTAMREPPQTRPRPATESTGASSKQSRSLAPAQTTLSIPTLFTGGPPKLPKTMQRSRTAKSALQKPRKPAARHVDRGNKSQQKPDVNGAGKLDSRGTKRFNGVREQKSRKKICIRQRRESEVVAALLFDVDIELRKVLKDDAKAVSLIPQQPGGTALGMLAVGSALPEIIASGLGAVRSEPPQSTMMAKQDPVMGGWCLCFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUF0</accession>
    <name>A0A9Q8UUF0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitin deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="4"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767222.1">
        <property type="nucleotide sequence ID" value="XM_047911127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUF0"/>
    <dbReference type="GeneID" id="71991857"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11979"/>
    <dbReference type="OMA" id="PNNYFRP"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10958">
        <property type="entry name" value="CE4_NodB_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF137">
        <property type="entry name" value="4-DEOXY-4-FORMAMIDO-L-ARABINOSE-PHOSPHOUNDECAPRENOL DEFORMYLASE ARND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="3" id="KW-0170">Cobalt</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="71"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="263" mass="29880" checksum="8A463836BA57267C" modified="2023-09-13" version="1">MPLFSPFFRLPGRWRSRSARKRRMAVQTTVLIVILLLVLPLYIIYKPPNVVIGYFQNRFPHVLFQINTTRKIIALTVDDAPSPYTREILDILKANDASATFFVIGGQVPQHEGLLEDIVNAGHELANHAMHDEPSISLTSSELKEQIDHVDRYIDSAYTAAGKERAAHYFRPGSGFFSERILEVATTAGYRTILGSIYPHDPFISAWWLNAWHILSMYRPGAVIICHDRRSWTVPMLSKVVPALKKKGYEVLSVSKFLEMAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUI6</accession>
    <name>A0A9Q8UUI6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11811</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767342.1">
        <property type="nucleotide sequence ID" value="XM_047910959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUI6"/>
    <dbReference type="GeneID" id="71991689"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11811"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO22976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="156" mass="17603" checksum="3DB67C5E4466CEC6" modified="2023-09-13" version="1">MSDEGHHTSKTRSRLNTISAHLQSQPTMSQQRPFITCHVLDTVAGKPGAGIDVKLKLISPANATTSHWTARTNNDGRVPAWTSLTDINEVVEKVKAELKDDDQMVWSLTYDTEAYFGKGKTFWPEVELRFAAKKEEEHYHVPLLLGPWSYTTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV51</accession>
    <name>A0A9Q8UV51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767911.1">
        <property type="nucleotide sequence ID" value="XM_047911705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV51"/>
    <dbReference type="GeneID" id="71992435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12557"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="19268" checksum="C49AEDDB0A984914" modified="2023-09-13" version="1">MAQPRREKADYKSRDTGPTQYDSERKSLLDLPPEPWSKIGHLVISNRKIHNTSAVILKHRIASKHHGSSAYATTGLPSRASAELLREELLPLWFKTKVHIVIRLSSSASEISLIGQWLRAVSAESRKLIYPAAASTWGTRGPTELRNLLGVETRFVQVPDSGAGVGQYRIEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV68</accession>
    <name>A0A9Q8UV68_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO23679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV68"/>
    <dbReference type="GeneID" id="71993119"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13241"/>
    <dbReference type="OrthoDB" id="3647238at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="50"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="110" mass="12402" checksum="3741D5CEA2C11627" modified="2023-09-13" version="1">MDNAVPQASSAYPAPPLESGQFRLLHLEAGTWADEIRCTLQSSVLRRGGFEAASYAWGPLHLGRNITLQGVPKWPVTDNAFDMLRRLRYTNKSRVLWMDALCINQNDLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV95</accession>
    <name>A0A9Q8UV95_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768046.1">
        <property type="nucleotide sequence ID" value="XM_047912390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV95"/>
    <dbReference type="GeneID" id="71993120"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13242"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="86" mass="10385" checksum="9067DBBA76EA64BD" modified="2023-09-13" version="1">MTRKKTKTKRKMKSRAAERKKKKKKKKKKKKKKKKKKKKKKKKKKKKKNRQYRMQDWPSSHRLWACSSGDLSSGRALQTVSHCSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVV2</accession>
    <name>A0A9Q8UVV2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate-forming reductase cicB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768719.1">
        <property type="nucleotide sequence ID" value="XM_047913110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVV2"/>
    <dbReference type="GeneID" id="71993840"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13962"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="564"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1020" mass="112023" checksum="EE13360A64A01DBF" modified="2023-09-13" version="1">MGDMAAATSSDDFHRPVVTLRDPDCPFHSILDLVDFNAKHNPNHTFAIQLTKDVDGGLTEKLVISFRTLKSTILACSNDLAQTVLGGAPEASQPVALLMASHVCLIIYMFALMHRKVPVVLLSARLSPSAIEHLLKATGTSKIIASANLLERVKDAVANHVSFEQFSVHEQESLEALIARDESMSMSSHTSLAQGTPTKHTEHSLILHSSGTTGMPKPIYHTERYLLAFATCHDLPVTPDGPCLSTLPLFHGYGLLPSCLALSVGLTVCLPPKSEIPNAPAMVHYLRLVNAGSLISVPSVLEDMAASDGLKVLKQLAFVAFGGGKLKESAGQALIVGGVPLLNHYGATESGPLAPIFVPGSDYDWHYFRLREDAGIQLQPTGVNDDGRQQFRLSVQPPGWNSIFQIQDELVRAPLSVHQNYAAVGRMDDVLVLANGEKVRPGILEAQVTEHPDVKSAIVFGNDQTEVGLLLQPAHRVDVQEHGRFVDLIWPDIQNANLLMDAHAQVLSKQCVIVVPHDAELPRSDKGSILRREVYTTFEVEISNVYTRLDNSVNKKLAEPLRWENFEDDISTMLHKHCHLRSQPGGLSPDDDLFARGLDSLQAVQLRRRQQASLANSQKMALQAESLPRDFVYRFPSIRKMADAMRGVHHEEFDTEFDQVAMDKLVAQYSTSNRVHIALITGATGGLGSHVVEHLAKSPNIHTVFCLIRPEPECDPKARLLKALSLRGLDLDEVAESKVRVLECDLASQDLGLSGEDYQQVLTSVRWVMHAGWPMDFKLTLASFAPAFQALRNLLSLVDKIGRSGRDATPKFVFISCCALDIGYARAKLVCEAIVEHASTHCSTATVQYIRMGQLCGNSKTGIWNEEEHIPALLKSSLVMGALPEMSGTLSWIPVDQAAEVACDILLDTGSERLCFHVESPIRQSWADMLSIIRRQLGLHKTTAYDQWLAELSQTASTDSPAVKLLPNFQTHFERMACGQVTLDTFAAREVSPALRRVGGVSDVEIGRYVARWRESGFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW31</accession>
    <name>A0A9Q8UW31_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768962.1">
        <property type="nucleotide sequence ID" value="XM_047912825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW31"/>
    <dbReference type="GeneID" id="71993555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13677"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26204" checksum="EC2E233E0284E679" modified="2023-09-13" version="1">MVQHLAAATAITAAATTDEPSAAEEVFNITELFEFIFERVEFHDLIRSRRVSQTFLLHIKKSAPLQRRLSWLQIEPPSRTLYTFLNFQLCFPHYKSHGPFSMGHSGPTYSRSGQDELLYLHFHNRDPTSPESGRLQITPDPDASWRSHRIADNDVRICITYDDDVSTYGHELLKAGSTLGDVYDWLCKKQELTWQAIEEELSGGWALISLNPRSREARALTDGGQRLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWP8</accession>
    <name>A0A9Q8UWP8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769488.1">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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                <person name="Lazar N."/>
                <person name="Mesarich C.H."/>
                <person name="Petit-Houdenot Y."/>
                <person name="Talbi N."/>
                <person name="Li de la Sierra-Gallay I."/>
                <person name="Zelie E."/>
                <person name="Blondeau K."/>
                <person name="Gracy J."/>
                <person name="Ollivier B."/>
                <person name="Blaise F."/>
                <person name="Rouxel T."/>
                <person name="Balesdent M.H."/>
                <person name="Idnurm A."/>
                <person name="van Tilbeurgh H."/>
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            <dbReference type="DOI" id="10.1371/journal.ppat.1010664"/>
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        <scope>X-RAY CRYSTALLOGRAPHY (1.62 ANGSTROMS) OF 26-165 IN COMPLEX WITH ZN(2+)</scope>
        <scope>DISULFIDE BONDS</scope>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943155">
        <property type="protein sequence ID" value="AQA29326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761037.1">
        <property type="nucleotide sequence ID" value="XM_047903598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXT8"/>
    <dbReference type="GeneID" id="71984328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04450"/>
    <dbReference type="OrthoDB" id="2831684at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573475" evidence="1">
        <location>
            <begin position="18"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="404"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQA29326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="56227" checksum="F3FE6138659DF4BC" modified="2017-04-12" version="1">MWSPLLLLPIGASLTYQSPLIVERQNPAFTISVAQNTPNGVSDIVDKGFPAFAMSGHSFHEYTGTKANPNVFSRNLLQSISDRTGQPVHIRVGGTSADFARYSPTQTQPIVFPPGYTPGAIPKGMTIGPSWFEGFANFPNVRWTFMSKLANYGRDQSAQDTVTVVRQALRNIPSGNLDALEVGNEIGYYPCANRDCTYNMPAYINEWRAVSGAIDSAVGAQKYQAPALYGNGGIWTVGNAFDKGQNSKGNIVSAAVHHYMDDKPVTVAQLQSNYMNHTRIARQLSQYSAPVSYLKTNQPNVRLHLAEDNSNTFSKDNADVLGVFGSTLWLADYMLFASTLGIARHNIQQSTGFSYSSWRAVNYDGKAAAVLPPWYAHPFVADVLGNTNDVRIADLKLGRDLFSAYGIYNAGTGKIQKIVLINLKDYATSHGTRPSQTVTLNVNNANYNNNVRVEKLTAPDARTQDASKITWKGTSWTFASQGKPVQGISDTTTVRASRGQFTVTVPAAQAVLLTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4G1</accession>
    <name>A0A9Q8L4G1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cx9C motif-containing protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CMC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755112.1">
        <property type="nucleotide sequence ID" value="XM_047900265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4G1"/>
    <dbReference type="GeneID" id="71980995"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01117"/>
    <dbReference type="OrthoDB" id="13601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027179">
        <property type="entry name" value="CMC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590:SF0">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08991">
        <property type="entry name" value="CMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627179-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO10746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="98" mass="10883" checksum="63521096791BA00E" modified="2023-09-13" version="1">MVLSISRDPFVSMADCPQASEPKEGLKSYPACHSQACAIQDCIQKNDYKEEKCQKQVDALYACCNLFYKENGDGASTVSCPKANLLRLKMKQRSNGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4W8</accession>
    <name>A0A9Q8L4W8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02253</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755296.1">
        <property type="nucleotide sequence ID" value="XM_047901401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4W8"/>
    <dbReference type="GeneID" id="71982131"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02253"/>
    <dbReference type="OMA" id="CCYWSPA"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO10930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="708" mass="79320" checksum="D3C1D5599256682E" modified="2023-09-13" version="1">MTRYHFAGPASSSSAPIDLSEDDGDIQILFDRINLNDVKDTIDLSADDDDNLRQLTPGEVGRFQVKARSTAAPLGVPPGYRKQNSATTPTGVTIRPGTNVELDDGDFARITQVVKHHFTGELLARGILLRRTRRVNKFFKKSRNELSVVIQLPDDTTDDSNPSLDSSLIDVPLASIIQLRTIIFTNMTFPDLSYRHSGRVYKNNEQVEDQAELVVRWKYVEYYSLKDQRVKAGTIMHLTETEADMNKSTSDVAKYLKWREQESPQKLRSSASTAAKPHSKKATTVKSEPPTDAFVDLTMDEPESSTARKRNFEAIYVPSDSEEEITEEQQETIMREIKKRRNRDGVFTKRSESVSTITTYTVRKTKSISGPSSTRDRHDSLSGLAEEDSYTFGDFCAGAGGMSRSAEQAGLKHSFLLDHWEDACRTLRLNFPCARVLEQDIFAFCTGGNSASWMRVDVIHISFPCQTYSAAHTRPIGTCPNDDANEATGYSVGPILKLTRPRVVTFEQTEGLFSRHPDSFAALIEQLTAMNYNVRWRVLQCDRYGNVQPRKRLFVIASCPGAPLPPFPQPTHGDGPGLQRPVTIKNRLDMVRPGMDSHDQHMRKHGNRKGAPYNPNKPLKQCITTGGGEGDLHPNGERTFTMRELACLAGFPAHHKFAYSKAMDVIRRQIGNAVPSMVGKVIFEEMVKSMREHDKVVAAWKPEYIGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5J1</accession>
    <name>A0A9Q8L5J1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6590 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755568.1">
        <property type="nucleotide sequence ID" value="XM_047901386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5J1"/>
    <dbReference type="GeneID" id="71982116"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02238"/>
    <dbReference type="OrthoDB" id="3438983at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046497">
        <property type="entry name" value="DUF6590"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20233">
        <property type="entry name" value="DUF6590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6590" evidence="2">
        <location>
            <begin position="259"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="47541" checksum="F87E64353BCC3E2E" modified="2023-09-13" version="1">MHQEGSPMHNYARSIAALRSATSQKPTRIEDMPGNFGDTQNRQGGAWNNGPPTNGSIAPAAAHPAAAAPRPTVGFGNTMPQRPSSLHPGAVGRPVGTAYRPRPSQVGQGRRGPPSQTPGQLGGGFRAPPSQNGGGFPGARPNLAGGPRPVPQTQPARPQPPPQSQVGQPQAPAVGINDLPQVFQNLNLGMYSNVPAAPAGATSSILPYPLPPQSKLTTFPVRPTNAPTGWSTNYPMANSKRYKWFVNNVCFKSPYKRWTFDKGDVIAVPYHVANMNENLDIAAANGGCRETKFGPILSKQRMCIVLWKHHECMTCLPLYSHGHRGIAAKQGDREEDYIEVLDLALKSTFIPQGSKKPLEHIHWSHPHGYLTADTICHLTGAMKVSWQEPILHLGRVTKLSYDSLVKYHKALMRKAELEKPDKEWPAAGVNPKISHDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5R1</accession>
    <name>A0A9Q8L5R1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755680.1">
        <property type="nucleotide sequence ID" value="XM_047899290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5R1"/>
    <dbReference type="GeneID" id="71980020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00142"/>
    <dbReference type="OrthoDB" id="3647985at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="16877" checksum="33777C6EBBD2361C" modified="2023-09-13" version="1">MDSLPIELLVEIADFCDHPSQKALRVVSKDFRHVATPFVFEQVYLAMLQEPLANFESIAGSNHLAKHVKKVTFFCDIMTDFDCIEKYAMSLELKPDFTTWLEHDIRLGGQGEWQEWKAVPGQTLSARDIESGWEVYTRLWREQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L696</accession>
    <name>A0A9Q8L696_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756012.1">
        <property type="nucleotide sequence ID" value="XM_047900753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L696"/>
    <dbReference type="GeneID" id="71981483"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01605"/>
    <dbReference type="OMA" id="MDFTRYR"/>
    <dbReference type="OrthoDB" id="67716at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056548">
        <property type="entry name" value="HEAT_Nup120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048884">
        <property type="entry name" value="Nup120_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23300">
        <property type="entry name" value="HEAT_Nup120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21486">
        <property type="entry name" value="NUP120_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="5">
        <location>
            <begin position="77"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup120 helical" evidence="6">
        <location>
            <begin position="679"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin nup120-like HEAT repeat" evidence="7">
        <location>
            <begin position="891"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1251" mass="141262" checksum="A48BB772DA3FFF54" modified="2023-09-13" version="1">MSAAPVLYQETRLSLDSASPSSILNINTATNSFSASFGAGRKRPFDDISGLDEESYARKHLASEGSVFFRPKSKAPRSFLWRVLDERQLLEVQCVDLVLDANKHAKAESWLTFHIALPAPIIPGGVALADAEEKDALEVFVITSDKELYTVTLRRDLLVRETVPTDFDAATCVKRFGLNLVSYRRPYRLQAVGSLELLLSLSDGSILRLTRQPNENAAQWRETQYSEGGWKGTLKRGLPFTKTQTVRYDNHDLNADTVAAMAKSPNGRFIWTLGLDHILKAWDMESGKVAMTRSLVGAGADEDEHNKNNRYIMSAEQGTLLQIVSAPDAANSQALATPNTEVPYYLIAYSPKDHEFKFFGVRSGRDGEGIEDVHLDDMHRGEKLIPPIDDLMNTNIWHMEHFAFSPGENFSGAQLWLRVRSGAVCRTFMLNFDLLDQDGAAIDLEDVFASGWSAVDSSSLTVDKLKSSVDFIAATGSQDMSRTPSEKWLNFLFFPGRFSQASLESALYLYCKGRNLPTSTSRGIRTNEQPLKERITGAVAAKILLRRLPSNDRPDYESYQRDLQTQWETFYSLLTHLHNRRHEAVGFAFDLEECLPWAICADFVAPMRANSGFENLTLNADLIMSGDINETHDNVRGRIIETDEDIARSQFLALARRCRSCFAAAPQSKLRSIAIANAMAQTPDETAEEGMRSIYDRCNFQEEIGELEYNILNDLSDELNGLGGLNDDHFLAITERIEDKPANDRGVDRELLGRLGRPFSVAVAQETLQRSQAILLDMLTLLVFLHCDLQEDELSEELRPAQVYENLMMHLRHVELRLWLVSNIRIEKKQAGGRRSEQLTLYEHMFAQDWRAKPDRENVSHGLSELLTAWSKNWIFGINISHDYDRLCGHILADLVEHHDIDLASDFLQISPDTAWISYLKGRLYVLNGEYELAGLAFHEAANEMATMAPDENSLLTMEEKPFFAKGLASYYHHVSSLFDKLKVFASTAEFAQLALHELPPDNELHRSLRTIDKRKKSDLDSPAPQRIDDAMEELHLIRNKEHKDELRLRLFNSLNSIGRSHHAYKILLEIDNYQLQKSSLRTILDTCIKRDAVSTLLELPIAGDLAKQADTILLELAKKSMTSGLPSGPAYHKILFAFRTQNNNYRGAAAILYDHLERLRKSSKLAIQDPDDETLVQIYVLLVNTLACCGEGEAWLLADPIPHVHEPERQRKLVTISDIRREYTAELDRRSEIMHGRFPLMGGGDDMDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6X8</accession>
    <name>A0A9Q8L6X8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin structure-remodeling complex subunit sfh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756295.1">
        <property type="nucleotide sequence ID" value="XM_047901080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6X8"/>
    <dbReference type="GeneID" id="71981810"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01932"/>
    <dbReference type="OMA" id="VEVQGIW"/>
    <dbReference type="OrthoDB" id="10258327at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="503"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="617"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="757"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="776" mass="85117" checksum="51D897822DDCABF3" modified="2023-09-13" version="1">MSAVNSTRVNAPQAFVSSFAPRIRTYGNSLLTPVVPQTILPPVRTTKRGTTAINYAEEFDDDSIDESDGPRRATGLRTAQQRREPDPLAEKAKELGKDIYAPVDVQGIWRDWMGKPKRILTERQMHVQSALPTTLIPIKIDLEVAPFRPEAALPTPNNAKDFGIDENLPAYKAPEPTPPYRLKDQFLWNLHEALITPDMFAKTFVDELDFPVMRKQAMIVEIAQQIRLQLEEHAATALHPLFQPEAANPAPPTTNAPTPSLRPAMSREHSSTPLQAETPNGAFLQLPLTNGHNTSSDPPSPMANGLSTSALAVTAQPLPKDPSASSALNPPDTHRCIITLSINHQNKLYTDKFEWSLLHPPGFPEVFAKQTCADLGLPGEWVPNMAHAIYEASLRLKKDMIDNNGTLAGVVGSGVDGWGVIENEACEYHGTAESALGVGAGWRFDEDGLGVDWEPKLEVLSKDEIERREGDRERQIRRQRRETARFTTNYSLQAQSSGLGDYFSGGLGASQTNGGADDERMGRGERAKKKRRFRSLSPAGRETPEVAGFGGTTSQLSEGERQYWSCSHCCIWGAAIWGVRDGPAGPRTLCNNCGLLYERDKRLPPWNHRLFYHEKNQGSREAHMPQFGPGAAAPPPRQSTHLQSDIASFPTLTPTQTPRSLREDLNPSSHLYTGASSGGQGQISASTMADIVNYAEPGEDLDWTKITEPRERKRLQNIINGRKYRERRLAAEGHGGSGGNYPGAAGVGSFLSAGYGQRQSTLQQTPSAISIDSPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L738</accession>
    <name>A0A9Q8L738_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00461</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756433.1">
        <property type="nucleotide sequence ID" value="XM_047899609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L738"/>
    <dbReference type="GeneID" id="71980339"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00461"/>
    <dbReference type="OrthoDB" id="10264412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.830">
        <property type="entry name" value="Ile-tRNA synthetase CP2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="86"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="810"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="719"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO12067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1098" mass="121505" checksum="4E64B65E409E121D" modified="2023-09-13" version="1">MSAISPSRILRAASHDNRALLDKIREVAQHKDNWSDTLSLPKSKFPPRPSAEQIESARQRCADDLYAWQRANRPRTIVRERDGTSEEIDNEFVLHDGPPYANGAVHVGHALNKVLKDLMLRTELGRGKRVQYRPGWDCHGLPIELKALQQPKSPGKGAKAMKDSPGQEAKAAAAASSQMTATDIRAAARKLAGETIEVQKKSFREWGVMGEWDAPYKTMDKDFEMRQLGVFNEMVRKGLISRHHRPVYWSPSSRTALAEAELEYDDNHQCAAAFVKLPFTRLPKILKQHPLVSSGNMGALIWTTTPWTLPANKAIAVKDDIDYVVAEISSVSDEDTPKEQVVVAKDRIEHVQSHLPEGHIISPLTEAIPGAKLADGNSACYNLFTATASPILQADFVTATSGTGLVHMAPGHGMEDYQVCQQQGVGPALAPVDDEGRYTSEAFPAGNSEAFTGLDVQTQGVQAVLDVLKSPSLFIPKDVSHSHGSLLLAAHKFIHKNPIDWRTKQPVIVRATAQWFADASAMKDRALAALDDVTFIPESGKKRLRSFVEGRSKWCISRQRAWGVPIPALYNVETGEACITDESINHIITIIDERGIDAWFSDPVDEASWLHSSLEPEKWIRGKDTMDVWFDSGTTWTSLQNRHQGGHLSDVYVEGTDQHRGWFQSSLLTAVATQDSNNKPMASFKLLTTHGFTLDGDGRKMSKSLGNVISPDEIISGSLLSAPRGKNKNKAKKPAPTGSKTASMGPDILRLWVASSDYTRDVSISQPVLQSVQQALNKYRITFKFLLGVLHDYPTHSPDVNLLSELDFADKVVLHQLARCSKSVFDYSGEYKFYAAINEINKFVNNELSAFYFEIIKDRCYTGTTSVRRHTQTVLLVIMQELMKMLAPVTPHLIEEIWAWSPEQMTRLPGGTAQDLSLHPLRQIWKQPLDVSTLGLDSAEQLDEALELFRSINSAVKLAQEGARGARKLGNGLASEVEIYLPDSLLSSKSGSWLKQNDLAGLLVVSKATVYSTSDHKADSGNVAEVGEESWHYSRPIVYSTGQATELGSEMRVVVVPPEHEKCVRCWKYTAEEKTVPCSQCVEALAEGYIDNHLPTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7F1</accession>
    <name>A0A9Q8L7F1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
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    </evidence>
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    <sequence length="150" mass="16304" checksum="B8BAD610FE7B9AE9" modified="2023-09-13" version="1">MRNHLQFCTTGPRVASLVTAPFRLVVQTGGVEGLARLTNNAHDSRYWWSLSQTENHDNLIVEYSTAATHSISIIFFHFSPSSFPLSGPQLQVPPRRAASTGPARPLQVVHHWHCTGAHNRGASTPTGADQQRQSVECGRAQPSAVAVAVE</sequence>
</entry>
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7892" evidence="3">
        <location>
            <begin position="843"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1134"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1401"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1427" mass="158533" checksum="E6E989095B2B5F8A" modified="2023-09-13" version="1">MDYANGRSASEAPSDDEDFYGDDTPTCPTLDHQPTQENHPQENHTQEEPAAATVATATTATATTNPEAVNGDDEDDESSSEMDFSSPSRPSTPEPATLPAASPTAHAGAKRKLSDATDANNVAPVPTQESAKKRKLSTASAKQDGEKPRIPQLPAEVWQRVFVHLPPAMLCRCLRVCKSFNQWLTSTSAPPTARKDTPKIQVLDSESIWTNSRKTFFPTLPRPLAQFSELGMLKLVGGRSCQFCHRPPVPSPATTVLNAGPGPNGLRVIWPFGIRSCGLCLQPRSLKDVQVLGDPSLGRLRNGVTHGYLSPDLHFAAESVRQTVPGGIPGNLRFSKIYHITDLEAIRSEEESARALGPGAVDEWHKGLFARGKESMADSARWEKWELQQLRPGQDLAQVLREYDLESFPRHGEEAQRRSVGVNGVQSSPTANGIHPLPQPVHFFHNGYNNHFQPPPQPAPQPPQHYLPPPPPFPAPMPPQHFFRPVRNPQEVEEARQARKAEIERRCREFEPPLEPNVLQHMESFQAAMQITTPMTDPAWEMLKPRIIAQREGAELAEHERASQLAALQAALPSGNMDDIVPRPAKETYDRDYEQAQEPLRKQLGEYADDYINGKWGGGKMLDKDNAPLFALHALMHIRQRYAEDKSLGLLPRFEPPKRKDGAKQGSPPVEPFLSLDNMKWVYDNKVRPLTDVHRREHFICVGCAEEKKPKWFAFEGLIQHYGAKHTTAFSRGNIVVHWQTAEWPEEPPFHTNPSHWLKLDRRPQDYRNNNRARNITPHGNHESPLSAPSSAPTLPEKPYHAAINGYPVVSPGYPPHYTPPASAPSNGYFYPPGAADSNIDMSHDAQVGKLSSDARELWDALDGVKDMMECIRIHTVIHLTVTRFAERFRQKPHLDLLTDALATNALMRPLKNAHGLACRSCVAAQPNGVGNHGSYWIRIKGVKVYNTSSLITHLKVMHQSQVQSGFLDWTRDMIELPEVPLVKDLLRAPGMNDDKLALVAAAFPRAFPAPLPKIGVVSEEPAHANAGGLPASRLLTRLGKKQKAQARKKGAKQPNGVTDRDDSQEPLPEPTEDEYDPRRPMFVAPKEQVADPSQFDTDARKKSPPAVASGAGILDLTPETLAALQSLGVLPVQQQPQPAPQNDRSSRSPSVGRDEPNLPSQAVSNTSVTTPTEAPDIAAILASLTGQAAPTAPATTPKAASNRSGSVPRRYQHDQHRRSGHEAVARQHRDDQRPSSRYEPAPTTSHDTSGLDLRALQAALAQNGQHFEQNQQQQRHTYVDAPYQPMPRYQYVYEGEQHCSQPQAHAPAYREAPVQYMPLPEREPARYQYEQPAPPKPIYVDQYGRPLELIPIDSAPAPVQYAPNPYEPQQYGRRHEHPMYTTTMAPGPHLQPVYDDRRQMYYEPVPPNGTAQHYTYDDARASVPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8T6</accession>
    <name>A0A9Q8L8T6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00361</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756659.1">
        <property type="nucleotide sequence ID" value="XM_047899509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8T6"/>
    <dbReference type="GeneID" id="71980239"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00361"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF64">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="590"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="66907" checksum="9BEAA305005334E0" modified="2023-09-13" version="1">MYVHRSLSATEMTAGMQDLATRPSRIAWHRALDDDEEMKFGVLPAYAVATLLQITTAQFITAPKDLITTTGNGYPVRYKEVPSGICETVEGVKSYSGYIDVAEDQHLFFWFFEARNENPKKAPLTLWLNGGPGDPSMVGLFSSNGPCSIDYDGNVQFNQYSWSNVSNMLYLDQPTTTGLSYSEPVNAYTSENGHIITLPNDVCPEAAPVDSCGTLSSSNASLTANSTTNAAPNVYKALQGFTGAFPDYASNGIHISTESYGGHYGPVFADYIAEQNAKNHTGNAHMELRGLSVGDGWFDPVIQFQAYYNFTVSPGNTFDFKPFNESMEKQMYNALYGEGNCLDQLLDCNAGGIDSVCSAADNLCYDDVQYLYDAVTGRDEYDLRELSPDPFPPTSFVAYLNKPEVQEAIGAFTNFSYSTTNLGSGTVATADDQEARRAGGHLHIVHYAGDADYNCNWLGGEAVATFINANNDNSTHAGYENVTTPDGIVHGVAKQSGKYSFVRIYDAGHQVPFYKPAAALAVFERMVRQVDIPTGEEGNLGYVSVGPERSRYRNDPATVQEEVLDAGCGFVEKTNLPVRPEDGAGRRRGGGGGGGDRDGVGGGGSEVEDLFCDLFLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L994</accession>
    <name>A0A9Q8L994_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757646.1">
        <property type="nucleotide sequence ID" value="XM_047902003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L994"/>
    <dbReference type="GeneID" id="71982733"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02855"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="96" mass="10714" checksum="EC0058D392FC71B6" modified="2023-09-13" version="1">MRLLALLPRNTLLSFSAVSNVPVDESMFSLLLTQQQKLAELVLGPVTFNCVPLLSSGYFGDALWSTLHSLAIPEVIGSKDDLHAYWYMLQRCSELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAC8</accession>
    <name>A0A9Q8LAC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 monooxygenase atnE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_03167</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757454.1">
        <property type="nucleotide sequence ID" value="XM_047902315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAC8"/>
    <dbReference type="GeneID" id="71983045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03167"/>
    <dbReference type="OMA" id="NICGQMP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
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    </dbReference>
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        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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        <location>
            <position position="528"/>
        </location>
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        </ligand>
        <ligandPart>
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        </ligandPart>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="599" mass="67236" checksum="12F3C6812C771B3B" modified="2023-09-13" version="1">MANLPSIAEMRQFAYATVEKLPETTQRLLQAIASTSEQLHHVLAKGSHYCHELMSSRPELAGLLGTCTNSFQCLSSMAILGVLVATIAAYVVYQLYFHPLANYPGPLLGRLTQWYNVYHAYVGDKHILFYHLHQKHGTVVRFSPNSLSINDPVALKTIYAHGANVQKSVFYKCFRAAPQAISTLLATEKQHHARKRRIMGQAFSDTALRGFEQYVLGHTQDLVDRIGGVVGGSGLEKAGWSAPLDMANWCNWLVFDIMGDLVFGRSFGTLGEKPENRQGIFLLGRAARRNYTVAAMPALLYTRLEEYLPLLRGLYQDRCKYLAFGKKQVMERTKEQGQNGSPVVETGRRDIFSFLLHAKDPESGEGMPMPELWMEGNTLIVAGSDTTSTTLAATLYYLLHNPNTLTRLEREIRSTFTSSTEICTGPRMQSCTYLRACIDESMRLTPAVGGVLPREVLKGGLSIPSLGLHVPSGIDVGVPIYAIHHHSEYVIEPFKFDPSRWLGEKGHPQDKEALHAVFNPFSIGHRACLGKPLVYMELNIAIARLVWEYDTRLSEEQHVSGFIKKEIGTGKRQPGEYQLQDWFMSRNEGPWAEFRRREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAI3</accession>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO13867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27273" checksum="11EB0A855A5A1950" modified="2023-09-13" version="1">MDAFSTSEASTQVANTYELVENILIQLREISPASVVKSQAVSKTFQHVYARSHQLQTCLPMHSSVDSRGSERGLKIEPLPKIFADTCVAWPEPFGAGWEYKLAFEIDSQELASGRWREGGSWRPWLVCRSSTTTIKAVVDGIGEHNPGGVTTNGGYDISLNLDCKTGITFGQLVDAAHELADLDGKAPYLQVDFKVMTDHEGRPVSKEAFSLKGRRSIGFRKAMDSAWQIKKLWDGFEPYGVEKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBB1</accession>
    <name>A0A9Q8LBB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_03754</name>
    </gene>
    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902902.1"/>
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    <dbReference type="GeneID" id="71983632"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03754"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="193"/>
        </location>
    </feature>
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        <location>
            <begin position="312"/>
            <end position="365"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
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        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="415" mass="47168" checksum="284F09FE19817408" modified="2023-09-13" version="1">MATSPQSSRMPSHYEFRKSKKRPADTAAEAPAPAKLVKTDLKLDIKGAAERVKQSSRPSASANTTNKNVFEQRDKTLRAEKKPATPSERPTSDKRAIAGLTRAPAHPRVTQKRDVPPNIISDTKATAKHVGTQRKLKSAMKKSSDASGPRPKKRAKFKEEEPADLDPDDLEPSFPPPMFTPQAPPGYPPEIRDPTDKIQFLEYQVEYLKKHPPEEKIWALEAIIEGLLDDLANNARLKPLLKTAKAEEWKLREACDDRVANERVRFEKRLAEATEAFEKKTSIKTEANSRLQKKYLDLKEEMRALQNSNAELRAQQTDQQEKQNAANTKGQQKMQHLEEKLALSQQQNQHLKEQDALSQQQIEHQETKTALRDAYNAQLKEFIVKAEKQVPTPVRVYKGWDSTFSVEKILAWMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCL0</accession>
    <name>A0A9Q8LCL0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gibberellin cluster GA4 desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759371.1">
        <property type="nucleotide sequence ID" value="XM_047907887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCL0"/>
    <dbReference type="GeneID" id="71988617"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08739"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="39070" checksum="CDA200DA0A35E91F" modified="2023-09-13" version="1">MGEAESQHTYGIFRFCEPDLSVPAEERAIFAGPANIRAAEEKIQLRDFSTSNDIAKGAEGLDVQAFTYIKHKSSLAGEELLQGTNAEDIYAPEAIDLILKLTGAARGVVHNLTFRREAATRQADINHVIKAGGERDQAIKALPQDRIFVVGRDTSSSDEPSREAHCDMTLESLRDTLTMCRKDVSEFAKPVAEAIAMRAQGAVVRVPRYAAYSVWVRLSLLSRTSTPECSQANCITSVPSRPSNATPLQSSTTAASIHPSLPITTFRVPSAVTENGEYIVKAWLHGPPRDPEKLKWYWMPNQTPEDVCIIKFSDSASEEDPNTAAGCIHCSPIVLGTENEEVRQSVECWVYAFWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCS9</accession>
    <name>A0A9Q8LCS9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759522.1">
        <property type="nucleotide sequence ID" value="XM_047907027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCS9"/>
    <dbReference type="GeneID" id="71987757"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07879"/>
    <dbReference type="OMA" id="ATISQFV"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040268397" evidence="8">
        <location>
            <begin position="19"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="73"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="45067" checksum="8B6CD96BBC4576CC" modified="2023-09-13" version="1">MKFTTTQALLALAPLASAFPAAVYEALQNDPAVQARTAEILAERQLSADSATALFEANPTFSESQLIDVGPGSGHEYTAPGPNDIRGPCPGLNAFANHGFLPKSGYATITQFIDVTTNVVGMGPILAAFLAVLGAVLDGSGTAWSIGGPPPASVGGLALLGRGNGLTGSHNKYESDASPTKPDLYESGNNYETMVDQFQQLIDISPGGFVDLNTLAKHRSNRFDTQIKNNPYFFNGPFTGVLVQPAAYTFIYRFMANHSAENPVGELSYDVIKDWFGITGESGSFVANQGQERIPLNWYRRSLTAPYESTYFLADAAAAGAIYPKFFNVGGNTGTKDSFSGVDVSDLSGGLFNSASLAQGNNFACFAMQFAVQAKPDILLGPLTQLTSALGSLTSALACPQLTSIDEAQLERFPGYQKSTQDGITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD41</accession>
    <name>A0A9Q8LD41_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759390.1">
        <property type="nucleotide sequence ID" value="XM_047907406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD41"/>
    <dbReference type="GeneID" id="71988136"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08258"/>
    <dbReference type="OMA" id="EDRICAR"/>
    <dbReference type="OrthoDB" id="3650782at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="28903" checksum="C4B69CEF58A5B3FC" modified="2023-09-13" version="1">MASDHSKRDIFPFFDLPREMRDSIYLHLGISSSKTRLMHNDGWDPDDEDSKKPIEDLSVIRLRIENVCRSNVLCVSRQFKQEYEEQLSKATTIVFTDHKGNEVWKLLDMSDKKFGDVKQAKYYGYIQCTQCPDGPQSCQVGSDIDDTIAWLQVTLGHLATSSKVTIVVVLRWSGSMDLRWPQSPHRAHLEVDFKKLASVPRVSAIEVYRDNSGVDDFDVEAQVLAENLYVSWTAKDGWQAPVAAANAMEESKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDA9</accession>
    <name>A0A9Q8LDA9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08347</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759703.1">
        <property type="nucleotide sequence ID" value="XM_047907495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDA9"/>
    <dbReference type="GeneID" id="71988225"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08347"/>
    <dbReference type="OMA" id="CAYGHLK"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040267539" evidence="8">
        <location>
            <begin position="22"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="68"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="450" mass="48724" checksum="0B272DCC983B2856" modified="2023-09-13" version="1">MFNKLTTAVALLESSSVLVSAFPHIAQQVAEQKRQSIPTVPFPEFPGSPLHALYNKFDPESQLVSTSGEHEWRAPGPGDIRGPCAGLNAAANHGYLPRDGIADSQSINTGLWEAFGLDHTATIFLQTATMFFDGDPLSGRWSIGYHSDKTNSLGLIGDILGNQTGICAYGHLKTEGDASITRGDWLAPTQNSNCASYPEFAQELLDLAKARTGGNLTPQVLAEHQYNRKQHSIATNPNYFSPAYAGVAFTFGAHMFAYELLANHSAEEPRGFLTPEVFESFFSYTRDANNQLVFTYGHERIPDNWYRRANDDAWTLADIGISTAQQCASYPSNCQVGGNTGEVNSFSGVDAGDISGGLLNSFEDLSDPDRAMCFIAQAIQADVPSFLDNVFTGVALQKVLAMIPTTLIPAISPFMLTCPNLPAGKSVLSYGQAYPGMLAKQQGQRNPYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDD9</accession>
    <name>A0A9Q8LDD9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="4 14">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_08701</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the sequential decarboxylation of four acetate groups of uroporphyrinogen-III (octacarboxyporphyrin) to yield coproporphyrinogen-III (tetracarboxyporphyrin) with the formation of intermediate hepta-, hexa- and penta-carboxylate porphyrinogens in the heme biosynthesis pathway. Acts on a number of porphyrinogens, but only coproporphyrinogen III can ultimately be converted to heme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:31239"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62626"/>
            <dbReference type="ChEBI" id="CHEBI:62631"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 14"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759852.1">
        <property type="nucleotide sequence ID" value="XM_047907849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDD9"/>
    <dbReference type="GeneID" id="71988579"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08701"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000004">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="16">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO15486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="372" mass="41943" checksum="BECEE1E870333E09" modified="2023-09-13" version="1">MADLFHDFPPLRNDLLLRTARGEKVERPPCWVMRQAGRYLPEYHQEKGQHDFFECCRSPEIASNLTLQPIDRFEGLIDAAIIFSDILVIPQAMGMEVVMVDGKGPHFPEPLGSPEDKQYGEVMGRDVDVKVSLSYVYEAITMTRKKLDGRVPLYGFCGAPFTLLCYMVEGGGTKVFKQTKTWIYRYGKESKALLQKIAELCVEYLAHQVIAGAQIVQIFDSWAGELSPTTFQEFSLPYLNWICDHLPARLQELGQERVPMVVFAKGAWYAVEELCQTKYDIVGLDWLHEPKEAYAIAQKHGKVLQGNADPGVLYGGHEAITKVVKNMVDGFGGGKQGWIANLGHGITPWVNPDDLKFYFQEIHRLSGEYSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE15</accession>
    <name>A0A9Q8LE15_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Het-C-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760059.1">
        <property type="nucleotide sequence ID" value="XM_047903505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE15"/>
    <dbReference type="GeneID" id="71984235"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04357"/>
    <dbReference type="OrthoDB" id="2506204at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335247" description="Het-C-domain-containing protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="685"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="595"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="794"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="892"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="930"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="955"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="973"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1001" mass="111658" checksum="8401C90C36EE9503" modified="2023-09-13" version="1">MAIKYGSWLPILALCLVLYARPTHAFGAGNIGSTSKIEGQNWRHGDIEDTLLTLLTARAMGGEKFSKLDVKRVYFGNWLRDYSQAVDVGTVKYVSAEAIRLLLWILGFMSFGYGTGEFEVTKERLGVYRPEEHIDNPRDYADNLDARQYDRRLRGPVDERRELGIDEQTGLKHYIASEQQGITTSAGMIRGLFRRSIELGRRYKESRDTRDFYEALRLLGTGCHCLEDYSAHSNYTELALIELGERNVFPHVGRDTQVRLQGARQPVYPIVTGTFGGVDFLHSVMGEFSDKATQSELQELEGTIQQSQNADTSMLKDLLDKLPSGILGDDDHKNKADQLQANAQAAQMENMHISPKDPEEFTQQMEEISKQIYPIMEFHDNLMKSISEAIDKIPVLPDLIEEIQNQVSLFVFSLLAPFVVPIINQVKNELRTGSSEIIQSSVEKQLIVFRDDRSSDPTHSMLSKDHFSNVLNEPAGKIASQVLKWVVPQIVQAWDNDDVDIRRTNDRIIAGVFHHPALREYGNDGASDGRLQMFGVVEKWWGEMSERERDDLRNKLSRSGVEQGRNHKPGVHDGGHGSCKPLGLPNSGHGNSSGAMGGALGGLNQALGGGSSSGGRQGKQVQSKISDTVGDAVGGGALGSIVGGVAGAVGAGLLGGAFGGDKSEKKTYKHDEYEQDGSYNTRITETGHRPGGYGQEERYGQAQMSQTQFSSGGYQETYQRYEQDGRQCSTDYGYQQTHEVRPTHDGGYQERTERRYEHPGGRYEGEVTEQRVTSSGRQYGGSEAYSGRKKKDDSDDDDDDDSNDDDDYEKKQKKQRKKEEKRRKKEREEEERRGGYGRRNSGSRERRKSKSRSRERRDSNEHKRQSGGYKRQSGGYQSERRDEYSSQSSYSRQEHSSESRFESSSSYGDGRQEYGSSGRGGGRQEYDGSQGYGGGQQEYGGGRQEYGGGQQEYGGGRRNDEDEYQRRDDNMPGGFGGSSGYGEQGGSGDGYSGGGYQERRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE98</accession>
    <name>A0A9Q8LE98_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759990.1">
        <property type="nucleotide sequence ID" value="XM_047906951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE98"/>
    <dbReference type="GeneID" id="71987681"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07803"/>
    <dbReference type="OrthoDB" id="3648975at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="36116" checksum="6EF85D691249AC29" modified="2023-09-13" version="1">MSRPGATTMLGLLYEGSDFEAWKERLRGLLQQQDLDLDHLTQNPHNYDAASRRNIIIRASVSESVLTRLRTPAIWSVPTGPLLKILKRRAQPFRFLDLPAELRNHIYELALPHSSVAHGSQRHAKSGLPALLHTSSKIRRETLSIYFEQAVFRFVIPRSPEEGPGIESTVQHIKTWAKVVVREHVTHLRHVELLQDVRVADDLHISAHLDTNRGLGYCYGGPAYLDDAIMQHTSETRNRKEVKGEDIIAMLTTNLELWKRTTTLPTAEELLSSVPPEGISLPKFRAMFRGQGVGTTIGSEDLVNSVLAYHRASKLVFHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEW7</accession>
    <name>A0A9Q8LEW7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760473.1">
        <property type="nucleotide sequence ID" value="XM_047904526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEW7"/>
    <dbReference type="GeneID" id="71985256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05378"/>
    <dbReference type="OMA" id="GRQIWWG"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="34839" checksum="ED39BEEA29923BE0" modified="2023-09-13" version="1">MDSYFYPDRFSPIMVRDEARQRERHARNIGQIEGYGAAIRDMRGAQMRERMRPLLPEPKPEEKKSKSRKTTTSSPQKTQTTRESNTTGSKSKPTVSTSKTTQTGSKPKTTTSTSKTTQTAQDKYKQYKSTKGKSKETGSSEAPTTRDDFEKYQQYKKKHYEYRELLQQDGDLKSKKTHEKRSQSKKDSTRDSKKDTRGRWDSVEESEYRIQPKDSSDLRREKAERERERAVYYEQQLQKEQDRRYAAEQWQRQRLDVAERNYRGYGVVDVPRVRPGRRRLAAIPGQGRQIWWGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY6</accession>
    <name>A0A9Q8LEY6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Trehalose phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760350.1">
        <property type="nucleotide sequence ID" value="XM_047903974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEY6"/>
    <dbReference type="GeneID" id="71984704"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04826"/>
    <dbReference type="OrthoDB" id="937291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052078">
        <property type="entry name" value="Trehalose_Metab_GTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049438">
        <property type="entry name" value="TreT_GT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47779">
        <property type="entry name" value="SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47779:SF1">
        <property type="entry name" value="SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21269">
        <property type="entry name" value="TreT_GT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Trehalose synthase N-terminal" evidence="9">
        <location>
            <begin position="245"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="8">
        <location>
            <begin position="461"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="701" mass="78731" checksum="02C5C0DA1D08AA87" modified="2023-09-13" version="1">MDSHSSAQASRRSSHAAANNGATAKHEFQAVAPTRHIERQQRLREKKHELGIALSEIFLGIAIERKSDSKVDIGFACHDGTYSIDFAGHTLRTDGTDSHGDRAACPTKLPEDYEATNSYTFVGVGLSQEVLDINPQIAPRLWLELDIVPLLIKVEEGGSLHTASQIDGVDELADSMARKCLMFFGPSFQPRVQVGFSNKVEVDLANRARLTSIEDYKRTVSERTWSAVTKYAAALKERKVKIAFFSATPQGGWVALMRHALIRFYTLLGVDCTWWVPKPKPEIFRITKTNHNILQAVAGDDERLSDEQASAIHDWVQMNADRFWLRDKGPLQPRSEGGADVIIVDDPQMPNIVDISKKADPEHPVIFRSHIQIQADLADTPGTPTAGVWDWLWQSVKHADLFIAHPVSAFVPKHVNRRALAYMPATTDWLDGLNKEIRDFGNEYYLHEFNTECVRQRMNTLQYPKRDYIVQIARFDPSKGIPDVLASYAELRRNSEHCRDKKADETPQLVVADHYSVDDPDGVRVLNQTLELLDGEYSDIKDSVVVMRLGPTDQLLNVLMQNARVALQLSTREGFEVKVSEGLHKGVPVIVTKAGGIPLQVQPEKSGFLVETGDYKAVAKYLDVLFSDEERYQEMSQFAASHVSDEVGTVGNAVNWMYLADQLSRGERVEPGGRWIWDLVRDLVGEGREEGEVRLPRNWTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFH4</accession>
    <name>A0A9Q8LFH4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760858.1">
        <property type="nucleotide sequence ID" value="XM_047903345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFH4"/>
    <dbReference type="GeneID" id="71984075"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04197"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="14813" checksum="F147CED3B6897173" modified="2023-09-13" version="1">MAFTTMCRVLDIIFCTDVQCFLARRRPKVLKEYYCSNNESGGMSSASTVIDIRKQLRANASRMKDVRIANRCRRTFRQPALAHNARPCPDCQRAHDEAFLALVAQRIQDEEDDFAACMNVINSYWASQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFR3</accession>
    <name>A0A9Q8LFR3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 39 kDa subunit homolog</fullName>
            <shortName evidence="7">eIF-3 39 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TIF34</name>
        <name evidence="9" type="ORF">CLAFUR5_04050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFR3"/>
    <dbReference type="OMA" id="VWFSHNG"/>
    <dbReference type="OrthoDB" id="24966at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000127">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24805">
        <property type="entry name" value="EIF3I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37897" checksum="1E0AE9ACEED593D1" modified="2023-09-13" version="1">MRPILLSGHERALTQVKFSKEGDLLFSVSKDHVICAWYSANGERFGAYKGHQGALWTVDVDPTTTLLASGGADNTIRLWDVKTGKLLKTWEFGTAIKRVEFSEDGKQLLGVTEKRAGQLSTIIVYDINTEELENQPEEQSLRIVVDDIPKVTVAGFSYLNKFLISGHEDGSVSQFDAKTGEELNHTYPHEENSPVTDLQWSQDRTYFITSSKDKTAKLIDAKTLDVLKTYVADTPLNSAAITPEPTQYVILGGGQAAMDVTTTSARQGKFEARFYHKIFEEEIGRVRGHFGPLNYVAVDPTGKCYASGGEDGYVRVHHFDPPYFDFKFEVERERERAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFX5</accession>
    <name>A0A9Q8LFX5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761126.1">
        <property type="nucleotide sequence ID" value="XM_047904267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFX5"/>
    <dbReference type="GeneID" id="71984997"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05119"/>
    <dbReference type="OMA" id="FESHYFI"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF100">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040306991" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="65"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="32750" checksum="24DCA575194837D5" modified="2023-09-13" version="1">MWSLVVFLLATIVTAAAVPLEERQQLEFDYIVVGSGAGGGPLASRLARAGNSVLLFESGDDQGSNHNYSVPGFQAAVTQDSKIAWDVYINHYQHQARARRDPKYVEGKGILYPRAGTLGGCTSHNALIWITPHASDWDNIALITGDSLWSSANVQKYLAEVYEWQPVAPADPAILLKDTMLVQHLAGGAAVMGIGPDPLAAVTGLGGTLLVDPNNTPGRDSLEGFYQIPLIQRGGNRITVRDFIVNTVRLGFPLTVRMNSHVTKVNFDTSSGTPKAVGVDFLDGSHLYRASPLSGASGTPGSARAGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFY9</accession>
    <name>A0A9Q8LFY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761113.1">
        <property type="nucleotide sequence ID" value="XM_047903946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFY9"/>
    <dbReference type="GeneID" id="71984676"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04798"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="45723" checksum="5C2608D90F8FB56A" modified="2023-09-13" version="1">MSSIITTRTWQCAQAHLQRCGARLPARTFAPIALGIRRASIKYIRPAKVTRNRSKYGLIKCKDSAAISINDSDGPSDITEFQKLAEDGEATVQDLRTFLTKTKARLSSLPLANRHDQAAHAGGEKALLWLWEYRLDARKEDLDYRGLFEPLCWLLAAEHNESFVIEWVKKSRQTIADQGVVEGSRDWARHKAWCGNLLGWFIEAKLQWSPHGSVDPALEAMKRIVDALQGTVALRFKMQSVTAISSALTDDDRPPCNAALYEWFIGLRKMTDPREYTRHLDSLFHPASPDPLPYARWASDYYEHPKKPKEEIKKLKALRSVGAFMLRAAYISRLLGDVPTARKMEDLVQEHHPLVWGYRQRIARKANLNLGDLHAKAKVETSALPAVAWRNKSDIVPHNERDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG88</accession>
    <name>A0A9Q8LG88_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761427.1">
        <property type="nucleotide sequence ID" value="XM_047903461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG88"/>
    <dbReference type="GeneID" id="71984191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04313"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="11901" checksum="673940258B6BA83A" modified="2023-09-13" version="1">MPFGTLTRTSLESTTTATPLPSPTTVSGYQLQQQQIKLAIIFGIIGSALAAAAMVLGYLQLRKQSRDQRASTGQSGEVLDTHSQRKIWRRPSFRRCPEELIVRIEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGB5</accession>
    <name>A0A9Q8LGB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LSM complex subunit LSM5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">CLAFUR5_04820</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGB5"/>
    <dbReference type="OMA" id="NNICTLI"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO16927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="80" mass="8853" checksum="E52D9E02ABB4A4FD" modified="2023-09-13" version="1">MTSQLLPLELIDRCVGSPIWVIMKGDKEFSGTLLGFDDFVNMVLEDVTEHDYTGVQTKLPKILLNGNNVCMLIPGGMPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH17</accession>
    <name>A0A9Q8LH17_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761642.1">
        <property type="nucleotide sequence ID" value="XM_047905283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH17"/>
    <dbReference type="GeneID" id="71986013"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06135"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="79" mass="8594" checksum="99D0633AFF3F353E" modified="2023-09-13" version="1">MLTAAQNSSYGADNFYQSDNVTLWPISFPSQYDTTAAAANLFLPDFVNYNTSHPAIIVSPTMGAVKEQSANLYAQKLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH49</accession>
    <name>A0A9Q8LH49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761728.1">
        <property type="nucleotide sequence ID" value="XM_047905600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH49"/>
    <dbReference type="GeneID" id="71986330"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06452"/>
    <dbReference type="OrthoDB" id="3650791at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21452" checksum="B15B44CC18650E73" modified="2023-09-13" version="1">MPSAPRLASKAAKVHIEYPKLAGPSYIALLKHTASFARNREAMAKMARPVFDAEYQRQLQKEFGHDEKICRMGSQAASRMWKSTEARYNRVQPGASGSAVLSEGVEHLKLPPVGSHHKANSGKGQKKESRSLQTYEAFGSKAEKLNADVSFTKQLMDDTFQRAVLIATRYGRSSNKSGVNTAEINKVLTRLCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH51</accession>
    <name>A0A9Q8LH51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extracellular exo-inulinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760904.1">
        <property type="nucleotide sequence ID" value="XM_047904088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH51"/>
    <dbReference type="GeneID" id="71984818"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04940"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18622">
        <property type="entry name" value="GH32_Inu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.115.10.20:FF:000002">
        <property type="entry name" value="Invertase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF2">
        <property type="entry name" value="INVERTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="109"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="6">
        <location>
            <begin position="516"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="640" mass="70211" checksum="51DE9AA8AD432BDD" modified="2023-09-13" version="1">MVVCLQDTDAPWTERGRSNDLVRRPRALARRTSRERRPRSRKVRAEVVISLLSISKMQLKNILPAGALLAGHVAAEVTANPTSTYYRPGVPVGTPAPGNYTSYLRPRVHYSPPINFMNDPNGMHRGADGTWHLYYQYNPVTPVAGNQHWGHATSRDLYTWENQKIPFFPPNNYTQRVMPSDTQQNVFSGSAVVDTNNTSGFFPDQDNGVVAIYTLAEYPGGVQGVQYQAIAYSRDDGYTFEAYEGNPVFDLNSTQFRDPYVVWDAAHEQWVMTIAFAAEFTIGVYTSSNLKEWTHASNFTKHGYLGVQYECPNMLQMPMEGQDEPVWVLILSLNPGGPRGGSVTQYFAGDFNGTHFTPYDSGTRLTDFGKDNYAAQFFNGIPRNESQVALGWASNWQYTQIVPTGLLENGQYRSALTLPRSHHLANISARGYDLISEVHNISAILDQELAYESNLGNGTVLADFANVESGAIYFEANLTGLTVSTLRGVANFTISSSISGEYIRGGINAAGGPGIWVDHSNIRGFDNPYFNDKFSEEGLFTPAMVPESGLAASNSSFNLGVVVDRSILEVYLNGGQVAGTFSFFPTAALDTVAIRFGNVPESATSAASVWALRDTWAEQANANGTVVGNVTETLGSMKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHG3</accession>
    <name>A0A9Q8LHG3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762072.1">
        <property type="nucleotide sequence ID" value="XM_047904624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHG3"/>
    <dbReference type="GeneID" id="71985354"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05476"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="390" mass="43440" checksum="A5D05EBF7606D83F" modified="2023-09-13" version="1">MRLLHVAALLESGRLELEEFIGSDVPSYAILSHTWGHDEVLYSDIASGRAHTEHVWIDTCCINKSSSAELQEAINSMYRAETCYVYLKDVNTPTHVDFDIFRCQFRSSRWFSRGWTLQESLVPRSVQFFVSSGKPLWPFSTTSAHDDRRSLVAEITSATNFAEDIIAAGPGVIHERSIATRMSWAATRITTREEDIAYSLLGIFNVNMPLLYGEGRKAFRRLQQTLLDQSDDSSIFCWTSSAREERAGRIQLSGLLADEPSHFSSIAPTIMAARPQNCAQAQPYSMTNKGLQITLPLIQFSRNIYLGLLDCRLVGRGGATHRAAIYIIRLLSGTNQFARLLPDMVVPASAAIDTSSLKVETILVRQGSGPRVHSLTQEDLPSFFTGNARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHP0</accession>
    <name>A0A9Q8LHP0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06612</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761949.1">
        <property type="nucleotide sequence ID" value="XM_047905760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHP0"/>
    <dbReference type="GeneID" id="71986490"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06612"/>
    <dbReference type="OMA" id="EMWEKWV"/>
    <dbReference type="OrthoDB" id="3609at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000609">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF40">
        <property type="entry name" value="REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14497)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="10"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="193"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="324" mass="35841" checksum="A18B5D6F7A9C0B92" modified="2023-09-13" version="1">MVNEDKKTNILLFGLGAIGSFYAFILSRNQNVSLSVIARSNYDAVKQNGLEIKSAIHGEHTVKIDHVLRSPSEASTKFDYIVLAHKSINPGSIPPLFREVGDDRTTFVIIQNGVGNEDPFHTLYPNNAIVSCVTWTGAVQNSPGVIEHNSNEDMQIGLCPTPTSSSDPRQARLDRFAELLRNGGTKFNFEADVQIKRWEKVVWNAAWNPLTTLTGAPVQDFLNATPEALVMTKQLMQEVISVAQRCGVPLKEGLAEELIDKVMAMQTPIFSSMYQDAKEGRPLEVDVILGTPMRRAKELGMEDKVPVLRAIYAMTMAVNGRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHS4</accession>
    <name>A0A9Q8LHS4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762018.1">
        <property type="nucleotide sequence ID" value="XM_047904819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHS4"/>
    <dbReference type="GeneID" id="71985549"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05671"/>
    <dbReference type="OMA" id="NACNIRD"/>
    <dbReference type="OrthoDB" id="3621521at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18638" checksum="B59C131A8B3F3FCD" modified="2023-09-13" version="1">MALHPNNDAEQSSQTSINSDPIGRYLTTIIHSSINAINTRNLDPKRQPWTLYAPSFRNEPDGNSPIIGNLPTSFSGQRTMTLDTLLDFWKAMVAACPSFRIRIVEIEVCNVEAQEGTAEVALKAESLGIPDGVVRPSVSVLEFRRMSGRWLCTRMRTMPGVDFGGVGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHS8</accession>
    <name>A0A9Q8LHS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial inner membrane protease subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762009.1">
        <property type="nucleotide sequence ID" value="XM_047904604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHS8"/>
    <dbReference type="GeneID" id="71985334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05456"/>
    <dbReference type="OMA" id="VTAKIEW"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="9">
        <location>
            <begin position="87"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="9">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="25959" checksum="3070E4F6AB5D5915" modified="2023-09-13" version="1">MLRWTSRWGSVAARQARLLRFVGRRRESTKTTTNETKPPKTEPTWTQRARQSFPPRLSHPPYSPPLRYCIYVVAIALSGHTFINYVHYCGATYGISMLPTISSFGDWVCISKWHRRGRGIAVGDLVSFKHPVNLGEYAVKRVVGMQGDFVLMNTPNKSEAMIQIPEGHCWVVGDNMEHSRDSRMFGPLPLALISGKVTAKIEWQGWIPHYSRFEPGLEAASIIDDDDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI56</accession>
    <name>A0A9Q8LI56_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762280.1">
        <property type="nucleotide sequence ID" value="XM_047905114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI56"/>
    <dbReference type="GeneID" id="71985844"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05966"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="69" mass="7424" checksum="0CA0BBB336857EC5" modified="2023-09-13" version="1">MATTSSAAADTQSETSDAAAGVDDSDEEAQASEDEEDEGEDFIDDDDEFDDESNPERSENKLSAMHHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIM6</accession>
    <name>A0A9Q8LIM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">(R,R)-butanediol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762467.1">
        <property type="nucleotide sequence ID" value="XM_047905643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIM6"/>
    <dbReference type="GeneID" id="71986373"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06495"/>
    <dbReference type="OMA" id="PVVFECV"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000721">
        <property type="term" value="F:(R,R)-butanediol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034079">
        <property type="term" value="P:butanediol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08233">
        <property type="entry name" value="butanediol_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF23">
        <property type="entry name" value="(R,R)-BUTANEDIOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="12"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="364" mass="38486" checksum="953B1C90D2585E5E" modified="2023-09-13" version="1">MAPTMKAARYYGKEDIQIKDDIPIPECGEGQVMIEPAFVGICGTDLHEYLGGPNFSPQSPHPVTKESIPITIGHEFSGTVKKIGAGVTGLKEGQKVAVQPTIYCGHCGACKVNAENACPNGGFVGLSGGGGGMSEAVVLPSEAIFPLPSNVDLDIGALVEPLAVAWHAVDASPIAQLKDAKCLVIGGGPIGLAVVQVLLGRGAHTVICAEVAKKRQDFAKEFGAHHVLDPSKQDVQSTCLELCGGLNGPDIVFDCAGVPKSLQTACESVRSRGTVVNVAIWEKEVPFNPNWLVFREASYKAVLGYQKKDFQGVVDALGAGKLKPHSMITSKIKMDRLVDDGYLALINEKDKHVKILVDVQGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIQ5</accession>
    <name>A0A9Q8LIQ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762598.1">
        <property type="nucleotide sequence ID" value="XM_047905141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIQ5"/>
    <dbReference type="GeneID" id="71985871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05993"/>
    <dbReference type="OrthoDB" id="4898680at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="583" mass="64370" checksum="FB7F02B15057696D" modified="2023-09-13" version="1">MALNAPKPTRSAEFEPCRYNKQSCDHERPVCSRCIRRGLQNECVYRERPFKKRKLVQTQTPAPAGSTGSASAVPRDEANGILVSDTPRYPNPGFQGTSNHVAIFQQLPCHVDQEQTPIPTVTTSTGGAARSLAHCYCNRNQGEQIMEDCLVKLDLYRVSAPISFWLATDTNLGALSGHFVPGCVKTVEDNLLVPHQDVVAFASALASKTTANSKRPLTFDGTSTFQLMKSEHCGEHILAGGRAAADIRFFPPLYKDDTERDELQKLLSRLAERCLESAVSLGRVNNFLLISQYENFILYTVLFGDQSFDAWRRLGDVISSLLFLGHNEDNKRGPACPLFLAEVRRNCFAQIYLADKELLLFLGRPPRLSRVFCCFQVPRILQVLFLLHKGNLQQPEPAASIHHSKALIVAKEMLSLVVECISFRKGLVDSGCSLNWTIVQYGLPAAGFVALPLIRNNHDHLGAKFIQDLCVFVSEVQAGGVITVTEPNYALLSRATTSLQSLLTQVLAPPPVNHTETVRPPGHSAYQDVSGAGIDLLSDLPFLDEQPPLDFWTNEEEFWGVLGAQAMAFQWDGAEMYGAGMGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIQ9</accession>
    <name>A0A9Q8LIQ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762512.1">
        <property type="nucleotide sequence ID" value="XM_047905430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIQ9"/>
    <dbReference type="GeneID" id="71986160"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06282"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="399"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="893"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1058" mass="112853" checksum="99E1F664AF3EC427" modified="2023-09-13" version="1">MRDKLESTKPDCLTTTLWRTRQRAVSSRLETFAVRPASTDQGTSRPHFTEAPKQTSELHLHLLQIAQPCSSPLRLQASSVCTPPLIMAEETSTGAATPTSASFDAGAQDLVPSHGPQSAGTHGQVKRKLQLSGSFNTISGASSSGRMRPPMPLYSSDTWSPTSAAPLRSAGIPPKSSWDSFDRRSSVAPPLPSPSHSFTTGDPGNMSLPARAAGAINGNVNFTRNGNGRVAGAQVSPGPASFQHTRTLEYHNSPTATSFSGFSNNVAQTDPLPQRQFTYTGHKTGDSSSGGSFSSRNFGMLDTPRSSTSTFASQIGHEQQSSDDQQSVASGSVALSDHYTMTNPDQAGSKCDVWAEKAFARSLRRGLKDPHADWEEAYPGALAVLSALNPEHYQMPYGTRAVNIKSEYPKNVLTSIRVGKYSVMRKVADRIMQVWEAREDPAEKVIFLFSINGSKRFAGLAEMCGPYNPEDSIADWIDASDATAPSVGSFPVTWVYVKDIPYHQFSHIRQPHNDHPVGNMWNGMNFPSDIGRMVIEKFVTTPATSSILGYPRNYKENEALLASGGLDGANDRRQAQRRGTFSSRGERGGGRGGRGGLRINSQNWRSHHDPNQRYDSSEEDHTPLAARPPRMPKVQVDGHAPNLSTAGGGNAVTYQPGMLMTVAVNDRGRLVLVPAPQSSASSTASSVGSRSNHGSRSSNAMAMPGVSSHAGGLHGARSLNSLHQHASSMSAVRPPSAANASLLHPAVSMGNIGSQYGMNNQISSFDSGYGTTLQPGDETPTHRPPPHAARGALSVEPKLMTMENVEDVDLLLAKFHTIVAEQYALQHQLKLPTQSDMAIRLLNAKSARAMAEKNEVGSKLGLLGVKQIASYLPVRRDSVIVANQQQLAITSGNGDISPGRVQGTSMITPSGGNDNTPQAKENTVFDKAPGGSGRAKSHTYNQSWDLQMKKSITDLIKSPKKSPVPASSGQPKSPFFPQTNDSADGRVSASFPTPSRSGPGSTPTDAMKNFSFGPGRTPTDTSKSFSFGPPAEQSFNQSGGSGKQNFSFYGSGGGANLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2M4</accession>
    <name>A0A9Q8P2M4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755434.1">
        <property type="nucleotide sequence ID" value="XM_047900345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2M4"/>
    <dbReference type="GeneID" id="71981075"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01197"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="29485" checksum="56D4093B41ED0313" modified="2023-09-13" version="1">MKRFGIASRETGHGSTASSPFDSDRPRSVAATHDLNNATGLSRISNAFVPRSTLRRSDTSPVQRQNSFATRLASFRRRYGPNGIRSDSPSISQPTDVRLVQGGSPVNYITSKGSSPQTAATSPNYFVPGRSSSLGFTRFDDLPPSPLASHPVTAEDFHSVTSRNADEKHFRCTIHVYDGNSYRDTELKLKGMVAEAGGKMLDTTHRWPGGFFYSMEGALGDNPLEDGTECPGGGRIGVIPFDLSEPVSFKGTRSGMMRAKVVEIPPRAESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2R1</accession>
    <name>A0A9Q8P2R1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755571.1">
        <property type="nucleotide sequence ID" value="XM_047901383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2R1"/>
    <dbReference type="GeneID" id="71982113"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02235"/>
    <dbReference type="OrthoDB" id="5391053at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="59977" checksum="721BC791AF29D98E" modified="2023-09-13" version="1">MRCKNLLSRLPTPKIKWYSFPARKVNVSQEEQTPKPKMADLTTTFAVYMALLKMRLKDAARRRREEDYLVEVGTEVPQFQYQGTQTEAGVQAEGHTSGSASEAAVLEANEDSPPGANGDIQDDGETSTEESSYAYVELDEITGEDFTAGPARFIPASDGLKECIGLAVTADLLSKILDAAEAQRSFARESSLAVRKQGALMNLQADVDMEISGHELRIMQAKEEPGEDDTPTASLEKELENLRLFREHVDDRRRSAEELLRSQANNLIELHSMVGAILEEACEAAKVLEPMEEDPIAEVEALDLQTEYRDFVRQRQNPSWEEGDEDNETVAELQATRDEDLAPEPQELTEEEQAYQDGKDHYFEARERLEHANERFDRREMDRELERGETEESDSDFDLRWVQRNRELTTEVIEAEVAYAEAKVAAFRVGVELRLDDQSSGFGDEDDNGYRESYEAACKASVDQSKITSWLQTTSDDIGLEDDVGSPVEADDWEAAEVAIGDSGSCIMQGSRRRRIDQWKEQQQVCRTEVAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3M6</accession>
    <name>A0A9Q8P3M6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase prx6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756218.1">
        <property type="nucleotide sequence ID" value="XM_047900587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3M6"/>
    <dbReference type="GeneID" id="71981317"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01439"/>
    <dbReference type="OMA" id="VNIRINC"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="31532" checksum="AD919B591B00F0A8" modified="2023-09-13" version="1">MAPPVALITGASSGIGLALTKHLLARDWNVVTADLHAPPETLGEDTLFIQTDISSWSSNVNLFHRAYNWHSRLDFVALNAGIDDRDDIFNSISSTQSPKQPNMATFRTNLLGTYYGIKLAAHYLSLFSPLSSGKSKPGGRIVITASAAGIYPLPNVPQYTATKHALIGLARAMAPAAREVNITINAVCPALVKTNLAPPGMLESFAEEEFTPMSTIIRCFSELADLEKVNDERWVEGGKNGEVVEGNMEDMMYHYAPARPESSSYVDEEGQKAWARAYLERNKAFAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4G8</accession>
    <name>A0A9Q8P4G8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757324.1">
        <property type="nucleotide sequence ID" value="XM_047900511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4G8"/>
    <dbReference type="GeneID" id="71981241"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01363"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF29">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="504" mass="56675" checksum="CF3F3F2ACC4C46DC" modified="2023-09-13" version="1">MAQHIDPSSRSHEGSSSSYGTMEAKGPTVSDDEVKQDPTSKQPGVAIDAAYASEDEGDTTTNPFRDLKVAEYYVDLYEKASYECRHVFDPALEWEKKEERKLVRKLDWHVCTWACIMFFALQVDRGNLAQAVSDNMLDELGLTTNEYNYGNTIFRVSFLLAELPSQLISKKLGPDRWIPMQMCLWSIVAASQAALSGKASFYACRALIGVLEGGFIPDLVLWLSYFYTSSELPIRLSFFWTGLDLTQIITSLLAFGLLRMDVIQGLSGWRWLFLVEGVITLAVGVATFFCMPSSAVATKTWFRPKGWFTDREVGIIVNRVLRDDPTKGDMHNRMAITPARLWRALSDYDLWPIYAVGLIVFMPVGPPSTYLTLTLRSLGFSTFDTILLVIPSTAISCLTLIGLTWLSERFHERSFFAMIQNIWAMPCLLALRFWPGTMTDAWGTYGLITTLLAYPYCHAIAVAWASRNSGSVRTRSVSAACYNMFHLRSCTNMHLKFADSSNQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5I9</accession>
    <name>A0A9Q8P5I9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758345.1">
        <property type="nucleotide sequence ID" value="XM_047902618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5I9"/>
    <dbReference type="GeneID" id="71983348"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03470"/>
    <dbReference type="OMA" id="PLCVHWS"/>
    <dbReference type="OrthoDB" id="10005898at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF25">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11C (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="304" mass="33135" checksum="AD65CEDD22542A1D" modified="2023-09-13" version="1">MSEPASQPGAPTDGAQNQPSHASEKSLAREAEKRMPKKAVSLLATPDRIILRLNKLLAAPGGLSAFLSTFNYTLYLLAHLDSKAGPLKARIAVFLNRQTALPSVTPVVVGEPSPIQNLGSLLSATRTTLRLFGLFPMYAWARQLLQGPKPGQDQVLYATSVAQCTLYIIFQFYENVALLTDSKILPGALTAKYTEKYGGKATAIYTTAYRAWFLGFCCDFVRLAREAQLDSGKRSSKSAKENEENDSRWYAELLVPMCWFPVGFQFAQWNESGFPGFNLGFMGAAGAMAGLSKTKALWDATADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5K0</accession>
    <name>A0A9Q8P5K0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAS-associated factor 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758375.1">
        <property type="nucleotide sequence ID" value="XM_047902188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5K0"/>
    <dbReference type="GeneID" id="71982918"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03040"/>
    <dbReference type="OMA" id="VYAFVEC"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="408"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="514" mass="58201" checksum="3DC4846704C4F267" modified="2023-09-13" version="1">MAGSPTDLTALTEEQQLALQQFTSVTDQELDAALPLLQRCQWNAQIAITRFFDGDAETVDPAAEAARAPPPQDTRRAETLMDSIPNRSSTSRSRASGLEPAPRVVPTPENQLTQQLPFPFSLILLPFNLTYVLFQRLLGTVGYFFPVIPRLLARFWSGRASRPSRDASRRPLGPRDTAARFIREFEEENGGTHGTLPFHEGGYAQAFDLAKRHLKYLLVVLLSPEHDDNTLFVRETLLSPEFKTFANDDNNNIVLWAGTVQDAEAYQVSTALNVTRFPYAALIVHTPSVSSTAMSKVATSSGPIAAQDLITKLRTAMQAQSAELDRVRRQRSEQAQTRNLRQEQESAYERSLAQDREKARRRKEEEAQKEKAEREERERSEQKENKARNLAQWRRRRAQSIHAEPGADVKDAVRISLRMPSGERVIRKFRPDAELEELYAFVECYDQLEEVSEKEVAAPTGYQHTYKFQLVSPMPREVYDLEKGGSIRDRIGRSGNLIVEKILGEDDEGDEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5R2</accession>
    <name>A0A9Q8P5R2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758378.1">
        <property type="nucleotide sequence ID" value="XM_047902192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5R2"/>
    <dbReference type="GeneID" id="71982922"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03044"/>
    <dbReference type="OMA" id="THRMRAR"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="503" mass="56884" checksum="89C7000AE30C0990" modified="2023-09-13" version="1">MQHPDQQVAPVADMTVKHQCSPEADEYDESRFTMEMANDESDPFNPIERAVPSEDTSDTVAMLTGITHRMRARPDRPCRSNRLRPAIYHQLFSEAEDMLFDVLAAVFDALLLVKKMGFEDDDVDRIWTPLTNYTDYRSFLPDSKTDALVGPMGTGKSKLLSCLLGTEDVALSDDGDRGTHVVSEFCGPEVAQQMRFRVKGVYRSDEETMSLMRSLVNDVMDYLEVKDQAGLPDGGEAAAEAVELKMVSDKAVQILTTMLCDVKGFFEEETTMSWFEDQHRSKTSREEIMEFIIPHIERLKNARGFADDQIEVHNADDVFELGEIFKQLSTPTGADDGPHPWPLISKVEVHCKEDLLETGIIIADTPGLEDKNRYVAQNNERYLKEKADKILVVAQYLRLENKVEPMLERCLQAGKISRTELVVTKMDQKDLLKRHEIEELEESVKRNFARRFTVTEHPSIAASPAAKILVDAAKQAVTGLEKINSMLEECEKWEKESEGQPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5V2</accession>
    <name>A0A9Q8P5V2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758871.1">
        <property type="nucleotide sequence ID" value="XM_047902977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5V2"/>
    <dbReference type="GeneID" id="71983707"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03829"/>
    <dbReference type="OMA" id="LWVTVKP"/>
    <dbReference type="OrthoDB" id="47488at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04486">
        <property type="entry name" value="YhcR_OBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834">
        <property type="entry name" value="ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040228858" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="66975" checksum="C6A86E40F0CDABF7" modified="2023-09-13" version="1">MVFSLSLGALAALVGAATAQVVNPTIAQINGNKFLSPLNGQNVTGVRGLVTAKGPNGFFLRSQSPDRDASTSESIYVFGRTVLDNVTVGNVITLNGRVTEYRPTTAAGSNYLFLTEIDRPSNITTISTGNPVVPIVIGQRGLNPPTEQYSVLDNGDVFAVPNNQSRVSVRNPTLDPRLYGLDFWESLTGELVTVRRPRAVARPNSFGDTWVVGDWSTTGDNSRGGLTLRDRDANPEAILIGSPLDGTSNPNVTTKLGDSLEEITGVVFQDFGFYRILPTTAIKVTRSKSPALPPATRLRSNGRCSGITVGQYNIENYYSGSPADQISSIGDHIANFLRSPDLIMVQEVQDDNGPTNDAIVDANVSLSTLRDSITAAGSAVNYSFVDIDPVDDQDGGQPGGNIRTAYLYNPNVIQLRKPNPGSPTDANEVLPGPSLKFNPGRIDPANAAWGSSRKPLAAQWETKDGQHTFFTINVHWTSKGGSTSLHGDPRPPVNQGVDTREQQANITGSFVKQILNLDRNAAVVLGGDYNEFQYVQPLKTLAAVSGLRSFDDVAGIRDVEQYTYLFDMNSQELDHFYVSPRLNRARADYEHIHVNTWVTTDEQASDHDPSVARFNFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6E5</accession>
    <name>A0A9Q8P6E5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759290.1">
        <property type="nucleotide sequence ID" value="XM_047907341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6E5"/>
    <dbReference type="GeneID" id="71988071"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08193"/>
    <dbReference type="OrthoDB" id="10593861at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="23407" checksum="EA9951330373EFF9" modified="2023-09-13" version="1">MSPSITYNTITDDCSLTTYPPTTVGNIVFSTADVRCLCGSSMVGLYTYPAEDYVAAVKCATTKSTTSGLIFDTGATPPPKPPHLRLAVVATNTMAPPSTTQFSTDGCSLSTYPAGTIEGIVFPTADVKCQCGEHGAVMAGVSTWTSDGTAFTACATAAPTTSQPLTTSISASSATVQLSTATTTMGEGHAIVTQGAGGAEGGGPFDAQTAGAKGKMGFAGALAAGLALAATFAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6L7</accession>
    <name>A0A9Q8P6L7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrrolopyrazine biosynthesis cluster protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759500.1">
        <property type="nucleotide sequence ID" value="XM_047907727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6L7"/>
    <dbReference type="GeneID" id="71988457"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08579"/>
    <dbReference type="OrthoDB" id="3634487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48312">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48312:SF1">
        <property type="entry name" value="SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="38591" checksum="B614DAD64F8272E8" modified="2023-09-13" version="1">MGSIGDSRLAHRQTPRSDNIRDVFFFAHTRTASHVLCRLLSKQPGWNQSNYHFFHTFEWARKTFGFGPASGISPQHQKELERRLQEAFDEIQRARSSAAEENRCILLKEHTFYIWEPARLLQSMWGGPSKQPSFTVIEKESGDVLDIVKTNPTIFPDSFLRSWRPIFLIRHPAVSFESWYRAESGAQHVDITDKSWAFYTTFRYQRELYDWFLTNQTDAQSVPLIIDADDMLEDPTTINRLCELLNMDPTHVPSTWNAVEPEENASKRTMRFMGGYWESTTIDKSKSSRGLDIAKRYVLWQNEFGTEVADELLRLVEKATADYTYLKSRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7H0</accession>
    <name>A0A9Q8P7H0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760460.1">
        <property type="nucleotide sequence ID" value="XM_047903320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7H0"/>
    <dbReference type="GeneID" id="71984050"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04172"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058645">
        <property type="entry name" value="NTF2-like_dom_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26534">
        <property type="entry name" value="NTF2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040193909" description="NTF2-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2-like" evidence="2">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="22880" checksum="9EC306D6BA385604" modified="2023-09-13" version="1">MKTTFIASLFAFAALALATPAPQEVSISTISKEDSAALKKGPKDDSSWSGLDDSQARSVCNSWRNIYGKGSKYKDTCNSILTNDFEAYSCSTQTTWGKRPTSNCQLCNSRDVFTNDILSSLPKLAEAKILSYYYTKKTVILYANIRFQKSRDFVAVIFMITTEWSKKKGVQISKIEYEYDTLDYVTNYDSKKKCSALPFKGNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P958</accession>
    <name>A0A9Q8P958_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PI-PLC X domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762068.1">
        <property type="nucleotide sequence ID" value="XM_047904626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P958"/>
    <dbReference type="GeneID" id="71985356"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05478"/>
    <dbReference type="OMA" id="YPYLMPE"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF80">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040354212" evidence="1">
        <location>
            <begin position="22"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="357" mass="37891" checksum="EC7728FFCCE3C779" modified="2023-09-13" version="1">MFRTYLSSFLVLAAGLQSVLAQSSSTACNNSPELCSRQYNNVTYLGARNSPFLRDDTTDFSTSGNQFYNTTRQLASGVRLLTGQVQYPNGTIDPHVCHTSCELLDAGTLSSWLSEIKTWMDSNPNDVVTILLVNGAGATASELASAYTRSGLSDYAYMPASSAATTTWPTLQELISNGTRAMNFVATLADNTGATYLMNEFDYIFENDYDNSEVSDFSCDVNRPSNLANDTSTAISSGYMPLMNHFLYENQLFGIQSPNESYANVTNGASGAGNLASAAATCASTYGKAPNFLLVDFTNMGPAIDTVDSLNGVSNPTGRTTLPTAALSETSAAAILLPGSSSLWMSLGAALLVVLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9B5</accession>
    <name>A0A9Q8P9B5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase sdnJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762142.1">
        <property type="nucleotide sequence ID" value="XM_047905307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9B5"/>
    <dbReference type="GeneID" id="71986037"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06159"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="374"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="502" mass="54802" checksum="065F0B415590B2B1" modified="2023-09-13" version="1">MAAFKPRRILLLTNVDRGEANVFLATAAALVETDSSVELHFATFPGLEEPVAAVSQNARRHAPDAREIVYHSISGLTMADGLKKYLAENNVPRKDDYLPLSFLAPLRFSTTLKAIGDTIPIMVPYGSVDMAEIVSCIIDIINSVKADLVVVDTLMTAALTACYHLGVKFACLSPNAIKEFAAPVQPWAAGLWRYPALFSGYSFPVPLHLIPFNIFLTLYTAHTFIGDSHRHAVAQHLASNLKVTLRTPIDLLRNRPDNVKILVSTLPELDFPSIIPDHVLPCGPIVQTASPIAESDPELEQWLAAGPVIYINLGSICLLAEDQALRLAKALRCVLDRQDTPPRVLWKLKPYGDYKVTTTGSKIHDVLGPEIDADQVRIVTWVQADPFSILQTGHILCSVHHGGANSYNEAVLAGVPQVVLPQWTDCYDYAQRVELLGIGRIGNKTCKPKWETEELSQVLLDVAFGKESGSIKKTATHLASICHEHGSGAAHAAKILLAECDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9W3</accession>
    <name>A0A9Q8P9W3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762935.1">
        <property type="nucleotide sequence ID" value="XM_047906654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9W3"/>
    <dbReference type="GeneID" id="71987384"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07506"/>
    <dbReference type="OMA" id="NDVWNSH"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="58" mass="6744" checksum="50DD2D6C16F16D00" modified="2023-09-13" version="1">MTHETVYYSRPRTYGKGSRGCRVTGDKKKSGVIRKYGLNMSRQAFREKAEDIGFQKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAE4</accession>
    <name>A0A9Q8PAE4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763177.1">
        <property type="nucleotide sequence ID" value="XM_047906524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAE4"/>
    <dbReference type="GeneID" id="71987254"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07376"/>
    <dbReference type="OrthoDB" id="10574518at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="29631" checksum="5E5A13D3C3447A2F" modified="2023-09-13" version="1">MQRTRACEADGEESSAPLCIKTCSVFFSLHSLSASASLYSRSTSEMHSPMKLATVVVLALSGLATAFPQYGETTTTTPKGYGETTTTKKTTSKTSDTCSYSPTTISSTIKTTKYETKTIATSTPKVGSTCKNEDQTKTITKTLTVSTSKPTTVTSTFTTTKVVTKPVDTTTKIPTTSTSWVKTVITTSYSTLVPGYTTSTIKGETKVTETITSTSKYPVQAPVYETSTKTELSTIKGSTCYPTTKYEGTTKYSTVTKPTNYVTKIVSSTKVCGPKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBE6</accession>
    <name>A0A9Q8PBE6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal peptidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_07592</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPCS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763737.1">
        <property type="nucleotide sequence ID" value="XM_047906740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBE6"/>
    <dbReference type="GeneID" id="71987470"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07592"/>
    <dbReference type="OMA" id="WVGALTW"/>
    <dbReference type="OrthoDB" id="10261524at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
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        <location>
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            <end position="32"/>
        </location>
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        <location>
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        </location>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00045670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR016089"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="27830" checksum="BAFC7AD2EA3D7C47" modified="2023-09-13" version="1">MHSSLVRVQNVFGFFTSVAFAVAAAIAVSVLLSPQTPSASLELKNVKVAKGRPHYYSPKREEYAHVTFDLTTDLTSLFNWNTKQIFLWVEASYPSTSPSTIPPSEAVVWDAIIPSSYAPFHQNTYIHPTPSSKKLTAKEKKALKNKKRIPYPAGGSAGIVRLEGQKPKYQITDVTGKIAERENATLTLHWNVQPWVGMLTWTNRKSYGRWEGLKGGKSEVFTFPALKGSETVKKEDMKTETGGEKNRGSPA</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO19590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="118" mass="13793" checksum="F8F432D88EF00FCE" modified="2023-09-13" version="1">MMSKLDQQIWNTGTIIYRSKIFMSCMAAAAKGRIEDKPRADLLYQVKDAFQLWDLRFIPEFNPIFGQRHTQMLRHIHKIALDEGLSKKRRVENHLTDEELLLFWMKIATSDGLAGIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCG6</accession>
    <name>A0A9Q8PCG6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methylsterol monooxygenase</fullName>
        </submittedName>
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    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09841</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="161"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="37416" checksum="D6C2DF8B25C0FB25" modified="2023-09-13" version="1">MSLTLGMDYFNNVMNTTTASSIADAMLPHTNNTYWHEFDQISQYNVTLGFFERLWAAWYAYMGNDVLATGIMSFVMHETVYFGRALPWIIIDRIPAFNKYKIQNQKVPSPKEQWDCAMLVLLSHFTVELPQIWFFHPFAQYCGLGTSVPFPPWWKMAYQIAIFFVLEDAWHYWTHRAMHWGPLYKNIHKIHHQYSAPFGLAAEYASPIEVMILGLGTVGSPILWCAITKDLHILTMYWWIAFRVFQAIDAHSGYEFPWSLHHFLPFWAGAAHHDTHHEKFIGNYSSSFRWWDYVLDTESGPEAAKRRRERKMAKAKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCH8</accession>
    <name>A0A9Q8PCH8_PASFU</name>
    <protein>
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        </submittedName>
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    <organism evidence="3 4">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71990085"/>
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        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18582" checksum="CC63179E23C8F4FD" modified="2023-09-13" version="1">MYDGAIDPNADPETNLRRVRAIEAAGGSARADGQVDGSAGSARVDDLPTSDQLIDELLEQLTLANQSNGAPNTNGNAGASDKSSNFVWWAIGFLTLVGLLCLVLGAAIILQLVFPYWWAHVFQMQSYWMTDREGYKYGYGWTIIGDEQCQMRGRYFYCEERTIDRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCU6</accession>
    <name>A0A9Q8PCU6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="1" type="ORF">CLAFUR5_10494</name>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCU6"/>
    <dbReference type="OrthoDB" id="3695143at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="49884" checksum="8ACE4BBC7E15BD21" modified="2023-09-13" version="1">MATLLPALESQNTATSGFVDDTNILAWSSSTKENCRLLEEKHKICEDWARRHGARFAPEKYNLIHFTRRPRFHNMQASIQIQGHTTNPANQLRILGLWVDPALRWRKHVQAILRKAEQNMASCQRLTASTWGADFRQSRLLYTAIVRPVFTYGSQVWSLGERACPSKGLVAPLAKIQNQCLRKVTGAYKSTPTRMLEHETAIPPIDLYIQGLRTSYLGKSAQYPVQKVIASAVARARESVPAHKGIRPGNEPNYRARDEQLATQWEGEKSFVEQLWKERWNNQVVGHSGRPQPAGQPKEWSATKSAVKHPPKLIHYRLTRAQSSIATQLRSEHIGLQGYLSWRKVLGYTNTSCPYGYRSQNVRHALLVCPRWSLGRGEWMAKARNRTIRALLNNAEDLRRITNWILEKGWLEQYRLVGAVQEERTRRSATRPARSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDB2</accession>
    <name>A0A9Q8PDB2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764706.1">
        <property type="nucleotide sequence ID" value="XM_047908979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDB2"/>
    <dbReference type="GeneID" id="71989709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09831"/>
    <dbReference type="OMA" id="QIEYMAM"/>
    <dbReference type="OrthoDB" id="3650757at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15795" checksum="BFFBD6E9F7E5D7A1" modified="2023-09-13" version="1">MAPPTDFLENSMGSRLLSLPAELRNIIYELTFTTDYDDDEKIRHSRTSRHIDLITTKPPSKMLLCTCRQIYDEAHLIHRTQYRKFWSSGKFLLDLGPARSDNGYTVRLRPDVDHVNSLQIEYMAMGFIMFDKRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDW0</accession>
    <name>A0A9Q8PDW0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-dependent 3-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10996</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765010.1">
        <property type="nucleotide sequence ID" value="XM_047910144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDW0"/>
    <dbReference type="GeneID" id="71990874"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10996"/>
    <dbReference type="OrthoDB" id="6251714at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="33591" checksum="AF4259395E5E0A59" modified="2023-09-13" version="1">MSFLKSGHLFRTFNASIAQLRRPTTTTTLLQHSIQALRMTSSMGKRLEGKTIVVTGASSGIGKSTALEFARTSPNNLKIILTARRIDALKQLAEDITKEVGSGVKVLPVQLDVSKADQVRSFIQNLPQEFQQIDVLVNNAGLVKGVDKAGDIKEEDISVMMDTNVNGLINMTNTVLNQYKTRNNGEGAGDIINIGSIAGRQGYPGGSIYCATKAAVRTFTEAIRAELISTRIRIIEIDPGQVETEFSVVRFYGDKAKADKVYEGVTPLTPGDIAETVVWSAGRPENVVIADMLVFPNHQASATQMHRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE66</accession>
    <name>A0A9Q8PE66_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765186.1">
        <property type="nucleotide sequence ID" value="XM_047910374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE66"/>
    <dbReference type="GeneID" id="71991104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11226"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="28068" checksum="557C9DB083C70E15" modified="2023-09-13" version="1">MDSAAGAEQPPVGQAAATTQDDDSAPAAISAEPPVEQAAATTQSRQKPRRRRRSCPPMLTTHLNNGDLASAAIYAQPPVEVVAATKQTGDLKNRPVPVIMKWHEFGGPNKEEELNSFAGKALFTERYVVMLTSTTTHTEFVTDVMETLRVGDLGRSTPGRVCRQFFIIDPTELRKARNGTKLDKITNRFRKPEPFEPVTRIVSNGKNWEASRELLLQHDDYSLYCRAWPLPDDWSWHQYVYNSNCRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE77</accession>
    <name>A0A9Q8PE77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765172.1">
        <property type="nucleotide sequence ID" value="XM_047910349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE77"/>
    <dbReference type="GeneID" id="71991079"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11201"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="11410" checksum="514A2D8D06DF2017" modified="2023-09-13" version="1">MDSHEEVASPTLLVAPAAEISATPFTPEFCRRHSPLSSHPPVNDVPSPVDSNASGDSDVPSIPDSNDEDFSTEHVSMSKKVQGRLNRFAARAKSFVKGVNHKVDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE94</accession>
    <name>A0A9Q8PE94_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11247</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765220.1">
        <property type="nucleotide sequence ID" value="XM_047910395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE94"/>
    <dbReference type="GeneID" id="71991125"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11247"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06423">
        <property type="entry name" value="CESA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF2">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="214"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="53960" checksum="E6ABA48C45E55437" modified="2023-09-13" version="1">MLSFSRGVLPTSRHPAHNNGMASSQSSESGKRSTLSLASSIASSIRSGALAFSDWILDWTPFGTIKVFYIFYMATNFYIAATCVIESFLGLTPVRDARKAAMAVEATGKFPSDLNGTADNLPIIDLVIVAYLPNEQEIIRNQVLYACEELLYPREKLRINLVYNTPKAIEPLESELVLLPEQYKNLRVIKVPGSKSKADNLNYFFGLQSDAEIIGIFDSDHCPHPHNPRWAAERFLADQAVEIVQGRCIVYNTNERFYARMIAVEFDKIYAISHPGRSRMFGFGLFCGSNGYWKAPLLRAHKMLGDMLTEDIDSALRAYGLGKKAVHDMNVTSFEMAPNTFKAFWNPPNGKRAVDKRCGILSLLTIREISYYLVTQHACLLLSFVIVDWPHSPAELGRLLFFRYPMAQWFFFATIVALLHTLYFTEKVRSEFTSFKDMVNFCIIYIPYLVLMATMGLYGHARQIIKYSSWNPTVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFB7</accession>
    <name>A0A9Q8PFB7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765760.1">
        <property type="nucleotide sequence ID" value="XM_047910047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFB7"/>
    <dbReference type="GeneID" id="71990777"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10899"/>
    <dbReference type="OrthoDB" id="3650741at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18564" checksum="EEBA44CDD61F7EB2" modified="2023-09-13" version="1">MAPISTSDLRRHLESLLQEPYDEIYNLTFAAESKTHTVTESWKPPHLLQVDRASRLTFAASFFQDATFVFRSASFPCEARNIASSWLKSQSPKNLERVKEIRPVFKRRPHKGHSHDSADRAEIERQMLKLILALMQTAKDGQGIHFDHPAHRLAKNACAMVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY5</accession>
    <name>A0A9Q8PFY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-coumarate-CoA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766129.1">
        <property type="nucleotide sequence ID" value="XM_047908255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFY5"/>
    <dbReference type="GeneID" id="71988985"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09107"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="454"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="568" mass="62950" checksum="1F613BA82FAFC2B0" modified="2023-09-13" version="1">MPKFPSLQQDILLPRDITTWQWLFESPTCSPLRRYPEKELGGFTDVVAKETLNWKQVKENATYLSAALVKKYGLKETETVALFSANTVWYPVAMHATLRVGGRVSGASLAYNEEEMTYALQKADAKFLMTHPHSMDVAINSAKAVGLPQENIFLLEGELKGFKNIKTLIEEGKQLGEQVPVCSIPKGKTNFDICGFLSFSSGTTGLPKAVMIAHQNVIAQCLQIMPITPSDHKRILALLPSFHITGLVHVLHLPLLINASVYCLPQSTMKLMLDAIVEYKIPELLLVPPLIIRLVRDPLVEQYDLSFVRRFSSGAAPMSDEIIQLLQKKFPNTGFKQGYGMTESCSCIATHPPWLYDFSYAKTVGTVCASTTVKIIKEDGNEAEIGEPGEICAKGPQIVMGYLNNPEATKETFDEEGYLHTGDQGSIDSHGIITILDRIKELIKVRGIGVAPAELEDLLLGHEEVEDVAVMAIQDDYSGEVPKAYIVPKPGQEPGQALGRELLAFVKSKKVRYKAVKEVEFIKEIPKSGSGKILRRMLRDQHRKGAQGVVVREESMGWWGRGVGWLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG55</accession>
    <name>A0A9Q8PG55_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766180.1">
        <property type="nucleotide sequence ID" value="XM_047908168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG55"/>
    <dbReference type="GeneID" id="71988898"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09020"/>
    <dbReference type="OrthoDB" id="10546970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="21479" checksum="FFCEC60D04D959B6" modified="2023-09-13" version="1">MQAQATKFAKPLSLLHTKPAGPSFKDQAEDFDVITMSPSHTPPAARSRRHSRASSRASSTVVPTPSGEAANPPPIPTAIPSGSRPISAPILPISSKSAPDPSPSSSNGRCTTPLPGNSIPITKIRPQPGPPLDAVSVAEGTNPAVYMPTKGDGFHHDPHRERIEKGGSDKGKGKGKAGVFPRQSQQNFHFAMIASNIENAFGAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG72</accession>
    <name>A0A9Q8PG72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766196.1">
        <property type="nucleotide sequence ID" value="XM_047908015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG72"/>
    <dbReference type="GeneID" id="71988745"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08867"/>
    <dbReference type="OMA" id="HENEITI"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="20881" checksum="52F5A652A1D68C82" modified="2023-09-13" version="1">MAAPSTPPENKTCHLLELPAELRNTIYRYTLCAEEEIAITSDSNNCHQPALLRTCRQVRQEAAPIYYHENEITIDAPDFDPSLIIAFWQHAGRHIPFDKRSKVLIDIGRNVRSWNNLLSWVKAFWDGRVTYMVPGDPGDYEWNAGAGAFAIAIKVKAMKGAWADVEDWLEIYKMATNIMIGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGR1</accession>
    <name>A0A9Q8PGR1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">CLAFUR5_08971</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="26" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Sterol glycosyltransferase responsible for the glycosylation of ergosterol to form ergosterol-glucoside.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766566.1">
        <property type="nucleotide sequence ID" value="XM_047908119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988849"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08971"/>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000303">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000391">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="19" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="15" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="18" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="25">
        <location>
            <begin position="301"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="29"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="90"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="214"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="481"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="1429"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00059773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="UJO22200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1462" mass="163012" checksum="55E856EB17A08D69" modified="2023-09-13" version="1">MASQSSILLDRRRSSGGFKTRFGSIKLAKVRSRERSAGPSTAAMDLPDRFKSDDDEDVDDGTGVAGQDGAMFAQQSMYGVLAATQSKAKLRFQQESGSESEGEDEEVKRKRSEDTARPSPSGSGRTTPKQHERKKSSDGKKEKGEEKRHRRKLSENKLVRSFLKPIRERADSNVPDPMSQSQFLPPRKEEAVEDARPISVRSDAPILDRKLQAMAKADMDSSRTSLEGRRSREGKSEDASKDRSPKTLPQVIANIFQFKEPEEVVSEYPCWYLQNVLLQGYMYITQKHVCFYSYLQKRTNAVAKTGHLGKQGKHSYRYRRYWFVLKGDIFSYYKSSADPYSPLGVVDLRYAITADVTGGVGKDYTEFTITTQDRVYLYKADTAESAREWVKQLQKVIFRSHNDGDAVKISLPIENVVDVEEASMVDFAETIKITVIADDETFATDEYFFTFFSLGKEALNMLTILTEGNDAKKALAEDNAMSPLSRVRSPPTFDQSPNARSSPRPIQEPVRSTLSPLSGRGSPRISSEGQRPSIDMTRPSLDGNRRTSFDRGRRSVSAESRGIYGVRSASKSPLSPRIDESMESFVTSSEQPTDSSVDEETMQANMTASTMLADDGVFRGPTLRMPQPRRTVSGWTVERLRRESQHSSRESSTERVRVQPPSRQQTDHRPEFKRTESGGSGRTLEAEKLQPADAAAPGRLVRGISTPLQHAITVAGMVRSSSKRMGSYLSSSPKTTLSNWSDAIAGGKRHYKDTEGLAPDDSIQDPEQEVDVAEHERRFQAHFGLPISEKLVSTFYAWLHKTIPVYGKIYMGTRRFCFRSLLYGMKTKIMIPYKDIINVQKQRGFRWGYPGMVLVIKGYEELFFDFPSVELRDDAAVTVLRNLETVQDAALSMILTEEEQQEAEDAAAENELLQAARKDGSADHDLQLTSSLSDPDAPPILFDDPSASILEFKPKESMKITCLSIGSRGDVQPYIALCKGLLAEGHKPRIATHKEFKPWVERHGIEFAEVGGDPAELMRMCVDKGLFTPSFVYEANSTFRPWLDDLLKSAWEACKGSELLIESPSAMCGIHIAEALEIPYFRAFTMPWTRTRAYPHAFATPGSKMGGGYNYMSYTFFDNMFWALISGQINRWRGKMLGIGPTSMDRLQQNKVPFMYNFSPSVVAPPLDFSDWIKVTGYWFLDEGDDWQPPEDLANFINKAREDGQKLVYIGFGSVTVSDSRLLEQQIIDAVLKADVRCILSKGWSDRFETEAQKALPPIEVPPCIHQIRSAPHDWLFKQVDAVVHHGGAGTTGASLRAGVPTIIKPFFGDQFFFATRVEDLGVGMNLKKVTANQLGKALWIATHDARMRGKAASIGEQIRGEDGVRTAIDTIYRNMDYARSLVKIGGRQGSVASQSAGEDLSEENWTFVEKEVEAGSIAAFVQAEAAMAGMQPQPQPQSGKAGGSGHGRQMSLGSMVMRGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGW8</accession>
    <name>A0A9Q8PGW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766567.1">
        <property type="nucleotide sequence ID" value="XM_047908678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGW8"/>
    <dbReference type="GeneID" id="71989408"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09530"/>
    <dbReference type="OMA" id="VEYTTRG"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF17">
        <property type="entry name" value="NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="7">
        <location>
            <begin position="34"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29668" checksum="23C52B1D0EE2350A" modified="2023-09-13" version="1">MVRETVRDPNQGLLSTRAGEEKDERPIEMRIEASRGELFSMAYDKLVIGVGAYSRTYGIPGVKENAFFLKDVQDARKIRNKLLSCFETAALPTTPVALKKQLLNFAIVGGEPTGIEFSGELQDIVREDMTKLYPGLIEHVRITVYDVADKILPMFDETLAKYAAEHCIKEGVNVKTSHRIRGLKRGFPKVNGSGNLHDDVKASGFTLSLQNGEESEVGCGLAVWSTGLMSNPFVDKALSPSFTAPASCVRMLNDINPSPEVRTEHGRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHH7</accession>
    <name>A0A9Q8PHH7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl-CpG-binding domain protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766871.1">
        <property type="nucleotide sequence ID" value="XM_047911618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHH7"/>
    <dbReference type="GeneID" id="71992348"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12470"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="4">
        <location>
            <begin position="898"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="406"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="753"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1088"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1154"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="753"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="772"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="800"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1183"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1205"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1218" mass="133360" checksum="C6DBCDA85181D155" modified="2023-09-13" version="1">MSTNTTNNKRKAPPTSSNNPTRDEHEHEYANKRLKLTNHAHPGRTPVLHRTGDGVAKSLDFIDFATVVVDSITAGHAPDILTAKGARKRWRDEMKARAVEVQRGRDGTGRGEEVKQVKDSRITLGEKRPALDVGMIARTRLARPPVKEWHVTDAPPQCAIKPDPGIKEESEEVKQVMDGIPTVEEKRPALDVKVLARTRLARPPVKEWHVTDEQPRRATKPDPGIKEEPEEVAPTVDQVCVDTREHKKAPEATIATARRSEQRRPSPPRRVLPTYRPPGLKKFTDLPLPNRGPPQLDDSDDSSESESDSSDDEDETASKAPVQGSVSESFADRIFTTEKEDSDRRSGDTLDLVESSNSREENGQTEIPGKQQSERPLGSSYGSISNHASEFGEIVCISDAGKARNANIEQPATSSSQPKSSVPMDAALPTPLATPTGTSHDHSKSASQQTDNATKKTMRTGKAGSKRSGRGRSSARSDTLAEISPDCLRTRQELFATDGDSDDVYDDIEDVTEDLLSESLLSMDQCKPPNSRDSACEVDLDMLMTANDSVGKVPSERDAVVMMVHDDGRSFDAWALDDTDVMQAMYEGRADGGALQDAEGAVADQVMDDAAVKLDLSRTSSSLSSTLSELGRAPTPPTVDVQDTEIAPAISPEASANSEAAMPVSCDSSKVLVPLRRKMTGISSKHFSPAKITKTTNLDRLNRQTPMKGREAVVAADTESPLTALQNALDRQVFPSEDVAADEQAESANNLLENSESVNASVPVNNPAAGTSKRKKSSRRRQRKVDDVGVSTIVDEDQEYNQSGTQADNVKTPVRQTRSTVKTPASKRKSTGKISEHFITDRVDLYNTTAGGGRIPAGTSRAPVPPIDATMFGLIQEKIWREPFWLIIAVTFLNKTAGRSAVPVFWKLKEKYPTCEALAEADQADLLEMVRHLGLQNQRSKRLIQIAKAWTADPPVAGKRYRTLNYPTHGDGKASTIANLVEEDAEDCAGLLEIGNIPGCGQYAYDSWRIFCRDHLRGVADDYNGTNAKIHGFVPEWQRVLPDDKELRACLRWMWLREGWIWDPLSGEKRRASEEEMEKAILGEMEIEDPQERKFAAQAAGVESSAKKVKRGGADRSLEETPAKTRSRPSANDDQIGAEVLEDVCLENDASAIDVAPPTIASSEAASKARRPDAQASIEESKAKHRKRGRQRKSIPVHASESAKPRRSARHQVKKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHP8</accession>
    <name>A0A9Q8PHP8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
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</entry>
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        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14 22" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="41"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="240"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="500"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="599"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="706"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="783"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1157"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO23068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1257" mass="141555" checksum="F115ABD0F61B1DCC" modified="2023-09-13" version="1">MAYNGDAMMAQMDGGEDDIDVNMITAEDCWTVIHSFFDAKGLVSQQLDSFDEFASTTMQEIVTETPPIIIDQNIAAEDEESNQPIIKRRVELHLEDVAISQAAMTEGDGSTRALFPHEARLRNLTYASPMFLSITKRQKLCRERSVGGWLDDTGYWNDPPDHDGQTELHWDDDPDNPPETQKEIFIGKLPIMLKSKICTLRNRSEQELYAFQECPFDQGGYFIINGSEKVLIAQERSAANIVQVFKKKGTNTPVVAEIRSAIEKGTRLISSMQLKLYKQSANSNAHGETIKVSVPYIKSDIPIAIVFRALGVVSDEDILNHICNKSDTKMLEMLKPCLEEAFVIQDRDSALDHIGRRGQQQGTKDRRIRYAKDIMQKEFLPHISQEEGSETKKAFFLGYMVNRLLQCHLGRTDEDDRDHFGKKRLDLAGPLMAQVFRLKFQQLVKDMKAYLHRCVETGREFNITLAVKTNILTSGLRYCLATGNWGDQKKAASAKAGVSQVLNRYTYASTLSHLRRTNTPIGRDGKIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMCYVTVGTPAEPLVDFMRQRGMDLLEEYDPVLNPKATKVFLNGTWIGVHKNANDLTNMMRSLRRKGVLSFEVTIIRDVREREIKIFTDAGRVCRPLFVVENDPKNPNNGSLVLQREHCQRLADDQNVLAELAGVSEEEREQKVFGWKGLVDAGVVEYLDAEEEETAMIIMTPEDLEEHKLMRQGVPMEDTRADPHRRIKSKPNPYVRTWTHCEIHPAMILGICASIIPFPDHNQSPRNTYQSAMGKQAMGVTLTNYNTRMDTMANVLYYPQKPLATTRSMEYLKFRELPAGQNAIVAIACYSGYNQEDSVIMNQSSIDRGLFRSLFFRSYTDQEKRVGMSVVEAFEKPIRSDTMRMKQGTYDKLDEDGIITPGSRVSGEDILIGKTAPMPPDAEELGQRTSLHIKRDVSTPLRSTENGVIDQVLLTTNTEGLRFVKVRTRVTKVPQIGDKFASRHGQKGTVGITYRQEDMPFTADGLTPDIIINPHAIPSRMTIAHLIECLLSKVGALNGQEGDATPFTDVTVTSVSDILASHGFQQRGFEVMYNGHTGKKLNAQVFLGPTYYQRLRHMVDDKIHARARGPLQILTRQPVEGRARDGGLRFGEMERDCMIAHGASAFLKERLLDVSDAFRVHICEICGLMTPVASLKKQQFECRPCKNKTKIAQIIIPYAAKLLFQELAAMNVATRMFTTRSGISIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKZ4</accession>
    <name>A0A9Q8PKZ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768807.1">
        <property type="nucleotide sequence ID" value="XM_047912724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKZ4"/>
    <dbReference type="GeneID" id="71993454"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13576"/>
    <dbReference type="OrthoDB" id="5304367at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="15705" checksum="233F125F9AE63680" modified="2023-09-13" version="1">MGARLSQPRGPGGTTESSLATSPSAQKRGPRFNSRMIAAPAAAFTMACILFVYARTSIRAAKANAQRHRDADTGGEGVSLLNEHRRRHGQAPKLEEGTMKELGRQLVRGEKRDPKTEAVERSISEEEERLKALKGRRGGRGAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM13</accession>
    <name>A0A9Q8PM13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769314.1">
        <property type="nucleotide sequence ID" value="XM_047913622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM13"/>
    <dbReference type="GeneID" id="71994352"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14474"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="725" mass="78427" checksum="1A375C1A952794D1" modified="2023-09-13" version="1">MSDLGGGSAARASNNGGARTGGPVPVSGGAQIRTPQMIMRDREAREQRRMEESRQAEEEQKRRQAEERRTSAERRAAAIPGAVPRFSNTSSQYSPDVSAPQVPRFDSSSGDQRRSSRIAGDVAGANMLGDPTSRASQDLPSRPAAQDYASGRARGPALSQQDQPRPAPATTGATRRTQPQQATRTQATTAGAQPSSSAHASTAATAPGEGSQRGTASSFPHAFERWETLSSHWEGLTSYWLHKLEQNTEDIRETVPNASTLNRQITDLSAAGANLFHAVVELQRLRASSERKFQRWFFETRADNERNREIQAGMERQLKVERQAREDAARNTTDNSIAVENAKREVSEMRRELMISKDEARRAWEELGRRNQESLDTAQSLKEGRVTLVAGVQVVPYFGGPASRTGSASQGPQRPVTRDGPSGYASTGLASQAAAAGMQSPGDEREYYRHDAASPTNTDPFTDSGRQQPPSQSLAQGSYHPQSYQQGHGQDRTPTSAATMQTAIPASSSPCQQVTPSQYPAASSPAQQRIPQPSVSTSEAQRYYQQGSQPAHTAPGASVPRTTAILPREEVRFVGEGSYGGSNPEIGTEYALDGRGEVQYDERGNPIIFRQRGQPQPARSSASEEDFDTEEAVRRERDQAAQFHGGLIPEAPSVPSNSAAAMATYTPATAGGGGGGSSGGAESTPDYEGEGYDDYQQYVPRHHHPTRLSDVLEEEEERSSRRTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMI1</accession>
    <name>A0A9Q8PMI1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769519.1">
        <property type="nucleotide sequence ID" value="XM_047913686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMI1"/>
    <dbReference type="GeneID" id="71994416"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14538"/>
    <dbReference type="OrthoDB" id="3489571at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040213052" evidence="1">
        <location>
            <begin position="21"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="96" mass="11168" checksum="AB5B7D2B8D8A66E2" modified="2023-09-13" version="1">MDDILAIWLWFGFILYLISATLKASYQEEAHGDNISGYWYSDENTIMEDATACMCQYYKNRNTGGNQWDTNGWHLGRDKMHYYCTEKCGAEWSAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMU7</accession>
    <name>A0A9Q8PMU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_14207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMU7"/>
    <dbReference type="GeneID" id="71994085"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14207"/>
    <dbReference type="OMA" id="WYRQYET"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
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        <location>
            <begin position="65"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO25337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="499" mass="56042" checksum="65DF61B550A55135" modified="2023-09-13" version="1">MNRFKSSPPEAQVVSSEKDIGHTNHLEQVSSNEERKDGDLEQGAGQRDWTPEEERKIVWKVDFRVFPMLCIVFGLSLLDRSNISAAFIAGMSTDLELTGTRYNIALLVFFIGYGLFELPSNYIIRRLGARWWLSFLITTWGVCVLGMGFIDNWKLLSVLRALLGVFEAGLFPGAVFIIGSWYRQYETARRISIFYMAALLASGFGPIFAYALSLISVGNGKYQQGWRWIFIIEGIATIVAGLVSPFFLIEFPEKVRFLTDRQKYIALERLRLEKENREIVHPNMKQTLVMLCDFKLLLYSINYFIAASSVYSLAFFAPVILRQGLQFSYTKAQLLSSPPYIFTIFASIAAAYVSDKIRLRWPILNFQALIAIIGLLVVLYAKPPGVRYFGLFLATYGTQGNVPATISYGQNQTARLEKKGIVAAAMISAGAIGGICGSSIFRSQDAPQYLAGMWATIGMQFLYIVNTSCLSWYFKRQNARADKGEVAVLEGVEGFRYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP2</accession>
    <name>A0A9Q8UQP2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763289.1">
        <property type="nucleotide sequence ID" value="XM_047906629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP2"/>
    <dbReference type="GeneID" id="71987359"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07481"/>
    <dbReference type="OMA" id="EANTMFR"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040423721" description="Rhodopsin domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="126"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="434" mass="49303" checksum="CDD4CB3DD8006C8C" modified="2023-09-13" version="1">MRVFWLCIPAGLLCQGRQVLPSPIQRASVQQVTSNTAQGLAACTQTCLEQYPGPLVCTHKALFDSDITKCVQTTCPLLTDLLTWENRYAEECGLEARDDGARELVIAYVFFGISTLSAAARLLSRSRWLEGPGFWWDDWIMLAMWFITIEMAVCPFFSRTYWSGRDVIGFVTVHDIERVLMWTYVSEPFYLIGTFGTKLVWVFLYLRMWEANTMFRKLCWVTVGLLAVVMVGYPIGAIVTLWPHRYYIGESAIVRQNFWGIDLIPAVIAIGVQIVLFDFWTLLLPIPKLIRLTGVSKQRRTAICAVILLGFVVTGCSIVRLTVILPLQDSRNPNWDFGHFGTWSEIELHLSMISCNLPAIAGLVHRMMLRRRRMTSIGFEDELEDSDGRSKSRTLTTKTGQSIDIEEGSTFEAELVEDESGKIVMRKKKREQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQZ1</accession>
    <name>A0A9Q8UQZ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Importin beta-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763531.1">
        <property type="nucleotide sequence ID" value="XM_047906414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQZ1"/>
    <dbReference type="GeneID" id="71987144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07266"/>
    <dbReference type="OrthoDB" id="2016913at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1021" mass="113256" checksum="467B95591A11E1A7" modified="2023-09-13" version="1">MTTYGIPVSAPTNVQEVEQLVKRLYQPGTPRVIAQIDDQLKLLQHSPDGWQLADALLGSDDSNVRFFGALTFQVKLNGDGSVVDPDLSQWARLDAAAAQTVLSKLLHWTAQLDRAGEGHLVRKKLCAALGTYFLQSPIPWQRPLLHLAASFYHGSAVDEDRLSTAHDAIDQYLPTLNDSQLVNLLWLSGTLATEASRVDNSTPENTHVHHLMETLAVDATKVMLYALRQPAPAVTGRTKAESVKAESLSCFLNWVNYAQPMWTSQQQALDHLRGLVPQLAPLLTDQMLQTEAMDVFRDILESYTTFFQPQHMALLANVIHQYAGPAMLRLLHDREPEVLPVAQLIIAFGIANVQQVVEDPQNELGSKVVVQLLLAILESPGFPGDDDEVSIHSIEFWNTYIEYVNEEMYSRQTAQEKPAWLDHDKAVCMRLSELLWSKMRTPPAEVAQDWSDDESEAFKEFRMDASDLMLSVYVRLGNEMLQRFISIATTALSAKNWQDLEAALFAINTLADNVLEEPAAEELLGQIFSSALFREIADFSQPIPTQTRRTAIDMLGAYGQYIERHAEALPDTLRFLFASLETPGLFISASKSIESLCSTCRNSLTGELDGFLAQYDKFAQSETSEPYTNEKVIGAIASIIQAISPESAKAQPLSALLDIVDSMVVNTRQLLAQPDVEKAAAIGVSSIDCLVKIGKGLQVPEDVPIDLYEDEETPKGQANYWRDPEGQAIQFRILNICQTMLQLLPGVGEVVDSVCQVFKAGFAETEPGPFVFPPNMIVSFLEQCTISTPHLETVLSTVCTLIVQYSRKDQPRIDDEISRIYARAVTFVQSLNGDPSQDPSIAQACIDVFNRMIGRYSNIFLDVAGSGVAVQLILDFALKALDGPDLMPKRSAADFWRRVMALKQDQPDETILDRAEQVITAYGLPLCQALMNQICGRSQRSELDSLAEPLKGLIQNRPQTRTWLETAITSDALPAIIPSVGDAEKRRFVQQVISLRGDTKRTRDVVKNFWAACRGTVASYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URH9</accession>
    <name>A0A9Q8URH9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3500 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764102.1">
        <property type="nucleotide sequence ID" value="XM_047909052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URH9"/>
    <dbReference type="GeneID" id="71989782"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09904"/>
    <dbReference type="OrthoDB" id="4539697at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489:SF1">
        <property type="entry name" value="DUF3500 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="49278" checksum="08B02B25AFC2AC2A" modified="2023-09-13" version="1">MPATANGTTNGHVDEDLATAFRKHLPDLTSPRFTTSKEQTPYEYSEAFQKTHHPPWLYNLTETWKELLKEPYKGVTNDGTVRPNLYKNEDLGVNTAQITAAVNTTLSLLTPSQATQLRYPLASKEWRCWSNPEFLLRPFGLRLEGLSDDLAQSILSILSATFPPEGYAKALAAMRINHFLGDLCSVPQLMNQYSYNFLLFGSPSSTEAWGWSLYGHHLCLSVFLKGGDIIISPTFTGAEPNLIDAGPWKGTAILHKEGELGLKLMQSLSQGEQKTAQIFKLMRDPGMLQSGDLKVDRWNQDDQRHLCGAFRDNRVVPYEGVKVSTMTSEQQDLVLEIAEEFLLYHPHKARQRRKEQIKEHFEETYFSWIGGYGDDDAFYYRVQSPVIIFEFDHHSGVFLTNTEPAKYHTHTIVRMPNQGDYGQAWRKPEERVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USA0</accession>
    <name>A0A9Q8USA0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764926.1">
        <property type="nucleotide sequence ID" value="XM_047909986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USA0"/>
    <dbReference type="GeneID" id="71990716"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10838"/>
    <dbReference type="OrthoDB" id="3637343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="15"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="24864" checksum="30EAE1677474F312" modified="2023-09-13" version="1">MTEEDTATSRALGVNELLEMVLSHLDVATLMDARRVCKTWHAMAESSVALQRRLFLQVAPTYDGRDLFECCNYNLIYTTPDCCSIKPGPIYTDGYFNCFWEEAIHTEYYEYDVTFFLRNTKNHALHRPWGAQVEEPIWYRMLLFQYPFKLGKVKVKVELYDRDVEELEVPIEGDKAGVRFRDVCERVLAVARQWGLERAMGREYIHGRERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE1</accession>
    <name>A0A9Q8USE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclochlorotine biosynthesis protein O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765046.1">
        <property type="nucleotide sequence ID" value="XM_047910811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USE1"/>
    <dbReference type="GeneID" id="71991541"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11663"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="42110" checksum="8EBE36E9FE6DD99D" modified="2023-09-13" version="1">MAASLLRYCAKANWCKDQDFMALQASSKSSVDDCSDGPWREHEEQKRLLSPEILETPPTCRRHHHLLFGLVMGNIFLTIVTILLAVALSIAASQDPSLTVYSPAKEAVRYYVHRFRPALGNETEYMGFPTDETDQRWEALYQYNASVISETQARRLLTPTMAIPGTKRYLVELEVFHNLHCLNELRKLLWPERYRLLEQLTSENGTIDRSSFGFKHWGEIISAGRPSMRLTRKDHCVDSLRQALMCNADISPISWHVNVPFNRGIYPRLATTHTCKDFSQIQKWAAEHHAPSFEQRIYDFEELQRVIDDTDIDHSTEEDLQNQYWLFPGDKWFKHWREHTYHGEVSRPQIYPTSRHEWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE6</accession>
    <name>A0A9Q8USE6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765061.1">
        <property type="nucleotide sequence ID" value="XM_047910274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USE6"/>
    <dbReference type="GeneID" id="71991004"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11126"/>
    <dbReference type="OrthoDB" id="10587766at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="38801" checksum="05F1C464F4311CFD" modified="2023-09-13" version="1">MEYTQRLAFRQLPHERPIPDLIQAESNSRRSRVLFLYERPRTSPRAWLEKLPLELLLMKLEHTSTVDIANMMEISTALRFMIVPQLTYLGDRIASFHLERIRAVASTLDLTGLDIFAAVQHYASWRGESNHGSNFYPLRSQWREGFRRGYMHVLSGSNPEWTPDKHETMLMDELLTCLQTIYHLRHRSLASRNQSNGGSRRLKRLARSCVLRGPADCPSAWRDHAFETMENLYLFGEEDILKVLDQAEKVNILDVVCGQGVKRMPRGDWEARSKDSHGGECLRTFGDSLPMLHGDLRYFSRSGVDGQLRNIISSGPQAEQNPLLRAAILEDLDICILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTR6</accession>
    <name>A0A9Q8UTR6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oligopeptide transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09758</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766428.1">
        <property type="nucleotide sequence ID" value="XM_047908906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTR6"/>
    <dbReference type="GeneID" id="71989636"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09758"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="733" mass="81132" checksum="66BC732892A3ED7A" modified="2023-09-13" version="1">MQIVSLGSDKSLASQDMMRTIVAAIQPSGHESKKDLQITTVPLDSGVLSEKERSFRHVVTAKQAEFNLNLTEEDFLTTQEEAEKLTLDEVTQILKHGYSLHEFDPNFPIKILAEIEAFLENNEAILVAPEKYAELVQEMELQAAVLTTSSPYSEVRAVVDNNDDVNTPWSTIRAWTIGLFFVCAVGFMNQLFSVRQPSITVGSDVVQLLCYPVGKAFEKFLPDIGITLFGVRHSLNTGPFSKKEHMLITIMATVGSTLPSSRYIIFTQFLKKYFNQSYSGSFGYQVLMALSTDLMGHGLAGLCRKILVYPAYYVYPKSLVTIALNSSLHKDKNTPVTGPAKKLWTVSRFKFFTWSFVCTFVYFWFPNYIFTALSAFNWITWIAPENVNLSAVTGFAKGVGLNPLPTFDWNIQRMTAYPEVSEWWYLGLNVVAIALGVAVVAGWQTYTTVGVIFFGILLSLVYAIPAGVIAATTGIVVELNVIAEFLGGSIQPGNALAMNFFKCDGYVTTAHALEFIKDLKLAHHVKIPPRHTFWAQVVATVVSCFVCTGIMNFQLRNIKDICESTQSARFTCPGVNVYFSAAVQFGSMGARKVFGTGGQYTILLIAAFPIGLAVADHWAREIHPVAFLSGGLVSTPPYNLSYMWPAMPFAWYSMIHIRGKYLAFWSKYNYVLSAALSIAIAIAALVMYFAREYSSISLEWWGNNADSGCEATACTRLKLPKGSSFGPSPGHCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUR7</accession>
    <name>A0A9Q8UUR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767433.1">
        <property type="nucleotide sequence ID" value="XM_047911221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUR7"/>
    <dbReference type="GeneID" id="71991951"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12073"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="73" mass="8518" checksum="0E5AB90700047812" modified="2023-09-13" version="1" fragment="single">CLTPAEQRLANHHQHEVSQYREHSSIKRRSGDSQNHPPQWLVQDCPGRQNRPQHLWRQTTLSDLGRSGGQKAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUW5</accession>
    <name>A0A9Q8UUW5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767671.1">
        <property type="nucleotide sequence ID" value="XM_047912176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUW5"/>
    <dbReference type="GeneID" id="71992906"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13028"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="87" mass="9929" checksum="9A0074983BDF47F8" modified="2023-09-13" version="1">MSHTITTTHLTSKEPEQQKFDTEKGRSGEDRVEAQQKFDTEKGRSGEGRVEVKNRTQPKHQKFDAEDAPSGEKRVDIKVEVESDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV28</accession>
    <name>A0A9Q8UV28_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767925.1">
        <property type="nucleotide sequence ID" value="XM_047911880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV28"/>
    <dbReference type="GeneID" id="71992610"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12732"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="17616" checksum="F02D10E6787DEB1A" modified="2023-09-13" version="1">MSDRRSLLDLPPELWSHIGKLSTDAWIEDWWSPFHSLSESLAQPPIAQTCRTLRGKLLPYFFRRNELFTDCWKRGYKWTECGRFLRALERGTRRLIGGWKVQVGSGKYAEEDLETMKDYMDTTWSVEYELELCPVATNDVNLVYRVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVL6</accession>
    <name>A0A9Q8UVL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerol 2-dehydrogenase (NADP(+))</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768464.1">
        <property type="nucleotide sequence ID" value="XM_047912447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVL6"/>
    <dbReference type="GeneID" id="71993177"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13299"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="174"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="49080" checksum="EC30A38732744004" modified="2023-09-13" version="1">MSQTTLPIDTSLGRLDTLPGELRNQIYGYALASDGKIGFDCYQVKDGTLRFCHKRPRNGSSELALATFTSLSLTSRAIATESRPLFYDTNTFEITFVEAKQARDWRGRLEWRTVQYGVSRERIVMVPGWNWKTPFCAPGFAIECLAKTRKLEMRDTRTVTLNDGNKIPLLGFGTASDRKKVKQAVAAAIETGYRHIDTASVYNTEVEVGEAIKESGMPREDVFLTTKLHNTDHARVAEALKESMQRLQTNYVDLYLIHWPCSVDPEDNSKVLPHWDYVKTWQEMQKLSATGKVKSIFGPKHRLWAFTICLIVLPASLILWGVGAAHQIHWFGLIVAMCGTAFCNCCGITPSVNFLVDSYPAVSGDGMTTVVIIRNTMSFDHPLAEWSRHAELLHQCCVRREDSGLCCVPGHDMEGEDVEVEVEGGVLEKKHVSMGMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWA9</accession>
    <name>A0A9Q8UWA9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769171.1">
        <property type="nucleotide sequence ID" value="XM_047913149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWA9"/>
    <dbReference type="GeneID" id="71993879"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14001"/>
    <dbReference type="OrthoDB" id="3353407at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="792" mass="91696" checksum="F9DB0AC559F4BB3C" modified="2023-09-13" version="1">MGSRYRSLSGALIDPEKQRNSNDYDSDDAPSLISSRNTSSSHMPMLGQPPSKPSFAYHLPRRRFSRYFTLVIATILLVFIYYLYHSAFTSRAEVQLGLKKPPPPPPAWESFPFLKRYHGGIRTLVDRSENKPEYPADEDVEVQRLKDEALRLKESMDAETRREKGFQKREEKSWQERAVRFDPYGKEGKEFESPVKCYLDNKTKMEVPQLLSYKGVTEGFPEPVMGGHDLLGLRNDVCFERYGRLGPYGFGYSKKYGGSGAGMEGEKEGSEKVWGDELEIDYTKVRWAEVQEQCQQANAHRFKPKPQKHMNHFYSAMPYGGPAKQKELKEETVKTVSDSGKQLLNRTAVVIRTWWDFQYDDEDMFYLRALMNELSLQSGAEYDVHFLIHVKDDNMQIWSDDETYQRVLDDALPEEFRGMGTLWSERQMGLIYGGVHESMYRDLPVHGAYRSTYMPVQYFAHMHPEYEFFWHWEMDIRYTGHFYHLFQQVSQWAKQQPRKGLWERNGRFYVPSEHGTWEDFRQMVRVQTEHGTASKSSVYNKLAADAGTANPMDEASRQPETPIWGPLRPSGEGDEVDSPLNDPLQPTTYDKDTYSWGVGEEADFITFNPLFDPHTTNWILAEDVTGYNTTDNNYPPRRTAIITASRLSRRLLETMHRETALKRHTMFSEMWPGSCALHHGYKAVYAPHPVYIDRAWPTSYLAAIFNNGRNGASGGSRTSVFSDERQHNFLGTTWYYHAGFAPNLWKRWLGYRVDNDGGEEFEVNGEGRICLPAMLLHPVKQVDLVREHKEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWF5</accession>
    <name>A0A9Q8UWF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-N-acetyl-D-glucosamine 6-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769337.1">
        <property type="nucleotide sequence ID" value="XM_047913518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWF5"/>
    <dbReference type="GeneID" id="71994248"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14370"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491:SF2">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="4">
        <location>
            <begin position="67"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase dimerisation" evidence="3">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase dimerisation" evidence="3">
        <location>
            <begin position="291"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="469" mass="51463" checksum="28BBAE0855737396" modified="2023-09-13" version="1">MSTTRAVTSSTYSLYPTIPKNSKSFVPIRAPFTPPETPPACDVESQDDYIGNTDINYCTASLARPVVAVVGTGYVGLHLVEAFATAYEVIAFDISQRRLDEIEPTLKAISAEGTSDATQLSRASHILISVSTIIDQNQQIDTSCIKSAIKTIDTFARPGTTIIIESSVAVGMTRDLLQPLMDTKGFLCGMSPERVDPGRSYPRYDEIPKIISGLDTASLSSIQRLYSEVFSTLVPVSAPEVAEMTKLYENCQRMMNIAFANEMADACKQLSQSLTCKINAGSKQLSPSPINIGPWEVSKAASTKPFGYMPYTPSLGVGGHCIPVNPYYLLSNSSFPLLQACTERMRDRPARIADHLMNRIGFSAGSRPEVLVVGMGFKRGQSVLSHSPGLALATHLLNSYDVYVEYVDPLVEEQDVPPVPQLRHEVDWNVEYLSRFDAIVVAVDQPGLDMGVLEQVHTQGQYVEWYVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXL3</accession>
    <name>A0A1P8YXL3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp9-9</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 9-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp9-9</name>
        <name evidence="3" type="ORF">CLAFUR5_05638</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943081">
        <property type="protein sequence ID" value="AQA29252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXL3"/>
    <dbReference type="OrthoDB" id="4954273at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671799" evidence="1">
        <location>
            <begin position="24"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="90" mass="9946" checksum="2F92E9C56C217693" modified="2017-04-12" version="1">MKLVPLSCLLGLASFGLASFGLADYSKFCNYGTAGDGSCEQEGYHTFCCMDDKRGEYVHHMTVRQWPNSLNPEGTTSHCGNNWEGEIWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXT5</accession>
    <name>A0A1P8YXT5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09880</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">0WU</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="KX943159">
        <property type="protein sequence ID" value="AQA29330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764611.1">
        <property type="nucleotide sequence ID" value="XM_047909028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXT5"/>
    <dbReference type="GeneID" id="71989758"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09880"/>
    <dbReference type="OMA" id="ANAKYYW"/>
    <dbReference type="OrthoDB" id="77201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF13">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE EGLC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671807" description="glucan endo-1,3-beta-D-glucosidase" evidence="7">
        <location>
            <begin position="17"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="316"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="357"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQA29330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="472" mass="47514" checksum="AAB6CA69BC317D2C" modified="2017-04-12" version="1">MHFTLSLLALAGAATAQIRGFNYGALYADNRARMLSDWEADFRAAQELPGVGAFTSARLFTMVQGYSQSDIISALPAAVATNTSLLLGLWCSGGDAAFQNEITALRAAVQQYGEQLQGKILGISIGSEDLYRISPTGIENESGPGAGPQQLVNYVSQAREAIQGTAWADVPIGHVDTWTAYVNASNNPLIEALDFLGVDAYPYFETVNENSIENAEGLFFDAYDATVGASMGKPVWVTETGWPVTGPRSGAATSGTENAEKYWKAVACKLLGKTNTFWYQLNDGADQEVSFKVIPADRRAPLYDLSCEGADTTQPTASASGSRSATQAAATATGSSATSGGAAAGTPNDDAQNAAQSGASSGSGSSSSGSGSSSSGSGSSSSGSSFSSSGSGSSSSGSSSGSSSSGQQGTSSGSGSSYQPAAGNNATQGNTTYTGPSYTGSNPSSYTGGASAMVGSAASAMVLAAAAAVAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5R6</accession>
    <name>A0A9Q8L5R6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755709.1">
        <property type="nucleotide sequence ID" value="XM_047899700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5R6"/>
    <dbReference type="GeneID" id="71980430"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00552"/>
    <dbReference type="OrthoDB" id="3642326at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="58468" checksum="F604F6CE45C2D29C" modified="2023-09-13" version="1">MHRYTDLTGRRADWKTYSSRLCEHCHRLEEHSRLQQHSLPLGKQNNRISSNSSLLGSINTTMMEARSRRIPRSVPVPARNPSRKGSTKRPTPTTPTGLTEQQIHIWEHAITLYYGFDWQAAADTFASLARSITSDLEQALCLINTALICARLGDFAPALAILGESQPTKEVLPLTLFLMGHMNFALCELDQAESDFDSALRTLDNRPQSYRRYNVDFVLQEHHIRRSLEVLHTYRRLGSCNDMMDSLPADCIFGMPGSGPDCSPARSVMSTGSDECPDLTDFSDVSAPATPTVGTPTAEQNDVEMLWQIPMDEPEERLQRLLANSSLDDKSSRLEMILDVPDPIRIRLTPPRSPTPIRAASSAVPNVATYQPTGLPPRVPPKSRLRMEPRDARVEDGTTRYLAAYIRDLPAQGNALQPKEAKDEQGSTRHIVDFIRDLDRVEKDQQHTVVDYRTRRSESSDGSSKPGSLGSIDLYTADGDHERLATTYKPVIKKHRYRSGLGSVLSRKPAKQNDPTPSSSDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5U6</accession>
    <name>A0A9Q8L5U6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01666</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755801.1">
        <property type="nucleotide sequence ID" value="XM_047900814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5U6"/>
    <dbReference type="GeneID" id="71981544"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01666"/>
    <dbReference type="OMA" id="FVQCPGH"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="43"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="397" mass="44611" checksum="194EAB3DB9849B9E" modified="2023-09-13" version="1">MPSTEQLVKIFAKLTKAPNVTQGPLLLKVLWTLLAFSIIIVALRIWTKLQRAHRLYYDDVLMVAALLVGIVHAVMVTVAISKGFGRHIIHLSIPQIEGTMKYGALSLMFGWLSPMLGRVAFCCTIFYLTKTDSRVWIWPIWVFIVMQVAVNVVGVVVFYVQCGTELDIFWHVQKQLNYEKFCWDPRIQTDYQYLMGAVNTVTDCFLAVIPAILIENTKLSRKAKTTLWFLLCLSTLAMISSIVKTYEAKMLSEVTDYTYNLCSYVIWVSVEINIVIITASIPFLRPLFKRPRLPVSRPGTRNRLDAAPPSWRSHIQLGSALSTKNSSRIKVHEHSTQSASVSSLDAIFGTTTTEEIEGITVTREVQVSYEKLDAPSVHAALVGLVQGEMANPGLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L638</accession>
    <name>A0A9Q8L638_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755790.1">
        <property type="nucleotide sequence ID" value="XM_047900373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L638"/>
    <dbReference type="GeneID" id="71981103"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01225"/>
    <dbReference type="OrthoDB" id="77835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006576">
        <property type="term" value="P:biogenic amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.70:FF:000013">
        <property type="entry name" value="Glutamine synthetase bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000005">
        <property type="entry name" value="Probable glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF12">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="9">
        <location>
            <begin position="180"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="60866" checksum="D1E1D73DE6091B8F" modified="2023-09-13" version="1">MGAVSDLLLLSGSDHCAEVVSGAHIHLQHPPLQLYSTYNNNNDNDTTHPPTSQARDTMAITDDPSELEFADLQELLKHDISIKVAGVDIDGQLRGKLMSKKKFFSIVKSGFGFCSVIFGWDMHDQTYFKELKVSNAENGYRDITAEIDLSSFRRIPWENNIPFFLVSFREPEGASLSACPRSLLERTVDKIEAKGMGALAGAEYEFFTFRAPTDTHISPTSDNRNSSATATFLQKHPVNHLPSLEEGMFGYSLTRPVHNQEWYYGIFDACSKFRCDIEGWHTESGPGVYEAALEYGEIRQMADRAALFKLTVKSVSSNYGITPCFMAKPREGLPGNSGHMHISLKDNKTGRNLFAREKADPNPPFEGLEDVSDIGRQFLAGVLDGLADIMPLFAPTVNSYKRLVENFWAPVTVSWGLEHRAASIRLIAPPTSPPKGTRLEIRVAGADTNGYLVLAGILALGYRGIEKKMSIPIPPLGKGEDVGGSGDKGQRLAKSLKEATAQFARKESVAREVLGDDFVDHYAGTREHEVRLWDEAVTDWEVRRYIETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L722</accession>
    <name>A0A9Q8L722_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756414.1">
        <property type="nucleotide sequence ID" value="XM_047899348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L722"/>
    <dbReference type="GeneID" id="71980078"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00200"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="81" mass="9089" checksum="AFEF3050159464FE" modified="2023-09-13" version="1">MFAENTWLNVIPRTNGSVLAPPATRHCSPGKDTRDAYMADADLPQTHWIDEENDNFAREDDDSETGFLVLQHRVTRASGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L772</accession>
    <name>A0A9Q8L772_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756478.1">
        <property type="nucleotide sequence ID" value="XM_047899959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L772"/>
    <dbReference type="GeneID" id="71980689"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00811"/>
    <dbReference type="OMA" id="FTHRHAL"/>
    <dbReference type="OrthoDB" id="267048at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12676">
        <property type="entry name" value="RRM3_Nop4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12677">
        <property type="entry name" value="RRM4_Nop4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000406">
        <property type="entry name" value="Related to Nucleolar protein NOP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034809">
        <property type="entry name" value="Nop4_RRM4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034808">
        <property type="entry name" value="Nop4p_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="48"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="148"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="306"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="491"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="645"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="674"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="700"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="738" mass="81965" checksum="DCCF0CE228C345A0" modified="2023-09-13" version="1">MGPARKKQRLSNGSAVTVEQHDDSVEDTPQAATETSAEAQEKAVQQKRSLFVRSLPPTATSETLTDLFSESYPIKHAVAVIDNEKKECKGYGFVTFADAEDAAKAKQEFNGHVLDGRKLRIEIAEPRQREGEGGHEKHGKKQEAPQQTKLIVRNLPWSIKRDRDLEKVFLSFGKVKKAYIPKKGPGLMAGFGFVVMRGRKAAEKAIEGVNGQEIDGRTLAVDWAVEKNAYQGAANESEEQEEEAEEAGGGVTLGGADEEHIDQDVSDAEEDGSEGGGSDEDEPDEEDLDMDEEEEREPRQPDDRSSTIFVRNLPFTCTDEDLEDHFSQFGSTRYARVVMDYGTERSKGTGFVCFYRKEDADACIRNAPARIPAPSADKSSKDGQPALQTRSILQNEDQDPTGQYTLDGRVVQVSRAVDKSEAGRLTEEGVASRYKRDTDKRRLYLLSEGSIPSNSKLWQPLPPSEQAMREASAKQRKALIESNPSLNLSLTRLSVRNLPRSIDSKALKQLAREAVVGFATDVKAGLRQQLSKEEVSRGGEEMREADLARKKKGKGIVKQAKVVFESAGGSKVSEETGAGRSRGYGFIEYYTHRNALQGLRWLNGHAIGYQVKDGQGKLSREDMQDRKKRLIVEFAIENAQVVMRRNDSEKKARERSRAVQDGTVVKDGDTASKPSKRPAKHEKPGSRKRKRAPESAQKAPESDKAKKEPKKPIDEKLARRNQIIGRKRAMRKNRKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7B8</accession>
    <name>A0A9Q8L7B8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_00349</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756549.1">
        <property type="nucleotide sequence ID" value="XM_047899497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7B8"/>
    <dbReference type="GeneID" id="71980227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00349"/>
    <dbReference type="OMA" id="FCHTFVN"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000057">
        <property type="entry name" value="Vacuolar membrane protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053976">
        <property type="entry name" value="PFF1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22251">
        <property type="entry name" value="PFF1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15 21" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="673"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="711"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="738"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="172"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="452"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="19">
        <location>
            <begin position="765"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="604"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22251"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="989" mass="109437" checksum="58AECC2231D61CB4" modified="2023-09-13" version="1">MAKKWSYNPLAFLGPQVTIIGSLVYIALFVLLVTNHETVPNAPSHPVPIAGVNLTEAWLDLKVLSDAYHPWGSRRNEAVREYLLQRIDQILDANNASSKTVHSVDGVFRSRSRGTRDVTVFANDTSNFTALDGFTKKPWTLYGESTNILVYIRGKDDGAGEWWNSTKDYTGPSGVLVNAHYDSVSSGLGATDDGVGIVSILQLISYYTKGKKAPKRGLVALLNNGEENGLYGAHNYVRHPLAQLPHTFLNLEGAGAGGRATLFRSTDAEVTSAYAKSPSPFGTVISGDGFKRGFVRSGTDYSVFTEELGLRGLDVAFFKPRARYHTDQDDARNAGPNSLWHMLSATIATVDELTSHQGRDFEGSPDSTGKLSTGKCSNAVWFDLLGQTFAVLRLNTLFALSVALLVAGPIIFILLEVLIRKSDKWYVFAGRRYLHSSDDDDAVRLHGRRGFFRFLLAFVVATAVTILLAYLVTKINPYIVYSSEYAVWAMSLSAWFAIMWFFLKGAAAVRPTALHRMFVLIWLYVLAWILLVFATIGENNLHLASGYFVVFYNASAFVALLISYMELFALPTTRKYVEHALGAQAESGSTRPGSRSSRQLLDQHDDVNDEAEPSERTSLLQDATSRSNQHTFTSFGRRRADRDEVPEDTDDPFLNKAYLDEQAWSSSLPQWTWILQFLVLAPVNVILIGQIALLLTHAINQTPADGNPVLPIYLLISVFAILLLLPLTPFLHRFSFHVPTFLFLVLVGTMIYNLVAFPFSRDSRMKYYFVQQVDLSSGINNVSLIGLDGYIQNIVQEMPSAAGQSLYCEDSSSSNHTSLPNRNGLTSCSFHGLAPKVVPKGYAGLSANRTRWPTYSDWIDFNLTHSGHTASIRIQGMNTKICNIKFDNAVSGVNIEGSASDPRQKAVPEGGSNEVHLFSRTFDKTFNVNVTWEGESAKGQKGRVSCMWDDANMPGVIPAFDELRRNEPVWSAVTKTADGLVEGFKEFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Z1</accession>
    <name>A0A9Q8L7Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756894.1">
        <property type="nucleotide sequence ID" value="XM_047901171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Z1"/>
    <dbReference type="GeneID" id="71981901"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02023"/>
    <dbReference type="OMA" id="MCYLSEQ"/>
    <dbReference type="OrthoDB" id="4716584at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="735" mass="82357" checksum="CEBC92DA89E09862" modified="2023-09-13" version="1">MHPPSPSSTPDDAASNTQQPKPRRFVPKPIETITKSSKTARKHSPEKQEAGQAPKVRRFAPEPVETTTRSSKSTAAKQDTKPAIRRFAPQPIETSQKTSKDRTPSKSRAHIRFKPDLVETTYGGNRKSSRRSSAQSETTSNIAPEDVTSRKFKPEVISTARRSRRAGDLNDANYQDYRTEEGFVIHAREHQKHAGLKSSDEGQARSETGEGDHAVSPRGHECPPELRRQISPLDGSAPARPSLLKPERQHSFRCPELDTIESSESERNSARSSLSGSPGQGSPITASDSSFNEFYKHATRTRESVDESFSQYLLDLEAKRARQRLQEQALAAFPNSDFHEPVQHYVNDDHDSFDMEIEDRPVTWEGFDEEEYNSRPIRRESTKVNWDQLELQRHAEEREQERRANNATAAKKEPPKENSPWWSPAAGASIHQPDNEMRSMRDRARPPMLGRDLMFPRCPSPEPARFDVTQGCERLRQQMCYLSEQLQNTTTANVGGLWCSPAAKKPEQKVSPATSTTTAKLVIGKGLWGGFCIQEKSETPGLAPPTGPTGLMTPAPRVENLNPFEQSFSGRGDAGAARTHLTALATPPTPPESVHGTATDLGHLDTVLATERDFEQTFEKEFPDSFITQVFNYLSLGYPTLARPFDEELSKIARIPVSELRQDDIKAKQSPRGYIRLGPDFESVGGERLTTENCVRWQALKLYVREWARQEKNMVQEAPPGGNWATTNRRGSWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L810</accession>
    <name>A0A9Q8L810_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756972.1">
        <property type="nucleotide sequence ID" value="XM_047900414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L810"/>
    <dbReference type="GeneID" id="71981144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01266"/>
    <dbReference type="OMA" id="PSTHHMS"/>
    <dbReference type="OrthoDB" id="5364404at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="394" mass="43929" checksum="DD36E099E2AC87EA" modified="2023-09-13" version="1">MFSTKLTRVAHRATCNASISTASSTAAQRTAASACIAARRPHQRRHSSSKASCPPENSPSGAKPAPATKASSGPEEKAPIAEPTSQQRTPKRISRTKRSPRAAAAEKVENRFAGLPSVPSTQHLEKNDVSVSSFFALHRPLSLSTTIPPVASSEAFWSIFESRKEVDPWENGNSAERRPEDVVYALGSLFDNLDGSASEVQDDSVRWEVIQESPSNQDGVKHLDGAPRLKSLDEQVAAFKPFQVPPPPQPFPEDSKASMKKKASKPRQRSYETTFILTEVTSASGERTYTGSFSPITRIPSASDQATIEGSTSASRYPFRERMNERTRAYQLRQQQKMQDKPSTQPFVRRAPSARRAKMLLLSVKRQRKLKMKKHKYKKLMKRTRNLRRRQDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9A6</accession>
    <name>A0A9Q8L9A6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylacetyl-CoA ligase epaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757502.1">
        <property type="nucleotide sequence ID" value="XM_047901876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9A6"/>
    <dbReference type="GeneID" id="71982606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02728"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF265">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="434"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="58093" checksum="7F5CB8624B80F458" modified="2023-09-13" version="1">MNYIRFLHEQRPADPEAIIFIDAENPDRTVTWRQYYSMVQRLAAGLRHLGLKKSECVALMSRNDVCYYIFADAVVLAGGIFIGLPFESKVAELEGHLKAADVKWIFAEPRLLEQAHAAFAAVGLLESHVLAFDAAELYSGVEDSFSALLRTEEPSTKEQFDASIGGEQTCFRFLTSGSTGTPKAAEISHACSIARIQQSSKVIPGGDVRQLQVIAMYHATGVLTHVRAVTGRVVAYITAKPDAATTIDYVEKYGITDMILHPRLAEDLAEVVQSGARDKQALRSFRGARIGGSLCRDSTVKALKAVLRDDAHVTISYGSTEAWTLASLVPRMTYVADHVGGQMPDIEVIVVDPETLEEVGVNKEGEICARGPTVFSGYANNPEATKTTFVTRKDGVWFRTGDKGVFSSVHQQLRITGRYKEIFKVGSEEVAPAEVEAELLKHPALTDTTVTSTDGRRKVGDLEVMAYVVSKDDTLSAQDVVDFVASRVSAWKAPTGGVTFCDGIPRTAHGKIDRKALSNASVQERSARYLSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA56</accession>
    <name>A0A9Q8LA56_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="9">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757890.1">
        <property type="nucleotide sequence ID" value="XM_047902876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA56"/>
    <dbReference type="GeneID" id="71983606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03728"/>
    <dbReference type="OMA" id="HTITCET"/>
    <dbReference type="OrthoDB" id="6425924at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="12797" checksum="52F989C5E1BFBD3E" modified="2023-09-13" version="1">MTSTIGIPIKLLNEATGHQVTVEIDSGQTYRGKLIEAEDNMNVQLENINVTQRDGRVTHLDRVYIRGSHVRLFIVPDMLRNAPMFRSRGTRGRGVGLARGRATVNRARGSGRGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAD1</accession>
    <name>A0A9Q8LAD1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758217.1">
        <property type="nucleotide sequence ID" value="XM_047901813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAD1"/>
    <dbReference type="GeneID" id="71982543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02665"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="39405" checksum="D841A6913A45F005" modified="2023-09-13" version="1">MDLVTKGSEVPHHWITNRSPQPTNNHRLAPLTISNHTNKLTDPREHAINAQRGLTNRLFKLGDFKLGDILSIPYAHTALDSNASANNGRKFVQGKDALVMSERHLAMAVHPYETRRVKVFILETHQGQGPCGKSEEIKQHTYMLRDTTPDPRFRNMVANEPIEVTMDDAKKPIGIHPSLDITNYHIVDMDEVISWVRKVKRADAERLLQAHNDAQAKADQDERTRQGLNDGKPTDLEGVKAEERKLQVARRRIKELNDERRDLVDENYDLRRNTRRLQDSMSRLERESEREIDQLRSRNDIYRDENDWHVLSVTVCRLERKMTRLGLGSVLGGVANADTHDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAT0</accession>
    <name>A0A9Q8LAT0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein CSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758297.1">
        <property type="nucleotide sequence ID" value="XM_047901734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71982464"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02586"/>
    <dbReference type="OMA" id="YGLEWFI"/>
    <dbReference type="OrthoDB" id="10051416at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006113">
        <property type="term" value="P:fermentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029636">
        <property type="entry name" value="Csf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056779">
        <property type="entry name" value="Csf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048636">
        <property type="entry name" value="Csf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085:SF3">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25038">
        <property type="entry name" value="Csf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21678">
        <property type="entry name" value="Csf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 N-terminal" evidence="3">
        <location>
            <begin position="600"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 C-terminal region" evidence="4">
        <location>
            <begin position="2614"/>
            <end position="3276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3167"/>
            <end position="3201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3278" mass="362985" checksum="CAF4BE6540BE7179" modified="2023-09-13" version="1">MTSLRAQPLNAEHEFNWVFDLEVLVIGILSLFFLFYFNRLFATVVSCAIRLYVFRYYKAWIDISALQISLLGGRIFFKKIRYHAHNVTVHVYEGHITWRYWLRAVKDAEVFQDEDAASIGRARSSSTSTGDEQSDVREKEKEKSRARSGSVGKEERATTKPKKELPCRISVRVAGVEAFIYNRSPVYDAVVEATMGKATQASKDATDSEASPRPETAESFESTQDGVEPTRTTTYNTTASTNAAGVEKANIPSFLRIFPIKVECKKAAAALGNESTKNIIVAKTEKGGGTFDAGHAGPLDIWQILMNFEVEDVVVQMKPNRDYKEQQLDQAQRVLREMELEEPQPSRPIRDTCSKILSLCSRLRGAIQRPRSARDSLRTASVRSKSVAGTTHAPLDQLPGQQQWHGLMRYLDDGEINEHEEWSPIEYAKASELVNVPKVTMRFFWDMPGPVPDTLSDGDHLQGPMYEDDINGAAPPAYGMDLGVYGGVVVYGPWADRQRLNLQPIFVPATYVDAIPAKSLKPGELRVCTVFQIKVIVEDDVVLRVPTREESKDAKWKGRADKANPDDPNQQDAVKDEGKHWKKHKHRKRSKAKQGTAAVDARPYGWLDVTVKKDSVVNFNMDMYPRATGYRNTLDLDVKGVEMSSSVNHGLLWRSGPVILDADISQPCSWNSLRKWPFNIVVNDLELFILRDHLFLIIDIVNDWASGAPSEFYTFVPYKYDLDITFNSFCMYLNVNDANIINDPADFDRNDFLTLEGKLHAVLGIPMEHYRPKRNQISFDVLASDMKMRMISPPKSTFHAFVEDKVMATLPKLTLNGSFNGNQEVQVGNVDVLRMDIVGTGLNLKAFGFFVRQLVMVKENYFGDYMHFKTLEEFQGASDDLQEANVKTASFPKPTSINELDVVLCIVAEDATVMLPTNLYSCKEFVRAELPRADLDLRIVSYYLDMGLQLSPVSLLTGTSPDDEDDAPLDTDSSTQFYCSHVELRGHRSFGLPPNEDAYVSQWDIDIGKITGEMSSRFVRDLALAGRALTFTIDDAENALPVVSPAVVLDASFVQVKTDIVRLWMHVGKDALLLDLEPVKVDVAGWASETFSQRVNVIVPLLTLACVDGRSASRHRSRRYRRGKDAVRTYAFLQTGVSLDVVGRSAHFVLETKKQQKHFKLHDQRTNRFPFLIRPNIESEVQPEDELDFEPPAIPYPFPPKPVIQMGGNNRPASIKSLRSFLSHSEFSIKSSSSSLSASIKSSRTIGSAKTRPSLLTRGTEATDISGTSASFHSFASDRPSSEDSGDGQGRRILRTDRERAKFGLLSSTMAFSSPYSEPYFPLELVRPDETNVPAFPEAAASDLNSDTSSVSEMITDPDIDLDAEHTTVMIKVLPGIRAYVEPSVAITASKLIKKVMPIMPEEVMDSFQMDVMGTIQAQTASKLAKSNIVEIQASLASAHLRIVALDESNEHIADQVDLTLTGLENSTRIRNQPQHDAAPLQFLSMHALLESLEVQLIDKMDPAPDSPPTVRLSVDDVLVWLSMANSNAFHLSFHDTNVAVTGSKAKYLTQLALKLIPIVKDIQTRFEDIFASNARRLQTMSYVMTYNGDTVGDPPFMGRLLYVLRVVPTHLRNTDSWKILARFRYILMHLPQDAKNQLEANVKDAKLNIPADTPRDVLESWTQSRNWDVPYVNQTVAFQKLRGDEITQLKTTEQKETSVTFRSESLRVAIEHAKGNSDIILEETSLELENSPPSRPEGLMLVDENKRTKTTVQMHTNTIALALDWGLFYVAEDVISLADQIEEVKAHLESHGHTPTSQKLEEGLLRHDIHAVVSMGTGSIAVRSASLRHVSRADGLKMSFLGTTQASEELGQCESVIVNVDRAVTELHGAESRIWQTLITSPSIYVDHLTPAVGIDTPATVTLAISYDDLQIAITEQVPGILHIVDTIITEEVAKCQRLAEIVQANKRTRKPSIVPNNGTAISRPSTASGQAPKLHVAVLAGNLEMEISLLSTLSYQLKGTAASIRVAPSLAKDQVFSIDFDAGRQEHSFLNTSGDDTHTQGLLDVPPINGHVGLELGQEETAISVVTTIEKVQVDAGAIQGLVGVIIRPEVQDIVSAVKVGVDGIKGHIAEIFPEGETAQRLADPKKRQIVFDTRFALLGIRVSASTPRVVGNSTAEVEFGIGPLHATASNKAMPKEIIPEVRMHIQDIGASLKIKERGKLRPCGNATLTVSLHFKNLAGEQGATTRSLKVSSHGPEVNAYPETASTIIDVINHLQDRIKHLDLSKEVEYLRRMRDERRQTVVQKISGNDEWTEDQELPFSPEDLLAIKTTIELTDIKACWLVDPSFAANKRARVDDLVLSIQSIEFTTRSGNEARLTIKDMMLQLAKKDGKQTRSLNSGLLSEMGFSVGYWKVDNKRHAAIRATGKPLDLRLESRFILPVNALQKSIEMAIDDARKGTATWESTPTSSGAPRSSTTMFDNKHLGSLLVEADFAGAQVYMQGSMPKDRDLSTVAAASQLKYGARHGRYGQFAGDGELLHTTLTAPGIAFKLEYNSLKQQPTINAELMIDASSNMLLPNVVPLVQEVSNSVKELVRDKKPANAPIKQVHVSEVDKPAQKFFDTGDDSIIDVTPAKIFGKTKFDLGFRIAKQEFGLSCQPIARVDAKASLEDFYVTMNTIDSDEHGHFFATSAVLTGLKAQVKHVYSREPTFSYDMESIVLSAMNNKHLSGQSGISAILNVNPTRIVINGKQFQDLLLFREIWLPPEIRNAAAEGGPSSAKPAASRADEFLVQKYQTVAAAAAFPWNATVSIARLSVDVDLGQSIGKSSFTMTNLWASQAKTSNWEQNLCIGLDEMAVNSTGRMSGFIQLAKLGIRTSIRWPEENSEATMQKTPLIQASIGFDKLLAKAAFDYQAFAFGDIEGFDFLMYNVRDAHGKSDRLVAVLDCEKAYVFCTSTSAAQAVGLYQAFDRLIQEKQSAYVQSLRDIEKHVRRESTIVPTRFGPMIPDSPVLEKKSKDSPIRLHTDVVVTVGAICFGVYPSTFFDSQMLKLEANNIQARFAAGLERGRVTSGLGMTLGQLQVGLSSVRRITAVPKALEVTVDEVINSALNAKGGTILRVPKVIASMQSWQTPQSNEVDYIFKSLFDGKIDVGWNLSRIDFIKNMWLSGSKALASRLDRKSLPESAVKIRAGPDPDQPASPPKATSSSSSEEDTGASNQQEKITAEINLPQSRYEYHALEPPIIETPQLRDMGEATPPLEWIGLHRDRLPNVTHQILIVSLLEVCKEVEDAYGKILGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAY8</accession>
    <name>A0A9Q8LAY8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758401.1">
        <property type="nucleotide sequence ID" value="XM_047902452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAY8"/>
    <dbReference type="GeneID" id="71983182"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03304"/>
    <dbReference type="OMA" id="PTWQSTY"/>
    <dbReference type="OrthoDB" id="2021143at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="44023" checksum="7EE27F4DE2754737" modified="2023-09-13" version="1">MERVKSATEQTKVVLKLPSKWVSMYGDFITKNAGAVGQVEGALRSLTYLVPGGLKMSDTSTESLNSGVQLLSLYHDNLLSRALAQQLRAPRHQSPHNRYTRFYCQKSPTYRRTATTLQIVQYTELLLEMMAKKRGEKTRWRLVMLLEAVKAVCRLIIMRLTNSRPLLSPPLPEREVVVEEKNTDDEELASTPSELSDMTAGSERWTMPRTSLTLPPLPNPDDISSYLLSKVLTADDIKPPKALVHRTSGFGEIAEVMFILRPVIYAMAMAYWSQRENGKGKADWRPWLLGLSIEYGARQIAKHDLERRRPGGARGLTQLEREELKKRGWSLAWWTMRGAFYENVTRGIINGFAGKLKNKPVLDMIGTFMEDYDFLWDQFYFPTATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBP3</accession>
    <name>A0A9Q8LBP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lymphoid-specific helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02369</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758174.1">
        <property type="nucleotide sequence ID" value="XM_047901517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBP3"/>
    <dbReference type="GeneID" id="71982247"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02369"/>
    <dbReference type="OMA" id="PNIFTDW"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006346">
        <property type="term" value="P:DNA methylation-dependent constitutive heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18009">
        <property type="entry name" value="DEXHc_HELLS_SMARCA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001315">
        <property type="entry name" value="SNF2 family helicase/ATPase PasG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044753">
        <property type="entry name" value="HELLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47161">
        <property type="entry name" value="LYMPHOID-SPECIFIC HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47161:SF1">
        <property type="entry name" value="LYMPHOID-SPECIFIC HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="232"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="648"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="91"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="500"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="883" mass="98747" checksum="0484CF7FB1274D7F" modified="2023-09-13" version="1">MSSEVATSMESTPPTSPETRDGGASAAMEKEEARMADARRKQDEKRERKLAAEREKDIKGGAEVVDQKYKALEYLLSQSKLYSAIMLQQMTSQEEAEEANDEASKKRAQKKEEKAEQMPQAGQKRATRGAAAAEANAQDAEQSAGTKKELPKRGRPAKNTKGGKIADYMKKEDVQAKAGQTSISEALAEETKDTDVKPSEIGFQELRSAKQPELVTGGLMRNYQLEGLDWLTSLYENGLNGILADEMGLGKTIQTISFLAFLRGKGVHGPFLIAAPLSTTSNWVAEFKKWTPDIPVVLYHGSKQEREELRKTKLRNPGSETFPVICTSYEICMNDRKHLAHLGWKFIIIDEGHRIKNMDCRLIRELQSYQSANRLLITGTPLQNNLTELWSLLHFLMPSIFDKLESFEAWFDFSALKEKNGYEQILSEDRKKNLVASLHAILKPFLLRRVKADVETSLPKKREYVLYAPLTQTQRELYQEILDGNSRAYLENKVVESLSRATTPGSVRSTSSLKRKAANGAATPNKSAKTSRASTPATTGSASGRGRKAKRNKGYEEVSDAEYFKQLEEDDGGSSPVEELDETEEEDRERAKTLSLAKREIAQKKLQNPIMQLRQCCNSPHNFYYPFDLDDNTPVDETLVTESGKMLLLDRLLPSLLEGGHKVLIFSQFKTQLDLLETYCTELRDWPVSRIDGSVAQTDRQQQILEFNEQESDVNIFLLSTRAGGQGINLAAADTVLLFDSDWNPQQDLQAQDRAHRIGQTRPVIVYRFATKGTVEQMLLEKADSKRRLEKLVIQKGRFKNGKGDAGGADFAELQRLLSKDDGERIDIAEGKGLLSDEDLAILTDRSPEAFERAEKGLDVVGAAFKAVQTNKDGNGLLESLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCC3</accession>
    <name>A0A9Q8LCC3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759145.1">
        <property type="nucleotide sequence ID" value="XM_047907171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCC3"/>
    <dbReference type="GeneID" id="71987901"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08023"/>
    <dbReference type="OrthoDB" id="5238236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="757" mass="84614" checksum="E4477C98EE33BFE2" modified="2023-09-13" version="1">MPDLATDVNDLNNLYCHLGLDDTTEDDDLPAATPSKTSSPDKKSPPVAEASAEYEFQAPLDEKLFAVWSVLHDLQSLRREVRSTWRRYSLGHITLLAATVTTDNAMHVAGALDGDLRKEYPDLDSYSAIIDLIGADWYLEELNADRNQHILESAREPNDSHRPVSGPDSTATAISAKELLCIDTWTGLGGFAMLMQSFRTPEHPYFKDRSPETKSSPHPFFCHLYTMAKDFHGMLTSFKKPLDAWTQLGPCLDKATRYILSTATGCAIDTAAVSCLQMYVGIHDALNGNLERGIQEAEEILADVRASFERSDAFLASAAAYSKVFHSQHDTSGSREARTMLTKCEDKEGSATWEWVWTLARPHTTILPDTVIRALPLLAMWCSYITLLAWQTYGSHHSNYGNTILAVSHLYTAARISGHLEVVWEDMEAFINAQNQQSCFLRHSDDKILTLAKHFSMALGLTLTRGNSKGGVTDALEAYYTFLRTYAATQGIRDQDIARQWKDTKRLSPSQLVSTLTEIFLEQETKLRTDLIGLADFCKELLGRVCPLILSTPQMTKEIRGLNNRHFHVLELVYHTLWDAGIAEMRGVERGTDCLRRAASELPTVLSKPGAGTRFLHQKMRLCSQHVPDELQPARRYGDTHIPPPDISAYGISSTSWQDPESTEPCFRVGVGMIEQILHTIPTLDEWIASHGGEPASMQEYQLQVAHYCEKLFVGKFADLPAETQSEMLQRLLTRRRQQGKTASEISLSSGLAWEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCY0</accession>
    <name>A0A9Q8LCY0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758789.1">
        <property type="nucleotide sequence ID" value="XM_047902447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCY0"/>
    <dbReference type="GeneID" id="71983177"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03299"/>
    <dbReference type="OrthoDB" id="652091at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="305" mass="34533" checksum="B734144E02DE3299" modified="2023-09-13" version="1">MTSIPPSATLPGRINTATRKQHTELNRLLINRLPLALPPNVATPLLYAKGIVPFARIFILFEIEWELVTRHVQSKSTAGQTQHDLDVRQWLANLRPHGLARSHRLKNDLQHLRLVGGRNIYSTPELGDKWTKNMRDLMRQKPHVCVAFAWVFYMAVFSGGRWIRQQLANAGPEFWEGKSPLTPSTAAAEKVATSSREDIDQPVPLDISGYSFLSFDSDNDGEELKALFKTRLALAEDLLTPDEKQDIINVAEQLFDKSIFLVTELDAKVRREKILSSMRSLAFPAVLCALLLLVLLRVPWLLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD00</accession>
    <name>A0A9Q8LD00_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abscission/NoCut checkpoint regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759504.1">
        <property type="nucleotide sequence ID" value="XM_047907731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD00"/>
    <dbReference type="GeneID" id="71988461"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08583"/>
    <dbReference type="OMA" id="TRCWYEM"/>
    <dbReference type="OrthoDB" id="5407799at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd19817">
        <property type="entry name" value="Bbox1_ANCHR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044553">
        <property type="entry name" value="Bbox1_ANCHR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="351" mass="38431" checksum="73EE54C7B73DCA8F" modified="2023-09-13" version="1">MPSKDEDLLARLNALKQSSVKLDQTSPSVDVQTPQPQTVEDKLADRLKNLRAGGTPERSNASCGFRDAASELAAQVGDEVGAEKDAIRDWQQQGGDEQTLEELLADLGPDDQWKLDPNDPKDIGSLLKEAEEALPVDVEESQETKTHQGIEPETTDQRTDHDHMNDKDEDQQDEEDADEYIQRVLAEVDLETKYGGQKAEEEEEEDARSDDQVEKGTSSLQLPAAPSTLPEPADSTDKSPPSYDDSELEARFSKLGLNGLDLPSAPTAQPSSSKPKVTASLKPKSNLPTYTDEDIDSWCCICNEDAEIRCLGCDGDLYCQQCWNEGHGPGVGQERGHKAVQYNRRPPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDN1</accession>
    <name>A0A9Q8LDN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759675.1">
        <property type="nucleotide sequence ID" value="XM_047907608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDN1"/>
    <dbReference type="GeneID" id="71988338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08460"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040393645" evidence="1">
        <location>
            <begin position="26"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="13618" checksum="015ECC05F1135BBB" modified="2023-09-13" version="1">MYISKLAALFAASLAVSSAAFRAAAEPPRMGVAIEICGSSPADPKACAVTAANINKLLVALEGTEAFLTSLRFAGDAWNVDIFAVQCRAYGNKEGTIPVGVPFNETYDLNLGTKPVGVYAILCYVIDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE36</accession>
    <name>A0A9Q8LE36_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760068.1">
        <property type="nucleotide sequence ID" value="XM_047904155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE36"/>
    <dbReference type="GeneID" id="71984885"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05007"/>
    <dbReference type="OMA" id="KEATWPL"/>
    <dbReference type="OrthoDB" id="3643498at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="30907" checksum="EFFA87A6B1720790" modified="2023-09-13" version="1">MRLESQPQMSLTCYAMLHNATILGKIFTHLPMHEILTSTQRVCRLWRNVVRDTDKIQKALFFRPMMDKALVYTPNEKGTSWFGRVGRSAEIFEHPLVSRTDTSLRKYYNKTIGGREDASWRKMLISQPPVRCCVVSKWNKGEMDEKFIVARGSGVTLGEIVEAFQQDNIFYMTIQGYQMWQPIWWTKEATWPLLEIGTKGVRRGKWREAKAEDDLVELGKESLVAANRSRVSADRKLTERYQAKKAADAERMKGRGSFGSSRKSGGSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFA9</accession>
    <name>A0A9Q8LFA9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08022</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759989.1">
        <property type="nucleotide sequence ID" value="XM_047907170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFA9"/>
    <dbReference type="GeneID" id="71987900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08022"/>
    <dbReference type="OMA" id="YHDEFTD"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="12">
        <location>
            <begin position="141"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="396" mass="43729" checksum="D76CE776A866F798" modified="2023-09-13" version="1">MARAEWTSTARALADQFDDNDHTLPTSESRRYSSPIWTRRSMDASQTLSRPQSTQAKWMQTAEKWNGRATRQWARLSPLQKAGLVIAGIITNVLLILFLVYGTKIFALMAPIAEKWRNMPGGWLTLWLMTFFVSFPPMIGYSTCVTIAGFVFGMKGWFIMATATVVGSTASFIASRSVLKNFVSRMTEKNKEFAALSLVLKHDGLKLLIMIRLCPLPYSFANGAISTIPTVTWQNFMLATAIASPKLLLHIFVGSRIGALAEGGDKMDTGARIISYLSIIIGMALGVGTGYVIYTRTKARAKQLEAEEAAAATSGGRRESQNSPDYNDDPDEREARNVLRSSRSDISLHPTYADEADLESGYRDEFTDDEDAHERDVFDVGDGDDDDDGSGKTGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGM1</accession>
    <name>A0A9Q8LGM1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761403.1">
        <property type="nucleotide sequence ID" value="XM_047904399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGM1"/>
    <dbReference type="GeneID" id="71985129"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05251"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="123" mass="13440" checksum="FD708BFE117F2C95" modified="2023-09-13" version="1">MAMQLYIRSTRITHGGSCPFFGFSLSFECAKVAGAQTLRRTYSESSDVAMSDRAPLLPRRGLGLGRQSGGAPTPGVQCGGAMKMPMQLASLLALLPLAEEAEAEREGEGWWWRSWSWRGEKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGR0</accession>
    <name>A0A9Q8LGR0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trans-acting enoyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761697.1">
        <property type="nucleotide sequence ID" value="XM_047904815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGR0"/>
    <dbReference type="GeneID" id="71985545"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05667"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="47044" checksum="0FE8ABC376055A81" modified="2023-09-13" version="1">MFSSQHPTRLPSNIMSQDKRQYEAIVFGATGYTGKYTAEHIASHLPTDFKWAIAGRTESKLKAVADELRPVSPDRVQPGIELAQLNKDDLVKLARKTKVLISTVGPYHKYGTAAFEACAETGTHYLDCTGEIPWVYEMTKKYDALAKSTGAIMIPQNGVESAPTDLICWMLVTHIRRTLNTGTAELIDIIHDLNSAPSGGTLDTVLSLFETYSLSQVAKAMSPFSLCTVTPPKQNRSKPLLEALTGIRTDDVLGTLTTSIQGPTDAPIINRTYGLIDGGKFYGPNFQLSTYMRVSNKVNGFLVHLALTFGLAALILPPVRWAARKFVLQPGQGTPREQASKEHCEWRAIANADQSDDSEDPKRAYGRVRWNGSMYDLTGTFLAEAAYCLSRESKTLAHEIGGGVLTPATLGASYLSRLQKAGLETSVSILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHZ8</accession>
    <name>A0A9Q8LHZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762175.1">
        <property type="nucleotide sequence ID" value="XM_047904846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHZ8"/>
    <dbReference type="GeneID" id="71985576"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05698"/>
    <dbReference type="OMA" id="KEIECIM"/>
    <dbReference type="OrthoDB" id="4360026at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="48910" checksum="4CCE97F6BA034487" modified="2023-09-13" version="1">MASQVGRACAAAGYTELYKELAILPEIHIAEEARDSGNEEIYRSIMAAPVKYTVMNGYQRALNLESPVAANMNVDTAVRWMLQVKQKFRNLADEDDMEDWDIADIMEHGFDEQTFDITEEMCLDLIGMPPEDIEKLRPRCDLLSLLIEPLPQDLPTADKDMLICAAAYYGNTDRYVRLRRPKFVRKEIECIMRGVYHNTLYAAWWSKQTLPQEPKIRMAIEARFITNNELSRVQSAEFVPPYLIWFPTIAKPATYRALAQLRPDMLPQILRACIVAASGLNGYNELFDELVHLSMPDEALVHEADVSGDAHYKQMLLSRIAEVGLVKLPWPHDWKPYAQQCLQSSSNQVTKYNYQLAPGGSFDMLYNGNQCDAGELELTACLPDAWKIGDNDEAFWRELDYVEWPPRDLTSGQSRRTEQLDRLDRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIR3</accession>
    <name>A0A9Q8LIR3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762496.1">
        <property type="nucleotide sequence ID" value="XM_047905414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIR3"/>
    <dbReference type="GeneID" id="71986144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06266"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08252">
        <property type="entry name" value="AL_MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014182">
        <property type="entry name" value="ADH_Zn_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051603">
        <property type="entry name" value="Zinc-ADH_QOR/CCCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154:SF1">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="25"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="369" mass="40101" checksum="2D2B531BE902D34D" modified="2023-09-13" version="1">MISVDVRTSSISMSSMKAVAVSDYGTIENLIATEVAKPDKPGGHDLLVRVKATSVNPVDTKARNGTYDDYPDYYKRTPSVPHVLGFDGADIVEHVGGKVQDVKVGDEVFYSGSPIRQGANAVYMLVDSRSVARKPNSLNFAQAAAMPLTWITAYEALVERLEIKEGENAGILIINGSGGVGSVASQIARQLLRLPVVVTTTSREETTAWSKELGATHTVNHREDVVQQIKDLKLQVPLKYVFITHTPASKYIRDSASICAPFGKVCSIVQDQEIPMYGTEWMAKSLTYVWCLLGTKPYYGVQLDSHGKILKQLAEFVDSGKIKCHHTQTLPLTADGLRKAHEQIEAGGVKGKIALAVDAEGLDPQQAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ00</accession>
    <name>A0A9Q8LJ00_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ00"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_06307"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="273" mass="28634" checksum="20C584F3AC165AE5" modified="2023-09-13" version="1">MAGTCKQWSVMGHDGTNSLHCGQVLVQDRTFHTIHGMATRTDIVVHYPFDLKPNVVPGSDGAGTVMAVGKHGLMAGSMTAKTARTGLGGSLDGTLHTHGVFDEQGLTAWNALFGMVGKSFSAGQWLLTCKVIATTSSNEKAELLKKLGADHVLNYRTSNDCGDIAKSLTGGEGVDLVIEAGGPTTLAQIVQSVKLDGTISIVGSVGGQSLFTARGVWVGSRTQMEDMCKLIAASPDSLKPVVDDKIFSLDQVKEAYAYLGSGQHIGKVCVQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ26</accession>
    <name>A0A9Q8LJ26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762678.1">
        <property type="nucleotide sequence ID" value="XM_047905022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ26"/>
    <dbReference type="GeneID" id="71985752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05874"/>
    <dbReference type="OMA" id="STNQHGQ"/>
    <dbReference type="OrthoDB" id="2559882at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="9673" checksum="A988BB26EB79D0A5" modified="2023-09-13" version="1">MSSTNEHGQDKSHAIDDSAVPGKVQEAAPKGLEDSPPESVHPTGNKGDQSTNKSHALGGGEESVVPQKIQEKLPESVERAVPNVIHNTGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJS4</accession>
    <name>A0A9Q8LJS4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein plp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762870.1">
        <property type="nucleotide sequence ID" value="XM_047905786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJS4"/>
    <dbReference type="GeneID" id="71986516"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06638"/>
    <dbReference type="OrthoDB" id="10257948at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="24220" checksum="778A5B65C717B410" modified="2023-09-13" version="1">MSTIDAHVAKVLDKQRPGQDSDDEDALIAELEDDEDNAFSALREQRLQQLHSEMARAKMMKETSHGTYMEIKDEKQLMDITISERLCIVHFMKPDFNRCGVMDEKLRILAEKHFDTRFVSINVDNAPFLVVKLGIKVLPCVIAFKDGVGIDRIIGFEGIGYKPDSFTVAELEARLLACGVLVRSKMNDGDDHRRERKREEREEDVYADDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LKE3</accession>
    <name>A0A9Q8LKE3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_06347</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762719.1">
        <property type="nucleotide sequence ID" value="XM_047905495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LKE3"/>
    <dbReference type="GeneID" id="71986225"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06347"/>
    <dbReference type="OMA" id="DYPFGRL"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="28835" checksum="D1D764852B1E062D" modified="2023-09-13" version="1">MAPIILYPHLNTHHPLFLLPQEIQDLVFSFVFSETNLDISTTRDAELRIFEKHLILRRTWPVPPPSWKGCRNVFRTCKVFYANGLDFLYSQMSFSIRINGDDDDPGQTRSRLHSDYPFGRLDECLPLQYLRRVHVSMSAGSIQDLVRLETRVKAFDVAVKESPKLCVTAIRLSLGRLFVTETVFWLLERVMGIMLRHCSADGMQDEQLFVKIFSNPGNDIPELFLRGLAQMVRKVGRNASVVSYSKGMVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2X9</accession>
    <name>A0A9Q8P2X9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755513.1">
        <property type="nucleotide sequence ID" value="XM_047900655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2X9"/>
    <dbReference type="GeneID" id="71981385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01507"/>
    <dbReference type="OrthoDB" id="648861at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="55297" checksum="FE49AAB7E248BC04" modified="2023-09-13" version="1">MASSHDEAAEHLLEADEPGPPSLNRFETDDETSGLTEREHSKARRLLYISHFLSTWNSRLFEFGAFLFLATIYPRTLLPASIYALARAASAAILSPYLGSYIDTGNRLRVVRLSIVGQRVAVTISCILFFLMANVNHLRDDQLLSALLLALLSALACVEKLAWVLNTIAVERDWVVTVAGENDERLRLLNSQMRRIDLFCKLVGPLAIAFVNNASPSYAILVTGAMTLLSVLVEYFAIARVYNMVPALKLPKTTSQRPHSQHNLWTTIKEAVSGAVTYARHPAFLPSFSLALLYLTVLSFAGQMITYLLALGLSSGLIGVLRGVSAVFELSATWFAPKIMARIGPVRAGIWFINWEILCVAIACAFFWIDLSPAYTAIGTVSAVIASRVGLWGFDLSAQIIVQEEVELENRGTFSSQEFALQNIFEMLAFASTIVFPRPADFKYPATVSAIAVGIAGILYATFVRARRGHLIHLSQCVDRKGPHRNPHHWWQRIPNSSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3K1</accession>
    <name>A0A9Q8P3K1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756379.1">
        <property type="nucleotide sequence ID" value="XM_047900859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3K1"/>
    <dbReference type="GeneID" id="71981589"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01711"/>
    <dbReference type="OMA" id="ESPTHMP"/>
    <dbReference type="OrthoDB" id="5234213at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10498" checksum="F0DFF95CF00EDA64" modified="2023-09-13" version="1">MAPSDKKSLKEIAQDSNPSQLGDPVSLKAETSNTEPTDQDRGAKGGEKSLKQIAEDKMKTNPTQLGDPVSLKAETSDTEPTNDDRGARGPTKSSGKPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3T3</accession>
    <name>A0A9Q8P3T3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756383.1">
        <property type="nucleotide sequence ID" value="XM_047900103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3T3"/>
    <dbReference type="GeneID" id="71980833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00955"/>
    <dbReference type="OrthoDB" id="5413188at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="48481" checksum="4E57A896FBFB7C79" modified="2023-09-13" version="1">MDERQQPAHSSDQIRRPGHTSAMPSRSAESSRRMHPDTESLHGVMSRVDSWIDVSSQPSSSSLSSAGEEIVTTGLRVQDDPRTRRRRTQRSDLPTHLHITRTQSAGGTSSQEEYEESESESDRIMTSSGEGPMLAAPLSRPSMPFVQRAQQPSAQVSATVQDSDDDDENRTAINYPINNDTCFTPLPNAFSHPPSAGQARHASQPVPDSYFPATRSIPATRSSTRQSLPANMERRHSHLPHNVLSPSFNAAAEHDEALRASLTSLLSVAAAARGLPKVRPQAAETALPPRSNRVDPSTFRMVPESALPVNSPTQFQEPTFKPTIRRTSTNSTSTSDRTKDHKRKAVAVPTRSASRERRALKKARRSASTEDLHVTPTLLTWVVSAGIVVCLSALSFTAGYTVGKEAGRLEATELMADEQLRTCAREAGRSSLGLKRSLARSAIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4D1</accession>
    <name>A0A9Q8P4D1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatase PP2A regulatory subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01654</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757100.1">
        <property type="nucleotide sequence ID" value="XM_047900802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4D1"/>
    <dbReference type="GeneID" id="71981532"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01654"/>
    <dbReference type="OMA" id="NRVEAMQ"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000011">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="12"/>
            <end position="50"/>
        </location>
    </feature>
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        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
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        <location>
            <begin position="166"/>
            <end position="204"/>
        </location>
    </feature>
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            <begin position="178"/>
            <end position="275"/>
        </location>
    </feature>
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            <begin position="205"/>
            <end position="243"/>
        </location>
    </feature>
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            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
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            <begin position="279"/>
            <end position="355"/>
        </location>
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            <begin position="285"/>
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            <end position="362"/>
        </location>
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        <location>
            <begin position="363"/>
            <end position="401"/>
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    </feature>
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            <begin position="371"/>
            <end position="533"/>
        </location>
    </feature>
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        <location>
            <begin position="402"/>
            <end position="440"/>
        </location>
    </feature>
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        <location>
            <begin position="519"/>
            <end position="557"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="620" mass="69342" checksum="1FC309FEDD2EEF9E" modified="2023-09-13" version="1">MEEQGQNDELYPIAVLIDELKHDDVLLRLNAIRRLSTIALALGPERTRDELIPFLDESVEDEDEVLTALGDELGNFVEYVGGPEHGHVLLSPLENLATIEEPLVRDKAVESLNKICDQLSQQQVEQYFIPLTIRLSKADWFTSKISATGLYNTPYTHATAQSQEGLRQQFAQLVHDDTPMVRRQAANNLAKFVKSMPAAVVIEDMIPLFQHLAQDDQDSVRLLTVEVLIAIAEAVPKEQQTSHAVLLTALRSLFEDKSWRVRYMVADRFEKIAKAVDEEVIARDLVPAFVKLLKDTEAEVRSAIAGQIPGFCQLVDRQALLRDIMPAIEDLVSDSSQHVRAAFGNQISGLAPILGKQETTEHLLPMLLQMLKDDFPDVRLNIISKLEQVNNVIGIELLSQSLLPAIVQLAEDKQWRVRLAIIQYVPLLASQLGVKFFDEKLSSLCMSWLGDTVFSIREASTQNLKKLTEVFGVEWASEAIVPKVAAMAEHPNYLYRMTTCFAVSILAPALSLPVLAQSVLPILNQLVADPIPNIRFNVAKSYAVLIDILKRLPDDQNTTIVELEKKGSTNFPGSERGAQLIREEVIPPLEKLMQDDDVDVRYFATTANKAWTDTENAMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4D9</accession>
    <name>A0A9Q8P4D9_PASFU</name>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_01897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901045.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981775"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01897"/>
    <dbReference type="OMA" id="VELWLFT"/>
    <dbReference type="OrthoDB" id="2290221at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013745">
        <property type="entry name" value="Bit61/PRR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428:SF2">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08539">
        <property type="entry name" value="HbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="293"/>
        </location>
    </feature>
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            <end position="382"/>
        </location>
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        </location>
    </feature>
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        <location>
            <begin position="721"/>
            <end position="776"/>
        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
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        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
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        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
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            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
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        <location>
            <begin position="354"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="847" mass="89478" checksum="7B7A0080CE4F2692" modified="2023-09-13" version="1">MDNSDLTPPPRPRSPTGNRSQSSLSQGSLRSESSLSTASNESREIIAQSANKRSPYLQQQPAARPATAGGLTPSQSSITLQGIPRHAAQARGSVDGTYRMASPGMAGQQFGHRARQHSQGFFEPSLPHATANNNGLSASQIAAQAAMHHISPPPSQVGQERKRSYPGLAPINTAGHPGSRRPSDHHSPQLSTTTGLSYSNGTVGGNRLAATTAANVAFPNGRSPLPSPGVPPPPVPSSFALGPPPDKEPKSKSSKMKLFKPKNIALSKDKESKAPPAFPSPGKTPSTSHFLRPGFANASTTSLVDPISAASSIYSSANASTSTLVPAISEKDKEKRHHFLSRQKNKLRDEPTQLPLSSAHSNSQATNPDKPQPLYSFAPDSPGPSTFAKSMSGFDLRHGGRALREKKKEEKAAAAAANLNLTQITSNTSGGTADQYLGPSSYDNTLTGPPSVNASVFSFPSDTTLPVTAQAFSNIGAQMGLPGIGPDDAWPLLKARLLNLFSGENLRTPIEDFNALVSVHIRRCIQRRSPVVLVEDVRELLQTGFSSLAQTLRTIPDDRLVTNLVEMWIGVYGAILPFLQAVFLPLELEFKGKGTLMTPREAQEFWGAVPESLKLDERPSSAGGSGRMANLADELEIRRITLIAFRDTVILPKHESLMNIFSRLSLDNINAGVSPEAGTKSREHARSDPATTGAERPGTAGSLSPRLSSFNSQGSTLLDAASNSSGGAMSLASRSRATSNTSAGSFGTSMPHLNSPLGGPGSFGVTSQPQASPVPLADPAKVTETVARMLQCLYVLASCRTGDVAQGNVERLTGALKYNWLGRGRTGRDRRGWVGMKAGQRVGLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Q2</accession>
    <name>A0A9Q8P4Q2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase ucsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757328.1">
        <property type="nucleotide sequence ID" value="XM_047900240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Q2"/>
    <dbReference type="GeneID" id="71980970"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01092"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="100"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="35312" checksum="A8BFB98EE4614A00" modified="2023-09-13" version="1">MMRPCCTARSKPIAILAHLSSITARHQQFKPVNMARLDEHTGDDWGEMAKVYKKLTVGTSAKPIRVILDRLNALVPFSEASGIFDDGTGPGPIISRIIEEYGPTLPKSCTLTATDFAPGMVEQVKNVQQEELQKDPASPWNRVSVSVLDAMDLKGIPDDSQSHLTAGWVFFMTPDPQKCLTESRRVLKPGGVLGCSSWKGNQWMDIMKLVSVIRPDKTLPELPKEWTSAPAMKVELEKAGFRDVNSEDVQVEMSFDRYEPFLDLLTTKMPMMINLVKDFSQGEMERLRQLMLEKTKEMAPSEPGILYGAALVATGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P503</accession>
    <name>A0A9Q8P503_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757864.1">
        <property type="nucleotide sequence ID" value="XM_047902671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P503"/>
    <dbReference type="GeneID" id="71983401"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03523"/>
    <dbReference type="OrthoDB" id="5242705at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="66908" checksum="3789FD4899B51357" modified="2023-09-13" version="1">MSHPRDTTPPSRDKQVPSPWNTRGRLQHTIRLISLNLWLWELLGLLTSTLCIGAIICILSIFNGKPVPDWSYGLTVNGLVSILAGIAKASIVLPTAEAISQLKWYWFWNQQRPVVDFERYDSASRGPWGSLVLRCYPRLWNIVSLGAGLTIAAIAAEPSLQQIPILSLSTVATGNASVSRIISITGHENDGASNPILNMSMKGAVYSGIFDTELSNTAAIMPVWPTGNCTWPRFSSLGVCNACANITSRVFVSSTNPDYPVWTLPNGGIGSGLNQSISLLGGDSSAGWMVAGSWNSLAFDQKFANQSIIDLSFIYLPPVNATLLRDTNSTRANAAECVLWPCVKTYDAVMANGEYKETVTDIWPPVNATLSENPALKSMCNCTYREGCNELSPISQYSTCNVLIPRKLELRPPGDDTSYIYNLDSYNLLRNWLGFVLQLVYSSGYNTQFLMAQSRNDVPQAFYSTQLEHANATQAWEMRGPSAIMERVATSLTNHVRSAGAEEQSVAGTAFTAQNLVHARWEWAILPLVLLGLTVCFVVVTITLTARRGLPLWKSSSLAHVLHGLDDDSSDAMTANRSDQLESKAKGFTMKMDLELERWRLRGLRRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5G5</accession>
    <name>A0A9Q8P5G5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758270.1">
        <property type="nucleotide sequence ID" value="XM_047902463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5G5"/>
    <dbReference type="GeneID" id="71983193"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03315"/>
    <dbReference type="OrthoDB" id="5388417at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="18037" checksum="5309745D67CBB4B4" modified="2023-09-13" version="1">MVNLLVVLLVLLIFALLLVAGLLFLRHRRRVARKQLALPQYDEKRLSNASTLSSHRRVMVRPSESVYVYQEKQSLVENSDSPPQSPLPEIHITFPEEVDAAGKRKSGRVVVVRVGDTGVGLEPVDDTLPAYRQNEGDRFQSLDLERIGGLVEKARNAPSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5P1</accession>
    <name>A0A9Q8P5P1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758569.1">
        <property type="nucleotide sequence ID" value="XM_047902926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5P1"/>
    <dbReference type="GeneID" id="71983656"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03778"/>
    <dbReference type="OMA" id="CSSAWVL"/>
    <dbReference type="OrthoDB" id="2865667at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="134" mass="15104" checksum="8AE6D3F65EAAA146" modified="2023-09-13" version="1">MASTTALYDEILQLEEKTWRALQGRGSDLVPFLTRDCIMMFPMGMKVSARTEPSVHEILHSSAFVPWKTFDLRSIDVTPVGPEGAVISYRAIATRAPASNDDPRDVEFDALCSSTWRFEGGKWRMCFHQQTMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5S3</accession>
    <name>A0A9Q8P5S3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_03644</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758781.1">
        <property type="nucleotide sequence ID" value="XM_047902792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5S3"/>
    <dbReference type="GeneID" id="71983522"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03644"/>
    <dbReference type="OMA" id="HSFCNWC"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="164"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="379" mass="42577" checksum="D3D701C717C7C3CA" modified="2023-09-13" version="1">MAPPMKAPTNMWSKGSALVERLKEFYTGKKETPPLISERTALLCAIGFTVLYVAPFYLSKTLRTSPLVSRDSPAVIRARVRAVGLSCLASTVIAVYVLATYGHATPRDVLRLFAMWPVDPTDCLKVLGLVCVLFVGPLYETLIADSAWRDLSFKAIKENFWDHLPGFRNYVVAPWCEELVFRSLVIGLYQLAKVSPTRIVFVTPLIFGVAHVHHLVEFCQSRTPPGRIIPPANVILMGVVQSLFQFTYTTLFGFFAAFVMLRTGNVFASVTAHTFCNCMGLPRMWGRVGQFEEWEGHNVTPDVAQGKRDDSLDQVRVGNSLMQEQSEDEKHAADAMKTRKRNLGVGWTVVYYLLFFGGAYGFYRLLWTLTESRNALVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P601</accession>
    <name>A0A9Q8P601_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758812.1">
        <property type="nucleotide sequence ID" value="XM_047902746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P601"/>
    <dbReference type="GeneID" id="71983476"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03598"/>
    <dbReference type="OMA" id="FKAGANW"/>
    <dbReference type="OrthoDB" id="3357002at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="35987" checksum="E4BEEAC73C05D77A" modified="2023-09-13" version="1">MASAQDMQRPPGPPYAPTTAGIGGRSTVIPDIPILAVLLLFYIGGAVSNMTIFQRNRRRQHKFVPSALLFGFCMARILTCCLRIGSAMKPQNISLAIAASIFVNAGILIVYIVNLIFAQRILRARQPYLGWSKAFKIFYTMIFGLIAVALIVVIVFIVISFYTLDQHLKQVSRDLQLAAITYLLIVTMVPWIILAVSFALPEAEDADTFGVSDKSTHYKALVLAASSALCVIGASFKAGANWEAPRPASDPAWYQKKAAFYVFFFVLEIFIIYLLIITRVDKLFWVPNRSRGSYKVVTEQDVSPLNTPRIGSSGQDVIVRPKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P625</accession>
    <name>A0A9Q8P625_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="5">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF6</name>
        <name evidence="6" type="ORF">CLAFUR5_03801</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <text evidence="5">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P625"/>
    <dbReference type="OMA" id="WCAFCGM"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="26326" checksum="4D61A58AC86562B5" modified="2023-09-13" version="1">MAVRASFENSNEVGVFSTLTNSYALVAVGASENFYSIFEAELQDVIPITHTTIAGTRIVGRLTAGNKHGLLVPTSTTDQELQHLRNSIPDTVKIQRIEERLSALGNVICANDHVALVHPDLERESEEIIADVLGVEVFRQTIADNVLTGSYMALSNQGGIVHPKTSIQDQDELSSLLQVPLVAGSVNRGSPVVGAGMVVNDWMAVTGLDTTATELSVVESVFKLGEGMAPGAINTTNKETMVESFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6C5</accession>
    <name>A0A9Q8P6C5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759053.1">
        <property type="nucleotide sequence ID" value="XM_047907195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6C5"/>
    <dbReference type="GeneID" id="71987925"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08047"/>
    <dbReference type="OMA" id="KLPCYES"/>
    <dbReference type="OrthoDB" id="3641178at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="512" mass="57525" checksum="EE33B537B49571E5" modified="2023-09-13" version="1">MNLAFVLELELATPLDKTFRPTPQSLRTMAATRELEMSDHYPIELRYIKALFVQRQYRKCIQACRDVTKLADSRQHEPALQKTFISLYAGLAHDEVARSMHQNSITKLPCYESAEQLFMQALDALPSYEDARHQCSQTPPSDPEPVPDTASATEPYRSPSIDEPSFGDLNRLSRASSSVLSSPPIFHRHSQQSLSVRSSFFSPGASTSDTDDLESHDSFSELLTPTRLLNRDFSRISLLDIANSSLPRATSRMSLIEPPKTPQRKKSLSQGLMRPIRPGSPAKQFHIPPTLPYSGAPQRMPSRLPQLATRTKTETRLEIARVDSAMGESSFVTCPEPVSPMSQTGSDVNLSDASTVSALSPPLTPTHPARSSSVTTLGPSEPPLLDESKFLRFTDHLRAMRTQLESHIVMVQQAQDKLRQVQTERRAQRATQPARSKNTARDYFSSPAQLSPKDNSVVRLQQARSFWSFIPEDIKADEKKRRIQAGRDRGWKKERFQPGRYRDLCEKALAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M3</accession>
    <name>A0A9Q8P6M3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain dehydrogenase srdC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759472.1">
        <property type="nucleotide sequence ID" value="XM_047907319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M3"/>
    <dbReference type="GeneID" id="71988049"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08171"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF12">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040235657" evidence="4">
        <location>
            <begin position="23"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="28130" checksum="A1342E7D8F270937" modified="2023-09-13" version="1">MMINLFPGVALVIGAASGIGQATAISFVSEGCRKIVISDLNEKGLQETKNLIHQADEWGDAQVEIVQVNVSDEAQVQALVDKAVQAFGRIDYAVNAAGTLSRNTKSHETAPEEFDRINGINYRGCWLASRAQLSQMLMQDPLETHDGRPGNRGSIVNFASQLGIVGRPAAAAYCASKAAIIGMTKCDAIDYSKDNIRVNCVCPGVIDTPMTRPNMDVLDSAISIAPLDRPGTAQEVADAVLFLSSSKATFIQGSALVVDGGYTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6R0</accession>
    <name>A0A9Q8P6R0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="7">PME-1</shortName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_08059</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759577.1">
        <property type="nucleotide sequence ID" value="XM_047907207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6R0"/>
    <dbReference type="GeneID" id="71987937"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08059"/>
    <dbReference type="OMA" id="VMVCHHG"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="10">
        <location>
            <begin position="105"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO15211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="42410" checksum="FEFF34EF65824311" modified="2023-09-13" version="1">MSGLFKQSVNGAAPPNEHLRPPPMPIATPQHGDVDDYPSSDSSASSAATVDTIRPSSREQAAPATHWTNFFDQELYLEEVTGEQKAVYHAYLTLPIDLKKDPLFICHHGAGASGLSFAIFAQQIRARLPTAGILSLEARAHGSVVTNMETQEEVIDYSLATMTNDAVSMIKLTASTLGWDSLPPTVLLGHSLGGAIVTTLATDHFKVFGSSFIGYSVIDVVEGSAIEALGHMKTYLSSRPSMFSSIEDAVTWHIRSRSIRDHPSAEASVPSLLIPSPSGNGKLIWRTNLDATNPWWEEWFTGMSKKFLSGRGAKQLILAGTDRLDKDLMIGQMQGKFQLVVIPEAGHFVQEDVPEKTANLLIEFFKRNDRSQMVLPPKVSDLIAQGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Z3</accession>
    <name>A0A9Q8P6Z3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760011.1">
        <property type="nucleotide sequence ID" value="XM_047907773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Z3"/>
    <dbReference type="GeneID" id="71988503"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08625"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="144"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="29841" checksum="F1DF753E06F76106" modified="2023-09-13" version="1">MEPDTLSPHNDNTEEPRSDGCENMSCVREAPRATDTIHGTLSVNLHLTTAFHPSGAAESHSYTPAGVVQDATDGNGPSDAMSFRPYSSAYTDQQAAGLRMGAEPPIVIPANDSSGAMDLSHIYPGDGPHNFDFDAFLAAQPEVQDTSEELPHQENRPNPPGASSGAGHTAIEPPDAAPLARDQANDTLGPMDVASLDIGDVLDDFDFDVFLNGGDSYQCDQCSQRFDHDLDLKRHERIHLAIKPFPCTRCEKSFSRKDALARHLLVKECGTEAVSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P732</accession>
    <name>A0A9Q8P732_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759833.1">
        <property type="nucleotide sequence ID" value="XM_047907662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P732"/>
    <dbReference type="GeneID" id="71988392"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08514"/>
    <dbReference type="OrthoDB" id="3440281at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="295" mass="33617" checksum="0A2659ADFC4D5D10" modified="2023-09-13" version="1">MDPIIEQFCREAYNELVDLYYNDEFEACIEKAYKLLDDEGLPRYHRMKTWMLLGNCLVDWEEANECFVKAQEMWWTVRREHTFCEDAHADEMLEELAGELEELNAVLDADEDKPEGEVSGGHDGPEALRKAKEEVVGLWKTEYFLREFDLAGEKPPGQLVNPVALVAAEVACHAGSTCRHLIAAPIEVVDLRRSRAGSLGDHAITHHIPHYISAHRLLRRALRATAEDLKDTRASETTRNDSHKAHWPNKNALESRSGGRLVEGKHMEHGIGYTLSRYCLKSMVCFSYLRVEGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P733</accession>
    <name>A0A9Q8P733_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760116.1">
        <property type="nucleotide sequence ID" value="XM_047904176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P733"/>
    <dbReference type="GeneID" id="71984906"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05028"/>
    <dbReference type="OrthoDB" id="5357075at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="37628" checksum="26ECBB5EAC4AB948" modified="2023-09-13" version="1">MLGWPILVHYCDSCNYNTPVQYTGTVREQQHICTHCGVRQRGAEVVGESKGVMNVNQQDELAQLFAQSMHLQQPQHRSQVVEQVQPVSEKTVDSPIHFASAHYTPNTAHMRAETQSEPAQSPPPPYREALMPDAMADMLRQNSIDPSALLPNQVNLFLNADYEQRLRLLELWRISPPSYPHEQQLHQHWAQGSVEKEEHAARDRYEQQMQQRSVRQEEHMFDTFVPEPTRMRSASISAGTVTIKPVEAEPYIVNGYEIAAASSRAVEPVYAAAGLWSAPSYEATVQQASMEDQYGMIEQIRCHADWDRMNQQQFRGMHGPVSGDDSMDMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P743</accession>
    <name>A0A9Q8P743_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Cytochrome c oxidase subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Cytochrome c oxidase polypeptide VIIA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_04390</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the fungal cytochrome c oxidase subunit 7a family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760146.1">
        <property type="nucleotide sequence ID" value="XM_047903538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P743"/>
    <dbReference type="GeneID" id="71984268"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04390"/>
    <dbReference type="OMA" id="ASYWWWG"/>
    <dbReference type="OrthoDB" id="2317211at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22888">
        <property type="entry name" value="CcO_VIIa_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014368">
        <property type="entry name" value="Cyt_c_oxidase_su7a_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28264:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28264">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000283">
        <property type="entry name" value="COX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO15780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="62" mass="7092" checksum="F91149F9D3A3FBFF" modified="2023-09-13" version="1">MPIKPITGMLRRGLVLDLSVAFGLGTSFGYFWWYGFHVPSVRRRDQFYAKLEDERAAALGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P833</accession>
    <name>A0A9Q8P833_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761029.1">
        <property type="nucleotide sequence ID" value="XM_047904242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P833"/>
    <dbReference type="GeneID" id="71984972"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05094"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
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    </dbReference>
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    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="51"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="156" mass="16680" checksum="9F40A5D8109A8E00" modified="2023-09-13" version="1">MFKTTTRLFKPNAIRNFTTTPSRPFHFSAANMGVTKQKLQDGDGKTYAKAGDNITMEYTGTLFDENAPNKKGKQFDSSVGRGDFDTRIGVGQVIKGWDEGVLSTDGGMSLGEKATLTITGDYAYGSSGFPGLIPANATLVFDVQLKAINGNRAPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P836</accession>
    <name>A0A9Q8P836_PASFU</name>
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        </submittedName>
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        <name evidence="6" type="ORF">CLAFUR5_04792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO16739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="85" mass="9578" checksum="39024E2B4738B17F" modified="2023-09-13" version="1">MPKEINDIKAFLEVSRRKDASSARIKKNKATGQTKFKVRCQRYLYTLTLKDSDKADKLKQSLPPGLTVTETPKKNAKGKHTAKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8D6</accession>
    <name>A0A9Q8P8D6_PASFU</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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            <authorList>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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    <dbReference type="GeneID" id="71983998"/>
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    <dbReference type="OrthoDB" id="4217619at2759"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO16907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="29454" checksum="0F83EF80AE2E875E" modified="2023-09-13" version="1">MMEQSTMSAQPASAPATKQPTGFFDLPQECRDMVYLQFRPFAYFDITQQPKAIHQPSIAKVSRQVRAECLDIFYGDSKFMLDMRGWKHSAYPKSWTPNKIFDEWIMSLGDENTARLRNVWFYLNNSMVAFTIRNDKPRITFKFKQTRSGSSYAEIAEDAPSGHTFKIAMERARARLTYRVNEVMDAVKERPLTVTDYKGLCKLVEDIKPTLCTRIGIGWKGAVLDKDPSVHTNVNIHRKQCTECGYYRIGDSMTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P952</accession>
    <name>A0A9Q8P952_PASFU</name>
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        <submittedName>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO17788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="20038" checksum="D780EB5B9854F289" modified="2023-09-13" version="1">MSYYFTIIGTRDNPLFELDFGTSKVGGDGIARFREEAKHMNQFIVHAALDLVEEAQWTTKDLYLKKVDSFQNNHIHTFLTGGNVKFMLLMNPDPSVTTYSSYQTSPPSRPNTARQSTLIAANPTSQQTEEAVRQFMFEVYEAWMKCIMNPFYHVNTQVTSPVFRSRVSTAAKKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P970</accession>
    <name>A0A9Q8P970_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
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        </lineage>
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    <reference evidence="2" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762351.1">
        <property type="nucleotide sequence ID" value="XM_047904685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P970"/>
    <dbReference type="GeneID" id="71985415"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05537"/>
    <dbReference type="OMA" id="NRICTEP"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040487753" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18174" checksum="F82BF3D30D2C814F" modified="2023-09-13" version="1">MRLKILGLLIPLALLTLFARLVSAGYHFQINVQRMKPNSLCPEGKTGKRVVINSKEGHNCYTWKEHEVFNGFAYGVAGYSEWKAPKPEEYGRCIIHSYEGPFCTGRYLGGIDHANVPTQPWAAGIGGCFQSQVDPSDPYDRPGMTRSMSLTCHKKADRGLLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P998</accession>
    <name>A0A9Q8P998_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-aminomuconic semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06152</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762410.1">
        <property type="nucleotide sequence ID" value="XM_047905300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P998"/>
    <dbReference type="GeneID" id="71986030"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06152"/>
    <dbReference type="OMA" id="QYDNAGQ"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07093">
        <property type="entry name" value="ALDH_F8_HMSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="45"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="501" mass="54402" checksum="06FEBCC6D0217635" modified="2023-09-13" version="1">MADAVLNQLWDASNHEQALRQVSYSTVTPIKLTNFVDGFFSTSSSTSAQLDSVNPQNGKSYAKVPNSSANDVDAAVLSAHRAFSSWSKTSPAARSITLNKIADIIASRRNIFATWESIDQGKTYERAQIEIDRAVSNFRYFAGYILHQESAARFTDTNHLTYEHHSPKGVFALISPWNMPLYLLTWKIAPCLAFGCAAVAKPSELTSVTAFLLANVLREARLPNGVINIIFGAGAPTGKALVNHKLVKGISFTGGTATGIQIRKDTAEAIGKHLSLQLGGKNPTLVFADADLAEAVRTSAIAAFENQGEICLCGSRTYVERSLFTTFVIHFVLHVAANYKLRCNVGAVVSAAHYDKVRGYLALAKKEGAKFELGEVPPKQQQGGYWIPPTILTDVASRSSVMRDEIFGPVVTITPFDSEDEAINLANDNPNGLAAVLLTKDMSRTRRVGEQIDAGLVWVNCWLVRQLATPFGGMKSSGTGREGGAYSREVFTNVRTLHIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA80</accession>
    <name>A0A9Q8PA80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkaline phosphatase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763108.1">
        <property type="nucleotide sequence ID" value="XM_047906386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA80"/>
    <dbReference type="GeneID" id="71987116"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07238"/>
    <dbReference type="OMA" id="IHGPASF"/>
    <dbReference type="OrthoDB" id="2100241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF2">
        <property type="entry name" value="ALKALINE PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G03860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="1">
        <location>
            <begin position="303"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="668" mass="74716" checksum="579067B53E05B0B5" modified="2023-09-13" version="1">MAVGPFGEACKVAAAGSSLVLRACAWVFLRWIPGHHFPPLILAAFAVFVPAFYFTSQYISPWKVIADEVKIQTRPTLPDDVVDVDARYADGHVITPGEELVVEEDIELEEEDPQIFKTLATGLPSSASTFWSAITFLINAALVAMTIDLVYRAKTFYPQHDLSMARVGFVSDSSVKLLVREPDATKFPVFASYRYADPPLKSSLGGMLPDTAWRSAGQLDWLDNKTDFTGAFELKSLKPDTRYQWVVSNNHSGHFTTAPKTGQISARAENNDQFTFVHSSCIKLNFPYSAFEHPLSAPGLRHLARALKEVKAQFMLFLGDFIYIDVPHRHGITLEDYRREYRQVYSSPDWPAVSEDLPWIHVYDDHEIQNDWSGNTTDVFLAANDPYEHYHTSVNPPAHRKGETYFSFTQGPATFFMLDTRRYRSPNDATNGSDPITGEATKTMLGAQQLADLLHWLARPEPAGVKWKIVVSSVPFTKNWWFGAQDTWRGYLGERQVILEAMWDVGLRGGVGVIVLSGDRHEFAATSFPPPPEGKEEIVGLGLTGVGAKHGTVLKPRDDPAIKTRRKKWPLSATVHEFSVSPLNMFYLPIRTYSEQTTSEDYVSDVCIKYLPDGNSKFGAVSISNPWSSDQSVLHYKMFVDGKETWSYTLTTPPNVRAGGHAKDATWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAB4</accession>
    <name>A0A9Q8PAB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Feruloyl esterase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763167.1">
        <property type="nucleotide sequence ID" value="XM_047906767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAB4"/>
    <dbReference type="GeneID" id="71987497"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07619"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051299">
        <property type="entry name" value="AB_hydrolase_lip/est"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040487281" evidence="3">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="90"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="19486" checksum="3E743DD2BDD89B40" modified="2023-09-13" version="1">MKFEIRFTSCLLFAATEAGPIPTKPSTQKPRTNVDQSLYDELIYYGKYAPTYPNAPCQIPPQGTVVQGFANADPTTEMTLFRADGDQELVMAFPGTAGLEDLLTDISATLVPYVTPGVNCSACQVHMGGLKAWNAIQPEAKRVLDQAIAAYPSYKFKIVGHRLGGMLTKLAYTSFAAQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAH2</accession>
    <name>A0A9Q8PAH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        </source>
    </evidence>
    <sequence length="3934" mass="392367" checksum="BF5975B8A860669D" modified="2023-09-13" version="1">MVLIDGTSTITLRSGASTTFGGKTISALDSGDGVAIGEPITSLFNPVQVQVTLGSGGNVITAIATNSSVILQVGSSTITIGNGAQTTIASQTVSVLPGGNGVVFDGSITSTFGASSTAPQAGAYPTPAIPSATTRTLSTGSAQQASVTISSLVPGGGASPSINDAVPIAAPQTGLAGPQSSSQSLDSSAMPTPAASSDDDLPCPIPGASYGYTVPSSGSQYVVQCNTTHGGSVYQILMTAEIGACLDACNDDIRCDAVGYDLGADLCYEYNALSAGNGYFSPTMHFAQLRSRAVVKDGFTSLEPVLISTYSTSGLMTSYPSNGAPILTPSLITSVRGGITTLSTYTTLVGSSTVARTQTIVNGGVTSISTTYATPNSGPSLAASILPASSPTPSSILSNAGSAAVPVTYGSPITTMTTVLGGQTLVSTYATLSGSSTAVETSTSVLGGQTLTITAYVTPTTTVGQVGSIGQSIVSQTSSGSSAMPGIVTVVADPSNTAPLTIGSQIAIPIASGAYVLPKGATLAPGGSAATIVGTTYTLAPSRSPAPGIATLTVPSGTSVPITIGDQVASPVASGAYVLPNGSTLSAGGPAATIDGVTYTLAPNAAQDQGIVTLTVSSGQSAPITVGSQLATPIASGAFVLPGGQTLSPGGSAFTSDGVAYTLAPSNPTLITLTPGSVQDSLIIVGTQIATPNASGAFVLPGGQTLSAGGPAITVDDVVYTLAPSAAAVASSVITLTAGQFPNAPITIGSQVITPASGAYVLPGGQTLTPGGSAVSFDGVVYTLPPVATPNPSAILTLTSDPRQSTLLAIGGQLATPLPSGAFVLPDGQTLFPGGPAVTVDGAVYTLAPATSRIQPGIATLTAGSLPISIGSQIVSPIGPGVDVLPGGQTLSPGGSAVALDGTTYTLAPAPTRAADAFTLTEAGGSAPLIVGGQTAAPIGPETYTLPNGQSLYVGGPAVTLNDATYTLASPTSQTPASVVTLSPGSGNAAVITFNGQAISPAASGQYVLPGGQTLSPGGSAVVLDGTTYTLPGFATSTTTRNIPVPAGLTTAIPGASQGSSFVLLLPGSTIGPGSSAVYSGTTYSLPTSGSGLYTNGQSVALPTTAPGSPITLSNGVVIDSATTFSGGVSSGEPLVILPGVTLLPGLAAVISSTAYSLPTSGNNVYIDGSPYAIPTVAPGAPITLPNSVEATPTVVPNVVLGTQTLLPGGAPLTVSGSTYSLSGSEVVVAGPSTTFNVALTGQAPSPSQASSTSINGEAASPGTPPALTIHGSTYTAQSTSAGQLASYLVNGQVLTPGGTIASTDTVGALETLSLDPAVGPQSIAQSTTSIPQASASVLSTATPILTVDGNTFTPISYTPGGLPTYVVNSQTLTPGGTIIATDSSGTLETLSLVPAGTAVVVIAQSTTITSQLIESAPTSAPALTGAPILADAPLITIGGTTYTAVSYTQGSRPTFLVNGQTLSPGGQISTPLSNGVTAVSLDPTGSFIAFVAPSTTLVSEIALAPTHGPEQVPLPVLTIKSNTYTAAPDSGVGVPTYVIQGQTLTPGGQISTSMQGGVNAISLDLSGYALKSIAETTTRMSQIASSALNSPATTSAPVLSIHGNTYTAMANTAGGLPTYMIEGQTLTPGGMISTALPGGVTAISLDPGGTAVAFVGQTSTSTSRLDVLSTSTGSPSTIPPVLTINGDTFTAVSYAQGGQPTYLVNGQTLTPGGQISTTLPGGISAISLESTSSALQFLGDNTVLTSQITTSTIAASGTDPSDMPTLTFNGDTYTATVFSDDAGVAYIIDSQTLMPGGAITLTGSNGVNTVQFDNADSSLIASNADSTTTLAAPGFNVVSQTDVSTQSMPAAPAQSIGFQPTAQPTGSQEQPTLSPVPSVPTPSATSSETAISLSAATSPYVTSSMSSRSRTRTTSSASGLVESQGPMTTYMSGGTTLATTIGGSTRIMSMSTRVMITTPMVVVTLTEDGSTSMSISTGSAYSITRDATVRTMVMGGVRTSYVTGGTTVVAPSTLIDPSSAPSATNVVAEQRIGMCPEYNGLLYSSEERSGSALVTCGNIYEGQVAANDTEVDAEGCDYSCVDMLDCMAFSYTENGCNLYSDVSGMRISEVPVFSALRLRTVQKAVDTTTLSAMPSTTATTSSGFMSSLASLFSSALGRSSTDLSTTTISSDSSPVSSNLPSDESPSTDQEASSGASGPATLTDMDIEPGQTTSAVTGTSNLAETITSTGEEPLVKTIHEGSTLTYESDGTTYTSVAQSEIVTFMPDSEVPISQQDTTSLAGAGPSSFIITYITGGSTLTYVSAGRTYTSVEGESVIASSGFGVAPTPQLPNMEATSNFGTTPLFTATFVTGGSTTTFSSGGQLYTSVDGGTIVETVADGPLLSDLPCQSGCLLPTTAVPGASASSATSGAQSIANDTLIAAEGSIGATDLPASTGSLADSSDLSGSTSDSTPSLAASHSTSSPPSISVPDLEVTMSLPSITPASITELGTISTVWGFQISYAWPSMVIVDGSITVTSTPSPTSGAGSSAPTSMTSSASRTVTTNAETELSSSSSADDAFSISATGPSSSLSASPSSMCQADTVGGQVLQNSDFCTDDMSGWSSGISSEVDPAGNTSAPGSTSSGRATVAVISRRAVISYARSTTEEPTSAWIGQPINATEGGVYNVTANLWITMPDDTSSVSFVMLQLGNTTVFSTGNITASQNYTISVNGAATSDMTAFRLISAYSGEQEGAVALDNVYVSFGSSNAPLPVNSDTHIAMTATSSPDTTNTALSDSTLAASSGEDLSPLSSYALGSGPVAADSGTQTAMTTPSSPDITASTLSGATFTASPSLELLPLSSMSASEPYLPSTSSPDMDTAAQPLTADLSAADLSLVSQSSSVISTQLPTSSTAATDLTLGVIASSDATQSPAEDSHLASLTDSATSGPTPVDITTSQASMGSAGPQASDLGAIVSSTSTSSLTTLAAALPTVSGSAVCPDNDGNTYDATDGSQYTVLCNQEYDTQRMMTVDSPTLDDCINQCAGQAQCMGTTYSIANGTCQVSSSMSSSNKQSNARVASVLRVRAPTVAQANVQTVLNPTFIDDTLSPWVAAGASDGSNFAAISNTASASFNFSQLANENVYNGGTPQATVWLRQWVNVTMGYSYFVSMNVNLTNGGDNTCQIGMMSGVQSLVSYSFPVGQSYYGSINGSGIITNEGTDYAMIYGSCSGNFDTTISVFNIVWNAWPPVSNVASTDNGVSSGSPINMEAPATLTSQLPQMDINTQLPAPVSSLDEVTSSATQPIVAIGDLPFFAPSTTTTISLNNAESTIEATTGGAVNGLSSIIEEISSSAVNPTSVPAADLTSSNTLITGSDAIPSSMISDATATVPNSNEAPNTNLVDSTPLSSISSKAPFPTASFEVAIQTSIAISTESTSPATPPGSGIGFGTPIVSSGINQQASPVATLINSQTSATTSILTDSVPFLSTSSTGIMALPSSSMLGLGSISSSATAVIANPSAVVPSSVASPAAPTSTLCPGYSNCTYTGRDGSTYLIVTAQVYESLTIPGIPAFLAVSLAVCIDFCTLQGTQCQGVSWRPDTQQCRLKANMIPTGNTTYPSVGAIRMSSSLAISAEVLVNGAFAAGMASWTTFTTGVTDLVVRLLNLVLGILGGGVGCIARLPGLGGLLNTLLSPLELVLVQTVNVAAGYSFFLQADLIIVNANFNTDASCWIYFRSENEVLWSGLYDRTSTASTIYGSGTLAAVATRFQAAAQCNGTTDLTVTFDNLSWKTYPRAIGISPINLQPMFALTNSAFNTALGAANGAWRIGAGTTSTIATTISGGLASMYWGAISATPTISTLLQDLAVGAQANQNFALTALVTVTIPPGLLGGLALCSAGIYLNESLWASGALAASQTFNVNARGTLKNDATQLSLWAQCSGSSPPRVTWDNVDLTLNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD27</accession>
    <name>A0A9Q8PD27_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764548.1">
        <property type="nucleotide sequence ID" value="XM_047909877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD27"/>
    <dbReference type="GeneID" id="71990607"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10729"/>
    <dbReference type="OrthoDB" id="5337308at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38999" checksum="EAAEE3726064BB67" modified="2023-09-13" version="1">MSQPDNTDTEPGLKAPETRSRTAQRVWLKVATATIVVAVISLLSICTIAPPLSYNTRSTTELVVQNASSVWQPIPAHEPFAFQKRDDWWDKKVKKGHWLPQAQWTDFAALEQNGWETEQWTLDKPGDNPFLKAIRALKIRTVLQIFGLSQRSTTPSAWTEMDHDHPASEASYQNLFSLADGVLVADFNYSPDYQIKLNELDVTAPALTQWSDIVFLDWQELHHQAGSSEEQKRKIQHFLRIKIRNEETVSTARAARNGGVRTGGQERPPGYPGWEWKIHEEAAEAIMGTANGAGTAYFLVQHKAYFGLKGLDSIRAFDCTEDEEDDFEMCLDFHVVDGPVVMRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDR9</accession>
    <name>A0A9Q8PDR9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764979.1">
        <property type="nucleotide sequence ID" value="XM_047910619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDR9"/>
    <dbReference type="GeneID" id="71991349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11471"/>
    <dbReference type="OMA" id="GEDMANA"/>
    <dbReference type="OrthoDB" id="3645966at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="29"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="29861" checksum="C1B88BDC7F5CB6FB" modified="2023-09-13" version="1">MEAGHCDQSDANGALRAGLIELHTTGALCDWTLKCGNATFRVHRTVMAANSDWFLKACSGGFKEGSSDTIGLQEDDNEDAEDLIRSMIHFCYHGRCEDDGIMKRLTHSVRMFAVAEKYLIEQLQDLAADRPSNHLLLRGRDYGEDMANAITEAYTNVSDPGNILRGTLVDYVATYSHLIFAEPNKSVEYAAVREAICQMPEAAADILRAVAGADKTKEKAAHDCRATREKSITMWVSQQQKELQDEMTLTCPNCGVTETKKKIEWMRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDY1</accession>
    <name>A0A9Q8PDY1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765051.1">
        <property type="nucleotide sequence ID" value="XM_047910738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDY1"/>
    <dbReference type="GeneID" id="71991468"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11590"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="36050" checksum="4927FA41EACD765B" modified="2023-09-13" version="1">MTRNEKPLPNVHGLHDGPVPRPKRKNPSDEKPKPKPPPRVIDGVIRTSVDETTGTSRGRTLQEHHDAKRSLSHPLAPDRRKREPSETTLHGPEPAAMGETSETRNQEISPVEPVKKHNPAELVSTPKADPNPKPKLRARKTATRNDDSFVDDDAEESKGGKKIIQATVEDDDEEEGEPIGPIPAKPVKTSSVKAIPTSESAKPATNRTTRSQSVHGNKDTGSEAANKATRTGKAPVSQQKAAAPAAGSSKRGASVVVRAPAEDQDEDQREEEENEEPKRKRARKSIDPPMITVEGGIDLHGRWAIRRYEVVASEERLELVRSRDRQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE18</accession>
    <name>A0A9Q8PE18_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </dbReference>
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            <begin position="54"/>
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        </location>
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        <location>
            <begin position="567"/>
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    </feature>
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        <location>
            <begin position="581"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="590" mass="66104" checksum="F447BEB26421A36E" modified="2023-09-13" version="1">MTAPKAKPAVTGVAYRNLDAALYQVRFLRYTSCDRNGLLRFELAVLSINVQPRYTALSYGWGDASTKERICINGQDALVPTNLVSALRNLGAKEGDLLWADAVCINQENKPEKADQVKLMGLIYEKAYRVVIWLGSEGEDTAHATALLGDFANHVNFRKLEEDGYAYHDQLAAEVTAPRFFSDPDFAHHWFAHILQKQKDPARALRGVNEIVMRPYWERVWVVQEAAKASRALVRCGRLRINLNAILAIVSCLPGIPHREQTLLETILKFRIQESNSAGDCSNRVSLYQALIDTRYSLATEPRDKVYSLLGLTSDGDDLLPTPSYVGTPEQAFATVSRAILRSRRATNLLLLSGWVPLNGKDIRPQVRAVDWADTKFRIPNWLTFSFGATTPTVPWQVVDLPDALQTNGCEIATINGLVSEDRHSISSTGWSIGSIDSSGTVTAGEIDGTPEEVVNELCLDLLQRFQQDQPLSEVVSHKQLTDAFARIIRDFNQGKPTTALRYGRLRYALETLAEVMLGQFPIWEWARRYNMARRYQATRQIIPDIQSGSRKARLLSTLCCCSAPKDLEMEDPDPNPRVPVSRESRKNLT</sequence>
</entry>
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    <accession>A0A9Q8PE27</accession>
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        <submittedName>
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        <name evidence="10" type="ORF">CLAFUR5_11628</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
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    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
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            <end position="64"/>
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            <end position="32"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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        <source>
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    </evidence>
    <sequence length="923" mass="102619" checksum="712FC61B7E0341CB" modified="2023-09-13" version="1">MKSATAGDAVPADVKQLDFAKASSNGISSHTPTRTTADAATATATTAARKPKQRSRRKNLTEEEDNAKRRCVSTACVACRKRKSKCDGNTPACAACSQVYGTDCIYDPNSDHRRKGVYKNALDSLKTRSSTLQTLIHAILNYAENEVPALIREIRTCESLDAVADRIMAKENGEDQDNDDEEPSPIYEEPEAPMPMFEKNLYGKMGDLRLDDGSVRYIGGTSNLIHLAQQEEVDYSNADDYLQQESPITSWTHVTNDPELVLHLLNMYFTWHYSFFTTLSKDLFYRDFSLGRPPPHTRRKTHYCTPLLVNAMLALGCHFTSHTGARDNPDDSSTAGDHFFREAKRLIMENDEHERPHLTTVQAMALMSVREAGCGREAKGWVYSGMSFRMACDMGLNLDSSQLTSNKYVSGDENEDDVRKITFWGCYLFDKCWSNYMGRLPQLPSSLVTATKYDVYPDEDSAQWAPYTDSGFTTAHAQPARTRAVALQIAKLCEISNDLMKYFYNPSDMEKTKGKAAELKKLSAIHTRLEAWRRDLPKEFEPKEGGLAAVLVMHMFFQLLFIHLFRPFLKYTQTTSPLPPNVSPRKLCTQAAAMISKLMRLYKRSHGLRQIPNIAVYITHSACTIHLLNLPEKNAKRDIVHGIKHLEEIAEGWLCARRTLAILSVLANKWKVELPEEASSVLARTDVKFGSYIGEVSSPAAQRRPSYPMSPSSMQPQPWQTYPSGQHAGHYFGTATIPKPTLPANHASAAAASHGANYKPPPQNASGMQPQQCPSATNKPAASLRWQSADSSHTRAGGSPSDMFGGVEQLIRDSSDWAYRDQAQLATGFENWDSINMDPNTWTSPVASSSAMHMPVTAGPVAGINISQPMHNRAMTMPPTSNGVYTSNTNAPAPDGTGMANWLNSMNAYNMSATAYNEDEWYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PED7</accession>
    <name>A0A9Q8PED7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11061</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
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        </subcellularLocation>
    </comment>
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    <dbReference type="OMA" id="RTGVWAW"/>
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    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371:SF1">
        <property type="entry name" value="BLR7753 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17594" checksum="DDA42E579CBA0764" modified="2023-09-13" version="1">MATVSFSIPILSIPLYYLLAILPHGYAISKASQGDLKKHDNRNPRGSTQLENIKKRLTPKEFAAFERGESCHRNHLENMPLYVATLFAGMLAENRVGEGELGLINFVVGWMVIRTLYTVNYLATEQSQGWTQVRSLLYFLGTGWSFLILGRAAFALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK2</accession>
    <name>A0A9Q8PEK2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11133</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the complex I NDUFS4 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765515.1">
        <property type="nucleotide sequence ID" value="XM_047910281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK2"/>
    <dbReference type="GeneID" id="71991011"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11133"/>
    <dbReference type="OMA" id="YDATIDH"/>
    <dbReference type="OrthoDB" id="3089at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.190:FF:000001">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 21 kDa subunit mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.190">
        <property type="entry name" value="atu1810 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006885">
        <property type="entry name" value="NADH_UbQ_FeS_4_mit-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038532">
        <property type="entry name" value="NDUFS4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219:SF8">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04800">
        <property type="entry name" value="NDUS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="25401" checksum="D705C545C89E803D" modified="2023-09-13" version="1">MASLRTAAVLRAAAARPALSLGAPALARFQSAQHDQHRITKDRETASTSEPPSSGATSNESSMIRQEGAAEGQARHNPDWSVAADYRTSNFSPVPMRVMDGSEPGVDMPAAVLSGAPIELQARTVRIYKPVKTATQSGDWPSHHWRMDWDPLSKGHRWENPLMGWQSSADFMQGTHLNFSTKDDAIRFANKQGYEYFVQEPNERRVIPKAYADQFMHSPKKLKQVRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEP4</accession>
    <name>A0A9Q8PEP4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765492.1">
        <property type="nucleotide sequence ID" value="XM_047910266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEP4"/>
    <dbReference type="GeneID" id="71990996"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11118"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="169" mass="18476" checksum="D7E9CB0959464EA6" modified="2023-09-13" version="1">MDPNFAKNCRELVIMGGYLDLNLLQTAGTVLLADLQSDINLMIDSEGAKMALTAEFPNITIVSNAANQIHEVSAPYTELISNYYGTEFPLWYETAAAVMLEPSIVKNSTKFYLDVDTSYASPGYGNIHAYQKALAPTAQSLQKVNFVIEIDGDALKQRVKEAVQASLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEX6</accession>
    <name>A0A9Q8PEX6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor PfmaH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11093</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765538.1">
        <property type="nucleotide sequence ID" value="XM_047910241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEX6"/>
    <dbReference type="GeneID" id="71990971"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11093"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="905" mass="99736" checksum="D76BFAE53A2163EA" modified="2023-09-13" version="1">MASLLDGNGSDPPATPSAAGNGANPFVCNVCQKTYGRIDHLARHFRSHTTEKPFKCLECGKTFARACGDLLKRHATLHTSTETSGKKRKIRASQACTQCATIKRCKTKGLECRVDSGSGHAVAQAEDHVSPTGSYGAHSDSRSYLADSRQSAGYVPTPPRSHGVTPMQQPSVPSVGQPEQMLEDPSLTDFLHNVLHPGQSAHTPNHPHPRTETTWNGNSVPRDLMDFSQDLSMDFNDLDTVLAGSWDGWLDPALMPSNMDKPTTTSDMSTPSIDDSINLGSQAYSRSAWKWVPNKERGDNDNALTSVLVDGHRNRTAPRPQQPALTQPLHRSDRDRIVALLLSGVLDIFLDDSLLTMEHSIDSWIHVPTFQPAHVIPELLTLVIAQGAVLSTSSHAQKFGYALQEKGRLSLPDMFERDHSMTRSLQALQAYATCLHVGTWSGNKRTMELAECAAMPPVTMIRRSGGFRRSRGTASGPSREDTGAALQQKWRNWIEAESFKRLAYHVFLYSVQVSSGFQTPPLSSYAEIRLELPAPQALWRARTAEEWRDQYFAHGLGAPLPTFVSRMSGPQTMGSARGKIDLELSLYLVLMTPPTKAQTSGQMQWAGTMLASSKREELRRLLDSFYVVIEQWNVFVPKEVHMFSQLLRMNLCVAFEDLQLLAGKEGEDEARRVYPSLKQWYRSPECREAMWHAGQVVRAARRPAGRSPNAAHSPTPDVPWLRDFNAVAPYHAELALWAYGLLSRAIYLEQNYSSVQHGHPTHHTPVLDYDGAPVRIDGDDEELSAIERHRFIAMNKGRAVISAIPPWSEEAKARVPGHGQSASSIIGVVAARGPAQEPAHGRPDTVPLDDPKIVMEVVMHALTPSSQPPMSTARQSTPVAGPQRPAMVENLIQLMRDLGEAASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF48</accession>
    <name>A0A9Q8PF48_PASFU</name>
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        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF48"/>
    <dbReference type="GeneID" id="71990957"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11079"/>
    <dbReference type="OMA" id="IREIRYE"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="20481" checksum="380451AEFDDECA67" modified="2023-09-13" version="1">MLTPTQPQTPLLSLPRELRDIIYTFALTSFPVNFNASSTRSSLPGLLLTNRQLHAETLSLYYKLLVVTIHPYHDGHFFRWLEKLPTERVALIQDMRMTLSKEGYDRGKLMRVKDRARRHYLLKEMRATLDQRGIKLGRGVLRMEVCVGDGVEDWVWTSEPLGLKWRGGRVREVVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFM7</accession>
    <name>A0A9Q8PFM7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkali-sensitive linkage protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765972.1">
        <property type="nucleotide sequence ID" value="XM_047908490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFM7"/>
    <dbReference type="GeneID" id="71989220"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09342"/>
    <dbReference type="OMA" id="WYDNFAG"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000207">
        <property type="entry name" value="Glycoside hydrolase family 128 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040326734" evidence="1">
        <location>
            <begin position="18"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="28"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="305" mass="33603" checksum="F8B7E56237A3BC8A" modified="2023-09-13" version="1">MRTSIVASILSLPLALAEQAVLTSTKRGLVYVETENKKDDHFWTSASDIRWYYNYESEPTSQLNNKLEFVPMLWGAGSDSNFYTTVKDLKDGGMNVSYVLAFDEPDGCGQVYGGSCVDAQTAAEMWKQQIEPLKDLGIKLGGPTVTSAPTGFTWLQNFFMQCAGGCSVDFLPVHYYGDFQGLASHIGQVNATYQNISTMWVTEYGLPNQDLEVAQDFYNQSSAFLNRVPYIQRYSYFGSFRSDVSNVGPNAAMLTQKGELTDIGAWYLGDAVAATGNIPKGDAVQLAKFAGWMMMVVAVSFYCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ4</accession>
    <name>A0A9Q8PFQ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin-like arabinogalactan protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765943.1">
        <property type="nucleotide sequence ID" value="XM_047908533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ4"/>
    <dbReference type="GeneID" id="71989263"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09385"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040277529" evidence="1">
        <location>
            <begin position="18"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="17"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="174"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="299" mass="30779" checksum="C66C356253E3F38B" modified="2023-09-13" version="1">MLLTSLASLGFVALTAAQDLISALHAQPDLSTLLGALQDVPEIAVVLAAASNITILAPTNDAFAQVPARSPLGTALANKEADAIAALLAYHVLSGTFMSTDFMEDPQYVSTLLVAYEVDGVSVTNVTGGQNVGLQLNGSDATILSGEKMSSVVTEADIQVGEIIVHKIDSLLTLPVKASAQASEAGLTGIVDALTQASLVETVDTTPDLTVFIPSNEAFAALGTGYEGLDTEALTDILTYHVIAGNVLFSPELSNTTVPSLQGTDLTVTVLGDAVFINEAQVIIPNIIIANGVAHVINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFX0</accession>
    <name>A0A9Q8PFX0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766119.1">
        <property type="nucleotide sequence ID" value="XM_047908806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFX0"/>
    <dbReference type="GeneID" id="71989536"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09658"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="237" mass="26786" checksum="BD6B1669D2319A6B" modified="2023-09-13" version="1">MSLFAGHGHDPNTPRSQGTDDLMQTRSLKPQEHAHTYSGKDKIITTRILISADRNTPCCTNIVARFTIRDHGRIASKRLGELHSFTINKTIEPTSGSDQNTWRQKMLSIPEGYKGNLRTHSSEKDAIQDREKIMMLLHDKEGSPSPHLSTEQRELLTAEQVHYIDKIRLEKQYVGTGLGFHFTGPVVLSPAPMDVKDSEYDEGMKKLIESYKRSGFEVWVNPDFQLRGPIAVMGRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFX8</accession>
    <name>A0A9Q8PFX8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766048.1">
        <property type="nucleotide sequence ID" value="XM_047908055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988785"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08907"/>
    <dbReference type="OMA" id="EKYDDSQ"/>
    <dbReference type="OrthoDB" id="5423371at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1985"/>
            <end position="2012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2077"/>
            <end position="2185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2268"/>
            <end position="2304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="801"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1617"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1876"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2082"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2115"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2161"/>
            <end position="2179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2304" mass="251907" checksum="A35A60DFA8EC335B" modified="2023-09-13" version="1">MSAREREVSRDREGRGHHHSHSFSESGSGRFSHVPMWDSSDPDRAPPPLPLAPGQGSPTTKANTSAGIAAAAKQIVERARESAPISAYTSNRSNDSQALPERSLVKGAHHKRLQSLQPGHVKDLRSYLDTNRSPERSPERPTSRGTFATPSRMNSSENLSPFTERPTTPTPAERDPMKDTPSLRPSTRQTTHRSILGENTPPSATMLALQTMQVPDPPLSDITNGPSTPSGTRVHTNYDFSSQLLNLTTIATNLQKEMAALSRRSKDNATDLIHLKDATNTRDEDIRKTLRDLANTVTGPGLLPPPPPLSTSTRRASDYSSPAYLDSKAFYSSPPSASKTFNLPRAASAHSFLDDRCGSPSPYSIEGAASVAMLEKIVREMVTKDGQERLQTSLSELLEKTRKENSNAAKKVEQLSEFIKEKTESQALVRSNGGPPRLEVNLGSPLATPKSSEKPTANEAPAKEEVLKLLQRIIDSVAHSGGTTSEVKGLVRDLRGEVLGMGRELGKKLDQIGETSLNNTLDRSIDAGSNGEHLEEVQRIVEEGLSELKHHLATVLKERAEQDDDTFKQLATTRAGPNSDEMLAVVRHALTEHHIQKREPETEEVGRLDRDGVLDAVKEGLKDFEPNIELQQFGLERDEILNVLKEGLEQHQSSRAEPADVNIDKGEILEVMQEALKDFQAPFPADQLAKYKEEILSGVQQSLEAFQPPPAAAVDQGAMQAAVFEAVKTGLAEHGPAAPREIEISRDDLFDAVKASLDGTTIPCGGLGEQVLSQLKELLDGMRVEFQQYSAANGRDTEQVLDAVKDGLESLRTQIEKYVDRAQDVTGKDEIIDSVKSGLEQLRGDVETMVGQDGDKSAMLDYIKAEFHELREQVRENGSSREVEESNAGQTTAVIIALQQGLDDLKSHMEARDDDVQTNEELNEAMKEEFEQLKGAILHAHATDKSELIETIQDSMGVLHSKFDGSELGTLSAGSSEELIQTMREEFATLKESIHAMVVDVDKDAVVQGVRQAIDDLRTQLSADQNDASAEAIGAIREELGAVRESLGGSVLSGGSSIHTVDTIDDLKNTLEEVKDAMAAKQTAGGMTDEQLEAFRGEFENLRNSIANSVVRSGSNEEILDAVRLGLDDLRSHLERKLDNPESVMSHQSQVLDTINEGLESLRTDIVKTLDKPLDMTVNYEILDTLKDGLADLRSEMDKLTSKNGQTVTPHGGEIVLADVGGVGATRDINLEDEAGTAAPEAAAAGGIKREDFEQVEILLAQLQIKIEALDHTVQDMPSHQQQAQVPEGIALREDLTCLELMLKDVQDNVITLAARDETPAPESAARKEDTDAIETLLRNMKAQIEEMELPDPASAASKDHLEEVQAAVRGGNETLEVLADKLDSQTACKADVAVVEVLASDIKGMLEEVKEKVTAASAEDDDKPERMTKSDLDVLGVLCTEIKTRVNEMTLPDPEELPSKSDIEQLQGLINDFRESHDKMKDSYETDIAVTAKAFDDRKKEHEDAVEQMGQVKEMIDEVKAELIDKLGFNDAGITTLGITLKAIEENVGNETVVSEVKEVMEKVKEEFEKAHDSLAAIKVDNAQSAETTLEKQSEHKEAIVTALGEKLDTLFDGLMSKYDDAQKAAEEKAKTMEENVTQQEEMLASTKAMADDLKLSIDTLGTTLTTFMGDLPAQVQEMSEQSKTVFDQAALTHSKLEEASDSLKGEHVATREEVAKVLAAVDVVQSDMAEHNPRFMVTLEEVRALINQHYEHSQKSSEAQNEHSQAVRDLQDALKAGFEDSKAQAQAHQEGLKSHHDELKTALPALLPRPVETPVPEKYDDTSVHEKLDKLMGHVEEASERSTQLERLDQIHEKVTATAAEVSAFVSAQNKQIADDHESKEKEAEEIALLLERRLERKDQLEADITVLNEEKESLANAVEALKAEKEALAAQKARLNADVSSMEMALHIRRDELHEMDNKAAALERRMLEGVMNQSRMLLLAKTSKPTSPKKQKPQGRDLRVPSNASAMSAATVTSSVPALKANHALAMKSRPGLMRNGPAPNTAERRIMSLNQINHNVPTGAHAFTAEKSSLTSLNGMKRSHSVKTHPTPRKFSWAGKRNTSLTSHNKENETLSEEDDDDISERAESRMGTEFGTEDGTERRHSRQSYLSRTDDGSMTYATGSYLNGETPGTNDGNRMSYAPSDMTYDTGSYLTGSYLTGSEIDRRTSLGSSANGVIGPVGGTESAISEDPEAELGAEQESMLLDAPPTNSEVERAVQEVLAEEKDSIKRHFAPPSDSGLGTDLPTANLSGGEESYFKGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGE3</accession>
    <name>A0A9Q8PGE3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766283.1">
        <property type="nucleotide sequence ID" value="XM_047908559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGE3"/>
    <dbReference type="GeneID" id="71989289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09411"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16693" checksum="3E7A6CC573D192F5" modified="2023-09-13" version="1">MSSPRGYTSCTRHQPTDLNIMPLTWLPSTSYELVSIICSTTILYSIFNLQIAFTPFIRLIQIPLTRFDQEPLAFVKEVQNIVCRRILLLTFNAFWLGHHHGSIMTCLLFAFTVFTGLGADRNADVWKFEVARLKVVRMAAAMQAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGT9</accession>
    <name>A0A9Q8PGT9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766584.1">
        <property type="nucleotide sequence ID" value="XM_047908004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGT9"/>
    <dbReference type="GeneID" id="71988734"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08856"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="482" mass="54090" checksum="C4AED60FDD6F4FCE" modified="2023-09-13" version="1">MPQPLKSKTGCLTCLARKKKCDEVRPKCGHCQRLGLACVRRETAPDLQSEQNISSTNLKAKGPPPRLAITNGYPPFRSDFERQVTLESSTVLRPLVSRMAGTWYLEETMFGRLCTQNRLVREAIVAFSAFGQDDRNEHSLKLSIENYQSCIMRLKQTRAFEHEDPAETVTAIVAIVFLGLLEALKLGCSVNAVAHFEMCRKLLATRLSQSATAGNVGLWNLYRMVAECIIYNLGALSVFQPNIVQAAGDWGTAFDRLFPGNDHYLSPFLGGFQGIYQVMFRVNVLLRQTEVDRTAGVLQLSTVETYDNLWQQLAVLEDNIPTMYQGNVLPKEIINLYQAKNRITIYALRIHLMKILRPLAGPEDVEIYLNLTQAIAILKEQDIREPGNPALRWPLSILLCASDADEDFDFVVSVMQQIELILDPANREKLKAAHNILRAYRTNASFAVQSGSLPTPLRQLDYLLEPTALEPAKPDGRVEEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHT3</accession>
    <name>A0A9Q8PHT3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trichothecene C-3 esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767064.1">
        <property type="nucleotide sequence ID" value="XM_047911663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHT3"/>
    <dbReference type="GeneID" id="71992393"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12515"/>
    <dbReference type="OMA" id="EGCTIQN"/>
    <dbReference type="OrthoDB" id="2373480at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040557038" evidence="2">
        <location>
            <begin position="17"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="44167" checksum="F43F2886B0B54266" modified="2023-09-13" version="1">MKATLILSALVAGALGHDRQAMMSRPSTGPNGTAAQILAPQQDPWYSAPANYESAAPGTILKIRPAAGNLTSVQSNSSAAYNILYRTTDSRYNATWAVTTLFVPANASSNDKLLSYQIAYDSADLDASPSYALYSGPYPDIVTALGQGWFVNVPDYEGPLASFTAGAISGHATLDSVRAVLASGLGLNTTSAKYAMWGYSGGALASEWAAELQVQYAPELNFAGAALGGLTPNISSVLLAVSGSLQAGLIPAGILGLASQYPELDQYLTDNLKTDGEFNATGFREATNYTVTEAIVAFASQDITQYFSNGAGTLFDPIPRSVINREGIMGYHGVPKMPVFAYKAIMDEVSPVNDTDILVDRYCQIGATIKYDRNTIGSHSTESGNGEARALSFLNSVLGGMYNATGCQIQNVTLNGTMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI67</accession>
    <name>A0A9Q8PI67_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,3-dimethylmalate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767274.1">
        <property type="nucleotide sequence ID" value="XM_047911146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI67"/>
    <dbReference type="GeneID" id="71991876"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11998"/>
    <dbReference type="OMA" id="HQNAAMI"/>
    <dbReference type="OrthoDB" id="1923844at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="33025" checksum="4EC9DC2C31BB0ACF" modified="2023-09-13" version="1">MSTNGQASKPAGVQRLREMLSDPSKTVVGPGVYDGITARLALAAGFECLYMTGAGTSMSRLGMADLGLATFNDMHQNAAMIASINPSVPVIADADTGYGGPINIARTVQAYARAGVAGLHIEDQVQEKRCGHLSGKLLVSREVYFNRLRAACRARDESRDDTLIIARTDARAGKDTEGNGGFDEAIERLKGAADIGVDALFFEAIQDLDEAKEVIKRLPNIPVLLNMVQGGRTPQVSNDEANKMGFRIVIWPCLGMEAVVPAFTKSLEALKTTGQPPSDQKMGPRALFETCGLKDLMAFDESVGGQAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF4</accession>
    <name>A0A9Q8PIF4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ GRASP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767600.1">
        <property type="nucleotide sequence ID" value="XM_047910939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIF4"/>
    <dbReference type="GeneID" id="71991669"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11791"/>
    <dbReference type="OMA" id="SSTQHIW"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="36"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="125"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="363" mass="37942" checksum="98CB7DDDCE3A437D" modified="2023-09-13" version="1">MANFFGAVNRFISRLDSDPNAAAQSGGNKPTSQNHYGFQVLRNTNPDITVEPWFDFIIGINGHNIDNPDPQLFMTEIKNCAGNVVSLGVYGAKGSQIREIYVNVPTDGGSLGLALQWSPLNVVDDVWHILDVMPNSPADVAGLLPYSDYVIGSPEGPLRGDAGIGEIVEAFLNRPLRLFVYNQEYDVTRMVTITPAKNWGGDGALGCTLGYGALHRIPAPLTEPAQAPGETLFEAGGGQGQDMPVYQAPTAGETYGAPPPPADFLVPANMPIAGQGATPPPPSGGPPKGGKTKKARAHHAPAAALDDYFAEGEQKSRELEGNSTPKPSGDGLPPPPPKAGAGPPKAASPAPPAEDDGEKTEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIL1</accession>
    <name>A0A9Q8PIL1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Broad-range acid phosphatase DET1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767453.1">
        <property type="nucleotide sequence ID" value="XM_047911043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIL1"/>
    <dbReference type="GeneID" id="71991773"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11895"/>
    <dbReference type="OMA" id="CNHANDQ"/>
    <dbReference type="OrthoDB" id="10261749at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="54503" checksum="AF0F3C36B18BE944" modified="2023-09-13" version="1">MVKPRLIILIRHAQSEGNKNREIHQMIPDHRVKLTEEGHKQAEDAGRRLRALLRPDDKLQIFTSPYRRTRETTEGILKTLTARDDPDDPSAAPSPFSRNKITVYEEPRLREQDFGNFQPCSSEMERMWAERADYGHFFYRIPDGESAADAYDRVSGFNESLWRQFGDADFPSVCVLVTHGLMSRVFLMKWYHWSVEYFEDLRNVNHCEFVVMRKDAETQKYILENNLRTWSELRRQRKEEQAKQDPQRRNTLSSFLTQSQDSPQIPPRKWGGCIDGCNHANDQYPRRTAQRKQQVQQELQLPPAAEAPEDNPNEAEDHPVAQVELTTKGGEDSGGVDGPSDEGSTTSSRPEFKRPFRPPAHSTLHPGRDGGSTTSGTTTPHEMSDNDGNQYFAPQAQKGTSLGNALRKAPRRKATPEDIERWAQESGMGKGKKADALGDEPDAWSDENRGSLDEKSASQDMDDLDRAEKEDKGLMGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJB8</accession>
    <name>A0A9Q8PJB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768065.1">
        <property type="nucleotide sequence ID" value="XM_047912433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJB8"/>
    <dbReference type="GeneID" id="71993163"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13285"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="26238" checksum="BC4A0F21632DBE73" modified="2023-09-13" version="1">MAPNSRIFLTRHAQAQHNVDLDYMGNPDSPLTALGKKQAASLAHQIPQLQQEADLIVSSPLKRTLQTTKLGWGPAVERLGGIKKVVTLPQAQEVNDYPCDTGSSKEILEADPEFAEFDFSSLTPDWTSKRGFWADDAGTVRKRAQWVRQWLRERPEANIVLVAHGDILRRITGNESGPSTYMWKNAEVREFPFRPDTVEKDEAYLHQEENIAAAGGYAPSSTEADIIQAGQEQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJE7</accession>
    <name>A0A9Q8PJE7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12987</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767887.1">
        <property type="nucleotide sequence ID" value="XM_047912135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJE7"/>
    <dbReference type="GeneID" id="71992865"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12987"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="295"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="518"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="577" mass="62383" checksum="E499CE7CAD0CA38C" modified="2023-09-13" version="1">MTETNPSSRSRPGSSGNALSPQQTARRSPTLKPQAITTNTISSTTTTPLPTPRKESSSLDPSPSVSKRSSFAENLNSRGYPSSPRAQRQHSFSGSALTELLMHPSNKTNGASDPKFKGRDWRKIQVDEIIDPAETRFVELDTSIEDTTKLLVRSGAPNVVLVRESTKTKTAMTTFDYSDLNAYLLLVLGLSQPDEQAAKLADRARSGEALPLKDVQDHLGARVEPAFLPQSATLTQAMEILGGGHHRIVINKEGTTEAVGVLTQLRLVRFFWDNHQNFAATETLYQMSLKELEVGAKDVIAINGDKPVADALRLMHAEGITSLPVLDQQRNVVGNISHVDVRLLTDTSAIPLLHGTCIHFISVILSERGMFDGKDSYPVFHVTPFSTLAHTVAKLCATRSHRMWIVDAPSPSTSVPPSPGPQHALPPFAMQSSSPSLSHASPQHSNPSPIHHTPIQTPARQGSGTEHIRDMTPGPPYTSINPGVTISAGQNPGAVMSGRLSGVVSLTDVLNLFARASGLHPTDPEETRRRRRQSSSSSVRPSIDGVRPSMESLKQSQDLSRSVDLGRSSSQHSSKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJT8</accession>
    <name>A0A9Q8PJT8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768207.1">
        <property type="nucleotide sequence ID" value="XM_047912476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJT8"/>
    <dbReference type="GeneID" id="71993206"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13328"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37128" checksum="907385B7D0D50ACC" modified="2023-09-13" version="1">MSNHTTPAPTSAPRPSYFDTIASTIASSSESSTAHFEQTWSSHLGNSYLRATPRNTGKGPGLLDLPPELRLMIYGSMHLGPHLTATGEGAKEEGAEAIDIAALLNWKKLPASEMTARNPWNWILTHPLFFTEALDSITQRHAVLLRSLEGVTLALPYLTHVKTLILDFAYVHAIETSDALDNLRNLPNLEILRINTTPSTLPFCRSPAPLSGFSALHTLTLHNVSDEAEERADQAAHQLRMTKLEAQLAAANENLQAARLATAGVSLNPWQKLQQMQLQLDRLDIDAEIVKLRLAGVEGVWGSGAVRDSRIEARRGRRRGLRRREIGLRVDLGLGGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKB3</accession>
    <name>A0A9Q8PKB3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768462.1">
        <property type="nucleotide sequence ID" value="XM_047912443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKB3"/>
    <dbReference type="GeneID" id="71993173"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13295"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="30902" checksum="505D5FA0BF17319C" modified="2023-09-13" version="1">MAHHRNSILAAVDLLHEVSKSTHTDIIAQPHQRSRMPAGFVSHDPPAGLLTLPQELRDRILDFLPLVSPTGLVFLPDVEDTPSNPSRLYSRHNPDGFEAAWHYRGLTEVCRTLYHDVKPHFWSKNKFVVHFEKNGLGQWLKVPDSCLYHVRCLTIKAGPWDTHVEKEQNSPRQCTIDMTVKPLERTAPKHEWDIWLLAWQPPADLDPEDIIDDRKWTKGQRTWARDVQIKCASISKSVGTLTQGAGEGRFSSTINQEIVNGFALLRQFCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKQ0</accession>
    <name>A0A9Q8PKQ0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768604.1">
        <property type="nucleotide sequence ID" value="XM_047912812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKQ0"/>
    <dbReference type="GeneID" id="71993542"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13664"/>
    <dbReference type="OrthoDB" id="48036at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052436">
        <property type="entry name" value="LTO1_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532">
        <property type="entry name" value="GEO13458P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532:SF1">
        <property type="entry name" value="ORAL CANCER OVEREXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="21239" checksum="E07CCD81069B1F75" modified="2023-09-13" version="1">MQADDGHEELFGHVLHLEDQYYREGYHLGVADGSRSGRIEGRTFGLEKGFEKFVEMGKLHGKAVLWEARLPATISSDTPATANGTTNLPPLQAPSGNARLRKHVERLAALSDPNDLSTENNEDAVSDFDDRLKDAKAKATLISRMAGEHDSTTEASAPGQSGRETALRVRRTGGSDVANTPARPTGEMEDFVGLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKR4</accession>
    <name>A0A9Q8PKR4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768666.1">
        <property type="nucleotide sequence ID" value="XM_047912777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKR4"/>
    <dbReference type="GeneID" id="71993507"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13629"/>
    <dbReference type="OrthoDB" id="3650839at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="1">
        <location>
            <begin position="102"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="371" mass="41253" checksum="A6ED59984FF414D1" modified="2023-09-13" version="1">MPERLHPRGWNKWRQQWFWRDSKERLRAEYDGDFKAYMAAFQPEIQPACPLRDGMKLFQKLEKSGQHATVATNFASASTLVSRLIECLSSGMTTNTSEADFIFVCVDFEGDTKQGVNECGISTLDTRDLLNPTDSVPQNALKTVKYRLVKQNDRKFFHGHTTMLHPDALRSTILDAFNIEDDLSPGTKRKIILTGQGVDGEIATFRGLLGIAMEDLPIDGIIDTHALCGETIGQAGKLKHILATLGVPHESTLLHCAGNDAHFTLQAVAALLAIKLREELPPKQKGVSHTRTPCASVPATSAEMEMQHAGLRRTMPPALYIDSSPATNAELRRLEDIAKKVVLRPARTAREEQETWDNYLEEGGTFMALWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL03</accession>
    <name>A0A9Q8PL03_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MYG1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768727.1">
        <property type="nucleotide sequence ID" value="XM_047913086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL03"/>
    <dbReference type="GeneID" id="71993816"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13938"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="425" mass="47088" checksum="E6D7FFC5AC750B91" modified="2023-09-13" version="1">MNRLRFASNSLFHRRVPTSIRCYCPAPITSAKPAKTPDDLFQRLVASHPQLYRPLLMSEPASKRVKMSNGTAAPVIGTHNGHFHADEALAVYLLRLLPEYQNASLTRTRDAEVLNSCDIVVDVGGVHDHAVKRYDHHQREFNATFPGKHTKLSSAGLVWMHYGKQIISAVTALPVEDADNELLYQEIYEDFVEAFDGNDNGISSYDPQELRKAGIQKKFNDGGFTIASVVSRYNRAPVSQLADGKPAGNGAPPAQGKPEKTQDEEDNRFLRASQFVGEQFSLKLTDMFTSWLPARAVVAKAFNLRHAVDPSGSIIVIPYKAEGVPWSDHLYSLEEEHKVQGNVLYALFAENGEPDSKWRIRAVSLELGSFENRKGLPEAWRGVRDEELSKLSGIPGCIFVHAAGFIGGNKTFEGALEMAKKAVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLU0</accession>
    <name>A0A9Q8PLU0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Survival motor neuron-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769163.1">
        <property type="nucleotide sequence ID" value="XM_047912891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLU0"/>
    <dbReference type="GeneID" id="71993621"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13743"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040424">
        <property type="entry name" value="Smn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267:SF1">
        <property type="entry name" value="SURVIVAL MOTOR NEURON PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267">
        <property type="entry name" value="SURVIVAL MOTOR NEURON-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SMN_YG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="6">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="169" mass="18512" checksum="03EAF9A72AE89851" modified="2023-09-13" version="1">MDINNSNHIIPFSDLHHVSLFDMAAQEAAELTHDELWDDSALVNSWDEAFAEYKKYHSLAAKGEKVQVVAVEKENETSSETPNGITKQPQSTAPVNFVHTTKSTATTAPVPATTAGPIVPPGLASLPQNIITPGQDENLKNIMMSWYYAGYYTGLYEGQQKAWAAMQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLX6</accession>
    <name>A0A9Q8PLX6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769317.1">
        <property type="nucleotide sequence ID" value="XM_047913627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLX6"/>
    <dbReference type="GeneID" id="71994357"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14479"/>
    <dbReference type="OrthoDB" id="3646734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21746" checksum="622EE63B75BCAFBA" modified="2023-09-13" version="1">MLTLPQITKPQSLACLAVFDTAELAEAIFLELPMRGLLVNVQRTCKQWKAVLDGSRKLQQAMFFEPIADQALHPDTPHELAETRPAAHPLVIGPYLNPRADKYKYSQLDVLWRLNASWRRQLVSQPPIARADVLNSRHGDYAAGVSKVVKAGAVGVTWGDMFVAGFTRPDEAIITGLTHWRLFSLAEGPTYTDIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM28</accession>
    <name>A0A9Q8PM28_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Siderophore transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769286.1">
        <property type="nucleotide sequence ID" value="XM_047913559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM28"/>
    <dbReference type="GeneID" id="71994289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14411"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF58">
        <property type="entry name" value="LOW AFFINITY HEME TRANSPORTER STR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="642" mass="69807" checksum="B98C97CA6CD28095" modified="2023-09-13" version="1">MADHKIQGDLGEHGLNDSHRPLTITQDGKQSPTSSITAPNTPDNDIEDGREVINPHGSVTKVEAFNRVLRTSGKGKLLLYTLAVSIGLTMFAYSMDQGTTYLFNAIAASAFRRHSSLGAINTAGQLVRSISKPFLGKLADITSRPTTYVVVLIFYAVGFAVAASGQSIAAYTIGTCFTAFGKSGIDLLGDIIVADMTSLQWRGFFVSLLGLPFIVTVFIDGFISDAFLPDKWRWGLGMFAIMVPVLLIPPIITLYAMQHKAKKLNMVSMGGSKLARTGQVNNINKKSYLQLAWQGIIDIDLLGLLLLGFGFALILLSLNLYTTAKGGFSNPSIIAMLAIDLILLITFLLFEIYIAPKPCCSRRILINKAFISALGIDIFGLLASGIHSLYFPSYILVAKDWNLYNTNLFTNTVTLVLVVLGPIAGLILAKTHRFKFLMLLGAILQLIGYGIQLNSPLATTNTAQLVISQILSGCGSFTVVGARVGSQASVPHEDLASIIAQLSLWSSLASSIGFTIAGVVWGDRMLPWMREECPPEVSSAELRKIYGSIKTLRDYPWMSTIRECGVRAYQRTNGVLFIVAVAPAAVALVFCFLMPDYYLGKQHNLVSNTRPDGEAVEDVHSEEDRGQLRPRSALGRFWNMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM84</accession>
    <name>A0A9Q8PM84_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_14112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO25021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM84"/>
    <dbReference type="GeneID" id="71993990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14112"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
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        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF647">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="27986" checksum="A5E4C13205FC16CA" modified="2023-09-13" version="1">MRVRFPEQGAAAEYTTAIAPELSIRPSNITAVQAASVPVSALTAWQGLHEHASFDLRSFKLDKAAGETSMRILINGGSTTVGIWYMRLLYTMQFPRPITITATCSNANMHRVRDFGADNIIDYTKTDNFSAHGPYHIIFDCVGRETLDKCWRALAPNGSLFTIVPTLETTNYVSGPLTVPDEVKDRGIRGMFFLMRPNAEQLGKITKLIEEGRVEKPVVDSVHDFEAYEAAFNRVRSGRAVGKVILKVCEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URF9</accession>
    <name>A0A9Q8URF9_PASFU</name>
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        </recommendedName>
    </protein>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    <dbReference type="GeneID" id="71990138"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20902" checksum="98C8B85883AE2305" modified="2023-09-13" version="1">MHRNAQTTRKSDIENCCLADRHRLDVSAPPAGTTNVACAGTVTAGHVHAFQRSPTNHDDDDFISADRTDVPLKPYAQNEELKIEWVSTMTKDGFTSPNCWYRALKEDYHLDTEKGLDGKLDKPYLFIASDGDAVCRTDAIERAKGSGLVPDHEVHEVHSGHWAPFEQQDQISKIVLEWLKKKGFSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US36</accession>
    <name>A0A9Q8US36_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764717.1">
        <property type="nucleotide sequence ID" value="XM_047909224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US36"/>
    <dbReference type="GeneID" id="71989954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10076"/>
    <dbReference type="OMA" id="FPINGTY"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040453270" evidence="2">
        <location>
            <begin position="17"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="292" mass="29457" checksum="DDDFA9FCE197E376" modified="2023-09-13" version="1">MKTFAALSGFAAIAVAAPFPTGYGLPAPSGAPYPAHGTGLPPLPSAGIPHFPINGTYGPHPTGLPFPPDGTGLPLPSGSFPDFPPNSTFGPHPTGGYHHYPIPYGTAPPQPQATGVCKREAQLGEGLSLHGAAASTSGLSGNSGLGSGSQPSVSLSTGGIAQPTGLGTGTGGFLSLSLPTGGVAAPTGHGHHDYEGHAAPTGLPGHGAPSVPAPFPTSVTGGVAQPTGLSEVNGQRRYSGKISAPWRVRKMLKRTRMKDFMCQRQDLASTNFGDAKQSNPMQSFEHPIPSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU91</accession>
    <name>A0A9Q8UU91_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766908.1">
        <property type="nucleotide sequence ID" value="XM_047911559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU91"/>
    <dbReference type="GeneID" id="71992289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12411"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="484"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="684"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="724"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="821" mass="90996" checksum="A36FE53427BFADDB" modified="2023-09-13" version="1">MSLNLETEDMGQHTTMDDTPSASAFSNPAWFLPIPDNDMTDAHIPDSSGPLKRSGCDVEAATKRVKRDKQTVELGATPGIRDTRNPEDSELLNSVRGLLDEGLGLSQAEKELLAHDLDMGKFDAKAEQKVAEIAQQQRSALREVRRRESASSRAYRRHLAEKELENAKLKQELAALEPPFSRDQMRRATEAKEAAEKCFVQMQGVIDRLKRQVQEERAARRRDHEEAYREVNRYEARLDALALVVKAVIEARKAFSRFGLAEPLTWRNLVAESQLPQPLHNHGPTFDRHCLACVSGSMQPGHHGNGQTSQQESPEEDVRSVEEPSTVREHRATSMGFPEIESVDTIDSSSYETDSSSSRESMFGAPTVLERPQMVSTGIPKTTSQEPTRRSPGTEPKPPTVQKRKILLRTLDDYIKTDARLIQPLSTAKLGRIASRSGFREKFRLGRVIKFMRDNKRIALSQDELKELYGQCTREERLHLTHTSGAGSSAASSSAAEESEKDGGEAEVLKESFDPPCHDESGRSTENQHGSTSTVTQERDNTLMGCTGSAPRPTDPVTAPLFGAFGSARQASSFGKPSAPLSASTETNKASTPSDKAADDIQEDKGDEPAFTPPTQPRAMRGTQQGSQHVGKGKGKGPADPTYHEKIEETNRTHRVPLAHRDPNIGKGPAAASSKHRGLDIKGAAAAEAAPEAESDPYAAERERNRHKRETRKAAHNKGPQPGRRGDRPNNRRRRLTMEGRWDSRHDELQRSAPHPRPRSTYCGNERHVRDLSARADARAPLALVRTDVHKYRTWGRNNSRVFSGQRKCRGEGRNDRESAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUA0</accession>
    <name>A0A9Q8UUA0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_12287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767041.1">
        <property type="nucleotide sequence ID" value="XM_047911435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUA0"/>
    <dbReference type="GeneID" id="71992165"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12287"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000004">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11 15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="27"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="12">
        <location>
            <begin position="251"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="13">
        <location>
            <begin position="541"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO22675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="881" mass="99443" checksum="341E7433B5EC6BD4" modified="2023-09-13" version="1">MCRKDADTADANMDISKGRVVLPKNVKPLHYNVTLEPNFKTFKYDGKVEIELDVVEDTKAISLNSLEIDIKHTEIKAGGSTITSSPKLTHDEDTQTTHVEFTETIPAGTKATLIQKFEGTLNDNMAGFYRSSYKGDNGEDAWIATTQMEPTDCRRAFPCFDEPALKATFTVTLIADDKMTCLSNMDVASEKEVESAFGGKRKAVTFNKTPLMSTYLLAFIVGELKVREDNSFRIPVRVFCTPDKDIAHGKFSVELAARTLEFYEKEFASDFPLPKMDMVAIPDFSAGAMENWGLVTYRVVDLLLDDRNVSASTKQRVAEVVQHELAHQWFGNLVTMDFWDGLWLNEGFATWMSWYSCNIFYPEWKVWEGYVTDNLQSALGLDSLRSSHPIEVPVKRADEINQIFDAISYSKGSCVLRMISKYLGEDVFMEGIRRYLKKHAYGNTTTGDLWAALSDASGKDVERVADIWTKNVGFPVVTVTEDPKNNKIHVKQNRFLRTADVKPEEDQTLFPVFLGLRTKDGVKEDLTLNKREADFDAPLDFFKLNADHSGIYRTSYSQERLQKLGENAKAGLLSVEDRAGMIADAGALSAAGYQKTDGVLSLLQGFDTETSFVVWDELTARIGAIRSAWIFEDDKAKDALKKFHRDLVAPQSHKLGWQFSDKDGHIEQQFKALLFGNAASAGDEKTKAAAFDMFEKFTAGDRQAIHPNLRGSVYAVVLQYGGVKEYDALVHEYETGKNSDERNAALRSLGRARDPELIKRTLAYSLSKHVKEQDIYLPLAGLRAHKEGIEAFWAWMKENWELLRQKMPPSFTLLGSVVSMATSSFTKEKQLKDVEQFFDAHSTKGFDRNLAQSYDAIRAKIGWINRDSKIVEQWLKDNKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVH0</accession>
    <name>A0A9Q8UVH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768314.1">
        <property type="nucleotide sequence ID" value="XM_047911877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVH0"/>
    <dbReference type="GeneID" id="71992607"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12729"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="16644" checksum="70FC58E860E93BB0" modified="2023-09-13" version="1">MDDIKVATSLLDLPAEIWSKIGKLAVDVSKPITSGDFFTHPPRYFQPPITRTCRVLREELLPYFFSTRTVIWFPTYSVVKLGNWLRALDPEMRRAISGICTEALPRSVQLLEYQLEEAWRVSLSLVLLEEAEGPWRKYVVRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVH8</accession>
    <name>A0A9Q8UVH8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </evidence>
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    </evidence>
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</entry>
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    </evidence>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71981626"/>
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            <begin position="310"/>
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        </location>
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        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
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        </location>
    </feature>
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            <begin position="39"/>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57083" checksum="E00925BE6ADFF8D7" modified="2023-09-13" version="1">MADEDKEKAEKLAAAKKRFEQLKKEQAKKGKKGSKKKADKADEAKAEEAVDDANEEAASANAKADENDNDGEVETEAAHDVSEPSQSKQRSESFRQATSQTARVEELEKENKALKEQHEQESTRLTKAEDELDSLREGNSKLAELRSKAKEADSLKTELAAVQRQLSQAQQAAKGPARRQSGATPDISEQLASKTSTIESLELDMSNLRNKITTLETTISERDASIKDLGDRVEASDAATDSAKKELDALKVSIAFPSDETKAANEDPEALTKRITVLESDLRSANSNLEAAAQRASSLEQKIEALTKLHKETTAASQGKDKELNDLRSQLKHRSRPSHVHDTSDFDLAEEETETGALAARVRALEAENFDLRRGVWRDQRAALQPGMEDRDPGSVNYEDVDLNGPYSPGGGHRGGLPRQTSTFQDVITSGISAFTGRARETVAPRDRAESMGLMSDDDGFDEEAFRLAQEEEAKRRIERIKEVKRGLDQWKGWRVDTADMRRNGLGPGRDVGPVFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6H0</accession>
    <name>A0A9Q8L6H0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Required for respiratory growth protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for respiratory activity and maintenance and expression of the mitochondrial genome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRG9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756117.1">
        <property type="nucleotide sequence ID" value="XM_047900234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6H0"/>
    <dbReference type="GeneID" id="71980964"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01086"/>
    <dbReference type="OMA" id="WEEMSAT"/>
    <dbReference type="OrthoDB" id="5578174at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010487">
        <property type="entry name" value="NGRN/Rrg9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475:SF3">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06413">
        <property type="entry name" value="Neugrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="473" mass="52567" checksum="DBA8A3859020391D" modified="2023-09-13" version="1">MPESPQMFPGHLDGLHVDFCTQQAQLAASNPTTTMTSTLHRCSCSTRALETLVKELAGIDLRRHRAQRFFQHSRALSTRPPTRHVATVAHTHADHGFVSFQPGSSSSSQSAGGSARSSQATTAGTQGDPEASQRKDEGDREWHAEIETMQPGRREETEVISQVGTIDSVRLPDPGLELACNDVANPVAPILHLPAISQRFTQGDAQPMSAMKPALGSKTTSRKLRKARRIEAGTYKPAADSRLTALDKIEMLEGPSMKQKAEQPMTHELETKSAAQNQTIDGKRRSKATVGAKGVTKMKENNTGSSKHTAPSRTPPKDKTVKKETWQIQKAALDRKFAGQGWQPRKRLSPDTLEGIRALHASDPASYSTATLAEHFQITPEAIRRVLRSKWRPKPEEIEDRMKRWENRGLRKWEEMSATGVKPPKRWRDMGVQNPLLKKKLQKKERSNEAGWNRAEQLADRLPFGGSFAERLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6R8</accession>
    <name>A0A9Q8L6R8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major royal jelly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major royal jelly protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756297.1">
        <property type="nucleotide sequence ID" value="XM_047901082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6R8"/>
    <dbReference type="GeneID" id="71981812"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01934"/>
    <dbReference type="OMA" id="CFINVQN"/>
    <dbReference type="OrthoDB" id="7776143at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017996">
        <property type="entry name" value="MRJP/yellow-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10009:SF17">
        <property type="entry name" value="MAJOR ROYAL JELLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10009">
        <property type="entry name" value="PROTEIN YELLOW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03022">
        <property type="entry name" value="MRJP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43667" checksum="07EF413C3D29BF7A" modified="2023-09-13" version="1">MLSHYPLLSFVPAALAYFDTSGFRPFGPGYNHGAYPEDYGVTGPPLDAVHDSQNAPTGLAVDDDHRVYLTYPRNSGQTPNNVVICTTFNDEEPWPNAAFQNCTEDQDPSTCFVNVQNIVLDSIGQLWVVDSGIPYTAEPGSDALYGGAKIMSFNQSGQHIRTYILSQDVLAHGMNANDVRINNTLGTNGYAFITDESTTIPQFWPADEGYVGSYDGELVYCWNGTQRNFCTTGADGIALASGNFYWGVLASRRFYYVPQSIVIDPNATDADVLAAVQDPGQCASEQAGFTADDLGRVYIFASEQNAIYYVDTQQSEVTETVNDTPPGGSGLVPAENYVVKTLVRNGMIQHADSGAIKDGWLYFGTNQLNCHRVGSTITPMHVAVPFVRSGYGLMDEGLQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7A2</accession>
    <name>A0A9Q8L7A2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756405.1">
        <property type="nucleotide sequence ID" value="XM_047900619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7A2"/>
    <dbReference type="GeneID" id="71981349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01471"/>
    <dbReference type="OMA" id="DILYRTW"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="22287" checksum="676BBA85911BB555" modified="2023-09-13" version="1">MTVGAEDAEDGYILKLDRGLGVRRYRLSDAESMAHHANNKNVAKFMRDRFPSPYTLEAGNFWIELCNSQKSMLQAGEWSSETGASGPLTALNYAITVNDETVGSIGLEPGHDVYIRSAELGYWIGEEHWGKGVMSTIVPAFVQWTWKTFGILVRLNGEVGELNKGSAALLGKAGFVVEGRRENAVFKNGKLESVIMFGALRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7F3</accession>
    <name>A0A9Q8L7F3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutaredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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        </lineage>
    </organism>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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        <text evidence="1">Belongs to the glutaredoxin family.</text>
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    </dbReference>
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        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558:SF1">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13599" checksum="EA16F77FF94C5AC1" modified="2023-09-13" version="1">MRRHIVFNMHSTLRLMQHSLRLTLFTHDRCSLCDSVKGVMSKVWDRRHFEYKEVDILAPENKQWMSLYELEIPVVHVDRTAMLASSNGETTAAARKLKHRFAAGELEKVMDEVERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7I6</accession>
    <name>A0A9Q8L7I6_PASFU</name>
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        </submittedName>
    </protein>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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            <begin position="1"/>
            <end position="20"/>
        </location>
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            <begin position="82"/>
            <end position="166"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="274" mass="27227" checksum="9C623021694E382D" modified="2023-09-13" version="1">MTLFQALLLATSLGWTIVEATPPANAAAGLPPAIELPDSPAYRNNITSIARTGTGLPPAPIVRTEKSQASLNVPCQTCPTYNSPRVESTQASLAGPGKPTPSDPHPSGPKITEPSATKQSQVNPETPTASPSSPPPEETTPPAASTVPRIPIPERTRTTLDAPSAPYTIGPSYTIIPGSSAIVVSGTTYSAAATGTEVYVNGQVVSTSTVTIGGTAGAVGTATSSGGGEDAGGIATESGSEAALQTGGSVEGKGRAVEVVGFAAGVVMLVVAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7L9</accession>
    <name>A0A9Q8L7L9_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">DUF7729 domain-containing protein</fullName>
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        <name evidence="3" type="ORF">CLAFUR5_01187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Fulvia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO12266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7L9"/>
    <dbReference type="GeneID" id="71981065"/>
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    <dbReference type="OrthoDB" id="2564812at2759"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
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        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="149"/>
            <end position="353"/>
        </location>
    </feature>
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        <location>
            <begin position="98"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="41560" checksum="F76093575FC50EF2" modified="2023-09-13" version="1">MTTAISSCSSTRTARAAVQPWLCYRQRWNEPTSSLCHTRRPPPARTISKQIDGSISRASNLALVFLLCLLAFCQGAKADVLYGFGDISPPELLFDRSEPPPLPRMLLEPRQDDSLSSLPSTTTRPTGSSTPTTPGSGIQTASETASFDLPRPFDTSIGNNFTTTTCPTFFQNFLSNQTLRDCLPFSLLLQTSNSFFTASRSPLRLAQTLNATCSVDFNTCSTLMSQYAQQIQQNSHCGADLEMQNPMVTQAYNGFVSYPTLYHAGCLTDTDGNYCFSNAVTNTSSPSSSYIYYLPLGVKLPGGARPACNTCLQNTMAIFAETAGNASQPLSQDYGTAAEQVQMICGPQFVDSSIMTSAATTSLPPHTPSMGLAGVAISLALLWNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7V8</accession>
    <name>A0A9Q8L7V8_PASFU</name>
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        <recommendedName>
            <fullName evidence="4">Cell wall proline rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7V8"/>
    <dbReference type="GeneID" id="71982104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02226"/>
    <dbReference type="OMA" id="FNTPDMR"/>
    <dbReference type="OrthoDB" id="5406427at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
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        <location>
            <begin position="161"/>
            <end position="189"/>
        </location>
    </feature>
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        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
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        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
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        <location>
            <begin position="738"/>
            <end position="765"/>
        </location>
    </feature>
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        <location>
            <begin position="779"/>
            <end position="791"/>
        </location>
    </feature>
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        <location>
            <begin position="866"/>
            <end position="882"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="889" mass="96123" checksum="7EAF6FCC2A8C3A69" modified="2023-09-13" version="1">MTEIMLPGHSNYTDNLRAMSSNIPLAAAGPKIEMLPNPDFSFPRIPPADSMPQLSRNSRAHRRPMSVHMDSLKPQPSETSHRRGASMLPSFTFNASDTTGLTADQAESTQTSPARSAHKRNTSELVGGHGVGMSGAISASPTKSAPLAVPGRPSGHKSRASRVTLSSSDWSAVMTTAETQPRLSSSLPNTPLDGPPGSTSASNDPFGPPLDSSPARPPSRPRVEFSENVEYIPRPLSTISSETESSMSTVRGHSVNNSISSVLSLSSPSPPSSRARTPSLSTTLENEPRSQTKSPIGLSRRVEREGQWLKHGNSHENLRRPISQPSAMPNKLTFATEAHVGKGRGVHGKHKSLSYALGFDRRRSEPAMGMHADEPSRFSTISLQDPVPHTAVDQSGHYNTEQRSSSRRLKDWAVSKISRRGKESGRRHFEYLAPSYQYPHADASPVIEPESAEAETDLDAVFSMDADPVSAHSQRVEIEPPVFASHTYSNLPESDDSGGMLDLDAALGPFKTPPFGAHKSRRELHSSRGARDFFGPGGHYQPTPSHRRAESAPMLTPWDQTRIGTPPQPGMADVFEEEEEEEGEPARPGSTSSTQDEESRMGVQIVDSDVSANSSTPSLSLDDGLRIRHAEWESERPATAFSHMSSSLGMPVLNRRASSVIEDTIIEESSPVEPAIVEFHEEPRAHSLTKSSDSSETPTIVGGQPGMLTLPDGQQSLTTPESYQTSAFSTPDFTRRQTSFDTSRVGTSASSMTGNRTMSSCTTGEPTPDVRISVDDIPSLTSSRSTMLSTSHANSSRRDISGLRTPSVASGTLDSTAHHDRWRKRASIASLSQLVGSPFGPRPGTGVSERPQTAATDLSSKEPKKKEHRLKKLMFWKSKHRQASTSTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L885</accession>
    <name>A0A9Q8L885_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Chromatin modification-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_00151</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
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        <property type="component" value="Chromosome 1"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:protein kinase activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
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        <ligand>
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        <ligand>
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</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8V0</accession>
    <name>A0A9Q8L8V0_PASFU</name>
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        <submittedName>
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        </submittedName>
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    </gene>
    <organism evidence="5 6">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757359.1">
        <property type="nucleotide sequence ID" value="XM_047900748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8V0"/>
    <dbReference type="GeneID" id="71981478"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01600"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF128">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxiredoxin C-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="25522" checksum="0B6A3AE5436AF93F" modified="2023-09-13" version="1">MFGSAKVGKCSLRSEEHCVRGRQIHRSLTTVMISRDYGVLLEEEGVAQRAAFIIDPKGRVRNITVNDADIGRSVDESLRVPEALAFKDEIGEVCPVDWKKGDKGLDHSADTTVEGPVEVPRCSWGSATPTVRSVSEWARPKLQRAWPATSKASIACPIQLAHPASSDETGDRGISSVRSGRHSPLVIPGKKIEGESTFQDQLDKALSAQKSISAAIENMQAAMRTQPIKVANWPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9C8</accession>
    <name>A0A9Q8L9C8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756959.1">
        <property type="nucleotide sequence ID" value="XM_047900220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9C8"/>
    <dbReference type="GeneID" id="71980950"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01072"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF120">
        <property type="entry name" value="HIGH-AFFINITY COPPER TRANSPORTER CTRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="21032" checksum="9761395199B6BB13" modified="2023-09-13" version="1">MDMGHGHSSTDATSGMSMSMVFTTDHSTPLYSSAWTPSGTGAYAGTCLFLIILGVISRLLLAYRYVVEQKWHDKAVQRRYIVVAGENAVERERRLEPSAEKSDEATLTTRGMDESVRVVRTARRSLQNTPWRFSTDLPRACIFTVQAGVGYLLMLAVMTLNVGYFLSVLAGLFVGELLVGRYTFADDGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9T8</accession>
    <name>A0A9Q8L9T8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">palmitoyl-protein hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the palmitoyl-protein thioesterase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757932.1">
        <property type="nucleotide sequence ID" value="XM_047901771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9T8"/>
    <dbReference type="GeneID" id="71982501"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02623"/>
    <dbReference type="OrthoDB" id="10263094at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000107">
        <property type="entry name" value="Palmitoyl-protein thioesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002472">
        <property type="entry name" value="Palm_thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00414">
        <property type="entry name" value="PPTHIESTRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040293500" description="palmitoyl-protein hydrolase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="8">
        <location>
            <begin position="472"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="64939" checksum="99294552C8F80A0C" modified="2023-09-13" version="1">MRILSLPAALSIIALTTALPTITSNDKPLPLLIWHGLGDRYDADGLHSVGDLAKEIYPGTHVHYISLDDDGNNDSRATFFGNVTEQVAQVCEDLKNNTKLHDKHGIVRADALGFSQGGQFLRGLQQRCDGVSIRSLVTFGSQHNGIAQFKACGTWDFVCKGALALAKGNAWTEYVQSRVVPAQYYRTLNETTGLASDDYLEHSNFLADINNEREVKNETYKQRIASLENFVMFMFEDDTTVIPRESGWFAEVNTTSEKVQPLKERAMYKDDWLGLKKLDKKGGLIFQTTPGDHMQLEEDVLKGTFEEYFGPEKGLFGNMNMHACGAYNYTFRVPTPPRIVVPPPALNADAVPEIAIHALRNASYNFLSQVNYNNLVQSNAPLEWTYERRREAQTILPFLCLGPMTAAKDETWLRKEGVTMLLGVRQKHSFESKLMNGALRKAREMNIEHYTVDLASNQELASNFDKTTAMINDHLRRVHEKTAGQQMGKVLVFCESGNERSAGVVAAFVMETHEDVDYIKAVQLCQAQRFCVNFDDNMKRLLQGYWDILMQYQLQWFCFPQRGIGVRDEAAGWLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9W9</accession>
    <name>A0A9Q8L9W9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757976.1">
        <property type="nucleotide sequence ID" value="XM_047901622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9W9"/>
    <dbReference type="GeneID" id="71982352"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02474"/>
    <dbReference type="OMA" id="NIMFATR"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34515" checksum="E764209E96A9CB3D" modified="2023-09-13" version="1">MDKFKSWTSTVSNSITPFATQSQQWIKERTGNATEKTELPHDYVELETRIDALKQTHSKLLAATSQYANEAYDYPPNVRESFQDLGRSISDKVNLLSKASNASEAQAAFTAPPSAKPQPKTFAHAIARACLSGSQTISTATPQGSTEPDPLAQGLEKLAISSEKVGEARLDQDEKIQGKFLAGWSTTLNQSIKSADKARTAVQNARLQLDAAKSKAAAGGKHEESYTEQQRRAIEQAEDQFVEKVDEATSIMRNVLDTPEPMRNLVELAKAQAEYHMRSAEILEDVAKQLEEIQVEQETEYRKARDGQEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9X9</accession>
    <name>A0A9Q8L9X9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Calcineurin regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein phosphatase 2B regulatory subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of a catalytic subunit (A) and a regulatory subunit (B).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the calcineurin regulatory subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757785.1">
        <property type="nucleotide sequence ID" value="XM_047901722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9X9"/>
    <dbReference type="GeneID" id="71982452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02574"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000047">
        <property type="entry name" value="Calcineurin subunit B type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="198" mass="22428" checksum="96FD8D3BC4D4645F" modified="2023-09-13" version="1">MGNGIQYNSRQPTHSPPQQQHDVDMGNANSQMLDSIVSGSNFDRDEVDRLRKRFMKLDKDNSGTIERDEFLSLPQVSSNPLATRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGYISNGELFIVLKMMVGSNLKDQQLQQIVDKTIMEADLDHDGKISFEEFTKMVENTDVSMSMTLDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAV8</accession>
    <name>A0A9Q8LAV8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sphingomyelin phosphodiesterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758395.1">
        <property type="nucleotide sequence ID" value="XM_047902598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAV8"/>
    <dbReference type="GeneID" id="71983328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03450"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF27">
        <property type="entry name" value="ACL091CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040512716" evidence="3">
        <location>
            <begin position="25"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="317"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="675" mass="74182" checksum="C2AC05410806FDD7" modified="2023-09-13" version="1">MDGNFQAILLLSIARMVLFERVLALAPLLLQLGDAQSRYGSAAASAPGPTSVFSSYYPSPTGQEPQPAVYHPVLNITFPANLTNPDTIPDNDPDPVYYPKPVANLTNAEQQKVTENVVKQVKEVIASPCFTSNCSKCIAALSLAKGAADFAPSLVPAAMVSLCNETSLHSASTCKEDFEATTFGAIWTQVLAFADVSGLDGQYICHSISTSFCPAPLTSSLNTANLFPKAKPENATAPKASGKRVKVLHMSHFHIDPRHKVGSEGNCTSALCCRNNNDNTALPHGQISFPAPPFGYFQCDTPYDLGLGCDDPLGWTIYTGDLVSHDPQTQLNRAYTEYAETSVYNYLFKKYLTRPVFPVLGNHDTNPEAIDAPHSLPGPLGQQMSWNYDHVAALWKHEDWLDDAAENQARVHYGAYSIKNHYGLRIITFNSDFWYKSNFLNFINTSNPDVSGTFKFVIDELQAAEDAGERVWLFAHVLSGWDGSNPMPNPSNLFYQIVERYSPHVIANIFFGHTHEDQSMIYYANNGTKQSLDTALNNGWIGPSVTPLTNLNSGFRMYEVDTGSFDIYEAYTWYTDVHTFSNMTRQGPTFELEYSTRETYGGAAGWPQDAPLNATFWHAVTEAMEKDHSLVSKQNTLTGKSSIKKSVNMRSGSVALGQQCPQGYGSVQSAFSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAW2</accession>
    <name>A0A9Q8LAW2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dibenzothiophene desulfurization enzyme C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_02860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758424.1">
        <property type="nucleotide sequence ID" value="XM_047902008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAW2"/>
    <dbReference type="GeneID" id="71982738"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02860"/>
    <dbReference type="OMA" id="HNWDNVG"/>
    <dbReference type="OrthoDB" id="5356974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008470">
        <property type="term" value="F:3-methylbutanoyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000020">
        <property type="entry name" value="Putative acyl-CoA dehydrogenase YdbM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000025">
        <property type="entry name" value="Related to Dibenzothiophene desulfurization enzyme C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013107">
        <property type="entry name" value="Acyl-CoA_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08028">
        <property type="entry name" value="Acyl-CoA_dh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="4">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="424"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="495" mass="54247" checksum="B4D978CD6F46EAF6" modified="2023-09-13" version="1">MSTKAREYTDPSDYNQHHERFEQEGLPKSQQAWIQRAKEVSDILAEDAAQRDIDNKSPRAEVSLLKSAGLLKVLGPEKYGGGEQSWETGYKVIREVAKGDGSLGMLLGYHLLWSTTANVVGTDEQQESVQQVIIQNNYFVGGAVNPRDSDLKISSEGDEIVFNGFKNFNTGGVVSDLTVLEGVLDGTEDHIFTFVKTIQPGISFLHNWDNVGLRLTESGGVKINDVRVPWSDALGWDAQSKRPVQEVLGIPFASMLLPTIQLVFTNFYLGIAQGALGAASQYTVNSTRAWPYGGDNKDKATDEWYILERYGEYRAHLAAADALTDRAGAEIANLYREAGQYGSVVDPSIAAKRVNPNYLANGIDETGPLNKTNPPYTISTAASFQHLPAESQTNGHANGNGHSKSNGRAGISALRRGEVAAFVAHAKVVTTDTGLAVTSGVFEMLGARATGKKYGFDRYWRDIRTHSLHDPVAYKKREVGRYQLLGEIPEPTWYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB44</accession>
    <name>A0A9Q8LB44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758370.1">
        <property type="nucleotide sequence ID" value="XM_047901865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB44"/>
    <dbReference type="GeneID" id="71982595"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02717"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14543" checksum="7E46DEA24911DFF7" modified="2023-09-13" version="1">MKSNIITIGLGTIAVTGVAALPVLNQDIAVSLDPRAELAIETPQGADLVARAVPDVEASQVADLVARDEEDYRANGAVQDKGLGYSPNSYNGRYDHDWEQWGWSDFLRRLIMYYRRDKYTCGFGFENHGMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBD3</accession>
    <name>A0A9Q8LBD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758664.1">
        <property type="nucleotide sequence ID" value="XM_047902753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBD3"/>
    <dbReference type="GeneID" id="71983483"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03605"/>
    <dbReference type="OrthoDB" id="9973183at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="17071" checksum="C6252B036F36C451" modified="2023-09-13" version="1">MATKRLIKELDAFRRSPSSALTRLEPQSDEDLFHLVATLKGPEGTAYEGGLWHLTISIPPTYPNTAPEIRFQTPICHPNVNFKTGEICLDLLKTSWTPAYGVVTSLEAVSQLLSAGGEPESPLNVDIARLYRGGDWVAAEGLVRFYTRVLAMGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCR8</accession>
    <name>A0A9Q8LCR8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759377.1">
        <property type="nucleotide sequence ID" value="XM_047907283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCR8"/>
    <dbReference type="GeneID" id="71988013"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08135"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="11655" checksum="5992CE94D328FA7A" modified="2023-09-13" version="1">MSHNGVGDSDYMDSRKFMLSVLRARCICTRCPSASSSSSLRVVVVVPIVKCAVGGCEPPKGKRSEVELYTRQQQIRHNPTGAQQTQLITVLRNQIEAMPPYSSMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCR9</accession>
    <name>A0A9Q8LCR9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759461.1">
        <property type="nucleotide sequence ID" value="XM_047907920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCR9"/>
    <dbReference type="GeneID" id="71988650"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08772"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="198" mass="21122" checksum="0811E4CECDEFB9B6" modified="2023-09-13" version="1">MLSNDRAAFSLASMGVRCKSIAARVELVANFDIIADHHFKHTSHHIINTTTARHTTPSPRHTTPAARIPPAMTTTLLTTDSTFPSTNLDDMLSKPTNTAAPTTPQLHVKNHAQGLLAGHNSQVLSMFNLADGSIYASADHSIVINGPIFGAETPPSSALAGQLNAALAMLVLVVVVWGMLEVKRGIEDAFSRIDVVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD16</accession>
    <name>A0A9Q8LD16_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08654</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759657.1">
        <property type="nucleotide sequence ID" value="XM_047907802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD16"/>
    <dbReference type="GeneID" id="71988532"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08654"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="225"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="225"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="577"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="698" mass="74875" checksum="CE4C62ABA6A3338D" modified="2023-09-13" version="1">MGSAVLTMEQGPILQQHLPIHDYSLSSDHDYNEQYSGHAHHPGYATTGSVDSLRRDGSAPIQAPTPFTFTATNSATGARFLPDRGVASETTSYQSSNQFGDSSSGSISTSPASAASSLAYTNYQQNHCTSVPSYGAPVQLPQVFVPSAYGNTRVPPILDSSGMLPPPHPMRSPLSSSTNATERETYTSPSLARPQLSPGGYQPGYASYPETPRTALSSITGLSLSNASYPYSNGHHSQMASPPYGNQQNECGNFPWPNLEIHAEMTCEGQAVTPEVHAKVEKGFFMSSVDSKWTCYRRNYFSVQCHFELHPNITNGRMQLKRNNSTHSETIQAMGMRLSAAVDGSAGKNIELVQHTPKRDAGPKSKIEIVKVSPTPSNGRGEHTVSPHGIYQVPMSTFHPTGSIPGPNLPFQNQPEPGSPSNAAAQASQASSNYPYSASAASHLPLPGQAANHTFERVQFKQATANNGKRRASQQYFHLIVELYADVRKSESDSPSWVKVAHRVSEKIVVRGRSPSHYQNEGQNCNGRTGSSGGSSSYSTTGGAATYGGGIGSSGFRSSTGYTGGLAGASYRNNTYGFHPSPEHSGSSASSVDGGAQDSDYPPDAVMSDTERSEFQNRDEYRYYPGTIYEGVPQGGLPLPKIESTARYSTDPSSWAVKHESFDASAGAQQWPVNGLSRFQGVESSRGYYPADLAHQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD27</accession>
    <name>A0A9Q8LD27_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759542.1">
        <property type="nucleotide sequence ID" value="XM_047906983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD27"/>
    <dbReference type="GeneID" id="71987713"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07835"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="529" mass="57359" checksum="E0A035CCA7DEBC95" modified="2023-09-13" version="1">MTVELIKKYPHLVQQYMRPKPKGASITRLPGERDPVVVIGGARLRASAVLDLTWINYLRHEDITSYEATTISPASAPSLLKALLSCRVGSLQNFASAYNLQIESHFDVKQADSKEETTKKVDHPVDKHTAANSKSSSNPLPVISFEDVAELKDKGAETSSLDSRRHGSASAAEKPRTVRDGRADTSETPPKKTGEASTAEQTADANAEEGMVHAATAKSAGHSKDGEAAPRPIASSDTQQSIANTNWQAPDKPVQRQAVSTAQKQSSLPSMQGSETLGGIFRRPMAPNTSLPSGGTSSAAMSGLASVTRKGLELDGVTDPELNTRSVDDGRIAARLDRERNIIGTRTSATPGRDSFDRQQNFRDQRANPRPRDQEQTTRGYVGEGSSYRPNYSVRTPTGDVFDPRVGRHDSRPDGRDHGGEQREQRGERRGGGSTQGDEREGGSNGKRRGHSDDDGDHSYEGQSKESKDGRKKAKLESQSSFSGQSERDGNKRHPPGDGRRGRTEGWGLRRTSWLLIECLKALEGCVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDA1</accession>
    <name>A0A9Q8LDA1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">fumarate reductase (NADH)</fullName>
            <ecNumber evidence="7">1.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NADH-dependent fumarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_08442</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="7"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759625.1">
        <property type="nucleotide sequence ID" value="XM_047907590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDA1"/>
    <dbReference type="GeneID" id="71988320"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08442"/>
    <dbReference type="OrthoDB" id="10252157at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000007">
        <property type="entry name" value="NADH-dependent fumarate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="550"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="493"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00067004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO15259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="634" mass="69032" checksum="1C53C895DD135EB5" modified="2023-09-13" version="1">MPQRIIVVGAGLSGLSAAHTIYLAGGNVVLLDKNNFMGGNSTKATSGINGALTRTQTDHKIADSVKQFYDDTIKSARDKARPDLVKVLTYQSAGAVEWLQDVFNLDLTLVSRLGGHSYPRTHRGHDAKFPGMAITYALMQRWEELCEKEPERVELVKKAKVMKINMDGNRATGVTYKFGHEDVTVDGPVVLATGGYAADFGEDSLLKKHRPDTFDLSTTNGNHATGDGHKMLMAIGANGVDMESVQVHPTGLVDPKDPTAKTKFLAAEALRGEGGLLINSKGERFVDELQHRDFVSDKMWEEKKKGNWPIRLCLNSKASNTLDFHTRHYSGRGLMKKMTGAELAKDIGCGEKKLGETFKAYNKYANGEEKDPFNKKFFHNFPVEVNDDFHVAHMEPVLHFTMGGIEINDKSEVLNSKGEPFEGLFTCGELAGGVHGANRLGGSSLLGCVVYGRVAGTSSSKYLFQEVLNSEGGQAASRAGQISLHIDPSTPGKFTVEWGTGSGASSGSSDNTSKLQQHGQKSAAPVMDGKGGDPGKKQETNDVKNFKVPEDEYSLEEVAKHNKKEDLWIAVKGVVMNVTDWVDEHPGGPQALFSHMGKDASEEFEMLHDDEVIPKYAAGIVIGRVKGQEITLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDI2</accession>
    <name>A0A9Q8LDI2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759866.1">
        <property type="nucleotide sequence ID" value="XM_047907434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDI2"/>
    <dbReference type="GeneID" id="71988164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08286"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="73" mass="8294" checksum="34AD49F62EF2049C" modified="2023-09-13" version="1">MNVARARRRGMATAAVCSMRTMYTSQLPGRCLRSARGRPWLRRVFQRTGGATSLDRRVGLDLVQTDREVDRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEG3</accession>
    <name>A0A9Q8LEG3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759554.1">
        <property type="nucleotide sequence ID" value="XM_047907680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEG3"/>
    <dbReference type="GeneID" id="71988410"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08532"/>
    <dbReference type="OMA" id="RGIECNF"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="30762" checksum="585C95B28382F840" modified="2023-09-13" version="1">MGSKKMNVPKSPRRPQVANACVACRTSKVKCSGKHPVCSRCRSRGIECNFDVSAEGITKRQHLQNELAQLSGHKQGLERANAIIDVLQHGSDSEAVELLVCLRTGHSVDAAFNHVQQKRQGTASNLADPALPSAAASVIADTTPSGPPRLANNVSMQSVSSSIARPQADSWSFPPVSNSTGNNLPTPTIATDQSTAWPYPPISNETQYLQHDMGTNAYTYQPTEDDSQTQQFGLATRVSPLSTCSSSRASNAQDSYIQQPYSPEHLFFESTPQERANPAMYSNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEG9</accession>
    <name>A0A9Q8LEG9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04980</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760095.1">
        <property type="nucleotide sequence ID" value="XM_047904128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEG9"/>
    <dbReference type="GeneID" id="71984858"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04980"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="OrthoDB" id="15235at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000002">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="376"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="547"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="698" mass="77593" checksum="48E78AC81A648E73" modified="2023-09-13" version="1">MCGIFGYINYLVEKDRKYILDTLVNGLSRLEYRGYDSAGLAIDGDKKNEVFAFKEVGKVAKLKELIATEQPDLTKVFDNHAGIAHTRWATHGPPSRTNCHPHRSDPKWEFAVVHNGIITNYKELRALLETKGFKFETETDTEAIAKLAKYIFDQHPNIEFTTLMKAVIKELQGAFGLLMKSVRFPGEVVAARKGSPLVVGVRTQKKMKVDFVDVEFGEGGDVLPAEQASQNVALKKSNGLLGGNLLAPPDKSLLHRSQSRAFLSDDGVPQPTEFFLSSDPAAIIEHTKKVLYLEDDDIAHIHEGQLNIHRLSKTDGTSNVRAIQTIEIELQEIMKGKFDHFMQKEIFEQPESVVNAMRGRLNVEEKTVTLGGLRQYISTIRRCRRLIFIACGTSFHSCMAVRGAFEELTDIPISVELASDFLDRKAPVFRDDTVVFVSQSGETADSLMALRYCLERGALTVGIVNVVGSSISLMTHCGVHINAGPEIGVASTKAYTSQFVCMIMFALSLSEDRASKTQRRMEIMEGLGKISEQFKQILKMDQEIKELCLKFKDQKSLLLLGRGAQHATALEGALKIKEISYLHCEAVMSGELKHGVLALVDENLPIVMILTRDDIFAKSLNAYQQVIARKGRPIVICNTGDKEFPGDKTDKIEVPHTVDVLQGLLNVIPLQLMAYWLAVAEGLNVDFPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF48</accession>
    <name>A0A9Q8LF48_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_04409</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760767.1">
        <property type="nucleotide sequence ID" value="XM_047903557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71984287"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04409"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000235">
        <property type="entry name" value="Probable nik-1 protein (Os-1p protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000001">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="203"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="298"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="390"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="482"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="574"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="666"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="740"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1109"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1245"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="692"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1245"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1295"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO16401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1307" mass="142968" checksum="235CB8546749583F" modified="2023-09-13" version="1">MPHEETSAAVASILSNFAKQYAAPLDPESFPASAIANGVESNKITLPGDDTIEKRTLERELTALNLRIQFLEARATGGASSLPITPNEPISSAFPPDSPTSTRSAGAANPRQRSASWVNSILAKGEGEPPHSRQLTEEQFNFLREHIEQQAQEIKSQKDFIDGIKSQLTHQQSATKAALDTLGNSQSIEQLKREIEKNAQINATYQKVLREIGTIITAVANGDLSKKVLIHATEKDPEIARFKHTINRMVDQLQEFASQVTHLAREVGTEGRLGGQAIVPGVDGIWAELTQNVNVMAQNLTDQVREIAVVTTAVAQGDLSRKIQRPARGEILQLQQTINAMVGQLRTFATEVTRVSRDVGTEGVLGGQAQIEGVQGMWNDLTVNVNAMANNLTAQVRDIAEVTTAVAQGDLTRQVKAPCKGEILALKTTINSMVGRLRQFSQEVTTIAREVGTEGRLGGQATVHGVEGTWKDLTENVNGMAMNLTTQVREIAEVTTAVAQGDLSKKVEVEVKGEILALKNTINTMVDRLGKFAFEVSRVSREVGTEGVLGGQAEVENVEGKWKDLTDNVNTMANNLTSQVRSISDVTQAIARGDMSQRIKVHAQGEIQTLKDTINDMVTRLDAWSLAVKRVARDVGVDGKMGGQAEVEGITGRWKEITTDVNIMAQNLTSQVRAFADITHAAMKGDFTKMINVEASGEMNELKNKINRMVLNLRESIQKNNQAREAAELANKTKSEFLANMSHEIRTPMNGIIGMTQLTLDTELEQNQRDMLNIVFSLANSLLTIIDDILDISKIEANRMILEEEPFSLRGLVFNSLKSLAVRANEKDISLIYDTGNSVPDYIVGDSFRLRQIILNLAGNAIKFTEHGEVRVRIDSDHTMPCNEGEVVVKFAVSDTGIGIHSNKLDLIFDTFQQADGSTTRKFGGTGLGLSISRRLVTLMRGKMWVESTYGAGSTFFFTCVVRLGPNDPQRVAPQLQQYRKHKVLFVDNGFTECADDIADNIKALDLVPCVVGNGRTPPAELNPDDQYDCVIVDNGDTAQKLRSLERFKYIPIVMLAPAISVNFKTALENGISSYMTVPCLPVDLGNALIPALEGRAAPISADHTRTFDILLAEDNAVNQKLAVKILTKHNHKVTVANNGLEAFEAIKTRRFDVVLMDVQMPVMGGFEATAKIREYEKMHELARSPIVALTAHAMLGDREKCIQAQMDEYLSKPLKPNQLIQTILKCATLGGALLERQKDGRSLLMDEEKSSDSSPDHNRLMTPKRPGVGPRGATESGPSGLESPAIVTADQEDPLSREVLLRSHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFZ8</accession>
    <name>A0A9Q8LFZ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761087.1">
        <property type="nucleotide sequence ID" value="XM_047903225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFZ8"/>
    <dbReference type="GeneID" id="71983955"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04077"/>
    <dbReference type="OrthoDB" id="3796964at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23597" checksum="14E0A5414CE04E0C" modified="2023-09-13" version="1">MTSNSTIQHMPHNSPRATADHYIRHLRQLPSLPRFSIYLFGPQARFRRWLRKAKKAKQKKQHFDDALWQQGLEVLGDVLLPNAYIGDRHTIRMVQHRLIHDEEEADAWTPYYPEGAVIEVTTRNFHTKVDRTVEEVLGLLLHEMCHAVLWSRSCACEDCKDLLLYKGGHGEEWEDLAGECNGRVCVYSAFRRVSSGDSVEWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG28</accession>
    <name>A0A9Q8LG28_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761132.1">
        <property type="nucleotide sequence ID" value="XM_047904265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG28"/>
    <dbReference type="GeneID" id="71984995"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05117"/>
    <dbReference type="OrthoDB" id="3935740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040157760" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="55464" checksum="A6681DA7384DB4B3" modified="2023-09-13" version="1">MSTARASLLMALVGSTLADHSLAERQTTPICGITGTESQLPSAVSVLRANRSPTGCINFCKKSRSCRSFAVSSTFCWLCNHAGGTNFRYNAASNYKAPHLIQQLPPARPVAVLCPLLSPTFKVDCKSKITVVQNNQPFSIDKSPRTIRTAAGTTAEGMLAHPLKLSSTSRARRRSIYSEGLVPRCVKNLEQLVCRDKKDATPPTANGWSSKGSDWIPDFTIYGACIKAAELYANVVASPIGAKAFIDTGRNRCTCMCPNPTLLCGTTAENAYCTNIFSNERENCGGCGRTCPEGTKCKGGNCVCPIDQCGSTCLDLRQNPFHCGACNNACLSAEPCCTKGACIAAPKECVAGLSNPTSQSDFEQDWKVDACADCRTGYDEGYDKNGESEVFVVTPKDKGHSVVEFSTMMTACPGQNYKLGFGMFRDQGSDSCELTIPAGGRQLSTINILKWNENGNEQRLQDRTIDAGSFQAGGVVQKNRLSLNVPLAFSMKCSGVFADSFDGQNQVRFGHFALTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGC9</accession>
    <name>A0A9Q8LGC9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761487.1">
        <property type="nucleotide sequence ID" value="XM_047903232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGC9"/>
    <dbReference type="GeneID" id="71983962"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04084"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040294420" evidence="1">
        <location>
            <begin position="24"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="21234" checksum="27027E723F6DCD92" modified="2023-09-13" version="1">MAAWRALAVIFDFLAACCNTSFSATRTHTNNKTYTSLDMAITYTANQLLSRRYILTAASTPITLSIDLMALRTVQDLVAQRELAEAQRYATAINTYDDSSIDALWQRIININRGSGWWPLSRAATHARQQLTLRRNLREFNRARAAHHHQTSTLSPAERWALRRARNIRRQQQWQRRQARRHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGK3</accession>
    <name>A0A9Q8LGK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <location>
            <begin position="47"/>
            <end position="71"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10597" checksum="D47CE0665E3254FA" modified="2023-09-13" version="1">MAVPRDPAFWKRFSVAVHEDEETGTQELKSPDSWLARQNKKKSQRTYCCYGFWIGFLIFIAAVVAVIIWLLSSGMLTGDHQDVTEVDLGGDGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        </source>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:calcium ion binding"/>
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    </dbReference>
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        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CCDC47"/>
    </dbReference>
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        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
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    </dbReference>
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    </dbReference>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI99</accession>
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        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
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    </reference>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LII1</accession>
    <name>A0A9Q8LII1_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="84"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="181"/>
        </location>
    </feature>
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        <location>
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            <end position="227"/>
        </location>
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        <location>
            <begin position="314"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="792"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="918"/>
        </location>
    </feature>
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        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1144" mass="125062" checksum="0D0CA55AFD5ADDDB" modified="2023-09-13" version="1">MTTTGPIRPIPRRVSRSSGPERVYAQNIARLERTAEEISMGGSDIGEEIRKMNEMEKERSRQNSIQSSHHGDISVVRPRPPTRMGSTTSLYAANSIVEANNTARWGGYSPPAFITSPVGSVRSGASWSHASAMPSASRTTSSRLAMVEPMQEGNPLNSPLAPSSVSLYSQEHQMSRQASQTSFSRRYDQIAGEIEEQLQTIPATPSPHPPEHDDCAARDAPDRPHSTDTYREAQLAFKDFDGVHYDPDSEEYVLEDDGGNEVRRVSARTSSGSLLGAASLLRQSKGKESMLQYGAPPPNQNMVYYPAPVPRMLNMPKRLSQQPPPSVQAKRRSQMLQELSKQNRESAPWIPPIAFDEEGNQSQADVRSQRSGSQSTHSQDPNQPRGMLNERMSMHNPQNLPPQLRASVFFEHPSVTHDVELTNESAVATLDSILAASATAPVDVFTHHPYAGDVRKSVYAPEGHQKRRSTATLAKIPSEEQETEQQKKIKKRRSSSIGNFFRRNSTDLNGEMKEVARSRPVSKGSMLDFNESGNKLRKRKSQMSMGSMGDEVQRAERSNRPDSEIMAVQRRASMMSGGLIAQAANGPVSDEREEQDDFVREQRIPSDPRPGTAMSRNKALTEGQQVAADFEAEADNSDIDLEDPIYAQPTTLLAELQVRKAKLKSRNRTAATAYPGGMHSTLLQLDAVEAINSRKRQKQKIALAWEDPNSRAEAEAQLEAEDEDVPLGMLFPSKEGLIARRMGDGRDWDRPLGLMAKREMEENEPLSSRRTRLNPGARPLRQQSSMNLSQLHLAGQPAADEAEDPGETLGQRKARLRSKEALDSAIKDVAFGEGERPDSTFTADVLDQFPELSLNDDGTKKEDQVKASLGGNQATAETVPEEETLGARRARLQREREASGEHAPQEEQGARPALQSRPSLANLLSSNPVGQRPAMNRDQQMSQGTLLHAHGIQQAKSKQNLLATNMRHISGHSPTANGMSHPSTYQPAGAVFDPSLPAGHRDFTTGLLSAQRSRPANGAFSGGAYGNFQGAGLQTPMSMSGMGGSNPYFASPTAGLGGYGNTMPMYMPQQQQPQQMNAPAYYALNGGHASMMPGMVSTAGYNVMTGTGQYAYNAQNGLGMVDGPPLNPNQRAAIDRWRVSVAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIL5</accession>
    <name>A0A9Q8LIL5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIL5"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="20134" checksum="977DA20FF4EAA8B9" modified="2023-09-13" version="1">MTRHPLTSEQSFGLLDLAPEIWSTIGKLAVDDHPRPHELFHPYRGRGAPHQPPITRVCRILRGELLPYFYRTWGSHMIHWGNAGSTGRWLRAIGVENRRHVRGAFFLASSAHEAVHGKKDLQRRLKRTWAFDLRVQANDSASRDSSDRVIYYDIAFIGWPWQWQDPCGVDGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIY8</accession>
    <name>A0A9Q8LIY8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762867.1">
        <property type="nucleotide sequence ID" value="XM_047905779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIY8"/>
    <dbReference type="GeneID" id="71986509"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06631"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040193450" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="7946" checksum="8CB53D44DF0FD8FE" modified="2023-09-13" version="1">MNTTLVIASLFAIISLSIAVSPAVFFSADGDAQCGRECGGVCSAASSKCPRSSVGWCFLATDAGTALSDEESTARFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2U2</accession>
    <name>A0A9Q8P2U2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755393.1">
        <property type="nucleotide sequence ID" value="XM_047901425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2U2"/>
    <dbReference type="GeneID" id="71982155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02277"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="281" mass="31562" checksum="6E47CD97C2F32719" modified="2023-09-13" version="1">MLPILSLATDHLHLVRYLPDHAAIQRGSQAIAGPIGPFLTLASAYLSEHGYSILSLITCLLIGGLVGFCFSESSKTGTIIVGDWTRGRTQKTRMAMPRVPVTSRKKNHWKEELAIKNARIKSLQSDVNEEKRHSAYVEGELVDLSAQLRQKDILMAACNQNIETQNQELAALRSVHEHATQRLTETITDLGNHLAESIIATEEQAKRMHTEANVLVHERDAALKAARKAKHDLESFYCSKELRGYTYTSTREHHRQQTYISSLEGRVQNLSEVLSAEREQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3D7</accession>
    <name>A0A9Q8P3D7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756199.1">
        <property type="nucleotide sequence ID" value="XM_047900101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3D7"/>
    <dbReference type="GeneID" id="71980831"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00953"/>
    <dbReference type="OMA" id="PEYLDTM"/>
    <dbReference type="OrthoDB" id="5423516at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="45"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1018" mass="110977" checksum="57005E825A53E467" modified="2023-09-13" version="1">MPTLKQITCCIQLGPSDTKLKEYGHRFTDGGVEAFIAVPDTKVPFNVRVRSSGYIAPGLAAYVFIDGQYQCNRNRQNLQLPAPGMGTRDYEVDFRLRQKEEKTAEGSFVAREWTFAELKTGNADQAPDTNPAFAKNVGTIEVVILRCKGDALHGPAETVIDGGDETGFAATSRAPSVAHSAPAAKARDSARPAPKAPAKEPSVAADDGLGGGMFGLFDGAGDDPDYRRHMPGRYDHRSPLPRYRQDLRNDNRYSPRPFTVHGDSGDRNAGDVRAHAYDVRPRTANDHYALPVTPHAGYDFQQRRRFVPHTVQQSPTQRHENRPLHNAYTPRAPPSSLLPRVSAPEGFSFVLETCKEMDGLYRLSFGEREKCAELAQEAHAWENDPEMYLSAMKALRHKQQELGKADEQLTAMRQAIYARMRRMDPKTWQYTRDFLVLEARLFGPNDPHMQQWPDPRLQQHLQSPELGTTRTSGAIDDRTGHNPRSNDGWEEQGHGETNGGLQQKQMRKQSGAHSARSSIQKPAGDGWGASSQKGGGNWATDDVDNQANDGGAGDAWGGAAGGNDDQNKDDSKSESKKDGTGAWGANDNGQSNNEGDNGWGANNDKNDSKQDGGDWGGGGDNNDTRSKTAGWHNNDGAGSHKSRSQNNDAWAQSTKDNKSQTAKSKIDSWAKGNQKSQSAAWGNQSQAKTQQGGNGGWNQVGAGEGQARSHASSRRPARTTTSVALEPVIKPYWADWDKPQQGTSRPRPQPRDPYEYPPPATVLAPSGRARDLSHGVQAGRGADYAHKTFRPEYLDTMDKPYAIFTFKYRSQSTLEKLLRRKIDTSDTKRAVDEAEKEKLMRLPKDELVQEMLKMRLKPSSSGTKPASAPTAPSNTGWGVKAPSQANWGGDQQRDDVKPSDSVSNHTSVKRGDGGGGVWAAAKSKANDGGWDSGKNDNGGDAWNQHDKQSRKNEAKKQKSKVSAWDAAPAAGENDQWAANGAGKDKASSRSESHFAPDDPGLQTAGDGKLSQGWADAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3K5</accession>
    <name>A0A9Q8P3K5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_01410</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
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        </source>
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            <begin position="22"/>
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        </location>
    </feature>
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    </evidence>
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            <dbReference type="EMBL" id="UJO12718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="313" mass="33754" checksum="1E3D6832C715DE70" modified="2023-09-13" version="1">MTVAKMLGLASIATLIASTIAAPASSSVEPVTRQAVATDYATCTVGHIGNTNLAAYDVHIGRPYNGGAGCGYIYYALSRTVTINDYKCLDDAAHTGTALYLTTEDNAASNDQIIFGLQNAYPMIPFKAHRICFKFYDKRSEQEPSKRSTPEPENPWCIWGGMHYLSVNDITTGNDIFDGSKDFCAAHHGAIPTTHSSTQEYKIAPDRSVLFSMSNFCEGVEITEKECMDHFWTAGNSCVDDKIYSEGVRMYGATFMTECYGFSVVPFYPAGRVEPLPLSQCHAITCAPGAEGDATCRSSGCANGCSSDSKCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P494</accession>
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            <end position="77"/>
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        <source>
            <dbReference type="EMBL" id="UJO12733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="98" mass="10708" checksum="0B2E8C9F414350E4" modified="2023-09-13" version="1">MGMPIRRSFSARHLPPSQRVSSEEEKKRGSPQPPSVSSPLRTSPVRTHNATSGAAFKTSSSSPTKAGPSLQPTQTKCQDTKPIIIIDDDKPNDLKRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4S1</accession>
    <name>A0A9Q8P4S1_PASFU</name>
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        <recommendedName>
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    <gene>
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    <organism evidence="2 3">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2" key="2">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="63"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="193" mass="21200" checksum="A7D0B6AE1B6DC479" modified="2023-09-13" version="1">MSRTLVMHSLLRGIVCSQQSNLGERSNDPCLDRRQSYMDDGAVLGEFELGPPFHPTNLRRKQPWTAFVNAIRPSRRLSSTPRAVQWKCNDNTTGWKALLGDAAGSSDPRAVLEYAAPARAENLVNLPPTFIECGQLDIFVFEDVALANRLVQARVPVELHIYPGLPHGYQGLAPNISLTQASLANVLRAIANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4V2</accession>
    <name>A0A9Q8P4V2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757836.1">
        <property type="nucleotide sequence ID" value="XM_047902564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4V2"/>
    <dbReference type="GeneID" id="71983294"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03416"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="77"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="449" mass="48618" checksum="FD401D91412BA79F" modified="2023-09-13" version="1">MAAVPLKPWMAVPQKRLVDARLIDPKSGDVHEHVTIDLWSGVIRHMSKLSGQPSPGDDAMSWTQGSDIVVVNLEGRFVMPGLMDCHVHLATPSGEDGLKDTVNQDPDTSLIRQPYLAHQMLKRGFTSIRDCGGAGLALEEALAEGLYPGPRLFTSGHGISQTGGHGDLRSSKDNEYACCGGNTHGLGRIADGVEQCLHAAREELRQGADFIKIMVSGGVVSPTDKLTSLQYTPEEIRAFTKVASDSGTWVTEHAYRPAAIRNAVENGVLGIEHGNLIDEPTAKLMAEKGAYLTPTLVAYETMASKDFPGFLPPSIATENIQVLEAGLKSIQIADAAGVTMCYGSDLLGPLQIRQTGEFVLRRKAGLSALKVLQSATVNAAKMLRHEDKLGRVKEGAMADLLILNANPLEDISVLDRPERHLLAVFKDGRCLHSRWPKFTPEIERAELIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4W2</accession>
    <name>A0A9Q8P4W2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lactose regulatory protein LAC9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757744.1">
        <property type="nucleotide sequence ID" value="XM_047902936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4W2"/>
    <dbReference type="GeneID" id="71983666"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03788"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="842" mass="94061" checksum="3AA49BDDA9FAB9D2" modified="2023-09-13" version="1">MYHTFQAGSTSGAPEGEGGKATRPVGGSRRISTSNACVECRRRKIRCDGTQPCGQCQWYQHPELCAYSKPAQRVVPSRKIVDKLQSQVDQYHSVFARLFPGKQLEDFLSLPREGLINLAVTLPASNPSVGNTPEPLGNIAEIVQRSDGAESLEALEQAPEQDPENDEVKRLRDKIQGISDDVNGLSISIDKASTYVGISSINAAMKVIFRTAPIARPFISNRSAETTEPSRANTPPPYVRDPDPNYLPPADVGEKLIDFYFAHIHVLMPMIDEDQFRHSYLYGTRTDPPWLALLNMVLALGSLASSTCDNEDHIAFYQRARKHIDAESFGSGSLFVLQALSLLSGYYLHYLNRPNEANGIMGATLRMATAHGLHREYSESHRNSPPGGTVIMSGLEVPVEIRRRTWWSLYCLDSWASITTGRPSLGRTGSGITIQSPRVPEQMNNAQYLASLRLLPIIHNIGFCKIATKVQDLLAAHSMIGYDDLFVLDSELEKWHDDLPPILRDVVDRPARTQRTSSISGNYKHISPKPPTSSASNKNPFDFSQPPERDKTACPEVLKTPRAIMHWRYQNLRILMHRPLLLATALRRTPYANMSTEEKLAVGRCRIVAGQAIADIDATCQEDLIAGWNAVWLMYQAVMVPLVSLFSVLALPPATANSESPSLTPGGSDASAIIPGSDEDTAKWKHEIERSIQFFDRMQHFSVAARKSRDVVQRLYDATKYVSEHHAQLHQQQQDMLRRRHSAAHPQPLNTDTMGAYEAVADPNHMALNAPDMVQNYAFMPARAWNMSPNAEAAMNEFWDDMMWDTLPTDLPDTSNFVENMEGGEWWQQPTQDWSHWNGNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5B6</accession>
    <name>A0A9Q8P5B6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronic acid decarboxylase 1</fullName>
            <ecNumber evidence="5">4.1.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-glucuronate decarboxylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_03060</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:23917"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="5"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758316.1">
        <property type="nucleotide sequence ID" value="XM_047902208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5B6"/>
    <dbReference type="GeneID" id="71982938"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03060"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000065">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="18">
        <location>
            <begin position="174"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO13950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="60658" checksum="96E8E8B1769AE74B" modified="2023-09-13" version="1">MVAIGSLEESGFRNCTRSSGIITSYQSCPDIVSSLGHPRTSEFARLRHAVRTPDWTKPVYLVKHRVLFRAELTAQGTDQPCCSPDPSMGPPNTPHENRFNATKLSLQCPVAGRAISGPAYPHHAYCKLSVEAQLTHVSHPCLLLRSTVSAHIFVLSSRMSVLNGAAETRQERILVTGGAGFIGSRLVSALLERGKGVIVLDNYWTSFPATLSSVRDNPNFRFVQGDVTSPIPNEIEACQQIYHLACPASPKHFNTEPIRILDTCYLGTRNVLNKAREWKARVLLASTSEVYGQSERDPQDETYFGNVNCFGERSCYDEGKRVAEALAYAYRVEHGSSLEICVARIFNAYGPGMHASDGRVVCSFIGAAIEGRELLITGDGAATRCFQYVDDCVSGLMSLMRSSWEGRPVNIGSEKETTIVDLALLVVKAVSAATGRPQATFKYSDALPDDPVQRRPDCALAREVLGWVPTIELADGVRQTIEWHLGLEVRTGEAPLQCKSTLPDTKDSMFDAVEARRTILGRIDRSTRRRTGAVKRIERHDLCWAQTADEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5J0</accession>
    <name>A0A9Q8P5J0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758541.1">
        <property type="nucleotide sequence ID" value="XM_047901711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5J0"/>
    <dbReference type="GeneID" id="71982441"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02563"/>
    <dbReference type="OMA" id="GVYDKPT"/>
    <dbReference type="OrthoDB" id="4829316at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10872" checksum="C28749CED619A277" modified="2023-09-13" version="1">MSTINPAAAAAATSIEPPAALKGFRAIKDMFKEEHPRARKSISQQPHPVAWKFYQVKLGRAATVYTAGVVLFFGWPFAVKALINLNNGVYDKPTKGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5K4</accession>
    <name>A0A9Q8P5K4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758586.1">
        <property type="nucleotide sequence ID" value="XM_047901952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5K4"/>
    <dbReference type="GeneID" id="71982682"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02804"/>
    <dbReference type="OMA" id="WAITITT"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="51"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="474" mass="52651" checksum="CA44A1F70CEC8231" modified="2023-09-13" version="1">MTSTSLGDLPAATAPASYVQDLTHPPETKHINAGITTSVVGMVVSTLFILLRIYTKAVLAHIFGIGDVALLLAWLISVALQIMVVWLWAVEHIGVHIWNLTISETNLAVLLVSVCSILYIPLMALAKFSLLLFYRKLSLERWLAYDVYGIMTFIVSYSIALGFAFTFACTPLERNWAITITTGHCVNKGALYLATAGLNAATDVTLLILPIPIIAKLHVPLVQKLGLVAMFSIGSLTLITSLVRLSLLPPMVTDLGTTWAISTPAIWICIEANLVIICGCLPILRLFFRHVAPRLIGKHTETAASGPMGSFGKKPIQTPAELSTLDGRERRQDNEHPYGRMTEWDEWEKDMCNDESSEEYIMDANGRIVATKLPRVKEEEEEPQMILRSQSQRPRFMPQRTDSQKSTMLRRNDSQRSKVLPRTRSQRSTATAKSRLSYPTRFSAESAEPGITIPPPTYVIGRDEDGRYSLRSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5X5</accession>
    <name>A0A9Q8P5X5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </location>
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            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="266" mass="30678" checksum="00BF46906C241C14" modified="2023-09-13" version="1">MAAIKDLFLVVTTTTLLFLRIVVSSPVPLAQDGSIPDPPCDPVSTYSPEWFLANVNDDYRRNSSVFENRLLFYTRRCTDDAIRLSCSSDGFYITIWNVWPQSFYNNEHTEPELERCIFSSTTYTQEYYENMSAAFARLARGSATVMHDSADWADPPMDGIFGRIEVPNISEYTDVEELWAINDATSRAAMRGDIYSLPSYHRSLRMAQQRMYKTDMSLRKQGLLSRSEALFEKRAAEDVDWCPGARNWRHERTQPLRHLMDGYDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8P631_PASFU</name>
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        <recommendedName>
            <fullName evidence="11">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
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        <name type="scientific">Passalora fulva</name>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    <comment type="function">
        <text evidence="11">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
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        <text evidence="11">Component of the NDC80 complex.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="124"/>
        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="199" mass="22293" checksum="19C96F1B642BD574" modified="2023-09-13" version="1">MVLFDEDPVDLMSATTSKFRIAPDKDSLNRISESLHTLASARQSRLDQQTDVLSSLSRRLNNIKGQYDYEEERHDAGRHAAEMLKMDTEKFRIAKGVNDAEIETERLGGELAALKQQLETLEKEGVEGGARRSVQKQEDANILKLSFYRSLGIEVQQDAKTGEYNRAVIHNAGKGDVNVIDVDSSQAPGHYTKTLWDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6G3</accession>
    <name>A0A9Q8P6G3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759292.1">
        <property type="nucleotide sequence ID" value="XM_047907555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6G3"/>
    <dbReference type="GeneID" id="71988285"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08407"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="57233" checksum="A1B6C8F26EF70855" modified="2023-09-13" version="1">MNAPILMIKKQVNKLHDKMKAIKSNREDEKKQESAPPPPAYPPPSHPPPVFPQPPNPAPRPLRALLAPPLLPLSRQPPPPTVPDMAPDRVVAPFATRAPHQDHPASRPSYQHNNHKLVTDAMPAPLAFHPFKPQDRGHRPQHRKPLAEIHPNIAPRRGVPQMGTFQIPLDPSISLDSVEQYFSKQPQYDDGGARLGRIPTPDIFKKAAKSAFVRRDMDNMDEVFPDFPSKAAETAVVKIKAEREKKKQESDDWTSVLSMGDLGVTLSAQHESLDQAPVSDIGTLQKLPGELRNTIYRLVAVNPSGSIKIILKTGECDQGKCTHREAPNIVPGLANTCRQLRHEIMPIFCAENKTFHFDHRTVAERCTVGYLSTLGSYIDLIQEYKFDMVRPCWAGVQFLGYATYNFTLTTPAASATGQWALHQDFTMSDELAAAVAAVRPPVTVEVICQCELVKMVAGLNGHNSQYGHGSTKGCGLMALRIASAARWADYVYELKKSKQYMGALRPCKDCNKVKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P715</accession>
    <name>A0A9Q8P715_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760071.1">
        <property type="nucleotide sequence ID" value="XM_047904148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P715"/>
    <dbReference type="GeneID" id="71984878"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05000"/>
    <dbReference type="OMA" id="VAWVGSE"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="76"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="567" mass="62486" checksum="F5D5129C4ADB82E6" modified="2023-09-13" version="1">MATIRSISLGSVSALIVALAIQYAWVHLYVTEYCYTAIRTLSDDQPRANCFKVSTSGLFKQVYSKPVTTITTGIRDGYVLPGLIDGHGHILQYGELLNSVDLFQSKSLDEIRERLKDYIKKSPEEGTASSWIRGTGWDQAAFGGSMPTALDLDQDSQLKGKYIMLDRVDVHCVWVSQAVLDLLPKPLPDHVDGGEIVRQPGLGVFCDNAMDIVQAVYPKPGKEKKTQWIGSAMSSLNSFGIVGVHDAGVAPLDLDLYEEKAKTKEWTVRVYAMLECAVRNTICPEAARKISTTNDMFAVRSVKLFADGALGSWGSAMLEEYSDRPGDVGSLLVNASTLTSLAKSWAAADYQVNIHAIGDRANKYTIDALESALKEVCTEEGLSVSDCQATRRFRIEHAQIIHPDDQARMHSLGIIPSIQPTHATSDMAYAEDRIGKARTKEEAYRMQSLINLQPILGSDFPVEPANPFEGMYAAVNRRSPRTGLGRNGEDEGWHVEETLTTKEALCGFTVNPARGAFLEGKAGVIQDGAFADWIVLDQDIDKSPTEELRNVRVRETWVAGRQVYKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7L4</accession>
    <name>A0A9Q8P7L4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760519.1">
        <property type="nucleotide sequence ID" value="XM_047903046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7L4"/>
    <dbReference type="GeneID" id="71983776"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03898"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="15427" checksum="1B3239613EEC97C4" modified="2023-09-13" version="1">MAKWYERSLVCVAYLDDVPAFDDRGDWQQAVKNTGWFRRGWTLQELLFPYDVIFCDRDWTVLPNLRKWSPMISEITNIPMRCLKPVFSHHDSSVACKMSWAPRRKTTRVEDEAYCLLGLFDVNMPLLYGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7Z4</accession>
    <name>A0A9Q8P7Z4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MFS-type transporter oryC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_05076</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760985.1">
        <property type="nucleotide sequence ID" value="XM_047904224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7Z4"/>
    <dbReference type="GeneID" id="71984954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05076"/>
    <dbReference type="OMA" id="VDRFPRN"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="28"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="518" mass="57159" checksum="3D5ECC1037F58E8E" modified="2023-09-13" version="1">MSFSRFFFASGEEADHSRKRINGYNLWMMLFVSLGSLCYGYTANVISATLAQPTFITYFDLDTRSDATALLSATNGIFQTGGVLGTLTLSWWSDSFGRKGGLAISVLLITISGAILAGSTDIAMFLVFRFFAGAGAFMILTAVPIWMAEVVSPYLRGALVQLHAIMLVLGYNFASWLGYGIYHWKDGGNATWLVPFAVQCVWPLCLLSGLYFVPESPRWLILNGRREEAEKILCKLHDDPADSTNSYAHAEYLQITKQLDVDRTLPSGWLHIFQKTSLRKRALITIGTTGAIQCSGILVINNYGPMLYSNLGFNTETTLLYGAAWLTLALGLNLCVMLLNDHFPRNKFMAIGVLGCMIVLSAEAGIIAQWLGTTNLAAMRAGVAMLFLIELPYDFFLNGMQFIYISEIWPMHLRAKGMSLGVAMTSFMNIVWLQSAPTAMANIGWKYYLAFIIPGTIGAVVMWIYCPDTLGKPLEETAALFGDQDEVAAYMRNIATDDPETGTSGKTEEQTFTIEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P875</accession>
    <name>A0A9Q8P875_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761271.1">
        <property type="nucleotide sequence ID" value="XM_047903949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P875"/>
    <dbReference type="GeneID" id="71984679"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04801"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="32503" checksum="41C406FD0D5F7972" modified="2023-09-13" version="1">MAMSNKKRPYHIFSLPQELEDIIFAYAYDGSDQKKVIVPRKEGADLRHLRAASLPQVNHQQVAPAARAWVESHQISTSGVAPGIIDRDILSGSHGVLHAFATDVKATLWDVHEEENFEEKYPRLRKLTVAVDPSYLGGVFRREQVRRFKKEIPSDLTDDDIRASDAYRRLMALKKVYHLTVVSTRPDLRPSELLATSLQRLERVVRDDLKHRPKKGSTDSTPISTAMPLYLGSEVPCEIQWIELWRIKARRILVRLIACLAVLSMLWACGGFASCWSGFDVEGYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8N7</accession>
    <name>A0A9Q8P8N7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peroxisomal hydratase-dehydrogenase-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_05546</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761674.1">
        <property type="nucleotide sequence ID" value="XM_047904694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8N7"/>
    <dbReference type="GeneID" id="71985424"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05546"/>
    <dbReference type="OMA" id="CDISVER"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000410">
        <property type="entry name" value="Peroxisomal multifunctional beta-oxidation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="12">
        <location>
            <begin position="316"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="761"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO17308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="904" mass="98329" checksum="3EE68593A4EC4846" modified="2023-09-13" version="1">MTQLRYDGQVAVITGAGAGLGRAYARFFAARGARVVVNDLGGTFNARGNDRSSKVADQVVEELVKAGGEAVADYNAVQQGDKIIETAIKNYGRVDILVNNAGILRDITLRKMNDGDWDAIADVHLHGAYKTTRAAWPYFKKQKYGRVVHTTSSSGLFGNFGQSNYAAAKFGLVGLTETLAKEGAKYNIHSNVLTPAAASRLTQTVWPKEMMDLMGPEWVVPLVGYLTHSDCKESGSIFEGGAGHFSKIRWERSKGLLLKPDENLHPEHVLAGWSKITDFTLNEHPQDPADLNAMLSAAERQSPNKPLTTDLGIKGRVALVTGGGAGLGRAYAFQLAKLGAKVMVNDVQNAHAVAEEIKAQGLEAQACDISVERGDVVVKAVIDAFGRIDLVVNNAGILRDKAFANMTDTQWHQVINCHLRGTYKITRAAFPYMVKQKYGRIVNITSTSGIYGNFGQANYSAAKAAVLGFTKSTAREGAKYNVFVNVVAPSAGTDMTRTIWPEAAVQSLKPDYVAPLVAVLLSEKPPANGIIFEAGGGWFASTRWQRARGVDFDFKKGIDALTVEMVAEAFPKIIAFDNKADYPESPADGVTYTSGNAINSGMIKDISQEERTNRKWLSAQQKAMESKSSPSTYSYDERDVILYNLGVGAKRNDLNLVFEGANNFGVLPTFGVIPTYFSKAAWSYKDIVPNFDMRQLLHGEQYLEILQWPIPTEATLTTTPKLIEVVDKGNAAVVRSRNETTDASGKLLFVNEGVTFIRKAGNFGGQKKPSDRGAATADNNPPSRNADRIVEEKTSEDLAAIYRLMGDRNPLHIDPEFSKVGGFETPILHGLASFGITGKHVFQSYGPVKSIKVRFAGVVLPGQTIFTEMWKEGGKVIYRAKVKETGKLCISNAAAELRDEKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8Q7</accession>
    <name>A0A9Q8P8Q7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761856.1">
        <property type="nucleotide sequence ID" value="XM_047905254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8Q7"/>
    <dbReference type="GeneID" id="71985984"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06106"/>
    <dbReference type="OrthoDB" id="3650224at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42339:SF1">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16311" checksum="6D896F0234DAD17C" modified="2023-09-13" version="1">MTPPSSNALQERDHNVSYKDQSTNTLDAAFARETNELLPTSNFTSQNLDAFLRVKGPAAGGHNAGFYAAFVFFEKMRLRDGKDKSKKRQELEKLYQKNHMGAAGFPRESFHKNEGLLCAKGGSWTMDQYGKVHLRRGGTGKVDVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8S5</accession>
    <name>A0A9Q8P8S5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761885.1">
        <property type="nucleotide sequence ID" value="XM_047905444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8S5"/>
    <dbReference type="GeneID" id="71986174"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06296"/>
    <dbReference type="OrthoDB" id="5279008at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="46328" checksum="3AEC426D93D09F00" modified="2023-09-13" version="1">MANATLLSLSLEMLQHIFTFIKPTHLSALRLTCKELEGAVLDQWAACWIADLEGFMFSPARLSRLQSLLLVERFERKIRNVCLTLDVTENSKWEIDLAPSEDTEFLLAQEYIWVGINVGWYNTYLRDLNIDWATIHDVLLLVAEHGSCRLSLDLKGYSDTTSDVKGRFPTITTDMLFVAMKINCLFRSLRITEGFECQSRELGFLSQTLSSYAANSLEHFDFRVEVKDKASMAGKTAAHSFGLSRDILRKATKIRALSIELKTEDYRVIEHPESVKLAREVTSAVQMDLLASLHLSDVQVPLCDMLEMFKLCSRALKDIEINNVWLMAPEDPWLEIARHLRHSFQLESFRVEDLCKIEPEDGKLLDALFSSPWFEPGVCLETWGLKDTTAFLDHIIKHGVTYKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAI1</accession>
    <name>A0A9Q8PAI1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type proton ATPase catalytic subunit A</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_06741</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Vacuole membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763238.1">
        <property type="nucleotide sequence ID" value="XM_047905889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAI1"/>
    <dbReference type="GeneID" id="71986619"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06741"/>
    <dbReference type="OMA" id="CFAKGTE"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00081">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000003">
        <property type="entry name" value="Vacuolar ATP synthase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007868">
        <property type="entry name" value="Hom_end_hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007869">
        <property type="entry name" value="Homing_endonuc_PI-Sce"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05204">
        <property type="entry name" value="Hom_end"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05203">
        <property type="entry name" value="Hom_end_hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0651">Protein splicing</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="17">
        <location>
            <begin position="605"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO18872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1221" mass="134238" checksum="1EADD22E02D78BDB" modified="2023-09-13" version="1">MLGLRPRTPLLRARPSFRDLVASQQTDPTKSRPTTSSSEQRPHSNSNPFSTINSRPFTPPEAAVALPASPELPRTPLPSPITAIEFASIEQEAGPHSIEQQAEEELRTDETAAETPSHTTAKMPPKKQQQNGDEEESQQGSIFSVSGPVIVAEHMTGCAMYELCKVGADQLIGEVIRIDADKATIQVYEETAGVTVGDPVYRTGKPLSVELGPGLMETIYDGIQRPLKGISDVSNSIYIPRGIAVPALDRKRKWKFTPSDKFKKGDHITGGDIFGTVEENSLLSDHKILLPPRARGTITEYPKAGEYTVDTELLEVEFEGKKTKYTMMHQWPVRVPRPTTDKLSSGDPFIVGQRVLDALFPGVQGGTVCIPGAFGCGKTVISQSVSKFSNSDLIVYVGCFSAGTMVMMADGDSRAVENITVNDEVMGKDGTPRKVVGLPSGTETMYEVSVKTQHKNETVSEVSFKCNASHLLVLTTPQYIRQTDHIIRGKHQTSVTYFDWARLEVPSQPRSRSVRLLKLFTRSWDHITHGGAGAAHTKAATFKTTIPAGPFEWTLQAQDHSLLGTHVRKASQQTFCPVFLERNHLSSMLEQSGANASHAGQMAYLLGFWVGDGHYDRAVFSVDPRDSAIREQINAYGGFFGLEVDSREYKKYRYSTAGGSSGTARQPLGTLSGNVTKVEKEGFLGNGDESVSLRPIGFDPEAPTGKRKALNTGNVFWEMVMLTGVRGTDDERKIVPAWLISEPFEVREHFLAGLIESNGHVNQQDLSATVKTIYTTVCHGLVQLARSLGLRASICVEKAKVVRNVSHKTSYAVYISGTPGTGVLESVLSKCALARKTAAVPASVVRDGQKVYFEVAKLPADSYYGITLEDASDHKFLLGNTMVVHNCGERGNEMAEVLMDFPELTIEFDGRREPIMKRTCLIANTSNMPVAAREASIYTGITISEYFRDQGKNVAMMADSTSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKVIALGSPDRKGSISIVGAVSPPGGDFSDPVTSSTLGIVQVFWGLDKKLAQRKHFPSINTSASYSKYTTTLQKYYSENNPEFPQYANRIRELLSASEELDQVVQLVGKSALGDSDKITLDVATLIKEDFLQQNGYSDYDQFCPLWKTSWMMKNMMSYHDEAQKAISQGHNWAKVREATNEIKNDLTSMKFELPTDGEETVTKKYEEILQKMQEKFASVIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAQ5</accession>
    <name>A0A9Q8PAQ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763327.1">
        <property type="nucleotide sequence ID" value="XM_047906839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAQ5"/>
    <dbReference type="GeneID" id="71987569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07691"/>
    <dbReference type="OrthoDB" id="10531064at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="13006" checksum="1B06340BCB791BBB" modified="2023-09-13" version="1">MPSATPLPSARAQSRSGHSRSMTPRFSMLQRQAGRIQKKQKQDLDARDRITKLGGHLLKQAIEKHTIDDICDAFAKMKGPDAQHRHDEVDMIQWMESCPISNGESKRQSKELTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAR9</accession>
    <name>A0A9Q8PAR9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763415.1">
        <property type="nucleotide sequence ID" value="XM_047905772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAR9"/>
    <dbReference type="GeneID" id="71986502"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06624"/>
    <dbReference type="OMA" id="FATERPY"/>
    <dbReference type="OrthoDB" id="3928876at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16015">
        <property type="entry name" value="Promethin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="31077" checksum="03321003719C030D" modified="2023-09-13" version="1">MADQAKDASSGAQEKAQEATKGTPLSGAHEKVKTTTDSILGGLESYGSKISSKVKGMVDYVFPPDKRASFLSKLQAFMLANPKLSAFLGMNLALTGVPLGLFVLFSLTVFIFALVVALVIALLVAVLFTLFAVGIALLFVFPAVLFTTGTACFLFLWGLGGYYILRWANGDKEGPSKQAPEGQSIGDSLNRISGGRLDGFMQNARSQNAKNNETGKNDRPTKQQNNTQTKEHSTSEKQDEFAAGHHAKSAANDSAKHVGTATNQATDAVSGATKPAANASNTAGTIKGGLSGASGLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBC1</accession>
    <name>A0A9Q8PBC1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter G family member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763730.1">
        <property type="nucleotide sequence ID" value="XM_047906288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBC1"/>
    <dbReference type="GeneID" id="71987018"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07140"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="51"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="642" mass="71875" checksum="AFCA83245BF8BD01" modified="2023-09-13" version="1">MHRTSYRSDVEMLIMSPEDPNHFSSDVDHHHVEKRLSGGESYFSNSTVRSIAWQNLTVTVNDRTTGHDRDILHRASGVVKPGEMLALMGPSGSGKTTLLNTLARRTDANAGHVLINGKQYPLCTHRAISSFVEQEDTLIGSLTVDETLKFAAKLALPASVSRAEIRDRVSKLVGSFGLGDQRRTLIGSPLRKGISGGQKRRVSVATQLITGPSVLYLDEPTSGLDSTASYEVMSFISRIALANNLIVIASIHQPSTKTLDLFSKVMLLSKGRPCYFGYTSDVDDYFNEIGMPIPPLTNPAEHMLDITNADFGNDADGARLDAIFTRWKQSQRAQLLDTQLAELFGDDVETPFVPHAAFTSQVVTLLHRAFIKSYRDLVAYWIRLVMYMGLSIMMGTVWLRLTPHQDHIQPFINAIFFGSAFMSFMAVAYVPAFLEDRSMFVKERANGLYGPTAFVISNFLIALPYLFLISILFSIFSYWMINLRPTGGAFFVWVMWLFLDLVAAESLVVLISSLFPNFVVALAFIAFANGLWMSVGGFLVSLPVLNVFWKYVFHYIDYQAYVFQGMMVNEFGSRNYNCEVDNGNCFCMYQSALQSECKIEGIAVLDKFGYPTGRQGKWVGIMIGIIVVYRLFGWAVTWYRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBU7</accession>
    <name>A0A9Q8PBU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zuotin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763926.1">
        <property type="nucleotide sequence ID" value="XM_047909519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBU7"/>
    <dbReference type="GeneID" id="71990249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10371"/>
    <dbReference type="OMA" id="RNHTWSE"/>
    <dbReference type="OrthoDB" id="1690618at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.840">
        <property type="entry name" value="Ribosome-associated complex head domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032003">
        <property type="entry name" value="RAC_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042569">
        <property type="entry name" value="RAC_head_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044634">
        <property type="entry name" value="Zuotin/DnaJC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058871">
        <property type="entry name" value="Zuotin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16717">
        <property type="entry name" value="RAC_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26185">
        <property type="entry name" value="Zuotin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="101"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="293"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="439" mass="50343" checksum="588F397EB86AF144" modified="2023-09-13" version="1">MSSTIQITATLPALPEGWSAEKDFKAVGKLSDVPKRSIEPVGPQFLAHARRRRHKRTFSEDEKIEASKQVVKEADQKDDDIDDVTDPMLLQREAKDWKSQDHYAVLGLGRWRWRATEDQIRRAHRKAVLQHHPDKKAAAGKEENDQFFKCIGRATEVLSDPVKRRQFDSVDEAADVEPPTKKDVQKKPGNFYKLWGKVFESEGRFSKKQPVPKFGNDDSTKEHVEEFYNFFYSFDSWRSFEYLDEDVPDDNESRDQKRHMERKNNNNRKKRKNEDVQRLRQLVDQALAQDERIKKFRQEGNKEKNKKRLEKEAAEKAAKEEVERKKAEEAKAAAEKEAADKAAREESKKGKEAAKNAAKKNKRVIRGAAKDANYFTDGEASPAQIDGALNDTDALILKLDNEEIAALTAKLQGKTDKAEIKSIFQEYAKEKGLATKTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC26</accession>
    <name>A0A9Q8PC26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764165.1">
        <property type="nucleotide sequence ID" value="XM_047909906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC26"/>
    <dbReference type="GeneID" id="71990636"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10758"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="93" mass="9998" checksum="001AD1C5447BF80C" modified="2023-09-13" version="1">MSNTAFRLEAPSAVARPSMPLFMSRVAQLISLLGKHLAIQAGAWGVCSRTSRDQRDPDAISKYGHKVDPIAWGASGPVTLTFPPTSTRNCLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC76</accession>
    <name>A0A9Q8PC76_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764140.1">
        <property type="nucleotide sequence ID" value="XM_047909194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC76"/>
    <dbReference type="GeneID" id="71989924"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10046"/>
    <dbReference type="OMA" id="CTELAYS"/>
    <dbReference type="OrthoDB" id="3647678at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="770"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="848" mass="95193" checksum="5A5A5631A957EEB5" modified="2023-09-13" version="1">MEPLRDTELSPLDPTHSVPAPFDRVKSRYTGIFVEGQEDDLRPLTPGEHHPLHNSHWESERPPFLKTVAIQGFALLWLAPIGTLLYLNWKPHIIGASAWCPFGHCLPRVWDPYISKNEATAYELPAKFDRETHNLLGALQLVAKALEVWFIVIAGWLVYICTTILAGRRQGIPIGYFNRPTEFAEVAGLFDPLLWFTLRRLPSVRDRSRKGRKRVYLFVVTTIFLCFVCNLMGPAVAVLLIPSLQWVQTGAMEHHVYVESGAIEPPNAQGYLFADSQCYESSTDPEEDRIQKNRLTAMFYAHNYSCSWPWSQNLDAWMDSYYAVAPQSYQSAIVSNSIISVQNATSFTFNMTSLPISSNKSAGLDDAASVVWVPSRGVLTNMSNDISMVAYISYGEGSSEMRDEYGLSQAEFDSYAECNNTVQTFLHRDGPILGSVVNAWLGVNNETHWTTMVDEDKWLKCYEGYDITNAPLAWTQGTEGMVSAKYTKCISIGTGWADGYKNASFSISGLYSESLKAYQPELSVFIHSSGKAAFLPEGRLPERVAVECLVKNRRVSDGALCDWDAFWRTGDDPKVRYRSKAVTTIEMLSSDNTLYNDAAQNPDYNRTDYPYNTTLVIDFVAYETFADYMLDPSRLTNSLYTTDYADNLSKTATLDDIKPVMVDPAWVLAAWTADSGAQMLVDDATARVYLLNAFAMILHENSDRATDPVLAQWSRIDAIGMMPIIQMLSMIDFNTTAVAPDAASDAQYPKLARFARIQVYAYGISSRTGWLGVVVTGVGCVVVLLEVVLGFIDRRRLRSLTQLLVAALEHQYTDEFRGVHDEKTISRVPFRLRHDTRNAGRFKFEKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCE5</accession>
    <name>A0A9Q8PCE5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10454</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
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    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="entry name" value="AN11006-like"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
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    </evidence>
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        <source>
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</entry>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="18986" checksum="526AD7D929281E58" modified="2023-09-13" version="1">MQHPQLKSERDCLEKDLLESEKSGSMKGITLKPVPRTRLRQWTATVEITEADYPESAYQGGSFNFTIVIKDEKLTYSFKALEITCNTKLYSPHINAQTGKVISKLDDQYWSPALDLRAMMSAFVESMMQPVPAYAAGEEIGREYKNERIEFTKKAKEWTRLYAME</sequence>
</entry>
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    <accession>A0A9Q8PD88</accession>
    <name>A0A9Q8PD88_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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            <dbReference type="EMBL" id="UJO20323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="475" mass="54107" checksum="26D1C0703460D208" modified="2023-09-13" version="1">MPGYYSRSMAGQLPLTPPDSGSGYGYSSMHYPQDPYSSHQQVSQCRQDSAYDYQQAYMQPPVAPAPPTYQYQQGSYQPTNNLPPISSYYEPLGAPILPPLRIQDRVPFADDYQRRLQEEQQNAVAREQQRQAVKEEKATGGVSAKLDYDMERMTDFVAEAVQSLYAFSQSPVCLADIDVSRSFQHQMQSHPSFRKWVHQVLSATRLPSATILLSLYYLNNRLHYYPKSVIPGENQIYRLLAVSLIMGSKFLDDNTFINRSWSDVTAIKVSELNKLEMNWLSLIGYHLHVDPQESNGLQGWFDSWQDYNANYVAKTQPARLSPLNTDVRSHSSSTRDRFSPYPSPYTGSTASSRSFDAPMTSRSSQYSTPYSATDPWASSTKYQVDDYYRKDRYPSAYELEEASRRASEERARASAYQYAPSTQASYYPTSTYNSGWDQSSWNAHRYDCNCSSCAYQAHYRPYSMASGYTAQTVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDH5</accession>
    <name>A0A9Q8PDH5_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">CLAFUR5_10409</name>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDH5"/>
    <dbReference type="GeneID" id="71990287"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10409"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="15409" checksum="0F06800A7609641B" modified="2023-09-13" version="1">MYDRVKPSFWRTIIGVVSHIEELELYMGRWDLCDQTGKDPVLEAFLKYGHFPNLSKLHLWGEHEKPATVDTRLLKPFLWRHRQMRSVVLKDLLVNDALGPAQLCDGIKCVLVHARETLRTDARFEMHIFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE39</accession>
    <name>A0A9Q8PE39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765192.1">
        <property type="nucleotide sequence ID" value="XM_047910376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE39"/>
    <dbReference type="GeneID" id="71991106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11228"/>
    <dbReference type="OMA" id="MQQIIPR"/>
    <dbReference type="OrthoDB" id="2157103at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="11649" checksum="F1287B9B2029DBD2" modified="2023-09-13" version="1">MLLSKAVRLYRPSARASLPFSRGLATSKDTTSTLASKDDQDLAKKAQDAAESPKTTQSHKTIAEQDRELMEKLAGHSDEGGAAGVEYEDGKPVAQKRSVKNNMFRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEG7</accession>
    <name>A0A9Q8PEG7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Saccharolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11047</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765311.1">
        <property type="nucleotide sequence ID" value="XM_047910195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEG7"/>
    <dbReference type="GeneID" id="71990925"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11047"/>
    <dbReference type="OrthoDB" id="3930412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="44"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="22495" checksum="9317920ACC9D2738" modified="2023-09-13" version="1">MRQAWLSLQHNEKNQRIGADTDYSDVIPPRQLSREQAVLLGANEKHRRVRTSLNELFFATYDILVHSPQSHKDLERTNLATLYNQLRSEVCSIHGVNELDEEGWEYCQGQTVFRAIHGRYDAGYYAYILGGLFAINIFETGFASDRMNVENGRRYRDMVLCKGGSQPEMKTLASYLGHEPASEPYLKWLGIYEAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF96</accession>
    <name>A0A9Q8PF96_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Argonaute linker 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765730.1">
        <property type="nucleotide sequence ID" value="XM_047910442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF96"/>
    <dbReference type="GeneID" id="71991172"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11294"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Argonaute linker 1" evidence="2">
        <location>
            <begin position="480"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="659" mass="71399" checksum="F733A9A824BD2710" modified="2023-09-13" version="1">MAPNKKKSKTLCLRCPKDEELAANNHGANLSKCLKEFPLDRKKNLKVLWPDFSAGDVPPALDFSDEQVCKDLIAEAHALDADARSGATFQGHSINRSMLEAAASKAYPAAEKKNNKGKLPNAPAPSAPVASSSGPAPMVLPIRPAAAPVAAPAPVMASPAPTMPAPAPLPTLAAPSAPAVTTAPFTQVTPGVVGPPTAARFVPANAANVVQVTNTASSVPIIAPADTAEATSVTLKNVTNISPVPYVNKLAHRELETGLSNGRIVIHTKGGAEPNDTQKKPELNKIAHKLGLRTAYAQKGSKGKVLTNHLKFTPPKQIIVYSVEMRRGFNQHNEPIYIKRQWDQKKVIETLSQNDGLWAAQIQANANAWVTDGDLIWSTVPLFHATDPTHVPQPLQGPDPGLQYDNEMGQTLDVERVTVSHNRTVPIAGVDIGELFYDKNAPRFDDSLPGILTRGYNAFLTSHARTLVGPNQNDLTQSGLNRSFENRSVALDPAQRLTVNAMSGYYLSARPGVNSMFININHATSPFFASITVAHCIRRSIDLGRSVKEIKQILKGAKVRIRYGAAIFNSQRPATRHRFIHSVGLPIKSQPPRRTFTSVTNVHAWYTVPHNHPYRRLPEFPTTAVNLDPDDWAINTGKDPTKLPALEEWIPASQLEIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY3</accession>
    <name>A0A9Q8PFY3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Integral membrane bound transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766061.1">
        <property type="nucleotide sequence ID" value="XM_047908144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFY3"/>
    <dbReference type="GeneID" id="71988874"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08996"/>
    <dbReference type="OrthoDB" id="68611at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="830"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="853"/>
            <end position="874"/>
        </location>
    </feature>
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        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
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        <location>
            <begin position="920"/>
            <end position="942"/>
        </location>
    </feature>
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        <location>
            <begin position="799"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
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        </location>
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        <location>
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        </location>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21695.1"/>
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    </evidence>
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        <source>
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        </source>
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    <sequence length="1161" mass="128429" checksum="7627F7D1A9F422B8" modified="2023-09-13" version="1">MKEREDEMANASLNGGAGGATNSPNRFGRKLSLLVRDEAVTDEMQLRRATFILPKTGERSRRQFTLRDASQRLTARSRRASASDDGQEPLFAHGHFGWHDRDRPFATRIWDASRRRALQAWDFALSPTGQGIFKCSIGYVLGSLATLNYTVAGLFGGRQDSKHQVATTVVYFHPARTLGSMHEATIIAFVAFLYAAFLSLCSMGLSIFFAKNDMMAVGHAIVLIFFIGGGFGFMAYVKQKLGNPLVNVGASLASLSSINVLIREGAVQAGAFSMYKVTQQLGMTIMGIAIAAAVNFLVLPTLARKKLSVEMEKNTDLLGEMLISITRAFLHGREGDLEDEYYKILAKEHQASLNAMKKSLNEAKKEHYVLGAEKVYAAEARVVESLHGLAADLGGLRSAAMAQFAFLNQEVPTGGGTSPLPTLSQWIASPPETPAAHEHEPSQYFGNLDVIRESPEERSDPINGTAKQKRTKSASASISRNYSMDFATSTGTATPMSIQSAIELPTPRTRESLVSANIAKSPGDMFIAFISELGPPTKSLVFTVKQILDEMPFKEAAPSRNPWTSRELEVAVNEQFHQSLRQAVDLYRENRKEALGTLYENRAINAAINAQVGSKSTFATRTPTASAPGSPVETRRKPQSPTKSKSLFDRRPEEVLADVEEVTACCGHFSFSLLDFAEDVLHYLDMLDDLKAEMESPKRSWNWLLFWRGYGRQKTPAMRTNTLPESSEDPDVGIPSPIRKADAFAGDLTNAARKQPWYTNFYRSLRFLRRDDVKFGIKVGLGAALFALPAFLRDTRATFLHWRMEWGLVSFMVVCSMTVGAVNTTGFNRIIGTIAGALCAVVAWLISNSHGIANPWLLGFFGWAMSLVGFYIIVAKDNGPMGRFIFLSYNLTALYSYSLSIHDDDNDDEGGIDPAIWEIALHRVTAVAVGSIWGIIVCRWIAPISARHKLREGLSLLWLRMGLIWKRDPLALFLLGEPTSAYMDIREEADLQAFLGSLKSLRKAASLEFEFQGPFPDKPVGRMLDCASRMMDAFHAMNVVISKNPQCTPGEAAVLRYTRPERFALSARISHLFTVLASSINLEYPLSDALPDITDRRDKLLAKISEVRRTGEGRDLATEQDYEMLYAYVLVTGQLAQDIQAVGKEIEVLYGTLNEENLRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGS8</accession>
    <name>A0A9Q8PGS8_PASFU</name>
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        <name type="synonym">Cladosporium fulvum</name>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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    </dbReference>
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        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
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    <dbReference type="PANTHER" id="PTHR37017:SF13">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="UJO22349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="293" mass="32275" checksum="8B5DAC4787804FFD" modified="2023-09-13" version="1">MPSLKLLKSLLPTSCFPRLRLHSKNTKSPPPPCTPSTTIILSHGAFNTPWHYNLYTHALQKDSFRTLCPQQSSSGPSPPPNSFESDIELLNETVRTELIAGRDVLLVCHSYGGIPGCEALADLDLPEKGVDGDGQRIGKVLGIVFVSAFVAEAGQSLVTSKMAGRASWVRVEGPLSHVTNPGPTLFNCVPNATLRQQFVDRLVPQASASFITPTKHETWKDHPCYYIRCLHDQAMFPEEQDYFIRRLQEGNSSAMVQELPSDHAPFASMPERMAEVTGEIVGELRGGIVERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGZ8</accession>
    <name>A0A9Q8PGZ8_PASFU</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71988890"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09012"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10874" checksum="6DE5E4984BE5B0F1" modified="2023-09-13" version="1">MAEQDGPFTWLTSLQTWPTRLAIWINFPLSSLCWFAGMTQFFAPYTDWLPGITVLLIWYLSNMPVIWLALHYEFRMQGSRRGRATSREAEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH00</accession>
    <name>A0A9Q8PH00_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PH00"/>
    <dbReference type="GeneID" id="71989427"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="12785" checksum="79CD0DB5CB27B7B9" modified="2023-09-13" version="1">MKGISYPQIPPTISRSHTQQDQQENMKPDPGSTSTTIPPHHDLEGLRQQILANAVVTFSRIYQKTPACEKYIAQRHDFEVIVEVDGPGDDPPAADTYRALLVYRKCGGHKQTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH54</accession>
    <name>A0A9Q8PH54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766925.1">
        <property type="nucleotide sequence ID" value="XM_047911354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH54"/>
    <dbReference type="GeneID" id="71992084"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12206"/>
    <dbReference type="OMA" id="NTGMHGE"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="68" mass="7710" checksum="7BFE771DA44E08BA" modified="2023-09-13" version="1">MDSAKVPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDTTRSIIRNVKGPVREDDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI22</accession>
    <name>A0A9Q8PI22_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12152</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767183.1">
        <property type="nucleotide sequence ID" value="XM_047911300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI22"/>
    <dbReference type="GeneID" id="71992030"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12152"/>
    <dbReference type="OMA" id="YKPSPAC"/>
    <dbReference type="OrthoDB" id="5422384at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="981" mass="107867" checksum="ABDEFB025B0ED91D" modified="2023-09-13" version="1">MFAGPGTPKARSIRTAPSTTPVVPVPSYLLDTVQSNTPSGPPPGGRSAFNSSYNPGKKNAGYGVPDESEYYEDEDEDVEAEDDDLFGRQSLLSSRGPAHSLRSSIGASQSRGIKRDRGGQPKETLEKKHGPVMRFNTRGKKAAQLKEPDHVILESERIVDDVNARIQRQPGQRDALLADAASQLTKLWSKASKSATKPGGIGPESSDGLTKANYLASLLLQLYYPHSTKATPATRNPRSLTTTEQAPTAVPVPKALLEWLETYHVPFPDDYDYVRDYNPAPSAQESFWDVVLANILRGKLGRAVGLLKDAGWEHAYTAEEDHAYEGYNDQQLEYIDEAVDDCVRVLEACPGHKYDDWDVRSLDWTTYRQRANAMFEKLVVLAEGDGEQEGNMFERSVRGGGQSLSSSVRKAESKVPYTIYDNLKVVYGILLGCTEEILMTAQDWLEGSLYLTIWWDGTSEEDMGASLSRSSMRRSAIQSDRLVDGFPLDAYRRRLARAFDDITKDVEEPNKNEKKDPVFEVDTLDSIQLGLGCVLEGSVTEAVELLRTWSMPITVSVAELGTLGRWIPCARPRSRGGFEFSRDNLLGMSAPGAPPPDDLDLDELLSEYADLLSAKREVDAKEGWELSVAVLNRLDQAPAAEDRIGDLLQRLDLAEEARVGKVLQVCDELGQVEQRRQIAERFADSLDEQGVQAAGTILTYYARAQADTKLKERISTLTASCLAQSAAFPPQNELDETLAALISKDRPAMKALAKVDLEAATLLSSQLSGYATLRKYYDLRDQEIYTSQGIPVDHPLRSLERRRAAASALFAIITSAADCISGGLYDPEVESVIPADGILTLLGEALPLLGQQLRIFTEQHVYTLLAIVEAFHASPSRIQENADSLLATTLDLYKEETSTASGVFKKKKSKTDLSASSSWDMIGSVMAQSQSGKGVKTERAWDWRRGLVGSGEDVDRALVVRLVREGLVKEVAGGWGGRLNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIB9</accession>
    <name>A0A9Q8PIB9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-threonine protein kinase 19-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STK19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767540.1">
        <property type="nucleotide sequence ID" value="XM_047911485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIB9"/>
    <dbReference type="GeneID" id="71992215"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12337"/>
    <dbReference type="OMA" id="MNFRWAL"/>
    <dbReference type="OrthoDB" id="3980126at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046579">
        <property type="term" value="P:positive regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018865">
        <property type="entry name" value="STK19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10494">
        <property type="entry name" value="Stk19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41399" checksum="40F9F7DA2B3D1557" modified="2023-09-13" version="1">MPKTVNPLLRRKSSSPFTTAQRTKPGSRKSSLKDDATERLDDVGGRRPSLASANTPQDVVKLIRYIRDASFEDVPDRAAGMNSEQISATLRFRASLPPVVSVAHLHALSVSTTNTERELARLIAMGKIRKVIIPGRGKGGSAVGEGVAVVEDWESRLQEESALEDEVKHKYMALMATHPASPTAPVTSLTDAEVRSLVTAGYLTNPAAITSSLSDLFARPSGAPSGSISQAGFKSATGSLAAVGGYGAIQDSGGGGSMLATKDTRPSNLKAQREMTFSLPNTGAYLKLLTEARLHLLFLLKQLSPRYKEATKAFLEEKWNGNVPNDAISQQKRMRGEWSGVLPGKTKRWREFYGVEFEWVLAECVGSGLVELFETGSVGVGVRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIY0</accession>
    <name>A0A9Q8PIY0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_11965</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of pre-60S ribosomal complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767647.1">
        <property type="nucleotide sequence ID" value="XM_047911113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIY0"/>
    <dbReference type="GeneID" id="71991843"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11965"/>
    <dbReference type="OMA" id="AYKEHEC"/>
    <dbReference type="OrthoDB" id="7396459at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17960">
        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056330">
        <property type="entry name" value="CTT_SPB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23681">
        <property type="entry name" value="CTT_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 16 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="45"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="292"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="553"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="569"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO23281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="641" mass="72339" checksum="F99B246CEA5276E6" modified="2023-09-13" version="1">MANDSTEKKQPKSFEALTPELSQWILDFTHGMGFARTTPVQAMAIPLLTGNKDLVVEAVTGSGKTLSFLIPLVERILKSEEPNKKGHVRSIVVAPTKELATQIYDVLRGLLDFHPPSSAVLTESSQEPVDSDDEEMEDVEKPVIPPGPYAIPQLLVGGRTKLGEDIATFSSLNPNILIGTPRRLVEVLQSSKVQLKRHWFDLLVLDEADRLLDPNFQPDLQRILDLVPKERRTGLFSASVSEAVDELVRVGMRYPFKISAKVRSKSGALDKRTPESLKLYHIATKPSLKIPYLKSILETNQAEKSIVYVSTRAGVDYWSQMLPALLGILVFPIHGDHKSAIRIKNLQRFRDSSKPAILLTTDVLARGIDIPDIDVVVQLDPPKQPKDFIHRCGRSGRAGKRGMAITFLNEGNEEDYVKYLAMQGTPLEPYPSLAQLSEQDVNDSIEEMRKVLVQKRELHDRSQKAFVSWVQAYSKTLPSDIFSIRKIDWPEVGKSWGLLRWPKMPELKRHCPEAREDRSFGLDLPQDFDLNNVAYADKVREARRKEIMEAFSRGEKPDLPKKSGGALADMRRRKESAWSNQKDAKAVKESRREKKEVRRKAESKAKMSDADEVKALELDQLIAKVRAKNQQGEEIFEGFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKZ7</accession>
    <name>A0A9Q8PKZ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768716.1">
        <property type="nucleotide sequence ID" value="XM_047913113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKZ7"/>
    <dbReference type="GeneID" id="71993843"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13965"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="28182" checksum="7EBF98F2B38F32E0" modified="2023-09-13" version="1">MENDSQVPLAPKQPPNALIHFEKDARRFDSVEVGQNSQITMVPELEGNVLRAYLTIQYRNVKCVYLLEHKDGEVEVIGGPLHHKTAFYKKFSKIDQRRVKFREDLHRSGSNGKASKWSFLCLTFKKVPRDSVAKHFSGEEFTIACIISSAQVAKIFDDCVLIANGKTCLRAPMKRVNEVTHEDASSDVSNKKRRIPESSANDADGDNDSGVDLPPSEPDLEAMRAQIEDGVRARLEQELEAKYKIQVSPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL38</accession>
    <name>A0A9Q8PL38_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768745.1">
        <property type="nucleotide sequence ID" value="XM_047913167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL38"/>
    <dbReference type="GeneID" id="71993897"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14019"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="333" mass="37765" checksum="55DA5121862B53D9" modified="2023-09-13" version="1">MPIQQGPPNMPLVTQSQTTPHEDDLSALPISVPTTMMPKPNKSATAVFAIPELLEMILVLLPAHDILRAQAVSRTFRDTITGSKQLQRLLFLEPSGAPPHIHASTEDINTLLLEKAVSLPAFQLRTLYPEPVFNSKLSIPQLDFTSGLDLAVSVSSYYVYIFCDIRREFQWQTLLDGYTSSSKDAAWRRMLVRQQPILEIQVILRSAGGHCQSRMTFPPTTTFGSIIDWMEAEHLAWQGTSGVVFSTTRRVSYLLNEDKVNELLEIIKNKNGPLAYTACQILRQMVRKIHQESFDQHQGSWKGRLYSNEDHECIWRARRDLEAALDSSEMNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLJ6</accession>
    <name>A0A9Q8PLJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769016.1">
        <property type="nucleotide sequence ID" value="XM_047912600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLJ6"/>
    <dbReference type="GeneID" id="71993330"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13452"/>
    <dbReference type="OrthoDB" id="3648898at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="21495" checksum="1CC1CE93B220DF1D" modified="2023-09-13" version="1">MSVRLVEPSLVRARSVASRGRPAFLDRIEDDRFSRVRSHSQSLVHVDHKGRTLRDIDEEIRALEAQREREREAEIYERKAFRDEQRAAEEYRLASRLREPPLHDAYELRERSRSRFRANDVDVYDNSLTRRSGSCHRDELVVYDRYGHPTYYKKEKSPPRNVVRVEKDRKGRMSLVRSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLM8</accession>
    <name>A0A9Q8PLM8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769061.1">
        <property type="nucleotide sequence ID" value="XM_047912543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLM8"/>
    <dbReference type="GeneID" id="71993273"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13395"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016636">
        <property type="entry name" value="3-oxo-5-alpha-steroid_4-DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015596">
        <property type="entry name" value="5_alpha-SR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="124"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO24695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="33704" checksum="F84BBB18FB97586E" modified="2023-09-13" version="1">MPALELIPGFLPPSREQWELLSYAWQFFPIFTAIQWLTDYYPQGKTSTTSRFNLPGKWAWFLMESPGFLTVLYCMFAIPERENLIGLPWANWTMAGMFTIHYLYRAILSPLVLNPSMSPIHPLVFVCAFAWQVMNGLSIGGWLGGYGPRTVWDWQDRSREIMVGMVIWGWALLGNMFHDDDLREIRRAAARRQKQQAEKEKKPQDGIEKLYMMPKNGLFHYILFPHYLCEWIEWGGFWLVGGLNCVPARSFLINEISTMLPRALAGKRWYVEKFGKERVGNRKAVIPGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLM9</accession>
    <name>A0A9Q8PLM9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769176.1">
        <property type="nucleotide sequence ID" value="XM_047912794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLM9"/>
    <dbReference type="GeneID" id="71993524"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13646"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="20656" checksum="34466A0C3E2A8978" modified="2023-09-13" version="1">MGYNALLAGPTLPKNAVQPIKLDLNLGGGQCDLKGLNTAFQAIKDSVDKNTTTLNKAISDKAEISGLREQILVLFPMLNLGNALGQDRDHQLIAKLYLVLIGSTTKVHAQALCDEEQLRNAVAAAKKKLIIRGPDAVSTHDALMGLLAMTAAMLEQHETRNFDVCDASEVTYEEGGSAYHCWKRDEAGNVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQQ7</accession>
    <name>A0A9Q8UQQ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763292.1">
        <property type="nucleotide sequence ID" value="XM_047906598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQQ7"/>
    <dbReference type="GeneID" id="71987328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07450"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="22746" checksum="C0EA4CC667569C69" modified="2023-09-13" version="1">MKIQNSLTALVAASTFAQAMRFPMHNVRDVEGLEGGGNPPPPHLADGGPGPKHLDDDEHRDDIDRNGDGNTLPAHLEDDEHRDDDEHRENDVDRNGDGDTLPEHLEDDEKMAKIKTGMATTCQAISKTETLLCHRTTPTAKQASNRTISTILHMPVSLKSTAIRNGDGNDNNDDGPDGDGDGDGPDGYRNAAGANTFPMLGGLAGVSVAVLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URN0</accession>
    <name>A0A9Q8URN0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Stergiopoulos I."/>
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    </evidence>
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</entry>
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            <dbReference type="EMBL" id="UJO22405.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="87" mass="9308" checksum="41E1F39564F6EDBF" modified="2023-09-13" version="1">MTSNIITIDTALSATSYHAAAAAASSASELVHISGQPGTNINGEVPDDYISQIELALLNLRKVILISGCKVEVILSLRFYIVGFWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUJ8</accession>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <location>
            <begin position="118"/>
            <end position="156"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="43944" checksum="8802B9966B787D3F" modified="2023-09-13" version="1">MVPRYYHDTQIMHGNNDNVSPRYLITRAQKDQIATQISIGTHRICSDHQIGLLSFFANDGTILDDKHSIEAIHVRSFSDQFIESLPASRSLVGALPSKDVFLAAHLTPMNIHVDDAICLICWQPPTSPVQTQCKHLYCAQCLIAWFKITDTCPYDRRVLFEAESASTTQPMTLPNEGLLQAMTWPQGLEPFTIADTEDEKSPFATDADLEVVDDRILAIRAAVVHLTKHFDDWFRVGTGENEYLHDHDADSPVDTDPTILRQIALAGCQRLASSPGHHPVMHAMCRYEWTRIYRRISKLLEHKEIRPAKVSVLKNVLVSLLKPFKYDRGLTTRSPGIVLNREVRRFGEDVRVLIRWIASTAANQRMQLTAEVPAGLAQQMLILASKIHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUN4</accession>
    <name>A0A9Q8UUN4_PASFU</name>
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        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_12316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992194"/>
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    <dbReference type="OrthoDB" id="3643498at2759"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31438" checksum="CC7C320340E0C1B4" modified="2023-09-13" version="1">MATQANTSPQVQQDDHKPTKTAQAHSPLQGQQDNSTPTRTDEPEKSSLSAAQRVFGIFELAEAIFLEMPPRDILLDQRVSRTWQSTIIESTPLQQATFNKPIPSQWYTFGGNEIAGEEHSMYQRSFFHHPLLDTVVDGHFHKSTAEKKREILTRPEASWTRQLLTQPPISGCVLLVERLRDYRTYEKEFHLSDQDGVRLGIAAQKSWGNSSRWVWISGWEQWYSAEWESRSARELLAMMKGEAWWRAWVEREMYRCSDLCEALVRCLVPVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUR8</accession>
    <name>A0A9Q8UUR8_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">SPRY domain-containing protein</fullName>
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        <name evidence="7" type="ORF">CLAFUR5_11907</name>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
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    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
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        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
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        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="288"/>
            <end position="442"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="41"/>
        </location>
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        <location>
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            <end position="59"/>
        </location>
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        <location>
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        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00449"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO23183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="449" mass="48910" checksum="3F5AAE47E27DD0F0" modified="2023-09-13" version="1">MGDKYQAPPGPPPNYRSQSTTEVQKAQDQDGRQSTQPQPGSWTVGGGSSSRQPEMSSNKPFREPRMSATSGQRPASLNVQAGQTCQSPPSSHPSSRPSSHQVSPQGPPSNATSDVEMSEDEEFQYQPPPGPPPGRASKQPDMDYSPPPGPPPGHGSTQTGHDAPPEYDPWVGDDGGLRPPPAFSAVRPENQRSPAANADFDDAARAHAWCRDNTLWNAVEHDGSIIERIQVGDMRLTFPPNTMDITNYQPGIGRSYIRTTATIGDTILLSDIPAYASHRQNPLATGRSHTVYFELHVQSLGDRYNPNNNIESGVAIGFVAPAYPAWRLPGWHRGSLGVHSDDGRRYVDNSYGGNDFVAPFKKGDVVGIGMTFAPPRHGDRNNPCQVFFTRNGKHEGAWDLHEERDRDADEGDVAGLEGDHDLLAAVGVFGSVELEAVFHREDWLYKPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUY7</accession>
    <name>A0A9Q8UUY7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12843</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
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        <property type="protein sequence ID" value="UJO23454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUY7"/>
    <dbReference type="GeneID" id="71992721"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12843"/>
    <dbReference type="OMA" id="AWGSIYR"/>
    <dbReference type="OrthoDB" id="10251136at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000093">
        <property type="entry name" value="Fidgetin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="607"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="474"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="858" mass="93004" checksum="F32656DE481BA747" modified="2023-09-13" version="1">MMRKTPSSAMQKTYDECYLICSTAIYFEGQNNEAEALRAWRNALDQIYYHNAYKMPSNYAPRSETEKALQDSLRAMELQCKERVDLLEALRKSRLEAAEEAKAAAGGDISTGPNVLSKSRESLASIQQSSSNGQSSTPGWLGNDTIPQATYASIPKPQAFTERRPAQPPRPSYNTTKSSADDMPRTRSLQPGLSSNLTTPVGDSSRARTPSPEKKGGMLKTLRAGNKDRASSGGKMASSMRSRPPPAAASAASLSWSGRPPRPSLPQNGSSNLATSSAATATSWDPYTRSLVERPKQDNAMAPDRRASDNAFVRPPSPSDYVQQHSTSDHEGLNKTRSYPPPYPEYPTMNPYAQAAFNHSNSSVDTAKAPPPPPHSAPPTSNQSQAPPATLASMGGPTSISYMKEYPSSPARTKRAPPPVPGKPSGRNSDSDGPSRSAAGKTVPARTSPKLAIQRKAVGGRVAGVVNAMAERQRLDNTIPPTSKNHLPSSGAGGASRRPSAKRKIESKPVPARAMTPPTTDDSPDSDYAESPSEEQVWEQRVKKVMKNLPKGVDEAAAKQIFNEIVIQGDEVHWDDVAGLDIAKSALKETVVYPFLRPDLFMGLREPARGMLLFGPPGTGKTMLARAVATESKSVFFAISASSLTSKFLGESEKLVRALFALAKELAPSIIFVDEIDSLLGSRGGSSEHEATRRIKTEFLIGWSDLQKAAAGRESTTGDASRVLVLAATNLPWAIDEAARRRFVRRQYIPLPEDFVREQQLRTLLAAQRHSLKDRDMKVLVQLTDGFSGSDITALAKDAAMGPLRSLGERLLHMSPDDIRPIQMKDFEASLVNIRPSVSKQGLKEFEDWAREFGERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVB7</accession>
    <name>A0A9Q8UVB7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">AMSH-like protease sst2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12668</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768106.1">
        <property type="nucleotide sequence ID" value="XM_047911816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVB7"/>
    <dbReference type="GeneID" id="71992546"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12668"/>
    <dbReference type="OMA" id="SWGVFRL"/>
    <dbReference type="OrthoDB" id="3640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061578">
        <property type="term" value="F:K63-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070536">
        <property type="term" value="P:protein K63-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08066">
        <property type="entry name" value="MPN_AMSH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000033">
        <property type="entry name" value="AMSH-like protease sst2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044098">
        <property type="entry name" value="STAMBP/STALP-like_MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015063">
        <property type="entry name" value="USP8_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947">
        <property type="entry name" value="AMSH-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947:SF13">
        <property type="entry name" value="FI19924P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08969">
        <property type="entry name" value="USP8_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140856">
        <property type="entry name" value="USP8 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="352"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="290"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="529" mass="60131" checksum="198846A272882175" modified="2023-09-13" version="1">MALSRHHAAFSKPRTVEEIVREAQNFDFNTGRSMQQWLRSAKMLLTEASICEEEGNYQTAYLYIYRHCELVLQKLPEHPDYRDPRYKHELAHARKAVQKGLVKLEQWKPRITQNYQRYVKAMERRNAERQRAQKEFNQGTSQYPSYNDSRRGSRQSLDSAPPSPTQTVSVLNDRNFAVELAHREIRRRDATRTSTKQAGISPGTVASRRQGIVGREYGDEGYDKNGVREAASHLERPTTQDRDEPRAWRRPHSSYFYPSVPLKEERIDWNRPPPVAPESRHALPPARPAKEALYDQQTSELASGPPRVPPRPRYDSPTMSASDRSFEQQPQLPSKYTFEPSAYTEAGEPLRTVILPPALRNAFLNLAHPNTARNMETCGILGATVISNALFITHLIVPDQTSTSDTCDTTEAGDNALFDYCDSKNLLVCGWIHTHPSQSCFLSSRDLHTSSGYQVMLPEAIAIVCAPRHMPDWGVFRLTDPPGLPHVLDCKQSGLFHPHTENNLYTDALRPGHVMEGPLEFEVVDLRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVN6</accession>
    <name>A0A9Q8UVN6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calcofluor white hypersensitive protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768466.1">
        <property type="nucleotide sequence ID" value="XM_047912200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVN6"/>
    <dbReference type="GeneID" id="71992930"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13052"/>
    <dbReference type="OMA" id="CVWYFPL"/>
    <dbReference type="OrthoDB" id="68581at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000031">
        <property type="entry name" value="Calcofluor white hypersensitive protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="650"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="278"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="452"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="683"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="949" mass="106270" checksum="1A3B2750426C9C8B" modified="2023-09-13" version="1">MPPKHRDGDVVAVIPGQFISHAHTISAYAAFLSALIVGMWLHYHKIVENEHFGYPIEWFPSVSATIGDRYPERSFFQVFIAICSGPRFALVFLWYCLANKPGSTLPKFVAGVGVFRTLTCGGWTYVTSTDDHDWHDIFMISYLVATLPWTLGCLALSPPNPQAIKYRKYLGGAFFGTLVPLIYFFIQHKVHKVPGAYTIYAFFEWSLVLLDVGFDAITALDFSTFDLVVKDTKGLSRGEKRVDRVLEKNKDKAIGQVFDDKFSTDEMLDAAADVYLGYTFWTILTSLGVVVWYFPLWHMGISGYEVAVMSTISPLLLGVPPIRRMALKSVPTILLTTIVGLLAYLIKSPELRLGAVSFAVWQGCLGWVAAWYSKRNSPAMLEARVSAWLIGLIASSISKFAFWTNNPLWPIMNEANGGLNKTGLFLFVLALLRAFQKQSKHIDSAPIEKPKGPSIFAGLGLAGAIFGLHSLLSDSSTMILWVWEGYPVRGPLAVPHGAVTILAMGVGLLAGLWYPNVVRSWAAFGIGSIGAAVLTTFSNWTGYYGGLALAVYLVAITPVLISNAVRFAPGRTFFVAFFFYNFLVLFHVWVVAYAFVPGGPLVREHTDWVMATTMVMIGCGVFSTIQNSTPVRQKSFQPIQSPAARRQRSYYIYILLALQLLSASVAYLRFPSYDYTPYHQDSKLITAGIWTIHFSIDNDMWSSERRMESLIRESELDVVGLLESDLQRIIMGNRDTTQYLAEELGMYVDFGPGPNKHTWGSALLSKFPIVNSTHHLLPSPVGELAPAIHATIDAYGELVDIFVFHSGQEEDPEDRRLQSEYLANLMGSSPRPSILLSYLVTRPNEGNYNTYVSERSGMKDIDPTDWDRWCEYILYKGMKRTGYARLSRGTITDTELQVGKFRVGAPEDTSNRMVHENEVPFDMRFPTLFRGQGVRGHRYHVFDEPRYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY2</accession>
    <name>A0A9Q8UVY2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_13575</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768809.1">
        <property type="nucleotide sequence ID" value="XM_047912723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY2"/>
    <dbReference type="GeneID" id="71993453"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13575"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02877">
        <property type="entry name" value="GH18_hevamine_XipI_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045321">
        <property type="entry name" value="Cts1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="3" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="30"/>
            <end position="344"/>
        </location>
    </feature>
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        <location>
            <begin position="346"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO24443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="377" mass="41213" checksum="0C305E2BC924547C" modified="2023-09-13" version="1">MNFTQSLGARASAAVLYAHHAAAQRFSNAQNLAVYWGQNSYGAASGGLEQMNISTYCQNANIDIIPMGFVVNITTSPGGQPQINFANQGYQCGIFPGTNLWNCPTYTAEINQCQQAYGKTILLSIGGATYHERGFPSKAAAEAYAQLIWNTFGPVNSSSNALRPFGSAVVDGFDLDLEDGNNYFRAFGLKLRALMNANNSKRFYLTAAPQCPYPDANLNPLLNDPNGAVPFDALFVQYYNNVGCDLRAYNIAAGATQRNFNFQTWSNYAKSSASANKNCKVFLGVPGNIGGAQSGSYRTAAQLKPIINYCKSFSNFGGVMVWDASQAYANKPFLADLKTSLKAARTRRRHEGGERHGHGHGRRHWNVERVVKREQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWH9</accession>
    <name>A0A9Q8UWH9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769293.1">
        <property type="nucleotide sequence ID" value="XM_047913714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWH9"/>
    <dbReference type="GeneID" id="71994444"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14566"/>
    <dbReference type="OMA" id="LWIFSWP"/>
    <dbReference type="OrthoDB" id="203796at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="433" mass="49609" checksum="07D6F9783B84072B" modified="2023-09-13" version="1">MASNTLDPKRAAAALPVSPAVSYRDDPDALSMHTTRGGYEYDDAPEFDDVPQLPSYDESVTAEGSSDDRAAPQPVDEYQIITAPKTNRNWGTKHTHSPHKAVGSETSIRMDERLLESKELYEYIENYLRMIPPRPMIRIQGWHWQKTKKRDKTETERIYDFNIVLNMQSLLPSSRDKGWVTAHTADNSDKVYRGSFRKTRAPGYRQDIEVGEEGTPDLREWCKRFAECKAALKIFRVERSVVGMNTDLIKEELEPLIRSTHYRGHIDITFPTADQNVDIYTPHWLNSARLSWVRWIFYLTFLWIFTWPVLFFMTKRWDVYNVQWSFSKIFTIDAEGRQEKRYAVMSERAWINRHADLVRSLVLDRFHGDGTDMPVNVDVDVEGSGRGARGQVPRTGNGSVDAAVGFIQGGVGAWNAFNGRAQREGWGADESGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWJ1</accession>
    <name>A0A9Q8UWJ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP synthase subunit J, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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</entry>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="613" mass="65307" checksum="2EBB28D1E8245AF8" modified="2023-09-13" version="1">MSRDGAKGRPNARLKTSELVPTERTTLLPSTPPAAASEVANADDNDARTAPRFVAKAGSLSSSGSINSMAEDDEHTKANQSIGFGRAVCSTIALGTLVFLIATNMSMLTTIQSAIASELDAFDSTPWFTSSFLICTSALGPLNGKLSAVFTPRLCIVASSIIIAIGEVITAFATSLESFLVGRSVAGVGASGVFTISIIIVLELTGSKRKGLAIGLLNSGYTFGVAVGATGAGFFLPIIGWRALFWIQAPIALLAGLMLFFALPFDFTSGKKDTSDHSTWKRVRRIDYLGAITLTTSLVLMLYALSSPKSIPILPLILSVVVATAFVLVEAYLAYDPIIPVALLRHRGLLFTCLGTVGYMMSRWCVLFYAPTYAIAVRQWPPSVGGAMLIPTNAGFATGGLLAGWLHIRRKGSFWTPTVVSYAIFPVTLLVLGMLSHRNGSPVGFIIVLFINGCSAGAALNYSLAHVLHLTPKEGHYIATALNATFRGFAGSFGSAVGGGLFTRTLAASLASQFAERGMKRDDLVRRLLGSPALVDQLHGIEREVAVKGYEDGLQTLWYGAALLAFAMVFVQAGTGWKGHEEKCKEAIIAEKESRALLEEREHRDREDPEEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5B8</accession>
    <name>A0A9Q8L5B8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_00712</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755448.1">
        <property type="nucleotide sequence ID" value="XM_047899860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5B8"/>
    <dbReference type="GeneID" id="71980590"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00712"/>
    <dbReference type="OMA" id="MVDIMKF"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030447">
        <property type="term" value="P:filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000385">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIB" evidence="16">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="666"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="278"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="400"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="534"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="577"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="695"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO11082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="946" mass="103271" checksum="8EEA24157647DCDE" modified="2023-09-13" version="1">MKDLAVPELHPTTSTPTSTAAGDHHTARNKLRKRSPRRPAPPGRFHTNSSTTTAAAAAASGQQKPRSVSANNSSSNSNSNNTSPRRAAGGAEVAATTSTGAARTLQRSSSSRRHAQQKHSPSPMLPSPSSSNSNSNRNQLASDVDNAPASSNRNSLHPPSYTYHHQHAHTPQPARWSITHQTSSDLLGQRFDSADILNNLNAVSYSADYTTDYTTAAGAASTTRQAPAYDPFAPTVTQPRPEPPQLHVAPPTETQSYGNSAAIANPAVRLSQSLAATGRRMDDLASPRGDMSGMRSPRQRYSDESGKEGKVLKKKSGFSNIISSLVGTPRKPTISAPENPVHVTHVGYDQETGEFTGLPKEWQRTLQANGITEQEQKKNPQAIIDVVTFFNENNDNGSDDWTYHKFDNAKPRDCPQSLAPQGYPQQGPSPGGYGQIMSPPASPRFPKNEGESFENPRAPPPVPRGQGLGLSSPISPPAANGNMLPMRPAPKPPGGHSATMVPQRAAPPVPSPQREQPRNENGLPAVRYAPPTVTDISSNTQPMQSRSRANTGPAYQAQSPVSSPQEYQRQQEEAMKHAQQAMKQQSLERSQSQRQPNNVYQQQQAVPQQQLPSPSDSRQIPHPAAVDPRLGPAPRPRQRPRQSITNAEVLSKLQHICNSSDPTKKYRNLIKIGQGASGGVYTAFEVGTNKCVAIKQMNLEQQPKKDLIINEILVMRDSKHKNVVNFMDSFLVKGDLWVVMEYMEGGSLTDVVTFNMMSEGQISAVCRETLHGLQFLHSKGVIHRDIKSDNILLSMEGSIKLTDFGFCAQINESYMKRTTMVGTPYWMAPEVVTRKEYGRKIDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPAIKEEHNLTPLFRDFLSFALKVDPDKRASAHDLLKHGFIQTAEPLATLAPLVKAARLARAEERKNKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5E6</accession>
    <name>A0A9Q8L5E6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755533.1">
        <property type="nucleotide sequence ID" value="XM_047899742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5E6"/>
    <dbReference type="GeneID" id="71980472"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00594"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="112" mass="12784" checksum="4FE023D036EEADC7" modified="2023-09-13" version="1">MQKPSKSQAKKKKRIASAIQFFDEQYGKDVDRLAGWQALCADVGVPSLEDVFVNIIDLVKAKRAGNAIHRFDNLKELQDYSHHTRKKFPLDEAKEKKMLEGSLVKMSGPRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L658</accession>
    <name>A0A9Q8L658_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC multidrug transporter atrF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00704</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755905.1">
        <property type="nucleotide sequence ID" value="XM_047899852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L658"/>
    <dbReference type="GeneID" id="71980582"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00704"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002416">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="604"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="675"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="845"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="255"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="890"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="901"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1005" mass="110781" checksum="D356DF1D5DC278A6" modified="2023-09-13" version="1">MTRPSKRPAIPDGEIEGDWPRSTSFIGHQSAQEVADRAITTPSSGDNASQRISTTGITTGSRLDDGKSKVVGPADELERKSGRAEHAPNVPSIATARLASSSNDERREQHVATVGDVGAFEAAESPMSSSSSEDLTAVMPQETSPADRQQHTERPVQISGQRRLTEDDLMKHLSRRNTNRSGHSLSRETTQADSEEPAEINRLMSQMFGRTRQQNSEEEQTRHVGVMFKHLTIKGMGLGAALQPTFSDPFVGPLRKVRELLTKGRTAVSKPPVKTIIDDFSGCIRPGEMLLVLGRPASGCSSFLKVLGNQRSGFESIDGDVTYGGTDAETMLKQYRGEVLYNPEDDLHYATLSDVGVCSEVNEGESPAQYVKSFLQAVIKLFWIEHTLGTKVGNEFVRGVSGGEKKRVSIAEAMITKASTQCWDNSTRGLDASTALEYVSSLHSLTNMAHTSTAVALYQAGETLYKQFDKVLLIEGGRCAYFGSADDAVAYFKDLGFVQKARWTSADFLTSVTNQHERQIKEGWEDRAPRTAEAFGDIFSKSEQYQRNLAEIEAFEQETQSRMEEQQSDQAQELHNKLPQQARACTHRQFLVMIGDKQSLGGKWGGILFQALIVGSLFYNLPATSLGVFLRGGVLFFILLFNALLALAELTAAFESRSILLKHKSFQFYRPAAYAIAQTVVDVPLVLVQVFVFDIVVYFMANLSRTPSQFFISLLLLFLLTMTMYAFFRAVGALSRNLDIATRFSGVAIQALIVYTGYLIPPSKMHPWFSWLRWINPVQYGFECLMANEFYNLEIQCIPPNLVPQGPGATPEFQSCTIQGSQPGSVIVQGPDYIQVAYQYSRSHLWRNVGFICAFFLFFVTLTAVGMEIQKPNKGGGAVTVFRRGQAPHSVKAALESGRQGGDDLEKNSSRESIDTPDEKSAEEPSSKVNGEASGSDTAGEKEAVAKNETDFTWQNVNYTIPYENSEKKLLQDVQGYMQPGKLTALMGASGAGKTKHLSTKDQLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6A2</accession>
    <name>A0A9Q8L6A2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756001.1">
        <property type="nucleotide sequence ID" value="XM_047900378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6A2"/>
    <dbReference type="GeneID" id="71981108"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01230"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="27712" checksum="67997E9008D17ED0" modified="2023-09-13" version="1">MSTGINIGDIKRCTQSRPPITRNLSDLSQRLGRAVRALMEQGQGITFLPYYYFNDEKDEPLPPGVAPGVAPGVASGVAPLAATAGPSSSDSGRRNPSRTRMLPSRLRHSQTPSEEAGVAEDEDGDDFTDAGSVVDEVADKAFGTRKKKPKQLGANGLEVWNKNELQAREKIPPIWLDLVNSGCPRKVMNEYLQEHKRMYHQDPPPEGQCCNQEFPDIDVYPEKEVDSTSGIILPPPHMRRINAPTASPNVGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6D9</accession>
    <name>A0A9Q8L6D9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucosyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755940.1">
        <property type="nucleotide sequence ID" value="XM_047899541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6D9"/>
    <dbReference type="GeneID" id="71980271"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00393"/>
    <dbReference type="OrthoDB" id="202415at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF107">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040107291" evidence="1">
        <location>
            <begin position="31"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="163"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="49762" checksum="76501A7094276E92" modified="2023-09-13" version="1">MVMPILQSPLLWQALSAVLLLCILVQQFSLQPFPIRAKQISSALEHGDEQTIGKDTGAWSYDWARDHDNLNLNVEQCDAAFPELYDEVDRAVQYWGESGRKITSESIELVGGNDGGVRGLIAGQQLRIIQTRGLGRKDFRHRIIAVLQQIQTALNAAQSAGQPLPDVEFTVVVDDKPVVGEKPRALWGFTRAFANPRHDNVWVIPDFHFFGAPPEAEGWSLQQSKSREHDGPLDQKIAKVAWRGVAWTNPEVREPLLNVTEGKPWADVVQMSWDKKDSVIPMASFCKYRYVVNTEGRSWSARMTHLLNCDSLLMVHDVEWIAHYYHLLDTDTNCVRVERDFSDLEEKIKYYNEHLDEAQKIADTAKATFRERYTTPAATACYWRRLLRSWATVAFKPKTTEMTKVKNRLSSTEKLRGIAFEQFIVHDNTKDYPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6W0</accession>
    <name>A0A9Q8L6W0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756195.1">
        <property type="nucleotide sequence ID" value="XM_047899557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6W0"/>
    <dbReference type="GeneID" id="71980287"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00409"/>
    <dbReference type="OrthoDB" id="3650669at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="22527" checksum="71DE188F86BD8C27" modified="2023-09-13" version="1">MLDIVADGVPRETSCVFCRRCATTSGPSQVVQVRVVDDHPPSILCRHYSMSPNRGLVSPWHKARSYSTAKPTPPTPRPYRQAAPEQRLSRHPAYPEPPAEIEQKKSLFPRLWPFKPSQQGPIDLGAKDPARGVESARRVVKEGVLDPRYKSIARRVTALICALPLSIYLGYELFQRRFKGKERKRVVPPPAKPVEGSMNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7H9</accession>
    <name>A0A9Q8L7H9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01283</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756525.1">
        <property type="nucleotide sequence ID" value="XM_047900431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7H9"/>
    <dbReference type="GeneID" id="71981161"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01283"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF78">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="108"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="525"/>
            <end position="526"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="595" mass="65655" checksum="98E1334F58932EFA" modified="2023-09-13" version="1">MPLYNSLPDSILTDGVDVIIAGGGTAGCVVASRLAEADPNLSILVIEQGINNFNLPQCIYPALFPKNLLVDNETATALFWKGNKSALLGDREPIVPSGGVLGGGSSINWMVYTRAQRSDFDSWNTPGWSANEGWQYPPERDREHHGDSGPVNVSSGTFRARHAEDEFIDAAAKLGYRELKDLQNLDANNGTERWLRYVGPDGKRQDAAHRFLHPKLQSGGYLNLHVLVETQVVRVIFDENKRAVGIEYQPNPRYRSDGKPQVVKASRMVVLSAGANGTPLILERSGVGDPEILKRAGVPLVEPVTNVGKEYQDHHLSLWAYRTDLGHRDTINGFSDGRFDVADAIRKNDELLGWNSMDASGKFRPTEREVANLGPAFQKAWERDFKHAPDRPLMIIAMYLSYFGDHTTLPDSAEYVSMACWTAYPYSRGHIHITGRSLDDPIDFDTGYLNDEKEGYVDVKKHIWSTKIYRGELASSHPKFPAGSKAAVVERALGPVPDDAPFIQYSKEDDAAIEQKVRETVSTTWHSLGTCKMSPREKGGVVDRTLSVYGVKGLKLADLSIPPENVGANTNNTALMIGEKAADLFIKELGIKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7T7</accession>
    <name>A0A9Q8L7T7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transporter MCH2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756751.1">
        <property type="nucleotide sequence ID" value="XM_047899449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7T7"/>
    <dbReference type="GeneID" id="71980179"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00301"/>
    <dbReference type="OMA" id="AWCNGSI"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF315">
        <property type="entry name" value="TRANSPORTER MCH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="495" mass="52852" checksum="6673B49C86517ADF" modified="2023-09-13" version="1">MPTPRDWQDDKDPDVDKDLDITGTPAQDSTRPTASDNVEKSTTTPHPHPPSAPAPPPNGGYGWVCTACCAIINAHTWGLNSSYGVFLAHYLRTNTFPGASYLEFAFVGGLSISMAMLVSPAATLTTRYYGTKTTLFIGVFLEAGSLIGASFAYEIWQLFLSQGVCFGLGMGFLFVGSVSIPPQWFTTRRSLANGISAAGSGIGGLIYSLAAGAMLGSVGLAWTFRILGIIAFVVNSICAMLLRDRNKIIGSSQNAFDAKLFRRVEYLLLCAYGWFSMLGYVVLIFSLASYANSIGLGSSQAALVSALLNLGQGLGRPPIGYFSDSIGRLNMAGMMTALCAVFVFAIWIPAKNLGVLILFALVGGAVAGTFWATIAPVAAEITGLKHVPSALNLIWLVIVLPVTFSEPIALEIVGGTGSYIGAQLFVGFMYIAAAACLFLIRGWKIGELDEVARLKGQSVDEIDAVGVENDEDMAELARVAGRKRILTDFWKWRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8X6</accession>
    <name>A0A9Q8L8X6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757338.1">
        <property type="nucleotide sequence ID" value="XM_047901038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8X6"/>
    <dbReference type="GeneID" id="71981768"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01890"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="430" mass="47638" checksum="6CBA93BD09EACC7F" modified="2023-09-13" version="1">MPLPSHQHGASVPASGECTIACPTDMEAALGANAVRCAEMAACASPRKGKTPYEQEFAKRVEQATYQVKKLTTTAHNAMSKQLYSQSGLQDLVGAFGELLEKVAAQDKRKLKPKGAGYETRTINTFPTPAIIVVNTWAMLSSLIDDVYTLDHHRTSPQLAVDLEGAKFQRNGDISIVQISSHELDSVYLVDIYTLGNAVFDVKGAKHSTCSLRTILESTTISKLMFDCRTDNDVLLHTAGVRLAGVIDLQLLFLATRTKSGERKKLPSLPKVIGYAGGLLNTDKHKWNFDKHWGRIAMTTGPDEALELIEKFDGEWNNSECGKLSGQEDYKWVNQRPISKLIQKYCAADVVMLPAAYEYCINHRFWNEEWADRVEREMKWRLGMADAEVFEHNYTVLQAAPPGWDKVKQVDKTETAGKVAVKASTATLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9C4</accession>
    <name>A0A9Q8L9C4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oil body-associated protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757532.1">
        <property type="nucleotide sequence ID" value="XM_047902083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9C4"/>
    <dbReference type="GeneID" id="71982813"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02935"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="274" mass="31036" checksum="FDDD4444A0A390EA" modified="2023-09-13" version="1">MTSKRRVFQCSCCSPSLVHLLVILGSFYIYYKDQLADTAPSIHTTTSTNTKMDAIPVSNEAKGEPESLTNKTLETGAAMVQSFDPPKRLCAHFNAFHVYVNEPSRVSEANHYCAHVNDEVRQCLLYDSPLPTAKLIGVEYMVSERIFNELDPGEQKLWHSHVFEVKSGMLIMPTPPGVPQSAWEIAENKEMEQVVHLYGKVYNLWQTDRGDKVPLGQPQLMTSFTAKDHFDFDKYVGDRDRRFGVDSKHKAEVRAYIEEPKTHPNADALWNGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9S1</accession>
    <name>A0A9Q8L9S1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757901.1">
        <property type="nucleotide sequence ID" value="XM_047901566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9S1"/>
    <dbReference type="GeneID" id="71982296"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02418"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="23432" checksum="1399FEEB216515E9" modified="2023-09-13" version="1">MLGSIPPSFVEEALTRCQKHAAELLCLLQEGQEQGGLLKAGLYGYCALTIGLMYRLYESHDDPAIASMAHMRVEQAVEFLGNHQQHQPVFNNMILSVQSFRPNVDVAKALINPVSLASKATIRDASTLWHLLDYARMPEISPSSPDDTGVMTGLLQEVIEQGESAGLEEGSGYFAAVDAASEGVYAQGAFVEGMAGGSLWPEQLPQQDTELEVAPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA79</accession>
    <name>A0A9Q8LA79_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Urea carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02644</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758012.1">
        <property type="nucleotide sequence ID" value="XM_047901792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA79"/>
    <dbReference type="GeneID" id="71982522"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02644"/>
    <dbReference type="OMA" id="TLQMWNR"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF128">
        <property type="entry name" value="UREA AMIDOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160467">
        <property type="entry name" value="PH0987 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="3"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="119"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="1150"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1096"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1235" mass="135662" checksum="4E1E36A793FEA85B" modified="2023-09-13" version="1">MEAIRRLLIANRGEIAVRICKTAKQLGIHTVAIYTSPDAASLHVANADEAVLLSDDKSYTDGDQIISIAKAHSCDAIIPGYGFLSENAAFAKSVTDAGMVWVGPGPVAIRAFGIKHIARDLAKESGVPIVPGTAGLVETADDALRESEAIGFPVMLKITAGGGGSGLITCKNASEVRDGFATAKSRGEALFKDSGVFIEKYYPESHHIEVQVFGNGQGQVISFGERECSIQRRHQKVIEECPSPFVTQHPELREKLCKAAVALAETIQYASAGTVEFLVDDKTADFFFLEMNTRLQVEHPITELCYHVDLVELMLKQADAQLAGKGGLTAEYLTSLQRSGPFGAAIEARVYAENVLRDYAPSPGLLTEVHWEELQNSRIDSWVRTGLRISPNYDPLIAKVINHAKTRDAAIKGMNLLLSRSKVSGPPNNLDFLAAIMQDENYQSGRTITSFLKTFDYTPNVIDVVSAGAYTLVQDLVGRPSVGKGIPRSGAMDPVALSIANLLVGNDRAREGLEITLSGPELIFKGSAVVALTGAPIEATLDNDPFPMWHRKHIKPGQKLTIGRTTGGGCRSYLAVYGGFPPVSDYFASKSTSPIVAIGGYQGRQLAPGDQLGLSTSSPKHLEGHPSIPDSLRPAYSNHWELIALPGPHEEGYLTPEDIEMLYSTDWKVSHNASRSAIRLVGPEPKWARSDGGEGGSHPSNLVEYGYSVGSLNWTGDEGCIFAMDAPNFGGFASSATIVRADYWKMGQLKSGDTLRYKRVTLNEALQLRQHQANYIDGIEDAISKGHFEDVPKFEPGFQLSGQYQAAVLWERPATSTSPQVRYRQAGDDYILVDYGNEQFDLNYRCRVTALEKALHSPDAPAWWKDNLVTTVGCCTSITLCYDGAKVPRDHLIKHLQTLEEQIGDLSMAKVPCRRFRLPLTFESQEQFEATKRYMETQRPQAPYLPDNLDFVAKNNAFTAEQLKHNMLNGDLMAVVVGFFCGNTVSLPVDPRHRMACPKANPSRVFTPEGTFGWGGSCASIYPVDSPGGYQMLGRTIPCFDYYGFKAGFSPERPWLFQDFDILTFYEVSDEEFKRLLGLFRSGQYQFEWHADEFDMAEHNKLLAETEAEVRDIRAKQRQVQQKMIEAEKESLEKWRADKLKNKPDESTVESLLQDPEIVAVEAPVDANVWKVEVKEGDEVKAKQLVSILEAMKLEISVNASESLVSSARVEKVLVEPGDTIKAGGKIALLRVSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAX0</accession>
    <name>A0A9Q8LAX0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758265.1">
        <property type="nucleotide sequence ID" value="XM_047902461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAX0"/>
    <dbReference type="GeneID" id="71983191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03313"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000175">
        <property type="entry name" value="UV excision repair protein Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.540:FF:000001">
        <property type="entry name" value="UV excision repair protein RAD23 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="138"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="41881" checksum="C6969F5ABEEBFC21" modified="2023-09-13" version="1">MKLTFKDLKQQKFTIEADPSEKIGQVKEKISAEKGWEPSTQKLIYSGKILQDDNTIESYKIEEKGFIVCMTSKPKVAPSKPAEPSTPAKPVSTPAAPAAPQAAPSTNTSQPPATPSPAPASAAATSEPANFNDPSALALGEQRTAAIAGMEAMGFPRDQIDRAMRAAFFNPDRAVEYLLNGIPASAQQEERPAAASPRPASNQGQQPAAPAAPATETAAPSGDEPVNLFEQAAQAGRGGAGARGGAGAGAGAGAGAGGLAAALGGGQGGGQGGGQGGAANLEFLRSNPQFQQLRQVVQQQPQMLEPILQQVAAGNPQLAQIITQNPEQFMQLLAEDGDDDVALPPGAQQISVTEEEREAIERLCRLGFERDMVIQAYFACDKNEELAANFLFDQPDEPDESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB94</accession>
    <name>A0A9Q8LB94_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_03283</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757949.1">
        <property type="nucleotide sequence ID" value="XM_047902431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB94"/>
    <dbReference type="GeneID" id="71983161"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03283"/>
    <dbReference type="OMA" id="INWVEVP"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000015">
        <property type="entry name" value="General transcription factor IIH subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="14">
        <location>
            <begin position="80"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR015919-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO13583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="449" mass="49510" checksum="5A64E870B9D36C80" modified="2023-09-13" version="1">MADSDPEYDEENGPSTGTQMASRPKGREKARWEASANSKLAYQEAAGGSIEDVLGGREEAAKRKRLTKDTTPLQRGIIRHVILLLDFSEAMMEKDLRPTRYLLMLTYAKFFVREFIEQNPISQLGIVGMKDGLAIRVSDMSGNPEDHIAILGEYAKKEPKGNPSLQNGLDMARAALYHTPSHGTREVVVIMGALLTSDPGDIYDTIKACIKDHIRVSIIGLAAQMHICAEICRKTNQGDETCYNVATDDVDFREQLMKSTTPPVMRSTDAEALRRNQANLLMMGFPSRIVEEKATLCACHGQLTRGGYLCSRCGAKVCSLPATCPTCDLTLILSTHLARSYHHLFPLQNWAEVSWKRARQKGSVQCYGCLSGFPQVPAAHDTTQVEVQEQPRRKRAEGASESSRYECETCQNHFCIDCDVAAHEVIHNCPGCMSTAHLPGVEATNGTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBG0</accession>
    <name>A0A9Q8LBG0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transmembrane GTPase fzo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_03089</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758709.1">
        <property type="nucleotide sequence ID" value="XM_047902237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBG0"/>
    <dbReference type="GeneID" id="71982967"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03089"/>
    <dbReference type="OMA" id="RCERMIL"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008053">
        <property type="term" value="P:mitochondrial fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000638">
        <property type="entry name" value="Transmembrane GTPase Fzo1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="13">
        <location>
            <begin position="276"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="145"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="496"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="524"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO14343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="940" mass="103298" checksum="5CF7232D90CC0311" modified="2023-09-13" version="1">MSSNNPFQNGHAGPSSSSSGSGSSATRSTGRPQYMTVGSGSTSESAARLQAILDEDSGYGGSITGDDTTENVWHPGPTSDRFTPEHTPVRPGETNPASEHERKALASHVHQLYYNQNRTALGRAINQTVETLKKLQEMNAKWPAHYPTVQRPPSPPPAKATVRPGLSHTRTTRDLDDVVPTPRPGLPRRAGMSVGEHQFGEAEEDAAQQEPKVPEPRLVTPQLAQDFSVLKIELKMEGLAQSDIVHSLEKQSVAALLDNQINKGIRHLFALRERIEDTSSKVLVTGDLNAGKSTFCNALLRRKILPEDQQPCTSIFCEVLDCRENGSVEEVHAIPHGIVYNRNDESTYSVFALKQLEDIVIDSDRWSMCKIYIKDVRAVDQSLLNNGVVDIALIDAPGLNNDSLKTTAVFARQEEIDVVVFVVSAANHFTLSAKEFIFNAAREKAYMFMVVNGYDQIRDKNRCQEMILKQVAHLSPATFKESSELVHFVSSNAIPVAPAPDGPPGGSGGEGGSGSYSENGFDQPGKDNGDDEPSGRHGEPGADPRKKGKGKEKEAQDDFNELEASLRRFVLEKRARSKLAPAKTYLMNVLGDLGTLAGVNKDVAQNELDRVTEELRQLEPVFEKSKKARTEADESIATSIEETANDVYALTRSTLTDSISRIAESDLGVEYPGLLGASSYADDIKAAMLNQITETVRWCEERGREKTVQGVSGIKSLGFLHLGDQYTDLTFRSEKMFKSRRDALARQVDFDAEIWDFFDLANIWERQEKLAGSSMAVTLAGVVGTRMIGGAGWLDGALTATRVVGTNNLRRLFLPGLILAVTLGVSYVVSQIPQSLPRRLATKLSAQLGQIDYTHSNAQRVSSEVRRALKYPADKLREGLQRNMEHLQEQKKETDKVRVESEVARKYFGNLVRESNDIRSRVQRVDLEGPAPGIAASYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBZ3</accession>
    <name>A0A9Q8LBZ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758324.1">
        <property type="nucleotide sequence ID" value="XM_047901534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBZ3"/>
    <dbReference type="GeneID" id="71982264"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02386"/>
    <dbReference type="OMA" id="KCIGLEY"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="61896" checksum="C12A72D9EF24E45D" modified="2023-09-13" version="1">MASIMEAGNATSTSLPGAIHATIESVQTGFLSKAFENGSPVSWFSVFLTLFAAAVVYDQLSYRSSKGPLVGDFWKIPFVGPFLESVNPRFEAYHRKWLSGPLSCVSVFHKFVVIAATRDMARKVFNSPMYVKPCVVDVAHKLLRPDNWVFLDGKEHVEYRKGLNGLFTRNALETYLPGQQEVYAEYFEDWLRESEAAGSSPKPWVYNIRELITAVSCRTFVGHYMSREQVKKIAEDYYYITAALELVNFPIIVPFTKTWYGKKAADQVLDVFSNCAAKSRVRMRQKGVEPECIMDRWIVQMIESDKYRERIAKGEKVPDEEKPAMLLRNFSDIEISMTVFTFLFASQDATSSAASWLLQIVADNPEIMRKVREEGDKFRPDHNQDVALDVLEKMQYTRSVVKETLRYRPPVLMVPYLVKKDFPIPESNYVAKKGTMIVPSTWLSLHDPEAYENPDNFVPERWTTGNAEEQGKNWLVFGTGPHYCLGQTYAILNLMLLLHKMSASYDWKHKVTNKSEEIKVFATIFPMDDLQLSFSRRAGHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC03</accession>
    <name>A0A9Q8LC03_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758988.1">
        <property type="nucleotide sequence ID" value="XM_047901527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC03"/>
    <dbReference type="GeneID" id="71982257"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02379"/>
    <dbReference type="OrthoDB" id="3635925at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="44"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="40826" checksum="F034241DAFD9E5F6" modified="2023-09-13" version="1">MTAHVDMATPYVEGHRFTRLETWNHQPGLWIVTILSFAYAFITLLIRYSIRRKLTRADYVLWAGFALALVSYALMLNALRHGAGQAPEALSDGSFATSAKLVSASITFLLLACGCTTSSQLCQLEELVPGTTDKMLCWMGIAICIFCSISTPISVSAGCSSSKVLSAGSDQCSGATLRWTIAMALLIINFLVPALLPFRLFRLLHTKLQRKAGVYLAFGFPLLCVSIAALTVYLYTRFVRDGQSGTGAVDFLCCLQVLLGWALIAPTIPIGKALAIRFTTHGTMVLSHYGSSNDGTVAGGARIGAQNHGPHRPSHWNDYEFNPDRFMHTSSIRHEPHDQIAKLSGSLDYGIRKTVETEVESARVTDFIMRQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC62</accession>
    <name>A0A9Q8LC62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759078.1">
        <property type="nucleotide sequence ID" value="XM_047907812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC62"/>
    <dbReference type="GeneID" id="71988542"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08664"/>
    <dbReference type="OMA" id="SDMDIQP"/>
    <dbReference type="OrthoDB" id="4977at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="130"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="411" mass="45085" checksum="59FF14B44037F38C" modified="2023-09-13" version="1">MADEDSRKHLPGIDTAPDVYETGNDVDDDTTTSTFQTSQSGADSAGSGSDTTEEDDDDYGVSRRRLFPQRARSRFGQRSRNVRTDGVDLSDRVDGKRKGYRVRRRQYDDDDGEDESLEARIARLRREVEECKAQAEEERKAGQEEEDDDDEDGENDTTKEVDALSRLLAGIDLPPTNSAAKRGHRRKSSVFHDAPTTSSQSQPEAPPDDQPLTQITTFDSRLAALESALGVSSILDSTTETSTLSTPLLPSLTLLDQQLSSLTTATSLSALEAATSKIQSLKAQADNLSSLSAEGVEEEGASTTLTPSDLEKLQSLYTILPTLQSLSPTVPALIMRLRSLNHIHTAAAQASDDLEAVEQRQAEMDRELKMWREGLEKVEKAVVDGLESNGRNGGMVKKWVEELEGRVKTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC86</accession>
    <name>A0A9Q8LC86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759207.1">
        <property type="nucleotide sequence ID" value="XM_047907521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC86"/>
    <dbReference type="GeneID" id="71988251"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08373"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="110" mass="12664" checksum="FE5A223E0D5B69B9" modified="2023-09-13" version="1">MLTARDPTRIPLLKASIGLSTEKVETQQCTCNAQYKYEKSRAEYSLLLQHAGMVRQEDGRRGEELRKLQAENEELRRSLDAAREMELVSGKQIRELERKAVDAVKVWMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCC4</accession>
    <name>A0A9Q8LCC4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tetrahydrofolate synthase</fullName>
            <ecNumber evidence="3">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07946</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="3"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759208.1">
        <property type="nucleotide sequence ID" value="XM_047907094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCC4"/>
    <dbReference type="GeneID" id="71987824"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07946"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="539" mass="58960" checksum="510BBE260B87B3A4" modified="2023-09-13" version="1">MHAGLAWLGLAPKTARPAKIFQSCTRIADFKVPLGHPVRQASPMASSSQNVSVSIQSNGDDRTYEQAMAILESRRRTNRPLTSADSAPKNRGVPSKVGMAEWLSALGHTEADVNALSIIHVAGTKGKGSTCSFIESMLRAHASRTSFPRNIGLYTSPHLIYPEERIRIGFQPLSRDLLAKYFFEVYDLLPQLATELDISKSPIERGPRYLQLWALLAFHVFIREGVDATIVETHSGGEHDATNVVSKPVVTAVTSLGMDHIDMLGPTFEDIAWHKAGIYKKGAVALSTTQAPSALDVLQQRSKQVEASLIVVDQDSRLPAKASQLNPSVQRKNASLAAAVAQAFLERTAPAGQGELTVEDVRMGVEQWSWPGRYQTVTRGQHTWFLDAAHNEMSIALAAQWFEETSLDFAGPERGVSRTVVFSHINELRDADALLEQLAAALKACSVDVQHVVFTTYADAVESASKVSESSLYFETIWRRYLPNTLVTHEPTITGAVNRVKTFAAEDRVAHTLVTGSQSLVGPVLRLLQHDHAVRSATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCC7</accession>
    <name>A0A9Q8LCC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759282.1">
        <property type="nucleotide sequence ID" value="XM_047907478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCC7"/>
    <dbReference type="GeneID" id="71988208"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08330"/>
    <dbReference type="OMA" id="GQHEVCR"/>
    <dbReference type="OrthoDB" id="3632630at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="41169" checksum="82E91286E13E0B9C" modified="2023-09-13" version="1">MASPSSSGVNSVASTPSITITDDHGRGESLKLPDASLSAEPERPRSITFEAPTPALKDLKPVPDGTPPIGGIKGTEVKNSLETGPGAAPTPDPTSTAKKERPAPKRTGSGILTELKQQMSSNNLFHHHKTHGVKANGIKSVATSGTASPRTPEVQALFEKDLKGDRHCPNLDAVNRALESLRASAAAGDQYVSNLEELAKVIQRSRTDSRKALTDAMKARDQGQHEVCRALCLSIVQNKHAEADTQVYAYNILSTQASPGQAMTYLNEAYKLAKENEARGLNCDKMLEVIAVLREGAMAKDGAVASKGGKTGSKGPSSNGVAGSANSKLDLDAGELDKKLKNLAMEDPNLRRDSLSPKDLLAVPKGDLPSGMLTPKTEKIFKWAAKQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCF3</accession>
    <name>A0A9Q8LCF3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759015.1">
        <property type="nucleotide sequence ID" value="XM_047906993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCF3"/>
    <dbReference type="GeneID" id="71987723"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07845"/>
    <dbReference type="OMA" id="WTYFERG"/>
    <dbReference type="OrthoDB" id="286811at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="27956" checksum="DB8696C5F29BD179" modified="2023-09-13" version="1">MRVASRLLASVQKGAQFLEAGTPTGLTGVSTHASPRTTLLYTYHTTLEKLKQFPEHSVYRQSVEALTKHRMQIVEQVKPSGLEEWQKRVQAVADSRPDAFKTVPIVTPSGNKEVNIVWKAAAVQAAKKRTDEWDDEVVGKPHEEGIRTEEERAYMGKELARDLTEEHRQIPRIESEPPLSLEQINDIEAKIGAGLIEEVIMVAEGESVLCDTLLEAQVWEDLEEKPQDGQWSYAERDTFTQGTQAPPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCH1</accession>
    <name>A0A9Q8LCH1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_08290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759311.1">
        <property type="nucleotide sequence ID" value="XM_047907438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCH1"/>
    <dbReference type="GeneID" id="71988168"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08290"/>
    <dbReference type="OMA" id="HRWKEVK"/>
    <dbReference type="OrthoDB" id="47179at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03488">
        <property type="entry name" value="Topoisomer_IB_N_htopoI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.41:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.11.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.15.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018521">
        <property type="entry name" value="TopoIB_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048045">
        <property type="entry name" value="Topoisomer_I_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00176">
        <property type="entry name" value="TOPO_IB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="10">
        <location>
            <begin position="412"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="778"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="894" mass="102040" checksum="7A26E5C8EABA67E3" modified="2023-09-13" version="1">MSDSEDDRPLVAKSKETISKAVDAAMDKQNGETNGAALPGISIANGPVEDMDVDKPTSNGKRKASMTNGNSYKEASESDDEDDVPLKKRKTAATSDDSDDDVPLVKKTQKPIQVTAAQIGEDSGDEPIVKKLQKEKAMIEKKAEKEAKEIRADESKSKRKSKKPVSDDEDDEPIAKKTASTKKQTNGAKRIKKEESDEDDKPLAKKKAPAKKAAAKKEEATPKKGKGKVKKEESPEEDGEEEEEYRWWEDPSKGDGTTKWNTLEHNGVVFPPEYEPLPKNVKLLYDGVPVSMHPGAEEIAHAFGAMLNSTHNVENPTFQKNFMHDFKEKLEETGHAKDPQGKQVKITKFEKCDFKPIFNHVDAERQAKKALPAAEKKKLKAEKDEIEAPYLYCMWDGRKQKVGNFRVEPPGLFRGRGEHPKTGKWKKRVLPEQITINIGKEATVPKPPEGHQWKEIKHDNTATWLAMWQENINGAYKYVMLAANSDIKGQSDYKKFEKARELKKHIDRIRKDYTKELKSEIMAERQRATAVYLIDQFALRAGNEKSDDEADTVGCCSLKFENVTLKPPNKIIFDFLGKDSIRFYDEVEVSEQVFKNLKIFKRSPKKEGDEIFDRLTTSGLNKHLSNYMQGLTAKVFRTYNASYTMSTLLQQMTPDHSGKTAIAEQVKAYNDANRKVAILCNHKRTVAAGHAQQMEKMEDKINALRYQQYRVKLMMLDLDPKQKKKRGAEYFELPEGLDKEWQETHHKALVEEQRTKIQKKFDKENEKLEADGDKPMKAKELEERMEPVKELEAKLKKEFKTGKVEAEGKSASIEKYEKDLEKLDTRIATMQTQAEDRDNNKEVALGTSKINYIDPRLTVVFSKKFDVPIERFFSKTLREKFDWAIKSVDEDWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCK5</accession>
    <name>A0A9Q8LCK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ams2/SPT21 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758624.1">
        <property type="nucleotide sequence ID" value="XM_047902400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCK5"/>
    <dbReference type="GeneID" id="71983130"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03252"/>
    <dbReference type="OrthoDB" id="3199820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057725">
        <property type="entry name" value="Ams2-SPT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042403">
        <property type="entry name" value="Spt21/Ams2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147:SF1">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25823">
        <property type="entry name" value="Ams2-SPT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ams2/SPT21 N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="835"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1169" mass="127324" checksum="37C1AD0DD4410D82" modified="2023-09-13" version="1">MESGGFGHDGSLGDLPTRPMRVKILYTFDAENKTTCLARFPDTLNIPVVAIDEQSQVGVIDLQQCVQAMLSASPEIMSKLDTGDFTVYTFDYTELDTPIVGQGRLSALLAQPTSSEGKSMITGRVCKNVQAIFSGGVKEILEVKFRLTPLSRPSHNEMMRQSEGFRSVSPATSTGFDPNAWNASQQNKAQQQTIDYFNFDGLNSGSDNGAALLENMFGIAPGSSGESSGLQHSGGVGVSETPTDTAYGFNPAFSVQSHSAPGSRVGSPVIHPGSSSLNDSLRHQSFSGHPSNLAEQPRPDSRASVRSETSPSHHQRQASTQSYHEQQTERQTEFLYNEDGQPRKRAKVMQADWRGKSSFGTKTRDLRVTAATASSMHMHRPIAKRPSAPGTDLEPPPRVPTPVPQRRILPRPSMQPTTSRSMLRQASTVDSDFMSDVDQMSDAMSSPEGSSPANSVNADATPMDIPSSPPLIPGYNLPTPSSPGLPTLPSRMLDSGYMSGTIMESMENDDNRSPDAEDLEMAAKYRARSHQRDPIVKIEGATTSDAPFYSMEPAPSDPNGNLPSGQAHGNQGQQSRPLAPLKRSTTSDVRPLLPRGDSTIMQAEAAGSRRGSLALPPKPIARAASQEQNSKAPSKQKRQPLQRSRTTYNDSEAGSPAPSDTEGRPRGNARSGSAVPRRKLIQDRLNAKIRNGEVPIYCTHCGAIETTTWRKMYIKVCDRAPEKLDEIEGEGETIGIQELEKNQESGEITKFRIRKCIKNVKEQAPGPGFDEVNVCNPCGLWFKKFRDMRPEDRWHRKVVRKSKKSKNNDDNATDGMEPPSEAFFTDQVVPDDAVESGSADDAQADAGAEQEARPAPARRPRAHSMELGRGGGDGKPGAARQAAAMRREIQSSPVHFGSQRSPIELDLTPAKPTRRLLFPSPRQSGEVRNLDTCLDSRPASRSGEDDPVQKPDVKIVTTEETTLNVYKAFTYDKENMAPLLEENDDLSHLFDGSPSAVFKTPLPKTPSKSTPRSQKHFNDLLKTPTQSSRKRKPLTPSQNAANNADMNLNANDFMTSPTSNRYFLRSTPSRLERTPGSRSVSGGSQTQLAEPSPFSRHLAAMLSDANGMGDATFTSPSRQYDFSDLPTFNTPGREVDWKGLDEILSSEFANFDDGNGVSFDSEAATGEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCV6</accession>
    <name>A0A9Q8LCV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxylase/desaturase CTB9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759521.1">
        <property type="nucleotide sequence ID" value="XM_047907026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCV6"/>
    <dbReference type="GeneID" id="71987756"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07878"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="195" mass="22185" checksum="415AEEFBCD076146" modified="2023-09-13" version="1">MLKELTGASHVYVFSHVVRKDSHREALDMPKELRDDEPIPLATPAMFAHIDYSIYIGSRTVLCTVCDARTVPDSDLREITLKIPTQLPANYYTLRTGIPNSPYGPEKDDLTREKPNQKLWQVAANPGHKWYWPSGMKQDEVLLIKCFDSRTDVARRAPHCAIQTPMDQGPPGESIEVRCLVVWEDQVPNDERAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD56</accession>
    <name>A0A9Q8LD56_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759628.1">
        <property type="nucleotide sequence ID" value="XM_047907589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD56"/>
    <dbReference type="GeneID" id="71988319"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08441"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="193" mass="20195" checksum="EBEF2DA57D1939CE" modified="2023-09-13" version="1">MDKLKKLFGGDKHTDQPAATRSSSAAAAPSASAASRSSDAHHPNNVVLHTTLGDITCIMYSDLTPRTCKNFATLAQTGKYDGVIFHRIIKNCGDPTGTGRGGSSIYGAKFEDEFVSSLKHEGKGTLSMANAGPGTNGSQFFITLAATPHLNGKHTVFGRVTDGMDVVDKLGAVATDSGDRPKSEVKIINATVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDV3</accession>
    <name>A0A9Q8LDV3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_08787</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760003.1">
        <property type="nucleotide sequence ID" value="XM_047907935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDV3"/>
    <dbReference type="GeneID" id="71988665"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08787"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="99"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO15637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="456" mass="51634" checksum="C61D03370838464C" modified="2023-09-13" version="1">MWGVISSDLTATSSLSPFNIALCSSSLEQYRETLCAMSFTLLRRAWKSIHPLAWKPLVFPNQGIASIPANEKVEEETIPGYIATRYYPVRIGEIIQDRYQVVGKLGFGLSSTVWLARDLDGCRHVALKLYVQSDCLESELDTELDVYRRIESAPNHHPGRHAVRSMLDSFELATPSGRHRCLVHEPLWDSALNIKHRNPVRRLPQPVVAFLLKRLFLALDLLHRECHVAHTDIKEANILLPADPSVLTHFEQQELAEPSPQKEVDGGVIYLSREMGTPKAFGAPVLCDFGSAVALDDGQEHREDIQPDVYRSPEVILDVPWTYSVDIWNVGCMVWDAFEGEHLFTGCDPEHGAYRGRAHLAEMIALLGPPPPSLLARSHLRSKFFSKEGDFCAGIAVPRTRTLDHRESSLQGEENKEDRECFLRFVRKMLQWEPEARSCARELAEDEWILKHTTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE19</accession>
    <name>A0A9Q8LE19_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_04582</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760136.1">
        <property type="nucleotide sequence ID" value="XM_047903730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE19"/>
    <dbReference type="GeneID" id="71984460"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04582"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:protein K48-linked ubiquitination"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ZNRF_ubiq-protein_ligase"/>
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    <dbReference type="PANTHER" id="PTHR46661">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR46661:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="zf-RING_2"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="FYVE/PHD zinc finger"/>
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        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0458">Lysosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="20">
        <location>
            <begin position="152"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="505"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="140"/>
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    <feature type="region of interest" description="Disordered" evidence="18">
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            <begin position="197"/>
            <end position="224"/>
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    <feature type="region of interest" description="Disordered" evidence="18">
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            <begin position="241"/>
            <end position="345"/>
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            <begin position="358"/>
            <end position="405"/>
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    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="432"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
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            <begin position="307"/>
            <end position="317"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="18">
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            <begin position="371"/>
            <end position="389"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="18">
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            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
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    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="PROSITE" id="PS50089"/>
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            <dbReference type="PROSITE" id="PS50178"/>
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        <source>
            <dbReference type="EMBL" id="UJO15770.1"/>
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    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="60409" checksum="F47989E16B4E5B9B" modified="2023-09-13" version="1">MSGDPRRDAPPTYPGRPAHQHDVTWLDFLRTAGGTVPADPSPQQSSDRQNSAERKRRHTGSEPERRTYPYPGKPSVISASSSRSIGQQGNSRDTAIDLTSPPARSSRETAIDLDPTLSRPYRPSSSRMHSGGNGSLGGRRESDIVLPRWQSDHEVNTCPVCSTDFSFWYRKHHCRKCGRVVCASCSPHRITIPRQYIVQPPSPSTFYEDESSPASPPNSRGHLGGGEIVRVCNPCVPDPWTPGTTSAQAPVAPVPPPPPRTSSRQLSPTRDTRLYPGTDPRLRRESDQGERERPDRYRHVLPPGRSRAQSYQITPSVANRDPRLQAQGGIRVTSRGTGSREGAFPRLSSHYESRYSVGRAAHGTPPAPSHASRSMPTVTAPHSHSQPDASQLGAPGRPRREVREEDECPVCGIEMPAGEAIREAHINDCISSRFSSTPTQPRSVPTATSPQVPSPTALAGSHASSNAPTAEGSRPRATSYRPRGMALYKATEKDCQDAAGEVQECVICFEEFEPGDEMGRMECLCKFHRICIRQWWDTKGQGSCPTHQLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LES0</accession>
    <name>A0A9Q8LES0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alpha-galactosidase</fullName>
            <ecNumber evidence="2 5">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_05373</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2 5"/>
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        <property type="protein sequence ID" value="UJO16102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760468.1">
        <property type="nucleotide sequence ID" value="XM_047904521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LES0"/>
    <dbReference type="GeneID" id="71985251"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05373"/>
    <dbReference type="OMA" id="MSQQFHR"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000118">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031705">
        <property type="entry name" value="Glyco_hydro_36_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031704">
        <property type="entry name" value="Glyco_hydro_36_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16874">
        <property type="entry name" value="Glyco_hydro_36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16875">
        <property type="entry name" value="Glyco_hydro_36N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005536">
        <property type="entry name" value="Agal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00743">
        <property type="entry name" value="GLHYDRLASE36"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040222610" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 N-terminal" evidence="10">
        <location>
            <begin position="46"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 C-terminal" evidence="9">
        <location>
            <begin position="663"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="562"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="378"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="498"/>
            <end position="502"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="540"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="744" mass="81988" checksum="4FCDA87F11DD0999" modified="2023-09-13" version="1">MKTVLAGATLLAGLAAGQNAITADGTNFTLTANNASYLFHVDTASGELISDHWGGSVNDFIPPVSLFQGGWVDQRPPNTGLSNIRREFPDIGRGAEFRLPAIHIKHADGNTVSEFNYQSHQIVDGKPKLPGLPATYGGSGDVSTILVTLYDNYSDVTAVLSYSVFPKYNAIARSFQITNNGTSNISIERAASFSIDLPNQELDMIELQGDWSHEANRVKRRIDYGETSFRSSEGYSSHLHNPFFALQSPTTTESSGEAWGFNLVYTGSFAASAERYSTGDVRILLGLNPLHASLPVAPGETFTSPEAVSVYSAQGLGGMSRSLHDLYRNHLSRGKQTLQTRPILLNSWEGLGANINDTSMVQLSGEAEELGIELMVMDDGWFGVEYPRDNDTMGLGDWTPNPAKFPDGLRPFISDINNFTVLNSTKDLQFGIWVEPEMVNPNSTLYREHPDWVMYTGNHPRTLTRSQLVLNLGLKEVQDYIIDFMHKLLDSANIQYIKWDNNRGISEMPYPAADHDYILGLYRVIDDLTTSYPDILWEGCASGGGRFDAGLLHYWPQSWTSDNTDAANRLTIQLGTSLAYPPSAMGCHVSAVPNGVTKRNISITYRAHVAEMCGSFGFELNPSELSEDESSHIPAIMAEAHDVNPIVISGDFYRLRLPDDSNWPAVQFISEDGNRALVFAFQQLATVKPAAPPLRLQGLDPTARYFNDADNATYSGATYMNAGMNVNFPTMDYQSKLIRLYQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY5</accession>
    <name>A0A9Q8LEY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759809.1">
        <property type="nucleotide sequence ID" value="XM_047907115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEY5"/>
    <dbReference type="GeneID" id="71987845"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07967"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="38234" checksum="A179051F1E781802" modified="2023-09-13" version="1">MADMTAAQLFTVEGIERERQLNDQRDAEEAERQRLLSSQVIDQYFRIIHCQPSTAEKNTTTGPGPSNAEDDTATGPDTRVPQIPPFDPDVQSEIDVFFRRSPQTRTSAHARWLLDLLWRIMSADYGLPLTEKLTDCEHIHWLGVALSYGGLVPGDEGLKDIYDITDLDYAIRKPAHELGLNLKAVESSILLYFRYTKGLTVLYPGCIDTFWAPKGLEVLAFKMCYDTHFNIRLASDKSQMLNITAGIVLTTRRYYDDRHPWMQALTISNQKLHEEIKAAIDMREGKDKEMREEVVGERKKLQKKQKKMEKKERRSCMSWLSGTRSRSFWPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF32</accession>
    <name>A0A9Q8LF32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760599.1">
        <property type="nucleotide sequence ID" value="XM_047904004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF32"/>
    <dbReference type="GeneID" id="71984734"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04856"/>
    <dbReference type="OrthoDB" id="2788868at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="2">
        <location>
            <begin position="308"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="56145" checksum="4491B4762D138E3A" modified="2023-09-13" version="1">MALRTTPEKVTQERDIDHVKGLLCETALELAVLGEVDSARDLLSLLASATGEPVSLFQAGLSFASRATGQWPVGTSEEAKSQDALSKLRQRCKRDSSHGFPIGGNVYDESGLKACLEAKDVCGADSTTGSSAMGKGVRLVQALDISLKLHYSGGPLDPGSQVRRSARIASLSDSAADQSPETVSTTSARPGGVAVADLDAQSAEVVGMIAVRWRAYQQIRYLAEAESLWPYWLAGLLADALSLDRDDLTAKGQALVETFKSRLDHGFVPSILAGKSMKELLDLAAKSSFDRMTEDGHPESSRMFFKAGASEEEIEALEGRLQTVLPDDYREFLQITNGFGVGESGIYNGYFPSPALHATVDVKWDEEEYLQLPVELLQLPRELEQLATSHWKQRSTRPNGYLDWEGALPIFDRVLELGTLDIYNIWLVHPMLVEQCRNAYHEMYRNANKKQRKRILLAMESFAGSKGAFEQLHWCCVTWAAGGSACMTAYASFRDYIEAMTLRSMQRRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF38</accession>
    <name>A0A9Q8LF38_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_04444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760648.1">
        <property type="nucleotide sequence ID" value="XM_047903592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF38"/>
    <dbReference type="GeneID" id="71984322"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04444"/>
    <dbReference type="OrthoDB" id="3630828at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="12639" checksum="B355A441EBAA57B2" modified="2023-09-13" version="1">MAFLNEDSHTPDLPEIGSLQLSESPTDSLDAADDSWVYPVPLSHSNELWSCTYSHEAVIAAFKDYYAFLTRMYLDEDDVITPPVSGWPDITADVLKDLGKADEVVASPRSIPYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFC4</accession>
    <name>A0A9Q8LFC4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760811.1">
        <property type="nucleotide sequence ID" value="XM_047903792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFC4"/>
    <dbReference type="GeneID" id="71984522"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04644"/>
    <dbReference type="OMA" id="NCQGANQ"/>
    <dbReference type="OrthoDB" id="3641806at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040194714" evidence="1">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="11990" checksum="85B56D5002C9AD1D" modified="2023-09-13" version="1">MLFPTTLLFAALTTLVSSAPLLETRQAATVVRFYTEKDFGENLPTSVKDSVSSFKIGVYKCRFFEHDGCTGKSQWFDEDWHNMRARGGNYGYKGDQNDEVSSAICST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFE4</accession>
    <name>A0A9Q8LFE4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760787.1">
        <property type="nucleotide sequence ID" value="XM_047903488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFE4"/>
    <dbReference type="GeneID" id="71984218"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04340"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="16413" checksum="16FDB6A37C423ECD" modified="2023-09-13" version="1">MSKARARRLKRKIKEGRPTLAPDEYKRRRQQQEEGERRNRQILQQKRLFPAPADLEREKFEEYAPGLCCDLREHKTIRTTQNDTPYRARAIWFNDFDERHTFHKKHRQARQLYNILVHRLIKGGTLHSSSCSSSRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG16</accession>
    <name>A0A9Q8LG16_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dimethyl-sulfide monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761322.1">
        <property type="nucleotide sequence ID" value="XM_047903253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG16"/>
    <dbReference type="GeneID" id="71983983"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04105"/>
    <dbReference type="OrthoDB" id="5561043at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF16">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="406" mass="44378" checksum="FE31EDC5E7922EE4" modified="2023-09-13" version="1">MAAATKSIGFGVTISTTYEAPYHLARRLSTVDHLTNGRLGWNVVTGYLDSAARNLSNGAENLGHDERYEMCEEYMEVVYKLMNASGRSDAVKLDRGSGVYTDPELVREINHKGKHFTVPGTHFCAPSPQRTPVIYQAGTSKAGKEFAARHAEAVFVSQHSPAAVAKNVAEIRSKAATLGRDPNSIKVLAKFCPVLGRTQEEADAKYRDYIQYGDYEGALALFGGWTGVDMGPYGDDEELRYVESNAIRSYIEGLISTAPDVNGGKWTKQTLAEHIVVGGLGATCVGTAEKVADEMERWVEEGGVDGFNIAYALMPQTFEDVIEMLVPELRRRGLFWEDYCAPGGTYRENLYEQPGQREPPEAHPAAKLIWHPPAEGSHDEHGGANGDGCQSGASSEIADWVLENLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGT0</accession>
    <name>A0A9Q8LGT0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Complex III subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_06453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761727.1">
        <property type="nucleotide sequence ID" value="XM_047905601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGT0"/>
    <dbReference type="GeneID" id="71986331"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06453"/>
    <dbReference type="OMA" id="NEDCVEE"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000003">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="12">
        <location>
            <begin position="82"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO17361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="149" mass="16707" checksum="EFF6273EBCFB238E" modified="2023-09-13" version="1">MGIWDYVTDLYEALSVQETYAEEPQKDDGGDEGSDEGGEEKEESSEGGEGESDDAGEDGGDEGGDDEEEEEEEEEEEDEPEDPKPIIEENCLKTKECAPLKHHYDACAERVKHQEETHGKANEDCVEEYFHMMHCAAQCAAPKLFRQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN7</accession>
    <name>A0A9Q8LHN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762192.1">
        <property type="nucleotide sequence ID" value="XM_047904741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN7"/>
    <dbReference type="GeneID" id="71985471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05593"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="54470" checksum="D042BC7648877365" modified="2023-09-13" version="1">MGDEQPRLRDLMRGCTDSQPRLGSTPVARPEGNTVQQNPMESFVPPLTRHNTWENFDSAHDEPFNGQRASDLRMTIQQSAEPWSIQRPHFVPPRMPPSKRLSSQQFKLCVHLATAIILRVKVGDNATVDALRPQLVRFQGELHDEDHEAFQDRAEKRCRVDRALQGSDQKLKKVSLRKIGAAIAIIPLCPENRGDAAYTFTRDLEKIFDGVYERDLEAYFEDNFIDRMYDYIRSRGFLQHFHDRVEVFRRSDSMSPNSGNDEGSNANKTPKTPRTTHDTTPNINSMTGTAGPPRSCFIPGTYYWPDKLPGYKPPPLIESSLNRPPLPPWTKTEENQKQHGCPRFCTCSTCHVRKENGCAYLYSANRSEGGRLPEFNTDTNCGIDCPNICIYSCYCDTCKTKGINGYRPSPKQIREAEREAEEARLSTRAGRREQRLKERAERKAYEAYEASMRTRRQPTEAEREAEREADAMMREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI15</accession>
    <name>A0A9Q8LI15_PASFU</name>
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        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_05417</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO17755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762121.1">
        <property type="nucleotide sequence ID" value="XM_047904565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI15"/>
    <dbReference type="GeneID" id="71985295"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05417"/>
    <dbReference type="OrthoDB" id="10615203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
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    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040277089" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="18"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="89"/>
            <end position="128"/>
        </location>
    </feature>
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        <location>
            <begin position="159"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="215"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="245"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
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            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
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            <begin position="37"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO17755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="31040" checksum="642E46CE58EC185C" modified="2023-09-13" version="1">MRLTTLLFGSLAGFAIAAKLPDCAGSCISQAVKTTGCSSRDSQCICSHDSFESSVKQCTVTNCGEGKASGAAAFVADFCKSVNDLKKRHGRWQGNQKQSKHSKNNSQYHQQRDTQYKQKDFKGKVVTPPKYGKPSAPVYAYVASMTVWDSAPSATIYAPGQSPAAKPSSNPYNSGSGQGGWAKANGDRPAYAPPAAPAAPSPTIYAPGHYPAAVPSSNPWNVGSGHGGWPKANPGEQPAHPPAAPSAAPSYRPSYAPSYRPSYAPSMASAAPSAAPSGYWAKSTYGKAKGTYGRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI87</accession>
    <name>A0A9Q8LI87_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LI87"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_05237"/>
    <dbReference type="OrthoDB" id="4821037at2759"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
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        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16033" checksum="C0F221FD307D1AA9" modified="2023-09-13" version="1">MAYFSRTQALYTDGAYDNMSSKKGGCGYAFFSASLGRWLLAGWSLGKMQSIVDCELLALLAAMQHAADNCVDTKTFILRTESTDARGRITAAREGRPLYHGARTATIVNRILGEIELLEFRGVEVRLEYVKAHSGVEGNELADMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI89</accession>
    <name>A0A9Q8LI89_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762257.1">
        <property type="nucleotide sequence ID" value="XM_047904719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI89"/>
    <dbReference type="GeneID" id="71985449"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05571"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="15891" checksum="B5AB21A026065AF5" modified="2023-09-13" version="1">MDRTDSLSPRFSDNGSPRFTEHFNASPPYQPFQPFQGDNDPPTPQYVTAQESPIQHRPSDKRPPPLSPSEIVAPYPEFYESNDEGKEVVVPSVMPEAYERPPDARPQRRQICGLPLLWVLIIAGVVVALAIGLGLGVGLSNGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI92</accession>
    <name>A0A9Q8LI92_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762241.1">
        <property type="nucleotide sequence ID" value="XM_047905747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI92"/>
    <dbReference type="GeneID" id="71986477"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06599"/>
    <dbReference type="OrthoDB" id="5372859at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38009" checksum="1E9890F02937033D" modified="2023-09-13" version="1">MCNDCSMTTSTTTSSSPPASIKTNMAAIQTAPVVNIESLDINALHALPAEVLLDIIPHIPFSAHGLRCLCLTCARLNTLIRSHENSLVNDIKHIQIPQSSLQLFPSLKTDTFEGLSKLHQRLSTLDDLHQQWLQITSNGPELDWLKGRWETIHKTGLLLLYRLQDSGSYCNKVAMLNGLPATSLACLLFKLISSIKILRIYGPNPINGNYASGDIMARSDIELAFEEMLLLHGPTFFLAMLRAKSDRAKTCQTPSQWAIDALESEVAGMVERQMPSPEGIPKPPTLTSCMRRAFAAKLGCHVGQNVGKMWEVLSGTAFDEVDEGKMGLIVRGEEIEKGLRRVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIC4</accession>
    <name>A0A9Q8LIC4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General transcription and DNA repair factor IIH subunit tcf-29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFB1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762045.1">
        <property type="nucleotide sequence ID" value="XM_047905668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIC4"/>
    <dbReference type="GeneID" id="71986398"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06520"/>
    <dbReference type="OrthoDB" id="360521at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13229">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027079">
        <property type="entry name" value="Tfb1/GTF2H1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013876">
        <property type="entry name" value="TFIIH_BTF_p62_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12856">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08567">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BSD" evidence="8">
        <location>
            <begin position="254"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="485"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="682" mass="75929" checksum="61219627885C6F9C" modified="2023-09-13" version="1">MFYDATSYYARDFPGNTEMPATTATVAYKKKKNGILAVSEDVKYVFFTPSDAPSGSSPTLTVPVADITNLQQTPATAANIALKLVVGADSHVFTFKHPQRAREEQVETTAPLREALAIIKARENALPVAGSSASGAGTPAPSGDNGGQSAAMAIAKAVSSNKADDAWYDDAKLKADIKLQKSLIDSNPALSDRFNQALKDKPESLSITQFTAQFWSARLHLLRAHAIELAQKQGEYNVLPTIGYETKPAEKPGEPDTKTFKITKEQIKLMFKQYPVIKEAYDESVPPLTPTQFWTQLFAPSRLLKKLRGEKVMQNDPRNPVLDKFLDRPESGVMTMTHVPHWMDLEGNEQDHSQRKGNRADQEMRPSGNEKVPILRVLNNLSEKMMSHISTEDGEAHGPIGVDEETYEQLRIQDLVRQDVDNRLVLNVKKQQVYTGGRMEDLSIQARLFAQQDPEQVLSSIRDDMQPSHLGSDKRGTLKLDRVLGYHTDDDSDSDDDTSPHTNGSTTKQKPTIRVGSHKGLALATNNLLSSVRQARRATSGDPHFLNGLSQKTFDTLTMTHDTTTEFLHYFWTVFLSGDASRTRELEQLVATLDRSIDRINAVGDEAEKELQARIADVKREDQIYYERSKKRRRRNFEEYPGGKKAVDAMVGPTRAALGRAVEAYARERDRQMKENAAATGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIE7</accession>
    <name>A0A9Q8LIE7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762075.1">
        <property type="nucleotide sequence ID" value="XM_047904620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIE7"/>
    <dbReference type="GeneID" id="71985350"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05472"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="24816" checksum="5E5E4A5121C132E9" modified="2023-09-13" version="1">MNRSGRSYSSAYGRPSAANFLWTSSTSSISDFSVAYCATGCALNTSSGGLSKADDSSCKEFSVSTTYLRAYDYDPEASPITNDQQRAPLEHTLRYIEHVAAQGGRPRVSATKLAYIKLLERADDLRTFPTFSALPAVVRMRIYGLAMQPNAATEGMDAVPQPPISMVSRLLRYETLPLFYQNQKIGVQLRHQGPTPQLPNGGFIMDQRIARYLASQARESLMRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIM7</accession>
    <name>A0A9Q8LIM7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762468.1">
        <property type="nucleotide sequence ID" value="XM_047905641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIM7"/>
    <dbReference type="GeneID" id="71986371"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06493"/>
    <dbReference type="OMA" id="FTEGYQL"/>
    <dbReference type="OrthoDB" id="5244050at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71982115"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
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        <location>
            <begin position="183"/>
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        </location>
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        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="527" mass="60133" checksum="A0204DB87B800563" modified="2023-09-13" version="1">MGPLSIVLLQMTTKQPLLSILEKLIAEPTREPQRAEGVPNPLDYEAGGSVDQGNAAGYSIESGAEDYVPQFENSNTQYRDEPGTGQNPDGTWQEFDNAQPEEHVDPQQLREQRYFTFEYEAEEDYTAGPVRLVAAHDGVQDCIALLMKLGLSAKIQRAVQTRRSCVREQEYVETHDEEAERFRSSIDEEIDNYNVRVAEADEKQREDPSPENEEELRSLQTKLDVLKHMMANVESKQRQAERGLENKQRLFHNALEDILPELEEAFTWGQLVPFQDEEASRAVEHFDFQQAYEAAWKEMQGLQDDDTGDTHQQMPEPLETGDDFLKPQLPALTPEQQAQREIGQQLWDSRDRFTAAQRRFDHRDMEREYDRANIAGPHLEANQAAYATTDEFDLVWAKRYQEITQELREAEDAFNAAKETAVRAGVLQYGMTSSLADEPDYDAYPLSAENDDPAIAAAQSSSRILDWRAKLRPEGGPDKMKFPVDFERWDDEDIEPNDSVSCVAFEPYRGYIDGYGRQLACLRQGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2Z7</accession>
    <name>A0A9Q8P2Z7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00313</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755645.1">
        <property type="nucleotide sequence ID" value="XM_047899461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2Z7"/>
    <dbReference type="GeneID" id="71980191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00313"/>
    <dbReference type="OMA" id="SWVGMRE"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="32047" checksum="5D8B258751B9E65C" modified="2023-09-13" version="1">MDPFGAEGELVNIHTAFIQGQYTSVLNDFDASSFSESNALPIRILQYRAQCALGQHQEVISAISDSDAKSAPDLAAAKLYASYLHSPSDSLVSSAETLAEQASDNLHVQVLIGTVLARAGKPDQALALLANHQGSLDAVALIIQIHLSQTRVDLALKEARSARSFAQDALLVNLAESWIGLRQGGENYQKAFYVFEELAQGPSSASATSLIAQAVSELHMGRVEEAETALGQASALEPEHVEGIANDLVLKTIVGKETGDLVAKLQTVEKEHELLRELAVKREQFQAAMGKYNPKFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P459</accession>
    <name>A0A9Q8P459_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757101.1">
        <property type="nucleotide sequence ID" value="XM_047900803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P459"/>
    <dbReference type="GeneID" id="71981533"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01655"/>
    <dbReference type="OMA" id="HYDCLMA"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="55208" checksum="FB68DA114D5726C7" modified="2023-09-13" version="1">MPSYGGITVLLQTQYDALPIPEYAPPPQTTSPSVSDTRPSGYIQTAASLSSSHGSTTRPGILRAPHTPCASSNASITSGTSTVASPADRNASRTSLLSRSSTLRSLCSGPSIVTETLSQEPSVESFVPIYYGAQFWIHYDCLMAQHRDERLFEDEQHDEVKYYYFKVFIGGRCVSSWGVGGKDGWRGKVSFGIFNGGTDFEGNDTVERKAFFFPRKHRGCRDVHGGQFDIRVYRSKARKREPLTLPKYEDKASKGGGFDVLDAGRVRRSDPKRMYTYALIDPIDEPYATFRYHLRSIAQLTDMGIDLGAYKASFYASSPPQSPRSLSPVSSPQLSSPAPAIARDELSSYRLSFPPRMQLTASTSSCSRGSPIKRNAFHGAELQRHDYENVMHRPSEDEAPQSLDEALERFDRLSMLDQFMKVNDLRDPAVGHQRFDSMDMVDQNLYGTLPAADIPDWVMSKPLPAPPDNVAPIEGQAAGQNKVGALASLRGFMGSRSKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4C1</accession>
    <name>A0A9Q8P4C1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757070.1">
        <property type="nucleotide sequence ID" value="XM_047901054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4C1"/>
    <dbReference type="GeneID" id="71981784"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01906"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="775" mass="82844" checksum="8806BA4B2ACF5C9C" modified="2023-09-13" version="1">MSWQTSVYQRRVCPILLNGHVVKVTNQQVLDLDCHAADVTVNIRSDAALLSCQFFVMFSPHDLLMLTRMSKISTSAISRRTNANAQKGLPRALLSIAALSVNVAMNPHVGRNNRADLEILEQAVRLTKPWIEAMLEEILQHFPSLAIHDSRPAARRPKSLQDKGLLGVLLSLLSAFWKVSGLLKSGNGVPRQARVLRRLHSVLSTELASAEREIERLKALVGGKPHARRRRQGTKNTGTEDEWEDVAAVDASGEAAGSNRREGTAVEDDTVLEREEVSADVKSTKTQRQSQSPQRIPTANPPGLDASEKIDHTSRHSDCSGSRRTSRKTLKSAQNSPHSDKSAAGHASPKVDVVTAARQQDKSPETRSSSKDGGPASKATRTDRSSHKSPGKSSKSSKERVDSRVSEPVFHRVDQGSQKPSTKSSAKSHSSQPAKDKELWSPATSRSGTASTHSKRSTVMKEVAPLGVNSVSPQRGRRASPKELTRTHSVEEAADVTTHRERQAVATGSQEAINGQRMAENGVKPTKVVGITGRSHASSRAASEAASPPAPTHATEGSGAPEVGAPLQDNTQKPRSNASSRTSKTSRSKRHSSHAKQDTDVGVQAETGKPAISPSSHHSAKSDKSRRGTPQAPRSLSTGISSPVKSRGKSGSASPGTGKHSTSRSCCASRMSSESSRGAQPEASAPSAHGLSTRRMASRTSSVSLEDAQHGSDNDSASSASASTTKSKRGNQYSQQTTSEEHEVDAAKRLLDLGGAIMLDLWRAVVAIRKRGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4N3</accession>
    <name>A0A9Q8P4N3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757415.1">
        <property type="nucleotide sequence ID" value="XM_047901304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4N3"/>
    <dbReference type="GeneID" id="71982034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02156"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="266" mass="29913" checksum="C1AE786CCA81EF0C" modified="2023-09-13" version="1">MGTMNHSPLLRLSAELRNVIYEHTFTSQYAVTLCSGKVQHPLTKTCRQIRHETLPMYYAVTKFNAHLDDGPATPLAKWLKTQAPELVLCMNGLVIWSWISGFARILLDDDNMRNLNYTLHGTESTSLLLETQPAQGKHYTLRPVGSWILEGGFHLKEICIALQEIGLSLSRFCITDETGDSRFRLTSEFAIVALNPVPVDLAATDDHIGVNEAARQIGLSDCARGELIQRVANGHRRVRLVDGRRVLMFQFAGDRGIWLQDVKEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P572</accession>
    <name>A0A9Q8P572_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cutinase transcription factor 1 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03216</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757957.1">
        <property type="nucleotide sequence ID" value="XM_047902364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P572"/>
    <dbReference type="GeneID" id="71983094"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03216"/>
    <dbReference type="OrthoDB" id="5121955at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="770" mass="86128" checksum="37A86B0FB4625518" modified="2023-09-13" version="1">MTAIAVNGSEPQAMHTDDTILLSPGANARGKLKQRRSRKACQHCHTRKIRCNVLENGTPCSNCVDAGTTCIIRRRKNQRRESTPPDQNGHHAVIDQSHSWRLPTPSGWPDNTAQRPSLPPRAPSQSSAPYTAQNGTSIENGSQSSASPDTGQLWTVDTGAGLAWDQNALVDASSASCDFSHLTDLDDIFTFTGNTLLPPIPQQHDYAAWHQPLTQQNLSPPPILPSPGVNVVNGAGNVGPRRASFVPTSVHIPGLNPRDHEYLRGEGCFDLPPATVLRQMMHMYFRMNHPNLPIVAEDQFWALWSGDEYRVGEYSYLLLRAMIFAATSYTEPEVLSTIGFVSKREARNTHYRQAKLLFDFGIERDPVCSAQACLLLSYNAPNYNIMRLNTYWVTNAMRFARIARADFYDKIRDPVRSKLLKRLWWGVIFRDRILSMGLRRSLQVELEPAWAEGDKHVITALDFQNELGKSPVHDTETQLRVVEVVGATCRLMQCLTNAGLILYRYEHLDDRLDNVGKSIPQTIQDIKRCLETLRHWHDHAIRLFPFPVSLDDAPETICVYANMMFSYHAAAVFGLNTYLILIREVFSQAKALFSLEEAHEALQVANTDVSRRTQELVQVRLVKYLPISASAVLALPLILQAINVSAARGSGMEAVERRRLDVFTRTLKSQQQSFDGSDFCADALANIVAYAQDDSKFVSSMTTWRDGKDTHGGNAANGNGAHKVRLDWGNLVYKRPRLFLRLVLYLDHAFSTGGPPGDDDFPEVLQKSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5A1</accession>
    <name>A0A9Q8P5A1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS efflux pump atnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758032.1">
        <property type="nucleotide sequence ID" value="XM_047902499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5A1"/>
    <dbReference type="GeneID" id="71983229"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03351"/>
    <dbReference type="OMA" id="FFITTSM"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="535" mass="57327" checksum="CA86E6640AA79D58" modified="2023-09-13" version="1">MTLKDEERQPLLSAQPVQSATETLPEDDEKASRWRSIFPKIEVTDSRFRFLPLIGCLTVLLNEGEYYFKQIGYFRAIEALYCIEYFQSHDPAVAHLGKGIPENMCKLDSIQKKVATANGIVMLVRMTSSFIGTMIVGYLADKYGRRLALILHKVGTIIYTLVVCSTYLGYPYVPIWVSFCGGLGGLIGANFDLNLAVLLAAYNDALVSSTQVATYFFITTSMQYVGQVSFPLLAGKAINLDGKGGTSELSLFTSLGMAFAGLVISVLFFPETMKKPEQADIPGGGDTDECTKRKGVSAVIAAKAKSLGEGFQQSVQGVGATNVILLLVAMFLATTAIKAVDWLGLIQYPVIKFGWKYNQSTFAMAFQAVVYIFTYFALLPTYNKLGARYALSPSSTSLLVMLLSVTLLIAGSIFLGLSATPPHFVAATCIYTLGAGMPAVMQAYIANLVQKSSLGRLLAIVSLFQVGGKMAASALGPIIINAGIDSGNDNLKGAVFFFAAIVFACSASALGVVALRAGVTTDRAEDMGVVDDNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5E1</accession>
    <name>A0A9Q8P5E1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758391.1">
        <property type="nucleotide sequence ID" value="XM_047901651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5E1"/>
    <dbReference type="GeneID" id="71982381"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02503"/>
    <dbReference type="OrthoDB" id="3643927at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="26690" checksum="EB29CD82148C6D76" modified="2023-09-13" version="1">MCSSFHPSEPKPHALLPPLQRHIMDDSAQTEQEVDPGATIAADNLEKLGSIIEEELKSWMIYLHSQSGAPSYEILTSDDKTDAATKIKCLRHILETLPTRHKALINAYNAAETEQVELADQCAVLLEQLQVAAEVPPNESKAAGDEDNKKLDLQGYYDQKLFRGKKFKADIAARLEELKELMTMFEELMIVREEGVLELKQVQLLVEAMDDVGLSASSALVGEESTQVKKARVVEDGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5N6</accession>
    <name>A0A9Q8P5N6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758676.1">
        <property type="nucleotide sequence ID" value="XM_047902170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5N6"/>
    <dbReference type="GeneID" id="71982900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03022"/>
    <dbReference type="OrthoDB" id="10479862at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="16669" checksum="F4AF9205A9B2CFB0" modified="2023-09-13" version="1">MNTPPYTPQTSTPQYAPTHRNDTSLNHELIITHLIDAIILRSWALDDDLAHALERVLTTVTGENQKTQDRFDAAVVEIQLTNEDNYRWISLMKVGEALGLVPFVPDFAVHQARLREVWRAMYGRDLELALKSGVVDLARRALGEGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5U2</accession>
    <name>A0A9Q8P5U2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase TARBP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758841.1">
        <property type="nucleotide sequence ID" value="XM_047902150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5U2"/>
    <dbReference type="GeneID" id="71982880"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03002"/>
    <dbReference type="OrthoDB" id="241340at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18091">
        <property type="entry name" value="SpoU-like_TRM3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045330">
        <property type="entry name" value="TRM3/TARBP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044748">
        <property type="entry name" value="Trm3/TARBP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029:SF11">
        <property type="entry name" value="METHYLTRANSFERASE TARBP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029">
        <property type="entry name" value="RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1260" mass="139633" checksum="81FC56AD0C5721F1" modified="2023-09-13" version="1">MRAVSKILLRSRSLHLPRSTIFAAKFSYMSALRSSTARLLLERVKEDERSHVVQQLASSLDEESGRADVDLTATLLGLHHDDAAHKVLLSRLQRLIERGDYDQVAAVCNDHHVLLQAVCVSASKDVSDLAEGVQGSRSKWIAVATSPRAVKGQRNGMTGENDETMTVAITRTVQILHFLNRVGFTSIADDEIRSLLESCYVLVGASDKGLYTAAQETISSMLGMRRSLSFNEQHKLWQCIRHLARSTDVTYETIGFSLWLRWISSSPNIDARIFSDQEYWDLTVSGLRYGDSERRKAALQILKTSVGMCVQDPALISAITSNGDHVPAPSAVADQYARYSTVFETIILGRYLNQVMECEADLDFLSSSQSVVNPVWLYTLLTCAFNPKLQESNRKYIGTWIMASKPRLDDVDVYLDFFRQAFLPWVTGGHMFTSTLHREGELTCCEHGDRLALYIAELLQNTSAVANGVVDAILESVLSRQANNFAYAIAYLVEGIRQAYLASDKLVLSTAQLESIARIPTWAGLPEVSRDYILATSWNLSHHYVQRHGEQAATKPVTSSARKWQEVLERATALPLEASAHVHGNIASMALVQSNRDRNEGDAIQKVVTAVAQLESADQSNDALRLKEMLEDVFESADYLEYPMSLLTVLPMLVPHRRLVELALAESATTSGLDELLTEKVSRLLELAQKRAYLLAPIVTAVRDASLQIPNSSAMLRLDQAVIGLAEHPPGLTIDARLEDAIIPLLQGLDPGMTRFDHSFYFGPRQSYGYAALLDLVSRLGAVDRRVIQQVAETILERWSTQKVPAPSVSPWKTGLQLQVLLLALEQYLPYVDHEEAMSVVSDLYHNLSVEPLPKYRYLLEWMIARAYIHHPGLKNGILDHLRTKDHHSNPKFLASLMKLGVTLAKVEGSTEAFAFDLAALFVPMAASSKVVIRHEAQWSVPNLMDLARERKWATITSNTALTELDAYIRSLERFGDPPLERQIDKLDPVKDHTLTHLVEGPWYELDHVEQRQTSREDFVALYAKDPASLPPSCMPLGDPIPSARSTTPSAKSSILPKTKDDKISRNITTITNALTSTSLSTSTTALQTKGAAYLSSTRTRHTTLLVIASLVDNPYNLGGISRASEIFGAGTFFVPSTNVLSNKDFTSTSVSSHFHFPILPLPASDLATFLATKKREEGYKVVGIEQTDRSVILGEKECVLPEKCVLVLGSEREGIPAQVLGECDVLVEIRQVGITRSLNVQTAAGIVLCEYGRQHAKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P778</accession>
    <name>A0A9Q8P778_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04546</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760236.1">
        <property type="nucleotide sequence ID" value="XM_047903694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P778"/>
    <dbReference type="GeneID" id="71984424"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04546"/>
    <dbReference type="OMA" id="CFYIHGG"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="17"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="61732" checksum="26B7D0FD38B58CC6" modified="2023-09-13" version="1">MPQEQARSESYLIEAGSLGCIEGATLSSPTDSKVLCHYFGGLPYALPPVGPYRFRQARPLPHHYRYGTRSNPGRFSARAAVCPQPGFMGPADESMWDENCLQLNIYIPSGSAPKEGWPVYVYIHGGFLQWGSPNMPPEALAPLFGETSFNAIMVAPAYRVNALGFLASRELQAEATLLGEPTGNQGFWDQRLALEWTSNNIAAFGGDRDNITIGGYSAGSHSTFQQLAHELYFVPDHKAVIKRAIMWSNSPGVQPKTLPEHQKQFDELLTTLDIPLTLSASEKLERLRRVNSHDLISAQGKLKLHEFRALSDGHFISKDMIASINNADFARRMKARGIKLMNGECRDEHHLYQAWRSPSASYEAVFTRLCADYPEHVVRQLMAKRCGPERRLPAGSKDWPDAFGRLYADMQVHGLERGFHRALVNGGLEPGKDLLRYRFDWRTKGTEVIYPLAWGVTHATDMSIWFWGLDGGLLEEEKQILRPWNQAFSAFVKGDSLDWGTRDVREMRRLRADGVTDIWTDDRWNDVEVWDAVNGHAGSGILGWIRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7M5</accession>
    <name>A0A9Q8P7M5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760640.1">
        <property type="nucleotide sequence ID" value="XM_047904392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7M5"/>
    <dbReference type="GeneID" id="71985122"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05244"/>
    <dbReference type="OrthoDB" id="10655631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="67196" checksum="792B20FB9E242655" modified="2023-09-13" version="1">MAAESLGRHCVACHKLKKGCDGANPCEYCSHKGIACVEYIRKKVKRATLQNEMGEHGEMRRRGQANKRRKTGHTPGRLPRRHKPGEAEEVLEENMQETPMIFEDTRWTLRAKLNYTQHVKYSCCTKILTTLWLVDEDGEAVKIGELKSAIINKTDDTWILELLNPKSCSRALLSKHEVGGRARVGEMRRVLQMIFDEQGHVRDIEELQRDIYHLTGDKIHYVSVFKLEPALRSAGLGVAAMTLYHKALTSGQGNLPFEGYSVLSPAALIDEYETYEKRVIAAGGMPKSYLQVEDALINFYAKMLYYTLVLGDRKQDARAITVVARPITEELARLELDLLKERMKARLPLQDAVLATRDEDTSVERIRRAHGRVVARLVRTAEAERQYHVEMKDFGDTVDTVTSADSFKDIDGGADVSQLQDLVNHLKSARSISMQQIFQRLNLSVTQLRDLQNHIQSGRAQRTAALIRQGMLKLRRPPRNATTNSQNQERDAEKDASAQTYTQSDAGRQIAQALETFSMSTTPPPKMPSERERASMVLQSRTGDGTDGEDITVVEPEGQVEGTAVVIADSGTAVAERDTGEQGEQIDGPTGGVQLEEGDKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7P5</accession>
    <name>A0A9Q8P7P5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760609.1">
        <property type="nucleotide sequence ID" value="XM_047904335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7P5"/>
    <dbReference type="GeneID" id="71985065"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05187"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="33915" checksum="DC9CE6EAAA4978E6" modified="2023-09-13" version="1">MFVSMITSGSTIAKEIMGGMQSVNGTFEIGATLCMPGGNDTAPEQVQILTHGVGFDRNVYSDFAPGYSYVDVAAQYNHATFYDRLGVGKSAKPDPINTVQSPLEAEIANSLAKSLRQGAFSGIAFKKVIGAGHSFGSIITQAITAQYPATLDAAILTGFSTNSTGMPPFLQGLNLAIASQNSPYRFADLNNGYIVSSSAIPNQIEFFRAPGFDPAILYQAEAQKGTVTLGELLTTSAVMAPAMNWTKPVAVVNGAEDLPFCLGNCSYPTNKAQAVFAMLYPATNTTGAYLSEVAGHGLNLHYSAVEAYHYIQDFIGKNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA60</accession>
    <name>A0A9Q8PA60_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA ligase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06928</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763077.1">
        <property type="nucleotide sequence ID" value="XM_047906076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA60"/>
    <dbReference type="GeneID" id="71986806"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06928"/>
    <dbReference type="OMA" id="RIDEFWR"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="397"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="694"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="794"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="996" mass="112978" checksum="C6F1CF94C9C15681" modified="2023-09-13" version="1">MPFPFIETCTLLNNLERLETCDAPLLGPAKYSKSKELIESWFKSHRRKIIELSEDGQTALLSTLLPEWRTDRVYGIQTQSLYRMLSRTLGLGTARLKDLEAYKQPGFGDLPACLERVLRAGGTPAHPPVQLEEVDDMLGTLASGSIFSDPSIPRLPRSSSEMRDPVIARLLKRVRPDEGKWLARLILKDFSPVRLDEFFILKNFHFLLPDLLRFQRSFRSAVGLLKGELSEYHAQPDPRSQRLFRLQASQRMRPTVNTKVGRPTFHKARGIEHCLNMLGSQEWVIERKYDGEYCEVHVELLHAPDWKKCIKIYAKSGKDATADRAGLHETLISSLRLGDAKCRFKRRAIFLGELVVYSDEEDRVMPFDEIRKHVTRSGVRLGADADSQPRACEHLAIVFFDILLLDDEIVMNRPVEERRQWLRETYRKIHGRALGAEWKKIDFTDREYGRRKLIEQFGHAIGRRCEGLVLKPCGVPYFSLDASPDDFKHSFIKLKKDYIDGMGDEADFAVIGASYVAQKAAATTSTASRYTSFHLGCLTNKDDVRRVNARPIYKYVWTVDHEKCIPKPVLEAANIVARFAGKPYTPGVAPQKFNIDSHITLKMDVVFDEPFVVEVLGSGFDKPSNCRFLMLRHARVKKLHEDRTWMECVTFQELQQQGDAARSAPADSELQDTLRWIAKLEASSKRTFERERSMSMTPRYTRSRTSLTPLRASISAASVSGRVKSPGHQHPGVDGLPTPLPSSAAQPTTTSPNQTRCRKRALEGPQTHTVAKRVRADHSTTSAEASRLTPPVSSPLNDITNTANGSPTREPARHAPRSSALTNIVNKVVTLVQPTRPTTTQLSKTHLCENSTCAFSNTTIYLAPCIASTLYITEDLLSTHAVAMTPTLSHWDRNSFSHDPLTDTVSESQSHPGMRKIVLVEHKRRTATRALVQIVLQLNDGRFKERVEVWDWRMLEECQGHDRPVDRVKKYFLGATIWDEGRRRAMFVSGCEWLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAK3</accession>
    <name>A0A9Q8PAK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pisatin demethylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763268.1">
        <property type="nucleotide sequence ID" value="XM_047906478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAK3"/>
    <dbReference type="GeneID" id="71987208"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07330"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="137"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="34055" checksum="61C005EEBE1F54DF" modified="2023-09-13" version="1">MAFDLALEGRQASDGGSRFGKVGIFPELHLPLFSTVQALGIRNAGTVIEPAVRKALAKYRNVDFVEKENRKADCFMNKLMKLEEEGKVNLENQMDCIGGNLAAGTDTTGITISACLYYLYHNPHILQKLRDEIDGATQEGTASDPIPRRESRLPPMCHSRNSPHPPCSRLHLAARSPSRGHGTRRNILPSRHPRRRLRLGPKLQPRRLRSRRPRLQLRPYMDQFGSAKNAAAQMGNSFSFGGGSRTCIGKNVSLLEMTKVVPQIVRKFEFVFADEGREWKVWSSWFVFQEYWCYVKEREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAZ6</accession>
    <name>A0A9Q8PAZ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763478.1">
        <property type="nucleotide sequence ID" value="XM_047906394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAZ6"/>
    <dbReference type="GeneID" id="71987124"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07246"/>
    <dbReference type="OMA" id="RMVMIAN"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="134"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="49295" checksum="DEC0A04A2C0F7563" modified="2023-09-13" version="1">MDGLKQRKPAPQSTTIPANVQNGSIQHRDSHPLGAPKHGGGMQALRIVAFGIYFTISCLVMHGAQLLGIPLYWINRDWFYAWMAMTKQFFGIFITTMTNWWSPTVVRVSGDQSVAGLLKQDASGIVSLDFGDRAVLMANHQLYTDWLYLWWSAYTNTLPMHGHLYIILKDSLKWVPLIGPAMQLFGFIFMSRKWANDQERMRYRLQKLNSRHSGPMSGQSGKAQLDPMWLMIFPEGTNLSRNTREQSSKYAEKAGLQDMKHQILPRSTGLQFCLSELRGTVEYLYDCTIGYEGIPPGFYGSELFTLRSVYFQGRSPKSVNMHWRRYRIKDLPLDDHDKMYEWIMARWREKDELMDTFIRTGKFPADKSAVEIEGGPTDSFKTPYINTEVQPSSPTEFLQMFMPVAAAAVVGRVLVQIMDRIFPSPALMKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB01</accession>
    <name>A0A9Q8PB01_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase atnD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763526.1">
        <property type="nucleotide sequence ID" value="XM_047906411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB01"/>
    <dbReference type="GeneID" id="71987141"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07263"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="36743" checksum="C7FA285ED193B023" modified="2023-09-13" version="1">MQALKIAGFLPTLMTSQFFVNIPIPEFDFSGQTVIVTGSNTGLGKEAARHLVRLKASKVILAVRTVSKGEAAAKDIVESCKVSADVVEVWELDSGDEASIDAFAKRVQALERLDAAILNAGVMTMEWRTVDVHESTLAVNVFGNLRLTKVLLPKMQDSARRTGQQGRISVVGSDMMYVANLGELETDGKIVDKLDSKDLSLKWMGQRYQLSKILIFWAMKQLAKVNPVAGESGVVLTVMTPGACKSTIFRDPINPRVKNMADWVMALFQRTTEVGGRALVHAIEPQLPQEAHGKFLMDARVGSEGLNVTSKQAERLAAKWNEEVLAVVEDHGNPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB11</accession>
    <name>A0A9Q8PB11_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_07541</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763541.1">
        <property type="nucleotide sequence ID" value="XM_047906689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB11"/>
    <dbReference type="GeneID" id="71987419"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07541"/>
    <dbReference type="OrthoDB" id="2018833at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000006">
        <property type="entry name" value="Phosphoribosylamine--glycine ligase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000006">
        <property type="entry name" value="phosphoribosylamine--glycine ligase, chloroplastic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000018">
        <property type="entry name" value="Trifunctional purine biosynthetic protein adenosine-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.600.10:FF:000001">
        <property type="entry name" value="Trifunctional purine biosynthetic protein adenosine-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="entry name" value="Phosphoribosylglycinamide synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINE--GLYCINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01209">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="116"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO19175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="433" mass="46729" checksum="D732F182E88FD247" modified="2023-09-13" version="1">MAEQLRILLIGNGGREHTLAWKLSQSPLVQEIHVVPGNGGTAGVLKCRNVSSVSQEDFVALIEYAKKNHLNFVVPGPEAPLVAGITDVFEQHLPNVRVFGPSLAAAKMEGSKTFSKDFMKKHNIPTARYENFDNYDAAKQHLNKVDYTVVIKADGLAAGKGVIIPATKEEAQSALKEIMLDKEFGNAGNSVVIEEFLEGDEISILSLSDGNNILSLPPAQDHKRIFDNDQGPNTGGMGTYAPAPIATKEVLDEIDRAVLKPTIDGMRADGMPFIGCLFSGFMLTKNGPKLLEYNVRFGDPESQSCLPLLKSDLAELMLACTNGSLSSQKLDIRPESACTVVLAAGGYPGSYAKGISMQVAEEKESEGRYIFHAGTALKDGQLVTNGGRVIAATATGSTLQEAVKKAYEGVEYIKFEGRQFRKDIAGRALRQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBB2</accession>
    <name>A0A9Q8PBB2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763656.1">
        <property type="nucleotide sequence ID" value="XM_047905881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBB2"/>
    <dbReference type="GeneID" id="71986611"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06733"/>
    <dbReference type="OrthoDB" id="3637982at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22824" checksum="138CB252D9AFCF59" modified="2023-09-13" version="1">MAIMTPAHPSQELTCTKTSNKAPSSAVAQVFAIPELLEHILIQLGLDAYNKAPELQEPAKELFTLQRISRTFQAVVAESPRLQSLMCLSEDTAYPQYRHAGFTWLIMRVYNVSIVYEEQDGPWGKVTLAKSKPYLATSYWVDQQFDRRRRWEAQRWKPSWHRMIAAPVKVEHQCVSFSVEEACTLWELVDRYRYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBD1</accession>
    <name>A0A9Q8PBD1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763687.1">
        <property type="nucleotide sequence ID" value="XM_047906530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBD1"/>
    <dbReference type="GeneID" id="71987260"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07382"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10660" checksum="77F22AD2D7757326" modified="2023-09-13" version="1">MVTVSSLWQSPAINPVNQKARSIPVLNPVNKYGRVFFFSWWGFFIAFWSWYAFPPLLSITIKQDLELSTVQIANSNIAALTGTLLVRFVAGPLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC43</accession>
    <name>A0A9Q8PC43_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764109.1">
        <property type="nucleotide sequence ID" value="XM_047909866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC43"/>
    <dbReference type="GeneID" id="71990596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10718"/>
    <dbReference type="OMA" id="DCPEAYT"/>
    <dbReference type="OrthoDB" id="2014333at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10230" checksum="2C620471EA1D15A9" modified="2023-09-13" version="1">MTRAQQQISLGLLATALYSIFFLGFLPIPDVFQNEIIPVLPFWALVSFGAYLLGTLGYGVLTFNDVPQAHDELMKQIEQARTDLKKKGVSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD64</accession>
    <name>A0A9Q8PD64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764665.1">
        <property type="nucleotide sequence ID" value="XM_047909179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD64"/>
    <dbReference type="GeneID" id="71989909"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10031"/>
    <dbReference type="OrthoDB" id="10480763at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="20859" checksum="2F1DF3172AD5A026" modified="2023-09-13" version="1">MCEPSAIRYRETLPLYYCSVTFCLDHKGHRDYSATDGTFYRWLQRNSTEDLQRIRYLELSIRVPFIPPAKTGATKDPSVATINIDLSVTNPDRAVEYLDYYSDCPLMTKPLVRKAIAKIPRVEKKPLVTREVLWDIWEACYFLSRSDPRERRTWPTSAGHMSSTRAKTTLSDGPRMSTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD68</accession>
    <name>A0A9Q8PD68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sugar transporter STL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10275</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764742.1">
        <property type="nucleotide sequence ID" value="XM_047909423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD68"/>
    <dbReference type="GeneID" id="71990153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10275"/>
    <dbReference type="OMA" id="NCATIPA"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="45"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO20376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="640" mass="71263" checksum="6F57D8B7C91293F8" modified="2023-09-13" version="1">MSERSYSISHQVTGGSSGEQRQIVVEIPNMTPYMGLRGRPLSQLIGVVSGMVFFLYGYDQGNMGGFLTIRSFLEQFKPIDPGADYSAPGTTLLHISQLEGFTVAIWNLGCLVAAVIAIFIGDRLGRKKMIGMGLVLLLVGQILQASSFQWAQFLVGRFVAGLGNGFNCATIPAWQAECTKAHRRGTVLMLTAGCCLAAGLSFAYWMDFAFAWLDPNDAAWRAPIGIQIIAIVAAGGILYFMPESPRWLILKGREHHALEVLAALNDQEPTAQEVRQEFLQIKDAVIEMIKGASKFTNVFKMGDYRDFHRVLLAVGLQFFQQIGGINFMTQYYAQMFNFQYQTVPWVARLLAGCAGTEFFLASFISVWVIDRFCGRRTLLMIGTFGMTISMITLSICLSINTRASLNAGIVFIFVFCTFFAIGWQGMSWLYQVEIVPLRIRGPANAISTSANWLANFIVVMISPPAFVNITWRTYLIFVATNTTILPIIYFFYPDTSNRCLEEVDVIFFAANSSKHPWLDVKQIAANEPLWYSGTDEDARYDYEQTEWHQRHVRFSDEVKDSEGDSTTLRNASDSEGTEKGLNGSDSSEMGLPLPAVVRGRSGSGSGNEARPVVSRGSDTARTREYENRNTRDAVLPHFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDC3</accession>
    <name>A0A9Q8PDC3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764840.1">
        <property type="nucleotide sequence ID" value="XM_047909544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDC3"/>
    <dbReference type="GeneID" id="71990274"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10396"/>
    <dbReference type="OMA" id="PATPRCY"/>
    <dbReference type="OrthoDB" id="5354320at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF25">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="163"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="54403" checksum="41DC613E665CEFE9" modified="2023-09-13" version="1">MEAGWPLIKFLFPQVPSMSWAATQNALGLTDTSKFWDTRTAVTVHVLRSLMSSEGKKEIPSISKIQKGTLRDPGVKGKTWVATATIAKPPQEEGDLREAIFAAVDAMKKEEVTYTKPECEDIEVEWTGHKPNAANGEPLPDISEEEKYKRMMAEPTRTSETTMLYFHGGAYYLCDPRTHRALTSRLAKESNGRVCSVRYRLAPQTAFPGQLIDALMVYLSLLYPPPGSMHAAVPAEHIVLGGDSAGGNLSFGLLQLLLQMQRSASGAVPVVRFRGRDVHVPLPAGVSANSGWFDISRAMPSLEHNAKYDYLPPATHDDAVSRFPKDSIWPTTPPRGDLFCDLSLLDHPLASLVLAESWENSPPLWMCTGYEMLADEDCLVASRAAQQGVKVQFEQYEAMPHCFAMLIPHLESSNACVRNWGDWARRCVETPGQMGTSGRLVHARPGKEDQRVDVERMPSVNYDEAWGLVKAAKLKRLVGWEKEGKGMPKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDN0</accession>
    <name>A0A9Q8PDN0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765005.1">
        <property type="nucleotide sequence ID" value="XM_047910141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDN0"/>
    <dbReference type="GeneID" id="71990871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10993"/>
    <dbReference type="OMA" id="DTHLIVC"/>
    <dbReference type="OrthoDB" id="5391496at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="243" mass="26964" checksum="D3A7F139ABE67DEF" modified="2023-09-13" version="1">MAAQGPVVFETKSIQDFIRYVLAHHKPPSTLVVCSSKEPFLHALQLEARSVPSPTDNRNNDTTVDEATLAKHLLHTPTLRLLSTARTLKLAFCQDITHLRAYLATYSNSITNRHMEIDTALRQPDVRPVLAILSPVQLHRSTSTFSAQGLNCTFSVAVEAAHQTGSRLVMAEIAYQSTNTEDEADLRTPPSNITPHPWDEEVSILNVTTKRLGELSSGRIVKIKAIASRWCDFQELPTLEGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDT6</accession>
    <name>A0A9Q8PDT6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764966.1">
        <property type="nucleotide sequence ID" value="XM_047910482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDT6"/>
    <dbReference type="GeneID" id="71991212"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11334"/>
    <dbReference type="OrthoDB" id="5394701at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47691">
        <property type="entry name" value="REGULATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="49661" checksum="DB7D3C90BE1B10EF" modified="2023-09-13" version="1">MLVLVPNKLWPGSDKGSIFWNLAGGLVWLQHNHTGQMSQPAGANYSNFNVSDQARVHAGDNYITLPAPAKPSPRSLVPQFFSRDKSFIGREDIIKDLESRLANDDYHNRIALTGLGGIGKSQIALEFASHYSKRHPGHWVFWVSASSKSRFVQDMEEIAALLGMPATTDRQGTLKSVCRCLSDPQNGTWLMIIDNADAEDQFGLYYDKDTIRRWFSLANCLLFVCQPAATEQILNRLTVILDIMGELYPDHASLVLYHTVVDMLVDVRVARNKELGSMLPLLDAFPAAQHSSNTSSVINRVLVDVDVLMRAGNVRGAVRYLEPRVHKLACVIAGNRICEKLIQCYCMLGEYAKAEAFAEDIQQSKRNSRRSDLNIRYHRQLNLSEIRRWQGRNEEAVDIMRHALKELERAGEDPAGATAVQRRWLLNIYLAKARASNDKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEA6</accession>
    <name>A0A9Q8PEA6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">General transcription and DNA repair factor IIH subunit TFB4</fullName>
            <shortName evidence="14">TFIIH subunit TFB4</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">RNA polymerase II transcription factor B subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_11527</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the TFB4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765235.1">
        <property type="nucleotide sequence ID" value="XM_047910675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEA6"/>
    <dbReference type="GeneID" id="71991405"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11527"/>
    <dbReference type="OMA" id="QGCDITS"/>
    <dbReference type="OrthoDB" id="17307at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO20869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="380" mass="40753" checksum="72FFE651AF613F90" modified="2023-09-13" version="1">MNAVDATERSDKHDETEPPSLLTIILDTNPHAWALHETSLSLSKAVANLLVFINAHLAINHGNKVAVLASHAERAEFLYPAPARVKQHPTAATGNVDTGNDDLIGSGGPVQPPDDANKYRPFAHIEHALTSNLREMMNRTSPTSLSAPSTMLAGALTMALTYISKQSASLPTANSSAQFNYSDPSSVAGGTDLTADGRKKKHHGLRSRILILSVSGDLADQYISIMNAMFACQRMSVPIDILKLAGDTVFLQQAADATGGVYVALDDKTRAGFLQYLMFAYLPDQTARAHLIMPGEGEGVDFRAACFCHRKVVDTGYVCSICLSIFCEPLHDGTCLTCGSHLTMSNYGQNPVVVPKKKKKKKRPLDGATPDSRAGTPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFK7</accession>
    <name>A0A9Q8PFK7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-splicing factor srp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765883.1">
        <property type="nucleotide sequence ID" value="XM_047908537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFK7"/>
    <dbReference type="GeneID" id="71989267"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09389"/>
    <dbReference type="OMA" id="PLIRCDV"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12467">
        <property type="entry name" value="RRM_Srp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000123">
        <property type="entry name" value="Pre-mRNA splicing factor (Srp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034403">
        <property type="entry name" value="Srp1p_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="234" mass="27484" checksum="4BC7319359229117" modified="2023-09-13" version="1">MSRGGGTTLYVTGFGHGTRARDLAFEFERYGRLVRCDIPAPRTASSRLFAFVEYESRRDADDAYHEMHNKRMGRDDVLKIEWARTPPSASWRFDAGSERNRDSRDGGRDGGRGGGRDGARDGGRSDRRERSPRRGRSGSPPRRSRYEDEGTRDRDYDRRDRDRDTRRDRERTRTPEDRDRDRDMKDRDREEEREPEREREYERENGTNGEERKEEREPEEAAAPPAHEDLDTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG52</accession>
    <name>A0A9Q8PG52_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ubiquitin-40S ribosomal protein S27a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09703</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766355.1">
        <property type="nucleotide sequence ID" value="XM_047908851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG52"/>
    <dbReference type="GeneID" id="71989581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09703"/>
    <dbReference type="OMA" id="GVFMAFH"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71989163"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO22035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="381" mass="41753" checksum="38361DF208948DAA" modified="2023-09-13" version="1">MNPATVASRPLITSTISNEAERAALYRRCTGDELKKFVKDRTKSKFQSTGSSFQLDACLHLLQLDQQDLFPFTSLPRDLRLDIEEILLLPQPGERLHSQILATCKTIHVEAQGFLNRAVSSGSIHLLRIRSNQDSDGGPLTSCQKLNCKCKGGPSTTIRHGLSPAGNIRTLRRIDTELAAFCPLNATATRLLIDIRIEAPCVGASLQILRPDPKINRHLYLLATAIQSTAITTVDLRLTCSGYLDPSDAIFMLWPLSCLGPNIALTISSTDSEVVENLRVCQAESGGDTTALSRYLPIKAQADDLIRRVQEARLEKTGVQFLPANLGASFNGSTAYIAVSDIRDRHPAPESCIRDNVTRAANLMANERLKQLAERVNEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHE5</accession>
    <name>A0A9Q8PHE5_PASFU</name>
    <protein>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992065"/>
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    <dbReference type="OrthoDB" id="3629107at2759"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10449" checksum="0DB2FB4849E8A7D4" modified="2023-09-13" version="1">MAPASLYDLVVTGRELQYVAKAANGKLKLTSTSTGPTAHNVNGRELVTTIFTVDCHGQIGIVNEGILYSLKIDLETAALSFSPGLTPQTAVSSHWTSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHL2</accession>
    <name>A0A9Q8PHL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Asnovolin J 5',6'-dehydrogenase nvfM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHL2"/>
    <dbReference type="GeneID" id="71991674"/>
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    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="34467" checksum="4D38FCAB33823CF2" modified="2023-09-13" version="1">MSRIKVGILGASGETGTSIINGLLEAGTFEIIALTRPSSMTKPSNQALASRGVTLREITLSASSNPTTLLPTIRDLQILISSIAPLEQLAQIPLATAAKAAGIQRFIPCAFLPVIPAGGHHLLRDLKQVVYTHLTSLPLPYTIIDVGWWYQISIPKLPSGLTDAFVLSGKSEIAGTGNVPSALTDLRDIGRYVARIIVDDRTLNRYVFVYNEMWSQNEVWDLFEKESGEKVERHYVSEEELVARVESYSLSQNIRGENTPEFAKSLGYLTSKELYPELEFKGLEVFAKEILRGEVPTIYEELKKQFAAWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI33</accession>
    <name>A0A9Q8PI33_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen permease regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767229.1">
        <property type="nucleotide sequence ID" value="XM_047911124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI33"/>
    <dbReference type="GeneID" id="71991854"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11976"/>
    <dbReference type="OMA" id="IVMHKPD"/>
    <dbReference type="OrthoDB" id="338854at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="485" mass="55270" checksum="C618BFBBFD93D499" modified="2023-09-13" version="1">MLRAVFYARFHPERGPSVIHQYPPSSIVSTSRPNDTLIKWSEISAYIIPPYDLCNQPLGICVDRHRVLAFPVSLEHEDYHRNRFTFNICFVLGEDDDATLWDPIVRKTARFLTSAEDDHCFLQQEEKIAGLKWAGDEGYPVDGLGQVHGLLRDVFEGLNTYGECSVRINDANVLNLRLEAARSASPKVRAWDVPLLIRDLPSREVWTWDLTLKRIHTYIDGIKHVQKIAELADVELKLVKRVVKELVYHGRATLLDIFHFQAIYACTETVTVLLNDEELQDECRYYITKSTGATAPHLEGKDLEKDVPPTRQQVVELYTLLHPGLQLHEYCLTHRDRLTGVDTRRLITFGIIKGFLRRVHKLALALEPQHPTSPLAEKKRSGSSTSKSKPRSSEDAAAREYHRAWRRAALTSGWATPPSAPPPAGLGRSYKSADHVRSEEDERLRSYLDGGHCMDQICVEMHMSERKVVERLRSGRLGDVVLFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIM3</accession>
    <name>A0A9Q8PIM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992778"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12900"/>
    <dbReference type="OrthoDB" id="5140754at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="304" mass="34527" checksum="D6C7041B2794A25D" modified="2023-09-13" version="1">MPSNHADASQSFDLPLRGGDGLRQEQSTAIEDALRKYRNRVLEINMAKLETAISDIETREIKAMEFWPKTPKLDPEELPQRRVERLEGDYGVRLEHPQDPSITSIRDFLSEDRRGNLVRSCRLDGVVHGEVDIEALEAWIEKTEEQIRTAERTEIHLDGLPAELKYLMTLIRGICGNGLPAYRYSGQLRQMKFITDIEGEETEGEEPRNSGFVTVPRTDEEMSEGHLGDIQGSWDDHVVALAAGIGNGGFAVYCRKQEDADGAIGWRWKYGLWDPEFKTALYDTVEEFLEFYADFDKEGGDDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJJ7</accession>
    <name>A0A9Q8PJJ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768024.1">
        <property type="nucleotide sequence ID" value="XM_047911938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJJ7"/>
    <dbReference type="GeneID" id="71992668"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12790"/>
    <dbReference type="OMA" id="CNPRTHS"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
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        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="185"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="54758" checksum="487EDB0D7541F920" modified="2023-09-13" version="1">MPLNGNSSAVAHTCQNASLIALSLFFLPLDFFVLFLSYSVRSFWSTKDGFRGARNVEARKTILVTGIGMTKGLVLARAFSRAGHKVIGADFEPNGALVPGRVSNSLAAFHRLQKPDAGRGSMPYIQGLLDVILREEVDLWVSCSGVASAVEDGEAKEVIENRTDCQAVQFDVATTQTLHEKHTFIDHTSELGLTVPETHTVTSRAAVDEALEQATPGRKFIMKPIGMDDSARGDMTLLPLKTREETSRHLDKLKISDKSAWILQQFVRGSEYCTHAVIIKGKVKVFVACPSAELLMHYEALAPDSALSRAMLKFTEDYAEKGGPGFTGHCSFDFLVEDTSPTDPLRLVLYPIECNPRAHTAVALFNGTPGMVDGYLSLLDDNADGSKTKTSMVVTPAHQDKYYWVGHDLVTRLLQPLMRLLLLQSSVEDFAKAVREVVMHLLLWRDGTFDVRDPLPWFYLYHVYWPMQFLSCIMTGKRWSRINVSTLKMFEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJY5</accession>
    <name>A0A9Q8PJY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Unsaturated rhamnogalacturonyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJY5"/>
    <dbReference type="GeneID" id="71992967"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13089"/>
    <dbReference type="OMA" id="EDGGHNF"/>
    <dbReference type="OrthoDB" id="2305845at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
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    </dbReference>
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        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="379" mass="43318" checksum="87167BAED59556BD" modified="2023-09-13" version="1">MPQQAISVHGLYATDVKQNIELLIDNLVNIKDETGEFLLRLPDGRVFDTKGWNDWEWTHGIGLLGLWQYYAVEGSPKALQVMQDWYKGQLASGTTKNINTMAVFTTLAYLYEKTGEQTYLPWLDSWAEWAMYELPRTEFGGMQHMTYLTDNYNELWDDTLMMTVLPLAKIGLLLNRPHYVEEAKRQVLLHIKYLFDPTTGLFFHGWKFDKAAPGGFGHNFARARWARGNSWLTIFIPDFIELLNLPPGDSFRTHLIDTLEAQCAALRRLQDEEGAWRTILDVPLSEGSYVEASATAGFAYGILKGVRKRYISKDYEPIALKAVNAVLKRIDPSGELKDVSFGTGMGHDLQHYKDIPLTSMPYGQSMAMMLLVELLQRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKG8</accession>
    <name>A0A9Q8PKG8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768400.1">
        <property type="nucleotide sequence ID" value="XM_047912291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKG8"/>
    <dbReference type="GeneID" id="71993021"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13143"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13651" checksum="FB15FD53119FBB8F" modified="2023-09-13" version="1">MSSTALIQFTNSPIDDPQAKFLQKCQTLHNKANALLKLMDALDHTEHRKNLAGAIKHVEYVIESTYVADNGVARGEENLAILHFFMRQDLLEQVKREMREKRGLIEELGLEIFGVEGDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKW2</accession>
    <name>A0A9Q8PKW2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768667.1">
        <property type="nucleotide sequence ID" value="XM_047912770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKW2"/>
    <dbReference type="GeneID" id="71993500"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13622"/>
    <dbReference type="OrthoDB" id="2122304at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371:SF1">
        <property type="entry name" value="BLR7753 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="16333" checksum="5EF886CB8FBBABFB" modified="2023-09-13" version="1">MAATLFDATRNYSLYSIPVMWAISIAPHFYAASLGKFDNKQPRTYTKDTESNQSIDKATKGTIIRAEGAQQNGFENTGLFAAAVVIGNVAKLDNGTLNALAGSYLASRVAYNLCYINGTTEALATGRSVSFLAGIGIVFTLFIKSGNVLYGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMJ6</accession>
    <name>A0A9Q8PMJ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769584.1">
        <property type="nucleotide sequence ID" value="XM_047913403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMJ6"/>
    <dbReference type="GeneID" id="71994133"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14255"/>
    <dbReference type="OrthoDB" id="3904217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="19637" checksum="533EA7270228E244" modified="2023-09-13" version="1">MATNNVWNEHRTRIAGGWKCVSYEMFDNSGPERTLIAKPHGENPLGRVSISRNGWLAAHLARPERMHKLRSGKPWQTAADKEVAYVARGLSMYCGHLKLCQAEEGGLYWPTLVEISTDPNRMGGIEERKVTLLEEDGKSYMVLEPKQDVLLDELTKLEDGTPTRAVLKWEKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR16</accession>
    <name>A0A9Q8UR16_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nonribosomal peptide synthetase dtxS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07436</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763606.1">
        <property type="nucleotide sequence ID" value="XM_047906584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987314"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07436"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000002">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000003">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF3">
        <property type="entry name" value="SIDEROPHORE SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="572"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1668"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1060"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2663" mass="295445" checksum="4BFBB90684747133" modified="2023-09-13" version="1">MRCIPNMASEKDLDQIWTWNETVPVASERCVHDIVSEVCRKQPSAIAVSAWDGDWSYQQLDLYSSRLAHSIQRTGILLEPNDVVALCFEKSKWVPIIALAVMKSGAASILLDCKVPPPFLQKITQKASPVLLISSTKHSQLAERLAAGRPTIQLKSDLIAGLENSDFDHKNLPLVHCRDALYVVSTSGTTGMPKAVVISHTNFSSAIHHQQQMHNFTSRSRIYDFSSYGFDASWSNCLHAFTSGACLCIPSDFERENDLSGSILKYSTTIVDLTPSVARLLSVEAICSLETLIVAGEAVLEADVLRWQAQVKLINVYGPCECTPTATIVALDQTQRFEGAIGPGYGVNCWVVQPDDTDVLVPVGGTGELLLEGPLLGQGYLGEPELTNSSFIKGPSWLSDGHNGCVGRQTRLYKTGDLVRQKADGSLDFIGRKDTQIKLNGIRTELGEIEHHIRHAAPESTGVVVQAAKHQDGDKAILTAFVELDTITIPGLETLLAPAHARLMHPSLVSKLRTELNESLPRHMVPTRFVMFRAFPLTPSGKIDRKRMLEQFKAITKHEFVDPMSRGELSQQHWSDTERSLRNIWSGILGVAKSRISKTDNFFELGGDSLMAMAVIKAAQDVGLYLDITMIFTFPVLENLASESTANTQRTRKSETERPTDNVLDDNRVKEQVASICATRPEIITAVYPCTPLQEGLLALTGQDPEAYINRVALRLGPEVDSELVQRSWNEVVAATPILQTRIVQLPKYGLLQAVIREEIQWHFASNLEDYFQDDKLRYMGLGTPLLHAGLVTVSDSCIYFVYTMHHALYDGWSIGLIYERLTRALRGNSLALPPPFQLFVENTVSATKVAAPAFWAGRMKGFAGEVFPPLPGPNHRAAAKQCLRQTVEDLGWRNQQFTPTTYIRAGWALTVSRYTCEDDVVFGVITNGRSATVEGIREIIGPTIATIPFRVNTYKGTSSIQQLLQCIQDDGTAMIRHEQFGLQRIRRVNKDTEKACQFQTLLVVETSSGLPEEMFEPSLLQTLDGDEVAEEGETQAFDTYGLCLTCTVTGSTVHLSLEFDEAMLDLDQARRMLEQLEHALRQLCDQERKRLHIRDLPVLSDADKKLLVAWNSQVLGTSTICAHDLVTKTACLYPDQTAVSAWDGEWTYSEIDQLSTGLARYLMRCGVVYKSKVALMLEKSKWTPIAQLAVMKAGAASLSLDIGAEQSARTSAILSKVQPTALLTFAANQLPALDLPPSCQHIPLSAAQILNPVQTPDIELPTVGAEDTLYIIFTSGSTGTPKGVVVTHANFTSAIKYQQAAHGFRPLCRVLDFAAYAFDVAWSNLLHTFTVGGCLCIPSETERRERLEECFARYNISHADLTPSVARLLPLSTIATLDTLVLGGEELRPEDAARWAPLTTLINPYGPSECTPTATIACFDQQIETDHQVHIGKGYGVNTWIVNPDDTACLMPIGSVGELLLQGPIVGAGYLNDEELTNKAWIPAPSWLTEICAHPTAAAAGRSRIYRTGDLVRYDPTNGNVLFVGRKDSQAKIHGQRVDLGEIENALSKQPSVEQVVCVLVDQGLLRGKLVAIVTLEDVFDHRQASFQLLDERHYEIARCRLRAMQETARNTLPLHMVPSYWIPLYTFPTNTSGKTDRKALATWIRGLDKASSTKILALMRDHNVRKPVGAREDLLREACGQILNVSSDEIDLEASFMANGGDSITAMQLVSHCRNVNISIKAPDIMKCERLSDLSFAEPSSKSQYHLTVQATSFDTWYELSPIQRWYFELLPPGSVDLAEHHYHQGFQVTLGRSISNESVSAATKHIVKQHEMLRARFQHVQGQWKQKILSPDESKAYEFKICKASSEDDLRKLNRDQHQTLSPINGPVFSVVLVLMPEQKSHILFHAHHLVIDLVSWRIILADLEGLLMGCHSSPPPLSFLAWNQLQIEKSFTSELHPSRVLPPEQHTANYLSFWKFDEASMPNREADHEHLETHLNDKTTAWLFNDANAALNTVPVEIMFSAIWHAFFRTFPERQDLTIFKEAHGRETWRADMDLSRTVGWFTTMSPLSVSRDSTGNVTALVRTVKDRYRQLAAGGWAYWASRHLNPDGIEQFGVHGPVHEVEVNYNGRFQQLEREDGLFQPLDLPLGAETGEKLPAGALFRIEIKVEGGTATFEFGWNRHLAYQDRIRDWAANIASSMAQICSELVEIEKPCLSLCDFPYLGMNYGSLDRLCSNLLPALEHANDAEIEDVLPCSPLVDGILIHQLRSPATYMTSDTYLISPAQSAPKPVSLKRLAEAWQQVIVAQPSLRSVFINSVDISCAFNQVVLKSCNADIIVRSAESRALADRTLASMPELVSNGCTPPHRLTLCRVKDSPDVLCRIDMSHAITDGGSSGILLDHWSSTYNRLDDPKHDIAKTCPNFASHLIRVRDSEAKTSYWQDKLQGLQPCLFPQLESLQPHDVQRYNTEFEADHASAVHDFCTRHGTTAAGLFQTAWACVLSSYTKSHDVCFGYLASGRDLDIPGLQDAVGAYTNMLVCRVDTSGARDAVFVRSVHQQMLKDLDFQHVSLAEVQHLTSAGPGRPLFNSIVSFQHAANVSQIVDHRSADFEAPVEHGALAFKLLTVKDPSEFDLCVGISYSRTHVGVCLEYRSDCISEDAARKVIVDLEDTVVAIMGAVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR37</accession>
    <name>A0A9Q8UR37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763682.1">
        <property type="nucleotide sequence ID" value="XM_047905876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR37"/>
    <dbReference type="GeneID" id="71986606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06728"/>
    <dbReference type="OMA" id="VMQFFAR"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF67">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_5G09340)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="25561" checksum="22646D26E995EF0A" modified="2023-09-13" version="1">MGRLPRTDDFPSSIKLNIVPPPGTDPPTNILLLLHGLGDTHDSFTTLAKQMSLPETVGISVQGPSALLDLGGKHWGDDIIFDSTTGGLDPDAGFKQSTKLLRDVVEDVLVGKCGYATREILMFGFGQGGMAALELGATFHTTPLSGIISIGSGLPTTSPASPDPKSKTPILVCGGSDQSAVTSTTEDKLKRVFEHVEVKRYRKPGDAMPANRDEMMPIMEFFSRRLRSGKGVPEGAVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URJ9</accession>
    <name>A0A9Q8URJ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pheromone-regulated membrane protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09987</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764189.1">
        <property type="nucleotide sequence ID" value="XM_047909135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URJ9"/>
    <dbReference type="GeneID" id="71989865"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09987"/>
    <dbReference type="OMA" id="QHFIFVP"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="666"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="746"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="8">
        <location>
            <begin position="352"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/Serine exporter ThrE" evidence="9">
        <location>
            <begin position="619"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="85160" checksum="ABD902E088DC9D4C" modified="2023-09-13" version="1">MDGPSQSSNPGEQDDDPDVKKPNEPEAKQRRARVRVTSRATEVPPLPHSPPRTRPQHRTSLSPRPPSILRGPSREPSPSGRPEDDPNCPRDRAAAAAQSRGHALANTVWRDTPSISARSSFESISSSSSSGDSDYNLLGNQQDIALQPLGEQTQASDEQYGTAQTAISFQDGASVEVEAQKPTAEAGEALGTSDSTDTTKPEEKPKTDSNEIYNTSVDGLYHVPAPERYRGGVLGQMLKLYKQPDFQSIREGLASSSKHASPKHRRSPSDVETVSTTPERRKWYDQNASQDTLATLIGASTNLAKPAQPQDGIKKPRHHKRDHSLASRFSQFFNQEEAHVKQHIAGIVARREFILKCCRALMLYGAPTHRLEEYLTMTARALQIEAQFLYIPGCMIISFDDAETHTTEVKLVRLTQGIDLGRLKDVHRIYKEVIHDVIGVEDATAQLEDLMVKKAKFHPWLRVLVFGLTSVTAAPFSFDARLIDLPLSFCFGCVVGALQLIVAPMSPLYSNVFEVSATVLISFLARAFGSIRGGDLFCFSALAQAGIVMLLPGYMFLSSSLELQAKSIVAGSIRIVYGVIYSLLLGFGITLGAALYGMIDNNATSELTCKAPMPGTYGFIFVPFFVLCISMLYQAKWRQMPVMVLVAFAGYVVNSYSSKRFNSSPQIASTLGAFAVGALANLYSRFRHGVAAAILIPAIFTQVPGGLASTGGLLSGLQVANEINNVTSAVNTTTADPMGLGTGSSYIVFGVASSMIQIAIGITVGLFLSALVVYPLGKRRSGLFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT10</accession>
    <name>A0A9Q8UT10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765737.1">
        <property type="nucleotide sequence ID" value="XM_047910447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT10"/>
    <dbReference type="GeneID" id="71991177"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11299"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="40740" checksum="4B5A2C620F5133E4" modified="2023-09-13" version="1">MDESPVNGADRSSTSKPSGRKNCDQDATNVSPEEVPPKKLGNRISRLLKRRSGTATTKSEEEKATNETNQKRRQQVYQAQKRHRNRQAEYVANLETEVAQLQHLDSVAHAEMNALAHENMLMQQLLASKSIDHQLECLSLAPTPIPAEDMSQLGSAAVEVRYDPVVGHERTFVDVADRMRFGNGDDACNSGQSTKQGVVDGDNWAALDFILCLEHCCQDHTPHGGINPTAYHCERDGSHGHALSMSSAVYESALPTSDRADLEDAQLYGGLRSPPQSGREKWQLPHSEIDKLVALSQQIPIDDSEMTPAQAYKAIQESVPDAAYVKPVMEALKVLLAPHVACFGFGAVMPAAAFWDHLDTVLKALGLEAENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT71</accession>
    <name>A0A9Q8UT71_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765873.1">
        <property type="nucleotide sequence ID" value="XM_047908417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT71"/>
    <dbReference type="GeneID" id="71989147"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09269"/>
    <dbReference type="OrthoDB" id="3913028at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="20162" checksum="02ED5CA8ED955954" modified="2023-09-13" version="1">MSATKTEPGANKVDTGLTDSTHGSASSSASAERYRLDEFDETPILLYKYRGGLQTSSQKDLCSWLDKDEKLRVTKKQIPRMSSYVEIKRHDLYLPDEQEMYKTLPNYDSSLASIKLPSTAYWSRLFLGNYDNLYIVSPETTPTSSVADEDSQRTSPTSTWGQGSEELARMGATEEHRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTU9</accession>
    <name>A0A9Q8UTU9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-binding monooxygenase moxY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766622.1">
        <property type="nucleotide sequence ID" value="XM_047908162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTU9"/>
    <dbReference type="GeneID" id="71988892"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09014"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF6">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15050)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="605" mass="68330" checksum="F833A01E1913AE93" modified="2023-09-13" version="1">MGSIDEDVHLKGNNHTSLKTSTIIEVVDDVSQPPIDDTKTYQPRWVYPHPTEFKVSEHPIDEVKTLKVAVIGGGLAGITAGILLREKVPGIDLTVLEKNADFGGTWYENRYPGVRCDIPAHVYQSTFSPNTQWSEEYAQGHEILVYWQSVAKKYDLYKNTRFQSKVLGAHWDDHRAQWRIEIEDLGANTRSAEHYDFVLTAIGHFNEWKLPDYPGINEYQGHLRHSSNWDPAFDPVGKRIATIGNGASGIQVTAELQKLASHVDHYARNRTWIAGSFNPAAQDRQQTPIAIPDEQREAFKDPQTYLKFRKELENNFFRGFDGQLIESQASKEATQNFIELMRKRLTGKPELLNDLVPDFPPHCRRLTPGPGYLEALTADNLSLIQTPIERFTADGIVTVDGVHRPVDAVICSTGANVNYAPPFPITSGDLDLSRDWRPDGKFGWPYSYLGISTPGPNPAGPSGTVPHAVETQVTYVAKMLRKMSSQRIRTITPLKSATDDFVAYADAFFPRMNVSLNCSSWSNGGRPGARIHGHWPGSGAHINHVRREPRWEDFQYTYDRPENMFAYFGNGQTAKEQDPNSDMTPYLKLAGENDLRDLHERWWDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUF8</accession>
    <name>A0A9Q8UUF8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767206.1">
        <property type="nucleotide sequence ID" value="XM_047911499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUF8"/>
    <dbReference type="GeneID" id="71992229"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12351"/>
    <dbReference type="OMA" id="WGQDIFP"/>
    <dbReference type="OrthoDB" id="5341873at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018803">
        <property type="entry name" value="Ish1/Msc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10281">
        <property type="entry name" value="Ish1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="87" mass="9747" checksum="0AA60F629408E736" modified="2023-09-13" version="1">MPTPLDRALNSKNLFLGFTGLVAAATAWSIWGGDMFPKEEDPKGEPEAWTETEMKRWLNARNLMAGSTATREELLARVRANMRAPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW07</accession>
    <name>A0A9Q8UW07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768884.1">
        <property type="nucleotide sequence ID" value="XM_047912739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW07"/>
    <dbReference type="GeneID" id="71993469"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13591"/>
    <dbReference type="OrthoDB" id="3553147at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="32"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="507" mass="57122" checksum="CAD7DDC3D9DACA4A" modified="2023-09-13" version="1">MQIRILTLHPANRSQPLSGSLQVVNLRGGLGYVALSYAWGAVDKPCTLQVDGQALPIGRNLHAALVQWRDLLEPTYLWVDSICIDQSNSDELTEQIAVMGRIYSSAVSTLAWLGNGYDDQTNCQLFDFLLFLSNHNASMLMMGPPTEPPLDEFYRSYKSARTADSKSPIKVTLMQDLLHFCKNPYFTRRWVVQELGAAHHVRVQLGSAHIDGSLLANASILLNKERSPIRDIEGFNGIMLVLQRNNENVLERLERFRQFECRDDRDRVAALLWAPCRLPSDSSGSREFRIEYARSVDDNYTKFALDFLQYSRDRPSNGRYMLCAAARRHCNGSRRHGTLPSWVPDWRAEPILNIVELAPLLDNSPATVHREHSLTVTYLRPSFSSRPESMTALDIKGRAKALHLSINSATHSTMMVVADPNGVLQARDCVVDLRLGIWSPSRINFESWAVHPIVLRRKNGNHHGHAIWEVVAGLYLEASPFPGNDSGKGVEVWYAHAKSEPVVLYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWQ1</accession>
    <name>A0A9Q8UWQ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Sulfate adenylate transferase</fullName>
            <shortName evidence="9">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET3</name>
        <name evidence="13" type="ORF">CLAFUR5_14407</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="9"/>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWQ1"/>
    <dbReference type="OrthoDB" id="468at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010134">
        <property type="term" value="P:sulfate assimilation via adenylyl sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000003">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000802">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000052">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="12">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="11">
        <location>
            <begin position="174"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="10">
        <location>
            <begin position="395"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="9">
        <location>
            <begin position="395"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="291"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="434"/>
            <end position="437"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="9">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO25225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="575" mass="64606" checksum="09F6FC3E4B0F1D26" modified="2023-09-13" version="1">MANPPHGGVLKDLIARDAPRRQQLSEEAERLPAVVLNDRQLCDLELILNGGFSPLEGFMSEKDYNGVVENNRLADGNLFSMPITLDLNQAEIEQLGIKAGARITLRDSRDDRNLGILNVEDVYKPNKDKEAKEVFGGDPDHPAVKYLFKQTGEYYVGGKIDAIDRLMHYDYVGLRYTPAELRLHFDKLGWSKVVAFQTRNPMHRAHRELTVRAARQRQANVLIHPVVGMTKPGDIDHFTRVRVYQALLPRYPNGMAVLGLLPLAMRMGGPREAVWHAIIRKNHGATHFIVGRDHAGPGKNSKGEEIYGPYDAQYMVEKYRDELGIEVVPFQQMTYLPDTDEYRPKDEVPKEVKTLDISGTELRRRLRTGGDIPEWFSYPEVVKVLRESHPPRNKQGFTVFLTGYTNSGKDAIARALNVTLNQQGGRSVSLLLGETVRSELSSELGFNREDRDKNIQRIGFVASELTRSGAAVIAAPIAPFTESRKAAREIVEKHGSFYLIHVATPLEYAEKTDKRGIYAKARRGEIKGFTGVDDPYEAPKDKEADLVVDISKINVRTAVHQIVLLLEAEGLLDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-04-03" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>L7YE01</accession>
    <name>L7YE01_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6 9 23">Avr4</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="16">Avirulence factor AVR4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">avr4</name>
        <name evidence="23" type="ORF">CLAFUR5_10112</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2012-11" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">ALH</strain>
            <strain evidence="7">CH6</strain>
            <strain evidence="4">COA</strain>
            <strain evidence="8">ELH</strain>
            <strain evidence="5">EMP</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2014-09" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="De Wit P."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CHEAV</strain>
            <strain evidence="11">COL</strain>
            <strain evidence="10">COM</strain>
            <strain evidence="13">EAV</strain>
            <strain evidence="12">ELS</strain>
            <strain evidence="14">EOP</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>Development of a real-time PCR assay for the identification of races of Passalora fulva.</title>
            <authorList>
                <person name="Li S."/>
                <person name="Xu X.Y."/>
                <person name="Li J.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race 2.5</strain>
        </source>
    </reference>
    <reference evidence="17" key="4">
        <citation type="submission" date="2018-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Medina R."/>
                <person name="Lucentini C.G."/>
                <person name="Ernesto M.E."/>
                <person name="Saparrat M.C."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CIDEFI323</strain>
            <strain evidence="18">CIDEFI325</strain>
            <strain evidence="20">CIDEFI327</strain>
            <strain evidence="21">CIDEFI329</strain>
            <strain evidence="22">CIDEFI330</strain>
            <strain evidence="17">CIDEFI332</strain>
        </source>
    </reference>
    <reference evidence="16" key="5">
        <citation type="submission" date="2018-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Medina R."/>
                <person name="Lucentini C.G."/>
                <person name="Franco M.E."/>
                <person name="Saparrat M.C."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CIDEFI322</strain>
        </source>
    </reference>
    <reference evidence="23" key="6">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="23" key="7">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KC132827">
        <property type="protein sequence ID" value="AGD98909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132828">
        <property type="protein sequence ID" value="AGD98910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132829">
        <property type="protein sequence ID" value="AGD98911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132830">
        <property type="protein sequence ID" value="AGD98912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132831">
        <property type="protein sequence ID" value="AGD98913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609221">
        <property type="protein sequence ID" value="AIZ11405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609222">
        <property type="protein sequence ID" value="AIZ11406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609223">
        <property type="protein sequence ID" value="AIZ11407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609224">
        <property type="protein sequence ID" value="AIZ11408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609225">
        <property type="protein sequence ID" value="AIZ11409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM609226">
        <property type="protein sequence ID" value="AIZ11410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM880021">
        <property type="protein sequence ID" value="AJF35003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK313783">
        <property type="protein sequence ID" value="QDH45899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK313784">
        <property type="protein sequence ID" value="QDH45900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK313785">
        <property type="protein sequence ID" value="QDH45901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK313786">
        <property type="protein sequence ID" value="QDH45902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QDH45903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK313788">
        <property type="protein sequence ID" value="QDH45904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QDH45906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="L7YE01"/>
    <dbReference type="SMR" id="L7YE01"/>
    <dbReference type="KEGG" id="ag:CAA55403"/>
    <dbReference type="OMA" id="DCLYPNP"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007688101" evidence="2">
        <location>
            <begin position="19"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AGD98909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AGD98910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AGD98911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AGD98912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AGD98913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AIZ11405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AIZ11406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AIZ11407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AIZ11408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AIZ11409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AIZ11410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AJF35003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDH45899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDH45900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QDH45901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QDH45902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QDH45903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QDH45904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="QDH45905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="UJO19575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="14559" checksum="CE2A2C29B7F2A7E0" modified="2013-04-03" version="1">MHYTTLLLSTLLVGTALAQPTNPPAKTPKKAPKTQPYNPCKPQEVIDTKCMGPKDCLYPNPDSCTTYIQCVPLDEVGNAKPVVKPCPKGLQWNDNVGKKWCDYPNLSTCPVKTPQPKPKKGGVGGKKASVGHPGY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-12-05" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>P0CU67</accession>
    <accession>A0A9Q8PJB6</accession>
    <name>CLAG_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Atrochrysone carboxylic acid synthase</fullName>
            <shortName evidence="1">ACAS</shortName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cladofulvin biosynthesis cluster protein G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Non-reducing polyketide synthase claG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">claG</name>
        <name evidence="11" type="synonym">pks6</name>
        <name type="ORF">Clafu184395</name>
    </gene>
    <organism>
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2014" name="Mol. Microbiol." volume="92" first="10" last="27">
            <title>Functional analysis of the conserved transcriptional regulator CfWor1 in Cladosporium fulvum reveals diverse roles in the virulence of plant pathogenic fungi.</title>
            <authorList>
                <person name="Okmen B."/>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="van der Burgt A."/>
                <person name="Cox R."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24521437"/>
            <dbReference type="DOI" id="10.1111/mmi.12535"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2016" name="Proc. Natl. Acad. Sci. U.S.A." volume="113" first="6851" last="6856">
            <title>Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Saccomanno B."/>
                <person name="Vaisberg A."/>
                <person name="De Wit P.J."/>
                <person name="Cox R."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27274078"/>
            <dbReference type="DOI" id="10.1073/pnas.1603528113"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2014" name="PLoS ONE" volume="9" first="E85877" last="E85877">
            <title>Secondary metabolism and biotrophic lifestyle in the tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="Iida Y."/>
                <person name="Karimi Jashni M."/>
                <person name="Battaglia E."/>
                <person name="Cox R.J."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24465762"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0085877"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>FUNCTION</scope>
        <scope>DOMAIN</scope>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2018" name="Mol. Plant Pathol." volume="19" first="369" last="380">
            <title>Down-regulation of cladofulvin biosynthesis is required for biotrophic growth of Cladosporium fulvum on tomato.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Overdijk E.J.R."/>
                <person name="Saccomanno B."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27997759"/>
            <dbReference type="DOI" id="10.1111/mpp.12527"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="7 9 10">Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:24465762, PubMed:27274078, PubMed:27997759). The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG. The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078). This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078). The cytochrome P450 monooxygenase claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>holo-[ACP] + 8 malonyl-CoA + 8 H(+) = (3R)-atrochrysone 2-carbonyl-[ACP] + 8 CO2 + 8 CoA + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:64232"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:20479"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:234110"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:64233"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Pigment biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="7 8 9 10">Expression is positively regulated by the transcriptional regulator wor1 (PubMed:24521437, PubMed:27274078). Exhibits high expression at the early stages of infection when runner hyphae were growing on the tomato leaf surface (PubMed:24465762). Expression drops after penetration when the fungus is colonizing the apoplastic space between mesophyll cells (PubMed:24465762, PubMed:27997759). The expression is induced at later stages of infection when conidiophores emerge from the plant and produce conidia (PubMed:24465762).</text>
    </comment>
    <comment type="domain">
        <text evidence="13">Multidomain protein; including a starter unit:ACP transacylase (SAT) that selects the starter unit; a ketosynthase (KS) that catalyzes repeated decarboxylative condensation to elongate the polyketide backbone; a malonyl-CoA:ACP transacylase (MAT) that selects and transfers the extender unit malonyl-CoA; a product template (PT) domain that controls the immediate cyclization regioselectivity of the reactive polyketide backbone; and an acyl-carrier protein (ACP) that serves as the tether of the growing and completed polyketide via its phosphopantetheinyl arm.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="9 10">Impairs the production of cladofulvin (PubMed:27274078). Does not affect virulence (PubMed:27997759).</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767848.1">
        <property type="nucleotide sequence ID" value="XM_047912053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CU67"/>
    <dbReference type="SMR" id="P0CU67"/>
    <dbReference type="GeneID" id="71992783"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12905"/>
    <dbReference type="OMA" id="CKTWDAT"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0596">Phosphopantetheine</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000445887" description="Atrochrysone carboxylic acid synthase">
        <location>
            <begin position="1"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="4 13">
        <location>
            <begin position="399"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="3 13">
        <location>
            <begin position="1730"/>
            <end position="1804"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal acylcarrier protein transacylase domain (SAT)" evidence="2 13">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Malonyl-CoA:ACP transacylase (MAT) domain" evidence="2 13">
        <location>
            <begin position="949"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Product template (PT) domain" evidence="2 13">
        <location>
            <begin position="1372"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1502"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1644"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1654"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="4">
        <location>
            <position position="572"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="4">
        <location>
            <position position="723"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="4">
        <location>
            <position position="766"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1560"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1764"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q5BH30"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="8">
        <source>
            <dbReference type="PubMed" id="24521437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="9">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="10">
        <source>
            <dbReference type="PubMed" id="27997759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="11">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="12">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="13">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <sequence length="1805" mass="197105" checksum="115BAAB3F5C327D3" modified="2026-01-28" version="2">MTTNHLENKVHAATESLFYFSNEFPKRDLQDLFRQAHTRSKLAQHKCLAQFIQDATQTVKQEIQGLSMKLQHLFKPLESVLTWAEDHELREGALSGAIDGVLLIVAQMTTLIGYLENNTAKMDDIATASLAGLGVGLLTACAVSSASTIADLSATGADAVRTAFRLGVHVYYVSQTLEALDPSARPETWAYVINNVTPTEAQEQLDTLYANSTQPATSKVFISALSRSSVTVSGPPARLKALVTGSEFFRTSRYIALPVYGGLCHAPHVYGQDDVDMVMQSRAFSVQKAPATHLKSVWSTSSGYPYLVEDSKSLFASVVAELLTKAICWDSVVSSIVKYTGLTDASEMIIYNYGNSIPLNELESALKSSPAKLKVVNSNLLSWMGHNSPTSVKPRNTLQSKLAIVGMSCRLPGGATSNELFWDVLRRGVDTSQVIPADRFDVATHYDPAGKQLNKSMTQYGCFIDEPGLFDAPFFNMSPREAQTVDPQMRLALVTAYEALEQAGYVANRTASTRLERIGTYYGQAADDYREVNQGQEVSTYYIPGGCRAFGPGRINYFFKFAGPSYSIDTACSSGLAAVEVSQVTSIVAPTNHGQVACQALWRGDVDTAVTGGVNILTNPDGFTGLCSGHFLSKGHNACKTWDATADGYCRADGVGSLVIKRLEDAEDDNDNILGVILGAGTNHSAQAVSITHPHAGHQAYLARQVLRQAGVDPLDVSYVELHGTGTQAGDSEEMQGILDVYAPLSKRRSQSQPLHIGAVKANMGHSESSAGTTALVKVLLMLQNNVIPPHIGITTEMNPKFGHDFKKRNLHIPFELTPWEHTDDKRRIAVVNNFGAAGGNTTMILEDAPMRSISQSDTRKTHVVVLSAKTKTSLVANVDRLISYIDSHPDTQIANVSYTTTARRYQHVLRVAISTSEIAHLQKQLYSHREKIEYIQPVRKAEPPPVAFSFTGQGASHKSMNLELYRDVPTFREFVHQLDSLTRAQGFESFICALDGSHDKDHQHSPVVTQLALVCSEIALAKYWASIGVLPNIVIGHSLGEYAAMHIAGVISASDAIFLVGRRAQLLQERCKIGSHLMMAVRASVDQITQSAAGKPFTVACVNGPADTVLAGTKEEIEVIKTPLESSGLQCIKLDVAFAFHSEQTDPLLDDFEALAKSGVIFAEPKLPVISPLLGKVIFDAKTINATYVRRATREAVDFLAALNNAQEIGAIGGDTVWVEIGPHPVCTGFVRSTIPSVKLALPSFRRGEENWKTLSDSIAQLYTVGVDIDWTELHRPFEKNLRLLDLPTYAFNEKTYWLQYKGDWCLTKGNTFYADEQKIVRGQLPSVSELHTSTVQQIVEQVFDTDTGSCTVVIESDMMQPDFLAAAHGHRMNDCGVATSSIHGDIAFTLAEHIHKKLGVHGKDTRYNVANLQVTKALVARKNTANPQVIRVTASTTDVRSGIDLVWQNINANGDSAEPFATSSIHAGISTDWISSWSSLTHLVRDRIETLDRLVAEGKANRLSHNMAYTLFASNLVDYADKYRGMQSVVMHGLEGCADVELSTKESGVWTVPPYFIDSVAHLAGFIMNCSDAIDAKKFFCITPGWKTMRFARPLVPGARYQSYVKMIPTVEDDTAYFGDVYILQDGVIIGLVEGIEFHRYRRILLERLFSAPDSTNLDDTTETKDISSSTQHSVPVSRQVPPAAKSSAQTVFESSLPFAVPGPRKSTARPAVDEIAAREKPVASQSSSITNRAMQLIADEVGVELADLCDDVGFSDLGVDSLMSLVIADTFRATLDIKVNGSLFLDYETIGDLRNWLEETYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXM5</accession>
    <name>A0A1P8YXM5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp28-3</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 28-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp28-3</name>
        <name evidence="3" type="ORF">CLAFUR5_02977</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <source>
            <dbReference type="EMBL" id="UJO14632.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
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                <person name="Stergiopoulos I."/>
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            </authorList>
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            <begin position="1"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11335.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <text evidence="1 6">Belongs to the universal ribosomal protein uL3 family.</text>
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    </dbReference>
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    </evidence>
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    <sequence length="392" mass="44480" checksum="29F8EC2967E2B63D" modified="2023-09-13" version="1">MSHRKFEAPRHGSLAFLPRKRASRHRGKVKSFPKDDQKQKPHLTAAMGYKAGMTTIVRDLDRPGAKLHKKEIVEAVTVIETPPMVVVGLVGYIETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYAKKHAEEGGKNITRDLERIKKYCTVVRVLAHTQIHKTPLKQKKAHLMEIQVNGGSIADKVEFGHGLFEKPVEIDSVFEQDEMIDCIAVTKGHGFQGVTSRWGTKKLPRKTHKGLRKVACIGAWHPSHVQWTVARAGQMGYHHRTSVNHKVYRVGKGTDERNATTDFDHSNKQITPMGGFVRYGEVKNDFVLLKGSVPGVKKRVMTLRKSMFIHTSRRALEKVELKWIDTSSKFGHGAYQTAAEKKQFVGTLKKDLVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7W8</accession>
    <name>A0A9Q8L7W8_PASFU</name>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7W8"/>
    <dbReference type="GeneID" id="71980675"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF0">
        <property type="entry name" value="DELTA(24)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="498" mass="56905" checksum="0410F625480410AA" modified="2023-09-13" version="1">MEEHKRAVSRIASQVVDFHQRQVPYRIYHGSTNTTQVREFDSKKIIDTSGLNHVIGVDTEKMTCLVEPNVGMEGLVDGTLPHGVIPPVIMEFPGITVGGGFAGTAGESSGFKYGFFDRIVNWFEIVLPDGEVVRASPTEREDLFHGAAGSFGTLGVATLFELQLIPAKEYVEMTYQPCRSVKEAISTMDVVTNDGTNDFVDGIQFSLTKGVIVTGKLTDQPSSGSKIQHFSRAQDPWFYIHVDRATRGFEKVTVVAPVKDYLFRYDRGAFWTGKYAYRYFLTPFNRVTRWALDYFMHTKVMYHALHRSGHSSRYIIQDLLLPRSGVEEFVQFVDDQYGFWPLWLCPLKRGEHVSLHPTIGGDPPTDEKSVSFINIGVWGPGSSNYVKFIEQNRQLERKLRELGGIKWLYAQAFYTEDEFWSIYDRKWYEALREKYHATYLPSVFEKVRVDLSKTHASTDKRSTWLRTQLWRVWPVSALYGVAKTLLEREYGLAKGKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L843</accession>
    <name>A0A9Q8L843_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01209</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO12537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900357.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981087"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01209"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATP dependent RNA helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="138"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="580" mass="64795" checksum="FDBD9A9ABF978A06" modified="2023-09-13" version="1">MRCQIGQEVGYSIRFEDVTSASTRIKFLTDGLLLREALVDPLLSRYSVIMVDEAHERSLSSDILLGILTKIRKKRPELRTVISSATLQAQQFLNFFGDSGEAVHPKDDESQPPGRIISVEGRAFPVDLHYLLEPCEDYLERAVKTVFDVHSSGPEGDILVFLTGREEIETMIEMIADRLPSLAADTDKILPYPLFAGLSTEQQMYVFEPAPENTRKVICATNIAEASVTIDGIAYVIDSGFVKLRAYNPTTGIETLTATPVSKASATQRAGRAGRTKPGKCYRLYTEAAFTSLPDATVPEIQRSNLAPTILQLKAMGIDNIARFNFITPPPAELIMRALELLYSLGALDDYAKLSKPIGFQMAELSLEPMLAKCLLSAPAFKCLSEMLTIAAMVSLQGNVWFSHDTKKAEETARRKFAVEEGDHLTLLNAYQAFITKGKKDSKWCQQHYLNFKSMTRAVSIRNQLRRYLERLGIDVNESLGGNDVLRAGGRPKEESIRRCLTSGFFAHAARMMPDGTFRTVDGGTVLHAHPSSLMFNRKADWVIFTEIMETGDKTYIRDVTKIEKSWLLQYAPDFYRVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L893</accession>
    <name>A0A9Q8L893_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00504</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756991.1">
        <property type="nucleotide sequence ID" value="XM_047899652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L893"/>
    <dbReference type="GeneID" id="71980382"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00504"/>
    <dbReference type="OMA" id="WHAKAPL"/>
    <dbReference type="OrthoDB" id="5362656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="451"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="537"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="639"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="788"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="828"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="878"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="639"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="797"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="918" mass="99195" checksum="36D5185182F16601" modified="2023-09-13" version="1">MPATRQVSKNSPTPRNTSAQQDFVFPENSHLLITTPRHVFAWDRSGIRPIFRSKAGGIVAAREAKDGSGVLAVASSNVVVMHDARRRKDESWGLNAPREEVRHLEYSPDATSLFLSTTSGGAIQHYSTEKQRLLDPAQTHHAAPVALAISPTGHLMLSASQDPPMVFLKNLAHNTSPLKIQPQASDAAVCCAVFHPERPNVFLLAFRDGTVAAYDATKMPRNNRGTYANQQSVNDGEIAHLQKVHRATAADADAAPIAGITFLPGYKTRAITAGRDGRCKLIDFTKGGETLRTWHAKAPLTSIAVWGLRAKAEPGSLREVASEHRRNRSSSSHTIGGPTSTSSIIAVSRLDGKVQLYDSVGLLLAQRAVSSLEEQILSLEWAKGAAPESHVTDALGRHFSDAESIPPIPITKQRVVSSPPTIAAQKEAHKEIVPARTGLGLPAELRTRPPSRQFTIHPDEEAQGTVQYTPSPKRQPTGSAQVVNYQDLFSPVKVSNPAEQSPAKRLVSNSPRTRPCISSQTFVKSPAVLLSSSAAVSPGQATSKSPSTHFTSAASECVPHKSDKVSSLKPKHRVSSQASPLSRAKRRITFQQSGDGSTRSINSGSPKLINSNAKVLADLRRLNKDDLTNQRYGTLSSYAAVQRTGSANDSQRSKASSIRPPPRARSNKPRSPPSIHVHDPSTWPSDSNADSHSTDIWFTSGSEDDTSHKRRRRMKPLTRPPARQTSRSRITSKGTISTGLPTDPSQALPAHDGWTDGDGDRYLTAQSRLSPVASLSLISEDLRNLFPRTSSLSPNKQTRTARTGQTRAPVGKDGTLTERAVNAVATGRPPCSPWDKVKASKSMQPSPSRKHDAVKFYEGPCTMSGALPQRELVVCSTCPETNSRLKDLEGQVAQLRGEVLAMKAVLRRDGVPLPACLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8H9</accession>
    <name>A0A9Q8L8H9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7905 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757168.1">
        <property type="nucleotide sequence ID" value="XM_047900780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8H9"/>
    <dbReference type="GeneID" id="71981510"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01632"/>
    <dbReference type="OMA" id="WDNMLGQ"/>
    <dbReference type="OrthoDB" id="4739136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057227">
        <property type="entry name" value="DUF7905"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25482">
        <property type="entry name" value="DUF7905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7905" evidence="2">
        <location>
            <begin position="397"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="748" mass="85004" checksum="CB5F3DCDCE65EE04" modified="2023-09-13" version="1">MDDYELENAREWDDSLADKPRFEWKTVGGRGKPPSKATPAPAPAPAPAPAPAPPPKTPTPSRNNRYTPAKRSLQASPAQHQNYRPSQGPSRLPPPRFSPQNRAPRQTHPDRPRPQAPGRPVPRLVENADNEAQYAWRERRPPTDTVRIPAVMVHADRDMNDPATYVQLAVDCGAFVYCEELKSDNVSLTFGIWGDAKAASAAKRQILNWIEYAEPSSHRAPGAAKWARIVSLTPKLRERAEKRWATDIKKNRYRQFPPTNKAFGAIGTFHWPSKEFRPEEAFGMSCEAFDPIRMEHSCYIIYSSEKSIFQVFGKVQDVQAALLCIRKTAFNICSRTINPVRAYMLQWRSGPPPSHVFLEEYMGPVIIASQGKEAIGQDPSYSPRGEGVLDDESAVQLAHTRASVNAERVKTTIRNALRKVHYLQGHLNFRIRLGTFLLAQYKKLSDGELWELADYEEMVGASQFVGRVTEELGGEYPEHTVLSKLQHATDLLSPQDAITEHLVDVRPSYAAEFIFANTKGDLCLKVTWIESSDDNSDELEFLESTKEWTRLDRDTSHATKLVDMSLTDLQTGSAWQFEMLSSEPMEHAKLPQELRHFADKVRIDVVALRKKSSEKSFIVFNPFVQPKLVRQTIRYQYGIIGTDYTLELSQFQDRTYPAKKSVADNPVPTVYEPRWGLNVFRIEWDTMFTENARLTIGASVDWADDMENWFPQDWVLNADDDGKQDGFAQLMRKLMKVEKLVREPMLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9T1</accession>
    <name>A0A9Q8L9T1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03096</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757916.1">
        <property type="nucleotide sequence ID" value="XM_047902244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9T1"/>
    <dbReference type="GeneID" id="71982974"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03096"/>
    <dbReference type="OMA" id="QIFPIVQ"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF1">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040243253" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="18"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="17"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="21155" checksum="2710D133395905D4" modified="2023-09-13" version="1">MLRSLLLTLAAAGLGAAHFTLNWPETAGFSDDDEPTAPCGGATVVVNDTAPEINVDRFAVAIFSSHPAGNWTFRATQSTEEPYDFTDIVPGVSSTGPGDFCLTHLRAPSDWAGSSGILQVIDNSVDGTLYQCAPVRFVSGANDTAGASCRNNTGFSATFSSAETSNSSGTSEETPSGTAAPSASSSAAAAAMATGVGSVLGLGLLAAGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA13</accession>
    <name>A0A9Q8LA13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757892.1">
        <property type="nucleotide sequence ID" value="XM_047902870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA13"/>
    <dbReference type="GeneID" id="71983600"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03722"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="59" mass="6740" checksum="ED23FC598C2AFF88" modified="2023-09-13" version="1">MLMTEIYQKAFHASSVFASISRPLKRHCERVLVQKQARKASYAFGAMCWVLKTTFNNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA58</accession>
    <name>A0A9Q8LA58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758038.1">
        <property type="nucleotide sequence ID" value="XM_047902482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA58"/>
    <dbReference type="GeneID" id="71983212"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03334"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="14071" checksum="C337043ED9B0E84B" modified="2023-09-13" version="1">MLVHNKVQGQNSNHSLFKSVGRAAKEDLHKTLSQWGKKCKDIIEKGHGKIKNDFQSRYQEADVKQEDDPKAVSKLLDAVKKAGTILDGDMRRHLFECHKYENDVEAMKEWKQAEMRQRHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA92</accession>
    <name>A0A9Q8LA92_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757409.1">
        <property type="nucleotide sequence ID" value="XM_047899579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA92"/>
    <dbReference type="GeneID" id="71980309"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00431"/>
    <dbReference type="OMA" id="LTEVFAC"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000005">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO13043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="46691" checksum="A24D9813116BCA1B" modified="2023-09-13" version="1">MASSSLRTLLPRSTRGLASAGQKSARCAVGQAQKRQYSTPLRAPDASDPRLSAIDVSQLSITKTASPKPITPNEELVFGRAFTDHMMSLEWTATDGWLPPRITPYQNLSLDPATCVLHYAFEAFEGMKAYKDKEGNVRLFRPDKNMARMNKSVSRIALPTFDGEAVIDLIKRFAKMEERFIPSKRGFSLYLRPNMIGTQRTLGVGPPGSAMLYVIASPVGPYYPTGFKAVSLEATDYAVRAWPGGVGASKLGANYAPCIVPQMQAASRGFHQNLWLFKELDPATGIEEDYVTEVGTMNLFAAIVNTEGQKELMTAPLDGTILEGVVRDSVLALARERLAPQGWKVSERRFAMRELVDAANEGRMIEVFGSGTAATVSPVRAISYKGKLVDCGIPEGEEVGPVCLQMKDWIEGIQYGEEEHPWSVKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAE6</accession>
    <name>A0A9Q8LAE6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758232.1">
        <property type="nucleotide sequence ID" value="XM_047901493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAE6"/>
    <dbReference type="GeneID" id="71982223"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02345"/>
    <dbReference type="OMA" id="SINGWTR"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF84">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="35040" checksum="2E0EF134D90CE089" modified="2023-09-13" version="1">MPDFASLEYWDNRFEKDSKPFDWLVPATALRDVTQDMIEAEALQEAEILHIGAGTSDCFVLRELVSNPGQIHNVDYADPAVAIGQTRERELLTKEDDKEQNRDLLDIIDNKHDSVQQTELPKSMRWSCMDLLDLRTTLDLHRSQLQAGKLYDLVLDKSTSDSIGCGADLHLILPYALSINGWTRRLQGSGTTQPAHVHPLHILAVHLAALTTPRTGRWLAISYSEDRFPFLPPFPPTAGNGLLSDDAIKAGFPHPHQLWRLETKSRIELEEKEETLAERKKRLSLGYVHRPQVSHWLYVLKRTDALVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAG8</accession>
    <name>A0A9Q8LAG8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Abnormal eversion of vulva protein 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_02943</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO13766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902091.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_02943"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000981">
        <property type="entry name" value="ADP-ribosylation factor-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7 13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="21"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="45"/>
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        </ligand>
    </feature>
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        <location>
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        </ligand>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023306"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00077919"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="21232" checksum="F8E6FC9B2423B669" modified="2023-09-13" version="1">MLSILRKARLKDKEMRILMLGLDNAGKTTIVRKIMNEDVNEVSPTLGFIIKTIDYEGERYKLNIWDVGGQKTLRTYWKNYFEKTDTLIWVVDATDRERLADCRHELKGLLLQERLMGASLLVFQNKSDVPGCMAEDDIRGGLQLDSIRTHKWHILPCSAMTGENLQEGLRWVVQDAKDRLFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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            <begin position="264"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO14316.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="46263" checksum="3E728D371D327034" modified="2023-09-13" version="1">MARSNLTGAGPLCATTNVTVQASPGIPIPVPATLLHARHVSRERCYEECWNARAALKKRVGNDLRVLPSLHNIRFFQSLPITPDLEARTDMGAFVRVAALCWVAELALAKVVTVSEGLCSTNLPAPTYGWVSTSGTTIPYTFPPTSTQTSSASMSASVPQVPSDEPSISVPEVYPTASEPSVEPSISVPEVYPTASEPPVSISSVVVVPIPSPPPSDSPPIIDPIYTSTSTSSVPPVELPSVIPSSTESAVEPPITTAAPELEPVPSEDPTTTSTTSEFVYIPAVSSNPPIVAPPAATGDACVQTAPEGSTIQCDAADGLTYCYQGINYGLQCGVQYDLIPINEIFFTYTAEECLDQCVGRPGCAGVQWNFAFSDCTLFEGLYGVSAELSPYIWFLYNREFIEDTYLPQQICPFNGCTEQPLKRELDAGESLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB90</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_02801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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            <taxon>Fulvia</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14217.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB90"/>
    <dbReference type="GeneID" id="71982679"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
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            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
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            <end position="474"/>
        </location>
    </feature>
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            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
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        <location>
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            <end position="644"/>
        </location>
    </feature>
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        <location>
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            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="835" mass="84671" checksum="CDDFCAC511551E7D" modified="2023-09-13" version="1">MDKLKKALSPGSSKDDEVLYGDAETRTREGAATTDAPAGHAVPHTVSPDAQLQTDKGQKDHSILRQILNPHGEKYDAEGYGSTAHVVGQGSDITGSNTGAGIGSSAAQSLPDRTAQTTAGPDSHLGRDAHVGPTTTTTTPTTTSSQPITERPHPLGGQSVGGDHINPISRPEDRAVQHGTDSHLGRDAGIAGGLGAAGVGAGAYSQHDRAGDHVTPTTEQANTAVVDRPHPLGGHDAPGDHINPISAPEDPAAASSTVGSHSQLGRDAGIAGVGAAGLGAGYAAHEHNQNQSTPLTGTTGAGTTGIGGSTVPSQLNAAPRDVQDATYTARQYNIPGDNCSGAPAEGYVHHTHGPHSTDIANRLDPHVPGEFPTESGVDRHGAGGSASAAPLTSIPDRDPSLTQAQPGQTGDHHYGRDAALGAGAGAAGYGAYEAAQGRGDTGPASKTIGPHDSNIANIVDPRVQPEPEKMKDSKTTGPHSSDLANKADPRVKETSTVGGGAIGTQSDHKPTVGEKLYPDSTPTDRPSTEHTGTGQDLKGTEDQHHGRDAALVGGAGALGGAGAYAATRDHDKPITEQLASTHGTQTQPAYHATTDSSAATQPGTNLPDSRHRNKEAAHAGEAGLAGTGAGAGAGAFASGDQSAAKKTGPAAGPSDTPVQHTGDPKSIAATHRDDKGHSSHTKEEEKEKKPSLIHRILHPGEGKEKEKESHHDEKKHDNSSGSHSHSHDEHNKLHKKALGEGKTTEEAAQHAGGNDGRVIEPHTGLPMNTAKYGTGQGGTDGAQNIAGYHETDPAIRNATTGTGVGAGTSAGHAQPGQEGVAGPDWDAIKKANTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBZ8</accession>
    <name>A0A9Q8LBZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759013.1">
        <property type="nucleotide sequence ID" value="XM_047907046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBZ8"/>
    <dbReference type="GeneID" id="71987776"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07898"/>
    <dbReference type="OrthoDB" id="3648004at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="78" mass="8135" checksum="8FE92E6738B0FB5A" modified="2023-09-13" version="1">MDAASFFVAQCGNTANCAGYAQAPQSAGGACYYIISDGRCNNQQSFGDMFRYYNTNGAGYTVGNGQCGFLLPIAGPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC31</accession>
    <name>A0A9Q8LC31_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759033.1">
        <property type="nucleotide sequence ID" value="XM_047907337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC31"/>
    <dbReference type="GeneID" id="71988067"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08189"/>
    <dbReference type="OMA" id="FYWLAKY"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF12">
        <property type="entry name" value="RFEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="931"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="17"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="959"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1106" mass="120856" checksum="A6BC6C2A17E48AD1" modified="2023-09-13" version="1">MDNYNPGYNPYPPPGTQNLAPQSSSQQQSSGQPSQQQQANQQQAQQQQQHQQAQQQHQQNGLSSFGNLPNHAQQAQHQQPSQSASHPTLPPLQGQNGYPQFGNMSYAHPGSQSHTPTTPRTPAQATMSANRPGNYSQHVSPTTSNGPGSMLPPSFPNNPYNASSLSQSMMYPSSTATSMPGTNAPIGLPNIRPMPPGGVTAPNGLPSLGGAGQLGQMGQQPSFMQSEEQPTHVVGSQGRRGILPSAPGRPNPPAQGSAQATKSMIPQKDADGKYPCPHCNKTYLHAKHLKRHLLRHTGDRPYMCHLCKDTFSRSDILKRHFQKCSLRRGNPTGANHLAHQRRNTNNGNRLSIGQQEGPIGLAGMQPVAGQEGFNGGVVSHSPTVNGDMSARTSRANSLITPGTMSHRNSLAGLGILGSNAPNADQMNQSSAPYQPGMNAYAMQQNSANGTQMPNYSYSQPPPQLNGYNINSSPYPPQPSFLGQQSSRFDNSQNNQHQQMPNGDGSGVDWTRMFNQGGQDGFIGSHSANASSQGNTLIKTEPDAKPAFQPDFNNDSFLGSLYSHPSGFGGEDTDGGIPGFPSWGMDDPLQAKVDNLMQHCFPHGTESSKGNLSAELMQSALKAENIKHYAEHYTSYHGHWPILHMPTFKLAEANNNLVLAIICIGAVYSPKLTVHQTRQMMEFVKATVFNNCSIYNRTMRGQTQGLGNQPYEIEELQALSMLHILFTWHGDPAQRQAARAEFPTLVSIAKAMDLCQQASPGHYAYSTLHASRAQHDQFAGQSWQWQSWLEQEKRNRILYHLVVTDAAMVMYFNCASNFDAFEIRLMLPADDAAWDASSPQDCANALGLNGPHAQGRNMTGTRKAVQPSFRDAMRTLMDPYSAFQPGSTNVYSKFLLVHALIVRIIACQKALLQNDQNFQGFNLQLHGSTPATPLSQNDWLEHNGGGSGNGSANNSGHGTPTGSLSPNNQNAAAHQEKKRVSQALEKWKRNWDHDMELQYPPQQSYQRRFGFSRDGVHFFYLGRSFLTSQQATDFNLPADVRFKRVMSLLKRIKGMVVGDNETKGQEIGSVGDIDDQYGMDSLTLDMKLLFKPYNSQLDSPVAGVQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCD4</accession>
    <name>A0A9Q8LCD4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759223.1">
        <property type="nucleotide sequence ID" value="XM_047906904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCD4"/>
    <dbReference type="GeneID" id="71987634"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07756"/>
    <dbReference type="OMA" id="FTPCLQY"/>
    <dbReference type="OrthoDB" id="5205629at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10146">
        <property type="entry name" value="LabA_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11297">
        <property type="entry name" value="PIN_LabA-like_N_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35811:SF1">
        <property type="entry name" value="HTH OST-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35811">
        <property type="entry name" value="SLR1870 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="3">
        <location>
            <begin position="185"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28081" checksum="34162FD0AA4530F3" modified="2023-09-13" version="1">MNNAKDNTAVLIDADNVSNKLIAGLLAEVANYGTAAFAYTTGKNATDGAMIIDAMDLLYTGRFASFCIVSSDSDFTRLAARIREQGVTVYGFGNRHNTHRAFVAACNEFIYLDALQMQPDEPTSLATPSPPTPSRPPPGSSTTQQYEQPPSTPQRLPVRPKVAYQDIPLRREPFPRQLDRAAMDGLKTAISSCAFYEEDYANLAEVGLKLVKVSPDLNARNYGYPRLSVFVKASGIVDLKMKSREVGAPIALVRLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCH2</accession>
    <name>A0A9Q8LCH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial intermembrane space import and assembly protein 40</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Mitochondrial import inner membrane translocase TIM40</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_03518</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
            <orientation evidence="3">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758579.1">
        <property type="nucleotide sequence ID" value="XM_047902666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCH2"/>
    <dbReference type="GeneID" id="71983396"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03518"/>
    <dbReference type="OMA" id="PRSWKNT"/>
    <dbReference type="OrthoDB" id="7481291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Mitochondrial intermembrane space import and assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039289">
        <property type="entry name" value="CHCHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21622:SF0">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="13" id="KW-0811">Translocation</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
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            <begin position="235"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
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            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013714"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO14213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="31285" checksum="7A6DCAC07C125420" modified="2023-09-13" version="1">MFRPAFRAASTARTVPKAQTVGRRFASTAPSTSRSWKGSAVRWTAAGAIVYYYNTATVFAEEPKYAINGPPETHSESETYQNIDSIAEKRRARARATQQQSQPSERTIVADGAAPDAEQVAAGGPEALEEEADQQGAFNEETGEINWDCPCLGGMAHGPCGEQFRAAFSCFVYSKEEPKGVDCIEHFKTMQDCFREHPEIYGSELDEEEVDAQIDAEGKEASTLVSEQPAPAAAIANASNATPSNEPEHRQRVRAAKDQVSQSTGPQDEVDQVVPKAWHDGREASTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDP4</accession>
    <name>A0A9Q8LDP4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitosis inhibitor nif1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759913.1">
        <property type="nucleotide sequence ID" value="XM_047907118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDP4"/>
    <dbReference type="GeneID" id="71987848"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07970"/>
    <dbReference type="OMA" id="LNGWGIE"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF11">
        <property type="entry name" value="PROTEIN DSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="162"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="237"/>
        </location>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="813" mass="90008" checksum="48215C34434AD618" modified="2023-09-13" version="1">MGPRPADLNVGQDRPDAFEPPRMFAHRDLPSPRAGEIPPALSPLDAFAMQSRALQRKFKEQQENGRRMSRLPPMMVQKEISNRPGYFRSMSGESKMTDLMEGDEESMPVSSHGKVPETRPTDQRPTNERPVSYYPRFSTATEPEEEEPPVPTPFFDAPGRRAQTPQQAAKAAADYFGISAPRASSPEPVDSTFVNVQAPSPNDYPSLTNSIDTISSHPRTMTIDSQRSNRSNTQTSERGLAVPQSPRWPRSPRSFQSIRSVPPDSGDEDGASTTGSHAVSSSRKFSGSSGVSRPQSPFSPWMQPVHRSPSMTSEYSMNGTQTPQRPVQNFSNFSRPMSSSGSRPSFDARPSLDGRPSLDKRPNLPLRQASGASNSTEHSSKSPLSRQASADDYDGNKDGEFSDIHTPALLEHSPSSFAFPIDKSGDDSGSHIYAKYALPRGRHIDRDSKAFRDSWIQKQFKWDMEHGASRPVQHERTHSDSPALEQAREQARERVAKAQADPRAETPDVSRPGRTVAAAPSEIRSQSVDPRALEKARQEAIHRSSPSVKTTSTDRTIKATPLHKKSPSADLTPEEHLEIGIACHESGETNKSTYHLRLAALAGQPTGMLLYAMACRHGWGMRENPEEGVRWLRKAVDITGLDVADAEEGMKSLDLAERKKRKAQFALAIYELGTSARHGWGCPKDKALAVRCFEIAGSWGDADALAEAGYCYTEGVGVKKDYKKAASFYRQAEKKGYSMAGNSWIYKEKYQDDTETQPKMPDTPKKRPGTSHSSKTEKPEERESRKDDKPAGRQRSRSIWGRSKKEKPPSLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE32</accession>
    <name>A0A9Q8LE32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759359.1">
        <property type="nucleotide sequence ID" value="XM_047907633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE32"/>
    <dbReference type="GeneID" id="71988363"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08485"/>
    <dbReference type="OrthoDB" id="3034343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="645" mass="72214" checksum="8972638A84F12D49" modified="2023-09-13" version="1">MNTSTDATPIGSRPYRSHKVPACDLCRNRKIRCNIDVAGEPCRFCRERHLSCEYTSKATVDDGLRPPPAKRRRTHADDHDVATPVKSTERGLAQFPSIAGTSPEESSIMLNPPMAEDIEVLEHYLSSASGASSGKPYRLVSSSTEKPIIYLTVPRRRKGLSAASDPGKTQREIIEQILGPNKEDVVALYFDRIHPAFPIVDAKTFYEMWHRDPSEISSALLCDIYTTAVVFWNTSERLRQYSKPDFVFLWNQAVAALQEDFLGPTISTVHASLLDLVGRPVLSITGNIMTLGKTVTLAHSLGLHRDPTSWKATSHEKDIRIRLWWGVYIHDTWSSLAHGTPPLIHAQTHDVPLPQASSLSASGATDAHKRSAQTFLHLCQLSTVLGDLLPFVYSLKPDKVELDRSLRRVECKLDDWESSLPPWLRRSNGELDLVNGASSLHFCFLSVKLLLKRIAYRVSIWVLRFSFHPRSFAEQATSMQADGVAAEARPYHLAMLRQSALELTDYVCFLKEPQLDDFWLPYTAHLLVSTTTILLRCLLESADVTTKRDCATMLVRVQARLECARAESNWDLVDFCLERCSEPVAKIATAMGITRHPTAGGMPTTELASVFNDTDTSMLSTLPEDFLLSVDSLDYPFDTLWDISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE80</accession>
    <name>A0A9Q8LE80_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_04397</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760141.1">
        <property type="nucleotide sequence ID" value="XM_047903545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE80"/>
    <dbReference type="GeneID" id="71984275"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04397"/>
    <dbReference type="OMA" id="YVSGWQV"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="207"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="423"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO15775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="537" mass="59553" checksum="929EDCCEC19F8C2D" modified="2023-09-13" version="1">MGSSDTEQSQFEQEVKHLKQWWTDSRWRYTRRPYTAEQIVSKRGTIKIQYPSNDLAKKLWNTVEQRFQNKDVSFTYGCLDPVMVTQMAKYLDTVYVSGWQSSSTASASNEPGPDLADYPYTTVPNKVEHLFMAQLFHDRKQREERLGKAPADRANAANTDFLRPIIADADTGHGGLTAVMKLTKLFVEKGAAGIHIEDQMPGTKKCGHMAGKVLVPVAEHINRLVAIRAQADIMGVDLLAVARTDSEAATLITSTIDPRDHPYILGSTNPALQPLNDLMLAAEAAGKYGPELQAVEDAWNAQAGLKLFHEAVADTVNAGVHVNKQGLIDEFNKQAKGKSNSEARAIAKGLTGVDVHFNWDAPRTREGYYRYQGGCQCAVMRACAYAPYADMIWMESKLPDFSQAQEFADGVHAVWPEQKLAYNLSPSFNWKTAMKAEDQQTYIARLGKLGYCWQFITLAGLHSTALISDRFAKNFAARGMRAYGEIVQEPEMEEGCEVVTHQKWSGANYVDGLLQMVQGGISSTSAMGKGVTEDQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEH2</accession>
    <name>A0A9Q8LEH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760333.1">
        <property type="nucleotide sequence ID" value="XM_047903675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEH2"/>
    <dbReference type="GeneID" id="71984405"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04527"/>
    <dbReference type="OMA" id="ARQYPQM"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="216"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="399" mass="44925" checksum="5E3B247970827C22" modified="2023-09-13" version="1">MWSLSGFISDVKYIVTHPDFTNLEVNTSGIVLMLVVIGIFSAAFYANIGDHSDALKDKVNAAIGSSSGVVHRKDDPPIPPPSVITALRIYPIKSCRGFEVSSTRLKRAGLTLDRNWMFISKEDKKFLTIRGDPSMTLIDTAIIEEGGEQMLEISIHNTDGRVTVPAFPSREWLESNTSLETVEIWENETDGWIYSDSINKIFSDFFSKPVALVYKGPSHRMVAINGRKELYGEDVPHHFADVMSLQVASEASMKDLNKQLGHALDSPEALTIERFRPNIIIKGRDDHPWEEDTWKRIRINTTISNEEALYKLDLDVVARCARCQVPNVDPDTAEKHKKEPWDTLMKSRRVDTGGPAKYKPCFGMMAIPKNEGKIAVGGTLEVLETTDKHWYNERAFKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF77</accession>
    <name>A0A9Q8LF77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760708.1">
        <property type="nucleotide sequence ID" value="XM_047904374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF77"/>
    <dbReference type="GeneID" id="71985104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05226"/>
    <dbReference type="OrthoDB" id="3946696at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="404" mass="45848" checksum="BFBE45024F249F1D" modified="2023-09-13" version="1">MTYYGNTKARILDFYITRDGKLARFSDSIPLEDVRAGYAYRAWLAEKQRRVQLYKAMLQQDDYTFANRATCLPAHVALSPYRKFPKLSDERKYASNYPPTKVTYSKAGFTDLPGELRNKIYILAGTAGHIFKLHTFLASDFCNGRPEAADLAREPLEQYRERVQQICPLMRVSKRLNAEVASMFFGENEFRFSRGLGWFFLESFLHGIGKVNVGRVRKIAVCDHWAAKDPRLVNSGRWYRDIVFVSRQRGMVGLKHNGVGDGGRDEAVQQCVRMLEEGGVLAELKLILPARFDVHNPFGLKFDGPKFQHGAPNIKLTHLAPQNHYWGPSPLKPETTETIHTLNYPARTPNSGSQIPHQAPRFSRIRQGSSLGIRGEVDGVQQESFRGRSWPHDVLSRTSSTTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFI8</accession>
    <name>A0A9Q8LFI8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ornithine aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05013</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760839.1">
        <property type="nucleotide sequence ID" value="XM_047904161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFI8"/>
    <dbReference type="GeneID" id="71984891"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05013"/>
    <dbReference type="OMA" id="RSAWDLC"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="481" mass="51914" checksum="D3652DEF92F548F2" modified="2023-09-13" version="1">MAPIAIEPETNGGHAIGTNGSLNAKATSFEPLHPSSGYHAASSSQAMSSESAYAAHNYHPLPIVFSKAKGSSVWDPEGKHYLDFLSAYSAVNQGHCHPKLIQALTDQASRLTLSSRAFYNDVFPVFAEKITTMMGFDMVLPMNTGAEAVETAVKIARKWGYKVKGIPQDKALVFGVQENFHGRTFAAITLSSDPESRDNYGPYLPNIGAVCPSSGKPIPFGDVKALEEALEKHGKETAAFLVEPIQGEAGIVVPHEDYLRKARELCTKHNVLLICDEIQTGIARTGKMLCHEWSGIKPDLVLLGKAISGGMYPVSCVLGSKEVMLTIEPGTHGSTYGGNPLGSAVAIKALEIIEEENLVQRAQELGEVFRNGLRDIQTRDPMIETIRGKGLLNAIVIDESKTGGHSAWDLCMLMKEKGLLAKPTHQNIIRLAPPLVISEDEIKSALSIIEAAVKELPTLKGEKEQKVIPPGEKNVHIGVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFX7</accession>
    <name>A0A9Q8LFX7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">60S ribosomal protein L11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761034.1">
        <property type="nucleotide sequence ID" value="XM_047904239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFX7"/>
    <dbReference type="GeneID" id="71984969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05091"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="7">
        <location>
            <begin position="27"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="8">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="21923" checksum="7BB8F2588DF9210E" modified="2023-09-13" version="1">MARGENSTQQADGQNVRTQGGKDKSANPMRELRIQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELRKRNFSETGNFGFGISEHIDLGIKYDPAIGIYGMDFYCCMTRPGERVAKRRRCKSRIGASHRIDQQETVKWYKNRFEGIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG60</accession>
    <name>A0A9Q8LG60_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761148.1">
        <property type="nucleotide sequence ID" value="XM_047904472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG60"/>
    <dbReference type="GeneID" id="71985202"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05324"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13721" checksum="7B673A8E8C360793" modified="2023-09-13" version="1">MLPLATWIFGPRQGPLFCHSYRGADAGGKYPPPDWKHWVWVWNQRKLQQYDNQRNEQDLGSVFDRAEIEVTTGGAGGLLGLDVLKIIQEPKEDGEAEERAEDMDEDEDTTDGADEEDAEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGB2</accession>
    <name>A0A9Q8LGB2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Aquaporin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04552</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761267.1">
        <property type="nucleotide sequence ID" value="XM_047903700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGB2"/>
    <dbReference type="GeneID" id="71984430"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04552"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO16901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="392" mass="43393" checksum="F7E376B98CF2D95E" modified="2023-09-13" version="1">MASLDGQTLKMGAQSDSDTEYIKSPDTPMPSNAMADLEAQQSRTFSNNSELDERKTTVKLMNKRKWLGLNPEAALDEEHDLAPHNDFLWGKIKIALKEPFAEMWGTFILVLFGLGGIAQVSLSKSPNGEFNPKYPGGWNYGGWQDINWAFGIGLMLGIYVAGNSGAFLNPAVTLTSCLLRKLPWRRLPMYWTAQILGAFLAAGVVYANYIDAINMTEGYGIRSVGGNTSTAGIFATYPADFTTRTTQFFEQFLASAVLMFMIFALQDDSNKGAFIASGAWFPLCLFFVMFGIATCFGWQTGFAINMARDLGPRLWTYCVGYGTDVWSAGGYYFWIPMVAPMVGCLFGGIVYDLFIFTGESPVNQPYWGIGQVINPYGAMKQRLRKQKQEGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGH1</accession>
    <name>A0A9Q8LGH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761562.1">
        <property type="nucleotide sequence ID" value="XM_047904730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGH1"/>
    <dbReference type="GeneID" id="71985460"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05582"/>
    <dbReference type="OrthoDB" id="4937900at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="409" mass="45438" checksum="E09C44B33B5E7E80" modified="2023-09-13" version="1">MSASPSGSSDPKSPSASMVRKTHTKSRKGCQQCKRRHVKCDETQPRCAACSRLDIVCTWAAPKTSTTSLTPPPSTPGSAAGAQAGASTPAGPWELDMESLKLLHFWTTHTSFTPAVKAEQIIYQTVMVELGFKYPFLLHAILAVSAIHKAVLGPANNEDLVYRSTCHMDVAVSELRRQIAFPDPVACSAVFGCAGLVVMHSLGLCQANPPKDPLGEMCHWIRLVHGSKATVQQNWIRLITSDMAPIVFSVDWSKTSGGDIQEIMDLETLIGQMCPKDSPAYDAHFKAIERLHVVFKNTHYYLRSGELNSVAITMSWVACLEDTWVNLVEERDPVALIIVAHFAVLMRLHEKTWFWKGWSRWTLDAIVTQLHEDYRPWIAWPIRQLQNGLEPTSDMNSPVDRSQTDTAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH25</accession>
    <name>A0A9Q8LH25_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761680.1">
        <property type="nucleotide sequence ID" value="XM_047905654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH25"/>
    <dbReference type="GeneID" id="71986384"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06506"/>
    <dbReference type="OrthoDB" id="3621149at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="12035" checksum="58FFC4F693E4995D" modified="2023-09-13" version="1">MDKPSLCLCFPCILHYLEGYIYPRSEQQHYPVLQRKGFTREQQQAIAEEWYWVAFERETAVKDYMNGFVTFHDGCYWRPPPVWEPSSSSTPGASSSSSRSTTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHS5</accession>
    <name>A0A9Q8LHS5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762252.1">
        <property type="nucleotide sequence ID" value="XM_047904619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHS5"/>
    <dbReference type="GeneID" id="71985349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05471"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16280">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051453">
        <property type="entry name" value="MBL_Glyoxalase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233:SF3">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="115"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="37717" checksum="3F33F39DC0D452FA" modified="2023-09-13" version="1">MSIKVAARGFLQELNMLTHFLSVATAITTVTAQRGRPTNFSELWNITTYPDAQPANVSQYLNEASHLAGQDLDDHFQRRCIVSQLYDDIASYAQAPGFVPPIEVFDGVYFVGQSAVSAWAIATSKGLVVIDALNNAEEAEQILISGLQAFGYNGSDIVAVVITHEHFDHYGGALWLQDTYDAPVYASELAWQAMEVADGGPRRDQVVDDGQTLDFGNFSMQFVATPGHTPGAMSLIFPVQDHGAKHLAGMNGGAGIASNTTAKANQVESYAKLASISAEAGVDTLMANHQTQDRSLTNFDLLNARECDESGCKQENPYVIGTDAFVRYLQVQSLCVRVEAARDGQTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ04</accession>
    <name>A0A9Q8LJ04_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762639.1">
        <property type="nucleotide sequence ID" value="XM_047905558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ04"/>
    <dbReference type="GeneID" id="71986288"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06410"/>
    <dbReference type="OMA" id="NRECVLG"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052780">
        <property type="entry name" value="AAA_Catabolism_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="662"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="766" mass="84813" checksum="A3828F740B3B7E5C" modified="2023-09-13" version="1">MPGTQAVTKSESISRDDKKEKRTSRACLNCRSRKSACNLPTDESGQITTPCERCKASNLECVIGSSNRGGRRVRKRTLDHAKILDDNPRKHLRQSSEVTAGADERYQSEELSYSNDREVWPTDYHNGVALSDTLNPSTPRIMLDPALQAADVGARDSYLGTTQATRESSTLSTSNIAFNDLQNPSDALGILAQIASHGENAGPALVPSHGNSSYGQGQSQMDYVLVRDGRLSLSKIIQLLQRYKHYYHPYFPIVPEATLDATNLSKTARDEKHLLTAVLVIASRDLIDEPTIFIACSEYMRSLVSVLAAGGEGKVEAVEALLVLAEWTPYTSRSDAGHVGRGEEDREAWMHVGNALRIGYFLGLDRYSFQVRGDDVKDPQWQRKRLVWTACYISDRQISIRLGRAFWSRGPGPLTTLSKADFPMLAPTAPGGEDYASIFQATLELTLLFSNVHDVLYSNPGNSMRSHLSGGYIKYIDDFRSAIYGWKSVWGTLTCSGPLKATLLMSYDYLRLYTNAFAFHATVKRALPQIQQGQENRRSAHPQPGRVFYNNVGAVGDARFIYEGLDAAKNLLSMVNTFVDPEKSLRHMPLRFYLYCIYSGVFLYRARCVGVLASDEEQSVRSLVQETINRLERSAIGTHHPGNRYSQLLRLLWDKVERKERKGNSSTATIANPYRPGSVGGPTPNSNASGGPTSAALQQDNSPAFTEPMGDFSWTDLDAIGNFAINGNGGATMNDAEWWSGFLPADSNNFLFETLPGMDDWNLGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJY5</accession>
    <name>A0A9Q8LJY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762449.1">
        <property type="nucleotide sequence ID" value="XM_047905448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJY5"/>
    <dbReference type="GeneID" id="71986178"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06300"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="168" mass="18626" checksum="B9B4DC94A2272721" modified="2023-09-13" version="1">MSETQDTAASPNFALLDIDMHTLITRDFTFPASISEKEQEFIAHIRKALRDMITAINDRNFSNEVFARILGPKSQEILGRANIRGFAQDEPTFWIKLGTVSVVPDVRKNTAQTVYAMELHGVPERVTRPAVTQQEWKKSAADGRSGTAQCAQGTKHAVSTPIPVRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P343</accession>
    <name>A0A9Q8P343_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Scyllo-inositol 2-dehydrogenase (NAD(+))</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00538</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755780.1">
        <property type="nucleotide sequence ID" value="XM_047899686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P343"/>
    <dbReference type="GeneID" id="71980416"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00538"/>
    <dbReference type="OMA" id="FLERYMQ"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="136"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="356" mass="39213" checksum="08B560E3C5760234" modified="2023-09-13" version="1">MVRKLQVAVSGLGRMGARHALHFLDRTPRAELVAACDPDPKALAWAKQRLEPFGVKIYSDFDEMLKHEGLEAVVVAGITTEHAPQSIRAIDANKHVLCEKPLSTSLEICEGVVEAAKQKPELTVMCGFSRRFDASYRDAASKVESGNIGRVSVIRSQTADKHRDDDYFVQYAKHSGGIFVDANIHDIDLAFWYFGSDSIVKSVTAVGINARLQGLAQYGDVDNGVGIVEFWGGKIAYFYSSRMMAAGQTDTTEIIGTHGKIVVNGNPAQNLVEHHEATGIRRDVPQTYYDRFEQAFVTESNEFTEVILDGKRPPFQLNGAVAALKVGDALQESLRTGKKINFNEIGERIVESKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Z3</accession>
    <name>A0A9Q8P3Z3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
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        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_02080"/>
    <dbReference type="OMA" id="FKSDAEY"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="108"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="389"/>
            <end position="465"/>
        </location>
    </feature>
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        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="589" mass="65589" checksum="D0A85E797CB7CF9C" modified="2023-09-13" version="1">MAADIPIKVKHQGKSYDVEVNPESTGEELKMQLYSLTNVEPENQKVLAKKIVKDDTPLSTLGLKPGAVITLIGNPSANVVFEVPKEKMKFAEDMTEAELAQQDGAIPAGLQNMGNTCYANATLQTLRAVPELVEELKAYKPSAPSAGPSSSSSLFTPEQLAQHGIGGLGGGGDLTSALGDLYKQMNETQQGFPPLMFLTTLRQKFPQFAERAKNGQGYAQQDAEEVWTQLIQTISQSLKLKEGDDAAQGFNSWVDKYMGGKFEMKTTCDEDPEEEAVTNIEDFNDLKCNIQVDTNHMREGISIALNEKLEKTSPKLGRTAIYTRQSRIARLPKYLPIHFVRFFWRKDTGKKAKILRKVTFQHEIDVTEFCSEDLRKKLVPIRDKIREVRKEEEDVERAKKRQKRMQKESEENGDSNVRSDEPLQKRKEKEAERQLKATGPASETELKAEKKEAGGSEDTMMGGTEEKFKTDEEIEAERAASILAAKKELLALVHPDLKKDSTAGQTGLYELRGLVTHQGSSADSGHYTAYVKKAAAPGKSEDGKWWWFNDDKVSEVESEKIETLAGGGETHSALILLYRAVELPKVEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P425</accession>
    <name>A0A9Q8P425_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P425"/>
    <dbReference type="GeneID" id="71979933"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00055"/>
    <dbReference type="OrthoDB" id="3648311at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="34174" checksum="993DCA82C6662D40" modified="2023-09-13" version="1">MEMATNNQNKRKRGAATHVKIAEKAPTRTNPTRTNPTRTATTKTLIAPPDLSSEDESQPKRPKNSKKPRKNRANPSTKHFRFLELPGELRTNIYDLVLADSSVTLRRSARRRKKPTKRNDEDSPNWQDNIVVASPLTQVNKQICAEFFHAAAISADIRTTVVDFEFGHIITFLNRLTEGLLDKMKAGEEDKAPKRNFTITLQHLDKHVEDDKTLRRWLNRMEVPEKKGTNIDFRYICSPLPVRDLSWQIPSHLVALFGGALSIPSPTLPRRIIDGAPTYSEGGRGAEERAKIVGAADLAQGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4P6</accession>
    <name>A0A9Q8P4P6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757671.1">
        <property type="nucleotide sequence ID" value="XM_047902630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4P6"/>
    <dbReference type="GeneID" id="71983360"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03482"/>
    <dbReference type="OMA" id="DIHARPC"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="188"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="405" mass="45512" checksum="1E99D403B0DD1450" modified="2023-09-13" version="1">MTDTPQSGAIGNENLRPKMNGAPDDNSRPASFVSAVSSQLQTTDTPASSATQTTAGAEREEEEWTPPTNGPLKTPIPKHSRHSKIAPQPKLTAEQESKYTTVLEQVSQWTTIPTSTAKGAPQAPLEEHERMFLTRECLLRYLRATKWKPVDAVRRLQETLSWRREYGADTFTHDYISPENETGKQVQLGFDNDGRPCLYLNPGKQNTKMSDRQIHHLCYMLDRTIDMMPAGVENSALIINFQGAASGTVPSVGQARAVLNILQGHNPERLGKALISKTPWYVNTFFKLVSPFIDPVTREKMKFNEDLRKYIPVEQLWKDDGGDLNFEYDHAVYWPAFDEECKKRRESYRKRWEEGGKKLGEYEEYLRGGSQSSLQQISGQADEAATQPQSQDADMAAEGAAKLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P505</accession>
    <name>A0A9Q8P505_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_03648</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758001.1">
        <property type="nucleotide sequence ID" value="XM_047902796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P505"/>
    <dbReference type="GeneID" id="71983526"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03648"/>
    <dbReference type="OMA" id="DTCVWAY"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="67817" checksum="181B7229635A93B4" modified="2023-09-13" version="1">MIASKRYLAFAAFAIFVLFLVAHFHDSIASQARVRYDTFFPSASKHHADGRFHWADVPVQHPVESLTSLPSGKPKKLPRVQYDFKDQSQALKQKPRQAAVKATFVRAWKAYKQHAWMKDEVTPINGNFKNTFGGWAATLVDSLDTLWIMDMRDEYEEAVNACMDIDLGISTTDTINVFETTIRHLGGFLSAYDLSGDRRLLEKAQEFGEMLLKAFDTPNRMPITRWKPQEALYGKQEADGVVLVAEIGSLTMEFAHLSQVTGDMRWYDAVDRIMRIFHKQLDETHLPGMFPVVVNAKELDFTQDTFFTLSAMSDSFYEYFPKMHALLGGTEPMYTKLYTRSMQTAIKHNLWRPMVPDEADILMSGNVKTEMSQPPTLEPQGQHLVCFAGGMFALGGRLFEQEEQVKIGQKLTDGCVWTYKALPMGIMPEVFNMVPCPSRCGECKWDEQKWKTEIGKVNDGTADVEEAITELRLPKGFTQIRDRRYILRPEAIESVFILYRATGQEYLLDAAWDMFQSIINATKTPLANAALADVTYEPAFLEAQNAQVKMDDMESFWMAETLKYFYLIFSETSLISLDEYVFNTEAHPFKRALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P568</accession>
    <name>A0A9Q8P568_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="18">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CLAFUR5_03217</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>7-dehydrodesmosterol + NADPH + H(+) = desmosterol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17737"/>
            <dbReference type="ChEBI" id="CHEBI:27910"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:46741"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>cholesterol + NADP(+) = 7-dehydrocholesterol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23984"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.21"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="21">
            <dbReference type="Rhea" id="RHEA:23986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Steroid biosynthesis; cholesterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 23">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="18"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757970.1">
        <property type="nucleotide sequence ID" value="XM_047902365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P568"/>
    <dbReference type="GeneID" id="71983095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03217"/>
    <dbReference type="OMA" id="WGKPAEC"/>
    <dbReference type="OrthoDB" id="5326588at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1630:FF:000004">
        <property type="entry name" value="7-dehydrocholesterol reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="5" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 23" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 23" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="12 23" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 23" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="17 23" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 23" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="16 23" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00039984"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047826"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="UJO13604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="452" mass="51639" checksum="10A9A52773789A32" modified="2023-09-13" version="1">MTVEILATLSPELAKPVLWGRNTKAKLENTLGCLGMVIGCPILIVLNWTALEHYNGSLLETFQAAFDQGALPFLLNHLPRPSTPAIAGYAAWLLWQALLYGILPGTTCYGQRTPGGKLMQYTANGLLAWAITHVLYFTASAAGVLDAAIVAKHWEGLLVAVNVYGFFLAALAQLKGYYFPSHPEDRKLSGSWIYDFWAGVELNPRFGTYWDFKFFHNGRPGIVAWTLVDLSWAAYQYQTLGYVTASMWIVLVLQAVYTVDFFWHEDWYTRTIDISHDHFGFMLAWGDTTFLPTFYTLQAQYLARYPTHLTLIQSAAIMALGVTSYIIFRQANSQRDYVRRHNGNAKLWGRPATYIRVKYQTSDNKTHDSLLLTSGWWGVARHANYLADLVQSWAFCATCGFTHFLPWSYFFFMCILLHHRIGRDDRRCRNKYGEKWEEYCKLVPCRLIPGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5K3</accession>
    <name>A0A9Q8P5K3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_03440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        </lineage>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71983318"/>
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    <dbReference type="OrthoDB" id="3884299at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <location>
            <begin position="236"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="41095" checksum="9CA82D94D3E3D2C0" modified="2023-09-13" version="1">MQAMSIRHPPKPLVKNCALVCCSGFVRKEGLIDISEPNLKTAIPPVVSKCTFRGYPKIDYAVLDQALRLLSNLIEQSLPMYHTIFFGQTRLLRQTPERRDYEFINEVQMLSEKQKDQTRRRLEEMLDPVAVGWHVRAYDIYRLSQQEFWDTDVKKLGIRALHPKLRTGYRYSTPSGGKFHPHKCSLLEDRRIDGRDTKVEVFDLRGVPDGYSLSAWGLIEEAQSEEFAHVPRKFKVEEVDERPAPHTAPQQTSNRPMAPMQTAPRQPDGYTGAPRQVPGSTAAALGGDYVTELTRIIAARAAEYPQNSDPQPVDSEPAGFMDAQFDAMFDITAPLAAPAAPPSAGVNVARVEEDEDAIDIDMFGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6D9</accession>
    <name>A0A9Q8P6D9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08423</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759217.1">
        <property type="nucleotide sequence ID" value="XM_047907571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6D9"/>
    <dbReference type="GeneID" id="71988301"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08423"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040385618" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10695" checksum="C87B069FA8B70CF7" modified="2023-09-13" version="1">MKFTLIIASLMAIITYSMAVAPAVLFQRTPQRFQCYQVTCYKPNFGDDQCKRDCGGIECSAQTNKCVAGSKNGTSTSTSTSTSTRASVRASTTCNDMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6U5</accession>
    <name>A0A9Q8P6U5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_08464</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
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    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759682.1">
        <property type="nucleotide sequence ID" value="XM_047907612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6U5"/>
    <dbReference type="GeneID" id="71988342"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08464"/>
    <dbReference type="OMA" id="MLDMNVK"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO15316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="32900" checksum="0312FC5B8B7F7599" modified="2023-09-13" version="1">MPICIECRYPVSNLYTTYSKADDKALGKGVRLTQCPRCKRFADKYVEHDFVVLFIDLVLIKPQVYRHLLFNRLGREDDKFDPSILRLGILLLLFDVYLTWARIEKATPTSPSLPLSPPPPPPLPPFPSGSNTTSLPDQDSDHSSFLATQPILLQYLFFLFLCTLETASFHLPIRWVLSLKLPLIPHYPHAALISTALLVSSFTKLFPLMLLVWKYDLPSSASAVSWAVIINNVAALEILLDCGYVRAALLAGVGAVGRAGVGMGILRAVGVGGGVAAAGVVETGDLIDVWRRLMETVGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P761</accession>
    <name>A0A9Q8P761_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04639</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <end position="244"/>
        </location>
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        </source>
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            <dbReference type="EMBL" id="UJO15718.1"/>
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    </evidence>
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        </source>
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    <sequence length="408" mass="43750" checksum="05A4C90FAB4811B2" modified="2023-09-13" version="1">MSFPNFEGGAQPPQQDGQEQGGFGGAPGAPQQPPPMGQQMDPNQQQGQFPGGPQGQVQGPPGSAQGGDQKTTLWMGELEPWIDENFVRSVWFGMGYQVNVKMIRDKFSGSNAGYCFVDFENPEAATRALQLNGQVIPNSNRQFKLNWASGGGLADRSRDDRGPEYSIFVGDLGPEVNEYVLMSLFQGKYTSCKSAKIMSDPISGMSRGYGFVRFADEGDQQKALHEMQGVYCGNRPMRISTATPKNKSGGGGPGGMPGMQGGMGPGAPGGVYAMGAPPMGYYGAPQPMNQFTDPNNTTVFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVQRHAAEMAINQMQGYPIGNSRVRLSWGRSQNNSGPAGTPYRPAPPPPVYPSMGMPPQHPFGNYAPHQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P790</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <source>
            <dbReference type="EMBL" id="UJO15854.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="23444" checksum="930851293551A196" modified="2023-09-13" version="1">MAHQRVVAFLGIEDSLWKLAILQELVPNPIPPTGDSHVEQLRAAVQGLQDMQDRFRENTERAINEGGSAAFEEELGNGVREMLQFALDHIDVLEAARDDMSADDEDGVDDDTIAEIKAKMPHVDFDISAEKPRRGISAAQFQLEKEQLVEDCAICYVEPPVDNEPLETACGHIYCAECLVRWCLEHNTCPDCRQEALLEDMVLLDVVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7I4</accession>
    <name>A0A9Q8P7I4_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">Bul1 N-terminal domain-containing protein</fullName>
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    <organism evidence="3 4">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71984174"/>
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    </dbReference>
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        <property type="entry name" value="Arrestin-like_C"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31904:SF1">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="105"/>
            <end position="162"/>
        </location>
    </feature>
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            <begin position="348"/>
            <end position="377"/>
        </location>
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        <location>
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        </location>
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            <end position="376"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Pfam" id="PF04425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="517" mass="57028" checksum="883E2FC3AF972EAC" modified="2023-09-13" version="1">MSVPSEHSSDGHNMQSRLRNLYQAHKPEIQINLHRRRSVYSTLDKIEGVATIVAPTDTSFDDIEVEFVGTTRTYVERLTTAAAISGKSEAFHQFLKLKQPRLHEHLPEDRTLKAGQKYELPFVFVVPQQLLPRICQHKAANQSLRDTHLQLPPSFGDKEAEWKAESVDDMVPEMASIRYGVFARISKDKEEGGDTVKATIASKARRVRVVPATQEQPPLIVENDSEYTMRKERTIRKGVLQGKLGTLVVEASQPAPMRLQAHRTGEQQPSMATVVLRFDPVDTKSPPPRLGSMATRLKVCTYFASTARSTFPTKQASLLDLSQGMHSEQINLSSRCVASVEWTKHDGSKPVLERRDSGLSATGSTPTTTTPEPSETYKGKSYYTSKILVPLTLPSTKAFAPTFHTCLVSRVYQLKLELGLHTAGIGGTIDLKVPIQITSHSSGDASPRSGSIDSNMEMIMDDEYSDYFQSRTIHVPDDALLGRSRIGVQVVGGGGDDAPPGYSFYASQTGSLTVPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7X8</accession>
    <name>A0A9Q8P7X8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1446 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">CLAFUR5_04489</name>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF1446 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="8"/>
            <end position="458"/>
        </location>
    </feature>
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        <location>
            <begin position="507"/>
            <end position="606"/>
        </location>
    </feature>
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        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="68117" checksum="1D35855A71A398DD" modified="2023-09-13" version="1">MATPRRPVRIANCSGDPGYHVYNQAKHGPVDVITGDYLAEINLGNDAEAMSKGEHPGWIPTAWDGLQQSIELIAEKKIKVVINGGALNPKGLAMKTHELIQSKELGLKVAWVEGDDLLPRINEILSNKDSLPHLDKDNSDIKLSKDTGVFLTDRDCNRILSANAYLGGRAIRKGLEEGADIIICGRVADASPVIGAAAWWHDWASDDFDALAGALIAGHLIECSSYITGANFAGFDQYPIEKLLDLGFGIVEVDGHGDCVVTKHETLNGFVTADTVKCQFLYELQGNIYLNSDVKADTTKILIEDVGKDRVKVSGIKGYPPPPTTKLAIFYKGGWQCELLFNATGYNTARKFQLLEAQHRKKLTDWGIIDKFDILDYQWVGRPESNPSCQLASTTYIRVFAQAQDKDTVAKVMSAFATNAMQHFAGFHSSLDHRTAAPKEFLAFYPGIIQQSQLDEAVCLIPPDSNQEPQRHVVGPPSKSEALQPREDYETARTSSLESFGSTVMAPLGDIALARSGDKGANVNLGIFVHTDEEWDWLRSFMTKTQMKKMMGSDWQDWYHIERVEMPNIRAVHFVIYGPLGRGVTSSRLLDALGKGFGEFIRDVHVPIPSKFLERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P842</accession>
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        </submittedName>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8P842"/>
    <dbReference type="GeneID" id="71984935"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05057"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37562" checksum="45597C7DD43CB8FA" modified="2023-09-13" version="1">MATRSTTQPRTHWLYWPLEDVVALKYPNQVDNGSIKTFCLKLCIFPNSDILLFKPHGSDQHVIPVRDIAAASPGLRDHGVNSIIEEMLQAQIQDDELPDLQYLDLAGSEPLVELQSSFNGYDKSVVMDRAVLTILLSSSSSSVRADSGINGATYASVTNTSFKPDGALTQAVADEEGLEKAIVKRQHYIDQQQRWLTADAYLTTLHDFCFNTIFVACYLRSRATGLESCTWGCLLRRKTNGPGHGLYIMPATVAEAHAVNQGVNGPAEIQHRVRPSDVNLTRYEVLGAFNINGGLRMHGGRQEYARILVSQTGRMHLRWLPRSGNKDMRILSAAGVPWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8F7</accession>
    <name>A0A9Q8P8F7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family domain-containing oxidoreductase himF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903583.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71984313"/>
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    <dbReference type="OrthoDB" id="300709at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NmrA-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="2"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="270" mass="29694" checksum="D2C740486BF99C6C" modified="2023-09-13" version="1">MQEILVIGGTGAQGLPVVHSLSGSGRWSVRVLTRNENSERAQQLAKLPNVTLIQGQQDNQKDLHRAFKGVYGAWVNTNGFTNGEKNELFYGIRAYEIARHEGVKHYVYASTDYAVKDCDWNENYHWGHNDAKGRVADFILAQDQKGMKASSIVTGPSMDMLFDGMFTPAEQEDGSFLWANSGKEGEIPLIALEDVGPFSMWMFNNPAESAGLLLKVATDEVSFADIARTFTEVSGKKGVHQFVEISKFVKAREPFPGAMANFAAGPQEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P981</accession>
    <name>A0A9Q8P981_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762381.1">
        <property type="nucleotide sequence ID" value="XM_047905768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P981"/>
    <dbReference type="GeneID" id="71986498"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06620"/>
    <dbReference type="OrthoDB" id="5318346at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080">
        <property type="entry name" value="SRR1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080:SF1">
        <property type="entry name" value="SRR1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="2">
        <location>
            <begin position="85"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="28925" checksum="7F571BC9A8A8258E" modified="2023-09-13" version="1">MADDGWTQVPRKSKPGVNFSRHLPASQTPTTTTTTTSNIDRTNPPSRDITLAQITADYQRKLKTWQQSQCRSATLRILDRIRPDSGWNIRTAVCLASGSFSRDNLECRRRSMWQIVVFIDLAKHFVEGVKVVAQEPAYTDLDRVFLQTLHIEALEVDFEKGSGLGQAGKHLGKEAFVFEPFLDMDAVMMKEIVEADVALYVGSSIRGLMSRTNEVGALAKKFSESHRMYNFPEFEVDPNVLGGMGIYWKEEQEDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9E0</accession>
    <name>A0A9Q8P9E0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762561.1">
        <property type="nucleotide sequence ID" value="XM_047905200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9E0"/>
    <dbReference type="GeneID" id="71985930"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06052"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10174" checksum="0349F91C6D20E51E" modified="2023-09-13" version="1">MLVGYTSKPLATTDRLAYPGLIPPHHPVRLQSVPRNGPEQWLHFGIAGVPHVSHLSSDYTRIAHEGILMTKKHGSTYSVLIQRSHIRMGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9F7</accession>
    <name>A0A9Q8P9F7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent mannitol dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.138</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05578</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-mannitol + NADP(+) = D-fructose + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16765"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16899"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.138"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:16766"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:16767"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.138" evidence="5"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762262.1">
        <property type="nucleotide sequence ID" value="XM_047904726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9F7"/>
    <dbReference type="GeneID" id="71985456"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05578"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF14">
        <property type="entry name" value="DEHYDROGENASE ARBD, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="472" mass="51617" checksum="4CFA8415F8F8515E" modified="2023-09-13" version="1" fragment="single">FQSSTHLKDPPSLLPRFDIIPERPCTSYDTRTRQFLPEYVLPVLRILTLTPPTSTCVLYTIHLTFTPRVTLALSRSSRRKASSLKQQLQRLTSPRNTITITPTASIMFKHNLLRQVSRASTTAARPPTSAFLSRTATRGIRVTPNVREEEKDKHDEYSTAGKPGAFKHEGEFSRTDKTIVVEYPEEGDLPSSKPVQGRGGFHFKRTLASFTLEDRVGVVTGGARGLGLVMSQALLLSGCRVAIVDLNKEEGEKQAQLLMETFKKENPGATNVPEVTAHYCDVSSPQSVDAAMEEILASHGKVDHLVTSAGFTENFDAIEYPHDRLQKLWGVNVDGTYIWACTVAKHLMARKAPGSVVMIGSMSGAIVNVPQPQAPYNAAKAAVRHLASSFAVEWAHAGIRVNCISPGYMLTALTKKILDDNPELAQKWTSLIPQGKMGRPEDLMGAVTFLLSDAAGYVTGADLRVDGGYTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Y3</accession>
    <name>A0A9Q8P9Y3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UBX domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762951.1">
        <property type="nucleotide sequence ID" value="XM_047906682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Y3"/>
    <dbReference type="GeneID" id="71987412"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07534"/>
    <dbReference type="OMA" id="NKDHTDK"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14348">
        <property type="entry name" value="UBA_p47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.210:FF:000002">
        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054109">
        <property type="entry name" value="UBA_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22566">
        <property type="entry name" value="UBA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="318"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="397" mass="42398" checksum="4692059B13CCB62F" modified="2023-09-13" version="1">MADNHDDLIAQFSSVTGANPSIAQNALGAANWNLEQAITLYYAENEDQPNASDEDIPEAPAAQPTQPQPLSSSSSSKPKAATSGNSKMKTIRDLQGGGDKGEDEDKPQDMFAGGEKSGLAVQNPGEGGQPIDHFRNIMQQARQNRERPPGADGEEEETPRSTAFSGRAQTLGGDDAPSQVVEDPNAPPPSSSDRQRPPRVSRTLHLWADGVSIDDGPLLRFDDPANEHIMQEINQGRAPKALLDVQPDQEVDLNLDPHKGENYVQPKPKYKPFGGQGNRLGAPTPGLATSSGAASSLSSAAPPAAASQPATQQPAIDESQPTIQLQVRLGDGTRLVARFNTTQTIGDVYSFVDRAASQPRSYALMQTFPSKELSDKSQVLGEMSDFKRGGTVVQKWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAE8</accession>
    <name>A0A9Q8PAE8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763227.1">
        <property type="nucleotide sequence ID" value="XM_047906738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAE8"/>
    <dbReference type="GeneID" id="71987468"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07590"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF7">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383895" description="DUF1996 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="4">
        <location>
            <begin position="34"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="752"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="720"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="416"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="611"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="779"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="806" mass="88126" checksum="4F1891F3045316B1" modified="2023-09-13" version="1">MKSFTLATALAYAGGAAAFWRMPCRSETGFARIDPLVDPGDIADHVHTITGGGNFGPETTFEQLTAPGSCTSCAVKQDHSAYWTPALYFQHANGTTVMVQQVGGMLAYYLYYLDNVKAFPEGFAMIAGRPEYRNFTGPFPDEELSLWPTDPTNQFFLEQRALGFNCLNYQRDPEASLYRHQFPDKSYMDSNCVDGMRLELAFPSCGKKGVLDSEDHRSHVAYPSLVKEGNCPDGFDVHYPFLFFETIWATNEFAGVDGQFVLSTGDPVGTGYHGDFIMGWESEDFLQSALDTCKNPSGQIEDCALFTIQKDADADECFFDVPEHLKKDNCHGPRDGLPVGVPVQYGPEPATKYPVPGRQGKATTAISHTSAPPTYSQSAAPYSPADPEKTKTADAGIIQGAASAVNDILGHGAKPSTTSSCSSSTSSSSSSKITQAPAYSSASKHDNIFLYQYLPDWLSIMGSPPYQQLPITHKDFTKRCPIAHGTRRCRNMRSCDYESHKKANPNGSKEVEYLIHNLTGRAGELSLETRRTMTRRLHELSDCNKHLDAVCVEESVKRTLEQLERAERFIASTTAVIAVDHPRVNLAPIIQQRETPPVHFATVTGPPTPPESARSSLESAEATTPPRPSTAEQARGFWGVPPPITATPRSLKTKPQPLLQTPLRTGNHPASPSASPPPPPAPAPRRCTTGPLPTNTAALFTTVPPVPSAEPAFLPYPIRIGQLEAENSRLREELTQANRRAETERDIAKAARRAAEMWKKHYESKQPPPPPHEKAITEPSPPSSPTPIPSFPTHHVLPESSSNKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAJ2</accession>
    <name>A0A9Q8PAJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763299.1">
        <property type="nucleotide sequence ID" value="XM_047906203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAJ2"/>
    <dbReference type="GeneID" id="71986933"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07055"/>
    <dbReference type="OrthoDB" id="5426798at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="284"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="160"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="912" mass="102251" checksum="F2758391DE5A5270" modified="2023-09-13" version="1">MFSSTAAEPMRAFPLHERQPSDQSRSYANPPRHLVELPRPLEPRPTHQLHSAHSEASRDRRRSDGFGQPAPMQPEYRPQTQNLPRLHDILTSGPSAPSPPTYGGSWNNTAGPPALQQNGDGHYSHNGWHPPMVEPPRGHESSYHSQQGRRLELPILETSPVTRHDSHVPQQSPYHTYHEPRREYDPRRERPHEPPSASYLPNRAEEQHYRSPAGSIDRPRTHAFPPNAPESSKKYIGVREVPGEGQFHLYEGGYRIPTSVDGENVNPAWGLTKANKPRKRLAMACLDCREKKIKCEPGASSCLQCEKAKRPCRKAPTHQSQSEPGTTPVWQSSAGSPVRNTGFPDPNHANIRELEFDPSTKRRTLDDDSPSGGPAKKHRSTSPVQAVNGNGLPGHGSASLHTSPVMPRSPGKVVCLEEDPYAAEPEMTLTLLEYYLTDVNDATYRMFPRHHLMHWLRAYPQKSQNERMVLYAILALGSTFADDQYSGFGKHCANIATEAVLSKSGRSTMAFIQTRLILGLYHFARGANSAAWEYISAGVSAGSYLCYHTEDGCAEDETAGERRSEFALSKEQLIECKRRTLWSGFIMDRYCGATHTMINNQDIFIRLPCTDDAFERGFASNAPYHNNGIVDPSRAILTASSALSPMAWVILISAIWGDVVNFINRSVHRAPNSYEDQYEKFYDDTHAALQGWQSRLPDHLQFSRPNAERSIQGGYAGPFVSMHILYHLSFLKMNRFVRHEYISKSIARNVRGTHRHALEILQVMSCLRAANDGLAKENHQTFSLTMSFAGYAILAAIDVVGAGGLDSGLTTTLDLIGCGLESLRELGRYWNSARDQHKACEKRFYQIHNVLKHPFTARSGCWLGREWGVHSSLEREFDLKDDCIYGVSDRDYFDALKEDTPEGRPNGTLRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB47</accession>
    <name>A0A9Q8PB47_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763552.1">
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        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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    </dbReference>
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        <location>
            <begin position="30"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <name type="common">Tomato leaf mold</name>
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_07386"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12732" checksum="F5622ECE469A35D9" modified="2023-09-13" version="1">MSLLIEWIRSLPDEHRGRVQCIHLDVKPERCAGPEEAYDGAQLAQDRASSVLEYCLPRRVPNGVLSINAWTLAADGQWRMVWLPTQMPLDDMWQVFIGTDSHTDLDEKQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBT2</accession>
    <name>A0A9Q8PBT2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 6A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_09916</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
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    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
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    </dbReference>
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    <dbReference type="GeneID" id="71989794"/>
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    <dbReference type="OMA" id="NKISHEH"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
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        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 14" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="246"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO19565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="52182" checksum="8921B1FB3C74EBB8" modified="2023-09-13" version="1">MSTLEDLDDMERDGKKEENNDGDKDKKQDQNGDADMKDADGEKEEDEKKEEEDLIDYEILNSSTRDIVARRRLLENDTRIMKSEFQRLSHEKQSMVDKIKDNVEKIDNNRQLPYLVGNVVEILDLDVEKEAAEEGANIDLDATRVGKSAVIKTSTRQTIFLPLIGLVDHEKLKPGDLIGVNKDSYLILDTLPAEYDSRVKAMEVDEKPTEKYTDVGGLDKQIEELVEAVVWPMKEAERFKKIGIKAPKGALMYGPPGTGKTLLARACAAQTEATFLKLAGPQLVQMFIGDGAKLVRDCFALAKEKAPSIIFIDELDAVGTKRFDSDKSGDREVQRTMLELLNQLDGFASDERIKVLAATNRVDVLDPALLRSGRLDRKIEFPLPNEEARAQILRIHSRKMTVDEGVNWPELARSTDEFGGAQLKAVCVEAGMIALRSGQSKISHEHYVDAISEVQAKKKDTVNFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC11</accession>
    <name>A0A9Q8PC11_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764064.1">
        <property type="nucleotide sequence ID" value="XM_047909840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC11"/>
    <dbReference type="GeneID" id="71990570"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10692"/>
    <dbReference type="OMA" id="IFVWGTG"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="157"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="159"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="214"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="297"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="350"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="408"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="465"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="593" mass="62283" checksum="FEDF88CEC234F60C" modified="2023-09-13" version="1">MAQIKYIKKTKTSTETDATMAPKRATRGASEAAKPKANTKAKVTKPAPAPKTKTAASKANGTAKPAARGRATKSKKEDAAETDGETETKKPKATKGTTATKKAPAKKVAAATNGTTAPAKASRKRKADDDEAAAAPVKKVKTLTKGPILIEPPTQRLNVYVFGEGTAGELALGTAKNAVDVKRPRLNPNLSAQTVGVTQIAAGGMHAIAITHDNKILTWGVNDQGTLGRDTEWDGGLKDMDENASDSDEDEAEDNGLNPKECTPGEVDWSKTDVAEGTRFVQVAAGDSSSFVLTDDGKVYGWGTFRSNDGIFGFIEGVKVATRPVLIPALKNITDIKAGANHALAMDTKGAVFAWGSGQQNQLGRRIIERTKEKALTPTEFGLPKGPKKGISSIETGSYHSFAIAKTGEVWAWGLNNFGETGIMDNAGQDDAVIINPKVVTALNGKNITSIKGGGHHSLAATASGECLIWGRIDGSQTGIAEEDIAKLPAESVIKDEQGRPRILAAPQKVSAIQGEVTHVTTSSDHNIVLTKDGKSWSWGFSANYQTGLGTDDDVPVATMIDNTAVKEQKLNYATTGGQFSILTSPAADVKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCM0</accession>
    <name>A0A9Q8PCM0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764359.1">
        <property type="nucleotide sequence ID" value="XM_047909077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCM0"/>
    <dbReference type="GeneID" id="71989807"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09929"/>
    <dbReference type="OMA" id="HHTHAIP"/>
    <dbReference type="OrthoDB" id="10474111at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="17363" checksum="6A0B130254017BEF" modified="2023-09-13" version="1">MPVKHLRNSTISPAILPPVRSTHHTHAIPPITNAQNNGKLTYFCIHSATDARRLSRYLTLREAATSKVMITIPDSQSRSNIFEAAKLVALSACIMDVEDPVYAEKLAHAAWSVLFVPGMVFESGKEVEQVSAILDLANGILSKGIEGEVELDDGVGGNRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCQ5</accession>
    <name>A0A9Q8PCQ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764406.1">
        <property type="nucleotide sequence ID" value="XM_047909256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCQ5"/>
    <dbReference type="GeneID" id="71989986"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10108"/>
    <dbReference type="OrthoDB" id="3650858at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF1">
        <property type="entry name" value="IPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="58872" checksum="F9B85EDE88E4C175" modified="2023-09-13" version="1">MNIDAFIATVQSRLDHASDHLALMQVDPVYARRYIRLLFQGEAYKSVPRTTAWQIVDSTLTMELKSLYWWFCVREEAELVRDLQHRFKDQIDPGSPLPPKYDHALSALEVVLVNFMNIRCDMCRNQIEQRPGFSKYYRWEEIGPRKLEVTRVNPEPLPNRFFTDPLYWYLINLCAPPDGRGCIDHARLFAYLEHHLATASQEERTRVDQTVIDWFSEIAVNHQLLLTLRLSRPQNHIGFTDKLLKTEKGRVWRNKLLEAGNVHLTSARPLLLKRFYETAPPQGRRDTAWLKQYDEVSVNLATYWSAIRGPSKHFEEPDVAHFIRADLDPSHIAQVNAQRQTVLDEIESRLTIPKHVNTVQLPLATERAKLELVQTSVKTKTRPEKQTDASEIDPPTSELESMSLPDDRPTAVVRTSKRAVEVFNKMFATDVEDATQGCEWDAFVHAMRDRGFTARDSAGSAVVFELPESGRIVFHKPHPTPKIDPITLRAMRKRLHKWFGFGRESFVLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCV0</accession>
    <name>A0A9Q8PCV0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">D-xylonate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10329</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764466.1">
        <property type="nucleotide sequence ID" value="XM_047909477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCV0"/>
    <dbReference type="GeneID" id="71990207"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10329"/>
    <dbReference type="OrthoDB" id="3851628at2759"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
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    </dbReference>
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        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
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        <property type="entry name" value="IlvD/EDD_N"/>
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        <property type="entry name" value="Sugar_Degrad_Dehydratases"/>
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    </dbReference>
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        <property type="entry name" value="PRK13017.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="401"/>
        </location>
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            <begin position="413"/>
            <end position="617"/>
        </location>
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        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
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            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="640" mass="70071" checksum="8AEE6CF93A440441" modified="2023-09-13" version="1">MACESKSDAEACNGCSQPDSCTNGNIVDIEDYKTELNTLRERTKELEAKLAKHTINSGKSLRSTKWFNRTDDKAMTALYVDRYLNYGLTKEELMSNKPIIGIANSGSDLTPCNQYHTTLAHRVREGIRSAGAIAIEFPTHPIQESSRRPTATLDRNLSYLTLVELLYAYPFDGVVLMTGCDKTTPACLMAAATMNIPAICLNVRAHAQRGTVLWKAREEHAAGRIDDEELTNLVTAGTPSVGHCNTMGTASTMNALAEALGMALPGSAAIPAPYRERAQCAYRTGLQIVEMVHKDLKHSDIMTRAAFENAIVANTAIGGSTNAPIHLSAIAKHIGVPLSLDDWDSLGYHIPLMVNVQPAGSMLCEEYYRAGGLPAVMAELLEQGKLHGNAITCKGKIVAENVLGKQSWDRRTILAYDEPMKKDSGFLHIRGNLFDSAIMKTSVISKEFREEFLENPSDPNAFEGKVAVFDGPEDYNRRIETADIDPRTILVMRGTGPLGYPGAAEVVNMTAPGHLLKKGLKYSLPCIGDGRQSGTSGSPSILNASPEAAENGNLAILRDGDKLRIDLSKRRVDLLSSEEEIENRRKELLDGGGYKAIESHTPYQDFFRRETGPLSEGMVFKRAVQFQKIAQKVEMPRDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCW8</accession>
    <name>A0A9Q8PCW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764529.1">
        <property type="nucleotide sequence ID" value="XM_047909554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCW8"/>
    <dbReference type="GeneID" id="71990284"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10406"/>
    <dbReference type="OrthoDB" id="3932237at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="18175" checksum="C5407A15358D7D35" modified="2023-09-13" version="1">MADIINPVPKPRPSRYTTTFFDFLSLPAELQLQIIELMVKEPKPINIDRDLTYRSATQPAITRVCGSIRADALPLHYRLNTFEGNYCSWSWLCERTMKCLSGIGAVNHGYLKGMVLCHTFPYTKRKDCLKAVEWALRKMEAEVVEGKHERVIVTFPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCZ9</accession>
    <name>A0A9Q8PCZ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09876</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764645.1">
        <property type="nucleotide sequence ID" value="XM_047909024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCZ9"/>
    <dbReference type="GeneID" id="71989754"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09876"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF2">
        <property type="entry name" value="ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="57269" checksum="E95B67166C2DAB1C" modified="2023-09-13" version="1">MTTSSTTMDSKDRSVHSDGGAYKATRGGNANDQRDMARMGKTQVLQRNFKLVTMFGFSAILMCSWESQLSSLSIALQNGGTAGLIWTWLISWMGFTAVYASMAEMGSMAPTTGGQYHWVSEFSPRKYQKVLSYFVGWLGVLGWQALQASIAFQAGTIIQGLLVLNYPSYVYERWHGTLLVIAVLVCGALFNIFLATRLHLVEGTILVVHVYGIFCILAPLWILSPRSSSEYAWQAFQDPGWHSAGLSALIGMQASVVPLLGADASVHMSEELKDAAYTLPRSMMWATSLNGALGWVTAITVAYCIGDLESVVNTPTNYPFIQIFYNTTGSRPATNAMAAIIILMDAASAISIQASASRQIFAFARDDGTPFAAWLSRVSPRLDVPLNAVICSTTIACLLSLINIGSTVAFNSLISLTNGTLMVSYGMCIGCFVWRRLSKQPMLPSQFQLGRYGLLVNLLAMSFLSVVFVMAFFPPTPLPALTVMSMNWSSLVFTVVAVWGIVFYLVWARFRYSGPVEYVRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD54</accession>
    <name>A0A9Q8PD54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764650.1">
        <property type="nucleotide sequence ID" value="XM_047909446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD54"/>
    <dbReference type="GeneID" id="71990176"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10298"/>
    <dbReference type="OMA" id="DPNWQTH"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040219519" evidence="1">
        <location>
            <begin position="18"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="54054" checksum="2623180A9BEAEC0A" modified="2023-09-13" version="1">MKLTTFTAAALPVLASAAQYTEEQYDSGEVMAKMMEAKESAWARHRAAGHYDSKKWAGFSEGRANARRAKVECIDGKAEAVPGDADQTYKCSGIDMYDFKTHAEIGGPASEGSGSWGVVIDGREFVGIGQTEGTAFLEVLPGGSFAYLGRLPVTPGAEPVIWKEIKANGDYLIIGSEAESHGIQIFDMKKLLDIDPASPKVFDSATEVTSLFNDLPIGRSHNVVVNEEKNYAVAVGAAPRTDACASGLIFINMDDPANPYSPGCAPQDGYVHDAQCIVYRGPDEKYNGRDICYGYNEDTLTIYDVTDKEGPNASTIISKTPYVGASYTHQGWILDPNWQTHLLLDDELDEGVISPGETNPGPSDDGFPATFIFDITSLENPVNTGFYKSSVQSVDHNQFVHSGLAYQSNYQAGLRILDVSSIPDDPTGGGVEEIAFFDVFPGDDDEPGGGVATWDFGTWSHFTFPSGFVVINTIDRGPFLVKMSAFSGRGFGKRWLRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD95</accession>
    <name>A0A9Q8PD95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sterol 24-C-methyltransferase</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Delta(24)-sterol C-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_09835</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the transfer of methyl groups from S-adenosyl-methionine to the C-24 of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12 13">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764710.1">
        <property type="nucleotide sequence ID" value="XM_047908983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD95"/>
    <dbReference type="GeneID" id="71989713"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09835"/>
    <dbReference type="OMA" id="KNNAAHR"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003838">
        <property type="term" value="F:sterol 24-C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000121">
        <property type="entry name" value="Sterol 24-C-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 12 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="6 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="15">
        <location>
            <begin position="80"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO20344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="377" mass="42820" checksum="EB2A7A1C66301F62" modified="2023-09-13" version="1">MGATQLEKEDKERDAAFKEALHGKSAQRGTWSAMLSKNKDAQKAAVDEYFKHWDNKGHEDETEETRKQRRDEYATLTRHYYNLATDLYEYGWAQSFHFCRFSKGEPFRQALARHEHYLALKMNLQEGQRVLDVGCGVGGPAREIAKFSGVNIVGLNNNDYQIERATRYAEKEGLSNQLSYVKGDFMQMSFPDNSFDAVYAIEATVHAPSLEGIYSEIFRVLKPGGVFGVYEWLMTDKYNNDDLHHREIRLGIEEGDGISNMEKIEVALEAMKAAGFELEEHEDLADRPDELPWYWPLSGELKYMQSVWDLPTLVRMTHIGRGLAHRFVGGLEMIGLAPRGTQKTADSLAKAADCLVAGGKEKLFTPMYLMVGRKPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDA5</accession>
    <name>A0A9Q8PDA5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation machinery associated TMA7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764719.1">
        <property type="nucleotide sequence ID" value="XM_047909222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDA5"/>
    <dbReference type="GeneID" id="71989952"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10074"/>
    <dbReference type="OMA" id="QAKEMDT"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7239" checksum="DB8785DEC07180AE" modified="2023-09-13" version="1">MPSGQGAGTNPIHNKKPKKKPAAEEDDEDIAFKQKQAADKKAREELAKKAGGKGPLNTGGQGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDF9</accession>
    <name>A0A9Q8PDF9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylacetaldehyde reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764800.1">
        <property type="nucleotide sequence ID" value="XM_047909306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDF9"/>
    <dbReference type="GeneID" id="71990036"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10158"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="367" mass="39528" checksum="D93AFEE219980187" modified="2023-09-13" version="1">MASSQSDLVLVTGGSGFLGSHLILQLLSKGYTVRTTVRSTSRIEETRAKLSCGGATQDQIAKLEIRTLDLVTDSNEAWTKACSGAEYVLHTAGMIATGKEKQVDDLLVPMREGTLRVLRAAKAAGVPKVVFTSSIASIAHGHGKRGKSEPFTEEDWTDLTEKKEQLHIYPKAKTLQEQAVWDFIKSPEGQGLEIAVICPGAIYGPTLSKEYASSLKLIGILLGGMPGVPQYGTAMVDVRDVADLHIKVMESPKTHAQKYLAISGRADEIEPASNCVCEFVSMVRAADILRKNLPAEKTSKLPTRTLPNFVMRAAGYFDPVVGVCLPDLGKELAGSFVKARSELGWQPRSVDEALLASANSLIEFGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDN7</accession>
    <name>A0A9Q8PDN7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764863.1">
        <property type="nucleotide sequence ID" value="XM_047910547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDN7"/>
    <dbReference type="GeneID" id="71991277"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11399"/>
    <dbReference type="OrthoDB" id="5371583at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29698" checksum="4E232AB0AB4C0B13" modified="2023-09-13" version="1">MMAPYSQDNISLKPMPLSSETSLHSGLSANSYDPVPPSNTTKQDPSFSQAALEDFHLKRSIRILKLVSRLLATILSATTLAPLLQTLIKFLRTKDIYFTVEGQTRTAWAHDTIAWYTYMYAAVSAVSLLLNLVVLGAYLRGGFRGGNKAAVYESGWTWFIFGVNVVVWAVSAGIYRYGKEPVDGKFRNLWGWTCSTSAQEFQDVLTSVDFEKYCGVQTSSFYSGVANVATSVLNLVILVLSVMRCKTKRRVTVTPVQRSGDMEPLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDS4</accession>
    <name>A0A9Q8PDS4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine aspartase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764923.1">
        <property type="nucleotide sequence ID" value="XM_047909981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDS4"/>
    <dbReference type="GeneID" id="71990711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10833"/>
    <dbReference type="OMA" id="MKHRGRI"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.30:FF:000007">
        <property type="entry name" value="Similar to threonine aspartase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="442"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="627" mass="67296" checksum="9A30820FA6E0D6FC" modified="2023-09-13" version="1">MFKSSSWSKGRKGMDLSCIFVHAGAGFHSKDNENYHLQACNDACKAGMALMKTGGSATDAVEIAIKVLEDREITNAGYGSNLGFDGVVECDAIVVDHFGRSGAVGAVAQIWNPISLARTLLDHSTQSLSLRRVPPNLLVADGATKFAQEHSIPSVPYDAMISPFAKHRWQKWRMDLVKAEQSKRRAEADRSGVPPPEESADHLTGFQSERDNNESLRRVHESAMSASCYNDAQPISPPPVSSRDDGDDSSSNTGHSKSATWGTPTSHATRDTTPEDHPDQYTDPFGPPELAEQMARHPFANSTQKLSPRARLPSSFQPRGNADGGQTSPDLPMRDFGGLVMQHPFSDATSPTARARSHDGSSGYDSDNTATIDDTATVEDYFSPSTARRESTSTTTATLPHPAEDLPLPESPETTHAPFPVPSPSMFPPYPPVEEGEDVITDTVGAIAIDTYGNIACGASSGGIGMKHRGRIGPAGLIGIGAHVIPMDEDDEEKATLATVTSGTGEHMSTTMAASVCSERIFSNTKRLRGGKIVECNTEEEALRNFIQNDFMGHPSVKNSESSGAIGTLTVKKTKEGVWLYFGHNTDSFALASMHSDEAKPVCSMSRSMGNGSLAQGGRAIRYRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDT8</accession>
    <name>A0A9Q8PDT8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_11470</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764980.1">
        <property type="nucleotide sequence ID" value="XM_047910618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDT8"/>
    <dbReference type="GeneID" id="71991348"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11470"/>
    <dbReference type="OMA" id="ERLRYMD"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22881">
        <property type="entry name" value="Mdv1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000881">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="339"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="381"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="482"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="597"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="140"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="274"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO20614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="715" mass="79109" checksum="924B4941D358FBB1" modified="2023-09-13" version="1">MADSRGRSTSPAQQTRSNHRHNHSEDDSIVSSRHIEQFGRTIHATASQLIGANFANHDAPGQAEYRSALSSVRRFSQRPAIQRSVFSFARANPTELIRSHFQPSEIEHRALTYIPDEVLRNVPESSSPFSLFEGFKASLPEDEDAGKSARRKRHSRHGSKGQKAIEAAAEEQSGPPKLHKIRRERDKLEHRLEMVGIRKTMCSSEIREIDNKIANLNTMRKVILDRLAGLEDEEREIEQEVMDVGEKLEEAQEAWADEQALAQRIDPLIAAAKAEQEGQDGEAKEPKDPDSPGFMSESVYGKLPKVKESPKPKRKKQTRRISMPVLHEHMEPGSRIREIPAHNDVITAIDFDAPFGILVTAALDDTVRVWDLNAGRCMGLLEGHLSSVRCLQVDENIVATGSMDASIRLWDLNQADYNPQAPTTGTSLNNQTIPEEDAEADSMAESATGAVMFTPNSSEPEQLPLQATYQSDAMAECHMLTLQAHVAEVTALNFNGNTLVSGSADKTLRQWDLENGRCMQTLDVMWAAAQASTLNPPAKQEVSEAGGWWRPTGGRVQSAEADFIGALQVFQTALACGTADGMVRLWDLRSGMVHRSLVGHTGPVTSLQFDDVYLVTGSQDRSIRIWDLRTGNIHDAFAYDNPITSMQFDARRIVAAAGEDVVKVYDKTDGRQWDCGAGATTAEDETKPSIIERVRIKDGYMVEGRRDGVVGVWSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PER7</accession>
    <name>A0A9Q8PER7_PASFU</name>
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        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765522.1">
        <property type="nucleotide sequence ID" value="XM_047910572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PER7"/>
    <dbReference type="GeneID" id="71991302"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11424"/>
    <dbReference type="OrthoDB" id="3561261at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="98" mass="11313" checksum="00E63E454D518BC1" modified="2023-09-13" version="1">MSEPRNLILTWTGDDFKSNTPPPNVAHVCHEAREETLKQYELTFASRGRRARILFGFSKDTLYITDDALIILLPQSSGRIQRLKHFRNDNFMAQKCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PES9</accession>
    <name>A0A9Q8PES9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765537.1">
        <property type="nucleotide sequence ID" value="XM_047910246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PES9"/>
    <dbReference type="GeneID" id="71990976"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11098"/>
    <dbReference type="OrthoDB" id="3931937at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="318" mass="35071" checksum="A83C92C0310325AB" modified="2023-09-13" version="1">MADLIGNVASSITTTFKLAEFILNVQAASEEAHVFGQLIQRVRTDRAEALRERKERYETLCHQEAKQKWVNKIIADTDQALGTIGKIVENARLDGLKGRPITLQHRFEWVLKKKTDFLTKQHLLNTCHQSLLAAILYMQTLPIKPSTSSLFSPTAPPAYVEELGDETESMLQSQSARRPKKSEEYVLPDTLSFTAGDDFDPGLDLDNYTVAGPAESVAQKGAVQEHPWDQAPQSEVRGAAADAIRELGGDSQTMAAIAESLQRATSDARRRRREAIFVDDPTDSTAVSGGTSALPQDAGPRSSTLNRRRRIEAHFADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFU6</accession>
    <name>A0A9Q8PFU6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Curved DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08966</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766003.1">
        <property type="nucleotide sequence ID" value="XM_047908114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFU6"/>
    <dbReference type="GeneID" id="71988844"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08966"/>
    <dbReference type="OMA" id="SRMFYSE"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000016">
        <property type="entry name" value="Putative curved dna-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="3">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="45875" checksum="4DEEFB001F625E63" modified="2023-09-13" version="1">MAEPVVDYSLANADTLTKYKTAAQISQKVLETVSAWCTEGAKIVDICQKGDKLLEEEVAKVYKGKKIVKGIAHPCTVSPSSYVTPYTPLVSDAEEAEKSLSAGEAVKIQLGAQIDGFGSIVCDTVLVGAKDNAISGRPADLLLATHYANELLLRLIMPPGLLAQGTDEEKKKAQAVKPYSQSKITQLLEKVAKSYECTLVENTTCWLFGRNEIEDKKKIILSPSEGVKGEGLPEVGEAWGLEVGLSTGTGKVKTLSNRPTLHRRTTTTYGLKRPSSRATLSEVQKKFGTFPFSLRQLDDERAGKIGVVECVRGGVVRQYEVIGSTDGEPVSRLFTTVAVTKNGVQRLAAPPKHDISQWKSDKKITDEEILKILEQPLSKEAKSKPKNKKKKKKPAKKAAPKEEEEEDDDDDDDEDDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG81</accession>
    <name>A0A9Q8PG81_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bola-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766211.1">
        <property type="nucleotide sequence ID" value="XM_047908336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG81"/>
    <dbReference type="GeneID" id="71989066"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09188"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10998" checksum="2F371A3F0787392C" modified="2023-09-13" version="1">MSARTDAEAEQNRMSSGITPDSLGATLREKLSAVHVEIVDLSGGCGQMFEAIIVSLQFAKKTTLARHRLVNATLKEEIAAIHAWTPKCFTPEEWEKKKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI54</accession>
    <name>A0A9Q8PI54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767271.1">
        <property type="nucleotide sequence ID" value="XM_047911141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI54"/>
    <dbReference type="GeneID" id="71991871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11993"/>
    <dbReference type="OMA" id="PNWVGFL"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040250785" evidence="2">
        <location>
            <begin position="18"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="36836" checksum="F08A7EB3F0D24DA1" modified="2023-09-13" version="1">MSSLAAVLFTFCVLTAATPLAGPPGYGGGKAQSWPGWPGISHMFVFSDSYTTTGFEVNGTQPSAANPFGNPPYPGYTSSNGPNWIDFLTTTYNQSFVKTINLAYGGATIDGALIPAYLPTVLSVKQQVNDEYIPTYAGHPEFFDWRSKDTLFAIFIGINDIGNAYGWSNSLVVFDKVIAEYAGLVDKLYQTGAKNFLFLNVPPVDRSPLTIAAGKTAQSTEKKAIASWNQRVARIAQNLSSTHQDATTFVFDTNAVFTQVLDKPGSYKETSGYKNTTGYCEAYENGTPTWYTKYVNCTYAVDEYFWLNSLHPTFPMHNVTAKQIAKQLSSTQRGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PID1</accession>
    <name>A0A9Q8PID1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flap endonuclease GEN 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11672</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767379.1">
        <property type="nucleotide sequence ID" value="XM_047910820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PID1"/>
    <dbReference type="GeneID" id="71991550"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11672"/>
    <dbReference type="OMA" id="FPWHIAP"/>
    <dbReference type="OrthoDB" id="2959108at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09906">
        <property type="entry name" value="H3TH_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000037">
        <property type="entry name" value="Rad2-like endonuclease, putative (AFU_orthologue AFUA_3G13260)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041177">
        <property type="entry name" value="GEN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037316">
        <property type="entry name" value="Yen1_H3TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18380">
        <property type="entry name" value="GEN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="112"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="404"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="536"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="629"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="723"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="836"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="854"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="939" mass="103607" checksum="54B2A51BBB22C556" modified="2023-09-13" version="1">MGIHGIFKEIGPGQRVSLVKLSSDHLIAHNRPFRLAIDISIWLFQILASKGGSNPALRTFYYRLLRLLSLNIHPLFVFDGPYKPTFKRNKKVGGPGVRVASVPEFLAKQLLKQFGFPWHIAPGEAEAECALLQREGIVDAVLSEDVDTLMFGSGVTLKNWSSEGTSKVPTHVNVYRAEETKEKSGMDREGMILVALMSGGDYITEGIPGCGPKLACDAARAGFGKDLCEVARMKDKEGLNAWRERLQHQIFTNEAKYFSRKNSKLVIPDEFPNQEVLGYYTHPCISTPEKLERVRDSLQWDQSIDFAALRSFAADAFDWRCLGGAKKFIRNLAPAMLVREMRLQSDGVQVSQEAQAVREKDFIIAIHGKRIHKTTDAEVEYRMSFIPMSLVPIDLTIEDKDDDFIPAGGVEDPSDVESEFAPIPNSTADEDDAPTSPTKKRVARPYEPDQPEKIWMMHSFLELGCPLTVEDYEASLRDPKELFKARRKARAATAGDTNMHAKKTTRKKKTVDSAQLPMAAFTTVTKSSQQEVVIVSSQEDRAPLQASKTGANARAKKTKLDPRDDEDDTDDVIDKVSGFKRPSQLSPSLMKQFDPLEDDDETPKASRLADPPIDKTRIFAPFASKALAQAKAKTTTKARSKQQADPQKTPRHLKRSSDEVISPAMSQRTINSYFSPTPRKQLNFIDLISPAPVTASPPRATTPTPPRTTAQLGTDLLDLAENASWSPGKLPGSVTKRRKKAPLKRHLTAPVQGRDDDLLLPTATSRPGTPDLLDVGIGQAGTRHDTIEALDLTESSPARTTRPPKNAARADSHSMPRPSEEPPVRLSPERSSAPPATIPPLNPPASKPTKAKAKATSSRASSSRSSTNPDPVIRRSPRQQEAKKKRIQLRESLQGSWKEVDVEAVDLTEDGSGWSQSQGRTKIKGWRKSGVEVLDLTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJX1</accession>
    <name>A0A9Q8PJX1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768204.1">
        <property type="nucleotide sequence ID" value="XM_047912245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJX1"/>
    <dbReference type="GeneID" id="71992975"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13097"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21223">
        <property type="entry name" value="CH_ASPM_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="625"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1010" mass="110422" checksum="B6EF16AAF252707C" modified="2023-09-13" version="1">MSRTSLATPCPTNGLGSIASRHSISDDTTTNIEYTRAFEPSLKATKPRRSSMFPSKAAKRAPVTIFEDVAEDEDLVVAERLPNAQGKTLLSKPARKPVMTAAVAAGSGIEQRASGLMEVGQSRSRLSLAKDARIGSGQVGRVGGTEVVSGEDRVEVGGVLKKEARRRTIFMPSDDTTMLTIHPGAHASNRLEDTFQLSRTTNITQQEPMETKQKDISKPGRRPRKSLAVAPRRIPLQQSFEDLNKQIEPWDVCGDNTGKENLPPMAEKMLDLKPFVGVSRPDAARAGSRPSIYQPTAASLRRQPTVSRTAVPITAPVAPRVTSTTVSSRVTAMPPLRDTNVNRSQAAASKPRTIILGYSGRKTNVGKEEAMRRLEREVVKLCLYPVLSEDLAQPELYENSWLRQQEVALTEVVNGIFASTDALAKASSVSAMRKAFVDVYHRAEVTMLHKRLQASLLYGALSKPKTATFLRDLSRDIGLRKRFMTLWLDSYNEDALRTAAEIVVGRQVPRSSPSGSAKGISEAENVLDRLSGRRALTKFLETFFAAPVDIDASEAQFSTSAETVRWRKTMLRSLMLVWLLDEAKVTGIVTGCLYKRSAVAKSSTAVLHELSGMLMPSVGDITRALKQMDYEVHHVQDPLDEVKYHVENLAVGLRDGVLLAHLVEVLLYSNKSVKKVPDDVTITMPDTTTLTSQYWTSGVLRNNRMLSQHLKMPAIGHAQKTFNVQLALSALECHDVRAANVVGDITADDIVSGHREKSLSLLWSLVTVFGLTHLIDCKALAADVQRKAGGACNQAQLSIDEPEMLLQEWAAAYANRSEVNKVTNLTTSFADGQAYAAIIDGFSTYMPAGVTTKRSSGDGNATLEARLESLGCSKAFTTQLASTVGNIPSRETTISNLAFLASRLLPLAGIHHAAATIQRAFRQKRARTVASQRIALMRMARDCATVVQTGQRIDAAATTIQRAWRAVLDARLRKMSNDITRFQTMARGWSARRIARGSGAVAPQRVMCGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK08</accession>
    <name>A0A9Q8PK08_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768244.1">
        <property type="nucleotide sequence ID" value="XM_047911909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK08"/>
    <dbReference type="GeneID" id="71992639"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12761"/>
    <dbReference type="OMA" id="YTFLVYR"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040204529" evidence="1">
        <location>
            <begin position="17"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="138" mass="14540" checksum="D70B7D38D7CE111C" modified="2023-09-13" version="1">MKYSILASLLVSLACAAPSPVVTPVAELEKRQSSNVNVNGVGIRSASAARVRQSFTASGVVPTLIPTETFCTAPASPLEQHRYTFLVYREPAGYSPNILGAQVRLAFDLLGYTRAGGLGQPIAGNFFNQSLTNGIVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLS6</accession>
    <name>A0A9Q8PLS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769090.1">
        <property type="nucleotide sequence ID" value="XM_047913173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLS6"/>
    <dbReference type="GeneID" id="71993903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14025"/>
    <dbReference type="OMA" id="AWFLVER"/>
    <dbReference type="OrthoDB" id="5342507at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16526" checksum="81DF2ED5E54CCCF6" modified="2023-09-13" version="1">MGFFKGGILRLTSTFLYFVAFCCSMLILGATIWFVVSFRGSTRDFGIIGISAASAVYSFVAMLLTCCLAGVSFFALMAIVFDTVFMAVMMAVAVLNRAGRVGCPDNASTTCRLFVATFAVAIIGVFAYLINIGISFIMRRRGDDRRVRKTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM47</accession>
    <name>A0A9Q8PM47_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Target of rapamycin complex 1 subunit mip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_14424</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769328.1">
        <property type="nucleotide sequence ID" value="XM_047913572.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71994302"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14424"/>
    <dbReference type="OMA" id="TEVCTND"/>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="5">
        <location>
            <begin position="169"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="967"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1028"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="981"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1523" mass="170162" checksum="180CC83C49322C2F" modified="2023-09-13" version="1">MTRGAMNEVNGKHPQPVLDEAELFPRHHDKSSSFGASERLYRPATSISLKGQANGNYGEQSDSDDDDALHIHATNGHQPGKPALSRAKSDFGQGAPHPRQGRHGSEVSKEEELNMRHGWHTQLQNEEVTKNLSENFFMYYEDKRHETAGNLPPEFNPSKLVTEWRMKDRLKTVSALLAVCLNVGVDPPDVIKTNPCARLECWVDPVPPDSSNQNSNNTNAQIGKNLQSQYENLSLRTRYKVILDPTIEELKKYTTSLRRTAHNERILFHYNGHGVPKPTQSGEVWCFNRSYTQYIPISLMDLQEWLGAPGLWVWDCSAAGGVIQHFLEAAGKHSAAQTEVLKRDPNRAQSGQPLPRWEDSIHLAACRDNEVLPTNPDLPADLFTSCLTTPIMMAVRFFILQNPLSSTSTVTLAEARNIPGKVSERRTPLGELNWIFTAITDTIAWNCLDKPLFKKLFRQDLMVAALFRNFLLAQRVMRMFHCHPVSHPNIPDTHDHPLWKSWDLAVEMILSQLPKLIQQQKANEAAVEAAPSGQQPPPPIPELEYVHSDFFADQLSAFEVYLSSAPSNPGAAGYAKPPEQLPIVLQVLLSQVHRLRALVLLSKFLDLGPWAVNLALSIGIFPYVLKLLQSQALELKAPMVFIWARILAVDQTCQNDLLKDQGFAYFTNILVTTSGIPIGNVAEHRAMCTFVIAMFCKDFGQGRNACMTNNPELVDNCLQHLSDMENPLLRQFSLLCLSNLCRDFPPAREAYILQGAHERICDRSHDPVPEVRVACLNALASFIATQDIEQRDTVELEEIIVGIVCSMGMDGSIMVRKELTIFYSEYVKKYEKRFITTAWEQLLEEQDKKQGKAPNEDDFVPGSDVPGLNGGINGVKSHQRSVSANIPRSTDAAPVFIKPTMRTEYSKRTVYRAVWRQLMSLSADPHPEVARNAGVVVDYTLNALLESPLGPHAEALLDLIQLQRPVNGGPKLSVTPAAEIMSRRPSRDFGRPETPPSPASSTATKPDGYFALSRTASVAAAMKNLIGWGPKTPGDTPSTPSSPTHARRSSVYSTTGTPYRSRPLTPADAAQLPPDLLDNIPGPPHQMAAPVPPTPYYKGRDGKELPRLPLRSDFFDWSASYFREPQMRPSEADEPGSKDYNERLWRRNRNDKIIASTQPLKEAASSTRWDKPCGFFGIGAAPVKMVFHQFENHLVTSDDRDSIAVWDWHTSQQLNRFSNGNPKGSRVTEVRLINEDDVAMLMIGSSDGVIKIYRHYEDPEEIHHVSSFRALSDLFDSEKGLSSGLVFDWQQGQGRALVAGDDRVVRVWQVGQELCISDIQTRTRSCITSLTSDQVEGNVFVAGFGNGSVKVFDQRLPRSDQMLISWNEHKSWIVGAHLQRGGMRELITAESNGGIRLWDIRMRGSVDSYNPRSARSPRSLRTLSVHEHAPVFATGGRDHTIRVYSTRNISAGRSISSFEPYMSYLRGLNTPRNAPITATAFHPHRMMLACGAVNDGHVNLFKCDVPDYEKKGGVVDEWKSEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMK3</accession>
    <name>A0A9Q8PMK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769556.1">
        <property type="nucleotide sequence ID" value="XM_047913292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMK3"/>
    <dbReference type="GeneID" id="71994022"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14144"/>
    <dbReference type="OMA" id="SSWHTHI"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF274">
        <property type="entry name" value="ALPHA-CARBONIC ANHYDRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040414865" evidence="1">
        <location>
            <begin position="21"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29724" checksum="B6AE32D1B85210F8" modified="2023-09-13" version="1">MRTTTTISSIVLLLASSSLACDISHLTKRSSSTSPWSYDTPTHWADDDQANILCHDGMHQSPIALTSQSMGGPHIPLFNYEGDWAGQISNTGHGIKFVVDRPEGDNTALPSLDFDGERVYLDSFHTHVPAEHVIDGDRSTGEMHFVHVDAQGNPKAVVAFRFDPSSGSRNVTSTFFEQFGQFPALEEHGSHKRSVKGCRPSLALHEVAEYHSYWSYSGSLTTPPCSEGLRWFVARDVMVLGDEQLQALVNVSHYSARPTQRSWLHDVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMW6</accession>
    <name>A0A9Q8PMW6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMW6"/>
    <dbReference type="GeneID" id="71994045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14167"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="100" mass="11236" checksum="46EC39C045D20359" modified="2023-09-13" version="1">MTQRFVDGRPRVQLEVKQTPKSMPPEHCEATEHDAPSSSFITSPRSTAARPPALLVKSSMVSCMAGSDQRIDRPPLASLESVARAYYSPNKRRRQRQKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQB8</accession>
    <name>A0A9Q8UQB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isopenicillin N epimerase component 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763080.1">
        <property type="nucleotide sequence ID" value="XM_047906069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQB8"/>
    <dbReference type="GeneID" id="71986799"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06921"/>
    <dbReference type="OMA" id="VVIDPFR"/>
    <dbReference type="OrthoDB" id="16747at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050509">
        <property type="entry name" value="CoA-transferase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228:SF5">
        <property type="entry name" value="ALPHA-METHYLACYL-COA RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228">
        <property type="entry name" value="SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="423" mass="45979" checksum="9121A6EA3FC3F490" modified="2023-09-13" version="1">MSYCGKGVFTNRKGMFAPPLSGVRVLEFAGLAPGPYAGMLLADYGADVLRVDRAHPKAFTDDPPPPTNDALTRHKSSITVNTKTEAGIALLKHIIAKVDVVIDPFRPGVLENMGLGPEQVLLRLNPRLIVARMTGFRRDGKYKDMAGHDINYIAVSGVLGTFGREGEKPYPPANIVGDFAGGGAVCFMGIMLALYQRDTKTGMGQVVEANMVDGSAHLATMPRLAAKTPMWNGARGTNTLDGGAPYYGTYETKDGKYVAVGALEPQFYAALLKGLEINVEKDQWPNNREEKKTWKFQQEAFTKLFKQKTRADWEKIFDGTDACVTPVLEQRELEKAGFDQRPIVTLKGSPGLALAEGDADTRPPATGQGMGVQGEGWTPAGLRPGEGGEEVLGKWMGWIKGRHYKVHEGGCEALEVPRSRPRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQD6</accession>
    <name>A0A9Q8UQD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762992.1">
        <property type="nucleotide sequence ID" value="XM_047906220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQD6"/>
    <dbReference type="GeneID" id="71986950"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07072"/>
    <dbReference type="OMA" id="WPEVENK"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="68128" checksum="2BB9DF6C7BBB5FDA" modified="2023-09-13" version="1">MAGLVDHSAQQSLYVAGSMDNATSAVQHAIPAIADVEFTFLQPKVIIGFFVLLMILQARIFGVGSKKLPPGVKPLPRLPGLPYAGRFWDVPGPGIEAAWHFGDLHKKMGPIYEWKVMGIIHIWVETDKIARDLFVTRQRNYCDRNELPAAIGVKEGSEILPLMGYGEQFRRYKNFMHLIMRHANPKAFYGWPEVENKRTIRRVLESPERWSEHMIVHCARTIASVAWANPEHGSKLLTIIPTILKAVSPAGPLINKLTFLANLPEAISPWKKAEAVRRQEMTDAYMEALTDVKERVERGEEGTDCWSKLWLEKEKGTENLDFYEAAHAIGSSSFVAIATVGGPLHAFFTAMCHYPSWQEVVVEELDRVCGMRTPSVKDLPQLPKLRATVKEILRWRQATPLGVPHVAMEDDVYEGYLIPKGAILHANHYLISREETMYPNPTEFMPERFLDPAYPTYQEPLTEFPNLRNDRSFGYGNRSCPGVDLTFTELTTLIGSLMWAFEIKRPEGSSAHNNPLPWYETAPWVITMSKPFKCSIKPRSEEKRHWILEETPSGDNLIKDNKDECKTRWDVARKPGEELFAWDGLTEQAPTVHRKFGPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQR7</accession>
    <name>A0A9Q8UQR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763323.1">
        <property type="nucleotide sequence ID" value="XM_047906843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQR7"/>
    <dbReference type="GeneID" id="71987573"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07695"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="12997" checksum="39978ADF89C53533" modified="2023-09-13" version="1">MAIICEMHTRQLFKSDFEANAETAYRQHYDRIRELLNDQGRSYLEWSVEDGWPPLCEFLNKPVPHGDFPRGNEAAEFESKALDVDPARFESGRRKALSLGIVLTVLVGVVVALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQV4</accession>
    <name>A0A9Q8UQV4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="4">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_07743</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="4"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763515.1">
        <property type="nucleotide sequence ID" value="XM_047906891.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987621"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07743"/>
    <dbReference type="OMA" id="LSANWMW"/>
    <dbReference type="OrthoDB" id="6666987at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02203">
        <property type="entry name" value="PurL_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.750:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000008">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="20">
        <location>
            <begin position="37"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="19">
        <location>
            <begin position="197"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="18">
        <location>
            <begin position="466"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="21">
        <location>
            <begin position="694"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="18">
        <location>
            <begin position="885"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00052585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00057317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO19149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1361" mass="147521" checksum="EDB99F6816D9BADB" modified="2023-09-13" version="1">MSQQRAYKAFPGSSAFSDFRLARLAKAIGAKDLHAIWVHYVASQDELSAEQTETLEQLLEYGRYPDSTDELYGVLRNAVVRGSRPERGAVEVFYVVPRAGSISPWSSRATGIAEVCGLGGVVGRVERGVVFAVRFEGKGGEGDVGGVLRNADALHDRMTESIGMDPPDLGKMFAQAPPAPLQKVQLLQNPAGPRAALEEANRTLGLALDGSEMEYLIDAYTNKLQRNPTDVELFMFAQVNSEHCRHKQFNAKWTIDGVEKENSLFGMIRNTHKRHPQHVISAYSDNAAVLQGYNGSLWAPDQFAGEWKQTKEMVHYLAKVETHNHPTAVSPYPGAATGSGGEIRDEGAVGRGSKPKAGLAGFTVSDLLIPDHRQPWELDIGRPAHLASSLDIMLEAPIGSAAFNNEFGRPCTTGYFRTLSMEVPVGDGKTEVRGYHKPIMIAGGVGTVRPDNALKTDGSVDVGAHMVVIGGPAMLIGLGGGAASSVQSGEGSVDLDFASVQRGNAEVQRRAQEVINTCTSRGAESPIQFIHDVGAGGLSNALPELAHDSGHGATFELREIDNADPSLSPLQIWCCEAQERYVLAVAPDKLDAFKRICKRERCGYSIVGKAQTEKRLVLMDRDAKDGSDARPIDLPMDVLFGKPPKMHRTVESRKLVLPSFDSSLATYLPKEPATSTAVLNNAVERVLSLPSVGSKSFLITIADRTVGGLTIRDQMVGPWQTPVADVSVTATSLTPGIVTGEAMAMGEKPLLALISAAASARMSVAESLLNLAAAGIQGRLKKVSLSANWMAASSHPGEGAALYEAVEAIGMDLCPELGVSIPVGKDSMSMKTKWEDKEVTAPLSLVISAFAPVNDLSSTWTPALRRSEDVGETLLMFVDLAGGKKAMGGSALAQTFGQVGNSAPDVHDVDYIKDFFHAVEQLHESDIVLAYHDRSDGGLFTTLIEMMFAGRCGMDLMLDRIVTSGRPKDVIETLFNEELGAVFQIRKKHENVFRGVFAPMSPITIATVPKASKQELSIHYGADCIYRASRKELQQKWHHTSWAMQRLRDNPECADVEKVNLEDDKDPGLQYKLSFKPEENIMPWGSTLNTIGIRQKPRVAILREQGVNGQAEMAFAFSVAGFSPIDVHMTDILSGSFSLASCVGLAACGGFSYGDVLGAGQGWSKSVLLHEATRNEFKNFFERKDTFALGVCNGCQFLSRLTEIIPGAENWPTFERNVSEQYEARVCMVEVTNPPNQPPSVFLHGMEGSHLPIVTAHGEGRAQFSTGASSPKALIDQGLVSMRYVDNYLKPTERYPFNPNGSPMGITGVRTPDGRVLALMPHPERTILKEVASYLPAEQAQEWGEYGPWTRIFKSARRWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR07</accession>
    <name>A0A9Q8UR07_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07434</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763608.1">
        <property type="nucleotide sequence ID" value="XM_047906582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR07"/>
    <dbReference type="GeneID" id="71987312"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07434"/>
    <dbReference type="OMA" id="IDKHEIG"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="31577" checksum="4E4BC2CA3CC8E878" modified="2023-09-13" version="1">MWIPSSAGVLLLASAAEAYLVPHPTGKYNVSLTTGPLTDHTRKENNPANAGPRTLMLSIFEPAACAATVPVEYLPNKTADFQGPFLQQILNTTLNVTPLFKEARLPVCPIRNSSCRNADDFPIVLFSPGYSIPRLYYNFMASAIASEGFMVITTDHPGDSNFITYPNGDTSISNDTVQGPENILARLHPRIDDVSFLLDQLSNVTSVAELLPHRGPRPLPTDRVAMAGHSLGGIAAVLAAEQDERLRGAINWDGNMLEIPSDCGVSQPVLLMSKGFLFPSWDEMLHFRCK</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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    </dbReference>
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        </location>
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            <begin position="325"/>
            <end position="428"/>
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    </feature>
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        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
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            <end position="163"/>
        </location>
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</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <property type="match status" value="1"/>
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    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO21476.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="322" mass="35682" checksum="CF7C1E14D5734DE5" modified="2023-09-13" version="1">MSTRRKTKALGGLDYQKCKRGELDSFYTQRTGKPVPAKVKNKGDITQHLRRLDRRPGVFRLLDLPPELRINITSYALALGEETDWTSKLSMFRHVYVDLDLGSVPDRLTKENAEQLVKAANHELYSLCSFFTTSTALKTVTVEVNLRDNHIVQPNADLRDQSFLAEALWPINILPSNIRVNLTGAAAVLPQSLSSTRELQPPQPSDILRQLRAIRNIANDLERVRDALGVPVDAGLKLLQSTINTYLNLTGSITGLLHRGMMESIEQGSAVLPVAVETLLEVILGEKGKTGDQSNRAEQAKLEGHRSAVERIKGEVESLFGA</sequence>
</entry>
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    <accession>A0A9Q8UTA6</accession>
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 9"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="27872" checksum="EE0851426F4B2037" modified="2023-09-13" version="1">MTLDIGRSRILANQDIGEDFTHVYSEKIPIWIRKAQTISIDILLYHPTRDDVLATEFPHFANLFYALIASLMTGDLKTLHIDLDHLIGTRINDEDDDLPDNQLPANVILTILHPLTFLPNTVFLSTSPLHPKTGSPIFPKRTHHNGLSIDLLEFTNLKDDIRRLNARVISTGVAPGGIRVLGRIMWDIENRHEARARVMPDYKYFGKRIGKVRQMIGTPAVRRLIERAEEVEVYWGEGCCCGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUF4</accession>
    <name>A0A9Q8UUF4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767237.1">
        <property type="nucleotide sequence ID" value="XM_047911339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUF4"/>
    <dbReference type="GeneID" id="71992069"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12191"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="102" mass="11620" checksum="863DDDD3C0D55616" modified="2023-09-13" version="1">MKGVKIRRMNVIVVTDKIEKTTACTSTCTIMPEWLVIAVGAIRFEFSGSVEFELRAMHMYTHDYVGTDLKNDLMMYHNPYMIANGCEDKDCNAFTIATSQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUI0</accession>
    <name>A0A9Q8UUI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767266.1">
        <property type="nucleotide sequence ID" value="XM_047911144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUI0"/>
    <dbReference type="GeneID" id="71991874"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11996"/>
    <dbReference type="OMA" id="AFGNMFS"/>
    <dbReference type="OrthoDB" id="10265837at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053074">
        <property type="entry name" value="NPC_Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697:SF1">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="692"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="801"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="867"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="898"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1255" mass="131097" checksum="03567C7C54076021" modified="2023-09-13" version="1">MSKRGPGANFGGDEERYGGPTLTWQNTMNDEEKPMKATAAQMAKRKIAAGRKPAGARSRGNSPAFPPPGNPAPQQGSGLFGNNPQQQQQTMNFVPQTSAFTFGSQSPSPAPSFGGFGQSAPAPAADTQQNGTPSMFGGGQSVGPSFGSTFSAAPTPTQQNGFGFGTQSTQPSQQTNNTSFSGFGATQQNGVTPTSATFGSFDKPQEPAQNGTGSMFNLGGAQQETPKSNNPFASFQFNAPKPNEPAQPSIPSIGGFPSSQPQETQNKSNGLFSFGQKPHEGTDKPASNAFAGFGQKPQENGNSTAGFGQTHTETSKPNNLFAGIGQSEKPIFTMPSAYGDKEKSTLQQTPKTALFGQAQQNGEKPAESQPPKTSLFSGNFGQTSSTTSQIEQTTAKPSPAGLFGASMSTSQAEQTTSKPSTSGLFGAGTPSQAPQANGEPKGLFGASTTSFAPIKPGGSVFDTAPKTSSNLKFNFSSADPSQVYNDKEDKDADDREGDQPSGTNAFGASQQSIFNASQGQAPSSSSMFGGGAQTQSSSSLFKPNASQQDTSMTTPGTTSQKNMFAQQATTGTPGSTTAAAPAAPRSIMDRITNPMPQSDNAPETPATQKPLFAPSMTSVTPSLFQSAQPSQHSGETPKPKSLFERMDQPAPSQPKDNPSKAKNLFERSEQPAPQQPLTPAPPSAPSHAFNVPATAPAARTIPPQQARPSAVTASTAAVRNVPAAQVQKFKELNEGMLAHLRSQDITKDWTTTFDYYVKTAAEIRATQPPAPRAGTFIAPQTQQNASSTPQSNIFEAQTLRSTAPTNTFGAETPKASTSTCAFSKPPSSAPPAAKKRPHEDDDSTQPPATEKRSKPNEPQYPSLSENASSSAKLFASALDGSKKAPAPKPAQTSGFNPSTSLFSSTAKTTTTTSAPAAVKPTTGFTPSFGAAPSGGGSFLSAFGSKAKAAEDDAKKRRMDEDYDSDEETKEQWEARDREKQEAKRKEIEAAAKAGAGFMFGGTSTNKAADATAGEKAQGAGNNTWKPETPIKFGASTSGLLSTTPAVPPPKFGNGLFGATSTPAAATQEAGKLAPPSTGFSFGPKASSLNASRATTPGVTTDGEASNAGEAKDDGDEQNDPQADDMTSLLPEEREANEIVLELPHIVTKIFEKVDDDSPKPSWISKGEGKAYVLKEKLSGKTRILQKVGVNQLALNFNPMKGMKYELHPKKDTMVIGTFFDHIHSKPGKLLRFFLTADSADEAKELARVLTEGIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUP1</accession>
    <name>A0A9Q8UUP1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12436</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767535.1">
        <property type="nucleotide sequence ID" value="XM_047911584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUP1"/>
    <dbReference type="GeneID" id="71992314"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12436"/>
    <dbReference type="OMA" id="YVWEPSP"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000220">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="368" mass="39786" checksum="A982E7EE2ECDA26D" modified="2023-09-13" version="1">MAAPQVHHLFHAPISDHSFSADRQTLAVTKDNNVELYSAQGNKFQLQDELRGHDKLITGVDIAPQSGRIVTCSQDRNAYVWEPSPTGGWKPTLVLLRINRAATCVRWAPNEAKFAVGSGARIIAVCYFEEENDWWVSKHLKKPLRSTVTSVAWHPNSVLLAAGSTDGHARVLSSFVKGTDERPEASVWGERLPFNTVCGEYLNSTGGWVHSVAFSPSGDALAFTAHDSSITVVYPSAPEQPPQAVISISTQLLPFADLLWISESEIVCAGYDCEVYKFGGSVSGWQLTGSLEADAKAGSGVAKEESALNMFRSMDLKGRSGGTVDDTKLRTVHQNSINTVRPYQGGGTGQVGQISTSGVDGRVVVWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV91</accession>
    <name>A0A9Q8UV91_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">37S ribosomal protein MRP4, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768092.1">
        <property type="nucleotide sequence ID" value="XM_047912276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV91"/>
    <dbReference type="GeneID" id="71993006"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13128"/>
    <dbReference type="OMA" id="HPVAQDY"/>
    <dbReference type="OrthoDB" id="2320368at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="339"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="584" mass="63160" checksum="0E0C75B85BDD4E9A" modified="2023-09-13" version="1">MITRALRLRHGRIALPKRSTLRRTYASASVEETSDGTPTSQPAFLQGPSTAQMQLDSIPNVRSVTLNDPNHPVAQDYAFFQHQKARTGHLGTALEPHYKPHELLTNPPSPKDITLELLLASQAHIGHATSLWNPANARYIFGVRGRKKDGESPIHIISLDATAAHLRRACKIMSGVTEKGGLVLFVGTRAGQARAVVKAAEMSKGCHLFTKWIPGTITNGQQILGSCAKKVVDEFDRDVEGFEDQLGLKAAVKPDLVVCLNPLENYVLLHECGLNNIPTIGIVDTDANPTWVTYPIPANDDSLRCVQVIAGVLGRAGGEGQVKREDSAKRGFVTYNAAHGLRVPRTERPSDRAERRESSLRQRAAHAQARSQASIEEDEFEDLTGVDVKQHEEDQRLLAEAEQQMIREQGAPAEPAAYAPAESAEETSPLLEEDVDDIYSVAENMDPIDQSLTDEQFASEDLAEDLAQFGGADQLTDSPADDAANPAVPNSTTETWPDQTGATSGETSPIGQVEDVAEELGEDVAPPAPEGNPEVEIADVGQGTEYLKDTPAEKSGETEQASPAEVETESEEKEESGKDEGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVT1</accession>
    <name>A0A9Q8UVT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768677.1">
        <property type="nucleotide sequence ID" value="XM_047912529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVT1"/>
    <dbReference type="GeneID" id="71993259"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13381"/>
    <dbReference type="OMA" id="IWIGEDD"/>
    <dbReference type="OrthoDB" id="3647238at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF81">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="58"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="243" mass="27223" checksum="9B1B70BD6477A1CB" modified="2023-09-13" version="1">MASQFHYSPLSPSSREIRLVTMAPGLTETLNDDTLECALTHTSLPSASPDGLDLSIEYETVSYVWGDANRRAFIYLDRELVSVPWSSEQVLRSVRRSDRPRTIWIDAVCINQSDLVERSQQVAIMADIYRSGSQNIVYLGNHDRTLDAALSSARSLLRTEIADAIAEGRSFLDFMHDPSGQTRLSTARITVDVDQTALLDLFSNPWFSCLWVLQEAALAKRSICICGDQEFALLDICMVAKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW18</accession>
    <name>A0A9Q8UW18_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.256</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Asparagine-linked glycosylation protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_13593</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768886.1">
        <property type="nucleotide sequence ID" value="XM_047912741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW18"/>
    <dbReference type="GeneID" id="71993471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13593"/>
    <dbReference type="OrthoDB" id="4769at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106073">
        <property type="term" value="F:dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028810">
        <property type="entry name" value="Alpha1_2_glucosyltferase_Alg10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO24520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="582" mass="66194" checksum="E55EC19A6D5672F5" modified="2023-09-13" version="1">MASVWEVALAAPLNTWFAAVNKHVTEPYLDEVFHVRQAQHYCQGHWDVWDPKITTPPGLYFISYLLSPIMGCSITALRAANVICLVALCIIIRATYDARRKTNNESGPMSQILTYHSSLNIVLFPPIFFFSALYYTDIASTLSVMASYWYFLIQLSNKETTFTGTMIQVVLGIISLTFRQTNIFWVAVGPAALTAIVELDRGHRVVKDSMYRRTQGFGDTTYSVAKTSWKMDVIYDPPAKDARIEDYLRTTVSIVVCAAKAMTQPKRVARLATALAPYITLMVLFASFILWNGSVVLGDKSNHNATIHIAQMLYLWPFIAFFAWPLLLPHFILLPLIFISRLGQLAHVEPLQVFRRRDFLPRMLISFGFLILALVIVRFNTIVHPFTLADNRHYNFYIFKLLLRPWWVRYMVTPVYVVTAWACLEQRGEAPIADPSKSGETSPASGRMAAAYEQGTEKRNTESSQRILRLADGKSSAMVSFQLVCVLTAALSLCSAPLVEPRYCIIPFVIWRIHLPLYAVDVTRDMGKKGKPSWSAVLADYDFRVVIETIWFLIINAVTGYIFLYKTFEWKSEPGGLQRFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW77</accession>
    <name>A0A9Q8UW77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769125.1">
        <property type="nucleotide sequence ID" value="XM_047912930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW77"/>
    <dbReference type="GeneID" id="71993660"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13782"/>
    <dbReference type="OrthoDB" id="422736at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="565" mass="63496" checksum="5AFA2C2B9F078527" modified="2023-09-13" version="1">MLAFKHLRTPSGSHSTEPAGFARLLTTKLAKVIATAVLAICFGLLYLQWANNNSSARVEGPVPEIIEDLKATTAVPQRQGRLHLLIPATSSNSDLCKLLLSAQILGWPTPVLINYGDVENADAYVQHLAKVEGILRYLDRLEASEEYEEDLVLIVDGYDIWFQLRPDVLIKRFYETNSAANAHAVEVYGQDLVDQYDIKQTIIFGPDKLCWPVDFSRPACWAVPMSPLPEAAFGVTAGAYTNRDNNQARWLNSGTVMGMASDLTEVFRTTLDEIHTNHTTDSDQFYFSNVFGLQEYARLSLKPELLASAKEVAYDDVEDPSEGHRYEPEIQGIKTEYHIGIDYASTMFQTLAFWKPHLSWSRVIDAWTTSDKAKSVVNPFQMELPDDIKQSAAPYEALKYGLDREGHPGWDSIQLVYNVITRQIPVLLHVTGNPQEKEYRAKWWPKLWFQASAEQLRLASNKLESREISPEPIAGIHWFNAEPEDAEEIVGAGKGGAWNDRGGWMSWKQLCKNVEEDLYAVYGDDFWHPRPKNETADAEAEAESQVLTTPDGDAPAEAEMEPATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWS0</accession>
    <name>A0A9Q8UWS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-dependent monooxygenase asL4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_14262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769548.1">
        <property type="nucleotide sequence ID" value="XM_047913410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWS0"/>
    <dbReference type="GeneID" id="71994140"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14262"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF7">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040327565" evidence="4">
        <location>
            <begin position="20"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO25182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="44524" checksum="3E477AC90450078E" modified="2023-09-13" version="1">MARLRVLIVGASIAGPAAAYWLTKAGAEVTIIERFPALRSEGGQAVDIRTAGVTVMRKIPGMEAAVRAHRAPIEGIAFVDSKGQSYGTIGATGSSEQQGLVSEYEIFRGDLSRILFDLTRDHPRVKYVFGTQISALRQNEDDGTVDVTFTSTLPPSTYDLVVDCSGATSRTRALALNCGVRDHVHPAHSWAAYFSTAKDYLNASTIGHGYSIPGGLMVAVGQDGKGGNKVTLMGHGEESTRLFREAHGKGDASLNAYLRALLDGKGWICKEVTEEMTTTPDFYASEILQLKLPSLHAGRFVLVGDAGHATGPTGFGTSAALVAAYILAGEVSKSPNDIAAALEGYEQQMRPLLKEWQKVPPFVQTIMAPQTGWGIWVRNGVFMVLAKSGLVNFVQSRLAGAFGRGEDTGLVGYGWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXT6</accession>
    <name>A0A1P8YXT6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucan endo-1,3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07955</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943160">
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    </dbReference>
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        <location>
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        <location>
            <begin position="21"/>
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        <location>
            <begin position="77"/>
            <end position="439"/>
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    </feature>
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    </evidence>
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            <dbReference type="EMBL" id="AQA29331.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15584.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="455" mass="48016" checksum="6CF89F57C17D95E0" modified="2017-04-12" version="1">MHSFFTAILAATSLIGSTLAAPVVHRADDAITPVSPGGVEDLVITAENTLNATNSQPITNSTTGAKPEEDIMSIQANQRLPLALVNNMGGAVNAYVTGLDPSGKVVFVQGNGQFYYPPCDSSYTSPREVNGPIAIPLNTAQGSTVTVTLPDYISSARIWFAQGNLHFYSVWNPATNSPSQVQPSFANPQDPSAGINWGFVELTNNQGGLYANLSFVDFVGLALGMSMRAGSGATTTVRGLRPGSVSTICNALQSQQRADGQPWGNLCQAGGNGPLRVVAPNIYVSSGNGAFGNYFNSYIDQVWSRYTGNTLWLDTQNSHGKVACRVSGSTLSCNGDNRVYNKPTAGDIFGCNSGPFAIWGSDNDVHRAVVPRLCAAFNRGTFMVNGGDTQPGPHADQYYTTSPNNQYSKIVHQQEVDGRGYAFSYDDVNPSGGVDQSGTLADGNPQLLTVFVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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            <authorList>
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            <end position="280"/>
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            <end position="276"/>
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            <dbReference type="EMBL" id="UJO10961.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L544</accession>
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            <authorList>
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                <person name="Stergiopoulos I."/>
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        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="23240" checksum="9D663743DF65BE26" modified="2023-09-13" version="1">MDHSPSAGFLARYGPRSTMSGRRLREIRHVRIHLQYHYLGPESRLERDFKASRSIKDVFHPDAVIELSVAVHLPVSPESLALEGREARPLEARWILDNHELDFDVRQASVLKIRDAMDELDQYYHGTHGGDLVAAMITHAPRFLVWGAQSFMTKPFFGPALPPVMEAVREKEEREKEEREKRELEWDAQQERDREAACGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5F3</accession>
    <name>A0A9Q8L5F3_PASFU</name>
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        <submittedName>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    <comment type="similarity">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    <dbReference type="InterPro" id="IPR050364">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF6">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
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        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="378" mass="41804" checksum="50B1C756DD7E21AD" modified="2023-09-13" version="1">MLTQIAKDPTNFVDYLGRMTGSMATSIAYGFRLPSVDDPLTHEMLENSHGFFQCVAQSKLLDWYPSLRPLAGLLPRTMNPWASQALNAYAKEKATFGKAYKMGLSSALPCFALDIEAAKPDMKLLTDHAATYIAGIAFEGGADTTRYTLQGLIKAMVLYPEAQRKAQAELDNVVGADEIPSSHHLKDLKYINQTAKEAVRWMPTAINGATPHATVKEEHYRDYRIPAGATIVLAVWSANHDPKEFDDVRRFYPERQNPDTSVYESANLASPKERGQWGFGSGRRICPGMHIAHNTLMLSIARLLWAFEFGKAKDANGNIIGIDRDAMVGGLAAMPAPFQCSITPRSAERAALISKEWAKLSERSLDAKGNYKHSMFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5S2</accession>
    <name>A0A9Q8L5S2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Monothiol glutaredoxin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755702.1">
        <property type="nucleotide sequence ID" value="XM_047899378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5S2"/>
    <dbReference type="GeneID" id="71980108"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00230"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005796">
        <property type="term" value="C:Golgi lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000093">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="3">
        <location>
            <begin position="237"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="354" mass="38811" checksum="A33DA6487F3AF112" modified="2023-09-13" version="1">MTLGDIRTTPIQFIDVSVAPLVLLQPHSLHHLRPFRISSDKPPLPFLHLTSLRQPATMPSGRQFKVIGLVTLLVVLALYYVTNGEQLTHESEFYKKTVKAMEHKKTAAEKQATYVKEKETQERIERLQKEHDAATATLATSESTEAAAPVPRPQKQKPIVGDAPTSGEKSVAGRKKMQDGKIVDKKPATDNDDGVAKVGNVASKTSSASKGDSEETESEEDHEVETELNDILKKGPIIVFSKSYCPFSKKAKHILLDLYTISPKPYIVELDQHKLGSGLQDALLKSTGRRTVPNVLINGKSIGGGDDVQALHDNDKVIDTIKAMGGKRIVSVEKNQDAESGGHRETRAEVKFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5U3</accession>
    <name>A0A9Q8L5U3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755772.1">
        <property type="nucleotide sequence ID" value="XM_047900364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5U3"/>
    <dbReference type="GeneID" id="71981094"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01216"/>
    <dbReference type="OrthoDB" id="3641845at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="425" mass="46140" checksum="D904C8DC1CA6A335" modified="2023-09-13" version="1">MEASPTADLWPQRVDSMASISVSSASSSKSMRTLSAKWMPSWLSRSAASTDSSVSSRRHSSSTTKSCLSTSTASSTSTRSSAYSNSYQLHGPSPRGLSAHKETAGAFDSAANATLALASLAEGPLDLDEDSHLHDTETGIQSGIQSHGRLSTDVNPRSKSRATSTRSKAFSNPRHSPAGFAEVEMLSRDYHGYWRSSFTATIPPAAAICGTMLLTARLPAQLGSAKMTSTDPELRQQACSLQDSFDDGASPQEAMQALHGYGIEAVVIALRSSLDAAELPIVPERPAWAIYEKIAQAKNYPDKMPILWNNVSKLLHRIPSEQMVTIMFLLSVARRLQSRGVDIDGRSAAVYLLQKLWPRYVSEEASKLLMLHYDDMPLDLPLVLEAVNYRFSGRRCNLLALDASRSDTTALVESDQQGNQETYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5Z1</accession>
    <name>A0A9Q8L5Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Disulfide-bond oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755792.1">
        <property type="nucleotide sequence ID" value="XM_047900375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5Z1"/>
    <dbReference type="GeneID" id="71981105"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01227"/>
    <dbReference type="OMA" id="GHSGAEY"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000172">
        <property type="entry name" value="Glutathione S-transferase GstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="94"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="28598" checksum="A45B1B2F85BDC601" modified="2023-09-13" version="1">MSNIHLYTTQTPNGIKISITLEELGLPYEFTKIDISKNTQKEQWFLDINPNGRIPALTDTFTDGKPIRVFESGSIMQYLVERYDKDHKISFPAGTREHVEMTSWIFFMNSGVGPMQGQANHFTRYAPEHIEYGVNRYQNETRRLYGVLDTHLKDNNYEYLVDNKLTIADIAHWGWVSAAGWAGINIEEFPNLKAWEERLWSRPALQKGANVPDPYRMKELLADKDAMEKHAAASKAWIQQGMKDDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6C6</accession>
    <name>A0A9Q8L6C6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756071.1">
        <property type="nucleotide sequence ID" value="XM_047899173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6C6"/>
    <dbReference type="GeneID" id="71979903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00025"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="169"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="584" mass="63164" checksum="0ECF732F560B05BF" modified="2023-09-13" version="1">MSLEQSPNPIPYSSPVGSRASTKIGKVYPMGYRKISRVTDSITVDTEGPKRDTGCELVSIIVLKALKGVCLCWLILHILEILDFCARTARSFCPCSTFLLPHRTLHDTSRHGTVRAMFGEKKKQQEDDQLAPVPTSDMGDVEVIKPVGGQHDAVFGEINEDGPNYKDVGWAGSAILMFKTQVGLGVLGIPGAFDVLGMVPGVIIILVIAFMTTWAAWMVGKFKINHPHVYGIDDVGRMVAGRVGREFFFWAFVLHFTFLAASAMLSISIAFNSLSEHGACTAIFVVVAALIGLLFGSIQTLGKVSFIAWAGVAGILTAIFTLTIATGVQDRPAEASQTGPYVSDYKIVGAPTFAEGISAVSTIVFAFSCLPAFFACHAEMRNPKHYTRSLCTAQGAVTLVYLIIGIVVYYYCGSYVASPALGSAGQLMKKICYGIALPGLTASCMLFVHMPAKTIFMRFMRGTEHLTSNTPTHWFAWLGCTLTITVVAYIVGSGIPVFDQLLSLVGALLATVTCFQPTGLMWMYDNFKRTDRSWKWWAGCAFSLFMIIGGTFITIAGTYGAVLGIVDSESRTSPWSCADNSNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6H1</accession>
    <name>A0A9Q8L6H1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Inositol oxygenase</fullName>
            <ecNumber evidence="4 14">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 14">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00544</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13 14">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4 14"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755985.1">
        <property type="nucleotide sequence ID" value="XM_047899692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6H1"/>
    <dbReference type="GeneID" id="71980422"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00544"/>
    <dbReference type="OMA" id="RYNTKYG"/>
    <dbReference type="OrthoDB" id="5151075at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050113">
        <property type="term" value="F:inositol oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO11619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="38225" checksum="5B4E1F3764B85A07" modified="2023-09-13" version="1">MAPAMLETPNIAENFNDHKDGLALEATDDAVHEVNLLKAEMRVKNGTATQEEIDMYEKSKFDEDKDKTQFRNYEDACDRVKNFYREQHTKQTVAYNLKARSDFKFKTRAEMTIWQAMEKLNELIDESDPDTSLSQIEHAFQSAEAIRRDGKPQWFQLTGLIHDLGKLLFFYDAQGQWDVVGDTFPVGCRFSDSIIYPGSFEENPDSKDPIYSTEHGIYQPGCGMDNVMLSWGHDEYLYNICKDQSTLPDEALAMIRYHSFYPWHSAGGYRWMMNEKDEKMIGAVKAFNPYDLYSKSDGLPEKETLMAYYKNLINVYFPPGEGETEKVIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7D0</accession>
    <name>A0A9Q8L7D0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 19">Squalene synthase</fullName>
            <shortName evidence="19">SQS</shortName>
            <shortName evidence="19">SS</shortName>
            <ecNumber evidence="4 19">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_02085</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.</text>
    </comment>
    <comment type="function">
        <text evidence="18">Squalene synthase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS). Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. The presence of a gene encoding a squalene synthase supports the identification of the cluster as being responsible for SQS1 production and suggests a likely mechanism for self-resistance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 19">
            <text>2 (2E,6E)-farnesyl diphosphate + NADH + H(+) = squalene + 2 diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:32299"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 19">
            <text>2 (2E,6E)-farnesyl diphosphate + NADPH + H(+) = squalene + 2 diphosphate + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:32295"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="19">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="4 19"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756568.1">
        <property type="nucleotide sequence ID" value="XM_047901233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7D0"/>
    <dbReference type="GeneID" id="71981963"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02085"/>
    <dbReference type="OMA" id="GEACQLM"/>
    <dbReference type="OrthoDB" id="431150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055056">
        <property type="term" value="F:D-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000003">
        <property type="entry name" value="Farnesyl-diphosphate farnesyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00050857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00053206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU368088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO12202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="489" mass="55837" checksum="83361B9FAC3B115E" modified="2023-09-13" version="1">MPSVSSIAYYLVHPNELRSIIQWKTWHNPVHERDESKESADLKECFRFLQLTSRSFSAVIQELHPELLVPVCLFYLILRGLDTVEDDMSIPLHIKEPMLRDFHNHIEDESWTFDGNGPDEKDRELLVHFDVVAKEFNKIKAEYRKIIKDITTSMGNGMADYAKNADHNANGVQTIKDYELYCHYVAGLVGEGLTRLFVEAKLANPALLQRPELMESMGQFLQQTNIIRDIREDHEDKRYFWPKEVWSKYVTKFSDLFLPENREKALQCSSEMVLIALNRADECLFYMAGVKEQSVFNFVAIPQSMAIATLELCFQNEAIFDRNIKITKGSACQLMTESTQNLQLVCEVFRRFARKIHRKNKPSDPHFLDISVACGKIERFIESIFPTQTPRTLPPGADQTVAVDSEAEAQRKAEEAEAKSDVWYLMIAIFCTLGVITFLMIGAAWFFGARFDLAFAELRKGNLSPPKGKGIISSTIAAAPSAYEGHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L832</accession>
    <name>A0A9Q8L832_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar iron transporter cccA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756269.1">
        <property type="nucleotide sequence ID" value="XM_047900744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L832"/>
    <dbReference type="GeneID" id="71981474"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01596"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02435">
        <property type="entry name" value="CCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="31267" checksum="043A0F9B8F837DDE" modified="2023-09-13" version="1">MALVYLKSIILPSQKPLQVGERQRLLDVEQQPERQSSVDSGSSNRGYDDKASHSRGNSLLHCRINPRIISDATIGLSDGLTVPFALTAGLSAIGSTRLVIYAGFAELVAGAISMGLGGYLGAKGEADAYYAALQETKECVAIDTHRAREMVHSAFNRYDFSIDTLDRLTHGLSARPEQFVDFLMRFHHQLAEADFTPSRAYISGLTIALGYFLGGLVPLLPYLFFSKVWEALYCSVLVMAIALFTFGWVKTTLVGECSVWVCFRNAVQMLVLGGLAAGAAMGCVKAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L854</accession>
    <name>A0A9Q8L854_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756299.1">
        <property type="nucleotide sequence ID" value="XM_047900007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L854"/>
    <dbReference type="GeneID" id="71980737"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00859"/>
    <dbReference type="OMA" id="THKNGYH"/>
    <dbReference type="OrthoDB" id="3926908at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="23941" checksum="57CA4401F39B99B9" modified="2023-09-13" version="1">MSGAPTPPQEEQPSGAYAAYVPHDLEYSAEFEDEVMRVVLDPPPSDHAIRIIPDDSNEVAVEGVSVKASAISLQSLPAIAEDELPLPLNDPRRIFASHVPGVRLTHPGGYLEGGPGLDPDMDTFPEDFLANNASATNATSPRAAVRKDIDVAKEVLHDRMRKRQDAINHNERIERELKKMQEEHAMEMNVHRKMAEARRAKKEAKEQRRLGKDAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8A3</accession>
    <name>A0A9Q8L8A3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_00261</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="16">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757063.1">
        <property type="nucleotide sequence ID" value="XM_047899409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71980139"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00261"/>
    <dbReference type="OMA" id="YRMYVKG"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000031">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="537"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="996"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1023"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1066"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1110"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1147"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1181"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1323"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="267"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="362"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="20">
        <location>
            <begin position="1023"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1273"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1336"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1276"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1345"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1398"/>
            <end position="1407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00059328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO12697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1430" mass="155502" checksum="EA55C26C088C7E58" modified="2023-09-13" version="1">MADNNDGGPPPGQGDAEATSPSPNPARRRAPTITIDTSAVQRNSNPNMEHEVGEDSTSGLRPTNPQSTPTELQGKASFESKESRPTSPHNVSSPQQWGMPQGFLSVPTGRSRGGSDASDAETSSTSDVTYVNTRTETDAPKAFGDSSKHDNGDHPILSDEEALKPDPGTEDDFHRENNPFAFAPGHMTKLFNPKSLGAFHALGGLSGMEKGLRTDRSSGLSADEQNVQGAISFEEATAVGTPSSDKTVVEEPEMASGGEKSGKGTFDDRKRIFDENKLPERKPKSIFELMWLAYNDKVLIVLTVAAVIALSLGIYQAIAFNGVEWVEGVAIIVAITVVVMVGALNDWQKERQFAKLNKKKDARNVKVVRSGMTQEIDVQEILVGDVLLVEPGDILPVDGIFITGHGVKCDESSATGESDVLKKTAAEEVYRAMEAREPLKKMDPFMISGGKVTEGFGRMLVTAVGINSSYGKTMLSLQESNDMTPLQAKLNKLAEYIAKIGSAAALLLFVVLLIKFLAQLPNNNARPAEKGQQFMTILITAVTIVVVAVPEGLPLAVTLSLAYATKRMLKDNNLVRVLRSCETMGNATSVCSDKTGTLTQNVMTVVAGSVGTSSRFSNRAGGNVADSADNSKPDPNKDMEDDIEDVSTSEFIGTLSKDTKTLWKDSIVINSTAFETEDNGKKSFVGSKTETALLDFARDHLGMDNVPIERSNAEITQMIPFDSGRKYMAMVIKLKNGQGYRLFVKGASEIMLRHCTNIIRDPTHGTEITKLSAENKKTLEQLIDAYASRSLRTIGIIWRDFETDAWPPRGVRRIEDDKTQAVVDDICKDMNFLGIVGIQDPLRAGVPEAVKDCVTAGVFCRMVTGDNIITAKAIATECGIFTPGGVALEGPDFRKMSKTEQKAIIPKLQVLARSSPDDKKTLVKRLKEMGETVAVTGDGTNDAPALKAADVGFAMNIAGTEVAKEASDIILMDDNFASIVKALMWGRAVNDAVRKFLQFQITVNITAVLLAFISAVSNENEESVLTAVQLLWINLIMDTMAALALATDPPSRNILNRKPDPKSAPLFSVSMWKMIIGQAIYQLVVTLILYFAGSHILDYPLDDEHKQRQLQTLVFNTFTWMQIFNALNNRRLDNRFNVFEGLQHNLFFVGIFMVMIGGQVLIIFVGGWAAFQAERQTASQWGIALVLGALSLPIGVVVRLVPDELAAAVVPPFIKDYLRKRRENRIVVTDEESPFEFNQALYDIKDELAWLKKYKGGRINSLKFSLTHPKEAFMHSRSPSRSRASSSLPRTPNNEVETEEIGHSPAPPTPDSRRRGRSRSNSALAGIAMAGIVGGSIAGGWSPVTDRREGDTDSLRFARERSVSNLSREYRLDPHPGTDKKDKLVIQEDPVEAAGRQPPSQASNTTPAFGKGPFAGEPSSAQGKKDDTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAJ9</accession>
    <name>A0A9Q8LAJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Norsolorinic acid reductase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_02347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758230.1">
        <property type="nucleotide sequence ID" value="XM_047901495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAJ9"/>
    <dbReference type="GeneID" id="71982225"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02347"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="388" mass="43830" checksum="556AD78251D345D9" modified="2023-09-13" version="1">MSLFPPAKKPASLLGYHRILSPTAGVRVSPLCLGAMNFGDAWKNFLGECGKENSFAMLDFFYENGGNFIDTANNYQAEESEAWIGEWMKKRNNRDEMIIATKFTTGFRGHGDEQIKSNFQGNHAKSIRVSVERSLKKLQTEYIDLLYLHWWDYSTSIPELMNSLHALVQSGKVIYLGISDTPAWVVVKCNDYARFHGLTQFSVYQGHWSCAFRDFERDILPMVEAEGMALAPWGSLGRGQLKPADEYNDPNRDGRKMGPQNEKYARIANKLDEIAKTKNTRITSIALAYVMHKAPYVFPIVGGRKVEHLKGNIEALGIKLTQEEIDEIEDTEPFDVGFPQSFLFPGKPYRTRYTTQDMPLVITNTALEAQPKPAPIAPRQGEESLTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBA2</accession>
    <name>A0A9Q8LBA2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Factor arrest protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757964.1">
        <property type="nucleotide sequence ID" value="XM_047902854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBA2"/>
    <dbReference type="GeneID" id="71983584"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03706"/>
    <dbReference type="OrthoDB" id="18234at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="134"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="558"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="798"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1055" mass="118436" checksum="E86626E321B55469" modified="2023-09-13" version="1">MDEVENPALPAAGESSPTIRPVDEEVEPANGSEDALAVKSGIDTVEAEGIVVDGSAGEQLPATRAIPPARPPLKRDSSQPPPSQPPPAPPAQPAETGEFPQEPPDSLTLADLKRIRNSFPNAQQAPKQQLLEHEKVYDFDYQDAQSFPVEIEEWLSYSEEEDTKLRRCKAVFNDEWRATEDGKFDWLDVTEDARRSFIQTWIKVLQDKPKEQDASRALMVLTYIGLGVWEETAGRQEGCALEDLFDNSKLGGSRLDEYGSSSLQVQWIVAMVDALHSCGSLRAVYDTLRRVCDNDFQTAASDMSPRNEPQTRRTDESLELWCSLTLLYLFIEVARTTGTSATLRDDILALEPNLLNYLTQIVARLRWDEYAPVPLTKMLLLAWKTILVSFGGIKDVERVKASLTEHRDEKDTRGQPLITASPLDYHLFRQEISSKYPAYQPPPPLFALEPENNSILPPLKHRRPSYAAVNEAMFTGAPTVGTGSIMHQPVHIATPAPSPPPSPAGPGKAGKKQNYQTNQMFPFLYPPLDASSNELGGKGSTELQDALVGRRWEGSDVPTSILEAAELFAKRMRATWAMKQLWEARVDFMKQERGWENPEDESHLPEVDDFELVPTLAPEETVEQGQPVAQTDEQRRLTKVNDYYRDSLPHLQSVVIVLLKAVLQNVTDLVTKGNGQNGLQAGIQFNDTTGVNGTKPLENGVNGHSDGIENTAEELDKLRSQEITAKALSAILLLLLKWFKVSHILQYEYMTQLLLDSNYVPLILKLWQTQEIGRACHYKLDRDERNFFYFCQTNSRHGVPKSPEVHTPDAAAEESEDDAAPPPIKLKRDEPQEKPESPIADMLDFTHPPEVDELGYPQTPLPPIPLKSYSYRNIFSAINYLRVLQKITRRKTHRALLLVSYKSSNHLKKTLKIPIHPLRYYTLKLFKSQVPFCGRKWRQGNMKIITAVWLSVPAELRDDWLSGGGGGMGGACVGDVDGTVEDALPLEQSLRALTHWWNVRNFSDVMGVEKGMIEEEMDYFTRELEKMDCVVRDENMANEEHGLGDEAWQGPIEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBC8</accession>
    <name>A0A9Q8LBC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758742.1">
        <property type="nucleotide sequence ID" value="XM_047902864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBC8"/>
    <dbReference type="GeneID" id="71983594"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03716"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="16747" checksum="AE2FFFC1CD96230D" modified="2023-09-13" version="1">MSSTTTTTITPLSSTSSNPPCCTTPCTLLCTLLSQIHELEFETATEACDMLDDFTSDQLKHLYTLRDDALAQLSTQDLHISAPLVKDAYSNFVERACATPWKAQRRASEESVCSTEGGRERRDSGVGLPATPAKGRRDSGVAVAFGASRGFLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDR8</accession>
    <name>A0A9Q8LDR8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08107</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759943.1">
        <property type="nucleotide sequence ID" value="XM_047907255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDR8"/>
    <dbReference type="GeneID" id="71987985"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08107"/>
    <dbReference type="OrthoDB" id="5099852at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="65"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="16544" checksum="4F2C8D9352B940EE" modified="2023-09-13" version="1">MRRAVGCVWESIDMRGDTHRKSLCCSATAQFATSTKPRHSNYQSSLARMVQKRGPSGNSFRSIMVATAISLAGLLYGLDTEIIATTIAHDSFKRYMYGSLATNTPIQGAIVSGYYAGSAVGSAAASYCMGRMSRRWSLLFGSVVSIIGAILQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE63</accession>
    <name>A0A9Q8LE63_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760105.1">
        <property type="nucleotide sequence ID" value="XM_047903526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE63"/>
    <dbReference type="GeneID" id="71984256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04378"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="187" mass="22026" checksum="DD9CD11D8E55A268" modified="2023-09-13" version="1">MGILPLSYMALSLDTDDKPITARILVFLRTCRLVYWEAAALFYHRDHLVLSSYDLLAQDPRFPKDDVDRPGQFWTWTSPVRSVSIKHLTVSFQFSEHYIPVCRRLRVMTELKTIRFVVQYVRGDDEDRIEDELLLRALRVLAKDLRPILQNFPALSEIRYSGPNDRQQTGPHKVSREDWSVRFAEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE77</accession>
    <name>A0A9Q8LE77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General amino-acid permease GAP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04907</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760272.1">
        <property type="nucleotide sequence ID" value="XM_047904055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE77"/>
    <dbReference type="GeneID" id="71984785"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04907"/>
    <dbReference type="OMA" id="AITVGYW"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004762">
        <property type="entry name" value="Amino_acid_permease_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00913">
        <property type="entry name" value="2A0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="10">
        <location>
            <begin position="84"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO15906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="588" mass="63496" checksum="2AF33AC834CA474D" modified="2023-09-13" version="1">MEDSEKSIKADYSPRSSSTLPEYGETTVHKGTWSTRLVDSFKRDPNAHATPKSAVGADGRVFDVEGAVAATANSPLQRSLKGRHLQMIAIGGSIGTGLFVGSGSALAHGGPASLLIAFGLVGIMLYCTVHALGEMAVLFPVAGSFSAYSTRFLDPAWGFAMGWNYAMQWLVVLPLEIVAATITIEYWSGGSINNDAWVAIFLVLIIVINLLGVKGYGEAEFVFAIIKVVAIIGYIILGIILNCGGGPNGGYIGGRYWHTPGAFNNGFKGLCSVFVTAAFAFAGTELVGLAAAETENPRKSLPTAIKQVFWRILLFYIVSLTIVGLLVPYDNPQLLNGTSSADAKASPFVISITNAGISGLPSVMNVVIMIAVLSVGNSSIYGSSRTLAALADQNQAPKILGYIDRKGRPIVAIGLASVLGLLAFFAGSSFQTDAFNWMLALSGLSSIFTWGSICLSHIRFRAGWKKQGHSLNELAFRSQPGVIGSWIGLIFNCLVLVAQFWTGAWPIGYASTTAGELVENFFMAYLAAPIVILFYVFYKIWRKTPFVRSHNMDLHTGVRDLNIAELIEEERIERQSWSPWKRYYKLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEC9</accession>
    <name>A0A9Q8LEC9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoporin NUP56</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760035.1">
        <property type="nucleotide sequence ID" value="XM_047907057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEC9"/>
    <dbReference type="GeneID" id="71987787"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07909"/>
    <dbReference type="OMA" id="LFKGMRC"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF142">
        <property type="entry name" value="RAN-BINDING PROTEIN 3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="401"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="189"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="57279" checksum="BCC231F768608895" modified="2023-09-13" version="1">MAHEKEQIPLSDTEGGEERTAREHLSKTHITHDQNAPRSESASARTLAPEGNGSNGATTTGAAQSLHRKRSHEEIDADSQERSQPPRHHARKRSRDSTAEEDELNNGQRKTSGERARDGNETIEADHEHAQVNGAAKPPRATTPDRHEQKRAEDAAEAVASPKTKRSRLHSTTAEDKYVAIAQAANAEKIAESAVSDSQGDVKAEGTTKIPPTSGFANASVTSPFGSLSGSKSPIKSPASEAQTSASAFASSGFGALSGSTTSAFGAIGKESGGFGSGGSFATGAKSPLNASDNAKPLSPPSSTFGGSLAQKSAFTSTGDGGSGFGSGTSGFASPGTGGFGGGLGGTGFSTIGGGGLSSFASGKTLAPLGGATTLKPFGAGADPEEDAKAGDDGDKTGAKSPLATEKDEQHEQFYEQVMTTGEEDEVTEFTSRAKLYNFAPNPANNDKKEWRERGMGVLRLNVMKALSDDDQDQKPTARLLMRADGSHRVLLNSPIKKELTFGAPNGGKPTGGYLYFMGTIDGGLELLQLKLKQANALDLFEHIESLQKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFD0</accession>
    <name>A0A9Q8LFD0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760741.1">
        <property type="nucleotide sequence ID" value="XM_047903124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFD0"/>
    <dbReference type="GeneID" id="71983854"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03976"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="277"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="512" mass="56435" checksum="28E493CB5E69D956" modified="2023-09-13" version="1">MDLTDDMAQALMAAGRGTDIRDISLPTRTRMHVEMGDSTSDSDGDHKPTRDRKQTPDSDIPPHVPVDLKAKLIERGAKIEALAGSNYRNYNGVGWKLNSQGHKEPTTVKGRIVIDTFGFNRFNPHQAIYLTPLHARGDYTAASAPGIMPPPGMTAAMFANTIRISDGKNQIFSNPVDYDDGGMPADGFFEEEQQAKTRPPLSDEHKVLCVPLVRGYALKEKIWLNFFVNSVQDITFSEQAFEALVLPKNQKELLLGFTTTKKDSRDQFDDVIAGKGKGMIILLCGPPGVGKTLTAESVAEEMRVPLYMLAAGDLGLHSRTIEAKLEGFLEMCTRWNAILLIDEADVFLEQRNLHELERNKLVSIFLRVLEYYEGIMFLTTNRVQTLDAAFQSRIHISLEYAELDGKARRAIWNTFLDKHNSRGGSAVGGGDAVGAEKPAALAHTMSEADMRRLASLELNGRQIKNVLKVAQMLASLKGQALGYGHVDAAMEGTQYLYKASQASDQSKSSLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFI6</accession>
    <name>A0A9Q8LFI6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760635.1">
        <property type="nucleotide sequence ID" value="XM_047904389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFI6"/>
    <dbReference type="GeneID" id="71985119"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05241"/>
    <dbReference type="OrthoDB" id="4789692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="38308" checksum="6E4575475F766B15" modified="2023-09-13" version="1">MTVDDVLKRTNSSCLQGVIINPRDEHRLLLGCRSGEPDEKIAKRFVQKGTEWFHQEKVLPLRDFDQNGLRGRTSYVFEAIHTAQESNAKGAGAITKRTLNRVGPELLDKKHCGNRTYADLEAYTLCVFDQLRRFEHQSIVGVERNDAKVEEVMTRSKRKRGSDEDGEEEDVPAPKKLKPTSPVANSSGEPVADAAPLEEPSEDDQPSYILGECGQSTFESLEVGVRLDIGISTARNGHRFFVNEISREWYVDYFTFVHGNPRTKYCTAFANARNHYFFGSEDETEEPPIEDDDNHEAPEGSDSSGLSDPRDSSEASGTSSPSVAKAQRMTRSQARKMSEEGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFR1</accession>
    <name>A0A9Q8LFR1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761142.1">
        <property type="nucleotide sequence ID" value="XM_047903566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFR1"/>
    <dbReference type="GeneID" id="71984296"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04418"/>
    <dbReference type="OrthoDB" id="5772781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="36220" checksum="27300632B9C5A900" modified="2023-09-13" version="1">MDTCCPRDCDFRRWDRAVILSQGQQCASQELGKQMIEAAQPPLDSSVEAVLLRISCSWSSGRCRLDLCTPQNFMKQLADLHTRSTFPTGQFGFHMVTCVGPNAQDTTWDSSWSAFHTRLLRQFYDCELSVCGPSNDAKYEAGMEVLLTSTIPALLEPLQADGRTLNPSLVHGDLWEENCGTDFDGGQPKILDPAAFYAHNEYDFAAWRSENVPFGRPHYRQYFKHIPPSEPKEQWDDRNKLYAIRAEVHRSSLWPALCESQREIVLGYLTDLTAKYAKGDAVDGAADPRLSHAGRVHFGLTARRETSEVDMVLGCDMIFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGD5</accession>
    <name>A0A9Q8LGD5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_04554</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761268.1">
        <property type="nucleotide sequence ID" value="XM_047903702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGD5"/>
    <dbReference type="GeneID" id="71984432"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04554"/>
    <dbReference type="OMA" id="SVFIGAW"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="230"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="396"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO16902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="887" mass="95332" checksum="95125B219C547C86" modified="2023-09-13" version="1">MAASSIAERSPPYLAAIDLSECSTLAQVESVKELAYAGGLVAQVTTEDIDSALQLLKETGGRYSIYLDVSTLESQQDIVDLLDAGAAKVFVGSQQAASLKSVPTVEDHRIVYHPTASVGDATAALDGAAFGLFLQNVGSVNAVGTILQQLGKDRPPVYVSKLHITEQEAVELGKQDAVPIIPSQLLTVAAEPADGQIRIAPLLLAQTKSDRPDGLFTTLVTDERGVALGLVYSNEESVAESLRCGRGVYHSRKRGLWRKGDTSGDWQELVRIEADCDQDTLCFVVRQQGHGFCHLQTATCFGQYRGLSKLQKTLQSRKRSAPEGSYTARLFSDSNMLNAKIMEEAAELCEAQSKEDIAAEAADVLYFALTKATAAGVTLEDIERNLDAKSVKVKRRKGDAKGPYAEKFGVNGSATNGTPSKEEVREAESKPKRKEDPAGLSESGRIEMRRYVTSKESPETIQEVLKRPSQRSTDKIMNIVNPIIKDVRERGDKALLNYTHKFEKATSLTSPVLTAPFPEHLMQLSPEVIEAIDISYENIRKFHAAQKEEKPLEVETMPGVICSRFARPIESVGCYVPGGTAVLPSTALMLGVPAQVAGCKNIILASPPRADGSLTPEIVYVAHKVGAKQIVLAGGGQAVAAMAYGTESVNKVDKILGPGNQFVTAAKMIVSNDTTANVSIDMPAGPSEVLVIADKTANPAFVASDLLSQAEHGVDSQVVCIAVGLNESQLQAIDDELHAQAMALPRVDMVRGAISHSVTLVTETMEEAMRLSNDYAPEHLILQVEDPLAVRETVINAGSVFCGQWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASYVKHITSSNLTAQGLKNVGKAVMTLAGVEELEAHKRAVEIRLRYMTENGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH27</accession>
    <name>A0A9Q8LH27_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase</fullName>
            <shortName evidence="11">HMP-P synthase</shortName>
            <shortName evidence="11">Hydroxymethylpyrimidine phosphate synthase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04383</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 2 Fe(3+) + 4 H2O = L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 3-oxopropanoate + 2 Fe(2+) + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65756"/>
            <dbReference type="Rhea" id="RHEA-COMP:16892"/>
            <dbReference type="Rhea" id="RHEA-COMP:16893"/>
            <dbReference type="Rhea" id="RHEA-COMP:16894"/>
            <dbReference type="Rhea" id="RHEA-COMP:16895"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:33190"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:143915"/>
            <dbReference type="ChEBI" id="CHEBI:157692"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:65757"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the NMT1/THI5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760874.1">
        <property type="nucleotide sequence ID" value="XM_047903531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH27"/>
    <dbReference type="GeneID" id="71984261"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04383"/>
    <dbReference type="OMA" id="TKHYGMT"/>
    <dbReference type="OrthoDB" id="434407at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13650">
        <property type="entry name" value="PBP2_THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000187">
        <property type="entry name" value="4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528:SF1">
        <property type="entry name" value="4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SsuA/THI5-like" evidence="12">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO16508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="346" mass="38691" checksum="32CB58B1891637D1" modified="2023-09-13" version="1">MSTDKITFLTNWHATPYHAPLYLTQAKGFFKDEGIKVAIMEPNDPSDVTEIIGTQKVDLGFKAMIHTLAAKARNFPITSIGSLLDEPFTGVVYLKDSGITTDFRTLKGKKIGYVGEFGKIQIDELTSHYGMQPTDYEAVRCGMNVSKAIIKGEIDAGIGLENVQMVELAEWLTSVGRSKDDVQMLRIDELAELGCCCFCSILYIGNDAFIEANPEKVKSFMRAVKRATDFVLSDPEAAWAEYVDVKPVMGSELNRKIFERSFAYFSKDLRNVQRDWEKVTKYGKRLGVLDASFEPNYTNEFLEWTGEGDQADPTGDQKRMVELQKVVAEQGGFHRLDVKRAVAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI23</accession>
    <name>A0A9Q8LI23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-dependent monooxygenase terC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03924</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761369.1">
        <property type="nucleotide sequence ID" value="XM_047903072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI23"/>
    <dbReference type="GeneID" id="71983802"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03924"/>
    <dbReference type="OrthoDB" id="10016252at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="46"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15603" checksum="95E16D9BBFF7D6B6" modified="2023-09-13" version="1">MVAQMANDGLLRITYQDDGSLSREEMRERLPGKFKVIVPGSPDEDEYEVVNFSPYRIHQRCAERLRLGRFVLAADAAHLCNPYGGMGLTGGFADVGGLYDCLYGIYTGQADDAILDKYDEIRREKYWSVIDPISTGDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI62</accession>
    <name>A0A9Q8LI62_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761429.1">
        <property type="nucleotide sequence ID" value="XM_047903459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI62"/>
    <dbReference type="GeneID" id="71984189"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04311"/>
    <dbReference type="OMA" id="WENFERS"/>
    <dbReference type="OrthoDB" id="3824970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
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    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="253"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="509" mass="58093" checksum="2F572473FD4B7BA0" modified="2023-09-13" version="1">MDNSSPQHSLVSAFDLHHTVNIRYPALELLSRDDTWKMAKPRAITMRFEPNALITDPRVIENTDRNAEEGTRFLHYTKALRGHSEQYSEEEPEKHDIEALLRDMKELSRCIGSTELRAVIYRPANIKPEQRSTCMTIRRISRLKCADGLIKECGTFYVLSAPKFMDLAKTEAGLEIWYCDLRDLVLLNSDRAVRHARDTMQRYPIADEDEDVMGFATGWLPPRLPSLVPVICSKVTQAELQQEVIRDEDASECQICKQPFDHHDIVPVIVNGSCDHMYCHARLTTWVLSNGDQATCPFCRKSFTTPEQYVDLLHGTDAAGRYVYDDRFNTWENFERSCADLDTSRASLLMATPDSKITVNAKLLAEFWDYLVEQARAESETSTPAHHNPANFTELDVATTAISHGLFQIDGATLPPNALCHMLIKDIDAAFFKTFVRSEMASMVDGVVIAMALEEWARADNTMDLRPNLWLFIERTLNRMVNFVRLRRCECVGEIGLHKHGACRMYYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIA1</accession>
    <name>A0A9Q8LIA1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIA1"/>
    <dbReference type="GeneID" id="71985896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06018"/>
    <dbReference type="OMA" id="HNVIACD"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR15615">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="73"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="378" mass="42556" checksum="740C5324EF71934E" modified="2023-09-13" version="1">MAYSPPTPAQNAAALEHFIFLPVSTDMISFLAHKAAQVIRCEGQQPLNKNLPPTPPTTPPQQSAFEPALPSIEAFITTLVERSHVQVPTLMTTLVYLSRLQERLPPVAKGMKCTAHRIFLAALILSAKNLNDSSPKNKHWARYTAVRGYENFGFSLTEVNLMEKQLLSLLDWELRVTEDDLYYHFEPFLGPIRSWQQRQAEKQRMREEMAAMEQRQRAFAAEQQRRAAMEAPRYYESPRSMGQYTYQQPMYYANSSTSSSRAPSRTPSLSPPTRSRSAASTSSAESFATSSSPASVYSSNVEPIYEEPAHIQHYASHNVPCVFNVPRVLQKAPLHAHGLPLEHTDQQPAKKQKTNIFSRFLPTTLSRPAPPPIQVTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIF7</accession>
    <name>A0A9Q8LIF7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_06605</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIF7"/>
    <dbReference type="GeneID" id="71986483"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06605"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="16181" checksum="C2E96AA17EE47DCD" modified="2023-09-13" version="1">MACTPDLEALCRAASAASQRTRQLSNTGFFTKDSKKRYIVGLLDLGHRGALSRVTKQDLASPKRAAGNIMGLDLVDVLLVSDPDVAVAKKSNAGAGAGAFSMLPVMCCKGKRATLPAADPWRSASCAARAAVAVASSEVSAKRYHKLGEDASLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2D0</accession>
    <name>A0A9Q8P2D0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2D0"/>
    <dbReference type="GeneID" id="71981754"/>
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    <dbReference type="OrthoDB" id="16820at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="16437" checksum="C93A69AB12E27CFE" modified="2023-09-13" version="1">MEDGAFLARCLRAAIERRLSIAEAIQVYEIGRMPKASYKQQISYLNGWLWHLPDGAASEARDRTMRAELEGHQPIKSANLYGDPTTVLECYGYDAEAHADQEIATFANARKPARDGATTIVQSEADRIANWFLPREHQFKIKPRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2N4</accession>
    <name>A0A9Q8P2N4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TFIIF medium subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TFIIF-beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_01871</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755242.1">
        <property type="nucleotide sequence ID" value="XM_047901019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2N4"/>
    <dbReference type="GeneID" id="71981749"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01871"/>
    <dbReference type="OMA" id="ANCPEHQ"/>
    <dbReference type="OrthoDB" id="26094at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000035">
        <property type="entry name" value="General transcription factor IIF subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="12">
        <location>
            <begin position="41"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="11">
        <location>
            <begin position="258"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="336"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00081473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO10876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="41209" checksum="CEB1703D89BB42E5" modified="2023-09-13" version="1">MAEVKPEIKVDPADSPSKLGDIDEFEDDTDLTFPTQAETQRGAWLIKVSEDMWKAWNEIYQNAPDGEQIEVGKLRVYHSKPDEPQKAQIRLLTPKDDERFAPHKDLPKMYNLDVRATTYNNTIVFSEKDLPGHRAQQFGQGKNLAAGRPTGINKNDRYGGGQRKPGTYRTAIPKQITLQPPIVNEAVAKAVEDDTSLDYFKKAYDKALQGGKKTTFNATVDKTKWHPGMTNSGFTFGSTTSKPGKGQKKKKQPKEKAVRMSTNELIDALQQCFTEYQYWQMKTLRQRLRQPEAFIKEHLEGIAFLIKSGDFNGNYKLNDNTARLLNIENGVGVKEESAVLKSEPESDGGTGDEAEDDDNDEMEDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P319</accession>
    <name>A0A9Q8P319_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase lambda</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_01275</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755839.1">
        <property type="nucleotide sequence ID" value="XM_047900423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P319"/>
    <dbReference type="GeneID" id="71981153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01275"/>
    <dbReference type="OMA" id="KWHGASA"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000001">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="133"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="239"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity" evidence="17">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR622312-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO11473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="715" mass="79854" checksum="7940245E660FAFC6" modified="2023-09-13" version="1">MREEERLLRKQQMYDDLDTLQADDDAPDTGRKTSNSKWKVSKNEKPIAVERPTAARTFARSLSDSTVSAKAQNKVIPDVLLPPSSTDPLRRTQNQLASLPTLRKTVSDFPKASAASKLNGKRKRDSFILQVPEEQRVFRNLHIFFFPNNDVHPARRMRIAKAVEHGAVWEKDWSARVSHVVLDNTMDLNHLHTFLGLEQLPDRVIVVTEQYAAECLCFKTLLDPLQARFAVKGHLPAGLKKADSTDSDASLQLKPAGKDVQVRQVKTPSMERPVEAVPATIVSTAEDAEDDAEDDAEESDRVPNTSGVPVDNDLDDAIKKARELQHVPLDDEEGEDASGRPATSEGMVSGDEEPKTGLKLLPKKKSKYHRVQDKFQCMQKHTGDRSETENSAVINILQQMAVYYGQMGDEWRIRAYRNAISSLRNHPVKVTTREQALALPNIGERLATKIEEIAFTNRLRRLDNAKAEPNDQVLQTFMGVYGAGLVQASRWVSEGYTTLDGLLQKAKLTQNQRIGIEHYTDFNSRIPREEVAEHGAVVRKALQEIDPAFEVIIGGSYRRGSKDSGDIDCIITRPNTNADHLRNVVLGQVVPQLTASGFLVASLAITSRDDGSKWHGASCLHGSVVWRRLDLLLVPADELGAALIYFTGNDIFNRSLRLLASTKGMRLNQRGLYRDVIRGPKRVKLTEGTLVEGKDEKKIFEALGVTWRPPSHRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P367</accession>
    <name>A0A9Q8P367_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maintenance of ploidy protein mob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756051.1">
        <property type="nucleotide sequence ID" value="XM_047899893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P367"/>
    <dbReference type="GeneID" id="71980623"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00745"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="227" mass="25950" checksum="679562334905E252" modified="2023-09-13" version="1">MTSFMNTINSSARSRATASFQPTKRQKGTNSWQLKQFAEATLGSGSLRKVVQLPEGEDRDEWLAVNVVDFYNQINLLYGAITEFCSPQSCPEMKATDEFEYLWHDPPAFPKPTRLPAPTYISHLLTWTSNHLSNPSVFPTHPGVVFPSNFQQTIRTIFKRLYRIYAHIYCHHYGVVRGLGLEAHLNTGFKHYVLFVEEFNLADEKGNKKGEWYGPLGELVESMLRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3B4</accession>
    <name>A0A9Q8P3B4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum-Golgi intermediate compartment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755903.1">
        <property type="nucleotide sequence ID" value="XM_047900407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3B4"/>
    <dbReference type="GeneID" id="71981137"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01259"/>
    <dbReference type="OMA" id="MTNHYLR"/>
    <dbReference type="OrthoDB" id="5541786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF81">
        <property type="entry name" value="ER-DERIVED VESICLES PROTEIN ERV41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="7">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="6">
        <location>
            <begin position="183"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="44855" checksum="A5A99C3BD615900F" modified="2023-09-13" version="1">MNGFSDRGLDDSNFGESKASSVVKSFDAFPKTKPSYTQRTESGGVWTVVLIVASLFLGWSELSRWWVGETTHTFAVEQGVGHDLQINLDVVVAMQCSDLHVNVQDSSGDRILAGSALKKDATTWRQWGGRSHALAADKDERIRSGYDGKGAEYDEEDVHNYVGAARRKKKFKKTPGLPWGAQADSCRIYGSMHGNKVQGDFHITARGHGYMEFGAHLDHSTFNFSHTVNELSFGPFYPSLTNPLDNTVATTSDHFYKFQYYLSVVPTIYTTDAKTLRKIDKHHESPSSGEDGLSQYPHRYNKNTVFTNQYAVTEQSHKVPENAVPGVFIKFDIEPIGLTIAEEWSSIPALLIRLVNVVSGLLVAGGWCFQISEWAKEIYGRKGRRQDSFGMLNGEHDEKRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3G5</accession>
    <name>A0A9Q8P3G5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756140.1">
        <property type="nucleotide sequence ID" value="XM_047900041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3G5"/>
    <dbReference type="GeneID" id="71980771"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00893"/>
    <dbReference type="OMA" id="SAYIWRI"/>
    <dbReference type="OrthoDB" id="5393181at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028143">
        <property type="entry name" value="Get2/sif1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263:SF1">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08690">
        <property type="entry name" value="GET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="30015" checksum="B9A5415D4686CB97" modified="2023-09-13" version="1">MPRYSEAVRQSRLSKIKALNGGVAPPEEVVGGPAVPQKASIVDDPDEVDISQGSSFANTPSARRTPANASDDPLAAAMLRMQQEQGFLGGQEEDPMAKMMQQMMSIMGQGGGDPNDPNSKPPELPPMLANMLSGQKADDVKEPATSSAYIWRIVHAIFSFVLASYICLTSTFNGSKLARSENVYTQDAGYGLGPRLFVIFTSAELVLQSTRYFMEKGQMQSGGMLAGIVNSGMIPQPYANYIRIAGRYITIAQTVFADVMVVVFVLGCMAWWTGNATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3U8</accession>
    <name>A0A9Q8P3U8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA polymerase kappa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_00364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756664.1">
        <property type="nucleotide sequence ID" value="XM_047899512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3U8"/>
    <dbReference type="GeneID" id="71980242"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00364"/>
    <dbReference type="OMA" id="EVYTRQV"/>
    <dbReference type="OrthoDB" id="1747274at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.810:FF:000003">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000014">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000010">
        <property type="entry name" value="DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000039">
        <property type="entry name" value="Polymerase (DNA directed) kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000012">
        <property type="entry name" value="Putative DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UmuC" evidence="8">
        <location>
            <begin position="135"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="683" mass="77241" checksum="20D10A2481B1CD80" modified="2023-09-13" version="1">MTETASDSSQPSDQSTIATEPAHPATPSPALDDLPAASQSTLKYHLLGPSLTKSGQDGVDQKKVSEIIYEVSKGSKYFSNEEVKDKNLTVKINRILDKKRELQRIEAQCGLKHDMKKADDYIAELEYGRDLSQVVVHIDCDAFYAAVEELDRPELKDVPFAVGVGVLTTCNYVARKFGCRSGMAGFVADKLCPQLIHLPLNFSKYTSKAAEVRAVLEQYDPRFESASIDEAYLNLTQYCEEHSMEPEDAVSQMRAQVFQETKITISAGIAANAKLAKICSNKNKPNGQFKLPSDRASILHFMRDLPTRKVNGIGRVLERELDAIGIKTCGDIFPQRHYINPLFGEKTFEFLMGVHLGLGRTDVRPIEEFGRKSVGTESSFKDMSDPKELREKLRWTAEELEKDLQRTEFKGRTLCLKIKLHTYEVFTRQVQPPKAVYTAEDLYNFSLPMLQKLEQEFPNMKLRLMGLRCTHLVSMKKGDVDFFGRARQPQIAPSESIDVTQAAPHAELDEDGWQKWPDAEFEDAARQEREDDMAELEQLSQEYDLKHKPPQQRPPDEVTYSPDGAPSDYRRYGNGFAWRSLLEDEARTAEQNSPPRQQPEQWNCPICSTPQQADERSFNEHIDGCLSRQTIKEIVKEPTPPEQALHPLMQGSTSKRKRGRPQSNAHAGTGGDEKRPKKSFFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Y0</accession>
    <name>A0A9Q8P3Y0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756650.1">
        <property type="nucleotide sequence ID" value="XM_047901131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Y0"/>
    <dbReference type="GeneID" id="71981861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01983"/>
    <dbReference type="OrthoDB" id="3634130at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="155"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="29395" checksum="3CFDB5E8EFD3DA73" modified="2023-09-13" version="1">MATDAPSLSDGCTNEQEMSLEAQVAKLIEKHASSRDVQPPFSTGEIIVMAIVLSGLSIFNKADVLKAINAKLVESYFVAMDGGYFPNNQEWEDELVCIVPDFFETFPSYKLPLRLHSYDRDERDPVNAEYAITRSAARYYLRDLLEPKRRGTVPFTKLPAELRNIIYEMVLRFPAPGLYISHSVMSKPLKLHSIRRMDEVDVTGGPMEELSLDFAVPQEYADHYLEVNLSKTDLALLKVCRQIHHEAMPIFYGLNTFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P464</accession>
    <name>A0A9Q8P464_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757009.1">
        <property type="nucleotide sequence ID" value="XM_047899656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P464"/>
    <dbReference type="GeneID" id="71980386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00508"/>
    <dbReference type="OMA" id="TPWHPHR"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="42"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="196"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="34652" checksum="48B77A03BC27E4CF" modified="2023-09-13" version="1">MAPDTKFVGLPVIPSLNATNPKPRGIQKVFEAIEQAEGAGATVRRSIGTPRLRNFTPFLMLDHFSVAPGAGFPDHPHRGQETITYLLSGAVDHEDFAGNKGTINAGDLQFMTAGKGIVHAEMPHDDGTGSSNIGMQLWVDLPKDLKACEPRYRDLRAKEIPEATADDGKVKVKVISGRSQGVDSVQELAYTPVWLLDVTIQPGGKLAQPLPAGWNSFAYTLEGKTTWDTGATSREVPQYHNTVFEQKGDQVIASVPADAKENARFILVAGLPLDQPIVQYGPFVLTDASQVRRAMMDHGTYTNGFERAEGWASEIGKVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4G7</accession>
    <name>A0A9Q8P4G7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757088.1">
        <property type="nucleotide sequence ID" value="XM_047899533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4G7"/>
    <dbReference type="GeneID" id="71980263"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00385"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="63"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="624" mass="69874" checksum="08B0588530C90007" modified="2023-09-13" version="1">MSLTRWKSPSNSAPELLDFHYARLKSQHSIRLARIRPGSSGRVAIDLVDSYVSARGQAPSDEYDALSYTWGDLQPNKPILCNGRRLVITETLLDALKHFRLQGNAVTLWIDQICICQARPKEREHQVQPMGDIFSGARRVLVWLGGHYDDSKTGMRLAEHLLSISRDPQISHLDHHRIHNRLPASEHKGWKALASILRRPWFLTTWIVQEVVLNPNVELVLADNSLHWHELESIVGLLDGPTSRQWQLDLTMSAWELPFSRINRIRLRHQQSRLHQIKTAATDNEAVSDDPRAKADVAGFDLDLLDLLLISRDLGATDPRDKIYGLLGLSGHEMPIDYDASPEQVFNEFALAIVGSATDLAPVGVQMAKLSCKIKEVRKALTLLSCAGKPNQQRSMASWIPDWSTNLSSRPLLFDQRFCAGGDTIDIDWHFETGLHLCGKLLDTVAVAGKTSLGYTAEGNAHGLIRDWMHEARKIADTRSVRSPGSTMNVDAFQALLRDLSVCEHGYYKGDEHEAQFRRRRSMLDDINDVDTVHDARQTLTLGPTRGRVLAATTTGHICLVPRGTVVGDLIYVVLGASVPFVLRPHAEDDIAFTLIGKAYVQGITYGEWLHMDHLAGVEDVYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P512</accession>
    <name>A0A9Q8P512_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S-M checkpoint control protein rad4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757790.1">
        <property type="nucleotide sequence ID" value="XM_047902353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P512"/>
    <dbReference type="GeneID" id="71983083"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03205"/>
    <dbReference type="OMA" id="FATQWNI"/>
    <dbReference type="OrthoDB" id="251770at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18433">
        <property type="entry name" value="BRCT_Rad4_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17723">
        <property type="entry name" value="BRCT_Rad4_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="8"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="103"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="295"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="399"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="713"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="816" mass="88921" checksum="E31EC89F35C2E462" modified="2023-09-13" version="1">MAQTVDTDSQLPLKGVVLCYTSIAQDVRTKLADAASQMGAIHKLDLTSDVTHLLVGATATPKYRYVAKDRPDIKPLAPAFIDAVREVWMEGGDVDLGALEKEHMIPPFSGLQICLTGFEDMSKRKEIEETVKGNGGRYNGDLTKHVTHLIAARPEGPKYTHAKQWQINVVSLKWIEDCLVRGMALDETLYRPELPLEQQGKGAFRTKRPLDKRPREAAPVAAGEKPGRKKMRKSASMRLDSQSQDMWRDISAQEVQVDNTEMDAWNDESQSAAPVPRPASRHRPEAPAEPAAHREQNGLFSGHFILIQGFDDAKARKLKRFLEPNGATIVQSPNELEAASGVSGFQSRCLLMPHAQPIVLPGVPPGTILVTEWWVERCIHYRRHLDPQEDSLSSPLTNALVTGFASLTISTSGFGSVDLRQTAEAVKLMGATYQESLSPNTSVLVCAAENLKREKALYATKHGIPVVSADWLWASYKDKQSVSFDRFRISLEAFDAKELRTSSPAASTERSDNRSSRGSGQDAKWTDDLLQPKRLSNTRKRHAVPALQLKAPAPKSSKLKPRSGPFVYEEDEDDAVIVNNDPPAHEEQAGVQDPLSPPSDGPLREISPNASQQRSQHGGDLGRGEADKADPFVPEKKGKTAELEAPIKSPKKSPKRSPVKDGGQGLKTAQELTSNLASLLGRKDSDNPGSSGGPQKRKHRPLGRNLSGISNRSASASGSPALPAEVSESMDADGFHFSKMAPELPPSTQLGYETPEVEAHLREMSKKMGTTLLPDELSGRRVSNKATVKDSSEVVAKTSAMAAVGSRAKVRTRAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5S2</accession>
    <name>A0A9Q8P5S2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5S2"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="22012" checksum="501F4C9206F5E09A" modified="2023-09-13" version="1">MPGPPDEVEVDEPVNLPSDDYAVRKIRGIRVEPNDVEGLPPIKYEVEWQGCPEWDTSWEPIQHIIFNRQAIEEYHARADGPEVNIGRLFESELFDGAYQWCIDHDIRPRPGTEAEHPRYVELLRLRRNSALFGGATVMVSPQSVQKVGTEESQSAQKSSRSDSPAWCVNAKNHMPRNIHYGTQPSRLVTVQLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5W8</accession>
    <name>A0A9Q8P5W8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Anaphase-promoting complex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758794.1">
        <property type="nucleotide sequence ID" value="XM_047902988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5W8"/>
    <dbReference type="GeneID" id="71983718"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03840"/>
    <dbReference type="OrthoDB" id="2351920at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008401">
        <property type="entry name" value="Apc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05839">
        <property type="entry name" value="Apc13p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO14428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11991" checksum="C68B22C91F2A1B58" modified="2023-09-13" version="1">MSRDSSFTHLHLHSAHHADLLEEFTRIKLPAEHIDVPPHHQPLNPDDEDDVVPNQHAAFGIQRAQNKGREPAWKDLGLEKLMSEGPPRKGAQATAGAAGGSKVGGSRTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Y0</accession>
    <name>A0A9Q8P5Y0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the turnover of nuclear polyadenylated (pA+) RNA.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758603.1">
        <property type="nucleotide sequence ID" value="XM_047901733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5Y0"/>
    <dbReference type="GeneID" id="71982463"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02585"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000647">
        <property type="entry name" value="CCCH zinc finger and RRM domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="308"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="379"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="643"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="666"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="684" mass="76283" checksum="673F30E43684E575" modified="2023-09-13" version="1">MLHDRVADMFFDENDSELLKTWIIEKGLKDVSDADSDVLADYVIALVKTDEPEPVAKANCVENLRDFLGDRSEAVVDHVFTAIATKAYDPSKPQVQDPEPGLNQSRKRHYNDWNQDEPQTSYHNQTFDRPTKQARRGGRGGRQQHGGAPAWQHPSQPQGFPQMPALPPGMPQLDMSDPLGSLMAMSQAMGLPLPNMSGFTGLAQNGNGFGGAPAKRCRDYDNKGYCSRGAQCPYEHGDNALVVPGHEEYDPVLSIVQPTRTGVVDTSAGARGRGGNRGRGRGRGTSGRGGANRADFSHQGPVHDRSMTTIVVEQIPEDKFDEQTVRDFFNQFGDIDEVTMQPYKRLAIVRYRDHDQAQTAYDSPKSVFDNTFVKVHWYKPDSLPRPPNGHAASPAPQRNGGDVEMQEEEPQIDLEELARKQEDAQRRHEEQKKQREQAEQQRNDLAAKQKAVEEEKRRLAEMLAKRTKKTPQTEANGASPPDNKNDAAALLKRLEEEAKGLGIDPEAAYNESANPAYPYRGRGGFRGRYRGRGGYRGRGGYNPGFRGGWHGARGGAVKRLDNRPKSVLVVFTDGTFDEHEEALRQWILFNGSETHDLSKHPTRSDAVVVSCTERYIAENFMAMASMPDFQLAGKVELSWYKPEATESTPSEEMKVDVPTSDNAPVPDERTDMREDFDTADDDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M6</accession>
    <name>A0A9Q8P6M6_PASFU</name>
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        <submittedName>
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        <name evidence="4" type="ORF">CLAFUR5_07875</name>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M6"/>
    <dbReference type="GeneID" id="71987753"/>
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        <property type="component" value="Chromosome 3"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="371" mass="39648" checksum="C5F5427C10143C3D" modified="2023-09-13" version="1">MAILQRRLAMRPRIAVTLGDPAGVGPELVAKLLRDRTNLTKANIVVLADRSEVGLASKQAGDTVVPISETASQAGVQILDDNSAPTTSIPLQQATEAGGERCIRQLKRALDLWRAGEIDGVGFAPLNKTSLKKAGMTEEDELRWFAKQLGYTDTTSEINIAGPLWTARVTSHVGIEEVATMVTQESSLKAIELLHRLRWESGIEHPRLAVCALNPHNGENGNFGRQEIDAIAPAVQEAQSKGIDVKGPFPCDTIFLKRADFDGIVTKYHDQGQIALELLSFEGGVTVQGGLPIIISTPAHGTAFDIVGKNVASVVSMQKAFDVAVTMASRRLAKQDQPDTGVSYAASLSAKALDLEKSLPHVSAVEVASCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Z1</accession>
    <name>A0A9Q8P6Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UPF0382 membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
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    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="123" mass="12605" checksum="C03370996F1425A5" modified="2023-09-13" version="1">MASPWFTTAALFGGSSVAFGAFGAHGLKSRGIAPEKIASWGTAAHYQLIHTVALLVIEQAAPKNVYAKSLFAAGMVGFSGSIYALVLNPELKFLGPVTPLGGVCLIGGWLALAFGSRGRAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P722</accession>
    <name>A0A9Q8P722_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987682"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="39222" checksum="E45A7701C67BC2F3" modified="2023-09-13" version="1">MPPDPDIEKQTSRSSKSNDVEAAKEYTTVPSKYRNSLLAAVAYLDLANALDFPANVWNQVPTPLYAKVLMGIGGSIAILSTSFAFWDMVLAWRNITFLRTERRGLKQMQEKRTPTVLEQAWMGVNTRELGWEVIDRMMLNAFMAIAGILVGTGCLMAIRGDIPSVFLGSNIMSGYLGNSFVALYAVINTVWCIFMWKRAHACEGAVKRAGREIGVKMMIALKSHSRRHKIYAIVNGVSILASGIGSEISSTMWPGYEVESLDVRQRLSEIMEIREALVLDSAASIDCCEPSSGVNISDDSKTIGLMHDLGLELDRAQRADVLAFGYEERFLLELYGYFLLAREQQVATVNGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7E3</accession>
    <name>A0A9Q8P7E3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hps1-dma1 cluster O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760178.1">
        <property type="nucleotide sequence ID" value="XM_047903380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7E3"/>
    <dbReference type="GeneID" id="71984110"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04232"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF15">
        <property type="entry name" value="MONODICTYPHENONE CLUSTER TRANSCRIPTIONAL COACTIVATOR MDPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="239"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="458" mass="50831" checksum="5CD41EA408044594" modified="2023-09-13" version="1">MDDRATQGKYKACQTRAVVWTSFRPSARLFKGVSYAAIETIRRNTSALQAVVDKTNSSHAVFANYLKDHPENQPTFDSNGPLELANAPTHVNDARHALASAARDLQLLALYPTEGVNYLGLEGTGKLSLQFIGHFGVPDHVPLEGMISYDDLAKKISKVPQQRLTRMIHHAMQSHFFQEPKPSYVAHTALSAGLVKSKAMRSCLEFLMQTSIPMMPTIIQATEKYGQDAEKPENAAMSIHLKDGDSFSGFMDFMKASLEGTTIEQIVNGYDWKGLGAGTVVDVGGALGHLGIAIAESFPALQVIIQDIPTAIALGRQQLPSHLYSRVSFMPHDFYLANPVKSASIYFFSRVIHDWPDESATKILRAVVESMGPESKIVIADKVMPEQPVGGWDERMVRDYDLIMMALNGKERTSGEWRELVEKTDERLWISNVVRPEGALGSLIEVSWRRENSPMLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7I1</accession>
    <name>A0A9Q8P7I1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetyltransferase 9-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760536.1">
        <property type="nucleotide sequence ID" value="XM_047903849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7I1"/>
    <dbReference type="GeneID" id="71984579"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04701"/>
    <dbReference type="OMA" id="WHVPRYH"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="27530" checksum="ECF0DDBB26AB9463" modified="2023-09-13" version="1">MKLNAHTALSTPTLLLVPYSEHHVPHYHEWMKDPDLQSATASEPLSLEEEYAMQRSWRGDRDKLTFIICQPLRQKDDREQRPGMSHVRVGEDDSPERMIGDINLFLFDAEIEEGEREVEELGGSGSGSVVGEVELMIARKSLQRQGFGRAALLTFIDYIHTHWPDIAAEYAQSGAITPQLSFLRVKINQTNVGSIRLFEGVGFIRTTEEPNYFGELELRFVPDLEGLRKQKGWEEVVELGYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7T0</accession>
    <name>A0A9Q8P7T0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760805.1">
        <property type="nucleotide sequence ID" value="XM_047903141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7T0"/>
    <dbReference type="GeneID" id="71983871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03993"/>
    <dbReference type="OMA" id="CNILQQV"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="63640" checksum="D6AD67D770A8EE88" modified="2023-09-13" version="1">MAMYERRSSMEAFERASRTQSPSGSERRKLSFNPLGEWTPEVVHHDPPVGAFEVSKGKRIAQVAIASVYCLFAAGVVFGFAAIKPVLIEEGVYKDKCTKHELEDNVYVCYEQELRLNLMFAIAAVSTNVCALPVGTVLDRYGPRVASIIGCVFLFVGALLLAFAAQIPGDAYIPGYLFLALGGPFVFISSFQLSNTFPKHSGLILALLTGAFDTSSAVFLVYRLIYQGTSGSFTIRKFFLLYLIVPAFILVMQIFIMPAKSYKSVGELVKQAEDDAQDVHDSDEDIQDEVQRRGLQNARREHRESVVSEISELLGSKKADQHVQQEEEKVKKSGVWGAMHGKTATQQILSPWWVLITIFTMVQMLRINYFVATIRTQYTDMLGSVHKAKQVNEFFDVALPLGGVIAVPFIGLVLDHTSTPFVLVLLVSVATAIGIFGVIPEMWASYMNIILFVIYRPFYYTAVSDYSAKVFGFVTFGKVYGLIICVAGLFNFAQAGLDALTHKAFHNNPIPTNIILLTVAFVVGIALVGYVWRKSITLQEDKIKEEADEAREVLMPGANGTQVNRPHGHETYGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7U5</accession>
    <name>A0A9Q8P7U5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar-sorting protein SNF7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar protein-sorting-associated protein 32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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            <end position="125"/>
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            <dbReference type="EMBL" id="UJO16754.1"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="129" mass="14145" checksum="4FC74C8B7EE46804" modified="2023-09-13" version="1">MANYASQIPAILLAFEHLLGGQARITDKLTPSLYKRAVTNKGPGTAKALYPIIPVKDPVRHSNVVGVLMCLTGALLAWPKTRGTFAPLALNTFLTGAGIYSQRQMRIPFWLPCVNMILGGLVWWIENRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8J6</accession>
    <name>A0A9Q8P8J6_PASFU</name>
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        <submittedName>
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    <organism evidence="11 12">
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
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    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3" id="KW-0813">Transport</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="76"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="605"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
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        <location>
            <begin position="635"/>
            <end position="646"/>
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        </source>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="663" mass="72617" checksum="56CB1215B5173D97" modified="2023-09-13" version="1">MRTYGTVPVQEEADDGSGVERAATLVSSGKHERDNRTITPPLDDDARSVMSERSHESAQAGVKRLEAISSTWSKTGLYVAYVGIALLAYATSLEGQTTTNLTIFATSAFKSHSLVSTVLVIQGVVLSIVKPPMSKIADVFGRFEAFGLSVLLYIVGFIQQAASNNVETYAAAQIFYAAGQTGLQILIQIFIADTSDLINRALCSTIPDTPFLLNVWLGPALAETMLNKLNWRWGYGIWAVILPIAFLPLALALVINQRRAAMRGILPTTPFAEESWWEMIKTLWFELDLFGLLLICVAFTLILIPLTLGAKTGWDNPSLITMLVVGAACLVAIPFWERSKTLAPRAFFPRSFWKNRTLMAGLALSFFYFMAFYLSVYPYFQSYLLVVQDLPLTQAGRIVQTFTFTSTITAIIISFVIKYTKRYKIYMVIGTVVYVIGLGLMIIYRTEESTPRTIIATQVFLGIGGSLTHVPAQLGVQASASHSEVAAATALFLTFLEIGGAVGSGISGAIWTSNVPKKLAMYLPEETKDQAAEIFGNITLASRGWPMGSPTRIAINLAYQEAMTNILTVSIFVALPCIVLSLLMTNYKLDEIDQGVKGVVIGGTQDGVDNREEPIAGPSTSRLSRESTRLMAISAEEEDDEEDGENEERQDSRSRLLGSRKRS</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
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            <begin position="1"/>
            <end position="28"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="UJO16981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="88" mass="9967" checksum="908F909801FBFC3E" modified="2023-09-13" version="1">MGNERAVERDIERTLQEKSRRKGDRPSLKQEFIGGRGQEHIPGNRDLISQTNAQKVAYRDRYSHPQPALNGQSEEVSSARSKSKVCVC</sequence>
</entry>
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    <accession>A0A9Q8P8S7</accession>
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        </location>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Samaras A."/>
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            <end position="54"/>
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    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="UJO17446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="246" mass="27720" checksum="4BC74CBCAA610F4B" modified="2023-09-13" version="1">MLPHRCSRNILPTTFPQMSASNLQSFLSTLHVEGDDCGEKNNLQRRDVETKDQTDSTCKIPPRPSTPIDQIDCDDSEREGHDYGLQQSHMSLPRKLTLDDDFWSQASSAQTRRAEMAMQNGAYHPPPQMRNNIEDERAEEAEAYVLRRMIINASAINQPPPADRDTAWTTLPEGKPAGRAVPALGKSGKHEPERRKRERSLSPICCRKRRPIPANQSRAAPELAESGQHDPKPYDSILSRSSVYRP</sequence>
</entry>
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    <accession>A0A9Q8P919</accession>
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            <authorList>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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    <dbReference type="GeneID" id="71985949"/>
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    <dbReference type="OMA" id="THNQEIP"/>
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        <property type="component" value="Chromosome 5"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="UJO17491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="434" mass="48108" checksum="7B3D2DDD72E7601B" modified="2023-09-13" version="1">MPEFVYGSGPPQPVPPMKPEHISDGITLVRPLSRKGIGPGMIVLSPNEESATPIEIQDGIPSLRMKWAEEGYCVVEIRPQASSSALKTAIQRLSECHECEPKDRMGLICYGAEMWSKSATATESLKDRIVCAALYAEAAQFSTLSAQASVPTIYHLAGDETKKSLKPGSKVYEYGTNQQYSFPIPCHKDFHYATEAVSHSRNLAFLKPLMGGPYFDLELLWEEHTYYEFGDRSVANTMTTMVEEPYVNHVPTMTGGIGRKALTDFYTNHFIFSNPADTELELISRTVGIDRVVDEFIYKFTHDMTPDWLFPGLPPTNKYVEIPMMAVVNIRGDRLYHEHITWDQGTALRQIGVLPETLVLKVDAKDAGTNENNVTNGANGTNGRVNGNGVKGGVVRYEVSLPVAGTDTVAKMRDKNSVDSNKMFEFKPRELGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9J3</accession>
    <name>A0A9Q8P9J3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762589.1">
        <property type="nucleotide sequence ID" value="XM_047905173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9J3"/>
    <dbReference type="GeneID" id="71985903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06025"/>
    <dbReference type="OMA" id="RWEDPLP"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="39027" checksum="E5D14A1A392A6225" modified="2023-09-13" version="1">MGQTERPDGERLCDYISRTTMRQLTMETSLEDHLHKCHQQDQSPLFGQLPKEIRDLIFSFATDQYEDMQNKYSETAFHYRPGNRGPLTTSTSLLSTCRRIWLETSQLPIRKSKITMWFEDNRGPPASDQPKYEFSRAWTSLNKRNFNSIHVFAQKHELDRMFHGRRLNWAHQQIIPRVLRVTMRHTDWNRWEDPLPLDSSHFWLQRALYNHDLSTIDTFHLELETLETYKDQLQVIIDRLMDIHGAPRPLDPVTALIRSAEPYFWHWDGPPTINEEIYPAHAGMARLQYRVAVMTWRAKRSEPGTVPPPATAQHGGRRRPLDPQWITGPPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Q5</accession>
    <name>A0A9Q8P9Q5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate-dependent dioxygenase oryG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762668.1">
        <property type="nucleotide sequence ID" value="XM_047904794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Q5"/>
    <dbReference type="GeneID" id="71985524"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05646"/>
    <dbReference type="OMA" id="SKWHADI"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="48"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="382" mass="42438" checksum="BD9712BC0CD15F36" modified="2023-09-13" version="1">MASIAQTLEDASANIILNAKNGISNGNGHEPTRTPLKPTGILDNHEHFDLTPVIGREFPEANLVEWLQSPNADELLTELAYLISSRGVVYFRKQDNLTNNLQKQLIQRLGELSGKPSSSTLHIHPVLNSEGEIDETRDPDAQISTISSKLFKKVYSTPAATGRSSKKQSSDQWHSDIAFEPVPADYTSLRLTQLPKTGGDTLWASGYEIYDRISTPVQKFLETLTAHFARPDFTAAAVRGGFTIYSKARGSPENVGDSLSADHPVVRTNPVTGWKSVYPVGQHAQYIKDVTAEESDMFLGWFKTLLKDNHDLQCRFKWKNVNDIAIWDNHSTFHNATFDFEGLGDRAGNRAVGIGERPFFDPSSKSRREALEGSEIGTYFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA18</accession>
    <name>A0A9Q8PA18_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07277</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763029.1">
        <property type="nucleotide sequence ID" value="XM_047906425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA18"/>
    <dbReference type="GeneID" id="71987155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07277"/>
    <dbReference type="OMA" id="VNPNMAD"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="187" mass="19393" checksum="1DD96267F8BA2B8A" modified="2023-09-13" version="1">MSFPGMGPPGADRPGASLEEQQQQQMIKLMQTTMESCPAKTVMSGGMGFALGGVFGLFMASMRYDTPLGQGLPGGVGASSANMTKIPMREQLRMGFKDMGRSSYSSAKNFGYIGAIFAGSECVIEGFRAKNDLANGVAAGCFTGAFLAKSAGPQAMAFGCAGFAAFSAAIDAYMKMPSEDRAADPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA48</accession>
    <name>A0A9Q8PA48_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="UJO18694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906575.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987305"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07427"/>
    <dbReference type="OMA" id="LQMIRMN"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
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    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF4">
        <property type="entry name" value="HYPOTHETICAL AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="69"/>
            <end position="92"/>
        </location>
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        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
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        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
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        <location>
            <begin position="433"/>
            <end position="450"/>
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            <begin position="484"/>
            <end position="503"/>
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        <location>
            <begin position="523"/>
            <end position="546"/>
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    </feature>
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        <location>
            <begin position="1"/>
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            <end position="316"/>
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        <location>
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            <end position="575"/>
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        <location>
            <begin position="12"/>
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        <location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18694.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="62971" checksum="DF2D8B20725E4F20" modified="2023-09-13" version="1">MSLLQRVTSIDGEDRRPPEVDAKQLGYGTAKSLRRVISYDAIPKPAEDSQATAPTGGVTPYKVPTAQRLAQIVVTVISCWFASGIVFGFAALKPVLVDNGVYRDLCTADELNAGVEICYEQDLRLNLIFAIASTTSNVSALPVGTLLDRYGPRFAAIIGAVCLAIGAVLMASAFAIPEFDGYIAGNIFLSLGGSFLFVQSFQVANAFPRYAGTIVALVTGAFDASAAVFLFFRLAYESTGGAFGPEKFFYGYLIVPAVITIAQVTIMNKDGYKTVPQLEQKLEKMEDATRDVHDSDDDLSDGEVRRQRERRREHRESNLAKLDELLGDAEEREAREKRTREHHAASHVWGALHGKSPKEQMLSPWFILITLLTVLQMLRMNFFIATIRSQYEYMLGSIDAGRAVNAFFDVALPIGGVAATPFIGLLLDNVSTAMMLTVLVVLITAVGVLGSLPFFWAAYANVVLFVLLRPLYYSAMSDYAAKVFGFANFGRVYGTIVCFSGLINLSQPLIDAANHEVFHDNPIPINVVLTSLGLAIGVALTAFVWIQDHKIHKQEEKTGVPSERTRLLPEIDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="29726" checksum="1C91E76F0DC8BD58" modified="2023-09-13" version="1">MSPGLCSVCHSPATRPVLIRMCCKKTHTHWHEQKCYERCVHRAGNLLQAAFLRFREIGFDQKIKKVQKVDDILHITEDEYQTDMRTATEGPLFPFPDHLVQDSEDKAKVLTYNACCDALGYVFEFSQALLDGIAKNLEEIDFNLKREHLKTRRYTCSGYAKVSTVYSVLVMLAFCGEDCVVDLAGAQFGQQRAIVPFQQYTDTYLDPNKNHTVRPLPRGSNAEAIRAIRDGEKDHEFDDQYEFRVHEIHHKLDVALLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBL3</accession>
    <name>A0A9Q8PBL3_PASFU</name>
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        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="207" mass="22811" checksum="8F72DA434BBF2CC1" modified="2023-09-13" version="1">MAPQDTKAPFLRIPWIRRIITKPGTIYRIPGSRSPKSTTEDSLFAEILKTPRTIRSAISFYTRPTSEDSEIEQVTTVMTLGDGMNGHPEIIHGGILATMIDESMGILQSVNLERAHMRRVKLGQAEGELPPPGGAAFTAELTVRYLRPVRTPGAVAVVARRERKEGRKEWLVAEVRQQVGHGEDDDGEVVVCATGTSLFIEPRGVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBP0</accession>
    <name>A0A9Q8PBP0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-oxoglutarate-dependent dioxygenase gloC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763886.1">
        <property type="nucleotide sequence ID" value="XM_047905803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBP0"/>
    <dbReference type="GeneID" id="71986533"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06655"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="256"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="46034" checksum="24DC13BEDC3958EF" modified="2023-09-13" version="1">MRGCTHGLSVQYQVAADGVQVTSPHLTSTGGTLQHSILQHDLKVRTSNQRKTLHTTQTTTPTTSFSIMGSIDQATPPSSTIPIIDFAAWSNSSDACERFKISKALITAFQTVGFVYLINHGLPQPLLDQAFATSKRLFDLPLEQKMLAPQPDGPEVHRGYSHPGLEKVSQYTGGDVTKGEELRNVLDYKESYEIGSEENASQPNIRLPGSVLPDFRPLTTNFYWACNDMAQEILRCIGLGLGLEDAEYLIRYHSGHNNQPRLLHYPPVPAGDVEQGKVARMPAHSDWGSITMLFQDDCGGLEVEDAVMEGRFVSATPIRGACVVNVGDLLMRWSNDVLKSTLHRVTLPPLSDRYDGAQRMTRARYSIPYFVSADPESLVECLPGCTDAECPAKYEPVTQREYGIMRAKVQYRSAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCE1</accession>
    <name>A0A9Q8PCE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764254.1">
        <property type="nucleotide sequence ID" value="XM_047909701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCE1"/>
    <dbReference type="GeneID" id="71990431"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10553"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="518" mass="57907" checksum="AB19C67064147E0F" modified="2023-09-13" version="1">MSLEQLLSHFDNLQLQNAPTHTHVVELVCPACNLLPDRDTVPCLDPPKYAAYMSRPPKNPASLGLIDTSFHAIVSSSIASGLLAEDGAHGELLKGIEDLVYVAGRSKLAIVPFFDRNSRRFITRFQLETITKDGQTSTRTFDLGLENMEMLFDAVKSNGCISMVRHLLSRESLRAYYHVRGQLSDWHGYSFVRDEEASWDVEWASSHKTDVEHVFLEKLSRLPCDAACGMESVRYILPCGHELSTTHAAIAAMSEDDCASACCQICGTRFLTGAEVLPYEVRLASKRCKRAARIHDHWTKLDRSPSPVKYGFDGKTLLDAIRAALRGFATFELISPASQSVPRHGSIAAIMEYLERILAEEGSIREEMPETMVVLLIDDILKRVRCNYGQPLIETSLPPGCGQFFRDWMLRAVNFVTDRKCDPPACRPGIHRHDRELVYGCTAGGVVDDGRMPLTRSIDEGQKPTGMEDLQAELAEMDLERTSSLHKELAEMEVEQRPKIVGRLGREEYMMEDVGAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCL4</accession>
    <name>A0A9Q8PCL4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764321.1">
        <property type="nucleotide sequence ID" value="XM_047909113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCL4"/>
    <dbReference type="GeneID" id="71989843"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09965"/>
    <dbReference type="OrthoDB" id="3643498at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="30475" checksum="E62614F1BB73C6E0" modified="2023-09-13" version="1">MASASSESALASVINTAELLENILLHLPPADVVRSRQVHSIWKEAIAASPVLRQHIFLDPKPLKELIFFDGEPGSFSSGSCRLSHNLKDLSEGGHRVISLHPALEKIDAVGLSCFDSTHKSVSFSLDLRRLYKSAPGEWRHMSATNPLVPRVIVAVGGEPVYIVSTREGVTMGDLFDKVMELDDGLLRYSTRIWGEVPQCVSDDSGWVIQARKAARAEKYDSSRTSENAPSAVSLQGGGEWEAFGVEEFGVDEFEADEFGSFDLEDDGYYDEYTEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD16</accession>
    <name>A0A9Q8PD16_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_10186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764543.1">
        <property type="nucleotide sequence ID" value="XM_047909334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD16"/>
    <dbReference type="GeneID" id="71990064"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10186"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14499" checksum="4D761E74A7AC74CC" modified="2023-09-13" version="1">MAQYSVGKRHSVAHPVYQKPGLAVVVGEHEWYELYIFGHEIEDHDFCDAFVREIIQGIVKPPKDGKGWLPNVEVATLVCQRTKKGCVLRGLPVDCMLEIAPAYWFDEVVGGKGAGYQGSAHELCRSQEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD44</accession>
    <name>A0A9Q8PD44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD44"/>
    <dbReference type="GeneID" id="71990293"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10415"/>
    <dbReference type="OMA" id="NSRAKWA"/>
    <dbReference type="OrthoDB" id="5153521at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="195" mass="20914" checksum="A91C58351663AB18" modified="2023-09-13" version="1">MSAEQSFSQADLRATQQDYKRDATRKHKWALGPTPGVGRAEGKPRPLRSAATAYNQKRREEKGAAIASLAHGAKVSRKHDMLEGAAITDDSSAASSSERDTPSPPPADAEITYSYDASRGPTKGSQILNAALAKAVDAFQEKETVKLVKSEYELLDADGETMKATPKKGKKSKAKASASQEAVVTPDADEDYEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE31</accession>
    <name>A0A9Q8PE31_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765126.1">
        <property type="nucleotide sequence ID" value="XM_047910232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE31"/>
    <dbReference type="GeneID" id="71990962"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11084"/>
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    </evidence>
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        <location>
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        <location>
            <begin position="1"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        <location>
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        </location>
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        </source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="639" mass="70620" checksum="2114699A5C2AF108" modified="2023-09-13" version="1">MAPSRPSLSITLPSNFEFHYSDGQMPKTPEAQQQAEQSAAEPPSPPRPQPFKVKRKRVSSVPFQEPNIMLDNTVIPTIEMSEVPSDMSSPTLQPTSAHLLSPMPISAGLPRALTPPKTPAPRTYSSWQLESPAEEWDLINNTKPAFERAGSVCSSFSDSSISSCGSSAFSAPTGCYDSPDSETADPFVDDGLPKQNANLQTPVRSSPKSKRVKTRRDIKWTPQMDDHLWMTFMSYLSDPRLTPFKMLPGSTPPMGVCEKVATEARRTWRSRKIAPSEPGFADGFVELDTPQREGSPDTIRPSMFQNMQQKWPRSTAATRKRLRTLCAGRPSISAHYQRMLRTRSPSPFETSDPASQAAEPESSFSGIDMVMSLVTSTAPSMQPNGMLAQLARDEPSEPRQYRAARPDGWFDRMPRSKAHQKSASLQSELKLSLEDLSHPGADTLASPFDADSRSHRSHLLQSMSNTKSLGRAEFNGRSLEAPVEFKMGAPTDRRSRKRRFRSDEEKPRRLPLEDVFGPPVQERVARNRGFSVGAVRASDNLARLFTPATPHVTDFDQVMGEASTGAQEDVPMGCRSAPRRLAEPVPRLGSPFVEGPPLSRQHNTFPRSTLLPTGDNQDPFHQRLIELAAAHANNATNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG32</accession>
    <name>A0A9Q8PG32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766206.1">
        <property type="nucleotide sequence ID" value="XM_047908608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG32"/>
    <dbReference type="GeneID" id="71989338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09460"/>
    <dbReference type="OrthoDB" id="4525788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="490" mass="55442" checksum="4402EFAF6EDBF866" modified="2023-09-13" version="1">MPGNFHEVPESILASWPKANFDDPVRRGWMPAFALTWQVAATILLAARFYLRARRQAGEFGLDDLMIFIGWFFSLGFTTTAYIGTERYDLDRHTWDVHPQFYVGAALTQQTGWTAQLMFIFSTVPTKLSVLLFYRRMIKDSLDKRWLYAIYFAIFVTAAYGSAVFLTYCNMCHPLSAYWLSYDFTYDTEFACINGHALTVTSGVLSCLSDAYAVALPCLILRQYSLDVPKRQKIALNLIFAMGFLVTGAGIGRTYYLWRINHTYDTSWAGFDLFAWSVVECHLAIICACAPSLRAFFRHYLRDHIKRTFTSFSSVSYYAQDKPGDTEASRSTSTRALDPHEARHEDLEACISDKGRPESSMYDLNTSYPSSGALADGNSHDDITKITSPEEYEMYITAKQKKLHPHASLNRLQAVDTNLAEETVTPKSVKRASTASIEAFARSELKTIDVPSRRTSKHSGVKPRVEPAQTTFHIYSEPVVEPRGHNDNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGU3</accession>
    <name>A0A9Q8PGU3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ecp19-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766513.1">
        <property type="nucleotide sequence ID" value="XM_047908587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGU3"/>
    <dbReference type="GeneID" id="71989317"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09439"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040373431" evidence="1">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12584" checksum="1C011B04FEFC8460" modified="2023-09-13" version="1">MPLQAPFFLAFATTIMANGLVKRQGPDINEDDIPSQCQNNLDCSYFLDHVRSCDPINPPFSKDHAFQDCICLDVAALDYLSGCLQCTHQYKNGGDIRTIYDICSTYSSSFESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHP6</accession>
    <name>A0A9Q8PHP6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">eRF1/Pelota-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12091</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RutC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic release factor 1 family. Pelota subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767082.1">
        <property type="nucleotide sequence ID" value="XM_047911239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHP6"/>
    <dbReference type="GeneID" id="71991969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12091"/>
    <dbReference type="OrthoDB" id="10249111at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990533">
        <property type="term" value="C:Dom34-Hbs1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070651">
        <property type="term" value="P:nonfunctional rRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070966">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, no-go decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071025">
        <property type="term" value="P:RNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000001">
        <property type="entry name" value="L-PSP family endoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000004">
        <property type="entry name" value="Protein DOM34 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.870:FF:000001">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000008">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.870">
        <property type="entry name" value="Pelota, domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038069">
        <property type="entry name" value="Pelota/DOM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058547">
        <property type="entry name" value="Pelota_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004405">
        <property type="entry name" value="TF_pelota"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00111">
        <property type="entry name" value="pelota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853">
        <property type="entry name" value="PELOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853:SF0">
        <property type="entry name" value="PROTEIN PELOTA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26356">
        <property type="entry name" value="Pelota_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159065">
        <property type="entry name" value="Dom34/Pelota N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="60495" checksum="5E13E3299FBD3488" modified="2023-09-13" version="1">MKLIKSNIERKTGAGSATLLPEEPEDMWHAYNLIRPTDILRASAIRKVISESATSRSSERVQMTLTIRVTKLDFDPQAGQLHVSGQVAEENKFVKLGGFHTLDLELHRNFALQKADGWDSIALDTLKEAINQEAKAQLWAVVMQEGLANICLITEHQSILRQRVEVNLPKKRSGSSDHDKAVQRFYQTTFESLQRQIDLADPKPLLLASPGFTASSFQQFIKTQASTGTNKPLQQLVPKITVAHSASGHLHSLSEVLNSPAVTSKLSDTKFARETQLMERFFEMMRQDDARAWYGPKECQLAIERGAVGKGGGILLISNALFRSQDINTRRRWVKVVDDVKEQGGEVRVLSSMHESGKRLEGLGGIAAILTYPIEELDEEIPEDGGEDLPDDEMNDDAPSAILSIRTPFLQYNTTPPQQTRTMTEIKLISTPKAAQPVAPYSQAVQAGSHIFVSGQIPADAQGNLVEGTIAEKTTVCCEGMKNILEAAGSSLARVVKVTVFLTSMDNFAEMNSVYEKYFGATKPARSCVAVHQLPKGVPVELECIALSGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIN6</accession>
    <name>A0A9Q8PIN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767488.1">
        <property type="nucleotide sequence ID" value="XM_047911232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIN6"/>
    <dbReference type="GeneID" id="71991962"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12084"/>
    <dbReference type="OrthoDB" id="3939615at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="671"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="721" mass="79004" checksum="6995B805CF157F7C" modified="2023-09-13" version="1">MNATPAGQWSNYATYAILRICCERRGLQVLPVEVTNQIHDINNSRPDRQQLPTITHAGAPPVPIGSRGDPYKPPPGDTFTKKLPIEIRKQILTAWLPAKDVAVKPLCSSDPPLSKDAKRKAKRNKTSDMMTVCKKIKDEMVTCCYEERTFAIHVHEGLNTGGVEAFDAGRQPLQYHSNSHVDDRFPRFGDEDEFGFKKLKKIEITFFPTAEDTHFTTINTYYMCKALAGLLERSGGKEDRIVSIMFKFAKGQSTTDNSDRRSIIARETRWWDSDNDKPRSTALGHMSDIELVLRPFSIFDNIHNVDVELPPGADSHPDTMQFVLTLINRMTGSTLLGDSSDTFGIHDHAEAYMECKREQLQTEIFEQKHGNKANRVPDISEKEFTEDDGLEDDNSLEDDEELPSRPARKVRGTSENRWPMPQLGNSLHGDSDEEGLMMSAYSGWDSWKPRTATTRLPIKRKRRVVSEGGRHLGSSTGSTTLRDAGRLPLFGFGMNEITSLPALDGSASEGNAWQSIPPSYFMGAVASASTTPNAATNRPRKLRGERPAQSRQPPSAGMSVERAQGVATTMDEQLAAMNQFRKDTGVGTELARGWLKSAGWSLTEALARHKAEQALSSNLSTHSRGSTSSVEGAPSRYCDDAQAEQASSEDTVMADAASAMPEDAVLHQPRPGSSSSQEAASAAGPSQAVRTVEAADGKDSMEGIESVGGALDEGSTPNMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK16</accession>
    <name>A0A9Q8PK16_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768440.1">
        <property type="nucleotide sequence ID" value="XM_047912496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK16"/>
    <dbReference type="GeneID" id="71993226"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13348"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="80" mass="9164" checksum="C1570D77D8A1D6AE" modified="2023-09-13" version="1">MTIICHLGYVCAVFSPKTGQPPFKMADITADKDRIKRVADINNSTIAPETAWQYVYEPRENDDDHEDPTRNVDKELPRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK76</accession>
    <name>A0A9Q8PK76_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12884</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).</text>
            <dbReference type="EC" id="3.4.21.92"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768381.1">
        <property type="nucleotide sequence ID" value="XM_047912032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK76"/>
    <dbReference type="GeneID" id="71992762"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12884"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000001">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009205">
        <property type="entry name" value="PRK12553.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="28851" checksum="82E8400C9892AED7" modified="2023-09-13" version="1">MHFNHTRPSMEHIARSSLRATRSHVLRQAARRQTRCMSSFPPFATQSATPPRPPTSALPMPFVTETVGGGWHTSDIFSRLLKERIICLNGEVDETTSASIVAQLLFLEAENPSKPISLYINSPGGSVTAGLAIYDTMQYIQSPITTICLGQAASMGSLLLCGGEKGQRYCLPHSRIMVHQVSGGYSGQASDIAIHAKEILRVREQLNEIYRRHLTVERSLEEIGRVMERDFFMGAEEAREWGIVDKVLDRRAQVDEGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKA3</accession>
    <name>A0A9Q8PKA3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lactose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12546</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768367.1">
        <property type="nucleotide sequence ID" value="XM_047911694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKA3"/>
    <dbReference type="GeneID" id="71992424"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12546"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF79">
        <property type="entry name" value="LACTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="68"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO24001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="58583" checksum="699CDF7F1F03B9B7" modified="2023-09-13" version="1">MEPVTKSSLAGQSKEGATFISHIEDTTGDAKQIPEVVNVQGNPDFIQATTNGAPLNLLSKESLQLYLILLTACLNATASGFDGSIFGSINAMNQYQAYFRKEETGSSTGIIFAIYTIGSMVGAVFTGFVCDVFGRRAGMGIGAVIIMIGAVLIRGRFVLGLGISLGTSAAPTYAIELAPLQWRGRITGYYNTFFYSGSILATGVTYATTKDTSQLSWRLPLGLQCVPPVFILLGSFSIPESPRWLCSRGKHEEAARILAKYHGAGDMRHPMVQLELREFEESIAVQKMRSWWDWRDLVKTHNACWRIAMVALMSYGSQLSGNSVLTYYLPTMYTQLGVASTDRRLLLTFANSIVSCTGAVFGSATNDKIGRRTKLWVGSFVLAILFAAVTGFSSYFEHSRAPTSHAKSLSNAGIAFIFLFGCAYSFVYTPLTPTYCAETLDNHTRATGMGIHVIMNNTANFYNTYITAVAFKAIAWKYYLVFVCLNVVYGFAWYFCGMETKGRTMEQLQEVFDAPWPPKASLQKTRSRGLQCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL19</accession>
    <name>A0A9Q8PL19_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS-type efflux pump MFS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_14018</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768743.1">
        <property type="nucleotide sequence ID" value="XM_047913166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL19"/>
    <dbReference type="GeneID" id="71993896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14018"/>
    <dbReference type="OrthoDB" id="3940175at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="29692" checksum="375932DA70D9000E" modified="2023-09-13" version="1">MTFCFILALQWGGTQYDWADYLCVEHKAGETAMVPLTMHRSRSVSSASLGTFCNFAALRAVSFYVIRGASTLGSGLMCLPTAVSMSFFALFGGPVTTYIGYYSPVLLLGTSLSAIGTGLLTTLHPHSSAGRWIGFQVTYGMGIEMSFQPPFLAVQTVLEGAKIPMALVLLSFTQTFGGIIVLSVAQNVFPSRLAGDLVASVPQVDPNIVLQHGAIGLIDVVPMRYRDLVLTAYNSAIVDVFYITLGLSCLSVLFALGIEWKSVKNGESTEGTTSKIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLN8</accession>
    <name>A0A9Q8PLN8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769265.1">
        <property type="nucleotide sequence ID" value="XM_047913323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLN8"/>
    <dbReference type="GeneID" id="71994053"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14175"/>
    <dbReference type="OMA" id="LYFIQRD"/>
    <dbReference type="OrthoDB" id="9995306at2759"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="28829" checksum="B8989770F0205C37" modified="2023-09-13" version="1">MATRTPPSALEPYLQLPPETSLILLTGTLGCNANWLTSRMISSTLSPPNNDESTEKPISVLLISWLRDLPFWKNELRRTTGLDISKLPKGHFTFLDLFTTPPPEPHLTNLILSTITTLKTTFPASKILLVLDGPDILLATGTLTSQNLNTLLLQLRSQVHATILSCSADLPLLAAATGSTESRPTPIEVESAAVLTTQAHNARTVMSVRELETGAAKDVSGVLRVTKGGDAEGYDGESEGGDGVKEAELLYLVQRDGNVKVFSRGSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM88</accession>
    <name>A0A9Q8PM88_PASFU</name>
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            <fullName evidence="1">F-box domain-containing protein</fullName>
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        <name evidence="2" type="ORF">CLAFUR5_14219</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="5279008at2759"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="73"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="481" mass="54308" checksum="890523DFAB574C99" modified="2023-09-13" version="1">MGLMYFLKAFITGAFLGTIGAVICAFWKNWDIGQSTQSIARRLERDSIAAHDPIPAFIRTRSSRPRQGNSAGAATLSSLPPELLENVAQHLSSIDICVLRLASRDMAFKVLQTTFTREHFAKRSCLMFSLSGLETVLEIARHPILGRALRELVFYVDTVSPPEGSGRVGEYLLRSYHQRQRGVFEDQGKLVAQFDTLSEVFQQLQRYDQLRKIVIMSVRNTAQRYRYDRHKVEPPNAEVALHRLEFALMMLPGKGFTSLSALAMEGDMVCIRTPEYFNTRTTPLFSIQYLRTPFVGTALFENLASLTMTLQTDQSDYEIGMRHLLLALSRNTALTHLDLYFMPHGFEKKTPFSDSWSATMLMAASFRKLKILQVRCFKTCLSNLRSFVRRNSTLEKIILVEYASIGLRVAEYDAWETSIHGGGHALTMIKNEIGSTIDQGIGARQSKKLRETIAFTIGSYSSRNMSSQQVIASDCTTRMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMJ7</accession>
    <name>A0A9Q8PMJ7_PASFU</name>
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        <name evidence="4" type="ORF">CLAFUR5_14559</name>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71994437"/>
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        <property type="component" value="Chromosome 13"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
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        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="43"/>
            <end position="294"/>
        </location>
    </feature>
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        <location>
            <begin position="18"/>
            <end position="39"/>
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        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="36714" checksum="B06BF474A7668D24" modified="2023-09-13" version="1">MLFKTRRSVPPFRTAIHTPQRHTTSRSITMASTNGRSTPAEGRKLKILMLHGYTQSGRLFEIKTKALKKSLEKHFPAAPKPGHLQQYPGGIDLVYPTAPMKLEYSDIPGHDTDGPSDNLEACGWWKRRGDDEPYTYEGMEVGLEAIAKVLKEGGPFDGALGFSQGGAAAGMVAALLEDGRREAFEKHQAKGGMQYPDPFTNDSGYVEDAIHPPLKFAVSYSGFGASTHPLYHGFYEPKIRTPMLHFIGTVDTVVSEERSLRLVEACVDGKGKEGGVPRVVYHPGGHFLPSSGKQYVAALVAFIREVLGEQADGGMPGSGIATPRKEERVEDMELPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQJ3</accession>
    <name>A0A9Q8UQJ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_07091</name>
    </gene>
    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763126.1">
        <property type="nucleotide sequence ID" value="XM_047906239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQJ3"/>
    <dbReference type="GeneID" id="71986969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07091"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="25131" checksum="FD324CCFC9A8BFD4" modified="2023-09-13" version="1">MSAAKDAKAERAAAATAAVFSVAELLEHIILDVVQDTTPHHALGLGATLSQLTQVSHDFRSIIYDSPKLARLATKTLRISGPVSTYDRLAWLFVEKLGLQLTGPMRYWPRKEHYRLTPRPARYSWLLCKTHERTARMRSFRGGAGNASASWRDIKLTSGAFEICIDIPDVACNYSPRSGRLLEEEGTKNVELEFDTEATLGVAFDKYCEIVDRSMEDREIASGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQL0</accession>
    <name>A0A9Q8UQL0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763214.1">
        <property type="nucleotide sequence ID" value="XM_047906733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQL0"/>
    <dbReference type="GeneID" id="71987463"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07585"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="12189" checksum="68E8904CC7B54006" modified="2023-09-13" version="1">MSQGFRKISRTTPGRTASRPKQQSTRAPQQDNDRDIRELYEAVLARMDYTAQVSLVEKLKRTPPTYMDLDFNMFWLNLRQKDPKCAGYILEVAMRARDNIEKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQM8</accession>
    <name>A0A9Q8UQM8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763290.1">
        <property type="nucleotide sequence ID" value="XM_047906628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQM8"/>
    <dbReference type="GeneID" id="71987358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07480"/>
    <dbReference type="OMA" id="SARNNEY"/>
    <dbReference type="OrthoDB" id="5327951at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="531"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="66282" checksum="8E963B930570508B" modified="2023-09-13" version="1">MSSILTDLSAQQRTQLQEVADLLLQIYETLAELRYVDPESIVRGPHELVHLQETYDRHGLDPSIRHLYTLLPYIDPTQTEARDFFHGGAFFNPTESGDIEQGRDPFYASPQGEDYEAENGPYMRPWFTPLSNMGNHQSVIVYDARLHRIWIVDQEGWGTTDPGLRAEYRKHIGDESEKSDWGNDSSECGYVDDEEGSDDDDSSSHGSSEFWSDDEEEDEEGVNELEQLRQEETEGVDFDEGFEILNDEESREAKEADVSQNTNSFEHIDSRHAGDVLRDINRYYRELKIMPAQGEYNGGEWRLPKEVLVSLYLKHGWPTIFNGEAFEIDQHRAYAAERAKYDAEDPLRQVECYEGWTKYCAQDVERHQQELADAKDVDEEWLARFNLWVVEQRKLRNLEDLKERREKADHLCPGGVCQKEGDLPLWEREWLRVQRPRIDPERRQGESEDAFLARQRLDRNKATIHAKALEAAQADAARLCPGRTFAEATGRKRLGGPGIRERIETETFWVEFSGKEVEKVEKWEEQLPEGAVRAKETVREEIEKNQKALERVVKDVERMERWVEEHGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQT4</accession>
    <name>A0A9Q8UQT4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7605 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763367.1">
        <property type="nucleotide sequence ID" value="XM_047905812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQT4"/>
    <dbReference type="GeneID" id="71986542"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06664"/>
    <dbReference type="OrthoDB" id="3598281at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056024">
        <property type="entry name" value="DUF7605"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24564">
        <property type="entry name" value="DUF7605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7605" evidence="3">
        <location>
            <begin position="716"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="499"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="968" mass="109717" checksum="6A3A3637F9700B1E" modified="2023-09-13" version="1">MSRPPPFGGSPRPRSRDQSVTSRRSWEGSSLFGTPEPTAPGQRTPLLRTTGIISPPASPASTINSYGHILKNGSDTSSILSSDSTVCPSFRPSPRPSPRPSPRTWSQRQDVSEDEGFEEWQDDSDEEYESDCLYSQAQETFPKLPAFDPRLSQLKQQASQLTRDLALLLDPRKYGSNDVSNMVMKATELMQIPAAKKPRIMMLGVTGSGKSSTTNSFVDDLHASRAASTGKSCTCVPTLITSRLPDQSLPYAAEIRFFDPEQQRGFFQQLIENYIRFNFKYDPEWDEDLQLEYSALSASAVKIFQALFCNEQNFDSPGALKVFLDQHHRENNVPSVLDWLLSRTADLLDSRCVMKNGHFTIFHEASTGEGLNEEIDPHIFETSEDLHEPALWPLVRDVTKGLMGNAILEYVEFLDLPGTSDIDLIRSSIATEFLKSCDALWIVTTLDRSISKNDLDQMLKAHSERFGHSIAVIVTCSDANVNDALAVGMHRENQSISQYRELGREISAIKQELDAVKSDRRNTVKRRRVTRLSPEVEVYRARERKLTTKLEKLKDEQFESLVHVRNSFVERQLKATKSQYLVKGVELKVFCISNTQYQAWQGVESGDCRRMSVECTGIPRLRAYALALAAPAELRTAADYITKATVLLKGLSLWVDTDPAQRHAGLMGVIKKPSSILDTEARHFMGQHTTSQQNGEPGSMFTAILNPLYIHRRTHIKAALEVERELETWFFQSLKAFMARDGKHETDRHAAQVWNERFAEQQTTAIERGWEIMLPYYKKKLKGMTEKLQRQLKNTPMELSSLPSAVPLPVSRFEGILNGYSRRIDTSYQTRIAELEKSLSNVRLDATRDVYSAYFTRAMRPVYAEARTIIWQRQQGRIPLATEIFTGRERWRKAVHCCLPGLEERPAVRNYLCGWSAQGRHRNHPRRYGRDVRGHLCQRCTKHLRISCSPRAQTIPGERDAASRAYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR23</accession>
    <name>A0A9Q8UR23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763637.1">
        <property type="nucleotide sequence ID" value="XM_047906713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR23"/>
    <dbReference type="GeneID" id="71987443"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07565"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10111" checksum="F9BB41B80B1B3CBD" modified="2023-09-13" version="1">MASSYEVLQGFFGELSDDWNDLSALDIAPRPQLSYQEQARAVFLPYTQPGTKSFVDVHLSATGASSNYWEAALSYKDKRSNSSKTPTPQSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URI9</accession>
    <name>A0A9Q8URI9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764133.1">
        <property type="nucleotide sequence ID" value="XM_047909412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URI9"/>
    <dbReference type="GeneID" id="71990142"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10264"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040401752" evidence="1">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="19338" checksum="3FECAC0A47973B5B" modified="2023-09-13" version="1">MAQLHITALLAILLLFLSSVISATTVHTYRDCTTSQRENIDEWVAEVMTRIKQVVEADGIPDDWVEPGEQPPTKGEVFHLTRLSIAVLQIPPALTFICPKPGSTVGRYCSDDMAAGSFDASEANWLLPERWDRNSLTLCPAPQIEGHEQKMNTGTIHSVLLNDAEKRLEAREDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US07</accession>
    <name>A0A9Q8US07_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin synthase</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764642.1">
        <property type="nucleotide sequence ID" value="XM_047909238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US07"/>
    <dbReference type="GeneID" id="71989968"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10090"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="OrthoDB" id="10258924at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000004">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000006">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="104"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="104"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO20276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="25000" checksum="35C09E2B468122EE" modified="2023-09-13" version="1">MFTGIVEKIGTVSKLVQNDETSSGGGGTSLTISDCAEILGDCHLGDSISINGTCLTVTEFEKDSFKVGVSPETLRRTNLGSLKEGSGVNLERAVSGSTRMGGHFVQGHVDTIATILKTTPDGNAVTFRLQPKDKGVLRYIVEKGYVTLDGASLTITNVNDDEGWWEVMLIAYTQEKIVMGGKKEGQDVNVEVDMVGKYVEKSVKAYFETNAGDGGAVLEKMVQRIVDGRLKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USB1</accession>
    <name>A0A9Q8USB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764957.1">
        <property type="nucleotide sequence ID" value="XM_047909961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USB1"/>
    <dbReference type="GeneID" id="71990691"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10813"/>
    <dbReference type="OrthoDB" id="3650650at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13256" checksum="95E98B0FCC68D7CA" modified="2023-09-13" version="1">MADNTPTLRQRLESLPQELYDEIYTLTFTAAPGERKICAPTKSESRASTLSPDISRCFRGHDSANLFLVDRASSQMFAESYFGGEGAVFTFHCDMCWTSWLSRLNDEHRRILPSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USN3</accession>
    <name>A0A9Q8USN3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765344.1">
        <property type="nucleotide sequence ID" value="XM_047910648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USN3"/>
    <dbReference type="GeneID" id="71991378"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11500"/>
    <dbReference type="OMA" id="ETGSMNY"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="263"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="461" mass="51080" checksum="98BC92B51CAFD8A2" modified="2023-09-13" version="1">MVRERDSDVPQPGPAVLTSNAGPDEWLEQAKLCRYLPEADMKRLCEIVKECLMEESNIQPVQAPVTVCGDIHGQFYDLLELFNVAGGMPGEVDERAAAAAATAREKEARSKRTSMSSGGAAMFSASDLEPPTQITDPKVKRKMKRRFQKDSAYTSAASEDGSEPGGADDEERRGRMRSRSMNESVDEGEDIEDDGSEDSGVGVRSPEPSRSKSTAQSNKVDHTNGLQNFVFLGDFVDRGYFSLETFTLLMCLKAKFPDKVTLVRGNHESRQITQVYGFYEECQQKYGNASVWKSCCQVFDFLALAAIIDGKVLCVHGGLSPEIRTLDQIRVVARAQEIPHEGAFCDLVWSDPEEVDTWAVSPRGAGWLFGDKVSSEFNHVNNLQLIARAHQLVNEGYKYHFASQDVVTVWSAPNYCYRCGNVASIMTLGEDLNPDFKIFSAVPDHRRAVPAGRQGRGEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USN7</accession>
    <name>A0A9Q8USN7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_11505</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765347.1">
        <property type="nucleotide sequence ID" value="XM_047910653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USN7"/>
    <dbReference type="GeneID" id="71991383"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11505"/>
    <dbReference type="OMA" id="PMQIGET"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="133"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="411" mass="46443" checksum="460407A8900C1AA1" modified="2023-09-13" version="1">MRPEFEPPSSGLTDASGDLSICERAREELQNTVLVIKTGATESRRKVPVHSQTTLRCWPNVLFLSDFDESIGGHQVHDALDHVSEQIRLEHPSFELWRRLHAHGRSAIEISDSETGDNVYWESGTTDMQAGWHLARFMNLAMSVKALEFHPDARWFVFIDADTYISWSGFLGLARTLDHTKPLYVGYPAAMGPNMFFGHGGSGYALSQAALTQVVESYQAQQSRWDTDAVENEFGEVPFAKLLLSIGIDLSWALPHFQRGDPASMDFSMMEHGRRAWCYPAVTYHHVGPDDIRRLHRFEGAWNRTSDGRHFRHSDVYRSMGLPIAMKGDADGWDNLSEHVVEGVDDYASCREACRERQTCVQYSFNLGQCRTSSALKRGRATEGAASGWVVDRVHRMMESLDTRCHGKFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTJ2</accession>
    <name>A0A9Q8UTJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766229.1">
        <property type="nucleotide sequence ID" value="XM_047908579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTJ2"/>
    <dbReference type="GeneID" id="71989309"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09431"/>
    <dbReference type="OMA" id="NPPEVQW"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000058">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="15"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="644"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="743" mass="81051" checksum="BC6CA7E7CA70F834" modified="2023-09-13" version="1">MAVNRLKSVLGTARKGETYELRAGLVSQYAWERKESIQKTIMSMTLGKDVSALFPDVLKNIATPDLDQKKLVYLYLMNYAKSHPDLCILAVNTFVQDSEDPNPLVRALAIRTMGCIRVDKMVDYMEEPLRKTLKDESPYVRKTAALCVAKLFDLNPALCIENGFLETLQEMIGDSNPMVVANSVQALAEIDDTAPETNALIITSQTLKKMLLALNECTEWGRITILSTLADYKAVDVKESEHICERVSPQFQHVNPAVVLAAVKAVFLHMQHIENPTLHATYLKKMSPPLVTLISSQPEVQYVALRNIDLLLQKQPGILDKEMRVFFCKYNDPPYLKFQKLEIMVRIANSHNVDQLLAELKEYALEVDMDFVRKAIRAIGQVAIKIEECAEKAVNVLLELINSKVGYVVQEVIVVIKDIFRKYPGYEGIIPTLCQCIDDLDDPNARGSLIWIVGEYAEKISNAGDILAGFVEGFNEEFTQTQLQILTAVVKLFLKKPDESQGLVQRVLQAATAENDNPDVRDRAYVYWRLLSSDPQIAKNVVLAQRPSIISTIPVLSAPLLDKLLPNLSTLSSVYHKPPSAFLGQGRSSALQEEAIAEAKENARENPIAASAVSAAVAGTTAPIQNTAENLLDIDFDGAAPASMQKAPAMGSSGLEGLAGTPQRVASPSITSPAAGQAPGGGLEDLMGLGDAGPATMNNGGGSQDLMNGFASMDMNDQPPPAQAQLNGGAGSKKTNEDLLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTL9</accession>
    <name>A0A9Q8UTL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766293.1">
        <property type="nucleotide sequence ID" value="XM_047908679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTL9"/>
    <dbReference type="GeneID" id="71989409"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09531"/>
    <dbReference type="OMA" id="AYMITLN"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="186"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="779" mass="89360" checksum="0CF5A96CB9DDF7B4" modified="2023-09-13" version="1">MAVSMLHTPSRASSSSASSYVPVTRQNTMSSQEGSRSMRASKRYSVTALYLSMNANQRDLEIEDDLARAQKALRELKAKISSQSKKNFVLEKDVRYLDSRIALLVQNRMALEEKEEVASHLDDSLDLTEGSFPNDEKTQKYGNLLFLLQSEPRHIAHLCRLVTMAEIDQLLQTVMFTIYGNQYESREEHLLLTMFQSVLTFQFDNTPDYSSLLRANTPVSRMMTTYTRRGPGQSYLKTVLAERINSLIEIKDLDLEINPLKVYESMIGKIEADGGTLPANLPKGITAEQAAANENVQRIIAPRIDMLIEIATSFLDTIIEGLEETPYGIRWICKQIRSLTRRKYPDAQEQTICTLIGGFFFLRFINPAIVTPRSYMLIEQTPAENPKRTLTYVAKMLQNLANKPSYAKEPYMQKLQPFIQHNKERINKFMMDLCEVQDFYETLEMDNYVALSKKDLELSITLNEVYAMHSLLDRHNKELVKDESSHLNQLLGELGPAPAQLPRKENRAINLPLYSKWETSLDDFTAALDITQEEVYFMEGKSTFVMIMRSLPAGSMVMRRPLKLDRIAEAAATTKNDSVMVRKGIRAMELLNQLQELGVIDKDDSYAMLRDEVEQELVHLGSLKEKVIAETSKLDEVFRTIRDHNAYLVGQLETYKSYLHNVRGQSEGTSKRNQTTKVLGPYKFTHQELEKQGVIQKSNVPENRRANIYFNITSPSPGTFVISLHYKGRNRGLLELDLKLDDLLEMQKEQQEDLDLEYVQFNVSKVLQLLNRRFARKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTS1</accession>
    <name>A0A9Q8UTS1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09677</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766443.1">
        <property type="nucleotide sequence ID" value="XM_047908825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTS1"/>
    <dbReference type="GeneID" id="71989555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09677"/>
    <dbReference type="OMA" id="KTQRYGT"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000006">
        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="8"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO22077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="453" mass="48438" checksum="1E4621E5217C060B" modified="2023-09-13" version="1">MSLTNSSPEQAARAAKVSSRKLATLSVNARNNALDAIHDALSNAKDSILAANAEDLAKAKQSTANGELNASIYKRLDLSRPGKFDDMLQGIRDVKGLPDPVGRVDLRTELDDNLILQRQTCPIGVLLIIFEARPEVIANIASLAIKSANAAILKGGKESTESFKTIANIISQALQKTEVPSDSIQLVATRDAVGGLLEQGEFIDLCIPRGSNELVKYCQQKAHMPVLGHADGLCSVYVHSDAEVGMVVDVVVDSKTDYPAACNALETLLANEDALETVLPSLATALQAKGVTLKCDAKSKEALTKALDKDQSSQLQDATDQDYDTEFLDLVLAIKTVSSVSEAIEHINTHGSHHTDAIVTASKEIADQFLNGVDAACKFWNASTRFCDGMRFGFGTEVGISTNKVHARGPVGLEGLTIHEYRITGNGQMAASYGTGAGKRQYKHKKLELPNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVJ5</accession>
    <name>A0A9Q8UVJ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13144</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with histone H3 and histone H4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ASF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768407.1">
        <property type="nucleotide sequence ID" value="XM_047912292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVJ5"/>
    <dbReference type="GeneID" id="71993022"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13144"/>
    <dbReference type="OMA" id="CSYDERE"/>
    <dbReference type="OrthoDB" id="29755at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000001">
        <property type="entry name" value="Histone chaperone ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017282">
        <property type="entry name" value="Hist_deposition_Asf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037759">
        <property type="entry name" value="Histone_Asf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="154"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="226"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR037759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="281" mass="31233" checksum="D75A80098BEC10F1" modified="2023-09-13" version="1">MATVSLLNVNVRNNPAAFNAPYEFEITFECLEPLQKDLEWKLTYVGSATSSDHDQELDSLLVGPIPVGVNKFVFEADPPNTSRIPASDILGVTVILLSCSYDEREFVRVGYYVNNEYTDPAMNEEPPAKPDLDKIRRNILADKPRVTRFQIKWDSEESAPSEFPPEQPDVDQQDDDEEAYAKDELEEEAQDEGAPLEGDAEALATAKVDEDAEMEGADGNDKGEESDAASEDLEAESEDDEDDEEEEEEGTEENGDAMDTEMGDSHPHQQQAQQPADVMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW02</accession>
    <name>A0A9Q8UW02_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid hydroxylase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768869.1">
        <property type="nucleotide sequence ID" value="XM_047913153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW02"/>
    <dbReference type="GeneID" id="71993883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14005"/>
    <dbReference type="OMA" id="QYAHPIE"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="120"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="28186" checksum="4D60089DB1CE61D2" modified="2023-09-13" version="1">MYARPQEIWPRLLQHAPPALIELSGLLCIQFVGFWLPSMILLGADFWNMPGSRKHKIQPPARQPTREQISRCISTVLSNQLMAFTVKITELGLLRLLGKQSFYRYDAALPGWHELCRDIAGCVIICEVLFYYSHRLLHSRHFYRRIHKRHHEFAAPIAIVAQYCHPIEHLLSNLVPFWLPPYLLGCHIITCFIFWTAGVTETIIAHSGYDFFATLSKAHDKHHEKFNINFGTLGFLDWLHGTSG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-12-05" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>P0CU69</accession>
    <accession>A0A9Q8UV48</accession>
    <name>CLAK_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase claK</fullName>
            <ecNumber evidence="7">1.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cladofulvin biosynthesis cluster protein K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">claK</name>
        <name type="ORF">Clafu184397</name>
        <name type="ORF">CLAFUR5_12903</name>
    </gene>
    <organism>
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2014" name="Mol. Microbiol." volume="92" first="10" last="27">
            <title>Functional analysis of the conserved transcriptional regulator CfWor1 in Cladosporium fulvum reveals diverse roles in the virulence of plant pathogenic fungi.</title>
            <authorList>
                <person name="Okmen B."/>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="van der Burgt A."/>
                <person name="Cox R."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24521437"/>
            <dbReference type="DOI" id="10.1111/mmi.12535"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2016" name="Proc. Natl. Acad. Sci. U.S.A." volume="113" first="6851" last="6856">
            <title>Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Saccomanno B."/>
                <person name="Vaisberg A."/>
                <person name="De Wit P.J."/>
                <person name="Cox R."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27274078"/>
            <dbReference type="DOI" id="10.1073/pnas.1603528113"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2014" name="PLoS ONE" volume="9" first="E85877" last="E85877">
            <title>Secondary metabolism and biotrophic lifestyle in the tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="Iida Y."/>
                <person name="Karimi Jashni M."/>
                <person name="Battaglia E."/>
                <person name="Cox R.J."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24465762"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0085877"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2018" name="Mol. Plant Pathol." volume="19" first="369" last="380">
            <title>Down-regulation of cladofulvin biosynthesis is required for biotrophic growth of Cladosporium fulvum on tomato.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Overdijk E.J.R."/>
                <person name="Saccomanno B."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27997759"/>
            <dbReference type="DOI" id="10.1111/mpp.12527"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="1 3">Oxidoreductase; part of the gene cluster that mediates the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:24465762, PubMed:27274078). The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG. The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078). This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078). The cytochrome monooxygenase P450 claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Pigment biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="1 2 3 4">Expression is positively regulated by the transcriptional regulator wor1 (PubMed:24521437, PubMed:27274078). Expression is down-regulated during biotrophic growth within tomato leaves (PubMed:27997759). The expression is induced at later stages of infection when conidiophores emerge from the plant and produce conidia (PubMed:24465762).</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767853.1">
        <property type="nucleotide sequence ID" value="XM_047912051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CU69"/>
    <dbReference type="SMR" id="P0CU69"/>
    <dbReference type="GeneID" id="71992781"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12903"/>
    <dbReference type="OMA" id="DNIPGCH"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF37">
        <property type="entry name" value="OXIDOREDUCTASE MDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0503">Monooxygenase</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000445889" description="Oxidoreductase claK">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000269" key="1">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="24521437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="27997759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="6"/>
    <evidence type="ECO:0000305" key="7">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <sequence length="270" mass="29610" checksum="B332A0755965A662" modified="2018-12-05" version="1">MDSKVTTYAVLGSTGNCGSALIRNLLGKPQSRVHAFCRNKKKLLRLIPEIADSKQVEVFEGGMQDHDLLAACIKNTRAVFMCISTNDNVPGCRLSQDSAIALVKVMRELGYDKPDGGPNGPAPKLLLLSSGTIDPHLSKHLPSLLLWILKRSASHVYADLEKAEEFLRAQESWLTTIYIKPGALSVDKKRGYELSLTEQKDPVSYLDLSAGMIEAADDPEGRWDLKNISVNCGSTPAGFPDGTILCILMGLLRHYFPWTHAYLPMGMGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4M1</accession>
    <name>A0A9Q8L4M1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Negative regulator of the PHO system</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Serine/threonine-protein kinase PHO85</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_01581</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with a number of cyclins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755161.1">
        <property type="nucleotide sequence ID" value="XM_047900729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4M1"/>
    <dbReference type="GeneID" id="71981459"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01581"/>
    <dbReference type="OMA" id="NWQIFVP"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000062">
        <property type="entry name" value="PHO system negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000410">
        <property type="entry name" value="Probable PHO85-cyclin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="9"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO10795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="36670" checksum="84DFB239C46F342A" modified="2023-09-13" version="1">MDKRHPSSFQQLEKLGEGTYATVFKGRNGQTGQFVALKEIHLDSEEGTPSTAIREISLMKELKHENIVSLYDVIHTENKLMLVFEYMDKDLKKYMDSYTNPVGGARGALDAATIKSFMWQLLRGIAFCHENRVLHRDLKPQNLLINAQGQLKLGDFGLARAFGIPVNTFSNEVVTLWYRAPDVLLGSRTYNTSIDIWSAGCIMAEMFTGRPLFPGTTNEDQLLKIFRLMGTPSERSWPGISSFPEYKQTWPVYATQELRAYLPQVDSLGLQLLGQLLQLRPEMRCSAQQALAHPWFAELNARSQQAAQGGFTQPQGMAVSQQRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4V9</accession>
    <name>A0A9Q8L4V9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755277.1">
        <property type="nucleotide sequence ID" value="XM_047900012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4V9"/>
    <dbReference type="GeneID" id="71980742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00864"/>
    <dbReference type="OMA" id="YGSVHRQ"/>
    <dbReference type="OrthoDB" id="10068368at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14232">
        <property type="entry name" value="GAT_LSB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16980">
        <property type="entry name" value="VHS_Lsb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044103">
        <property type="entry name" value="GAT_LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF1">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="3">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO10911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="46187" checksum="0039FF33312B96E4" modified="2023-09-13" version="1">MFSGSSKKPYTAITALIDRYTSEQYEEDDIGGVIDLVDVIRIQESGPTEAARALRKKLKYGNAQRQIRSLVILDGLIQNAGGRFQRTFADEPLLERLRLMARDDMVDATVRQKCRVLFAQWANAYRNTAGLERIANLYKEFPKTSRPEAARQKVLREIPADPDQESPFAEPSSSSRSRSNLKDKQLGQSAAPSRPVTLTPTSSGFSYKLFKEKKDKTGKPFSLSKEKENMTTSIAQASIASTNLMNGLQLINRESERVSNNIEVLKRVEACKNLRRKILYYIQHVESDEWIGSLVNANDELVKALTTYEIMDRSISDDSDSDAWENADGIKGSGGHARTSSAQHQLAGLSLSEAPPVKPPRPAAPAAISMPSRPPVPAPVASAKLDDDDEDDDDPFGDSHAAKTPFDERAGMTWREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4X8</accession>
    <name>A0A9Q8L4X8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01704</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755259.1">
        <property type="nucleotide sequence ID" value="XM_047900852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4X8"/>
    <dbReference type="GeneID" id="71981582"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01704"/>
    <dbReference type="OrthoDB" id="4525788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="45"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO10893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="453" mass="50885" checksum="B256B02C0679344C" modified="2023-09-13" version="1">MQIPPVDVTVSWPTPNYDDPKTRGDALLVLLVLFSILVFFAVFGRYYSRIIIKKWFGWDDAMITLAFVFTIGMNATVMLANRRYGWDRHVWDVKPTLYQNASIVAFAAKLLYVEAATCTRMSLIFFYYRLVRDSGIAWFAWVLHASMFFVVGLGIAFTLLGIFLCVPVQAYWVFPPMAGHKCLDEGTATLIVGIFNCCADLLTTVLPIPLVVRLTMPVRQRLGVCMLLCLGVLVTVAGIVRTYYIWQSLINSWDETWFSYPLWICAAIEIDVGVVSVGSHSPLKVLADKQSDMRHKCAPALKPLLHKPMSRVSSLVTSKLSSLRTLGAAPKIPKDLSKSTRSTKSTFRPPFAKRSGGDSIWDGDEEYGMLRLDRDGTEKGPTAVYVPDNVREVESRTSIIRQWSNKRPGAPRRQPTLEIMKTQEIEQVSYAAGEEPQGSECSTQRTPDAVEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5M1</accession>
    <name>A0A9Q8L5M1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755550.1">
        <property type="nucleotide sequence ID" value="XM_047899525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5M1"/>
    <dbReference type="GeneID" id="71980255"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00377"/>
    <dbReference type="OMA" id="ITLSMRW"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040320457" description="CREG-like beta-barrel domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="3">
        <location>
            <begin position="44"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="30396" checksum="AF677BD615750A90" modified="2023-09-13" version="1">MKSLILISTLLSVVSARSSPQRPAPPSHHVFSNPPAHDEGYRIPTLRESAAMARKIMHLSTIGDLVSVFPEQTHTNELDAQENRPADIAGSPIGLMEYYADCDPLSGNPILLAINIATPYKNYNQGSNISLGIRWWPIEKNHYSLWTSDDDEDIPTPHTPAALPRFSLHGRLERLSEERLKDGKIRECFLRAHPDSICWQPGNEISHESEYVQLVVDHVYWFGGFGDRARIGWLSIEDWRNLTMEEVIKAKLPGEKKAKPSWWREWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L625</accession>
    <name>A0A9Q8L625_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755249.1">
        <property type="nucleotide sequence ID" value="XM_047901258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L625"/>
    <dbReference type="GeneID" id="71981988"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02110"/>
    <dbReference type="OMA" id="MHLPYIH"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="36698" checksum="ADABB85B7CF6224F" modified="2023-09-13" version="1">MSSSSFVRQASHAGSWYSDSKARLSSQLDGWLDAVNPPVTCIGPQSDGQTQTELPVSGARMIIAPHAGYSYSGPAAAWAYKSWDVSKTKKVFLLGPSHHHHLSKAALSRCTEYATPIGNLTVDRKLTAALHETGQFEWMSQSVDEDEHSLEMHLPYIYKRLSQTFGTDPANFPPLVPIMVGNTSASTEKSLGRILSPYLADPGNAFVISSDFAHWGSRFRYTYYRPSAGSAINLTSSAKSPKDPAIHESIKAVDFECMGACESGSHETWIDTLEETGNTVCGRHPIGVMMAAVEKLRKDRNEQDLGTFKFVQYDRSSLVSRVGDSSVSYASAYAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L639</accession>
    <name>A0A9Q8L639_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755867.1">
        <property type="nucleotide sequence ID" value="XM_047899189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L639"/>
    <dbReference type="GeneID" id="71979919"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00041"/>
    <dbReference type="OrthoDB" id="5314997at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="187" mass="21738" checksum="D4A850BB7B662871" modified="2023-09-13" version="1">MANTFAFLELPLELRRMIYTKYFNLMPVQHDEWSTCSGRTYSRHNLSKTCRQVQTEYLSEIWRSDRLQICVRGTGGCAQKTRRWLQLMGPAVIPLVKHFHFWNALRKPDLGIKIEGSRAIVGVDSFFVQLDAPAMMNLGRKCSYVANWGLRKMPGGSWYVTKEVIEEIMLLMDRTLTDNELYTCMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L737</accession>
    <name>A0A9Q8L737_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Biphenyl-2,3-diol 1,2-dioxygenase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756391.1">
        <property type="nucleotide sequence ID" value="XM_047899438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L737"/>
    <dbReference type="GeneID" id="71980168"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00290"/>
    <dbReference type="OMA" id="WDHEHHR"/>
    <dbReference type="OrthoDB" id="5371818at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050383">
        <property type="entry name" value="GlyoxalaseI/FosfomycinResist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366:SF14">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21366">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="16"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="19936" checksum="A8BFDD5B35A33BF0" modified="2023-09-13" version="1">MTLTNGTTSKVLSPSNLAHIVIRTSNLPKMVSYYQNFLGAHTAYENEMLAFLAYDDEHHRIALLNIPGLEKNDEKHCGLEHIAFSFDTLRDLCTAYEQRQALGITPGWCVNHGPTTSLYYRDPDGNQIETQVDNFETAEEATAFMNSPELRRILSVWILIRRSFANVWKVGRMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L770</accession>
    <name>A0A9Q8L770_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="19">GPI-anchored hemophore</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_00665</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756506.1">
        <property type="nucleotide sequence ID" value="XM_047899813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L770"/>
    <dbReference type="GeneID" id="71980543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00665"/>
    <dbReference type="OMA" id="VSDCAQM"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040287460" evidence="17">
        <location>
            <begin position="17"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO12140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="263" mass="24644" checksum="D27D81C2745279CE" modified="2023-09-13" version="1">MKTFILVAAGAALATAQMTLNDIPECGRNCVNAMIGKSQTLGCQAADASCLCGNANFGYGLRDCSNEACGSTIGQQVVSYGVQYCQQALGSASNAQSAGASSVLAGAAGASGADASGSGTAAATQTEGGDNDASQTGSAITTSALTALVSQSDTTFTTTTGSTTIYEGQETGGAGGIGGAISSATDSAASAASSAESSASDAAGSAMTSASDAADSAMSSASEAANSASDAAASATDSSSAAGAMITAAPMLAMGALAALAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7C4</accession>
    <name>A0A9Q8L7C4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF2421 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756627.1">
        <property type="nucleotide sequence ID" value="XM_047900330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7C4"/>
    <dbReference type="GeneID" id="71981060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01182"/>
    <dbReference type="OrthoDB" id="2274698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994">
        <property type="entry name" value="ARAE_2_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994:SF4">
        <property type="entry name" value="ER TRANSPORTER 6TM N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="7">
        <location>
            <begin position="248"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="6">
        <location>
            <begin position="385"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="72251" checksum="4730BE2F6CFBE8D4" modified="2023-09-13" version="1">MSSTINGAFKHVLITLEIEKPSKKVQDEESTGSAATPGATGFAEAYKKQLDDFYESKQRSLREWCHAHSIELPEDFFESSFLRPESIHIESEHVRETTQRQLFFALYVEYLLWRAGLAALELVLYVDKRKQQGAMSKTMLIFPGAKTLRKWAVAMVGREDTSDEDRLTSDLDSAGTNNLYLGESYSRRKDPEHLPPRNRWERIGDFIRLLPQALRSDASAFGFRVVCATMSIGIICYLEVSQTFCLENRLLWAMIMVPLSMTRTASQSTWSFALRILGTAIAMTASYAIWYVVDGMTPGVIVFLWLWIFLAFYVVLKFPKFVIVGILSIVTSILIIGYELQVREIGIAASTSNGQPAYPIYLLAPYRLATVCAGLFIAYFWTIFPYPVSESTELRKDMGAALYLMANMYSVVHETVKSRIQKTDGDQNFKGSRAYHLEKARQQVFTKLIGLLTALQQNSAFSKVQIRIGGKFPHEEYDDLIKCLRRVLQYTAMIAYASNTFSTSSAESQWSQDFRKLLSSINATSHGLTHLLALLSSSMIHARPLPPYLEVPQHGKYIKTLEAIDVDILSVRHIVEPEYSAFAVTSICAQCINDDIVKITKHVKTLVGEIDFSFHVISTTEENSDESSLSSSEEKKAKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L884</accession>
    <name>A0A9Q8L884_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-dependent mannitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00999</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756344.1">
        <property type="nucleotide sequence ID" value="XM_047900147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L884"/>
    <dbReference type="GeneID" id="71980877"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00999"/>
    <dbReference type="OMA" id="NPMRRMG"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="32035" checksum="E7EAFD92BF24342C" modified="2023-09-13" version="1">MATNGDTVGRDDLTSRTLPFMKLSDGSEASMTSPPPPLPHYLNAEGRALARFAVEGNVVITGGAGTLALSTARALLEHGAAGLCLWDLEATLRSAQPAIAKLASEFPSTRIFSIAVDVTDDEAIAEAVTSVVQTFGTLDHLFCFAGIVGCYHAMDMSTAQWRKTLDVNTTGSFLCAQAAARQMKSQGSGGTITMTASISAHRVNFPQPQVGYNVSKAAIVALKSSLAAEWAVHGIRVNSISPGYMDTILNAGDGNIAEARASWAAHNPMGRMGQPPEVEGMCVLLASRAGSYINGADMLIDGGATVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L916</accession>
    <name>A0A9Q8L916_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidoreductase phnG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01303</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757398.1">
        <property type="nucleotide sequence ID" value="XM_047900451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L916"/>
    <dbReference type="GeneID" id="71981181"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01303"/>
    <dbReference type="OMA" id="QATHYIL"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="394" mass="42056" checksum="130E1E9B3FDEA8DF" modified="2023-09-13" version="1">MTQTRNIVILGTSFGGLGAAHYLAKHVLPQLAKSQDTKYVLHLIDPSTRFWWHIAAPRQIVSLEQLTIESSFVPIMDGFKQYGSLLDSIKFHHGSATSMNKDSRTVTISLHEGGSESLDYYALVISTGIRSPTPLTTFHGDYTISEKAIKDMNAKLSTAKDVVISGGGPVGVEMAGEIAMHLKGKAKVTLYSGSDKILPVFKQSRAAKAQMLLEKAGVTVIHNVKITGSGQAGDGRTEISLSNGKAVHADVYIPCHGVTPNADFVPAELKGGNGYVQTDPSTLRVDAAGPRVYAAGDVAGVDKGGVLNMYNSLPVLNANIAHDLLAEAKLGSVAEKKYTFKPSETQLVPVGPKTGVAAFNGWGMPGFLVGLIKGKDYMLSQMENFTEGKKFLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L960</accession>
    <name>A0A9Q8L960_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757524.1">
        <property type="nucleotide sequence ID" value="XM_047902086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L960"/>
    <dbReference type="GeneID" id="71982816"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02938"/>
    <dbReference type="OMA" id="ADETPRM"/>
    <dbReference type="OrthoDB" id="4194555at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1101" mass="121604" checksum="7F80142205C8F418" modified="2023-09-13" version="1">MENKTPPNPLSPLAEDSSHTFVADNNSAIPLPPAPPPGLLSRLIRSARRAPPLNMNPTANTFVPHARLPPKRKATSSARSRKSVHSSAPRGDSSHYLSMDTPIIRSEDLFGKDNLTQRSDSFDGLVDGEASLETFQMDLQEFAQRPNGTSRDAMREALTLLRTQARDRVKKTSEPIQSSSAILFTQDAPGSAHGAASDLDRLRYLPLRPAAATSGSRDDCLNNNTILTVLPTHRQRIDQATDQQIASRAHWHVNMLPVELFELITTYLSRDDIKSMRLVTKEFEAKVSATLFNTSVVPFNTELYDMIDEDRKAVRRGSNNIPRYQGKGKGRARDFPDPTQDLLPGGLHWQNAKEDADGKVYKGHGLRVFQGFGRHIKRFGMSFEVAESQLAHPPIKRELDHVQAYHGSYDWPPFQYTRFENLAGLERTADETQRMRSAFSNLKSVKEVALSIDSGLGWLSGPDKSLKAHIFLRPSDVFGQSGAVEDHRMLDAKLFWAAIQACHRGLGVSTNLKELSLGQKSLSKSPTELPGLHDTCYANSKLWSSIAASNVLPAVSYNSAEGAAHGILYTTPTQPDFTVQPLFDRSALIPSELRKEQKEWLMETEWAQRAFLECYMLAITDNPARFHGVKTLNIAKLSSGFMPLLARENFWDALPGLADVTIHVKPDWRIVEKDNAGFAEVHGRNPSEAIRIFHRVLLRDRVCLRPSIKKLNIGWVSGGEHADGIFARNANILPAPITQLEHSSAHRANASHNFGLMFDHLEELTLYNCWMTPPTLAELVKNHSSKALKIITLDSVSLTAHPRFSVGGQPGAPLPPHIAHMIAAGGGVGHNLQQLLNAQQGNAQLQAQAQGQAQIANQFAANLPGAQANPQNFQAHLLQQQQQLHQLAQQNGVAINPNPPAAAPVPAAPFQGGAAQHLAQNNVFGNPAPAPSHWSEGHREGSWPEVLDKLSPGLVFDDYLPQPAPWETQRPERPETALQTIELKSCGYAKLNNNTTFDQFALEANHDHHFSNWFRARQTALQPAMMSASSDRYLARIVQYMPQRELDALLYAWGLTHGWNDGDKAEEAEYDGFLPGGTGRVSGKVRKGMPLLGQPPVLGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L968</accession>
    <name>A0A9Q8L968_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_C19"/>
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    </dbReference>
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        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Papain-like_cys_pep_sf"/>
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        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
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    <dbReference type="PANTHER" id="PTHR24006">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="111"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="52215" checksum="CB8105F3C834043F" modified="2023-09-13" version="1">MARTKTEASRHATLREICSNISRETLDVALSKLSEDAASELLQAVSTVVVAKPMPARKKTSTSSSGPRQSGVSKKPRKPMKKNPYARRKKKPAASQPTPGWTVDAANAASKGLYNEGTWCYRNALLQCLLHMPAYCNALAIMHPKCTLGARRCVRCALKSVATRYWGRSQFPANAFANPGADLDAALRRAISPEDVRIGEDIHRPMQSCPFDIWEVGFVEQLHGGKDTTNKDSPMITSTFQIQTKEVWTCHTCLRFYDNVASVTERGIDVGITKPKPGLPLEEYIDNEWATWDVPRTCENPACADSAPGSSDRPPQIMRRIITSGPDVLVIRFRRFGFKTNKTGEEITVPTIVDGKTMMYRVEDRLDHVTSFPEELDLSQYVEGDARLVYKIEGVVSHRGQTIERGHYVATVRRKNGRGINIVNDSRVIEVRNKKRFIDMMNDPGKADEDYKDFRPCVLFYRKTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9G7</accession>
    <name>A0A9Q8L9G7_PASFU</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">CLAFUR5_02933</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757530.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9G7"/>
    <dbReference type="GeneID" id="71982811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02933"/>
    <dbReference type="OMA" id="NTWHEAP"/>
    <dbReference type="OrthoDB" id="19394at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAM1_N"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="627"/>
        </location>
    </feature>
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        <location>
            <begin position="639"/>
            <end position="802"/>
        </location>
    </feature>
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        </location>
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            <end position="292"/>
        </location>
    </feature>
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            <begin position="795"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="194"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
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        <location>
            <begin position="836"/>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="889"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13164.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA39</accession>
    <name>A0A9Q8LA39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA39"/>
    <dbReference type="GeneID" id="71982776"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="199" mass="21737" checksum="5D9494A5D5FB3014" modified="2023-09-13" version="1">MHLFFTTTPPLPLILLFTMHIPTITAFSLFASLGFSQTVLTSPEPTAPGLVFLYTAYVDCLESLYETQGPRDIRKAIPIVGGNFTGPRLSGKILDLGADWGVTDPQTGLFEADTRYNLQTDDGANLWLQTSGPSVPAGGLHLKVNIDTGDKRYYWMNNIVAVGVLGRVAGNDTAFTLKIDVWHLEGEYTNTTFVNGTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAJ3</accession>
    <name>A0A9Q8LAJ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chromatin modification-related protein EAF7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758306.1">
        <property type="nucleotide sequence ID" value="XM_047901886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAJ3"/>
    <dbReference type="GeneID" id="71982616"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02738"/>
    <dbReference type="OrthoDB" id="5595141at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="87"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="285"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="45355" checksum="5207060FF4A3803B" modified="2023-09-13" version="1">MPYRRVFPPTSCRNPHSESLACDESRRWSRGCTVQRVKLLAANMNFCRPGLHVTQHYCTAIASEAACMASRRIPLEKDRKWFARLQAKSGANDQPSASEDTTKMPPRKKARVSQATSPDPEPPQKTPTPGLVSPGKGDEAGLNDAWTDDEEIGLFKGLMRWKPTGIHKHFRLMALHSWLLDNNYIHPRSQHTKPAGIWAKLNTLYDLPALDAREDARQLSPLTTSPEQEEKLDKDSDDESDGYSLAANKIDSEDFALPPEHDFENMMWKARFAEHNEDSELEIPEVNMAEEPPVRFTPSFSIEPSEAATTPQSKRGKKGKGRGAAAAPQPRRSSRMTESVKDAEEENEGEAEKSAEEEAEDEDEEEEESADEAESQASTPGPRRARSTKPTRGKAGRGRGRGRGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAS4</accession>
    <name>A0A9Q8LAS4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758350.1">
        <property type="nucleotide sequence ID" value="XM_047902623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAS4"/>
    <dbReference type="GeneID" id="71983353"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03475"/>
    <dbReference type="OMA" id="KSTRICR"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053212">
        <property type="entry name" value="DHP_3-monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054707">
        <property type="entry name" value="DhpH_subs-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469">
        <property type="entry name" value="MONOOXYGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469:SF2">
        <property type="entry name" value="OS06G0597600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22607">
        <property type="entry name" value="FAD_binding-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="2,6-dihydroxypyridine 3-monooxygenase substrate binding" evidence="6">
        <location>
            <begin position="203"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50957" checksum="077411853CCF0287" modified="2023-09-13" version="1">MASLESGKSDLKPLDVLIIGGSLGGLMAGILLKRRGHNVRILEQAESSEREGLAAGVGLSFHVKAFFETEDRLKDRPLGVANDAFYVLDWNMDVKYKLPTKTNLTTWDSAYYRARANFDRYASSYVPDPPPVDAESNEGEGIYLTGKKVTKVDDIDGRMTAIVQNAQSGEVEHYQGDIVIAADGANSPIRRQLNPGLEREEPGYVIWRGTVPTKDLRQELLDKIEDKPIIWPGQHTYCVIYTIPGNNGSLKPGERYINFAWYFWPTQFSLRDIMTDSDGHYHRTTIPKGKLQPDIWKSQLEQARRLLNPELVELAEHIKEPFVSVISSISAPKAAYFNNRLFLIGDALTQSQPNVGMGTSLAAFAATTLVKEVICPPSQSERLGKDRVAEWERKALQETELTRLRSVSFASWYLNSWPMIGWYFARYYFEQYWQRWIGRRTQAFSVFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBB2</accession>
    <name>A0A9Q8LBB2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757979.1">
        <property type="nucleotide sequence ID" value="XM_047901627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBB2"/>
    <dbReference type="GeneID" id="71982357"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02479"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="326" mass="35944" checksum="AB314AAC108CAB21" modified="2023-09-13" version="1">MAQPCHAVVLRDFSQYGQKATLISEHSSVGSANLNAQRCAQDLAGGAQRIEVTYHHFGGYSAYCQTGEVHREPFELEVVRSTRRDASRPSVPPSAGTSNVVNLQGNTSVLFNKSQSIHTGGRHHPGVATGSGLQQQQQPAQPRIPSNGHQVLPHAHTLPPIAPLLQHASQQPTQKATVPIAAPPKSSSLQRPYVAYTLTRVDYDHWEDDAKEETHVLGVFLDLKEANAAARKHTEREYKRAEVDNGCAETPSEDKNYADGVVLECRTYQDDRDHFIVEVKAFQIDMLDDGYEDTESEEEDEDEDEDAGDEDEDGDAGGPPPKKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC20</accession>
    <name>A0A9Q8LC20_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S9, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02484</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758971.1">
        <property type="nucleotide sequence ID" value="XM_047901632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC20"/>
    <dbReference type="GeneID" id="71982362"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02484"/>
    <dbReference type="OMA" id="RESAMWA"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="37192" checksum="3D32A2641B2AAA20" modified="2023-09-13" version="1">MESNLVRNGCRRAVAVCQTASRRRTIHQSSRCRATPIERQGDIKAAPPVRLNKDPNQFGRGRPRAQLVENEDSRNDPESRQRAMLRRIRIVPASPSYFTATPKYTDDLLELTALLRKYQTLPTLPRGEAPSVRWKSRDLYKIETQENVRAKSYNTLVELLKRLNYIHPSLIPAEVTEALDRYKRLVQPHLNTPNPIVIDQYGRAKAVGRRKSSKAAVYLVEGDGQCLINGKKLTDFFGRMHDRESAVWALKATQRLDKYNVWALVKGGGTTGQAEAITLGVAKALLAHEPALKPALRRAGVVKRDPRRVERKKPGKLKARKMPAWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC42</accession>
    <name>A0A9Q8LC42_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">(3aS,4S,5R, 7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759048.1">
        <property type="nucleotide sequence ID" value="XM_047907293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC42"/>
    <dbReference type="GeneID" id="71988023"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08145"/>
    <dbReference type="OMA" id="RAKPKAW"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="358" mass="38392" checksum="4DAAB49FCAD6A3FE" modified="2023-09-13" version="1">MASPQQIRTVTTDLLKINHPIMLAGMNVAAGPKLAAAVTNAGGIGVIGGVGYTPDMLREQIAELKGFLKDKNAPFGVDLLLPQVGGSARKTNYDYTKGKLGELTDIVIDSGARLFVSAVGVPPKQIVDKLHKAGILYMNMIGHPKHVKKCLDLGVDMICAQGGEGGGHTGDVPTTVLIPEVVRLCKNRKSPMTGQPVQVIAAGGIFNHQTLAAALALGASAVWVGTRFVLSEEAGAPKAHQEAVKTAGFDDNVRTIIFTGRPLRVRNNPYIQNWEENRQNEIKELTSKGHIPVEWDIERMGDDVDDDTMDNARPFLMGKAAAVVNERDSAKKIIDDMVGGAVEVMQKNVSFITSRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC88</accession>
    <name>A0A9Q8LC88_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759076.1">
        <property type="nucleotide sequence ID" value="XM_047907814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC88"/>
    <dbReference type="GeneID" id="71988544"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08666"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052733">
        <property type="entry name" value="Chloroplast_QOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013:SF1">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="20925" checksum="EA3231E99A864637" modified="2023-09-13" version="1">MSTDASGQTGNVPSPVPFIKPGDRVLIDGGSGGVGTFAIQFAKLAGAHVTTTCSGRNVERHLSQLKKQSESAGPFNLIIDNICNDFDLYWKMHTISKPKAKYMMVGWGPSLSCIDFIMQATFTRGFLGGGHHQLQVFAAGNKTEEHGKIATWIAEGKVKPVIDSKFLMEDAVDAFRKLKSGRAGGKIVVEVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD11</accession>
    <name>A0A9Q8LD11_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759527.1">
        <property type="nucleotide sequence ID" value="XM_047907024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD11"/>
    <dbReference type="GeneID" id="71987754"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07876"/>
    <dbReference type="OrthoDB" id="3163292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="22863" checksum="52AF4114DADF5C3B" modified="2023-09-13" version="1">MAKAGVEPRLPSVFSLVIPLSSISGINTHTASQTEDDTPRKRQKLAIAAHDSSNGKTARHSKSCSNCRRLKVKCEAADQAHECSRCARLGLSCLREKKSWIHGEAETVPMQLTIIKLGRALEDVLEKPNMPALDLYASPSIVRPRAPPRATRPNSQEPTERKERSVSPDPMSSLIEATQLNGMRSQLRSVKLRRKGGMRRRDHDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD84</accession>
    <name>A0A9Q8LD84_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_07772</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759639.1">
        <property type="nucleotide sequence ID" value="XM_047906920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987650"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07772"/>
    <dbReference type="OMA" id="SWAPFQK"/>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.440:FF:000001">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.450:FF:000002">
        <property type="entry name" value="Putative non-repetitive nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="14">
        <location>
            <begin position="102"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="13">
        <location>
            <begin position="665"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO15273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1365" mass="152908" checksum="9A9EDA2292197902" modified="2023-09-13" version="1">MAAAAGPQTPQRPLPGAFTVTPAPQGQTIFAANAASLRQNLQPQQVETSGTTSATQQESNVERAAKTIHLALDGDQKYPALEDYITQGISGEYDLPSGQAWQPFQKLKMHDLPPRLLEQANHASMDNQMGVFPALTHAWVALDNCLYLWDYTLPNPEIIGWEENSHPITAVKLVKPKPGVFVADIKHLIVVCTATEMLFLGVAAQTTSTGAQTVALYNTRMAIPVRGIGVQHITASDQSGRIFFTGSASEDIYEFQYQQDEGWFRGKTSRICHTKATMSFVPENLMVVGSMFGSAAKTTYVTQMVIDDSRNLMYTLNTASEIKVYLIKDRLESSLRRPLSGLLQNTGHFNHRTELLTGRDVKLVGISVIPRAEAGKVALVATTSTGCRLYLSLTRGYGYDASAENPPSSAQILHIRYPPKDPAAPRAPAQPSQTTAMTPYGQQPEQVDTNTRYLDGMHKAFRFSPGYWMAFAEDPTDPQRKDRVFLTATDTARMANQTGAAPNTKYAEHGQWINLPSTLAQVMPMGEPFKANGAPLGFGNELAVQFDQETPEFAIVTMAGVQIIRRRRLVDVFAAMLKHGSTDEEGVEGDIKRFVRIYGRTETSATALAVACGQGVDVAENRVATITEPEVLEKARKAYIEHGGRPDYNANADSGDNPTNAVRASARHDGTAFYIARMVRSIWKQPIIKDIAKPGAGVELVSTISIDKLKKVQLSLTSLRDFLERNKSFIEGLAGPQAMTRASSRAEEIATQGEHQYMHGLLQLVNSISEGISFVLMLFDEKLEEILAILQDDSRRKVRELTFESLFTTATGKELAKELVKAIVNRNITNGSNVEAVAEGLRRRCGSFCSADDVVIFKALEQIKKAEEKGAQSEEARQLLNQSTKLFQKVAASLSFENVKLAVESYYRMAFYAGAIQLCLTVALEQDKSKRALAWMRDGKPTNDEREAVYNTRLQYYSLIFETIRQLEIDTRNEPEMVDGRTSLAMKRRSEAYEIIDHSDDVVFLTNLYDWYCNTGEGGFSQPQRLLEIDNPYVVEYLKKKAVEFRGHADLLWRYFAHHNDYLQAADVQLDIARSSFQGLTLEDRISYLSRARTNASTRQTILTDSRQNKQKLLREISDLLEIATVQDELLQRIRSEQRLNDESRARHIEILNGSILAVEELYNQYADAANYHDLCIVLYQVADHRNPADIRSSWSALIQQTSDEAPAFYGNTRAPWEAVGEKVRELGRRLHTSSATFPIPTLLPMLEKYAYEQPEQRRPPINWAVDVFLDLDIPHETLLPALEQLYYSNEHPFVGSKRKIIANKMVYLLQKWLEASERSGERVLFGSEENEETVRQCVDSLVRGDLEQGWRQAAEGIRQRLNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEP1</accession>
    <name>A0A9Q8LEP1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760389.1">
        <property type="nucleotide sequence ID" value="XM_047903671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEP1"/>
    <dbReference type="GeneID" id="71984401"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04523"/>
    <dbReference type="OMA" id="MSAEYKG"/>
    <dbReference type="OrthoDB" id="3359339at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="14902" checksum="2FED732C91488DD2" modified="2023-09-13" version="1">MSAEYKGQDPIDIAKQAERDLNTQQAKGNVKDQSSNLSDSARESGVNEDVISKFPGSTVQIGGQGAGDNRQIPLEEGGSINPGTGKPTKAGDFEGVGGPEDKARIYADQNGGDDAIRGNIRQGGETIRPGGGDSNASQGGTGGRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF68</accession>
    <name>A0A9Q8LF68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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            <end position="27"/>
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            <end position="106"/>
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            <begin position="160"/>
            <end position="180"/>
        </location>
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    </evidence>
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    </evidence>
    <sequence length="193" mass="21173" checksum="E9B34788F4AAB07C" modified="2023-09-13" version="1">MTRRIVYGISLWVFLGAVACTIAAMALPNWVTYTSPTDHDPIRVSYGLHKRCSSITGQCTKFPQYEDCHGENRGFCSAWRSTAFLMNFSVVLELAVVVAYVTVLVGGRGAREAGWKMIAGLLSAVAAGQIIAMALVAHLYETDSRFFVGWELDKSFVLCTVSWTVLVINALGVCSAAYFLPSEDDYEAIPDPR</sequence>
</entry>
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        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO16315.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="31044" checksum="9AD528FCC75CC5C5" modified="2023-09-13" version="1">MPLLSTWKLIKDYKNHQIVLKQVCDRRMALDKDKPDFMQHLMSRKGGISFSKEEIYSNAILITLGGAETTSNTLSGSVFMLATDPNVAAKVVEELHATFASEDKIDMRSASKLSYLNAVIRETLRYYPPGPNAMWRMTPPEGNTILGDWVPGNTVLSLHHRVIYRGEHSWRRPDEFLPERWLSEGKTSEFANDRRDGFYPFSYGPRSCLAMNLAYAEMRFILARLMWNFEIKIADKSRNWLEEQKAYLIWEKPGLHVHLTPRKMKEQS</sequence>
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    <accession>A0A9Q8LFS3</accession>
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            <end position="231"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <text evidence="2">Monomer.</text>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
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    </dbReference>
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        <property type="entry name" value="ADH-like_N"/>
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        <property type="entry name" value="ER"/>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF5">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="34"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="39989" checksum="19CD74AFA6EF5311" modified="2023-09-13" version="1">MLSTLRMSASRRLSQLAGQTRNASTMKEAVVGKGTKVTIQDVPIPKAGPHQVVTKVVFSGSNPKDWKRAEMPNQPAKNQGDDISGVVHEVGDNVSEFKPGDRVMAFHEMMKPGGSYAEYALSWEHTTAHLPENMSFEEGAAIPLASLTAAIGLFARLRLPEPWLPATKPTPLIIYGAASAVGSYAIQLAQRANIHPLICVAGKSRDHIEKYISREKGDTIIDYRKGPDAIVAAFQKVAQQHGKIEYAFDAVSEKGSYQNICKVLSTDGGRITNVLPGRKYDVPEGVVQSLTTVGRVHGVPDDLKDFGYVYFRYFAKGLQEGWFKPQPQEVRPGVLEGIQEALVSRKEGEAKAVKYVFRIEDTPGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGX6</accession>
    <name>A0A9Q8LGX6_PASFU</name>
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        <submittedName>
            <fullName evidence="4">Nitrogen assimilation transcription factor nit-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761651.1">
        <property type="nucleotide sequence ID" value="XM_047905103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGX6"/>
    <dbReference type="GeneID" id="71985833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05955"/>
    <dbReference type="OrthoDB" id="3648506at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
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        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="347" mass="38325" checksum="A036D7A33E094835" modified="2023-09-13" version="1">MEHPAIEDPGGRGAVLFASVEKSKRQAVVGACERCRSKKIKCDGQRPCSTCTKKNVRCIFTVEANESHQEARKRKFGEVSQAHNEAQDVLSAIANSDEKTALELFNGIRRGQSVAAILRDSRKGSESRAQDLDHQQRRKLFIMALVHSTAPLRDVIALGTAVLNGSIQLSLPTPDAYAPVRDTIVYLESIGQLLQVADPDITTLPLIGTYENNSLHHVIEDGIDHGPVVWVSATPWLNFNISDIAASHLISIFLHINNPFWRYVKQDLFVKAMRSGDRNSKYCSPLLVNSILALASQSSEIDESFSVPGDLLSRGDHFHKEALRLRALEEGHASLTNIQALMILSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGY3</accession>
    <name>A0A9Q8LGY3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGY3"/>
    <dbReference type="GeneID" id="71986463"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06585"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="60" mass="6978" checksum="DE7FE3E0CBF67A19" modified="2023-09-13" version="1">MKPSSKQGNKQREGEEDPRMQKQFAKEITVRRGRVKAWLDFFVQNNPLYADIVIDPDALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH04</accession>
    <name>A0A9Q8LH04_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH04"/>
    <dbReference type="GeneID" id="71985955"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06077"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="333" mass="39533" checksum="75ACA1F83A31B7C8" modified="2023-09-13" version="1">MAWTYADVLKFGPFKPHRKTFFDLSLEIRQQIYELLTPHNHEFKASNTYPYAPEDRYARILTLRRTTKHLRQEMDDWLSKTCGAYFYLHDEINLDPDEVLYAPPLALPYGRLRYVEIYIDCYNHYGSSRNYDECSHMWYEGDPSEGFTEGRVYEQRKQLQDVVTALKRFEDLPILYVRFRDEDNANHREMHRSRRYNQLGLTWCEAQHCLAAKSFANCHDAESYVPKYILDPLLELPVCAKVIVQPLHLTDHEGRSMRSRDIPQADQADSGCRAQEYVNTPCTAYERWIEGERSEAFESCWRDFGSDWQRGEQDRLEKLETLKQAMPSARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH32</accession>
    <name>A0A9Q8LH32_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(A)-specific ribonuclease PARN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761643.1">
        <property type="nucleotide sequence ID" value="XM_047905284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH32"/>
    <dbReference type="GeneID" id="71986014"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06136"/>
    <dbReference type="OrthoDB" id="1432093at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990431">
        <property type="term" value="P:priRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990432">
        <property type="term" value="P:siRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="606"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="704" mass="78524" checksum="5D1737959B047308" modified="2023-09-13" version="1">MHTVAARAVAATPSTCGLPRIAVCITARSSFIHSLTHAPLSRAHPRQRRQVRVCSRSYASASSASPSSPAVSLSSSALGWLRRLISNWNLTTLATCTRTSSSDPTTNIAKLSSPITTTKMDVDKVSFYPLLLDIITDISEAHFVAIDLELSGVPSKGSWGKDSGKPTIQQRYLEIKEAAERYQILQIGITCVDQNVHDGKYTLKPYNFDLSPVISERGLDVERIFSFQSGAAEFLLGVNFDIGRPFTMGVPYLSRAEAKVAREKFAMRQDKTSMADIHIKPTETESLAFLERVRGEINAWVKSRNMDTPAYLNIAPVGYDTVKDGQRQAEELSRFEKRLVHQLVRAEFPELVTVSKKGFIQIVRFNKEREDRIAADRRRELEERIGRQKGFRWIIEALHGSNISNLDLRECAKDSVTGEPIFADMDDYKAQFNRAQGILRGNPKVIVGHNCFLDMVYIYRTFIGELPDTVEEFQRALHKLWPVVVDTKYMTTHNCGDISPISSLEQIAEQLSAQTTPILDTDKQHTKYNTMDAFHEAGFDSFLTAQVAVRLSAKLEREGTYIDVEDRRNSAAPTDITNGVANMKLTGNALFELQKEQKANGNVDASEAGGFTPSVPGAQWKRVGDPTLEPTSKDDLFEYDPTDLKHRFTKQDLTIPGGMPRFGSDFWRVYGNKFRVFGTQEGVCALDDSIESPIASDEDGGVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI8</accession>
    <name>A0A9Q8LHI8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761640.1">
        <property type="nucleotide sequence ID" value="XM_047905286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHI8"/>
    <dbReference type="GeneID" id="71986016"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06138"/>
    <dbReference type="OrthoDB" id="3921745at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="25471" checksum="05B8EB0510C08B71" modified="2023-09-13" version="1">MPLYTGTSMEARTDSQQQSAVDAYTMRRHPERMGRIPISMLLTPSPESPPCRPAAHPHRAESHSSSSSTFDSRRGSSITTSSFGKSPTLDTILNGSTPRNPYSSTRPYGSPEMDPYPLPPETLNLGRRPRAPRPSYSEEQKFFIMYTRIVRDLSWPEIEDEFYRFFGSRSKGGLTSVYYRVRRDWGMLEVLKSGANSYAADCKEVERRAMNFSAEFLGQIGYLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHS3</accession>
    <name>A0A9Q8LHS3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762032.1">
        <property type="nucleotide sequence ID" value="XM_047905665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHS3"/>
    <dbReference type="GeneID" id="71986395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06517"/>
    <dbReference type="OMA" id="CPELWNS"/>
    <dbReference type="OrthoDB" id="5322539at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF6">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="585" mass="63930" checksum="3682B90E3AD1670E" modified="2023-09-13" version="1">MAHLSDSSSAKGSYAKVSRDHIPEQHPRKHHDSRNGRGKSWKAPATMLSALTLGLVLALAQHFTYVSLDGKPVASISVSQAWVSRISTGLAFAVKVAFTICVGAAFIQHQWMRLRESPFKVVDVDTITSALGNLFCLFESTVWLRYPVLTLMAVVSWILPLSAVVTPGALSVEGVQNVTTTPMQVAQPVYNFTNYGMRASGGGTYEISEDARLTRLLTNTASAQTPVQLASSFQNQTYGIHFDGPALRCSSANDSVIRNLTGRYGFTSGPGDFMNFAAWVPGGDPSDYAQSSSTSSVSARTVDVASPDAARIFVMTNIGGWNNTLNFSTSYNTTRSATVVNVTECLLYNATYEVEFSFRYPNQTRNVEITKWINPVSSGVFGPGGEGAPFSQKDPEELSYLAMMSALGRLLLGQSTRSHYGYIIRTRTNWDMLSIDWASGQAVEVGLEQLFQNFTLSLLSDSGLIKNSTTADQVPVQIETWPITYVYRRADLFIPYGLSLLAALLCSALGMRAFLVNDASYSNIYSTYLRATNNARIDRYIDDSDTGHDPLPKSFGAVTINLTEHKVDYDQLDTMGIGDNRSQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI58</accession>
    <name>A0A9Q8LI58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762212.1">
        <property type="nucleotide sequence ID" value="XM_047905616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI58"/>
    <dbReference type="GeneID" id="71986346"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06468"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="467" mass="51687" checksum="E258CFAB6F2F7F7B" modified="2023-09-13" version="1">MAIIYLSIHLLYHGEHVEIVSKVISSYATATHIPAPVPTSSPFFPDCCHEGHSPSPDWVTAESQPASTEFGGIGFPVSASDPASSDEKVDWEQLLDAIDELLALAQRGEGFSEHVSYKQLGQYKGQVFRAERAWQLSNRGLLAQEQVEVGMAKVFQDLASFTNLDWPALSVALRAGDYSTISVSCPDTVGTTRPTPHGPVVPLKGHADAPPGSTKSAPNIWCFDRSLGLPHTLHIHPDAKVPFGCSPMLPIRGKGLLKDMESYSWDLRNQIKDLKDFLARLIRNSAEEMEIGRSDLLRLISFRLMSSIVREETKKQVRLDNLKLELLDILGPGVEDQYVFSTPEVTADAPPREHSEPAAIPTLESGLALKQTETTSKGHSGWTRCGLKIMPHTWRCPKRRSLPPKWMSYLVQPRPMAQGGFEWRTWRLQSAYRAVAAAGDEPGKGSRRAGSTLNNLRLKRMIEQQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK1</accession>
    <name>A0A9Q8LIK1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762657.1">
        <property type="nucleotide sequence ID" value="XM_047904608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK1"/>
    <dbReference type="GeneID" id="71985338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05460"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39991" checksum="01542E70E485E2FA" modified="2023-09-13" version="1">MLLYVQRPCMCLIRKWPSAAFPKQRLFEIFTTATPHNTLVRGPPHSFATDIHSFQGHSLSFDTLFQSTTDSSKMLFNRALVGVLFAAACSAHMMLDYPAPFNASHNPHRKTAADPYLEFPYDKAGPNARWMYPCRGYEKLLGTPDGAPTATWEAGAIANFNISGIGNHFGGSCQVGFSTDGGTNFHIATSYMGNCPHRDNGNGPDGQNFEFKVPGDIEPGIHLFSWIWYNREQELNMNCAAVEITSSSPQQAAPLPPAGSLTTLTIFTTQTAVVPVVTAGVAPPNYDKSTRDSSEAIAFQDRPLMFVADDGNDCFTPRSTAELKYPEPGPDVVLGDGAYPLELPTGQCSQEQMLAKQAFKGDRTAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIS2</accession>
    <name>A0A9Q8LIS2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761729.1">
        <property type="nucleotide sequence ID" value="XM_047905072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIS2"/>
    <dbReference type="GeneID" id="71985802"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05924"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="2">
        <location>
            <begin position="162"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27626" checksum="06ACF10CE0B91622" modified="2023-09-13" version="1">MCGNCMDICCVGIFMSCMGCCYRHEGDLEVLPNGRPGGKSPAPKTTVTKPLQRKKETATNLKDLRNTWKNPFQQPRKTHPAKLFPLLTKDTLSSTPLTASQQTAQTRLRELFSGETEAFRQLDTLLQAALQLDTLLFNSALRDHIAITVEEFRATPLWRDKLVKGRCIVPPGPLKRFHKVQIQLNNTLLVYGSREEVLGTLVHEMLHAYLGLVKGWRHREGDIMALAEGCVRRVGVEGLRVEHLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ30</accession>
    <name>A0A9Q8LJ30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762676.1">
        <property type="nucleotide sequence ID" value="XM_047905020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ30"/>
    <dbReference type="GeneID" id="71985750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05872"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040243690" evidence="1">
        <location>
            <begin position="26"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="30172" checksum="914A54B9684D3E14" modified="2023-09-13" version="1">MLLLHGPTIVLYLCVFLLLTQLFHGHPDRPGYYSVVTSPESLPTKAPNTIEDLQTILDDVASLRLNVLYFTEDIGTRLMSIEALLSSLVAQGASLSAPSIIPNTYPIDVPLPYETPPPYPTPHNGSYHGTGITAGPTGTGYSYWQPTPSPTSSDAWDSQVTSNIAVHHRIFDNSAPLSNLCDDSNVNIVILDFLFTFANLTEGWPDMWSGKKILLRLGQAVPGTNFDVAEAELLAEQMWNLFGLKSPDYNGPRPIGDDVTVDGFEMTLNIDNPDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJL6</accession>
    <name>A0A9Q8LJL6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Probable electron transfer flavoprotein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05871</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </cofactor>
        <text evidence="7">Binds 1 AMP per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762224.1">
        <property type="nucleotide sequence ID" value="XM_047905019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJL6"/>
    <dbReference type="GeneID" id="71985749"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05871"/>
    <dbReference type="OMA" id="EINQPRI"/>
    <dbReference type="OrthoDB" id="276685at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000011">
        <property type="entry name" value="Electron transfer flavoprotein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00070315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="27944" checksum="A86908E364158689" modified="2023-09-13" version="1">MATKLRILVPVKRVIDYAVKPRVNKAQTDVERNVKHSMNPFDELSIEEAVRMREKKKPVEDILAFSAGPAKSQDIIRTAMAMGADRGIHVVEEKTELEPLGVAKLLQKVVEQEDRNLVILGKQSIDDDANQTGQMLAGLLNWPQATSASQVEIDGDHVTVTREVDGGVETLKTKLPMIITTDLRLNEPRYASLPNIMKAKKKPLEKKTMADYGIDATKRLKHVKVAEPAPREGGGKVEDVDGLISKLKELGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LKN6</accession>
    <name>A0A9Q8LKN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762884.1">
        <property type="nucleotide sequence ID" value="XM_047906150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LKN6"/>
    <dbReference type="GeneID" id="71986880"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07002"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="20269" checksum="175B3B3B34EBFC47" modified="2023-09-13" version="1">MSLLCGDPSSAIVGTFHLEPLLWLESAFAHRYRISRRIANGRVTLPFLEVSPSTTSSDIASIIFGNSKIGIFGAKIMATTGARCEERTRKWSHPGASWRQIKLFRDYEPGRIIIEQSFRIQPYRDRDRVPGQYKVEYIIDDTWTLGEPWECYTDSCIKDRSEHETLMLRQQGGKGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2K7</accession>
    <name>A0A9Q8P2K7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755182.1">
        <property type="nucleotide sequence ID" value="XM_047901322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2K7"/>
    <dbReference type="GeneID" id="71982052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02174"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="79" mass="8369" checksum="FEB66F22E0B4679E" modified="2023-09-13" version="1">MSLQTSSVAADGAFTITWLNVEQTPEQASDLPHPTDAKISKVAKVDNHYGYPCTASADAGFGRSQTADAVRSDKSVRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P428</accession>
    <name>A0A9Q8P428_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CUE domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756904.1">
        <property type="nucleotide sequence ID" value="XM_047900356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P428"/>
    <dbReference type="GeneID" id="71981086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01208"/>
    <dbReference type="OMA" id="RRSADHN"/>
    <dbReference type="OrthoDB" id="9942608at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14372">
        <property type="entry name" value="CUE_Cue5p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000064">
        <property type="entry name" value="Similar to CUE domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041807">
        <property type="entry name" value="Cue5/Don1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="78"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="49583" checksum="6C526A01592AE957" modified="2023-09-13" version="1">MAADRSPVSPIKPDEESATTREEIDMDDNEQETGTVSPHGHETPTKPSAKAPSPRPRVSFQEGHEEIPPTKPPRPLTPNQQAEHTLIEAFPTIDAKVVKAVLTASGGKVEPAFNALLGMSDPDFHAEEAAPPQPPRPAQRQPMSQLEADEAYARQLAEQYSSGGQSTQNRYNQREPGRRGPNQQRPDYDDDDRERSFFDDDLPEIGKNIQQGFLETQKRVNSWITQFKKKIDGEEEEDLYDATPSNTRQNTGLSGRQNFGASQSEQLYGIRRSAEQQRRSTEAQRYDADPHEFDHEEFERLELRDDEGPPAQPPRTSSRTKANPDLFKSGVKPPQSGPVDEVDAAERRQPGKEASDKDKKWQPLTSVAPHPEDDNDPFSLGDDDDDKDKSEDLRKEDTERLKESARTSISAGNTSNNVLKPQESETNGGVRNKEAEEILSGKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P446</accession>
    <name>A0A9Q8P446_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756964.1">
        <property type="nucleotide sequence ID" value="XM_047900416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P446"/>
    <dbReference type="GeneID" id="71981146"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01268"/>
    <dbReference type="OMA" id="WEDMQHL"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
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        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="43801" checksum="F0106064DF6AA892" modified="2023-09-13" version="1">MAEAPIVLDGGTGFLKAGYAGQNFPDHQYPSIVGRPILRTEEQAPGDIQLKDIMCGDEAAAARSMLQITYPMENGIVKRWEDMQHLWDYTFFEKMRIDPAGRKILLTEPPMNPLKNREQMCEVMFERYNFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESTVLNHLTRRLDVAGRDVTRNLISLLLRRGYALNRTADFETVRAIKEKLCYVSYDLALDQRLSEDTTVLVESYTLPDGRVIRVGSERFEAPECLFQPHLVDVEQPGIAEFLFNTIQAADVDIRSSLYKAIVLSGGSSMYPGLPSRMEKEIKQLWLTKVLGGNPERLNKFKVRIEDPPRRRHMVFLGGAVLANIMADKEGMWVSKQEWEEQGSQALKKLGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P447</accession>
    <name>A0A9Q8P447_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756802.1">
        <property type="nucleotide sequence ID" value="XM_047899939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P447"/>
    <dbReference type="GeneID" id="71980669"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00791"/>
    <dbReference type="OMA" id="EMAYAIG"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="31"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="415" mass="44579" checksum="02DE305015994C7E" modified="2023-09-13" version="1">MPRREGHENAALFTISICLIFVACAGLLRAWIRKSAYGRDDAVIAAATLLSLGQFGSSYAAVEEGLGKQWSGLNALSMSGDLRKLNEASLASIALFFVALYLSKCAMLAFLSRITKTPTQILLYHTLNGLVALIGVLSIIVVLAGCPSGSGYYWAFNRNTATCPSQGARWQAVTALDLLTELLLLILPVHLVWNLHMPMKKKAMILVAFWVRLPALCFCLARTWYTLQLEKPGADVGLDSAFVLIWMEVEMAYAIGSSTLSAMKSYTDSYNTGFGMGFARGKGEGSYGLSNVSGSSGQSSRGEKAKSASPTTSRTDRSAKTTPDGCRGDEPPMPPATAHGWHVADPPPLKLRPDTTGVTSYTSVSAEPHNDVSQWRSGSSLGSDSSGDDMVILRETAYEVHHDEAPMLPIAVTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P481</accession>
    <name>A0A9Q8P481_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757176.1">
        <property type="nucleotide sequence ID" value="XM_047900057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P481"/>
    <dbReference type="GeneID" id="71980787"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00909"/>
    <dbReference type="OMA" id="EFWILLK"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="521" mass="56797" checksum="7B6AD100803DE1BF" modified="2023-09-13" version="1">MEGIQDDFKGAHTWLPRFLKPNRAKRASTSKPADETTSLLPEPEDEEPFESDISEIEDAPWHKRILPEFWILFKGSIPVILAYTLQNSLQTISVLIVGRVSPEALAVAAFSYMFAMATAWLIGMGGTTAIDTLASASFTGSKNKHDLGIILQRAFVVLTVFYIPVAVLWLCSEPVFKSLGQEDYIARDSAQFLSMLIPGGFGYIYFECMKKYLQAQQIMRPGTYVLLITSPFNAGLNYLFIYTFKLGLMGAPLATGISYWLSFLLLLAYCRFVAGYECWGGLDRRCFNNILSFARIAILGVVHVGTEWWAFEIVAIVAGQLGTIPLAAQSVIMTADQVLNTIPFGVGVATSSRIGNLLGSKSAKGAALSANTAAVLSMVLGAIVLAILMATKNNFARLFNDDDQVVRLTAEVLPYVALFQIADGLNGSCGGALRGMGRQHVGAIVNVVSYYCGALPPGIYLAKQGGWGLAGLWVGQCIALYLVGIIEWAVVAFSNWEKQVENAFRRMDHDDVTEQGDGDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4L8</accession>
    <name>A0A9Q8P4L8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proteasome subunit alpha type-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00692</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757238.1">
        <property type="nucleotide sequence ID" value="XM_047899840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4L8"/>
    <dbReference type="GeneID" id="71980570"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00692"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000009">
        <property type="entry name" value="Proteasome subunit alpha type-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 7 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="9">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="705" mass="79515" checksum="6378B2E77272963A" modified="2023-09-13" version="1">MSRRYDSRTTIFSPEGRLYQVEYALEAISHAGTALGILANDGIVLAAERKVTSKLLEQDTSAEKLYILNDNMICAVAGMTADANILINYARQAAQRYLLTYNADIPCEQLVRRLCDLKQGYTQHGGLRPFGVSFIYAGWDNQRQFQLYQSNPSGNYTGWKATSVGANNASAQSLLKQDYNEHCNLKQACELAVKVLSKTMDSTKLSSEKIEFATVGKTKSGTIYHHLWTAEEIDTLLKEHGLAKASDDEEPEAGLSEQTYLKFSNHLRTDILILTTDFSAKTTLMATRNRKPRDKPNGATNAADATRSESPEWMRELTTAKATHPLAGSSSEALDLNSVRATETPDIQFIRPELHQFPVVLYHCSSPAATCITIKSWLETNLGSNIDTTLHIVRMEKQYLHLMSERHAPGTLVLLDHAAYIPANDGDVPVTILALVMEQDKYVRFFYSILPFTPLLHVLEDTSNDSGQPFISFKKSVGAYTESKHRVTDEGGENRPDRHCRLFVFFRETFERALKVPDHPDFVSAEAMTDYAPDIKDPDTALARLESDETLWKEYPSALDKIDMEERTEDGVTITPSDDRYIALLHPAERELAFQMELKASAYLLIKRNFFATFYTEIQRNEKKPGKPLRSDHASSQWLEREYGWVNRKARRLVVGWRILGLLDESRVMQWINEGGILAVSMQKREDDEENESNDQAGKVVARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5F3</accession>
    <name>A0A9Q8P5F3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758078.1">
        <property type="nucleotide sequence ID" value="XM_047902468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5F3"/>
    <dbReference type="GeneID" id="71983198"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03320"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="36395" checksum="45FC421FAC9499E3" modified="2023-09-13" version="1">MCCRCATFSFSMYTQTSLPRPFLQSHPGTAIKMAATVGASPDLKMQGFGPDCAVASENAPAPAVAADKADTKPKTDRPRKRPLSPPHSSSSWQASDSQPAPKRGRGRPRIHPLHHTIEVRARQKRADIADGDMTARDGARAAVRHTARQPRSMSDPYKVLGLKCCETDPALIHAAYIKAQMSCGDMLPGPLQLSDDPDSAGHQRLTMVSDANVILESRRMKTLLDKCLNHHYKKHTASAIDILDIAISLVRSPPTEQEVEQAYIDRMAEWSGLEKVAGVVIRMFKAARETVLRDLKQAQEEQEKQSRRALVERRDSVMSDADALGDEVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P667</accession>
    <name>A0A9Q8P667_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08063</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759094.1">
        <property type="nucleotide sequence ID" value="XM_047907211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P667"/>
    <dbReference type="GeneID" id="71987941"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08063"/>
    <dbReference type="OrthoDB" id="44736at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="568" mass="62032" checksum="3540CE47DBA98E7F" modified="2023-09-13" version="1">MMSHTKGRRISEDSEDLLELDAYDGRDYTGPTAHSTDRLEMEPFKQGGQANGEAQDYYQGGGQQPQYGQAPDQQQQYGGQQQQYMPNPPSYSQNYGSGGKQDFTQTFKIDKPKWNDLWAGILFIAVFLGFVAISGLTIAGYAGNKGFNGGGIYGSSNDFSLNTNTIVLFCFILAAALILGSAYVSLARIFTKQFIWISGNLNIVLSLATAAYYFYRRAWVGGALFLLLGVFTIFCFITWIKRIPFSVLMFQTAVDVSRKVGHVYLVSFLGGLVAAAFSAWFAVTLVAVYIRFEPGPNPSCNAAAGGSGGCSSATVIGLLVYITFAGYWITEWLKNTIHTTISGVYGSWYFSPRAPAKAPTRGAARRALTYSFGSICLGSLLVAILDLLRFACSVARNDMQSGNLVADCAFCVLQCILGLVQWALEFVNRYAFSYMSLYGKAYFASAKDTWKMIKDRGIDALINECLVGPVLSMGCLFVAVSCALISYVYLEVTSPAYNEGGKFTAVVVFYAFAIGLQVAGCFVVPLNSGIDTIFVAAAWDPEVMMRTHAQLHDRMVTIYPHVQQAIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6T8</accession>
    <name>A0A9Q8P6T8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sphingomyelinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759548.1">
        <property type="nucleotide sequence ID" value="XM_047907536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6T8"/>
    <dbReference type="GeneID" id="71988266"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08388"/>
    <dbReference type="OMA" id="THCSEER"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040282739" evidence="1">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="31477" checksum="F542C024D3069D50" modified="2023-09-13" version="1">MHLSHLTTLAPLLSSALAASGSFNVLSFNVAVLPEFINDNGIKGGKENAATMIGQRFAQYAFDVIQVQEDFDYHEELYAADNHPFRTKTFGGVPFGSGLNTLANFGWSDYRRITWDDCYIDKGDCLTPKGFTFMRMNPVQGVEIDFYNLHADAGSGNDDEAARRSNIQQVADYIGANSAGRAVVVFGDTNTLYSRPTDNVRIFGGQNGLTDAWVQFQYGGVIPGGVPECPEPTTDNSCETLDKVLYRRGSAVTLSATAFDYVTDLFLQADGSILSDHNAVLVDFAQSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7N2</accession>
    <name>A0A9Q8P7N2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05260</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760582.1">
        <property type="nucleotide sequence ID" value="XM_047904408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7N2"/>
    <dbReference type="GeneID" id="71985138"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05260"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040204527" evidence="8">
        <location>
            <begin position="20"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="78"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="45619" checksum="F3F8694FA7F6F4CE" modified="2023-09-13" version="1">MKLSTSQILFASVAPLVNAFPAALLERAANDAAMQADADKIAQLLSRRQQGADAAKALFEPVPVFDAQKQLIDVSKGSGHEYVAPGPGDLRGPCPGLNAFANHGFLPHNGYATVSQYIEATETVVGMGPILAGFLSILGGAIDGDLLSWSLGGTPTLAQGGLTGVLGHGLVGSHNKYEGDSSPTRGDLYQAGDNYKTVTSQFQDMINFSPNGVATIESLTNFRSHRFDQQIATNPYFFNGPFTGVLVQPAAYAFIYRFMANHSAENTEGELTHSTLQSWFGVEGTDGNYNAVQGTERIPENWYRRPQAYPYEVTYFLADVINAALLHPKFLDIGGNTGTVNTFAGVNLENLTGGVFNVLDLLKGNNLGCFVFQLSSQAKPDILTGPLNALLGVVGGLVSQLGCRQLKAIDNKQLEAFPGYSRNPVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7P3</accession>
    <name>A0A9Q8P7P3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760612.1">
        <property type="nucleotide sequence ID" value="XM_047904330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7P3"/>
    <dbReference type="GeneID" id="71985060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05182"/>
    <dbReference type="OrthoDB" id="10502800at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040303796" evidence="2">
        <location>
            <begin position="22"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="36423" checksum="6EDECA46FC821DBB" modified="2023-09-13" version="1">MLISTFVTALSGLAASMSTSAGQWKPVSTYTPFVRSGATPSITHPPYTRTDAPVLTTRVTTIVETVGSEPTTMATGPAKPKGSEYYTTTVAYGTYGVITVSGTPPAPPSFKESLSLTYHPAAATSNRTAPATPTSTNPLANLDPNRPTKGLVFAIQRYADANCDQPIGPRFAYDGSQDNSCFFSHGSCRGSCGYLSQDTPSSPEVWKHAKQQLSAKKLEQHDFASWNYRLVSWDDVWNKNNKWKPAYGHMRHKHKKWMFPESNNEGTAVCDAVFWEQRDCRDNSPRPESGQVMRWQPRNLREDEGRCMNGFKNGRGVPAMAASFRIRCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P865</accession>
    <name>A0A9Q8P865_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="5">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_05115</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="5"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P865"/>
    <dbReference type="GeneID" id="71984993"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05115"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:pyridoxal phosphate binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:threonine deaminase activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:gluconeogenesis"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:isoleucine biosynthetic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000040">
        <property type="entry name" value="L-serine dehydratase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="11">
        <location>
            <begin position="15"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO16768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="41567" checksum="B93211FC78E743B2" modified="2023-09-13" version="1">MGAQRLKIPPQQRPWRQTPLIESVNLSKAAGCRIFLKLDNLQPSGSFKSRGLGNLVLKSMERAEDPDKVHFFSNSGGNAALGCISAGKFVGRPVTVVTPMSTKPHMISKLYAAGAKQVIQYGPGIKEAGDYMRQVVIPKAVERGEEPIYVSPFDHPDIWDGHSTMVDEMQQQFCDLGEDAPDWVICSSGGGGLFIGLMQGIEDQGPTWDKTKVLTCGTHGADALTTSLAKGENTTLPKITSIATSLGVARVSDRAFELAVEGRASGKVKNTVLTDAEAAMGCWRFAEDERLLVEPACGVNIALCYGNRLKKALGRPVRPDEKVVIVVCGGSNVSTAIVEGWREVYGDVDCVNGYRRDSLVASDGIAPDWIVPMGGHASGHHRLNEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K7</accession>
    <name>A0A9Q8P9K7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06157</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762412.1">
        <property type="nucleotide sequence ID" value="XM_047905305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K7"/>
    <dbReference type="GeneID" id="71986035"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06157"/>
    <dbReference type="OrthoDB" id="167718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="180"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="277"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="536" mass="60600" checksum="B49607B4FA53289B" modified="2023-09-13" version="1">MHTYRSQASTPYQAQRNRQFTMDGKNRNCPKCKHEVRSKMKGQPWPLLLCEACLNKKKPKNYAKQQDRIERRLKGGIPLSLGLLKFQAEVAPAKPKNPTLGAEDLPADVRTWLDQVSLSVERLEALPAPYGHALLALNSTDTLQTTSRASESSTYIKREDSAESEDTKLPRAARGQGSNKTLFIGGLHREVKKTMLAWFFKDYVHDIPFVRHNWKVKGRGKAVEWALVEMDTPSEAARAIRELDGKELLDCKVSVHFHTPRASVKPFDPQVYTETGRTLYIRGIEPDVTEDMLLTFMDDFEARVHMIKNDYAIVEVSSSAEAQRAIDWLDKQRILKRLLRVQINRNKWHEPVPDILTGAPRALTPIYKLQGDDEQKFLSTFDQDEVKQEEPRQSEYFAPQAYFSGRAAISTEHPPVKRLGYGIKREGDVDMSDVDSMSQVSDAPSTGDPPREIGVGAGGGGEWIAGVLSEILQMEMASRPSSWLDVSMSVQRELQHQLMRDITEGDPREGTPISVPLLELLDARVEELRQIQESQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Y8</accession>
    <name>A0A9Q8P9Y8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762969.1">
        <property type="nucleotide sequence ID" value="XM_047905936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Y8"/>
    <dbReference type="GeneID" id="71986666"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06788"/>
    <dbReference type="OrthoDB" id="5410873at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="36428" checksum="C892D07D266230A3" modified="2023-09-13" version="1">MSRMATADLSGLPPELLLRITDCLNATELLPLSATNWSFRDCLVPVIFSTLRVTNRRDEAKVALDLAKKHSQHITTLSFEGYASPTENDRATRGRSWGPKGTSTLPAATRNLLTGLHLPKFRTARIRFAYDYASEDWATDPSTNGRTAGFHDFDASEFDKQIAQQEPKWKWRALMAETWLALAQNKQIENLETIDLPPRGTTAFINPAFQDFLRRLKRVTLSIWGSSKGAGWRVQTFPGYIAFLSCMHNWFFKQLETTTTLALSASLDGLPGLTGTLLSGIALQRDALPLVSTLELSLTAINPNLIAFISGHAQASEVSASTGASARPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB44</accession>
    <name>A0A9Q8PB44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AB hydrolase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763587.1">
        <property type="nucleotide sequence ID" value="XM_047906066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB44"/>
    <dbReference type="GeneID" id="71986796"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06918"/>
    <dbReference type="OMA" id="GVYLHIH"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="99"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="37999" checksum="533BA2935CF99C4B" modified="2023-09-13" version="1">MPLESDLKLDYSKFDPANITQKTKDFNDGLMKVMNNGPKWYEVGAEKYRQMRWNGETPIPKPVILEAGKNGKIPSREVGRDIPTRTFEPEHGKSKGLFLHIHGGGWVLQSEHFQDLMLQRYATSSSLTVISIGYRLAPEDPYPAGNEDCFDAAEYLVDNAEKEYGLTLMFMGGDSAGAHLSVLTCYQLLETRPGFAFTGLVLNFGAYDISGFLPQAWHFDLPLVLDVDIMIKYTDAYLPNMTQEQKRDPMISPLFMNLNKLKLPPALFTCGTLDPLLDDSVLMSAKWAMSGAESISKIYPGAPHGFSFFPVGGTETTEQGLNDIAMFMNERIAASVRQSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBE5</accession>
    <name>A0A9Q8PBE5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763701.1">
        <property type="nucleotide sequence ID" value="XM_047905860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBE5"/>
    <dbReference type="GeneID" id="71986590"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06712"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="127" mass="14706" checksum="785978820AC00ECA" modified="2023-09-13" version="1">MDDVLEIGNEFTNPPIIRAARHADIKYLQQAIERFKVDTTRWKHCFDPNYQCDEYFQAHSATPLIEAARNGLEQHVALQLEAGAKPDKVQRRYMGKPIAPMPMVSLSGQAFINRKRADKRARFWSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBF1</accession>
    <name>A0A9Q8PBF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763750.1">
        <property type="nucleotide sequence ID" value="XM_047906510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBF1"/>
    <dbReference type="GeneID" id="71987240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07362"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="222" mass="24317" checksum="854A586675E9ACC5" modified="2023-09-13" version="1">MSTIAQANHPHQHKPSPKRSSLSPRLYTETRGDAYTRALGRNPQVADEDEDLPVWLNYLLNIVLNTALLLISTALLARIATIVGDQTATVAELVKNGACLVPELNSWHITNNTIISPLRLHTIAALYLLSIPLLASRSADGYSVTFQDFRSGMAVAAFVSVVGLGVWWVLVMGTLFVRDVVACGGAVREWVGRALVNETEVMREQYELVKSARARLVRVDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCH9</accession>
    <name>A0A9Q8PCH9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GCR1-dependent translation factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10149</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764314.1">
        <property type="nucleotide sequence ID" value="XM_047909297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCH9"/>
    <dbReference type="GeneID" id="71990027"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10149"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040337372" evidence="8">
        <location>
            <begin position="21"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="568" mass="60870" checksum="29D48B94CEE836D4" modified="2023-09-13" version="1">MRIRRASPLLLLLAPSLAAAADVPLSKEGVEVLNNDEMLALNHPPQSAKQKPLDPTEANPDAKTTSTARPYKGTEDAPVDGLDGKPHAGPWVDRKPDSAATTTSKSLPTSMKEFEKTSAKERWKLEDIPEKNDGVMDDEKRIAPKKGTTGTEGGISEKTRKEQAGAKENTPQKPKAAPPLPQSEEEHIEKGERKTSAKDAVGSKDAVTGEYVEGSKKGDGYGEAGYGMEKPKDLPEKPHNIPHPNPGVATSDLGPPVNPDGGRDKWLVDTMPDTEGKTNSRSAKPKSDSSSSPTPVTSKGDESWHEWFHSFVLSFAMIIFSEIGDKTFLVAALMAMRHARLLVFSAALAALIAMTVLSAVLGHAFPTLLPKKFTTFAAAVLFFVFGAKSLREGLAMPKDAGMGDEMREVEEELEEEEHKMRRKSHSKMSPHELESGRGRSTSLNKGGIPDSPPMSRSPSPSRRKSTGLAGLQNLLSLVLSPAWVSTFVMTFLGEWGDRSQIATIAMAAGQDYWLVTIGAIAGHACCTGMAVLGGKALAGKVSMRVVTIGGAIAFLVFGVIYLIECIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDI3</accession>
    <name>A0A9Q8PDI3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764812.1">
        <property type="nucleotide sequence ID" value="XM_047909341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDI3"/>
    <dbReference type="GeneID" id="71990071"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10193"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="25157" checksum="4089A0B0C86D4629" modified="2023-09-13" version="1">METRDRTLRDTALAENALLQYGKSDVSGLLYRDSAAFRAYIKLQRLPTGAPAFDLDAQGYPTIHQGECVCRMKSSASDSDTLCGALYGGKAHLVRHVHRDHGLKSECPSGRKRTTGRGEACKFYLMVMEHEADRAEGEEKERIKVVVKQEPGTDLMPQPLTRGPTARGGRKRALSEGDISMATSEAQTRTLELEIEKTDLHIQRTNLQIKKVELQQRLHKRRGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV6</accession>
    <name>A0A9Q8PDV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765006.1">
        <property type="nucleotide sequence ID" value="XM_047910140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV6"/>
    <dbReference type="GeneID" id="71990870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10992"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="222" mass="24719" checksum="E5590722E7F28DB9" modified="2023-09-13" version="1">MHHASDGATDIHISIIDTKYLAPENALMSTMTADRICDYIFPFRDEFFAFGTISGPAHHAIPCAAIKDRLPTFLLENEEDDIIYPVCAGWEECIEDAGAIAKLLPPRVQAAFAAHLLVMHDEKHPAGCERRNEEIVAFLSTFDDGIMTSLAVDDTIMQPGFAATHGYNEADRAAALLRGLVYNQLGQESVEALRRTAKAPDETPFEREQRWHREECKDEDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFM3</accession>
    <name>A0A9Q8PFM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765911.1">
        <property type="nucleotide sequence ID" value="XM_047908069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFM3"/>
    <dbReference type="GeneID" id="71988799"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08921"/>
    <dbReference type="OrthoDB" id="3650808at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="243" mass="27369" checksum="D4115D06CE749293" modified="2023-09-13" version="1">MTTATLDTNCKKIFPFFRLPRELRDSIYEECDGSQDVSLSGPKDDHLQAWVEGGFRINLLLVSKQFSDEYQERQRGNATLMVDMTATSRSYTFKAEALDELRARAARPPTLLSGPRRLDDIEARLPALPGCVSYNIETSLVALSILFRQMRKHGDLPKRIKVYIQNVGIDGLMLPTLQNFYDQNGLLTVQGGRMIAFSSVCGEVNAEIYSQLRDESNMYWQGDKDGVSLIGTWTTEDGWKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ5</accession>
    <name>A0A9Q8PFQ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09547</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766017.1">
        <property type="nucleotide sequence ID" value="XM_047908695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ5"/>
    <dbReference type="GeneID" id="71989425"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09547"/>
    <dbReference type="OMA" id="HIKSFCT"/>
    <dbReference type="OrthoDB" id="406544at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16106" checksum="346EBB443B22CF36" modified="2023-09-13" version="1">MAAANILRRGSGLCQSVKFSITGTPARHIQCNCLNCQKSSGSAFLTNILFKRDQYKVESGAEHIKVFKDTSTDSGGTLERSFCSNCGSPLHIRNVSNPKMSGNIVVCGGTIDENYKNFKPQSELFPHRRHAWVPEVQKAKKEASKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG78</accession>
    <name>A0A9Q8PG78_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766400.1">
        <property type="nucleotide sequence ID" value="XM_047908434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG78"/>
    <dbReference type="GeneID" id="71989164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09286"/>
    <dbReference type="OMA" id="MRHGQGY"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="28142" checksum="309651C21D75DAFE" modified="2023-09-13" version="1">MPPILHIMRHGQGYHSHDVTKDGHLLHDPSLTEKGKQQCIDRCKDFDRHDKIELLLASPLRRAIQTCQLAFAPCVERGLVIIALPTAEEVSDAPSDTGSPVEDLIKEFGDEKVDFDHLKHGWYKHEGEFATDAKACNARALKLRKWIQARPEKEVALVSHGFFNHFTTGEVDDEGEQTTPWWNEAELRTYQFRDGDDEAAMIYETDESLAKRGMHLQGGADRGEVKVNQPSRRGTLPNLSFQNQEEGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGK7</accession>
    <name>A0A9Q8PGK7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGK7"/>
    <dbReference type="OrthoDB" id="3650403at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel" evidence="2">
        <location>
            <begin position="352"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="56222" checksum="1B326DC98711653C" modified="2023-09-13" version="1">MENETGFIRKRAAPLLTRENHETWFKLMRIHLVSKQVDWVLEDIITDIPAATPSIATPSASSESSLPLDQAIRKASYRRHNATALYEMYICLSTDDQEMTYEIRHAKGLWEWAEAKYKRRLLATGRSLLQQYTNFVMTEDQSIDDAWQELSSIARRAVSISPQFQDIKTEDRKIQQLLAALPDSFGSIRDAIDAQVNLSPQDILAILREKQESMIHQGTAMFAKKGFQGKLTCHLCGGDHFMSKCPHLSAAQQAVRNKDKLARVTYPAKRQPSPPRRRSSSPNLRDVLKVMTDLAKQMKESRKPKASSSKPARAHATQEDASDPEIPSEDDDVDEVAHSTVEAKGKYPSSEWLLDSCASSHMTDQDSLFRTLKPLQKRKWIKVGGGYLQATHMGSAVMGGPSGKQIVLENVLFVPGLGVSLVSWNQFSQQFAVQPPSFTLKSLPNFEEEYRLSTRSRKFLSHSMLAYSLKNVTVPLWLTLSPKISGSYGIEDVHTLARDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGT3</accession>
    <name>A0A9Q8PGT3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09688</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766498.1">
        <property type="nucleotide sequence ID" value="XM_047908836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGT3"/>
    <dbReference type="GeneID" id="71989566"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09688"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="111"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="270" mass="30262" checksum="78C0BA2A03007F53" modified="2023-09-13" version="1">MRMRGSTSQLPLKQESTTPKKNLLSKIKSSQEMNQVLKSKEETTKPLKSTTLLSGTIQTRPPLQQTLAPRRPLKNLMPQAQSPTHARRRPKTETAQQKSDREAITARCKVYGHNNLQIGQTFKSRAEIREKDGHSMTSTGVCAGKDGAYAVVVADAYSSFNRDFGKDIDFAATGVNRLRLGVKLDNTFVKAMERSVHGKQPVRVFRGARKTKTVKNTYQTYLLDQSHGGFRYDGLYDVIGTGWTGEEGKKYQVFHLKRRTDQAALDLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF7</accession>
    <name>A0A9Q8PIF7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767365.1">
        <property type="nucleotide sequence ID" value="XM_047911363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIF7"/>
    <dbReference type="GeneID" id="71992093"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12215"/>
    <dbReference type="OrthoDB" id="3655236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="151" mass="16830" checksum="91AB90CB5F370382" modified="2023-09-13" version="1">MASTRQTGATAVPTRNQTKVNIPPWHPPCEQPLQLLYPSHFDDGATRRDIAKVNGHPLGLARRKMIDDFSAAGETHGFTATLSYEEAITGAARFSGQEPPPVTPPFFAITLYHRVNKMELIHGQAIAIIRDSFGVDKPIIRYFEGYYDTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIH0</accession>
    <name>A0A9Q8PIH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767407.1">
        <property type="nucleotide sequence ID" value="XM_047911540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIH0"/>
    <dbReference type="GeneID" id="71992270"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12392"/>
    <dbReference type="OrthoDB" id="10499589at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11158" checksum="B2976EFE1BF99721" modified="2023-09-13" version="1">MPSTPSLSSVEEASNSKVRFSDLTEDWKNATKNGLRSLKRKNPNAKKVVIKGQSHPSSTVATHTNVISCQLQDANGGYLGSGHIDETGEAYPNEKFEKIAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJC0</accession>
    <name>A0A9Q8PJC0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAM1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Outer kinetochore protein DAM1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_12568</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767967.1">
        <property type="nucleotide sequence ID" value="XM_047911716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJC0"/>
    <dbReference type="GeneID" id="71992446"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12568"/>
    <dbReference type="OrthoDB" id="5586015at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990537">
        <property type="term" value="C:mitotic spindle polar microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013962">
        <property type="entry name" value="DASH_Dam1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08653">
        <property type="entry name" value="DASH_Dam1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="160"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO23601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="26092" checksum="F37B1DE6CDA0F414" modified="2023-09-13" version="1">MATSTTPASNDSHQRSTSHSRTRSGAIPSRPTTPLRPPSRTSLRASQSTPTAGASIGGNDFPLAVLEPAFGEFSDAMADLEANMMHLQLLHESIGRFNENFGAFLYGMNMSAFCVDFPEAPIPQSFQRHQDHAADQLRNSPFPKQTRPPDRDAEATFLTTDTSFIENPPETAKKPASSKFSSAPSSTATSRHREAMAQAQARGAAVRGRAAGSGIARGTSGRGGRGGGIPRAGSGIARGAGRGRGSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJE5</accession>
    <name>A0A9Q8PJE5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ribosomal RNA small subunit methyltransferase NEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12710</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767873.1">
        <property type="nucleotide sequence ID" value="XM_047911858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJE5"/>
    <dbReference type="GeneID" id="71992588"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12710"/>
    <dbReference type="OMA" id="VHNTFEL"/>
    <dbReference type="OrthoDB" id="269804at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000003">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="302" mass="33242" checksum="A4C3F79EBE91AF1C" modified="2023-09-13" version="1">MAPDISRIGDSQSPASSGSRSPEAEQMERSLLDATDSTDYVGRRPSASGRDTKRIRTQTQSLPPPRLPNLVAEQAVPIPASDKDTKRLIVVLSNASLETYKAAHGGRNGMKDDKYSLLNSDEHIGVMRKMNRDISDARPDITHQCLLTLLDSPVNKAGKLQIYIHTAKGVLIEVSPTVRIPRTFKRFAGLMVQLLHKLSIRSTTSQEKLLKVIKNPITDHLPPNCRKVTLSFDAPVVRVRDYIQDLGSKESICVFVGAMAKGNDNFADQFKDDAISISNYSLSASVACSKFCHAAEDVWDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJF9</accession>
    <name>A0A9Q8PJF9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12963</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767976.1">
        <property type="nucleotide sequence ID" value="XM_047912111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJF9"/>
    <dbReference type="GeneID" id="71992841"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12963"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="29"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="3">
        <location>
            <begin position="250"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="625" mass="70386" checksum="4A2CCF06A1C2C216" modified="2023-09-13" version="1">MRLLKTGPFVSGNPTTLELHDFPVNQARYAVLSHVWSSPQNEILYSDLLDSCDTSIKRLEGHISVDLAISTLQRKRGWVKLAFALEQADEDGKEWLWVDTACVDRSSSSELAESINSRWQWLEAAAICYAFLGDVPLERWREMKFVRHLASSWLSDGWTLSDLIAPGHVVFYSMEWSRLGDKHELSRLLSTATQVPIPVLEGARSVQEESVAARMAWAANRQTLLVEDRAYSLMGLFDISMPVLYGEGPKAFQRLQEEIIRSSDDLSIFCWKDAEVGKRLHGLMADSPKAFAHSAAYRAYAFEDVPPFDVNNRGARLSLHLTPEKDEIVLAALPCPDPGSQDGYLAIYLRKLPSGDKQYARVRCDEITVLDRRGSLEQIYVRQVIPPSIASSSLISVANGHENGKSAAKHKESVLPTHIFHLNKFKTWDGYKVIDVHYQPPKVQLKDFGELANELKHPENVPEQHHVTFKMVKADHRLTAVILLGRDEDDKRIALLLGSGEDCEPGFDIVECRDLQDLRDCYRPFEPMAFGTMAFGKRHRVVVRAEPIVRQAVKVYLIELTIGALSRIPNMGPIERVDSRRSSIASSKRMSWIVQKVVRRHSQVSSFSRPSSQLGKESNGVSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK17</accession>
    <name>A0A9Q8PK17_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768175.1">
        <property type="nucleotide sequence ID" value="XM_047912481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK17"/>
    <dbReference type="GeneID" id="71993211"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13333"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="102" mass="11924" checksum="852C300218AEC392" modified="2023-09-13" version="1">MSTPTNTNTSNILSSDSTPPAHLSQYWFKNFNGRYVPVNENDPKDVAEFPMQMTPTDLPLYNFHADLSPEPRYRPFTREFLDAVEETIRRERPWYGEVRVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKD7</accession>
    <name>A0A9Q8PKD7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Secreted protein CSS2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768355.1">
        <property type="nucleotide sequence ID" value="XM_047912367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKD7"/>
    <dbReference type="GeneID" id="71993097"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13219"/>
    <dbReference type="OrthoDB" id="5059029at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046624">
        <property type="entry name" value="CSS2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20521">
        <property type="entry name" value="DUF6736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Secreted protein CSS2 C-terminal" evidence="1">
        <location>
            <begin position="114"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="28284" checksum="B2799BEDED3DEAE2" modified="2023-09-13" version="1">MYVVQVYYDTPRSSLSRIERHSDRLHASPSIFLADWRTALLWSTICSTFNRINMRFSLSSSSATLLALLSCSTANGAPAKDVDILFAEQPKPDRWVSYDLGMPFEKSDTTNYTSSSIERRTDVTVCERPTTAPYSCVLLTDFLSPLVFALARIIKDASTRHDCDVTTGSHAGISWKYQANGGSHCDTTAQEKTIRHAIQHHLEDMDAKVLCAQECMKMDHGGKWKGWLLIGPSDGFNEDVYCGPELDFGRCSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL90</accession>
    <name>A0A9Q8PL90_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768942.1">
        <property type="nucleotide sequence ID" value="XM_047913101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL90"/>
    <dbReference type="GeneID" id="71993831"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13953"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF9">
        <property type="entry name" value="L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="29487" checksum="784816001056F384" modified="2023-09-13" version="1">MAPKLTITHIGTATSILTINGINFLTDPFFSPAESSFPLFGDFSLRVEDDPALGLEQLPIIDAVLLSHEDHVDNLDDYGRQLLNGRLVLTTVDGARNLAPRPGVRGLKPWEKVSVKIAGNDFQIIGTPTQHVKGQECTGFIITNEDFGTGRDGLPNAIWFSGDTVYLPEFRKIAEEYHICAAIFNLGNAHAPEDMNDLAGPKYQITMDGKSAAQLFREIKADVLAPMHYESWHHFTQFGDELREVFEEAGIISQVRWLKGGVPVSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLF5</accession>
    <name>A0A9Q8PLF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        </source>
    </evidence>
    <sequence length="714" mass="77434" checksum="F322C5BF1EA77EC1" modified="2023-09-13" version="1">MSSELGRDDSAPASPSPAVARPTSSGIHHGTSSAPNEHLQKAVDDVMYSDIGVTTLLNRLKQSIASARDFASFLKKRSSLEEEQAKGLKRLAQSQLDSVRRGEVRSGTYAQQFTDVLRVHERMADHGMQFALSLHQMHEDLDVLSGNMERGRKQWKHEGLDAENKASAAEAAMQKAKARYDSLADEYDRAKTGDTKSSRRIGLKGPKSAEQYESDLMRKVETADTDYKDKVRQAQTQREQLVREHRPKAVRELQALIKESDSALSLQLQKFATFNEKLLLGNGLAVSPLTDNNSSVSQRSLRELVMGIDNDSDFHNYIAGHQGKIPARPSEIRYEQHPTLAPKTQQPKSMPTTAPAAAAAPPMQAPLTLNTASSQPGSMTSRTPASAAPPSSFSVQPPSSAGYGSGPPQVPSFPTNQPPYQADPTPLRDTYNNTPPYPTHPSERSGTGFSQHQQTTGSIPAVAPTQISPPRDYNGSSFGGPVSAGGFNGPPSAGGFNGPPSAGGPTGPPTESKTPVFGVSLDELFARDQSAVPIIVFQCIQAVDIFGLETEGIYRHNGTASQVNRLRQAFDHLPASSPQLDFRNPSNFGHDVNAVASLLKSFFRDLPDPLFTKVGYGQFIEAAQVDDENQRRDAIHQGINDLPDPNYATLRALVLHLNRIMQNESRTRMTAENLAVCFAPTLMGTHSGVIADASYQHRVLATILINATAIFDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMJ3</accession>
    <name>A0A9Q8PMJ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_14456</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769541.1">
        <property type="nucleotide sequence ID" value="XM_047913604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMJ3"/>
    <dbReference type="GeneID" id="71994334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14456"/>
    <dbReference type="OMA" id="SGNIDWV"/>
    <dbReference type="OrthoDB" id="5357315at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000364">
        <property type="entry name" value="Protease-associated PA domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040268891" description="RING-type E3 ubiquitin transferase" evidence="13">
        <location>
            <begin position="29"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="717"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="119"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="303"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="436"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="636"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="767"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="636"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO25175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="834" mass="90039" checksum="D56887007D44C816" modified="2023-09-13" version="1">MRPLRFVLTLVAFLVSFLFLVLVGPWRGSNPAEYAQDQGGLATYFNWRTPSSLFPPSAIISITDDNSTNFLARPAAFGPLLPQKSLSGQLWIGSGFGDDRLGNGAAELGCSDVPGWDDGSWSAVGGSGKKSSHEGKSAATEGKNKRSVTVEDEDEDDEEHPDEDDGTDDHLHHPLPASDGMKNNGEAARKTKKPTHADIQSLQESAEIAAKVVLLSRGGCGFLEKVKWVQRRGGIALIVGDDIRGGPLVTMYARGDTSNVTIPSLFTSHTTAQLLSSLLPSGSLSTEDATRLGLALGGKSKTTAESSKKLAHKPNFTTTTATSKATATPKPKAGSKSGKQLDTGAQSKPERPRHRGWFAALFGGGSDSADSRRPPSSGNIGWVLQEEFEDDEPIYGKTTTTSTSSSRAAVKTKGPSDGFQIGIHDWRDPDLVAAQKEQHLAGSTSTTTSSVAMPKSTKAATTSLRGGSITPGSGEYAKANHEAVDLSSSRKATEKDTKTSQQSEEEEEDEDHGWLHRLFSTDGDVENVKVEQVARPATKALEPETHVKTETQHRPQHANDAPQMHEGLFVTLSPASMSSSPFFDTLLVLVVSPLVTLTVVYALLLLRSRIRRRRWRAPKSVVERLPVRTYQTMASSAASTTSSAASQASATTPLLPTASRPINARARPRARTTSEVPHGSSLRSDDMASPSLEQIEEKRAAGLAEWRRRYGGKQRECVVCLEEYVDGVSRVMSLPCGHEFHAECITPWLTTRRRTCPICKGDVVRSLARSGGSSSATPPPQQYRDHDSEDEEDVQEQAVTTVNDDPISQRPVSREDEAFEDLERGVTPTPDRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMP3</accession>
    <name>A0A9Q8PMP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769609.1">
        <property type="nucleotide sequence ID" value="XM_047913543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMP3"/>
    <dbReference type="GeneID" id="71994273"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14395"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="681" mass="76908" checksum="7CAD92546D03DE2A" modified="2023-09-13" version="1">MSRNRTKDLKSLNTMNCTATKEDGKRSVADWLTSIGVSLTFLGFLGSMSLLFNIGKTIFIFFSLHSRIPAAPREYFAWIIPDFVRGTVTVIHSTPSLAQPGLWSPSQVRFVSIPATVNCASQQSKRISNTTGPLITTERALEDGRIRARNPIRPSALLEPELSPSLLLTAKHADTTIPAKRRLHTHWMHIRKLRLTSRASPESVFSEDEQERYVVDLDLRTKPMLLAMEWPQFLWFVLALGVNTYCPEFEALGSIFESDSQEADLQSALTLASTSTTMGRIIKVSLIDNKLVGELFPKALHYNLQAALAFDNIMVWSEEQTGGRTKGPVQTFCRSLAADKSSMMRHITAIGSTLELKDFKPSQGITGSTVSDCGKDSTLAATWQWLAYTMYLLKFNQPAPVNEDLVEVRERIILELAQLSEADMEARWDRLKRDTDAPASLITSLKDVMLSTTKSSSYVSESIRLSSLWDKMATSCKTLVNQLRPAVDEAVAVDNTKNSVRLHCDEFGDLKAAIDKQISTIKTYDLVEPNDCASPSVEERSKLLERLQRLPVWEKLQHDTSWHNKADWSHLDLEALDRYRRFATICIVIAPWNRRQWPVWRPIKKARRHCSELTEILDDLGKDVVQDRCAWYELIDRLSEGSIQPGAKVFEFGGFEAPDSPVRKLMRGLERSAPDRVVYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP0</accession>
    <name>A0A9Q8UQP0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine triphosphate pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763247.1">
        <property type="nucleotide sequence ID" value="XM_047906799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP0"/>
    <dbReference type="GeneID" id="71987529"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07651"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="11926" checksum="FAD2463A9C6CA2D5" modified="2023-09-13" version="1">MLPCRKWFLKALGVQQFHKLLDGFEDKSAQAVCTFAYCEGPGHEPIVFQGRTNVGRRTGVDGCWDACFEYEGQTYAEMPKIEKNKISHRGKALEKLTEWLKQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URB1</accession>
    <name>A0A9Q8URB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763893.1">
        <property type="nucleotide sequence ID" value="XM_047905800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URB1"/>
    <dbReference type="GeneID" id="71986530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06652"/>
    <dbReference type="OrthoDB" id="10632045at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="17665" checksum="C91373855079416C" modified="2023-09-13" version="1">MDDDDFDDLFSEVDFLPGSSQVSLTDAAANMSFGGSVGDEAYASEDNLAAPEDTDMLDQWPEEAFEDQEPPLKLEPNAHAIAKIEAVFELMADAMLNDKNELSVTLKVRNSKAKNQHTSPDIDDRTKRICFPGKTADEAWRFGEITFVGFERHRLTFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URD7</accession>
    <name>A0A9Q8URD7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="14">ATP-PFK</shortName>
            <shortName evidence="14">Phosphofructokinase</shortName>
            <ecNumber evidence="14">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_10581</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14 15">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="14"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763968.1">
        <property type="nucleotide sequence ID" value="XM_047909729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URD7"/>
    <dbReference type="GeneID" id="71990459"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10581"/>
    <dbReference type="OMA" id="EWQDQMC"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000008">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="12"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="400"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interdomain linker" evidence="14">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="14">
        <location>
            <begin position="400"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="533"/>
            <end position="537"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="578"/>
            <end position="580"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="638"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="670"/>
            <end position="673"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="742"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO19602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="770" mass="82883" checksum="F60A7DB296DB62D2" modified="2023-09-13" version="1">MPPNTLAAGGKRIAVMTSGGDSPGMSGAVRAVVRQTLIEGCTSYAVYQGYEGLVRGGDLIREMNWEDVRGWLSEGGTLIGSARCKSFMERPGRLTAANNMIEKSIDALIVCGGDGSLTGADKFRGEWPSLMDELVSTGKRTEEEVKPFRHLNIVGLVGSIDNDLSGTDATIGCYTALGNICDVISKVDTTAFSHQRAFVVEVMGRHCGWLALMSGLATGADYVFCPETPPSQDWKAELCDVVKQHRAMGKQHTIVIVAEGAHDRDLNPIKPDMVKDVLSDDVGLDTRVSTLGHLQRGGAPCAFDRVLATLQGVEAVKAVLDATPDTPSPVICMVNNKIVRKNLMDAIAQTNDVTAKIGRKEFTAAMKGRDTDFVESFEAFKIINSTDNTKILLPQGKRMRVGIIHVGAPAGGMNAATRAAVAYLTARGHTPVAFHNGFSGLCRHHDDKPIGSVRELTWLQAESWGSKGSSEIGTNRSLPSEDFKTTAYCLEKYKIDALFVVGGFEAFTAVSELESARAKYDAFKIPMVILPATVSNNVPGTEYSLGSDTCLNQLTSFCDAIKLSAGGTRRRVFVVETQGGASGYIPTLAGLAVGAVVVYTPEEGITHEMLAKDIEYLKDQFADDTGTARNGKIILRSEKACDVYTTKFLADAIKKAAGGKFDAKTSVPGHYQQGNIPSPMDRVRAIQLAIKSLQLIETYTGKSKDQIAADPMSAALIGIRGANVTFDGVEHIGREETDWKHRRPKDEFWMEMADVVNALSGRRKAKGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URR7</accession>
    <name>A0A9Q8URR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10627</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO20020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URR7"/>
    <dbReference type="GeneID" id="71990505"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10627"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF17">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="33032" checksum="CB24DEDF4DF4FA2A" modified="2023-09-13" version="1">MSSSSSEPECQSFYRYYEPSEILAAIGIGLFAVTVLAHSIRMVTTRTLDNSFMILGGTSRLFSTRNPCSKAAWGGQSVLLLLGPSMLMCTITLTHTAFIRALNATRFCWVPLRLQRPLYLAINTICIIIQAVGGITFAAASGKHMAEIGDRLIIAAYVMQMVFWLYILAENTWVTTKVGKEAKRARLNPEGLDAAVPAKERFVHYKRWRQLFGLAISILFGRNMMRLTELGMKFLQENEWTSYAFDGYQIVVVMGVWAVFYLPGKCREVEKAQDRCRGSELEQVQSAERPMLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US52</accession>
    <name>A0A9Q8US52_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-protein ligase E3A N-terminal zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10212</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764777.1">
        <property type="nucleotide sequence ID" value="XM_047909360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US52"/>
    <dbReference type="GeneID" id="71990090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10212"/>
    <dbReference type="OrthoDB" id="193703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056012">
        <property type="entry name" value="DUF7590"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF15">
        <property type="entry name" value="FUSION DEGRADATION PROTEIN (UFD1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24503">
        <property type="entry name" value="DUF7590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23580">
        <property type="entry name" value="Znf_XAF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="82"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="7">
        <location>
            <begin position="174"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7590" evidence="6">
        <location>
            <begin position="281"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-protein ligase E3A N-terminal zinc-binding" evidence="5">
        <location>
            <begin position="678"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="391"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="88735" checksum="EB90FFB8B53F3388" modified="2023-09-13" version="1">MTESPPPALKWSAQFTVTAASTTQTLPGDKILLPPSALEQLLGASSHAAAESARRDLPQYDPYNSSTYSAYRQAESQYQDQRQQLPYPLTFRLVNPENGRVVYAGIREFSAGENELTVSPFLLESLGLKAEDLAQHEDVIIVDDDEEEDEDEKKDEKPAKSVPTITVHAKQLPKGTFVKLRPLEAGYDPEDWKALLEQHLRSNYTTLTNGEVLVVPGGRGVGGKKEEFRFLVDGFKPEVDGICVVDTDLEVDIEALNEEQARETLKRIHDKILKAPGTEQGSSTGGALDLFKAQEGRVVPGDYVNYQLASWNRTQPLELELEAEDDDDEDLALLVNPYSTTLRSQPRLDEFVFGDLDIRPRKRIRLEPTNVDVEHAESLYVAVHAVAPRAAETNGDGVQPESSGEPRRFTLRARHPGPDEKTNGDLPATVDTVPPNEGDVKCKNCGQWVPQRTLMLHENFCLRNNLLCPKGCGQVFQKRSPELASHWHCPHDESHGNTEPGHQNHDSIFHPPEVLRCSDCSTAETFPNLPSLARHRTTTCPGKIILCRFCHLEVPQEGDPDVPNAEALLSGMTPHELADGARTTECHLCNKIVRLRDMETHIKNHEMDRFSRAVPIPCRNINCGRTLDVCAKNGDTRAGTRMGQGPGNDVGLCSQCFGPLYVSMYDPENKALRRRIERRYLQQLLTGCGKAWCKNEFCKTGRKNLDMSTNITTKDALPMIKPYLETAKDTPLHFCVDESSQKRRNLAGMLAAEDGGQSGKGGFAVKWCVGALEAEGGDLDAARVWLRNWAPARSEERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USA2</accession>
    <name>A0A9Q8USA2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TNF receptor-associated factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765000.1">
        <property type="nucleotide sequence ID" value="XM_047910467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USA2"/>
    <dbReference type="GeneID" id="71991197"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11319"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="117"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TRAF-type" evidence="7">
        <location>
            <begin position="261"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="261"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="67484" checksum="3CCB5AF2B4EAADE6" modified="2023-09-13" version="1">MSRSPSNFFRSNRNSASNPSPWSLHRRGSSTNDVLAVNPYETERSASVQRSHSSTRQADGTASGTTTLTRGMERLEKRRTMEERNFLQAKARSQNLNPPVDLRMLDYVTEYDDNLMCPICRCPFVDPVVLNECDHCFCRDCIRQTWTTNTNYNPLGPRGDCPTCRTPAKLGPRSSTSKILGNILDDLLVKCPKADHGCKSQVKRGEVQDHMSIYCGYAMVECPTEQCELPVQRQYAKQGCLHYGVSCLACREDMLRCHLETHWRSKCVDRQIRCDQCKAKIFFKELTEHNTRLCPAISIPCPGASLGCNTRSKRREAEFHAKSCTLAKLAPVLSAQQQRLDDQEAAQRQMNRKLEVLEGGFGRMHSILYPRADDPDQNSAIPSQIPLIENHGLHDTALPADGESPPVIDPAELGLDANGNALPSPVEQRRRFSEATRPPFNRALPAIPGPRSGNLPEPFSPDFDLASPFPPPATNGGPYASPLHHMLSMHESLRDEMSRLNTALQELDGRHSMQILNENMRTREEITYMGAQVAGLSRQVHWLTSTQLQRQSQGSTPGAAGPSDVATAGSSVEAAINNAVRGAARIVNAGREGMPMRRNTSEEGRTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT19</accession>
    <name>A0A9Q8UT19_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterigmatocystin biosynthesis monooxygenase stcW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765810.1">
        <property type="nucleotide sequence ID" value="XM_047908828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT19"/>
    <dbReference type="GeneID" id="71989558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09680"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="36291" checksum="42D412C0554E6484" modified="2023-09-13" version="1">MQDNPEYYLKYRKNVETEMVALGEFFHRNTPDSDAARKYAEGLMKARLGGNDQLASKLLPTTFPVGCKRLHNGYLEALVQPNVTVFTDGGLERVTPTGFVDPQGEHHDVDIIICATGFNTSWVPRFPIIAHGVNLQDIYTDKAVGYVGVAAPSMPNYLTIYGPYGPIGQGSAMPVIEAFVNYILQLIQHVQEEDVKSVTPRQQVIDQYAEHADLFNSRTVYNGDCRSWFKGNKKEGRIVLHPGTRNQYLLLMSKPRLQGYDFTYRSGNMWNWLGNGQTTRDYDGRDLTWYIGKIEGQDVQQLYDTPKFLYKPETNNTAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT40</accession>
    <name>A0A9Q8UT40_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding monooxygenase moxY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765809.1">
        <property type="nucleotide sequence ID" value="XM_047908832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT40"/>
    <dbReference type="GeneID" id="71989562"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09684"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF1">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE STCW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="37716" checksum="E71F36FACD748D9F" modified="2023-09-13" version="1">MKFNEVVQSREWDEEEGLWHVSVRNALTGQIINDTCHVLIGANGLLNSWKYPPDANVQDFRGRLIHTARWPDDYGPEQWANDRVAVLGSGASAIQVVPTIQPHVKHLDVFVRTPVWFAEIAGHSGENTDYAPEERERLRNDTEALVTTAKSIEDGLNGIQGIKAMMTSSAESQMVRKLFQTRMREYLTDDKIYRPLLPDFAVGCRRLTPGNPFMKAIQKPNVSLHKAAVNQVRGSTVIGDNGDEVEVDTLTCATGFDVGYVPKYRMQGRGGITLQDTSPGIRSWRVVIYHRTLLMTDWRRSSTLSSLRSRRMGGPREGVAWSMRVLARQRSIVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTD3</accession>
    <name>A0A9Q8UTD3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="3 12">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_09595</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="3 12"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766036.1">
        <property type="nucleotide sequence ID" value="XM_047908743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTD3"/>
    <dbReference type="GeneID" id="71989473"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09595"/>
    <dbReference type="OMA" id="RKIHMLA"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000040">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023617">
        <property type="entry name" value="Tyr-tRNA-ligase_arc/euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006330">
        <property type="entry name" value="PRK08560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006588">
        <property type="entry name" value="TyrRS_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="361"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO21670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="46456" checksum="BA985ABD7E6F8EDA" modified="2023-09-13" version="1">MAEANGAPGAGLTADQKYELISNNLQEVLNKEIIQEVLSKNERPLKIYWGTATTGKPHCGYFVPMLKIAEFLAAGCSVKVLLADVHGFLDNLKAPIELVKVRAQYYEHTITTALKAVGVDVSRLEFVLGSSYQTTGESGAKYFMDLLRLSCSVSGHDASKAGSEVVKQVEAPPLSSQIYPLMQALDEQYLDVDAQFGGVDQRKIFTLAVEALPRVGFAKRAHLMNPLIPGLQEGGKMSSSDPDSKIDLIDPPEIVKKKLKKAYCPPRTVEGNGVLSFVEYVLLPASALKNNGTPKFVVQRRDAEPLEYDNIKKMQEDYLADVLQPQSLKPAVTDALLEIMAPIQETFQNSKEWQDIEKAAYPPPPAPEKKAKKVKNLGSRFPGAKPAADGTGAIEAKPDGHVEGPDAEKASLATPEDAVTKLSVNDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTE7</accession>
    <name>A0A9Q8UTE7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase mpaDE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09473</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766157.1">
        <property type="nucleotide sequence ID" value="XM_047908621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTE7"/>
    <dbReference type="GeneID" id="71989351"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09473"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="82"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="422" mass="47405" checksum="09298B57A98017F6" modified="2023-09-13" version="1">MREHIYSWKVRNTHPSRSHHPTLQRSHNMSNQPQAKPAPNLNLPKSDNVCEVAIIDTTCDLVCHPSTLIEPDIPSHEWLNLPTYSFYIKNKRSGEQVLFDLGSRRDWQNLVPHVYDVVSVRVPGLKVEKEVIDIIKDGGVNPDEIKAMILSHWHYDHSGNISRLNKKTDIVVGPGFKKAFEPGFPANPQSTFYEADFEGRKFIEPAFSDDFKIGGYQAHDYFGDGSLYVLNIPGHTTGHISALVRTTPETFIFMGGDVCHFTGVIRPSQYIPLPDPIPKNTVLDPRLSAPCPCSIFTKCHPDQDNSRTSAFYRCSTGGPYGSWYDDPATAMQSIASLFEFDADPNVMVLIAHDSAPKDSLTFFPNGTLNDWKSKGHKEAMHWHFVNELPVGGKQERNPLTDGLYRDDGQGLKKVKTMYGEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU80</accession>
    <name>A0A9Q8UU80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-rhamnono-gamma-lactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766979.1">
        <property type="nucleotide sequence ID" value="XM_047911168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU80"/>
    <dbReference type="GeneID" id="71991898"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12020"/>
    <dbReference type="OMA" id="IAWRTAM"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052350">
        <property type="entry name" value="Metallo-dep_Lactonases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569">
        <property type="entry name" value="AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569:SF2">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="7"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="342" mass="38668" checksum="49184A94E224FD7F" modified="2023-09-13" version="1">MASNSIIDAHIHLWPKNMADEAGHSWMTLGMPLAKEHVLADYYQASPQGHVDGVVYVETDVRYAKPSGAVSEWAKNPLDEIRFLRNVVEGGYGERDSKMLKAIVAWAPMDQPPVVLEEWLRLAEEAAGQETWRRVKGFRFLLQSIHDEKKFVDVVSGSNFINNLKTLGRRGFSFDVGVDQQSGGVWQLEAFAKCMSASHQGVPEGSKVVFILNHLCKPEFQKDGAGYVRWRRAIESMSRCSTAYMKLSGAFSELPQAMGGTTNIAHHLKPWVSHVFACFSASRVMFGSDWPVCNLKGPRQEDSWVCWKDVVEFVLDDSEYHFTDQDRERVWKGTAMEAYQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUB6</accession>
    <name>A0A9Q8UUB6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha,alpha-trehalose-phosphate synthase [UDP-forming] subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766983.1">
        <property type="nucleotide sequence ID" value="XM_047911607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUB6"/>
    <dbReference type="GeneID" id="71992337"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12459"/>
    <dbReference type="OMA" id="TSWDKRR"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000099">
        <property type="entry name" value="Alpha,alpha-trehalose phosphate synthase subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="953" mass="107369" checksum="58B124158FF8A4EE" modified="2023-09-13" version="1">MATNLTVSLFLPNTISFHEEVEAPSRRRSPPFQLEQRGSSTVDLPTRHSTASLFNARTNGLGGGHTPPLTPAIQSALNEDFFTPGIDAKKRHFAKPGDPRSMLRSDTHAEWGQTDAVFNQPRSRAGPLPSASIQDFAKVYDEMKEREERRRKKQGRRVTKASPGQSKFNPRGPSSERGFDGKTWTVEPAIHGNGGLVNAHRETSGDRADDSTDTTWIGTLGFPTDALPQDIKDEVRDKLINDYHSEVVYCNDKDIDGHYAHYCKTILWPIFHYQVPDHPKSKAYADHSWEFYRNVNRAFADKVIESYKRGDTIWVHDYHLLLVPGMVREKLPDAKIGFFLHTAFPSSEVFRCLSTRKELLEGVLGANLISFQTEEYASHFLQTCSRILAVETTAEGVQIDDHFVNVTHEAIGINPFMFMEAREDEEVQEWVQTIAEKYKDKVIIVARDKLDHVHGVRQKLLAYELFLNRHPEWREKVVMIQVATSTNEQTELLTTVSDICTRIDSVHSTLAHQPLVFLKQDIGFAQYIALLTVADVLMISALRDGMNLTAHEYIACQDGKGFQKMHGPLILSEFTGSAAVLGDGAILINPWDYQGQADAIKQAIEMGNEERKSRWEKLHAVVEERTGGFWSQRLSKELDRAFEEHHARASASVPRLSVSQLTEKYKAAETRLFIIDYEGTLAPHKTASGIPLGSPARVVEALNDLITDARNIVYVMSGRKPEELENHFRTLPKAGLIAENGCFVREYGIDNNEWTSFVDLKEVANWREQVKGILGYYEERVEGSYLEERHCSILLRYEKAGDQEAALRQAAECADQINDSCRGLDIHAVPIKQAILIEQQNLTKGTAAKHVFELIERQSKGLQKPDFMMVAGDDREDEVIFKWANALGKEGVVKDVYTVTVGKRNTLAQATLTQGSTGLLTVLAKLNKISADMLPRDYFNSQPNPKRVNTFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUI7</accession>
    <name>A0A9Q8UUI7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767309.1">
        <property type="nucleotide sequence ID" value="XM_047910907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUI7"/>
    <dbReference type="GeneID" id="71991637"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17800" checksum="111EFDE461837821" modified="2023-09-13" version="1">MQSILQYRRFKRTLEVQLERDQAKADALRRGQYTSNQPDSPTPASVDEEKKSFEQDIERADFTNTASHATRPAGASSQVGTVLTGIQIRKRTTREGGDGHVFVVAGMKERTTHRIRTIGRFRSAYDAPSWLQASVVSSVLLLLSIAVLCLKPLQSSALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUL5</accession>
    <name>A0A9Q8UUL5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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            <dbReference type="Google" id="ProtNLM"/>
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    <sequence length="213" mass="25647" checksum="656FE6B4C46FD536" modified="2023-09-13" version="1">MLKVYRLVDPLILECPHMRSLYQTRTFTHLIASHSKSNKSNYLITTYTIARTHNPEHRHRAIYKINHHQQYHDTPHPTQANLTTTSNLKMYRPMYTSPLTRECIPWSQLSFKERMNSDEAKIDLRNLNIMIFFVLPMLFMFCALGYYRRRGDWYKRRVQALEEGIEKMDKGQQDWVDLGPNLEGRKKLIRQLEEGRRWCEDMVQHYRSNDVLQ</sequence>
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    <feature type="chain" id="PRO_5040188412" description="CHRD domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="2">
        <location>
            <begin position="49"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="195" mass="20790" checksum="82ABE4B38971A7DC" modified="2023-09-13" version="1">MKASVVALSLFAAVGLAAPEAHYGKWSDKNKWSDNGVKWDGEKYDQFTSVFKVKATPDQVRNGTTPTGGQEGACGYYELALNSKKNFICYKIRLSNFGNANYSSPADTATHIHEAARGASGPPRIAFPNPAYEGKSEDRLSIGCLSAPFQTGVNISGIDTGFGFHVKQIEANPAGFFADVHTDKAVPGAVRGQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW43</accession>
    <name>A0A9Q8UW43_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768888.1">
        <property type="nucleotide sequence ID" value="XM_047912991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW43"/>
    <dbReference type="GeneID" id="71993721"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13843"/>
    <dbReference type="OrthoDB" id="10262962at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="519" mass="57151" checksum="71DDF76995C361AC" modified="2023-09-13" version="1">MRLGVPSYKITILFIMLTIQTVISIMMRFHQKASSLFAAMAGQAIFSNAQAGNASCSESTNASLSWHPPVQYDVNSLSSAINGTGVYGFIFNSSQGPLATYNWCNMPHTNPQTYSKVSDEYKLEYVEVIHRHHKRTPYADNTFPREGYAWSCSDEGLFYGGKPLNPHGNESASTYWSVYTPESNPLAPQGFNGTCRFPQITREGLDDSHQHSVDLKAVYSDLLGFIPREYDEKAVSYRVTNNVITSQVASMLIAGMYPSRAGQDTPLLIQPDSVDSLEPGYSCSSASSLFSSYGSGSSSPAWLEHINASRDLLTRLDALSGVDPDDSDWHMSYDHYFDNLSARLCHDKPLPCNVNHTDDCVSLAEAEEVFRLGEYEYSFIYRDSNQSLAASTGSYGIWLAELAQNFRHAMGTGASSTANTTPASIKYRHNVAHDGSISRLLSILQLEKMVWPGMGAEVVFEMYSKNGCFFLRVLWGGQVLRSSHPDFGMMSMVPVSTFLAYVDGLVGVGASKIPALCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWV6</accession>
    <name>A0A9Q8UWV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090176">
        <property type="protein sequence ID" value="UJO25421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769787.1">
        <property type="nucleotide sequence ID" value="XM_047913803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWV6"/>
    <dbReference type="GeneID" id="71994533"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14655"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="14980" checksum="AE7C31766B362DA4" modified="2023-09-13" version="1">MSSPKPTTIFIKTPGSKAKGTKSPKTENQRMPETPSRSERPTWSPKSLPTTPSRTESSSHARSASDSSSGLRSILKNREAEMNPSMFSPDAGRENTHGKAIIDALWQEKKKSEEKAPAKGMRSPPRRKSKSSGEGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXP4</accession>
    <name>A0A1P8YXP4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp7</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp7</name>
        <name evidence="3" type="ORF">CLAFUR5_12426</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943113">
        <property type="protein sequence ID" value="AQA29284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXP4"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573451" evidence="1">
        <location>
            <begin position="17"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="12811" checksum="BC31605D0E0D9CE8" modified="2017-04-12" version="1">MHLTFVLAVVVPAALGHYLTIYSNIGCRKGSQITTQDFGHERPGWTSGCKSISPSGRSIDMHFDNRGTDCTAKIYDDNACQHELIGMSGWVDPHTYGCLAHDDWGKGYVNSFRVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5K4</accession>
    <name>A0A9Q8L5K4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755652.1">
        <property type="nucleotide sequence ID" value="XM_047899466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5K4"/>
    <dbReference type="GeneID" id="71980196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00318"/>
    <dbReference type="OMA" id="TGIDTCL"/>
    <dbReference type="OrthoDB" id="4114509at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53123" checksum="D959EC0E1A467B5C" modified="2023-09-13" version="1">MAETITADYLVIGAGAMGMAFVDTLVSDTNATIVMVDRYARPGGHWTTAYPFVRLHQPSAFYGVNSRPLGEDRVDQVGLNKGLSEMATVDEVCAYYSIVMHQTFLPSGRVKYYPKHEYLGEGEWRSAVTGSLFRLQGKDGKQPKIVDATYMKVTVPSMGPPPYQVAAGVKVVPVNDLPKTTRPYGAYTVVGAGKTGIDACLWLLNNGVDPKLINWIMPRDSWFLERGGIQPGPAFAKKTSKSIADINGAVMSSTSPEDLFLRLEARQQIMRMTDKIWPTMFRCATVSIAELEQVKRIENIVRVGRVQQITTDEVILDSGAYKPAPDTLYIDCTADALAKLEPLPVFRGNQITLQSVRYCQQVFSAAFIAHVEATYSDDAQKNALSRVVPHPDEAIDYLIVTLQSHRNGLVWASHPKTAAWLSQARLDWFGTLLPPPPEDPAEAKAYYMAVAAQVQGIIDKLGALIDQLPEKDAARAKAQVART</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7B0</accession>
    <name>A0A9Q8L7B0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase ATXR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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            <end position="192"/>
        </location>
    </feature>
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            <dbReference type="PROSITE" id="PS50280"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="364" mass="40724" checksum="8C34B38E3F10C04F" modified="2023-09-13" version="1">MSCQAVTVKRWLSDRASPSSVLLGTPSTKVQVSKTGSGLGLFATRHIEAFSVLLSDAPLILMEPEDDLPELYQKFTRLGRGDQEKYLNLSYHENPSRDALLKDKLLQRGFGKEGLQEMAQVAGIMQNNAFNVDLGDGRGSCHRALFPHVARLNHSCIPNAHVCFYPEQSPGRMVVHTLRPLEADEEIRISYFSILLPYAERQAKAQKWGFTCRCSGCDERAGGFEGSESQRRMCRDFATRQGEMMKRAVVTMMELNDVAGMGRAAVYQAKREDGLVPTLPDLFDGLAMLQAKVLLVQKRETERDSVLSLLEEAVEWEARITGTRSQATSKRLRRLAQFAQKQGPLMIPAIELDASGSYRVKWPQ</sequence>
</entry>
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        <recommendedName>
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    </protein>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <source>
            <strain evidence="2">Race5_Kim</strain>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <begin position="1113"/>
            <end position="1319"/>
        </location>
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        </source>
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        <source>
            <dbReference type="EMBL" id="UJO12192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="1320" mass="145916" checksum="4DCFA58C127047E2" modified="2023-09-13" version="1">MGAPVSPERPSLQRLKALDALPDRDAQLTEAKSLCNHAARAEMITKWVLGKLKSQAGLREKDGPWDLLSFCCRLLSPHKIAVLLGSNGLFDIVHTTFSAADLTARALIAIGGFVHLLFELGQSVHGAAIKSFLSIASTIAATICGKWLHNVHLLTQDTQFGAESDALYLYTDAILQLWTSRKPSAQDDELFNNSCLVDALVIVSRLRDSDALGSQKRKRSGAHARISRERADSLERHIAKHTILPARAAFFKHRQQQARKPRIKASAEEPQSIKERLGSLKMAIWSASDGNALHSVPLVLDIALRSKSAPTPRDRMNERPWLEELWIALRGCFSNQERSVKNQTLAVLLQTLRQQSTTISHQILSAIVKEDVLPADDSSDSVDWYVAAGVVNLDATIFNDRALAQTLFDHITAASSSASHEDNNVLDIRDDIVVPIMKVYGKSRSLRTFMELWGEQLQQEQNFQPKSIWTNINDSFAELVEEALPQAQVLLSIHDSVSLLHETAALSMPTLNTTLVTLEALLRGVRADSTVAKLHDELDELLGNLFTIVELEAFEVHKELPVQLWRLLTRVVAMWYPLRASKQQDQGAIGDRGAALLARKSFRIALAQSTMADTASDRSKRTVEAAQNFVATMCCFFKDVEHKQCKTTCEEGIKTLSNQHELAVDTFIAQPRIFQHLKSTRRKSLFSEVAQDAYDSPNVDQIRAVIAASRSTGGREVLDDMLTVLKERAERQAGQSNAILLSPMQDVGSISLTRAHRVELLNVILEMDDTEANQLPGRLAMMLELASPPCLEAKLFDDALVVWGILSSFDASGILLTHASATILLLEELVNCVLKAWLSTHQRQRSRELLADFSRNLIEHAQRISSGPDKTSPAHCAAIAVVKTAIKVLEGDNAAVVASDLAHRESKHMRSYIKNLLSDADTILTLAEQAEHRVTGSSVAEPLRNVLEAVSSIPESIWHLSGQPYTKASEVVRRTVAVLDARKTDAGTMEMASCTSTACFRLACRYLPDDPAQLTVLAHNALQHKLDAAEYRKVLVEYEARMKSFDHDNKIEALLEFKAARSLTSAHSLALQRAALHSFTAEDVEADKPRMTAIFHDIVEAVSSSHDEHVQRAALVILAEMAKEKSSTVNQYAVERTISVLVQLLQSSSNTNAIYANVCNVLGALFAHHRSRLQGRFHLVIALLQTLLSSLFHKTVGTNEASIRHARSLSKLLETFCNPPQARHSKKSSHLVDEARKAQAHAGQFAQYILHHYCSQILTATLGEGVRDALSPGLWAVIEAIEVNNADGIKNLSAAMNNSERAVLRSVYDDWKRFGKWEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7K1</accession>
    <name>A0A9Q8L7K1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981229"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR021838">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490">
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
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        <location>
            <begin position="411"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="439" mass="50877" checksum="483464D8E06878B7" modified="2023-09-13" version="1">MVFRRFLPFFLAAGVATILFFTVVQGRDVGLPWQLVGLGEDVGPTEEEIKSGENVLPDVKHVDQDKHDGAGGSGRDWHVFQEPKVEETSPYPQGKMKPPGSNYTKGLVLPRLKREDTGWVEEELVDLMDEELLRSYIYVVDDPTAALRPPKNKGHEVSVYLSYIIDYYEHLPDVSIFMHAHRYAWHNNELLNTDAAAMVRALSPERVTREGYMNLRCHWDPGCPAWLHPGSTMENRDKQEEVILADSWSQLFPLDPIPTVLAQPCCAQFAVSRERIQETNKMRYIYMRDWVMRTDLNDYLSGRVFEYIWQFIFSKTAIHCPSMSACYCDGYGICFESPEKFDEWFKLKYEKNQVNEELRMWRVKANKIETLHGNAEDGRIKEEAKLEVPEVGMDRELENWVAKLENEMEKRRQKAIERGRDPEQRAKGSGRGWKKGDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7M2</accession>
    <name>A0A9Q8L7M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756718.1">
        <property type="nucleotide sequence ID" value="XM_047900294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7M2"/>
    <dbReference type="GeneID" id="71981024"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01146"/>
    <dbReference type="OrthoDB" id="5427526at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="43127" checksum="19AAA8803D711A9F" modified="2023-09-13" version="1">MMEPTPPPPLTPIRTHTMSPVESPSPTHSFREHLRRRTSSFSSNHDRSPVATTPRSSRRFSHVSVSRLSGEFGTPVDEGSGLGNLADELDQLDDDDDEFVEGETLDTLQGLHEQPEADEASRDSGIGISYKDAAAAKSNTANHVRNFSKPFTGKVEKPPDEEEEEDGEEDRFTPDLEDLMHTIARMTSYTSTTEDPLIPRTIGLLQDLGNQTSLEAATQRYTTSTNSLTAHLASQSRSLQALVQTLYPMFAFTAPLDPAIIEETLPLVDALSTEIPQPDVITLQKLQKLDRETADVVHALSQLTDTLQMGKQSTAAAARHLRSTQTLVEDLRLEHERADIARHELTKSDWEDRLRTRWCATECKDIISGFEDRCNALRGDLEQAIQAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L802</accession>
    <name>A0A9Q8L802_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756224.1">
        <property type="nucleotide sequence ID" value="XM_047900579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L802"/>
    <dbReference type="GeneID" id="71981309"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01431"/>
    <dbReference type="OMA" id="TDATFHT"/>
    <dbReference type="OrthoDB" id="3913483at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="168" mass="16986" checksum="B8949318E9BF9929" modified="2023-09-13" version="1">MSDSTFNVTKEDVRKVEQQASKAVGGDVPADSYAAGLQSIVDKANQNKGDIIAERQGNLPLPDQPPQASDFNSADARTVDVGSGGLSGGQGDSKGADGLRGPATGGSAAREDPSVTGGNIQGQGVGRGTVDGGLPNDAVTREKKDAQGLADTTGKDYGYPQKNDPASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8K2</accession>
    <name>A0A9Q8L8K2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M50B-like-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757287.1">
        <property type="nucleotide sequence ID" value="XM_047899354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8K2"/>
    <dbReference type="GeneID" id="71980084"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00206"/>
    <dbReference type="OMA" id="LSVNHTQ"/>
    <dbReference type="OrthoDB" id="40823at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29147" checksum="C1685429B78999B2" modified="2023-09-13" version="1">MAPLDDTHFATFAPATMDHHISKRNLNVNQTQAVTLGVIAIYAVAIAILWNVPYVRMILWPFKMLTIAFHEFGHAFAAILTGGKVESISLDPDEGGVTHMRGGRQAITLPAGYLGSSIIGALLTFCGFNIVASKVASIVLGVCFLLTLWWARKDWLTIGTVLAAVGLLVACWFIAHAEALRFVVLFIGVMSSLYSVWDICDDLVLRKVNSSDASVFAKRYGGSSRCWGLICSVISVCFMAAGIVAGIAAFRQDWDQQEKDSKGFIPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9N5</accession>
    <name>A0A9Q8L9N5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional activator protein acu-15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757635.1">
        <property type="nucleotide sequence ID" value="XM_047902183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9N5"/>
    <dbReference type="GeneID" id="71982913"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03035"/>
    <dbReference type="OrthoDB" id="2110361at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="761"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="761"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="786"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="807"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="840" mass="91678" checksum="8CF8852BFC95071E" modified="2023-09-13" version="1">MDGNGQPPPGAPPSAHRNSGPYAASISSHGSAPGHAHGAGPYAAPDQHPLANMPASPAVMQAHMNGMGQPFPYPNVPSSAGPAGLMADQYMNDSPGISPTHASAAALSAQQKRAYRQRRKDPSCDACRERKVKCDATDMSSCSECSSRGVKCQFTKETNRRMSSIKQVQDLEKQLSMAKQQINQLRGMLQDGGASDVNANPPNVPALQLPETTAKERRPAPPALEAFDEVRKNIRTYSKGIFKPPPPYRQFGPQPTFSNAAHALPPKHVADRLIAHYRGSVHVYAPHLHWPTFVQEYEELYRTGSFQQCRHIWVALFYAVLACGTLMEPVSKDTSEESEGAQYLNKAVSSVNTWSDELTVDHVRVSLLCSIYFMEMNLRSPGWVWLGAAVRISQDIGLHTDNGPYPPLETEMRRRVWWSVYNWDRIISLEIGRPLLIDDDDCDVSEPVPVDDDCIRPTGIVMPPPGQTIPSGLLAVIPVVRTTAQVKKCFKSPTVAASTLAMCDEHFKSIMASWPDPYPIQSQAPLDPRLLTAGCSLQTQRFFLYRHNLSPACRQSERRDALDRCVSVAQDTAHYVQRTLQHPSTSPGQGYLSPGHMANWAGRVRTMCPAFFCTHLWRCELVLCLRGEFAAALTLSHVSAAIGDLRKNNVGCGRFLAFFLDKLIGRLRAGASFQNLELDEEMLAYASGDMQGCADDAWAWTGSETGSKLHQPQAIVNGTGGGEKPALQAEQLSTSTLSDREVQEWGGWEHIQRTLDQLLQDPQGQGQGQPPRLQSQQPPNQQAPGTYPPPPPPPQPSSLGPPPLPQPGSQSPNPNANSNGSSSNGNTNGAAGRISIQDIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA48</accession>
    <name>A0A9Q8LA48_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quercetin 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757952.1">
        <property type="nucleotide sequence ID" value="XM_047902420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA48"/>
    <dbReference type="GeneID" id="71983150"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03272"/>
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    <dbReference type="OrthoDB" id="2588190at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02215">
        <property type="entry name" value="cupin_QDO_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Cupin_2"/>
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        <property type="entry name" value="QDO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
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        <property type="entry name" value="Cupin_2"/>
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    </dbReference>
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        <property type="entry name" value="RmlC-like cupins"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="73"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="39339" checksum="7D768320286D06E0" modified="2023-09-13" version="1">MASTNGTNGTHSLLKATDLPPGKPGIPYVISTQDGEIIYIPLSKSATRLLVTGKESENAFAVVGSSGSQSDPIGFHYHREAHDVFLCLKGKVNVWANDKCRTCEAGDFASVPPGTVHQYQILGNHSEMVGLIVPGGWEEFFRFIGEPYNGPAWPLDDQRNVFEALIPKLKAAAEKFDMVPQPHLKQFGPQPWEEGENTLPGKLEPYFLKSGSGPAYLAGGTVVRPLIATAESNGKFVIGSIEGSSHHHEHDLFNEGRKLKFDSTHHAFQVVEGAVEFTIGSSTPSFLHAGELIYVPAGVELNIRLRSRFAKFYSFSSGKGLVELLMKIGKPYSAPIPPEKADRADHGALDGLRAEHGFSVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAV5</accession>
    <name>A0A9Q8LAV5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-rRNA-processing protein las1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758471.1">
        <property type="nucleotide sequence ID" value="XM_047901995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAV5"/>
    <dbReference type="GeneID" id="71982725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02847"/>
    <dbReference type="OMA" id="WLWEWYW"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:endonuclease activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:maturation of 5.8S rRNA"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="419" mass="46999" checksum="4C8CA1AF4B14D77F" modified="2023-09-13" version="1">MARYTITPWRHHSDLLKVRQQLYGRSKDGQDHRRHAVNRVLAWKLRGSLPHAIESTALLIDAILHHASSASNSPFSIRAVYTAAFTRFVTGFCDIGRNKERSLEPSSMLDIAKQIGMPVEFVALRHEATHEEMPGIGRLVKVTERALKWLWEVYWSKLPEDESAEIVAASLASLKDEARRLLKEFRMTHREALRAKQSVVAQDSVSRTSEVCRSLCGNSNAKMSAFVEVLIQDRLLSPSKRKLGALMDGAFLIWDPLLKDIARKQRRFIPCLVTGILEAVGASSSAPAARDVDKEALSQWLIQIDFDENWMASRSDHEQHDLEVEIWKWCTLHANHWTSWLGQKLEQHNDAQIPGEWAELLQASRLGYEEAGEDNAEDLADPDVDARGALSAVGNASQSVPSPWSRVAIPISTPIGVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAW0</accession>
    <name>A0A9Q8LAW0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758428.1">
        <property type="nucleotide sequence ID" value="XM_047901843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAW0"/>
    <dbReference type="GeneID" id="71982573"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02695"/>
    <dbReference type="OMA" id="GTQNRNG"/>
    <dbReference type="OrthoDB" id="5411518at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290:SF6">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="371" mass="41486" checksum="210CA71539B593F6" modified="2023-09-13" version="1">MPPSIPKKAQTEGSATFDPDAFFESWSKEEAQPFLYQNDFRKFIIKGFGLGLRDDYPYKATAEVTLLQAQTYIEFGGQNGLHAWYRDAEGQARPSPTASDIAAYTDIFRPTTSTTKALKALESNAKKDSVRMDAAKHLLSLYSPPSESSKLVVNKSKTHINPYLEVWAWSNQNLEWGGPEERTKDVKISHAVLPILYHHFGCVCPSYEALSYIQQVAKGRRVLDLGSGNGYWTYVLRRVESNSKKAVKVLPIDNGQSEWRTMWVGDTVEVDGEKWLKQNGGGKEDVLLLVYPVVGQEFTSKMLRAYAGTTIIAAGTQNVNGFTAFAKETIADWMAREMSSWEKVLQIPLPSFAGKDEALFIFEKRPDATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAZ7</accession>
    <name>A0A9Q8LAZ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03305</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758402.1">
        <property type="nucleotide sequence ID" value="XM_047902453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAZ7"/>
    <dbReference type="GeneID" id="71983183"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03305"/>
    <dbReference type="OMA" id="AVYQEHK"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="119" mass="13791" checksum="ACE689307255E147" modified="2023-09-13" version="1">MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB10</accession>
    <name>A0A9Q8LB10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758561.1">
        <property type="nucleotide sequence ID" value="XM_047902922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB10"/>
    <dbReference type="GeneID" id="71983652"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03774"/>
    <dbReference type="OrthoDB" id="10661006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040277523" evidence="2">
        <location>
            <begin position="22"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="677" mass="72486" checksum="B912F8D4A6D58558" modified="2023-09-13" version="1">MAVSLRKILLLGAAAVGTASAAIMATPSEVTPARSYTKTHVTILEKRACQTYTFAGPAPCLSSSCSQEFLTTSVCDDVAPYPGATGTQFEITTATDGKHTGSWTYTGKQAATVSVPNPSGLAEHPAQENWTFQLTDELKGKIIDALNDACANSGQFSPDKVRRDPGTPICNVQQLGALEAGYGYDQGPDSLVLLFQPIIIAAGGVGYAMEVGQAYARRAHAITNIRGVLATVAAVAMVYQLGEVGYLTNQLEVPPNIINDVIEDSNNHVDIPDAEHDGGGGNGGGSEEEGKSCPIDATINPDDDQGQDGNPPDDIQNPLGGGGSAPETCATTILAPTPICTLTRQSNNPYRPSQQCLCPDNGSTRTVSASTSTITTCDGNGSGTHIDVCPWTTPPPTSMDVPICQTSTQSGFCTPTVRPKSWNLPETTPSHYCACSSKGMDKAELYYPSTAVVEVCSEGQADRVSKTKTLVCPYTTTPPTASKISFPAPATKTYAGGEYPEVNVLKPFCNKFKLTDYGKDYTNGYSQLGLEEKVKDFCKKAADRNDEFGPDDVERSMYRHYVMKGSMPDPNKNGEIVNQAFPEGPKAENVALFAHYEEKACPVGDDTKVFKFKGNEAKCQQNLIAAAVECQFFKRGHDMTHQYTFYPGGGRYADCMWWEISAELKFSYESDVDSINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB32</accession>
    <name>A0A9Q8LB32_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758500.1">
        <property type="nucleotide sequence ID" value="XM_047902824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB32"/>
    <dbReference type="GeneID" id="71983554"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03676"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="30238" checksum="AAD9270FA8B24D55" modified="2023-09-13" version="1">MSLSKGPFGSGETLMDSASGLIEAVKHIRPDLQLESVWVPDGLMKGEVVIRISRNPAPFPFLDLPTELRDRIYEYALVVGHPIVIFLETSWNPAERETSELRGGLPEILNTNARLLLASKRIYAETLPILYGSNVFRLGISRPSFVAHKFMADIDPGLQYIRTLHLAGPYAELIEACNATARLPKLEKVLIGGLHIWQRHKSRRSEEMGAQIAEDLKGWLLQIQASLGARECVVKAVDVVDFLPETDGSKIEYVTQCMIAFRTAAALYLGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBM2</accession>
    <name>A0A9Q8LBM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758762.1">
        <property type="nucleotide sequence ID" value="XM_047901557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBM2"/>
    <dbReference type="GeneID" id="71982287"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02409"/>
    <dbReference type="OrthoDB" id="3635292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="26850" checksum="CA9D9B3372141767" modified="2023-09-13" version="1">MHYPPTLRARLSTKRRDKRTFCQRLARILAHFDAHPEVWHNTLYTNKKPPPYLRLPSELRQSILSLVIDDDQILLCPRPNSDTRDLAVVDKTFAGDVRGGVARARLGEQSGREHEREQYGIDEGGEGGEGSEDDFVVKRWGGFHWRSDGNEEYNDRYFDGWNKRRQNFGTKEERKTRREEAVKAEKDKKEAVRQGLVDRAKREWEEKNPEDARLAALRASYLKRRPVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBN4</accession>
    <name>A0A9Q8LBN4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Class E vacuolar protein-sorting machinery protein hse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_03822</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STAM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758876.1">
        <property type="nucleotide sequence ID" value="XM_047902970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBN4"/>
    <dbReference type="GeneID" id="71983700"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03822"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11883">
        <property type="entry name" value="SH3_Sdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056686">
        <property type="entry name" value="DUF7784"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057827">
        <property type="entry name" value="WW_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25008">
        <property type="entry name" value="DUF7784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23518">
        <property type="entry name" value="WW_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="16" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 10" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="62"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="15">
        <location>
            <begin position="772"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="14">
        <location>
            <begin position="941"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="196"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="693"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO14510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1195" mass="133999" checksum="F79D0DBD78CFBDFE" modified="2023-09-13" version="1">MVSDCRPASPHYDQGRQPARASRERGDTHEGDISSQQSSQTRRDNYPFAPRRMSGLAGSHTGGQLYVRALYDYDADDRTSLSFRSGDIIQVITQLESGWWDGVIHGVRGWFPSNYCAVVAPPYEDGMDNTIRGDSEAEESEEEYVEQEAEHPANRVSDNNETATVNQEEAAFWIPQATPDGRLFYFNTLTGESTMELPLEAPTSANETGPRDRTNIFIPDQTRPPADFMSSGYERDDDTDYASASEAEDASLTQGSKASSHRRRRSYLSDGVSPATSMDSLSQVDPLSRSRTNLTEASNMSLSAMQQGIPPVGTTMTSFANAPTGGSSTSLLPRRFFDDAHAVPLTWNTMVEDMRRAVQRYREVVSAGERSEFVRKAEDISDHLRLLLAAGSGTTDNHSGNPSIISTNKALYPHFREMMSRFSKLVLSSHIAAADFPAPDSTQKCLHEAEGVLHGVYGFVEVARQQRGEEIPRLTPGFVMGSKTAGNWQSNGLDPRDRNGSMSFMDDEHDTSTEPTATLDAELLSRLDDLKRLIVSSIRRLDEHLVLRDKLITHHKHRQIGDAICRSGTQVIEVCRPYMSTIESVNLQPLHSPLQTPQLNDFAEHKQRFYDSTADLIVACQIVASPLGDEWAEIRGPSLEERLTRLKSVGRDLDTATNQIYFSLQLLSELIPHDSNKEHRLTDGGAPFEQQVKNKNHLRPTLADIGTSKSYSEGTNAPPPSARSAESSNSSKVERFFGQVPAANAPGRDSEEMPDYLRLDHEGEIAYDIKVDPPQLRGGTLVGLVEQLTRHDRLDSPFNNTFLLTYRSFTSAEELFELLVKRWTIQPLYGLTGQDMQTWIDKKQKPIRFRVVNILKSWMDNYWMEANDEVSQKLLQRVHTFAKDTVQSTSTPGAVPLIAAIEQRLRGQDSSNKRLVLTLNSQAPAPIIPKNMKKLKFLDIDALEFARQLTIIESKLYGKIKPTECLNKTWQKKLAPGEADPAENVKALILHSNQLTNWVAQMILTQADVKRRVVVIKHFVSIADKCRTLNNFSCLTSIISALGSAPIHRLNRTWSQVNARTTATLESMRKLMGSTKNFLEYRESLHKANPPCIPFFGIYLTDLTFIEDGIPGIIKKTQLINFAKRAKTAEVIRDIQQYQNVPYGLQSVPELQDYILRNMQSAGDVHEMYERSLQVEPREREDEKIARLLSESGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCG4</accession>
    <name>A0A9Q8LCG4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cysteine synthase 2</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cysteine synthase-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">O-acetylserine (thiol)-lyase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">O-acetylserine sulfhydrylase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_08507</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759268.1">
        <property type="nucleotide sequence ID" value="XM_047907655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCG4"/>
    <dbReference type="GeneID" id="71988385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08507"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000049">
        <property type="entry name" value="Cysteine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000096">
        <property type="entry name" value="Related to cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="17">
        <location>
            <begin position="109"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00079149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO14902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="52110" checksum="C3F61A13BBF8416D" modified="2023-09-13" version="1">MGWFLDVWQRVWESITDNRGKLTATGGFLVGIILTLTFKDLYPDLELAYQRRLRRFRGGVPHPLPGQPDYVRLEDHTNRKPSVQQEGSHDPHQLAPVVSREEEIKTGVEGLIGNTPLIRLNSLSYETGCEILAKAEFLNGAGNSPKDRVALSMITHAEEEGLLVPNRGDTIYEGTVGSTGISLASVARARGYKAHICMPDDVAIEKSDLLLKLGATVERVRPASIVDQNQFVNIARRRAQEHTDDPNKPGRGFFADQFENTANYLAHQESTGPEIYQQTTGKLDALVAGAGTGGTIAGVALALKPLMPGMQVILADPQGSGLYNKIKYGVMFSSTEAEGTRRRHQVDSIVEGIGINRLTTNFNAGMHLIDDAVKVSDEQAMKMARWLVEKEGMFVGASSAVNCVAAAVTARKLGRGKRIVTVICDSGTRHLSKFWKEAGIVGGEGVEFTLDEILDEGVKGAWRVLSGVNGTFMPCGKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCG8</accession>
    <name>A0A9Q8LCG8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759205.1">
        <property type="nucleotide sequence ID" value="XM_047907519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08371"/>
    <dbReference type="OMA" id="NQLFFHQ"/>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23413">
        <property type="entry name" value="zf_RING_Vps8_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="2">
        <location>
            <begin position="744"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="3">
        <location>
            <begin position="1287"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1533"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1878" mass="208213" checksum="68F0254A064FB738" modified="2023-09-13" version="1">MSSSPGDGHEGGNNVDMETDELARTSEARIEDERAEEDADYGDCEDAAEGGAGDPAEEELLPEAGGNGNSSSISEDIDDQDFPQLSREEGQATGSVSPEIDLDVGPSTPTPVSPLASWPDSGSIPDDTLSQRGSLASSPGRIMSSGPRKTVSRTPSGALQPFERRFETRLSASPAGSPRAQSPGFLSPQSRHISISSQLSGVSSQDGGSATDTPQAPWEVVRWRKLRKVTGQAFSESGKRSFGRPTCVAVSALIAIGTSKGLVLGFDYHETLKIIIGQGTKATECGSVTAIAISADYSTIATGHANGFILTWEINRPARPFLMIPPLDRNVLQQAQHPDGHLENCAILHIGFLGTRHTALVSADAAGMAFSHLATRGLGAVTRSIKTTRLLGRYPSAEPQVQPSKKPSSVLAFSPLPLGNVEQATDGMGLTALLTPYLLVIVSTTPIAQTQHKAPRPKELTPHSTLSGCLAWFPAVKLKSSSADAEKGNSDTKLVYCWSNVLTVLDVKVIENADPQKQPSLEFAPRSRWRADEAIVAVQWLGRSVLGVLTISQRLLIVEDVSLQVTDTIDLLHKHIYHQDLISQQLHAVVEQLNTDDPSLHGVVADAFYMSYKVYKGRTFLLGFNDLTVGILSNWADRLMALMEAGDHIAAIRLATEYYSGSANNLTIGLPATDGARHELVEERLLAMISASLNYTFAQQDSERSTRLRELAEVCFEACVMMEETDYLFADVFEYFEEADEGSVFVITLEPYVLDGEVNMLPPEVVKAVVSHFIGEAQGSRLEELLCRLDPHSFDLDQVTMLCRQHTLYDALIYIWTQALQDYVTPLIDLLTLVKMLLEGDEDEDITENLFYDSAAKTFPYLAYSLTSRQYPSGDIMDDEEGSQAKTDLYGYLFAGTPVAWPQASKKTFRTTSQSNDEPAYPYLSLLLQFDVGSFMSMLNEAFEDPFLNEAEDDSGTNGTSLTNGLTARQGYRISRQQIIEILLIVMRQGEFEPEQVVYLDMFIARSLSKYPGQLILSGTLLNSVLQRLCHPPLESLRDDCQLSVEYLLSAYHPSSVTTLIEALRKARFFRVLKSVYRSERLYTELLDTYFEDPDDKDAVFDLIKLCLRDSTGLSNKQTQSIKQVIDHHVYDLAAIDIVLTARTLAISAPDLLQSSVDALEDSHQQFIFLRALLEPSSLRAQQLSVSPLTQESQKDFTEQYVQLMCRHDPTHVADYIKVLPSSDLRLERVLPAMENSGVIDAAVALLARDGLARDAMDRLVSHMQSLQLALTSLIDAAALPEVTASEETSDDLVEDLEKYTTVGIWLCQSQSAVVTRKPRPRSNMVWDIDENDLDLDEYLWLNLVDIVVKVTQSVMEALNHFEEHPSDQAGDPFDPSKLASSLRANVQQAFTALMATTAIPSVKLKENEDAPNKPKQRADHLSFLRVLRAFLSRAASSAPSLADLRAVLQDIFSAYTFESGVLSLANELLGSDVFTEIQEANTLRQRGWRPRTQVCERCKRRAWGPGIGEIVWDEWVAREQEREADKARKMLERGGGEQARRLSRGKAKAPATPTIEREGGSEEAKKLALVVFACRHVFHRVCLDEEFREGRPLRREVYRCPSNDYFLREQGLHGDFGPCAPEPFDEQFELLPVSLEEYLAQIREALPSWLHDKYDVFLSSWRNRVPIEFHQDGEPLLVVGDDGLGCIKADAPRHRGKFRYAKRDGPTTHYFQEGPLTPGEIYALASRFVIAPDFFARNLAMGWAVSETTTHTPAAFWNDVCADESEWHMCLVPCTTVDRWDSPVYATGKSSTISCIKTADNKHHLFLVSEAIRLDFEEANRPEDCRLRAWLQSSLRPRPTPLEPNLPMWKAPSPAETQLDAFRRIAANSVKHDLKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCR0</accession>
    <name>A0A9Q8LCR0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07961</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759340.1">
        <property type="nucleotide sequence ID" value="XM_047907109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCR0"/>
    <dbReference type="GeneID" id="71987839"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07961"/>
    <dbReference type="OrthoDB" id="6017at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000083">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054551">
        <property type="entry name" value="RSC4_Ig-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22994">
        <property type="entry name" value="RSC4_Ig_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="61"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="257"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="152"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="365"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="415"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="436"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="668" mass="73130" checksum="D0D2ED42D0D59FC7" modified="2023-09-13" version="1">MDSSARKRKASASNATASEGASSKKIKLLNSNPASKQNSAPDVQQVGYKLLEYLGRATDKTGHAIAGAFLVLPPRDELPDYYQQIKLPVALDIIKKKLDQNAYPTVTTLESDMKRMIQNAKDYNLPKSEVYEDAERIRKLVYNYMKQHNPAYNDPSYTSFATPIPDGPPPLPTLKLTNGAARQTEPVKHERESRDGSVKPRHSTAPKASEPPSERKSSVAPSAAPTTGDADDESMDFTGKTFQEAQEMIIAECIRYTDDEGEAIFYPFVNLPSRKLEDYYKVIRHPVCLKMLQKRINGIHGRAPPTGVTDYKTWDAFEEETSFIWKNARVYNEDGSDMYTLAGELEEHFKSRLAEAKEKVEEPAAARIRLGGPKPPQTTAAPKSGITLNLGQHRNSPTPGVSVDNEALARQRAMVSAGVNGQQTQSRPAPHVNGMARSSSQLSNTDAPRPASNANATSPSGANVKYEKMSTLSPAPAQSTAAGAIQPITNGMMPPPVLRPTSSSPYPTAPGYPGVTSYHYTAPALLPPTPVRSYPASDALLPVVSISTHPQLSKVQYREKILPHPTLSHQSTTITLPSTHYWLQIAPTISRELSMGRAYKVFVSVNGSRMTQRDTQYHTDDGTRTHIYEGSLASGVNRIEVEVVAAKPNEEKGLDIEKVTVFANLTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDH1</accession>
    <name>A0A9Q8LDH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glyoxylase B2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759736.1">
        <property type="nucleotide sequence ID" value="XM_047907617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDH1"/>
    <dbReference type="GeneID" id="71988347"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08469"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="31375" checksum="3F452B6B797DC268" modified="2023-09-13" version="1">MDFTMDRARTDFDQCDLSSRVEVRTFVEPSTKTWQYVVIEPHGIHCVIVDPVLEHTDEQPRVSTTAADELLDFIKQRQLQVDAIFETCSQSETTRSAAWYLRMQLLVSQGYAPRICGSRATAPFNRLFSRKYGKNFRDTLENDYADGEAMAVGSMSISIVSLPGLSSPDGRAYLVEDNIFGAQPVVELQSKLEQAMKDCCYDWDSSERYHQAWLSMQKILGLPAHTRIYLSSADTGTAGEVTARRRRRPFSTVQECMPEAETVQSMADDTRALLGDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDH3</accession>
    <name>A0A9Q8LDH3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759774.1">
        <property type="nucleotide sequence ID" value="XM_047907452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDH3"/>
    <dbReference type="GeneID" id="71988182"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08304"/>
    <dbReference type="OrthoDB" id="5316527at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="423" mass="48177" checksum="F2FA69DC4A875561" modified="2023-09-13" version="1">MHRLPRAFRLRQQHLVPPRMNRLPQQRRLAHTMPNGKGEPIRYQAVRFKKPGLTMRRIATIGLYGGAIYAYLNLMAKYLDITIEKLDEMELEDEEEEGVDEEDQEGPFYADENSTFIPMTWATKQARTFYKGSDPEWQEFVKMAKDKPRQKKIHEELVQVVYKGAQQHPVIARQLGKDTKVGKYWLDLSFPDGPPPEFERSGIEIGDGYIAWSQQRITPENQWRLMRALWPQAAFNSVWATTKVLAGIQYRRTKQALGWEGKDPFSPEERYRHAVEMMEKQQAAREGKQLGKAQTEPEGNSSAVVNASTATGTNSTQATTGDGKKLPWTFNVPLPPAATTGSTDAPIALAVFQSALSQQWNPKKMEPPKGTFVVQGLVEIRGSRGRMLFDVQSCYDPKAAKYVTVRLHMRNFKRWNQAPRGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDN9</accession>
    <name>A0A9Q8LDN9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759850.1">
        <property type="nucleotide sequence ID" value="XM_047907855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDN9"/>
    <dbReference type="GeneID" id="71988585"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08707"/>
    <dbReference type="OrthoDB" id="5238236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="11"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="25333" checksum="6DC82DC4BAC81962" modified="2023-09-13" version="1">MSFNLVDRYALYKEGTNRVTRWLVGTATACRRSATAKNKSGIISTRELLQYANLIAGWKPPIEIPGNIVELIKDVVVGRKACAEFYDAQNAADAGHDAFICAPEDIGEKLRGARRSRKKEKGPAREDVSDAHQELGSKGLKAEALRNLFEHLQVEDSSEEAWRSVPVKNEVKHLIAPPKASPTLETDPEEETRFALFCSSRACSRFERSLRRPGQRLAITSSATQQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDR1</accession>
    <name>A0A9Q8LDR1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759720.1">
        <property type="nucleotide sequence ID" value="XM_047907123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDR1"/>
    <dbReference type="GeneID" id="71987853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07975"/>
    <dbReference type="OMA" id="MKMIPQP"/>
    <dbReference type="OrthoDB" id="3919589at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="814" mass="88661" checksum="A9BB9329E0E9FACB" modified="2023-09-13" version="1">MYIEARPLSTYQPTPGWSIPPLSPGKLKRPPIGSAAPTSGSSGHRSRTSLQRPQFPSSGSSSSSLCGLEQTVPSFQSFVKRTPSKDSSDKPLPPTPSLAAKFSGESLIDSYFRRSSSIYSRTPSQLDADSIPGWQIDGVTEDLPPFLLQPIAYSVSTPDLSHKNDTPPLLEPRVYSPLIISPSPTVSTITVDRVDPEPLSGISPNAGPSKSSHQSLMASKRPKAETISLEEAKQALKAPGAVPLLPEELRAQALKQRRSQGQIRLDSIDIFSVGGKAPQLPPHVDEGLRAQALKQTTSQGQIRLDSIDIFGKAPQLAPHLPPAATLIDTQGRRRTLLTPPIEVTTPAKEYPLGAKPSLPYAKAFRVGNGPVRNITPPVAHARTVSREYVGLFSHDNDSDVSRGRRRERKRSRDVDQANTLAQPYHSMLTQQQTRQASESSGWDSDDSVRARMKMIPQPLFQTKQIPGTRQPADSYGSQSSLSVPGSHRRDDSGSSASSGKRSTGFHLRLSPPTSTRASSITGMIPISPPDDHNPGRSRPPPIVTNVSGRVKTNRTTPPRSKSHFERGMRYIRSKSSKKEEQKRADDLKQSMQPGTPLLAADIVALKLRTPDSTPNTSPLANSPSTWRTTNKSNVTEKGKVPMWERVAKNVAKGRRRSSNRSQSSSQLMSPGAFVPSPDSPHLFPNPIKSTAPYLGWTDSTKNLFDEAHTPTHPPSGHNLTHIIGPPKPLDDSKNGLVDADSFGSAAGRPSIVGNVLDSWRENKAQKRRENLKRAIRVVGPEEVAPDQKVTEGQREVWSRPVLGLQRKLSEFGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDW3</accession>
    <name>A0A9Q8LDW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase family 34 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759254.1">
        <property type="nucleotide sequence ID" value="XM_047907230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDW3"/>
    <dbReference type="GeneID" id="71987960"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08082"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 34 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="41871" checksum="3E24901D52747D40" modified="2023-09-13" version="1">MASTKGSIYTVGDVESDEVHHSLARMRFIMARTSILFLFIVSLILATFEFTKMYHGMHVRIQTSSTGLETFEPTSYFFHKSTAINNRLTKLVGLNWTSPQRPTIGKCTVAHGKHNEAYQRAIDTHLAHSKVNGYTMFLLHQPILDGLWSKEAALLEVLLLQLAKPAEERLEWLMWFDADTVIINKLISLEIFLPPAHRPDVHLLFTKDWNGLNNGVFLIKVSAWSVDFVSSIVSFRTYRPEEELEFTEQSAMEKVMQMDQYKDHVVQCPSQWWNAYPNDGGEENVHFDHRPGQLLVHSAGIGDKGKVIDEWLGKLAHQRYLYAMPASGTNYKEQIEAFWRGLDEEREANDDNDTKDDPRRALWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDY5</accession>
    <name>A0A9Q8LDY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760014.1">
        <property type="nucleotide sequence ID" value="XM_047907291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDY5"/>
    <dbReference type="GeneID" id="71988021"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08143"/>
    <dbReference type="OMA" id="MAWASIG"/>
    <dbReference type="OrthoDB" id="2555959at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="66" mass="7539" checksum="DA3AB60994329137" modified="2023-09-13" version="1">MSLWQSYRTIPPRTRIFIGAGIMAYAAAGLFLSDKAEQSFGFTPTEEDKKKLRHAVPKVHMVEREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEL4</accession>
    <name>A0A9Q8LEL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760170.1">
        <property type="nucleotide sequence ID" value="XM_047903386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEL4"/>
    <dbReference type="GeneID" id="71984116"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04238"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000008">
        <property type="entry name" value="Glutamate carboxypeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="217"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="397"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="653"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="778" mass="85120" checksum="3A55B623B4124442" modified="2023-09-13" version="1">MASERTPLIEHVPVADREERYSNRKLRRACSIVLTAVPALIILLLVVGLIYGGTKGIFGGNKKKSEPDSIASSSVELPHSAWPESEGIRYSDLKQTLLDTPDAKKAREWSQYYTAGPHLAGKNLSQAEWTRDRWEEFGVHHAEVVAYDVYINYPVDAGLSMLHNGKVAYKASLEEDILPEDPTTSLEDRIPVFHGYSASGNATGQFVFGNYGTFQDYQDLIDAGVDLEGKIVIVKYGGIFRGLKVKRASELGAIGVVMYSDPGDDGEVTEKNGLETYPDGPARNPSSVQRGSCQYLSFAPGDPTTTGYASKPGVPRQSPDGKIPDIPSIPISYLEAFPILKALNGHGPNVTSFPDSWQHNLGLDYKGVKYNIGPSPENVTLNLFNQQEYTTTPLWDVIGYINGTISDEVVVIGNHRDAWIAGGAGDPNSGSAALNEVIRSFGKALKSGWKPHRSIVFASWDGEEYGLIGSTEWVEDYLPWLSGSTIAYINVDVGARGQHFTASAAPLLNKAIYEVTSEVPSPNQTVPGQTVRDTWSGHISTMGSGSDFTAFQDFAGISSIDIGFGAGPNDPVYHYHSNYDSFYWMDKFGDPGFEYHITIAKILALLAAKLVEEPIVQFNATDYGVGLEKYIDSVKSFAAEQAEISAEVFTDPFKQIDKAISYFQEASVNFDAKAENLEARLQDASTSSKHKSKLYEAIRATNTKYKFLERSFLHGAGLDSRSWFKHVVFAPGRWTGYAGATFPGLVEALEDHDGEGLKKWAGIIEGRIYAAGDLLKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEN1</accession>
    <name>A0A9Q8LEN1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08652</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759659.1">
        <property type="nucleotide sequence ID" value="XM_047907800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEN1"/>
    <dbReference type="GeneID" id="71988530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08652"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="324" mass="35270" checksum="A84FB502BAF8593C" modified="2023-09-13" version="1">MCLVDPTASSDHLHQVMSQEHLVSMADPSWDDMSTVNRWLTWAFSPAISAILVTLVVSLLSPILIHWYLYKTAVAKEPPSIILLGPSGAGKTSLLTLFANGTTSTTHTSQEPQTALCRLPDSTRSREDRFRSENDNSSPSQPTFHLVDNPGHGKLRHHATTSILSRTSVRGLLFVVDSAAVSSTAGLTEAAEYLHDILLLLQKRHTQGKTSKGPTAIPVLVAANKQDVFTSLPAALVKTKLEEEIAKVRANKSRGLMDSGVAMDNDADGDDEKNWLGEYGSKEFKFTQMDEHGVEVTVVGGNVRGNGDESGKVEEWRAWIGDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFD7</accession>
    <name>A0A9Q8LFD7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760019.1">
        <property type="nucleotide sequence ID" value="XM_047907016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFD7"/>
    <dbReference type="GeneID" id="71987746"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07868"/>
    <dbReference type="OrthoDB" id="3650886at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="58"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="470" mass="53240" checksum="0CA07BE11EF2CC82" modified="2023-09-13" version="1">MDEYSEVANIGLRHAWKVPRLSLALLEFATYINLLSPSLRTFRQPLDGHGRTFADLYQRYKIGTNRITQWLADTANDIGKLESIVDRQTRKALKHSALRGSSHTVRISTSQLVRLASEVSITTLRNRAPPKDIRDIIIITEDVLAGRRDYSVWNEQKTTTKDAEHRQQNESHQHFIHVLVEVLDHLKRAHKYSQPVVSRPKATRGKKKPSAASVAVKPDDSTVLKNIYKGLALEEPAIDSLEESTTHFELEQPEGEDLFAFWCLLKDFNKIRNFLRSIWQEYYDKKIGIHVASELSDKAYEIVQHITDDFAAEFPPLGTFSRVADRLDFEISMCDGEIESFSCSDTTSLVDGNFSVSTADFYRCHELNRRMRSLAVTTADLVQKGGGAALPKFDQFCNLLPDVFVATGDMPLHVVMIYQAMMDTIEIGVEDTMSPFASLYKEAVIVKSKWAQLEEVQALSHAGRSLFDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG42</accession>
    <name>A0A9Q8LG42_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dihydropyrimidinase</fullName>
            <ecNumber evidence="7">3.5.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16121"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="EC" id="3.5.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="8">Carbamylation allows a single lysine to coordinate two divalent metal cations.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.2" evidence="7"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761116.1">
        <property type="nucleotide sequence ID" value="XM_047903397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG42"/>
    <dbReference type="GeneID" id="71984127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04249"/>
    <dbReference type="OMA" id="WVTAEVT"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004157">
        <property type="term" value="F:dihydropyrimidinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000217">
        <property type="entry name" value="Dihydropyrimidinase-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF1">
        <property type="entry name" value="COLLAPSIN RESPONSE MEDIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="54"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611778-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="504" mass="55409" checksum="6212C6F7F7C7AA07" modified="2023-09-13" version="1">MVFDLVIKNGIIVTASEVLQDGLEIGIKNGKISCIGTDLPTSSNTEIVDAEGAYITPGGVDSHVHLAQKNSPTGDTWETGTRSAIAGGTTTVIAFASQQKADTSLWPVLEDYKKKSTGQTYCDYGFHFILTNPTPEILRDELPILAEQEGITSVKLYMTYELMKLNDREVLRILFACKSLGMTTMIHAESHDMISMIIEGLERNKNTEPYFHAVARPRIAEDEASYRAISLAELADAPMLIVHMSSDVAISHVRDAQTRLLPIHAETCPHYLFLLSEKIKAEPHDHFCGAKHVCSPPLRHDTKDLEALWQSIANGTFTTWSSDHAPSKYDHPGGKRLGLIDGVPRFSKIPNGLPGIETRVPLLFSGTPACRSQEEVRLSLPRFVQLTATNPAKLYGLDGKKGSIAPGYDADLIIWHPGNTGATTISQSIMHHDIDYTPFEGIRVGNWPRYTILRGQVVWDQAKGVTGQVGYGKYLKRGKGQVLVGKTGNVPRGMKPEERGCWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGL9</accession>
    <name>A0A9Q8LGL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrotransposon-derived protein PEG10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGL9"/>
    <dbReference type="OrthoDB" id="5088132at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="22698" checksum="EC8353550393F4FB" modified="2023-09-13" version="1">MQDLRAAFGDPDRRATAQNAIHNLLQKNKSFAEYLAAFNRDIGFTGYNEETKKSTLRRGLSAELLRALEDKDVGAMSFRELVETCQRLDSNMKHTASLLASRSQGRQPRGPGSHFAAPLGAAAPTALPPVSVGDAMDLSAGAAVPRVQGLVNGKLTPEEKLRRRQAGLCTYCGGPGHIAANCPQLAARNARNPVRGAVGAIEPATAAPAEQEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGT7</accession>
    <name>A0A9Q8LGT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rieske 2Fe-2S iron-sulfur protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05977</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761591.1">
        <property type="nucleotide sequence ID" value="XM_047905125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGT7"/>
    <dbReference type="GeneID" id="71985855"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05977"/>
    <dbReference type="OMA" id="WDCPVHG"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03477">
        <property type="entry name" value="Rieske_YhfW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000014">
        <property type="entry name" value="Oxidoreductase, FAD dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038010">
        <property type="entry name" value="YhfW_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF281">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="442"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="60373" checksum="9764B29C34828E2A" modified="2023-09-13" version="1">MATVSENPPQPAADYFNATSGATEPVWVHTEPYSARPHFSKLERDVETDVCVVGAGIAGIQTSYELVTRGFNVVLLEAREILSGETGRTSGHLASALDDGYTLIAGKHGQEGAQIAADSHQWAINRVGDVAKKLGIDCEYRLLPGYEFSQYDRVKQPKEHAEENKELEEEVSKAQELGLKVEYDADFKLRGWDGEPDQRGAAIFRDQATFHPTKYLNGVLKWLKEQPNFHCFTHTRVMDFSEKGIEIGPIGHKTVELKTIDGYTVKAQDAIEYDRTYCIAIKVPKGYVEDALFYDEAEEYKYVRLTHCDAEHDYLVVGGCDHKEEPLGRFKELETWTRERFTKAGSVDYAWSGQVFEPVDFMAFIGRDPGTKHTWIMTGDSGNGLTHFVLGADIIATEISGQAHPWSKLYRPNRVASILKSGKQMLSHDLQINAQYKRFFQSDIEDIADLPNGEGGVLNPTTKTPTAVYKDDEGNVHKLSALCPHLKGVVCWNRTEKSWDCPVHGSRFSKDGVCVMGPAKGNLSPFDENAKQEQAKTGIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGW5</accession>
    <name>A0A9Q8LGW5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761593.1">
        <property type="nucleotide sequence ID" value="XM_047904959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGW5"/>
    <dbReference type="GeneID" id="71985689"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05811"/>
    <dbReference type="OMA" id="RHENAER"/>
    <dbReference type="OrthoDB" id="5416609at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="356" mass="39487" checksum="B9A52BAB49AAA85E" modified="2023-09-13" version="1">MDDSRHENAERPGDSRVTLSALLERAYVFQITDPRDKVYALLGLGPRWAQQVITVDYNSELSAVYKQTTRAILEQDHALAPWSRAGLSYQRQQDLPSWVADWSSFFPHCQYSSETLGIPDRASGDSQVDVQWPFADDDSNLQTKSYKVATISQVGQKVIEKRAYSDQTFAPHELVAEAAHVLVMRTSLPLGETDTLDAFLRIWIGDHTGIIPTIPAPKSALEASNTLLLDQMLAANNEDVAAVAGDNFCLREMLLLYLETAQRPKSEVYTTPLPYAALIANRRFFITAEGYFGLGPLSTLPGDDVHIVSGGKTPYIIRPLEAPDGHALVSDAYVQELMAGEALESPGFRWQDLFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHA0</accession>
    <name>A0A9Q8LHA0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761520.1">
        <property type="nucleotide sequence ID" value="XM_047903806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHA0"/>
    <dbReference type="GeneID" id="71984536"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04658"/>
    <dbReference type="OMA" id="IPIEHRY"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BLL6449 PROTEIN"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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            <end position="60"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="14"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="32351" checksum="1C7417CC04FE4616" modified="2023-09-13" version="1">MSTQTNTQTQQKFGVSNDIPIPRGEAHSKLVFYAPPADGSAPWNYVEQPPEGSPQRNYTEDSHEVTINDIRGREQDFDMNVNGFGTISGIESKEKDFTEDESIKANYYPEVEKLVLDHVPGAKRVFIFDHTVRRSDPNAKRAPVNRAHIDQTTRSANMRVDYHMGDEAEELKNGRVRLINVWRPLNGPVVASPLAYADSRSVPDDDIVPVEHRYPHRTGETAGVKYTNNGKWYYWSGMKNDERILLQCYDSEDGARTPHSAFVDPRTQADWPGRESIEVRTLVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI1</accession>
    <name>A0A9Q8LHI1_PASFU</name>
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            <fullName evidence="3 6">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
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        <name evidence="9" type="ORF">CLAFUR5_05390</name>
    </gene>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
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        <text evidence="6">Component of the GINS complex.</text>
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        <subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="178" mass="19341" checksum="51603ACD85639011" modified="2023-09-13" version="1">MASKYYDPDAILTEAQKAPCTFELTVPELSALNAGSTVEVGTKLDLPLWLAEMLAMSKPAGPSSSLASMDVPSALGPKVMAALAAGPKSVDIRAQAQWFYGMGERILNLFDDEELADVLSKTFRERALEIADKAQNTRSMGEGDEFMRGLERSERELFRAAHEGNAAVKKWSVTSSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHJ1</accession>
    <name>A0A9Q8LHJ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoprotein TPR/MLP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904646.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71985376"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05498"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057577">
        <property type="entry name" value="Nucleoprot-TPR/MLP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25481">
        <property type="entry name" value="Nucleoprot-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MPL1" evidence="7">
        <location>
            <begin position="192"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="8">
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            <end position="596"/>
        </location>
    </feature>
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            <end position="1204"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="1208"/>
        </location>
    </feature>
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        <location>
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            <end position="1669"/>
        </location>
    </feature>
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        <location>
            <begin position="1694"/>
            <end position="1729"/>
        </location>
    </feature>
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        <location>
            <begin position="1790"/>
            <end position="1883"/>
        </location>
    </feature>
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        <location>
            <begin position="1275"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
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            <end position="1911"/>
        </location>
    </feature>
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        <location>
            <begin position="1944"/>
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        </location>
    </feature>
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        <location>
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            <end position="2008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2040"/>
            <end position="2064"/>
        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF25481"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17569.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2101" mass="234799" checksum="D41F1A95B096A903" modified="2023-09-13" version="1">MRTRAQAHDPSALDVAYLATTYGVEEAELHALIDAPTTELVRDFLATITGKGEEFDKLNADKLKVEVELENTVRTSDTKVKAQKAAVTRQTKEIDDLRTKLNEAETAREALASELEKLRSSSTGSSAETQTLRQRLETLEASNRDALALVESKSTEKDRVATELSEQHSKLLALRREISQLEERNQSLENATSSQKFKEQSLQQEIDLLKRNNEWHSNELQTRNQEHAKFRKERNARISTLERELQDSTSNVEGLKRTESTLRQRLDEVQGKADEAFARIATLQEEAARKEQDFRTELSGSKRLSELQAQNAATHKARLAEVQSELEQVREDTHDEVSRLQAEIETERMDKQDAEQKVAELELKVEDLEQQVRTARPSTPVRNGSPTPGTPNALSGSLRKTVNGLSFTQLYTRYTEAQEELAAERRRTDKLSTALDEIVHDMETRKPEFEDLRAEQTRLEGEVLNYSDMLESANKERDQARQEVEVWQAKANAAEVEGDVLRQQLRDLSAQVKVLLVEVSSRDQGLGELSADERLEFERAARGELEEGVLESMTDTGRIIQERFVIFRNVDEMYSKYKEQLQATRNLAERMEGAEALEKARQFEATAAEVEDLRRQVARYKDELEQTDKSVQSFMKERDMFRRMLQHRGQLAPDADLQSMFGQSVGPGTPSRNSMAPPATPRSKETEDLNKLLKEQQTFFDQYRNESSTDRRILKEQVDALARDKSTLQANIARAQSQLTLATERYEMLQSNFNALRSENGEMQKRSQQLAEQAAKQDLRTQQVAEELVEARSMTESLRNENANARAEKELWKRIEARLTDDNRTLMDERSRLNKLVTDLQNLQNERELSESESRRRLQSRVESLENELSETKKKYEAEVEESRKAALRREYDESQNRTRIDDLVKSLGNTREELAAAKTARDSLQVRVDEMKIELRSAEEKVTALQPRPTPRLEPSQNGEQRLNGDEDVPAEQRLALEVADLRRELDLTKTELESAKQQVEEYKKIAQSAEDELASFSETADKYKEDTESHLAERNTKIRELEKRVDELSTELSQSNSELSDLRGKIEDHTRVLEQHRTAHESELKRAQDYADEQRAAYEAVTENVQAQADIAKDAQANYDAELIKHAEATKALTAVRKEYNDLRLEIAGLKAEAEVAKASLERGEESWAEQRERFEQELEEAKRKRRDLDEQNKILHQNLESFSNELAALRQGRAAEGEARESAPTGSGEGNFQEVIKFLRREKEIVDVQYELVSQEAKRLQQQLDYANSQLDESRQKLADERRQTADRANAEGSTNKLMQTINELNTYRESNSVLRNDLAQVRNQLKEKAEQAEQLLAEMEPLKGRVGELEGELENKEGEMKLLLDDRDHWRERTQNIISKYDRVDPAEIEAMKKQIEDLNAEKQRLESEQAPLREKVEGIDALIAEERENAQKDKKQAREGFVAQAKEQDRKRRVEIQELRTQKEDLSTELTQVKADLEALNTELASTKTLLEESQEASAAKAQTGDAEEGQIQEDGSAATGEDHAALHNRIASAEAAASEHASRAEFLNNHVQTLQARVQELEGQVADLHKQLSDAQVTTTGAPTENAAALEQLQQELTNAQHEVQTLRATAQAAPAQTLVNAEPAPGEKSVADQVAEEVAQLRTDMEKQHELAKQEMEKTCQERINKQRESFSKQMLERSNKIKADMQQEHTAEIQRIKEEHNAAIDKLKADHQAELDRLSQQGSAAIDKADSEAVVKIEAMAAESDFSKLELTDKQVKDLVRVHEGIKALVTRSIKSNVEKQTATLNESVESKKAEIAELKQKIEALSPGETGEITESDKVSRAELEQQLELLRKEKDEAVAQAQEQARIDQEAAVKQARQNAEQTAEKKSVLQKRFLATASAKVQIVQQAAEKTPTKPVKEVWDVASKAQGAPPTQAKQDVPPSPSQAKPAGTLGQPQQSSSPAPNPQAAAFTPSSSMTAASAPTASAPAPKAPAAAGAGPAALRANAQSGIPQPGSAASGSKLPRAGGPPSRQASIGGPGGVQIQGAAGAQRGGGATGLPRGGGPFTRGGRGGSRGAATAANAGQKRQHDGASPAGGDNKRTRGGPPSGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIQ2</accession>
    <name>A0A9Q8LIQ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_06008</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762481.1">
        <property type="nucleotide sequence ID" value="XM_047905156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIQ2"/>
    <dbReference type="GeneID" id="71985886"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06008"/>
    <dbReference type="OMA" id="NVPMTLN"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="96"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="282"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO18115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="47369" checksum="CD8A4EECBC2E3491" modified="2023-09-13" version="1">MTNDEERGINGAPREESNEETPLITRGASSLGNMASGRVRKNSNGQPLHEDERAWVRYPSNFLRLTWATLASNYVNVLLVCVPAGIVLGAMGANPTAVFVVNFFAIVPLAALLSFATEELSVKLGQTIGGLMNATFGNAVELIVSIVALYKGEIRIVQASMLGSILSNILLVLGCCFISSGIRRGESRFNETVASTMSSLMAVAATSLIIPATMYAALTRSTADSDGNILVLSRGTAIIMLILYVLYLVFQLKTHAHLFDAEGQDEEGGEQKEPEILGPVAATVALVLVTILVAVCAEYLVDSIDSIVASSGISKTFIGLILLPIVGNAAEHVTAVVVAYKDKMDLAVGVAIGSSMQIALFVTPFLVILGWIIGQPMSLHFQGFETVVFFLSVLVVNYLIQDGKSNYLEGCMCLGTYIIIALAFWVYPEDAGDIGELVSGFFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJB9</accession>
    <name>A0A9Q8LJB9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase type-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762570.1">
        <property type="nucleotide sequence ID" value="XM_047904979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJB9"/>
    <dbReference type="GeneID" id="71985709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05831"/>
    <dbReference type="OMA" id="RHIFEND"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="262" mass="28138" checksum="26574231B32CCED4" modified="2023-09-13" version="1">MQIKDSTFIITGGASGLGLATVEDLYSNGGYTAILDMNPANGEKVIKSLGERAKFFEVDVTESESLEKAINGAVEWAKQNGKPVRGVMPFAGVGLPGKIIDKNLNPIAMEKLDFVIDINLRGVLNTLRLVVPHIAKNDPVNEDGERGVIVMVSSTSAFEGQVGQLSYVATKGAIRSMTLVLARDLAPNGIRALSVAPSLFSTAMSAQMSDKVRKALENTAEFPKRLGHAKEFAHMVRTCVENGYLNGECIRIDAATRMPAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2H2</accession>
    <name>A0A9Q8P2H2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fusarisetin A cluster transcription factor fsa6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755135.1">
        <property type="nucleotide sequence ID" value="XM_047900473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2H2"/>
    <dbReference type="GeneID" id="71981203"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01325"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO10769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="65225" checksum="732CDD5AC6AEF538" modified="2023-09-13" version="1">MASVVKKRTITRARETLTCNPCRSRKLKCDKDIPCSSCTKRGEAEACSYAKRPVRKEHADQSKTARAEERLQHLGDLLEIYASSGAVNNVTSHTEEDESSTCTNGSATYIGATHFSAMLDDIEWLRQYLRHRVRESSIRLTFLFGGTPRLPLQVVLANHLPPKIEVDRRLAAYFRAEAIAAPCIHTPHFKRHLFSILDLFRGVGRARLYDESPDEGHKHNFSLAATHCLAIGRYSRPQPLAVEALAVYIQAKVIVTLDPLHMPWAITVGYYREPDNFKLLTAFEGEMRRKTWSFAMQLDLLISFQLGLPNNVQFGSWDTRPPSNLKDEDFDEDSAVLPPPRPAHEPTKTTFYTAKHMLMTVFDKILKYALAAGSIRSEEELIALDAEGFQARYETLPAVLHYRSISTSLTDPAYIKCRCVLHRKHVTTGRLESIRVRFEAASQIVGAFFWEMYPELKPGGQFYDDRWLLGSITGNDYLLAVMVLCLLMCQSRRAAVPGLTQEELQSKADVSIAARRTRRIFEAMLSPCQGATANGTGTMQSDIDFTQSWNDPWSNMFDTHEWAFLEESLNSNFETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2J2</accession>
    <name>A0A9Q8P2J2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755344.1">
        <property type="nucleotide sequence ID" value="XM_047900870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2J2"/>
    <dbReference type="GeneID" id="71981600"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01722"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="4">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO10978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="37827" checksum="3908EA01A760AF53" modified="2023-09-13" version="1">MSRPTSINAPGAYTTCDPYHMFYDDDDKCGPDNHYRCPKKKCCGKNGKCGTGEDYCGAGCQLGWSDCWNSSTTCKVLNQDKDKDKDDDDDDHLIPIFPLWHERPDPPGPPPTINIEFGEIRFPKPPTIDWIKIIGGDFDCGWLGCDGITGWFLKLIPIRIKPCNPITKMLCRLLRLNCCPKKDKNNDKDKDCVGCDPPPSITGLFGDSKICDEPMDKCEDLEPENDEGDEDCTSTSTAVDKTVFCEVMTATNGGASETCTSTASETRSGCTLAPATTTTVTSTACGTVTASQISEYCTVITAGSSTVTTACPSTITNKVTGCDATAESTSIRRHRSQHDDNLLSADSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2U0</accession>
    <name>A0A9Q8P2U0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-activating enzyme 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755465.1">
        <property type="nucleotide sequence ID" value="XM_047899506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2U0"/>
    <dbReference type="GeneID" id="71980236"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00358"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000008">
        <property type="entry name" value="2,3-dihydroxybenzoate-AMP ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="52"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="498"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="66110" checksum="21A79BDB3F00BFE1" modified="2023-09-13" version="1">MSSAMKRLSNLAAHFVPSSSSPTAADNSAMKDSYQHSHHIHQLSPTFFLPRAASIEPDAIATYHKTANAKILQRTYQETADRARGLAYYLKKHGFKRVGILCTNTPAFLESIYGIGGAGAVNVAINYRLKMEDITYIFDHAEVDLIIVDAEFRSLLDDFKQSHPNVPFIIDTDTDEDTGEFDQCVLEGIQHDDRNGGRGWAGLETEVPQEDSMVAIAYTSGTTSRPKGVEYTHRSAYLATLGNVIESVLNTAHPKAQRCHYLWTLPMFHAMGWTFPWAVTAVRGTHYCLRKIDYPYIWQLLKEQHISHYNAAPTVNTLLLADPNAEKLEHPVRVTVAASPPSAHLFESMETHNLRPVHVYGLTETYGPITKGYLMPQWEDLPVKEKYAKMARQGHGFITSLPARVIKTNQDESGSLDASEKIEDVEKNGKEIGEIVFIGNICAKGYYKDPVATRKLFAGGVQHSGDLAVWHPDGAIQIMDRAKDIIISGGENISSVALEGLLMTHPDILEAACVAVQDKKWGEVPKAFITVKQGKKGGMTGQDVIEWAREQSQISRFMVPKEVEILDELPKTSTGKLRKNVLRDWAKGKKREAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P350</accession>
    <name>A0A9Q8P350_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Scytalone dehydratase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755991.1">
        <property type="nucleotide sequence ID" value="XM_047899154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P350"/>
    <dbReference type="GeneID" id="71979884"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00006"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058329">
        <property type="entry name" value="Arp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26053">
        <property type="entry name" value="DUF8016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040309462" evidence="1">
        <location>
            <begin position="22"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Scytalone dehydratase-like protein Arp1 N-terminal" evidence="3">
        <location>
            <begin position="50"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="191"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="259"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="64862" checksum="226A68A80AEE3373" modified="2023-09-13" version="1">MLTFMRTTIGLSLFLASGAAAISTTGRTATLNGIQYYIPSEATGHIDISSTALTVGDGLLPLTVASTNASSFEVNELEALIEKYAEDDVWQEVFLEALYVQSSKSRIYNTTLESGVNQTTAVVASNSNAILPNGPYFVTASGSLYQAYRLYPDTQGAFVSACIGSGDGYHNLPAGQFDSSLAVAVPSRLSYTRTSGKPLAGVRIGIKDIYDIKGLRTSNGNRAWQQFYPVANETAIAVQNLVDAGAIVVGKRKTNRYQDPSSSSAGPAAGEASYDWLDITLGSENGGSIRSPVQYNGIFGNRPSHGLVSLDNVMPLSPSFDTAGLFARDPSLWRTALHALYRSNITSTPSFPSQILTIGFPAAIQSNLDATYFDFLHNHTTFLSANTTTFNLTTSWASTDPSGPSFNVYINNTYDQITAKDQATLVRNPFYADYAAAHEGRVPFVNPSPLDRWAVGDNTTETAYREALVNKETFAAWLDEEVLPADEASCSKYLMVYIPRIPAPKYRNAYLKGVTPPSAFSTSRISPMGGVPDCVVPIGEVEYWSDITRRTEYLPVSVDFMARRGCDGLIVDLVEALYQRGIVREVKTGRSLVAGGETLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3S3</accession>
    <name>A0A9Q8P3S3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756353.1">
        <property type="nucleotide sequence ID" value="XM_047899590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3S3"/>
    <dbReference type="GeneID" id="71980320"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00442"/>
    <dbReference type="OrthoDB" id="3648210at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="27639" checksum="C513DA8EC3F5BE05" modified="2023-09-13" version="1">MQNTTNQSVVADDASQSIDEGVYIQENGDQVAVPAPASLKKNKKKAHKPMNAAEQVASMAMLQEKLKLFEKVGATAARPVDTTAEVPVAVESPTTPEPVVKKRKVSDVRALSSDMPTPEAIPAAVPPAINTASPKSVATSRRRGSSIASRSSEQEDPYCPNKVKQLMDKLNGLGIGMEKAISEVISRAKKLVVGEGAEAIRDRLTELEKEWKMGNREHMQNLVKFSERNGIVAMGGVQVPSGSLDVPVQSEVVSNSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P462</accession>
    <name>A0A9Q8P462_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756847.1">
        <property type="nucleotide sequence ID" value="XM_047899272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P462"/>
    <dbReference type="GeneID" id="71980002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00124"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="12835" checksum="86FF6B3B1613C119" modified="2023-09-13" version="1">MGFLAISDDCDCLAALAQRMIDGARLRRTWITTTGDIGFRWIEGLQLCSENTVSAAADDWDLGIGTFVMTQESPKFESSLNGARMRAMQHRNRTRGEASSRAASFVLVSTDTRAKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P504</accession>
    <name>A0A9Q8P504_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757747.1">
        <property type="nucleotide sequence ID" value="XM_047902929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P504"/>
    <dbReference type="GeneID" id="71983659"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03781"/>
    <dbReference type="OMA" id="SEILMGW"/>
    <dbReference type="OrthoDB" id="2016523at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22189">
        <property type="entry name" value="PGAP4-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029675">
        <property type="entry name" value="PGAP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31410:SF1">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31410">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47277" checksum="F0D92C67DD5057B5" modified="2023-09-13" version="1">MMQQPKWLHASGTEQKSRMTTKVVLFIFATVYIAAVVVLRNLAWRDPTSKFFNPDAAYLPQYSEVRWYQTEKFLANATSSSLDHYSASNTTLPELCIGVPTVARKGAQYLRTALGSLLEGLRVSERNRINLIVFIAELDPADHPAYRKPWLTELVDTTLLYDLPTDELQRLGNMDDQHKSAFDYRYLLNACHATGAPYVALIEDDVLASSGWLRRTMAGLDRITSKITTSEWLYLRLFYTETYFGWNDGDLFEHVAWSLLLIASVALSLLATHLFAPKSRAYISNILVISLCCICAPLCITLFFLAGRVTIFPFANGVHKMDKYGCCSQGLVFNRPEIPALLDMLSGESGLFFDMRVEQYADEHGLDRWALQPPVLQHMGIKSSSDGGLKSKNARKVWSFAFERTKDNRGPENEELRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5L3</accession>
    <name>A0A9Q8P5L3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sterigmatocystin biosynthesis peroxidase stcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758392.1">
        <property type="nucleotide sequence ID" value="XM_047901650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5L3"/>
    <dbReference type="GeneID" id="71982380"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02502"/>
    <dbReference type="OMA" id="NFAPTFC"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF18">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="49"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="30921" checksum="FC39C195CE98029B" modified="2023-09-13" version="1">MGILEKLGGVAVDLSVMAWDNAIFIANLLTPKLKEGTVVPKGAPGHNLTWPEYVPPTEGDSRSACPMLNAMANHGILPHDGKNITFKDLNQKVRETFNFASSFCFFVPNFSARFLNKSYSTDRFDLEDLSMHSDKAIEHDASLTRQDAALVKDQSKPDLKLVHDLLKEASGKTPDGYPLMTKADLSRALSKRRADARKSNREYSESFFHNMFGSANSATMLTIFGGRIEDLGPMLTEERFSEHWEPRVLDRYGLTMAKFNGTVLPVEMKIDPKKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5P7</accession>
    <name>A0A9Q8P5P7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Trafficking protein particle complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02822</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758525.1">
        <property type="nucleotide sequence ID" value="XM_047901970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71982700"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02822"/>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055505">
        <property type="entry name" value="DUF7077"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056916">
        <property type="entry name" value="NTS_TR130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022233">
        <property type="entry name" value="TRAPPC10/Trs130_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23274">
        <property type="entry name" value="DUF7077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24967">
        <property type="entry name" value="NTS_TR130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12584">
        <property type="entry name" value="TRAPPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24965">
        <property type="entry name" value="TRS130_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Trs130 NTS" evidence="8">
        <location>
            <begin position="649"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7077" evidence="7">
        <location>
            <begin position="950"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 C-terminal" evidence="5">
        <location>
            <begin position="1280"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="505"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1477" mass="163240" checksum="AE90F5D71C5A3428" modified="2023-09-13" version="1">MDSSSKVTVEYHDASGVFPLVSRDILQRLPLRNLNWQSLNRPLRQIKSLHVDFVPDKETVAALRPTTSRNDSNGPNSFDIVGGGGDAKKDAVKTRKHQIPGFRTSPYLKIYVLRCDDKENYKDSARKQIRDWVRENAQPVGKTDHDAFEWMLLHVVVPDTVAASEPRWREGTKDPDELKERKAGAKLTIGKSTRTVFDRLRADFNDTGKRGVDRVAQIRIPKDRAPADLLPTPAVAETHEENADEQQKTWNDWTGKLKNLILGPFDRRVRQYEADIAEQETRRSMPGWNFCTFFIHKEGLAKALESIGLVEDALAIYDELSLGLEVVLRDIAAGQTEGAATSFAAYTDDIKERIVGTPPNATNGTHNDITNDKQDTASLFSKDYRERIVRSNISTFDFLCYLFSRQKALILRLANARAIRIQLDATADKEGGEDLVLTSEVCWRASNFIHNAARALRQDLLARAEHESNFDLRVEMESIVSSWTWAVAGLVLHETAAPALEAITTAQATDQPNGKTRRPTLTMGLGANVHPQRTSSLPTNKLKPEESQLASTAMRADDHSRTRPQTSTGVEAGQPNALPGQAELATYRAELIVTRRKMLEQLARLQGWHAGWSGAKQSRICKRSSVKLEDKDTNAKAELSSKGDVAHALHALSPSLQSALSDKDSFEAVYERLTNFAIRHYYAATLSKPAETLLGDIALLKCQQKDYEQAASCFKHIIPLMATDGWNLSEVEALKAYCQCLKSLQRAEDYVRHGLTILAKVAVRNKDQARLHPRAVAGLGSAQDVPLDLADLFADLASATEGLQQDVVSPLQNFFSNVKLDTQVIHHADGDGFSLNFSVQHVLGGECEIGEITTRLVNHEDAAHEVLLRSRGPVILQPGLNQVELVANAVTHGPYLIDKIMFRTQKLCFVEELRPPPQPTALGFTEANPPTVTIREHERAPPFVFLYPLPRAFNADLRRAKNIHVDKPRHFEIRLDSAENDISSLDIKLRPTSAGLRIHLADAVAQGVELLTAEASKPGQISLGSISAATSALITIPYTVENANRDAALRLEIDYHTAGGTHTFLKSLTVPNELPLDVDVNDMFHLDCLFSSFTVRTTTPKPFTVLGAMLDGSAVFAVEAPPALPLPLTVFRSQPLSLVYKITRKESIASNVLKQGAALSLVVRYQPTDELLLGCIRRSFVNDLKDSEHGRYIRLLEPILSQRLRLFLKAVDLETTALLGESDLPSFGAIGWAEILNTLPETVRRPLTAWLEHWHSSRQTVDIFTDEVDSLETQSITISVDVPNLDMVFATSLDLSVKVPAAGPPILVLGQPVEAVVRIRSTSQWSAKNIFPSVPTFTLQGEEETKTAFVCDVGVDSDAWILGGKRRSHFTPSNGEEWSFKVLLIPLRAGVCSLPTVEVQHDSADPEANAEDVAVSVTCETHYESAGQVVHVIHDRRTTKVHIAESSGAMLLPSSGTRPSDQVSSCPDLCDHFLHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7A4</accession>
    <name>A0A9Q8P7A4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.176" evidence="1"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760265.1">
        <property type="nucleotide sequence ID" value="XM_047903589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7A4"/>
    <dbReference type="GeneID" id="71984319"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04441"/>
    <dbReference type="OMA" id="SMTQFGQ"/>
    <dbReference type="OrthoDB" id="542135at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SCP-x_thiolase"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="459" mass="50085" checksum="B1175FBCE283D612" modified="2023-09-13" version="1">MEIKKPQQNAYVLGVGVTKFIKPRQTRSYVEMGFEAGVKAMLDAQITYDDVEMGVACFCYGDTCSGQRVFYQFGMSGIPIYNTNNACATGSTGLHMARTLVRSGAADCIMVIGFEQMQPGSIKSGWNDRPSPMELSSKMIEEEYGKHDSPRNAQYFANAGREYIEKYGANEDDFAEIGRISHEHSTRNPYAQFQQEYSLKDIKDSTMIHWPVTKLQCSPTSDGSGSAVIVSERFLKARPHLMSQAILMAGQQLQTDPPTLYSKSAMDLCGFGMTKNAVQLAYKEAGVTAKDIAVCELHDCFSANELILLEGLGFAGKGKAHEMVRNGDITYGGKGPIVNPSGGLISKGHPLGATGLAQCAELTWQLRGWANTRHVPAKVALQHNLGLGGCVVINVYKRADGKENQKLSDQQAIKGTNWTYNPATAAKTPSMAEAKKVLSKKFGVEYALSNTPQLIQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7I7</accession>
    <name>A0A9Q8P7I7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7I7"/>
    <dbReference type="GeneID" id="71984708"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04830"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="26655" checksum="2ABCC2FA29EF67D5" modified="2023-09-13" version="1">MPGDMEDRPAEENDVNGDLRPTTDAGALETSPGNSRPLTADTQQTQAVLEQRADALVLSVNHKLPFTTEFVAISDKTAVSEQLSILRIAKDRLAGRIARHSKYMPGLKEYIKSLEVIMSLLDNVAPTSTSTTAPNEALANGDSAILEKMHQDLAMLKRPEVLKLIRTNTEARRVTLTQDIAAKSAETTARTESWETETGGVEDVVSISRLTDEMEALKVERSFSRGIVALAESCPAKLEGLSYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P896</accession>
    <name>A0A9Q8P896_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CTP-dependent diacylglycerol kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761123.1">
        <property type="nucleotide sequence ID" value="XM_047903393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P896"/>
    <dbReference type="GeneID" id="71984123"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04245"/>
    <dbReference type="OMA" id="NYWREMS"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303:SF1">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="412" mass="44980" checksum="2D165B9F132D422A" modified="2023-09-13" version="1">MSQYQQVPNTPRVISPSPTPSEQSGKDGYFAPTTRSKAQRKSSVDPIQEHVGDHEEDPDLARARSRSRSPHLGRRTTRDLRMTMNGDVSSSAKTNTTKTDNAAKPMRRKTDELKVTNGAPKGGDANGFLSPADAYPKGFGSAYWRNLSRSPSPLGLIPIHREWRAFVHKHEVPRKVLHVSIGFVTLWLYSAGAQKDQIHPMLLGILIPILSADLIRFRWPEFNRFYIRVLGPFMRESEAHDQFNGVISYVAGLWAAMYFCKKDVAVVSVLLLSWCDTAASTFGRLWGKYTPRIRRGKSLAGSLAAFTFGVGSAVLFWGLVAPNTPKAVNTGINSFAFDGTLTLPLYLRDSFGLSEEQASISGSTALGVVSLASGFVASASEAIDLWGLDDNLTIPILCGIGLGAFLWAFGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8E4</accession>
    <name>A0A9Q8P8E4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761288.1">
        <property type="nucleotide sequence ID" value="XM_047903865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8E4"/>
    <dbReference type="GeneID" id="71984595"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04717"/>
    <dbReference type="OMA" id="YCLQKNW"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <begin position="39"/>
            <end position="268"/>
        </location>
    </feature>
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        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="31634" checksum="A8B9951610D898DF" modified="2023-09-13" version="1">MAKSLSLRSTLKLKSGAELPQLGFGVWDSPNHLTTKSCLEALQVGYRHIDTAQVYGNEAEVGEAIKKSDVPRKDLFITSKVLAAEGDEEATYQKCLESVKKIDGDNGYLDLLLIHNGQAQGAKGIKALWPVMEKLHQEGKLKSIGVSNTGVGLIESMKEYAKVWPPHVNQLELHPWCQQREVVDYCHKNGIAVEAYCPLVRNKRADDKTLKSIAEKHGKSTAQVLLRYCLQKAWAPLPKSDNPDRIAQNANIYDFALSDEDVQSLDDVGEKEAEALVVAVDNKKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9C8</accession>
    <name>A0A9Q8P9C8_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9C8"/>
    <dbReference type="GeneID" id="71986081"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06203"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="22015" checksum="5DE10328A73FE504" modified="2023-09-13" version="1">MDEQQDDETSSESRPPSPFAGEAAEGDHDVQMMWIKVGDDKAVEVINKIRTLSTKQVFTHYSCPRVFKGTRFARTPLPEGVAQQLMHMGGTKLRAALGALFEKYKYPGADDEQFMQQAINGSAGVANSVVEKFCLPRPSQLTDNQEVLRQYQPHRAPTAEEAYAIAALLPVTEREALEAEVTRYRDEMNALGDEEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA06</accession>
    <name>A0A9Q8PA06_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactobacillus shifted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA06"/>
    <dbReference type="GeneID" id="71987326"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07448"/>
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    <dbReference type="OrthoDB" id="307899at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000003">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="129"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
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        <location>
            <begin position="68"/>
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        <location>
            <begin position="178"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="222" mass="24524" checksum="22CC94392ABA0481" modified="2023-09-13" version="1">MLQRSARRLVPALSRRTVAVRQYSTPPDNPIPANDPNAKERNPPISGTKNLPTVSMGSRDAALMETAAEGEDKRVQQAPNRATTWSRSQRERAKAMVGPRFEQTIMEDQPRPLAAIELIHQQPVNWTKQRVVSCDGGGGPLGHPRIFINVDKPQICFCTYCGLPFAHEHHRKHLQSLPHTSYPLEPQSNAAEIPASQMAELGGKTGSDSKLQSVTGKVLEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB13</accession>
    <name>A0A9Q8PB13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase domain-containing protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763554.1">
        <property type="nucleotide sequence ID" value="XM_047906603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB13"/>
    <dbReference type="GeneID" id="71987333"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07455"/>
    <dbReference type="OMA" id="WTRLVRY"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF100">
        <property type="entry name" value="FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G01490)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="83"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="31684" checksum="ACC6CBC19EFD6D73" modified="2023-09-13" version="1">MSTGDLVPWNRLVRFVSATDGQKKFGEPIVSSPDADIAALARSGSLEVVVLHGDDPLSAQPTDKRDKVQKLLGPLRVSDVPIIRCIGLNYKTHIKETRRALPEVPTVFTKPAPSIADHDAAIPIPKIAQQQCDYEGELTVLIGRDAKDVSVADALSVVAAYTVGNDVSARDWQREPGKAGVVPQWSFSKSFDKYAPLGPVLVAQKLLGAADQQELTTRVNGAVRQSGSTGDLCHGVQELVAFCSQGQTLQRGSLIMTGTPGGVGLFMKPPTFLQDGDEVEVEVSGIGKLRNTMTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBJ0</accession>
    <name>A0A9Q8PBJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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        <location>
            <begin position="21"/>
            <end position="46"/>
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            <begin position="47"/>
            <end position="56"/>
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            <dbReference type="EMBL" id="UJO19445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="29498" checksum="8F90EA06A77372AA" modified="2023-09-13" version="1">MDATKAEQQDVSNALRREHRHQIDAEELRRRLEQVSTRQAEEESHSHATSKASAKSPAEEALDDPPSRLMALPSELRLLVYEHYLKLQLPHENPRLLLHGRAEKTSVRVLPLLAVSTQVRAEFLPLWASRITFVLGPERNASYQGECLDVLRDTVLPHIRKFCLTRVTEGYHWLITLKGARAADCSIMPDSYFHEGAFKVNCMADDSRAAMEDFLRDISRHRSPLCLEKHEIYELGDISFDMHPDRPLRFRQAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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            </authorList>
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    </dbReference>
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        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
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        <property type="project" value="TreeGrafter"/>
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            <end position="174"/>
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        <source>
            <dbReference type="EMBL" id="UJO19775.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCB8</accession>
    <name>A0A9Q8PCB8_PASFU</name>
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        <submittedName>
            <fullName evidence="5">Trans-enoyl reductase RAP2</fullName>
        </submittedName>
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        <name evidence="5" type="ORF">CLAFUR5_09846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
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    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
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    </reference>
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        <text evidence="2">Monomer.</text>
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    </dbReference>
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        <location>
            <begin position="10"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00008072"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="31381" checksum="12C35941DF38F436" modified="2023-09-13" version="1">MKSLQIPSLGSAPEIVDNIPVQEPASDQILVKSLWTAVNPIDSMIAAYGILVTDWPTGLGADAYGVVVKAGGEAKEKYGFQEGDYVVGCTRIGVREFATAQEYFLMDAAVAMRKPSNLEVPAAVTVGSAFQTAALGISKGLGISVGTTRNDVNEDRDWVLVLGGAGSVGSAAVQLLSQAGHAVVASCSPKQSSRVENLGAKGTFDYHLSLEEQIKAIEHITGDPGDVSMIFDATSSEDPILAKELFKTAELQGKEKLFVTTNDWSGIGGFEGGKTYEIHLGMMGRPEAREINEGIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCM4</accession>
    <name>A0A9Q8PCM4_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    </organism>
    <reference evidence="3" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCM4"/>
    <dbReference type="GeneID" id="71990484"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10606"/>
    <dbReference type="OMA" id="HEPMKNP"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040315543" evidence="2">
        <location>
            <begin position="17"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="26918" checksum="EDB4D5D301C22AA6" modified="2023-09-13" version="1">MRFALITAAIIGSVVALPTAQGNGNLDGNLIGNLNGNNGGSNNNFGKRQFPGAPAFGDGNGDGNLNDNLNNNNIGPGNSFGRRQLNGNGDGNLLNNGGMNNIGSGNNFGKRQLNGNGNGNLLNNLNGNNIGSGNTFSLRDAQGNGNLDGNLLNNLVGNNVGSGNSFGKRQGNGNLDGNLIGNLGGNNIGSGNKGNAPRDAQLNGNLDGNDLNDGRNNNVGSGNTFTPREAQGNGNFDGNGNDNGNKNNIGSGNSFKGPGAPAGFPSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCT7</accession>
    <name>A0A9Q8PCT7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10750</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764464.1">
        <property type="nucleotide sequence ID" value="XM_047909898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCT7"/>
    <dbReference type="GeneID" id="71990628"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10750"/>
    <dbReference type="OMA" id="KEMMVEH"/>
    <dbReference type="OrthoDB" id="17164at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000262">
        <property type="term" value="C:mitochondrial chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="278"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO20098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="327" mass="35767" checksum="DFDD3DDD577BD600" modified="2023-09-13" version="1">MNWTASRHAVAGLVALVEAPLCRHPVHRACRRAALQSRAVSTTARRWQQPAAAPTTPSPSRAAVNTAQVANELSPSDESEPRRSLTEGLDDPPPVLGEDEKQVDWTRSFHGLSAAPFAKEQSDILQQRLEFNDIEIKPDGIVYLPEIKYRRILNQAFGPGGWGLAPRGETIVTGNIVTREYGLVAGGRLISIARGEQQYFDPDGIPTATEGCKSNALMRCCKDLGIASELWDPRFIRKFMAEMGKEMMVEHVVTKKRRKHWMRKDDDLKYPLKEVTFPGQSSPVGNTQSGGVAPKAATAYKSATASPSATNTVNRVLPKKPVATASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD72</accession>
    <name>A0A9Q8PD72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764647.1">
        <property type="nucleotide sequence ID" value="XM_047909018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD72"/>
    <dbReference type="GeneID" id="71989748"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09870"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="28052" checksum="4F1065AF327AF983" modified="2023-09-13" version="1">MVKSAVEVEGAEVVKRLGDKQIEVDRLREELEMVKSQLPTKLDGSKKKKKLKLVSEEAFDDLKMQVGGLASEHKKLQQENASSKADIASARAREAVATQNHHSIQFQVNALSRTIGSISPPDTVVTRLSTLESDVQSLQSIPPADLQAGLLASKVTNLEADTREHKSQHSELRTKVTKVERKVHSLNAETTDWTETLVWVKNFNLWVMGQLDLIGDPRTIFPGVAWKEKAQKEKSEEICGCKLPGPLEKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDE5</accession>
    <name>A0A9Q8PDE5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pantothenate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10056</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764752.1">
        <property type="nucleotide sequence ID" value="XM_047909204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDE5"/>
    <dbReference type="GeneID" id="71989934"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10056"/>
    <dbReference type="OMA" id="WSKGAKQ"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24123">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000115">
        <property type="entry name" value="Pantothenate kinase PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.510:FF:000005">
        <property type="entry name" value="Probable pantothenate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="456" mass="50427" checksum="4E679F991CC9DBF6" modified="2023-09-13" version="1">MAEIVRPAMKKRRLSSSADMQQAIAQPGSIKINVTGAHIIDHEDGDSSPDRSPTSSQQEDEEHSFQHHKRDIRLPNHTAVVSHVAADIGGSLAKVVYFTRESTSQELGGRLSFLSFETDKIDACIEYLRTLQVKHQQTNGMDKATKLSIMATGGGAYKFYDRIKERLGVEVEREDEMECLIKGLDFFITQIPNEVFTYNDSDPDNAVEFQEPRSDVYPYLLVNIGSGVSMIKVSGPAQYQRIGGTSLGGGTLWGLLSLLTGARNFDDMLDMADKGDNSAVDLLVGDIYGEGMGYEKIGLSERTIASSFGKVLKRKREAERQAEDGTCSNGDTRTKFTPLTHDMDEAAGSGLVGDGRMFKPEDISRSLLYAISNNIGQIAYLQSEKHDLKRIYFGGSFIRGHQQTIHTLSFAIKFWSKATKQAFFLRHEGYLGAVGAFVKRKPPNWARAMSAEPGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE13</accession>
    <name>A0A9Q8PE13_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11609</name>
    </gene>
    <organism evidence="2 3">
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            <authorList>
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    </evidence>
    <sequence length="1600" mass="177085" checksum="EFC325F88E8A4B9C" modified="2023-09-13" version="1">MAEDTHPGHRASTTNANITVAIDPIALVVTECITVTSAMRKHARWAHSSISSILGSSPTTKSSPLARSSTPNDSPTPHDRRNRASSKIDLLPAQPTANDDEDAGLTSRWGLRGKKGQSMQDNPLMSAFAKLRSDLKHCRDIQEFETPSLLQPFLQVTRSSSTTAPITSLALIAITKMLAYNIVNPDSPGFGYGMQLLASTVTHCRFEGDNSPSDEVVFLRILKLMEDMICGSSGEVLGDQSVCEMMECALSICCHLRMSEVLRRSAEISMVTMCQTIFGRLKTLETEFEEGNEGEDIGKMEEDVGAEEMDKAKIESAPNGDFGPDAMKQSRNTSLEVPGMNGTPRPSEDVNGSQLGLSKGGEEDLVDVRPYGLHSIRELFRVLADLLDPHDRQRTDTLRVMALRIVNVALEVAGPSIANHPSLASLAKDTLCRNLFQLVRSENIAILHESLRVAGTLLATCRSVLKLQQELFLSYVVACLHPRVPIPDEPNIDPVLYEGVPAAPTLVRQQTASQAGGPAVPSSGRSTPVPVRDRQKLGMEGGSRKPDAREAMIESVGGLVRIPSFMVELFVNYDCEVDRSDLCMDMVGLLSRNAFPDSVTWSTTNVPPLCLDSLLGYVQFIADRMDDEPVTAGLPDQAALREQRRQKKVIIRGATKFNESPKGGIAFLAAQGIIDDPNDPYCVTKFLKGTTRIDKKVLGEFISKKSNEAILDAFIDLFDFQGLRVDEALRELLNSFRLPGESALIERIVTVFSEKYMKAAQPEQIVNPDSAFVLIYAIIMLNTDAYNPNIKAQNRMKFGDFARNLRGVNDNSNFDQDFLQEIYDAIKSREIVLPEEHDNKHAFEHAWKELLVKTQTAENLAICETNLYDADMFAATWRPIVATLNYVFVSATEDAVFQRVIAGYNQCAQIAAKYNISECLDHIILSLARISTLATETPPSTALNTEVQASGKSIMVSKFAVEFGRDNKAELATLVLFRIINGHEAAIRDGWTEIVRITVNLFVNSLVPTSFTSISRDLDLPPIMLQSPAQVIERNDKSADVGLFSAFTSYVSSVMNDEPPEPNDQEIEATLCTVDCINECHFEEILGNINELPVESLKSLTMSLLSHLPENESPRVISVKQDLPAPAPVRANGTKSTAELPVYNPAVVYILELVTILAMRDDDTIKALVPDVAEALQTVVKDADRVHPVALSRTVFYLLTLLKVSNDYDYIRAPVVLHYISSLRQDLLKETDKDILKGIYSCISGPPSLKKEIASSPDFWTVLHALQSKPESSQLVFQIAESVADGNTPAITSDNYEACVVLLNAFATSGSIGARFEQQHDQQARQQRAQKNKDDSTPEKKAQKKPEAVTRAIRAIAIVAKLASRVPTLISQSQLETDQAWRAYWSPVFRCLSTQCVNPCREIRQQALTSLQRCLLSPELASPDHTEWTNIFGEVLFPLIHQLLKPEVYQTDPIGMSETRVQAAQVLCKIFLHYLVLLSEWDGVLDLWLKILGIMDRLMNSGQSDMLVEAVPESLKNILLVMSSGGYMVPPPKEEEYDERTELQQQLWSETRERLGRFLPELMGEVFPDAPVGERRKEKESELPVRQREQIQAEAEAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEJ0</accession>
    <name>A0A9Q8PEJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765337.1">
        <property type="nucleotide sequence ID" value="XM_047910509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEJ0"/>
    <dbReference type="GeneID" id="71991239"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11361"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040298848" evidence="1">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="80" mass="8204" checksum="8A56DF2AF385651E" modified="2023-09-13" version="1">MKFLLLLSTLAALDTIGVIAGPVGHDTDIVPRAAGDLMVAPRAEAGGITIDLGDLGDLASNDDSDMVKSDGQYRGCECSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEP3</accession>
    <name>A0A9Q8PEP3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10807</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765403.1">
        <property type="nucleotide sequence ID" value="XM_047909955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEP3"/>
    <dbReference type="GeneID" id="71990685"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10807"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF11">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="31911" checksum="0281AFE99B99FAFC" modified="2023-09-13" version="1">MHEAMGHCKALAHPNWFATTIAALLVVGILGSYIPQFIKIWQKRSSAGLSPYWILLGGLSSICAFGNIISLPASREDISCCKEINGVACAAALLGVAQLVVQCTCFMIIVILFVVYFPTNNRDTAAATETEHPHEPPANEKHRLVVMLTIPSAIFTVLFVTIVITNAFHKYDQFWADLLGTIAGILAGIQYVPQIFYTWKLQDLKSLSVFTLLVQAPGAFVFAASLANRVGIKRGWSTWLPYVVTGTLQIALLIMAAWFKNTELRNHSASKPVGDDNSERAPLLPQRQPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ3</accession>
    <name>A0A9Q8PFQ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766130.1">
        <property type="nucleotide sequence ID" value="XM_047908256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ3"/>
    <dbReference type="GeneID" id="71988986"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09108"/>
    <dbReference type="OrthoDB" id="3853670at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="316" mass="36423" checksum="FF63B19A9DEC47DB" modified="2023-09-13" version="1">MVHILNTSCETHVRQHRRLHMLTFSRPSLHTPPQFCILLPLSTSHRVHRNFTRNSPPHLSTTKPVSHVNVFNMSEQTLQELQRLPSDLVADVPPTIAASNVGSPFFTKLPAELRVNIYELVLARDEDDPFETQSTILEEPSRISRDPPKKDSMPPLVYLSRQIRHEASPIFYGTSQFIATCDAGQPYPFPPSEVADWLYDIGKETAAEIKRLDVRFTAQTLGELEIWLWELSPLYGRENYWISGRMPEPTRERFWCVMRLGEYGLEERGVRVLYDGNEAGMRRECGGSWDEEFVQWTPHATSRREKCVNIIPSYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFV1</accession>
    <name>A0A9Q8PFV1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766030.1">
        <property type="nucleotide sequence ID" value="XM_047908741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFV1"/>
    <dbReference type="GeneID" id="71989471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09593"/>
    <dbReference type="OrthoDB" id="5396104at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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        </source>
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</entry>
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            </authorList>
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                <person name="Samaras A."/>
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            </authorList>
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    </evidence>
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</entry>
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            <begin position="35"/>
            <end position="86"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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            <dbReference type="EMBL" id="UJO21710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
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</entry>
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    <accession>A0A9Q8PGM7</accession>
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    <dbReference type="GeneID" id="71989094"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO22057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="80" mass="8970" checksum="46B449D90A2C57C6" modified="2023-09-13" version="1">MKKFQIATTVSTFKLNHRIIASAVYLSQFRNTETDLNDSGLNDIPSYYTGMAPTNYVITMITMSPNVVDKIKDGYRASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGQ0</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <end position="391"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="391" mass="41572" checksum="DE0B402FEFB703AA" modified="2023-09-13" version="1">MAMPVAGTWTLTLLAAVAQAQQQCYFGAGAENRGPENLVPCMATGASACCLRGDTCLSGNACFNYPSGNVYQYGCTDITYSDETCPFKCGFNTTRSPWTALEYCNDVQGAADNWICHGPESCGCEWPSSEGMLKLDPRGCRAMGSDAFVALYAPDQLAPYISLPLTASGSTGYYSPTVSDGSSTWVVTAVPGYTPSPITQLTTYRDPPTTRRRVAPGATPDASTYASAFTWTETRPGSLSATTAMPSQTTPRTTSPSLATDSPSSHTLSTSSKIGIGIGAAGGVCLIASLLLALFYMHRRHKKHAAQTSQSPEPQPHWPESPYMQQTAPHPNYPPYQPPMDRNWHPGPGVVYQAPAPEAETPASGKVSMSRGRDLPASELAGEERGMAHEM</sequence>
</entry>
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    <accession>A0A9Q8PGU5</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71988757"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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            <dbReference type="EMBL" id="UJO22260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="264" mass="30163" checksum="9CEB45E48010A8DB" modified="2023-09-13" version="1">MKLFEDNEKLVEKYATKKGIHFFLQQRVGKLLSQKHGRPQQEDHFQLSDITDWQFNLLPLLRLYDKKHTLTIHITEKWHNIATEVLSSSPPIRSKETFDEPSSPPAADPKRPSKKALTRANMAIVKKLSTKVEDYRDIVGLYKCSDRQCNNVKFSGQGHVGCLVEDGEHYAILGSHMNEWYALIDKYAGKPDAIALLKEGLPTTIAEKVRKMHKVATRFRSKKATPDTPSPSSTPVSVVQQQAVYQQPPYLYTYPPPPFYPPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH80</accession>
    <name>A0A9Q8PH80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase gloP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766738.1">
        <property type="nucleotide sequence ID" value="XM_047908604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH80"/>
    <dbReference type="GeneID" id="71989334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09456"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="49231" checksum="3125B7B6FCD7D28F" modified="2023-09-13" version="1">MTNIILSQDVSLTRILTGCFALLCTYTFTSLLITYFSSQARYLRLQQWTGIKHGQFATLRASLESFKHGRDMIIDGYHEFSQKGRAYVLPQLGSDDIMVLPPAQLQELMQRPDDELCVRVILQELIAAKWTGDMDVAAHNPLHLEVVRHQLTRKLPTLIEHVYTELVLGFQEQWKAAPHEWTDLVIWDSLVRIVSRAANRVFSGTELCREPEFLDSMRDYAQRIFASAAVINVIPRVLRPFTAPFLTWKLRGYIKTCKKYAVPIIERRLKEIQSGQQRESPNDALEWVIEECFKQNDPSELDTDKICRRLMRLNMVTIHNTSFTITNALLDLYSSPRSAEFVSALRDEVTEVLHKHDGKWTKAFINDLVKVDSAIKESMRVTAFNSVGVLRAVIKPGGITLNVLHHRASHTTERATFAKNCTTSTLITTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHT4</accession>
    <name>A0A9Q8PHT4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767038.1">
        <property type="nucleotide sequence ID" value="XM_047911029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHT4"/>
    <dbReference type="GeneID" id="71991759"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11881"/>
    <dbReference type="OrthoDB" id="5432at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="50872" checksum="B7E06DEB5889E274" modified="2023-09-13" version="1">MRSTAPTAWHTGAVTEVFECRNRRRVTQKGKQNRSVGTGARVRPTKDDLLGDVPRCQQRIKVISFTKHAEELKDTCKPGFGNCQCLPEWLYMKRTDKTVENNHVHTHDIDLLDRYKRSDALMYYSKLKIEEGYSYSAVLRYVHERYGPVTQQAYHLSKADVGNVSRPWRLQNKDVELKTEVEEESYEQKRRRECLDAIESTTQGALAKALAEVCRQIPQAVDIAAPFMEFPERDGDAESPGIVEGNDLVVSPPGIPTKKMILSEGFQGANTTPTSAQPVSAPSGPDGGVSQASQSAHALTSSTGATQSPPGPSTQTSAPHPMLPPPPPTRPPIPAAAISTDPETTSQAFISESSRTSQFAVPYQASRRVLPPPVRTSTSAQLWPPASITQPLARRTGNVVQPLSGSASSPGPRPSWAVSTVPQKRPIDAVRGDRDRPSPDKRTLVEEISAQLRDELRGSSSVSSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHT7</accession>
    <name>A0A9Q8PHT7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767270.1">
        <property type="nucleotide sequence ID" value="XM_047911140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHT7"/>
    <dbReference type="GeneID" id="71991870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11992"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF2">
        <property type="entry name" value="SET-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="24906" checksum="E36D812C775BC799" modified="2023-09-13" version="1">MLGLNNARNPKYSIDVSVGTNKRMRAAVDIRAGACILEERPLFKLDIALSRLYDIKSVTNEEVVPNGVKILQIEFARADYPTKQKIIGLYHGLDLTEIANLPLDEQAHTLLTAIIKLNAWSVIEQVDGQEHTILIMYNELSRINNSCTPNAMISWNAVTGRGSLHALQDITTNTEITIEYLAEPKDCFQKKTDRIAAIKEAYRFTAIVRCVLLRAIPTIIADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIL6</accession>
    <name>A0A9Q8PIL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Acyl-CoA dehydrogenase family member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_12060</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767467.1">
        <property type="nucleotide sequence ID" value="XM_047911208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIL6"/>
    <dbReference type="GeneID" id="71991938"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12060"/>
    <dbReference type="OMA" id="LAYMYAM"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="12">
        <location>
            <begin position="38"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="11">
        <location>
            <begin position="171"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="10">
        <location>
            <begin position="284"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="434"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO23101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="483" mass="53240" checksum="1E32A5D6E29E1679" modified="2023-09-13" version="1">MSNAPPLPTAGGKPRLPASQRLPSIAEPFVSARARKHLDTIEKWVDEECIPADAVYAAQLGHGDGRWEGHPSILDDTKQRARELGLWNMFLPKNHYSNLAEYDTYGGAGGFTNVEYGLMAELLGRSKLASEACNCAAPDTGNMEVIARYGTAEQKQQWLRPLLAGQIRSGFLMTEPDKASSDGSNISLSIRQEGNELVLNGSKWWSSGAGDDRCKIFIVMGLSDPNSQDRYKRQSMVLVPSDAKGLIVHRMLRVYGYDDAPHGHGHITFDNVRVPLSNLLLGFGRGNEIMQGRLGPGRIHHAMRSIGSAEYALEWMIARLNDERKVPFGKPLREHGVLLEWVAKSRIEIDAARLVVLNAAIKIDNGDAKSALVEIAEAKVLVPQTACTVIDRAVQAHGAMGVCQDTPLASMWAHIRTIRIADGPDEVHLNQMGRRETRARAQECINRIQDQKERAEALMKKYGVDDKQLGGSKVQGFQTRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJA8</accession>
    <name>A0A9Q8PJA8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calpain-like protease palB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12713</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family. PalB/RIM13 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767874.1">
        <property type="nucleotide sequence ID" value="XM_047911861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJA8"/>
    <dbReference type="GeneID" id="71992591"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12713"/>
    <dbReference type="OMA" id="GDYRRGC"/>
    <dbReference type="OrthoDB" id="167576at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25435">
        <property type="entry name" value="PalB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="171"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="912" mass="102465" checksum="EADA23B93F9AD57A" modified="2023-09-13" version="1">MSAPSRDLEELRQDAERLATQPPQCSSRDEALEVAIKAAETAFSALRLVKDPIEKAKYTARAKALMQEAEAIKQSKDWREAIAPTSQPRGEAAFDPSQIRLLKEPVNSRALPTSEQIIILRAGFLNGEKFPEWSGAPSPSEFEHKDGEELFLDDSSELPLSDFQLDVLDDWKRPIEALPPPSWFPGDRTNLGPSMNFFRDIDLVQDAATDCSVVASLCAGVARGKRGHPRMMQAFLYPYDVNSGKPYLSKNGKYVVRMNFNGCFRKVVIDDRLPTSSTERVIHVVDRNNPGLLWPALLEKAYLKVRGGYDFPGSNSGTDLWILTGWIPEQVFLQADDLEPDRFWKRMLNGFFYGDTLITLGTGKMSSKTERALGLAGEHDYAVLDLKEIDGQRLMLIKNPWIEGTSWRGRFKNTTRGKSNTQVQPGDSPLIQLEDDPEPVDSPRDLLNVDDQLTPGTFWMDLDNVLQHFESIYLNWNTGLFSHRQDIHFAWDLSEPADGGVGKTRGPYASLQHNPQFTVTASKKGDIWILLWRHFHNSVPDTATADEIESGRHFIDLNGHISLIAFASGGKRVMLPERHLQKGWFVDSPQTLLKLEGCEPNKVYTIVPLEQELPATKHSFTISAFSDSSVAVSQATPRYAYAIEALGMWTKDSAGGNAQTMTYCDNPQYSLLVAQKTSVSLLLEACNPQLNVHVKLLHSNGKRVFCIRNKDIIVDSRDYRPGCCLAETEELDAGQYTIICSTFEPQQLGNFSLRIESNQPTQARLLPREGAGRIRTELSTVAFKNGENKVAAPLHPKRLVNFYAIARYMDNTRFRMSNHSHVRLSIECGRGPTRRMVIASNGGDFSDSAGSIRTEPIDLSYNEIRRFGHGDCWIVLDRMSVSSDNQEERFRIEIFADQPDAIDCGVWRAWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJN6</accession>
    <name>A0A9Q8PJN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase sdcF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768008.1">
        <property type="nucleotide sequence ID" value="XM_047912039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJN6"/>
    <dbReference type="GeneID" id="71992769"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12891"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040387870" evidence="5">
        <location>
            <begin position="20"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="61"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="501" mass="55251" checksum="588A17E411203583" modified="2023-09-13" version="1">MRDLTAIAAVLFLLPGSFALQKHLQGNDCCNVLREAGVGNIFLPQSKNYTERVHSYWSLTSQLEPNCFVLPGNAEEVSTIVKTLVEKTKCEFAVRSGGHSSNAGYNNILNGVTIDLSRINSTTYNNATQIASVGPGARWLGVYRTMDALDRGIQGGAIGTVGVGGLLLGGGFANYAYQRGLATDDIVNFEVVLANGSIVQANATHNQDLWRTLKGGGSGFGIVTRYDMYTFERPLMWSSYREFSASEELDEAHIRGLKHWTDNEEAYKSGAAYVWWTYRPADNDTILIAMVGDTSGQANPPAAQEFLNISGAKTESGGLTNMSQEALATQAEGYRNIWWTLTLKNEEHAIRKAVHLHHQLVSEMLRDSVNLDFETQAYFQPLPIIMAQRAAEKGGNTLGLDRIGNNSVILLASLAVNGVDQEALGRQKMYAWLRALEQYTEATGTMVEYKYMNYADATQDVLKSYGRENVKRMQRVSSKYDPEGVFQTRAPGGFKLPWGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKC1</accession>
    <name>A0A9Q8PKC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768409.1">
        <property type="nucleotide sequence ID" value="XM_047912194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKC1"/>
    <dbReference type="GeneID" id="71992924"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13046"/>
    <dbReference type="OrthoDB" id="2015405at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050268">
        <property type="entry name" value="NADH-dep_flavin_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466">
        <property type="entry name" value="FLAVIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466:SF1">
        <property type="entry name" value="FMN REDUCTASE (NADH) RUTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="4">
        <location>
            <begin position="435"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="646"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="335"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="714"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="739"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="790"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1062" mass="118172" checksum="4D1A6D14CF8030F6" modified="2023-09-13" version="1">MQRPSLAARRFYADFYRWVTSTSRPTEHTLHPRLSCKKAFHTTTWHHARKEPLRLRIKRYESSRDPRDTWKADSTTAEPKHDDVFKALADAVPQSPLAKPFSALKEQEFVLRYRSAGSLMVEAAIPEEDLHQVQSFRRTQGARIEAQYDVVSTVDGQKLVSVLLSGTREEVRSAWSVLCSRRNSVPIPDDVTTFLVRPSETLLPLESVLRIKAANGNRKLELSVLEYQWMRFVAAHDLERIARDTKAQIEVTQPSMRPLDPASALTRLARSFLISGQAASVSKAYGQIYATIKFAIPANDNKKTKSEPEAEVEKAPSVEEPVVTRWFEFSGLSRHERHRNFLHELESNLEELRRKAGCQSLQVTGGQGSLKAQGTPSQLNILQKTLVDRVARICEKVGATVPGTRMLKNRPAHRAPKPADQDNDERLVEGTRTALRALTHPVVVVTSRMPGRGDKFERMRTARAVTVSSFNTVTLHPRPIISFNLKKPSSTWDAICESKWLRVHLIAGTPRGAAIASVFTQPYKQAHDGTRRLFHMKVLTKVREGASPPNMYSPYGDVLATLNANLREHHCVDVGDHVIVVAEVEHLETVLKPDGTPWMTDISALSYSNGSYSSGSAVIEPQKLPEMGPEEDLAKEFFDTRASIKADSDQASPDPLALGRAPDSPVDVYRPVAKSADTEVAPAPERAKDRPEEMVNDPIYSALLAAKDSDVKFSPSQQDSKKSPSSRSAVSPSRHDSNKSPSSRSAVSPSRQDSKKSPSSRSAVSPSRQDSKKSPSSRSAVSPSRHDSNKSPSSRSADNSGALWGPKDVTREESERLAENAAPRASPSRAPRIERGRQGSKNGGPERPYSTFARSRACVYPSRRTFSSMQAVRSAPEHTSVHVDPAARNMTVADFFGVPDEGPAHRPQVDGLIRADKTAHLAERRLAKNPDLPEEEKLRLQHHIQVTNRKMSKKLAWNAAIDLRVMLDKGKVNLQRAQFLESAIEKGQMTLLEDARRVRELLNQGKIDLEKFNAIKKSLEETSEVLTTEAMRLRQVVDEEGDYFENAANDEEAGFDGFKGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKJ0</accession>
    <name>A0A9Q8PKJ0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Monothiol glutaredoxin-5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13818</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768514.1">
        <property type="nucleotide sequence ID" value="XM_047912966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKJ0"/>
    <dbReference type="GeneID" id="71993696"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13818"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="52"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO24148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="16794" checksum="8BC05D4E0A4B2BAD" modified="2023-09-13" version="1">MFSRTAFSAVAGAALRPCRNPLLSSRFAALQKSLLSTETRQAIDKAVASAPVVLFMKGTPETPQCGFSRASIQILGLQGVDPQKFTAFNVLEDQELRQGIKEYSEWPTIPQLYVGNEFVGGTDIMMSMHQDGSLAKLLEEKDVLIPAESEGSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKK3</accession>
    <name>A0A9Q8PKK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKK3"/>
    <dbReference type="GeneID" id="71993035"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13157"/>
    <dbReference type="OrthoDB" id="10582487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040497170" evidence="1">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="14056" checksum="A7D0B97E35EDED7C" modified="2023-09-13" version="1">MARITAILALASGILLPVTKAWVVALINDNNCNTAAAYYSYHGEGMGNCIKVGDNVDNCLYVANGGNEGCGSQNLITKSNMGMTMADGTQCFMGQDNRCSMNQMFSFGCSLPAAVQPATALESEFYVQCWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKV4</accession>
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        <submittedName>
            <fullName evidence="2">Derivative of benzaldehyde biosynthesis cluster protein C</fullName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768656.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKV4"/>
    <dbReference type="GeneID" id="71993244"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13366"/>
    <dbReference type="OrthoDB" id="5519740at2759"/>
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    </dbReference>
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        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
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        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
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    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="41"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="142" mass="15893" checksum="DD6E5AE53C19951F" modified="2023-09-13" version="1">MLTPRRLFTSLKAHSSLLPCRSPATLRTLTNTASIMGKQEWIVILPDYPGALEKRMEVRPQHLEAIKPRVQAGTVVLGGASLDEPAKEGSPMKINGSVMMAEADTEQEVREIIESDIYYRTGVWDKEKIRIFPFKSAVRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL36</accession>
    <name>A0A9Q8PL36_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_14006</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768867.1">
        <property type="nucleotide sequence ID" value="XM_047913154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL36"/>
    <dbReference type="GeneID" id="71993884"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14006"/>
    <dbReference type="OMA" id="GCGDCTN"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040272547" description="Pectate lyase" evidence="11">
        <location>
            <begin position="16"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="24859" checksum="A890BDD098EC2BA4" modified="2023-09-13" version="1">MKTTFALTFAGLAAAQTLNIPSRSGSIVSLSSPMTISGSRDFGNAEYDRGRECDTDEDTGSESAVFILENGATLSNVIIGPNQLEGVHCKGACTLRNVWFRNVCEDAISALGTGNVLIEGGGANGAHDKIVQHNGRGTVTIRGGTYTNSGKLYRSCGDCTGNGGPRNVVVENVRINGMSSDLVGINSNYGDVATISGSCGVSKKVCQEYVGVTKGNGKSEKTSTTASCKGAQGTLSKLPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLY7</accession>
    <name>A0A9Q8PLY7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769226.1">
        <property type="nucleotide sequence ID" value="XM_047913728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLY7"/>
    <dbReference type="GeneID" id="71994458"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14580"/>
    <dbReference type="OMA" id="CICTTAD"/>
    <dbReference type="OrthoDB" id="4843554at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040421525" evidence="3">
        <location>
            <begin position="21"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="19764" checksum="99A6D0D42C1C3FA5" modified="2023-09-13" version="1">MQYTTILTTALIATANVACADWLDQEDVPSQCNDVCRPVVQASDRCEDQFDDDDDQRNCICTTADFNTIIPNCELCIRNSSDDEDEIRDLRQDCGLPNPTGSATGSAQSTPSVTTSTSMATVTQDGTTTTSQSVVIVTLTTGNAQTSPTSGSSDSDDDNNNNNQNGAGSTVASLAAAGAMAIGAVLMAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM54</accession>
    <name>A0A9Q8PM54_PASFU</name>
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        <submittedName>
            <fullName evidence="6">Fluconazole resistance protein 3</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">CLAFUR5_14329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769374.1">
        <property type="nucleotide sequence ID" value="XM_047913477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM54"/>
    <dbReference type="GeneID" id="71994207"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14329"/>
    <dbReference type="OrthoDB" id="4940293at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF8">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="114"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO25008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="33251" checksum="09545DC60764581B" modified="2023-09-13" version="1">MEAMDYNYFASAQQPYQYMGYGDAGLLSSTGEVIGATPSMEGLNSGSFSLSNFDYQFDTSLGQGLTPLPTASVSPPPQHLSIRPNGSVDSGIAVDMEHEGHGRRGSSEEKDSLTPAQSRRKAQNRAAQRAFRERKERHVRDLEAKLNLLTTTTSSLQSDNERLKLMLQRAQTENEILRATASSSPTSHHPPSFVDDPSLLPSHRPSKGSPKPHLDAARLANGLLSSDSTSPRYGSSPGSDSNLLSASATWDLLQSHPLYLSGAVDIGEVCERLKKMARCDGMGPMFGEDEVRQVIEEVGRSGSDELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM60</accession>
    <name>A0A9Q8PM60_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769339.1">
        <property type="nucleotide sequence ID" value="XM_047913217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM60"/>
    <dbReference type="GeneID" id="71993947"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14069"/>
    <dbReference type="OMA" id="ICGPWDA"/>
    <dbReference type="OrthoDB" id="3928002at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38049">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38049:SF2">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040238983" evidence="2">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="27664" checksum="EB1D990709C67520" modified="2023-09-13" version="1">MVLGLLTAIVACPAIVGTTEAVRHGQRENNREEHRGRRHNLVVTLLNRSEYSQRFDGAYIFLKNNKLWIDTSGVSRREGLHPVTSYFLAYPNMEAVWQEQGFRRGEGMVTTISVEPPFLNWVYVDNKTHEVKYGVRTDTVGQLVGPWDVTKTDRRLSFQGWEGFVAVEENEGDSMWALYFDVEDDGLRDNGRVGDQGKRMLALEIWRREPRVGYDAAVEERQDRIQARAEHDGESSVSTTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM61</accession>
    <name>A0A9Q8PM61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7791 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769535.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM61"/>
    <dbReference type="GeneID" id="71994145"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14267"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7791" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="31838" checksum="F6600C23BB4DF98A" modified="2023-09-13" version="1">MAARLETFLSSSTKDLLVLRRPLDNSLPVDVDFLHRSVYDFLCTNRMQQVLLGNTPKAFHTGRIIHLMDQAKMILAAGVVDYGENNVRAVAQASLGQPHLDLNSYYAASFEPALMAHVRQDIHAPDNTRYVGKARDAPDDNNRNMDACIASLIAGGAFTFATKYYHLNHPDHVWALTPSTCFAAALGLHPTMPYGLQHVNVDFLRRFRAGFLGTWDVEGYRNPIEHDMENMYRHCGNNVMQHFFNKWATEAHRQEQDYDSKVLPVVWEIVKTFSGPTESMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMN5</accession>
    <name>A0A9Q8PMN5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769644.1">
        <property type="nucleotide sequence ID" value="XM_047913510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMN5"/>
    <dbReference type="GeneID" id="71994240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14362"/>
    <dbReference type="OrthoDB" id="3640545at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="23500" checksum="DB94FBA58D7314EC" modified="2023-09-13" version="1">MVTIHCGPEKKVFLAHKDTICATSEYFKAACTKQWVEGQTGVIELADGKPDTFQTYLHWTYTKEFDLTNMFANTRKRCCYGWRDMTALWTLADYLGNRELRNACIDIIYAQMKAQPARGIRASTVVEIFEYTPSGSGVQRLIADHVAFSAGKDKSIEPIEQQIAGLPTYVVGIMAKKYYDALTDKSALWPAGRCSYHDHEEGESKCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQH2</accession>
    <name>A0A9Q8UQH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell membrane</location>
            <topology evidence="1 6">Lipid-anchor</topology>
            <topology evidence="1 6">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763081.1">
        <property type="nucleotide sequence ID" value="XM_047906068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQH2"/>
    <dbReference type="GeneID" id="71986798"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06920"/>
    <dbReference type="OrthoDB" id="3649192at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF2">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="48716" checksum="78142BCF476CA6CA" modified="2023-09-13" version="1">MSELQYYLRPRPAYEPVRTEGDVFWRDGDRFLIKGINYFIRHPKPPGEPLYPIHKVDCLSEEHLETLQRDVKVFRELGLNTIFIPSLDPTKNHHEALKLLAQAGIYVLVTIGEGIARPPQPDAGWPSFDTDFDTRTYHTTESLERSIRIVDELASYPNVLGFIVDGSALVDLKATKIAEVHRAHVRDIKSFLHLRGGRQIPVGVALCEILNFQLQAVQYFSAGPSTDLSCADFIARENWSWACKSDFRISGWKNMVKILQEYPIPMFLGEYGTFVGYRLWEEVPCLYSRDMTGVFSGGCLYTYCDDGSKYGIVEEDEGGGITRKPEFELLRKHFRTVNCRMPEELYDSHVKDYESWTGEFPERDEHCWFATRDLPECPVDLERFMLELRQEKEWEVISHRTEGLKLWNRDCTVYNALYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URM8</accession>
    <name>A0A9Q8URM8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aurofusarin cluster transcription factor aurR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764279.1">
        <property type="nucleotide sequence ID" value="XM_047909578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URM8"/>
    <dbReference type="GeneID" id="71990308"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10430"/>
    <dbReference type="OrthoDB" id="2269373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="608"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="707" mass="78053" checksum="E2E181EC1363FD53" modified="2023-09-13" version="1">MEAQPQKRDNHTPSCAVCQRRKVKCDRVYPCAACTKSGLECAFPPPRNGKRARRSTTHQHGPQMQEPAARPPYSSAPHVDRATAGYSGGMRHGSNELPSPESTISTGTNNARLVSDGAGYRYVNNHLWSALSTDGHADGRSPGASTEDHKSSGAGSRSGHAIYEDIARGGDEGSEGRSFLFGNASSDSRSVAEQPVPPANHVVFLWQTFLANVDPVMKISHAPTIQPILLGQIGRPNIPANEKVLVSAIYFISTVSLTDEQCVGSLQDTRANLLKRNRIATEAALSAAGFITTTDTMVLQALILYLAALRSLGEVQTVWSLFGLAIRIAGTIGLARDGTSFNLSPFETEMRRRLWWGIVYFDGRMAELVGQDGDLMGNDYEAAQPSNLNDNDLFPTMSRFPEPRKGPSDAIYLQARILSVTVARRLQGLAGPQGTWHKLREATMSTREKLDIMHHIEQRYNAEILEICDPSVPLQYLSINTARTFATKLRLIARIPIVDLDRDWEDPTGFSENAFLLSMDLLQLQVDLWCEPMVAQWRWHWQAHFQWYALVSLLRQTRLRQTGHGISRAWMLIQKAFEIIIPTLELGERKSLLLSGIHNLLDAAKRQQDQADSAAHDRKPPAQRNTPVMVQQPGPAMPPNGFSAGYGARPHTAVLPSMEQVRSQAQTPVSFGVSATALEQADPIFGLDLDAIDWVEFDRLATELCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URV7</accession>
    <name>A0A9Q8URV7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764493.1">
        <property type="nucleotide sequence ID" value="XM_047909837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URV7"/>
    <dbReference type="GeneID" id="71990567"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10689"/>
    <dbReference type="OMA" id="VNSITIW"/>
    <dbReference type="OrthoDB" id="5337308at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="337" mass="37369" checksum="157FD3C9FAC842B2" modified="2023-09-13" version="1">MPVTLAMNNTACSKALGLAALVAIAIVFGLSTMNANPHDNTNIARNIHNERHSNITIYEPPYNTHNAPHSNLTARDTIWEDKVYKGHWLACLMNAQPEHVEQSHFTTNADLTQNGWQTTERPAANQRTFNLRGYVGALKGLGLDTNFEHWITVQGRHAGTGGQYTNAYNPWGGILIAESNHGPDFVIGERTKKGIAVGPAPALKNWSDVVFLVWAMLCRRSNIDQNPQGLEHVFRSMVVNEATTETLRQARGNGNSDGVDDFPPKWPGWSWNIDTDPGRAAISTRNGVGVAYFLFQHKEALGIKVVDRIHAFNCPDYTEAPKFCMYMHLVDGPIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT42</accession>
    <name>A0A9Q8UT42_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765870.1">
        <property type="nucleotide sequence ID" value="XM_047908410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT42"/>
    <dbReference type="GeneID" id="71989140"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09262"/>
    <dbReference type="OrthoDB" id="426133at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01831">
        <property type="entry name" value="Endoglucanase_E_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037461">
        <property type="entry name" value="CtCE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052762">
        <property type="entry name" value="PCW_deacetylase/CE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834:SF2">
        <property type="entry name" value="ESTERASE, SGNH HYDROLASE-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37834">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G00620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040149183" description="SGNH hydrolase-type esterase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="177"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="47187" checksum="0C2CAB33199A50F3" modified="2023-09-13" version="1">MKTSLLPLVCLGGLASATIWQNDQVRPSNYPSTEISLQSYGNGTQWRDYAPDCAELSYKGRWDEQYISWWSAPGLKFGFQADNVAISFGNYTSPGVLLAYRLDGQDWTLTNVTAKSTHLFIDPSTPGWNLTTSIDNLRTLELRVTNWAFGVQIEKVHLSGGNASLVKIPDYARRIEVIGDSLSSGYGDTLEGISSWAWGLAYGLGNTEFSLTAYPGVCVTDTDCWGNPRGQSHQWKKTVDTSGRAVEMYGPNLTDAPDWDFSKQEHPDLTIINIGTNDNNTHNNVTSESFTAAYISLIEQVHEVWPETQIIVQSLWSGWGQVGSTWVQGAGFYEEIQTIVKHFNNGKLNKKGGEGFVYYYNTTGIMQHNDNSPLFHPTDVGQIKVASHMMEYVRLIFDWELMQTGPEVQHQTLYWNDMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTB1</accession>
    <name>A0A9Q8UTB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Complex I intermediate-associated protein 84, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766110.1">
        <property type="nucleotide sequence ID" value="XM_047908397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTB1"/>
    <dbReference type="GeneID" id="71989127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09249"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF5">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="676"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="841" mass="95583" checksum="B3F732298FF89D66" modified="2023-09-13" version="1">MPSHLTRHIFRRILANEPILHGECIRQRACSTASPSLRLSRRQNAAHGPAQQQRTFLNFNMFGKKKRDVKEADLDPGIEVMMHYTKMERMRARLPPVEEVAEALRAFFKSKTDRNQPIEDTQAQLAVQSFRYYLNGRSTDDDPDSLSGRGLVNQKLMKDATRALRRTLKATPSHVALGKELYHAYAHALPLSNHHMARKTLGAYVHVLSQAGNVQSALDVLVQYENRIASRNTSNQENEYDEDEEEAVHTRGATPTSTTSTDLAIARAWRTLLRGVADVGDEDQLIRTLDMLRSRGYAEHSGIPFSMLQFYVRTDDTEAVKYWFEQCWQAKNRPTTAGDISYLAYTLRCTLGYYLDRQKLEYGHQIVRQVMAENPPKPVWDAIFVWAAGTGKGADEIGRMFTVMESSNEGIVEQDQWRLPDITTINGLVEFATSRNDPYLAERFIALGKERGIQPDATTYVLQMKYRLKVNDVDGALIAYKNLQSMDLSTNEDVPAVNQLVVALCSSKRHDFDTIMNVVADLADRRARFEPLTVSTLSLLHLSRDEVHDVIDLLNTHSYRFSSTEREAIRTKIVDYCLDKATPVSRSWDGYTILRSIFDEMPRTQRTELMVSFFERQRPDMAANVFQGMRTHSRPDTIPTVDTYVAAFLGSAKLRDLESLEIIHNQLKLDFNIDTTTYLYNALIIGYTACGKPRRALDFWEDIVASKEGPTYNSIHIALRACEKAPFGDLKAQEMWAKLKRQNVELDQSLWASYVAALAGNGDNELAITTIEKADQNNEVEVDAFLLGSLFGGSSGQDPQAEIESWAKEKYPHVWAELEKVPMDTREDGMRYFRIDRSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTC5</accession>
    <name>A0A9Q8UTC5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">glutaryl-CoA dehydrogenase (ETF)</fullName>
            <ecNumber evidence="11">1.3.8.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_09802</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13389"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid metabolism; lysine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid metabolism; tryptophan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="11"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766097.1">
        <property type="nucleotide sequence ID" value="XM_047908950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTC5"/>
    <dbReference type="GeneID" id="71989680"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09802"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01151">
        <property type="entry name" value="GCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000003">
        <property type="entry name" value="glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000006">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000008">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="44"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="162"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="273"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO21731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="46709" checksum="253E99B214FB1819" modified="2023-09-13" version="1">MFRSVTSRAARQLTKPSYTAVRNASGTANKFDWQDPLGASNLFTEEELAISETAEQYCQERMLPRVLDTTEAFRNEEYDRQILTEMGELGLLGATIKGYGCAGVSSVASGLITRAVERVDSGYRSGMSVQSSLAMGGIEEFGTEEQKEKFLPGMAQGKILGCFGLTEPNHGSDPGSMESVAKPHLTKEGYYSLSGSKTWITNSPIADVMLVWAKLQETGKIRGFLVERKNAPPGTIETPVLKNKNGLRASITGMIQLDDYPVPKEMMFPDVEGLRGPFSCLNSARYGIAWGVMGALEDAIARAREYALERKQFKNNPIAKYQLVQKKLADATTDAAYGILAAYQVGRLKDEGKAAPEMISMIKRQNCDRALIGARNLQEIFGGNAASDEYHIGRHVSNLFVTQTYEGQSDIHSLILGRAITGIQAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTU8</accession>
    <name>A0A9Q8UTU8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Altered inheritance of mitochondria protein 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Found in mitochondrial proteome protein 29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIM9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766665.1">
        <property type="nucleotide sequence ID" value="XM_047907963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTU8"/>
    <dbReference type="GeneID" id="71988693"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08815"/>
    <dbReference type="OrthoDB" id="2968323at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051035">
        <property type="entry name" value="Mito_inheritance_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="7">
        <location>
            <begin position="93"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="38444" checksum="08FA6E30630F1509" modified="2023-09-13" version="1">MMSRPFDMIGSLYFGDTGVPGCKPIMVDRNVDSAHRFSIGPITRREFWQDERASMGHQGPWTSSTDYLQSIADREIEWLSKSAHRHPQSRQPWQHAGPLQDSADAHIASLNKFKAVITDIVPRDEDLTRPRFWHPDSHAGNIYVDEEANITAIIDWQGAWITPPFIGINPSPILDYVDIMMKLPENFKSLHEADKEKLRYRMSQSILITAYETETASINPPLIEMMRTAHSQTLKQLEAFANATWDNALYPFNETLLRVQQEWSHFGLDGNCPYEFSASEMQQHQDEAENFDDSQRFWHNVRGVLSEDGYTTNDDYPSAAKVLKELQNTAERSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV53</accession>
    <name>A0A9Q8UV53_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosylmethionine-dependent methyltransferase CRG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767868.1">
        <property type="nucleotide sequence ID" value="XM_047912344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV53"/>
    <dbReference type="GeneID" id="71993074"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13196"/>
    <dbReference type="OrthoDB" id="3649598at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF10">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="33931" checksum="8B18F66A6CD8E423" modified="2023-09-13" version="1">MPQEKIFTSFTPEQAASYAKNRGLNYPQQLYDTILDFHQGSRNVVLDVGTGPGTVVFNLLPHFAKCLGCDSGEGMIAQARQTAERLQLGERVAFSLCGAEECEKAFPEEKADVITVAIAAHWFNLEPSYAAAARALVTGGTLAMWTCSHMWVHPSTPNHAEIQAVLSDVENMLVPYMTAGTLLTQNLYRDLKLPWDFPESKESFDQASFERRYWDLNGIPSSAPLPDGTPGPFALISDPKALHCSVSMFVKALGSTSSVIRYRQANPDKANTEDDFMHVAANRLREANGGKDALWMSPSMSLLLLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVB4</accession>
    <name>A0A9Q8UVB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768063.1">
        <property type="nucleotide sequence ID" value="XM_047912080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVB4"/>
    <dbReference type="GeneID" id="71992810"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12932"/>
    <dbReference type="OrthoDB" id="10656293at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10407" checksum="AA9FADB5FBA49C95" modified="2023-09-13" version="1">MSDPNAPGAKVGTKDIPVEIQQLASTIKALPKTKDGLPVRKELKGIDAQYFTAGGTILRRNKGTDLLDWFLDGRLFTNEKFTAATRQAPQAVEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWU4</accession>
    <name>A0A9Q8UWU4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769623.1">
        <property type="nucleotide sequence ID" value="XM_047913220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWU4"/>
    <dbReference type="GeneID" id="71993950"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14072"/>
    <dbReference type="OMA" id="WWEYDSS"/>
    <dbReference type="OrthoDB" id="2884623at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="202" mass="23125" checksum="B1071922E1FFBC82" modified="2023-09-13" version="1">MSTGTIFITASNADFKVANRFLLLIRDWEYGSGDRFHIKIDKNHVRFDANGYNNTVTDAGSLTADNFTNEWKGASLSDVETWMLEATRQDPTGDPSLWILLDDEGVEQQTCILAERRMPEDNYGMDPKPTFTLNKIRLSWEEVYSPWCNLDIANMSFDEFTADGPDAEGWWEYDSSSSSDLPDEKKQERDNEVQRLKEEGKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-06-18" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>Q00367</accession>
    <name>HCF1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Class I hydrophobin 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hcf-1</name>
        <name type="ORF">CLAFUR5_04324</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1997" name="Gene" volume="193" first="89" last="96">
            <title>HCF-1, a hydrophobin from the tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Spanu P."/>
            </authorList>
            <dbReference type="PubMed" id="9249071"/>
            <dbReference type="DOI" id="10.1016/S0378-1119(97)00090-5"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>DEVELOPMENTAL STAGE</scope>
        <scope>SUBCELLULAR LOCATION</scope>
        <source>
            <strain>Cf4</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1999" name="Mol. Gen. Genet." volume="261" first="644" last="652">
            <title>Isolation and characterisation of five different hydrophobin-encoding cDNAs from the fungal tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Segers G.C."/>
                <person name="Hamada W."/>
                <person name="Oliver R.P."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="10394901"/>
            <dbReference type="DOI" id="10.1007/s004380050007"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <source>
            <strain>Race 4</strain>
        </source>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2001" name="Fungal Genet. Biol." volume="32" first="159" last="168">
            <title>The hydrophobin HCf-1 of Cladosporium fulvum is required for efficient water-mediated dispersal of conidia.</title>
            <authorList>
                <person name="Whiteford J.R."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="11343402"/>
            <dbReference type="DOI" id="10.1006/fgbi.2001.1263"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2004" name="Fungal Genet. Biol." volume="41" first="624" last="634">
            <title>Stage-specific cellular localisation of two hydrophobins during plant infection by the pathogenic fungus Cladosporium fulvum.</title>
            <authorList>
                <person name="Whiteford J.R."/>
                <person name="Lacroix H."/>
                <person name="Talbot N.J."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="15121084"/>
            <dbReference type="DOI" id="10.1016/j.fgb.2004.02.005"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>SUBCELLULAR LOCATION</scope>
        <scope>TISSUE SPECIFICITY</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6 10">Aerial growth, conidiation, and dispersal of filamentous fungi in the environment rely upon a capability of their secreting small amphipathic proteins called hydrophobins (HPBs) with low sequence identity. Class I can self-assemble into an outermost layer of rodlet bundles on aerial cell surfaces, conferring cellular hydrophobicity that supports fungal growth, development and dispersal; whereas Class II form highly ordered films at water-air interfaces through intermolecular interactions but contribute nothing to the rodlet structure (Probable). Hcf-1 is a class I hydrophobin that is not necessary for the development of hyphae or conidia but acts as the main determinant of conidium hydrophobicity and, thus, is required for efficient water-mediated dispersal of conidia (PubMed:11343402, PubMed:15121084). Forms a component of the rodlet layer, but other hydrophobins must also participate in this proces (PubMed:15121084).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-assembles to form functional amyloid fibrils called rodlets. Self-assembly into fibrillar rodlets occurs spontaneously at hydrophobic:hydrophilic interfaces and the rodlets further associate laterally to form amphipathic monolayers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Secreted</location>
            <location evidence="6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="tissue specificity">
        <text evidence="6">Abundant on conidia and aerial structures formed in vitro and emerging from disease lesions on infected tomato plants.</text>
    </comment>
    <comment type="developmental stage">
        <text evidence="7">Expressed in growing mycelium and conidia but its quantity diminishes transiently after germination.</text>
    </comment>
    <comment type="induction">
        <text evidence="4">Expression is increased during sporulation (PubMed:10394901). Expression up-regulated by carbon or nitrogen starvation (PubMed:10394901).</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="4 5 6">Leads to the repression of hcf-4 and induction of hcf-2 and hcf-3 (PubMed:10394901). Decreases the hydrophobicity of the cell surface (PubMed:11343402, PubMed:15121084). Leads to very few rodlets, which are found in dispersed patches (PubMed:15121084). Does not affect the ability of the fungus to grow in vitro on agar plates or in liquid culture (PubMed:11343402). Does neither affect mycelium growth and sporulation, nor the frequency and speed of conidium germination (PubMed:11343402).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="X98578">
        <property type="protein sequence ID" value="CAA67187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q00367"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04324"/>
    <dbReference type="OrthoDB" id="3648449at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0134">Cell wall</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040716704" description="Class I hydrophobin 1">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q04571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="10394901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="11343402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="15121084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="9249071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="10394901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="9">
        <source>
            <dbReference type="PubMed" id="9249071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="10"/>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CAA67187.1"/>
        </source>
    </evidence>
    <sequence length="105" mass="10455" checksum="4770BB96F65E004B" modified="1996-11-01" version="1" precursor="true">MQFTSFAILAISAVASARVTRRDDSSATGADKGGTCAVGSQISCCTTNSSGSDILGNVLGGSCLLDNVSLISSLNSNCPAGNTFCCPSNQDGTLNINVSCIPVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXU5</accession>
    <name>A0A1P8YXU5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10651</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">0WU</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4 7"/>
    <dbReference type="EMBL" id="KX943169">
        <property type="protein sequence ID" value="AQA29340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764006.1">
        <property type="nucleotide sequence ID" value="XM_047909799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXU5"/>
    <dbReference type="GeneID" id="71990529"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10651"/>
    <dbReference type="OMA" id="QDIWAPS"/>
    <dbReference type="OrthoDB" id="195678at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18831">
        <property type="entry name" value="GH43_AnAbnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573484" description="Arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="9">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR026534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQA29340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="340" mass="37119" checksum="273C5307D885EA88" modified="2017-04-12" version="1">MTFTLLHAFLLPALIRASPLLKRDYPPVGACSGKCQGRLHDPAVIYREDTSTYYRFTTNDGLHTATAPSIEGPWTDQGPALPDGSSIDLPGNKDLWAPDLFHYQETYYLYYSVSQIGSKNSSIGVATSPSLDPGSWTDHGSIGIPTSPDYNRIDANLYYPSGGSPVLNFGSFWQNIFQFSMEPSLLKITGEAKHISQNTTTRPAGLVTGAQEGAYLFFWQGYHYLFLSGGNCCNEPGQGSGLAPAGEEYHILVCRSSEASGGFVDRQGRDCLNGNGGTLLLGSQGDVYAPGGQGVMFDPKLKMVVVYYHYVKPSVSYAYDDFFFGWNKLDFEGGWPRVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4T2</accession>
    <name>A0A9Q8L4T2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02176</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the nucleoporin Nup84/Nup107 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755184.1">
        <property type="nucleotide sequence ID" value="XM_047901324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4T2"/>
    <dbReference type="GeneID" id="71982054"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02176"/>
    <dbReference type="OMA" id="RYQGFCK"/>
    <dbReference type="OrthoDB" id="3098at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007252">
        <property type="entry name" value="Nup84/Nup107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003:SF2">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003">
        <property type="entry name" value="NUP107-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04121">
        <property type="entry name" value="Nup84_Nup100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5 7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="963"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="967"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="987"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO10818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="996" mass="113526" checksum="1A046320B824C36A" modified="2023-09-13" version="1">MAPATRRQTAGASSVKKAPPARKPRATRQAPPASEDWNFISRGGSSREDTNDQENHTPDFDMDGRNGGTIEPTRELPDVNEAVRPLREMAERVGAEVESFAETLDQFLDNLPTRNKFDAVLELADQFKGYAQHVATRLKEQHESAARRERQKEWEQKANISTQTTAFGAASSTTFGTTTTGKTAEQVRQMRQWQQEADIWELFRIMLEQHHNPDLRSIQQEKEDKLRSLGDVHRFTPEKDIWERFLVEDDLAKERSVVKRWLEQTAEHQESDIPGIMEELEKKGGVSKGLWTNGWVHTRVKIKGEKRLRTWPNNPGAALPQITRADDGALLVTNLDPDSPLRQGRNTEKKDAFAEKAIWIACWEMLRRGQSWEDISKWCKEREEGWRALSMGNVEPSEAHSLATWRNMCYAASTQNAGLANPYEAAVYGLLGGNADAAQKVAKTVDENLHVYYSAALVRQFDLYLEMHYPDRGPKNTRQSADLSKDPDTQIIELIMQLRKKPTTGREAIQPMKIIQSYLLANDVGSLIHTLGFAIAYTARQRGEADAMILDLKPFWEEDRNQPEAEVALSSQTLRIATHMGIMIRLLAGERAKKENHEREAEENVYVAYIQELRAAGKRELIPLYVSRLHASRYIITMAEILGDITSSTEQNMMLKLMRQYELDIIKIINEQLAFLMNSHMATTLEPDVRRSARIFEPADDATFYPGQRIIHGFFSEVLQEGDEAIVRSLRWFSLVEGYWQDTFSALSFALRKCLVSGRLACASEIIKEYPYDTVALRKAYQVLGRSINPFDYEGEPPCSRSTWETLKRTSRCYYELEMLTHALVALDDWRKKEAEYTRKILRMSAAPQDLKTAKDQVDSAMSDVLTRNLLTHPVTSDEEKDLRIVRREYIPEMIIAYNTVLHSAGNLITRHILVESMDLSVTVANDQYGLSEIILEAGRMRELMRSFANTAKAMLILKSSGKPYKPKKDREGKDLGIWEIGPQGRSAREGQDVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5T7</accession>
    <name>A0A9Q8L5T7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cryptochrome-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00553</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755710.1">
        <property type="nucleotide sequence ID" value="XM_047899701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5T7"/>
    <dbReference type="GeneID" id="71980431"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00553"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF9">
        <property type="entry name" value="CRYPTOCHROME CIRCADIAN CLOCK 5 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="593"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="669" mass="74836" checksum="A0AEB92B4AF60EAE" modified="2023-09-13" version="1">MSKPRVIYWFRTDLRLHDSPALKAALDLKPEVFFPIWCWDSHYVYRARVGVNRFQFLIDCQNDLSKSITKLNKKSKLFVMREPAVTLLPKLFKQWKVTHLVFEQDTDAYAKDRDQQVTKMAEDAGVEVIVKTGRTLWNPDEIVKANGGKPTMSIAQLQAAGAKLGEIEPSVDTPTSLPPPGDMKLNIEQTQPKSEPDINKKHRDGEEASYSAGIAGPNDDFAPPSLEELGMPAATSPHKGGETVILERLHKILEDEDYCGTFEKPKTSPAAFEPQSTFLTSPYLHFGALSCRYVSPVLTSPENNADIPIQFYHKVQSIIDKRKKANKTISTPPESLAGQLLFRDMYFAAQAALGYAFGQTYNNPNCRFIPWHLPSKIDLTTKLITGSYEVDDPVKETEFKRWSNGTTGFPWIDAIMRQLRQEGWIHHLARHSVACFLTRGGAYISWERGAEVFEELLIDHEAACNIGNWQWLSCTAFYAQFYRCYSPIAFGKKWDPNGDYIRKYCPELKDYPAKHIFEPHKAPISDQKAAGVRIDGDGTDKEHDGLALYPKPMFDFSTQRDICLQGMKNAYHVGLYGNSPKMLDGTWKELFEDDAEGPTEGGKGEPGGLGKGEDGDGDGGGEDGGKEEEVVKTPKREAGGSGSVKKSPRGHKREHSQSTLDFGKKSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6M6</accession>
    <name>A0A9Q8L6M6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756060.1">
        <property type="nucleotide sequence ID" value="XM_047900315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6M6"/>
    <dbReference type="GeneID" id="71981045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01167"/>
    <dbReference type="OMA" id="RFCSHAV"/>
    <dbReference type="OrthoDB" id="5387413at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="29442" checksum="BD80A4CC0960A235" modified="2023-09-13" version="1">MSSSRRHSVRPVIVEVKPDNAPTSNIAPSSPSLRKAVRFAPRSEDRASRPLTSTEAWSLYHFESHARHCPACYCPLEVYRRGEQLCPIGHGLAQDVALHCYHLNGEVYSTTKDSNSNKLVRVEVPHGYSQLRSLLRSMEHRLRSHRATPLVSYDRSYPISARKSWTPETEPENVILETGTSSRRRSTHRPVRYSTVVVVDNAIEDVSATTSTKERRGTLYEKEMQRKPKDYRVEIREPSESRKERRRHRDSGVSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6W9</accession>
    <name>A0A9Q8L6W9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mannose 6-phosphate receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00428</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756280.1">
        <property type="nucleotide sequence ID" value="XM_047899576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6W9"/>
    <dbReference type="GeneID" id="71980306"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00428"/>
    <dbReference type="OMA" id="RTKSTIM"/>
    <dbReference type="OrthoDB" id="4504960at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028927">
        <property type="entry name" value="Man-6-P_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF0">
        <property type="entry name" value="MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02157">
        <property type="entry name" value="Man-6-P_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01404">
        <property type="entry name" value="CIMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040477128" evidence="11">
        <location>
            <begin position="21"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="12">
        <location>
            <begin position="31"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="38733" checksum="DBE43BB8A016623E" modified="2023-09-13" version="1">MNLLYYSLAVYLSLTSPVLAAASKDSKDGEKPCTITSPTSGSFFDLSSLQLLDPKVSKTKHPREHSWNATGYDLGYNFTVNVCGPVIENVEDVVGVEKNLWQNVSAYYKHDGKTYSLGQQNSELVMRGRKLVLNYTDGSPCESVSKRSAPLLNNLETREIVGGGDKKKSKDKDDDEGNDSDSKKKPSSNGKKKKSTIISMLCDRDPLAPTFALSFVGSLDECTYFFEGRSMAVCATANTSSGGSLNPSGVFGVIMVIAIAVYFVGGCVYNRAVLNQRGWQQIPNYSLWAGIFGFFRDLVMILTSSCARFLPLRRGYSRVNGGIGGYDRRGRERGDSDAENRLIDELNEEWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7B6</accession>
    <name>A0A9Q8L7B6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EKC/KEOPS complex subunit GON7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_01250</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GON7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755894.1">
        <property type="nucleotide sequence ID" value="XM_047900398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7B6"/>
    <dbReference type="GeneID" id="71981128"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01250"/>
    <dbReference type="OMA" id="PHESKAQ"/>
    <dbReference type="OrthoDB" id="2288868at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Gon7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO11528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15382" checksum="35C304AB12326935" modified="2023-09-13" version="1">MQQATTSGAQAKLRLHLLPADFNVVASRSPPHLDHNAQSQQTMSPSSLVAHYKSPHATQSFSSELPHLPEDGANVEQQKTAYLAALRANTTKLQDEVNVYLTQKMDEDKVAESARGKSSKDMEEREENMYGEEDPEETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L897</accession>
    <name>A0A9Q8L897_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01014</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO12664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757030.1">
        <property type="nucleotide sequence ID" value="XM_047900162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L897"/>
    <dbReference type="GeneID" id="71980892"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01014"/>
    <dbReference type="OMA" id="YLQMLPK"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
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    <dbReference type="InterPro" id="IPR001107">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="100"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
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        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
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            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="46443" checksum="FB8BD38604BE6981" modified="2023-09-13" version="1">MATAAKAAEPAMSFLASSTSTSISTSTGRRALSRRSMAAIQNSRYPIVYAAARATQRSAFSTTPKQALPSPGESLFRSSASSSSGPPSAYFQRSSLPANTIVKFVPQQTAWIVERMGRFNRILEPGVAILMPVIDRIAYVKSLKENAMEIPSQSAITADNVTLELDGILYTRVFDAYKASYGVEDADYAISQLAQTTMRSEIGQLTLDHVLKERAALNTNITQAINEAAADWGIRCLRYEIRDIHAPGPVVEAMHRQVTAERSKRAEILESEGQRQSAINIAEGRKQSVILASEAIKAEQINAASGEAEAILLKAKATAAGVDAVARSLSDGKQYAQGAVSLSVAEKYVDAFGKLAKEGTSVVVPGNVGDIGGMIASAMAVYGNVSSAQAKVQAQKLVGDGKSDASSETTSGEKLSKNEMQQKVLESFDRTQERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8R6</accession>
    <name>A0A9Q8L8R6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein rnc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01402</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757303.1">
        <property type="nucleotide sequence ID" value="XM_047900550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8R6"/>
    <dbReference type="GeneID" id="71981280"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01402"/>
    <dbReference type="OMA" id="SIAKEPH"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="40"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="126"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="276"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="37781" checksum="A145BC8BA752D9B3" modified="2023-09-13" version="1">MSAEDNTSPAVDSGIDNLADKIGALNTDDRPRTEEEYAEAQLTLRAIVTSKEAGVIIGKAGQNVADLREKTGVRAGVSKVVPGVHDRVLTVTGALTGIAAAYGLVADSLVKGAPQMGMGGVVGTPNTHPIRLLISHNQMGTIIGRQGLKIKQIQDASGVRMVAQKEMLPQSTERIVEVQGTPEGIQKAVWEIGRCLVDDEQRGYGTVLYSPAVRVQGGGPPLNGTGAPPGPGAGYGAPRSYNRTGNGADFTGAAPAPYSPRRQEGPPPTTNEDGEDIQTQNISIPADMVGCIIGRGGSKISEIRKSSGARISIAKAPHDETGERMFTITGGPAANEKALYLLYENLEAEKMRRSQIPEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L953</accession>
    <name>A0A9Q8L953_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <authorList>
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    <sequence length="328" mass="36128" checksum="C4497729EF101906" modified="2023-09-13" version="1">MFIFRHGGRFAALAARPVTSTPQRFASKISIPFAPPPFPVVESCPSPTCGCRESPSGLDIEREQNISGSMATYAEQILISTGRNDWKSKIEDEEEAVLVRQLKKHLTRGGKYVAPYHNVMITNSSFPPSSSTSAASAFLLPSFRYIPAIPTDDNNIESFIKAFVLPEKLHNFYSSLPLEQRNKLLRQPEHQGQFDSRPVNEIVILVCGHGGRDERCGKLGPVLIKEFEEKLQAQNIAILKSPDEVSEDKMTARVGSISHIGGHKWAGNVIIYIPPTLKGNALAEKGIWYGRVGPEHVEGVVKETVLGGKVIKEFFRGGIGRGGEILRL</sequence>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </evidence>
    <sequence length="1058" mass="117593" checksum="93964FDDADB666EB" modified="2023-09-13" version="1">MPYDPNAHYSGPGGFHYGTPAQQFGQAKMSQAQRQAAGQAQYPPQGSNSIYSQPVPQQPTQYQQPVDYSRMQYSTSQYQGHSSFYRTPQSVPHSQSVQQPYISPPNRPSQIQQNTQYSPDPLQYYQAQSNPRQATQPPGRQQYQQQQAPPQRPAPQQSRPQPSPVAWQNPPPQHWPKFPPPPDQQSFAHQAQRQQNVQQSFQQNQHQTQRHPSQARPSSATSQRSSIGIPQPSPQPAPRSLQARHSPILARSPSANQPQRQMPPAPRPQQIQQSPRLPNALPKPPVVNQVPVTPKAMPQHQAQHQPPSMYPPGTVDPTMLQRRILTPVIPVQKAPPKAQQAEYASSGHSPKRRRSNEGQAIPVCEPSKETLQYSWTQRVKQTAPTSSPLTELASSQFPPTPTPANIDYQAVLLNLSNEYISAAYNMSSTLATPEVSEEQLDDYHSLLSTGMGCLESALKNFRAMDARMEARIRLRLASLLFEETDNDTEAEEILSKGLSACERARLPELKYAMLHLLARLWYKGGKSKAAMKAVEKHITEVEKLNLVHWIYAFRFLRVSLGLQADNSYVESSALVRQLTAINAVADRQQDVAVQIVASGMEALIHLRSRTPDSVDLAQRALAAARMHQMSHEMASMPQATALLNYVDLGCSIMHFKPEQASAKVELMQADLNSMNRQSSWCNDGSWHVQLGAIRTSSANIDADTGGVVRIFDGQPSLVFKWFTKIQVYILTYMFSSLSSMHKNANPEQKAEALLNEALKLSKLPIEDAQQSMSAASAQYNTQRLLRVNLRLYVIFAFCGRSDWDKALKGIENIRKDIDELEEDPGADITSLIAYLEAVCKHGLADLQGALDLYHSPHLKVPTQMDAKSAAGSISPIRVLAALNSIMIMRHFGRREEADRLLTIVEPACLVKSTSYGSEYGSKAIESAFMILKATEPRDRAADNQILKTKQHLQVAVNAAKIALNNQLLCIVMNIMTDLFFHNIVGDQAEKSARAGRTLAKKSQDKLWTAVADRMYGNTLEKCGKGAEAAAVRREAQEAMERMPESLKTALLAEEMGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAT4</accession>
    <name>A0A9Q8LAT4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757709.1">
        <property type="nucleotide sequence ID" value="XM_047901979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAT4"/>
    <dbReference type="GeneID" id="71982709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02831"/>
    <dbReference type="OMA" id="SWKPAYL"/>
    <dbReference type="OrthoDB" id="2157866at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd13298">
        <property type="entry name" value="PH1_PH_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13299">
        <property type="entry name" value="PH2_PH_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="59"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="319"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="47811" checksum="9C9843977C888C31" modified="2023-09-13" version="1">MADVAPQGHPRPIVPPNLPPPSIAMPGATTTPLQNARIHGLTLDTFSPVTQSGSYDFDRIIKQGQVLKRTRKTKSWKPIWIVLRPTLLSIYRDKQESRLRHQINLSDLTAVARQKDPKRKDKHVFALFSPSRNFHLEASSDKDAQEWVELVRREARMDEQEEEMHLASPGGGNASYRGFERSIDAHISPSADERAAGYSSSDAEAFGQSQPLPRHRDRTSMTHSNRRASQMEYSGAEHASYSDFSDSALGATARMSALSLAYPDGRPSTSSTQQPHVGSVYGSAPLRPSMGARNASQMSGIGIILDEKKSTTTVSDEERIVCNGWIYLLKSRSGVRQWKKVWMVLRPKQLALYKNEEEYTAQLIIPFSNIIDAVEVDSLSKTKTSCMQVLSEERNYRFCALDEESLTKWLGAFKSLLSKRKAKATATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAU4</accession>
    <name>A0A9Q8LAU4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar segregation protein pep7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758456.1">
        <property type="nucleotide sequence ID" value="XM_047902132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAU4"/>
    <dbReference type="GeneID" id="71982862"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02984"/>
    <dbReference type="OMA" id="DDVHQNL"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15761">
        <property type="entry name" value="FYVE1_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="9">
        <location>
            <begin position="359"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="598"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="675" mass="74686" checksum="709859AFB971ADD1" modified="2023-09-13" version="1">MAARRSLGGGRVLGSGNGLAPPSPATSSTATPKPIHTVRSPGLLSPSDSSVSLSSLASSTPISTDHEDLTSRIALDEHASAHAAAAASNRLVCPICSEEMVTLLQLNRHIDDNHANLEEIEQDEAKTWFKQQMTKAKKFQPLALINQKLRGLEVFESNNDMSAPMQAIQTAVAGARESSPAPVPTPIRKEPETPDPDEVVTRAHWQRPRGFDDCSDPLCGKRLGPANGQVNCRHCGKLFCEEHTMYQMKLSRSAKHEPVRGLWCRVCEACYKSRDGYNDHHGFERNHLDFFKGARRKTVDKQYLETSRLETRLTRLTQLLADPPPDQGQSTTNLLWSSLSGNKPQIRALEQSIVPWEEDTKVAECPFCQQPFSQYSLRRHHCRICGRVVCGDPNTGCSSDIGLDVDSKKNGAKVAVDVRMCKDCQRTIFSKADFARELSTKSPDQRAYENLLQFEHGIRLLLPKFQRLLAPLQDPEHPPTPAQLAEASKIRKRLTDAFTQYDVASRRIRDLPTTSPTQEQLQKAIYSKALTFLHTHMLPLKALPKILKHATPNGLRNPPVPSNGKPQGALAAIKYNAITNGLARPGSSRTSSESSVAVTALEAEEKELKNRLIVLEEQKFFVSEMIADANKRRKFDEVSALSQNVEDLSKEIDQIQSQISGMDFAGAYAADGVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC64</accession>
    <name>A0A9Q8LC64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-methylene-furan-3-one reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759047.1">
        <property type="nucleotide sequence ID" value="XM_047907751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC64"/>
    <dbReference type="GeneID" id="71988481"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08603"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051603">
        <property type="entry name" value="Zinc-ADH_QOR/CCCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44154:SF1">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="2">
        <location>
            <begin position="31"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="16700" checksum="8EA2626EA62B8517" modified="2023-09-13" version="1">MPQQKAIHYTKPGKASEVLALTTIDIPKVEANDLLVKLKACAVNPVDTKIREGKFPASDVMGYDAAGIVEEVGSSVKDFKKGDEVYYSGAMGRRGSTAQYGVIGYRMAGHRPKKFDWVESACLPLVTVTAWELLEEHFNLPQDDPTGKQKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCB7</accession>
    <name>A0A9Q8LCB7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08508</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759267.1">
        <property type="nucleotide sequence ID" value="XM_047907656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCB7"/>
    <dbReference type="GeneID" id="71988386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08508"/>
    <dbReference type="OMA" id="LPFAPNM"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000002">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="496" mass="58153" checksum="13305DD2C1AC4211" modified="2023-09-13" version="1">MDSPAVNRLFRRLATHRFCHETRSLAAPVVQAQWRSQSTHTLPSGKKAKTTAESSWQQRTDHFPSDKAEEFKRYPNVTSDQLRTRRERPRRVKMLMRDFIEDSLYNPHYGYFSKNVTIFSPGAPFDFNKLRDEPDFYRLLGERYTQFEDKLDEKEYNEARQLWHTPTELFRPHYGEAIARYMVANYKLTLYPYHDLVIYEMGAGNGTLMLNILDYIRHTDPEVYARTKFRIIEVSSALASLQAQKLQATASSRGHHDKVDIINKSVFDWDLYVPTPCFFLAMEVFDNFAHDVLRYDPFTEEVMQGSVLIDSDGDFYEFYSRTLDPVAARFLRVRDAACQDRQYPHPLRPSKILRSIRHRLPLAPNLTQPEYIPTRLMQFFQILSTKFPAHRLVTSDFSGLPQAVAGYNAPVVQTRYQRRTVPVRTPLVQQGYFDILFPTDFAVMEDIYRAVTGRLTRVMTHEDFFQRWAYVEDTQMRSGENALLSWYKNASVMLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCE7</accession>
    <name>A0A9Q8LCE7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTF2-related export protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759238.1">
        <property type="nucleotide sequence ID" value="XM_047907749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCE7"/>
    <dbReference type="GeneID" id="71988479"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08601"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="16285" checksum="7A94D72CD84AA08A" modified="2023-09-13" version="1">MSSPTISAATTFLNTFFTIFDTGNRADLIPFYTPTARLTYEDVTYNNAPDIVTFLVEAPKKIQHKRAKTVLEQVNERGDVLVLVTGVLEFGKRGTRTNFATTFVLHRSEGVDMVGEGEGEEEGEFVIGRQVSSISFEGDEELDLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCM3</accession>
    <name>A0A9Q8LCM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759432.1">
        <property type="nucleotide sequence ID" value="XM_047907260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCM3"/>
    <dbReference type="GeneID" id="71987990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08112"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040427996" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="94" mass="9724" checksum="9729570EF5D1FC7B" modified="2023-09-13" version="1">MQFKALTLLSLSALAIAAPVETSFEEANPLMARTGSTICCPKGKKSGCITLAPGKAPPANTDVYKDCANILNIGLVNVSSSLPSRLMSATTRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD67</accession>
    <name>A0A9Q8LD67_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl hydrolase family 92 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759643.1">
        <property type="nucleotide sequence ID" value="XM_047906924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD67"/>
    <dbReference type="GeneID" id="71987654"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07776"/>
    <dbReference type="OrthoDB" id="449263at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF44">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 92 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040496682" description="Glycosyl hydrolase family 92 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="3">
        <location>
            <begin position="324"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="765" mass="83774" checksum="0894B307C3B03071" modified="2023-09-13" version="1">MAKSFLLLSGLVHSINAQARLSDHVDPLIGTECATAGSTMAKPGIDTSFLGLRNGTDCDGRRRMDLLRRCRCWGGSEGVNLAGNNTYSQNRLLELEMASVGKFTTTLVDGVRIGIASAEKSGVVRYTFPSGGQEGSMKLILDPSYGSTEAPTSPAGSNSDDAHALLDLTHVLSSYSIQDYSQKFLRGNLHIRTGSNDQPSYYGSASYTGLAATDAYVEQQTLESVAGAGTFNRPYDPVVPLNFTLRPSPQSARDAVVHTGSAQGLGALFSWSRTGSNSTEASVVESRIGISYISASQACSNLQTELPSSITFKDAILDDGSDSSTNNTLKRMLYTALYQTGLMPTDNTGENPYWHTDDDDEPYYDDHHTLWDTYRTAMPLYHLLFTTTYSRVLSGLVSIFKHEDLLPAGRPGNWNGRVQEGTHADMVLADAFVKDVVIIEGQEGDKILNIPWTDAHSAQLRLHYITRNRSRSISRGLEYAQKDFAIYSMATGLNHTSDITSFRDRADWWQNQWKPSENITLPGEAGIFTGFPAPCNSDGSWNYTSYKPVTCDNCGWSGDIYEATVWETAFSAAPHDMARLIDLMGGDDDFIKRLDTFVPGLGQGTGNANNDAGTAVFNLGNEPSFMTPWLYHHVPGKQWKTVNQTRAIIDQFYSDERNGYPGNTDSGALPSWLPIYLIGAPRFSGLRVKLFAGTGREAVLEIKAEGMANDKFYPQSVMLNGQRLDRSWISHDELSKGGTLSSEMGSEPGDWVSGERPPSLSPWMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD80</accession>
    <name>A0A9Q8LD80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08093</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759450.1">
        <property type="nucleotide sequence ID" value="XM_047907241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD80"/>
    <dbReference type="GeneID" id="71987971"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08093"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF1">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="58285" checksum="A95989471721007C" modified="2023-09-13" version="1">MSDPETPSKTADDATLALLRKEALCELITWETVLALFSQALENGGPAGAVYGYIITWFSTMSVYTVISELASMAPIAGGQYYWVYMMAPPKYKRISSYIVGWLTTLAWVATVATETLFAELIVQGILVLDYPEYENKMYQGTLLTWAVILGCIFINVVIPAWLPRFEVFILVFHLAGFVAILVTLLIMTPSLGSAESVWLAINNGGGWPTQGLSYCVGFLGNVATFVGADASVHLAEEVSNAAVNIPRAILGAMLINGSIGFAMMVTVLYCPGDVQTVLETKIGYPFIQVFYDSVRNVAGATVMAAVVLALTWACATGITTTASRMTWSFARDRGLPFSNFLGRVSSRSKVPVNAVLVVAGIAALLSLIYIGSYTAFNDVISLTITGFYGSYLLPAGFLLYHRIKGNVLPRGTELDTSPSDANAKEVKTGAAEEVTQDVDGVEVVQARLVWGPWHLPGILGIINNVYACVYMVFVIFWSVWPPATPVSASTMNYSVVVTGGVMILSAIWYFIGGKKQYQGPLIDDEVASIMRAGSTISVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDC1</accession>
    <name>A0A9Q8LDC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Altered inheritance of mitochondria protein 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Found in mitochondrial proteome protein 29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08158</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIM9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759510.1">
        <property type="nucleotide sequence ID" value="XM_047907306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDC1"/>
    <dbReference type="GeneID" id="71988036"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08158"/>
    <dbReference type="OrthoDB" id="2831558at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051035">
        <property type="entry name" value="Mito_inheritance_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="399" mass="44534" checksum="09677474016B3ED9" modified="2023-09-13" version="1">MAEGSFNKAFLLTMDDGKELIAKLPNPNAGYGHFTTASEVATMDHARNVIGVPVPRVYAWSSSVDNPVGAESVLELNCIGFGTRLPIVQKAAIIHKLVSYEALFASSDFPKYGSLYYAKDLRPTDNPEAFNVSLGQDTKLPEFAIGPTTDRNFFENGRAGATANQGPWSTVEAYNLAIAARELACLRKSSEFPDPQGFYNGPRQYQQSLETKMRTLRNYEKVAGYLKPADPILSKPVLWHTDLHWDIIFVDENDPKIITAIIDWQAVHVAPLFAQARHPTFLEFDGEIPDTFDAEAITLPDNFERLSETEQQTAKKLRNAQILWKLYEVELVRQCEDVERAIRFGRGLLGRIPSLAGNIFSDGELLVEDLLMSLQQEWNQVVDDPVANPCPLSLPAVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDJ6</accession>
    <name>A0A9Q8LDJ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759766.1">
        <property type="nucleotide sequence ID" value="XM_047907153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDJ6"/>
    <dbReference type="GeneID" id="71987883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08005"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="86"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="573" mass="61451" checksum="5260FD2A1A1C2122" modified="2023-09-13" version="1">MAARRAISSRTLQSLTLRPTVTRASRVVSKMPQNGNETANAVRRLHATSQQLAATTTAASSPQQYPTTHEKVDQPLNTQNFIDNKFVASDATQWIDLHDPATNNLVTRVPQSTDAELKAAVDSAQKAFPGWKAMSVLARQQIMFKYTALIREHWDRLAASITLEQGKTFADAKGDVLRGLQVAETACGITTQITGEVLEVAKDMETRSYREPLGVVAAICPFNFPAMIPLWTIPIATITGNTCIIKPSERDPGACMILAELAEKAGFPPGVVNIIHGSAKTVDFIIDEPRIKAVSFVGSNKAGEYIYSRCSANGKRVQANLGAKNHCAVLPDCNKNQALNAIAGAAFGAAGQRCMALSTLVFVGETKDWAPEIAERAKGLSMNGGFEEGADLGPVISPQAKERIESLIASAEKEGATIVLDGRGQKPEKYPNGNWVGPTIIANVTKDMTCYKEEIFGPVLVCLNVQTLDEAIELINANEYGNGTAIFTSNGATAGKFQKEIEAGQVGINVPIPVPLPVFSFTGNKKSIAGGGANTFYGKSGLQFYTQQKTVTSLWRSEDATNTRASVNMPTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDY9</accession>
    <name>A0A9Q8LDY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760022.1">
        <property type="nucleotide sequence ID" value="XM_047907865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDY9"/>
    <dbReference type="GeneID" id="71988595"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08717"/>
    <dbReference type="OMA" id="LACDIFY"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="34419" checksum="D68C91820C89A2AB" modified="2023-09-13" version="1">MAIISDENPVRTEYHVAADVVSLVVSSLALPVVALLVWGRWPKGGREGLTVATALCLLCYVTTFLYIVAVTLMMHVQWERTEELCNAMMIVCMLLHNSSKASEFAFLIERAYVISWKRKPRRKTPEYVLSSLLIILPYIATTIVAIRFRIAYMVNAQICIIGLEYFAIGSMLSVELLAQLVLTLRFLVPLITVHRKGNGLMLPLRNAVVRTVVGCAITMLLNVAVKISLLLFDGMPAWLCYLGCKVEALLAACVLHWITKPVLADEEREAQRRFGDECDDDSSDSSKEMDLQEMLGLPAGGHATDRSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE10</accession>
    <name>A0A9Q8LE10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759329.1">
        <property type="nucleotide sequence ID" value="XM_047906940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE10"/>
    <dbReference type="GeneID" id="71987670"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07792"/>
    <dbReference type="OrthoDB" id="3921930at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="62160" checksum="A16B98BFAC0D4932" modified="2023-09-13" version="1">MGTYQYTPLPEGKHIRVLTILPNAAKRPRIDCTIETVTLDASSNYTALSYTWGMNEDGDASLCEELYISNQRLPITRNLYQGLLRIREKTTPVRMWIDAVCINQQDIPERNAQVRFMPSIFSEAAAVVVWLGEGTTEQDDEDAASLFDVMAGAEWDLSLFCDDDASQVLSGQTRSPIRGNFDIEDRLSSLDRCSTGIIVAMRALAGSLNWCAGRSDMLFSTLVPRDLTMWQHWMSLSKIIAALWELYHARPGAVVMRWGHCILDLQHFRDASATWYSFAGVSRRYASRPNESDRSSGEDLLHQIQTDMLHRNMFNFPDCVTVPALGQKQRLPESLLIHLLRIYSHLRCLDDRDKLFALVSLVPSAEVELPVDYSLNFTQVCIKFTIWLLRKGHLAIVLHQLGLTTLDSELPPLNAPSWTFNLRKRIYTTAESDNIPVHRVDEAGLLCSMIFAGTITNIDLARNTYGGELEVVDSSGTLHTVDRILWDSKLKLQSDDCLFVPVDAAGSGTQYGIFMRRALQHDRYRIVDVAMLRASDLSMLDLGHPEPVMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEL8</accession>
    <name>A0A9Q8LEL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04250</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760338.1">
        <property type="nucleotide sequence ID" value="XM_047903398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEL8"/>
    <dbReference type="GeneID" id="71984128"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04250"/>
    <dbReference type="OrthoDB" id="1288932at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF3">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="35"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="299"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="63867" checksum="77D08EACFB2A113F" modified="2023-09-13" version="1">MSSSPAALAYHEPGIITILILASFLLLENAINWAFDKLLFCGLLGQIAVGVAWGTPGAKWLSIDVENTIMQIGYLGLILLVFEGGLAADLKTLRSYLSLSSIVALIGISAPIGLSFLLQSFMEITPVQSFAAGAALCSTSLGTTFTILSTSGLSQSRLGVVLSSAAMMDDLVGLVMSSIISSLGRHSDFSATTVIRPVFVSVAFAAVLPLICLYIVKPMTRQTYKLIKSKRGTQFHRLLTTESAALVLHALVLAALVTASSYAGTSVLFAAYLAGAAISWWDGLCFELRNADAQNTLEPVDGTDLVGSSQNGESSGAMDSKAHSMPQKPRAHRKQSGENNTSSSPKPREPQQPVPTPSTRQAVPSYDHLRGTHIFEKYYLPALQTVLKPFFFASIGFAIPITQMFSGTVVWRGIVYSIIMVIAKLFCGLCLIRVAGPAVSLKFLLKHLPKTISGCWPLIRTQSKTPGTSSTRGGPRSQSTTTVATAAPKQRSSPRIAKPTSLYPAAMLGSAMVARGEIGFLICSVAESDGVFGATENGQSSELFLVVTWAILLCTLLGPIAVGLMVKRVKRLQELERSIQTGKEDPLGIWGVIPSQAASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LET3</accession>
    <name>A0A9Q8LET3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760449.1">
        <property type="nucleotide sequence ID" value="XM_047904315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LET3"/>
    <dbReference type="GeneID" id="71985045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05167"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="198" mass="20033" checksum="F5F72C3B087D1024" modified="2023-09-13" version="1">MYQYQYQGYGNTLPKVSEDNYGLFASRESAPYGTSYSRTTSGMPQSFGGLGNARGMASRAPRETTTVSLAHDSNMRDWNRFQGGGWNGWGQFKSADADAAWENRVSRGGPKSDSSWEARSASLGGWGASGSGGGVGEGRGMGAFGGCGGGVSSYGGGGSRGMGAFGADRSSSGGSSYGGGVGPSSAHAAGGFLSSYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFB8</accession>
    <name>A0A9Q8LFB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760768.1">
        <property type="nucleotide sequence ID" value="XM_047904357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFB8"/>
    <dbReference type="GeneID" id="71985087"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05209"/>
    <dbReference type="OrthoDB" id="5336600at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF4">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="24777" checksum="52AB4F5CE93973C2" modified="2023-09-13" version="1">MSRPVALILGAGANIGQGTADAFLVEGYSVALVSRKPDNTRTAPNTIKIAGNLSKPESVREIFAKAEEQLGIPEVVVYSVAAAFTANYKLDPLSLSFEHFSRDMNIKTYSAYVAMQESVKSFAQLPEAAFKTFIYTGNLLNEATMAGLMALGTGKTATAHVIETAAAAYQDRTLKFYYADERLSDGTPPFMNIDGEAHGKLYVELAGHKKQGPWQQTFVKGEGYRSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFU5</accession>
    <name>A0A9Q8LFU5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase</fullName>
            <ecNumber evidence="3">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="3">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="2">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="2 3">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760989.1">
        <property type="nucleotide sequence ID" value="XM_047903680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFU5"/>
    <dbReference type="GeneID" id="71984410"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04532"/>
    <dbReference type="OMA" id="VPNTLMH"/>
    <dbReference type="OrthoDB" id="3341590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF20">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="4">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="442" mass="49629" checksum="1BCC53353ECEA891" modified="2023-09-13" version="1">MAHYAGANPMAGGQESLDSFFGMGKSMFELLPGYDCPAYADYMDTRYHMLDKSHELPNSICVFEYTADHLLSRHTAEYSVTASRNTYLVVRSVSTVGNYDYAIDYIFYMDGTIEVKVRASGFIFAAFYRANKTAGEDEYGHRIGEAVSSSVHDHVINFKADLDIAGPKNDMVRLALEPITRTFDWDLPEIKERNTMHLVEYPVTEEIGLDWPKNGGEFYIVYSSAEKNAWGERKGFRITSGTGMGVTPHLTILNSTTLGDSARWAEHDVWVLRQKDTEPRSADPLNYLEPNNPIINFNNMADHESLLHNETDSTHDGDLVPYFNLGAHHIPHSGDVPNTLMHTSASSVMFVPHNFHDRDPSRESVQGVRLQLKGKKDSGGFAGDLRTRSEKKEAKAKYFGGTYEQGMKMPLEALEPDVKGYRTEQHEITDLGFNGSAARVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGL0</accession>
    <name>A0A9Q8LGL0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-binding monooxygenase moxY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761394.1">
        <property type="nucleotide sequence ID" value="XM_047903625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGL0"/>
    <dbReference type="GeneID" id="71984355"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04477"/>
    <dbReference type="OMA" id="ANIWSEM"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="68491" checksum="1CCAE0603FF1DA46" modified="2023-09-13" version="1">MKEIRYHASEALENRRAANYIPTFVYDGLPDPSGRPDVEIRNDFFGTRRKLRIGVLGAGIMGLQFLHSAEKLKDVEIVVYEMNEDVGGVWLTSKYPGCRCDIASMVYQFSWRANIWSEMYAPAAENLAYIKTVAKENDFYRFIKLRHKILSAKWTDDDSLWTLKLKDLESNTEFDDKVDVFLEFNGPVSNPRLTPLPGIEHFKGEVVHPAHWKDETTVKDKRVALIGYGCSGVQIGPNIVNNVSKLYSWFRNKTYVLPPPNQAFSAEGGNNFKYSEAQKELLKDPDVYLAYRKAIEDGFNRRYSYLINGGKVGNEVQEMVVKYMREKLKSKPELFEAIIPHDFGIGCRRQTFAYGYLEALTHPKTTVFLAPPQRFTDTGLMDADGKEHPDRPLNGEIVAEKWKDLLSPPCYMACMPKGMPNYFNPASAFGPLPQGNFYQSSEAYAEYIVKMIDKVQLDRILSFQPKDIAVDHFVRHANAWMKRTALTGPCVAWYKGNDGTSKPPSLWPGERNQFIKILQMPRFEDFDLRYENADDMFGYFGNGWYLETHGTEDGDKSWYMGKPKRHVGQDIIEKLRGTDPSVGRAGVEILVKTGEDGQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGR6</accession>
    <name>A0A9Q8LGR6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-oxoglutarate-dependent dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761477.1">
        <property type="nucleotide sequence ID" value="XM_047904030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGR6"/>
    <dbReference type="GeneID" id="71984760"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04882"/>
    <dbReference type="OrthoDB" id="406156at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="205"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="418" mass="47623" checksum="A55595F34EB2E1AE" modified="2023-09-13" version="1">MAPTAPFNPPSSELPGKPVVPQWIPPPLTQEKENFAELKSIGLSLLDSDDPAVVDSLVQQVKTAIRNDGFLFLENYGISLEQLHRQFALAQCLYANISEEDKQRLLFDPETGLWSGYKHPYGFKRQRGVPDGSEQFNWYPREWQDINHTPTCLHPLMDEIESFCNYLTKSVNRRLLTLFSRVLELADDYLWEKVRSHGTPTGEGYFRHALFRLVEKQTAEASKDLRMHGHTDFGLTTLLFSVPISCLQIWGRDEQRVSSFHIVNVVLSKARRWYYVPYKPGTLVINIGDTLEIVSGGHFKATRHRVFKPPVDQLNQERLSLVLFNSSMGSLRMTPASGSPLIQREGCVEDQGVYKEFKQRTLAGSLVPTNKEWHEIQIATARDPTDTVRNRVGADQVVIDGKLMQQREYMGVKVVLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHG7</accession>
    <name>A0A9Q8LHG7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761610.1">
        <property type="nucleotide sequence ID" value="XM_047904713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHG7"/>
    <dbReference type="GeneID" id="71985443"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05565"/>
    <dbReference type="OMA" id="WLRIITH"/>
    <dbReference type="OrthoDB" id="3649037at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="583" mass="64884" checksum="D2EC4CBB6B5B46E4" modified="2023-09-13" version="1">MSTSSAPAKKKKVCYIIEKLSAETRINIYKHIFGSDSHASFAPLDSSEGVATSDSPTAIPTAIFAVNRQLHDEALETFFNNKVIQVTFSQLEDLLQQTSFQAFVRDIEVMACDQAHEARAVQNVLIKVQGLPRLRSITILSDYLAFTGAPDKHVTVRQWTSAVGLGIPTCTDIGRYQLHGAYSKVQFHHSKILAMWPNVRTTPDDYDALGEAEEIQHHWSIAEYVSNLMAWSSHSSLRLWVGLYESAKAHAASEDAADLDDNEALHKGMSFGSWLRIITHRRPDVPFTLRGQDSAVPLRDLGAQHDPITLESATELLAMNIATYTKTGDLEYGPGDEYTKPRWSELGEKSEGEIKAEWYPIAMRALEEQRFVKDPLDQHRMWEIDTVRKMILSNEGWTNAFGGTDKIDSATKPVLQQIMYLILATGGVEISDEASQESESWSKALLVKYLRHCLPDTESSDWDDVELKTLRQVFFLALALMLVSSRQKAGAGAAGGLNNTEDISSDSKDKTSTEDQQAETGGEDAENRIQKTDDTKAVQEEDSDISQYFLAKAEPALIAAMQLQFEDKFLDEDEGTTATTMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHP6</accession>
    <name>A0A9Q8LHP6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_06269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761973.1">
        <property type="nucleotide sequence ID" value="XM_047905417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHP6"/>
    <dbReference type="GeneID" id="71986147"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06269"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO17607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="86" mass="9753" checksum="978F70252ABD90C2" modified="2023-09-13" version="1">MGVPFEALLPYAVCIGFFGLTGAGLSKIRHMQNGGKRGRHSVDQWDRQMMDRDRRLTGFLRGQTDNVRAPAGFELSNPWRIEKGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIC7</accession>
    <name>A0A9Q8LIC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762294.1">
        <property type="nucleotide sequence ID" value="XM_047904699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIC7"/>
    <dbReference type="GeneID" id="71985429"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05551"/>
    <dbReference type="OMA" id="IYMSETQ"/>
    <dbReference type="OrthoDB" id="17687at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000021">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000015">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="297"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="721"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1128" mass="124289" checksum="64D3DA7D49FED975" modified="2023-09-13" version="1">MFLQNLVQKAQSLIDPAVLPGPLGNSSSGRPSKAQLFRHQFRLPDSQNPLYEITAELTLPTKKRDKSAPSKNWDKSNWDRERGTHYVGQLHLSEQFLCFSTVQTSFVNTASTSASSTFTGRTHGTGPAGNGFTLPLCAVRRVERLHTQSYMFALSIATWNGFEPGNGDDKPGAPAPPKLTVQLEGSRQQCERFCDGLKRGLRQGIKEVDNMRTVAQECCSEYFLYDEFEATPAENKPDGTPRAAPDTGLGTIFKYPGNARRLRDRSKMRLWHEYLKENGRNTTLVRQPDFHRLIRVGLPNLLRGEIWELTSGSFYLRLQKPKLYQETLAKHEGQGSLAIDEIEKDLNRSLPEYAGFQSEEGIGRLRRVLTAYSWTNAEVGYCQAMNIVVAALLIYLSETQAFYLLSILCDRLLPGYYSTTMYGTLLDQRVFESLVEKTMPIIWDHLVKNDVQLSVVSLPWFLSLYINSMPLIFAFRVLDVFFLEGPKVLFQVGLAILRVNGEELLDATDDGTFISVLKNYFARLGESAHPKSENPKHRAITNFQALMVVAFKEFEGITQHTISEQRSKHKAAVLDNIESFAKRTSIRNLGPESKKLSTNDLGFLYDRFYTVLYERQQRAQYIQAETDRKARQAKLKATELATGVPGNAPEMGRIGLAGSATAMDYDAFREFLAGIAKWAITDSPSSPSKENASGPGGYFANTLRGMKNMNLSPWGAGPEPAEHEFLLRLFKKCDRDDNGFLTLQNVVYGLAPVKGNRDIMSSISYFFELYDDDDDGKVDREGILRISEALLFLSRRGVESGAAEVLQDGIPLSKDEQFLSAVSAFIRRCFEYADPDHSSRQGEKEITDGLDKVDISGEKEDDLLDLDGDKELKPTDDNPLGTDGAASSSAQDDSILSRPSTNTFGQSSKHVEANAALDPSSPVHITLPTFRMLILADETLESFFDSGFANSFHLADAPLPSSTLTSPSFLGLHSAPPGSGAPIPQLSEGSAMVGGSAAGVVAPGKGLRGMLDNIVTDGMRVAQEVKRRMDEAQKELDRGASTRGTGDDDEDDDGEDHGRDDLLDAAEADAGVTEKQSTDSTLKTDSGKGKEMDLLGEGITAEPKASASSAASVKSTDADVEKSTMFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LID0</accession>
    <name>A0A9Q8LID0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762403.1">
        <property type="nucleotide sequence ID" value="XM_047904667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LID0"/>
    <dbReference type="GeneID" id="71985397"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05519"/>
    <dbReference type="OMA" id="CNCTREN"/>
    <dbReference type="OrthoDB" id="3864028at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="28855" checksum="94E63E0EFBDB47B6" modified="2023-09-13" version="1">MLKRLRRSSKAEVQQRPEDASSAATVATQTKQINFFSLPAELRNDIYELAAHDSTLHLFNPSTAKSKLKPIPALLLASRQTRIEYLPILLSTASIKATVTDFNFKTLQSVLSSLYSTEQKALRSNNHLTIVLRFKKCSDDAYANLRRWTTDRASSLDKIAWRYRADQTAEPKVHRWYAERCRVLYGRVEAEGVKWEVRRVSEALEADLKPFMRTVVAMVAQGELEREQAGEGWVNGFGDDFIMMAATRRRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ40</accession>
    <name>A0A9Q8LJ40_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06671</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762791.1">
        <property type="nucleotide sequence ID" value="XM_047905819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ40"/>
    <dbReference type="GeneID" id="71986549"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06671"/>
    <dbReference type="OMA" id="YKLMGED"/>
    <dbReference type="OrthoDB" id="332281at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024602">
        <property type="entry name" value="COG_su2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06148">
        <property type="entry name" value="COG2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 2 N-terminal" evidence="11">
        <location>
            <begin position="44"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="32110" checksum="94BA7C820F25FF54" modified="2023-09-13" version="1">MSSFELPSASLSPASTPAAAPSPDRYSSDDDDLDTLPYPGELPRNDFLAPDFDPQTYLSTLRNRHQTLEDLRSDLRQRSQLLNKELLDLVNGNYEEFLILGSDLKGGEEKVEGVRVGLLGFKREVEGIREGVRERAMEVKGLVDERKEVRRDVVLGRSLLEVGERLEGLERSLGISEGEDEEDVEEFEDEDEEGGEDVVRLNIPLKKLQRHAMEYVLVTRMMDRIGASHPFLVAQASRMEEISKTILLDLAAALRQAKAAKSSEAILAITKIYGDLGAEDEGVKALKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3A5</accession>
    <name>A0A9Q8P3A5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755873.1">
        <property type="nucleotide sequence ID" value="XM_047900538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3A5"/>
    <dbReference type="GeneID" id="71981268"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01390"/>
    <dbReference type="OMA" id="RNIQAGH"/>
    <dbReference type="OrthoDB" id="2120038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034444">
        <property type="entry name" value="Nuo17.8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="22348" checksum="DFEA617D4D11FD33" modified="2023-09-13" version="1">MQPLQRTALRSARQVRSRLSRQRRRNVSDHGHGAHDAHAAPANESFGKGFYTTISAIPLSLALYKLSSQGTDEQPYFTRLITKTYAEYKTKWAQRNDFHTQAVEQAAADRVLFLTETNQSNVRHVDLRFPEQLNVGSPWNVPAGHGFANMDELIKKYETENFAENEKKLQQLRDNKVPVEQPFESFSKTTPAVDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3C3</accession>
    <name>A0A9Q8P3C3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">xanthine dehydrogenase</fullName>
            <ecNumber evidence="4">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CLAFUR5_01414</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="20">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="20">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="4"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756154.1">
        <property type="nucleotide sequence ID" value="XM_047900562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71981292"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01414"/>
    <dbReference type="OMA" id="PHPTQER"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014307">
        <property type="entry name" value="Xanthine_DH_ssu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02963">
        <property type="entry name" value="xanthine_xdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 20" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 20" id="KW-0408">Iron</keyword>
    <keyword evidence="12 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 20" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="22">
        <location>
            <begin position="29"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="23">
        <location>
            <begin position="260"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="1290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="792"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="823"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="827"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="905"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="937"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="939"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="1035"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="1104"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="UJO11788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1358" mass="148989" checksum="8AD1C3D1F5E79F82" modified="2023-09-13" version="1">MAPGLVDPQPAVEPSQQRNLSSVTEQYEDTLRFYLNGTKVVLDTADPEVTLLEYLRGIGLTGTKLGCAEGGCGACTVVVSQYNPTTKKIYHASVNACLAPLVSVDGKHVITVEGIGNVKRPHPAQERIAKGNGSQCGFCTPGIVMSLYALLRNTDGPSEHEVEESFDGNLCRCTGYRPILDAAQTFSSARGCGKSTSNGGGGCCMDDQTDGAKGCCQAGAKDDGQPIKRFTPPGFIEYNPDTELIFPPPLRRHEYKALAFGNKRKRWYRPVTLQQLLEIKSAYPSAKIIGGSTETQIEVKFKAMQYTVSVFVGDIPELRQCNFEDDYVEIGGNITLTDLEYLAVDAVAHYGERRGQPFSAINKQIRYFAGRQIRNVGTPAGNLATASPISDLNPVLLATNATIVARSLDETIEIPMTDFFKAYRVTALPPDAIIASIRIPVFNEKGEYMRAYKQSKRKDDDIAIVNAALRVHLDDDNVVRNCSLVYGGMAPTTVGAKKAMAFLEGKVFTDPKTLEGVMNALEQDFDLRFGVPGGMATYRKSLALGFFYKFYHEILAELNPEGTEIDQDCLAEIEREISKGRKDHAAGVAYEKKVIGKEQPHVAAMKQSTGEAQYTDDIPVQKNELYGCLVLSTKAHAKILGVDASPALDVPGVFEYVDHNDLPDPKANYWGAPNCDETFFAVDEVFTAGQPIGLVLATSAKQAEAGARAVRVDYEELPAIFTMEEAIEANSFFEHYHYINNGDVDRAFAGADHVFTGIARMGGQEHFYLETNAAVAIPKPEDGEMEIYSSTQNPSETQAYVAQVTGVAANKIVSKVKRLGGGFGGKETRSIQVAGICAIAAKKTRRPVRMMLSRDEDILTSGQRHPFLARWKVAVNKDGKLQALDCDIFNNGGWCQDLSAAVVDRALSHVDGVYKIPNVFVRGRVCKTNTVSNTAFRGFGGPQGMFICESFMEEVADRLEMPIEELREINMYKSGEKTHFNQELKDWYVPLMWNQLRQECDWERRTQEVAAFNAKSKWKKRGMALIPTKFGISFTALFLNQAGALVHIYHDGSILVAHGGTEMGQGLHTKMTMIAAEALGVSQDDVFISETATNTVANTSSTAASASSDLNGYAIWNACAQLNERLAPYREKLGKDATMKQLAHAAYFDRVNLSANGFYKTPDIGYVWGPNTGQMFFYFTQGVAAATVEIDTLTGDWTCLRADMKMDVGRSINPAIDYGQIEGAFIQGLGLFTMEESLWHRGSGQIFTKGPGAYKIPGFRDVPQEMNISLLKDVNWENLRTIQRSRGVGEPPLFLGSAVFFAIRDALKAARKQHGCEDVLSLVSPATVERIRVSCADPIIKRAHVEPQEGEKSFFISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3I5</accession>
    <name>A0A9Q8P3I5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756334.1">
        <property type="nucleotide sequence ID" value="XM_047901010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3I5"/>
    <dbReference type="GeneID" id="71981740"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01862"/>
    <dbReference type="OrthoDB" id="4152607at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="575" mass="65255" checksum="1DA6BB93BFAA73E1" modified="2023-09-13" version="1">MAAPTNGHDLNSEERGNEQQQIKAISTAQRKRKRSEEERKKKEKEEEKILLSQTEKEAIAAKTYAENEKDTFERQRQSVDNDWKARIDLSIGHADLVVGDTYESNELKATSLLKRDLTIAEYEYRFVRLDGESEAEVKRRVKAYRDKTNFDFDLSDDDDYLPKVVDPALLSKIRGKFQGGSIAYHHGKFVVIHIIDTTEVRRFDDPKVPVEFFLAQDLLREFDIQGWSGWNAGLERPKLRKPYYTHEWITHHAVYVPQASETSAYEAKLEDLIDGGLYELIPELRTTEEDDMKGLYHRCVYTRSLTHRKIKPCVKPITQDDLDLATRLAERFKWKHRVGKESRVRHLDSGRKPALVTPHVNIILDLLGIHERPEQNPVLRNWAMSGVGGFTFCPAGFRGLTRVPNNIPEQMQTVELAREVCQALHAGPLPQTKVWLADSRFNWRGKWLWTDAFCIKIRQKDPKKKRKSTDSKKKGKDQPPDQNDASDANDTANDGSTMTNDSNASTDQSPSSDDTLPRKRQKTGSASESFANAADPAADTVIDRQAEGDADETSPVKAAGDVAVEAVAQQLLAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3L1</accession>
    <name>A0A9Q8P3L1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756173.1">
        <property type="nucleotide sequence ID" value="XM_047900489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3L1"/>
    <dbReference type="GeneID" id="71981219"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01341"/>
    <dbReference type="OrthoDB" id="3650417at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="92"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="282"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="454" mass="51147" checksum="2E16447C9B2B0B8E" modified="2023-09-13" version="1">MFHDSLTDPTRFPPRCCTLIQLYTVLPWFHPEGTNTFRLKFEEWLAIDKLYCPSPACSAFISEKYKVPSNEPIVEPAPSKQQVMKAIFHKLDTSAEARFFRTDVHTIELPGYTKRVPKPIHLQRIQQKIDDHEYTSSAEMSQDVLLLHANTKRYNGHQHPVSLAADKLLSKYLEVLSSTADQLSAVRRTVQHDIFACPTCHIAICTSCKHIEHRDKGACDTSTNDEEVAMLQQFGYKKCPRCKHGVRRMYGCSHMQCTCGAHWCWWCLRSIDECQGDCAGPADDEIDDEDDEDSEEGESDSDDGVVSNNGDTPMLDAGPPAPINDPTRVLASPIIQAVNLDAGGSRRWAGGGYDFGDEPEDPSVQVWSCEHSWIEFRTPTDRFDHGDLNYLECNRCFESLQPAPPLMPTPSRPGTKDRPSKQPDIGKEAWDCMRCRLIVCTGCRDKYKSSARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P480</accession>
    <name>A0A9Q8P480_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar import and degradation protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756833.1">
        <property type="nucleotide sequence ID" value="XM_047899697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P480"/>
    <dbReference type="GeneID" id="71980427"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00549"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
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    </evidence>
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</entry>
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    </dbReference>
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    <keyword evidence="7" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="37"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="39087" checksum="9C02E1C87530DDA5" modified="2023-09-13" version="1">MVLLDQIQATGPVKILGTAAPCATALFALECFTAKKHITPLSVNFHFTRRCNKTCVFCFHTEKTSYLASDEDMKKGLTLLKEAGMKKINFAGGEPFLYPSKLAMLCRLCKEDLKLESVSIISNGTKITEKWLKENAQYIDVLGVSCDSMDEETNIKIGRGTGENVQMLFRIRQWCRNLGIKFKLNTVVLSHNWEEDMAETIRALDPFRWKVFQVLPVEGENDAKEEETLLDKRKRNANSVLITDEQFAAFCDRHKHLSCFVPESNDLMASSYLIVDEFLRFLDKGNGVEKASASILDVGVQKALAQVEWNQEAYHKRGAVYEWSKDIEDAGEEGCGAELPEEYQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8G1</accession>
    <name>A0A9Q8P8G1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C6 finger domain transcription factor adaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761212.1">
        <property type="nucleotide sequence ID" value="XM_047903183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8G1"/>
    <dbReference type="GeneID" id="71983913"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04035"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
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        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="697" mass="77309" checksum="AF37669E3DCA901F" modified="2023-09-13" version="1">MDNQRDSSSPGVPNHSRRQSTGLHLACRECQRKNIKCDRTYPCGQCTRSGLRCQSSTRKPRAKAGAKAVDADLRNRIAKLERLVESFQGDESSSDAPSITPATNATKSRHTSMTGPESLAVRQNSDSPSSPMDTALPYTNKYVAGTFWSSLTSEVKALADAFEEDGLPSDDETTSPETTPPSAPYALDSTNGASAGYELILCPPGVLYVMPGALQEPAPERSAELIHNFLEYVEPSYKMFHVPTLAAFLQQGQPYLHRAPDAPCNKALRASVYFAGINAHTEEECQETYGKPLNQMVQEFRRNVDVALYQADPMNTTETATLQALVLYVASVRVMDPSRRAWSLIGLLVRIARAMGIHREIAGESPFLAEIRRRLWYNIVFLDCYASVDRGSEPAIHPETFSRLLPMNVNDADFGEYSLSVNNTAGRHHRHLPLKFSLPEDSTAGPAQSWQTRLELAYEYQRSVNDKFIRHCDPTNMKHHMMIIGTGTAATNAMILRAVRPIQIHPNSVPPRVDSPWVMELALNILRHANASWEQTVGRWRRMPWVPWHAIGVALAGLCSIRGTDQANEACVLVEQAMSRYGANVADSPTGMLWRPIEKLYKKAKAFRDQSDVLVPVSAPAPIPAKVDPGWEAPIPQQPLTMQSSPAAPMNPLGMPADVFNFPPDMQASLPSDNSWLDWESILKDMDDIKADDMQWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8M4</accession>
    <name>A0A9Q8P8M4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761751.1">
        <property type="nucleotide sequence ID" value="XM_047905032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8M4"/>
    <dbReference type="GeneID" id="71985762"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05884"/>
    <dbReference type="OrthoDB" id="5367052at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1266" mass="138130" checksum="8C453F3A1B76F014" modified="2023-09-13" version="1">MSQQYDCPLPPPPPSPRSGGTSTRAGSVSGSVAPQADARSVSENLHVHRTRPVSAVLPSITTTCLSPQGVYSSQASTPVSGNRLSPGIFPYAPGTPSGLNPQTPGGLVPPPPPPATPRSPNMEPYNPLQWSRGQVSGSQMVFQQRHSTMPPSTMQLIGQEAAMPSPPPPYSPATPDHAARAATTSASTMLDNNGFTASPMAESSSRSSPQIPMSPAFPPPPGQSSRYRERSTSGLGGNKSFFSLSGRRGKQPVNLEPYVPQASSSVHTPSWEDARPPAARRAASTGHIQSGSSAATSSAAVSTRASPEPNWHPGMPLPGPPPGPPPPGARSQSLNRPLGAVASSSSGIDRRVGVSQQRRTLAAVAPSLGPVPPTPANWIDSDTPAQEPAQDVIEIRPPAGSASQTEATSPPLRIHTGASRDNSLARRPARRDTSMQGLRERRSQSRAAQGTTEEDTRRMSNLVIAPPESGSISRRREHMRNISGYAEPTSAPSPLSKEVQQEAKVPGNILTPPYTPAPGKQPLHSGKQIKMPGSASSDRPISHLLHTPNEANSTITAPLSPARPQSSGSAKVSTKLDAFAVQAIERHKAFIEKEAVATTDEERLELFANFMVHESRLRRDKYTVAYNAMAGDIVDLTRDMWRSYGGSKRSITPNTALSSIDPTVPSWASDGQPTSAHTNMPSSASSMGEFTPATDTSSIGDFGFERTETRQWADSFKPSLSPIPSMAVSTVPDEDSSRGRTASRWWEGSNSQGGSIGRPDRIEKTRRETKYMGINPAELHALTPEPARHSPAPEADAPAYGYGPDEYPPEKTGWHEEADYDTPMVTPNRHGDRKTSTPGVEPLDVSRLVTLPPPYPRHHPAVNNSHPLLSDLRNEHRILADATDVQKIKDAYMDQDFALTGQQKEAEKRRRVKLRLSIQNKISEGSISFADAARAEADFDGEEAERGKANARANFDVFEASVAHPLNTLLTERLTKANDCIKKLRAELESGHNSADPNRAQEEGDEHPERLEKLTLLKWIFEAREQLNKEMFDLHTMRSEKYSEVILTPFRISKDTKKMGEATTFFKKDSIERQITYARESLRRFEELQSVMEKNVSQGVEDQLSAFWDIAPGLLEVLQQIPAQMSCLDVQIPLQEYEENPSYHQHPLQYLHSLLNHAEKSAYQFIESQTNLLCLLHEVRTATTNSRLRLVEIERNASNGDEQEIRAEMALARREAEDHLTEDLKEKVGEVDRQWKEALGYGIAECKERVSVWLEESGGLEEGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8Z8</accession>
    <name>A0A9Q8P8Z8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
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            </authorList>
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    </evidence>
    <sequence length="399" mass="45547" checksum="AF1F7CAA17C5466E" modified="2023-09-13" version="1">MMLDGGNERKRSMLTSICVRGLERISPTFAQDNNPREVWQGGRLYHEDIEREDEDADEDDDDDPEAMETLSPTLLKAAIALHDMNIFAKAAENVHEKSEDNISIMIAALEQFFTVPAQSQAEVHRWLDAAWPLGNVEDELLPLYKSMKEASGIPAERTQSWFDSKLDEMVAIGMLAAFAKGAIVIHRDKLIRLHITDAMLKSPYYGFDERALDFLSAVWGLHRAKMLSIEETRRLFEATIQRLAPHESGKLQKNFPNWPISGRLGLVACGKSFAKLIIRLSELKLDDPLENLLACMLEAYRGCSRRDKLSSIQPVLNTFSKSYTDQQIDARLRDFLCSLVTTCREDYIGTPPPLTSKLWRRVVRCKLPDCDDCPKLNKFLGDVDQRKFEVLLNKERHHR</sequence>
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            <authorList>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO18075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="154" mass="17619" checksum="07654D4F0F13898A" modified="2023-09-13" version="1">MNIVQELQRHPLDDRAEKMWQNMSDNYQARRTRLHQANFLFLKYLGKTILQAWEATEAAMKQKGMALEEPQIVLDIKHNLGEVQDDSNLGQREPSGIANHTLQDNTEARLPDVSAVPYFTNSLGMESVGYREMFETTMSGFGTDWMDCATIFGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAA2</accession>
    <name>A0A9Q8PAA2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cysteine proteinases"/>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
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    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MATH" evidence="7">
        <location>
            <begin position="141"/>
            <end position="298"/>
        </location>
    </feature>
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        <location>
            <begin position="764"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="542"/>
            <end position="564"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="816" mass="92354" checksum="BD41BE99786216A9" modified="2023-09-13" version="1">MEAEEAVPPPPAAIPPPPASDRPDIPPFDPPIRYPDGWDAPRGFYRYPQPPVPAIDEHHSDSNEDHEGESDHEDEESDEDDEVPPHMRWHEIHEDTSEPSPDEQQWIADHADRYPSALDHEHWAQQAFLDLKDPEFETIDTGRIEWHVEAFNGTKEKPNTEKIMRSQIVRIAGLDWQIKFYPRGNRDSDNLCVYIDCVSMRAPEWEDLEELDNPPFPVLEGADKIKVRRSVAAQIAVVMYNPAEPRANEFKIEAHNYHKKNPDFGWPYFTHQRELQVRRQSWPQAILRNDKLSFTAYIRVVRDPTRCLWEHDDRSPGSSTSLIGLRPFTRSFPYIAATIPLLHYGPFRKLVQQLSSNTSLSRWLQTVLLKMYSRSQKLPCESRGRSRSQDDKDVAEVLWKIARTMNEQHPGHYDAFTQLIGSCDPQGGAAIGPGRLNTKDYPSIQAAINKHHEATPLAQPELLILELQRQEHDKKERKWKKIANSVDVEERVTVGGVSYQLYAFVTHQGPLHSPRYSTYLRPDGTQGGWYAYQKDKVFKVTEKQAKDKRSGPITTGHDSPHSGYQDATAEVTQLVIYVQDEAVPKLMAPTHVETWAKPLETTPDANTDSLEVRLQKATSFSTPEPGLTDGEDVIMKDADQDSEYGSDDNDPAAIGGIVDWLGRPYYEGQWQGKKYHGGGNLIDLNGDEYLGSFNHGLKHGFGQMTYSTSGNVYNGEWEDDLPHGQGTLTEKSSGNIYTGGFKHGKKHGKFTLTGTVTEEDQSCCSICYEEEIDIAFDRCGHAIACHECASQIDVCPICRKAIQSRIRLVGVKVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC0</accession>
    <name>A0A9Q8PAC0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763168.1">
        <property type="nucleotide sequence ID" value="XM_047906764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAC0"/>
    <dbReference type="GeneID" id="71987494"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07616"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="23991" checksum="FDAFAAAF5A188394" modified="2023-09-13" version="1">MLPMIQTPTQLTHLHLASLHINSDPKAITLNDNNPNDTIWNNVWNETAQLQAKGVKVLMAIGGAAAGSYPRLCSGRNGAINETYYMPLYYTLKYHKLTASTLTSKNASQLQASGYGLGGFSYKTLDRYATSSLRPNGKLVNWYQPQFYNGWGDASTPNGYMSIVKNGWAASRVSPGVLDDPNDGGSGWFNLTRYQSTIKSPDTIGPVGVPGIHLFSRLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAG1</accession>
    <name>A0A9Q8PAG1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prostatic acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07654</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763250.1">
        <property type="nucleotide sequence ID" value="XM_047906802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAG1"/>
    <dbReference type="GeneID" id="71987532"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07654"/>
    <dbReference type="OMA" id="YIFHRHG"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040275793" evidence="3">
        <location>
            <begin position="19"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="483" mass="51283" checksum="1CC95E0F78300E07" modified="2023-09-13" version="1">MLTSAAIALTAVAPLVAGQNTETVLGVYMFHRHGDRTAKSTPPANLTDLGYSQVYTSGQYYRNRYIASNASLQINGINSDIVKQSQIAVSAPDDTVLQNSAMGFLQGLYPPVGESLGTATLRDGTNVTAPMNGYQLIPVDQVSHGTGSEDSGWLQSTSNCAKASISSNEYFSSAEYLNDLDHTRDFYQSLLPVVNATFDESEDTFKNAYTIYDLINVATIHNRTIPSSDLLTPDTLRQLRTLADTHEWNLAFNASDNMRAIAGKTLAAQVVQFLNGTITGQGKQKIGVQFGAYATCASFFGLVDLPAADKDFYGVADYASAMTFELFTNSSTAVSATSYPTAEEMYVRFLFHNGTTNSSSEPTAYPLFGTQQETISWKDFANEMGKFAIGDTKDWCNACGNFTGTCAAYAPDSASTSQTGEGGSGSGNGLSPVVNGVIGAMVTLAVVLGLEALVLALGGLRVVRKTRARSPVGSMVESGAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB72</accession>
    <name>A0A9Q8PB72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763596.1">
        <property type="nucleotide sequence ID" value="XM_047906059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB72"/>
    <dbReference type="GeneID" id="71986789"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06911"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="93" mass="10317" checksum="86C9447EACE31A4F" modified="2023-09-13" version="1">MIFIYDDLEIHASVECEAGKLGNAEYCDGATRVRGVHVNELDCLEAFARVVSKCNRPGAKIERGGIEADKCLVWRMDMAKLGGKHQAARHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBA2</accession>
    <name>A0A9Q8PBA2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763641.1">
        <property type="nucleotide sequence ID" value="XM_047906178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBA2"/>
    <dbReference type="GeneID" id="71986908"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07030"/>
    <dbReference type="OMA" id="INGGPFN"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="49618" checksum="3DEB07CDDD6626F0" modified="2023-09-13" version="1">MGFPIPADKIETRHYINGEFAASSDKATFELKSPYSHEKIADISEASVDDTNRAVAAAKAAFPAWAAKSPAERGALMKALAGKMRPLHDELAQLNAMDMGRPVSTYFDGYYAASLFEHYAEAGYEAKGTTSLNTPGFVNMTFRQPIGPVAAIIPWNIPTLSFAMKIAPALGAGCTIVLKTSEKAPLTPARLAHAVHECGFPPGVINILSGHGTPSGATLASHMDIRMVNFTGSTFTGRKIQAAAASSNLKKVVLELGGKSPALVFEDADLKKAAADTAGSMHMLMGQACVANSRVYVQESVAEKFKEAFIANFASPKKGDPLDPETQQGPQADGLQHERIKSYLQAASEGKGKLETGGKATQHDGKGYFIEPTMYSNVDENEKTQKEEVFGPFVNINTFKTEAEALEKANATEYGLYFSVYTKDINRAMRVAKAAESGTVAVNCTSPSMAMDTPFGGYKGSGQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBS0</accession>
    <name>A0A9Q8PBS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763909.1">
        <property type="nucleotide sequence ID" value="XM_047906328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBS0"/>
    <dbReference type="GeneID" id="71987058"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07180"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="12933" checksum="C63CDDDF79053207" modified="2023-09-13" version="1">MVSQCSDISLDLSTVPDTNHLEAPTVEIEAASVCATLNNAPGNSNSDLLVEPEWMRMSAYSYATGDKVTISWIWLHGWRLEDKNGKECWLCKRCHTASEKRRASIAPIEAQAPLVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBU1</accession>
    <name>A0A9Q8PBU1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Retrotransposon-derived protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10633</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBU1"/>
    <dbReference type="OrthoDB" id="5088132at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032549">
        <property type="entry name" value="DUF4939"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16297">
        <property type="entry name" value="DUF4939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="572"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="617" mass="67591" checksum="9D689EF82441B13D" modified="2023-09-13" version="1">MPGPPDEVEVDEPVNLPSDDYAVRKIRGIRVEPNDVEGLPPIKYEVEWQGCPEWDTSWEPIQHIIFNRQAIEEYHARADGPEVNIGRLFESELFDGAYQWCIDHDIRPRPGTQLCSGGATVMVSPQSVQKVGTEEPQSAQKSSRSDSPAWCVSAKNHMPRNIRYGTQPSKFTPLPNLDRFTSARDCVTHGTPGSTRDCAGPWKKHVEDSERQALALTSQKTNKPSTTRVILMGDHATDRGVNLDNQDTPFHFSEWTDIPFSNAAAFGAWANANPDTAYALINRTVSSFRETAQQVEQANNQATYLQGIVNTFQNLAPHADDNRRQHFSKKVNDPDEFDGNKSKFEAFETQLTIKLLANADHFPQEKDKVTYVFSLLRGDAAAQVQHYIDNATQTIGCPDVLALMQDLRAAFGDPDRRATAQNAIHNLLQKNKSFAEYLAAFNRDIGFTGYNEETKKSTLRRGLSAELLRALEDKDVGAMSFRELVETCQRLDSNMKHTASLLASRSQGRQPRGPGSHFAAPLGAAAPTALPPVSVGDAMDLSAGAAVPRVQGLVNGKLTPEEKLRRRQAGLCTSCGGPGHIAANCPQLAARNARNPVRGAVGAIEPAPAAPAEQGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBV8</accession>
    <name>A0A9Q8PBV8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763993.1">
        <property type="nucleotide sequence ID" value="XM_047909504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBV8"/>
    <dbReference type="GeneID" id="71990234"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10356"/>
    <dbReference type="OMA" id="GLWFFNS"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="1">
        <location>
            <begin position="183"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="32176" checksum="ACB14467794D885C" modified="2023-09-13" version="1">MEATPLERRALQSFDDLLTREEVFWKDTPPHLVKGSPFDFEFRVAPSFKSKPILAADAKGRSEDTDAFGDDDPAFTVSTIGSHHKLILNKFCVVRPQFVLHTKDFEKQSDPLTYSDVNALRQTMQELGPGKYIGIFNCGAKAGSSIGHKHMQVFPTSDHVLFQDHLVSQHRADDSSTEIWRHPKVPYEHAILPITHSTSPDAIHKLYLELRQNMRLDQDYPHNVIMTSTSIAIIPRTQARIRCMAANAASMVGMVWVKTEDELNAWKEYGPMKVLAEVGLPRSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCC3</accession>
    <name>A0A9Q8PCC3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764224.1">
        <property type="nucleotide sequence ID" value="XM_047909048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCC3"/>
    <dbReference type="GeneID" id="71989778"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09900"/>
    <dbReference type="OrthoDB" id="10593885at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="22203" checksum="0C73365CFAE9FA79" modified="2023-09-13" version="1">MVQQKFQSSSSKGHAFAWKTTPGTLPVLPSIKQKSTAKSSSCPELTLQAVKCSLDVFNSIMAGSKTIAGTIESNAEPPESGDEGIDAAPGSGNGSRPANQPTKGGKTSRPASGTMKPPGKNTSTTSGKGPRIKYVPEGRKSTRVLARGSHYRILELKKMLESVRNLARVEEDPALDHLLDLLREAYSAMHEIAPDPLSPDNPQSPWSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV9</accession>
    <name>A0A9Q8PDV9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765072.1">
        <property type="nucleotide sequence ID" value="XM_047910749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV9"/>
    <dbReference type="GeneID" id="71991479"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11601"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="108" mass="11851" checksum="DCB1E1EEA540BB0F" modified="2023-09-13" version="1">MKDIRTTLKNLLANLKAKLKIGSKNKKRGDQVMAEAAGDPHANYTPQDRLRGLPYEATTSGKPPCIDEEPEPSPATSVEEQRKLKKGADARVPTDLTGVAEELDRKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK4</accession>
    <name>A0A9Q8PEK4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydratase CTB10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765396.1">
        <property type="nucleotide sequence ID" value="XM_047910552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK4"/>
    <dbReference type="GeneID" id="71991282"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11404"/>
    <dbReference type="OrthoDB" id="3183782at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="116"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="19526" checksum="ECF6364E011E0009" modified="2023-09-13" version="1">MTKTNQGRLLAYNIYITRKASMDQESHHRHLTEVNTPIIKPLLEKYGAVSYSVVSIKALETLGCPQADDWTRFIMTQQSIVTWMSCLVGGTQSSNEFSADCVVIAGMPVEKRPDVLLPYDTVVSIVVPNVDCINRMRSDPDFLSKYMPDHDNFADLSRSRTSLGWVEAFSFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEN8</accession>
    <name>A0A9Q8PEN8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765388.1">
        <property type="nucleotide sequence ID" value="XM_047910671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEN8"/>
    <dbReference type="GeneID" id="71991401"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11523"/>
    <dbReference type="OMA" id="RIHYGAY"/>
    <dbReference type="OrthoDB" id="5313288at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="29492" checksum="99B96AC0DF55800D" modified="2023-09-13" version="1">MASTSNREKGSERITKLPSELLHIIFNCLFVRHYPNKVLGGRTEAHDTPRGYANTEHAHPLDFVAATCRTLRSETNDWAIHFLVQHKDITRFTALPRKKKDHTFNMLRGRTGLLSWAERHCIFCGRNSSRSAILINGLRSCAACDKVQWPDKITKTDAREKFDLKDEHLLPQRPHGSALAVKLEAQFPNGLPRIHYGAYIQQGGTTVMFLKKDVEKLARLHHGDLEAHLAKREARRTELRRKKIDRDNVKRVPIVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEZ8</accession>
    <name>A0A9Q8PEZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765639.1">
        <property type="nucleotide sequence ID" value="XM_047910121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEZ8"/>
    <dbReference type="GeneID" id="71990851"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10973"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="24725" checksum="7BD0A30C10B76BF5" modified="2023-09-13" version="1">MTPSWDTFANELQNDLFVRITVSEVGLNDTVYRVSYLTLKHAAPELAKQVVDLDRYQYAFSGKELKLDYPKSPEVHIALYYIIHKELPSDLLSERDHEEIAIKCWCFGHQFKMAHFQNAVMRKVLLYLQSSNLSLDAIATAFKTLQQGSVMRRLLAEELVVGIRDRERSYGELKQFEGIGGFLTEFVKAMDEYDDDEIDTDKRLDDDRVGAYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF24</accession>
    <name>A0A9Q8PF24_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sterigmatocystin biosynthesis peroxidase stcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10928</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
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        <text evidence="7">Belongs to the chloroperoxidase family.</text>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <dbReference type="ARBA" id="ARBA00025795"/>
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        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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            <end position="29"/>
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            <dbReference type="Pfam" id="PF24800"/>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    <sequence length="275" mass="29650" checksum="7A5261CA5AF7354E" modified="2023-09-13" version="1">MHHLTSRGDLSIAELIFFSPSLLAALFICTKQGFPPSSGWLYLVLLSILRLIGASVTLYMESNNDYSPSLVETVAITSSIGRAPLLLVLLGLLERIYAAVAGGAFNKSVFRPIHLVGLVALISAIVGGSMESRDKGSEQDTGKALRQAGSVLFLVIYFALAGLTGLTALRRAYIASTDRKLIIAGCAVLPFLLVRMIYTVVVSFAHPGSHFYYLAPSARVTAFMMFLMEAICIVLYSWAGLITPKAVTPPSQTGRKDLESNGVDLSRHSQGRVRP</sequence>
</entry>
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            <authorList>
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        <source>
            <dbReference type="EMBL" id="UJO21605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="84" mass="8985" checksum="C469337620D58DDF" modified="2023-09-13" version="1">MFPTTTSDIASIATSAAIIFGMYKLDRGAQRQRGLMEGPGDLQDQQIDEFMKRCGKLSALCTFATAGNGAFLYNMGGGALSWVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG27</accession>
    <name>A0A9Q8PG27_PASFU</name>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17248" checksum="7BE9C33F86CBC671" modified="2023-09-13" version="1">MANAVATTKTTGAAPCLVKEFFETTSSSSIKPTQALACGTAANPKKIFDLCVLWRAPAPRMVGRNLRGVACALNVGMLEGARPDHAIYFDPKSKKHRQIAIPEGRVHSVASLIQNQEWEILEHEQGFHWETPPRTGPAALREPGETQYEYVPLPELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGD9</accession>
    <name>A0A9Q8PGD9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766490.1">
        <property type="nucleotide sequence ID" value="XM_047908238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGD9"/>
    <dbReference type="GeneID" id="71988968"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09090"/>
    <dbReference type="OrthoDB" id="3650508at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="63"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="18511" checksum="BF53C46FF1B92B88" modified="2023-09-13" version="1">MTMAQSDITTRIRDHVAFRLRREHPYMKTATLEKLLDSLTSNLRDSLQYQAQELQDTKARANFFMLPPELRNRIYELVLVASPPLIIKLPKYSRLTKIYRWRTIDQPYGQIPIEILRVSRQVRQEALPIFLGANTFELTVLWSNPVDMPNQLELRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGS6</accession>
    <name>A0A9Q8PGS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deoxycytidylate deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09097</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766493.1">
        <property type="nucleotide sequence ID" value="XM_047908245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGS6"/>
    <dbReference type="GeneID" id="71988975"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09097"/>
    <dbReference type="OMA" id="YFMRLAD"/>
    <dbReference type="OrthoDB" id="6710946at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000035">
        <property type="entry name" value="dCMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002333">
        <property type="entry name" value="Deoxycytidylate deaminase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="186"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="39025" checksum="9BC00CEFBFA0C99E" modified="2023-09-13" version="1">MLIGICGGICAGKHSVLQYLIQNHNFQLLSLHRNAATPSVEKSASEAHVPETTYGDLETKFNTVEDLLEYATKHWQTNFATVSLYDEHIAEVLSRRPFFILLHIDAPISLRWTRFKDRCAKAALTPPTLDQFVLRNDAHLYSPSTGLATTATRAQIKLLNSTTSLNHLWTSLDSLNLTDPSRLRPTWDHYFMTLASLAARRSNCMRRQVGCVLVREKRVMATGYNGTPRNVSNCNEGGCPRCNGGGIGGVSLSTCLCIHAEENALLEAGRERIGDSAVLYCNTCPCLTCTIKIVQVGITEVVYSNSYYMDDEAAKIFQEAGVKLRQFSPPKEGLVNLMIEEVPLLNGHSDTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGW2</accession>
    <name>A0A9Q8PGW2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766543.1">
        <property type="nucleotide sequence ID" value="XM_047908020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGW2"/>
    <dbReference type="GeneID" id="71988750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08872"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22517" checksum="4DE5BD0DCAB24890" modified="2023-09-13" version="1">MTTTISATTIINGTSSAQPSLTPVPSAVSSSPIPIGYVVVGTVYISILALLFCAVTVFWVGMKIVLAIDRYKAHKVRKAEDIENRVVTETVRRRMPGRLIRRLRRRSERSYARKVVVEIEMQPVQSDSGPDHDDGRQRSLYPMRALHTEKRPHLTHPDRNSTCDSQHSIHDNSHFVELVEVPVDVTVDIAAWWQSGYSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH09</accession>
    <name>A0A9Q8PH09_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766674.1">
        <property type="nucleotide sequence ID" value="XM_047908355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH09"/>
    <dbReference type="GeneID" id="71989085"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09207"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="28157" checksum="6C7C256E216E942B" modified="2023-09-13" version="1">MDASSEDAAQVTALFSYVASVPEDEKAYHMMYGDCEGIPTTNIERQWVNTIFTDLRGRETALSYDKAGFVVHRMHSKMSYGDFDDEKLIRNVYFKELEDHVRGWLGAEHVKFFRFGIRKRHAQFPTSTGKEYDFAQPTTIAHVDATSASTVEEMTRQFGHDAEEFMARRYQWINVWKPLRGPVNDWPLCLCDASTVQQSSCDTTDMVYPEYFTENISLRHNEQQRWYFLSDHRADEIIIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH24</accession>
    <name>A0A9Q8PH24_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U3 small nucleolar ribonucleoprotein protein IMP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">U3 small nucleolar ribonucleoprotein protein imp3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09463</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766648.1">
        <property type="nucleotide sequence ID" value="XM_047908611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH24"/>
    <dbReference type="GeneID" id="71989341"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09463"/>
    <dbReference type="OMA" id="FRIKHEQ"/>
    <dbReference type="OrthoDB" id="10248812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000006">
        <property type="entry name" value="U3 small nucleolar ribonucleoprotein IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="11">
        <location>
            <begin position="112"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO22282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="186" mass="21390" checksum="25BF7E2F24BF9E1F" modified="2023-09-13" version="1">MVRKLKHHEQKLLRKVDFVNYPGDDQHRSAAVLRRYSISNPSDYSAYNRLAGKLRHLAHRIALLPPESPFRRSQEGKLLDKLHDMGLLGHGDTGGKLSDVEKKITVSAFCRRRLGVVMTRLRMAETVSAANRFIEQGHVRVGTEVVTDSAFLVTRNMEDFVTWVDSSKIKRNIMKYRDKLDDFDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHA0</accession>
    <name>A0A9Q8PHA0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766768.1">
        <property type="nucleotide sequence ID" value="XM_047908302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHA0"/>
    <dbReference type="GeneID" id="71989032"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09154"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040348667" evidence="1">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="67" mass="7090" checksum="8B95846C0F124AE4" modified="2023-09-13" version="1">MKFSLFAIPALSLLASAAPTASNNAVEQRAAASPLEQWITGLTTEVKGYTAHLSPSQHVPNIMVLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHE9</accession>
    <name>A0A9Q8PHE9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_12205</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766926.1">
        <property type="nucleotide sequence ID" value="XM_047911353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHE9"/>
    <dbReference type="GeneID" id="71992083"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12205"/>
    <dbReference type="OrthoDB" id="2574at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13592">
        <property type="entry name" value="PBP2_HisGL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.120:FF:000003">
        <property type="entry name" value="ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000123">
        <property type="entry name" value="HIS1p ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="59"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="241"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO22560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="33934" checksum="EAB95F4B90DB9B3E" modified="2023-09-13" version="1">MDLVNHLNDRLLFAVPKKGRLNQACLDLLTGSDIKFHRHNRLDIALVKNLPLALIFLPAADIPTFVGEGRVDLGITGRDVIAEHEAVSPASETTGIEEIMDLEFGQCKLQVQVPEHGSIQTPEQLIGKNVVTSFTNLAGSYFGGLEAKATGQTNGVTNGDAKPKLQTHIKFVGGSVEAACALGVADGIVDLVESGETMRAAGLKAIATVVDSTAVLIKSKHPSDPKLVNLITARIRGVITAQKYVLTTYNIERRNLEAAKRITPGKRAPTINTLDEEGWVAVQAMVKRSDSAIVMDQLTEIGAVDILQTALSNSRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIL3</accession>
    <name>A0A9Q8PIL3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIL3"/>
    <dbReference type="GeneID" id="71992020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12142"/>
    <dbReference type="OrthoDB" id="5272396at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF24864">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="123"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="34476" checksum="6190BDEDA58C4B03" modified="2023-09-13" version="1">MVPEDSQALAASLEQLSLQDRPRSTSPSANQPSTEGRARITRDARSSASTLKASASPNAYDAQQNPGSPSASNASTAPSNEPVQFSALQRHYLTIGASGVNGAARQAVTTQPPIRTSRTCILPEVLPGEMRNGIYEEALTISPGTDGTVELVKWGQVRTSSSSTLRRWDSAAGREVRKQPVAALLATCKQVFNEACSIYYYQNHFKISGDDKGLNTASLGHFMLSMRPARSRHLKSLTITVNDFEQTVLAMNTMQQLMGLEELCIIVEADGPVDRFEENKEAFAKAFGEMLGLKTFSIQSSSIDEGMEWVADALGIELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIT2</accession>
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    <organism evidence="1 2">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767572.1">
        <property type="nucleotide sequence ID" value="XM_047911075.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71991805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11927"/>
    <dbReference type="OMA" id="ADYNSVH"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034595">
        <property type="entry name" value="NDUFAF8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="60" mass="6532" checksum="5CFB444E0C140BC8" modified="2023-09-13" version="1">MPGRTRPIEKFAEAAAKCSPEGAVYGKCVAASYQNVKKDMCAREFMALKDCYLKAAGRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ51</accession>
    <name>A0A9Q8PJ51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767726.1">
        <property type="nucleotide sequence ID" value="XM_047912448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ51"/>
    <dbReference type="GeneID" id="71993178"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13300"/>
    <dbReference type="OrthoDB" id="3655236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="156" mass="18460" checksum="B5242E078D8C29A9" modified="2023-09-13" version="1">MSKQSRQEKWQETLALRARRWLETTGPIPYSLTITVPAWHPVYENPLNLEYPLHFDDSATLRPITKEEGRDGYADWLNLETDFITTFPWTCDFCLEIKYTRAKFRSDPPMPVSPPFFVVVVYKGADLASVHERIVELIRKWMKVEDPVVRYFDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ53</accession>
    <name>A0A9Q8PJ53_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc-binding alcohol dehydrogenase domain-containing protein cipB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767738.1">
        <property type="nucleotide sequence ID" value="XM_047911805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ53"/>
    <dbReference type="GeneID" id="71992535"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12657"/>
    <dbReference type="OMA" id="WIKYPFI"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="24"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="37651" checksum="496C4EC13D047C58" modified="2023-09-13" version="1">MKSTGFFTSSPKNVAAWALKSKERPLTVSSAPYTKPPKGHVVIKVYDVAVNPIDWILQEDDIFKSKYPTVFGSDAAGEISEVADDVKDFQIGTRVIAHCSRAPDSDLPSGATGAFQKYVVVQASAVAELPYKIPSSTGVVLPLGISTASAGLYQKDFLNLPYPVTDDKPKPLNRTLLVWGGSSSVGSCALQLAVASGVEVVTTCSENNFDYVKGLGAAAAFDYRGKDVEDQVVKWLDGKTVVGAYHAVGEGGAQAAARIVDRSKGKAIVVTVRGVPEKGVPSSVRMKAIGATAIFSNEVGPKIWREFLPKALKNGTIVPKPDPKIVGENLRSVQLGLDTQKKGVSAEKVVVSYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJT4</accession>
    <name>A0A9Q8PJT4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJT4"/>
    <dbReference type="OrthoDB" id="3935025at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33481">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="15026" checksum="1E7D388FBA94DDB7" modified="2023-09-13" version="1">MAQGHCPKHFKESLTVVLRKPQKEDYTKLKAYRPIALLNTLGKLLEKIIAERLTNLAEEHGILPEEQMGGRKQRVTLTAVELITEQIKTLWHFGNNKAATLLLLDISGAFDNVSHQRLIHILKQKAIPNWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK49</accession>
    <name>A0A9Q8PK49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768372.1">
        <property type="nucleotide sequence ID" value="XM_047911778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK49"/>
    <dbReference type="GeneID" id="71992508"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12630"/>
    <dbReference type="OMA" id="VHMTSTI"/>
    <dbReference type="OrthoDB" id="10654953at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040511099" evidence="3">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="21243" checksum="2F37FA4120C18066" modified="2023-09-13" version="1">MQNKLITLTAAAAMAGMATAAGNSYKVVYETTTSTKSICPDHAATALSEPITTSTIVYTVTVPAGDCGPTSSASNPVVTETTTITTSREASASSKFSSNEVGPTTGDVIGASSSQLDSTVHMTSTINAASTVTIGADSTTETKAPVATPYAPFPPYSAPGNSSSIIGTGTGTGAIPSGTGAFPLPSGVETFPGGAAAIGMSSILALGAMAAGALFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKE8</accession>
    <name>A0A9Q8PKE8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13837</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768507.1">
        <property type="nucleotide sequence ID" value="XM_047912985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKE8"/>
    <dbReference type="GeneID" id="71993715"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13837"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000160">
        <property type="entry name" value="Casein kinase I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="16"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="335"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO24141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="48048" checksum="774E96654CDEAE23" modified="2023-09-13" version="1">MASTSVSSSNVVGVHYRVGKKIGEGSFGVIFEGTNLLNNTQVAIKFEPRKSDAPQLRDEYRTYKILVGCPGIPNVYYFGQEGLHNILVIDLLGPSLEDLFDHCGRRFTVKTVVMVAKQMLSRVQTIHEKNLIYRDIKPDNFLIGRPNTKAQNVIHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQTTAIKDLCEGFPEEFNKYLSYVRNLGFEDTPDYDYLRDLFTKALQNNGEVEDGEYDWMKLNNGKGWDVPSRPSAREHGGASNADINRVALRASNTPQLDREKPLPSKPGAVRQPQQRSQQQLPPARRAQGALEPNVDRRSTAAQFQSSRADLAPPAAAAAPVRQAHPEPPKEGALEKLRKVLCCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKG3</accession>
    <name>A0A9Q8PKG3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4</fullName>
            <ecNumber evidence="6">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Carbon catabolite repressor protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cytoplasmic deadenylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">CLAFUR5_13150</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="26" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="6"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768489.1">
        <property type="nucleotide sequence ID" value="XM_047912298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKG3"/>
    <dbReference type="GeneID" id="71993028"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13150"/>
    <dbReference type="OMA" id="PHYYARA"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09097">
        <property type="entry name" value="Deadenylase_CCR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000037">
        <property type="entry name" value="Glucose-repressible alcohol dehydrogenase transcriptional effector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="17" id="KW-0804">Transcription</keyword>
    <keyword evidence="16" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="25">
        <location>
            <begin position="388"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="17"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="24">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00030493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00031469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00033317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00045495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="UJO24123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="760" mass="87245" checksum="706687DBCC2A275B" modified="2023-09-13" version="1">MADGFNRFNTGSQQYYYQNNHTSHPRSQLHHRNGSPINNNRALFNPNADTPSPNRSPGTNSPAHNPYSMYNNHNHRQNHSLLNGGAAHQNFQPQVNLGQAFAKNVSHAHQSHHLNNQHNDHAALHNTFGNHQHTVSNSTLSHTTPQFTPAHLQNGTPDHSSSIEPTNEHWADQLREYNKLRMAEQKVHWYARTAGSMNRFPGIASAGNNEHSQSEEHGERRRIADESDDMGSWDCMDLCGQGLKAMAPALFRHYPKLKKVYLNWNKIRSIPPQIGQMRFLTMLDLSNNDLHWLPPEIGMLTNLKKLNLYDNNLDDLPHELGSLYQLEMLGIEGNPLRPDLKEKLMQNGTKELIRFLRESAPKPEPPMDRPWRPLVEDTPEGADTFRLLSWNILCDRSATESQFGYTPKEALAWSRRKYMILDEMTGRNPDVMCIQEMDGENYNDFFRPELAAHDYKAVFTPKSRAQTMAEKEAKSVDGSAIFFKNSKYILLDKQVINFSREAISRPDMKGEHDVYNRVMPRDHVAIVAFLENRATGSRMIVANTHLTWQPEHSDIKIVQIAIMMDYINKMSSEYAKWPPCKDKELYKYNDADNLDGADGEKPEYLPSMKYDEPTQLPLLVCGDFNSTKDSGVYELIAQGSLSNAHSELGTNKYGDFTRHGMSHPFSLKSAYGNIGELPFTNYTPDFRQVIDWVFYSTNTMQVLGLLDRVDTEYMRRVPGFPNHYFPSDHLPLMIEFQVKERKERKVTETDFGNSRRESRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKK8</accession>
    <name>A0A9Q8PKK8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12823</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768493.1">
        <property type="nucleotide sequence ID" value="XM_047911971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKK8"/>
    <dbReference type="GeneID" id="71992701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12823"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO24127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="986" mass="109635" checksum="D8CB575DC1236A83" modified="2023-09-13" version="1">MVFCTYCGQSFTRDEHLERHILTLCVDTNVKPFKCFTCHMSFARRDLLQRHYTVHGRDQNQQEIPAANGMIPKSAGRTPIACSNCAKTKTKCDKKFPCSRCAGRNLRCTLRPTRRASKNANRVGIPPEGAVALPNGVIQTVGIENGAHPQPPTGSPQQQPPTFKPASPKNGMSAIPEEKSAAQPTVDGPPTQYADQPTSGPSPTDFSPAMNNGFINNTPMSGFHDLPHMSKDSSEAGSSPDFMLDWSQMQMPIGYDGMIAPHMLMNPDMGFDPNLVLADGHDDLLTIMPDVANGMAPPLITPLETPKIERSFSDMDLSRSAAAFHQHRQSMASVQSSSHSAPLAQADINGEMPAIVAAQDAWSVFKCTPIVPSTSCPKTAKANLERLEETLKNHEGWSTWSPQWEDADVAGGDHLTVMQLHGSTRDKLLAITQSFLHKALEIHREGHDRSSSGSGYHSPNSHYASNFVLLPPARVLEFFLRSYANCFERYYPLTSRGILDANELMHCYNDRASSLLVLMMIAQGAMNIPSTDARMLTGGLTEACRISLFDLIERNIIMSGDPIVLHSALLFTVQAAWSGDKWQMDIAMGQRGMYFAMLRHSGLLEKTSQQSNIVGAHPNADQLWNEWIQNESRSRLIYSWVLVDQDLALFHDTAPLFSVTEFGAPMPDADRLWNAKSAAAWSSIFEQVHEFSGGYSSIGSGARPLSLRDLFRHFLDDEMIPLGIEMTPLQLRLLLHPLQSLVCQYSQLLSCFSDVLSKRDDGNTPRKVSASSTRSRLEEVQSLLGRWFDLAERYLKANPTCPMMQTNLVIFHLISLNAVTKFPEVERLARRENFDGTYQQLAWTHKRCIHDIEEAVFHCGQVFRLIRAMPRGIRPPWWAGAIYRVALILWTDSLTHKESASPNNNGMFPVPGPSFAIDNLSADHPLIIRYLTKREGVPCVTKRDGSQMPLDRAYSVLQHSIEVIDEGASNRFADGIRSKLERLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKN6</accession>
    <name>A0A9Q8PKN6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768562.1">
        <property type="nucleotide sequence ID" value="XM_047913018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKN6"/>
    <dbReference type="GeneID" id="71993748"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13870"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="34061" checksum="5A489CF78E90CD84" modified="2023-09-13" version="1">MQNICNGKSCFLAQLQPLSDDQDCCICYEHVILPFTTPCGHTFCRKCLHQWTVDAPTCPTCRTILYLLPDAEDYLSAAHDDDGLDDFVVSDREAGYESDSTDGEDGERINGATARRLAADTGLITTTFATNHDKIIDHLTELYQRNDRNLDYNPVESDELVKLNYQSQIDACIATLLYLKPHRGDAHTLRDVCHRDWEKIAEIFHNVLRREDGEVMEARELYWELFDEVADYELIPEFSEYSQDVMRAHSARGGDCFGGDFYEFTARVVKIARDAYLESVEDDEFGLYMQAFQNWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL35</accession>
    <name>A0A9Q8PL35_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Riboflavin transporter MCH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13547</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768819.1">
        <property type="nucleotide sequence ID" value="XM_047912695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL35"/>
    <dbReference type="GeneID" id="71993425"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13547"/>
    <dbReference type="OMA" id="GSWMALT"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="237"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="284"/>
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            <end position="316"/>
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            <begin position="328"/>
            <end position="348"/>
        </location>
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            <begin position="354"/>
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            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
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        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
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        <location>
            <begin position="57"/>
            <end position="441"/>
        </location>
    </feature>
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        <location>
            <begin position="16"/>
            <end position="47"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="454" mass="49259" checksum="93CA1432EBE07FA9" modified="2023-09-13" version="1">MDVEANPVIHLVASRASAQQDRMDGKNNDVEEAREVSQEDAPDHAEATFPGDRGEAAAWVVLAGSFLALFPSFGLMVSIGTLQDYWQYHQLAGFSSRDIGWISGVFVYLALALGICFGPIFDRYGPRIIMFVGSIAYIAAIFLLAECKLYWHFMLCLGLLAGPAAAALTTIALAVVSHWFKVKRGLASGVAMVGNSFGGVLIPLVLRHCLPRYGYAWSVRTLGFVFTACLIISNLLVRSRFPPSPDAKKAKIFSLDLFGSGSFTFLTLSVFGIEVVLFGSLGILPTYASLSTDYPAATGFYLIAVMNGSSCFGRILPGFISDYVGRFNTLLVMMVFTLIVILVVWLPFGTSSLSALYAFTALFGFGTGSWMAMVPATIATLSGPHHFGRYFGTSYFVASLATLVCIPISGELVQSVGPRALVGFICVMLFVSIGLFATSRWCLLERRWKWLAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM10</accession>
    <name>A0A9Q8PM10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM10"/>
    <dbReference type="GeneID" id="71994050"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14172"/>
    <dbReference type="OMA" id="DEDCEYT"/>
    <dbReference type="OrthoDB" id="10671508at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="28"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
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            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="195"/>
        </location>
    </feature>
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        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="250" mass="24355" checksum="DB545464DFAAC58D" modified="2023-09-13" version="1">MKYQFTVAAFAGSAFASLEAYGAPPPAYGGEEAVSSSSSTSAAPTAPVYGGETTSSTAAPSTTAPASPESTTSAPTAPGYGGDKTVTDVVSSYVTYCPEPTQFTHEGKTYTVTAATTLTVCPKCEESTSSASESKTKQHPETTAETTAPTAPVYGAPSSTKPVENSPEQSTASSSALTAPVYGAPSSSSGIQTATVPAPYPTGNGTTPAGPTGTGVSASGTAPPAYTGAATQLAGGAAAGVAGLFAAFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQG7</accession>
    <name>A0A9Q8UQG7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">E3 SUMO-protein ligase pli1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06963</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906111.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71986841"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06963"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="11">
        <location>
            <begin position="107"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="296"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
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            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
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            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
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            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="551"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="617"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="664"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="687" mass="75250" checksum="95C88DA4198309D3" modified="2023-09-13" version="1">MASAGYTLQQQKGSVETRIKLLINSDLKEICKAYNYQVSGTKAVLQKRCIEILSDIVDRGDDNAFKDLNYRVANHGKSPPQPNGASVAASSNYPTPNGYHTNNQMAPGRPSAAQNRFSTGGRSVDFKPSPFYEVQDTVMGYTELHEMPQNRHTVRQDLRLTADQVTRLKADPSLRLMLYCGLSSGMNQWTTVDVAFPNQLEVKINDDDVRANFKGLKNKPGSTKPADITDRVRKNVGYPNRLAITYALTSKRYAFVIHLVKYISADALTERIKQGTHGGGVFSKTRVLQEMQKANDDDDLVATSVTMTLKDPISALRIETPVRSTVCSHNQCFEAKWFLQLQDQAPQWSCPVCSKSVSYESLCVDQYFEEILQKTPSSIESIHLQPNGEWQMIKEKEDAKPQGNSSRNNRASYDDDFDDDLIEIVEDQPAPKPALGGAAMPYSTPSLLSPATNSTFPLNTPPLSSRGNSAAPSMSSVAQSNKRPVSSVIDLTLSDNEEEEQMPRSGKRQQTGTSTHYGNTAQSSTPNSLPDPRFSYPAGQGQITDGYRQPVNATRPVSNGRSSGSGSYHSAQQQFGISGSASGTGSPFRTGISGSSAYNPPHNYIQSHTNPYGQWRPPTTQNTPTTSSFQSFSLRPPQPSVSPAQQSTHQSPDQAFRLPPVSTILPNGYNTGWRSDYHAGQSSSPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQL5</accession>
    <name>A0A9Q8UQL5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Dual oxidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06771</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763173.1">
        <property type="nucleotide sequence ID" value="XM_047905919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQL5"/>
    <dbReference type="GeneID" id="71986649"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06771"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="373"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="506" mass="57369" checksum="45CA57A5BED666C4" modified="2023-09-13" version="1">MYAMEGLYPVISKDFTLLSEKEINDFFDDLDKDKDGKITFEELEATLHEVHEELAPKLQKHHILHPHRRDLEKNAGHSKGDGLHAFLCRIMPECGAQLERKEFVEHVKRWEVPSQKQADSQENDKEDRAEEQRLPFRRRMRAYCAVHAPNILFVAFVVACLLGIGLWQMVIYIKNPAARAALGWGVIVAKACAGVLYPTLFFMVLSMSRPLSTFLRRFYALSRFINWDHSQKLHIIMSITGLTFATLHAIGHLTGSMLYGSRRGQGDDVASYLGASAVNAEGYRPYVWYVRSLPGWTGVTALGLFWTISLLSMPYVRNYSYEIFQLGHLLMFPMFSLLCAHGTAALLQTPMMGYWLAFPVLLVIFERVGRVAKGFMSVPARMKVLEGGDAVVITVKEPRGKDWKYSAGQYLLLQVPKISLWQWHPFTISSCRGDELQVHIKMEGDWTEALKDKMPVDEDIKVGIDGPYGAPAQRFYDYDYSIIVGGGIGITPFSAILTDLEENFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQX5</accession>
    <name>A0A9Q8UQX5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07570</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763488.1">
        <property type="nucleotide sequence ID" value="XM_047906718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQX5"/>
    <dbReference type="GeneID" id="71987448"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07570"/>
    <dbReference type="OMA" id="HIKWNEG"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="10">
        <location>
            <begin position="11"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="329"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="512"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="610" mass="68217" checksum="8EF9AD9B3C7CD41A" modified="2023-09-13" version="1">MSTRGQARHVRQRKLNTKQPLRIIRENEIDDAIDDESQRHIPQVETGVEKNEEVEFHLQAAINAANAAALGAKSKASSYIPTPEVRKAKGIKYDELYPKVFSQPATYIRFSSTVEDCVGVAYCMNEDDEKFLKQLNDGKDVNGQALKDKTIQCSEDGFEEVMNFLEDTSQRLQPFATVESSVPILSLDELEQSREEPLTAEAQRVVKPVYQYWASKKGSRPLLPTIKVRLLDTSLDADDADPYVCFRRREVRQTRKTRGRDAQVVEKLKKLRMELEQARQLVGMVRDREKLNETNLSVTRKVFEQRKQLKEVKVAKNIIGEKGEDEELLVNQKPVAKPKGRGDGSRPGPTIRLRSLGDSRSAPDSDLISLADMQAQADDHVDRTIESRKDQHRRWNKDWQDRTWDPITPPPEPADEQAKWAPLPAVGTGYPTPPPSLPSRSSQDRDGDVDMSEQKPVLDHDAVAGAEPTFNVFIPPPWLDNSAEDDEPDMKRVKLDAAPACRLRYGRGGRVHLEMRKQKPKGVLSRGVVSDSDSDDDEVDYFPVPDPKTFDYRSMLNSRARSGPEGVERRQFPSGDQTAMIAAAQQQASAAASGNASSPPKLVTAGSSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URN6</accession>
    <name>A0A9Q8URN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="96" mass="10178" checksum="B6AB394599762AB4" modified="2023-09-13" version="1">MYESNSSSSKASSTASQDCVQAIEQTTSHGASAVSGIPPSPEHVVGDLSLANVLAQGPVEPTDLPARADQQQALVKIEYQGPRCDDGTRNWVDYYP</sequence>
</entry>
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    <accession>A0A9Q8URQ3</accession>
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        </submittedName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8URQ3"/>
    <dbReference type="GeneID" id="71989732"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09854"/>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="22017" checksum="EA3367BFA4A860D4" modified="2023-09-13" version="1">MPGRLDPMFQIIERAQALIPRGNSFYRLARDLGFKKEYKKAKGMTEQLERLISPPAPGRRAEAMIGTVQSMWYALRTRRGLRWKSIQAVDKLCDELLALLMGEEKRELYRKMDSKIAMWNGFKRRIEDDENYRVSGGRVATPSIEDDDDPEMSGGSLDVEDYRGASAERTVAPRVESENVDQRGFPVMPKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US97</accession>
    <name>A0A9Q8US97_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bypass of stop codon protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
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    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910662.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71991392"/>
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    <dbReference type="OMA" id="AHGSYGV"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
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    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF6">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
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        <location>
            <begin position="112"/>
            <end position="502"/>
        </location>
    </feature>
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    </feature>
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            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
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            <begin position="76"/>
            <end position="97"/>
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    </feature>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="507" mass="54514" checksum="CC2371C86FA8C56C" modified="2023-09-13" version="1">MAALCRLAGGFSIDSDNNTSSSDTKHTRGPSPKELDAIELQDHGKLAQKTSSDEPVSPASIYTPGRKHDPFKTPEVSKTPNELESSQPPTPTRQTAASVVPSWSYPRMNKWRILCACLIYFGNGMSDSAPGALIPYIETWYSIGYAIVSLIWIANAAGFITAAFVTDPILKKFGRARTLMGSEAFMIAAYVIISCTPPFPAVVVAYLIMGFGNAINLALNNVFCANLADSTVILGLAHGSYGVGGIVAPLIATAMVSNGIHWSRFFLITIGVRAVGLVFAGWSFWNYEKEGTTQFANSLQQLATRQNGEVTKRHLLSRALKNKTTLIGALFIFAYQGAEVSESGWFISYLINYRNGNPARVGYVTSGFWAGITLGRFTLTHVAHRIGEKRFVFAMGIGVIIFQLMCWFIPNIIGEAVSVAILGLLLGPVYPCAATVFTKLLPGNMQTIAISFISSAGSSGGAVVPFITGLIAQGAGTFVLHPICIGAYVLMLGCWVVLPKVKKRAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USS1</accession>
    <name>A0A9Q8USS1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">CLAFUR5_11466</name>
    </gene>
    <organism evidence="3 4">
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8USS1"/>
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        <property type="component" value="Chromosome 8"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        <location>
            <begin position="502"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="525" mass="57112" checksum="E978672540DB8E7D" modified="2023-09-13" version="1">MCYNHKGQGIAIAWWRKTLQGATTQQLNRSWQFSSSVKDVVLGAKYFNFIALAALTAKLTIIDGTLLQEAFGQEVRADPAAAVNVTGYANTTIPNTGRVSGRAAQPGLLAKNFNDNLKIWSQGGGLLPNGWTTSATCLALQENLSAPLFYLGFEATYRDGNTPDTNGDDYSYITMNMIYTVAEDESEEGTGSCAGTKYTQTCMLRPAVIDYPVEIQAFNDSHTQPSMRLAVDGQKINNSTFRDFNTTLKQQNNFNIHETHTTVSDDSRTRLGGIAQGLNTYLGGNASIYYDAIAGFQLDQTGNAPVYLANDLGTQEGKTQSKNLCGFKYNNPMEPQTFKDNAAADPAHHYDVPSIVGKINQIMFATARDISNEDDDKDTAAGTLSRPATVYRDTIHYVTHFGYMWGAFASMISCILFVLPVYYGYWQLGREVTLGPFEIAAAFRAPNLYHESNAPIDKVIKEVGDRQVKFGQIVTGGDAGKIAVAEAEVVARIHPSASVGKSLQSWRASRHGGTSATTAPPGRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USZ2</accession>
    <name>A0A9Q8USZ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10927</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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        </citation>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    <sequence length="449" mass="50270" checksum="F7DBC11A61FAEBED" modified="2023-09-13" version="1">MENETGFIRKRAAPLLTRENHETWFKLMRIHLVSKQVDWVLEDIITDIPAATPSIATPSASSESSLPLDQAIRKASYRRHNATALYEMYICLSTDDQEMTYEIRHAKELWEWAEAKYKRRLLATGRSLLQQYTNFVMTEDQSIDDAWQELSSIARRAVSISPQFQDIKTEDRKIQQLLAALPDSFGSIRDAIDAQVNLSPQDILAILREKQESMIHQGTAMFAKKGFQGKLTCHLCGGDHFMSKCPHLSAAQQAVRNKDKLARVTYPAKRQPSPPRRRSSSPNLRDVLKVMTDLAKQMKESRKPKASSSKPARAHATQEDASDPEIPSEDDDVDEVAHSTVEAKGKYPSSEWLLDSCASSHMTDQDSLFRTLKPLQKRKWIKVGGGYLQATHMGSAVMGGPSGKQIVLENVLFVPGLGVSLVSWNQFSQQFAVQPPSFTLKSLSVGAMA</sequence>
</entry>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
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    </evidence>
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        <source>
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    <sequence length="109" mass="12160" checksum="261F7284AEF2B9F7" modified="2023-09-13" version="1">MNVELDLAYLRASHYAARPATRGQPHIELKLLAVLPGHQRRGVGSLLVKQGLEKADELKLPLFVISALQGKALYEHFGFQHIEVLPLDAREHGGHSEARHWSMLRPANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="7" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        </location>
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        <location>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="496"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="566" mass="63461" checksum="C72F67101F753612" modified="2023-09-13" version="1">MAEKETDPLDGLEERLQSHAKAFESLLALTPAREHYGSQIDDGLDPSEQWNRKKQTKEQKKAAKKAKLDPANQKTALDVMKDREKKRKRELRMDDEEHAEQAEADETTKTNKRQKKELSAEDEEAKRKAYVEKRKEKREKHREKKLKKAEKAEAKKAAKHDRDRAEAALENEATAGAESEDDDDDDAPLEQMDASELGKVDFSGLAASDDEENDDGQGDAAEASSAPTSPQVDSPAFDIATNHSEASSSSSIVPPSEEPKKAARSTSTSSKPGLKLDLSEQSKPMQKPLPKFDDIPSGTSSPKLQLPDIDQTQLQERLRKRIDELRARRKADGGEGKPAKSRQELLEQRRKKEEQRKAHKKELRQKAKEEEAQKREEQLRGSGSPLSTDIFSRASPRPQENNFSFSRLAFADGSAADASLSKVRDAKKRKGPQDPRTALQAAEKKQARINSFDEEKRKDIAEKDMWLNAKKHAHGERVRDDTSLLKKALKRKEKQKGKSAEEWRERQDNVVKGKEMKQKKREANLAKRRDDKGSKGNKKKPSSGKGGGGGGGKKKGRPGFEGRFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU31"/>
    <dbReference type="GeneID" id="71989252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09374"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="237" mass="25495" checksum="15DB21B6B7860D53" modified="2023-09-13" version="1">MERCGESLQAARQMKYDQELWDDANAAFVFPQHTTSVQGATKPSDVFDIVIFAGPNSSSGTTRYSAVLVRGTMSNRKTIMGGALAHNHAGALEKLLDQLCQLAARGDGLALEGSPVMVDEVDEANAQLCFPRHKLFDITTYAVSDPHAHISVVAEGVGPIDVDMEQAGMFESPKFRAVLVYLKDCVLARGPFCAGVKEAMEKLLLSLAMVVKTDEGCKGMQEAMEVGGGQVDKSLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUB3</accession>
    <name>A0A9Q8UUB3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767086.1">
        <property type="nucleotide sequence ID" value="XM_047911258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUB3"/>
    <dbReference type="GeneID" id="71991988"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12110"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="263" mass="29786" checksum="59BABC9246025EC9" modified="2023-09-13" version="1">MSSRTPSTSAASTHTTATDYTDYDAVAPDDTERKQAWNSIQTQLAGNEKRLSRHILVNLGLTGLPDATPHKIGMEGFGGIPVESIYDGASVLNQVDRDLKEAAPSTFKAHHTVDIIYPALDLLGDDLIPQATEPKRDGNLFGDVQNCTRYLGTTELKVVLYYDEEEGKGPGRADTRPRLRVRRKTKFVLDHRVKEVTKSTFFYEDDWDESNVEDYEIPYYYFYTRHGDPSQAPQLWYLDIVRLIGTLRKLTTWASSMLEPKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUS7</accession>
    <name>A0A9Q8UUS7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen assimilation transcription factor nit-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767579.1">
        <property type="nucleotide sequence ID" value="XM_047911309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUS7"/>
    <dbReference type="GeneID" id="71992039"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12161"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="310" mass="33825" checksum="BDDD228039A27ADA" modified="2023-09-13" version="1">MSGTGRPLLAARTSSGEKDSAGNTSPGPHRPHGASRAKRTLIESACSACRRRKSRCDGLRPTCSRCQNLRTDCHYEAEEGESRWSALRRRNQILEAERDQLRELMAFVQNRPEAEAQDIFQRIRSSSYDDVFMLLRAIKDGAMNMQQPPSAMTAMNVPGLPTAASGVDQRLPPIHAIFDHPRRPSPPAHLVHNHSLSSEDSTGSMPSELATNMSTPVPGAGPPPVHRAPLNTLEPSLQQHPHGYMRGTPATLSSEESTSSVLSTSLDGPPNFPPPQERSVAGPDPPQDERLPYYVNGQHVPGQHGGPYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVS6</accession>
    <name>A0A9Q8UVS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768662.1">
        <property type="nucleotide sequence ID" value="XM_047912521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVS6"/>
    <dbReference type="GeneID" id="71993251"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13373"/>
    <dbReference type="OrthoDB" id="10395165at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="559" mass="62813" checksum="9E631F3AFA95E024" modified="2023-09-13" version="1">MDNMSVTGREGSPKRRLSQSSLATDVENSPRRRRKPNTATLTGPSAKPSEPPDNILGETTNVLQPLPGSSSEKYGDSSSAEFQKIQAKATCESWEAGFEILQDKRGPSENGGVIALQERAEKLRSSGPRRHRLEMDALEKRIEILKQDVEQAQQQQDDSTIETNQEFAALMRKAREIYTMCSAIDIRGYLTSWNLPDPIFEQFDRCSELESQSKELRRERIRLQAEQIGKRDEIQVILARIFELRSSCSPGHEPDTSELETQIKQLRESPELLTLDKECQWYSAELDAVELDQSRAENTLYQTLEGYFLARELLVDKTVPDLGPENSPQDISVINSRVCCTPAAGSLEEADGTQDFATQLTKRLAPILKAHFQEARQELESSQSRLEALRDAGDIDPAERALAESPDHAIFLAKRERTREVIKAEEKFNDVCKRAQDAGIAGVPARSTGFSDHPSDGYGADTVEAHIKLTDVAGIEKWIDTETSSKKRVLFAQSDIVQMLEPSEPEERPDLEPLVLGESYSTIAQARQRGHIDVWLRMQTPQIVSEKDVFKSRGWRMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWI3</accession>
    <name>A0A9Q8UWI3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein TDA6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769412.1">
        <property type="nucleotide sequence ID" value="XM_047913377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWI3"/>
    <dbReference type="GeneID" id="71994107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14229"/>
    <dbReference type="OMA" id="DAIWYSQ"/>
    <dbReference type="OrthoDB" id="188042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009291">
        <property type="entry name" value="Vps62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174">
        <property type="entry name" value="DUF946 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174:SF5">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06101">
        <property type="entry name" value="Vps62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040135967" evidence="1">
        <location>
            <begin position="16"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="357" mass="38747" checksum="65CA6D565F315C59" modified="2023-09-13" version="1">MLSLALLSLALTATAAPLEPRQAPSNVPDFVVKFAPIAYLHTEEKYNPSDISTQLFNTHPAINRTTTTAGPNPLTLDNLNNLNTIANSGSPGGEDIFLTSNADPTTDPRPEYLYGVLPDAQGKTNGATSSAVITVQKGGGILDAFYFYFYAFDFGGVYFGLNVGNHVGDWEHTMVRFVAGVPQAIWYSQHSRGQAFTYQATKKGADGVRPLVYVANGTHANYATDGNHDHTIPGVNLPFGPIEDHTDAGALWDPIASAYYYSYDVSSKSFAPYNDEPTNWLYFTGHWGDAKIPEDDERQKCAFGIDALCEYVGGPTGPAFKGLDRKDVCPDGVEGGCHILPFALAKRDKEVWDDMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4Y0</accession>
    <name>A0A9Q8L4Y0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">U3 small nucleolar RNA-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755223.1">
        <property type="nucleotide sequence ID" value="XM_047899766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4Y0"/>
    <dbReference type="GeneID" id="71980496"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00618"/>
    <dbReference type="OMA" id="MWDVELP"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046351">
        <property type="entry name" value="UTP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="889" mass="98110" checksum="0A50B3FFFB1E7546" modified="2023-09-13" version="1">MDVHRSRFVQFPAHPITAVAFSRSTDERLPPGVEQPALKLAIGRANGEIEIWNPLQGRWVQENVFSGDNKSLDGLAWTREPDETDTEGQVVVGQHRLFSIASSPAVLEWDLQRGQLKKKSTGNFSAVWCFAAQPSHGTSDPSAQELVAGCEDGTIVLLTTADNDLQFKKFLARVSGKKARCVSIAYQKRDRVVAGFMDSTIRVFDTRSSSVVRTMSIGAGIPGAPKNTIVWSVKALPNGDIISGDSNGEVVFWDGRSYSLTQRIKGHDSECLDVVPSSDGKTVFSGSLDGRIAVHRQSTNANGRRSWANSHHRKVHNGEVKVMSAFDSNGLSVVVSGGADPVPVAIPLQEYGKENNRPLPTVPQQAPVISARHARLLVSWWGKDINIWRISRRAEVETSPELQPPRRLVARITLNTKHNIRRVSISDDGKVLAASTNAEIKLFQLRRKPDADALGVRRLHVPKTLATLGARAMNFSPDSKWLAAVTPDSEVHIVRITADLSNPKHVRVLDKVVEVERQNRVDTSQSGFKLYDQAINQLAFSADSSVLAASDLSGHIDSWVLEGHEDPTAPPVDVSQEDSKHGDSDDSSEDSSDDDDNVYIFYGQHWTDNPAGRLIPKLDSAALILTFRPTADSAVANAAVNGNPGIHSTRHNPYAHSHELPAGRHLLWVMTASHEMYEFDVLAGKLSDWSRNNPTPVLPADFARLRDRVIGAVWDVAGGRERLWLYGTSWMFMLNVGGNLLDSHSRKRRKSEVAEQGLKRLKTSSGAGLKTPSHHREGLPQSLKRLEDGTWTEVALDRPIKHDEDVDMDEAIESDTRLALTRIKSTDDEDQIVNGGASQQMHQRTWWCTFKYRPILGVVPIADDAAVDEDKPLEVVVVERPLWDAQKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L521</accession>
    <name>A0A9Q8L521_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755353.1">
        <property type="nucleotide sequence ID" value="XM_047899951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L521"/>
    <dbReference type="GeneID" id="71980681"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00803"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="19140" checksum="769BF252C7494B6E" modified="2023-09-13" version="1">MFVFGFEATKFTHIETLDGRQGSINNVPDHSGHARGSNDEEKRPKTLAADTDVELDTPPRNLSVVHLKPNIPRKTYWQKLALTTTSPGSWIIGDAPTGLTFVRNTFSTIFVFAMPAWIAGVGTANVFNTIGAIGVLMLSFVAFFIWRGKDTRVKTAKVYRYHAVRQFNGRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L561</accession>
    <name>A0A9Q8L561_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755295.1">
        <property type="nucleotide sequence ID" value="XM_047901398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L561"/>
    <dbReference type="GeneID" id="71982128"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02250"/>
    <dbReference type="OrthoDB" id="2988756at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32142" checksum="31E4F7945A8810F2" modified="2023-09-13" version="1">MVILLVRLATHWHQHRRLNATTWIVISSILVLLARTICNALILRWATAFSPTSGTTPSMARVGSILTLISRVLVTTYYWLQSIELLLFYRDMMAHIPWICRVIKMTWLVLAGTYTAVVLATFLECRPITLYWSLTPGSTHPCRRAYTQLLLQCLSNALIDILLLTISAPILQAQARAFPRNLQLGLLYILGFFCIIVIGVKIHYIYRDGSVQHARSFWASIQVVVATFVANAPSIYGGVRKERRRRSSVADPLGLGRVRTAESGGEMGVGLALGLGREVSPVLVLGGGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5C2</accession>
    <name>A0A9Q8L5C2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Maleylacetate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755470.1">
        <property type="nucleotide sequence ID" value="XM_047899971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5C2"/>
    <dbReference type="GeneID" id="71980701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00823"/>
    <dbReference type="OMA" id="HAMSHQV"/>
    <dbReference type="OrthoDB" id="3360544at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018506">
        <property type="term" value="F:maleylacetate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08177">
        <property type="entry name" value="MAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034786">
        <property type="entry name" value="MAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF105">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="260"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="340" mass="36797" checksum="1B0242A3787EC699" modified="2023-09-13" version="1">MESFEYNVNPGRVVFGAGSINKLPEEIKRLNLSKPLLLSTPQQRNQVVQLEPILERGGIQKAGLFSNATMHTPTYVTNEALTYAKDCGADCLVSFGGGSTTGLGKAISIRTGLPHISIPTTYAGSEMTPILGETADGKKTTRSDPKILPGIVIYDVDFTMTLPPALSATSGVNAIAHAVEALYARNTNPVMNLLALEGTKSLAESLPIIVNDSQNREARIKAQYGAWLCAMCLGSVGMNTYDCVAARHSIQRSKDPDVLRRLADVLPESDGDAINGLNVLLTKLKVKRGLKDFGMKEEDVDKAAEIAVSNPYWNPRGVEKEPLRETIRRCWAGEEARADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5S3</accession>
    <name>A0A9Q8L5S3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_01548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755695.1">
        <property type="nucleotide sequence ID" value="XM_047900696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5S3"/>
    <dbReference type="GeneID" id="71981426"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01548"/>
    <dbReference type="OMA" id="IHDSYSM"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="28150" checksum="C6C1029029FD8A0C" modified="2023-09-13" version="1">MAEQLPNAPFPAPPPFYSHFTKPNIARLRQLRREAGVPVAPIDATADATSKEDIDIFALPVELRHLIPPEPQADGKYTVFGNAIDPDAAERSLAERDVEQLYPSDGSVRLNPQPHLIGLTRSMLTTFLALAGILSQNPELYEEKVKDIHTIAMNIHELINQYRPHQARETLIMMLEERVDKMKKESQDIDQAKAKVVKLLQDIQDMQRTHAPKHDERNMRDGMVQVASVTKRKARQRAAWATLRQEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5T1</accession>
    <name>A0A9Q8L5T1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755757.1">
        <property type="nucleotide sequence ID" value="XM_047901166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5T1"/>
    <dbReference type="GeneID" id="71981896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02018"/>
    <dbReference type="OMA" id="WFIRGIQ"/>
    <dbReference type="OrthoDB" id="5342507at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="30206" checksum="4C771ECF703D6A6A" modified="2023-09-13" version="1">MGIFKGGALRLFQTFLYALLFACAAVILGIYSYFLAVLADRNTGIATRWKAVEGISGVAVLYLIFAVLLTCCLGGISFLAFLAIALDVAFVGGMIAIAILTRDGASSCSGNVRTPLGNGPASTDSSGYGNFGAGDNENLTYAVSLRTACKLNTAAFAVSIIAAILFLITAGLQVALVRHHKKEKRYGPSPKNNYTSGFGKRKFWQRKPKDTTTRDTELGAGGLAAPGPDMRPSHETGLTGSTVGNTGTYDKVAHEPAGAHTGYYTQPQGTGVSPYGYDARTTGTATNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6C2</accession>
    <name>A0A9Q8L6C2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_00983</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755384.1">
        <property type="nucleotide sequence ID" value="XM_047900131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6C2"/>
    <dbReference type="GeneID" id="71980861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00983"/>
    <dbReference type="OMA" id="CWATIYK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="122"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="222"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO11018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="34346" checksum="95293F077544F1A9" modified="2023-09-13" version="1">MAKGDADQAAKTFMGMPGFVVDFLMGGVSAAVSKTAAAPIERVKLLIQNQDEMLKTGRLDRKYDGIMDCFRRTSADEGIVALWRGNTANVIRYFPTQALNFAFRDTFKSMFGYKKERDGYWWWMAGNLASGGMAGATSLLFVYSLDYARTRLANDAKNAKSGGDRQFNGLVDVYKKTLASDGVMGLYRGFGPSVAGIVVYRGLYFGMYDSLKPVVLVGNLEGNFLASFLLGWTVTTGAGIASYPLDTVRRRMMMTSGEAVKYKSSFDAAQQIIAKEGVKSLFKGAGANILRGVAGAGVLSIYDQLQVIMFGKKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6N4</accession>
    <name>A0A9Q8L6N4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756174.1">
        <property type="nucleotide sequence ID" value="XM_047899365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6N4"/>
    <dbReference type="GeneID" id="71980095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00217"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06869">
        <property type="entry name" value="PX_UP2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="252"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="937"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="937"/>
            <end position="952"/>
        </location>
    </feature>
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        <location>
            <begin position="964"/>
            <end position="983"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1000" mass="113488" checksum="68AFF96DF713E8D0" modified="2023-09-13" version="1">MTVEHLLLPMATQLNGGPKEEATAPVAPTPFVTRSKTVESQAFVDAPETQDEQAAAAQARRTRLLRSPTQGTMTSTASVPPPGSLLTGKQEHYLKRELISAQTQWEVSELSHPTALQRFGAPFRSDRGEVAPEHSELPLLRYIFVHHVRNFPFLNQAKEKEFWQDKLQAFLESFANKHISSAEDRLEQTKRAKLAQKANKLVELMMVSGIPTASGYEERIRFSEMEVVESGPNEEGLVVNVPEGHEINGWDINVAGVRLVSVKRHVRQHKHAEFLLRVKRRDEPERYVARRFGEFARMHKKLRLELPGKVLPPLPKKNKAQSLYSGKDDDDDSDSVSSMSTTGTGTPTTAEASESNGSGGGFRSYLSSWTGGGSTSTRHGRNASKASLAAPSASPRASMDSSADKASQSPLRTACPQDTVLHREDQRVSLRAFLRNFLQNEAIANSKSMYDFLTAQPITLNDEERADIDKRKHMDSKRLEEQRQFFEIARQRARDLDVHMEKFRRSVVEANGLRNLFAEIKQKEKIDDLNPEFRKFAEWLRIEVAATTYHLFLAEDNSPELFAQAKRIHGLVPYSALKQVIRFTNPAAVMSSVLDLFMAQPLGAKSLLQRIFGLALGDGIRSLQRSIDSLTVKIDEPALCDKIKNYIEGIEDVRDNVRTQAREEQVDLLVKVLQSDEIEPQLSSKQIERVFNAYVAWDNAVENVDEEMRQGAELFARLKQLLKLHTRRRDKQMMLELVEESNTLRLFRDLFQIFYEPLVRVYKSANVYNSVTDFARFADDAIQTIEKAQRQDVSADPNQTVQSFIDLCERHEEDLYKFIHEVHKHDNGLFDKLMAWIEGILDFLRNGPKGGKLDMNALFAGALEIKQIDKDKALKEINSLIKWQTARKRWHSDKTRQKMASGGNENADVMGGLASTFKPGDFGLNPIDLQDLNMEDDEDFDSEEEDDEDDADPIAAERKRRQRRQDVLKRTAGEPVKPEITELHKMNPQFLSMLRMVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Q7</accession>
    <name>A0A9Q8L6Q7_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 21</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_00975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Q7"/>
    <dbReference type="GeneID" id="71980853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00975"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000611">
        <property type="entry name" value="RAB GTPase Vps21/Ypt51, putative"/>
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    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
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        <property type="entry name" value="Small_GTPase"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="136"/>
            <end position="159"/>
        </location>
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        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="25539" checksum="396B4B6379CC56DF" modified="2023-09-13" version="1">MSDTTGAAAPKPSSSVKLVLLGEAAVGKSSLVLRFVNNDFQPNKEPTIGAAFLTQKCQLPSRTIKFEIWDTAGQERFASLAPMYYRNAQSALVVYDITKASSLVKAKHWVAELQRQASPGIVIALVGNKLDLCDDDNADAEQTEGENETEEDTSTARKVSTKEAKAYADEENLLFIETSAKTGHNVSEVFTAIANAIPETSLKGPRGGAGGGTQAAINAGQSNSNVNLNARSEAGAKEGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L771</accession>
    <name>A0A9Q8L771_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">DUF2433 domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="4" type="ORF">CLAFUR5_00445</name>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L771"/>
    <dbReference type="GeneID" id="71980323"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00445"/>
    <dbReference type="OMA" id="NYIIHTG"/>
    <dbReference type="OrthoDB" id="3918848at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="entry name" value="MPP_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF2433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056812">
        <property type="entry name" value="RRM_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF11">
        <property type="entry name" value="DUF2433 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10360">
        <property type="entry name" value="DUF2433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25061">
        <property type="entry name" value="RRM_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2433" evidence="2">
        <location>
            <begin position="285"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding" evidence="3">
        <location>
            <begin position="547"/>
            <end position="611"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="722"/>
        </location>
    </feature>
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        <location>
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            <end position="418"/>
        </location>
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        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
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        <location>
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        </location>
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        </location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF10360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="76792" checksum="3A8C111C8F23B4CE" modified="2023-09-13" version="1">MAQPPSQPRAYSQAYLPNGGAQQPSGPVPGARPLDPNQGRVQQLGHARVLCIADVRGNLRQLNELARNAKADYIIHTGDFGFYDDQSLERIAEKTLKHVAQYSPLLPEPLKADIARTGPQQSIKDRFRQERLPLSELPQFLNKSQRLDVPVYTVWGACEDVSVLEKLRSQEYKVDNLHIIDESHSRLLDVGGIKLRLLGLGGAVVMHKLFDNGEGRTTIAGGQGTMWTTLLQMGELIDTANRVYDPTETRVLVTHASPAREGLLNQLSVQLKADFSISAGLHFRYGSSYNEFSVNPSLDHYRGKLSASKASFNDVWETVKHEVEPAVSENEAQNKLLQGALDLVSKMPTNASGGNPFGGGGQINGAVDESAFKNMWNFNLADAAFGWLVLDIDQGRIGTEMRAQGFNFSHRSGKTPQRAQGLPQAPINATMQPTGGVLPTPGQQPPPMAQQQARPPQQANNVPPQQRSQPPNAQQQARPGQQQSPAPGGKPATPQAALTANGTTAPTANLPTKDLPQTNGTSAAEVAKPETPFQNKQANAGQSPQQQEPSKGIFVMNGPSSIDEVKSELFTPEDAAKITDVTKAGPPGRWAVHFATPEIMQEVLKTGQPKEAGEKYKGVRLTVYRPNPSRGNYGGAGGWGPGPRGGHSNRGGPEGRGGYQSAGGATTGSDSESGRGGRGRGRGGAFRGENRGGRGSRGGRGGERGGKPDGAAAAAAPAGGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L806</accession>
    <name>A0A9Q8L806_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756858.1">
        <property type="nucleotide sequence ID" value="XM_047901094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L806"/>
    <dbReference type="GeneID" id="71981824"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01946"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="410" mass="45615" checksum="CD7CB5D5E5571588" modified="2023-09-13" version="1">MSASTTSPPTTNRGSPPRGKQTSKPTTSYSSDDTSDDESDADDTPVSPVHITYFEEIEQPEPCRRSTSSFDHRDEVDVHQKVRHDEQSGGADFKEQVTRPVVASSGGGGHENYLEEFPLSRFPHELFILNSKRYWKGLEPQYLITTKLCTLSWDYHVNFKHSVDKVVSADTILYCVVCKSHQHICLGPWDITDYIHAISRSYRSICNSCSVGDVQGKYARSWLDGVKSFYKELEAVGGDVNAMEIEEEVDDEESADGGEDGDEDEEEEEEDDDDEENDEDGGLADWSGRIGGLAMVEENIIIEHAKDGDLAEEHEDEDDDEEEEEDGEEEEDGALVEWSDRNKDLAMVPALDQSFTSDVRGLFDGFGLGSGARSDVATAGTTGRKRKSEAQMQPETPSAKLLMRFPDLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9A9</accession>
    <name>A0A9Q8L9A9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuc-1 negative regulatory protein preg</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757440.1">
        <property type="nucleotide sequence ID" value="XM_047901890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9A9"/>
    <dbReference type="GeneID" id="71982620"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02742"/>
    <dbReference type="OMA" id="DWKIVPK"/>
    <dbReference type="OrthoDB" id="337735at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="44967" checksum="6B3CE209582D0591" modified="2023-09-13" version="1">MSTTISSSSSPANSPRSSFHVSSPRASFAPPQRSPAASRASPRFPASSSASAAYNTASSPRRAFNAPTTALGPQQPKQHFVESGLVAASFAGYVDASTQYSPDGFPPTAGRNVAIAAGKGRPPGRSASSVRKRKDAQSSSDESSPEPMSGTNTHRSAARPPAPAEPQLRSDPDRAAGSINTAASSSSNEPQEARSTHGYSNAPKKARAEGTVKVMPSKYETCNPKDLGALMSHMLMELIRINDQIPLRDGRLTRFHSRAPPGISVSDYLQRLIQHATLPPPILLSMVYYIDRLCTLYPAFTINSLTVHRFLITAATVAAKGLSDSFWTNPTYARIGGIPVSELATLELDLLQRVNYRIVPKPEVLEEYYASLVDRTDGYIIEAGSSSTSLSSGSDGGKDEANNDDQHMGNEPTCSSYQMKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9N4</accession>
    <name>A0A9Q8L9N4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757711.1">
        <property type="nucleotide sequence ID" value="XM_047901981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9N4"/>
    <dbReference type="GeneID" id="71982711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02833"/>
    <dbReference type="OMA" id="RSCHWVV"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="261" mass="29059" checksum="9D20A48370D426B8" modified="2023-09-13" version="1">MSKSEFVDLIKPIGERMVHYDPTKPPNDQPKNDATDPTRAVPQGFIDAMIVREEVYVQEQKVPLENELDEDDARSFHWIAYASIPAKAVANGNGSGERRSSNTSTKIAIGTIRLVPPPHAAHPGHEPTIQQTNSNGEKEAYIKLGRLCVIKEFRKAGISKLLIETALAYARENPYEVGPHLDPASMEALKKGLALNFKGLVVIHAQTGVAKIWKRYGFEVDEGMGKWDEEGIEHIGMWKRIDVTDGRRKSKIWLATNPTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA95</accession>
    <name>A0A9Q8LA95_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03810</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758156.1">
        <property type="nucleotide sequence ID" value="XM_047902958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA95"/>
    <dbReference type="GeneID" id="71983688"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03810"/>
    <dbReference type="OMA" id="GISFPIM"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000011">
        <property type="entry name" value="Cdp-diacylglycerol-inositol 3-phosphatidyltransferase pis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="302" mass="33536" checksum="3BE8B527DBAA15D6" modified="2023-09-13" version="1">MVQDVVEEPRLRQANGHANGRPLNGKPRGPEIQESDETDENIFLFVPNLIGYSRIVLALASLYFMPLHPRRCSFLYSISCLLDAADGIAARKYEQSTRFGAVLDMVTDRCTTTCLLVFLATAKPAYSMIFQGLISLDLASHYMHMYATLVMGGQTQSHKNVDAKRSYIMNLYYTNKAVLFIACALNELFFIALYLLCFSSPIITPALIQPQSPANPISPEPSLLFPSPFSAGAMELARANKMDSTVPWVLTIASAPVMLFKQWVNIIQLVKASKWLAEGDRKDRKKLGLPRKRGGAKGKKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAC5</accession>
    <name>A0A9Q8LAC5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_02775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.67" evidence="1"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758202.1">
        <property type="nucleotide sequence ID" value="XM_047901923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAC5"/>
    <dbReference type="GeneID" id="71982653"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02775"/>
    <dbReference type="OMA" id="YPKRAYR"/>
    <dbReference type="OrthoDB" id="16692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14497">
        <property type="entry name" value="PTP_PTEN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF81">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="97"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="567" mass="61983" checksum="8561054E6112CFE9" modified="2023-09-13" version="1">MDLLRQIVASPRARHPEAGLDLCYVTDTIVATSGPSGTYPQLAYRNPLKDLVKFLDKNHGEEWAVWEFRAEGTGYPDEEVYGRVRHYPWPDHHPPPFNLVPLIMGSMRNWLKGKEAEGKKRVAVVHCKAGKGRSGTVSCSYLISEEGWTAEDAMKRFTERRMRPGFGNGISIPSQLRWVGYVDKWTKGGKIYIERPVEIVELQIWGLRNGCKIGIEGYVDEGKVIKTFHTFQKSEREIVRGAIKKENGFADVALEAMGKKKAADKGDAGEQIKEAEKAQKEAENSDSDGVVNGGGDVVFRPSTRVVLPTSDINIDFERRNKSKYGGFTMVTSVAHVWFNAFFEGKGPEKDGNPDESGVFEIDFDAMDGIKGSSRKGTKCFDKMSVVWKVLETERQPSVVITEPDDGAEIPQARPADWKGGDQKSEDTEKKLGLRTATTESASVSRASSMREDKDSPVDSPKDELDTVRAVGPDGRDLGGGTQASGESSGLKQEQSISDTTPVLEQLKSEGSVSQPGAPVTGMTDTAHGHISSSTSALPGGKAEEKLKDAKEHAIGSVGMFKKDHSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAE2</accession>
    <name>A0A9Q8LAE2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758231.1">
        <property type="nucleotide sequence ID" value="XM_047901494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAE2"/>
    <dbReference type="GeneID" id="71982224"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02346"/>
    <dbReference type="OrthoDB" id="10571804at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="18258" checksum="F2C1692D9739D654" modified="2023-09-13" version="1">MFKVRCRYACSDKTFSTSGALRDHMRRTHNLVPDTLVPGRDYTICNRCQRKLLWYEYDKHIKHQKGKHKGEVRSVLILLIGVRWRVQAEGDDGWILTGGALFEDVLEVQVQRAMILDVHLAKALLLRIGRSRMLRGQLLGSVIVLVTCIKLTGRSQCDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAH2</accession>
    <name>A0A9Q8LAH2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758055.1">
        <property type="nucleotide sequence ID" value="XM_047902728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAH2"/>
    <dbReference type="GeneID" id="71983458"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03580"/>
    <dbReference type="OMA" id="NNRYARA"/>
    <dbReference type="OrthoDB" id="1936594at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="610"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="644"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="447"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="961" mass="106843" checksum="E8BF9B6330A85346" modified="2023-09-13" version="1">MSDTLLTYLRASLPAEVARLAGTHLKHLEEGEYKTLLESEEARILLGQENDTELSSITPEDFKSWNDFVFHRLGAFCGNRTQPERQVILFCIGYAALLAFVQANVTGPPLEFQPSALVLPQTDGSGHDSRQKVRQQLLSSLTVDGIAPYKLTPHIELLCLADAVMTCPAVLKNVKAARWAKIRVAFLQQRLLSEVSSTLQNVIYDDIELLLEDFKTYSGDRANLEAEFLLERATIHTHHSLDKFARADLDQAKNDRKFEFALTGLMGKRTKFQQKDTSQLLVLAKSHLDTESATTAGAQSQTTAENGNEESTRPANLDLNDDTLLESISFTEKPSEAPLAEFKDREDLPPSLRELDPSDQPQLQPLDSIILLSLASSIKNTSPEDGLTREETLPYATRVLEGGSSNWQVYTQALLVRSRIEGYRSRTVERGLLQLQTLVDQVIADTATEGSSGEEGTEVSAPKTTSFLPKAKESESAPVAERIRYIFQLATPTRWELEAELATRWVQLGGLRSALEIYERLEMWAEAALCHAATEREDKAKRIVGRQLFYATNEGPDTPASEISDEEEWTGPAREPPPLDAPRLYCILGDIDQSIEMYEKAWEVSNERYARAQRSIGRHFIQAGNMVRAAEAYSRSLKVNQLNQQSWFALGCALLELAQFSKAVEAFSRCVQLDETDAESWSNLAAALLHTDPEDEAHPTESVKLDDEDEAVTSTTTAAERAQNIRIEALKALKRAASLKHDSFRIWENVLIVAASIRPEPDWTSILSAQKRIIDIRGPADGEKCIDIEIMTKLVNHIIATSDTYDPSQPGLTRMVVKFVDETVVPLITSSAELWHIVGKLALWRNKPSTALDAEEKAWRAVTSQPGWESDSEAKWNNVVDATVRLVDAYESLGQRERTEGMAAGSGELVAKDWKFKARTAIRGILGKGKDAWEDGTGWEKLKESMEGLRGCSLALHAGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAN7</accession>
    <name>A0A9Q8LAN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758237.1">
        <property type="nucleotide sequence ID" value="XM_047901488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAN7"/>
    <dbReference type="GeneID" id="71982218"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02340"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="264" mass="29561" checksum="2920CE498215D103" modified="2023-09-13" version="1">MARTRAQRKVAAKKVAAKKDSGEAARQVANTYELVEQIMIHLCDLEPVEIIRMEAVSKTFQHVLRRSKTIPPSLQIPRVKDLSRRFNVTTIYADGLPPIFLHFDITGRRVLVPDKPEISLLATIDQNELRDEKWRTGGMWRSWPVLQPNTTQISRVSVSGLGAFSPAGMSTGKYDVSLKHTSETAISLGQLGDMAYELQDLSGDFTNVQFDFAIDEAGDSTPWRSDLRSYDHIARGQKVILPEYGKAMAMARAMKELWKGNDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAS1</accession>
    <name>A0A9Q8LAS1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758364.1">
        <property type="nucleotide sequence ID" value="XM_047901867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAS1"/>
    <dbReference type="GeneID" id="71982597"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02719"/>
    <dbReference type="OMA" id="RDLYAKW"/>
    <dbReference type="OrthoDB" id="40334at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42336:SF1">
        <property type="entry name" value="ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT C_ THIOL SPECIFIC ANTIOXIDANT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42336">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21288" checksum="54990A8B599E8787" modified="2023-09-13" version="1">MTFVQEFNSWFAPTAPTGMYASDPPKIGTEAPRPAKLAIEPSKQTIIAFLRHCGCPFAEKTFLNMREAARTHSDIDFIAVSHSEEEHTQKWLKSLPQYGSDPGNLRVVTDSEREAYGAYGLGTSGWAHVLAPSALSSVFQLSKDGISNRPTESGSRWQTSGTYGIGADGMIKWGGPASRSDDMPDFEEAVRELGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBF7</accession>
    <name>A0A9Q8LBF7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 17 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758680.1">
        <property type="nucleotide sequence ID" value="XM_047902886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBF7"/>
    <dbReference type="GeneID" id="71983616"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03738"/>
    <dbReference type="OrthoDB" id="6474464at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="44760" checksum="8B67FE80E5EA685A" modified="2023-09-13" version="1">MVAIIRWARQHKRSIFVAITLTLILTAFIIHRHDTSRDHYLTADIAHHAPLAATAGQVLLSPGEAKSMCRANDFPTYKKQNRKVYEILLINTELDWLEVGLHELGPYVDYFVVVEADTTFTGIAKPLHFKEDSHLFKDFQHKIIHRAVHDPIVSSRIWDHEDWFRESSLHEVFPSLEGTEAEANDGDALLVSDMDEIVRPGVLLLRYCDFPSRLILRTDFFYYSYQWRHRGPQWSHPDATVYRGRNTLDPNALRQGLLGPGWTPIAALRRWWDRATIWNAGWHCSSCFATVAEMRFKMNSFSHQPWNTPYCRELPVLTDRVRHGKDLFGREGENYDRAEGNRDVPAYALEQHEKEGRFKYMMTRDGEDAGFEDWKDAPHSDPKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBT0</accession>
    <name>A0A9Q8LBT0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758889.1">
        <property type="nucleotide sequence ID" value="XM_047901480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBT0"/>
    <dbReference type="GeneID" id="71982210"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02332"/>
    <dbReference type="OrthoDB" id="10642555at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="499" mass="52895" checksum="1DB065B170A871D6" modified="2023-09-13" version="1">MDSRDATRRLSKSRTRDTTSYRTQKPERINTKKNTDTPTDTTINPPPISNRTNTSSRSSGTMSSPNRVSKEWVEANKATRNCYHGGRNAFYEGLPPLGFNLKAAVYGPGAAQWRIDARAHQQAAAAATAAASQSAQQPPQASSSRRTSTRPARAASASQQASSATQAAPAPPQITSSPIPAGRAVRALAPQSPRHDSQPEIEDATFRTPDGARPALPGSSSSPELRSLSQSPELPADLAARLTGTAADPNLPTSTPNDPADALRGRNRSTRIANLSPQRAAAATPSPRNPAPHKEKRAPRLDDSNRPYHSPAHTMKRSRDRYRWAPQQNTAGGQYIAPNAGYAVAMRDVAVIASQALVGPPPVGYEGPTAGLPTRIGLVGGNEDPVIRGLQGEMAEAVIEFLEREARGEEGAEEEGNTTLTNSDGAAEGEEGGGEGGDVGAAREERVVPGSQESLEEVDEAADDDGEEGPIAAPVGGVPQWRLNMSEQEQEEWDRQMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDN2</accession>
    <name>A0A9Q8LDN2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear transcription factor Y subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759941.1">
        <property type="nucleotide sequence ID" value="XM_047907249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDN2"/>
    <dbReference type="GeneID" id="71987979"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08101"/>
    <dbReference type="OMA" id="KEPMDPG"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="9">
        <location>
            <begin position="52"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="147"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="20852" checksum="3CE5011337F3B33E" modified="2023-09-13" version="1">MSASPEHEVEAEPAATGSPNDNENQPTDEQNEEGMSRPEDVGYDFEVKEQDRWLPIANVARIMKTALPENAKIAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAMTSLGFENYGEALKIYLARYRENLVARGDQKPAAAGGAGNSVTSPSYDNANHNALGLEADGTNDFAYPGQGADSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEF8</accession>
    <name>A0A9Q8LEF8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box/TPR repeat protein pof3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760277.1">
        <property type="nucleotide sequence ID" value="XM_047904048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEF8"/>
    <dbReference type="GeneID" id="71984778"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04900"/>
    <dbReference type="OMA" id="MRDLWMR"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="128"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="566" mass="63176" checksum="EC984996FE109D67" modified="2023-09-13" version="1">MSADTLRREGRIAYGNGEYDKALDLFRRAVKRGDPSATLLDHLAATHEKLNDLDDALKAAKKTIQTWREHPTGYLRAGRILVKMGKKSTALDIYNQALKVVKHVGIGYEELKKAQADVLKDVAPPKSVDPLTVLPREMALMVLEYLSFRQRTAISRVSKGWRDFIRSEPNLWRHLDLTGARARVLNKFISAAINTAYSKLEAATLNRLNDFDKVLAALASRPSLQSLTLLETGLQGQNLVDVLRKAKGLRELRILHGTDISQTVLHSLARQHSDRLELLQCARVRHISFGSTWHFKLPMLTTLDLTADTIDAILLCANLSENSPKLRSLTLRELTTPTLLPDLGFLDLRQCQNLEYVRLRLRFTSPQQLTLPPSVKVLDLATSCGGSYVGSNFFISMEGAANDQAGLKWSRLPNLLDVKLHFPGAILSDVVGPFNITHYEGKEIPDISKLESLCMVNPNIPSNTILLEERLIDLEHWAITGCLDLKDDHVESMIRSYKKLRSLDFSGSSITGIAIKEIVKAGHVKELVANDCLQVGRDAVDWARAQGLKVQFGNTSNQITGKKVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEM0</accession>
    <name>A0A9Q8LEM0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_04728</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760482.1">
        <property type="nucleotide sequence ID" value="XM_047903876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEM0"/>
    <dbReference type="GeneID" id="71984606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04728"/>
    <dbReference type="OMA" id="EQTVEYV"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
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    <sequence length="89" mass="9465" checksum="24E07155C09FB2E3" modified="2023-09-13" version="1">MSAEPENGGGDGDARDPSGFLSEIIGAPVTVKLNSGVVYKGELQSVDGYMNVALEDTKEYVDGKHRRDYGDAFVRGNNVMYISSDSASS</sequence>
</entry>
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    <accession>A0A9Q8LEV0</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO16113.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="100"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="17848" checksum="86D7E70F0CE5545E" modified="2023-09-13" version="1">MSNSHLADHPRGHTYRGIGASGNAHVHLGDQMNINARRPEEIILASLRFRGMEHYRRRPLETYPGTYRWMLDDSTSNDTYDPCAKQKFGFENAARWQHGNNFRKWLTSSDGTFWITGKPGAGKSCLMKYLFEHQRTKELLQTWAGENVVLAGFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG94</accession>
    <name>A0A9Q8LG94_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">INO80 complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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        </lineage>
    </organism>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761263.1">
        <property type="nucleotide sequence ID" value="XM_047903921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG94"/>
    <dbReference type="GeneID" id="71984651"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04773"/>
    <dbReference type="OrthoDB" id="2021186at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1"/>
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        </location>
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        <location>
            <begin position="9"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="149"/>
        </location>
    </feature>
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        <location>
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            <end position="234"/>
        </location>
    </feature>
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        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="387" mass="42837" checksum="4E29F9C588C1ACA6" modified="2023-09-13" version="1">MPPARRSARTVSSTSARESAQPYARTNARTSRSPTTARSSATIARPANGKTSLRLTVKAPPSKLRQATSGSQIPPNPYANDQSESDATPAPAPRRSRATRNPRTVVDPDSDEDDDDEEDEDAEGEVDQELLANEDDSEEDAEGEDDEMDELSRDHPPPPVIIQQRVNGQARPNVAVTAPNEGPLKSVEDKEMEDDDDDELSELDDLDELEPDNEEENEEEEEEDDEDGSDEDDENSRSATPDLTKLTKRQRGAFSGTEEFDGGLMALSNEALKKKHLTEEEHAMRRQEMARRRKNLSEKRNEEEKMDTINKLLSKPAPKRRTRAEMQALRAAGAAGGDDEEDKPDPIYTRWVSNKEGSRLGVPAEWMDAPVGITFKSGGGRMVEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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    </reference>
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            <end position="169"/>
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            <begin position="186"/>
            <end position="239"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
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        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="34980" checksum="F809F761D287DF8C" modified="2023-09-13" version="1">MPAIVKAQTTKQAKAAYKARGRPTLSDKESRQLQRAIQLEERAEKAREAEKRRTEAAKKRAEKERPAKGDARLGSQRRTDKFGFVASQFHLGNFFGKPRMPSEVAKAGGAGSGVMPRDVDTEDEFGSEDLDDDTLLKALDSPEAKKRSVVSPGVMKRSDALSMPPPPRPVVMASVQARVPVAVSRSSGMAIAPPSRPSLPNYPQTTPNGTTKPGVVSRHPAALMPPPPRPFVGTSKARPVPKPIVQEDFASFWDELDSSTQVARDLEGPVEDKRTDSFCSGDFDMTEEELDELMPPDLGFTSTQLETFIDDDIQLSQAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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    </dbReference>
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        </location>
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        </location>
    </feature>
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            <end position="309"/>
        </location>
    </feature>
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        <location>
            <begin position="360"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="49661" checksum="ED1EE6A43B48A53B" modified="2023-09-13" version="1">MPIDDPSLIGVADKPGSDSMDGIENSQDSGKSNSDANGTRESSAASLHHDESHCSELWPERYGWEATKRFDNHIDCGFHMGLDLERRSFSIVANWYLHLYQGQGGVFELPVEKMCYDGERRFIDAVGSAGSHIAASIHLQDRDRGKKIWSVTEEQGTDLETYIHKKLSEDERLVELVRSEKYQRSVKKAVCCCPHPDRKGRKSFGRHIIDAIENFFDLKGVKVQAAHGLVVEHRSPPEAFLCRYRWEEEDDFDARDEMWRSSDDESIGERNVNEEGGEQANAGSSNEMRPSSGNGSSGERNANDRSGQVANIGLSNEMRPSSGAGERRETDADDNGDQSENNNGRASEGDGGARVPGLEEIDRPRKDMDENAAGAETQSSNDGTPQELWPADYGWEGVKRVVGWETKEFGRPVNGEWNLVWRKDGGGWRSGPDRLHVELECLEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="10758" checksum="9A9A9F520B0E4605" modified="2023-09-13" version="1">MAKDPPEQSQQPQLPSSSGVTVSNALTGVTGTVGAVVGGVTRTTGGLIAAVGRGAGGTFNNATKTEPVGNGIQAVTDGFNYGASAVSRGLEDLSAGKKPGSTDSTWDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH64</accession>
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            <fullName evidence="5">NAD(P)-binding protein</fullName>
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        <lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO17351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761717.1">
        <property type="nucleotide sequence ID" value="XM_047904677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH64"/>
    <dbReference type="GeneID" id="71985407"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05529"/>
    <dbReference type="OMA" id="IYCCTPS"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000577">
        <property type="entry name" value="Proline utilization protein PrnX, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="51713" checksum="842AD3DC0E39808A" modified="2023-09-13" version="1">MPLTVLGNQDVTRILHSLNKDDILEVQQSLADALHWYSTSADENDFCSDFQPERTQLKRKDGSTTLFMPASGLYGQGVKVLNITSPDDARGLPALAENMSLSSDGDSKSFISSTRRQDSMASTNTNSPNSSLHATTSPESDRSLKAPLQSENSAVATVKGTLTLLDNEGNTTGLIDAEELTAFRAALASTMLLKKRHSVHDLTVFGAGRQAYWHIRLALLLRGPEIHHLNIVTRNFESARQCIMRIYNPQLDDPNFVDHIGQRYNSKTKVNLLTPMHTEYQRLLKEYVRASNIIFCCTPSTSPLFPATYLTNPEGRKKGRYIACIGSFKPHMVELHPDILKYAVAPHHEQKHIHKRQKEGGAILVDTVTGCLKEAGEVVQAKLTPDQAVELGELLMLKKDAEQRSHSKGEKSEEGCHLQDNSGLKEWLTRGDVIYKSVGLGLMDVVVGNELLGLAWSRGIGTRIENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHF4</accession>
    <name>A0A9Q8LHF4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endo-1,6-beta-D-glucanase neg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761906.1">
        <property type="nucleotide sequence ID" value="XM_047904544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHF4"/>
    <dbReference type="GeneID" id="71985274"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05396"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="13164" checksum="2BCA560E887901C1" modified="2023-09-13" version="1">MPIQNELLYSTAAYPSMYIYDYENALLIKNRIAPALTQANLMTQIWAYDHNIDHHRCPQTVRDNTSVNTVAWHCYSGGWDVLSQSHASNPTVLQYMTECWTPSTSPWYNAAAFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ52</accession>
    <name>A0A9Q8LJ52_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS-type efflux pump MFS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762722.1">
        <property type="nucleotide sequence ID" value="XM_047905071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ52"/>
    <dbReference type="GeneID" id="71985801"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05923"/>
    <dbReference type="OrthoDB" id="4426556at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF61">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02780)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17144" checksum="C599FD51B51E8C5A" modified="2023-09-13" version="1">MIWFGWTSFEDVHWIAGTIALGAFGVGVYYIYLSATNYLADAYEKYAASALSAVGFGRNAFGAFLPLATPALYKNVGFQWASTMLGIIGLVLSLVPFVLLIKGPYLRSRSPFMLDACLDDDEATGRRDSIAEMQQGRQERKGSAILPWSQVRSASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJV8</accession>
    <name>A0A9Q8LJV8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJV8"/>
    <dbReference type="GeneID" id="71987627"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07749"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="612" mass="69129" checksum="024E7EE8E43EAD55" modified="2023-09-13" version="1">MWLLNAQSRKLQDFVDFREVRGKYAILSHTWGKEEFTFDMIHDPGSRNMLGYIKIDFACRQAQEDNLEHAWIDTCCIDKRSSAELGEAINSMYLWYLNAKVCYAYLADVDIATIAEPLSAHAPALVGFDSYQQAVDNPTSPGRKNGLEFHLHVSEVQLKLQQLLGQSKWFTRGWTLQELIAPGHLRSYDHRWVAVGTKTELVASLSQITLISPAILLDQRQLSKASIAQKMSWAAHRTTSRIEDQAYCLMGIFDVNMPLLYGEGSKSFMRLQEEIIRTWDRIDHSILAWTGGGGLLLAPSPAAFTGQHHLTSWSLPQRDAFELSNAGLRISVLADVYDCFDPDQPRFDERRYVLVALNARSVQPSAAQIGLTLKKRIHIDTTDLRKSWTSETEDIVYERQLGLKRIDASQLRNFSKVELTIARNTYHLPRTTNKVLVTSECFNLRAETSITTDIATETEVYLYASLNADVAQGKVTLLPKTESDPDASPSSAELSLELVQRYDRHRLPELRLLTCRGNHTRHAVSFFEPGEEHIHRLVGLTAQRIVSKYTILGSEFMWHLHISDCERLPQQSGAELSMPSSHGECSIVQAPIQRLSLRSAACEKAPVCKSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2M6</accession>
    <name>A0A9Q8P2M6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755466.1">
        <property type="nucleotide sequence ID" value="XM_047899507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2M6"/>
    <dbReference type="GeneID" id="71980237"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00359"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
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</entry>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <location>
            <begin position="114"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="13492" checksum="4BCA3C5177890816" modified="2023-09-13" version="1">MPLSSTPVLRIAASVLGTIFIAFGANAILNPASALSFFELAYPDGVLQKDAKLAVDALSIVYGVRDVFMGIAIYAAAYFGTRPALGWILIAAGGVAGVDGYVCKSLVGSGEMNHWGYGPIVAVLGLVSVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P401</accession>
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        <recommendedName>
            <fullName evidence="5">Phosphodiest-domain-containing protein</fullName>
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    <organism evidence="3 4">
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        <name type="common">Tomato leaf mold</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756921.1">
        <property type="nucleotide sequence ID" value="XM_047899677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P401"/>
    <dbReference type="GeneID" id="71980407"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00529"/>
    <dbReference type="OMA" id="DGHKFGP"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.180:FF:000003">
        <property type="entry name" value="Type I phosphodiesterase/nucleotide pyrophosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="77415" checksum="4CD786EC1293D4EE" modified="2023-09-13" version="1">MTSRDSGSDDGLTRTSGEVRQHDRETITAEEAERLLTPSEKQRDQHHQERDGDSDKRRKRRKSGWLGERDGETAVLYKVERGGGRSSSAESSANSSEVDIQHLAKTDAKRKSKASWYGKLAAIHIVIIVAFFALLFGAYKASHAGRASKGKTDAMAQVLSNGTHQFAPTTILISLDGFRADFLHRSLTPTLSGFVREGVSPKHMLPSFPSLTFPNHFTLVTGQYPEAHGIVGNSFWDPNMAKEFNYTDPEKSMKPEYWNAEPLWSTVESQDLKSAIHMWPGSEAHILPEPTYVDNFNADEPLDNKVRRILGWLDLPGPNDVGASLEQPRPQLIAAYVPDVDADGHMYGPNSTYIRSTIAEVDGMLGSLFQGITERNLTDVVNVVIVSDHGMATTSSHRLIQLEDLIDPELIEHTDGWPLYGLRPKDQSEEQLNKLYKELVEKQMLPQYRGNFEVYLRDYNMPARYHFSNNDRIAPLWIVPKTGWAIVTKTEFNIEEALARDEVYHPRGLHGYDFEDPLMRAIFVARGPAFPHPQGSEVEPFQNVEVYNIVCDSLGIEPNPNNGTLRLPFITVGLHDLTAVPDIPDDSFEIDLDAAILPPNLPGLDKVPEAPNRPTTPSRPSDEEASTPPTQPDNAFNPEPSVERPVVQDGKDGEEAKKQSWLDWINAELDGVKVWAGSLFGSGKGGEEGEGEDGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P468</accession>
    <name>A0A9Q8P468_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-sulfomuconolactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757131.1">
        <property type="nucleotide sequence ID" value="XM_047900179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P468"/>
    <dbReference type="GeneID" id="71980909"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01031"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="15"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="30590" checksum="61AF5E49C6933E04" modified="2023-09-13" version="1">MSRLAARIPKGSWCTHMHVVDPGTFPLDKAAQYTPSPHTLDEAKSFLGRLGIEKMVIVQPSIYADDNACTLDGLRQLGTTNGRAVKQFDPSATSQLQLQEWHDLGVRGVRLNFKSVGATPSGEELKQALRAYADVVRPFGCPLELYISLENVPLVDAISHDLDDTKMVIDHFAHPTAASLKGAKSAHEIEGFPSLLSLLQKGTLGDSNDLIVESLCKEILRARPDRCVFATDWPHTRFEDVAIAAYLEKILDWIDEEGVSLSQVLVENAEELFDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4J7</accession>
    <name>A0A9Q8P4J7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">J-type co-chaperone JAC1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757310.1">
        <property type="nucleotide sequence ID" value="XM_047900303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4J7"/>
    <dbReference type="GeneID" id="71981033"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01155"/>
    <dbReference type="OMA" id="TVELKYW"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="31"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="23419" checksum="41D47146D8A106EB" modified="2023-09-13" version="1">MSRPVARAIGSLSRRTFITSRTARQQEVPQSHFDFFPQTYPQGPPPHATFTPDLKQLRKEFLQLQAKAHPDLAPASQKRHAEALSARINEAYKTLQDPLKRAQYLLSQHGIDVDDESAKLSESELLMEVMEAREAVEEAENEEDLIDIRAENSERIDKSVAILSEAFAQEEMDKAAREAIKLRYWMNIEESIQGWEKGKGGGIIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Y2</accession>
    <name>A0A9Q8P4Y2_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757700.1">
        <property type="nucleotide sequence ID" value="XM_047902166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Y2"/>
    <dbReference type="GeneID" id="71982896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03018"/>
    <dbReference type="OMA" id="KGEPIGQ"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="285"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="66140" checksum="CC3B6D6CBD9BC389" modified="2023-09-13" version="1">MPGVLAPEHQQAEKARKPTKNELRRAKKKQKKSDAPVETPQSDSNAPGQPAEPIQPVEPSKDDPIQDVPAVENDDELPTDDPLFSQFAGVFAKFKEEDKEDPALKEPEKPEVFYDDDDNIQDEDEEAETKQRSSKKARKMANKLSIAELKAIVRKPEIVDWTDTSAQDPKLLVNIKSSRNVVPVPTHWSLKREYLSSKRGIEKPGFALPKFIAETGISDMRDAVLEKQAEATLKQQQRARVSGKTGKLDIDYQKLYEAFFRRQTKPSLTRYGEVYYEGKEFETNLRHLRPGELSEELKEALNMPPGAPPPWLINQQKIGPPPSYPALKIAGLNAPPPPGGQWGFHPGGYGKPPVDDQNRPLFGGDVFGMTMDEGSQKDTTQAEAVDKSLWGELQPPAKEEEEEEEEEDEDEEEEEEDDSGRRTGLETPYGGTETPGGITSTVPTDFMGSRGLPDEMNLRKQRLGTETEASSHPRSAGQVLNERSIRNEGFFGGERAYDLSGSNNIPVLGQEQSGRKRKAGDLDVSMDPDALLRDDKMSKDELRRQYDAQRAQQNPGGWQGGAADGEDLSGMVAEESAKRQKRDKERAAQRGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P588</accession>
    <name>A0A9Q8P588_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell division cycle protein cdt2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758002.1">
        <property type="nucleotide sequence ID" value="XM_047902164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P588"/>
    <dbReference type="GeneID" id="71982894"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03016"/>
    <dbReference type="OMA" id="RTAHNNR"/>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="327"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="626"/>
            <end position="656"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
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        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="693" mass="76760" checksum="C2CC59C33239977E" modified="2023-09-13" version="1">MTDMPPPPMSSQDSGIVCHSKHKMQFEQENQMPTPPASSPPTFQDFSGNLLHIPKIKKPPTVTPKRFTKFFTPRSSMSTRAGRQSKAGRQLQDITRNGSNCRRTGLNHQDDFTPKVEDDGTAERLFKRRKISTDLPSSPPQSSPLEHVQATRELPVFHDQVPGSPTISEADTLPELFEKLKPFPKPIRRLREPGRSRRLLERSFGGYDANSRGLRGVDHAVDARAETANFVTTPSDMHPFRGAALPFCTAACNTNSLIAVGDEEGSVRLIDSASSAQFSASHVKFRVHHNAVMDIAFCSDDYVLATASGDQTARVVDMYSQQTVSILQGHQSSVKQVRFQPGNDNMVTTSARDGTVRLWDLRASGRSAVQSFRDGVDRGEEMEPQTMTSQELHVGYGHRSTTRKYEMDERNELSITSFQHLPHGRSHLIVTASEVNASVKIWDLRNAGFGQRNASPLASTPLPETHRGTRHYGINSMALSGDGARLYTVCRDATVYAYSTNQLALGYVPEMSSGPSRRRMMKDPKAGLGPLYGFRHPNLRIGTFYIKAAIRPAKGDHGEMLAVGNTDKCPILFPTDERHLPKPERIYEDAEEDEDDLPTAAPSFPRSSGTTPSTGLQVHEHGTALVRAHNKEVTSLAWTTNGNLITVSDDFSARCWREDAAKARELRGMGEVGGGRWRSGWADVRLEWDEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P607</accession>
    <name>A0A9Q8P607_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758914.1">
        <property type="nucleotide sequence ID" value="XM_047902950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P607"/>
    <dbReference type="GeneID" id="71983680"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03802"/>
    <dbReference type="OMA" id="TEEWHKV"/>
    <dbReference type="OrthoDB" id="71302at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11398">
        <property type="entry name" value="bHLHzip_scCBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000144">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047206">
        <property type="entry name" value="bHLHzip_scCBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="4">
        <location>
            <begin position="181"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="299" mass="32743" checksum="66A155751FFEB303" modified="2023-09-13" version="1">MAAAVKRKRGADDLPDQRPAPGMHESDFGNPYQMPGEEEAHHDMNFAAALSHHNNDMEGHEHPQHDQGHHPQGHEEMHEGGIPSASDTAAAAMAYHTMTVPQSTESAFMTQPTQEPGDRPGSAGVDPNNPNAQRTSSFGDFDNILPKDGQNAPNGNMSPGGAAGNQSTPKPQVGTEEWHKVRRDNHKEVERRRRETINEGINELAKIVPGCEKNKGSILARAVQFITQLKENETQNIEKWTLEKLLTEQAIAELSSSCDKLKAECQRAWGEAEQWKKAAQKAGVSIEDEKADADAEDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6K1</accession>
    <name>A0A9Q8P6K1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short chain alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759484.1">
        <property type="nucleotide sequence ID" value="XM_047906964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6K1"/>
    <dbReference type="GeneID" id="71987694"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07816"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="30943" checksum="08C7B1BE45F18B3C" modified="2023-09-13" version="1">MANSDRNNNKTAIISGGARGIGRCLVRRFLEKGYRVFVFDIDEEELKHTTHVHLKKYTDSKALGSAICNLRDVEDIRKQVKQAAEFLDGEIHVLINNGGIAAPKWKDEKTMFDMDTIGEWQAYVETNLTAPFAVSQACLPYMKNAGANAPINNHDDADSDAGPCIIHIGSFRAYQSDPNQEGYASTKAGQLGLMHSMCISLQPHGIRVNLIAPGRIKVAHESKDGDEKGLEWAQLNEDKDVDDHPANRAGRPKDIADAAVYLVNAGFVTGQDIVVDGGATKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P737</accession>
    <name>A0A9Q8P737_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759848.1">
        <property type="nucleotide sequence ID" value="XM_047907853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P737"/>
    <dbReference type="GeneID" id="71988583"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08705"/>
    <dbReference type="OrthoDB" id="5238236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="1">
        <location>
            <begin position="14"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="864" mass="97746" checksum="EADDBA2503F23112" modified="2023-09-13" version="1">MLTDSHAPIGGRYRMYKEGGDRITRWLVSTASSCRRSWTVASTARGKVSTGELLKYAQLISSWKPPIEIPGNITELLQDVVIGREVCAEFYASQDMACKGHQHMIEVLQKVLAVLLEARRKRKKEKTKGKQAHALPEHAEATQLKTKEALNNLFENLQIEEPCEEAWATAPKKRPTQPAVPVDWPTLEVDEKEEKMFVLFCFLKDMQEMRALVKDTWQEYGEKKIAAVTASMVTEAALGIMSCANETLTEAHPSFAEVDDVLAFLHLRLDTDADGKPGLYATSSVEQGQAVDNELTQMLCPEAIALTKGLQGLFSAARATARDRKANGASTKEQWRYEEKVTPPGVFSLSSFGTLLYRLFPDLFRLVKEHKDCKGFSNEFQYGLVQVGAGNLACLWFISAIQLYSEIDKLTKGGNTPFYQYCMMDARTHRVMSQVYDSQIGQTAQRSTLYLPIIEEAKKQFEQAFIGNIAALKYDQSYQHTLMIDENWLPAEVWTSFPAWSGIMIDRVFTWQSHVKHSIANDASIILASAYLYKACRHGNLVLQRWKDMDWFLEQAGQEGPFIHEVGPEGNMATFSRRLFIGIGMSAASFSRDNDRLEARGLRSEKQMFDQRRVFETGSAFLRLAEQLADERRISGKPKRWCMQTALQKEMSRRMQEQVGRAAKRRRRQVAFTGLEMLKFFKQQRLDDEPGLHFDLIAFFMACRRMLWDVRVRWKGEQLASRPEWDHILVAEVLQDGQSAEDEGKPLTSSAMGDAADVLEEYISKQGSRYTDEAFVLARGEMPVNWTDEARALVRSEVPAAWLADVGHYFEAEMLPGSATSDRSSLSAQLGPVLRSERSCTCAKVEDSPMYQAKVETVAEDEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7F6</accession>
    <name>A0A9Q8P7F6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760430.1">
        <property type="nucleotide sequence ID" value="XM_047903894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7F6"/>
    <dbReference type="GeneID" id="71984624"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04746"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="219"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="50077" checksum="E9C26819C2A82392" modified="2023-09-13" version="1">MTDTEPFTLIEEQNHNAPYRLWDDVLDLNSAKSADHDLQYAEHLRRAFPGYIVTGIPAGNINLLGFAASGFASAERDKDTDMFWSWKGYTGPAAGSRNGQLAEAVHFAKYHYKWGNEDFILYTVGGVQYVLKERKWQEHPLGPSKVTDALITAIGQYILSDVVWVFDSYWYQSKPLFQEIKKASWDKVILDEKMKKELVSVASKFFDSKDVYDDLGVPWKRGLIFHGPPGNGKTISIKALMHTLLMRKHSVPTLYVKNAPQAYQLNSVFSQARRLSPCMLVLEDIETIVRPQTRSYFFNQMDGLEHNDGIFVVASTNFLEKLDPGLTSRPSRFDRKYLFPLPNEHERTLYCQYWRGKVSHKKDIAFPEKLCPAMARITPGFSFAFLQECFVASLLTLARQNTLEDDDGGLEKYELWRVFKETADVLRKEIDPEKTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8E3</accession>
    <name>A0A9Q8P8E3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-keto-3-deoxy-L-rhamnonate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761480.1">
        <property type="nucleotide sequence ID" value="XM_047904029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8E3"/>
    <dbReference type="GeneID" id="71984759"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04881"/>
    <dbReference type="OMA" id="HYLALGC"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF9">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="3">
        <location>
            <begin position="37"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="24163" checksum="4C3CE16F45A8B678" modified="2023-09-13" version="1">MSPPPPTCPTPQTTNVKNSRLRLLNALRDGQYPLLAFMALPPVRIAQIVALTGLDSIIIDGEHGHISDDSMHNSVAAISALGVSPVIRIRGPVHDIIKRALDTGAHGIMVPQINNAEEAQQIVASSKFPPQGVRGQGSAFPAIAHGLTTPEYMKSANETLITMIQIETKAGVENVDAICAVPGVDMVFIGPNDLAIDQLFAGRYAFQVWLAVAWPVTDLPLIQLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8K2</accession>
    <name>A0A9Q8P8K2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nonribosomal peptide synthetase fmqA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761453.1">
        <property type="nucleotide sequence ID" value="XM_047903564.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71984294"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04416"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19534">
        <property type="entry name" value="E_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000002">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF12">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE IVOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="955"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="2318"/>
            <end position="2391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2391" mass="264781" checksum="617061FD86A83AD3" modified="2023-09-13" version="1">MDNPPASIMPPGCHNRETSGRYSPFSLLPPSIDTTIAIAHAAQLCRVDSSQLQDLLPCTSIQEGLMALTTQRPGDYVATFIYGIGANVSIERLHQAWDLVAESNPILRTRIISLPTVQGHVLWQAVLDVPLSWKTENEGDVDAGPEHQMNLSEPLTRMSIIKPSLGSGPCCPYWKIHHALYDGWSINLFLGEVERAYYRQPESGLRQMQHFIRHLQARDESAEKVFWSQYFDGIRGAHFPSVPLDSHPRPDSQITFDMTDLPLSHCDYTGATIVTAAWATVAANEAGASEALFGLIVTGRQAPLKDIEFIAGPTIATVPKRVSLDWRSSHDHLLDNVQKGAAEMIPFEQTGLRNISRMSESAALACKFQTLLRQQSHLLRDARPASDNYSIVTECHLEKDAIHARFSYDSKVVSPQRAEFVLMGLHGPRWDLHQVWAWNSAVPEPTRACVHDIVSRRVIERPLALAICAWDGNLTYEYLEDLSTQVALHLSGQVLSGEIIPLLFEKSKWMPVAAIGVMKAGGACLALDSGLPPVRLQNLAAESRASLILCSVKNSTLVQQIGAQKSVVVGNDCQWPAGESSVLPQVNPSDKFYVNFTSGSTGIPKGALNTHEAFCSSITYQQRRLGFDEFAPQCERDNDLAGCLERYNVTLVDLPPSVARIMSRRALSQLSTLILGGEPVMPEDAYLAGANTRIVNVYGPAECTPTATLAEVKPNDVSIGRGAGVCTWIIEPQLQTICPIGTVGELWLEGPLVGEGYLHNQEQTKDCFVENPPWLTQGVSGSCARPGRPGRKGRLYRTGDLARYRNDGSIVFVGRTDYQVKIRGQRIELGEVEHHVQQALPPDISAAVCTEVIQPQVAKGKVVVAFISLRGEASTAMDQESHNAAVHNLTEGVISRLTDSVPLHLIPTAFIPVLTLPRLSSDQIDRKALRTLGGGTHLKQRNVDRKEAIHGAEKQHVNRIEAILQQIWVSVLNLTKAEVSVDQPFMRLGGDSITAMQVVSQGKLRNVSFTVTDVLEASTIRKIARRCKIMETQHSPNGDSNVDADGVEVHNRPFDLSPIQQMFFQAYPDGLNHWNHTYLLELARPVRAELLRDALEALFARHAMLRCRFHRDEATGKWMQRVLPKDDAHPYLLREHHVNCRDEVVGISQARQESLDLQRGPIFASDLFHIASNGTQLLLLSSHHAVIDLVSWRIVWADLEDFVNHGKLFSHPTASFQQWCHQQYTIGASLSPLSVLPYPVPKPRSEFWGLPESENTFSGCETHSVSFDQDLTSTLFGGANDSLHTEPMDIMIAALTHSFMQTFPEREPAVVWLEGHGREPPVEIPLDITNTIGWFTTLYPIPLALSAQSTLVEAVRLAKDNRRRVPNKGQPYFACRYRSQSGREAFQQHDLPEIVLNFSGEFQQLEATEGLFKRAETTGMGDQDIEEISLSAKRTSMIEINAEREKSQFMVTVYIHKRMKHQDRLKGWIDSFSRALVTAAQELAVLDPTFTTTDLPLLPLSPDNLQRLLIEELPRCGIHAKAVSEMCLCLPAQEASYSTSNTWRCVPSDAARSTVSTSRLAEAWRTVAKRHPILQTVFVTHPEGDGFVQVVLRQPITRKVNIDAGEERPVDVLMRLESPQFAPHEPKHAFSICWSRSGEIAYRLDVNHSLVDGTSLGLLLSELTNAYDGVGMEPATPFRDVVQHVTSIPKAQRLSAWGALLRNIQPTRFPIQACHNEDRDVRERFGNKSLPRSAVEGVADFCKSADVTRFVFMQVAWALVLAHFTGPSDICFGYLAHGRDAPVAGIESTIGPLISLLVGRVDLRQLASKVLEDVSKTTLKHRSIQHISLADLQHHLGIPRGLFNTSLSVRRTDESPRNPSLTFETQAGEDLHEFDIGVSVDGLMDVIVEYRESCISAHVAHEASSVLIDAIRYLLTTAGDDDLTVDKEDGYAASRFFKYLVGSDEPSAKVFWSEQFTDTQASHYPSRPFGRSTDADDEVQLDIPGSLDTCFEMATALRTAWALLVCRMTDSREAIFGVPTLLRKVESQGHSIAKFGRTGLHWIMSLSDEASFACDFQTVVELVDEATGLPSKYPGLTHVRCILEREARARLSLRFNTSSMSKQQAERLLDQLQYIITLLLDEAVREQTLDCVNMTCKQDLEQIWQWNATTPSAPCICAWDGVLSYRQLDDLSTQLAQSLVAESVVLVMKCGAVAVATDVTTQPEERLLAMVEQVGSSMCLSSVKHKDLASRLCTSVTVVGPALLHRSPHVNGQPLPQVSPDDALLIQFTSGSTGTPKGVVVTHENMCSALAHQRDALGYRQDSRVLDFSSYALDVFWANLLKLFQKLWAEILKLDPATIGVDGGFFRLGGDSIGAMRVDALARQNGLPQLTVRDVFRHPLLRDLASAVEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8Y8</accession>
    <name>A0A9Q8P8Y8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761959.1">
        <property type="nucleotide sequence ID" value="XM_047904976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8Y8"/>
    <dbReference type="GeneID" id="71985706"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05828"/>
    <dbReference type="OrthoDB" id="10551054at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="31726" checksum="E3B79D56A2DB1464" modified="2023-09-13" version="1">MAATGAKQTAEDMAALLLVIKEANKLMSKRKYECKHRRALTKAEVPKSTLLRVTPEHEKNATDLVQGIRSMVDEYRGEGDSPPEFWPYYDFLRDAKYIADFPGGLDKAMDLVKEFGLEYTEMCGLYGGDHPPSRGEMDYDSTMLLFYHTKVTAWTSTQLLEWELDLDVEGLLTGDPAVTRKTGGSYQSNRPPTRHFYYGHSITRGNIEAKMWPHTLRYLKALHAKKIACIVVPKVAGHRLSVELVDMIIEVSYDKAFTDTPLAISAADNDEKHRRYREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P961</accession>
    <name>A0A9Q8P961_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase orf2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_05653</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762083.1">
        <property type="nucleotide sequence ID" value="XM_047904801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P961"/>
    <dbReference type="GeneID" id="71985531"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05653"/>
    <dbReference type="OMA" id="PETWQPK"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11059">
        <property type="entry name" value="CYP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="60465" checksum="99D9E139045D921E" modified="2023-09-13" version="1">MINIPVTAALALLCLAVYKFFIYPTVLSSLAKIPNAHWSSSLSPAWILYHRQRQDDTTTVHAAHQRLGPIIRLAPNEISINSVDGGIRSVYAGGFEKGSWYSNVFSNYGVEPMFAMEGHSEHSKRKRMLSNVYAKSTLQSSASLTKQTDVLIKERLYPRLKAAADSEEPIELYDVFSAVTMDFVSGYIFGMNNGSDFIRDEEAGIKLFHDFKARQKYTFWPQEMAAFTQILEKVGLKWLVVPKWVDQANQEIEDWLIAMCDRAEQTIQMAEAGEKVRTEDHPTVYSQLRNTLSKDASRQKGITGGLDQSDGSRIRIASELLDHTLAGFDTSGITLTWLAWQLSRADNAPWQRRLQAELATLDQSLDAKSIDNLPVLHATIMETLRLHAAIPGNQPRITPQTTTTLGDAEAGIMFTNLPPGIRVQAQAWSLHRNPRVFPEPEVWNPERWLNEQGELRNDPRMARWFWAFGSGGRMCVGSNLAMLDMKATVVGIWSKFSTEVADDEGMVPNGGYMAEPLGVGPGGKKGIGKGRKFLRCRLTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9F3</accession>
    <name>A0A9Q8P9F3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetyltransferase pyiB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762368.1">
        <property type="nucleotide sequence ID" value="XM_047905310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9F3"/>
    <dbReference type="GeneID" id="71986040"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06162"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="413" mass="46041" checksum="E58380578FF62C45" modified="2023-09-13" version="1">MDIYPAHVLDNAQNYRKILMSYMFRFNDIPDGQQLVDSLLALLKIGDWRKLSGRFRLNENGKLEIHVPRHFTSEAPAITYSHQVFAASVDTHALGKWLPPPGHHSGVRQCSGLRDFVDIRLRNWSLVLNNRTGDVLPLVGARDDTLEELLVRDTGQAEESVLDKLSIGLLGSIVLLIRAIWMTLRDPGYERRVVILPQDEVSRLCVQARSDLKMQGGKELFISEADVLAAWAARMVAASQPRPRPVTIASVINLRFTLDTLRETSGEYIHNLLQLAYVPIAPGHTTAPLGITALAHRQQVTEQCTKSQTLAYIRMQRDHTKATGDLKLMFGSPRAAFLKVNNLIRLDFFHNIDFSSAVIPSDDPGIGVGTRQNPAGTIVDYFTLSLNQATIFTSDPCVLGKDHCGRIQMLGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9J9</accession>
    <name>A0A9Q8P9J9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Protein farnesyltransferase subunit beta</fullName>
            <shortName evidence="9">FTase-beta</shortName>
            <ecNumber evidence="2 9">2.5.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06124</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11535"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:86019"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="2 9"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762503.1">
        <property type="nucleotide sequence ID" value="XM_047905272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9J9"/>
    <dbReference type="GeneID" id="71986002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06124"/>
    <dbReference type="OMA" id="WCIYWIL"/>
    <dbReference type="OrthoDB" id="10261146at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02893">
        <property type="entry name" value="FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000014">
        <property type="entry name" value="Protein farnesyltransferase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026872">
        <property type="entry name" value="FTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF6">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="123"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="55764" checksum="62C3ADB3A19B2D2C" modified="2023-09-13" version="1">MAAASKEQQHRPGDETEDTLDETLSEARIEELSSENSDEDYSDVTEDVIDAPPFPGNHLLKQQQIQQRLPQWLNPDTFNLFHTEVTTETSEKQTETTAECLPLLFGKETLAGIPTNSHGIPHLNRAKHITFLEGWLGGFPAPYVLMDASRPWIFYWCMAGLSFLGEDVSHYKERLITTVRPLQNPTGGFGGGHGQYSHCAGTYACLLALAAVGGLETVDRKAMWHFLGQVKQADGGFRMAVGAEEDIRGAYCAMTAITLLNLPLELPPDAPARKAGLEKFTDGLGEWVGRCQTYEGGISGAPTNEAHGAYAFCALACLSVIDAPHVSIPKYLDVDALLRWLSGIQTNPEGGFAGRTNKLVDACYSHWVGGCWSLIQAALFGKADAGKVKDCWSREGLIRYLLCCAQQPGKKGGMRDKPSCRPDAYHTCYSLAGLSAAQNHFLYDTKAPVQDDSTGRLEAGFNWTAVSASEGERTAWQFDEDDAVKPVHPVFVLPFDVVERTKAQFQKGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Q2</accession>
    <name>A0A9Q8P9Q2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762875.1">
        <property type="nucleotide sequence ID" value="XM_047906045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Q2"/>
    <dbReference type="GeneID" id="71986775"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06897"/>
    <dbReference type="OMA" id="RIVFMAG"/>
    <dbReference type="OrthoDB" id="3645602at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040310648" evidence="2">
        <location>
            <begin position="26"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="34847" checksum="10CE745FC3931361" modified="2023-09-13" version="1">MAHSKMLPAVIQAVILCGLSSIVSHHLVNNAFTNAGESELWLNITTAMARIENATTTGLNNTTISNTTTTPALNLTAEHLPSNSTQINPPGGESYYGQTLPRSMFILAMIAPLYYYWQLWLERILPRRARAEARLPPPEKADFGDDGDREQEVIEKWIAQGKIRRSSLSWWNTFLKWALHCTLGALWVEAMRYLLETVLYWRWPLTIWKKLSYWEILFRFAGTLFSTGPLSSLIGFILVPAHKRMVFESGADFFWSLFWGIALTTVLPLIASNSHVQYGVAMWIEGMENQTRNARAAPQFPRLGDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAB7</accession>
    <name>A0A9Q8PAB7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TBP-associated factor 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06709</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763148.1">
        <property type="nucleotide sequence ID" value="XM_047905857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAB7"/>
    <dbReference type="GeneID" id="71986587"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06709"/>
    <dbReference type="OMA" id="YFVQFIA"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000033">
        <property type="entry name" value="Transcription initiation factor TFIID complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000001">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="8">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00076308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="447" mass="48984" checksum="96B7BB076B7619DF" modified="2023-09-13" version="1">MSVWNPENVIDVAESVGIAALNRDVAEHLARDVEFRVHQLIEEALKFMRHAKRTTLTTQDISQALRVLDVEPLYGYESTRPLRFGEASIGPGQPLFYVEDEEVDFEKLINAPLPKVPREISFTAHWLAVEGVQPSIPQNPTQADQRNQELAAKGQGANTLAAVSGNDSVQVKPLVKHVLSQELQLYFEKICDAILDESNEQYRAAAFSSLQTDPGLHQLVPYFIQFVADKVTHNLKSLFILTQSMQLVAALLENPSLYIAPYVPPVVPSVLTCLVGKHLGPSHAGDIHFSLRDYASSLLSSIARKYGPSSSTLKPRIARSCLKHFLDSHKPLGTHYGAVLGLTMIAGGAGVRLLILPNLKAYDVHLSECMKDDAKRADAEKVVEAIMRALDELEKDAVTAPQANGHPEGNALKDKLAEAIGETIGSRVFESGRQTLINAVLEKDLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM2</accession>
    <name>A0A9Q8PBM2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_06819</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763856.1">
        <property type="nucleotide sequence ID" value="XM_047905967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71986697"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06819"/>
    <dbReference type="OMA" id="FEDIAWD"/>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="15">
        <location>
            <begin position="39"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="255"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="555"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="179"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="518"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="668"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1416"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="668"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1420"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="775"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="561"/>
            <end position="569"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO19490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1558" mass="174194" checksum="B7C5B38B5E2B815B" modified="2023-09-13" version="1">MAPKPPWNKKTTLHTNVQKATAAREAASPAINYGEVQDEEIAVLEAIYMDDYEEVAVKTAWSKTTDRSFKLKIRPGSDIAQPEEYVTLTVQLTATYPKSAPILDVQGLDKFHDRTQQRIQNVLRLRPKQMIGEVMIHAIATEIQDALEDAINSRAQGVLPSLDEERASAEEVAIGLAKEAEEAEARRQQEEQEEEDRVLKQMVSKELTRQEKRKSIKPSKDASSQAHEVTSAETVVFDQHGRVKVGNDPESFAEVTIINLISSTSRTSTFEGIPVISGVSRPPKVAIVRRKVERPRSEIFQLEAALETARKLDHVSLVALLAFRVDKINNHNSELVLCQDWVDGKSLFHMLSLSGMPFGVSKAKQYTTQLLEGLDFVHSNGLVHGGINAHIIFFSSTPTLAPKLADFGYAAFLSHGDESIPMKWRFPDSGSVSTSTQRQRDIWDLGIVIVQMLLGLDALIDFTSPASLISRLDLSEALEDFLNKVFTDKKRSSCFDLLPAEFLRTDTPILQEMAAPPLRGHRTRKSSSGFSSPYRRSRHNSSNVHEPYSRYANDFTDLGRLGKGGFGEVVKARNKLDGGVYAVKKIRQMPHLLEQVLKEVVLLNRLNHPYVVRYYSTWVENDLQDTLVEDAISSTEDTLSEGPNIDFGYPSTGGLDFVSSSGYQGIEFGDDDDDDDASASDDDPFERGSAVTGNGNSTAESEETSQAENLRLNKTRSDSRRNLMSTLYIQMELCDRRSLRDLIRKGLSDDEAWRLLRQITEGLSHVHEHHIIHRDLKPDNVFIDAAGNPKLGDFGLATPGQQFAVEKPSGSKGQGSVDMTRSIGTAMYVAPELQSSSGTNYDSKVDMFSLGIMFFEMCQAFSTAMERINELIRIRQKEHDLPSAFQITGEKSTQGRLINRLISHKPSERPKASELLHSDMLPLKVEDETIRQALLGLKDERSPYHQQLMSALFAHDSASSQRVKARAWEEKAPTTAEDANRVRLRNIARLSLENVFRRYGAEESRRDSIFPRSGIYAAANVVQLLDSSGNLLQLPFDMTLPYAQQLARQPASIRCNFTFGGAFRDSFTGGPPRVSEEVDFDIVNVGKDEDIAANDAEIVKVMDDIILDLPTFDSVPGIVLHLNHGKLLDAILDHCRVPIALQHVVKEALSKLGVHQITWAKLRPELRTIGLSDTTLDDLQQFDWRAAPEQAMNRLKSLLEATTSRIQAKSDEATQHLRRILAYLKTFGIIRKLYIAPLSAVNAKFYESGMLLQCLLERKKNSVVLAAGGRYDSLVRAHRVSETSSVRQGAVGLCIGIDTIVAHMMKVCAPGSKSTFLKDPGQNNQLAKRCDVCVVAEGTDQLRDAGRRLVFSLRANFVSAELYHPSFPDQNCNFIVSMRHETSPTVRVSSTTSTGEDTDVAINFLIPHIQQELREQANSKARRPLLRHHSSHQDSDRKGNNVQVLMARHGSKKSNKYGIVESVEQNWSDKLEKLKSVPKLAIETRDEVLDLIKKTRLSDGESWRKCIQSVQLSERQYVQQVQEMLEAWRKTWEGGEGVEEVCVSNFRTGNCVYYDLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC94</accession>
    <name>A0A9Q8PC94_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High-affinity fructose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10568</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764184.1">
        <property type="nucleotide sequence ID" value="XM_047909716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC94"/>
    <dbReference type="GeneID" id="71990446"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10568"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="250" mass="27940" checksum="7D9E2D31D133BEC8" modified="2023-09-13" version="1">MLLYSVLVEAYVRWHGSLILGTIPTFLCQNDQVLDACKPGKDANSGHKQILDIDNNINKTRHCQRTAATVHPTKTRRPLHISLLPSVPSRLQPTMGPLKRTAKAPQPDANADGETPASPPPPIPHAPSAAHLALTTERETTSDAYKKAQKAEKQHRTRRQAARARTHYAAAKIHIKTAYKEFVSGVEASIGVVGLLHYVLREKMSASPEDKQTRKLERTASKRQKLEEKMRKIEDEDRMARDAEKETPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="7 8">
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                <person name="Stergiopoulos I."/>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="OMA" id="FYHYPYT"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mae1"/>
    </dbReference>
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        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF3">
        <property type="entry name" value="TRANSPORTER_MALIC ACID TRANSPORT PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="447"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="547" mass="61000" checksum="AFF8C95A3B509C37" modified="2023-09-13" version="1">MAAVDRLHLPAERSDRGKHDRHASLRHLPNGLTSSNGNLTSRPPSVNGEKGSSDVPGTLRPTRPSMHRNWSAQNMRHNISLEHLHVDLHFKERIKHFTWTWFTMTMATGGVANVLYQVPYRFHGLYAIGCIFFIFNMVLFLFNVTMISLRFYHYPHTFMHSILHPTESLFIPASLISIGTILINVSQYGVSQPSTGEWLLSTMVVLFWVFCGLAVCFSAGIYLVMWSTQTFTVAQMTPIWIFPCYPLLVIGPHAGTLAKHLVNRPTDALTMILGGFVFQGIGFLLSLMIYAAFIYRLMTEKLPQENLRPGMFVSVGPSGFTISGVVSMGLLLPSVVTKDFLLKGNGELAAQVSQIASIWFGLWLWGLALWFFIISVGAHYSCVRKGRMTFAMTFYSYVFPQTALTTATFAIAEALDNKPIAILGCVMTCLVIVVWFAVFILMVRAVIEKDILWPQRQEDRAEGGWQTHSARPSACNGRTGSPISIRLRSATLTGADQAQPIDNNIEEPCRPNAKASGQDNTLMNMTVPVENPFEAERNKITGPDEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCZ6</accession>
    <name>A0A9Q8PCZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764554.1">
        <property type="nucleotide sequence ID" value="XM_047909871.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990601"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10723"/>
    <dbReference type="OMA" id="MGLFNKP"/>
    <dbReference type="OrthoDB" id="5335210at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1161"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="316"/>
        </location>
    </feature>
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        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
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        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
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        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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            <end position="844"/>
        </location>
    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="1013"/>
            <end position="1023"/>
        </location>
    </feature>
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        <location>
            <begin position="1099"/>
            <end position="1126"/>
        </location>
    </feature>
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        <location>
            <begin position="1179"/>
            <end position="1190"/>
        </location>
    </feature>
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        <location>
            <begin position="1192"/>
            <end position="1203"/>
        </location>
    </feature>
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        <location>
            <begin position="1204"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1285" mass="138151" checksum="6DE24059A4B74088" modified="2023-09-13" version="1">MSKLFSKKKANNDATLSNEQALNALSQPASPTLNKKSSSSRWKKSKKPQPEAKPQLDLSAALPSTDDFRTSLLMPSLSTRFSMLREQDDPNSLIGKASDDSVLQPRRKSRMMNDFGFASTALGDIAEVSSIQGSVRPPFTRSSRENSYVSDDGGYGSEADATQSVMSRSRPGEGNVLFGGRQKVYKIPNSGATSTRSLGKLVYEDDVGMSAFQKYRHREREFDESQLPRPSDESQGFNFGLEGSHDGLDTLPNDSAKDLSHSPSLSSYEKKRSTTSSMARSDARSSTAATSIASQQAVSAQPSPGHAPAGAATAATSSTAANVAPITMSAPLLERPNPKARRLYDQGLDQHMHEQQSSAITRLNSIQKQRTIGGMKSPPFLQGAKSTGNLNDRSTEPFTAFRGQSPPPTAPLPALTTLGSFRHPQSGSSSPAPSGPASPIDAPNNVLTQALEPADRGKATAMGAFNKPAHAFDENQYLERQKALQRSNSSAVMKKSGSISAAKPRTERSEYNGNQSPDLFARSRTPSDAPSHHEMTKKAYNMFQNAANHLPAPSADQRSDSPAKSPPLPDTHRTFFGNISASDDEDDGEEERIAQSFDQPEYGYGNYQTRWQPTPLQSVSEHPSTQNDRWKTTLVEEEDEFDVKPLAPKASASSLRINAPAASFQIPQPLDSPTLGPQAQALNGMVHHLRQRSNNSSIYPTEEVAQQEDEEEVPEVPELPWTTKKSDSFNRVANTTPEAQSARESTYAVSNPWDLDEQSAGASRASRASEAVSTVDRSSNALSPVGQSLMAQFSPVERTSSPRFPSTSRQPSVVQDSSSRFAHPTARDSEASFSNENSVPTWQQELHKQHTRDASTATQQEREAFQSELAARRAAIQEGLKQKVEWEAHSRGTSPAPGAMRAFGMLRSKTSRESFVHAQDQPQKGVRALGINGASSTSLVDSVRPRGNSSPRPPLPNAQHPAFKQDGPGPSTRDADTVQGARELASSRGPASRARSRSNSTATTGRSRSRTGPYRDDLEKAMIEGHGTSAAAHTPDVSPFPGASPAIGSDGTGRQSDEDRRNAANYFEARAAPANKGPSPNGLTPTVYTPGRPVPVANPYSQNHTPALNGTSPSIELSHSPITPSSARPGGLRKITISKADISEPKLISSTSNVDTVDLPPGASLKNGMEDAPPIPPIKPKRRGTRKLFSRNRSDSTGDHEIKATSSDPSLNTSPKREFQFPPSNVVRMPAIVSPQDFHSSPAVPQVGFVTPGSPERVQRSTSTTTAPKRSVTAPLSAPLDGSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE29</accession>
    <name>A0A9Q8PE29_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11438</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765115.1">
        <property type="nucleotide sequence ID" value="XM_047910586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE29"/>
    <dbReference type="GeneID" id="71991316"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11438"/>
    <dbReference type="OrthoDB" id="3649438at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="2"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="25707" checksum="BC47137A093C5AA3" modified="2023-09-13" version="1">MAIKASIALMLLRLLVDVTQRTILLVVLAVTELYSAAFFLLFIFQCSPVSFFWTRFAGAEGFCLNTSAVTGAVYAYSAIMCVADWTFSILPFIIVWNLEQLPKREKAMVGVILAMSAIASIATIARIPYIHTLANQDDFLYVTTDVAIWSCTETGLAITACCCATLRPLFRHLLDQARTKFSSSRTSGRGLNRRTRSWQPLPAHRRGSASVSTEAIHLSPDLKGGKSGQQYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE83</accession>
    <name>A0A9Q8PE83_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_11029</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765214.1">
        <property type="nucleotide sequence ID" value="XM_047910177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE83"/>
    <dbReference type="GeneID" id="71990907"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11029"/>
    <dbReference type="OMA" id="MKVYPLY"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17973">
        <property type="entry name" value="DEXHc_DHX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000324">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000003">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044756">
        <property type="entry name" value="DHX15_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="113"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="300"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00055599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO20848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="771" mass="86807" checksum="C4DA2683994E7BAD" modified="2023-09-13" version="1">MADSEQPKKSRFKRQKTNDHRSDDKANPYLAHMNFDNEAGVGLNGGANGKSNGSYNGTDLSKWPRYGTTAKMAAQAEDGPDNPFTGVPLSDRYFGILKSRRDLPVHAQRQDFLDMYQKSQILVFVGETGSGKTTQIPQFVLYDDLPQTQGKMVACTQPRRVAAMSVAQRVAQEMDVELGGEVGYSIRFEDKTSPKTILKYMTDGMLLREAMNDHDMKRYSTIILDEAHERTLATDILMGLLKEVVARRPDLKIIIMSATLDAQKFQKYFNNAPLLAVPGRTHPVEIFYTPEPERDYLEAALRTVLQIHASEPEGDILLFLTGEEEIEDAARKISMEADEMIREADAGPLKVYPLYGTLPPAQQQRIFDPAPPPYKPGGRPGRKCIISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEGAFKKELIDQSYPEILRSNLASTVLELKKLGIDDLVHFDLMDPPAPETLMRALEELNYLACLDDEGELTTLGKLASEFPLDPALAVMLISSPEFYCSNEILSLTALLSVPQLFNRPAAQRKRADEMKNSFAHADGDHLTMLNVYHAFKSPAAQENPKQWTHDHFLSFRALQQADNVRLQLKRIMEREEVELISTPFDHKDYYINIRRALVAGFFMQVAKKDTSGKTYVTVKDNQSVLLHPSTVLGQDSEWVVYNEFVLTSKNYIRSVTAVKPEWLLEISPNYYDVDSFQKGEVQTSLRRTAQKMQRRSEINGKAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG95</accession>
    <name>A0A9Q8PG95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sequence orphan</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766311.1">
        <property type="nucleotide sequence ID" value="XM_047908633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG95"/>
    <dbReference type="GeneID" id="71989363"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09485"/>
    <dbReference type="OMA" id="WFASKPF"/>
    <dbReference type="OrthoDB" id="275936at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038781">
        <property type="entry name" value="C365.16-ike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37845:SF1">
        <property type="entry name" value="SEQUENCE ORPHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="30820" checksum="73CBAAC986B6CCE7" modified="2023-09-13" version="1">MEQKQLASKSESNHGGSAVQTTAAPQLRSESQSQDLVKRFAVDGLAALTAAIAVSPVMVVIDRAVTEAAAGQRSFLGSANACLADAAKRPQTWFASKPFAAMMLLYLGTYTTANAIDTVSAHAEGLPASTTTSTSTKVAAVTTTNVGLALYKDATFARTFGTTRLTRGLPAVSCAPFILRDGITLFATFNLPAIVAPMLPERFEGVISRMSVAQLAMPMASQYFCTPLHLLGLDLYYRLGKLGVGERMKAIRPTWLTASNARALRVLPAYGLGGVLNNDVRKWLMERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGC1</accession>
    <name>A0A9Q8PGC1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766460.1">
        <property type="nucleotide sequence ID" value="XM_047908374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGC1"/>
    <dbReference type="GeneID" id="71989104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09226"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="110" mass="12212" checksum="4F2C54ABACD06832" modified="2023-09-13" version="1">MPHRAMDEQRRALAEEGLKYSAVAPLVEAIWSKYGYGTKGWDPDGCVKHFKTVLELMQKNSIFATVVASGDHVAEIVKNPEDYSQALIDLAKELSDPDMGQDDAKDVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGV8</accession>
    <name>A0A9Q8PGV8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Propionyl-CoA carboxylase, carboxyltransferase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </evidence>
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        <source>
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    <sequence length="593" mass="65290" checksum="AFCFD517529104F2" modified="2023-09-13" version="1">MANGEDTQSPSSKTDAPHTKAAARAEQVSGHLKTDDQTQKSNTGRRRRKDKKDELPADYSDILGHLSTLRQISNTPDTSRRGYVRQIQDGKLWVRERLDKLLDAGSFKEIGSVSGHVKWKHLGGEREEPESYLPHNNVQAFGKLNGRQVVLTADDFTIRAGHQDGHLMAKTLFTEKMSIQLKLPMIKLTDGSSGGGSVTSIAATGFSYVPPMQQGFDVVTKQLNMGIPNLGAVVGPAIGLGAARVVSCHFSVMAANVGALFNAGPNVVKNATFEEGLSFTDLGGPAMHCTNGTIDNMAATEEECFEQLRTVLGYLPNCGTQVPPVVSCDDPTDREDVELQTIIPRKRERMYNPRKVITGVVDKGSWFEIGALWGRTTIIGLARLGGRPVGILSNNAEVLSGAIDAAGSQKLTRHLKFCDVFNLPILQFIDAPGYAVGTVAERTATMRWGVELTKAYYTTTVPIFSVIIRKCYGVAGGVMVDCREPHMRVAWPSGEWGSLPLDGGIEVAHSHELRQIEKEKGEEARKERYRELDEMYRRMMNPVRTANHFSIEEIIDPVHTRSLVAEWLRLTYEADLPERVVHRMGGKLQPLYA</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </reference>
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    <dbReference type="GeneID" id="71991648"/>
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        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
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        <location>
            <begin position="266"/>
            <end position="306"/>
        </location>
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        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="359" mass="40620" checksum="BD180BBDE8001911" modified="2023-09-13" version="1">MTNQRELRRSIRPPSTIAIPKICALNGMMVCHRFYEEAASTWFRVRSIECSDFDHGNLIRASKLIQRNIVSFGFEWQRRLDRCAELKLCAKLRKLRIVVSDRVFDMFEDRLCFVHDFKDDDFFTMKMVQDILDIATIERVEVVPAEPNVISLAQTDEEVAQWHKNVTALQTCVNREIDRVWEEEEAYIENQGYQPEEIVKAPVENSLSDKAVRKLCKSVKKAAKKLDGSTKASTSGKVTLVVKEAKKVQGSTSSTEVLLSGSRDKMSENINHSGKHGMIDIDLSRSPEGPVDNRESGETHDGTPNMTIHEPAKVLAQKQMLQDLSIQDSHYSVVLCFAALMLICSISNSVSLWVLASKL</sequence>
</entry>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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            <dbReference type="EMBL" id="UJO22910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="37369" checksum="0F83455C1A2CDA05" modified="2023-09-13" version="1">MRVVDKPQHGPHGRTAGLRLRLAQDPTAPLPGFRCVFWNLPLELRNMIHELVWQGKRVSTGLLEASKDETSPSDGPHKASLANHSRLDGVAIHLSDLAVSKEFCQEVRYWLLEHGTVVFNDPTVDRVHIDRALWNGKFDQALQHIRSIEVSAGSLFYSSLLWSLKLPNLQRIKVTDCDAWRLGVAVRMRRSMGTSDFNEDCGSLQRFRNLGDCLFIRQLQRHTKLRYIKLAIPPCENCEDVFRACPDSEVEATCHLSGTLALSMEAYVLSSVLGNVRVEISAERKQVCQLNEEIGARTQIVTHIVGEVIAYDDQDEINSMAETLWPTSWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ70</accession>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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    </dbReference>
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        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="36376" checksum="B919427028D9A8D0" modified="2023-09-13" version="1">MAHINRINTERLRPDGDFEYRIGTSRHFQHAKTRDVTDKQVQEYRERMIDEPKTWERDFEVERIAGHDEHDCLVIFKPHYRTGLEVRPGWFRHNVLSNDLIQAYKDFVAETDKEYAAAKEEQGVQTAQASSKVARLIQGAFQAQVMKPVGAKLREVVLERYPDAFRIQDAMDGRDATAQDGNDEAAANSRDRQKSEEPTVPFYEMTTGIVGEDSTHYLFLNTGGSARWVQKTYMSEEWTGPYKMQKEQLIRAFQGHTGGQVDYQGSWRPDLHLHGMFPAFLVLPSPISAEVREEVEKRYPGLLHEEGASDDASTMAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJF7</accession>
    <name>A0A9Q8PJF7_PASFU</name>
    <protein>
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        </recommendedName>
    </protein>
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        <name evidence="9" type="ORF">CLAFUR5_13318</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="9">Race5_Kim</strain>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768140.1">
        <property type="nucleotide sequence ID" value="XM_047912466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJF7"/>
    <dbReference type="GeneID" id="71993196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13318"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620:SF7">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040207497" description="glycerophosphodiester phosphodiesterase" evidence="7">
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            <begin position="18"/>
            <end position="448"/>
        </location>
    </feature>
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        <location>
            <begin position="89"/>
            <end position="418"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO23774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="49081" checksum="387CB4D811BEA502" modified="2023-09-13" version="1">MSSFTLLAAALLTTAHALPAPADHGNYGKYGSYGSYGAKPDNGSSSEQPTEKYVVSLGPRPYYLVNNMTDGALKTKLDSCKSLDFSVTGFTIGHRGGGTLQFPEETAQSEDAGARMGAGILECDVSFTKDRGLVCRHSLCDLHTTTDILTRPELAKKCVVPFTPANATSPANAVCCTSDITIAEYETLCGKQDAFNASATTPKEYLGTAPDWRTELYDTCGKLLTLDSYIDLVESQPVQRNFTPELKTPPTPYVPMPFNGYTQEQYAQDLVDTFKNRSISYDRIWPQSFLYDDILYWLKNDHEFGKQAIFLQEYDTAADIANATRNLTEVRAAGVNIIGPSIPMLVTPGGPDNKTIVPSAYAKAILVEGFDIIAWTYERSGPVATVKESGEYYFSSIADIVSYDGQYYDLLDVLANQIGIKAMFSDWASSVTYFANCFGLEGPRNVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK87</accession>
    <name>A0A9Q8PK87_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450 monooxygenase lcsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13277</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO24030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK87"/>
    <dbReference type="GeneID" id="71993155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13277"/>
    <dbReference type="OMA" id="WMEMRMA"/>
    <dbReference type="OrthoDB" id="6692864at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF112">
        <property type="entry name" value="L-ORNITHINE-N5-MONOOXYGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EP450IV"/>
    </dbReference>
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        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO24030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="62479" checksum="DDD60ABEFC10CC7F" modified="2023-09-13" version="1">MMAVMYEDSMSSSQTALSIALGGVVVHTVYFQRYEYHRHLYSLLGISFAITAFYPYFLYRWLAKSPADSIYIATFHGGSLVGGAVLSTILYRLFLSPLNRFPGPFSARLTDFWLAFHVGKKLNQYQRLQDLHRRYGRIVRTGATHLSISDPTFVEPVLGYNATTVKGAWYDIDYPHHSLHEERDPAKHEAKRRLWAPAFSVSALRSYDREIQPVNRKFVQRITELEGVPMNITYWISIHMFLVMQATVFGKHDALTGSGEAAAMVEVLSSGMEILGLVLPPWFIRLLKLIPGNPLADFHAFTNRELENAVRSNFYLGKDADHPSSRSMVSWLHRIYEHEPDPATNALFRVDARLLITAGSETSASAMIYLFYLLAKHPDHVLIIREELGACIQGVESWSDVDINSCKHLNACIKEALRLFPPGPSGVFRLTPPQGLQVGEIYIPGNTNIQLPTFSVHRDASAYVQAEAFIPERWYSKPELIKNINAWVPFAHGPYQCIGKSLAMMEIRSLTAKVLLAHDVRLAPGEDGSLLLNESKDHFSMSLAPLNLVFNRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKR7</accession>
    <name>A0A9Q8PKR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768550.1">
        <property type="nucleotide sequence ID" value="XM_047913133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKR7"/>
    <dbReference type="GeneID" id="71993863"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13985"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="636" mass="71603" checksum="356A89B3C4C088EC" modified="2023-09-13" version="1">MFSRYLGWFHPSEQPVSTSGYGLDNRDERLLPSKRDQAIAEIYRLAKDQEPSISRDSQCHEPAARDSDNVGPEQSSYKDKAVECTTTKRTGDGQTPSPVRSELADRYISRSSDLPDIEAGSQWFIEAKNGDYGHDQLSLELNRPKAHAHWQSNYDMEKLGRLALRGQRPVEEKSFPRKSRHPDDTEVVLDSSPSMRLETGPQLMAKGGGKQKKTELTCSKSKAAIVGGCMALRDQAAITAQMNLRKHRNTKFQTQPDGSSAQQVTNDGDTNNGRRPKQRVPDFSKLSTRDREQYVADMATRQNEAQAALDRKYERIWKGYTKPWEIVREKRSKAADEMIRAAKAQAKTKPASKTQGPYILGSTSASTFDEDNPSDNKKAEVDDKGVEAVTKEAESLQSDECSLQPDTARDRPSHASRRDVAAPRSPPEPRHDSREVREAPQQDLPRSHTPASVIKGKGVAKLSARFEVADKPATAANDEPGKRQARNPNASQHDARITAAGINARLERAKAARKAAEKARRPNVETPKADAEPEKEPPKREWRKSNPALDGDSLAVRYAQLDAAKILELDRDESRRLFKLKQEQLRRERDEKWWEQKEKKEDDVSTAERYRQRMVRAKATKSRLQFEADSAEFGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKT5</accession>
    <name>A0A9Q8PKT5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_13391</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768626.1">
        <property type="nucleotide sequence ID" value="XM_047912539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKT5"/>
    <dbReference type="GeneID" id="71993269"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13391"/>
    <dbReference type="OMA" id="GNTTMYQ"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="229"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO24260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="390" mass="43984" checksum="2C64D5B8DB341F60" modified="2023-09-13" version="1">MAISRPRRAARWAQTPATERRDLAHVQRWERAKRDESHPSRSFAPYNVGVDVPQYDADVYEKHLISEGWTKEETDYLVETYRECNGKWPVVADHYAYEGSERSMEDMKARYYTISAALLALATPISSMTAADYTQYETLSNFKPEQETSRKRLAEGHLYRRANEVDEESVLLGELQRIMLNQATLDSQREDLRKRLDHPSPNTNSYQYNTSQALTGLWQQLLAQDRLKKNPRLRPTGNPAYDGLPGTAPISARPRDSLTAQASDPNTLPARRPTRDSLPSATPQSALPTDLSKSDMSRFGVIHTTDKLPSGISFASDKLSKPRIAKSTIQTEKIAAILQNVGVQDLIPLPTGSVIEVFEGIMGKVQTLLDMRKLAEKEEQEIKIRDAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL26</accession>
    <name>A0A9Q8PL26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768757.1">
        <property type="nucleotide sequence ID" value="XM_047913159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL26"/>
    <dbReference type="GeneID" id="71993889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14011"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17462" checksum="04BD22D9A5781F8C" modified="2023-09-13" version="1">MTSSIPSSANNIAIPHKEAHMAGRHDLQTGYPVAFKDAQRYGGPGMTPEEAAIEHDKIAYHDRLKTGPKASTEQACKYRPASASSTLSSDVRHMEDLEYEKALEDGEVKEIEAPANAPEQIQKPPRDLTVRFDPPSENSMEWARGHYTRRFPSIDGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLT1</accession>
    <name>A0A9Q8PLT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769194.1">
        <property type="nucleotide sequence ID" value="XM_047912856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLT1"/>
    <dbReference type="GeneID" id="71993586"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13708"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="78" mass="8490" checksum="F3366D05C96F4783" modified="2023-09-13" version="1">MSGNGVTGNDWFIGGVLIPNNQVVRRDPGYVPGHTLIGGANAPFNTYPYWPGWHAAGFTMSGNAFAYPRSYPGQFRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMC5</accession>
    <name>A0A9Q8PMC5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769393.1">
        <property type="nucleotide sequence ID" value="XM_047913363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMC5"/>
    <dbReference type="GeneID" id="71994093"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14215"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040213478" evidence="1">
        <location>
            <begin position="19"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="37980" checksum="8C3DA65BF31F86EE" modified="2023-09-13" version="1">MLQSGITALAFMAVAAVAAPASTVGGPPVVYQTAPNAPLVTATTLAAPAATAGSKVKRQAATCYPQPSGISHRSTPDNAAAFRSDSYYANAANAAKTPIGFNSVFTNTGASPNADQYLGYTLMDTYDVQTCANKCNAITGCKSFNVYFERDPSVDPNDASCLNPPSVTNIKCVWWGSTISTQNNVNTGQYRGQFEVAIVGSNGYTGTPTQRGFRIKTGNSGTVMDNRWLAVSPGEGAAVALNPQAYKGQTSTFQFGPNGELLQTYYATGMAGVAPNVQGNWDFLQYRKVGQTGVDYIKCSAGDGGNGSLIVCQSKSGFQYAGVCPNRKQSISGLLHFGLPKKTPSDCHWIGLYIDTDISGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMQ0</accession>
    <name>A0A9Q8PMQ0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_14525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769746.1">
        <property type="nucleotide sequence ID" value="XM_047913673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMQ0"/>
    <dbReference type="GeneID" id="71994403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14525"/>
    <dbReference type="OrthoDB" id="18915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO25380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="609" mass="67667" checksum="6C9A8759B7C3489E" modified="2023-09-13" version="1">MMNHRQPVATASSYYHHHAAGHHHHPAAASFPPHSQHYHETAHGPLVYRPLQLPLAAPSPPVPVPVQQQQHHQQSQHHHLPQHSVEQPAQLPLAAVGAGPYQHPTFRHHSVATLSHRTRAQTRQHQRSAMADYQGHHQATDEELAQMQELSAKYEPEVTGPLVGQRQPSTAITTEYASADPIYQAKTTTLPQKYSHYRTVRGDGKCGWRAVAFGYFEALIHNGDTNTIMFEMGRLESMKNVIVTAGFDPMLVEEFADEFRDLLRSINETMQQGGNAIEVVENAFNDDMQQNYIITHLRTATSAWMKTRDEYAPWLLGQTVEEYCKLQIEPIGAEIDHVGLVALKDALLSPAGISLEVMYLDRSEGSEVTMHRFDPVNHGGYTIGSVRLLYRPGHYDLLYKPEDLPAPPPPPPAPVPTYLQFATQAYEPVQDLGVSEWMTSIPGMSYANMSQGSSWSSSNFGSGADFFSTPAPVPSCAPAVPTPPAPAPQPHVQSQPMYVSASTPTQMVTPPTQMSHELAIRTTVPQHTLGHPDFQHQLSGGPFRPSAWQLEENFVQASSMPFQTSIFRNSHFNTAHFLNPEFQPEQWDPDDEYAVVASSTKAPRHKNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQL2</accession>
    <name>A0A9Q8UQL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Abhydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763245.1">
        <property type="nucleotide sequence ID" value="XM_047906801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQL2"/>
    <dbReference type="GeneID" id="71987531"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07653"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000039">
        <property type="entry name" value="Esterase ybfF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="51"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="33967" checksum="7D62F56C81F95DAE" modified="2023-09-13" version="1">MLARRALLRLQQPLRQCATRRPFSTTELSNGIKMAYELWEPEKGQEPQGAPIVFLHGLFGSKRNHRAISKALVRDLKRPIYAVDTRNHGDSSHDPRHDYEALAEDLELFIDSNKIEDSTLIGHSMGAKAVMTVALRKRVPIGNLIPVDNAPVDAALKSDFGKYCIGMRKIEEAGVKSLKDADTILADYEESLPIRQFLLTNLMRAEDGTQKFKVPLKYLTDSLNKLGDFPFKDPHQARWEGPTLFTRGTKSHYISDEMLPVCGRFFPNFELADVDSGHWVISEKPDDFRQAVVDFLSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQS8</accession>
    <name>A0A9Q8UQS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L4-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763352.1">
        <property type="nucleotide sequence ID" value="XM_047906346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQS8"/>
    <dbReference type="GeneID" id="71987076"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07198"/>
    <dbReference type="OMA" id="ALYGTWR"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="280"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="371" mass="39789" checksum="304563F3DC4F5B2B" modified="2023-09-13" version="1">MASRPTVTVHGADGAASKDTLTLPAVFKAPIRSDIVQQVHTGMAKNKRQPYAVSEKAGHQTSAESWGTGRAVARIPRVSGGGTHRAGQAAYGNMCRSGRMFAPTKVWRKWHQKINLGQKRFATASAIAATSSAALLLARGHHVSTVPEVPLVVSSSAFAGGAIKKTSAAVGLLKAVGADADVQKVKNSRKLRAGKGKLRNRRHQQRRGPLVIYEPEKDGKDIVTAFRNIAGVETCSVYALNLLQLAPGGHLGRFVIWTSSAFSALDTVYGSTTTPSELKKDFLLPSNVVSQPDIAKLINSSEVQSVLRPVKGGAVSKRTVVQKKNPLKNKQVLLRLNPYAKAYSKEGLGHVKADDKVIEKEKAFEATLHEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR38</accession>
    <name>A0A9Q8UR38_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763683.1">
        <property type="nucleotide sequence ID" value="XM_047906536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR38"/>
    <dbReference type="GeneID" id="71987266"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07388"/>
    <dbReference type="OrthoDB" id="3650798at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="29320" checksum="A7F56F478071BB59" modified="2023-09-13" version="1">MNEIPIGVSAEMAREPHEKRLDWPSKITAESAKSATKLFDTVELMEYILLQLSASDVLTAMGAVRSMHDTLIGSTKVQKHIGLLPDPSSEFRMPTMPLYYTPNSSSPRPFQIFYGLYFHDDLGTFKNLSVATRVLRTEAYDRDHIAAFSFEVYHEGPFLQKLGPRVQKMLPFQPPVTEVEVCLRCENCVPGLWPPPGSRSPEWWYPTTIKPRDGKFITFGDLQRAAVCKRTEHRKLCTKPRARSTVDLRMCGEVQISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URF5</accession>
    <name>A0A9Q8URF5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit tim16</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">Presequence translocated-associated motor subunit PAM16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_10336</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM16/PAM16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764027.1">
        <property type="nucleotide sequence ID" value="XM_047909484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URF5"/>
    <dbReference type="GeneID" id="71990214"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10336"/>
    <dbReference type="OrthoDB" id="10262892at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000006">
        <property type="entry name" value="Import inner membrane translocase subunit TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005341">
        <property type="entry name" value="Tim16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388">
        <property type="entry name" value="MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03656">
        <property type="entry name" value="Pam16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO19661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="15261" checksum="FCE137C9AD6A3DDF" modified="2023-09-13" version="1">MAHRIISQVVLTGARVFGRAFAEAYKQASASQKYAASQAGNPTAANTLSSSGLTLSEACQILNVSPPKSGQADVQKIHAQFKRLFDMNDPKKGGSFYLQSKVLRARERIELEVREAQAAKEREEEIRHGWRPKLYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URH6</accession>
    <name>A0A9Q8URH6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764101.1">
        <property type="nucleotide sequence ID" value="XM_047909049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URH6"/>
    <dbReference type="GeneID" id="71989779"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09901"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="193" mass="20823" checksum="B83C9BEF46AFAAF0" modified="2023-09-13" version="1">MAPYGFVLYHGVWIDPDSLPKKGAERNIGDYRTWKDWKLLRELEQRGLPLPDPQTKGNMAKVLRKHDEDEEVFGPGPLSNLTTPANSPSKTGKDKAPVLSKPKSIPTVPTATDVPPARAPEQDIIDGNDSDTELETAGGGSSISGARRRLGRPSLAGPTTATAITGIENVPNVDYDEEVDGLIIPVISDDEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URI4</accession>
    <name>A0A9Q8URI4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764205.1">
        <property type="nucleotide sequence ID" value="XM_047909393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URI4"/>
    <dbReference type="GeneID" id="71990123"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10245"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046">
        <property type="entry name" value="GDP-MANNOSE MANNOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43046:SF12">
        <property type="entry name" value="GDP-MANNOSE MANNOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="21742" checksum="68CF46D145F94A15" modified="2023-09-13" version="1">MAEANTVLEARLSTKLEQLPPGYRYVVGGAIFRQHEGRIRRSRPELLLLRRAPSETLPGNWEIPGGKMEAGETIREALCREVFEETGLEVKSVVQRLLDVHWFHKDSGDRWVQMGFLVTVESTEEVRLDPEEHDDWMWSSKDGAERLPHLSGQAQLWEAAFRAQAGLEVVSPRHDDTAGPLIYVVRAVDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URL9</accession>
    <name>A0A9Q8URL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxynaphthalene reductase-like protein Arp2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764222.1">
        <property type="nucleotide sequence ID" value="XM_047909216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URL9"/>
    <dbReference type="GeneID" id="71989946"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10068"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009385">
        <property type="entry name" value="PRK12744.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="22649" checksum="1FA9774098EE1084" modified="2023-09-13" version="1">MSLSGKVALVTGGGKNLGADTARQLAKEGATLAIHYNSAKSKAETEAFVAALQKDGTKASIHVGDLTSAAAAEKLFSEVTQQHGKVDIMVSTVGMALKKPIVEISKAEYDVMFAVNSKAAFFLLKEAAKHIQEGGKIVTVVTALLGAFTGFYTSYAGSKAPVEHFTRGVAKELADKKISVNCIAPGPMDTPFFYPQETPEAVAFHKTQARARAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URQ1</accession>
    <name>A0A9Q8URQ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764339.1">
        <property type="nucleotide sequence ID" value="XM_047909751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URQ1"/>
    <dbReference type="GeneID" id="71990481"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10603"/>
    <dbReference type="OMA" id="WNFAIEL"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="28502" checksum="842839562BE7AD0B" modified="2023-09-13" version="1">MVLHWNHASSPRLEDDKTPLIQRDSTSAMAAPNMITIETRRMILRAAEQEDAIALHQIMSDAETMRFWSELPHADLARTKAWVSSMLRSTQNGVTDFMICLKSDIGGVLTIPERARPRIIGKVGIFRARPSHEIGFVLDRSYWGKDLATEALTTLLAYLFSLKKGYVVDTALNTTGLDPHVNLSDEELRSPWMYPAITADTEPRNAASIGLLKKLGFVETGRVERSFRLGDEWQDTLYLRLTREKWLDEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US86</accession>
    <name>A0A9Q8US86_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764955.1">
        <property type="nucleotide sequence ID" value="XM_047909959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US86"/>
    <dbReference type="GeneID" id="71990689"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10811"/>
    <dbReference type="OrthoDB" id="3916736at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="23"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="31221" checksum="D9D42E8DB655D108" modified="2023-09-13" version="1">MLATRPTSNSYSQSAFNNTATDPDIEITCSSYMWKCHKLILRNASEWFQRAFASGFQEGTAHTINLREDLSEPEDAIEAMLRFCYSTDYKQLEPATFKVRVFSLAEKYFVKGLDLLAIDKFLASVGKGTPVPDLTKAISEAYAICVDSERLLKDAIIKHVSEQADFLINFSGEKEEYNELMESTPGFAADVTRVLAKQMQATRKRRAESPPPESSSRARPVSDRAGRYRYACPDGCGTARTFIFTNLNQTASIQCPVTTRFYHLTGWEWQRYYLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US95</accession>
    <name>A0A9Q8US95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11516</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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            <authorList>
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        <text evidence="8">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
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    </evidence>
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</entry>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE4</accession>
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    </reference>
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        <source>
            <dbReference type="EMBL" id="UJO20696.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="22418" checksum="37E66C909255387A" modified="2023-09-13" version="1">MVVTNTAVSDIKNLLEVSTAIRAKVAANMAYLLIHSARQEYSRLERTAFALKNFPADLFEATKIYAENLRLPSRSQNSAFIFHQWQDPAWMYDFAALYLTHHKIFAVPLSFFMSDTSILANHRRRLVLLYCLACRQSPQEASCLPVHLHLPDWYRRGNRFPQFLSFTACRDAITNEFAGMFSEQFQEAMLNRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE5</accession>
    <name>A0A9Q8USE5_PASFU</name>
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    <organism evidence="2 3">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <begin position="161"/>
            <end position="171"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="182" mass="20747" checksum="C79EADFE1864977D" modified="2023-09-13" version="1">MKLRDRRKNTFIRCVDAPGLLLTCKQIYSEATGIYYSMSTFEVWYSSTRLARRSGNTTTRLPEFLHGIGKAKRDLITALGAWSLWPVCVGRGSLSHHIEGGEDGGIGEGEPVYTGEPVKTYREYLARPKKEKEERQREREGRRQKMLERMRELRARERKGNGKVRTKAKAKRGLEKVAGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT85</accession>
    <name>A0A9Q8UT85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765918.1">
        <property type="nucleotide sequence ID" value="XM_047908444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT85"/>
    <dbReference type="GeneID" id="71989174"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09296"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="71"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="26462" checksum="247E481E53890441" modified="2023-09-13" version="1">MQAIRIANNRLPQVINATRPYTTTTNKMSLFPRFINNEFAPMFQLMDDYANHVQRRGGGSGNGTLSSGFPSSLRTFTPKFDVKENKDSYELHGELPGIEQKNINIEFTDAQTLTIKGRSEHSREEGERPSGFIEGVQEQGKLTEGEHKDNYHKPSVEEEGAQNNSKNTQVQKSQGEQKQHSRYWVSERSVGEFARTFSFPTRVDQDAVKASLKDGILSITVPKAQAPTSKRINIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUC8</accession>
    <name>A0A9Q8UUC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767129.1">
        <property type="nucleotide sequence ID" value="XM_047911470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUC8"/>
    <dbReference type="GeneID" id="71992200"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12322"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040288417" evidence="1">
        <location>
            <begin position="20"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="21786" checksum="418CF88960B7B381" modified="2023-09-13" version="1">MARTMRVLLFGLLTAAAAAQSSGMDNMLFGDFRHLHFLQYESSPSSYTSLAECRSAFLQPSTIRQTPPIGQETFAVSTYTSDGLTYATTYAVTPASSGQRTTTELDPAATGLRTTTIGDAVIVQQPPYTTIYQQYTGSSNLASASTVATIPPDFVEDVQGTIIIVFPRRFVTSVQYYTGTSLITEPITETIPPSGDSPGTILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUS2</accession>
    <name>A0A9Q8UUS2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polyamine transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11947</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767612.1">
        <property type="nucleotide sequence ID" value="XM_047911095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUS2"/>
    <dbReference type="GeneID" id="71991825"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11947"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
        <property type="term" value="F:spermine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF38">
        <property type="entry name" value="POLYAMINE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="9189" checksum="A1645B7143DBA7B0" modified="2023-09-13" version="1">MYTIDVYGPLNGASAMAANGLLRYILSGCFPLWTVQMYEALGIGWATSLLAFVCVAMLPIPFIFFKYGPAIRRRSRYDTIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVC8</accession>
    <name>A0A9Q8UVC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_13168</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768136.1">
        <property type="nucleotide sequence ID" value="XM_047912316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVC8"/>
    <dbReference type="GeneID" id="71993046"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13168"/>
    <dbReference type="OrthoDB" id="438052at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18182">
        <property type="entry name" value="ATP-synt_Fo_c_ATP5G3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.20.10:FF:000003">
        <property type="entry name" value="Atp synthase f complex subunit mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031:SF0">
        <property type="entry name" value="ATPASE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="7 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="15">
        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO23770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="15868" checksum="5BB3670481F971DA" modified="2023-09-13" version="1">MFASTKLASSALRVSVTQQSRRMLSTPRGAAPLRSSIARQPIARNGLIQSNGHNAFVTHSLRNTAQSRGITAETTTGAIVMAAKLQGAGLATVGLAGAGVGIGAVFAALIIGVSRNPSMRGQLFQYAIMGFAFAEAQGLFAMMITFLMLYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVD9</accession>
    <name>A0A9Q8UVD9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspulvinone E synthetase melA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13164</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768138.1">
        <property type="nucleotide sequence ID" value="XM_047912312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVD9"/>
    <dbReference type="GeneID" id="71993042"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13164"/>
    <dbReference type="OMA" id="PIFFFHP"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="593"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="5">
        <location>
            <begin position="683"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="947" mass="104276" checksum="1841E31EA4432788" modified="2023-09-13" version="1">MPATRQHPVHILDLLKDAAASDPSVGLLYLNKGLAGEAKRVPYAQLLKQAEDNAVRLRKAGIFDHGRTVITYFDTHEEHVLWFWSVIAAGGVCAVLNPISNDPKTVAGQLDNVKSLFGDTPVVTTHKLSSIFAARRLNVGSVEDILTPRKRAAEIEDNGVLSRTHPFDPDKTAAIVFTSGSTGHSKAVKYSHAALIASVQAKAAHLSTHGLTFMSWISFDHSACLCEVHLQALFVHSDQVFAPTADVAVEPHRYFEILSRYQIGYTFSPNSFLAAAANALAEHDESGQEIDLSHLRVLFCGGEANRTATLQATDQIIRKFGAPKRAIKPVYGLSETCSACFYNLEGPDYDVKYGNIFASAGKPLPSVLEVKLVDQEEDQKVSDEGLIHLRGDVLFQGYHNNEEATAACMTADGWMNTGDIGKFDENGNLLLLGRAKEVLILNGQNYSSFEIEHAIETSDIEGLEPFYTAVFSTWDQDRQSEAPIVLFNPTEAAIGPKNLRATLQAVEKCVFSICAQKALHIIALPKSLLPKSTIGKLSRAKLKKSFETGAFDDFIVSERAPPVKSNDINGTNGHTNGTNGHAVKTFPSPLQKEIAEIYASIVGVSSSELMGQDALLSSGINSMGFMRLKKALENNLKIHQEIPMPLLIRCHSVADLEHELTLLGTVSTQYDPIVPLFTEGSKQPLFLLHPGAGEFLCWIGLLKYLPDRPIYALRAKGLHPGEGTFDGIEDLLKCYYDAMRRVQPHGPYAMLGYCFGGLLGFELGKMFEAAGETVVYCGGIDNPPDPKPTIGQVQYRKLMIDVLPVVTELTEDDAQKFADETAHLSDEGFYEILFTKFSPELIENMDITVPRLQAYGRVEDVMRQIASKYEPTGDLGTMDIFCADPMPHFGATPEVWKRDVLGGWREFVRGENVNFHYVQGTHISLIKEPHIKDFQRIVNEAFEKRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVR1</accession>
    <name>A0A9Q8UVR1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVR1"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="127" mass="14044" checksum="3F6A3D771329BCA3" modified="2023-09-13" version="1">MIAIAGNDQEQESNEWKEVCRKAEIMAMAGDGEHLERALKGMILELLGGLKALRSQIGQIINRTVAAKTAIKVYISDQQEQKEIEGLSGKEIIQKIGIQGIIGARKEKGGVLKLFTAQEQDRKRLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVZ9</accession>
    <name>A0A9Q8UVZ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768826.1">
        <property type="nucleotide sequence ID" value="XM_047912705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVZ9"/>
    <dbReference type="GeneID" id="71993435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13557"/>
    <dbReference type="OMA" id="CMLNTAV"/>
    <dbReference type="OrthoDB" id="2874071at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002598">
        <property type="entry name" value="PRK02253.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42680">
        <property type="entry name" value="DCTP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42680:SF3">
        <property type="entry name" value="DCTP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22769">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="17937" checksum="8FC7122861CF160A" modified="2023-09-13" version="1">MIIPGKTAVARGIIRGLRDRTVQSQPCGVDLSLRHVLRWTSPATIDLSNTFRAASATERIPFADDLNKVHLSSGSYLVEFNEQVDIPLDIMGQVCVRSSLWRSGVLLRAGVMDSGYRGAVGAMLQVASPHGITLYGNARLAQMVFHQMSESVDGYDGAYQNASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWE0</accession>
    <name>A0A9Q8UWE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769261.1">
        <property type="nucleotide sequence ID" value="XM_047913590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE0"/>
    <dbReference type="GeneID" id="71994320"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14442"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="27640" checksum="E6085200C754AFAE" modified="2023-09-13" version="1">MATTTQRLARTILRPSRGLFRSTPLLGRMAPSTGRSLTFYGVRPFSYHRPTPEIQDDLEKVGEKLSHQSGLEITMNIFDSTAQCPDGRKMVLSAIQTEQSRIQLRQADLYKQQSSLMRELKSAHEADLKDILASSPKIQRRVSAFKDDAEGSTSRGEKVSTGTSITESQAAAVSQPDRTSPSRAAGDALKLRAQIPTEQLKAEEDGELSQDEAKSEKEEGWRVFDTLTLSITLVAVGRLYNGIAISGVSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWG8</accession>
    <name>A0A9Q8UWG8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Piwi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769367.1">
        <property type="nucleotide sequence ID" value="XM_047913254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWG8"/>
    <dbReference type="GeneID" id="71993984"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14106"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="607"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="998" mass="110449" checksum="14F44E6CFEF53E9C" modified="2023-09-13" version="1">MSGNQNNKNKKNANKSTAPPMDGQLAIAMQGADISGNDDKPAKLPFELQQDGQPKINPEDKKDKDPSFYDEEYAVSNITGTQGEKLDIRVNRLAISYNLLPKEFYCYSVALPRISGRVVTKRHIKKFLMRETLITGQPWSAAFASNKIFTDWDSLIVTADPKIGLPTQQGDKATATFPFRNQSDPPGTAPTPVTSTITCLAVISRSGLTDYLGPDGINAPTFNHSVWMRIFNMMLKHFAAQANNTITIGNKLFRTVPSNAQRLPSGLLPQQGFFASVRPVNKGLQVHFNTAAAAFFPAIPLHKFLQGYFGPTLNLESVNGHLRAEIVATITGLKVRYMYNPPDPDTRARSPPLANAAAGRLKTVNSLGGSADAVSRPLQGYPAQTSWTVEQHFNTNVLTPPARIQCPKLPLINVGPKSTPQNRNAEVWIPMELLMIEPNQPLRTTVPENDMTPMATHSRRRPLQNVALLEGAGLQLLQRSMLIQHRVMQIAGGAGQLMHTVGRFLPLPELQYRGQGRAEKHRMKSGRWDLKRQKFRSGTKLDKLLVIIVADANLDKSQVQQTLNKVARGLDGYGVECTGAQFAHAPNAGSVHLSAAYDSFRQPSIRTVLVILPRKDFNMYSEVKTWGELGKGVNTICVTKDNATRSLHKPDFQGNLALKFNAKLGGKNHTLGNSFQGLLHWESGATMVVGADVTHPGPSSIEYCPSIAAVVASQDKDCVQFPGSMRLQASRTETILDMQGMMVERLRHWKVKNKDTLPDSILYYRDGVSESQFAMVKQQELSAIRAAYTQVAGQDAKVAITVVVCTKRHQTRFYPRAKQEDLGEKELEHFDRNMNFNNGLVVDDPAIRGPHYFDFYLQGHQALQGTARPCHYFVIENGMDFGPDDLQMITYGLSWVYATSLTPISLAAPAYYADKLCERGRAWLRPLLVRGHGLRPTPQQVAAIIAPLGQHATDQQKRNHVAAHYASGQNAGPVIFWPRNGTLKNPCHQAIEDTMFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWL2</accession>
    <name>A0A9Q8UWL2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_14382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769471.1">
        <property type="nucleotide sequence ID" value="XM_047913530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWL2"/>
    <dbReference type="GeneID" id="71994260"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14382"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="32"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO25105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="47462" checksum="AB57E725B85E7337" modified="2023-09-13" version="1">MFTTSWPYSNGGDGDSQPLSNTANTPTPAAAETFECGICANDECKGNPYIADGSPVCKECVIENLVPQFQKALEFEDSYPPPWGSAILDVTAFEDVLGEDFVARYKAQEEKYKIPIDKRRYCKNTLDAGEECNAILLPGKPDLPSNGQNFSCSKCLKSSCRDCDLPIQEGHVCLPVDGVVGRQIDAYDGLKRGRDYQECPGCGLKCELSEACNHMVCPRPHCRTNFCFICGVEAGPQPGHWTARGCPRWGQPREEVVAHEARQPDDARAREVVAQVQGAIGRQLIQEGGWIWGFDDDAFPSMVTRLVSPIPGCDTDVLICSSLFVETLVRYYGGVMMPITIMDERDHRAWYLIGYTGRFPERDGEDFTVTNATMVGVAPYGRQEWETDLVFTVERSIRQALALSPEGLNTIVEMIYHMTGLDTMTWDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXS0</accession>
    <name>A0A1P8YXS0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08361</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">0WU</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943135">
        <property type="protein sequence ID" value="AQA29306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759752.1">
        <property type="nucleotide sequence ID" value="XM_047907509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXS0"/>
    <dbReference type="GeneID" id="71988239"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08361"/>
    <dbReference type="OMA" id="ACYNKAF"/>
    <dbReference type="OrthoDB" id="3478218at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573467" description="DUF7888 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7888" evidence="3">
        <location>
            <begin position="42"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQA29306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="170" mass="17883" checksum="D6E579C8C4204951" modified="2017-04-12" version="1">MKLSVAATSFLAGLAAAAPSYRALDAYEEKALEKRQLEALSIAIIAGAISGVVSASASFAIQKIASISSNVADWDDAREEFTQTTVEEMIKSAKSNEAAICCNVGYSVSDQSKIRGLTSLNLISGPLKTDYDCFFYSGPGTFQLEGNGGFINIAIQDGPCKYNSGTLTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L542</accession>
    <name>A0A9Q8L542_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755335.1">
        <property type="nucleotide sequence ID" value="XM_047901285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L542"/>
    <dbReference type="GeneID" id="71982015"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02137"/>
    <dbReference type="OMA" id="QNPPTTC"/>
    <dbReference type="OrthoDB" id="3623508at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="141" mass="15615" checksum="2E73E80C28768133" modified="2023-09-13" version="1">MCRKLTVCCQRFISKNVSVSDHHIIFSDLKVPCIEPGTAKCRSGEADLKDFQNPPTTCAGAAEGYPIRSSQCEAVCHAALRKYGESLHRMNTAGPAKKGWWASWFGKREEGDVESSDKGLFVVSRDPEDRPYKESRASMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5G3</accession>
    <name>A0A9Q8L5G3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755559.1">
        <property type="nucleotide sequence ID" value="XM_047901199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5G3"/>
    <dbReference type="GeneID" id="71981929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02051"/>
    <dbReference type="OMA" id="HKAGPPF"/>
    <dbReference type="OrthoDB" id="206335at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000019">
        <property type="entry name" value="RNA exonuclease NEF-sp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="345"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="154"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="527"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="727" mass="79542" checksum="57ACBD315D0DC18E" modified="2023-09-13" version="1">MGGGKRSRDQYEADNRMGVAETLSMLRDPDGTSQDSTTPGHDRANGTNGATDGADSGGEWQTVESNRNKKRKKLPKKDGNYPSISHSPHSRLQSFVKISDLQNLILYLLADGTAPQWCSVRHHANVRKVVALMVPGLEAGMFDGKIDLAPSAVEAQQNTGSIDSDEPSKQNAAGEQAAQDDSGRLRASPDDYYPVKLKSDSVPESLRPLADMFEHIWPIKAPGDDKYAKMHSPLAAMLTAPILKTKEEKKAKGPQPPTEGKNWQNKRTPVTELLATTEELLEEGYTMHPAHFADSLSADAESARRVSAKTTTDDGWFDTTNIPSLASGDAAEKDIQQGSVTAGRKVLAMDCEMCITSPAGVTPQVFSLTRVSLVDWDGQVVLDELVKPANPITDYLTPYSGITKAMLEDVTTTLDDIQQKLSTILTPQTILIGHSLVSDLNALHIAHPFIIDTALLYPHPRGPPLKSSLKYLSQKYLSREIQKGHGSTGHNSIEDARACLDLVKQKCEKGKAWGTPGASGESVFKRLSRSTRPKRDKINPSGEDEPRLGAIVDWGDPTRGYGAQAKVAIGCEHDADVVTGIKSALTGAEDGKKIPAGGCDFVWARFRELEAHRGWWNKSKLVDSEALRSTTATDAAEKSLEEIVKQTVQHITDVYESLPPCSALVVYSGSADPRELTEMQALQQKFKEEYRVKKWDQLSVQWTDVEEQKLRRACELARRGVGFITVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5I0</accession>
    <name>A0A9Q8L5I0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="515" mass="58816" checksum="F1DA9531A8E25BD6" modified="2023-09-13" version="1">MIESARRFCIEILEAVLHLTLAMTDPIGVILAQKLQNSILLNRLAKFTGISRKELQRPKRPSVAIPSVESPAAQTKPSAESLFRTPTSPEGKEYGFGNEFEADGNEPAREYQDPQSLRDEKYCVFDGEAEDDYTQGPARLVMAFDGVQDCPALLMRMDLSQLIQHAAYTRRLLGKKRHFAERQGDEIDEFEYTVRDEISSHKIRLAELTEVFPGEEPKETDPEVLASIQRQIDVLEGVLERMSAKKARLHDGIRGLEMSLAETQDDILSFLAEALQDATLIPEQDEEEDLSVEQFDLQAEYQATAKEMSDDQDPDAPPEPLETGDGFLRPNLPTPTHEEQAIAAHRDAVREAREFLNTAQAQFNRKEYDQECDKNENLAAYTTWTEFDNHWVQRYREITNELVEAEEAYKQAKASAIEAGIPKENVLSEYDPRPDHDGYPLSEDVGQDRVDARRYIVDDWMEKVPDDAEPDFQDEVDVDDWDGEEIDISDSISCVDRYMYRAQIDEWRQQALSTR</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        </source>
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        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO11405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="45942" checksum="E4A0FCC34DA6100B" modified="2023-09-13" version="1">MSALPSIRDKALYRYAYLQGRTSALPSSFSDLSGALVRKVASFVTLPLPLLSFLAVPLYGGSSTTASLVFFYATWTTCILVMSHDPILLEIGGTLAIRIFCFVIPALAFLLGDCMAPSLSKRLKARGHRLLPDQLGRDKLFLVFGVSLSNVLLAVVLQALLEQFCTGALRMRSLLKVTSIVPLPLNILTDLLKGFVIRGIVHYAVHRWLFHTYDTILKTWHLSWQHSLKFPFSLVASYDHPVCFLLSTWLPTYLPAVLSRWHVLTWHIFLVLTSLEQLFVFSGYAVLPSTILIAGMARRMEAHFDSIQASGPAGNFGQLRLIDFLLGTSCKGGSALLDDVQDEAEKRAIQEQIDEAVHAAIASMNSKKRPGQESNGNREHGEGTYKSSPDASGEVDQAADSGHAQQRRSGRRQGTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5X7</accession>
    <name>A0A9Q8L5X7_PASFU</name>
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        </recommendedName>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33102" checksum="B0E50A42F3EC0D6D" modified="2023-09-13" version="1">MHIKREYTTMDDYSRDYYMSQSPPADPSIRICSVTNENWRGKNDPQERRRIQNRLNQRAFRQRQRAGESPRLYKARTASSEPSSEQGDEESPAADDEDEPQHSSAESQPTSAPSTTQPNGVADPATGRVWDELAQLINRNLLAAAAANATSIGVNLAALQSATPAVTPRPSKSGLTAALQPIQLQYQVQHDPIIDTIPHPRLRYNILRAIATRQLDANSFTTDLRASGALTNIQGQWLRGGLVVWSSPEQLASWELSELWIRRFSQLLQGCDDLLAATNAWRSRRGERLFPTSLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5X8</accession>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="71980938"/>
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    <dbReference type="OMA" id="HPRECIV"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="2">
        <location>
            <begin position="3"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="35103" checksum="BBB3F13F417CAF1C" modified="2023-09-13" version="1">MTMEQQLDAGIRYFDLRCGIVDDIAEMVHGAALLGLKLPEVMNTIYKWLDAHPTEAIIVQIKEDRESERSTVHFAQAIFACVSTRSERWRTANTTPTLGELRGKIQLFRRYRGPNLWAYGIDVTQWQDNPSVPFTITTQNMVQLTIQDHYSFSDPQSLPALVAIKGGDVSGLLERASKDLDPGHWYINFTSAYEFNFYYQLTPRAIATGGYYQFRWIDGINVRLHNWLRTRVGRQHYGIVAMDFPDTDLVSELIRSNFKKHNEPVWLVMLCIVLSIAALALMVLHLAGFSSVQELYPGISSLAVKEIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6G1</accession>
    <name>A0A9Q8L6G1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756102.1">
        <property type="nucleotide sequence ID" value="XM_047900124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6G1"/>
    <dbReference type="GeneID" id="71980854"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00976"/>
    <dbReference type="OMA" id="KYRVAQM"/>
    <dbReference type="OrthoDB" id="3644453at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="585"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="653" mass="73986" checksum="969CCE6A1A1586A4" modified="2023-09-13" version="1">MDETTFQRELSLLKYRVAQMTSTFQTRSPYVFHVPAVCNDAYFSDQLLDVKARLQAMQASIDTLHATTRNCQEPQDRMSEYEPPQHNRLALPSGPLFWQLFTSLRTDVHGLNGRVGDLEHNVSDLEDRVDKIDPSFTPPGSADTFSSFGWSQQVRDQPNPAGEAKAFAGEASLPAFVYPYSDHASQGRYHSRDSLWGNIELPASTGDQADLSARPQQPAPEGVAFRDREIAQLEELMRGAHDSLRGKEDVIGQKDAEISTLRARIKELDRVAFERTNQVQCYGGILAERQREVERLQEDCHAKDCHLNTWEMKFHDMQQSLSRKKMQLSQARQELQQVKREDVELRDFEATLAQKDREVKELRDFCEAKESVAQQQEQIISRGATLIEEKDRQINMLDDDYRTECRERARLGRLLHERDDEIEQLKQSLHHALMPNAKAKVQDEKPALPARPSQILPEAHVHNGLLSYSPFATAGTRSATRGEDWTPKAFKNYAMLPHESLRASAWNKGRSCSDHYKFGVPGVATPPPSNTHIAKRDERRDLRRSDSVKLLRRLALAEEGGSRATRPGAESGNVANRTRLPLDDAIVSPPLPAPLPPRKVTSLEDLSRISRHERDADPQHMPKSHSLDELSDRPLLQAYVEDGENSGDRHGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6L0</accession>
    <name>A0A9Q8L6L0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase cicH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756123.1">
        <property type="nucleotide sequence ID" value="XM_047901033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6L0"/>
    <dbReference type="GeneID" id="71981763"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01885"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="553" mass="63048" checksum="5997E295F5E0AFE0" modified="2023-09-13" version="1">MASALDNGARKFIPSTQLHSHCGFNMIADIILSILLAYWPLVLAAFLGLYLLRNKYHHGLDKYPGPTYAAFTDWWRYFDVRSRRAEQTHIQLHRRYGDVVRLGPNVLSFADPKAIKIIYGLNKQMTKSDFYPVQQAVAKGQRLQSLFSTKDENYHASYRRCVNNAFSMSSLIGYEPLVDSTMGAFIEQTKRRYCDTGKSCHFSKWLQYFAFDVIGELTWSKRLGFVERDEDVDGIVGFVGKFLDYCAPVGQMPILDMIFEKNPIKLKLQKWGISKTVFPVTRFALAQSADRASEMEKIKQNGSLNEASGKGVDLLMKFTQAQHDHPEFMTDKQVLSSCTSMIFAGSETTAISLSSIFYFLIKNPRVYSKLMVELDEAARDGSIAERDHNRVSWSESLKLPYLDAVVQEAMRLHPAPGLILERVVPPQGMDILGHQIPGGTIVGCNPWVVHRHPEVFGADPDTFRPERWIQAKPDQLREMKASMLQFGAGARTCIGKNISLLEIYKLVPTFLRNFEVDMADPVSEWKTHNAWFVRQLNFTTRFKPRQSIQSPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7T9</accession>
    <name>A0A9Q8L7T9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipid phosphate phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756775.1">
        <property type="nucleotide sequence ID" value="XM_047901368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7T9"/>
    <dbReference type="GeneID" id="71982098"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02220"/>
    <dbReference type="OrthoDB" id="8907274at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF154">
        <property type="entry name" value="PAP2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G09730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="120"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="283"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="414" mass="45159" checksum="4B800D6872359C70" modified="2023-09-13" version="1">MARMAINKGTLLGATGKPSKKLVVSYLFDWFIIIVFAAAGAGLSKVRPHHRPFSLLNLEISNPVVDEQISIWMLGVIAFVVPAAIIALITLIFVPGGNVRRVSTTSQVIKLKLWELEKGLAGLCLSVAVAFFITQGMKNMFGKPRPNLIAKCQPDLSNIGDHVVGGYGQDLSISWTLVDFSICTQPDIAFLDDGFRSFPSGHSSWSWSGLLYLTLYFCSKFAIGLPHLPTPLEQQQQQQQPLRSTIPQNGDHELLPLHSNRARGDSEDTKREEDTTYRGAAGPSSHHPTSDDISTSPLWMRNAAAAPPNYLIIPALLPVAVAVYICSTRYVEFYHFGFDIISGSLIGIATAYLSFRWYHLPISRGQGWAWGARSRNRAFAIGVGTGGYVGEEGWETASGGRGKGRDVEAQGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7X4</accession>
    <name>A0A9Q8L7X4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756813.1">
        <property type="nucleotide sequence ID" value="XM_047900707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7X4"/>
    <dbReference type="GeneID" id="71981437"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01559"/>
    <dbReference type="OMA" id="FRMSCEF"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="247" mass="25945" checksum="E3211B297BF55E60" modified="2023-09-13" version="1">MSAKQEEQSQSASAEGEGNLNVGANASGNAQASQRSSKRTPKKLGQKNQQQQPTPDQTDEADAEGGAEADGQANGNVEAEAEADGEEEAQQEQPQQQRQQSRRRQSRGRGRKGGQESDTESVARSDQSAQGGRRQRQRKNKQQAQTKDSQGGPLDDITEQLPGGELVNQAGDLVQGTAGDAVNSVGDTAGKALGGLTGGGQKGQQQGGGEEEEGGGEQLRLRLELNLDIEIQLKAKIHGDLTLGLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8A5</accession>
    <name>A0A9Q8L8A5_PASFU</name>
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        <submittedName>
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        </submittedName>
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        <name evidence="5" type="ORF">CLAFUR5_00927</name>
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    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757122.1">
        <property type="nucleotide sequence ID" value="XM_047900075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8A5"/>
    <dbReference type="GeneID" id="71980805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00927"/>
    <dbReference type="OMA" id="MVYDRAM"/>
    <dbReference type="OrthoDB" id="67540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034066">
        <property type="term" value="C:Ric1-Rgp1 guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009771">
        <property type="entry name" value="RIC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07064">
        <property type="entry name" value="RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="834"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1084" mass="118246" checksum="1AFCBEE42018D4E0" modified="2023-09-13" version="1">MYWPIGAPDVFSLQKQAIPHASLTCSHDGLEGEGDVEAGHSAGSQRGASGNGRQDQDKARGAAALADGEILDAKISRGGSVFITITRSSLVIWQTKPTVALAGVVRSGPSIKSYGPNVALLLRPDALIIVVQTALGYLITYSLATDPAARVYQTVLPDSTKHQRRTSTDGYTNFRRASAAPSGLGPAENDGMREVNVRFRMVMRIDAGISRALALEDELIVATQKPAALQCIRWVAENGVSQTSTELVSRMQWVGKKVIVIEMLHDRPMNLATWITSDGRAYAVQRRKSRSSEIDDPKSLFQGFCFREPETDDVAATKTAINARFSLIAVGCTNGSIDIYTVKDYTGNIPLSHKVRLPVGLATTGPLTSLAYSPDGYCLFAAYEHGWALWTVYGKPCANTFGADRPQTESNDEKWLLGIRNAFWVGGGSELALLPIGDNRLWLIDIARNAVTGCFSSANVSRGLLQSSDSVMLYKGHEVADTTSLPLESSLWQSVQIPNHYLMSQWPIKLAVLSPDGKYVAVAGRRGLAHYSVASGRWRTFEDPQAEQEFAVRGGMCWYQHILIAAVEVGNRHELRVYSRDKALEYPQVQHVEALSAPAISTTVSGADSLLVYTYENTLLHYVIVIGSSSARLVQVGQIGFHGIIRAPPRVRAISWILPEDQLEHGDPSQDVATASVLFLVDGKLVLLQPSTNELGELKYDMRVIAHNVEYYMLLRDSPTATAALKGSQATSVTPPIDGLSLNGHLGHSLRDSLWYFDGTGFHVWSDVQDVLACAPNELGRDLPSAVTIPLDFSPVSALVGSGTVAGIESDLVQRRDVNFSFFRHAPRSQLFLPQLLRYHLTEFNSPAALHLSSSYQHLPYFSHALEVLLHDVLDMEVDNRPSPPETALLPTVLSFLSSFDSYLDVVVNCTRKTELRSWETLFSYLPPVIELFEQALGQGRLNTAAGYLLVLHAFEQDSFQIHEFAQLLRRAANEQDWDLCKELARFLVGIDASGHTLQSALTEAGLMDRQNGPFASVNGALEGSKTSFTLTSQKASDVAATSGRVDMSHTNGSSSHAMPDYFSIGGRNSIAVNLEAEATTPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8I2</accession>
    <name>A0A9Q8L8I2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SWI5-dependent HO expression protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757113.1">
        <property type="nucleotide sequence ID" value="XM_047900535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8I2"/>
    <dbReference type="GeneID" id="71981265"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01387"/>
    <dbReference type="OMA" id="NMHQHNG"/>
    <dbReference type="OrthoDB" id="3918393at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    </feature>
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            <begin position="239"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13102.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="30054" checksum="E7E0BD28B88A9667" modified="2023-09-13" version="1">MADPSLTTSPPLQPTQPPGRRNRKKLRTVSVHHTRLSPATRTPPAESALRYFVDDSGRVTETGDHPGPQTPMPCSNYSNAAQSAGLPIMTLNGTIKGHDTRRSNATNDQAATPRLPLEPGVESLSTAVPFGPRAHEGFPTISVKNSARFGLTRSIPSQIENTTRPSSTADRPGASTPQLLRLEPRCPIQGFTYTFDPAGTTALPETRMIVYSNKSGHDLLREIKRPANYIDQVTEQRTPPRKSARYIHRHDSGAQGLVMPSPTLNSASRPARRQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Z7</accession>
    <name>A0A9Q8L9Z7_PASFU</name>
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        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
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    <organism evidence="14 15">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="14">Race5_Kim</strain>
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    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
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        </cofactor>
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        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047901343.1"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
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    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        </source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO12908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="999" mass="108812" checksum="660A31340217C334" modified="2023-09-13" version="1">MSTANISPAGGSTYDSSTMFVGDGTWDSSRNSFLLPNLQGLNFDTMRYNGMGNRFRDLPQYHSLVTGHAVVAAITFAVIVPAAIFIARFGFFRTEGRLAFKMHIYLQILTVFLATVVLALGWFAVGPERSLSNPHHGIGVAIYVCILVQFLYGWWFAKRERKRKTPHPTIPLRVHIHRLFGRSIALLAFIQIALGLTLYGSPRALFIVYALWGALLVFLYLALEYKNKPRLGAGGPRAPSEYYSEYSEGYVTSDPSRVTDNRRRRDSSRDSRSSRGESHWGRKVLAGAGALGAYKWWQGRRDKRRDGRSDRYEESEISHYPPDTPGRQSRPQSSMGRPPQGPPGAGYGPPGPGYGPGYGPGYGPGYGPPSHAQEPPGPPMGVPPPATYANARPQSRGSHRPRRQDETVMSPQSWENDEYVDEKYGGQPPKRSNTWRDRILGAGAGIAAVQGVKSMFGSRKRRNDGYVDSELSYRPGDQSMVSQTDVSRVQAGQAPFSPSDPRNNRPGNTQPMTPTRPSMGRRPTGRPPPGRASVDSMSYDDDESYAPPRRDDVDDSHTLRNSIATLGVAAGFREWNKRRKERNEQQRTDRIRRQELDEEEKFNRRNSNRYPRPQDASGRRQSMSGTLMTGPEGPDPAQGSNPELSRHTFRPDTSHPPLPAAAGTIPSSGGGLSNMDGQGFTQNIVQTQQQQQQLPYNLPPPPPGPPPHAANPMDYPQPGSLQMPQGAIIPDPLRLMNEHHQAQQSSSQFYQDGTSAAATEAAAIAAANAAAVGAPLSQRTQSQSPSRRRDSRTRMHSGARRNSSAAASGSRLDSGGVGSAGSPPVSVKVNMHPDGRHVTLRRLGEEEAAAERAVRRRERRSRRASSLSSGGEEPSRYRRNGGIRPSSQQPITNVPPPPAMSSSLGGSHRPPTELNLPPVPPIGQIPQASKSPQAQPSGLLPAAGPAGSGAVGSPGNVPGQSDMGTGTDVSAFDNNRRRRRAERARRAEAAKAGNRVEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA14</accession>
    <name>A0A9Q8LA14_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor SWI6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757908.1">
        <property type="nucleotide sequence ID" value="XM_047901563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA14"/>
    <dbReference type="GeneID" id="71982293"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02415"/>
    <dbReference type="OMA" id="HHIAMMA"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0183">Conidiation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="8">
        <location>
            <begin position="96"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="585"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="260"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="751"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="806"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="937" mass="102343" checksum="84AA1F01343666C1" modified="2023-09-13" version="1">MPPTPQQSQSYHHQRGMQPSPQQSSSQPNGMPSYASHNYNTSFDGSQHGQSFGQPAPAPYAQSFPNGPVSNPGYARSFGDQAQRYPMPYATEKPQIYTAVYSGVNVYEIEISGVAVMRRRSDGWLNATQILKVAGVDKGKRTKVLEKEILPGEHEKVQGGYGKYQGTWISYRRGLEFCRQYGVEDILRPLLEYDVRADGSSGPGQQETPTKEQAMAAQRKKFYTHSSLDPRQNGTPGSNGTFFSNISPTTSVALAAMNKAARMNSPAPRAGSTPKPANMRRPSHQDNGQSQSQQSAASDAKGADSRYNTQNGEPPRKRMRPDSQDGMGPPNLPLDASMRSGTPTEVNESFYENALLQDAVNGNGEPIALPPLPSPVTQVQQEKMNMILSLFAESGRTDYASHPALQELSNEDLNMPLDASANNALHWAATLAKAPLMKLLIQKGASIWRGNAAGHTPLISAVLVNNCWEFANFPELLEMLGPLIEVRDMTGRTVLHHIAVSCGIKGRGASSKYYLEALLEFLVRIGTQPNSTAAKNVAAAAANMHYDSQLSNGDGSSQDTAVPGPRGPVNLSRFLSHIVNARDKAGNTALNLVARIGNRSIIQQLLEIHADPSLPNNKGVCAKDFGVGIDEDDAPNPSGGLVSQQSSMQPPPYPMPNQDASDAEAKPGAPEVRAEDMGQEFIASMTSMLTQNLASHKESLRSRTEKIDKLNEQIRELSALQKAGLEKLQEMKERLRVREERRAKVANLRREVEKKKTAARKQQANHTGRAIELEPDWLDLPSQTNGQSRLSLAGRMPSQKALQARLTAYRGSNNNLRQQAEELRSRSIDLERLYRKVVSLCTGVSEDKVEESLPALLAAVESEKGGIGHNEVGRVREFLRRVDTSKDSQVAKLDPNRSYDGPMLQINPTVVAAAERAEAERRAQAMRLPGMQGRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA31</accession>
    <name>A0A9Q8LA31_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757860.1">
        <property type="nucleotide sequence ID" value="XM_047902677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA31"/>
    <dbReference type="GeneID" id="71983407"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03529"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF4">
        <property type="entry name" value="GDP_GTP EXCHANGE FACTOR SEC2 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="129"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="172"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27706" checksum="62DC78A03400E8FC" modified="2023-09-13" version="1">MAYNTPIGVRATAQRHGAKDSRISLDVGSSKDEVFRMRLKELEDENSDLAEKATAASQRFVDYENNILQLRTQLREQQERHTAALAAHHAHDPEPSTPVHTASPGLSRLGSFMRKPSLAATISGPSPREQELEASLAKEQYARIEAENKTKQVHAEIEELSASLFQQANDMVANERKTNAGLQARIRDLESAGADGPVIAARKENEKLRQKLQVMEQRDVERRKRLDRLEAAQKRIDRVRTMLKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA35</accession>
    <name>A0A9Q8LA35_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UPF0620 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757960.1">
        <property type="nucleotide sequence ID" value="XM_047903022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA35"/>
    <dbReference type="GeneID" id="71983752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03874"/>
    <dbReference type="OMA" id="FTFGMPK"/>
    <dbReference type="OrthoDB" id="27095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040303056" evidence="7">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="8">
        <location>
            <begin position="33"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="25502" checksum="5866FA872BC80A7D" modified="2023-09-13" version="1">MFAPKSLVLLVCAALSTAARLTVSIPSSQLLPNPQTLPSSSHAVLLGPPGVRYDALMRRDDTFVFPDVPDASYLLTIHSRDYFFPPLRVDVTQKEGESTQTVEAWQTFRGNEWSNKGPSYGTGKEDLTVAVRPLGQKDFYQTRGGFSVMSFLKSPMILMGLVSVVLIFGMPYLMENMDPEAKAEFEEMQKKSPLMGSQGAANQLQNFDLAGWMAGKKAPAADSNSDGGSARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAB6</accession>
    <name>A0A9Q8LAB6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03225</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758154.1">
        <property type="nucleotide sequence ID" value="XM_047902373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAB6"/>
    <dbReference type="GeneID" id="71983103"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03225"/>
    <dbReference type="OMA" id="ISTHPCL"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000049">
        <property type="entry name" value="Putative uracil phosphoribosyltransferase urg2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF4">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="222" mass="23835" checksum="6BBBCB02321AF896" modified="2023-09-13" version="1">MSNIHVSSHPCVRSKLSQLRSASTNARHTKALVHEIATILGVEAFAHGLQAQQTGTDTSPLGYEYTTEDVSLSTMTLVPILRSGLSMVDAVQSLLPSPISVHHLGMYREKSTLQPVEYYNNLPYQKAGESSKIPELAIIVDPVIATGSTACAAIETLRDWGVKRIISISILASQAGLQRAAESWPEAVELWVGGVDAETDAQGMIKPGLGDIGDRLYLTLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCF8</accession>
    <name>A0A9Q8LCF8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759253.1">
        <property type="nucleotide sequence ID" value="XM_047907382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCF8"/>
    <dbReference type="GeneID" id="71988112"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08234"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="419" mass="47323" checksum="94D58BFFC351E41E" modified="2023-09-13" version="1">MDAMNFQQRKDEKYQYLDPRLRNTEGVLLPETGAQFEGESQFDASYQSQDDFAGELSIDLEAGIPWISELELGPGDGRMVLQNHMPSATLGGQQRMTSDNLSRDMEEHMDVQGHTHSPNLADQSVMAPDHSYRDLEPQLHYQDGVDWLPTTPLPSHLQQQMLATPPASCSPRSIPQGDNALPQIALPQSRLQHSPHLNLNTSQPPLMVYRDTLSPYDAYRTPISCTSTQQDYFDAPSTPTRQPPMRRGRANSAVGYGMAHLMTEQFLEQSDQRFDIQRWAFQNTNVTNQMREVQSAPQAQPRQTSTGVNMKAVRRSARPNKTYNITKDTTKKERTSATNARKAFNSQRTYLVISRVRSITREGEASTNVMFAVADSSTKAGHGETTGNDTWRRSMDMYFQQDRGMVQKLDDDSEGMIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCG6</accession>
    <name>A0A9Q8LCG6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6 18">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 18">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_08248</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 18">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6 18"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759342.1">
        <property type="nucleotide sequence ID" value="XM_047907396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCG6"/>
    <dbReference type="GeneID" id="71988126"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08248"/>
    <dbReference type="OMA" id="EDNEPHT"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000006">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000007">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000003">
        <property type="entry name" value="3-isopropylmalate dehydratase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012235">
        <property type="entry name" value="3-IsopropMal_deHydtase_ssu/lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001418">
        <property type="entry name" value="ACN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="20">
        <location>
            <begin position="13"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="21">
        <location>
            <begin position="535"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="747"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="761"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO14976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="772" mass="84126" checksum="03F75FE0964799D7" modified="2023-09-13" version="1">MPGVVKGPSTLYDKVFEQHIVDEKPDGTIILYIDRHLVHEVTSPQAFEGLRNAGRQVRRPDCTLATTDHNVPTTTRKNFKNISQFVEEDDSRLQCETLEDNVKAFKLTYFGLGDKRQGIVHVIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLMTRRSKNMKVEVNGELAPGVSSKDVVLYVIGQIGTAGGTGHVIEFCGSAIRSLSMEARMSMCNMSIEGGARAGMVAPDEITFEYIKGKPLAPKPDSPEWQKAVKHWSALKSDPDAKWDAEIIIDAKDIAPTVSWGTSPQDVVPITAVVPGPDDFEDEHKKNACKRALQYMGLEAGTLMTDIALDKVFIGSCTNSRIEDLRIAAHIVKGKKIAPNLKRAMIVPGSGLVKQRAEQEGLDRIFEDAGFEWREAGCSMCLGMNPDILSPGERCASTSNRNFEGRQGAGGRTHLMSPAMAAAAALVGKLADVRHLEGYEQALPSAKSAVKTVDAHVEDPESDVDLEKILDAPESNNNPQSKAPSGASAGMPKFTQLKGIAAPLDRNNVDTDAIIPKQFLKTIKRAGLSKGLFHAWRFNEDGSKNPDFVLNQEPYTNSKILVVSGPNFGCGSSREHAPWALLDFGIKCIIAGSFGDIFYNNTFKNGMLPLKIEDDKVLNTAFEEANAGRELEVDLEANELKDASGNVIGKFEVDEFRRHCLINGLDDIGLTMQDDEKITKFEKRRTEETPWLDGSGYLSKHRTGAVKVEAAPVPKTNRGEEKSEPLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDE7</accession>
    <name>A0A9Q8LDE7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759763.1">
        <property type="nucleotide sequence ID" value="XM_047907580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDE7"/>
    <dbReference type="GeneID" id="71988310"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08432"/>
    <dbReference type="OrthoDB" id="5595695at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.520">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.90">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10910">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="50"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="410" mass="43975" checksum="3A643CFC2877E3F7" modified="2023-09-13" version="1">MPFLIKDVRIFDGESTIENGSVLVQDGKIAHVSPSPIPFSGTTISKPGHTLLPGVIDVHIHANGGTPVALPQALRFGVTTVCDMHNEWYNIQKLHKQREGGDCADLKTTSFAATIDMGWPMPIVLMHDPSPQTQAEVATWPKLKTPADAKQYISDRLAEGVDYIKLMHESGTVMGQTFNKPTLDLQKALIDEAHAHNLFVVAHATCLSDTLEILSLGVDGLTHTFIDQPPTPDLIAAYTKNNAHCNPTLAAMGSGTSEGLATQERFAHDPRVQHLISAEGREQMCHCMSFAKSSSSKCANAYETVRQLKATGVPILVGSDAAGPAVGTAYGLSTHQEMALLVEQCGFTPKEALEAATRVNAERFGFGDRGMIKAGMRADLVLVEGNPLEGLECMLDLRGGVDGGEGLWCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDL9</accession>
    <name>A0A9Q8LDL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759820.1">
        <property type="nucleotide sequence ID" value="XM_047907357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDL9"/>
    <dbReference type="GeneID" id="71988087"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08209"/>
    <dbReference type="OrthoDB" id="3801489at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="26753" checksum="F1BAFC62979900C5" modified="2023-09-13" version="1">MVKSRITCSCAKDPCTARVVYTIGTSRARIKSLFALANSVSATSNTTTSIASNMTDLSRCRLLALPREIRDLIYAYLHQSALATEEPRGNESGNLLVLVTCAPLTAVLQLCKQIQSEYLEMVFNHIALRIAVPSDHKIMDGIKLKDGVPSKIFTRAVEILVNVDYVRIDDRLEEESGDELSVYLDGVVSEPEEASVQRQYKGDNSISDRDTRRGPRRSPLQKGTNSTVPHILGPQLLEEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDM0</accession>
    <name>A0A9Q8LDM0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_07853</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759842.1">
        <property type="nucleotide sequence ID" value="XM_047907001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDM0"/>
    <dbReference type="GeneID" id="71987731"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07853"/>
    <dbReference type="OMA" id="RQWYIRN"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000009">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000078">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="16">
        <location>
            <begin position="141"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="17">
        <location>
            <begin position="809"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="50"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO15476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1089" mass="123414" checksum="F0F95066135A8B96" modified="2023-09-13" version="1">MALNHASHNPTGEPTGPATGHPPPVSNDTKSAILEAANGDAKGQPAPGKDGGDNNGEQKQKSEKELAKEKAKADKLAKLAAKQEKQKAMAAASQPKQKEKKKQEILPPYQEETKKGDKKILKPLDDEYHKAYIPEVVESAWYDWWEKEGYHLPEYKANGEVKDRGSFVITIPPPNVTGALHIGHALATSLQDAMIRWNRMKGLTVLYVPGCDHAGISTQSVVENMLYHRRNGMTRHDLGREKFVETVWEWKDEYHSKITKVMKRLGGSMDWTREAFTMDENLSAAVRQTFVQLHDEGLIYRANRLVNWCTKLTTALSNLEVDQKELEGSTKLDVPGYDKKIEFGSIWNFKYQIAGTNEFIEVATTRPETMLGDSGVAVHPSDERYKHLIGKKVQHPFVDRQLPIFGDDTVEKDFGTGAVKITPAHDFNDFKRGKQHNLEFINILNDDGTMNENAGPFEGQKRFDVRYTVIEELTKKGLYVGKANNKMQIPLCSKSKDVIEPILKPQWWLHMEPLAKPAVDVVKSGEIKIMPETAEKSYYRWMANIDDWCLSRQLWWGHQVPAYYIKYKDGPEYDVDGEHWVCAETEELAREKAQKKFPGREIESLSRDPDCLDTWFSSGLWPFSTLGWPNKTNDFEKLYPTSVLETGWDILFFWVARMIFFGLKLTGKVPFTEVYCHSLIRDSEGRKMSKSLGNVIDPVDIMDGISLQALNDKLKVGNLAPKEIDRAVKWQKSAFADGIDQCGADALRFSLINYTTGGGDISFDVKVMRSYRNFCNKIYQATKYVLGNLPADFTPQAKGGKTGKESLPERWILHKLNEAAREVNEDLASREFSYATQAVHNYWYYELCDVYIENSKAIIRDGTAEEKQSAIDTLYTALEGGLTMMHPFMPFLTEELWQRLPRRPNDNTPSIVKAAYPEFDASLDDPKSERDYQLINESAKGIRSLLNENAVKTEGKAWVQPLTQEAYNTANDQKLSIKTLSGKALAELNILETGKLPASKQIAVYPVNAAANVFIELPGKFDPAKETEKYRPKREQAAKNVAEQERVIAQLAVSVSQQTREKTDARLRDVLSEQRAYDDLLQYFETTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEF0</accession>
    <name>A0A9Q8LEF0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase-like protein ustS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760240.1">
        <property type="nucleotide sequence ID" value="XM_047903177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEF0"/>
    <dbReference type="GeneID" id="71983907"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04029"/>
    <dbReference type="OMA" id="MDSYKIA"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
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            <end position="92"/>
        </location>
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        <location>
            <begin position="117"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="28050" checksum="671A1E2C5A9254D4" modified="2023-09-13" version="1">MSNELILYDLPSKGRCRSWSANVWKTRLVLNYKNISYKTQWVPFPEVRDTVAATGVSPNGEKAWTEYSVPLIKFPDGTYLMDSANIAPALEKLHPSPPLHLDLKIHEELMPAFGQAIMPLVPSVAMPEIARSVILECDREWFYADRERKLGASLDELERTNGGDQAWEKARPGFEGIREVLKKYKRDEGPFILGSEPSYGDFMLVAGIHMFSQFPKEKYEKFLSMCEPELGNLYEASKQWIQRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <location>
            <begin position="70"/>
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        </location>
    </feature>
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            <begin position="23"/>
            <end position="64"/>
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            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="14897" checksum="70A88E34C0BF2674" modified="2023-09-13" version="1">MDLHNPTNTNTGESLLVMVANNTANLRRNSIELKELLVALQQQVNELSEQVIILQAQVSDLNGQLMVERQGKVHTSPSHASLHAGADSPSDGERTRRSSKQPRVRYYRHDSGPPGLGSPSVGIGVGGGESGEQCVTMAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGV0</accession>
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        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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            <begin position="1"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="477" mass="53450" checksum="49D881334C71A6F2" modified="2023-09-13" version="1">MQNTFNATPQSQPAGRVDTPPESRTTNTVQNAAQWLRQRGRDDDNFDGRQWWEESDSESDQEESPCRSPIVATSEPTSPKPSIRSPDDDLDVAPVQPQPAQYPTRNDSRYWQKYRANMMYEADPEEPTQEASVHYPHDALTINSVESQPDHSPPHSNPGYWKEYWSNEAYWESYQHLSIKPSPLKIVKKEKPVSGEAEPSSEPPVLKVDKPLPALPDMRVTGVMANGVKIISLAEAQAQLKARVDNAPAIDGIQAQRPIKVNVTPPAPARRRRILGLSKLTASSASSSGTSNTASNTHKTTPTAPVPAPPTSQAPIRVVGDPRRDTLWTDFMPSPTRPPPPPPTDERKCPCPEHRAERAAAYTIPRKPVPSEHSEMSEPLHSPSVQYEIDRLQDRVQLTYDPDDDYDREPVIDTFVRAGHTSLHIKERVDPHTMASHYGREERLDGDENVERAKAKMHAYHEARRLGVEPSPTTDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
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    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
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        <property type="protein sequence ID" value="UJO17332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904814.1"/>
    </dbReference>
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        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L37a"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10056" checksum="351B197B0CDBC3FE" modified="2023-09-13" version="1">MTKRTKKVGITGKYGTRYGASLRKQVKKIEISQHARYTCTFCGKVSVKRNAVGIWDCRSCGKTVAGGAYTVSTPAAAATRSTIRRLREIAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHD6</accession>
    <name>A0A9Q8LHD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_06205"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="531" mass="60319" checksum="6206B6964D7DA046" modified="2023-09-13" version="1">MAEDDRTSIRINERSTTPIGGVYREVNIYDIFLVGSDPYNQLLPIAFKDPHTPLPDLLYWLNRRGFEGVVICNFRIVSPVLFEMILFAIGTWKVRKQKPTPQEAREEFEKFVKIFFAAKYVLTQEAMDDLFNLANATTMIEMQNLIGEVWPVRPAWDEMDGISVNNRNLLWHTVVSGGLGTTPAQCTVPNMYRGKVATLFDLSPENEAVKWDFLEEDGTLRRVDGDNEVLAHPRYPRSWWNEGENANHAQQNYTAKTAAPPPPPAGVPPPPPTAPAQHARAPEAFALYGPTSNIANPGRRYRPHPRLANTSDPTTFKWTPAQNNVSCLTTVPTAGVMYSLDERNLKGFYMGLLEPNSETLHDPKAPCFPKGSSKDMEGIPYVGFPAQGWFYDEVKGIVKVKTDQGTFAKSACFKLTNEEKDLIMRRSQANVEDYHKTLRRDKDGAKKKLEEHGEVQYFREESHAHFENSYLPIGSKVAPHRFDELQLGPNLARMYYTTSHTIGYQAQNPDVTLLSWARGLLDLFRRQYQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHD8</accession>
    <name>A0A9Q8LHD8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_06573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761799.1">
        <property type="nucleotide sequence ID" value="XM_047905721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHD8"/>
    <dbReference type="GeneID" id="71986451"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06573"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040339939" evidence="2">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="22943" checksum="BC2C9F2831F442D1" modified="2023-09-13" version="1">MHFKHLTAALATLAVGGALAAPAPVSGAALEARGKKDDFKHDGDWWDDKKLKARDDDDDHKDHKDGKKHKDGWNDKLKIRDDWDGDFDDKRLMARHEDWNWRKGSKGWKDYGNKLGKYNHDKRDNDDDWREHYNEWKDNVDNWFDDKKIKARDDDHDDDDDHKKKKEKYGRHGRYGDDDGRNRWDQWDDDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIE5</accession>
    <name>A0A9Q8LIE5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NAD(P)H-dependent D-xylose reductase xyl1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06085</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-xylose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762332.1">
        <property type="nucleotide sequence ID" value="XM_047905233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIE5"/>
    <dbReference type="GeneID" id="71985963"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06085"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032866">
        <property type="term" value="F:D-xylose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042843">
        <property type="term" value="P:D-xylose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19115">
        <property type="entry name" value="AKR_AKR2D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044487">
        <property type="entry name" value="AKR2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="10">
        <location>
            <begin position="63"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="9">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="365" mass="41131" checksum="FD3D9E4898E25B23" modified="2023-09-13" version="1">MSLSQAIRRTATLFSRSSNSSPLRQAAIQRLSSLSNQITSRNYAAMSAPTVTLSNGRKMPLVGFGLWKVTNETCADQVYNAIKTGYRLFDGACDYGNEREAGEGVARAIKDGLVKREELFIVSKLWNSFHDKERVKPICKKQLGDWGIDYFDLFIIHFPIALKYVDPSVRYPPGFFDENDKLSLSKAPLEETYHAMEELYDEGLIKSIGISNYNGSLLLDVERYAKHMPQTLQIEHHPYLVQKDLLELCKSRQIAVTAYSSFGPQSFLELNMQKAKDTPLLFDHSAIKSISEKHNKTPAQVLLRWATQRGVAVIPKSNNQGRLAQNLDVCSFDLSDAEIKQISDLDQGLRFNNPLNYGVQVPIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIF0</accession>
    <name>A0A9Q8LIF0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762433.1">
        <property type="nucleotide sequence ID" value="XM_047905369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIF0"/>
    <dbReference type="GeneID" id="71986099"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06221"/>
    <dbReference type="OrthoDB" id="3856067at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="27129" checksum="41B605027F544DE4" modified="2023-09-13" version="1">MRLAMIRRRDEKAASAIPAVFNTTELLEKILLRTDMKTLLLAQRVCRKWKAVIGASSTIQKKLFMVPVSNIEEAFRLGILRPPPFNAPITRHAPKRLGLPHSFEEIDLLGPMFDFTWHSGNFDILPNPMLDFTWTLGYINIDQKAMRGSIGKRIKSKLMTVLRNRRQRMCEPSWTRMLATQPPRREIRVLHYDLWPLPQTVRVAFFEWVPVMWGNGIAVEDAVIEGLHRFRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P354</accession>
    <name>A0A9Q8P354_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AFG1-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755723.1">
        <property type="nucleotide sequence ID" value="XM_047899384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P354"/>
    <dbReference type="GeneID" id="71980114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00236"/>
    <dbReference type="OMA" id="ECYDRRV"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF26">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="429" mass="47702" checksum="33AFEEEDF93DBC80" modified="2023-09-13" version="1">MTSSALQAAYKSLIQRGRLVTDPHQAALVTRLSKLQNDLLSTNNATYIPGQPAGTPQGLYIYGSVGTGKSRVADLFASTLPAEVTKRRIHFHEFMNDIHHRLHQARSSPAYRGDPLIEIGRNIHAESRVLCFDEFQVTDIADAMILSRLFSSIWQSGGVMVSTSNRHPNNLYENGLNRDLFTPFIKEVQRRCEVWEIGGKDDYRMRSLQDADSDQARLQTFFTDAEAFQGSFQQALGTSKLKRVPLQVYGSRMLEVQAAIEDERTTSAEKSKRFAMISGTFAELCEDSLGSADYHALCSSTDTIFISGLRRYREDEKDFVRRFITMIDLAYEMKTRVFCQSEVPLGEVFTNIVPQYLKKSIQGMRVKGEGGASSSMMSTFIGETEWSATGLVEASLATGGAGETDVGFAIGRAISRLYEMGSNEYGTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3A3</accession>
    <name>A0A9Q8P3A3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755917.1">
        <property type="nucleotide sequence ID" value="XM_047899856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3A3"/>
    <dbReference type="GeneID" id="71980586"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00708"/>
    <dbReference type="OMA" id="SPIHFFR"/>
    <dbReference type="OrthoDB" id="5396420at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="117"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="414" mass="45478" checksum="DE585743C0B2AA0C" modified="2023-09-13" version="1">MRLKEDKPQSPQEIESAKQEQLKTGKRKEELESASESVVGADRQEVGNHDDHIKELQQEGAKEKQKEHPEGKSVHKPLQSTASSSGAGSVLLYLPRKPSVEDNAEDASNISILQSTPNAHIVKINYRASDKAQFPTPIHDVLAGHDWVVSNLLVKRAITRPGRSEHVGKIAVCGELLGGGLATTLALTECRIGESGIIAAAVNNPITDWVELGGNDSDASTADQQLELQDLLKQRGALFRKPEHYYDPFASPILFFRSAGLDVPGHIEGKPMDDMDELSRLERMEYLHEHGIFADLVKSESLEDALVTVTRRKATRRYPSKTLGLRLPPFRVSGGKGSVLSTSTMEMVMQLRKSYERQIDAGVLRNVSAVAGTMSVDAMLQHEQHSGLGSWDATKCGRARMQQAAQWLAQKLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Z1</accession>
    <name>A0A9Q8P3Z1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00157</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756891.1">
        <property type="nucleotide sequence ID" value="XM_047899305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Z1"/>
    <dbReference type="GeneID" id="71980035"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00157"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF35">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63429" checksum="BFA790B1282317DB" modified="2023-09-13" version="1">MIRDHPSMVMTDPKHVDGDINGTTLERSETNEVEKDRKIDTVHGDVALATIASYSGSLDWSLEEEKRLIRKIDWMLMPLMFLSYALQYYDKVMLSQAAIFGLIEDLELDQGVRYSFGASIFYVGYIAGASPALLVAQRYPIERICSVTVLLWGVCMMSTAGCRTWQTLWIQRFFLGFLESGTAPMFMLVVRGWYTKKEQSFRMGLWWSAGGESECVTPCARSCNQGRLIFSATGYSVIVSPLINYGLGHIQGDLSSWQYMYLIAGAITILWSAVVFRFLPGDPTRARGFSERETYIAVARVRNNNTGVRNTHFKPAQVLDAMLDMRFWLASSSSILILMTNGPASTFPVDIVRDFGFTALASLLVLMPLGLVTGTVQLAVNYLATRYQNIRCLLIVVCQSLVVMAALLLWLLPRANLAGLLVGVYFLGPISGSYCLLMTLQIANTAGYTKRAFTSAGIFVGYCIGNIIEPLLFKMKDAPQYTEVWIIVVVTSIAGAVLAVTYRVICQWENRRRDKSGISEAADYAFEDDLTDRKVSHHSLDWLYRSFRYEADGYRSRIHSSAMSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4X4</accession>
    <name>A0A9Q8P4X4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757657.1">
        <property type="nucleotide sequence ID" value="XM_047901829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4X4"/>
    <dbReference type="GeneID" id="71982559"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02681"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040216496" evidence="2">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="140" mass="13616" checksum="DB73CC9EC06EFD22" modified="2023-09-13" version="1">MKYINAILPVALSFIVGASAQETSSTLMIPGPMEQSFTAISGTRTGGTMTTTSMPSMPESSTSTSASSGSQASVASSVVVNAGNPGGDSPPSTGPSAGDPGNVSQTGVSAAQNTGNPIVGAVRRQQALLLGLGVGAAFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5I7</accession>
    <name>A0A9Q8P5I7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758404.1">
        <property type="nucleotide sequence ID" value="XM_047902455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5I7"/>
    <dbReference type="GeneID" id="71983185"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03307"/>
    <dbReference type="OrthoDB" id="4153866at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08577">
        <property type="entry name" value="PI-PLCc_GDPD_SF_unchar3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039559">
        <property type="entry name" value="AIM6_PI-PLC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="52321" checksum="8180AA3AAECD45EC" modified="2023-09-13" version="1">MSSNGGIKAASSDSHALDSRTSMSEGSTVAAPYRDSFEDDEDLSSAVLEQSRSGVLARLLGALGMTVRRRKASYDYFEQNHLPEGLLKRHSPPRELRRCRRSYVAGVLKRALIALPLVVLLAFGVLHILQAVVGRAQLLWDVDTYDGYWPDWGKPGHVGAGLKDYPTDATRDVIPIRCHSHNDYWRRVPLFDAIHWGCTGVEADVWLFDEELYVGHNTASLTRNRTFRNLYVNPLVDLLDKMNQNTTFANTTGHGVFDEDPNQSLILLIDFKTNGRDTWPFVSKQLEALREKDYLTYWDGNQTHSRAVTVVGTGNTPFDLVTKNETYRDIFFDAPLDKLFENPKEHFSAPSLPQKSSQGTVGTSSSSDFNPGNSYYASVSFMHAVGFVWRGRLSSSQMNIIRGQIHGAQRRGLKARYWDTPSWPVGLRNHVWHVLMEEGADMLNVDDLRGAAVENWKARTHGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5X0</accession>
    <name>A0A9Q8P5X0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pumilio homology domain family member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PUF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758916.1">
        <property type="nucleotide sequence ID" value="XM_047902948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5X0"/>
    <dbReference type="GeneID" id="71983678"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03800"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000004">
        <property type="entry name" value="Pumilio homolog 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="10">
        <location>
            <begin position="518"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="539"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="575"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="611"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="647"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="683"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="719"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="799"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="176"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="864"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
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            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
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        </location>
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            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00060736"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00081811"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="953" mass="105501" checksum="C0DCE94D7402F29C" modified="2023-09-13" version="1">MSHGATSTSSNMAFTNTSRSFNSMNTTTNKKSTNGTIRATVNPWGSNSIWASTTGMMTNGLTSDATLRDNSVSRVTTQTEEPEAKTGSGSLVDSSVSEDWVNRNAWASKARHHTLGRSMQPNGRFADNSLQPQRSASNANTTATMPFSQNQMPYATRAPAISLNATTLPATRQSFSNGFSNGLSGRGDEPPHIYTKFNRPSDPAIKTKPDSAVGGSAGWGDQNTPSPIDERRTQFPFHRTTSGPTSRDNSLPPSRHSDVEPPSFSRVDYSRQSQRPSTNSSRAPSISSQRNGGYGMYMNGGDQLAMQFGQMNMNGDSRPSTSYRPMPSSNGYNGYSTSSMSRSSWQTNNGLARPQDSDDYDRQNMSFLGVEETTPRQTDFLSAYEIPALAARRLQSSAFDFRPGQPYNGNGLSQRAFEQQGVPRGSDWQNSSNGSLAMNRRTPVVPEQQAYLDPRTRQLMAAPLPVQSPYAATMYDQYGFPAAMQYAGIPPYMNMMPMCIPGIDVPNGAREDPSGDGVQSALMYEFKSNTKTKRYELRDIYDHIAEFSGDQHGSRFIQTKLETANSDEKDRVFREIEPNAIPLMTDVFGNYVIQKFFEHGDMSHKKILAKKMQGQVYSLSKQMYGCRVVQKALDHVLVDQQQQLVAELKGHVLDCVKDQNGNHVIQKAIERCHPNTIAFIIEAFAGQVQSLSIHAYGCRVIQRCLEKCDLPQKSMIMAELMNSIHTMISDQFGNYVVQHIVAHDEGACRREVLDIVMNNLEGYSKHKFASNVVEKCLEKSGEQWRHQVVMRLVQNSQRRIEGESPLVLMIKDNFGNYVIQKLLDTLNQQDYMMFQEVIQPAVTHAKRTGCGKQIMSIDKRMHKFDPPRNGSMSSATGGAMANGRDIRPTYAPHYATPPFPSSYTSAANTPPPLIADTPQSSIVPSINGDAVEGAMNKSRQGSDQSNDHTGIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6C1</accession>
    <name>A0A9Q8P6C1_PASFU</name>
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        <submittedName>
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        <name evidence="2" type="ORF">CLAFUR5_07995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="10"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="26926" checksum="1C648D4CC7A51BFD" modified="2023-09-13" version="1">MAPTTIVSVHNPECYVKVYTPLQHHGYNTVRVHLASIDPSHPIHDWSEDISRIRSAIEEAANSGHNVLVVGHSYGGLPSSEAIAVLDLASQTSANLPGGVTHLFYCCSFVLSEGQSLDSAFASAVIPWYDVSADKMLYKCKTPIEMFYNDLPEEEAKAAVAMLRPHAFQITFSKVTYAAWKHVPSTCLYCTADQAIPYEVQKMMVEEGAKGFGIRTETAEVSHSPFYSKPEVMVDVIRRAAGEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Q8</accession>
    <name>A0A9Q8P6Q8_PASFU</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="24956" checksum="C837AD112DF1C1C4" modified="2023-09-13" version="1">MSTIHVPEAEAVRRIQDLLPTCQNDRPRVAANKAACSCYTACTNVSLIPAPTILSEAHGQEWEHLHLPTLQLSSELAVSAQPPRLWPDASNTSWLDWPYQGNVVALQSSSSSSTDTTRHRPNIDTTSRNMSRPSQQGQFDTLKQELTHGSPVKGDAAADVVKTATVGAGAGSDVSGLGNAIGAAVTAGVGAVDIKANHDFKKAIVENREAGNFYSDPKQNHSYTEDPAFGGQGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6U0</accession>
    <name>A0A9Q8P6U0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6U0"/>
    <dbReference type="GeneID" id="71987888"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08010"/>
    <dbReference type="OMA" id="GDYRRWP"/>
    <dbReference type="OrthoDB" id="5389892at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF1">
        <property type="entry name" value="PAL1 CELL MORPHOLOGY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="44530" checksum="34E1B8201769DCCE" modified="2023-09-13" version="1">MSAAVDSKTAAAYLIDPMNAPEPSHETGPGTHFGSTFAPAASSSNAPLSASRTSIGSNNPFRDSTEKRRSPKQSPPLEKGGASSHARHVSSGSRGSRGSPPAQFPAYRADAFGDYNDTRPRRSGSGGRPPPSYEEANSGNNSPNQKGHRRRTSSLSARYPGDDSHKPLDVLRRDSKKAYRSPHLKKHHIPGADTVDRLDPAIGGKAYHHEGPYDAALLARNTSYRNSPVAALETSNQEALKATPRENVQDALERHKPLDGVAVVPPGMPDRFGRVYNYEEGADLMHEENNDGPGYKRWPDKDYSPDDLKGKGDTFELDRALRAHKISDDGGIEMQDGRNLRKSYDQQQRAGAIDSRDPVEIAGGQDKYVEMEFAHTRDADARVKRSGSLRDGLKKRIGSLRRKHHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6X8</accession>
    <name>A0A9Q8P6X8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450 monooxygenase orf4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759859.1">
        <property type="nucleotide sequence ID" value="XM_047907058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6X8"/>
    <dbReference type="GeneID" id="71987788"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07910"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF231">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="519" mass="59176" checksum="BBF49CEF86166680" modified="2023-09-13" version="1">MMSLAQAFFFVPIVLVGYLTLKTIYRLYLHPLSRYPGPKLAASTHLVEHYHELFNGPGGQFSQQYRQWHDTYGPIVRITPNELHIRDATFYETLYSPARPVRKVKNFGYRFNNEHTAFGAEDHALWKERRRQLDPFFSRKRIGNYVPNMQMKMNLLMKRLGQEYVGKVLSVTRMWECFAADNVVSFAFDRHYDFLKSPGFVSDVNEAVANMTGLTHWMSFDAVAVVVRSLPVGLVVRLVPGLRPVFEFWEAQEKQIKEVLDNYANGEKMGDTLFSSLLENGLADREKHLIFERLQSEAKSIVGAGSETTARSLSLATFHILDQPDIHQRLREELTNAIPDATVMPNWNQLSQLPYLSACIEETLRLSYGVSERRARAYDGGALLYRDGKQEWAIPPGTFVSMDNYDVSHDESIFPDSFSYIPERWLGNPKAPDGKLLNRYMVAFGKGARSCVGLQLAYAQLYGGLANFFRSELSERAEIHESSKADLEMAMCMFVPRPEPGTKGVRVLLHGKAQTVDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P711</accession>
    <name>A0A9Q8P711_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_08305</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="5"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759773.1">
        <property type="nucleotide sequence ID" value="XM_047907453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P711"/>
    <dbReference type="GeneID" id="71988183"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08305"/>
    <dbReference type="OMA" id="IRDYVYC"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009220">
        <property type="term" value="P:pyrimidine ribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000242">
        <property type="entry name" value="Dihydroorotate reductase PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="169"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="678"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="454"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="582"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="530"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="640"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="652"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO15407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="734" mass="78602" checksum="60BDC015AC98DABA" modified="2023-09-13" version="1">MLATQRALGASTRLLRQTHAPNGPQWRSLQRQSPRHLSQHSARQTRSIAVISRRAQSTTTDAAKATADSAAKASAGAAKHTARATASGGSRVIAYLYGTGLVILLGFGFLYVTDTRASIHQYLVVPFVRFVHSDAEEAHHAGIRYIKGLYDFGLHPRERGNKDQELADLRVEVFGHILDNPIGTSAGIDKNAEVPSALFALGPAIVEVGGATPLPQEGNPKPRVFRIPSQNALINRYGLNSDGAEHVAMQLRERVRQFAYSHSLGLSAESERIVLDGEADVPPGSLVPGKLLAVQVAKNKTTPDNDIAAVARDYTFCVDHLAKYADILVVNVSSPNTPGLRDLQATAPLTAILSAVVNSAKSVDRKTKPAVMVKVSPDEDSDAQIEGICSAIWAAGVDGVIVGNTTKKRPDPLPKGYIMSAHEKQTLNEMGGYSGPQMFQRTLDLVSRYRTKLDQAPRDNSPSKSLTQKYPAQAPPVDDCKPAPTTKLESANTIDETVQRDAARLKPLTAEAEQESKQPLVQIPERHSSQDAAQQSNLIGQGSRSEVPPTESSSAFAEGINREQVLGGQGPRESAQAALDKINTHDGTDVSEKRYASATDNVPAKYKPKPAESESIARKAKDAVAKTKETAKDTLNKIVPSTDPSSTTSPTAVDTKSVASQTPKTNDLPISDPPAKVIFATGGITDGEQCLQILNAGASVCQVYTAMMYGGVGTVTRMKEEMRTAIKQQNSSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P772</accession>
    <name>A0A9Q8P772_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
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            <authorList>
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                <person name="Chen L.H."/>
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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761468.1">
        <property type="nucleotide sequence ID" value="XM_047903042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71983772"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03894"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056625">
        <property type="entry name" value="SH3_CYT4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056624">
        <property type="entry name" value="WH_CYT4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF65">
        <property type="entry name" value="EXORIBONUCLEASE CYT-4, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23214">
        <property type="entry name" value="SH3_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23216">
        <property type="entry name" value="WHD_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1671" mass="188192" checksum="496E864E73933D2E" modified="2023-09-13" version="1">MLASRGGAVGKSSKDAYVCLSCRLTTQKRRHAGSKARYGEAAATSNDDVTGAKETELATQSGQRHARLQHELKRRRPAARDEEVRTEAPTLPSGASTTKEPDTNGRLQQKRGAPKTQQWIDAADKAYSAHTRRMNTAARYFVEHARKQHANLATRSNNDWWLAREFLKYPQYCLADASTEVLLSSIASKVGRSTNLKGALLGDNDYADDESLGELALNALAPSDNNGTAKVVEVFLPRLGADDLPWESGGRLDICTMIAMNKISRPFSRQISQANKKRNSDPAHHFVEYMRKRCATFKPYGNRIPYLLNDVGLYPQYRLDGLSDRSLPALHKVQGYLESFWQSISQDTTPPDEIDSRMVEVLRSLSLDVLGQDDHAFWSQSRTTSIEWWAQQYSRWRSPEKLLPAVLMSPGRLISKGPRFAKHESMKSGQHMDHGDPFPPPAASRFVVVKDPRSTETLDRTIDEHLNEPYMPSSHATDDTNTEPFELRDATTASPMEMQHYTPAAFDIPDDESTSTLTAFGQPSKVASRTVYSEEGQPASKHLDDETMNALAALEEAASAAAVPAKTNSPWSQLRQQARRAPTVPTSSTLSGFAWQGSHLSTQPPSNSGTGGNSTRLYHSSMRTFQQSAIGTPSGEQVRPQTPLIRFTTGPESHFKIPSADEAENPNGIRTQLRKWQELHGNEDNTPEVVEQDDHADVDEPVNNLTRLPDDSASRRQSQQDEEEKESFARFIDAGKEGYDGSGDDSGRFLTMGDLVEIEYLSSERESILAVYVQSVHSGRKEAQFFDMQGRWRHLPEKTIMYSIPGWISPESVKPLLEYLPTPDDTRDMDALLERAYIEDLSVPREVAAPLVKRMVDFYNESQDIYRKNASTLDDAHNILAHDTDLRYGSLVSAATTLLRIPSDKLPLTALFTVRKALTHGGFAFNIDRRSHRLTGYMQIRSKEQVKIVENVREWVRQWQDDLAQTAGMNERQLDRRRVAKGAQHVYGFLEKARAIVMKNRETRHLAPHRPEAQHTTNNIGISKTRLPITETSDSVKLHHGSEFTADETEIIRFMESWACNAMFFGLPRIESLPPILLQATGLYDKQRLGVGTGFVFLQELGTIMPYENRIRFDQHLLLPSSQHSKPLQNLMTSLISMRDKHNFNDSMADLRHDWKDLPVYCIDDATAHEIDDGISVEPAGRGADGRKQHWVHVHIANPTAFFSRNHPLAKMARHMGETIYMPERTYMMLPRWATQRHFSLAKNRPTLTFSAKMDEDGKTIEQKITPGLIRNVISLTGKEVQELVSEKDVAESTPEIVLTVGGDPPPSRGRKSSVSDVTEININDLRLLRNLAAKRANFRKNNGGLFFNSYNPDVSVWQSWKTPGLAWDHPYRRGSRIVEGDPVIQLRTTGFRNWFTPTSQPAEILVRECMLLACEIAASWCSERKIPVIHRGTVSDPRSVDTRNAWKEQMLPAMREDGSFPMHLGVQYIKSIGTTVLATEPKRHVFLGMDHYSKVTSPLRRYGDMILHWQIEAALRHEAETGVSLATAPDDKYQPDRGFLPFSKPVLETVMLGLQPRESIITAAKTKAELFWTCMLLFRKHHFGEDGGLPFKTLRMFIPGDVGQMRMNETPGFCIELATNLTLYDPRKYGLPEPRQGDVWEVELDCVDVYIRASFAKPLRLIGREGAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8R6</accession>
    <name>A0A9Q8P8R6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phenylacetaldehyde synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761648.1">
        <property type="nucleotide sequence ID" value="XM_047905651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8R6"/>
    <dbReference type="GeneID" id="71986381"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06503"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="552" mass="61234" checksum="18B62DC9AFB99582" modified="2023-09-13" version="1">MAGPTDAANGHTNGTSKLDNRTVPPLGMTSSQFLEAGSSVLKDIEEYYTNLHSRPVVAQIEPGYLSKLLPASPPTEGETWKDIERDIETKIMPGVTHWQHPKFMAYFPASSTYPGILGEMWSAALTAPAFNWICSPVVTELETHVLDWIAQIIGLPEAFHSKSTGGGVIQGSASEAIVTVMIAARERFVRRQIEQEGLTDPEEIEDRSCEIRSRLVALASDQAHSSSQKGSNIAGTRFRSLPTRHGDAYALRGHDLRKKLQDLESKGLHPYYLTISLGATSVCAVDAFAEIAEVAKDYPNLWIHVDAAYAGAALVLPENHHYSTSLSFVDSFDFNMHKWLLTNFDASCLYVQNRNSLTSALGITPHYLKNEFSESGLVTDYRDWQIPLGRRFRALKIWFVVRTFGVRGLQEHIRHHLALGDLFADLVRSRPDLFKILSPPSFALTVITVNPRKSSPLHLTNGAQGSDPRPFEETQSVIDPKTNGDVDLKAGNEVTEKVFTIIDKQKEFFLTSTVVDGVYAIRIVSANPLAEERYVRQVFERLVETAEAVLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P966</accession>
    <name>A0A9Q8P966_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762098.1">
        <property type="nucleotide sequence ID" value="XM_047905501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P966"/>
    <dbReference type="GeneID" id="71986231"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06353"/>
    <dbReference type="OrthoDB" id="3813486at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="275" mass="31184" checksum="F1BDDE321A1002E5" modified="2023-09-13" version="1">MAEPPQRASLLGLPRELRLQIYQHVFDIDLHHKVLLQWRDTHTAEHGFKSVPDLNHGDKLTIPWLQLMLTCRTAAVELRALMQESSFLEQHNNGTYTLDLEATRGGMTLGPTTWRHIPCAPSQVQCLEAYYNASRGFQAWGVGGPHGITSGLYQTLNHFVHCGPRFDSERMLPKPSHLKELRVIVVEREFRGEDENPSYGLSERDTDPRTTLYALGSIVGQIVRTGVLKGFVDDIHLSCDGEVLNWSPSIEDGEGIPEYWNRYGFDWGMALYEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9A3</accession>
    <name>A0A9Q8P9A3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762425.1">
        <property type="nucleotide sequence ID" value="XM_047905039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9A3"/>
    <dbReference type="GeneID" id="71985769"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05891"/>
    <dbReference type="OMA" id="SHANFVE"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35814">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35814:SF1">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="16983" checksum="FBD82CBBD361009D" modified="2023-09-13" version="1">MSNIDQPSPAYIINIGLNLPVTSSFALPLAGYYTWLQYRVISNRIRAKQSIAQFDPKSATSREPDRLLAACRAQANFAENVPLALTISALVEANGGSKRVLTAALSVLCVARVLHADFGIMAKNNMDRGRPVGFFSTVAVVLGMAGYGAYLARGSWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9B9</accession>
    <name>A0A9Q8P9B9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Mitochondrial inner membrane i-AAA protease supercomplex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_06167</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762364.1">
        <property type="nucleotide sequence ID" value="XM_047905315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9B9"/>
    <dbReference type="GeneID" id="71986045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06167"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141164">
        <property type="term" value="P:mitochondrial protein quality control"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000002">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000175">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 18" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="312"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="718"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO17998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="762" mass="81298" checksum="827664B6F001C7F8" modified="2023-09-13" version="1">MATTTTMGSVLARGQAIFAVRPAASILCHLPRGTLPLSSLSPASKCFSAATRLGPLALRAPVRTSFVGFSQQRTIFGGGGNNSNSNSSNAQPNRNLLAHMEQQANNNPSSATAQNGFYQALLRANMPEILVERYNTGRYATNAATDQAYQKALERLGAAEVGAGGLGAMAGRIPAGNSNTMSSEQLQAIGQAVSAKTQGGNVSISRQGSGAKSEPLYVVVDESMGSTIFKWVRFFLVFGLVAYCSLVVFTLLIEATGVLKKVGGAKDAEAKPELQTTKFSDVQGCDEAKDELQELVDFLKSPDQFSTLGGKLPKGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEVYVGVGAKRVRELFTNARAKSPAIIFIDELDAIGSKRHERDAAYAKQTLNQLLTELDGFSQDSGVIIIGATNFPESLDKALTRPGRFDRNVNVPLPDVRGRIAILKHHMRNIKFDPAVDAATIARGCPGFSGAELENVVNQAAVRASKLKQQKVTEADLVWAKDKIMMGAERRSAVIQQKDKVMTAYHEGGHALVALLTEDSTPLYKATIMPRGHALGITYMLPEMDQVSETKRQMMAQIDVAMGGKVAEELIYGADNVTTGASSDITNATRIAYSMVTRAGMSESLGNIDLANNYNKLSGETKKQIESEVRRLVEDGRKRAVDLLTKNREGLERLANALVEYETLNKEEIEKVVRGEKLTDKLKVDVSTPVKMPEPGSFLPPPPPPGVPVPGVGSGSPDPPSGGQVAGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K5</accession>
    <name>A0A9Q8P9K5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762725.1">
        <property type="nucleotide sequence ID" value="XM_047904888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K5"/>
    <dbReference type="GeneID" id="71985618"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05740"/>
    <dbReference type="OMA" id="ISNNCAY"/>
    <dbReference type="OrthoDB" id="2098436at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF5">
        <property type="entry name" value="RESPONSE PROTEIN RDS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G12490)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32009" checksum="9C80C0A78195B4F0" modified="2023-09-13" version="1">MLGWDAAPRQCTYDYPFTTVREYIDFMQKLTRWGESGNRGFIGHLDSREVATLLVQAEAIEARQQSVFRQMLGLHPMPIWFAPGIPQSWHWTLLSQYISSCPENNTRVAWQNFPNLYVANQPNTNRINANNTEEDELTTGSRTGDPSKSSIVPDDDNCLLTNQTGESCVAAISQNRDIPLSYPGRPIELTWDAPGIATGPNNSYVTSTTAGEPQFVAWLGQYNLTYTPLEKTGNASGTTYQPAGDVFQGDPALNGTAFIALTDTDQLFLTPFNLSLIHPHVAALGLYQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9N0</accession>
    <name>A0A9Q8P9N0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aspercryptin biosynthesis cluster-specific transcription regulator atnN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06007</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762487.1">
        <property type="nucleotide sequence ID" value="XM_047905155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9N0"/>
    <dbReference type="GeneID" id="71985885"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06007"/>
    <dbReference type="OrthoDB" id="3598904at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="660"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="715" mass="80738" checksum="7F53598A8F22B08E" modified="2023-09-13" version="1">MTIPVVRKRAKKPKTRTGCKTCRQRHIKCDEERPACRRCRISGRECAGYDAPRPETCRSQAVLLPKGSQVASVKLPTLYPVEVNRGPSMITTLGMSNVEAYAFDFFRLQTVKQLPGSSWTLSWERLALQMGHHEPAVTHAAIALGSIHRALTFDAFRGPAGIDKEQHGFALCQYNKAMSYIRGYIENLGTGCSDNDVEVVLLVSLLFFCFEVLHSEDARATIHLRTGLRILYERIRDKSPPATPWGDGELKRTVMMKPMPQSNMDVILQTFVRLDGDLTIVGEDEPYLFPVCQERLPSAFYSLDEAMVHLDAIASKTHDFCRDIVCLTDQEIISKRDDYDSLDDDMRNCLACAASRTIDLQTDPDLLHRMEQIKHELTGWMTALSSYTVRAEKETQHILTQVHFFYVYFIVSTWRDPSEVFVDRFDDQFHHILTLIEQYVDLHFDGMASPNLQEQPGQYSSATTRQAFTLGTDLVPCISMIAFKARTSSLRRRCIGLLRSINLQGVFDSYFLASFIQLICDLEENRAGDLTGKPEGEDFHCHEIPEAARFVEIELSPMQHASEFYKADMGRLVYCTSNEHGDLSVHEDWFNVIRPATPITHDYQGRADSPAELFWNSNSNNARRENGGPETPESLGPWVDAQTVHSRRISPISGAPRNGYRSTLTSNSRPQFPREYPIEHARPATLAASGDAGNPQSRGEEATAPPRTQYERPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Y9</accession>
    <name>A0A9Q8P9Y9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase phnG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762970.1">
        <property type="nucleotide sequence ID" value="XM_047905931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Y9"/>
    <dbReference type="GeneID" id="71986661"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06783"/>
    <dbReference type="OMA" id="CAHHFLD"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="92"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="566" mass="61034" checksum="5EB9C8648FA7C9B1" modified="2023-09-13" version="1">MSNYYPDASPAGVPSPAHVPATGKPSIPFQSAQLQQQTLGPQTLPPNFVSAPTSPPPQTPIPAQPHHQRQPTIASYQSGSEAGATSSQEPLNIIILGASFGGLSCAHHFLDYTIDRLGTSSAVRPYRLIIISPSTHIYWNIGAPRALVKGGLIKHEDTFIPIEPGFVRHRGHDWTIVQGKAIDWDPEDRSVKIECLNLEAQKRCSYLLPKRGSKAFDTNASVSSLPTVQSLPYHALIITTGTSAHSDLLSLHGPHLHTADALNAFHRKVAAAKSIVVCGGGTSGVEVAGQLATLLNYKSHIGPFKTKVPNPKSITLITGSDRCLPGVPNPKVGTIAEKSLLKLGVEIRHNVRVTDAKEWFDQTGATRIDLSDNTQLIADVYIACTGVGPNSAFVPTYLKDDKGYIAMNHKTMRVDAAGDRVYAIGDVASYSYNYVPDVYAAVPVVMHNLLNDLIAHELSVSNPYGGNDDYIEQLVDEEYVQRENDSQLCPISRYGGAGMLLGNVLPKVMVHLLKGHDYRVCKAKGVVVNGGNPYATPIPGNKYSSEAYDDQGYRKRKIGGFGKLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA20</accession>
    <name>A0A9Q8PA20_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763013.1">
        <property type="nucleotide sequence ID" value="XM_047906560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA20"/>
    <dbReference type="GeneID" id="71987290"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07412"/>
    <dbReference type="OMA" id="EHEANNM"/>
    <dbReference type="OrthoDB" id="3910509at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="25464" checksum="30344D5902619F02" modified="2023-09-13" version="1">MPSARPDPFTTSSNAASHPASRSLRAQPSQQSLSSNASAASTRTRQQRELFAPALSRRPTSRTTPRVADEVLADSDEENQEREPIVHRPRQALRRVRHRSPEGRLARARPKQQVEEADIVNRDATGNFLMKAPHGSKTPEWEETAEEHEANNMKHMDAYYANVARKYFASGAHLGMRTGRQSEPDFERDVGDMMFYLKDEVMRKLDNERWLYEPVDRLQPPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAF1</accession>
    <name>A0A9Q8PAF1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763191.1">
        <property type="nucleotide sequence ID" value="XM_047905913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAF1"/>
    <dbReference type="GeneID" id="71986643"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06765"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000071">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000138">
        <property type="entry name" value="HMG_CoA_lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF17">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01062">
        <property type="entry name" value="HMG_COA_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="627" mass="67267" checksum="4E489F047592393D" modified="2023-09-13" version="1">MMAFVLNNSLRRLHRVGRAFSSASVERLRILEVGPRDGLQNVKAQIPTDVKIELIQRLAVAGLRNIEATSFVPPKWIPQLADNRKVMDVVGPWAQKRDVELPVLVPNMRGLDNAIEAGASSIEVFASATEGFSKANQNTSVEQALDIAASVARKALSSGLAVRGVTSCLFADPYTGATKPEQVLYVVERMLAMGCYEIGLGDTLGVGTASQTRALLEVLLERVDPSKLAGHFHDTYGQALANVVAAYDLGIRSFDASVAGLGGCPYAKGAQGNLATEDLVYMLESSGIKTGIDLVELSKAGDWIASRVGVPNRSRAGAALMARSVDKTTKSVPTRTEEMSGRSKVVEVAESDASDTVWKAEVSTGDVLVYRCGTAAKIVLNRPQKSNSMTGNMLESLTKLFKDFSQDPSIFHIILTAKGRYFCTGMDFGPSTDRTSTEGGYYSLVKGLFTAIEECKKTTIALVDGPAFGGGVGLTFACDVRLVSRSAKWSLTEVRLGLQPAIISRFMAREWGFAFFREACLSGRGVSPDELFRIGAVHSVSDDTAALDVAADKYLSQLGRCAPGAAAKCKDLIQLAWSDAGGLQQEALIEERFGTMMKPGSEGEYGIAQLLKKEPADWAKFALSQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAU3</accession>
    <name>A0A9Q8PAU3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Structure-specific endonuclease subunit SLX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07520</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763403.1">
        <property type="nucleotide sequence ID" value="XM_047906668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAU3"/>
    <dbReference type="GeneID" id="71987398"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07520"/>
    <dbReference type="OMA" id="HNRGCDF"/>
    <dbReference type="OrthoDB" id="24645at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1440.10:FF:000006">
        <property type="entry name" value="Structure-specific endonuclease subunit SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048749">
        <property type="entry name" value="SLX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050381">
        <property type="entry name" value="SLX1_endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208:SF10">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21202">
        <property type="entry name" value="SLX1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="10">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="323"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="44551" checksum="34F62D2B6DA0F911" modified="2023-09-13" version="1">MEKGIAPIPALYACYLLRSIARHSSLYIGSTPHPPRRLKQHNGDAGGGAKRTSKDSLRPWEMTCLVTGFPSKIAALQFEWAWQNPNLTRHIAPDDRITQTKMTSRISPKTGRVRKRSARPRLSLTDRLANLHLLLRANSFERWPLKLTFYAEDVHRVWTKLPGVSVERLRTGIDVVMDESSRGLPTAPKADDPALPATAVGIQAVDVGYSSFKPQLEKSQVLFSGETSHDCAVCNKAVPSSGAVTLICPDAACNATTHIQCLSIRFLQTTNYKDAMVPTHGHCPSCGTKLQWVDLVKELTLRMRGEKEVKALFKPKRARKGTVAKSASVVDESSAEDDDPLDMVLDEEDDHFHELPESSDDEAPRIRSDPSPGHTAFKRPKPFTTFSEPVIDDSDPDEVELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBK6</accession>
    <name>A0A9Q8PBK6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763841.1">
        <property type="nucleotide sequence ID" value="XM_047906811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBK6"/>
    <dbReference type="GeneID" id="71987541"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07663"/>
    <dbReference type="OrthoDB" id="3231000at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="28137" checksum="82E69467C3D9D663" modified="2023-09-13" version="1">MSKEDLELVRAHPKLVGMQAYRLTLHDWLVTLKFMQTQLAKVEWEFEMPGHGQNPVDHWAALKKLAPWERHAEFREDMVNDMRIILDLEPNTHGSVTLLALKQDVVEIRKSIVAIRHRLALIRDMITTNVGIEESRRTAAALEQNRSIGGLTILATIFLPLNFATSFLSMSSGFSVKSNTFWRFFAIGVPLLTLTLLAVGLMSWGLKTLAFISRRLSRAGVRVRGVVSDVCWAVCWPARDVFDTVVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCZ2</accession>
    <name>A0A9Q8PCZ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764560.1">
        <property type="nucleotide sequence ID" value="XM_047909441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCZ2"/>
    <dbReference type="GeneID" id="71990171"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10293"/>
    <dbReference type="OrthoDB" id="5414285at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="27621" checksum="67547E86E1A9D635" modified="2023-09-13" version="1">MAISGWAVFLIILVVVVIAAGGGYVGYTHSRARKLGLPPPNLNSFSKNSQQDNIYRAPAPAPNGIKDWVVDKWNGIRGSGSGRTAGGAYESTSYDAGGSRRSGGRRGFGPLDPDEAWDARVDNEASGYYEEQELGLQDPGHGPYGGSGYGHAHSDSVGVGGIEAGRGRSRSRQRELDERYDEEVHGGGAKLNPFGNAAEASNMSLRSVSPRPDVDTGYKGATGGRGPSAHRKNQSSLHTNGSNENSPTERRSMFTEDLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD10</accession>
    <name>A0A9Q8PD10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764546.1">
        <property type="nucleotide sequence ID" value="XM_047909333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD10"/>
    <dbReference type="GeneID" id="71990063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10185"/>
    <dbReference type="OMA" id="HDAITIH"/>
    <dbReference type="OrthoDB" id="1022638at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="21878" checksum="E1A4256182F885AA" modified="2023-09-13" version="1">MSSDTASTEKKTKKKRYTSNIITLKPGEGHDAITIHEDILRDHSPFFKAALDKKWLDGATREIKLPDDTAEVVAAYVDWLYSRRLELDVPKDTKGRPEPEILALLLRQAEELGTWPSVRCVVAAYAGTPEGSPLRRCLVEIYAARMTIHWDFREGSYPVAFTMDLLRAMVKQRTVDDTKFYPRRETWFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD11</accession>
    <name>A0A9Q8PD11_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764589.1">
        <property type="nucleotide sequence ID" value="XM_047909849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD11"/>
    <dbReference type="GeneID" id="71990579"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10701"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="82"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="469" mass="51616" checksum="18BB1F0DD483FB5A" modified="2023-09-13" version="1">MGEIANETISNMALERTIYIGPFVHCESLTELDVAVNGMIGVDEAGKLAFVLRDAKGKQIPTQEGWEDAKVVRINARHGFFFPGFIDTHIHASQYPNAGIFGKSTLLDWLNTYTFPLERSFEDLKQATRVYNRVIARTLSHGTTTACYFATIHVPATNLLADICQSRGQRAFVGRVCMDTLGPDDYRDESAQHSLDRTKECIEHIRQIDPDFELVTPIITPRFAPSCCSDSLALLGKLQAQTGLPVQTHFSENKAEIQFVKAMFPDSKHYSDVYDTAGLLTSKTILAHAVHLTPEEITLLRNRKAKISHCPASNTALTSGAAPIRHLLNEGLDIGLGTDISGGYTTSLLAEAREAVMVSRHRAMIDGDEAKLSVEEALYLATRGGAKVVGLEDRIGGFEVGMDWDAQMVTFADVGDEIGLDLRDGPVDIFGSLGYSEKMEKWVFTGDDRNTLAVWVKGRLVHAREVIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV8</accession>
    <name>A0A9Q8PDV8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein alcS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11311</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764992.1">
        <property type="nucleotide sequence ID" value="XM_047910459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV8"/>
    <dbReference type="GeneID" id="71991189"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11311"/>
    <dbReference type="OMA" id="FMICATR"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="30739" checksum="E26CF05C5A706755" modified="2023-09-13" version="1">MSESSKDLENGVHKDYASGNGAAPEQQGSTSDLSQLLTNNTFSDEQFERMFLLPRNQGVVGGQRKTFATPTPLAIMGFSTGLTPLAAQLIGWRGAGGSGQSSVGATIWFGGMLLIFAGLGEFILGNTFPFLVFMGYGAHFLTFGTTFIPAWNAVSAYTSGSPYTGEAGSQAITPEFAQSYGFYPLSLCILSAIFLICSTRTNLIFFLVFVAATLGFGFAAGSFFQIGNGNMALAANLLVGCGSCFWAAAMLGWYLLIAMMIPIMELPLPSLPIVDLSTIVKPRKRKMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE59</accession>
    <name>A0A9Q8PE59_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Septation initiation network scaffold protein cdc11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765161.1">
        <property type="nucleotide sequence ID" value="XM_047910065.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990795"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10917"/>
    <dbReference type="OMA" id="ATSWGTD"/>
    <dbReference type="OrthoDB" id="7451790at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061499">
        <property type="term" value="C:outer plaque of mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902412">
        <property type="term" value="P:regulation of mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031028">
        <property type="term" value="P:septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
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        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566:SF1">
        <property type="entry name" value="PROTEIN NUD1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="617"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="662"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="802"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="909"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1061"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
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        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
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        <location>
            <begin position="197"/>
            <end position="225"/>
        </location>
    </feature>
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        <location>
            <begin position="373"/>
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        </location>
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            <begin position="412"/>
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        </location>
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        <location>
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        </location>
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        </location>
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        <location>
            <begin position="1061"/>
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        </location>
    </feature>
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        <location>
            <begin position="1078"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1829" mass="202205" checksum="9E55FEADC477684A" modified="2023-09-13" version="1">MSQDTQNVAPWLAGLGDDDDVSWDIPIPSDINISSASHDANSIQYGSTRNSRRKVSGPWGSVRGTTQKRRSPLSTLSNSNNNTQRRPHGLSKLTQSRSFSGASDTSVVQYDTVAQRSKSSSPAKKQQTLEWKRRLLQGRVGYGDQTDLFGATGLENIFAQTPADDGPKKATSSMSWLDRSAVAAMPSSPPPWPSQHDQSERYEEHENVEEGDRLGTVDEEHESRTTAEQYQNEDSFESNPYDLQDSEDPEIPGTELDQPSNVPYSSPDRPITDVAHDNVVGNRTMSGQTDLDDFSPVFVSKHTTMTGQVEYKALDSRLVKQFQKSTVDLRHPSQGQSSDDTLAEPQEPSIVEQSGFTDGPESEVLPAVPDLSLSENLPTGTPPTANLGENVQTRRGGWSAEGSFKEKPLSPSPSKTEPSIVRHQTSELLSPVDATSRNDRPATPSQGQSEPRSRSSGSPLKLFGPHDTFTSNRLLRRMSQLDPDLSQIRSDDGDEETRQHRPSAVRQPGFRNVSGNSFGSGDLSGHPFNAEITITSASDSDRADSDRSPGSEVPPPGSRAPLGFRFDDAPAAGDTFKLKRKISKRSEVNSKTSTLNTQYRYPTVEDASEAASVARRVDSNTAAGKRPPNSPFKAPTPKRRRTLHASELVDEVAEANGSYHSQLQEALSGSKRRASRNDRHYDIADPDVLAERKMLRPRNPTPSQRRRDKIEAEIREAAEQFAEQEPEALEAVMEQIESSMVSGTPPSIEQQANVVANEVAKFSLRVQKASGDYAERKRSVTTQDFFNEAVMVMRLIREKAGRQSGLGSVAESDQEAISEGDQSGQDLSSLRVSRPPSREAVSGWRPRNSQPTDARVISHLRRFQERDDTEFLAQSVISAHADDNDVPDVVVDEHSNIRIRGPMLMRDHHADEEHSRPSTQHSQQSSLASHSSQNSDATSTGRTVLSRKSENLGNLAPDAVAHLIGEQVGAMTYDRDRQQWVKARSPKKQAYGSFLEPPSNITSDDDPFREISDLPVDEHKEEEIRKASAQRRPSAVQFEGRPVSASGAELYMAAQIESRTTSQETVLNRPTTRDSKVSCHTYSSSDPSRYTAFASSQQQTNETRATSWGDDDLHRLAAQGKAQQQPLAYAAAQAALAIAHRNEATETLQGVVEEDESCMSSTGHGLHGHVSASLEDQTIEASLVDETGYSDGLAVEELESPKLRRALPTMPTNQPSSTYRGAARQMSLRRKTLTSRFNDAETHEQSELSFVAPLPGDRMMSVSLSVSRPMSKRQQGHVIEAPSSPAKYDPSFMLSDLPDFTIHEEDKERPSEKALAQRLARHAAAEVDDRYALAMKDMVKVLTDVKADEPYWEELKQLDLHDRGLASLHGLDGFCGRAQDLDVSNNKLAYLNGAPATVRHLIARSNQLSSLTPWSHLMNLQYLDISGNELQNLDGLSCLIHLRELKADDNNIQSLDGILHLDGLLKLRARRNRLQVIDFAQSQLDRLEELDLCDNGITAVQHVDFLPALRSLKLDHNKLLGPLRFHERMPKMRFVSLKDCELRHLNVTCLPGIRTLLLDQNCLSTVQGIAHLKRLDVISMRKQTLLAGQDVTLLEEDLVARTVHLSGNSLPMISLPHNLLSVQHLELASVGLQELPPDFGLKLPNLATLNLNFNSLKDIRPVLNINRLEQLLVCGSRLDRLRKTAITLSKLKTLKTVDIRGNDLTQPFYPLHACTQPITSVIRRSACGGMEDDEDTKAEDGESMKYLLPPLDPGADRIHYERMDEDAKLRRKVYHAILANGCPTLEFLDGLAFDKKGAMARDATWHKLVELGVLRKSGAVGLKENEPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE85</accession>
    <name>A0A9Q8PE85_PASFU</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">CLAFUR5_11223</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_11223"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="91" mass="10037" checksum="D8B08F659A055EA1" modified="2023-09-13" version="1">MPPNEDALTVSAAARAFKRTLFSTSWTSQHYRDPFHMTYIMSGPAEEAASKTALAKVFGGALSNALFSELTVVCGDRQWLCHRIVLCRVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE93</accession>
    <name>A0A9Q8PE93_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">O-acetyltransferase PaAT-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE93"/>
    <dbReference type="GeneID" id="71990811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10933"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
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        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="43"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="56991" checksum="CB11FAB21640D518" modified="2023-09-13" version="1">MDLQYNKLNLSLPHIFWTLVDFLRPEILTRRKVASERRGSSTSWLDGLRGVAALTVCFMHLSVYVHPGMELCYNADLGFNKRNDHFVTLPFIRIPFTGGHYSVGLFFIVSGYVVPRRLIKLLHEGKKPEFIDAVNSAMFRRPGRLFLPVIWSTGILMASWHIFGIEMPWGSQQTNIVWETFNWFRDMMYFMFFFREKLLFSWYNFHSWTIPVELRGSMFIFVWLFTMHQVANRGRILLTVGMTYYLEILSPGAWYACFFAGMLLGEFDLLAEEGDPVDLPWNGLTRYFRKNKRATQIIAHIFLVCGMFLGGQPSADWQKPEEILGTCPGWITLSKLIPKAYTEITDMPTYRWFYIFWAAFLTVVAINNIPWAKWIFETAPAQYLGRHSYALYLVHGPLIGILSERLFFLTGVKSPTDLASFVRFGRLHNKWHDLPWWPLPDGGPSGLEPNFLFCAAISIPIFLYAAEIGTKTFDAPSVKVSSWMYKKVRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEA3</accession>
    <name>A0A9Q8PEA3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765193.1">
        <property type="nucleotide sequence ID" value="XM_047910377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEA3"/>
    <dbReference type="GeneID" id="71991107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11229"/>
    <dbReference type="OMA" id="NINHAMA"/>
    <dbReference type="OrthoDB" id="3647961at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="391" mass="43831" checksum="741C991ABBCA1DD2" modified="2023-09-13" version="1">MVFLTLALPSAVLAVKAPDSKKGMTFEIEKVFEVDFSTDAQGGCKSYKELLTNSYYDAIVALTGALNAIESVSQVTKKSKDHDPIAKKEWLRVRQTYEKVFGVDPWTPAGGLTKDVSPIRKTYDEYLASLQTPEKDSEKEPPKFTLRCEDDWLEWLEPTDPDPREAGKPDAKKFTLEKPREGQKAFPKGAFQGTNLEPSRSLMIRKEWVTLKNKKKPICGHDYAGLGPTGAMVDPPTGLIVFCKTPLVNKGVVATLSDLTSQIKVGAAIDLARFAGNPIWLHEFGHLLKNLRDQRALDKDGIKIKHPLGGYENVYHWEMTVNLAKCRVDDVPENPECYRMFAVAMYWNEWFWATGKAKKEPEAEGGMAGPSRMKRGSRMLRDLVEPGVIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEB6</accession>
    <name>A0A9Q8PEB6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_11262</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765250.1">
        <property type="nucleotide sequence ID" value="XM_047910410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEB6"/>
    <dbReference type="GeneID" id="71991140"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11262"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000269">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.40:FF:000002">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="399"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="29"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="826"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="918"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="900"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO20884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="937" mass="104104" checksum="C261DEA90011B527" modified="2023-09-13" version="1">MLISTRPANVCIRCAYRTRLLALQQRRLRSTHPDRDENSNGPILRYLDKDDGGHELRSGPPRGQFLPTDGLIRKHSGRPTRKYSGRGEVGRDDRRGGMGWGGREGENFREVLMARLNVIKDEVKDAPVLQQLAKDSKEEGNKQEGFGRIWSGFTTNLLNHEPRHRPFLGKPDGKDNVWEDLRNAYSTRSQRGLDDRIKYAFYGHVTGSRFTESDIRNQKTLADLRYPTEWYPATRLLHRTVHLHVGPTNSGKTYQALQRLEAAKSGVYAGPLRLLAHEVYSRMVAKGKPCSLVTGEERRAVDVGLKEDDDHTLSACTVEMVPLNKTIDVAVIDEIQMIGNPERGWAWTQALLGVKAKEVHLCGEARTVPLIKELCASVGDKLEIHRYERLSPLQMAETSLDGDMRKLRKGDCIVSFSVMGIHALRKQIEQSTGRKVATVYGSLPPETRAAQARLFNDPYNDYDFLVASDAVGMGLNLAIKRIIFETSSKFDGTQRRTLAIADIKQIAGRAGRFRTAAQASDTPASEQDLAAAKGEIAAGATFGKKYSDQDAPDNVGLVTTMERFDYPIVSAAMQSEPEPIMSAGLFPPASVLERFASYFPPGTPFSYILTRLHELSQMHKRFHLCGLRDQIWLADLIEPVKGLTVTDRNVICSSPAGKADEEMWRHLIPALARCIALQSGGDLYDIKEMPLEFLELEVSASRDYLRGLERLHKGVVNYLWLSYRMPGIFNTRKLAFHVKGLVEEKIEDVLSKFSFSETSRRKMAAKREKEILESMIVGGAEGAEGDVPSAHPSERYVGAQAETETQDQPVLDIEDEENKAEQKLAELAQNDPDTSKVEQTQELAPAPEEDATSGIAPDLEGQKILTSGGDHFSGEEELPFVEPDLPVSPEVDIKQSAPNVEDRGSGDIQDDNKVIEELTGHEEDVPQKSNEAAAGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC3</accession>
    <name>A0A9Q8PEC3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765223.1">
        <property type="nucleotide sequence ID" value="XM_047910396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC3"/>
    <dbReference type="GeneID" id="71991126"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11248"/>
    <dbReference type="OrthoDB" id="10545667at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="413" mass="47329" checksum="BD0F4D7E82A5FBF3" modified="2023-09-13" version="1">MCWRAGISIFFFPSLLLFYIPNNHDIPVPPAHNDNFHSYFTTAREQIDIMKQGRFNASLLLLASIAAWCAAVPLNGTTSIARRMDPDDMGPEEVVNRMGELHSVGGCWINYMIMPVLPNMNDVRDLAMRHVLPSGWSRNDRTGERLPPPVQEIHKLDGVQGLRQMDTHPTPPVSLHRAGWVWAELDHNRRYLYDGTQEPPAGWSFHGLYNRHQRAIVITRAYGKDINTTPYPLPPTHDQFLQRPPGIYEWSQLTWMEFRKIQMREHCKPIRTAMFPALEGTPEDVYFFRYAGNRLRNSNVPLPPKPGFTFPIGSYGHQLLLGTPLGQQMSRLMYENKHITDPSVIVAIHVWDSGAPGGMMPTVVFSAERYDARIRDMRQANLDAGGDEPMFNDWPHKFLPNFVRRERAPRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEE9</accession>
    <name>A0A9Q8PEE9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765425.1">
        <property type="nucleotide sequence ID" value="XM_047910012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEE9"/>
    <dbReference type="GeneID" id="71990742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10864"/>
    <dbReference type="OMA" id="NTSICDY"/>
    <dbReference type="OrthoDB" id="2110578at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="31916" checksum="E69D9D947E0847BF" modified="2023-09-13" version="1">MKASTVAASLAAATGAVAQRPMDMSICDYYTTALLKENNATNQETLLTLVVNTAVIGNYTMPNVGIKVPGILANGTGEYEGVSLLPYFSGGLVSTNAGGMPKAVNFLDDGGAAPLMMNKPANGTNSAQYRLLTHLYQYFGGLLGCSQFANTTMQYQGETSQYNVHKYMGLNKAEVGYFISQVGMSAASFGVTEDDVKAVGMALNDAFGYRCAAPAAIPATATPALQAICIAEDCPIATANATCAAYDPVMEPAMATGSMMAGGGMSGSNSSMPSGSSSGMASPTGMEPAMSTGGAGSLVAPVIGVAAMGLAVMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFI5</accession>
    <name>A0A9Q8PFI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Granaticin polyketide synthase putative ketoacyl reductase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09368</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71989246"/>
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    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF13">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="499" mass="54233" checksum="AB43D902DB9718ED" modified="2023-09-13" version="1">MAAQKVALITAGTAGLGAQIARVLAPDFRLAINYANNQDRAKALLGELEQIPNTTNSTELPRFETFQADVGDRPSLQKLVEQTVAKFGRLDVVVSNAGWTRITNFANLEEGMIEEDWDKCFLYNVKAHLWLMHAAKPELEKTEGAFITTASIAGVKPSGSSLPYSVTKAAAIHLTKGLAVIAAPKIRVNSVSPGLMLTEWGMKFPKAKIEAATNNTKLKRLATVEDVANSLRGLVLNQSVTGSNCTCISSFLCLHPFCNTYITSFYFFAFKHSSRARSSGAEVQCFDLVALDTGRHLENALGFTSNTVNKRKNAFRVLLPTSFTKFALTPRGHRGTRGIALYNYNATASLSSFNHDQSSTPPNTMYTFTQSLAIATALLSTTNALPKQDTRLQLAERAALVPSTIGLYVCDDANWKGKCEHLLESPGVCYTLPDGLLKKISSVGPDDGMDHGASGCTLFETKNCSGEYLKDIAFPGEGDLSKKPAAGRYNDFFQSYICY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFM8</accession>
    <name>A0A9Q8PFM8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766085.1">
        <property type="nucleotide sequence ID" value="XM_047908213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFM8"/>
    <dbReference type="GeneID" id="71988943"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09065"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="26624" checksum="6F68AB72514C9A35" modified="2023-09-13" version="1">MTCRQIRNEALAIYWSENTFCAIEPLFCLHHMATDSGLCCLLQRHFYQRLPMQRQPMQLQPMQLIPVQLQPMQLQAVQHQPMQQTRPTSPLLTWLQKIGSTKAQLITTLQLSYHFNDPTNPHNYRVLLEDCFVSVSQPAQWHIKNTEKAGLKLGAIELVARTHYLCQDSYGGCKNSSDCILIGDLKEFVKKLVEGKGKKRKTELEKLCGRSRWAYQVPRTIKILATVDSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG87</accession>
    <name>A0A9Q8PG87_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766302.1">
        <property type="nucleotide sequence ID" value="XM_047908839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG87"/>
    <dbReference type="GeneID" id="71989569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09691"/>
    <dbReference type="OMA" id="MCDRFTA"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="33167" checksum="D8BE3D742CAF601A" modified="2023-09-13" version="1">MSEGAAAPSESLFRASKRRKVSRKRIAEDDAPSDALDVTEANPEQRHQDGSEQRSIVRRPAAKKHGISFSNSGAQGERRAESDMQVALVPAVKQDEVDVVQTDRFMKPTGKVVVEDKHLTAYVDSKLAELRSSTSTPTLTDGSHMIGGPADTNVHSSVPTSPASTAAMSAPSHDTIHATSNAQRRAQAHADRIRNKQRRRQPQIDPSAMARDAMVDRIMQESQVPMYDRPAAAATGIDSDEAAAEAFKAEFLASLEDQNRRRPPAPPPAQRGAANSAVPATGPKLGGSRQQREKMKAIEEAKAAAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGK1</accession>
    <name>A0A9Q8PGK1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09674</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766444.1">
        <property type="nucleotide sequence ID" value="XM_047908822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGK1"/>
    <dbReference type="GeneID" id="71989552"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09674"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="35671" checksum="586AC21FD6109881" modified="2023-09-13" version="1">MSSPAPEVGTGVAKKCRLLMLPAELRVFVYEELLEHEGKGAKSLSPQILLACKQINREAQPILDNNLKRLSFIRIHADDDGVTIKHGEAPSTQIDRIKHLSAASDAVPPVPTGHTHAIIHLHLADRTFASQIHTSFLLNQHLYLLVAQLNNSKILSLSLSLSLRSRTKHSSDPEAYDWRTILWPLTRVGPKVTVSHRHSDISQASFQHLSSPRVQDEMPVTTLSTFLKLRRNVEVFSEISMEAGVNSDEARRVVERLCGQRFLPDLDRGLVCYPMTAKQMEELVGERYQETMRVLDGDWFRQAVLDSMVFPGVQQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGN7</accession>
    <name>A0A9Q8PGN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter cpaT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766451.1">
        <property type="nucleotide sequence ID" value="XM_047908577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGN7"/>
    <dbReference type="GeneID" id="71989307"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09429"/>
    <dbReference type="OMA" id="GYGWGFM"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000509">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF163">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="491" mass="53127" checksum="38FF51611E0858DC" modified="2023-09-13" version="1">MAHASDERQPLLHNDTTARTYDDASKDLVDFDPNGDAEDPLQWPNAYKWSIVALLATMAFVVTFTCISLVPVASHIVTELDGTPSKSASVLLVTIWELGEAAGPLFIAPLSEVYGRWPVLNAANALFVAATVMASLAPTSHVLIAARFLTGLAVASNVLNPAIVGDMFISEQRGTAMSLIMLAPLMGGAIGPAISGYIAESLGWRPVLYVSAGLALFLEFLFLACFRETFKVPILKKRAAKLREETGNANLRCAFETGKGQSSHQIWESMLRPFVVLAGSGVLQALSLFGSVVFTYFYIFSTTLPDILQDIYGLSPSQTGFAFISFSAGSIISVTLCNQLLDRIYIRLRDTRKGVGQPEYRLPLVIVGAFFLPFIAAMYGWVAQARVGIVWSLVSVALLGAGIMLGFLPVMAYVVDAFGLYSASALTALIVTRCLMGTFLPLATAPLVDLWGYGWAFTTLGAITMALAPTPVLIMRYGAKWRQKSKYTREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGR6</accession>
    <name>A0A9Q8PGR6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766685.1">
        <property type="nucleotide sequence ID" value="XM_047908342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGR6"/>
    <dbReference type="GeneID" id="71989072"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09194"/>
    <dbReference type="OrthoDB" id="2444174at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043837">
        <property type="entry name" value="Mtf2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040009">
        <property type="entry name" value="Mtf2/C5D6.12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468:SF1">
        <property type="entry name" value="MTF2-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19189">
        <property type="entry name" value="Mtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mtf2-like C-terminal" evidence="2">
        <location>
            <begin position="228"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="450" mass="50284" checksum="BA9D885EFD719BA3" modified="2023-09-13" version="1">MSASLLSRTSRQPLMREGIVLPFLYRTKTILRAYADKSEDTAAYVPTHPKLEQERSTDASSPQRRRQNAEERPGRLRESRSPRSRASGRTRTNADTSARSRDDGDAPGRRQASTRDRERLPDVPFEGHIPSNDPNVRVQGTTITPKELAIFETLFRSKQVKPADSKKAGAQQQKAANMAKVVPNFPAPLRALADEARVLHANATSEDQDAGDISSRSLRTSEAAEKFFARIKARMDKASTDVALWQIMTDEVFNNIKALKLDDPCARASMKPEDVEGLTRSLPSILLHFMSLMQSKLPGSSYGLVLLPTLKKLGPSAFALGATTDLYNEHMQIIYKQYSDLDSIASTMAEMDKEVYEFNSGTSKLLQSIFQRERAATSGRMGPGMQALWTTDRKTRALEKLRRWDKTVQEQLRAAAVRKAREKEFQSEADAEDERELEAYGGSHTYVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGY8</accession>
    <name>A0A9Q8PGY8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Citrate exporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09509</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766568.1">
        <property type="nucleotide sequence ID" value="XM_047908657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGY8"/>
    <dbReference type="GeneID" id="71989387"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09509"/>
    <dbReference type="OMA" id="CWTIAMA"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="650" mass="70308" checksum="7FD5A46F7971498C" modified="2023-09-13" version="1">MTGIESSTRLLNMSYQYGGTSMRMPPHVSMQADRLPQRPPRKSWSRLKAIVAPAKSPPNHALLTGWDLGLAVVALNFVNGVAFVDILGIGVIQSAVSDHYNGHDAVDWNTTSALIGAAVGQCILGYMSDVFTRRKMLLFAVALLFLGALGCASSASTSHAELLVLCRAICGVAVGSISNLVNISQNDICTEEQRLNLQGVQGTSVALGSIIGSLAAALLPHWRQLYFLEAALALVAIFAIYKFLPPNRDMPARSEIRKEVGRIDYLGILTGMGWLIPGLILLSKWRKFDTPVLVALSVVATLSAVLFGMLGSRTELADDQPKPPGLLRKLTCRRSRAIAPFRLFKNRTVAAIYAQNVLFGAAFYSFVYFVPVQAQVVRQEPALTGVYKLIPYFVTHAVWSTVSARVIKVFQSKGWVSYSVVMGFGFCCWTIAMALLGWDCTQPDFSHFYGFAVLVGFGTGSVFQNSVLAITKQVMSDDKAVALGTRNVLRFVGGAIGTGLSSMTMRTVVRHELPDRLDHVADSAVADHSYIKNLPEVDRALVRAANARGIAIVWYTFAGVLGLCAILCVLIKDRVAKKEEDEEKILRPGSSDSPIQPAPLDDEKSRPGSGNASMLSTPLPAYLGRNGSEDSVQRAHPAAPSVHSTPLGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH91</accession>
    <name>A0A9Q8PH91_PASFU</name>
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            <fullName evidence="4">Transmembrane protein UsgS</fullName>
        </recommendedName>
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO22381.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41949" checksum="0E9AB327615EDE4B" modified="2023-09-13" version="1">MSNYGSFGSFELNSIVRGAQLTLVGANRALQNPGLFSSEHYKQAALAVAAGIAIRLLVAIPTLGIRVLLRSLGLFTDLSGSTWDEDIVQGIEFIEHSVLQVPFFLMSFMRYLSPAMDQMFMNSLQWVDQTYLQKHKSEDPSGLRAMYYPNLRLYSEHAKTAQKKEPKEAMTAFFMRFGKKAVLSLGIYLLSFIPYVGRFVLPAASFYTFNKAVGLQPAVLIFGSSLFLPKRYLVMFLQSYFSSRSLMRELLEPYFSRIRYTSEQKRKWFHDREGVLYGFALAFFVFLKIPLLGVLIYGVAEASTAYLITKITEPPPAPAEAEEFKKMDVKWENKHEFLSLPLDALDKFNTTAKGKQVRPDTTGNLGKQFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF579">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="7"/>
            <end position="202"/>
        </location>
    </feature>
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        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="37015" checksum="30E16B4B1FF504E3" modified="2023-09-13" version="1">MEGIDTVLVTRATGFIGAHIVDGLLKKGVTVRGTTRSLAKAEQMKAARPEHALKLHFVQMRDFSGDVNFSEAVAGVDAIVHTASPLTYDTTDNEKELILPAINGVKAILSAAANTGKVKRVVLTSSFASVIDIGRNAGPGFTYTAQHWNPLTYEEAIAPETNAVVAYRGSKKFAELEAWNFVEREKPSFDLVAFCPPMTFGPIAHPVLEPSQLNESNARLWDVAVGQPLPEARVPVWIDVRDLAAMHVEAVFSDKAGGKRYVPASPGKYLYELAASVLRSHFPAAIGQVVEIDEASPPVGYYLDGKAVTEDLGIQYRDFETTVVDLFGSLEALEIYPWKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI10</accession>
    <name>A0A9Q8PI10_PASFU</name>
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        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI10"/>
    <dbReference type="GeneID" id="71992051"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12173"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="36768" checksum="E93D4EDC408F8726" modified="2023-09-13" version="1">MALPAQADFLANLAADKCPICYEPFVVPIKTECGHSFCMKCAKEWFTTARTCPSCRTPLYKKPEDWEDSDSDEGEDIESSEEIVDEEIQVAPRTLTVIPDTDGPLIYDDWIHVELLDAEENLEVNLDDDLFRETLVSLCFTEEDHKHFWEARPDWDDPILITRLHLRSQTIAAIVRLTPDFESAIEARLNFREACCWSGWAEAGRYVLAKLSELWDEWPEQTARALYGDLSSGWLQHLEVVGLPLPKYDERCETWGTFEQNVDQLFTQVVIFAQETARRYSNARNRSSLPTVDCRGHDREEEFEHQEEEGGLVRCRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI77</accession>
    <name>A0A9Q8PI77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767352.1">
        <property type="nucleotide sequence ID" value="XM_047911023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI77"/>
    <dbReference type="GeneID" id="71991753"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11875"/>
    <dbReference type="OMA" id="KYSEDNW"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="34839" checksum="C3B9D5746C29FE6D" modified="2023-09-13" version="1">MAPSRISPAPSTDLHGLTPEQLQTWDDKGYLLIPDALSQSQVKNLLAESQRMLSEFSLADHPMTRFSTGETSSHVGDDYFLTSGDKIRFFFEEDAFDKQGSLTKSKEKAINKIGHYLHQLNPSFKDASINEKNARIARDLGFKDPRVLQSMVICKQPEIGGRVPPHQDSVFLYTDPPSAVGFWYALEDCTVENGCLSFAAGSHKRAPILDRFVRSDDGKGTTFAKNEGSAWPKSSNQEQGIEDEQYELGEVKAGTLVLIHGNLLHKSERNTSLKGRMIYTFHMIEGGHRYDERNWLQPPSEGFTALNEAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI98</accession>
    <name>A0A9Q8PI98_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767346.1">
        <property type="nucleotide sequence ID" value="XM_047911573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI98"/>
    <dbReference type="GeneID" id="71992303"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12425"/>
    <dbReference type="OrthoDB" id="3816801at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="105" mass="11801" checksum="9DF651489997BFE9" modified="2023-09-13" version="1">MKQAHYEQANVRGFPPKPKGELVVLRGSNEGIYLENRKLEGALVPSSSRRAAALPERNSRLDQSYDNEDGDDDDESNDDGDNDDDEPGEDEENSDTRTSRLWNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PID8</accession>
    <name>A0A9Q8PID8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767353.1">
        <property type="nucleotide sequence ID" value="XM_047911022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PID8"/>
    <dbReference type="GeneID" id="71991752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11874"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="83" mass="9489" checksum="1279A1CDB32CD542" modified="2023-09-13" version="1">MAMRLLTTHLLPRPVRVGTMMPFDPTELRVWSRNKNGKPQKKVPTRRSDPVMIYSEICSRAPTLTSQHAILQGVLPWLPNVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIG2</accession>
    <name>A0A9Q8PIG2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sterol 3-beta-glucosyltransferase UGT80A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767487.1">
        <property type="nucleotide sequence ID" value="XM_047911233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991963"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12085"/>
    <dbReference type="OMA" id="SFAHIHV"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000100">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="154"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="488"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="748"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="769"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="794"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1066"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1153"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1231"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1309" mass="142540" checksum="147D7745389747CD" modified="2023-09-13" version="1">MAPSDEPAQKGGREERELGQVPNEMLRQAAAAVAGENDATASERRHTGQDVPLEVAEGLDTTQTEHDVPPPAYGEDYGTVSQEQEGFGTKASVAEDGRVNIRIDQRNRRLSQLLVPSLAQLQRAADEEHAPPPPYIPPSLGGEEGIAPPPPMNVVIQVVGSRGDVQPFVALGKILKDRYGHRVRLATHPNFKDFITENGLEFFSIGGDPQALMAFMVKNPGLMPGFDTMRSGDVGMRRKEIGEYLKGCWRSCFETGEGLGIEATDQTIEDWTRQHADEDDYLHRPFVADCIIANPPSFAHVHIAEKMGIPLHVMFTMPYSPTQAFPHPLANIQSSNADTHLTNYISYALVDMLTWQGLGDVINRFRQRSLGLDAISLMWAPGMLQRLRIPHTYCWSPALIPKPKDWGANISISGFFFLDLASNYEPDPELKAFLDAGPPPVYIGFGSIVLDDPNGMTKMIFEAVEKIGQRALVSKGWGGVGADELGKPDNVFMLGNCPHDWLFKRVSCVVHHGGAGTTAAGITAGRPTLVVPFFGDQPFWGAMVARAGAGPEPIPHKQLTADNLAEGIQKCLEPQSQERAHELADKIARENGSELGAQSFHQFLDVDKLRCNLAPSRPAVWRIKRTQARLSVLAACTLAQEGLLDFNDLKLFRPREYETDEGPWDPITGGATALIGTMSTMMLGVADFPIETLKALNIHPDSKANKAKAQAAKEAEGKGKQPERSDSPGNSTRSGLEGRPSGDTAVHGSPSPSGTSTPRSGGDSALFSEPTSQPSSRSGSTFNVNESLAKLNTGSLSPGSGSRSSSMADALSGSLGGGNRPRSRSNSRKPSPKGSSSSNAGGMMQTATNTGKGVNRIIGAGLKSPMDFTMNLSKGFRNAPKLYGDTTVRPAEKVTDLKSGLRAATKEFGFGMYDGITGLVSQPVKGAAKEGAAGFFKGIGKGIGGIALKPGAAFFAIPGYTMKGIYKEVQKQFGSSVQNYIMAARTAQGFDEYHRASIEEKQDIIMRWKVLQKNLKKKRNPDELVRDILDEQMKKKEAWLESRRCGQDDKQTGRSRANSRTSAKSRGTDDPYQHDPENDMLAMGTSQSSSAAQEDQYRIAEERALEEAIRQSVAATSRGDSKEDARVAEGMRANMAEVQRTRTARAADDDDEDMRRAMAESAAEAERNQHESQRHDTELERALAQSLREQRGWQDSDDEQMVQSPISEATIPADEPPAYDPGHLAGTTQEEYERNHSEKPGRSEKTSAEQEEERIVMEYIKKQSVLEEENRKKAKAPQIQVNDEDDEELQRALKISMQGHGQHGEASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIY1</accession>
    <name>A0A9Q8PIY1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SWR1 complex subunit vps71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767664.1">
        <property type="nucleotide sequence ID" value="XM_047912272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIY1"/>
    <dbReference type="GeneID" id="71993002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13124"/>
    <dbReference type="OMA" id="CCMCGYW"/>
    <dbReference type="OrthoDB" id="74807at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="31192" checksum="8A8CB7BEFC5201D7" modified="2023-09-13" version="1">MATGALRFRTPHIEELPIATNRQAPGFTYVAVSGPVVDPSKDWGTTNRKRSRTTGLNQSESQKEALSARQQREVERKIKDLNSDSAKDVQIPIPKKSQSTGGLHRAGKTPGTKKILASGKTFAHYLDDEEAEIARTGRRDGDVEPQATATHRASKTPLARRKPQREESSMSGSPAPSGPAPPALLQQQSTSALTETFLMDVETDETDSSIPPLPSQAEMDALLNAPPLTYNQARSAPPPASAPPPRKFCEICGYWGRVKCMKCGNMTCSVHCKDTHDEHKCLKFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ24</accession>
    <name>A0A9Q8PJ24_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small nuclear ribonucleoprotein Sm D1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">snRNP core protein D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_13091</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in splicing regulation. Facilitates post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the snRNP core protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767754.1">
        <property type="nucleotide sequence ID" value="XM_047912239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ24"/>
    <dbReference type="GeneID" id="71992969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13091"/>
    <dbReference type="OMA" id="TFLMKLT"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097525">
        <property type="term" value="C:spliceosomal snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01724">
        <property type="entry name" value="Sm_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000008">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034102">
        <property type="entry name" value="Sm_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7 10" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14006" checksum="BF88A38A2FEE485A" modified="2023-09-13" version="1">MKLVRFLMKCTNETVTIELKTGTIVQGTIASVSPQMNTNLRNAKMTPKGGSQISLDHISIRGSEIRYYILPDSLPLDTLLIDDTPKPKNKARKEQDKSAAAGGPGGMRGGRGGPRGGGRGRGRGRGRGRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ57</accession>
    <name>A0A9Q8PJ57_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Urea transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13282</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767794.1">
        <property type="nucleotide sequence ID" value="XM_047912430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ57"/>
    <dbReference type="GeneID" id="71993160"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13282"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="362"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="41777" checksum="8A56E5C7A576D0E7" modified="2023-09-13" version="1">MVAELSALQQVVNLLTGLNGLPAVIVQCFITTIYTAAGGFRVSFVTDNVQGAMVLLFLIIGTVTIAVTVNIDTSLIPVSNYLEPSLLGWQLIYVLPVAILTNDFFLSGFWMRAFASKTDKDLWIGVCISAVVVTIVATLVGVSGLIAGWSGVLGVPPVASGMELFTLLGTLPAWVVGIILVMVVTLSTAAFDSLQSALISTGSNDFFRNKLNIWIVRLIVVILIVPTVVVALKSPSVLQIYLISDIISASIIPCLVIGLSSKAYFWRGFEVVVGGLGGILSVFFFGLVYYDGNASRAGNLLILTEGLYASDWSVFGAFVAAPVGGLLFAIAGCASRLGFEWAMAKVRGTRFTALDRDEAPAAAFEPEERYSVDDAASAGPSHGRKSGVMFTKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJG8</accession>
    <name>A0A9Q8PJG8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJG8"/>
    <dbReference type="GeneID" id="71993086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13208"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="616" mass="69125" checksum="51B76EB677FCEF1F" modified="2023-09-13" version="1">MSVSSEIHVGVAQCLDAIKQAFNDGGAIIEKIKRKRALKRAPPPPRLLEESIDQAPHEIEKEKQRGLNRFGKAFDDGDAIAVITLQQICIKLQSSLLEKLRNAAFDDDHAITDFTYLVDAADIGRDKTIAALHDFKQRLLSAQTPEQDADPGQVVKQQSLKSMSPNSSKSDIVTPPSEPARRDTIQSLPPEPVRSQTHQSLPSQSQTKTLAPARHHKTWSRDFSHSAEGSGEDTTSGADEPTHQAHHRKRSSILHFLKHNRTHSSEVKDNRQGSVLPAVITEEPVRQPSLSGPTSTPSQQAPQQRVSQEQVPQQQSAKFRYEEWEDNPEEIWGTKPSLERRETVALAPDQARDNASVYNGHGAQSLGPSLSPVLTHRSNSNPHHSTAIITPNPDNEFLGFCKGAWKLQNGDRKGAMTKKSEVDPWSRHPSANAAQYLSCLQPKCAFRSSFANANVEVMWNKVFIFEAKGIKLRWPFLAKSHVQQKVVVKHQYSFKCLFCVFLGGQSGVYHGMDYYLEHILNEHRGRALGDVVLYKTGCINDRIADDKDEFDINLYPMALDNPKEKAKSEYLSDDLMDPYWAKSEANDSMFSPNEPWNEGLSDFHYRMDDRYGAELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKZ6</accession>
    <name>A0A9Q8PKZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13918</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768754.1">
        <property type="nucleotide sequence ID" value="XM_047913066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKZ6"/>
    <dbReference type="GeneID" id="71993796"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13918"/>
    <dbReference type="OMA" id="FRIAPWH"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF18">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE APDE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="513" mass="58202" checksum="CAA72B059C8C851E" modified="2023-09-13" version="1">MAWLLSPTNLAAIALLTVICYKIWAVRNAEREVQRLEKEFGCAPPPLWAARWPMGIDLLLKALWSQFRHGKVMEFFLKVSNLSGPTHIQSFLGMRNIGTTSPKNLEAILKEQAKEFNLGFRIPQFRDLMGDGVFTQDGVEWQHSRDLLRPIFKSTRYQGFEDIRQSVESMLDKIDPTTVVDMQPLFFSLTFETTLFMLFGASAYRMISRQEGEQGAEFQNSFNTAQEYLSYRTRVGDLWWLFNGPGMWRACSTVHRFLDSAIKEALEAKYERDSEPDNARKYVFIDALIEQTKDPKVLRDQCLSLLLAGRDSTAACLVWTLRLLARHEGVLEKVRDEVVSAVGLGHDAPQPSREDLSNMPYLELVIKESLRLYPPVPVNQRAASKTTTLPEGGGPDGKSKVLVEKGASVGYLTYALHRREDLYGKDALEFKPERWQDEALKNIGCGYLPFGVGRRSCLGREFAMLEATYTVARMVQRFPFVRVAEGQTLKIGEERQLLTLALSSGEGCFLRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL39</accession>
    <name>A0A9Q8PL39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UPF0591 membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768846.1">
        <property type="nucleotide sequence ID" value="XM_047912952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL39"/>
    <dbReference type="GeneID" id="71993682"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13804"/>
    <dbReference type="OrthoDB" id="2344991at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638:SF1">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="207" mass="22135" checksum="F8DF7786DD07FB4D" modified="2023-09-13" version="1">MALCWKVQLASKHLLPFSSPRPHLINNLPKSTLELLSHHLNQLQSTSNIPKMATLHYLPPVKPSAIALGTVFNHAASLAILGPVFGDTYRRAQQANSSEEFFKSKEAASAASAWGTSLVGSAVQSYGVGALINATGTLSYKGAAYLGALIFAASSAPSFIAQIFTEKRPLDTVAVGATARIFETVGLSLFLTWWGTRTSPFEAARFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR10</accession>
    <name>A0A9Q8UR10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,2-beta-oligomannan phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763592.1">
        <property type="nucleotide sequence ID" value="XM_047906063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR10"/>
    <dbReference type="GeneID" id="71986793"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06915"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18610">
        <property type="entry name" value="GH130_BT3780-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106:SF5">
        <property type="entry name" value="GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="406" mass="44737" checksum="32F39C1DA246FC27" modified="2023-09-13" version="1">MYQSSLELLVNAHAPAMMFQQLLSTNLLCFSAAVAQEVSSADQLPFPISKDTIEGDPNYIAPVYPILPFNQYANNPILSPNPANDWESAFLYNPTTIVLNETIFLLYRAQNASKTSSVGLAWSTDGYSFTRLNQPVLYATEPWEAGGGTEDPRITRVNGTFYLTYTGYNLTSPQLCLATSTDLLTWAKYPPLFPNWQDVAYSDIDIPEPRFNHSKSAAITNEKSTDGLYHMYWGDSFFYHATSPDMLNWTTLPASQYFAAPLLSWENRLIEPGPAPIKTRDGRWILVYNGATSGRVGYPPAQYGVGQMLIDPSGAFRPTVNTSIVSPVTGGTYQPAIADGPVARIERPMVFPSTPEETEGQVNRVTFAEGLVQSKGKWFLYFGQADSTLGVATAEVQPCDLDCGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USF2</accession>
    <name>A0A9Q8USF2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765104.1">
        <property type="nucleotide sequence ID" value="XM_047910290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USF2"/>
    <dbReference type="GeneID" id="71991020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11142"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="21181" checksum="A1B78DF341AF1D8E" modified="2023-09-13" version="1">MAPASNSTMHKVLNTTELLESILLHADTKTLLACLQVSKRLNKVIRKSPALLQHNFLAPITKASELSAQSSVTNEFVIERKILVCAQRCCWFKIHRAHNHVGKKTDSEYGVTFFHSYCSEQSRARQSWQVMLLEQPPRKIRIKHICRTCFGKQNHNIVMSAEDRLRDLGIKLFAEHGSIVHSYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USP9</accession>
    <name>A0A9Q8USP9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="5">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_11400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="5"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765392.1">
        <property type="nucleotide sequence ID" value="XM_047910548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USP9"/>
    <dbReference type="GeneID" id="71991278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11400"/>
    <dbReference type="OMA" id="REAYWER"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="530"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO21026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="62027" checksum="9FEB4A38FBDB1E20" modified="2023-09-13" version="1">MSVPSNVPDYDVIVVGGGFSGCCLLKLLREQGFSVLLLEANSRLGGVWAWTHYPGARVDSELPYYGYSDPAIWSTWTWTERFSSNQELRGYFDHVDQVWDLSRDVSYNTKVTGAQWSDESATWLISTGEGQPQYRCTWFVSAIGTSSKPYVPNIRNLESFQGTMVHSSDWPETGIDIAGKRVAIIGAGSTGVQIMQESAKIASRVVQYSKTPNYALPMRQRPIHEEEIYTTKAHIPYLFQACRTTRIGLPVSNTGKKTFDVSDEERQAIWEDTWKRGGFNWSQGGFIDTVFDTKANRAAYDFWCKKTRARIIDPVKADILAPREPPYWILTKRPSLEQDYFEMCDRPNVELTNTPILEFSESGIVTEDGQVREFDVVALCTGYDAVTGGLRAMNIKGRDGLDLDEKWKDGIQTHLGMVVNGFPNMFMAYGPQAPTSLTNGPPFIEIQSEWIVQTLCRQREEKIVALEPKLEKEEAWRQTVAKLANSTLLSKTKSWYTGSNVPGKRNEFLLYIGGIPQWKEECDRALEGWDGFDNKQRKDSHQSGVKVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTP2</accession>
    <name>A0A9Q8UTP2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766442.1">
        <property type="nucleotide sequence ID" value="XM_047908824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTP2"/>
    <dbReference type="GeneID" id="71989554"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09676"/>
    <dbReference type="OMA" id="VSDHRLK"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="190"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="34379" checksum="215390BF66BAC10C" modified="2023-09-13" version="1">MPTKAPPAAKPSKNIFDPFNSSATGHQRADNRLSGSTSWRDSRSLKLRQQFSAGAGGGKRVSDTVGAGSLDFGLDGRTENGGWVRGAKGLRTGGQQSLWETVKVTKDEEDEDRPAKRVKVEAERDRPNTVVSPFTPFRKADGTVRETSWTSHECSPSDLLEPIDPAAATPDTITKSEPTKDEEKGDEPPKPPQVFAYCNFYINGSTAPYSDHKIKHIFSTHGGNTSISLGRRTVTHVVIGKPSKEGGACGGGLASSKIQKEITSKCGNSVKFVNVEWVMDSVKMGKRQPESKYEGMKLAPKGVKGINTMFKPKEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU68</accession>
    <name>A0A9Q8UU68_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA ligase D 3'-phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766951.1">
        <property type="nucleotide sequence ID" value="XM_047911007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU68"/>
    <dbReference type="GeneID" id="71991737"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11859"/>
    <dbReference type="OMA" id="SIHQRKW"/>
    <dbReference type="OrthoDB" id="2588098at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465:SF1">
        <property type="entry name" value="DNA LIGASE D 3'-PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465">
        <property type="entry name" value="DNA LIGASE D, 3'-PHOSPHOESTERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA ligase D 3'-phosphoesterase" evidence="2">
        <location>
            <begin position="111"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="412" mass="46080" checksum="DD6270C68A179F17" modified="2023-09-13" version="1">MARSGTLHRDISPPPLRKASTVAKNAGKPEQPKKELEEHNDETHEKCAPGGKSDLAAIEAGEVEIRDHLEYFFHHLSSASRPAVGPRISFDAWRDLYKRSQHPHGRHFVVHQHDHPVSGVHYDLRLQISATSSISFAVPYGLPGNPNSQRPNRMAIETRVHNLWNHLIESASHATGSLLIWDTGQYEVLPRPRKRQKTTDDELSNDEASTKLDNLSQSELLHQAFQSRHIHLRLNGARLPLGYTIALRLPASNHTAAQPKKPARKWRRQHPSKAARKTSVVTDSDYDSGTVPSSPVAIDAEAEEEDLAAAIASEDDEDATIRANNAYTGATNSIGSVHQRHWFLTLDRTYSGFRKAGNGPDAGQWVGDWEAFYVRGRDVERSVVTGRNADEVMADENVEEFVGRKMWRPITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVA2</accession>
    <name>A0A9Q8UVA2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_12920</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768150.1">
        <property type="nucleotide sequence ID" value="XM_047912068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVA2"/>
    <dbReference type="GeneID" id="71992798"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12920"/>
    <dbReference type="OMA" id="HILHFAC"/>
    <dbReference type="OrthoDB" id="7759664at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="350"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="603"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="661"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="661"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="689"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="735"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="780"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="828"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO23784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="838" mass="91536" checksum="55A97098B5D6760E" modified="2023-09-13" version="1">MRLAYYAGASTAAAAACLLKAFHQRPNFYSATVYLSQSNACLLILTNLLLVLACSFMFALQRLLYGPLRPIEIEQLSEKAWYAVLDTLLAMPSFREDVGGWLLTMFVLLLAGKVWGWIAEGRVDIFEQQPPANPTLFHVRLAMSLLVSFIFDVLMLWYCLETIIANPKPGMMVIFTFEFAILGIFSLFTGLRYLLACYEAKEVKKQTMLAIETRKVEIREERVAAHAAAVAAAAQNTAEDGTPATVPPMDDSPIDVDENEVDVPGWEEKRRYLFVLEVVTDFMKLMIYIVFFTVSITFNGLPMHIMRDVYMTFASFSKRVSDYVAYRKATSDMNTRYPDATTEEIRGDPCIVCRDTMVSWEQPPAAANAQPAGDQPVAAPAPARRRDEGLRAKKLPCGHILHLRCLKSWLERQQVCPTCRRPVVTATAPNAPAAPGNPPAPGQPGQQQAPRPRARIFNLGPLRIGLLNAPQGQIQDFINRFQNPDAANQNAAGANQQGPNHLGLQVPYANGQAQIPTGTRRTGRRSQVPIDVGIMQMEQRIMQEAHNLNIEQQQLATLRMMEGEMARLRAQHTPTQQPVGAGGAARQAAIVQQMGRFPMPGFMPTQQPFMPPTQPEALQGSPAQQMGPGHENLPQGLILPEGWTLMPLHRVDQEHHAAPLQATTRNLDNPTADDGSTSARPISGDDDTATSAATETPSSATQQQQQPQPPQQVAQSAGPVDDTGSPLFVPTAPRTSDTTSTEATTASSDQTQFQPAPQMMTPQTPAASSSSTQDPTQTPWSGSNWGFDQQPSQASTAEPSSTPDSQVAEQPSGQEGYSGKGKARAVEMEEVPDPEAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVX8</accession>
    <name>A0A9Q8UVX8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13556</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768825.1">
        <property type="nucleotide sequence ID" value="XM_047912704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVX8"/>
    <dbReference type="GeneID" id="71993434"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13556"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56907" checksum="A7A51A990CC58145" modified="2023-09-13" version="1">MATIAGVAGVQFQKGSQFWENDKYQYASSAHGMDHDMNPALIVQATNKEDIKATLSASDMKVLQASKQEDVDLVERATGQLLTKDDRRDFVFTSVSHSLMEFNTFLGKNKLFVPHGQCSHVHLGGHVHTGGYGQLGRSFGLFGDHVWAFWTINADSQEVFVTKGSDPELFWATLGGSPGNFGVTTHVLLEVHRDAHYKGSLGLKAMHLYNKKSVARLVGMVAEMSDNPDFPRNYDLCVSVLSGSFPLCALWPGLDSEIKEEQPSIFGEDNMLGWPRIIVVYAQWVPFSPTDKPDMTWFSRLQDGAIRLYQEGTLQKPMSELTPMWLFRDVREFDLPYVKRTYLTKSTPLQKDNWVPWITSRIDEIVAPLDNYLCFSCQIQAFGGKNSMFTRNADNGTSYSWRDSTMCCTIDAFHCSGHKQAAEDWQAENDQVGVGPGGIFSRQDRRVLWGSYGRREGEDGFDLDSVWERYYDDRGKYERLMRARAKANPYGTFTPNSFCVKRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWM6</accession>
    <name>A0A9Q8UWM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769428.1">
        <property type="nucleotide sequence ID" value="XM_047913480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWM6"/>
    <dbReference type="GeneID" id="71994210"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14332"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="65" mass="7227" checksum="95DAF4FFDF684CF7" modified="2023-09-13" version="1">MHSRISEPEPRSPLRTQIYVTTPPSAAPIEAMLHINEACVGSERTVRGIKTVPAPKPHDIDRNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="1999-05-01" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>O94223</accession>
    <name>O94223_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrophobin 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hcf-3</name>
        <name evidence="3" type="ORF">CLAFUR5_11054</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="1999-03" db="EMBL/GenBank/DDBJ databases">
            <title>Isolation and characterisation of five different hydrophobin genes of the fungal tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Segers G.C."/>
                <person name="Hamada W."/>
                <person name="Oliver R.P."/>
                <person name="Spanu P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race 4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AJ133701">
        <property type="protein sequence ID" value="CAB39310.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="O94223"/>
    <dbReference type="OMA" id="LNINAQC"/>
    <dbReference type="OrthoDB" id="3648449at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040663637" evidence="1">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CAB39310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="10105" checksum="F8FA293A8BB77CD8" modified="1999-05-01" version="1">MQFIASILAVAAVAYAVAIPDDNSATGASKGSTCATGAQVACCTTNSSNSDLLGNVVGGSCLLDNLSLLSSLNSNCPAGNTFCCPSNSDGTLNINAQCIPISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXI3</accession>
    <name>A0A1P8YXI3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative effector 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CE10</name>
        <name evidence="3" type="ORF">CLAFUR5_13363</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943042">
        <property type="protein sequence ID" value="AQA29213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXI3"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573418" evidence="1">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12547" checksum="A7B6E06701CA641E" modified="2017-04-12" version="1">MRFQSQFFLAALTSTTYAFNDLWACDLFNGATALDCDDNCQSHNIPSATKSCCQKMISKYNGKGNEFGPLQVSIETGGDYVNCYMSYLTNGLTFIAEDFTNCVNDLNYFSCEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6V7</accession>
    <name>A0A9Q8L6V7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH-dependent flavin oxidoreductase nadA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01046</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755669.1">
        <property type="nucleotide sequence ID" value="XM_047900194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6V7"/>
    <dbReference type="GeneID" id="71980924"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01046"/>
    <dbReference type="OMA" id="RMPLMVT"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04733">
        <property type="entry name" value="OYE_like_2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF5">
        <property type="entry name" value="NADH:FLAVIN OXIDOREDUCTASE_NADH OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="19"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="49428" checksum="FB3B2DFABEEAFEAB" modified="2023-09-13" version="1">MAPSPRFESDQVDGSPLGQPLKFEFSGKTAPNRFLKGAMTERISSWDPKNLEARGIPSDKLVHAYKIWGEGQIGLILSGNIMFEYDHLEAAGNPIIPRGAPYEGERFEQFKKMAQGAKAHGDLVVGQVSHPGRQVAENIQKYPVSASDVQLKGNVMGMTFAKPRAATEEDIKNFIEGWAHAAEYLEEAGYDGIQLHGAHGYLLAQFLSPTTNQRTDKYGGSLENRARLILEIAQEVRRRTKPDFIVGIKLNSVEFQDKGFNPEEAKQLCVLLEQNKFDFVELSGGTYEKLAFAHQRESTKKRESFFLEFAELIAPAINKTKTYITGGFKTVGAMVNALQTVDGVGLARPVCQEPHLCKDILEGKVKGAIKQEVDVDNFGLTNVIAGTQIKQIGKNQEPIDMSQDSNVGAFMKDMGEWSEMLAKDSEMNNYGYIDLTSATPVPYGAPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7T6</accession>
    <name>A0A9Q8L7T6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756753.1">
        <property type="nucleotide sequence ID" value="XM_047899451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7T6"/>
    <dbReference type="GeneID" id="71980181"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00303"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF274">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="25206" checksum="50F5548884754D92" modified="2023-09-13" version="1">MARIFITGSSDGIGQAAAKPLTEQGHKVWLHARSQSRAKEAKAAVPNVEGVIIGDLTSIEDTKHLASEANKNGPWDSIVHNAGLGPSNSLGNTGDGLPSTFQVNSLAPYILTALMDKPKRLLYLSSGLHSGGTYSDSKLHDIILANAVARRWTDVQSCALDPGWIQTKMGGSGAPGVVSTPAKAIAEFAAGESGVFGNRTGAYGDPYGVKKPHQAAVREEMQEELLGICERFSGVGFPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Z3</accession>
    <name>A0A9Q8L9Z3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757900.1">
        <property type="nucleotide sequence ID" value="XM_047901567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Z3"/>
    <dbReference type="GeneID" id="71982297"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02419"/>
    <dbReference type="OrthoDB" id="3646551at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="39666" checksum="38FB5104BF8060F9" modified="2023-09-13" version="1">MSHDRREPKRARQACLNCRRKKARCSGKKPVCAFCARLKQNCEWDSPSAESTARPSISRSGSSGRDAVGLAARVALLEAKLSLLSAREIISYNKRPAVTGNEPSHARTSARKRPLPQEVGPDSSSYDGDYASAPSQDVFHHLIDVYLEYFHNQPYTYFHEATFRQKYDEGRLPEYLVLAFAAMAVRFSNHEMYRGRQQEALTAYANASWQQIFEDSFSYGGHLEYPMVPATAALLAVVDFTTGHTKFAWVKFSLTIRFAQGLRLNEEPDEDLPGIEQEERRRTYWSVYLLDTLISIGPSRPPSISNPDCPVQLPCQEDLFCNGPASETEPTLGAVIDDPTAPCHQDLDYFDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA77</accession>
    <name>A0A9Q8LA77_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758020.1">
        <property type="nucleotide sequence ID" value="XM_047902263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA77"/>
    <dbReference type="GeneID" id="71982993"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03115"/>
    <dbReference type="OMA" id="RSMIDHA"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000015">
        <property type="entry name" value="Proteasome subunit alpha type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="26804" checksum="FD07046855E4B465" modified="2023-09-13" version="1">MFIARSEYDRGINTFSPEGRLFQVEYSLEAIKLGSTAIGISTSAGVILGVEKRITSSLLETSSVEKIVEIDRHIGCAMSGLQADARSMIEHARVTSQSHEFHYNERLGVESCTQAICDLALRFGEGADGEESIMSRPFGVALLIAGYDEDGPSLYHAEPSGTFYRYDAKAIGSGSEGAQAELQNEFHKSLTMEEAEVMVLKTLKQVMEEKLDSKNVQLASVTKDKGFRIYTDEEMAGVVGRLEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA91</accession>
    <name>A0A9Q8LA91_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758027.1">
        <property type="nucleotide sequence ID" value="XM_047902260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA91"/>
    <dbReference type="GeneID" id="71982990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03112"/>
    <dbReference type="OMA" id="IALHEHM"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="48213" checksum="27BCB5DE3BF7EA70" modified="2023-09-13" version="1">MGDKKKPKQIDFIVSTGNPNDKSQAANKKRVRSVAALKSWPERRKKMFEQLETSGSGQGAFLVEPEPKRKATSTPKQSQPEPIAAGPLTARSQSPAVAPGPALLPATPPPTEPTYIGLGAGSSIALYHAALAKVPATKAGVSQVHAVHPDTPCQCPQCRMKRRVANTSLGSVTSTQYIIPKRTKRMADGTEKSMPRTGDLARITPPSSPESSPSKGRMDPFHCYPVAYQPWFGHILHHMMTVYAPRGWPALKISDEQGVKWEWFMTQNALSEPALFYVRLLFGSGDMIRLGTVRSEIMYWLRAQAIKCINEALTDEKRCCSDAIILAVGRIALHEHMYGDKYASACVHRPAQKRMIEMRGGMKGLDFPALVKRLMRWSDRIMAVGSGTERLLEDDEANANFSLRESVGAIERWAPHEMPGVRSKIKISDLVNDEDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAB1</accession>
    <name>A0A9Q8LAB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758058.1">
        <property type="nucleotide sequence ID" value="XM_047902735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAB1"/>
    <dbReference type="GeneID" id="71983465"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03587"/>
    <dbReference type="OrthoDB" id="4820608at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040329714" evidence="1">
        <location>
            <begin position="18"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="36160" checksum="619B3C26AB8F964D" modified="2023-09-13" version="1">MLSIEVSLLLLTGVAVAQLPIVTQFPVTTQTSFPAPPCTQGPSSTEQFTVNYNVDDTPFKACLGHSFYNPCIYANPFRLSMSISEGVATFNLTIKNRPSSHLRTYNFESVERGFPLTGLTPIGEYNLLNFANINFVDTDPDFDGNHLGLAPHTYPYAATFGAGTSSLTGQTPLISIDYIESTLSSFTPRSFWYGCVLPSPYTAGSLPVSCNITATGYSQAGEQLASQTFAFMTNGSVIQDQNFGTFKGFNNIYSLGFSVSNPVAAAALIDNLIATLEQQSAGRTILVVTTMARSRKTRLDIFVTRFLWQLHMQMIVLRQRIAQHCIDCRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBA6</accession>
    <name>A0A9Q8LBA6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02587</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758605.1">
        <property type="nucleotide sequence ID" value="XM_047901735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBA6"/>
    <dbReference type="GeneID" id="71982465"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02587"/>
    <dbReference type="OMA" id="ASWNTEN"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03700">
        <property type="entry name" value="EF2_snRNP_like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="17"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="845" mass="94218" checksum="92EA7D6DC39B963B" modified="2023-09-13" version="1">MVNFTVEEIRQLMDRPKNIRNMSVIAHVDHGKSTLTDSLVQRAGIISAKNAGSARFTDTRADEQERGVTIKSTAISLYGQLIDDEDLKDLPKVDATEENHFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIRPVVIINKVDRALLELQLSKEDLFQNFSRVIESVNVVISTYYDKALGDCQVYPDKGTIAFGSGLHGWAFTVRQFATRYSKKFGVDKVKMMERLWGDSFFNPKTKKWTKVGTHEGKDLERAFNQFCLDPIFRIFDNIMNFKKDQIPTLLEKLEIKLANDEKDLEGKQLLKVVMRKFLPAADALMEMMILHLPSPATAQRYRMETLYEGPPDDESAIGIRDCDPKGPLMLYVSKMVPTSDKGRFYAFGRVFSGTARSGLKVRIQGPNYVPGKKEDMFIKAIQRTILMMGRYTDPIEDVPAGNILGLVGIDQFLLKSGTLTTSETSHNLKVMKFSVSPVVQRSVEVKNANDLPKLVEGLKRLSKSDPCVLTYISESGEHVVAGAGELHLEICLKDLEEDHAGVPLRVSDPVVQYRETVAGDSSMTALSKSPNKHNRIYVIATPLAEEVAKDIESGKIGPRDDFKARARILADDHGWDVTDARKIWCFGPDTNGANLLVDQTKAVQYLNEIKDSVVSGFQWATKEGPVAEEPMRNVRFNIMDVTLHTDAIHRGGGQIIPTTRRVLYAATLLADPGLLEPVFLVEIQVPEQAMGGIYGVLTRRRGHVFEEAQRPGTPLFNVKAYLPVNESFGFNADLRSNTSGQAFPQSVFDHWQILPGGSVLNKECPPGKIVEDMRKRKGLKPDVPGYENYYDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBF3</accession>
    <name>A0A9Q8LBF3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02631</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758713.1">
        <property type="nucleotide sequence ID" value="XM_047901779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBF3"/>
    <dbReference type="GeneID" id="71982509"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02631"/>
    <dbReference type="OMA" id="SIVDCEY"/>
    <dbReference type="OrthoDB" id="5321960at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF46">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="710"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="758"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="817"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="869"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="916" mass="103951" checksum="7B818007A40621AA" modified="2023-09-13" version="1">MLPSLAAKMLATREQPYGVRPITASWPIADIIYVAFVAPVMLMALLEWWLLLLGFLYCFWKVYWKADENKWTVRIMAIVQATWLICIRLIFLAVMMVTLPLPPQVVQYFPPRMVSILQWFAFYTFAGLLVGPWLLCVFHLTTHYVGRKKRTRAVLDAYAAPKVVIVLPCFNEKPEVLLRTVNSIADAEYPPSCMHIFLSFDGEQEDELFLSTIEKLGVPITLDVYPRSIDIAYRGLRVTVSRFKWGGKRHCQKKTFNLIDKVYEEYLRKHDNLFMLFIDSDCILDKACIANFMYDMELKPGGNRDMLAMTGVITATGEISWKDLTKSCLTILQDMEYVHGQLYERSVETACGAVTCLPGALTMLRVSAFRQLAKFYFADKADQCDDMFDYAKGSLGEDRYLTHLFMVAAEKGYQLGMCTSAFCKTDAVETYKSLLSQRRRWFLGFITNEVCMLTDTRLWRRYPVLLIIRLAQSTIRTTALLFFIMVISLITTSQKVANLPFGFIAVSLGLNWLLMFFFAARLGRLKMLLYPVMFVVNPFANWVYMVYGCLTCARRTWGGPRVDAIKADEKITPEQAVAEAKGKGDELNIVPETFKDVAPLGRKKSVRTAPLLPSSKLEGRFALPEQTNGGYYAQRNDSIELHPDQTSILDDEQVYYHQGPRRGSMAASSYFGSHESFAMPRRVESVWDLQNILQYHAQQREQAPAGGAYFEAPQDHVGQDVPLPDYRNPRPELSHRPADVHREPEGKVPQFSNGPLPQRRDRSVDSARSAESDESVPMHFSVPRRGSSEFPRRPQSPPQFAPRVHMPSRPTDIASGDTLTVPSASYHPSTRFTPAGETSAARTGRSPLARKSFTRLATDDAPSTAGTRTEVEVRQPTRPSTDEERRGRRRRRTSVGADGRRRLSKAHRSSRSSSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBG9</accession>
    <name>A0A9Q8LBG9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="12">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_03254</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="12"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758671.1">
        <property type="nucleotide sequence ID" value="XM_047902402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBG9"/>
    <dbReference type="GeneID" id="71983132"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03254"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF11">
        <property type="entry name" value="EXOPOLYGALACTURONASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO14305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="12735" checksum="E1F9BAA2CBF0EBE5" modified="2023-09-13" version="1">MSIGSLGKDPAKFVNVSDIYFDDMTMIDTVYGARVKSWVGGQGLVKNVTWNNIRVYNVSFPIFVTQTYLDQSAKEAHNRQNNATVNMEDFAFKDWVGTQAGYQYGDGTCVTDPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC70</accession>
    <name>A0A9Q8LC70_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07761</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759099.1">
        <property type="nucleotide sequence ID" value="XM_047906909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC70"/>
    <dbReference type="GeneID" id="71987639"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07761"/>
    <dbReference type="OMA" id="SPFFMNA"/>
    <dbReference type="OrthoDB" id="5553476at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000008">
        <property type="entry name" value="Orotate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="12">
        <location>
            <begin position="56"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="26126" checksum="88B91F17F3AD3A93" modified="2023-09-13" version="1">MSSSQLPDWKQSLIETTLSSGILTFGSFKLKSNRISPYFFNAGLFCEGHLTRSLSQAYAHALDNYSREHPDFSFDVIFGPAYKGIQLCATTAYALADIDEKYGRVGHTYNRKEVKDHGEGGLMVGKSLKGKKVVIIDDVITAGTAIREAISMIDAQGGTLAGIIVAIDRQEKMPSQAEKDGQPDDGTPSGSAIGEVRRETGVPVLAVLTLEDMINGLNQLGKQDEVARMQEYRQQYAASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCJ2</accession>
    <name>A0A9Q8LCJ2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-methylsalicylic acid decarboxylase atA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759075.1">
        <property type="nucleotide sequence ID" value="XM_047907808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCJ2"/>
    <dbReference type="GeneID" id="71988538"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08660"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="296"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="45870" checksum="2FD2F9AAC670CBAC" modified="2023-09-13" version="1">MGSMEHSKISLAVLGGGIAGLALGVGLSKNPNVDFHIYESVPEYKDIGAGLALHLNAIKAMTLIGDEVKQAYFDKALNMGEADVEMVTQVILAQGPNSGELVAELGRAKGRKTVARHELMKGFMELLPKGSISNGKRAEKIEESDKGVTVYFTDGSKVEADGVIGADGVHSITRSHILGANHPAVGAKNHNGYQNYRRMMSMDEARKYGIDEKWTKFVPILCGPRGNVNSMPLAKGQKLSVGLAVRGLRFEADKYSGAPPLKDQLHLFDDYSEEAKNMVRMVADDTSGSWSYADHDHAPTYYKGRVCMIGDAAHAMHPFAGQGAAQALEDCAVMTHLFSRVDSPAQVEQAFAAYDKVRRPRSQHQVDLSRKHGDIYNYAADGMENDPDAMRAFFKESASFSNNVDLQAQNDDAMRVFEALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCV2</accession>
    <name>A0A9Q8LCV2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758759.1">
        <property type="nucleotide sequence ID" value="XM_047901550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCV2"/>
    <dbReference type="GeneID" id="71982280"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02402"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="24779" checksum="0E4FE5EEE4B99263" modified="2023-09-13" version="1">MDMFRHRDAPILQYPTFHSTIVVSAEGKHYKITNVLFDSGASSNFISRKLCKRFGLKYYPFIADMTFNTANGQVQHTEEVDLTISIAGVFQNLSFIRQRGLHHHHFTIILGTPGFWKYQLQMRWGFGAKRETLVTIEADSTLQPNVQERNIVVEAEQRHGPSMVIELKDMAVQNEALKLGETVEQRQERQGAEAAAVSRALQEVEMSRAIEDALAGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD62</accession>
    <name>A0A9Q8LD62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase pytC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759565.1">
        <property type="nucleotide sequence ID" value="XM_047907758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD62"/>
    <dbReference type="GeneID" id="71988488"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08610"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="30406" checksum="C8058AC9A210AD18" modified="2023-09-13" version="1">MVGATIEIPALLGLNITYPRMNLNRTARTCIIRSSWTPSMESSIFRLSGTMYVRNVLDLGTGIGTWAIDFADEHPDATVIGTDLSPIQPPFVPPNCHFFIDDFNANWAFDERFDFIHARSLVGCSKDFPALIRQAHDNLRPGGWLEMSDIQVPFLADDDSLMGTCISEWNSKQPEACSRGFENVVELRHKWPVGTWPQDKWYKKLGGMTRLNFLSGLEGFTLRLWTTVLGMEPAEVLVFLAHVRKDILDSSIHCYWPVYCVYGQKPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDB1</accession>
    <name>A0A9Q8LDB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Programmed cell death protein 6</fullName>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO15129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759495.1">
        <property type="nucleotide sequence ID" value="XM_047907811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDB1"/>
    <dbReference type="GeneID" id="71988541"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08663"/>
    <dbReference type="OMA" id="YNKSYNP"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
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    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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        </location>
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    </feature>
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        </source>
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        </source>
    </evidence>
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</entry>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="105"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
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    </dbReference>
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            <end position="29"/>
        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="18735" checksum="043C06F62F492903" modified="2023-09-13" version="1">MDDQGPPPTTFEAILDIAPPSPQPESSWSPLRMHQTLTLLDALRTERGYLKEVYDDAVRNNDLAFQAELRAELSSNRETTAELENLLTLVDHRVLSPGDPRPDHIGLAFKLAGVGPEAPGGEYYGTGYDNGPDKFEGETIEIDLSGVVALWNSSALNSWVDEEVGPKGESAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LES3</accession>
    <name>A0A9Q8LES3_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71984620"/>
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        </location>
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        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="18888" checksum="A5393B3FBD4CFE34" modified="2023-09-13" version="1">MATVAKPLHPGALDDPMASSQPAVSRQSSTSEHLAQISGAIIEAHMASDFAVPGSAAWQLIHAYLDEDFVMVNAAVHECPIPSARSLAEHTKNVKAFKRQNPHWSIQCYNPTAMIQRGSEHGAVLLTVRESGCEGKTVFSRDSVSMMHWKRNSNGAWICYRHSALRGGAYSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY2</accession>
    <name>A0A9Q8LEY2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-L-rhamnosidase</fullName>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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        </lineage>
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            <authorList>
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    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="156" mass="17738" checksum="93DD668B892635B9" modified="2023-09-13" version="1">MIYQACFVHTHRAESTVQWRVRCCVEKGLLTEAEYNANLTANSKSPNTITSQPYDTSKASVLSASTEPKPKRTGGHQGSTYWSADEDNIVVSTDTQGLGPKETWRTYFSQNRTYAAVRKKHDYLRRKGRLLSDRNRRAPMAHPRAWVSESMAQKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGE4</accession>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="926"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1171"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1261" mass="133534" checksum="4F7447E1627CEE84" modified="2023-09-13" version="1">MASTSETASVGPGEMACPDPSVHHHQHKLSEQASTAALYATNPSRRQQDGRESRSENPLGPDGKLSSKSAATSLRYAKPQDLPSFPTAGLTADNAGKAALLAEDYKMKELWQPEQSLAGSKAALLAQKKGGKLDLWEATSSKEGLSAAKLAVGNKMTINAYGGVDAENKSKALQAATMSVNKGRSRATSTPQPVHPEYPDSQNATANALGAAVASHRKMGAAGWDDEANQSARIGNLHKPVRGQFTDHIEYDPDPDDTRHQAALRASAVAAAKGIYQNQNRSKLTDEPNTANLAGAQAAAGRSSTSAAPPDLKQQALQYMSLQGAAQKLAAERLAKIDKDTENARYREYYGYGDDIKSKRLSSRMSMRSVGTGRQRKRASSDGGRNYSDDSDDEAQAQRIRTQMAQLSTATGKVDQRKQQDDRAKLLAAAEKRVSARMHTMDEKVLADTGKVPPSLMEDWEAKARERAQKQREEAASHPGKTHVGGGRFMDDADIEAIAAARLKPTLDQLNANAENRRGREEELRLEKEEQDKEKRDEKQKTREEKERVKKIVAEDKAAEKARKDEEKARKAEEKRLEKEDKRKSREQKRDTIVVAPTSADASKADDDDGNAVEDPAVAKHRSALGRLKDRFSKSNKEEEKPDNELEKVETAEVKKERPATAASTTAVASGIPGNTTSGGTATDGSVSPVTPADETAVVQPQPIHPHQTERSAVLDHQDAPVPPAMPIAPLTVPEQHDAPLTAQNTTSDKGTEDGADRFHKATVPGAAGVTAASVPALAVNGNETDVDTATAPARAGFEQHGGLSYREETQPTQLGSHMPDLERHISAIPDSDDSDDEWDSDEERPTRNAGAVAVPTTQAGVAEQDHSKAAIGAGVGAGAGVATGELGEDKTQEIVDRVNAAPVKNDTTQSPVSPIDPPTQRSVEPTSTTVHSPTTTTTTRQEPSAKPAAQQDPIASSSAGPTDTQHPKASIDEAVAHVAETKFGTVDDKPSATALGTAVFGQPKGPAGPDPKPAKLQKSGGPVEGVGTTANTSVDSGKLHKEQKAGGESKTTTKSEKEGKGFRGFFNKLRNKESKGENKYPDFKSPERGESSKNVSYDSTKAGDKPITTGTTSGVPAAGAIGTGAEGASATKTADAAPTLGNVDTGPTFSSGAEPDSPSSYQRGGAGLADLDDESSGAEEEDVTRGRAGRSKAGKKMGFGSSRTSGAKDTTADRQNSSTEDETFEEARDHFDESLAPPPAFAGQAKSESPSRGTRFQEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGQ9</accession>
    <name>A0A9Q8LGQ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761546.1">
        <property type="nucleotide sequence ID" value="XM_047905737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGQ9"/>
    <dbReference type="GeneID" id="71986467"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06589"/>
    <dbReference type="OrthoDB" id="3438345at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="28336" checksum="C8D1337DE49862C9" modified="2023-09-13" version="1">MSTLSISAQPYLDGLPLEVVEEIVTLLDLTDVCKFRLTSKELAAKASHGRFKTFFRHKEIDVDDLKKIESFMRMTQSGGLGCLLETLSLVRYDFPESRNVQGSSTIAAFTDCFKNLEQHSRAKSLREIVLDIWAKDDTGERCAPNRKHWRHIWLLAGALYRDAMAAVSESELLVEGLCFFATTGNCSLGFDEFASCPTFLYTPIATLKSLSLSLSSSASLIALEGQDTELASNHVEQFTSFLKLLIGLERLDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHP3</accession>
    <name>A0A9Q8LHP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spore development regulator RYP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761987.1">
        <property type="nucleotide sequence ID" value="XM_047905415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHP3"/>
    <dbReference type="GeneID" id="71986145"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06267"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="218"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="295"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="436" mass="47699" checksum="DB4BC474342E7D94" modified="2023-09-13" version="1">MMARDQVSLIVRQQPTRAQVVQENNPKNRKPIDPPPIIELKYDDRNDPSNSQWLVSPRTFMMVTLVDEKDSKQDARGESPGKLLIGQTVSSLHRLKDVTNKDGGFFVFGDISARKLGTFRLRFSLFDTIKESDEVLFMGSIESDPFPVLAQRDFGSMSESTHLTRTFSDQGVKLRVRKDTRAISSIGVKRSFNASPPDAPSPGLHSAMYGGAVQDHYSASSPAVKRQRAGSEYDTSHMYSIPGSDSHLSQYAGSIPSGTRGWTGGDTQRVPAAYGHQQSPINIGMSSRMQQPIAVQAHTPPSWSNAHSQSALPSPTPSVSNQQPPSYPTTTTQQSTSSIFGDPGTASSVPRNPYYNNSYQTYQTHSQYSGQHSGDLQSAYDLQMPGSSIPDTAGLSAAHTPGYSHSYMQPSSIYPPEPSEISGGYPYSLDEKYQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI49</accession>
    <name>A0A9Q8LI49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762268.1">
        <property type="nucleotide sequence ID" value="XM_047904938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI49"/>
    <dbReference type="GeneID" id="71985668"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05790"/>
    <dbReference type="OrthoDB" id="3646623at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="24008" checksum="876807BDDD663BCC" modified="2023-09-13" version="1">MPLQKRGTSLQYNNSATMFSAYNGPVKTYQVVNTKAFNTRHLQIRHNNRPLLWAETKRSFFSAPQTNLHKGSMNGPVVAAVKLRTMSSSFLVAYGDAVGRDLWEKVQSGIFSNKQYGFMLQGRHFCWRRTHDKFLGASRMGSQDFKLLDAANDKVLAAYMNQNWSMSSGDGRIDWYVELGQALEIMAIPVLLGLEMRIRAAHAAGAAGAGEGGGGGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI88</accession>
    <name>A0A9Q8LI88_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">uS12 prolyl 3,4-dihydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_06038</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54160"/>
            <dbReference type="Rhea" id="RHEA-COMP:13817"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
            <dbReference type="ChEBI" id="CHEBI:138052"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[ribosomal protein uS12]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54156"/>
            <dbReference type="Rhea" id="RHEA-COMP:13816"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762328.1">
        <property type="nucleotide sequence ID" value="XM_047905186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI88"/>
    <dbReference type="GeneID" id="71985916"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06038"/>
    <dbReference type="OMA" id="GWYHIPQ"/>
    <dbReference type="OrthoDB" id="430522at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009896">
        <property type="term" value="P:positive regulation of catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010604">
        <property type="term" value="P:positive regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000014">
        <property type="entry name" value="Prolyl 3,4-dihydroxylase TPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.20">
        <property type="entry name" value="Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019601">
        <property type="entry name" value="Oxoglutarate/Fe-dep_Oase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043044">
        <property type="entry name" value="TPA1/Ofd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039558">
        <property type="entry name" value="TPA1/OFD1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13661">
        <property type="entry name" value="2OG-FeII_Oxy_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10637">
        <property type="entry name" value="Ofd1_CTDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="14">
        <location>
            <begin position="140"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="282"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="474"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="596"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="609"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO17962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="621" mass="69346" checksum="49FEB7D03D80B9B8" modified="2023-09-13" version="1">MKRRADDNQANGNGSNKRPATEQSAIEKFRSGLFDPKSVKSYANEYVESGPYKHAVIHELMNDSLLRDVRNEIVENIEFTPKETDIYKIHQSGDLANLDGLPASALEKLPSLLKLRDALYSYDFRQWVSMVSGAGALSGKKTDMAVNVYVPGCHLLCHDDVIGSRRVSYILYLTNPDKPWKAEWGGALRLYPTDEIKDQEGKTFKLPQSMWTKVIPPAWNQLSFFAVQPGESFHDVEEVYHRGAGASEDDGGRVRMAISGWFHIPQEGEEAFEPGLEERLAEKSSLQQLQGKADEFDEPQHEWHDPSHGNKTSEGEDDELTESELDHLIKFMTPNYLTPETVEELNELFSEESVLQLTDFLSPKFSTALRTALESHSEDAIAFKTSRPPHKHRYQYLHASTTSPPDPDSPLKQLLNELLPSLAFRKWLSLVTGLSLKRCSILARRFRQGLDYQLAQGYEGEEPQLEFTLCITPSSGWAPDEEPQAEGGASNDAKPTASAEEDNVGGYELYMAGDDEEDDEGSDDGVTIPANVQSHTGAGQRRSAKKREADPAVYQAAADDEDDGILFSNPAGWNTMSIVLRDKGTLKFVKYVSQKAPGARMDVTGSYEVEPEDDDDEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK9</accession>
    <name>A0A9Q8LIK9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor spt8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05636</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762414.1">
        <property type="nucleotide sequence ID" value="XM_047904784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK9"/>
    <dbReference type="GeneID" id="71985514"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05636"/>
    <dbReference type="OrthoDB" id="10260946at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="137"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="517"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="324"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="467"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="698" mass="75050" checksum="5D201F278965274F" modified="2023-09-13" version="1">MILCNMAAFDDDNDPATGSQDEDENEDEEMEDVNEANHEDDQDMDAGGDDDDEDEGDDDNDDDNEDEDDEDKNEPESPSQRASQHTATRGAADEEGAKQSVVVASNSPRTSSGRSPGSSGVSWIPPTRSLALTAQAYDIVPTMAAPQGTSINAITATPDMHYVFSGGTDGYVRMYNWVDTANGKVPLTVAQKHPFVDSVMKAGSLITYWENEESNYLKTPPSQPDEGKWTSPVYSLAVQHQALWLLSGLESGGINIQTCRHQAGTRITTLKEHTSAVSVLQLSRDETSVLSGSWDKNIHDWDLNSGKVKRSFKMSGSQIGAIEVRPTSDLAVPEVTETQPDLPSDTFSSNNADKPTQNGSMSLNQSRRQSGKGDEDAPGSPEGSLFGEGDHGSLFGEDPAGGAGGGNSFGDDDDDLTKALEDEMQGSEKGAASDMDTALMNASNGDAAIPACASEDIIPELAEAAWQPEQRNEEGASGSTDLHANGIVTNGLPHSDEPLTAPPTNEDQQYSVADLPTQSESTFLDAAIDGTLRIWDRRVQQPVAAIQPVGSTPPWATGACWSPDGNFFYVGRRNCTVDEYSIHHLGSKRSEANRNFKFQQGSGPVYAVRAMPNKKHLVCASQDILRIYDLAQAESRHKTVPFTIVPGHRGGVISAIHIDPTCRFMLSAAGNRGWEGNGTEVLLGYEIGVQDDKGVWHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIN1</accession>
    <name>A0A9Q8LIN1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762444.1">
        <property type="nucleotide sequence ID" value="XM_047904943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIN1"/>
    <dbReference type="GeneID" id="71985673"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05795"/>
    <dbReference type="OrthoDB" id="5350410at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="545"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="63220" checksum="F9325D4F1C3F3572" modified="2023-09-13" version="1">MSLPKRSSFPHHSSLPAKGDTTAAGQHANQQHHRQAGVLANIMPATKRKAQSAAAPSIDAVLDTPAAPTPSNHSHPSWIGPQPVARVPTPGSIIMKIPVTIEFSSPGLQPPVFVSSSLNGWQPTEMECTKSEHGRYSFSKTFTAEEGEYQYKLRLGPGDWWICDTTKPRVDDGAGNENNLVVVEPKSHTLYAADEREPHPQEEYQHDEPPMMKHEAFTTGHTTHGAHGHHDIDHADHDHLTPDHHVASPLFRHESIAPTPQHHAHPHDYNEHWPEDAPLLRHESIAPSSHEQSHSPLFGHESTAIDNKGDHDVRHHIPPMHLGQQRRGSLGERTGSNRSIPEEADPDDPSLEKFPTDHVGIMEHLDRVRRASDSGSERSSSRSPSNSAVASASPMLPAVKEGEEEEDLEDLKDGAGDKPQTHTQEHLDRPAAPITPPMTPKSEDSKDKDDSPLGIREQADAVKKSLKEVHVQEKLDQAKSLIDQHTPVVIEKAQQAQQVIQDNVPQSVIDKAQQAQQAVQDSVPVVKDKVQQAKDVVVESGNKGLGLLAIGLGIAMAIGSAALAFWLIKTKSEDVVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIS9</accession>
    <name>A0A9Q8LIS9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Squalene monooxygenase</fullName>
            <ecNumber evidence="16">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_06476</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Endoplasmic reticulum membrane</location>
            <topology evidence="3 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="16"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762542.1">
        <property type="nucleotide sequence ID" value="XM_047905624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIS9"/>
    <dbReference type="GeneID" id="71986354"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06476"/>
    <dbReference type="OMA" id="AKRTFYW"/>
    <dbReference type="OrthoDB" id="1678617at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000166">
        <property type="entry name" value="Squalene monooxygenase Erg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 16" id="KW-0274">FAD</keyword>
    <keyword evidence="5 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="19" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="12 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="17">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene epoxidase" evidence="18">
        <location>
            <begin position="204"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO18176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="505" mass="56056" checksum="2AD0B6BC9BFF6214" modified="2023-09-13" version="1">MSVSILTHDAPKSLRFRAREQREMHHEADVVVVGAGIFGCAVAYALGNQGRSVILLEKSLQQPDRIVGELLQPGGVQALEKLGMRDCLEEIDAVRVLGYDVIYYGEEVRIPYPANARDDTAEAAKEKDYTDELRGMKRKRPEGRSFHHGRFISKLRRKAMSCPNVTVVEATATHLIRGEHTGHVLGVEATVNERQPNERHDSYFASLTIVADGYASKFRREFRKDAPVVKSKFWGLELIDAKLPMPNHGHVVLGEGAPLLLYQIGTRETRALVDIPQDLPSASVANGGVKGHLKNVVLPTLPAEVRPSFEVAIEKDRLRSMPNSWLPPTTNKAPGLVILGDAMNMRHPLTGGGMTVAFNDVVLLSELLSPENVPQLDNTKLVLKQMRTFHWRRKNLTSVINILAQALYALFAADDTQLKALQMGCFHYFKLGGNCIDGPVGLLAGIIRQPFVLFYHFFSVALYAIWIYITTGPVASLPIRAVMSAGVFWKACVVIFPYIFSELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJH8</accession>
    <name>A0A9Q8LJH8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762916.1">
        <property type="nucleotide sequence ID" value="XM_047906608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJH8"/>
    <dbReference type="GeneID" id="71987338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07460"/>
    <dbReference type="OMA" id="TEYDWRR"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="44438" checksum="480A1E788B43B232" modified="2023-09-13" version="1">MSASESISPFTLSIEQAVLDDLQLRLWLTRWPDKETVMDWSQGVPLAAIQELCEYWQTRYNWRRCEELLNSFPQFTTTIDGVEVYFLHFRSKHGDALPMVLTHGWPGSILEFRHVIDRLIDPEADGGTPRDAFHLVIPALPGYAFSSKPTETGWNYQLTARAWAVFMDRLGYTDSGWVAQGGDWGAHVTVSLGHQAPKGLKAVHMNSVYFEPQKEIQIPAKDKAGEGRAMDLDHLRDTTGYRGYSLQQSIRPQTLDYALADSPVAQAAWIYEKFRDWSHHNGDVGTIFSKDEMLDTIMLYWLSNSGTSSARYDWENKPDTTAWAIGADIAVGVSWFQGDTAYAPREWCERHWDKIVIRNEVGKGGRFAAWEQPEKFVREVREWRRNVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJP9</accession>
    <name>A0A9Q8LJP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Isovaleryl-CoA dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05554</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762299.1">
        <property type="nucleotide sequence ID" value="XM_047904702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJP9"/>
    <dbReference type="GeneID" id="71985432"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05554"/>
    <dbReference type="OMA" id="CFITNSG"/>
    <dbReference type="OrthoDB" id="9988775at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008470">
        <property type="term" value="F:3-methylbutanoyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000021">
        <property type="entry name" value="Isovaleryl-CoA dehydrogenase IvdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000003">
        <property type="entry name" value="isovaleryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000004">
        <property type="entry name" value="Isovaleryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF18">
        <property type="entry name" value="ISOVALERYL-COENZYME A DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="52"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="167"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="275"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="47382" checksum="F0B11B2427A647AE" modified="2023-09-13" version="1">MALLAPCRAALLQTSRLASRNALRPAFAAAQQERYASSRKHPQGFAPPTQADLEELRERTIEFCRREITPEIAQKTDHVNEFPNDLWPKLGEAGFLGITADEDHGGLALGYQAHCVVLEELSRASGSIGLSYAAHSQLCVNQLQLHGTAEQKEKWLPGLISGTKIGALAMSEHTAGSDVVSMKTTAKKVDGGYVLKGGKMWITNGPDAHVVVVYAKTEPEAGSKGITAFLVDTTTTKGFSVARKLDKLGMRGSNTGELLFDDVFVPEDAMLGPLNKGVKVLMEGLDLERLVLSAGPLGLMKAALDVTLPYVHERKQFGQPLAHNQLIQGKLTDMYTKYRASAAFTYTVAREIDENHDAIADGTATIKTQDCAGAILYASERATECGMDAIQCLGGMGYMNEMAAGRIMRDAKLYEIGAGTTEVRKMVIGRAFNKEYAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2R4</accession>
    <name>A0A9Q8P2R4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755390.1">
        <property type="nucleotide sequence ID" value="XM_047899603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2R4"/>
    <dbReference type="GeneID" id="71980333"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00455"/>
    <dbReference type="OrthoDB" id="3639548at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="472" mass="53065" checksum="C9C89E4FBF173F4C" modified="2023-09-13" version="1">MTSGSRLFPDAVMNGVVLSLAALKRIDLLPAAMMAVHGSLSPTVHKAIGITLRAADPQALRTMIPTALSKISKISERFVVLQQLFDGDIRKHEGSAAEAAMEVVRGILSDCSAPIVDDGYALTDVAVCLNDQAFVNDRILKLLGQRRRQTDFLLAFLSSWSTRGSAGTDLEMMATFDSVFDLLIPSFNLDVRDTQPVKRQRVDIAQPPKQSVSPSKTAADLYWVMVYLVNHEKSHQLQELCRALSSEVLLQRPEVLRSILIPYLRHAQGLAAGCLENGQQTCVLQIYFSILDAYLRMYVQKQPSTVENWSRNRVACSCSDCFKLNLFLISSMHQTERFSVSKPRRHHLHIVLDNARINCTHETERHTRPETLVVTKRDRRKGVYDAWLARCLEAHNEIKQFDQELLERILGERYEVVKDMHPIITDDANAPSFLQRPVLRERRNGPIALAPAASSRAGTKRKVEVIDLCDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P318</accession>
    <name>A0A9Q8P318_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pumilio y domain family member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755618.1">
        <property type="nucleotide sequence ID" value="XM_047899343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P318"/>
    <dbReference type="GeneID" id="71980073"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00195"/>
    <dbReference type="OMA" id="YGPEFSI"/>
    <dbReference type="OrthoDB" id="497380at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="6">
        <location>
            <begin position="110"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="175"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="642"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="676" mass="76027" checksum="FCAD903F757B4B30" modified="2023-09-13" version="1">MSKANGLKRKEAPSDARKSDKKQKTYDPKLARAEKKRSHLEQAAMDNDEDFEGLSDNDGGVTLPSNGVQSEEPKKFKLEGGKTSAEAHAEQRRVAKERKAAKPHADIIQRAKQLWERLRRKSHVPKDERKELVAELFSIVEGRVRDFVFKHDSVRVIQCAIKYARPEQLKTIVRELQNDVRELAASKYGKHLVGKMVVEGDREDKDLIIPQFYGHVKRFINHPEASWIMDDIYRQVATPKQKDMLLREWYGTEFALFGQSRPNASDEQTTSDLRMILEETPEKRKPILGYLKQMIDNLIQKQKTGFTMLHDAMLQYFLALEPGTEDHSDFLEMLKGDIDAESEGGGGDLYRNLSFTKNGCKLVCYALAYGSAKDRKVILKCFKDHVETMAYDQYAKMVLVAGLDLPDDTKMTSTSILQDLLGLKMEDTTQRFDRLSDMMTNLNSRLPILYPLAGPAKWLVNDAEKEFTGEIHKIRETTSKKAPEVRRQELIAHISAPLLEFIAERAQSLVTSSFASQAVTEILLECHDKDNTQRDAAKKAVAALAAGDPNEEGHVAKDPATGRMLRTLVSGGSFDPKTKKVVLVEPRLGFGEVLYPVIKDKLVEWACCDSSFVVVSLLESEDVPDKVKNEVKATLEDAKKQLKKAAEGEKSAKAEGGKKDKKPKGNAGARILLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4M8</accession>
    <name>A0A9Q8P4M8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757400.1">
        <property type="nucleotide sequence ID" value="XM_047900449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4M8"/>
    <dbReference type="GeneID" id="71981179"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01301"/>
    <dbReference type="OMA" id="HAARICC"/>
    <dbReference type="OrthoDB" id="3921930at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="47"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="45297" checksum="D465EDA30539414A" modified="2023-09-13" version="1">MDVSPAFPYQHLEDDHIRLIQLLPQSTGTTIECSIHHSKLEEAEDNYIALSYCWGDSTTTELITLDGHPIRVTQNLWHAYTAIVQHHDRNAYYWIDALCVNQQNLAERNHHVQRMGMVYSTAKAVHTWLGSEDHETVIAFTEIVSRANANTSTGSNPPDQRAATAVGNLASREYFNRAWVIQEFIPARNLQILCGRFTCDWTALDACIKDIETYSGVEIDYTVGANNLLGGRGAHLNAEPDTATLSHWERFYGCMMIFSQAKCFDARDRVFATLDHPWLESIPGDMLRVDYSLTKEEVMLSTLETCERIRVFEREVSSAGLSEDDQEFVEAIWQQMFLTIGQAGVDHGKRELKLFRHGVLEQHGWGCSRLPLSVSTQSGREVDCSGPVLAFLLQLAEIQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4X5</accession>
    <name>A0A9Q8P4X5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757538.1">
        <property type="nucleotide sequence ID" value="XM_047903010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4X5"/>
    <dbReference type="GeneID" id="71983740"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03862"/>
    <dbReference type="OMA" id="SIMIAKN"/>
    <dbReference type="OrthoDB" id="2830640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="460" mass="53372" checksum="515DA85C0796B8AF" modified="2023-09-13" version="1">MELQKFEISDSRLEHNNWQFPKTLKTRPLRSLEEEDFLVNHKIDRSYDDSTVRFKLLVGNAVSANLKDTDNLAIDSEVLTIVKQQGWVSDEYLHLWRRDNGGSAALTSHGILTFILQTPRDGRSFCSLSLVNRERHYCGGLYMTDENFSLNALLSSKEYINKHPKVPRDFAVLPFHILQHHVDETLSQVQDLSRQITATERRIADGRISLEDNGDYKLLNRLNLEHVRLQRRSNFEIELASNLIKYLDIYHKMWTALWEGGTGYIEDMREKVEQQTRYSEQVQRDLEMMPRRIDNQSKALFNIIAMRDNKLNIELAASSKRIAEESRLDNLLSVKLAKATADVAEQTRQDSAAMKTIAVLTLTFLPGTAVASFFSMNGMFNWEPSPGQSLASPYLYVFFVVTIPLTIIVYVAWWYWFRRAQKEFQKNYETSDFAAVEQDLLKRMRTATNSWQTTGRHPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Z6</accession>
    <name>A0A9Q8P4Z6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fatty acid hydroxylase vlmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757745.1">
        <property type="nucleotide sequence ID" value="XM_047902937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Z6"/>
    <dbReference type="GeneID" id="71983667"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03789"/>
    <dbReference type="OMA" id="NCELMIE"/>
    <dbReference type="OrthoDB" id="6354873at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="190"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="41794" checksum="56A4283357EB560A" modified="2023-09-13" version="1">MSTTTTTITAPAVPVTIDRRPKDSMKSTWRKDETQWGFYHKFLNLLNVFHIDDDKEVPIHAKTDKMPYLTEWSCNVWILYHAAWPIALQYAWNAATGRDMHSIAVFLLFTVAMQLNSIHEVRVLRRLGHRFGFLDGDKHERDDVPDVAVAKVFSSLQLTTTVRPALAVLLAYSASNSMSLSWWLPLELGLYAIVLDGFFYAYHRSCHELNGLWQYHRTHHLTKHPTPLLSSYADHEQEVLEIALIPLATYVVLRYGLGLPMGFHDWWVCHEYIIYAEAFGHSGLRVWSTTPGTASWFLKAFNCELMIEDHDLHHRKGWRKSHNYGKQTRLWDRIFGTCGKRIESVEGNCDMDNKFNFPLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P582</accession>
    <name>A0A9Q8P582_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-alpha-glucan-branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycogen-branching enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_03698</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758226.1">
        <property type="nucleotide sequence ID" value="XM_047902846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P582"/>
    <dbReference type="GeneID" id="71983576"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03698"/>
    <dbReference type="OrthoDB" id="196493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000001">
        <property type="entry name" value="1,4-alpha-glucan branching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000250">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000003">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF3">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="13">
        <location>
            <begin position="219"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO13860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="711" mass="81852" checksum="B8D0A6254F3376AB" modified="2023-09-13" version="1">MDKLNEASADSVMAKPASDQVRNDGTGVVALDPWLEPYSGALRSRFTKAQNWIKTIEKTEGGLEQFSRGYEKFGFNITQDGTINYREWAPFALRAYLIGDFNGWNRDSHEMKRDPFGVWEISLPPHNGQPAIPHDSKIKISFVVPNDQARQERIPAWIKRVTQDLSVSPVYDARFWNPPTKYQFKNQRPPKPQSARIYEAHVGISSPDPKVATYKEFTQNTLPRIRDLGYNTIQLMAIMEHAYYASFGYQINSFFAASSRYGFPDELKELIDTAHGYGITVLLDVVHSHASKNVLDGLNMFDNSDHLYFHEGARGRHELWDSRLFNYGHHEVLRFLLSNLRFWMEEYQFDGFRFDGVTSMLYTHHGIGTGFSGGYHEYFGPNVDEDGVVYLMLANEMLHNLFPNAITIAEDVSGMPALCIKLSLGGIGFDYRLAMAVPDLYIKWLKEKQDIDWDMGQLCFTLTNRRHGEKTIAYAESHDQALVGDKTLLFWLCDAQMYTNMSVLSEFTPVIERGMALHKMIRLITHALGGEAYLNFEGNEFGHPEWLDFPREGNGNSFHYARRQFNLPDDELLRYRFLNDFDKAMQWTEEKYGWLHSPQAYVSLKNESDKVVVFERAGLLFIFNFHPSSSFTDYRVGVEQAGTYKIVLNTDEPKYGGLNRVQNDSRFFTTDFEWNGRKNFLQVYIPTRSAIVLALEETLDSNWKSNVSLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5C3</accession>
    <name>A0A9Q8P5C3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carnitine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03834</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758122.1">
        <property type="nucleotide sequence ID" value="XM_047902982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5C3"/>
    <dbReference type="GeneID" id="71983712"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03834"/>
    <dbReference type="OMA" id="HILVMRR"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.20:FF:000003">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000019">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000025">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000003">
        <property type="entry name" value="Carnitine acetyl transferase FacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.20">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042572">
        <property type="entry name" value="Carn_acyl_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="10">
        <location>
            <begin position="47"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="568"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="705"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="714"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="744"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="781"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="807" mass="89501" checksum="7BD3AB917C9BFBE7" modified="2023-09-13" version="1">MAERSAENAKESLQDHSEDKQNPLASHTNPNSKPGITFAAQDKLPKLPIPDLEATCQKYLESIDPLQDAREHHDSERAVQEFLRTDGPALQAKLKAYSEGKSSYIEQFWYDSYLNYDNPVVLNLNPFFLLEDDPTPARNNQTTRAASLVCSALSFVRAVRKEELPPDQMRGQPLDMYQYSRLFGTARIPTENGCQIGQDPAAKHVVVLSRGQFYWFDVLDDNNDLIMTEKDVSLNLQVIVEDAEQTPVHSAAKGALGVLSTENRKIWSSLRELISKDEGSNNSDCLNIVDSALFILCLDDTEPNNSADLSANMLCGTSIIERGVQVGTCTNRWYDKLQIIVCKNGSAGINFEHTGIDGHTVLRFASDVYTDTILRFARTINGQAPSLWASQSPDPSKRDPKSFGDVSTTPHKLEWDMVPELATALRFAETRLADLIQQNEFYTLEFDEYGKNFMTSCGFSPDAFVQMAFQAAYFGMYGRIESVYEPAMTKIFYHGRTEAVRSVTNESVEFIRTFWADTSPAKKVEALKKACEKHSALTKECAKAQGHDRHLYALMCLWQRQVDGDAEVNSLNGDGGSVNGWSSPTSDRDPTSSSASPNRDSTMSDEGSIQSTSPPRQQITLPALFADAGYDKINNTILSTSNCGNPSLRHFGFGPTSGEGFGIGYIIKDGSISVCASSKHRQTRRYIDALESYFLEIRKLLRQTQRRGTGGDKNASRAREAEEQRPKGTRLKSRGRLVVGEQVGGAAAPSADDSGMASDDEFGGYGFFDAGMLQQALRANKGSEEERPSEKVQARREVGKKLRLMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5N3</accession>
    <name>A0A9Q8P5N3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02737</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758303.1">
        <property type="nucleotide sequence ID" value="XM_047901885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5N3"/>
    <dbReference type="GeneID" id="71982615"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02737"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="266"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="640" mass="73701" checksum="FC6A0C8FCCCF9BAB" modified="2023-09-13" version="1">MVDVISRIFNPDDNDRRGLHGELSHLLPRHREDNLVSAIPAKDVTLTALRIKYQLEQVIPCELPEDRITAPHSHVITPAVIETTKSAGKVSGSNEDHGACVIYCLLIVKSWFQKQSLFELWDADLHVLRATACEVLAKHIIEDEEDNNHLMQEVLLKRYSIVVDGEDTKPANAIEKAVDLHAVRVIGSSGYQKCISYLWRGWLVQDDNDPSRFVDYKLKASTNYWDHFEPDRMRVPQYQNALQVILSLIFLGLYTGAINTINPGGELDVVEGMLYIFTLGFICDEATKFFKIGRYYFGFWNMFNSTLYILLAVSFVLRTIALAHPWKSDTRFYYNTQSYNFLAFSAPMFWMRMLLYLDGFRFFGAMLVVLKVMMKESIIFFALLIIVLVGFFQGFIGMDQVDENIDATQFITKAMLNAIMGSPEFDNWDNFQPPFGLILYYIYNFVIIVILLNVLIALYNSAYEDIYENAIDEYLALFAQKTLQFVRAPDENVYIAPFNLIEIFGLIIPFEWWLPRHRYEQLNDLVMGVIFSPLLCVTALLETRTARKIKFNRSRHESDDDTIEEWEQLEGEMDVEGSGWSKRVKETSPNVVTDATLLEVRELREQMKELKEMLRELTLGPEQSQSRIGDSTYGEADGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5N8</accession>
    <name>A0A9Q8P5N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GATA type zinc finger protein asd-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03552</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758467.1">
        <property type="nucleotide sequence ID" value="XM_047902700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5N8"/>
    <dbReference type="GeneID" id="71983430"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03552"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056998">
        <property type="entry name" value="Asd-4/GZF3_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25026">
        <property type="entry name" value="Asd-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
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    <sequence length="394" mass="41409" checksum="96F0068147480AFF" modified="2023-09-13" version="1">MLQYAAPSAPQHFPTGPHSTVHHNDFEIARPPSTASHHSYESIRQSSLNGLGAGTAGAGNGSSSLSALAACAAQAPIAVASQGSAEGSTRSSTPSNSAHMSTQPAHFSAPASTSSNVAPVCQNCQTSTTPLWRRDESGSVLCNACGLFLKLHGRARPISLKTDVIKSRNRVKTAGPKKRDSHGGGDGMAHASNGYPAAHPDLAHAGHHQHPQHHQHGMPMGMNGEHHRVPSPGSGSNGDSNIGPHNPNIAPQHIFDTVTLPPDTFASPSLPQFSLRQPSPSTSALNGNSTNHNDGSQSYDALIEQNKQLSTRANELEVINGLYQGRVRELEAHEEEARRQTQSLHAELAAARARIAELEAEDSPARKRVKMNNDLGDRSGNSTPAVDSGDGTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5R5</accession>
    <name>A0A9Q8P5R5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA ligase</fullName>
            <ecNumber evidence="16">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_03884</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
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        </reaction>
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        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 2"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_ligase_A_C"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_LIGASE_A1"/>
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    </dbReference>
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        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 16 21" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="19">
        <location>
            <begin position="431"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="20">
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        </location>
    </feature>
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            <end position="983"/>
        </location>
    </feature>
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            <begin position="58"/>
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        </location>
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        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="984" mass="112589" checksum="ADE8163CE18A82CC" modified="2023-09-13" version="1">MAEDDDVEMQNPEAAEEEHMMYGHGTMTEQELDEKYPNRPHNHSKTLPFHELFTHLFNPLNDNKKKPTGPAQARKKVGTDGPRNNPNEIRRSIIDRFIGRWRKEVGNDIYPAFRLIVPEKDRDRGMYGLKEMTLGKLLVRVLKINKDSEDGYNMLHWKLPGAESGSSTAGDFAGRCFNVISKRPMRQTPGDMTIAEVNELLDRLSVAQKEENQRPIIEEFYNRMNAEEMLWLIRMILRQMKVGATEKTFFDIWHPDAENLFNISSSLKRVCWELYDPDVRLEGDDAGICLMQCFQPQLAAFQMRSMEQMVAKMNPIEEDPVFWIEEKLDGERMQMHMIEDENMPGGHRFGFWSRKAKDYTYLYGNGFEDDNAALTRHIRDALKDGVRNIILDGEMITWDMKEDCVVGFGTLKTAALEQQQNPFAGGHRPLFKVFDCLYLNDKDLTRYTLRDRRKALTSSITSVKRRLEIHEYQEAQEASEIDLILRQVVAEASEGLVLKNPRSPYRLNERNDDWIKVKPEYMTEFGESLDCVVVGGYYGSGKRGGGLSSFMCGLRVPAVIFEAFPNTNPQKTWSFFKVGGGFSANDYAEIRHRTDGKWIDWDRKKPPTDWLELGGGDRQYEKPDVWIKPEDSVVISVKAAQVGGTEQFRLGATLRFPRFKKLRTDKDWTQALSVDEFIALKNEAEHAKEEKKFKIDEARKQRTTRKRKRALIIQGQEDEVTTPYAGPATKVFEGLSFFVMSEAPNPIKKSKAELEALIKANGGNIVAAETDPHTILIADRRVIKVASIAKRDERNIIRPSWLLDCVKQSEADIGRPGLLLPFEPQHLLHTMSSEEGRYDDNVDEYGDSYARDVTPEALLQLFKSMPSKVEDGFEPAEILDQLNDHGHELDAMPGWMFHGVTAFFEDVAFETTRLFEFAGGTVADSIEDDLVAHVVVPKGDAGAARRMRKAIANKKQLPRIVSHDWVTDSWAEGTRLDEERYAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5W2</accession>
    <name>A0A9Q8P5W2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylcoumaran benzylic ether reductase PT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758543.1">
        <property type="nucleotide sequence ID" value="XM_047901709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5W2"/>
    <dbReference type="GeneID" id="71982439"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02561"/>
    <dbReference type="OMA" id="AHEKPHQ"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF11">
        <property type="entry name" value="ISOFLAVONE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G12510)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="35370" checksum="1819A528B4E633A7" modified="2023-09-13" version="1">MAATTKNILIFGGTGLIGQHITDAILRNKDKFSKIAVFTSKDTLGAKSDKIDSLKARGAEIIVGDTQSSTDVNEAYNGFDTVVSCLGRPVIDRQLQLIELADKHPDIKRFFPSEYGTDIEYWESSANEKPHQQKLKVRALLKTVKNLEYTFVVTGPYGDADGLLYLAAKKPEDEAEGTFDVKRKRAVLLGDGKGKISLTTMRDVGKLVVAALLKPEAVKNKAIHVNSFTATPEEIVVEFEKQLDAKWDVAYYSLDQLKQLEEEAWAEGLPKAGTITLRRIWTSGGTLYDKRDNYLVDMEDRVDSLADAVRQAIAIQQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P652</accession>
    <name>A0A9Q8P652_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759049.1">
        <property type="nucleotide sequence ID" value="XM_047907290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P652"/>
    <dbReference type="GeneID" id="71988020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08142"/>
    <dbReference type="OMA" id="IAGCSYT"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF2">
        <property type="entry name" value="ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO14683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="50803" checksum="C44C6A91F2023CC8" modified="2023-09-13" version="1">MAGFFEGDKVASQISMDDAFEHTDLPPEKAGTAFDRRDMARMGQAQEFRRNFSFIPIFGFAAVLMMTWASTLSSVSYILPNGGLPAMIYIYIVTLFGFGAAILSMAEMASMAPTSGGQYHWVSEFAPKSFQKLLSYLVGWFCVLGWQAGIAGQCFTVALQVQGLIILNDAAYVPQAWHAVLLTIAACSVAVLFNTFFARRLPLLEGLVLILLVFGFFAILIPLWVFAPQHSNADVWLDWTQTSGWPSMGTAALVAFTGPIYALIGPDSCVHMSEEVKDASRTIPWAMVSTLCLNGITGLVMTITFAYCIGPIDQATMPAYNFAFIGTFYNATRSHAGATVMACIITTLTLCSAISNVATASRQMFAFARDGGLPFARIWCYVRPGWDIPLNAVMLSFTITCLLPLINLGSSVTFNAILSIGVVALLTSYMTSIGCILLKRIRGEELLPRRWSLGVPLGWASNMIGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6A8</accession>
    <name>A0A9Q8P6A8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759214.1">
        <property type="nucleotide sequence ID" value="XM_047907568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6A8"/>
    <dbReference type="GeneID" id="71988298"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08420"/>
    <dbReference type="OrthoDB" id="10497917at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="193" mass="21505" checksum="352472220E06661F" modified="2023-09-13" version="1">MVEEGLLKITPGLIQTLQTARANSHYLRGMSTYAAYPHVDRASRFQVAAGMMVSIEVRAMEHEIEPFRTKYWKKSVLVLPHDFPAGEVLNHFKAQFECVADTDFDANAVYSDIAAAAEDSIGSLPEHSHRAGEAFDVIAVAGSMSSKDDAWLARKQLDRDAGWGWVCMQHCVVLEGSGWDREEVGKNHLVEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7H4</accession>
    <name>A0A9Q8P7H4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Multifunctional methyltransferase subunit trm112</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eRF1 methyltransferase subunit trm112</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04727</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRM112 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760475.1">
        <property type="nucleotide sequence ID" value="XM_047903875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7H4"/>
    <dbReference type="GeneID" id="71984605"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04727"/>
    <dbReference type="OMA" id="NMLTSKC"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000021">
        <property type="entry name" value="Multifunctional methyltransferase subunit trm112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14328" checksum="3ADF3D00392487D2" modified="2023-09-13" version="1">MKLLTLNFLTCARKTCKSSPAAFPLHPKEAELEQVEVDLNPLFITNMLPRLDWEAIKTLNQELGLPTLPAETPGAEELAAEDGEPTQMLKDLHTLLMETSIASGKLACGNCGHEYAVKEGIANFLLPSHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8A2</accession>
    <name>A0A9Q8P8A2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761269.1">
        <property type="nucleotide sequence ID" value="XM_047903951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8A2"/>
    <dbReference type="GeneID" id="71984681"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04803"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF24">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="247" mass="27363" checksum="A8DAE351B5A4ED84" modified="2023-09-13" version="1">MAPTLRSSQAKMPPTLILIRHAEAEHNATENWDLPDPRLTEAGIQQCEDLQRHLQSSCPLAQRVETIITSPMRRTCQTTLTALAWLVKSGIPVEVNAMWQENSTEPCDSGTAIPKVAKEFPELDFSTVDPTYPNKGPGTPYAFAESANAARGQACLRSLYDRPEKVIAVVSHAGFLRTAITKRRYANADYRIFTFKKSNGGALELVEDLSTMRKGGGLGRSPKGIFKVKEWDFPPEEAEAGEERDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8C4</accession>
    <name>A0A9Q8P8C4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761451.1">
        <property type="nucleotide sequence ID" value="XM_047903561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8C4"/>
    <dbReference type="GeneID" id="71984291"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04413"/>
    <dbReference type="OrthoDB" id="3634998at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040510845" evidence="1">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="19498" checksum="34A4917777BB580C" modified="2023-09-13" version="1">MLFTKLFAVTCLSLCPVSSFSLPQTNTPTCTAATRQTILEGIPNGFNAVAPGASAAFIASLPLIPSCSLTLFINGLPGLQVAPDASTTRNSALLVRQAFLRVTPSVPASVDSGNGTTRSELEIDTGLLHTIALPVTFHAGLVFNYLDNCTIESVVGILTVPTSVLGIPILMPDVVAAVQELASQAAAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8L0</accession>
    <name>A0A9Q8P8L0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761690.1">
        <property type="nucleotide sequence ID" value="XM_047905204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8L0"/>
    <dbReference type="GeneID" id="71985934"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06056"/>
    <dbReference type="OMA" id="RIFSIRM"/>
    <dbReference type="OrthoDB" id="660550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="23711" checksum="E5511D506B75B842" modified="2023-09-13" version="1">MAFTSIANSKSTPYFFNLINQGKVSPTEFSFYLGRAKSNTQGLSEMTLGGRDSSRYTGAFTNVPVTSQTYWQTAIDGASVGSKAVSGTSGRSAIDTGTTLALAPNAAAAAIFAQIPGSLPIPSLVVIATLYAYPCNTKANVSLKYAGKNFAINNIDLNFGKLSDQLGLPLLSGTNYCLAGLGGADINPGIPLWIVGDVFLKNWYSTYHYISPSSAYVAFAKAAGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P950</accession>
    <name>A0A9Q8P950_PASFU</name>
    <protein>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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            <begin position="102"/>
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    </evidence>
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</entry>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="16341" checksum="7BD428AEE5823EDA" modified="2023-09-13" version="1">MSRTLTSEITGPTTTSLPVPLGEVVDIWSWAKLQSNPDWYEKIVKPAVEQHRTKYYEKIAESAVARQAISSAAKAVTCTQLPGSGHKPSDYIWHSPYHASVRPSLDDGFSGGSNDDFDPDNGYDSDSSYERVCEENGADDIIKMLEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9N6</accession>
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            <authorList>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="UJO18136.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="33658" checksum="1A278C6CCB83E6F0" modified="2023-09-13" version="1">MARDIVKPHRTNHVRRARKIVTRSAAARAEGTGGNLPDAPHSEPDNMSTDSEGGVLLETATHSQALSDSKRGPRVVESSSDDMSKNEDLGNTRTIEGQRDYADKCSRWMGDQRRSENAAEAAQPAVPVDLEDERRTRYLDMIEASWGASWSGKFCKAQFLPQFENDAETSRHHLVRDMSLTLVKHFAVVSAWATLNETARLLKDRVVRRRRDQVARASGQPPHITPADIKGVLLEEVKLPEDGMTWDRLARDGLVERPSSGEDCWKYQRTSDQSEQHSRDRRRSLALSGSMARRVGSFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA03</accession>
    <name>A0A9Q8PA03_PASFU</name>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="N-alpha-Ac-DABA_deacetylase"/>
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    </dbReference>
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        <location>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA71</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763093.1">
        <property type="nucleotide sequence ID" value="XM_047906253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA71"/>
    <dbReference type="GeneID" id="71986983"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07105"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="18530" checksum="3195B8B225D5A4EF" modified="2023-09-13" version="1">MNPFFSMKKVQELEGRVKVHVEKLRDRFLEIKGTGEVMNVMAATSALTLDVISGYSFGKSCNTLDTPDMGLWICKMLEDGFRPERFLGERGKEVLRYMVPFERGPRNCLGVNLAWSEMYLAVAAVVGGVEGLELVGTGIRDVTVDREYFIGVFPKESKGVRVKVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAL8</accession>
    <name>A0A9Q8PAL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763331.1">
        <property type="nucleotide sequence ID" value="XM_047905795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAL8"/>
    <dbReference type="GeneID" id="71986525"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06647"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF11">
        <property type="entry name" value="AMIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="80"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="232"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="538" mass="59122" checksum="01CB3583B53B0092" modified="2023-09-13" version="1">MGSTTEQWKEIAKKAQQKVIDDIPLEWRVPTNRLPGHDVRDVTGFPAKSGLLSEQDLEITDSYATEIVAKLAKGVWKAEDVTRAFCKRAAIAHQLTNCLTVIMFDDAIKRAKELDAEFEKTGKPTGPLHGLPVSLKDNFNIPGYPSSVGFCSWAMDPMEQQSTIVGILKELGAVPYVKTNVPTAMMIAESVNNCYGRTSNPLNRENTSGGSSGGESALIALRGSPLGVGTDIGGSLRIPAACTGIYTIKPSFGRFPHFDARSGLAGQEAVASNHGPMARSIADLRLYTENVINSAPWLRDPKCIEIPWRPVSLPSKPKLAVLWSNDLVQPTPPVTRALRETVDKLKKQGYDIVDWPATDHVEAIDLLAKLFLADGGKSVEEILRSVGEPFRPEMKAYEEATELGVHELWQLQKQRTALAKRYLDRWNEIQPDAILGPVTPYAGAPRAGEFTHVGYTGVFNILDYTSVSFPSGVKVDKEKDGKGEEGFEALNEVDKTTREQYDPELCHGLPVSLQVTGRRLQEEKILALVHRIEEDLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBB8</accession>
    <name>A0A9Q8PBB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar protein sorting-associated protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06718</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763693.1">
        <property type="nucleotide sequence ID" value="XM_047905866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBB8"/>
    <dbReference type="GeneID" id="71986596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06718"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="9">
        <location>
            <begin position="20"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="626"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="10">
        <location>
            <begin position="862"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="817"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="969" mass="109148" checksum="25B01259454A64E5" modified="2023-09-13" version="1">MALDATSGYAAGAHDHVALPIFDVQKVQMRFDISADFVAAQVANNVLVLALSTGRILRFDLDNPEDIDDIDLPKRPAEIGVIRKLFLDPSASHLLISTTLGENYYLHTQSRQPKVLGRLKGVQVESVAWNASQPTASTREILVGSTDGNVYEAYIEPEHTYRSIEKYVRNVYNPPHGPIVGLYTDLVSTRPEVRRVLIATQHKLYHFVGRSAGRGNESSIYAKLLESEEPTVHEIDRTVNATYACLATSPDPPDAPPSVLDGQSAERAYAWLCAEGIYHGRLLTSSPDLATLGKQLFKESKMFQHSKLPPIQSTSGRHRAAQPPVAATILTQFHILALVDGRITGINRLDETVVYNQQILESGQPNLGLFADHQKNTYWLFTPQEIFEIVVTDEARHVWKIMLQQGQYEAAQQYAKTAEQKDAVASMTGDHLISQGKFTEAAIILGKSTKPFEDVALSFIDKGEHDALRRYLQVKLSTLKRSATMQRIMLASWMIELYMAKLNQLDDTISTRAELAADGTATSADTQKQLPVIRKEFQDFASKYKSDLDRKTTYEIISAHGREEELLYFANLVEDYNYVLSYWVNRERWQEAMTVLKKQSDPEMFCRYSTVMMAHLASELVDVLMRQTGLDVKKIIPALLNYNKILGDGTSINNNQAIRYLLFCINHSHSTEPAVHNTLISMYAAHSTKDESALLSYLQTQADNRHQFYDADFALRLCIGHRRVQSAVHVYTTMEQHAAAVDLALKYDEVELAAEVADRPGIQDPLRKKLWLKVAKKVIGQNKGIKAAIEFLKRCDLLRIEDLIPFFPDFIVIDDFKEEICAALEEYSRQIDALKREMDESASTAQHIKDDIKSLDQRYAIVEPGERCWKCRLPLLMRQFFVFPCQHAFHADCLGEMVMNMAGMGKGKRIRELQKEIGRGVALGKRREGMVKELDGLVAGACVLCSEMAVKQIDEPFITAADNKQEWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC51</accession>
    <name>A0A9Q8PC51_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764096.1">
        <property type="nucleotide sequence ID" value="XM_047909651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC51"/>
    <dbReference type="GeneID" id="71990381"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10503"/>
    <dbReference type="OMA" id="CCHVQLL"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF41">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G01330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="52"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="31753" checksum="421F7929C7F1DA93" modified="2023-09-13" version="1">MAPISTTDIPALDTVPKNGHKFQQKEGQEIGFVDTPKLQFKDKYEEREYIKGRLAGAYRIFGDYGLNEGLAGHITVRDPVDPATFWVNPLGIDFNLINKSDLLRVDHKGNILDHGRVKVLNRAAFLIHGAIHEARPDVLCAAHTHSVYGRAFCALGKPLDTISLESCFFFEDHVVFEGKGIVLDEDEGCDIAEALGNKKAALLRNHGLLTVGQSIEEAINWFYMLDKCCHVQLLADAAASGRGGETAKITREEAEYTRGVAGHPKAGWMGGNAMFELIDEKTGKSYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCD9</accession>
    <name>A0A9Q8PCD9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxidoreductase ptaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10478</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764231.1">
        <property type="nucleotide sequence ID" value="XM_047909626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCD9"/>
    <dbReference type="GeneID" id="71990356"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10478"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="92"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="178"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="344"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="513" mass="56583" checksum="098A7CCA9DE54693" modified="2023-09-13" version="1">MSLLLPVLEGLGNVTFINNLLSSVGVLVSLVPGLLQNRNSPLGILLTPVTPDTGVTRYYNFDVARGMLAPEGIPKPMLLIQVTVKSPITGPEEGTALHWHRLLQKKTTWYDGVPSVPMCPIAPGESFVYRFQADLYDSSWWHSHYSAQYAGGLFGPMIIHGPTDNYPSGIGEVVDLGPVIVSDSYFTDYYTLVEQSMSNNALVAALVTSGHTLIQGKGNVDCSTAPAGSNCTTNAGLAKFNFKPGRTHLLRIINTSAAGLMVVSLDNHKMTLFVGQRTDVLITADQRPNAYWLRVRQPTLCPYYPIKLAPPDVTLVIQITQAINATGHTHYEMNGQTFSANYNYPLLNCTFNGNTSYPDDPQWNVFNFGSNETVRIIWQNNVPFGHPMHIHGQNLYVVGEGVGAYNGVNAVRPSNPQRSDVHSLRPNGYLVTQLVSDNPGVWPFHCHIAWHVGQGLYINVMQKPEMIQQGPETPGIIAEACDAWWTYTENNIPDQIDPGLKKNRLKKDKFILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCN6</accession>
    <name>A0A9Q8PCN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Eukaryotic translation initiation factor 4 gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764480.1">
        <property type="nucleotide sequence ID" value="XM_047909643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990373"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10495"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000020">
        <property type="entry name" value="Eukaryotic translation initiation factor subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.30">
        <property type="entry name" value="eIF4G, eIF4E-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022745">
        <property type="entry name" value="eIF4G1_eIF4E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036211">
        <property type="entry name" value="eIF4G_eIF4E-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD38</accession>
    <name>A0A9Q8PD38_PASFU</name>
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        </submittedName>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_047909046.1"/>
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            <begin position="28"/>
            <end position="45"/>
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            <begin position="130"/>
            <end position="140"/>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="383" mass="42333" checksum="6E4460A0F18D965D" modified="2023-09-13" version="1">MLFLLNVTKVLPLRNISIQSEGKAVNKMGKRRASTGRQPPAKRTKPAPTPKTTKGKKSAQVETSSAPLDLQQYIGTFDDINYDQARRWCTYFGRKGRSGKLPELQDWLKEKYERHGKGPLDKPNDLPPSRSASPKSSQDSPGEKSPGSDRPGSREGATPDVEPDEAPKGVSAESSARPDASESVRDAWRLLRTAANILERDREHDGVEEALDQLKDVLYTTLANYMVIEVPKPPDESEAVPSAPSSRNLEAQGADLQRLFDLRAFPAEKGEGEGEDDDDIEYLVLKKASLDDDTDAIIARVREMETLEEFEHVGTYAKLVDLALIELRDDQPNDLDDGSGSTESIEGFADELSFTPPRAMYDPVSRSVPGTPGPRKIRRGTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDL5</accession>
    <name>A0A9Q8PDL5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11577</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDL5"/>
    <dbReference type="GeneID" id="71991455"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11577"/>
    <dbReference type="OMA" id="QTERWER"/>
    <dbReference type="OrthoDB" id="3643842at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="60"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="64"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="131"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="325"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="60779" checksum="92B39A85ED921804" modified="2023-09-13" version="1">MAQTTMQALKPSMDDGQAISTSSTHVAESTHTADYVSPAWGRRFNSDTHANSPWARKVILSLDGGGVRGYASLLILRELMRRLEVLERQESKDESQQSNSDYLWNSGSEDGHTQDGAREFRPHHYFDYCVGTSNGGLSAIMLGRLQMTVDKAIEQYDIVGTQVFGHPRKFALMGLGRTRYGADNMNAALQNAMLEGVAAEVERSEHRKTMYPRVGARILDRKRLTEDERIQIKQLKTSARQCRLRNENLDAARTIVVSHGGNMKREAYLFRSYDHPAPSASDGDRVLHLNHGPASEAAIWEAARATSAAPGYFFMLEIAEGRFEDGGLGENNPVSLAYEEVKQMHLRREPLLILSIGTGLEPDRTWEKDIPFRPLKQAVRMWRDLEQLQNQITDSEKTHQRFRGRVNDSNRKNKDPQSRERNHIHYHRFNVPDISNIRLDEWQPPATGQTTKQNMETAVAAYLAQDSTSRDLDACAQILFQTRCARAQTERWERFALHLTYCCREKDCEAVTFTSRKSLRKHAIDYHGFVWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC8</accession>
    <name>A0A9Q8PEC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC8"/>
    <dbReference type="GeneID" id="71991141"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11263"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="215" mass="24907" checksum="1A807E903FB5BC9E" modified="2023-09-13" version="1">MSEQPIDHRTMSPQNTLTCTTSLVATTTTPSQPTSCAFFDKLPAELRLDVYELTFAQHDDKEVELITSSPPSASLLLACRKTYHEARATYQQARRRYWKETKFSIQVTDPRLPLALHAALPRLKRQGLEHIRHLRIRFCHPTFAGIYDQYELVTVRGVWRRVVVRPGLWSSTCACIDRFRSLKIWDTEEEAHESLVRHGERLGIKAQILYVIERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEH7</accession>
    <name>A0A9Q8PEH7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar pre-ribosomal-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765340.1">
        <property type="nucleotide sequence ID" value="XM_047910510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEH7"/>
    <dbReference type="GeneID" id="71991240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11362"/>
    <dbReference type="OMA" id="RYITFKR"/>
    <dbReference type="OrthoDB" id="72892at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059018">
        <property type="entry name" value="HEAT_URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021714">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
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    </dbReference>
    <dbReference type="Pfam" id="PF26140">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11707">
        <property type="entry name" value="Npa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="100"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 central HEAT repeat" evidence="4">
        <location>
            <begin position="632"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 C-terminal" evidence="3">
        <location>
            <begin position="881"/>
            <end position="1081"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1117" mass="125862" checksum="80627A41EBF83060" modified="2023-09-13" version="1">MSKRERQQDEDDRPPKRPRPDHQPVQTQEVTFARQLQDFLVFRQDGIQQLRNGIASFKLFLESILYHKEEDNRGRQISILREYLEKQKPADATDLEHPFLSQLWQAWSFANQNNHDSLASSVSAALALLLKTLSGILDLREHGLLLCRTVLQNQHLRLVKRCLDAPKHKDFVISPSLRLLTEVVSFDGGVSARELYKRREQTFDTRTLRRLLSLVKLDFPEDEARRKPAVRTLALRYVLALFKYLHEGGKADVLKDKPLCGALFQHIQDDPAELVTDLLSTIEQNVLRDEAIPRSAKASLLTSRNLERITTIASQAPEEHQAADRAFDWLRSVCTTPKYGILRHSGWYPPGTTTSAVSKSSTSIDLGLDSLEFYDREEAINLRNTTLLSWTSTLHAHNNERERGLLLACFTAAPELVAPYFGEKTMQLDPKLSNTWVGYASLMFEVVALPVPEHLGAGDDWADLPPQTAIVLESLIPRPLTQKILVRCLNQNHDLVAFFATRILILALEKVQVVIKDIGRHPNGGHQNIWNEALERLVQRFAERCPSIKDVIAAFRQLADDDEHIMQREAITRLLGLYYQVLPQQALEEQFDVSVALTAALARSEAHDEVQSETSELRSVELINLLNIARLSTGMKWFNKQGGLAHTPIVTLLRIHARNTRDARVRELLQHILVENDVLNSFSDGGRASPLDALVASFTNFVENSTVWEFLDESLQRAVRKPVKYLDDLIALSPGKQDASVDGRPDTPSLLTAVILEQASFVVAKIDAEGESRIAWAELFLQLLRQTTDESKALDKLTKAVNKTPGWKPPKSKIDLTALLEKVVLGKDAADAEVEQLPADDSHVVPQLSFSTLPSEPTRHPELTRWNQKDLDMAIEDGDISALFLDLCSSESDIRRQALTQLIKLKLQLRSDSTYGNSAQLSLLVGEVAETFEQHYLPSNTALPYIAGTFAVRVLQVQIQPQHFMYPKVNRFLIRGPEWRVGKLPGYWLSTTTLSLPEEDDAYWKEVQWVLDWILDGLRTTADLDILRRGDVFEKVLALWHSPGAIPHKNVRERISELVNRAACLPGGSDVLVTRTGALSWLDIAAQLGETRSGSLRSLVKQTSSQERLSTWAAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEN1</accession>
    <name>A0A9Q8PEN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_10843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PEN1"/>
    <dbReference type="GeneID" id="71990721"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10843"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040205402" evidence="2">
        <location>
            <begin position="17"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="15196" checksum="A629CDACD6CB8A25" modified="2023-09-13" version="1">MHFITALSLFAAAVVASPVSHPAAPSHAAPSIPTHAPIPVPSHDTKKHHSWASYHHNNEERAVPSFAKPSFAVPSFPVPSFPIPSFSIPSFPIPTPSFPAIFPTTTITIPGGPTITLPPRFSETVITITKPITTEFTVPVPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFJ3</accession>
    <name>A0A9Q8PFJ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase I termination factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09478</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765924.1">
        <property type="nucleotide sequence ID" value="XM_047908626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFJ3"/>
    <dbReference type="GeneID" id="71989356"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09478"/>
    <dbReference type="OMA" id="IYEMDEG"/>
    <dbReference type="OrthoDB" id="39591at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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</entry>
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                <person name="Stergiopoulos I."/>
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            <dbReference type="EMBL" id="UJO21628.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG57</accession>
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21885.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="424" mass="46651" checksum="5FA020BAD5CE9DD8" modified="2023-09-13" version="1">MHTSLPPLSKGRIALYLFAGMSIFFITFAAVASWSQPAAGLFRPSSRYQDASGSISSLASLALEKVLGDGSPVFGLPTTTQASTATWMKAYHDDTKIVHMNIPGTHDAATWNFSKTTQEYLEPVTDLINITEVDSSFYRCQNQSMSTMLNAGIRAFDLRYAYDVTKSTLVFWHGNALQSQTATVDDVLYSFYDWLDGHPSEALFLSFQHEGGNDDLGTQLMFYNILTTPAAKKYILQTRGSLGTLGEARGKITLLRRFDLDLLPASYEEAMPGLHFSPKNWTDNGANITLVYNQTTGETAYIEDYYSPNTRKNSSAALNIQYKLNATEAALRRASISNADSLHWSFASSTNTGNDPPDTPQTQALGNGTLTPKGGVNQQLVPILKTLQGKRLGIVMFDFFEEPGDLIPLFLSLLSPELAKGYEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGG8</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="35464" checksum="DF50C948DDC94B97" modified="2023-09-13" version="1">MTNSGETGDDSPQSVNRVRNTIIYQLFELASQDETNPILLDTCNKIFDNPKKNKVSKVKQNNKRDDSMPELGEALSRLSAELKQEVIIVLDDIDRMSDEDQRTLFDELQDAIKRTKVDDPKQKPLRILAGASVFSVYRELASNDLSIDVGDYNQPDIEQKITAELGNLSGWNEAQVSEAKDAILRRAGPIFRYVDQVAVPFIREPFQGPLSERLDDLPHGMDETYVQAVRSLPPNYQALLRTALSWTLFTYGPVKALEIMEAFNGTYLGQLSEEDLSAVKEDDPKRSHASELQMQQLSTAGSSFLTFWNTTSTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHB7</accession>
    <name>A0A9Q8PHB7_PASFU</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_09780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHB7"/>
    <dbReference type="GeneID" id="71989658"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09780"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29276" checksum="17D438F03B18184C" modified="2023-09-13" version="1">MKADVSAAFAGSHLGRHNDVDQDSTAFLHDTEDLSVGMSATTFQESKRKEERKAERTIRKLEIMLSEVTLGGAEHGVDVRDFAVVGKPHTHLTITGALHYTHTGASTLASYLDIFPPTLLEASPVVLNVYVDNAMRYGHTSLDFTKLNHFLASFATCLDRRGSSHTSFQTLQLHFFTHRVGASDPIFHDILYPIAKIPTGTTLVLKGLEAKLQGRLLELRSGDVAGRDTLGGWLRLRSELMANGETGWKAKFGVASVDLMVGGGGGRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIA7</accession>
    <name>A0A9Q8PIA7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12086</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71991964"/>
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    <dbReference type="OrthoDB" id="4094614at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040175885" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="5">
        <location>
            <begin position="39"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="29488" checksum="2AC72C77CB7AB039" modified="2023-09-13" version="1">MSDFSYFALFTAGLAAFAPLASAYTKPVGPEPLGNPFSQPGLNTVVPAGGNFTITWEPTTKGTVTLLLLKGPSTNAVPQYPIVEKTENDGTYVWQVKDDLEPSAEGVAQGYGIQLIDDATGQYQYTTQFGISNDDYKKSPESSSESAKPTKSAEGYGKESKTASSTYHKHFTTYCPEPTVISMGNQSYTVTAATTLTITDCNCEVHPTTSAHMPVGTGNAYPSHNVTMVAPTGYVPTMATTASTYNMPSASATTPPQQTGAASTVAGGVFGAVLAAGVAVLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIG6</accession>
    <name>A0A9Q8PIG6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_12368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767398.1">
        <property type="nucleotide sequence ID" value="XM_047911516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIG6"/>
    <dbReference type="GeneID" id="71992246"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12368"/>
    <dbReference type="OrthoDB" id="3641440at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38976" checksum="01814E6977B36D73" modified="2023-09-13" version="1">MAPRHLVAGKTFAEASRLLDEGVVEYLCSVIQMSVGRIFTLDINVAEMLEHATPETVPSLQCLFEEILLNPDYTKMWWNPQKDIEVMDNTIAHFFQGTARPPYTHSTYYGDRTCHIKPRFHIKSPFFNGTRPRHLCFPTLPREDQNCDLHVPGNNDKGMSCPCSLGCIDIAAFMGHLCRLQGLPVEKLPWTQCRHGIGYEKFLSDMLKHDRIGPLVHKLRGTKSLEHYQRLGRRGLEQDTEVQGYSTIDVVGIAAVIDNIITSDDAQFVAGLLAEYCYMQKSHTPGFSVPRKIAQRQSLLGPCGIISTFEDNPRLYVRKAFKESTISQLPSMLTSDWSVCLSQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ55</accession>
    <name>A0A9Q8PJ55_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidate phosphatase APP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767975.1">
        <property type="nucleotide sequence ID" value="XM_047912186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ55"/>
    <dbReference type="GeneID" id="71992916"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13038"/>
    <dbReference type="OMA" id="RDSSWKT"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF1">
        <property type="entry name" value="FILAMENT ORGANIZATION PROTEIN APP1-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="236"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="441" mass="49357" checksum="0B4549C38CD80C92" modified="2023-09-13" version="1">MDFLKEVADVGRRGVVDALQSAAINRDAPLSPEVPDALRAFMPDLFDRFPIVFPWTRPEAIDPALHTVWLLDNTAFRTPQPGDRRPDLGELISSRHAKPERVGEDGKPHSVRGGSGWEVEFVACYFVKNSGRDLSKVVGGIAHELQISDDDIATKKRISERVQPFVDTILPKRTVRIAIDGKELQTLGPSGYSGISSNLHQLHFQPPTQPFQSSVVNLPPPFGLPATTIAAEERGWGIISDVDDTIKITQTPSPLGILHSTFVVEDPNPVPGMPALYAHIQSTLQTPPFFYLSASPYNLYPFLRQFREAHYPQGTIILRDASWQNLGGLIASLTQGTEQYKVDRIKKIHSWFPHRRFVCIGDSTQADPESYGEIARKFPGWVKAIYIRKVTGIAEMDEQKKNSDERFEEAFKGLDRSLWHVFTEPAELAERIDMLATQSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK32</accession>
    <name>A0A9Q8PK32_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase aba1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768236.1">
        <property type="nucleotide sequence ID" value="XM_047912330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK32"/>
    <dbReference type="GeneID" id="71993060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13182"/>
    <dbReference type="OMA" id="NPYHETM"/>
    <dbReference type="OrthoDB" id="3644013at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF77">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="392" mass="43563" checksum="A25CC4C87908BDEB" modified="2023-09-13" version="1">MTSFLQATSWPALAALAAGAFILYHIATAISTWRRLASIPAPSWTAHISNLWVAAVTYSGRQYSVHRDLHRKYGPLVRVGPNSVVTNDPNVIRRITGVKEGWHRDSYYKAGKFNPYHDNLFSRLSPKEHTWAKSRTIAAYSGRETPDLEIGVNELVETLLERIENGYANHVDSLPTLPLMNLGKISNYFTIDVITRLAFGEAFGYLSEEKDHFNFLAGLHDLWPQMSSCADLPILRKILFSPTFLALLGPKPTDKMGFGALMKPANDHVAKRFAHDAKAKQDMLGSMIKHGLNQIECETEGLFMIIAGTESTAAAIRSAIIHTISSPRVYSKLKQEITTAVREGQVSDAITFQEAKALPYLQAVIYESVRMRPPLIGFFPKVVPPEGETILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKC8</accession>
    <name>A0A9Q8PKC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768397.1">
        <property type="nucleotide sequence ID" value="XM_047912424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKC8"/>
    <dbReference type="GeneID" id="71993154"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13276"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="357" mass="39101" checksum="BA3ED349378377F1" modified="2023-09-13" version="1">MASRWPEILLLCLIAAASGNWILFLTTGGLQELSEEDIKSYIAEDLRAATHFTSIPWLDAMLKQNTLVNVVLLTASSPISAQTRPMMAFLLEDMTVAIAVLVRSLQRRELTSAMRLALLLFWLALTANLTSAFVLPLYSLVHLRSLTGDNTSRITARRLDGVTSTFGALIGFGLPAFMSLDPLQHGAYSQLRWIAVSTAFPMCVTVVECFRHAMYYAIPANGHVTLPKGIRVADARNAFLLLGSGAATAHVLTRRRFSLGIGEVLVPTQRLDMAAHEKFGKLMAFMQADCILTNAWMILLAIIVSTGQYHKKWYMNCLSIGVSTWAIGPGATFAFVWALREGDSEGISTSVTKSTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL20</accession>
    <name>A0A9Q8PL20_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-rhamnose-1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768715.1">
        <property type="nucleotide sequence ID" value="XM_047912633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL20"/>
    <dbReference type="GeneID" id="71993363"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13485"/>
    <dbReference type="OMA" id="LTTHIAC"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019301">
        <property type="term" value="P:rhamnose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000417">
        <property type="entry name" value="Glucose 1-dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0684">Rhamnose metabolism</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="26447" checksum="A0845BBA921DB744" modified="2023-09-13" version="1">MAGLLAGEVAAVTGGVTGIGRAIALGFLREGASVTVNYLDSEESVKHFESLKAEAPKDARLTGVAGDIGKKEVAQAIVEKAVSSFGGLDVFVANAGVSQFKDFLTLEEAVLDSHLDTNIKGTFWTSQAAAKHMVSQGRGGSIIGISSISAHLGGAQQVHYTPTKAVVLSMMQSQACALGKHGIRCNALLPGTTRTALAAGDLANADKLRYLETRTPLGRVADPEDIAGPAIFLASDLSKFVSGAQILVDGGISVSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL58</accession>
    <name>A0A9Q8PL58_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STF2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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            <authorList>
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                <person name="Samaras A."/>
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            <authorList>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLW9</accession>
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLW9"/>
    <dbReference type="OrthoDB" id="6430009at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="91" mass="10924" checksum="E6DA3CA1819A9020" modified="2023-09-13" version="1">MYTYRPRAKCFYIIPTRHQFLNKQFNHNPKEKLPPIYYDITDAFLAKDHKGLLPYRLGVDYKIHIKPNSLQEPLYRKPYGLAKKENEAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ83</accession>
    <name>A0A9Q8UQ83_PASFU</name>
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        <submittedName>
            <fullName evidence="13">Mitochondrial inner membrane protein OXA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07532</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO18684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987410"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <end position="501"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
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        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="501" mass="54478" checksum="867854F4FAA0AE52" modified="2023-09-13" version="1">MPSRGLRLVRGNAPSLIRQQCRNLSYTPRPLLRNTSPRIGSLAQTPQPWTRSTPTAIISIPAIRHASTTQTPVDPATAPLPENSTSSFPDLDTITLNTVPKTAEGIDISSIPEGIGYLKQIGLEYGYGPTSMIEWVLEHMHIWGGLPWWGAIAATAVAIRVVTFPLYLKSSDIMARQNALTSVTKPITDRMTKAQKEGNTAEVMQAYRQLGQIRKRAGISITQQFLPIILQGVIGYCGFKIMRAASELPVPGFKDGGFLWLQDLTITDGYLLMPIIMAGTVHMIVRLGGETGAQTQLPEGMKKVMLYGMPAIICLVTAWQPGAVCVWFAASGALGIVQGRVLQNAAVRDLFGLAPIYVPKPGEGGGGFLSAMLEDRVKGLQPTRYEPAPSAGANGGRNAAYMAPNYQSPNIHRQGKTIDTTLVAPNPAGTSAPSEEMIQPGMPATPKKGMFDGLKDQLQGKISEARQVRAKTPEQRKKEEREAFKRRAKQYEERAQGRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQG9</accession>
    <name>A0A9Q8UQG9_PASFU</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO18758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="423" mass="49433" checksum="DC4EA200BF937A62" modified="2023-09-13" version="1">MKLTNRSAPSDRRGKLHTKEMEWCVLKHYRTHTMYILDDQQGDAPVADLDLAAHYARCADFAEFFQIYSVYEVRSISFPPDSTQEQFTEFIDEILGNKGSDDHVIFVYFGKAYGEDENYMWQFRGAPDHPINAHDFIHQVNHTDIDVLFILDCFIQTRPTKPWSRDHAMTEIFAMNTGMHNEDGERIRHRGDYAVSIIEYVGKYFNRLQERGPPKKDRAMRSIPEILMKDKEMYDNTIRLWFAHPKPSNTPSEDDPIWRFKCDPVKISRDTGYHTNEYIQHDKAYDTTIATMPVKGQLSKMPRKASAYILDACPEDEDDGFKVMSIHYQKQRIMRLLHERHIDCEVCAVSFAPNAQAGDVLKYFTQQFATKTRNELTILYYHGNAGSNGKSYTWRFEKYPDQDINAYELILFFVNSGLDVFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URC3</accession>
    <name>A0A9Q8URC3_PASFU</name>
    <protein>
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    </protein>
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    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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            <taxon>Mycosphaerellaceae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="6730379at2759"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
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        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="20848" checksum="85D747D89C7F0C6F" modified="2023-09-13" version="1">MATTNSILALIGYYLPGGILIGWTTISGLQASNVAGSTKKITVACVGPIVYTIGNIISSQTFQAKDAPKYLPAKISIVILYLLIMIDFLVMRWVFVQRSKLRDQARSELGEACKVGENHESLDQTDLENRELRYALWHAISSTDPRVLLVRVLLYCINILSASGPIDDATTGCKLKAKRLRRWYVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URD5</accession>
    <name>A0A9Q8URD5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase</fullName>
        </submittedName>
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    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10654</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764009.1">
        <property type="nucleotide sequence ID" value="XM_047909802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URD5"/>
    <dbReference type="GeneID" id="71990532"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10654"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000222">
        <property type="entry name" value="Serine/threonine-protein kinase psk1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="220"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="485"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="571" mass="63200" checksum="55C786A00C2A6F7A" modified="2023-09-13" version="1">MMPGMDIEISSGHALEIQQSPPTRISSPRPREVPAEADRMPIPKLDHEALREKAKKRRKNKKKGMQPAAPAVNVIKGFQTPVTSGGEESDASTNGTPRFGAARMQDFSSVASSPALRPATPGNISALKARLDALDLDEHAKMPSLARVMSSKSDCDSGLATPSSRGSDGDKTEMEAYDVPLDQDFISPEAGSVTPLYASQAIEGGLRTASIHRKMQADDFKPLRCLGKGAFGTVHLVRQQASGRLYAQKQFKKASLTVHKRLIEQTRTERTILESVNRHPFVVKLFYAFQDQEKLYLILEYAQGGELFTHLAMERMFSEDVAAFYLAEMVLALEHLHHNVRVIYRDLKPENCLLDAEGHLLLTDFGLSKVALDDDEDGSRANSFLGTIEYMAPEVIEGKGYDFSVDWWGLGAIACDLLTGKPPFGGGNHTKIQQNILKQKLQLPYFIGPDAKDFLTRLLRKEPHKRLGGASSKDVKALKAHRFFRKIDWKKLERREVEPPIQPVVTDPELAENFSSDFTDLPLSPVVTRGSKPFDDDGDDPYVAAESNPFGGFSFVASKSLLDDDQFMLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URE2</accession>
    <name>A0A9Q8URE2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Homoserine dehydrogenase</fullName>
            <shortName evidence="14">HDH</shortName>
            <ecNumber evidence="5 14">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_10507</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of L-aspartate-beta-semialdehyde (L-Asa) to L-homoserine (L-Hse), the third step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine; production of homoserine leads to a branch-point in the pathway as it can either be O-phosphorylated for processing to threonine, or O-acylated for processing to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:15763"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 14"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763983.1">
        <property type="nucleotide sequence ID" value="XM_047909655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URE2"/>
    <dbReference type="GeneID" id="71990385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10507"/>
    <dbReference type="OMA" id="IYTRCYS"/>
    <dbReference type="OrthoDB" id="67851at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000006">
        <property type="entry name" value="Bifunctional aspartokinase/homoserine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_Aspkin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070:SF5">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Aspartate/homoserine dehydrogenase NAD-binding" evidence="18">
        <location>
            <begin position="12"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="17">
        <location>
            <begin position="163"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>L-homoserine</name>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO19617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="39769" checksum="3408B3E95BD2C5F3" modified="2023-09-13" version="1">MSAKQVFVAVIGLGGVGKAFLSQLSFLQQRLSKQNPPIDLRLVLARRSTKQLFSSNFEPLNVQTVAQDLDKNGSPPPPFNETFGQLARAPGKVVLVDNTSDQGLASLYPMVLQRGISIVTPNKKAFSDKYDLWHSIFSSAANGTGSPSNGYIFHESTVGAGLPVISSLKELVETGDEVAKIEGVFSGTMSFLFNSFQPVGGGGGTFAAEVKKAKGLGYTEPDARDDLNGLDVARKLTILARIAGLPVESPTSFPVQSLIPKDLESAQSGDDFLEKLPQFDSEMEKIKDEASKEGKVVRFVGSIDVASKQVKVGLEKFDVSHPIAALKGSDNIISFYTKRYGSNPLIIQGAGAGGDVTAMGVTGDLLKVVRMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URP5</accession>
    <name>A0A9Q8URP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764324.1">
        <property type="nucleotide sequence ID" value="XM_047908995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URP5"/>
    <dbReference type="GeneID" id="71989725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09847"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040161400" evidence="1">
        <location>
            <begin position="19"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="154" mass="17246" checksum="8FDAF665CF14C9EB" modified="2023-09-13" version="1">MHTTHLTLLPLLTPLATSSLIRRQYVDPEIPIPGQQSCVRQWYGLGLDHWETDEKLCFTTWVGAIYDNARGCPDIFNALSDDYGADMLDWKCEAGNVQTLSGPGNEDFTKLHFCALVHRDDFLDADITARVCAVVDGALERMYAGIINEFNCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US24</accession>
    <name>A0A9Q8US24_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromatin structure-remodeling complex subunit rsc7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764687.1">
        <property type="nucleotide sequence ID" value="XM_047909616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US24"/>
    <dbReference type="GeneID" id="71990346"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10468"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF3">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="546" mass="60786" checksum="75A9B1D89DC75B61" modified="2023-09-13" version="1">MPFKKGHKLNLGRSRRTTLNVTRTPTPRVYDDEDDEEMADVDDTRDATELEHDEDVEDAATPAGDDGEEDDDEPRITSMPRRRAGGGKARGRQSRGRDLDGTPEPGMDDESENGTPLRRRRGRPGAERGSARGRGGFRGRRKGQAPDAPTHVTDKDGSVYEVQNDEALVDQDDEGDEKVDESGILKGGREYRVRTFTIMGKGERLYMLSTEPARCCGFRDSYLFFTKHPKLYKVLVGEEEKKDLIERGILPNSYKGRNIGVVAARSVFREFGAKIIVGGRKVIDDYRVADARANGEVEGELVDPDDHVPDDRSQYNRNRYVAWFGASEVYRQQGVSTVPGAKPQIRKHRNNITVQNWQFMHAREASRFNTAATQLRKANLEGVYDNNTNMMFYPKIMQPTHAKWEHIPAGTQQSDSKQLTNGHLPNGSSSDHDSVMSTEGQQSDTIFSDVPSLISRTFTVIDTTYSAPPISSVGYPGPDGHVEDPTSGPNGLSTVPQDLIDELPAECRVAFEEAKATELGWKQRWGTEAHSGQRGQLKIGFLGYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE2</accession>
    <name>A0A9Q8USE2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765074.1">
        <property type="nucleotide sequence ID" value="XM_047910755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USE2"/>
    <dbReference type="GeneID" id="71991485"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11607"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="34903" checksum="7E273F083D3AE10D" modified="2023-09-13" version="1">MLEQCMRFYSKMPRFINEVAAPQGRHRHFICCDDTAGYMDVLPQELWDMIYHKVFTAKPGLRYLDQYAQTHGLEPAHAARRPYCPSPDGFHLLRVDRESSEEYALSFFGGAGTIFIADNLQGSATDICVSWYRSLLRDPNHRELVLDVRALTVRNRGRMPSASERNESALRGRLRELGMDRIIHVGDEEGELTGGLADYATRSPSYVRHAPPPSPPPPPAPPALPPPAPGSDSGWEPSPPDHSKFMEEAQMNYAKDQSLKEARAAGIVVDNDDDFMHGNEFRPENLAEDNDDQSDEDEDDTGEADPDEEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT02</accession>
    <name>A0A9Q8UT02_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765646.1">
        <property type="nucleotide sequence ID" value="XM_047910073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT02"/>
    <dbReference type="GeneID" id="71990803"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10925"/>
    <dbReference type="OrthoDB" id="3643320at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="796" mass="88800" checksum="D783BAFE7C4A688E" modified="2023-09-13" version="1">MSSYNKHSHFSGYDDTPCTCPPCTAIVEKDDSLESRSRLRDDDFYTANPAGKVCLPSQTQRYYLRKAYSLAQGALWHALRDHWPRAQRQYYLEEPDQVRFGNSELEHCFGNSYCPSQQNGMCGLPPAITLATIYSVIDLRNAVCHPTPGGTQHIDRLMQRAQDLTVTLLDETRAMRVRRLRDDIQKDATRGLDDIAALEPLSWLPDTTSWALHHQIYFQQILTDLKRGDNSFGPSSVKHDPAAVRAARSWGMRCSSPREDDSRYVAVMAKKAAYVREACEGRRASVCAMLGAREQADDVVPAKRPLMCWLTQALRHYFNPSGLVTGTELLKMRLDTLSATSLLLGIGLAAPPSGNTGGSSNTPGGNLPLRPAAGSSKAASNAKQIKLGDIFDVLVDNSRDSCAKYYDPKAEPGKSEKHLNQYWDQVYTFTTSAEAAVEDKYTSNAEKRKLMQLYFGIEMSEKGVATKGIESLAFGKVQGDKKPRLACGSSFQIFQESNDPMKDENGEDTKPNIYRFMQDQGLQWHDYWVHWDKLDKSYNVMPRREDEKEAWGGDPDAVPYPPDPDDETLFHICNHPEVSAQTLGAGDPLPTSASEWQKRTHRKRGLVILCPETFQAMPDAVPPITKQKLDTGAHAVGTELATMGTNALALYHELFHLVMEGQVISDKARLTEDFPPYGADVDQNMRLPKGFPAKKDTFISQPGSALGPIQCGYIALFDKAEPRAAKLEDYFSTMSPEHYARFGLTSAMHDHDKMDWSSGVTQKAGGPFKGVFTSRDDYRKDIYVPINTCQPQDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTJ6</accession>
    <name>A0A9Q8UTJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">DNA mismatch repair protein msh-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09392</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of msh2 and msh6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766244.1">
        <property type="nucleotide sequence ID" value="XM_047908540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTJ6"/>
    <dbReference type="GeneID" id="71989270"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09392"/>
    <dbReference type="OMA" id="LVRFPQK"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000523">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000015">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000017">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="12">
        <location>
            <begin position="727"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="843"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="923" mass="103855" checksum="C0237317F353B775" modified="2023-09-13" version="1">MASRPELKVEDEAGFVKTFHQLEIGKPTDTIRIFDRGDFLSAHGDDAEYIARIQYKTTSVLKTLGKNLQSVTMTVTVFRTFLREAIFRLGKRIEVLATTGRNQWKVIKQASPGNLQDIEDDLGGHVESAPIILAVKVSAKANEARNVGVCFADASVRELGVSEFVDNDIYSNFESLIIQLGVKECLVQVDITKKDAELHKLRTIADNCNCAVSERPAGDFGKQDIEQDLTRLLRDEKASGTLPQTDLKLAMGSAAALIKYLGIMSDPSKFGQFQLYQHDLSQYMKLDSSALKALNLMPGPRDGAKTMNLYGLLNSCKTPVGSRLLAQWLKQPLMSQVEIERRQQLVEAFVNDTELRQTLQEEHLRSIPDLYRLAKKFQRKKATLEDVVRAYQVAIRLPDFIGTFEGVMDETYKDALDQEYTNKLQEFSNSLGKLQEMVETTVDLDAMDNHEFIIKSEFDDTLRVIRKKLDKLRYEIDREHQDAGADLNQDTEKKLLLEHHKVHGWCLRLTRNEAAVIRNKKKYQEISTQKNGVYFTTTKLTEMRREFDQLSENYNRTQNGLVNEVVNVAASYCPVIEKLAGVLAHLDVIVSFAHVSVHAPTAYVRPKIHPRGTGSTILKEARHPCMEMQDDVQFITNDVSLVREESEFLIITGPNMGGKSTYIRQIGVIALMAQIGCFVPCSEAELTLFDCILARVGASDSQLKGVSTFMAEMLETSNILKTATKESLVIIDELGRGTSTYDGFGLAYAISEHIIKEIGCYSMFATHFHELTSLVDTYPQVQNLHVVAHIGDGEDAVMNGDSTNSRRREVTLLYKVVPGISDQSFGIHVAELVRFPQKVVNMAKRKADELEDFSGKREELKAQASKDEVEQGSMMLKEVLRKWKDQVEAENLGKEEQIQRMKDLVQGNEALLANPFFQSVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTS2</accession>
    <name>A0A9Q8UTS2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription factor TFIIIC triple barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766484.1">
        <property type="nucleotide sequence ID" value="XM_047908659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTS2"/>
    <dbReference type="GeneID" id="71989389"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09511"/>
    <dbReference type="OMA" id="TTHVPNA"/>
    <dbReference type="OrthoDB" id="1877767at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019481">
        <property type="entry name" value="TFIIIC_triple_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10419">
        <property type="entry name" value="TFIIIC_sub6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor TFIIIC triple barrel" evidence="2">
        <location>
            <begin position="40"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="424" mass="45986" checksum="DE9941385AB1ABBA" modified="2023-09-13" version="1">MGQPMAQDPAAYVSNVGNHGNSVDVDEDGDDWEYEYDGHETEDFYFTLDLTTHVPNALVQAEASLQGRHKTPVNSSARHSTAVDAPNGQNADSSDEEDEPSAGQLQIVDLYTTRPLVKLDENVYTCSWQTDLGTQFHVAKAGDVNDKVRRAGTVLDIISTSQTRLIGIPVTLQPRNDTRRSRTPGASANHALSIDGSDIDADETSERFTPAPGSVAEPGKPLQIDRTLVKHQAGSDQASFLERLSQIKLKKGETDQVPIFSVKQYHHVDPAKQAELKQAARALDAQRRAKAKAEEVVATGQRPRKRRRKLTHAERGIDRGSNAAGAGRPGRDAVTQRLGFSDEAPPADRNGRWARQQQPAEAGPSTMSDAPDAENENGEPITTAEQTPGTATPVTLDATEQDALPPQEGNNTIEQPELMQKEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUM4</accession>
    <name>A0A9Q8UUM4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767447.1">
        <property type="nucleotide sequence ID" value="XM_047910870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUM4"/>
    <dbReference type="GeneID" id="71991600"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11722"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
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            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
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        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="30804" checksum="5EC3BC0BD2C72241" modified="2023-09-13" version="1">MQSFPNLQKTSLQHFRLTHTPILTSSSQDNMAGANDAAKRKRDDTGHREHRDRLTKLARMTVQDALKVTVGSADPENEKTFLVNKDMICAQSPYFKKACDAAQKVESELIFQLPDHKAAHFETYIDWVYTKPAQATPNFILRSSIGNPWGVGGLVKLWVLTNHMEDVEFKNLTMRLLVNMPLENKIWLARSPRMLQQIVANTETSSPLRLWLLDDVEARYSLEANTGLDQFVQHWPQVMVSELLKRFAARARAGATGGPPAPTDPTKYFEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXN0</accession>
    <name>A0A1P8YXN0_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Ecp48</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp48</name>
        <name evidence="3" type="ORF">CLAFUR5_14676</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943098">
        <property type="protein sequence ID" value="AQA29269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="UJO22663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573449" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="78" mass="8279" checksum="7D3247C547DC7CDF" modified="2017-04-12" version="1">MKSSILISMAMALLPLSMAMPTTTLPTTPLNPLLDPRQASCTDLTCRRDTDCYGNRCGDCDLNIGKCTCPPEANGGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YY91</accession>
    <name>A0A1P8YY91_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_02225</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
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        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_02225"/>
    <dbReference type="OMA" id="GVNDYSW"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:side of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="1,3-beta-glucanosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF5">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS5"/>
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    </dbReference>
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        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
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            <end position="362"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="396"/>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023288"/>
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        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQA29355.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO12414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="455" mass="47997" checksum="5A6C846D8D103025" modified="2017-04-12" version="1">MKGAIALNVASAALTHAVATPAKAAASSSSSGSLPAVTVKGNAFFAGEDRFYIRGIDYQPGGSSKATDSIADVDVCKRDIEQFKKLGINTIRVYTVDNTANHDECMAALADAGIYLALDVNTPKYSINRADPAASYNDVYLQSIFATIDAFAKYDNTLLFFSGNEVINADNNTNCAPYIKAVTRDMKQYIGSMGYRSIPVGYSAADVESNRFEMAEYMNCGTDDQRSDFYAFNDYSWCDPSSYQTSGWDQKVKQYGDYSIPLFLSEYGCVTNKRNFGEVAALYGTDMTPVYSGGLVYEYSEEGSGYGLVTISGNTITPKSDFTALMSALSKTPPPQGDGGYKSDGTPSQCPTESSTWEVKDFTGQDLPAIPEGAEKYMKNGAGKGPGLSGTGSQNAGGESTGTAAPGSGSVSAVASGHASSSSAANAIAMGEIGYAPFVCSGFVMLFTLFGMALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L637</accession>
    <name>A0A9Q8L637_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L637"/>
    <dbReference type="GeneID" id="71979924"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00046"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="430"/>
        </location>
    </feature>
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        <location>
            <begin position="431"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="65327" checksum="661CEB211EC0A02D" modified="2023-09-13" version="1">MSRWPIVLLQRLLDIFGLILVGLVILSFPITHLLHVIGFLFGSFFLDLWREHTHEPSNCWNKMVVIPPDPTIPPPLPPPQPPQKPRPLRTREDGAYHLDERKRQTQEDERRVLQDIADAEEKAWKAWWKKNKGGMWSADGKKKARARKVFAAAMEALRQEKPFDWDAKINQLHTVKTPVVQTPTPTVQTPITTTQKQSFGPAAVGQVQVSVKRLQHYPSHWMFSETSDRQTLYRDATLAPGYLSSRQLGELLSGPQKQISVFNPLLNEPSASFSCSKSSAAHQKMVQEYGDFIWQHAQSGQSSSARQRGRELPPMVKQSTTTFSTSHESKAHLKVVARYGNFLRAPSQQPQGSGQQDSSNGSSTDSGGDGSGASQNGPTGNAGKSLFDRITAPDPPKQTFASEGWTKENWANVNFNFGASSGAGTQPSGSTAGMGSPPATAGASGAQWTAASKNPILMEPTLEKQRTFVSKWINGLRTNIATGKVPGSVDTMSPSELTAYLATATEQLTHILGWCAPEGKWRTARVSYIQAKGTVGLSSDELDSVNSKLNDMSADDKASDKDLDPCIIAMEALISAMDKMGLWTPGQQRSSGVQRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6G3</accession>
    <name>A0A9Q8L6G3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756103.1">
        <property type="nucleotide sequence ID" value="XM_047900125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6G3"/>
    <dbReference type="GeneID" id="71980855"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00977"/>
    <dbReference type="OMA" id="DKEWEED"/>
    <dbReference type="OrthoDB" id="3649449at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="48115" checksum="55663FCAD2D308B5" modified="2023-09-13" version="1">MPAEAYDYDDPPPRSHGRRHRDRRPPPPDDYDDDEPYYRPSTKSRDPRYDEPKLSGTGSRRHYDASDDEDDPRSRKHDKKGAAEPDIPPPPIGDDRKSSSRKKPLNDDAPPPGAIPVPGTEADTKPYSDEEAPAPRRSHKESRSPRTHRERDRSYEEDPAPRRPHKESRSPRDHRERDRSYGAPATMPEPKKPSEDDRRRRPSKQDDSRRRRPAYPEDDSEPEYEKPKRREKPSRYPDEEPPRRSKPVRDPYQDERRRKPSRQDDTHRRRPAYPEDDSEPEYEKPRRREKPSLYDDGYGTDRPRRQPRDDYDRGYRTDGRDSKRDRYRDDDRRGPPRRDDRYRDDYDDYDRGHRGNRRDRKSNGNKLDIDGMMAKGQENWKKVAPVAKPLLSQLAKTYLQNGAGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L763</accession>
    <name>A0A9Q8L763_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_01154</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756491.1">
        <property type="nucleotide sequence ID" value="XM_047900302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L763"/>
    <dbReference type="GeneID" id="71981032"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01154"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="64"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO12125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="17905" checksum="EBEB9830DB3BB283" modified="2023-09-13" version="1">MSDDFKPGHARHDTALIHGLSSTEVQKLSETCIEAKARAYCPYSHFRVGCSLLLTNGVVVQGANVENAAYPVGTCAERVTIATAVCQGAKKGDIRAIAVATDISPPASPCGMCRQFIREFCEQHTPILMYDKDGKSVVMTLEQLLPMSFGPEKLLSTEELSNGVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7F5</accession>
    <name>A0A9Q8L7F5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L6-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756480.1">
        <property type="nucleotide sequence ID" value="XM_047899961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7F5"/>
    <dbReference type="GeneID" id="71980691"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00813"/>
    <dbReference type="OMA" id="KWYNADD"/>
    <dbReference type="OrthoDB" id="2436667at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000014">
        <property type="entry name" value="60S ribosomal protein L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="22807" checksum="33650C4D3A478035" modified="2023-09-13" version="1">MSSEQPQTKKFQKGERVITPAAQKASKYYPAEDVSAPKTTRKALRPYKPRQSLKPGTVLILLAGRFRGKRVVLLNVLEQGTLLVTGPFKVNGVPLRRVNARYVIATKTTVPLDGLDASTVKKASDEKYFARDKKADKKGSEEAFFKQASGEKPEKKQTSTERAEDQKKIDKALLSVIKKEPLLQGYLSTNFSLRKGDKPHEMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7L7</accession>
    <name>A0A9Q8L7L7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756648.1">
        <property type="nucleotide sequence ID" value="XM_047901129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7L7"/>
    <dbReference type="GeneID" id="71981859"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01981"/>
    <dbReference type="OMA" id="RTQGFNH"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="229"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="497"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="591" mass="66192" checksum="D698FB148E4FE7D8" modified="2023-09-13" version="1">MGTGKKEATRKVRQGKTSDGMANVKTKGENFYRDAKKVKTLNMFRDGKAQRNAQGDITKAAVFQSRAKPSARVEPNRKWFTNTRVISQDALESFRGAVEAQSKDPYSYLLKQNKLPMSLIHDNKDKERKDGLIQHKAKIRIETEKFGDTFGPKAQRKRPRLDVSSIANMAERSTTDYSKFEERQAEARYLAGLGEGEPNESVDASILADGQIATAREPVFSKGQSKRIWNELYKVIDSSDVVIHVLDARDPDGTRCRSVEKYIKEEAPHKHLLFLLNKCDLVPTSVAARWVKHLSKDYPTLAFHASMTNSFGKGTLISLLRQFSSLHSNRKQISVGFIGYPNTGKSSIINTLRKKKVCTVAPIPGETKVWQYITLMKRIYLIDCPGIVPPSMTDSPEDILLRGVVRVENVENPAQYIPAILAKCKQHHLERTYEMKGWSMDDDTAFADKPEKQRTEEGIKFLEVLARKGGRLLKGGEADMDGVAKMVLNDFLRGKIPWFSPPPATVGEDEKPVESRDEALGFTHKKRKRELGDSGSQAADEEQDEEDDDDEDGKDDEGFEGFDENDDNASDDAKSGGVEIDPGESDDETPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Q5</accession>
    <name>A0A9Q8L7Q5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756630.1">
        <property type="nucleotide sequence ID" value="XM_047900333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Q5"/>
    <dbReference type="GeneID" id="71981063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01185"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="444"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="546" mass="58624" checksum="AEF1925FFAFA028B" modified="2023-09-13" version="1">MVSTDEYYIDEEAPIVHADHLPLQRIDPEDHSIEIIQSPELSTPCTTSRHDPGLEVLGFGLGPSRSGSSSSSHGLLELEPETMTVPVTLKTPCETLVQHANLDQGSIAASVPESSGSGSRIQLQTTAALAIQQSDTKPRSPSDTVELASRPAHRVDSAQESLDSVPQVSKQDATGGDERTSPLTMQTMGQPPAGADAQDSIAQSPTLRKHVIQVGESPVHTLPVVHAASSAADTAITSQRKESLPSFQQLADLADIASQQSTASEARPPIPARQHSHSISSITSQSPMIPYFPPAYPHSAQTSPAGFSTSARSPTGSVGEVLYGSPTLFAPPKYYLDRRSSNATVGTPGFPPPVPSLPLGSSTESHGTQASSSTDGYSTSHTTPIEPGPPPPDGIARILPPPPGMPLIPVGGFKCDYPGCNAIPFQTQYLLSSHRNVHSQNRPHYCPVRECPRSEGGKGFKRKNEMIRHGLVHNSPGYVCPFCPDREHRYPRPDNLQRHVRVHHVDKDRDDPALRAVLAQRSQGAVQKQRRRRTQGSEEDTPDARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8C3</accession>
    <name>A0A9Q8L8C3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757022.1">
        <property type="nucleotide sequence ID" value="XM_047900826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8C3"/>
    <dbReference type="GeneID" id="71981556"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01678"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="18699" checksum="C2FDEFC9EA4A90F3" modified="2023-09-13" version="1">MLTNRERYLENRPIYLGFIAPVIISIQARPTYIVDERHEGIYSNRKRVSALAPLAERMRNAVMNAPDRSSSAPPDLNTSSDPRPGSLLSVVPALTHDGASGSTPSSPDLPSELNPRTPSLMEGQSIYSSEEQTDEDEAGSARAEDFPSPPGSSGEKEAESETREVGEEEDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8H5</accession>
    <name>A0A9Q8L8H5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Short-chain dehydrogenase/reductase VdtF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8H5"/>
    <dbReference type="GeneID" id="71981052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01174"/>
    <dbReference type="OrthoDB" id="2898618at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_7G04540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="32301" checksum="5DF43331EB4A3077" modified="2023-09-13" version="1">MSSNQSGSGRADNEDLEASGLFDVSHVTALVTGGGTGMGLMITQALVSNGAKVYITGRREDVLENTVEKYGQGPGSLHHIVADVSKKDEAIRLAKEIEQKEPEGIQLLVNNAGIARDDHTKFSSAGQPEMSDPKAISEHFLKTEEQQFMDTYRTNVMGQYYMAMAFLPLLAKGTTNTPGYSSSVVYVSSISGAMKDSSMGQFGYASSKAASTHLSRMLATTFAGVKVRVNVIARGVFPSEMTTGSSGSDNKSEMDMNSQNPAGRKGHDSDMAATILFLAGRGGVWYNDQILYPDGVERLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8R8</accession>
    <name>A0A9Q8L8R8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transport protein SEC61 subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_01630</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757170.1">
        <property type="nucleotide sequence ID" value="XM_047900778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8R8"/>
    <dbReference type="GeneID" id="71981508"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01630"/>
    <dbReference type="OMA" id="PMMRQMF"/>
    <dbReference type="OrthoDB" id="420669at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000002">
        <property type="entry name" value="Transport Sec61 subunit alpha isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="13">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO12804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="52109" checksum="D5F55D6A6D8F07CB" modified="2023-09-13" version="1">MSGLRFLDLVKPFTPLIPEVQVPETKVPFQQRIIWTSVTLVIFLVMSQMPLYGIVSSDTSDPLYWLRMMMASNRGTLMELGITPIISSGMVFQLLAGTHLIDVNLDLKSDRELYQTAQKLLAIILSFGQACVYVLTGLYGPPADLGAGICVLLVVQLLTAALIVILLDELLQKGYGLGSGISLFIATNICENIMWRIASPTTVNTGRGPEFEGALPALVHLLFTWPNKQLALREAFYRQNLPNIMSVISTVLVFSVVIYLQGFRVEIPVKSSRQRGMRGSYPVRLFYTSNMPIMLQSALSSNVFLVSQMLYNKLPDNLLVKMLGVWEAREGTAQVLPASGLVYYMSPPLNLIDALTDPIHTAVFTVYMLTACAAFSKTWIEVSGSSPRDVAKQLKEQGLVMAGHRDESMYRELKRVIPTAAAFGGACIGALSIVSDLMGAMGSGTGILMAVTIIYSYFEIAAKEGDMAGLKGMGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9C3</accession>
    <name>A0A9Q8L9C3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_02994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757691.1">
        <property type="nucleotide sequence ID" value="XM_047902142.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71982872"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02994"/>
    <dbReference type="OMA" id="WSQMFAE"/>
    <dbReference type="OrthoDB" id="2019644at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1637" mass="179596" checksum="E9D875D75963E68D" modified="2023-09-13" version="1">MATEDDNDPLHRLQNLQRDLNAANEARLANIERLAAELESSADNLRRLLERNKKSQASRDALTPDTLTIGETQYRITEPFRLNVKQVSDALNLDELEAAQLCIRSQFPDEDNQHGAALSMRAVLRFHEERFVLLDCLRILLLLGNGDEHTAEAYKEAVKELLQGEGGGPTQTSAFWRKCTDGLGDIEGFIADLAALDNKMMQTGQKQQDDDVAWVLSQRLLLTRQHESLAAVMTYLLPRGYVAPEDYRSFLSHAAALEAPADITTHYLPILASGAAHFAEERNEAAVRGIHSLFATGPGQLQWKQSQFKAAAIVIWLAEYSGTFPTPGATDSAGDARTDLFFDALTDGAFSFILGAASFLKPVVWHDPARVAITDFLIGSTVVMPADAPRARADFAALTMAELQTFTEAFVTNMPDALRRLRSTEDEKRRNLLSQSANGAGQTELELERFMVIMAYAYQHDAEAAMDFWSDRESNLYGFLRWVSQRLPTPRVAAFCLLLRSIACDDKSADTAHRFLLEDSTMTSGKLRKSYAVSWAQIFNELEVYVSSLKDRPSAPQGALGPDRAAGELLLEEPETGIMLDAYLGLTAHICRSSPEARQWLLKEQTFHLGEVMFKLAQSATEARIRACCLDVLAALLTDNVVEVRNGMWVLLDTWISSGGQDASSVARVNRPAFAAKHYLQAYANSAESAASLIALLNALVAPTASSPDHTIDELPFPENLGAPHRHAGIDAYVDFVLDAVFARKAGSMLGDGENSLIAIVRYECLHFAFQCLSTFNEDLVQLANTTQISVESTMETKSLTTYARLHPFARVMEWLFDKNVISQMFQTVQQNIDALNNAEPESPVVKATLKAIQILSLAWQLQPTYFDLVRPAILSQKTKAQPVSSTWTSIDEIFLTYLHAIVDIAEYTACRHVEISLECLRLLQRIGSSRRLTDTAESGGATRHGSRIVSVLAPGSALLTMQLAEDFVIHAWDLELDEVPLQVVRANATLDLMNGSLDISSTRPGIAHCLLGFHCRDRDVDVLPASVYSEGRSLFHAIAKCATDAELITQPAGNTSWLMALKRRCLEVILKLAIAPMTSRLVQPNLRAMEFLPALSRRLATTPAVPSWDGLPLQDARVLLQSSSAAVRDFLYIRAGFCRFAAVDLRAAAEQSAFSVQDKIISALLGTVISPNGEELPTVSIFDLFDFFDLETADAFVVPSTKYFDDLDVSSFTKDDAELGRSFDINVTEKALVLRKRELVSKGDIKEPAELEQAENEMRAISAALASQSNFMAIQVARSAALEAWTELVSLMVTKGALETPNLVAFSLQGLLIAAPKYERALSGDLESAAMLAKLVLTLTHAISHASQDSSEQTASVAIERLLAIFRVSLKAITDSATSLALRDVAYRTTCAILASLPKAPITSRTSPTSSSKQLLQLVQNTGERLFTVVTEDAFSGRGITRVSALLFLDSLVSLYQSLKVNTSMLRAFTKLNFVPVLLDTSIGNVAAAFKSEEETVATLAYFHTAMTLLLRICQTADGTQLVLNSGLFQTVDDSKLFSTDPDLGLDIDNPKALQEFYAILADTLRLITAVAVQKSPQPAKLFLQQNRFTVQAIFKQASRGLALDVAEELSRLILATDFLDDDQAAPGSTRVNGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9N6</accession>
    <name>A0A9Q8L9N6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757794.1">
        <property type="nucleotide sequence ID" value="XM_047902861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9N6"/>
    <dbReference type="GeneID" id="71983591"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03713"/>
    <dbReference type="OMA" id="DVPYIPR"/>
    <dbReference type="OrthoDB" id="5591786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014839">
        <property type="entry name" value="Crt10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08728">
        <property type="entry name" value="CRT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="645" mass="70978" checksum="BEF7135DEC335CC0" modified="2023-09-13" version="1">MGPRSLTEAAVIATGVQNSRFGRTTRGNDYEDWPPVAQWRCNLTALSQVHNLYFIAYSAQIYAYIPRFPSQRLPQKPALIVTSQPSSPDLLGTLDQRHPHAINNLVVQHLGSEEVVAAVRDDGDVDAFLVRHVVQAIERRAAADSSIGLDADDVRPIFQSNVGKSAWGLAIHSQARIIAVSANTHSITIFKFGLVNEDGPQAGENTADDTDAAQDRGMDVTHQVLNGTSNIPYISFCNTGDDPNGQWLLTTDISGYCRTIDLHQMQTSQTFRFGRPTSYLASASHDRHNSGWLIMFLDKRSFVAADDAETALGLADGESLPGIKENLNLWDIGDTVANVSNVSNKFSVLRTRRARDSARPSSSAPDSPEGGVPLDDSSQIEDEEVPDAAVEQDLEDSLMSEDAWDGDEDSDSGESAYYADLDIDDEGTEDTASFSTVYGGKRIYGNEPRAFQPHNNLCGDCPCPILHTSVRNIYLLQPSSHRQAESPFTSPTIGFTNALHQLVPSEWAYLNVFERLNMHAYIPALGIVVLASQKGRALVLALTKLSRKAHYPPEMQNPDDPARKKTKYAMRLEHILPFADQEKAGARPFAPLAGIAAGPMQGTEHLTMEMKRWRLMMMYTDHSILSYEISRPRDPQANDVESVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9P6</accession>
    <name>A0A9Q8L9P6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757712.1">
        <property type="nucleotide sequence ID" value="XM_047901980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9P6"/>
    <dbReference type="GeneID" id="71982710"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02832"/>
    <dbReference type="OMA" id="HLYLYAP"/>
    <dbReference type="OrthoDB" id="4838853at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="454" mass="52327" checksum="A8A5233DDD84D922" modified="2023-09-13" version="1">MDASEEKVALERGTMWQQETTHSTGEDMLQQEATDADIRVSMPPEDSQRNTLVADDEKDVIEKETGTDTTAAGTPDPKHLSVDFDTEGRRKRESVESRLSSVLRDSSVLSESDFGELDEQIRQARLRQEQERPQNSRGQTSASGVSTRSQRSGRSMPPLRRKETKLAQKEAHPWQHLGITLGLPMIVLFDIVVPIIIYYAWYNSRVSDWKKECRQQHPDQDPCPIPKPEYDKHILGYAIISFGFGELWILVARMWRLVREREICAPLLSRNVWELDATSWVYGVAMLMALIPFVIGAELELQHLYLYAPTFIMGFLGMLMIVTTFFPFTLPIGINSQARGTKLRPFIYYAAEDFVAVDGLQDREFRVRFNERYETNKMFRRFFLYLTLWWLLGVFVYIGCVSAVIWTLDFHYAFGLSLGVLFSYITIWASVTAVWVNVEMKREHTAYENGEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA24</accession>
    <name>A0A9Q8LA24_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757923.1">
        <property type="nucleotide sequence ID" value="XM_047901777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA24"/>
    <dbReference type="GeneID" id="71982507"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02629"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="14068" checksum="5E785F2185B265DA" modified="2023-09-13" version="1">MEFDETFKFSDKKYAQRARAMTPTTLWELERSTLTSKVKAGTGIGVSTLLLLPTLGVSGVGLAYSSRAVDIARRKVKAAKEEIKRRNLPPYDKTKRDYTIPLGMTFAVVPVTGVIDLFSLGLAGATEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAZ6</accession>
    <name>A0A9Q8LAZ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_03765</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757799.1">
        <property type="nucleotide sequence ID" value="XM_047902913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAZ6"/>
    <dbReference type="GeneID" id="71983643"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03765"/>
    <dbReference type="OMA" id="MCGWDDN"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23284">
        <property type="entry name" value="beta-trefoil_MIR_PMT2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000012">
        <property type="entry name" value="Protein O-mannosyl-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="339"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="405"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="469"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO13433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="745" mass="85649" checksum="A1B4E44BA59E553F" modified="2023-09-13" version="1">MAAQDFQTKATGADTQGGLRQRYAPPQQQQNGNYVPKELDDKLDKKTKQQANSILQTLDDYEFLIAPIVFTALAFFTRMWKIGISNIVTWDEAHFGKFASHYLKREFYFDVHPPLGKMLNGLAGHMAGYNGSFEFKSGEVYPEELNYTFMRLFNGAFGALCVPLAYFTAKELHFKRPTVWLVTLMVLFENSYTTISRFILLDSMLLFFTFTTVFTWAKFHNQRIDPFSVPWFFWLFMSGISIGCVCSVKWVGAFGTALVGIYTTETLWNMFGDLKMPKVTLASHLGARIFGLIVIPMVVYMFTFWVHFAVLENSGPGDAQMSSLFQANLRGTEVGKDSPLEIAIGSRATLKNMGYGGGLLHSHVQTYPEGSGQQQVTCYHHKDANNDWFFYPNRHEAEFDPEAPLKFVGDKDVIRLIHAQTGRNLHSHQVAAPVTKADWEVSSYGNVTIGDTKDHWQVEVINDAASRDHSKLRTLTTAFRLKHVDLGCYLRAGNVNLPQWGFKQIEVTCVKQNKPRDPYTHWNVESHVNERLPPGDPGSYKSPFFRDFIHLNVAMMTSNNALVPDPDKQDDLASKPWQWPLLNVGLRMCGWDDNIIKYFLLGNPLVYWGSTFSLGFFLAMVAWYAIRWQRGYDELTWKQIDHFQYSGIYPVIGWFLHYLPFIAMARVTYVHHYYPALYFAILSFGFCADWLTRQLPSRVQWAIFTVLYITTTGLFWLFKDFCFGMVGNNQQWSHLKWLSTWRMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB96</accession>
    <name>A0A9Q8LB96_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">U6 snRNA-associated Sm-like protein LSm7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03434</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758623.1">
        <property type="nucleotide sequence ID" value="XM_047902582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB96"/>
    <dbReference type="GeneID" id="71983312"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03434"/>
    <dbReference type="OMA" id="PFVQQEE"/>
    <dbReference type="OrthoDB" id="274944at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000043">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="133" mass="14350" checksum="E13835000AC5CEB0" modified="2023-09-13" version="1">MSEHASFRGGGDRGRGGRGRGGGDRGGRGGGNQQQGAERKKENILDLAKYMDKEISVKFNGGREVTGTLKGYDQLMNLVLDNVKEVTRDEEGNTSTRNLGLLVARGTLLVLISPLDGSEEIANPFIQQDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBC5</accession>
    <name>A0A9Q8LBC5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="11 13">3.2.1.106</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Glucosidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_03604</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="11 13"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758649.1">
        <property type="nucleotide sequence ID" value="XM_047902752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBC5"/>
    <dbReference type="GeneID" id="71983482"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03604"/>
    <dbReference type="OMA" id="FNWYNTT"/>
    <dbReference type="OrthoDB" id="410058at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000027">
        <property type="entry name" value="Probable mannosyl-oligosaccharide glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.110">
        <property type="entry name" value="Glycosyl hydrolase family 63, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031631">
        <property type="entry name" value="Glyco_hydro_63N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038518">
        <property type="entry name" value="Glyco_hydro_63N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF11">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16923">
        <property type="entry name" value="Glyco_hydro_63N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040324113" description="Mannosyl-oligosaccharide glucosidase" evidence="15">
        <location>
            <begin position="22"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 N-terminal" evidence="17">
        <location>
            <begin position="34"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="16">
        <location>
            <begin position="308"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO14283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="816" mass="92932" checksum="A6DC71C0F9F15DAB" modified="2023-09-13" version="1">MGKHWGLVQLLSAACAVLAVAEEPVIFSKASNDSLLWGPYRPNLYFGVRPRVPKSLLAGLLWARVEDFVSVQGNTRYTCEQHEIDGYGWDKYDPRTGGIQTIKDKGNGLDLETTFVKFDEGRGGWAARIRGTPRTDGSLLEDNQFSTGGGDGRYAVFFAVGAEGLGTVEPQEAEGAEELGYAGDVVFDGQTQDLGEFKLTITKGTSKSHPRHKHPSDKAKPLDRTFVHSQQVQEEALWQTKPLLFRSMKTVIDAYIEEYTQEKMPPPWQTYTIENKPGQGNMHLVQKVFEGAFEFDVFYTAADAEQKTAEDFNKAIKEMAAGFDKRYPAVHKPETPFTDSKYDVFSKSLFSNLIGGIGYFHGDQVIDRSYAPEYEEENEGFWQEAEEARQRNQQKLEGPYELFTSVPSRPFFPRGFLWDEGFHLLPILDWDAEVVMQILSSWFNTMDDDGWIPREQILGSEARSKVPAEFQVQYPHYANPPTLFIALEALVDKIVGKAGSGAALEHKVGTNTLATPESVKAWLQQLYPLLQRNFEWYRKTQWGDIKSYDREAFNSKEAYRWRGRTPRHILTSGLDDYPRGQPPHPGELNVDLISWMGLMSRNIHRIAGFLGETDDEAKYGKIAEAIRRNIDDLHWSKEHKTYCDATVDDYEESVHVCHKGYISIFPFITGNVGPDNEHLKDILDLIKNEEELWSPHGIRSLSAKDELYGTDENYWRSPVWMNMNYLIVKELYNTAQQPGAHQKQAATMYRSLRKNLVDTVYRSWLETGFAWEQYNPETGAGQRTQHFTGWTSLVVKIMAMPEKIRVEKKGGGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBX1</accession>
    <name>A0A9Q8LBX1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758896.1">
        <property type="nucleotide sequence ID" value="XM_047902831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBX1"/>
    <dbReference type="GeneID" id="71983561"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03683"/>
    <dbReference type="OrthoDB" id="3643542at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="31862" checksum="348E4AD03F06DA9C" modified="2023-09-13" version="1">MFPLTPSSPSPSMTFLAPALPFLKWKGTFQQYKYLATIPQECSPPIMTTSYLATSLNFGNPPFSRLNELKNWLKGYITTPDFFTKEPRHALDDLHAALLAVAKEIGMKLDPELEATIHTAGDESHSIQCDEDSFWTTRVLDVHKLCTTGLIGIKTLSRERVIALLLIARDEVQWVANEIRRLDVHCKNAADLKGCKNRESFSYYPSPRKELAADLKNLKGSGVMVRLDGKAVDVDDMDELLDGSEIKDEDMIDAEKEIEEERRDSKDIVGNVKRENLDYLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC40</accession>
    <name>A0A9Q8LC40_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_08044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LC40"/>
    <dbReference type="GeneID" id="71987922"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08044"/>
    <dbReference type="OMA" id="LVHTTNM"/>
    <dbReference type="OrthoDB" id="5419666at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="75"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="27647" checksum="345FA8E10FB321A1" modified="2023-09-13" version="1">MSLVRALTTRRAKPDAFGNVQHVGRAASQRAGKPVHRSQISSPVALVSSSNPLSYEAPDIAGTKPIEFRKVSSESSAASSHSAEDSDASTLSINSNTDASSVEESSPITPEPEPNHLSCYFKTSSSDSSARTSLDAPVIPQRVPSHSKKAHERLHRKRSVQRLMSPPTSIILRRESSEMFQAVELPRENPFTGELAQLDEVAEEFSHAVRDTEADADATCMVMNDLAHFSASDYLAEIHSLIYETFLAEGPSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCA7</accession>
    <name>A0A9Q8LCA7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_08435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
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    <dbReference type="EMBL" id="CP090165">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907583.1"/>
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    <dbReference type="GeneID" id="71988313"/>
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    <dbReference type="OrthoDB" id="3485059at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF1">
        <property type="entry name" value="HYDROPHOBIC SURFACE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="18546" checksum="7305B728D961A295" modified="2023-09-13" version="1">MLRLSKFAQMAANAKNALTSRDAASTQQNLETINTQVEKLAATLKAYAGGLLAASGISSDQAKLSIDMRHTIADANAAQVVTEDEAKEIIQYLNDTIEPSIRSTMTALQEKKAELEKAGLKGTVSGDMADLRKLTRELGEVLLSKSPEGTRKSGEEVMAKVDADFEEALKAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCM9</accession>
    <name>A0A9Q8LCM9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08718</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759318.1">
        <property type="nucleotide sequence ID" value="XM_047907866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCM9"/>
    <dbReference type="GeneID" id="71988596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08718"/>
    <dbReference type="OMA" id="FKLWEAQ"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="285"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="977"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1128"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1128"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1147"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1187" mass="131171" checksum="B6A2F332698FF307" modified="2023-09-13" version="1">MSFACPIANTPSAARVRHDSKVSSGRATPSLARINTNTSDPTSDDQATHSFNTGASGSFGSSFGHYRYDSQVLTSPASVQGSFGASGLSTPLWSNVQSPLLRTRTESRISIRGWVNELILIPDIRSKFGRRRAQKIAKGDRRANKPKQANLLDKEGTKKLSNFWGLAEASKVDDDQESSEEEESSSPEVRLTFEQFIRHDNTRAQDASENTIRARFHPRLSSVSEHRVVRHDSGVDIIMDASRLDPGSRIMADLQEKTRRVKDAKDMYETIVRNAERSNTSVPPYEFLELIGKGAYGRVYKCRDKRNGNLVAIKISNIDDLDWDANYAIQNPRDANIKDFRNEVSVLKQLRDNNVPNVNVIHDAFDLHSQLWIIADYCTGGSVRTLMRPFEKNGRPAGLPEHYIIAIARELAMALKGMHDLHIIHRDIKCANVYITEDGEIQLGDFGIVGNLEDSNAKRKTVIGTPHWMPQEMLLKLDNSTLEVGYGTEVDIWSFGITIFEMATGAPPNTKVAVDSLGDMLKLSGPPRLESEEYSPDLRDLISFCLNLDAKARPTAKDVLEHPAIFNTSEKYPTSGLIRLVERFKMWEHGGGSRTSLWIAGPTDPKIQLEGEDAPIVEDVDPLDGWNFSTSEDFDRRFSQMPIVTEPLGLEAAEAQAGSRLPPLSTTNLSVAERIKREWVDKSATRGEKSLAPIFDQNVGYQIATPVEEPSPSPPSDLPLRNFTSNAPTRESMIEIDLDAADHGGTATSTFALHMDAINEDTVKPASRHHDDDEDEEYQYGQASDSSKRDTMAWTFPPAAEPAPVLRPLAPQTKRGTMDWSFSTAEPVQADEDDISFGPPPFPASDDLPPGFRPGLKHSTTEPIGHFGGGDYSHSMGSLDPSPLRSSVSSMIDLDMGLVDPPIRLHDPADIIRPSTASSTAGSTMTDMTSGNPFDLEDDPIQNESDRNRFSYHKQWTSEGGPIKRHSHKTMQMHSRGTSLSSTETDPEHFLSSNGGVDDRRPSLPFGADIGFSPDDSNPWPDFSSFNGYDTSPEYMSAMNDLPHLEDPMPSIEPLSFNGNPLSATDSFGTELPVPEIEFPVIESLHTDALAEDADPQMLIDQFERSLRDLDGAISGSWRALRQYANIDGDDDDDLISDNESGFESMKEEDEGDEVEGLDLTVRRKPRKPEPRSPSSVTSTQNDDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCX7</accession>
    <name>A0A9Q8LCX7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759551.1">
        <property type="nucleotide sequence ID" value="XM_047907242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCX7"/>
    <dbReference type="GeneID" id="71987972"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08094"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43630" checksum="0F5C12BFE3CE76E3" modified="2023-09-13" version="1">MEDELARLDAEKAKILKERGAFLGGVKRRHDNGRRTLQALRSRQNAEYRITVGIANQKYQAKLADLTTRREEVLKSIPDPQLDGLSDLDDDESQPERPSAELPPQPPAVPPLESPIEAQDPPEKSVQEVDNGSSSGHSPPGTSVWDENTRESSSPAQEEEDLGLNLPVISPQTREGESLSGEFPTVIYMKGHFHEIKCHNCGTNSTRNGKDFFLGARGILDHIRIAHERLYPKHDFRELDACIVRTLDREEVQKLENGIQPADPLVKCGPQPFQRPQIPDAQPKISHPDVPGNVIQDEDDEWFRISCRIYRGNADDGLEWYDGEQGLWEHIWDCHPQMLGEYDTETWDVLEDVGRIAFKEPLEEGQVYSICQHAMENPRRRGVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD26</accession>
    <name>A0A9Q8LD26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759549.1">
        <property type="nucleotide sequence ID" value="XM_047907147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD26"/>
    <dbReference type="GeneID" id="71987877"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07999"/>
    <dbReference type="OMA" id="IDWAYFD"/>
    <dbReference type="OrthoDB" id="3649380at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="26670" checksum="CEE43B33F2C730E8" modified="2023-09-13" version="1">MALERLTESFAVHLRGHDTTAVQEISVPETPGNALREAFDTGINSQSATVPMPSDRLHTIETHIDNLNEMIQALRAQWLAGSRHPGPQRPISSTQESTLSSESTSESAESSSDTSYTSYVDLAFLTSLCDEVAELGEALSNQARYLLDLEQTSPTEAESEPEYQAEADSRRPLLTQGHLFAPSSLQTGVEPRPIPVSRRAPVASAMPWDATSDVVMDQTGIDWAYFDQVLHENGHQEPDPGPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDB9</accession>
    <name>A0A9Q8LDB9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_08656</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the RPAP2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759655.1">
        <property type="nucleotide sequence ID" value="XM_047907804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDB9"/>
    <dbReference type="GeneID" id="71988534"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08656"/>
    <dbReference type="OMA" id="IQAQKDT"/>
    <dbReference type="OrthoDB" id="2590500at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043175">
        <property type="term" value="F:RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039693">
        <property type="entry name" value="Rtr1/RPAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007308">
        <property type="entry name" value="Rtr1/RPAP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038534">
        <property type="entry name" value="Rtr1/RPAP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732:SF0">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04181">
        <property type="entry name" value="RPAP2_Rtr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51479">
        <property type="entry name" value="ZF_RTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RTR1-type" evidence="14">
        <location>
            <begin position="84"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="233"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO15289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="31452" checksum="825860828A09E7D2" modified="2023-09-13" version="1">MSTKVPVKSILKTQGVKKTPTVTDEQKAKVEKDKQNLNIALKHAYLIQQHRKHVEAAILDAITTLIDLPAASTFTTEESETYVKLIRSFQPSDFDSLIEERRVDERCGYGLCGNKPRCQTMGSSVAWKLKKGMSDYCSDACAKKGLFLKAQLSEVPAWERLPEQQPDIQLHADDRPADTDTAQRRANRTARVDEWRKKVASNEELAMERGEKASSMRPNQVMADMIVEKNPKPFEASSLQAGAGHFNTIEGYQTKRYNKKKKGEKRDSDDSETDDDAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="71987770"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="232" mass="25692" checksum="1060AAA03D2291F9" modified="2023-09-13" version="1">MQEISRQPDMHCHPDSVSPTVALQQSTTQLVPSFGSWSHIQTSPCRLGPREIMVASPQGQHQIMTCLPDTGSTHDFIVPSLVHQLEMQRFVQPVRQSVLPANQHTVMVDGVVWLQFRIQNDFETYGRWSYLFAGLDYPIVLGRDTICQIGLFGCRCPEAGNNVALRMMSLGKQTRGVVGAQKQAKQESNRKNRDKTRAEQEADMQELIAKREAEAMAAANATAAGSGTPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE71</accession>
    <name>A0A9Q8LE71_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
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        <location>
            <begin position="192"/>
            <end position="354"/>
        </location>
    </feature>
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        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
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        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
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        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="354" mass="38395" checksum="C320999B7FD123E2" modified="2023-09-13" version="1">MVDSDGNSDQQEKEIKKPYRLTGPLVVAEEAMISVVPEFIPYDTFMPFTTTVIAEEDFPRFIQHVNDRFMQKSAKGDDDTTKQGSKVSRKDKKASRVAKRASTVLKKVLQKAKSGKRQVESNTEDNNIKARLPNDRVCRRDITMAAPFVSRLQKVDVIGGDGESVFLRSDWETEDEDYFELFNPYANVPPPSIGGATIPPGSKVGSESASDATTAHFSSSPSAADTTTGRDEREKPYKTTQGPTEVLHDESDTAARRAVRSASPAIPSASEPKTTGFRTRKRKAIDEAPKDDARAGKKVTAAAPSRSAIDTSSNMPADDRGESANPGSNEQTGATGGMKNMAISGTETTLRKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEB3</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEB3"/>
    <dbReference type="GeneID" id="71984791"/>
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    <dbReference type="OMA" id="MPNLLWW"/>
    <dbReference type="OrthoDB" id="3650832at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="50335" checksum="C4FD6D1426E1737B" modified="2023-09-13" version="1">MNWNIRNCRPLMAGCTTFLMLVAYFLATGIATAKADVGRVHARDLSTTSDFDGDLTNNASNATHAPILFKRADGFLVDAADFDTFMLYVCNGRLFTDAMCMDEHYLSANMGLQQKEHNYVEQFIDSPEWTMLEHGEVFLVGEKYPELYALQGLRKLNGMRSDTNRETRVFDLTSDQWQYSRHVQNRPYGESAHPTFAYFEHIMKSEVHPRYNGGVIIIPGARSPHYQVAALGLTQPYPLISKWSDSAYLQDMANRGETAKRENYVIEPPTWFLLKDVYGPRDTLAVITRCLRYHGWTDPHMPLWQDRMTFPIGSACYDAILGTQNSAGLAWFLIEHKFKYDITTLASVTICSDPHVNVGSGDHPPVHMPDFNDELGATEMPNLLWWAGTLSSALTWRNGKNLMNMRGENSAYEAGQIPNILQKASWDTGRVGSMPSFPHKLTPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEN9</accession>
    <name>A0A9Q8LEN9_PASFU</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LEN9"/>
    <dbReference type="GeneID" id="71984980"/>
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    <dbReference type="OrthoDB" id="3834359at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="41548" checksum="DBDD0B008AC26A03" modified="2023-09-13" version="1">MPSHHIFSIPQELQDMIFECAYSRSGPYRELAHMPSQRLDYATFRFIPRTHKIDSFLISKRWFLAAARAYVERQTVPMSIDSRSHLFNTRVLYAFATTVSAYPADLLRAKQGQLPRLRRMQFIPYVGNRPGPSEDGHLMTDEELRGLELFRGLRRWQNEFPGIAFEVKEGPPSESPWERMEALSMEEVERLMGLVQGEAKRAEAGRGQMLHYINSMLSGISWRKSKGNMRLYARSRVRTDGSSLIQKDSEEMLEDCLRFLMRAQSSLRRRWHMRVHQAIQWQIWLVYRLSGKRGSFALKAVMMVMWTVAIYKLVHDVRGWVGIVDRLMMLLAKIVVGMVVSRVSRMLIRRFSNDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFQ3</accession>
    <name>A0A9Q8LFQ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetylglucosamine-induced protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761006.1">
        <property type="nucleotide sequence ID" value="XM_047903356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFQ3"/>
    <dbReference type="GeneID" id="71984086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04208"/>
    <dbReference type="OrthoDB" id="10053431at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF4">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="263" mass="30273" checksum="3C58A699D5E0C4C9" modified="2023-09-13" version="1">MQAVPDEGILTSVDECTDLHDQTAMACETVPFWNVNVPKASWTEDCPEFLRYAFDNEKDRGILSTPDSQYHRQSWQQVKNIILENRLADFDRVPSELRLYREYCAKLVREHGSIMNFVMRERLHWNDLSPSGEAFTNPEDYKILYNDWPYGIDKRIVHLVVWTKFHLPADPSSDIGDMSSETRALVDDFVEQTFASKCGRENVIWFKNWAGLKSVHAVEHLHVMLFDPDPKFVEGITGGDVPLFREVKGGRYEGDVGGIKLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGA0</accession>
    <name>A0A9Q8LGA0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761260.1">
        <property type="nucleotide sequence ID" value="XM_047903918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGA0"/>
    <dbReference type="GeneID" id="71984648"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04770"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="72" mass="7139" checksum="83B5E5578AFE0F0C" modified="2023-09-13" version="1">MPSDKVSTKTPPSKGGGGGGGPYGNGPGPSGDPRPQMPWCDCGCGGDPVLKAQIAAERGSRGATQFSHIGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGI1</accession>
    <name>A0A9Q8LGI1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidyl-prolyl cis-trans isomerase-like 1</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04933</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761341.1">
        <property type="nucleotide sequence ID" value="XM_047904081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGI1"/>
    <dbReference type="GeneID" id="71984811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04933"/>
    <dbReference type="OMA" id="GMVEYWR"/>
    <dbReference type="OrthoDB" id="10264753at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="133"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="10">
        <location>
            <begin position="502"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="649" mass="72442" checksum="B004134CEC97CF7E" modified="2023-09-13" version="1">MEHENLELSPQPNMAATADEAPQGTKRSRDEAEGNGVPPAGGDDESESSDDDIGPALPSAEQPQKKRRKLPYEKQYIAALPSATRYSKSLMHKEQLSFVNITPHTAFLITSSVDGYVKFWKKTSGGIDFVKEYRAHEGEIRSVTVSSDGRSYATAGADNTIKIFDVATFDLLAMLEPETPARCICYVHGNGTSYPLLALSSETDGSITIYDGRGENQQPMHTIASLHRKPVHVMAYNNAYDCVISADESGMIEYWQPSGSFEKPDNVFEIKSSTSLFEFKKAKSVPSSITLSPTGEQFATFSFPDRKVRLFDFATGKLQRTYDESITTITEMHQAGTLTKQPLEAIEFGRRIAVERELEHPAVRNRINVIFDESGHFVLYGSILGTKVINTFSNRVVQIYGRDEPFRPLNLALYQGQPEKKVVVTVQMATSDNPLLAEAEARDAMLVSTGSGKVRFYMFTDEDNVSKSDRDIHNEKPRTLNATRKAEEEAREARIGTSATIHTTMGDIQIRMYPQHAPKAVENFTTHARNGYYNGIIFHRIIRKFMIQTGDPLGDGTGGESIWGKEFEDEFTPELRHDKPYTVSMANAGPGTNASQFFITTERTPWLDDKHTIFGKCIKGMDVVHMIENTKVWKEKPVEDIKIVNVSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGL2</accession>
    <name>A0A9Q8LGL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761622.1">
        <property type="nucleotide sequence ID" value="XM_047904855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGL2"/>
    <dbReference type="GeneID" id="71985585"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05707"/>
    <dbReference type="OrthoDB" id="9992270at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF8">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040209997" evidence="1">
        <location>
            <begin position="17"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipase D N-terminal" evidence="3">
        <location>
            <begin position="59"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="190"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="614" mass="69005" checksum="9B8CC4B35924EF3B" modified="2023-09-13" version="1">MQVTAAFVALLAAAQAEYHANINYRSPSHVHNLAISIPKVMKRHGGASHQDPAAVNFTHGVASGDPYAESVILWTRASPTMDNDHSNVTVSGTAALYNHETAQYVEASKSSICVEWTLSPDEDLKHSAAHGKAYTSSDIDYTIKIEAKGLKPYTWYWYQFTVCDSNNKSPVGRTKTAPAKDQDVDNIGVAVFSCSNFPTGYFNGYGNSTRKDNVEYVVHLGDYIYEYATSSPTYGRAVRPEREIFILYNYRARLATYRTDLDLLLLHSSIPGFRPGTIMRDGSSGLNNTEESFEENGRVSVDQRKMNAVRAYFEWMPIRQVDMDNNLRIWRSFNLGNLFDPIILDTRNYDRSITDLGWNEDYIPEIMNDAGRTMMGSIQENWLYNTLKRSKATWRIIGSQVVFSTINATRWFGTDYNTDAWDGYMANKNRTLKTLYDNNIGNNIVLAGDTHENWVADLTWLEEKDYDQQSGAGAVGVEFAGTAVSSTSSCGDEFTINSCNNQSRNLVADNPELQWQEGYYRGYYEMQISKKEVRASYFGTPSLVTRNGYEVPLANFTIAAGDNRLTRPVGGESGVRNGALQRKETTVSNLTLDTNTGRWFEHNENVLNIPRQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH88</accession>
    <name>A0A9Q8LH88_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05509</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761785.1">
        <property type="nucleotide sequence ID" value="XM_047904657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH88"/>
    <dbReference type="GeneID" id="71985387"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05509"/>
    <dbReference type="OMA" id="CGRRVHH"/>
    <dbReference type="OrthoDB" id="3647976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="42"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="27015" checksum="97AD77E58FA23FFF" modified="2023-09-13" version="1">MGYPPDTPPDHITQEHFPFVHLVCPAHVMDNPCDACGRRVHHIDCIVIAVDGVCPNNGKRNNLIFSPAGVHVGLGNELSGGYTLIHKGATHQTAELQAGIKGLEIALCIVSEDLPDNTARMGTLVIKTDSKYVFEGITDHIKKWKLNGWQTASKKPVANKELWLRLAKTVEKDADWWANVGYHGVKYYDAERWLDENHDGNLDEKYDAVQCCIEQANAPFMWNGREWLFPMKDQDRNTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHP9</accession>
    <name>A0A9Q8LHP9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761964.1">
        <property type="nucleotide sequence ID" value="XM_047905269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHP9"/>
    <dbReference type="GeneID" id="71985999"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06121"/>
    <dbReference type="OMA" id="FDRRDLW"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="372" mass="42549" checksum="01B9449433727AB8" modified="2023-09-13" version="1">MSVAHGTHMRKWLLSLPPVEYMIQYLRETLIGALKCGPIPEHIAFVMDGNRRWARKSKVETVEGHNMGFEALARILEVCYKSGVRVVTIYAFSIENFKRSKYEVDALMDMAKTRIVQLSEHGALLDQYGASVRVLGDRSLMRQDVLDQIDRAVDMTKHNDAALLNVCFPYTSREEITHSVRETVRDFTKPPSRPALKRPFSETHIQRNILSRQLPSVAEEDQLPKEYLPFSQSRSDETPIPSDSDSAISEQDLEASSNLQPASSRTSHSPSPNLKPTSRSSDLPDPEDITVATLTKNSYTFDAPPLDLLIRTSGVQRLSDFMLWQCHEDTEIRFLDCLWPEFDLWHFLPVLVEWQWRQKKLAQEGKVHLKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIZ6</accession>
    <name>A0A9Q8LIZ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_05854</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762633.1">
        <property type="nucleotide sequence ID" value="XM_047905002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIZ6"/>
    <dbReference type="GeneID" id="71985732"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05854"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF4">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
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        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
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            <begin position="361"/>
            <end position="386"/>
        </location>
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            <begin position="407"/>
            <end position="427"/>
        </location>
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            <begin position="433"/>
            <end position="459"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="EMBL" id="UJO18267.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="60667" checksum="2157FFEA3AB10DFA" modified="2023-09-13" version="1">MPRHRSRSSLDLTRMYHESAKSMRVNPTMSAATLDDMFMTEPTVRGEIGEITRHDKFDMTRMGKKQEMRRVFRQFSILSFTCVIMGTWEFLLTANTQGLVAGGLAGLFWSYLWTLVGFGLIIASMAEMASMAPTSGGQYHWVSEFAPSSCQKFLSYTTGWLSSMSYQAGNASGFFLAGTVIQCLAMVNYPDYAAPNWQSTMCVLAVVLISGIFNIFCSKWFPVMNNISMTFHITGFVAVVVVLWVLAPHPPAREVFIGFSDMGGWSSMGLSVMVGQISAIASLGCSDAAAHMSEEVSDASLSVPRSMVWTFMINGSTGLIFLVTILFAIPSVEDAVADPTGYPFLYMYKVAMPNSNVGTNILTIVPVLMLMVGNISFTASCARQAWSFARDRGLPFSRWISKMDNRVHVPVNATYLTLACTTLLSLIKLGSNAAFNAILSLQLSTLMASYLIAITCVVIRKIQDPDSLPRARWSLGRYGLPINVVAMLYSAFACFWSFWPNTTLVGTTSENLESFNWAPVIFVGVFIVAMVTYVVQGRFVYDGPVALVKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ82</accession>
    <name>A0A9Q8LJ82_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762865.1">
        <property type="nucleotide sequence ID" value="XM_047905781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ82"/>
    <dbReference type="GeneID" id="71986511"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06633"/>
    <dbReference type="OrthoDB" id="3630522at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="23326" checksum="0D6FB6B615B54640" modified="2023-09-13" version="1">MSSPAISSCTSATRIVSPATLSPPNNPTRTISTNKDDDIMPPSSPTPQKKQLSHGSSASSSATMYTASGALGNNNNNNNNNNNDNDLQPQRSPHLAPKSLSSPTTASTPTPTIPSRAPTPACERSHSQPQPDLLIRTSTRSPKPEHGKRPSFKRSLSSLWKVLDPPELSHNTGALHNIAKQFGDDSAHRRRSASPGDVEREHTLLATISDKVYKQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2K3</accession>
    <name>A0A9Q8P2K3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">proline--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_01859</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="4"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755167.1">
        <property type="nucleotide sequence ID" value="XM_047901007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2K3"/>
    <dbReference type="GeneID" id="71981737"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01859"/>
    <dbReference type="OMA" id="NCDYAAN"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000066">
        <property type="entry name" value="Proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF2">
        <property type="entry name" value="PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="84"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO10801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="624" mass="69616" checksum="A90A6E0CEBD5D354" modified="2023-09-13" version="1">MSVQHGLKTLWCGNAASSFVRSIHAQRRALHHDGRNRLSNFWTPTQTRTANTADNAAEDGHDLLVRAGFLRQAHSGIFHLLPLGLRVQDKIEKLIDKHMQRIGASKVSLSSLSSQHLWEKSGRLDGRNKELFQLKDRKDAKYLLAPTHEEEITTIVKNAVHSYKDLPLRLYQISRKYRDEARPRQGLLRGREFIMKDLYTFDVTDAQAMSTYEEVRAAYKAFLDDLNLPYLVANADSGNMGGSHSHEYHFASARGEDTIITCQTCDFSVNEELYFPAHRPAQTEDVETAPTADARQPADDVPYQIWYGQVSESLNTTDDASQETSLDTSGSAPQLKTLVQVFLPNGPYEINLHAMKKLVPSIDTTETVRPEELFGRLEESKTLNDPAEWLVFRDPRVPVAAIINTVEHWTRHGQNRQISQTAHSAIPDIDVSPFTLTNAARDDLCPQCGTEGSLTFSRAVEIGHTFHLGKRYSTPLEAVVQDENNQQVEIAMGCHGIGVSRLLGASASLLADSKGLNWPIAIAPFSVLVVAAGGVSSTEVGALYDEVDASLSSNRIDAIIDDRDRPMGWKLNDADLIGYPFIIVLGKAWKQRRAVELQCRRLGIKEEVPADQLVERILQYSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2T7</accession>
    <name>A0A9Q8P2T7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00128</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755407.1">
        <property type="nucleotide sequence ID" value="XM_047899276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2T7"/>
    <dbReference type="GeneID" id="71980006"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00128"/>
    <dbReference type="OMA" id="FQVPPMH"/>
    <dbReference type="OrthoDB" id="5589195at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042281">
        <property type="term" value="F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF1">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="67523" checksum="646440083BA561D2" modified="2023-09-13" version="1">MANSHRPRKRRRNEISSSSSNGTIAVDPATKRDTPAFPLVAFLWPAKGNTVSQWVVLPCVLLVIGLFRWCTAIWPYSGMGVPPLFGDFEAQRHWLEITIILPVTHWYFHDTTWWGLDYPPLTAYHSWILGQVGSFINKDWFALYQSRGLETPDLKVFMRATVYVSEHLVYVPAVIICVRNLAKLHTINSWESTIALTAILMQPATILIDHGHFQYNTVMLGLIVAAISSMIAGRNLWACIFFVGALGFKQMALFYALIVAAYLAGSCVSPKLNVLRFAGIAIVTLLSFALLFLPIMAGTFYDTYRNIQLPSDVSLPPLLQNSPIQLSEKAWYYPYLVQLTQVIHRVLPFDRGLWEDKVANYWCALHTSGLWKLDRSKAGQARLQSTALQWTVLSQVIPCAVIFFKPKKNLIPVAFAAASWGFFLFSYQVHEKNVLLPLLPMTLLLATKDGMKPRIRAWVGYANLLATWTLFPLLHKDELRIPYAVLTPLWAFLLGLPPFSISAYTTSAEDGGLDILSKLIHLGTYAAALLWHVGELFILPPTNKPDLWVVGNVALGASGFFITYLWCLWQLLSDHDFLVMVGLANRETRPKVSRISKKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3I9</accession>
    <name>A0A9Q8P3I9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756349.1">
        <property type="nucleotide sequence ID" value="XM_047900138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3I9"/>
    <dbReference type="GeneID" id="71980868"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00990"/>
    <dbReference type="OrthoDB" id="10538559at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="388" mass="41916" checksum="7F323205F5145A2E" modified="2023-09-13" version="1">MPDKKLEPKQSGFLGMFKRRDSGLNSTHVPSNGKKEQSTTPSPRRAYKPRYAERDMILSMPVEQRPDLVAKANEVRLQGVCSDIGFSTAASLHSGSRNSRIGSRSWSSRHMPTHPNLHLKLYGGASAHAAGSSVSSLHNNVLHGSGMNRMASSPASMRDKNTHASHAELSSRALEQYRPSPRSYHSVPAMSQLDTTSIEAVNQAYAELGISGADFELERALRMSGMDYDLSDVAHVGQRSMATHGTMHQRPPYFGHNDTLPNLKGGKGKGKQATRSLTGVPPSIAGSSDYGDASEKDDLDDPESYILRTSASQTSALIAAHEHPTHDLESSSSSFAESYGNRVANDFWSRNSSERTTSTSTLMTSHSETSVVRPATAESHTPDVLGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3L3</accession>
    <name>A0A9Q8P3L3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Superoxide dismutase</fullName>
            <ecNumber evidence="2 8">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00606</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756424.1">
        <property type="nucleotide sequence ID" value="XM_047899754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3L3"/>
    <dbReference type="GeneID" id="71980484"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00606"/>
    <dbReference type="OMA" id="HNQFWEM"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="9">
        <location>
            <begin position="49"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="10">
        <location>
            <begin position="143"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="28496" checksum="DC74A93B91D8A5E7" modified="2023-09-13" version="1">MQLFNYSIPLLGFWQQAGDWMSNTAQSRLDSIQQSLGAGPNTQNNTMAYSLPQLGYSYDALEPHFDKETMEIHHSKHHQTYVNNLNSLLKEHSQLNTLNVDDLVTKLDQVPQDKQKGVRNNAGGHSNHSFFWQNLKLGTSLDGDLETAIKKDFGSVEDFKANFEKAATTVFGSGWAWLVSQNGTLKIVTTANQDSPLMGESVAGAKGFPIVALDVWEHAYYLKYQNRRPDYIKAFWSVVNWDFAKQRFSQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3M1</accession>
    <name>A0A9Q8P3M1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BTB/POZ domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756203.1">
        <property type="nucleotide sequence ID" value="XM_047900105.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71980835"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00957"/>
    <dbReference type="OrthoDB" id="1893551at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="336"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="390"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="915"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1150"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1196"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1294"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1507"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1356"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1378"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1439"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1516"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1527"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1558"/>
            <end position="1571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1571" mass="173102" checksum="0803EAFFD4A085E8" modified="2023-09-13" version="1">MISLLWKAFYDDHVDTFRQLLETAAYNARPYGARGASSHRSAAIASPVQPGTSPMNTRSRRTATPKTAVNAGSALTKENLNMLDGAGMTLLHYAVSSVKETAIDFATALLEHPIIDLYAQDEENGWTALHRAFYFGNITIARFILERDAGVALSKLRGNSRPTLSLVKVKDKEGLGPLDLYAATIKDRTLRPALSTRQRSGSNGSDDERPILDPSDGHGPSPVKIPFIDVHGDQLFHFGSNRNVSLGFGDQDDRQFPERINLRRPEHLVRRFYEEYLDHHESRWSGHDPAYQSKADSVSNMWVEDIPWMPKSRPLEIQDVHMSKLHTAVLTTDPEANLYMCGHGQGGRLGTGDERTRFHFVCIEGGALAGKRVATVALGQNHTLALSDDGEIFSWGNNAYGQLGYNLPKAPNDEEPITTIPQQIFGPLKRETVIGVAASRVHSVAHTATSLYVMGKNDGQLGIVDSDARSLDMQVAPRRVAAALFTSAIASVAAIDSATVCLLDNHDVWVFANFGYAKVPFPLDGFTNYFLRQSFLVTTYDSAPNQISKVTAEGDTICALSTRGEVYTVSISQRQDTKASVSTTNPTKIRGAISTPQRIWSPKKSSMAARDVGLDTDGSIILSTEEGSVWNRTKRATMKDASNVATSEYKPKDYKFSRVPGLTRVMAVRSSGHGAYAAIRRDCDVLQTQVVVEDPTLWKDLFPLLSLSQLIDHNIESEDDTSRHRFWQGTKRPSEVLLLRKAVLRCADIGADLKTLFENGWNRPATKYDALLATTSSEVRIPVHRWLLTARSRVLRRGFSNLCEMSTFTIPDFARSELDDEGRVVITFQGLDLLTILDLALYIYTDTVVDFWHFVKSAPKMAYSYRQVRTELMKVATRLELAKLEPAVRQMVEPRPCLDMDMEIAHGDPAYFYDGDVVIELEDDEVKVHSTLMRTRCPFFEGMFMGRSRGGWLAGRDDHAEVNVDLKHINSKTFSLVLRHIYCDSGEELFDEIVSVDIDDFLDSVLDVLSAANELMLDRLQQIAQAVIGRFVNVRNVCDLLNAIAPSSVREFKDAGLEYLCLNLEAMLQGQYLGSLDEDLLLELDKVVRGNQLAYMPFAKSGRAARELLDQHPELAATMDRNKRAKVDNIALKAKYDRFVSFAPGSLDEDNAASPMQLKTRRRSSNTVRTSTDHPSLRAKASTKDMMFAMDEEVDSGIASPQASPSIRPMPSPRGLDPQSTPPDDVWFNSRGKALPSPKLAAQSVQDGFITPRTPISPLMAGKTPPNAGRPWTLTPLPGQKMEMKDIMAQTISGRKSSITQGLAAAKGSEDPMDVPAPFRLPGPKMSQKDRKRMQQVHQASLRASPAPEEAEVKSFSWQAVSNQKRPGLKDVIECESTSKGSPSRSPSTPTLTTRQTVANPKASSSSKPAIGPASPSLRQLSVTEHKTMATNGAEGKGQANSVSHVSNSKPIPQSVRHQPVVDPAWGLSMSEIVAQQELEKNAIKEAAAKRDLQEIQAEQEFQEWWEKESARVQEAEQQATAAATKAPKRNRGRRGHAGRGGKGTGGKGREHAANGGEISTATSSATKPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P437</accession>
    <name>A0A9Q8P437_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_01927</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756772.1">
        <property type="nucleotide sequence ID" value="XM_047901075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P437"/>
    <dbReference type="GeneID" id="71981805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01927"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.150.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004039">
        <property type="entry name" value="ATP synthase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="13">
        <location>
            <begin position="190"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="440"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO12406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="62115" checksum="6397F4BF6C7A36AF" modified="2023-09-13" version="1">MFRNAIRTSARAAGALSAGSRIQAQRTAPAAVNAYRGYAADTKASPTEVSSILEQRIRGVQEESGLAETGRVLTVGDGIARVYGMSNVQAEELVEFASGVKGMCMNLEAGQVGVVLFGSDRLVKEGETVKRTGEIVDVPVGQEMLGRVVDALGNPIDGKGPIKTTERRRAQMKAPGILPRKSVNQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVALDAMLNQKRWNNGTDEHQKLYCIYVAVGQKRSTVAQLVKTLEENDAMKYRYPNVTVSWSNSADQFSASSSPPPLLRLLHCSTSRLSPLAPWGDSSEWFRDNGKHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDKFGAGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLESELFYKGIRPAINVGLSVSRVGSAAQLKSMKQVAGSLKLFLAQYREVAAFAQFGSDLDAATKQTLSRGERLTELLKQKQYQPMAVNEMVPLIFAGVNGYLDSVPVNKILQWEADFLNHLKSNESALLEQIDKDGALSKDLEGKLKEVVQSFTKSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P463</accession>
    <name>A0A9Q8P463_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">mRNA cleavage and polyadenylation specificity factor complex subunit pta1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01388</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757116.1">
        <property type="nucleotide sequence ID" value="XM_047900536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P463"/>
    <dbReference type="GeneID" id="71981266"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01388"/>
    <dbReference type="OMA" id="AREMCLN"/>
    <dbReference type="OrthoDB" id="331600at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="5">
        <location>
            <begin position="92"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="743" mass="82991" checksum="5C47BA5C10106AC0" modified="2023-09-13" version="1">MASPAEALQSLNSAREIVLKDHTLYPQVVLGVLQVIAYTAQLEVRRWGADFLAETFASQAVTPDEKQQMAPTVLETLKGWLNRKELMGEDEDTTVVKSAVQCAASVYPFIFRHTVNNTSDSESWSKMATIKSSILRRMDTASPGVRICCIKFVACVVQTQTPGLIADPRRPEQNEISLALVPRDHTVIPPANLEAEASGLLDRLLGVLQDNLSDALIVTATLNSLARLVHRRASISSKILATVLQFNPLRAAGRPMTTKDKLTIKSMTRTTMSFLLNCLKRNPNSAFAGRIQQQIERLKHGLIEVFSENHHLKRPAPEEPVDGLDDAKRQRLDADATNGTNRSQQHIPHTGYPPLPPGPMSLAQLWTLTNDRSVAEFQADRLPIPIIQQLIPAMLNAVPKEKLDEAINAVRSRWLDLTRAPPMPNVPRPVPGDEDDDDYDPTFGLSGENQAVSRLEHLPLGGPTNDVASTFTLPPPAPVNDMERDEYSKTAVTRVFETLKDMDNDIRVKGKPAPAEHSFNRLAAASASGHDREGWVALMIRVATRGSGGNGNGVKGENGERSLAKKGRPFTVSWGIRESLLNYVMEAFRQRIDVAIMWLSEEWYSDRLSIKERQAEGEDVEDDDFPNYWHWTLRTLDAMVPYFDVKDDKVLIRFLSEVPAINEDVLDRVKRLAEDPERIQMSTKTLLYLIMFRPPVRQLAIDCAEQMWKENPDAKPAARKILTKWRPGVLEQEGAAETKTEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P534</accession>
    <name>A0A9Q8P534_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757865.1">
        <property type="nucleotide sequence ID" value="XM_047902672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P534"/>
    <dbReference type="GeneID" id="71983402"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03524"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000080">
        <property type="entry name" value="Aminotransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858:SF1">
        <property type="entry name" value="LD15494P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="76"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="504" mass="55943" checksum="F0C3E53BC2E70562" modified="2023-09-13" version="1">MSTFNLIHLVKHLLWSANTDMSTNYSATPAGLEDEIKPAINLLRGWPSSSLLPVELIKEAANAVLSDTSVAYDGLWYGPDPGYEPARVAIASWLTSFYKPTASISAGRICINGGASQSLACLLSVYTDPEYTRNVWFVSPAYMLAFRVFEDAGFHGDKQRAVPEDEEGIDLEYLRRELEQSEAKAKKEGNTAPRYKPHRERAKVYKHVLYCVPTFSNPSSRTMSLRRRRELVQLAREYDMLVSCDDVYDFLQWPADVSQNQLNGSGTKLEMMKTSHLPRLVDVDRELDGGPERDGADGFGNVCSNGTFSKLLGPGLRCGWVEGAEKFSYGVSQAGAQRSGGAPSHLTSIYISRMLVSGQVQKHISDVLQPAYASRYNTMAKAAKEHLLPLGFSLSQPDRDVVGGYFIWLGLPHEIKAIELTKRCQEAEALIIAPGSIFEVPADDSAKFEHDIRLCFAFEDEPKLREGVRRISVVAKKLLAGAHSTGDYVMVPKAEDEDRLQNFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5E4</accession>
    <name>A0A9Q8P5E4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Target of rapamycin complex subunit LST8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758406.1">
        <property type="nucleotide sequence ID" value="XM_047902450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71983180"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03302"/>
    <dbReference type="OrthoDB" id="10248252at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="905"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="959"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1144"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1395" mass="151454" checksum="784C272F91E2AAEB" modified="2023-09-13" version="1">MSVIDLCSSDEDDEPSPPKSALSSFAPRKEKFTGTGSTSGQNGSVGKADGPQRPQQSHSNNGTPRAQQAQPNVFLPARANGHSVGFVNGSVGDSSYNVSHIPRASEETRQNNSNGERRGSHHNGSPGGASLAALLAGVAANDNASLEQLRSSMGKRGFGSPQAEQRSSGGIDKDQRYKDRRVSQVPVRENAVHKAQPRKSDAQVVLKQPLQRSAAAGPGSGDTSGRPWSGSNPSPISAGKPASIPQRPDFIPRANTSNEDSYSGAGLMTVAAAPGVTGVQQNFKRTVASIDPYQAIEAAIKRRRTDDGANAAQKSFKVTDIDPKTRPSSVDKTDPFGERVSYSDEPDLPAPRPFQRTVTSIPRSAADLPRAVSTVAKSSLDKELEAQIAINAATLRTSDSDHSLSTTRDDAPVVSPAGLVTAATGKRNAPYTIEDRRLLKRLKEVDGLSWDEIISYFPGRSLGSVQVHYSTKVKGQRLEPAQNVPTRPQRIAPPVVRPTVPKQNIRKPSPEQRAAPVRKRGARVGGPSAIDGLVSWASVRNAGREIIESAATAMKDGDMSHPNYLLKQDLIHPNSASRALRMRELGLTGMRAWGTSVRGVTEELKNHVVKSHSIQKQYHGTSGDVVALSWSANDDRFVAGSIAISDATSMQYNMSRNLLIGDAKGGELRELVEHHVHRPLVDNEKNVNGLHAMRETQDPRLFLTVTAAGFSPKGDRLYTAGTDQHLRMYATKKDLSGVTCKYAVPHTASVDLLSVRANSAVATGCHAASSCVKVFNCSRWDFSERISFSPSRSNLDVSVPIYPSALKWGQAHHHSNYLLAGFAGDEEKAHAGETCLWDVTTGQSVDLRTATRNVFDVAWNPFPSSASVAFAVAALSTGTQVSKGTRGVVHLFAPNQQYARRVKTLECRARDLNDVVFCPHDDKLVATGSADGTVYIWDLRASVDVPLHTLNHGSSVLVEDSPDTGVRFLSWGATASRLYSGSSDGIVKVWNPYRSSDNTHIEDIAAPSHQRSAVMSAAFNSDYRELLVGTENGRIDLFSIGGQTRAKPQHFKLHTAPPPRQKRQEPFEAARSLLATGQIELRPCGSMPFRQAVQGPNYSGPFLAPPADETMQAEATYQDALTAQHEASMKSAARMADPGDDEDLLKASKKVHEAQRTIDDLQERLEHFTFAQPKAEQFQRSLLRAEEAHNVLTALAHDTAPCSLECNFLPSADEREDSGRSELRIPGTLRAMDLNAARAKDEELDDACAMCFPRNVLVMNKHPVRIHCASCSLKRANLNTTCSRCSAPARAEIDKTKPTLCERCSFPCFRCGQTANLETNPDGVNVVTCPHCALVWEADVLGYKLVSSTGRGQIRRRLSPEGFPDRIGRHWDGFADDEREHYASLWEETPQDQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5J3</accession>
    <name>A0A9Q8P5J3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758332.1">
        <property type="nucleotide sequence ID" value="XM_047902807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5J3"/>
    <dbReference type="GeneID" id="71983537"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03659"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="21835" checksum="ABD99068843E8F26" modified="2023-09-13" version="1">MTALRLKTSLKRGRGSLDEEDDLDDGGVLVMLTPKPKRASIEAINLEDEDRNIVTNHESLSIPRAAPSAPAFDYQVCMEPHKSYSTKTCDKSKLPKSILEAADRLGAKYNSLSHSSINGSSWSFQAPSACLREKLRKQNTFWRDGNNDSVACQDCARGRMPCFKWTNEGIFLLALHKEDRVEHVAAGAIVEARWVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5R3</accession>
    <name>A0A9Q8P5R3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758542.1">
        <property type="nucleotide sequence ID" value="XM_047901710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5R3"/>
    <dbReference type="GeneID" id="71982440"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02562"/>
    <dbReference type="OrthoDB" id="4886853at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="13816" checksum="A9B8A764D54F49B0" modified="2023-09-13" version="1">MPHDLRTGVEEDHSNRITESDTSAEQRIQLSDERSINHDDHDINGLTKGVEYARTTTSTVLHSNELPSNWNAPDGLGGCTVHKTVFTNTDKTSGKAITKTSLVTTTVKATDGKRKVAELVEVEVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5W4</accession>
    <name>A0A9Q8P5W4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Increased recombination centers protein 22-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02657</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758779.1">
        <property type="nucleotide sequence ID" value="XM_047901805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5W4"/>
    <dbReference type="GeneID" id="71982535"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02657"/>
    <dbReference type="OrthoDB" id="1926781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040301408" evidence="11">
        <location>
            <begin position="22"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="240"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO14413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="33082" checksum="AF8A52148D72BCBC" modified="2023-09-13" version="1">MVSFKLAALAAVALGSLNVLAQDTAADIQVEDNIGDTPQNPAKPDIADVNVEDMQNYLASGGNQQWKTGSSDPKPLNVDVNVSFPDAEIFGVKLVNGRPTRALFHIANNEDTDINVLLGLGALLTPLGTPGAPEVPQVVRNMTGAKFGTVIAPKSKETLTYSFSNVMQPQDLTLELQTVIAKGQNMFTLTVFSESVSIVEAPTSILDPQIIFLYLLLAGIFGGTCYFIYNVWITQLFPQKKRGGKGGERAKRSSGGSKPVDPSEQVAVVGADGPAVTTGSKTYDESWIPASHLQRPQAKRVGSGRPKSRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P679</accession>
    <name>A0A9Q8P679_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07992</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759037.1">
        <property type="nucleotide sequence ID" value="XM_047907140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07992"/>
    <dbReference type="OMA" id="NIGPGPI"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047657">
        <property type="term" value="F:alpha-1,3-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070600">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11323">
        <property type="entry name" value="AmyAc_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000058">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000073">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000052">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040401967" description="alpha-1,3-glucan synthase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="2401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1091"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1968"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2000"/>
            <end position="2019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2026"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2061"/>
            <end position="2081"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2093"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2141"/>
            <end position="2163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2183"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2220"/>
            <end position="2241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2248"/>
            <end position="2267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2299"/>
            <end position="2320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2327"/>
            <end position="2349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2373"/>
            <end position="2393"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="65"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1694"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1749"/>
            <end position="1822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1782"/>
            <end position="1816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2401" mass="269417" checksum="D3AA0413A8017592" modified="2023-09-13" version="1">MGVMGMIASFALCIALGTAYRFDPAYTEINLNQNQTAAHSLDFWGEWTGHNYTASPDNWRFPFYTLFLDRFVNGDPYNDDINGTAFERVTDSNQMRHGGDLQGLVDTLDYIQGMGIKGLYIAGSPFMNQPWQYDSYSPVDLSLLDPHFGSIDMWRVAIDEIHARGMYVVLDNTFATLGDLIGFQGYLNETTPFLLKEHQVLWKSGQQYWDFDIGNEYDESCTYPRFWNETGYPIDQALKDEMKGCFTSDFDQYGDTEAFGVYPDWRRQLSKFASVQDRLREWKPSVREKLENFYCMAIAQLDIDGFRYDKAVQATVDAMADMSAATRVCARRYGKENFFLPGEITGGNSFGSIYLGRGRQPDQLPDNITQAVTLNRNNSDNYSIRDKDGVALDGAAFHYTTYRSLTRFLGMDGNLEAGYDTPKNWVDQWNTFLLTNDMVNANTGVFDPRHMFGVTNQDVFRWPAIDRGIERQLLGHFITVLLMPGIPKLLWGEEQVFHTLDSTNDNYIFGRQPMSTATAWQTHGCYSLDSTQYYHMPWGPARHSCNDDSVSQDHRDPAAPVRNILRHMYQLREAFPVLHDGFFLQQLSNQTWEVQYAGSSGVATETGLWSVMRNSLADVQNLTSIHNGYPNQTEPATPVWLVYTNHNSSQTYQFDCRDNATDLNSTSLIAPFPHGTTVKNLLYPFDEHRLVNSTQFLGISGSTTSNGCLSKLSMKAYDFRAYVPISRWVGPKPMITKFSPGHDARLLTVNADSNGTEDVQVAVEFSVDMECDTITDSISFSSTTAAGLYPYVDRDTVRCDRFNNPADSSSWIGGTPSGFSWSATLRNVSHGVHRMSLDRPHAKKLGPGQTRNVTTEALDHFLFRVGQTDNPMVFTRSANYSTTLLSRASHGQITLNHSAAGADLFRYSTDFGASFSVWAPYQHGLHQVSAYPTGSSDRKTWNGEHVRVEYFSRLAGSSSHVQQGDLHAKARRFPHMYLNGPYNAYGYDAGLDNKMKLTEDYTWEFTWNREWSNNGTIAQINVWGMGPDGKPDSTKVLGDIDGDSVLDQLPPSSLAKLVLNVTAPPPKPFLAWKFIINDGNLRFRVEPTGSMWWQLALYVVLWISPIIMAVVSTWVFVGSFYKIKFNKFGVSEKLGLLGLLPKSLRKLLRGNSDEANSGLLARLKHGSRIFSRGSQIWSRRGDAIQAQSDSRRTVLIATMEYDIEDWHIKIKIGGLGVMAQLMGKNLEHQDLIWVVPCVGGIEYPQDELAMPMTVAVMGKVYDVNVQYHKLRNITYVLLDAPIFRQQTKAEPYPARMDDLDSAIYYSAWNQCIAQALVRFPIDLYHINDYHGTVAPLYILPRTIPVCLSLHNAEFQGLWPMRNRKERDEVCSVFNLPPDIVSEYVQYGEIFNLLHAGASYLRIQQEGFGAVGVSKKYGARAYTRYPIFWGLKEVQALQNPDPSDTAVWDKKLPAETDIRIDEDFEKTRLEERTQAQEWAGLEKNPNAELFVFVGRWSMQKGIDLIADAFPAILESHPNSQLITVGPVIDLFGKFAALKFEKLMELYPNRVCSKPVFTALPPFIFSGAEFALIPSRDEPFGLVAVEFGRKGALGVGARVGGLGQMPGWWYTVESTTTAHLLHQFKDAIRGALSSSTKTRALMRARSAKQRFPVQQWVEELEVLQSTAIRTHDKVAAEKNSWSSSIITLVHPHPSIHPTLGSGAKQTPRGSMYGPSHYSWDGSQVQTVEENDVIVGDREPLPPMATEIVRELRHKSHPFPGLRGDHEEEEEEGDDRSICSIHTPARSSSPVQPASPITTKSPHNSTNRSSMTNVQTARSSMAHPYASTARTSVIPRSVSGLSMQNIVGEKTDFNLQNVDPFFTDNNGHFYRAFSKKLDTLNAANSESTNCIEEFLAKSEKEWFTEFRNAKLGMLKRDGTTTRPVSIAPSEPATADSSSEKSHIQVNEFMLRDEYKPPTGLRKWMQVRIGSWPLYAYFMALGQIIAANSYQITLLTGEVGQTATKLYIVASIYLVASMLWWLCFRRFASYVSLSLPFLFYGTAFFLVGIAHFAPTVDGRGWVQNVGTGFYTLASASGALFFALNFGDEGGAPVKSWVFRACVIQGSQQIYVVALWYWGSFLAKHRALGYEASQDSVVGTWKVTAITLPIAAFLWIICLVMWLGLPSYYRQAPGKMPSFYRSIARRKVVLWFFVTALVQNFFLSAPYGRNWSFLFSSIHVPAWQVLLLVVLFFVIVWAMFCGLFAYLSRSHSWILPLFAIGLGAPRWAQIWWGTSNIGNWLPWAPGSIETGAIYISSALLSRSLWLWLGVLDAVQGVGLGMIMLGTLTRTHVAFAITATQVLGSVATMLGRAVAPNRLGPGPISPDISGGLSTGLGQAWFWAGLLANLALCIGFYKFYRKEQLQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Y5</accession>
    <name>A0A9Q8P6Y5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759874.1">
        <property type="nucleotide sequence ID" value="XM_047907644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Y5"/>
    <dbReference type="GeneID" id="71988374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08496"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="421"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="502"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="601"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="691"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="827"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="933"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="964" mass="108054" checksum="08200F76BB07042D" modified="2023-09-13" version="1">MVRSYRKYESGQSFGTVCTATSNTIWTPDGSSRNAGSGRAFVGANEDVLCWDVKKGELLSRWHDKDNRSQVTCISQCEVQPDLLAVGYTDGSIRIWDALSGQVVVSFNGHRSAITQLQFDQEGSRLASGSRDTDIIIWNLLSETADFRLRGHKDQITGISFLRTQITPRDEQDGAVDEANVSETEERYLLSTSKDALVKVWDLSTPHCIETHVAQTSGECWALGISPDGAGCITAGNDGELKVWRLDLEALAKLSSNVGDGKKQDVLVSQGIIHRQSKDRTIGISFHARQDYISIHGSEKAVELWRIRSTEEIHRHMQRKRRRRREKAAAAGEALVPEKEEALEPPDVSDVFVPYVIVRTGGKLRSANWITSGNKSVKHLQLLTATTNNQLEAYNVISHRAQEKTGSREAPDYSRSLAVELPGHRTDVRTLALSSDDRMLASASAGALKVWNLRTQSCLRTLECGQALCSAFLPGDRMVLLGTKTGELELYDISTSTLVEKIEAHEGAIWTLAVHPDGRSVVTGSADKTAKFWRFDVVDEDIPGTRRTTQRLKLTQTRQLKVADDVLSLCFSPDQKYLALSTLDNTVKLFFVDSLKPYHILYGHKLPVLNVSISSDSKLIATCSADKNVRIWGMDFGDCHKAFFAHQDSVMQVGFIMHPVEQDERHIVFSASKDGVVKTWDGDKFEQIQKLEGHHGEIWAMALSRTGETVITASHDKSIRTWQVGDDLIFLEEERERELEEMYESTLAQNIDRDLQDGDEQDAEVAAASKQTITTLIHGEKIIEALEVGITDLHLMRAYERDKVHNPKLAVPQDRNPIFQYSNMSAEQHVLQTLRKVPSPALNDALLVIPFSTLPTLFTFLAVLLQKHMQPELAWRITYFMLQAHMTQIVASKQLKSILTDVYEAYEAWQEEERKVMGFNLAGLEIMSREVRENESSGYLDEPIDEDRDAMEKGRKKRAFASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P720</accession>
    <name>A0A9Q8P720_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07917</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759922.1">
        <property type="nucleotide sequence ID" value="XM_047907065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P720"/>
    <dbReference type="GeneID" id="71987795"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07917"/>
    <dbReference type="OMA" id="HIILHIV"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="17043" checksum="1CC82673A64E2A59" modified="2023-09-13" version="1">MPPRKSPNAIAFPAKVIDRSTSAQPIKSTSTTASSSQQPAIRSLQDAQNILINVWNNYVAQTPQRTKLLDAFLAFLAVVGALQFVYCVIAGNYPFNAFLSGFSACVGQFVLTVSLRIQTNPNNKADFESISHERAFADFVFGSMILHFFCVNFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7J7</accession>
    <name>A0A9Q8P7J7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760581.1">
        <property type="nucleotide sequence ID" value="XM_047904409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7J7"/>
    <dbReference type="GeneID" id="71985139"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05261"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="30495" checksum="79AC270DC2EEF1DE" modified="2023-09-13" version="1">MPPGGPKARPSRVTRRSHSDTGEGSVFGAALIIGKVAQARSHYRTALDIDNATHPPDPTDPLLAFVIEALAQCCDHFDQNNEARKLFLEADQRFGRTAAKSDCIARNLIEYSEFLYKLQEYQEVIRILEQIWPDIVSWWPAEHTNSIRTADLLALCYLNVGRPSHAEKLLESVIENWEQSRNYDLEVILAVRLTLHRARVALGKEKPGTAFRNSRAVYGVTEDERSHRDPCLSRPRLQTSTVAVSAADSLSLHRWAWVCNDGRGDVGIRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7M0</accession>
    <name>A0A9Q8P7M0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760534.1">
        <property type="nucleotide sequence ID" value="XM_047903856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7M0"/>
    <dbReference type="GeneID" id="71984586"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04708"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="24748" checksum="D30B8521741655B3" modified="2023-09-13" version="1">MPETRRASHQSKVQWLEEYQKAALVNKALGAGQEAERMRRTTHNRNSRFFQLSGEIRNRIYELTFSRRTPVNSSSRLFWHFPGLVEACRQSYIEGLDIWYSCTDFYVRDTPRLPSWLRSLSVEKANLITSIHHTGVKKSGRHATYTGQQFLDRMARLRVEMASEGIIIGEGVIKAPVDIGRMVWTSSPDRHRRMPTWDWNMTDDLTDEDDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7Z6</accession>
    <name>A0A9Q8P7Z6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_05092</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761031.1">
        <property type="nucleotide sequence ID" value="XM_047904240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7Z6"/>
    <dbReference type="GeneID" id="71984970"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05092"/>
    <dbReference type="OMA" id="KMINYRM"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000047">
        <property type="entry name" value="Small nuclear ribonucleoprotein SmB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="146"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO16665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="20450" checksum="0FE5BED653A9B3B1" modified="2023-09-13" version="1">MASQKQGKMQGYINYRMRATMTDGRQLVGQMLAFDKHMNLVLSECEEFRKVKRKTKQGGAPGAQSGAQVIETEEKRMLGLAIVRGATIVSCAVDGPPPADPAARLGQSAPGGAPAAVAAGPGIAKPAGRGAGIGLQGPAAGVGGPGFPGAGFPGAPPAGFPGRGGPPAGFPPAGFPPGGGPPGFGGPPPGFQPPGGRGFGAPPGGFPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8N5</accession>
    <name>A0A9Q8P8N5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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            <begin position="20"/>
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    </evidence>
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</entry>
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    </feature>
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            <end position="48"/>
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        <location>
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            <end position="85"/>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
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    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="25364" checksum="6B2AD1243BB3EAD1" modified="2023-09-13" version="1">MHWPVADKLFGGKEINYRDAWSGMVLLKQKGKTRHIGVSNFSPEQLEDLLNHTSTPPEVHQMELHPYLQQNEWIDFHKTHSIHVTAYSPLGGTNPAYDKKSKDKKNKKDKHDDPTPLLKSKVIHKIAKKRDCTPAQVVLQWGLLRGTSVIPKSVHKNYIKENFKATEFSLKEKDIEKIDKLGKYHHRYNNPSGSWEVPLYEGLEDQDGEHKGAKFWHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA89</accession>
    <name>A0A9Q8PA89_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763114.1">
        <property type="nucleotide sequence ID" value="XM_047906093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA89"/>
    <dbReference type="GeneID" id="71986823"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06945"/>
    <dbReference type="OrthoDB" id="8964540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040421524" evidence="2">
        <location>
            <begin position="21"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="762" mass="78997" checksum="97DDAA855F5F52F7" modified="2023-09-13" version="1">MLLSQLVVLGAAVSNYGASASAVRMPIFHRTGWGNGTGYANATGYANATGYANATGYANATGYANATGYANATGYAHATGYSNATYPAISATGGFSWPSPTPATPAEPYLNQTMPVDFNGTAASCDAGCRDEFKNRTLLANAASAATLVLDRLDLWKECWEEPRCQNAVAMMVGSTATALFDTDEEVCTGSWDDRCFADWMITVGNKAALQSMAGTYSVLKTLVANATAGDILSPSEQKLLWDMGQLSAFINSGPMVDPNTFTAQMQNTTVNSTAIPDWLAATPAQTTQSTETFPSSTQAHPRTTRTPAYDDSDKDDDAKKYAPLALLAVAVPALGAGMWYFGANHGFTKLGNLIRPFRSSGGSFVQRLTTAYNTQMAGKGGFRSAYKNAEYSYELGKPPPNDFTRRTQPYRLSRAPKMPTTGSEWKAKPNTPEVTEVWPWEEPSVPINSPCESPVGLRRRAAGGCLQEPWTGADSAIATGYDAVMGAMPVAQQVIGTAAGLGSVMLGGVDPFGGFLSLIGHGGGDGSDDGGNDDKPTHHPKPTHKPTDQPKSKHDEATSTTSDKQHESSSTSPESKATSTSLSPTSQTTSTSSLSSSLASTTSSSLLSSSASTSSSTSLSNSTSTAPSIWNPFAAPSPTATSSTPSSLWSPSIITLVSAPSTTPTNLITILTSTPAATPTNVLTIGGGPAATETLVAQLGEPAWAIVPVSLIPVGSVVPNGEVAVGTYDSSVMVAASSAFPKGLDMNAVTSVLGPLPTGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAI2</accession>
    <name>A0A9Q8PAI2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Meiosis-specific serine/threonine-protein kinase mek1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06821</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763284.1">
        <property type="nucleotide sequence ID" value="XM_047905969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAI2"/>
    <dbReference type="GeneID" id="71986699"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06821"/>
    <dbReference type="OMA" id="EDQYTIT"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="157"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="67383" checksum="9B74C037F3211939" modified="2023-09-13" version="1">MAVSRGDTSVACFVFRTATHPDQEVTMHVYPNDEFNLGRERLQDALGIEDRCLSSHHFHVRCVVYDDDDEHKIAPLVYFRILSGNMAILRRNGLHDDPDDGIDVGRSSGDILLNFGDSLQLTSQVSVEFCSIEGQSFAPPPLNKVQRAEIKLIQEYRLTTKVLGVGGYAAVYVSEKADTGQQFACKIVAHPAEKTADAAQQKERQKVAREYTILAKLSHPNIISLEKVFRATHHDYIFQELITGGDLLSYMDKKGHLTEPQGAVIVRQLLEAVKYLHDHRVVHRDIKPENILVTSWRDGARIVLTDFGQARTMDDVEHAVKKAGIFRMQTLVGTIGYTAPEVYAQLRNDLQQSAGYSQAVDIWSIGCVAGTVLTGELTFPDDAQLRAGIVDVSRFTKHLENIENGSEWERIGHRAKSFVKSCLATEESKRLSAAECLDLPWFQHPHYKRQFDALYQRAIADWKPRVQEEDLTETIDTTDQNDESEGHGETQSRFFTRSRSQQDDMLARFRPNELCASPVQVPETPPRRRAESSGIALEESQFIDLGDFTMPPQTATYDDDIDQNLDLATQNLTRNSLLTADRQPWHVTASKRKAVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAN3</accession>
    <name>A0A9Q8PAN3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase/reductase ascJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763339.1">
        <property type="nucleotide sequence ID" value="XM_047905797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAN3"/>
    <dbReference type="GeneID" id="71986527"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06649"/>
    <dbReference type="OMA" id="DYSTAKH"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF11">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="32011" checksum="F4FA47E665760E81" modified="2023-09-13" version="1">MTQFHITDSDLLPLQDKIVVVTGGSSGIGLASINVLLANGAHVVSGDMNDPPTQHAHLTFQKTNVTSWDQLKSLFSLAISKHHRIDHVFSNAGISGRADYLASDYDDAGELLEPTSQVYDINLRGMINTSYLALHHFQHQSPPGGSIVCTASGSSFQPFAVWDYTTTKHGVLGFMRGALPNLALHSLPIRINCIGPSWTITGLVPKEIIDAAGIESQPASVVGRNVAYLMADESRNGEFSYSSGGRYYEIEKSCLLPAAAKACGVAEVTVNEQEAFERISKLAVEAGIKEGQAAKGEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB78</accession>
    <name>A0A9Q8PB78_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763633.1">
        <property type="nucleotide sequence ID" value="XM_047906232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB78"/>
    <dbReference type="GeneID" id="71986962"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07084"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="41969" checksum="6C78C7422CE37838" modified="2023-09-13" version="1">MDHDTDDEWDPPSDAEEQFFDDGYCPEAMQVANADEISGNRPVIKTDMDRPCAKVFSMPELMENILLMVADAAVDGANASSTPRLEPIQTLTGLPRVSSDFFQAMKTTKLARSIRSWQHENQEVVADRGKFMQICQLVGVENEYNTIAAINYSTAPRLDLTFSPGPKVEAKHARCPVFWLFQHLIEKKNPQYRIDADAGSTGILSGGISSGGTHTAPLYPPVLAAYYTANSPEDDDDEEEDEEDKIRVDPMPGTLAITIPKFYLNTNSLQGPTRMLNTFLKSNMAGEKATWRNIQAVNGDKLTISFDNVSARYDGSSKRLHYKVRLTFDRDATLGEVFQQYHDFVKRSREEHWKLSQHKDARIHGYTHPAFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBP9</accession>
    <name>A0A9Q8PBP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763901.1">
        <property type="nucleotide sequence ID" value="XM_047906020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBP9"/>
    <dbReference type="GeneID" id="71986750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06872"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="16867" checksum="41C5E3E41F6EAA69" modified="2023-09-13" version="1">MDKGNTEAIRIHAEKVSQQATTTMLPHLEQLVKLADMFFHLSVDGKPGLTKFTENLTNVVDKCLRLKINLCRSSFSHAFYWPAPRQPIDLNTMNCPYQQICSQPSVVAYTLLPGILITEHSEERIARSADVMARAADLAVNLAPLGSPMSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCI2</accession>
    <name>A0A9Q8PCI2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 9b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764243.1">
        <property type="nucleotide sequence ID" value="XM_047909190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCI2"/>
    <dbReference type="GeneID" id="71989920"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10042"/>
    <dbReference type="OrthoDB" id="10264848at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="251"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="782" mass="84721" checksum="D971824C22061AF6" modified="2023-09-13" version="1">MTDSLPLTTAMSTDNRPRPLHASRSFTRMDNFPEPELSPRKRASTLQGNGIPAVPAARQTATSPELAGKKPMADVFENNEDDEHAGSHIEAAKPALNVPSTFDELPIEIKVHCERFLERLSAKVHPTPLSADDLSDLFQQFYDRAAGHISTHIAILASRIGRETPPASSASSSSKKQLGRPRAGSGARKGSTTLDDSATGGEMLTASEVSDRKRARKLLEHKKIALEEAVERGVCEKVYEKIWKHRSTDDDARDEKLRSRTAALSLVGIGLKELHMDTTDQAKADVRKTAEEKEEEINQSLSAAREALIRMDDDHYPLGKLEHLKAAHKAIVETLTQHFPSSSSADEILPTLIYTLITSPPEGTNVVSNLNFIQRFRTSSKVDGEAAYCLVNLEAAISFLETVDLSSLREDELPEGPAKAQSQNSGSRPSTPTLDKAPVEVTPRPTVARTLTPGLSPATAISSDQSTPDSSSATSMKAALPSPGIQKRPQLHQRRISGLIQSNIDRIEAGRDNFLNSADKLYESVNGTLDDSMKFLFGRFKEQVGNGSSMMPKTLEDAKKLVSTPPNEQEDSLSISGHSSPGVDDPLNSNSKPADNKVLDLIGGRKQPRDRSVDSSKSGESVRRTVTWDSKSTTKAAEPTTLQGNLFANINPLNQLNKFGMPSFPRFGRAGTVGSSAQPAQSTAAENSAQNAKLSDIVESSATMKDGDSAAALQRTNTKESVAMGDDDMNAREALATLKKIPPPKKRFLEVESAHELKVGEIHALLMDYRRLSKAIGDAVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCL3</accession>
    <name>A0A9Q8PCL3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764435.1">
        <property type="nucleotide sequence ID" value="XM_047909276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCL3"/>
    <dbReference type="GeneID" id="71990006"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10128"/>
    <dbReference type="OMA" id="LWHEKAF"/>
    <dbReference type="OrthoDB" id="429520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="20308" checksum="DEBA4EC45185BF85" modified="2023-09-13" version="1">MAQINWRSINVDALDPESSYNFDLTTLTPAIEPISTADVQTLAGQIRQLSRGGNAEGALRGALENPPYGADDQGKQLHLQTVIEILQSIRQAEMTPILQRIYQSEGGSEVCDTLMKYLYKGMAQGQPSSTGARNVTPQPTGFSQVGGRNFGGGEGGGQAMSVLLSWHEKLVEMAGPGSIVRVMSDRRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCN7</accession>
    <name>A0A9Q8PCN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764377.1">
        <property type="nucleotide sequence ID" value="XM_047909738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCN7"/>
    <dbReference type="GeneID" id="71990468"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10590"/>
    <dbReference type="OrthoDB" id="3637222at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="243" mass="26225" checksum="DF88417976E9F9DB" modified="2023-09-13" version="1">MSIIERSAPINLQYRICVVTSASSPLGVVISKTLLKANAFVLGVDTQPIDPSLNAGLGTHFQFEQRDVQDVQTPKQLIEAVKEKFGLENIDALVNTVGKQSEVIGLGELSRAIGQVMAEQRKGTIVNVPGDVEGKDEEQHRRVLDLTQDVARELGSGDIRCNAVVLQAPTNAGQHQSAKAYEEAKTHMKTLMNTEKVKDAPGSTRAAPMMYDVGNVTLFLAGDMSSNIRSSAVLTDGSYTELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK0</accession>
    <name>A0A9Q8PDK0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_10395</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764841.1">
        <property type="nucleotide sequence ID" value="XM_047909543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDK0"/>
    <dbReference type="GeneID" id="71990273"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10395"/>
    <dbReference type="OMA" id="DHDQRMK"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.170:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="12">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00066213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="364" mass="39720" checksum="C326D5165F2112A8" modified="2023-09-13" version="1">MAQVLSPGAVPEPVRQLPKEEEWRENLSVRLTCKDCRTDPPELYEDHASGDLICAECGLVLQERGIDTSSEWRTFSNDDQGNDDPSRVGDGPNALLNGAQLNTSIAFGDGGMRSKELHRAQNKANLDKGNKSLLVAYKQIGALCDGWELPNSVSDTAKHLYKDADESRVFKGKSQEALIAGCVFLACRRNNVPRSFREVMELTKVSKKEIGRTFKMLETYLMSKEKERQANGGNTGMLPGGTVVFNEGYKGSTTSDPSEMCARWCSQLNMSQHASNVAIEIASNMTKSGALAGRSPLSAAAACIYMAGHLMDEIKSAKEVQSVAKVSDSTIRHAYKLLWTDRAKLITDDIVARGANTSKLPKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEH3</accession>
    <name>A0A9Q8PEH3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765349.1">
        <property type="nucleotide sequence ID" value="XM_047910655.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11507"/>
    <dbReference type="OrthoDB" id="160645at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040345551" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="51"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1198"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1319"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1767"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="779"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1332"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1449"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1603"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1616"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1651"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1770"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1805"/>
            <end position="1824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1874" mass="190844" checksum="CF6D702CF786A8AE" modified="2023-09-13" version="1">MARFPIDACRLAGIAVTLITTASAQNPPPPAYMASCPTPATTAPFTVRDECGMDYQISCGRNTGGTQDIDSGVYADTFNYCFQRCSANTECTSFTFQTESKRCYIKRLGSQNTWIAGNVYDISAIQILPRTGSPGACVPKPERNQILTTDDPAPVCPDNTDTLYNSANGNQYRLRCDTGFVNAGSYMMPPGNRGSFTACINSCTDAIQCSGISFAGFARPQDQGQGDCYRFTSANTGALVRGGGNVVAVRQSPAIVVPPAAVSTTTTTGTWTATTTLSTTFANSYAPSPTNVVVIGVPYPTTTSTLAGGYTTTETLTTIAGSDATPTATVVEGVPYSLPYIEFTGETLTGICPAGAGNTYRSAGQLYQISCDGAWANNIEDTGVSGQTVDQCLASCGANPQCGAATFSPGMDTGTSTGTCYLQTLTTYYERQLDDATDGNIAIRKIPGDILTQPVVTVSSTLIGDYSTRTTIMTITGGPGPSPSNTEVFGTPYSSPAATVTTLATACPQSAGSVYRDAGQLYQISCGGDFANDLQPATPGLNILYDQDLQDCITACTNRADCGAATLAGSTCVLKSLDTYYYRQEDTATEDNIAVRKIAGNVFTTTITASTTTTSDTSSSDTSTLSTLTGAYAATTTLTFPGTQVPPTPTTYIGVPNPAPTATIVPPSLPCPANPGQYYRSADGQLYQISCGGDYARDETPLPVPGIDLDACVALCDASDTCGAAVFDPRIGGACYRKLLNTYYYRQEDPDTASNVALRKVVGDRVTTTATTATTATAVVETSSDGDPATTTDTASGTSTSSTASTSSGAARATISAPASPCPNNVGQVYRSEDDVLWEISCDNDFTGYTDTNIATADSNIEACLALCEVTPGCGAAVFNTQNVHCYLKPENAPSTPPGEETAIGNVGFVRLEDQGDIPEDPNADVEIEDPTLPCPDYDGAIYRSEGGEEYRITCDSDFAFQGTSLGYGLILRNLGLEACLAECENNAGCGGAVLLAPDCFLKPPDTYLTRVGTAEGSVALRKISGPAVASSVSSATSEPTATSTTESASTLTDSVTSISSAISAPTPNPCPRGADGTVVLPYVDSFGDAYQVFCGGAAEYNQDLTQLNDLTNLDACMVACDTTLRCNAVSWIGGNSGAGQCTLKQGATQDGAVSDEMFVAVRVNGPVDSVPALSTSTEAATGTTATATSSTASINTDDVLTSSSTTSSATTSPTSSQCPEPLEDVCANEQNELGVITCIISDEYNELYSYNCGNTITGPTIPTDEVSPDPYGQVPDVVDLAGCNLLCERNRPRCKAVNFYPATGTCILVETPDGYEITPGAISCEQENSDSDGSTSSSTSGPTAPPYDSTATGGTASATSSQTDSATISTESSAPTASSSATESASSVSSTGTGTSSIPSAGSSSGGSSATGSMASQYPGGSSEASVATDSTTSSVFEATSSPTTDLSGTIFGSSSSSQSPYIIPTISTGSTTSSDLKVTSSPTTDLSGTISGSLSLSLPTDYFPGGPSQSDATTISTGVTQSLSTLSTDVSSAPSDGPPASEYPPPGGSSQTTGSSSSGGSVSTITVSIPSGSIMSVSSTTSTGTASATSGSEIPTGYENGSASGSSSTSSGSQQIPINYNTGSFTSTGPPLTGSNPASYPGGNGNGATSGSSTSTTTSGPAPYVSVCPAYDGQYFTAPAYGSSQYLVDCDSAYTGDEIINPIQYRQLSYSPQQGSCMATCDKMINCVAINVAPEGCQYFSRVNETLTISPGTIALLKTEQGTIPEYPGGVSTPPGSQTPTSPGTYPPGVSVTPSTPGGGSTPPGSIGTGTPATTPGGNETPPVYPPGSSGGSRTSTVNIVTVTVCSAQTTRTTTLFTTNTVTTCAAQGCPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF51</accession>
    <name>A0A9Q8PF51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765694.1">
        <property type="nucleotide sequence ID" value="XM_047910422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF51"/>
    <dbReference type="GeneID" id="71991152"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11274"/>
    <dbReference type="OMA" id="ARWGHEG"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="389"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="677" mass="74810" checksum="5FB25942877E12BC" modified="2023-09-13" version="1">MSSDLSRRSSRQPLNDDATSLTSFPDPAETTSPSLEPLDEPPDAVAGGQLTGVSPPLQPVKEQIVPTAPAHYGLNGLLDDAGPSMFDEQENGVGDPQTLSTASTEALRRIIDHRGAVELVRNLSLLLAERDAHVTALTRLAEEFKVPRERIAETGNRVKQFERRRLSLAGASEDLAPTIRSESSDSAAQASLPDVGRGTIRNLTRMFGGGGKRKDATIRPTPASMKSAATSMKSTASASSSRSNSIVPESTVVRKRTDRPKSIDVLSVNSGESTGWTSTFMNAGAGTIKGISSLATRERRDSRAKEPRGPVEMSTRHDKNQLPPTLLRTESKDPREMAWNKFVLRLNELREEAGEEAQSGEVLGAARWGHEGGNGKQKLDTLTRLVIGGIPMRLRSPIWMELSNTYAIMRPNGYKYYLGTQENEDPQEIDAILKDVPRTLTSKYDYFAEKGHDRLRKVLVAFVNKYPGLGYTQGLNMIAGYLLLAIPDESDAFWVLCNMVDSYFPPDYFSPDTAMSAPIADNVVLRQYVKDLLPKLYDKMSSLEIEPEHTVPLSWFLTAFASVLPESVLLRIWDVWLCVPNSKTFLFNVALTLLAAHAKNLMSCEDQGEYWAYMTSKIRVGEEPDKVNELIRSAFGLRKRLEQVEMRRGLAVKKVRKHASTEALFSPEAQGEEEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF73</accession>
    <name>A0A9Q8PF73_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765685.1">
        <property type="nucleotide sequence ID" value="XM_047910163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF73"/>
    <dbReference type="GeneID" id="71990893"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11015"/>
    <dbReference type="OMA" id="IFYANTT"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="19943" checksum="7FD0266399404A0A" modified="2023-09-13" version="1">MAKVDVEESPLLRLPPELRNRIYHELLANTPGIFHLNEENMAHPILNTNRQLRSECTGIFYANTTLQFSSPAVCTRRLTTLDPKIVDLIPELRYDTSETCTKAMSWRTAFRELPGLDEDTKLENLKDELKREGVALRLGVLKARICIAGGPSWTSDPLAAALDAVKQGVMVSRMMFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG30</accession>
    <name>A0A9Q8PG30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766136.1">
        <property type="nucleotide sequence ID" value="XM_047908148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG30"/>
    <dbReference type="GeneID" id="71988878"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09000"/>
    <dbReference type="OrthoDB" id="3624217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="17657" checksum="F6ACE9B93F0297F4" modified="2023-09-13" version="1">MPSELTQKPKVTDKSFSSTAAYLEYLSTTVMESHALTDMSILRDYLAPDFEMVDETIHNCPVPPSSNLEDHLRNTAIFKKQNPGWRVFICNVNCSMVKGANTAEVWMTCRGCDNPDDSMFNRESVSVLHWRRRREDGGWVCYRHSGIRGGGDFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG37</accession>
    <name>A0A9Q8PG37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_09002</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766138.1">
        <property type="nucleotide sequence ID" value="XM_047908150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG37"/>
    <dbReference type="GeneID" id="71988880"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09002"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000013">
        <property type="entry name" value="Coatomer subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="14">
        <location>
            <begin position="99"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO21772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="250" mass="27770" checksum="EBCAB4A10C84EF66" modified="2023-09-13" version="1">MQHMLEASTELPPPRTSTTSCPLNDHIHHSHHTQYPHTTRPDTAPPQTATMAPNMSLFSVNAILILSTDDSSRILAKYYSPPHIPSTAVGNDYPGANPYPNLKDQKAFEKGLLEKTAKTTSDVILYDNRVVVFKTEADTMLYVVGGADENEIMLYNVILALRDSLNILLKNSVDKRTLIENYDLASLCIDEIVDDGIILETDPVIVASRVSRPPQQDIPNMQGIDLSEEGLLKLYSFGKQKLGERLRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGJ3</accession>
    <name>A0A9Q8PGJ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766375.1">
        <property type="nucleotide sequence ID" value="XM_047908880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGJ3"/>
    <dbReference type="GeneID" id="71989610"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09732"/>
    <dbReference type="OMA" id="YWVDQSA"/>
    <dbReference type="OrthoDB" id="9997027at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd03398">
        <property type="entry name" value="PAP2_haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.606.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052559">
        <property type="entry name" value="V-haloperoxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599">
        <property type="entry name" value="PEROXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599:SF1">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE TYPE 2_HALOPEROXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040429372" description="Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38408" checksum="C546BDDBCECEF782" modified="2023-09-13" version="1">MKLSNVLTLLGVACAQAEYAGDIVHYWVSASGSLANNTLIGGLQSPPPGWFEAVVQASMYAAALESKHEDLAFQQLAVSHAAHNSLTWIFHGTRNFANIFTFMQNATRDIGISESDKSYGKAAKIGQKAALKVTNARQDDRLNNFVNYIYGPMEPGVYQRTPGGLTAPDTPQARYLRTFGGLGDVTRFRAPAPPAVNSSGYEEILNYVKAKGEQNSTARTALETETAYFWRESSPIQWNRLAINVVGNKYSKDVVKSAKFFAQVNYALANAAIAGWDSKSFWDSWRPVTAIRRTDVWLPSGNNVSMPTWTPLLSPTPNHQEYTSTHACFGAAAAAVIKIWNNNQDTIDVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGK2</accession>
    <name>A0A9Q8PGK2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_09284</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766402.1">
        <property type="nucleotide sequence ID" value="XM_047908432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGK2"/>
    <dbReference type="GeneID" id="71989162"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09284"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099128">
        <property type="term" value="C:mitochondrial [2Fe-2S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="15">
        <location>
            <begin position="60"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO22036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="16034" checksum="DEB69D4A4FE896A4" modified="2023-09-13" version="1">MFRTAIVRSARLAATQAARPAVRTFAVRSNPFINTSRISTPATTLSAVRCYASSSGLGQEEVTGRILDLLKNFDKVSDASKLSAQAHFTNDLGLDSLDTVEVVMAIEEEFSIEIPDKEADAIHSVNQAVDYIMKQPDGVYYPVPPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHV8</accession>
    <name>A0A9Q8PHV8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767109.1">
        <property type="nucleotide sequence ID" value="XM_047911588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHV8"/>
    <dbReference type="GeneID" id="71992318"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12440"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18314" checksum="53CE69FF1FA50EE0" modified="2023-09-13" version="1">MASVTYLTITQPSPNHYRITEHPTRAQDMTSVSETTSKSFLQRKFSDITPATTTECGPGTIAFTWNGGPIETTGLVYTESLQISFELIFNEEELGSRIVGAFEGNLEQGVKVELFDARGARMMRLEVEIRDGKYIHADAERGRWAKKRVVCILPTRPQSRTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI93</accession>
    <name>A0A9Q8PI93_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_11991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767273.1">
        <property type="nucleotide sequence ID" value="XM_047911139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI93"/>
    <dbReference type="GeneID" id="71991869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11991"/>
    <dbReference type="OMA" id="VDTRDKH"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000163">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000128">
        <property type="entry name" value="Serine/threonine-protein kinase ksg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="306"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="610"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="865"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="865"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="875"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO22907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="894" mass="97281" checksum="B47A55BADBB74CA4" modified="2023-09-13" version="1">MNADLSLSQSLGGLRIANPDDHDDSEALTSPTSPTTPNARPPPPSSHSSESTVTDARRTNLLPTLSHETDSQDSGLGFDPDSYSLQTSNPSPPPPSRSPNTQQGEFADRRLSHRTSMTLNPQAQQPPQPGQYQSHPSGYNVPYRQPSVQGAGSRPISGMYTQMNNSSSSGMSSHPQYRYRDDMGSSDGNMGGLARSGSRGARQLMGSVPQRGDSRTYRQPGTPMSRGNGNGPLPPRRNSRRGRAPTGSSTSTGGYDSAEQPYSGSAPMPRSAEDWRERGAAVGTQREVDASGQTQSRTVKKGVKDFNFGRTLGEGSYSTVLAATDRQNLKEYAIKVLDKRHIIKEKKVKYVNIERDTLNRLTEHPGVVRLYYTFQDERSLYFVLDVASGGELLGVLKKMGTFDVECTRFYSAEILDSIAYMHSRGIIHRDLKPENVLLDKDMHVKITDFGTAKILPDPRPGQNTAGGSSGAPTDGAETDRAVSFVGTAEYVSPELLRDKNACKSSDLWAFGCIVYQLLAGRPPFKAANEYLTFQKILALDYTFPDGFPEVARDLIERLLVLEPANRLPIEHIKNHRFFEGVQWGKSLWKQNAPRLKPYVPPAPEPIKLNGGVKNNGSSNALASAGAAAAMQTASGPPQQAPARRPNLQNVTELPPPSQLDIDWSPVLTHNNERILKLGNLVVTTAPLASSPSSKHGDPQTPSEKPKFSRFFSSNTMRKRERLVLITSSARLVVAAAGGNEKKAKLEINLTANASTCKSSVDAKGLTYWSIDTRDKHYTFEDPRATTSDPAGSRYSTQEWLDAVQQAQEVALATSVTNSYSGESMLNDVTASAVSSPADSLGGDAILPMSGPSAGERHNLRHTLRKNTEDESLKGRDKRHRFSKRNSKSGLAAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIH5</accession>
    <name>A0A9Q8PIH5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767481.1">
        <property type="nucleotide sequence ID" value="XM_047911196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIH5"/>
    <dbReference type="GeneID" id="71991926"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12048"/>
    <dbReference type="OrthoDB" id="3935453at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="31660" checksum="FAD4A3686187CEE3" modified="2023-09-13" version="1">MSNVDLGPNNDLGPGPIASTDARPTSILADDSVSRAGMDAIVSAIGDGAAAAVTTRPGQPTAANALSVLLSALPSDVRSSMVSQFEATQTFSTSTRPTSTSTRPTASSTTQITTPSARSSTHTHASSTSSSIPAATTTAAPPVDSQQISNGTIAGVATGVVAGAVLIILGIILLIRRRRQGQAPFGPRGSQRSKGSGRAYPEVAWLYDPAPTPPNEPSPHREESDASLLPRAPEMTAAGGASPHLRPVGPDSPLLPPHMPFAPGASPVTSPNSSRNSSPRSAGRRSGRSSINSSDPRRPLHIISEETHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PII4</accession>
    <name>A0A9Q8PII4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767439.1">
        <property type="nucleotide sequence ID" value="XM_047910874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PII4"/>
    <dbReference type="GeneID" id="71991604"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11726"/>
    <dbReference type="OrthoDB" id="3650757at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12531" checksum="49BDAC6D7F2DC762" modified="2023-09-13" version="1">MSNPTPPATALLLSLPAELRNEIYDLVFAPEPVYLCGATNIYSHQRTKHINLLQSQPPNYALLLTCRQIYLEAMQLYSDGYRAYQTPFAARDRKITALKERRARGVFWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ92</accession>
    <name>A0A9Q8PJ92_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767922.1">
        <property type="nucleotide sequence ID" value="XM_047911883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ92"/>
    <dbReference type="GeneID" id="71992613"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12735"/>
    <dbReference type="OrthoDB" id="3938188at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF1">
        <property type="entry name" value="ACTIVATOR OF STRESS GENES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="240"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="590" mass="65423" checksum="A6F9CF866CB6E8EA" modified="2023-09-13" version="1">MLRMVRESASVTKDSRTANSVDIEDESDHVQRSKSIARDNVVDILTGPEDDFISPSQSSGSPLSVLVPFKNLCTKAAGTPPSAAEQPRRTLAEAFDFDLLDTPSYNRMASFALLPSRERVQRMVSIALDSALNCQDPVDRERLGAQIDDLYERNADDYTQKNRQALGLVYALMALGRRYEPDAADENTNRGSELLVLKGVTYFRAARSIIDTSDTHDLDAVRTLVVMTVYLLSSSMISKAYTCICTAVNFSMRLGLHVSGASLASKFQNSELTDRRRVFAVLNLLDTYMSCILGLPNILRDADPSQIVPAPEEEMEDEGTDFVARNPFTPLSETILSAKLFRIEAEILGEQFSRDRYSVNDHGKHEIDYRFVANIEAKLQDWHEALPGMPPDSLGDQALKSQIMLRFCHAAVQLMLYRPFVHHVVRSQEDPDFNYKGYALGSSCIRTSMQAVWLVDAFDRHGYLHEALWQTIYILALAGSSLMLFVLGAREGSPTIAESRHAALKARELLGKLASKNISARRCFESLSDLPESAPARPPTQEDTSRDASPHSRFMMGIGAAVEPAATSVTPLVRMSTADTENDTRPLGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJF4</accession>
    <name>A0A9Q8PJF4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767908.1">
        <property type="nucleotide sequence ID" value="XM_047911700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJF4"/>
    <dbReference type="GeneID" id="71992430"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12552"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10907" checksum="3B636F1714AF9390" modified="2023-09-13" version="1">MHELTYTPLRSHALAFTNQHYGSATRQRVKPFRLLDLPAELWSKIGKIAIDDAPSFTYNPLALRYPPDTKGQPDITRICRVLRDGRQNLDVVSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK40</accession>
    <name>A0A9Q8PK40_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768321.1">
        <property type="nucleotide sequence ID" value="XM_047911874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK40"/>
    <dbReference type="GeneID" id="71992604"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12726"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="61" mass="7032" checksum="D3726AC2F636C0B7" modified="2023-09-13" version="1">MHPFSFPIVGIFVAGYITARWDLITQLYELAVFAWDHGVVHPRTQETGVSAREQLRRRGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLN0</accession>
    <name>A0A9Q8PLN0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769033.1">
        <property type="nucleotide sequence ID" value="XM_047912749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLN0"/>
    <dbReference type="GeneID" id="71993479"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13601"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18396" checksum="4752488E7660BCAD" modified="2023-09-13" version="1">MPSASHADLYFDPELEGWTDHITDISITNDCQDQSMAAESAIVSRVVRQIARKHKTSSSRLHPSKFSSMAEPPHDRSSSSSSSSSSTLSPSSLANWSSMADPVQERLAKPKDWSSMADPIHDPARKASKEVRGTEVDSQRTRGKDWARERSQSQESMKSSGSSDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM33</accession>
    <name>A0A9Q8PM33_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_14572</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Cytoplasmic vesicle</location>
            <location evidence="13">COPI-coated vesicle membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the COPG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769416.1">
        <property type="nucleotide sequence ID" value="XM_047913720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM33"/>
    <dbReference type="GeneID" id="71994450"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14572"/>
    <dbReference type="OrthoDB" id="1074925at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000046">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000071">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1480:FF:000001">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000008">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="14">
        <location>
            <begin position="20"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="15">
        <location>
            <begin position="651"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="16">
        <location>
            <begin position="806"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO25050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="920" mass="101107" checksum="CFA98F681E4E88DC" modified="2023-09-13" version="1">MAPYKKDEDDAGIVKVDRTSVFQEARVFNTSPISPRRCRILLTKIALLLSTGEKFPTNEATTLFFGISKLFQNKDASLRQMVYLVIKELSQTAEDVIMVTSSIMKDTAVGSDVVYRANAIRALCRIIDASTVQAIERNIKTAIVDKTPSVSSAALVSSYHLLPIARDIVRRWQSETQEAASSAKSSGGFMGFGGSSQQLHAANTNYMTQYHAIGLLYQMRSHDRMALVKMVQQYSAPGVVKSPAARVMLVRLAAKLAEDEQSSRKPMMKLLDEWLRDKSEMVNFEAAKAIGDMPHLTDQEANQAIHVLQLFLTSPRAVTKFAAIRILHQFASFKPDAVRQCNQDIESLISNSNRSIATFAITTLLKTGNEASVDRLMTQISTFMSEITDEFKVTIVEAIRTLCLKFPSKQARMLQFLSGILRDEGGYDFKRSVVESMFDLIKFVPESKEEALAHLCEFIEDCEFTKLAVRILHLLGLEGPRTAQPTKYIRYIYNRVVLENAIVRAAAVTALAKFGVGQKDPEVKQSVHVLLKRCLDDIDDEVRDRAALNLRLMKEQDDEVAARFVRNDSMFSLPVLEDQLAHYVNGGSAEAFANPFDFSNVPVVSREQSLAEDRTKKLTTATPTLKAPTVGPKKTDASAAEAAATATAVTQKYAQQLQAIPEFSSYGPVLKSSPVIDLTERETEYVVSAVKHLFKEHVVLQYDIKNTLPDYVLSDVTVISNPAPGEEGEESALEDDGFIIPVPLLKADEPGTVYTSFSRPADSFVPASFTNVLKFTLKEIDPTTSEPEEGGYDDEYQVEDLELTGADYVLPAFAGSFDNIWQGLPSADEASETLQLESIKSISDAVESLVKTLGMQPLEGTDVALSTSTHTLRLYGKSVTGGKVAATVRMAFSARAGVTVQIKARSEEDGLAALVVGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMB4</accession>
    <name>A0A9Q8PMB4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tim44-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769536.1">
        <property type="nucleotide sequence ID" value="XM_047913598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMB4"/>
    <dbReference type="GeneID" id="71994328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14450"/>
    <dbReference type="OrthoDB" id="19619at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024621">
        <property type="entry name" value="Mba1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051975">
        <property type="entry name" value="mtLSU_mL45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07961">
        <property type="entry name" value="MBA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO25170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="39675" checksum="A41B0BBC9270F67E" modified="2023-09-13" version="1">MSKRLCTSLLHAPQRSQASLPRCSIHSTFCIRRDDLHHRQFPSTRPFTSSTRCTSGPSAIRGMQGRKQSQPSMAVQMKEKQKSAQRDGSMLEHLGFLPDTFVSPTGKNLPSWFTSPKDRWKVQKLKLWNTFYYLASHYMAWWMVTPRVKLERRKLPELSKKLYEEMYTHFAAGNLQAIEPILSAGMLGSLRSRIGQRTPNTGLQWTLHRYLSHPRVVSYRFQILPDGAKTEKNAFAQAVVQIRSLQSLCKTRRLRVINNETRRGYIKEAVFDEQGNMIQDKDVEAHKRKIAKVTTEYLVVQRFVKLSRPGEWHVWGTVPETRMEDIRGKERENERELMSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQI6</accession>
    <name>A0A9Q8UQI6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="6">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06940</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="6"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763111.1">
        <property type="nucleotide sequence ID" value="XM_047906088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQI6"/>
    <dbReference type="GeneID" id="71986818"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06940"/>
    <dbReference type="OMA" id="YNEDWMR"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="9">
        <location>
            <begin position="132"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="32"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="565" mass="62581" checksum="BD6E5F3A8E350C60" modified="2023-09-13" version="1">MPPINRCVPALRRLRLANSNLQQSSHLRLQAARSAAQPLQRRWQHAEATTSAQQFGNQDPPPSRSGLSQKKIKTTAESYPDIKRDPRFKEITKDDVDFFRDVLGADNAIIDGLSQDASSDLEGYNADWMRKYKGQTRLVLKPASTDQVSKILKYCNDNLIAVNPQGGNTGLVGGSVPVFDEIVINLGRMNKIRSFDDVSGILVADAGTILEEADNHLAEHGHIFPLDLAAKGTCQIGGNVATNAGGLRLLRYGSLHGNVLGLEAVLPDGTIVDDLGKLRKNNTGYDLKQLFIGGEGTIGIITGVSIICPQRSPAVNVAYFGLSSYEKVQEAFKEAKKHLQEILSAFELMDGGSQQIYKRAAGAKLPLENDYPFYCLVETSGSNTDHDSEKLNAFLEHVMGEGIVEDGVVAENETQLQNLWMNREGISESSQHFGGVYKYDLSIPLPELYSIVEECRQRFLDNGLMSLDDESKPVLDVIGYGHMGDQNLHLNVCVRRYDKEVEKFIEPWVYEWIQKRSGSISAEHGLGLAKKNYIGCSRSENMIKLMGQIKKLYDPNGIMNPYKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQQ5</accession>
    <name>A0A9Q8UQQ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dual specificity protein phosphatase 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763278.1">
        <property type="nucleotide sequence ID" value="XM_047905975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQQ5"/>
    <dbReference type="GeneID" id="71986705"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06827"/>
    <dbReference type="OMA" id="DKKLHCQ"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008579">
        <property type="term" value="F:JUN kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="86"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="186" mass="21282" checksum="4357E0B7044EDF5E" modified="2023-09-13" version="1">MSRFWEFQQLQDSWKGASHFDQVPRAGKLYIGGVAAFYKEPDPLEQAGITHILSVLDFSINDAPQLKRCKCLNIQVDDDPDEDLLKHFPKTNAFLDDALREGGGVFVHCAMGVSRSATVICAYLIWKFGLSPMEALEKVREKRKRANPNPGFMRQLKVWERMCREKQGWDGDVYREWKEGGGKAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR15</accession>
    <name>A0A9Q8UR15_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763607.1">
        <property type="nucleotide sequence ID" value="XM_047906585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR15"/>
    <dbReference type="GeneID" id="71987315"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07437"/>
    <dbReference type="OMA" id="RLDHHKV"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17384" checksum="309BF76C37B57A90" modified="2023-09-13" version="1">MAPKDAAKSGKGKGASAKKPSAKASAAAKATLKGVNSHKTHKVRKSTTFHLPKTLTLSRAPRYPRRSIPREPRLDAGKVIVHPLNTESAMKKIEENNTLVFIVNVKANKRQIKEALKTLYDVDTVKINTLIRPDGTKKAFARLTPDVDALDIAATKLAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URZ8</accession>
    <name>A0A9Q8URZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764613.1">
        <property type="nucleotide sequence ID" value="XM_047909379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URZ8"/>
    <dbReference type="GeneID" id="71990109"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10231"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040316440" evidence="1">
        <location>
            <begin position="17"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="13585" checksum="A031DFA2101C3B90" modified="2023-09-13" version="1">MHVSKILAFAPTLALAAPLAVEKASGVRHDAAAKPDDAYQWASDSGYASFTKRAAEKKEIARDAKAKPDDAYDWASDSGYPVFTKRAAENKAVARDAKAKPDDAYQWASDSGYASFTKREAVQVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US41</accession>
    <name>A0A9Q8US41_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair protein rad9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764759.1">
        <property type="nucleotide sequence ID" value="XM_047909122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US41"/>
    <dbReference type="GeneID" id="71989852"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09974"/>
    <dbReference type="OMA" id="NETQCRF"/>
    <dbReference type="OrthoDB" id="60092at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="51379" checksum="C1F3EC3785BADC81" modified="2023-09-13" version="1">MATLSFSLTPEATGRVYELLTCLAKFGDAVSLEARSEKLTLTALNSSRTAYASFALHARAFFLDYDFKSNNAGSGGDRFTCQLYNRALQAVFKGRTADARGRETTIEQCDVTLQDRPDEAECRLVVKMVSKHGMTKTYRLTYEAVEVMHALFDKTAATQGWRISSKVLREYIEYFGPKTEQLDMLAQEGERKIIFTSFTEKIQDGKEVLKQPLETAIGLDAREFEDFHMQENVHIIISVKDFRAIVTHAETMKCPISTHFSYPTRPLQFSYQNFGIHSEFTLMTTGDYRGASATPTPRFVSTRSSSRQPSVVPPQSFSRAPSEMLPPARPNAGRPPLGSQSQRSSLREQVRPTAAMDEEPDPDSLFIPNDGGGDDDQAWEPPNYERDEEDEMLGWDASNNDLGASMRSQRPTIRDLKTAPPARTNRDTRQDREFGKSPDLANMPPTQRLSQLQGMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USA7</accession>
    <name>A0A9Q8USA7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tuberculostearic acid methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10852</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765015.1">
        <property type="nucleotide sequence ID" value="XM_047910000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USA7"/>
    <dbReference type="GeneID" id="71990730"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10852"/>
    <dbReference type="OMA" id="WGGLAEF"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="473" mass="53491" checksum="7BF054AC0CFF5A68" modified="2023-09-13" version="1">MTIVGQVTALANYAGTTFAWPPLLSFSRGAILATLRNIQIGSLTIIESDGSITSCGNRDRVSKPEDERTVNHIPHIELRVTNEQFWVRLAIFADMGFAESYMLGEFSCSDLTAFFRLFILNKQYLSNGVTFASNLLGKVTALVRKTNTLQNARLNISAHYDISNEMFAAFLSPDMTYSCPIWLPTTDAQSKQETLESAQYRKLNRFIKNARIKSTDHVLEIGTGWGSFAMLAVEKTGCRVTSLTLSEEQKKLAEDRIKARGMQKNIKVLLCDYRSLPVPEESEKYDKVVSIEMLEAVGAEYLSTYFSCIDALLKSDGGIAVFQCITIPESRYTTYSTSDDFIRRYIFPGGHLPTVTQLLSTIRSGSSNSKRGIEPRLIPHTVENIGPHYAKTLRLWRQDFMQKFQKEIRPALMQEYAEREKRKMTEDEVEVFKRKWEYYFAYCEAGFATNTLGDAIITIAREGALEIMEGVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USF8</accession>
    <name>A0A9Q8USF8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonribisomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765093.1">
        <property type="nucleotide sequence ID" value="XM_047909925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USF8"/>
    <dbReference type="GeneID" id="71990655"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10777"/>
    <dbReference type="OrthoDB" id="3791627at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="114"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="818" mass="88578" checksum="FA1A1ECF06D35965" modified="2023-09-13" version="1">MAILKAGAACVPLAPEHPRLRSKEMITSNVRATVLLTSRVHYAECADLVANVLVVDESTIGMLQDDGLQEVSVGTDQAAYILHTSGSTGTLKGVVLEHRNLTTSLMAYGESLTPPSTADERLLQETWASVLDIPVDKIGKETSFISLGGDSITGMQDVSRCGKRGVLLKMSDMLRSRSLLQAATHCTPHHVGAPGLRQKYIMPADEAAHIKEELGLGSAEFRGSYACAPLQEGILLSQARHATASPISDSGDLKFQHVAGELSTEYPLSFHVTTSKDYFHGEIQYKSTSVLDSIASHIADAVSSAITAILDDLQTPTASLELARSLLQRWNLEAPLALEACVHEQFREVALAQPERPAIHSSDNDLTYEKLDDLSDRLARKLQQKGVRAEIIVPMLCEKSSVAVVCCLAIMKAGAALLPLDPSHPSERLAAIVHDCGALLAITTASCMNQVEKLCQTVLPIDMGYYERLPADHDVQSDSSTPSNACAVIYTSGSSGTPKGIHPILRTVFVQDGQEVLQVVLQEAPIEQVYLSPAVVTDHSGFSPTKYLPTFHIFASTKDEVVLEIRIHHALYNAFSMDVILQDISAAYAEQTLTPRPNYHSRVSHVRSLDTTSAINFWAKALQGSSMTSLTPAEPPTRCSAAESSIEITMPAHSLQIAEVTPANVFKAAWATVFPQAVKSNDIVFGEIQTVRPSTFPEIDSTCGPSVNDLPVRVKLEDHHTSASLAAQIQSHSLDATPHHHLDIRSRSIIRDCTPWPAWTRFSSMMILQNHGALQAERNVGGVMCQLERLSYNGDSADVWVVAMPDGVFPRTGTTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI5</accession>
    <name>A0A9Q8USI5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_10939</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 11">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765182.1">
        <property type="nucleotide sequence ID" value="XM_047910087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USI5"/>
    <dbReference type="GeneID" id="71990817"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10939"/>
    <dbReference type="OMA" id="EMQYHTL"/>
    <dbReference type="OrthoDB" id="10056816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10507">
        <property type="entry name" value="Zn-ribbon_RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034004">
        <property type="entry name" value="Zn_ribbon_RPA12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF14">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="12">
        <location>
            <begin position="79"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="122" mass="13523" checksum="4FA4D814356ADD93" modified="2023-09-13" version="1">MAAIGSLVFCMDCGNLLESNTGRKAYISCDVCGAQNKDTSSKVVTSHSKPSAFPSALRTRLRSDVQEISEADRQTEVIIKHTCENCGNDEVKFYTMQLRSADEGSTVFYTCLKCNHKWNTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USW8</accession>
    <name>A0A9Q8USW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765541.1">
        <property type="nucleotide sequence ID" value="XM_047910238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USW8"/>
    <dbReference type="GeneID" id="71990968"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11090"/>
    <dbReference type="OMA" id="RRADRYM"/>
    <dbReference type="OrthoDB" id="4152802at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="939" mass="103446" checksum="44CB3D33606701A3" modified="2023-09-13" version="1">MPIWPFRRRRRGTQVNHDSDAAQASLLSEKARSFPSTQPSATTSAPSPVAHTPPIPTRSLRGHSERKRPASQQDQATPEQAVQPSKRRSHVDSANKENLLPPSSHGQYSSREDITALPSQYRLEHSPHLRPVDLERPPIPYNFRPRSVSQTVSSQRHEGTTKPARPRTLQSKRSTTDYGSPARILSRTSSKTSRKRDDQLREEEIRAMSAPIPIPKRRGDDPLRRDSKKIRGLGGRDSQVTLPPEGSVHSAMSGVVEQRGWEIGGFAVFSPRPAVRLSGTPQYVPASMPNRASGYLYRIDSLPKEKEKGKEMDNEKTPTSRDRDRKRRTVGNEADDLDASDIRLIMERDAKRRELRQKERQEKLERKLRSREGRNQGDSDARAARREEERRTQEEGRSRVEDEIQAHGPRPPPTAVHPALRNTAADEQPDPTPVGLGIGKQPPPAAPMESERQQQHALPTTEDLGTENTGTYRDYRPADAVPQNPFSDEAEFATPPFSTPMSEVPPAVLGASMPASPVEDTTAEDHNDEQPVLATAQAVRMSQANTPPLSPVYGVRGSGSASQLTEAVRQQSASALSTSVQSSDLPAPPPINVDRRSSDPPTDGPKRTDWGSIFKRGTFSRKKRPEALAPVETGFKNTSRESMRNQPIPAHLIDPNARRPSTLRSASGTPVRTQSKFREDLPDTPISPPDSRTQSPDVPTVAGAMAAREAGKNVPQPMDIPGRVDRSDTPVSQHVRGHAAMSGSLASIDSEGSWLASRSLKRQSNQSMLSRNISQRRAEFSASYEELGGDKDAEYLSRNRATHKASNPALMGASPDEESDDDVPPEIADDPLTVHGSVRRKPTLVQRDPRLKSREGLVTEFASAEQVESLAESLDATPDDDEFEPDSPGPQMERARSVNVGSRHSRQFSAGSAKLLDVRRTSMDLIRNSTTPEPRPTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUC0</accession>
    <name>A0A9Q8UUC0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766998.1">
        <property type="nucleotide sequence ID" value="XM_047911183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUC0"/>
    <dbReference type="GeneID" id="71991913"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12035"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="263" mass="29149" checksum="D4C1926C98835572" modified="2023-09-13" version="1">MGKTRAQDSAEKSAATPRKSAQAGVERPIAKRLSTTRASSKKSSSTGKPMSSTPSDQDQQPQSPVRVDSDDVTRGRRPGLYHFKLIDGKAIPQRIPSPDSSFKPRRPPAKQPPPKQLSLEEWRSAADRGMRLQEYIKKLLQLKKLLEDDSLNDIARTLEEAERQLYHKRMTWQDPPKEIDRGFFPLDEKTLARIAAGERVEELDKAFEKPLISTGIGLFGGSVNIPSEPPATPELEPARGIHQAIKATTYQGHVGVGLDEALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWB5</accession>
    <name>A0A9Q8UWB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoadenylyl-sulfate reductase (thioredoxin)</fullName>
            <ecNumber evidence="3">1.8.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">3'-phosphoadenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">PAPS reductase, thioredoxin dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">PAdoPS reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_14406</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[thioredoxin]-disulfide + sulfite + adenosine 3',5'-bisphosphate + 2 H(+) = [thioredoxin]-dithiol + 3'-phosphoadenylyl sulfate</text>
            <dbReference type="Rhea" id="RHEA:11724"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="EC" id="1.8.4.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="3"/>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769245.1">
        <property type="nucleotide sequence ID" value="XM_047913554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWB5"/>
    <dbReference type="GeneID" id="71994284"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14406"/>
    <dbReference type="OMA" id="PIARWTQ"/>
    <dbReference type="OrthoDB" id="7869097at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23945">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000151">
        <property type="entry name" value="Phosphoadenosine phosphosulfate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011800">
        <property type="entry name" value="PAPS_reductase_CysH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02057">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509:SF1">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="14">
        <location>
            <begin position="61"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00082553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO24879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="33653" checksum="0A6E4B42589DEABD" modified="2023-09-13" version="1">MAYRPRSNSSDRESGYASGSSTASLSDVYFSRPHLKFLNSQLAKLSPQDVLKWCITSLPNLYQTSAFGLTGLAVMDMISKLDFVLKPDIDLIFLDTLYHFSQTLDLVERVKTKYPHLTIHSYKPKGCDATADFEAKHGERLWETNDELYDFVAKVEPAQRAYRELGVQAVLTGRRRTQGGKRGDIDIVEVTEEGLIKVNPLANWSFKDVQKYVQENDVPTNELLDQGYRSVGDWHSTQPVTDSEDERAGRWKGKQKTECGIHNKRSRYAIFLAEQEAKRQEELSNAIHAGLKIESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWD8</accession>
    <name>A0A9Q8UWD8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_14376</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769277.1">
        <property type="nucleotide sequence ID" value="XM_047913524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWD8"/>
    <dbReference type="GeneID" id="71994254"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14376"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
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            <begin position="19"/>
            <end position="302"/>
        </location>
    </feature>
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        <location>
            <begin position="56"/>
            <end position="296"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO24911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="302" mass="32643" checksum="BBCA3626C186F9A0" modified="2023-09-13" version="1">MHSSAALVLTCLTSTAMAYPTLDQLATSGEFRQYQKQEKRQTIAFDALLQKVSTTGDHACQAPGSSDFRGPCPGLNSMANHAYIPRNGYTSNIQVIAAMREVFNISPEFGGFLTIMGSAMGGDGLGFSIGGPPPPSLPTATGLLGRPQGMRNTHNRFESDQSITRHDLYQTGNAVTMNMDLFKDLLTSSLPRGWYDIDVLGNHRVRRFEYSKANSPYFLKGLKTAFIPEATSALVTYLFANHSAACPTGCLDAAGLKSFYGVTGSGSNLKYTPGTERIPDNWYKNPIGYGVASRGSRRGLGR</sequence>
</entry>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE5"/>
    <dbReference type="GeneID" id="71993420"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13542"/>
    <dbReference type="OrthoDB" id="3649946at2759"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="75" mass="8014" checksum="9B85D1347D7AA693" modified="2023-09-13" version="1">MPSTQAQSARDKSAAVMAALKRGDEEEANRIMGKNNNTQGQLVPPGPMKWIKRKLTGGKSSHGKEGQGHGVGWSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWN2</accession>
    <name>A0A9Q8UWN2_PASFU</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetidae</taxon>
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    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
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    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <comment type="cofactor">
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            <name>heme</name>
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    </comment>
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    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>heme</name>
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        </ligand>
        <ligandPart>
            <name>Fe</name>
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        </ligandPart>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO25165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13494" checksum="AF8A341E8D28D64B" modified="2023-09-13" version="1">MTLHGHSFPAGTVVSSNAYCLHRNVDVFPEPLAWKPERWLGGKEEVAEMKKWFWAFGSGGRMCLGSSFAMIILKQTLAGVYREFETEVVDDEGIEQGTTFIAKPRGERLILRFGKVAGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWR6</accession>
    <name>A0A9Q8UWR6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Versicolorin B desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_14302</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="16">Race5_Kim</strain>
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    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
    <comment type="cofactor">
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            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO25301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="58466" checksum="0FCF9A63E266BDCE" modified="2023-09-13" version="1">MSSAPDVALSLRLTQLLPGLQTGDILTTILSILGIALSAIAAWGISTCVYNLYFHPLASYPGPFLWRASSLPWKIALLKGTMHHDLMRFHEVYGPELRLKPDELSYANAQACKDIHAHVPGRPEFLKDPIRLPLAPNGVMSILVSDTKNHARFRRLFGHAFSDKGLRTQQKTINTYADQFMEVLKEVADTGKSVEMVNYYNMAVFDTIGALAFGESFNSMRHRKIHPWVDAIHKNLKSVAISHVMRSMGIEPLTPYILPKDLRGARANNYSYAIEKINRRMQQTGEQGDFWDRVIVKSGAEGEINDGTGMSKGEMLNNAAVMVVGGSETSASALCGATYLLAHSPDKMKKAVKEIRETFKASEDITLQSVTGMQYLTAVIDETLRMYPSVPGQPPRVVPKGGATVCGKLVPEETRVGVSHIGTYFASYNFTRSHEFIPERHIDKSLFPDDNYAAYQPWSVGVRNCIGKNLAYAELRLILAKTLWHYDITLDRSKTGDFLDQKIWSIWAKRELWMKISLAENAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4W1</accession>
    <name>A0A9Q8L4W1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755276.1">
        <property type="nucleotide sequence ID" value="XM_047899437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4W1"/>
    <dbReference type="GeneID" id="71980167"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00289"/>
    <dbReference type="OMA" id="WRWIDER"/>
    <dbReference type="OrthoDB" id="3636749at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="31577" checksum="0584A94F640E3220" modified="2023-09-13" version="1">MAAPSLPVRHCAEQSTRKWSRKQHPIKQAALVTKDEVRGFHRPASEIHLPPEVHRLIYSYAAENCDPISPIVKESAAAAFSPIAQYIETGLPILHQVFPSLKDLATRLPKYYSSQVFQFDLRDEHGLSNSWRWIDERFEEVSAARTISLYHYTWYHSSSDYCWSYVPDATVLTLTSSGHIRLKRASQQLDPDSCVCAIADLVAAQFPDWKAKEQWTLLDFIAALRQDRDPLIDAVAKFIDVLQEHEEKFQKLEAGRQPCPARGKQIIFLRTTCNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L558</accession>
    <name>A0A9Q8L558_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_01525</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 18">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755413.1">
        <property type="nucleotide sequence ID" value="XM_047900673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L558"/>
    <dbReference type="GeneID" id="71981403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01525"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000198">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="6 18" id="KW-0349">Heme</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="9 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="20">
        <location>
            <begin position="425"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="21">
        <location>
            <begin position="604"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="18">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO11047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="995" mass="110155" checksum="586795D42B849BDA" modified="2023-09-13" version="1">MAPDKRDTEPIPHPRALPLVGNLFDVAGDVPILQIADLGKQYVQSSEGEIFSLHLGGKRRIFVNSQAMMNDLCDEKRFKKAVGVALQQLRSGVNDGLLTAYDGEENWGTAHRVLVPAFGPLNINGMFDNMKDIASQLVMKWARHGESYRIPVSDDFTRLTLDTLDPKTGKPLTDASAIDNMITFLIAGHETTSGMLSFVFYYLLRHPEAYRKAQKEVDHVVGRESVQPEHLNKLPYITAVLRETARLQSTVPAFAFETRSEQGELLGGKYFIGPDEAVIAVLHNVHRDPAVYGEDAEDFNPEGMLDENFEKLPPNSWKPFGNGARGCIGRPFAWQEMMLVMAMLLQYYNFTLDDPQYNLQIAFTLTIKPKNLHMKATLREGWTARSIEQSLSGSVPGTQHVPTVQPANSKPVNVTMDTNVTGKPLTILYGSNSGTCEAFAQTLAADASAHGFTATKVDTLDSARQKLPTEEPVIIITASYEGQPCDNAALWYDWVQNLPSDLKLKTNFAVFCCGHSDWKQTFHKIPIAIDGKLEELGGERLCDIGLANAANAAMMSDFQTWEDQTLWPALTKKYGGNASESGGAQFSQNVSVEVFSKRASDLRSDVYEAKVITSKLLTASGLSEKRNIELQRPSTMTYKAGDYCAVLPLNPPELVHRVMTRFSLPWDAMLKIASRTGSQLPTEHPVSAHNLFAAYLELAKPATRRNIAMLIEASNEDGVKNELTKLSGDNFTNDISAKRVSLLDLLEKYPTIQLPLGAFVGSLISMRVRQYSISSSPLSDPTKPSLTYAVLDEPSLSGRGRHVGVASHYLSTLRPNHVIHVAVKPSHQAFHLPNDAENTPLVMIAAGTGLAPFRGFIQERAAQIGSGRKLAAAHLYFGCRHSSKDDIYREELDFWEKMGAVTVHRAYSQAPEESRGHKHIDEAVLADKELLLELWEQNARVYVCDSRGLGESAKSACIEIAREAARRRGKPDSDEALNKWFESVRNERYSTDVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L584</accession>
    <name>A0A9Q8L584_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755457.1">
        <property type="nucleotide sequence ID" value="XM_047901141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L584"/>
    <dbReference type="GeneID" id="71981871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01993"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="32809" checksum="8E6CD362969A31F3" modified="2023-09-13" version="1">MATTVLLLASGSPTGTQHFTGELSPKESLESIQAGDLSVFAVVAKFSKKYATLNIEGGTTIEFAQTGAYNHTSKMRVVTTPKLEKFEPNNNGGLYERFTLTRLGSPDGQGRFVQDTLTTVQQMPATANRGPYEGLPPAPQPSHTDYNQLSSPIVAIGAQYKHSCNCWSRVSNQTVDAVDQDDNEQDEDADGGDQDDMDAVDEEEVQEGEEDEAGEANDTGGHEQAGEGQQFSHEDDYMQNSAAKGEIQDDEPGDARLEEAGQGPARGDQRWWRKFSGWRQIRFRGLGTGVPIDHLYRNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L693</accession>
    <name>A0A9Q8L693_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00008</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755986.1">
        <property type="nucleotide sequence ID" value="XM_047899156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L693"/>
    <dbReference type="GeneID" id="71979886"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00008"/>
    <dbReference type="OMA" id="AFNKWSR"/>
    <dbReference type="OrthoDB" id="296065at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="11">
        <location>
            <begin position="182"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="477" mass="53922" checksum="CF3292F086D9FDC5" modified="2023-09-13" version="1">MDYLIRFVQMHETFRKPEIDALAQINNISIEWLSYTEESHLSIIRFKDVSDPGLAAKALMSRSILAYGMYELWGATSGADYKDLHRDITTRSRHLWSHYGRQSFRFELDAFQGKRTMAEQRQIMEDLVFMGFTGPIAMKNPDNHFTIFEDYKLHAPAPHQLCFGRLVAEAGRRATATYTLKKRKYIATTSMDAELSLITANLALAAPGKLTYDPFMGTGSFPLACAHFGANTFGSDMDGRSIRGKKGRNVKANFEQYSTSSLYLDGFVSDLTNTPLREQRYLDAIVCDPPYGVREGLKVLGSERPHLQDVVYLADGTPAHLGPNYIPPKKPYSFLRILDDILDFGARMLTDNGRLCMWMPVAGVDVEEYEAEDEAKAAKVEVEVEYPVPEHPALELVSTCRQDFNKWSRRLLTYRRLRNDAVDTAALAAYQLKRLDLQADGNGKVTADDLNAFRRRYFQGFQKPSPAPQTTYTPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Q5</accession>
    <name>A0A9Q8L6Q5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756205.1">
        <property type="nucleotide sequence ID" value="XM_047901293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Q5"/>
    <dbReference type="GeneID" id="71982023"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02145"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="48805" checksum="5E3967C82EBFBF58" modified="2023-09-13" version="1">MASKSSSSSVSVRTCESVAQKLFIQCRDTGSTYKSLTASLRALRNVLGEVDEALDGHVGQQDDLNLPCGISKCEAILLKLEAALVLSRCSNQCEVNSNTIATFTKELDTASRELVTAYKKMTRTDVLSLSMRPDILSTQRTRSQSSRTSTPYCSTTKDIPGDTCSSGSAASSIGTTKRQSRSTTEKEVFYPDKQIYHHYHPDRANILQRSSSQASLRSKGSSSNARPDPYLASPFEAACGLIHNDDTLVGQMAKSELSWIPSAELQGDEKSPSVRKQQLPEVGAADLMASHGRKDSLLGDVEANVNRQTKRSDERVEILQLKVLDQEDHIALSAAEGPFGDGNETSAIGLTTTAREDAALPLNDCECDEKSSFITGDGLSTGGCRALAAYPARPSPPTPANTRVGLKELVLPTPLPRLPEDVAQSTALPDSDSEDDLYDSTPVMRPVPDDDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L773</accession>
    <name>A0A9Q8L773_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U4/U6.U5 tri-snRNP-associated protein snu66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756407.1">
        <property type="nucleotide sequence ID" value="XM_047900621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L773"/>
    <dbReference type="GeneID" id="71981351"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01473"/>
    <dbReference type="OMA" id="KRRDYTG"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="357"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="533"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="635"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="670" mass="75568" checksum="7318AE0CB4C65BA3" modified="2023-09-13" version="1">MASGMSAEQIEQMNKVRVSLGLQPLEVPGQGPQFKEDDDGSDSDQSEDLSTLEKRAAAAGNNWQRHEAERKEKEERQKRKDAAKKARDLAARNEKLQGKGLGDEDAAEEVDTRTWLLQQKKRQKKIDKARKLEEELAAREQQAEYTAKDLAGVKVGHEAAEFDELTGEQILTLKDAAIGEESEDDELENTDLKAKEKLEEKLKLLKKRPDYDPTEQGEQKNLLSKYDEEIDGKKQKRFTLDGQGTAAEALKRKAANEGEVKGKGVKISLDILKDDAPTSDYVDPSTIKVKKAKKSKKEKKTRQKAADEDDIVPLVTQSASVSNGDAMDLDNEQEVVTASKKRSFEFDDDEDLQAKLAEQRRQALKKRKKTDAAELARQMREEMPVDEPEPEEEGLVMDETTEFVANLKKPDEADEDDIRAKRSKSAQPGAAGSPDVQDEDDDGDTNMGQQSYADAEEEEERQVRIKREASNAAEISATGLEDEESLVGSGIGASLNMLRKRGLIDSPAAEGSVERERQRMKFLADKQQLVEEYDQRAKDQREADRRSGRFDKMTNRERDALARQQNEQREQYISRLLAEKFNKEYKPDVKLRYNDEHGREMNQKEAFKHLSHMFHGKGSGKGKTEKRLKKIEDEKKSAARGMLNVGEEGGFSNVQGREGKRQKTAGVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7F9</accession>
    <name>A0A9Q8L7F9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756495.1">
        <property type="nucleotide sequence ID" value="XM_047901393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7F9"/>
    <dbReference type="GeneID" id="71982123"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02245"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF9">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="24"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="440" mass="48962" checksum="CF2EB6F7342ED8A9" modified="2023-09-13" version="1">MTRNTMPEPEPVSDSATSNSRPDFDALVQHQLDKHKLPGASFSLVHGKTIWSKGYGLADLSTGRDIDANITLHYSASTTKAFLTTARALYINSNANKRKPDHEKISFSTSLSKIIRDDSVLPNPFSTERVTLEDVLSMRSGMARHELAYGREEAYTPRDVVRNLRNLPVHTELRMEFEYCNTGYVAASHALEVVTGRPLVDVLREWIWEPLGMGSTFGGYDEVVARGQEGRMAKGYTWSKLPHHEDFGDGEFRAEEPMDLRPVSGAGYMISTGDDYVKWLKALLSRSDLNPITVEITKGCFSPRMICPPTGVSEAIFDGGHLLYALGWFVASYKGHRIVYHPGGLVGGGSRVLLCPSIKFGTSFLSNGFGAGERLASLQLWLLDRALGLGEKECDGFEKRKAQSRIGEDGQVQAFGIGMEPAMRDELFWFDRKDRRKVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7J8</accession>
    <name>A0A9Q8L7J8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">High-affinity nicotinic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02202</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756673.1">
        <property type="nucleotide sequence ID" value="XM_047901350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7J8"/>
    <dbReference type="GeneID" id="71982080"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02202"/>
    <dbReference type="OMA" id="FYTRYEF"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF21">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="48"/>
            <end position="550"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
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        <location>
            <begin position="276"/>
            <end position="319"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="615" mass="68835" checksum="99B5880AE980A7D1" modified="2023-09-13" version="1">MNTSRRFQQRHDEEQQTLIGGERNATQPANDDSTLLNRRTVRKLDTILLPFLALLFLLNSLDKSNIGNAETAGFTHDTGLSRNDVNTSMAVFFFVFVLLQPLGAALGRKFGMRRYVPICMSIWGLTTILHVFVSERWHLIVLRVMLAVLEAGFYPTTVSYMSLFYTKYEFAFRLGFFYGMSAVSGMLGGVLSWAVFSHFEGHGDGGGNTPELPPTRRHEDRPEGLKSWEILFLIEGCMTMAVALVGFFWLPKSADTAWFFTREERDHAEQRMLVDTLAISEPQKSNEDSPSSASRYGEEDDRERPMPVQGEGTGDGDHERLLGGNNLHEILRRTVSGVSGHPITEDSGLTKQDILSAIFNYKIWHLLFVNILSAIPATAFGVLLPILVKELSPSLNLSPAASNLLSAPPFAFGAVALFVFTIWSDRSRKRLTPVLWGLALLLIGLMMTILSPLSNYWLRYFSLCVLLSGSYIASPLTVAWLTNNTPEPGKRAILLGINGWGNLAGCFMSVLFTPEGEETGYFRSFLILLICVLISFAGFVLFRAILIRENRYRDNVLRSWSDEEKEREELVGDIPAPDNFGQRLARKLGLLALAKRAGSDEARKGDEKLTYRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L868</accession>
    <name>A0A9Q8L868_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_01928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756933.1">
        <property type="nucleotide sequence ID" value="XM_047901076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L868"/>
    <dbReference type="GeneID" id="71981806"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01928"/>
    <dbReference type="OMA" id="IQFIGHY"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046521">
        <property type="term" value="P:sphingoid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
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        <location>
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            <end position="72"/>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
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        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
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            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="22392" checksum="BC07F8A16B238866" modified="2023-09-13" version="1">MALNLEKQLLFYGSYHHDPVNIGIHITFVPILLLTGFLFGTNTPAVSAPEWLSIPYLPYNLGTIACFLYSSLYVLMEPVAGAMLAPLLLGGTAYANHLTSTHGMKANYIAIGVHIFSWVVQFIGHGVYEGRAPALLDNLVQAIFLAPFFVWLEILFAFRYRPELKARLDTAIKAEVAKFKAQKQGQQANGDLKAKDVTNGHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8C9</accession>
    <name>A0A9Q8L8C9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-carbamoyl-L-amino-acid hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8C9"/>
    <dbReference type="GeneID" id="71981528"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01650"/>
    <dbReference type="OrthoDB" id="4676at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03884">
        <property type="entry name" value="M20_bAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494:SF5">
        <property type="entry name" value="ALLANTOATE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="ALLANTOATE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="283"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="55673" checksum="75D98AD59B7F8207" modified="2023-09-13" version="1">MSTSLRTLTSTTRLATSTTRLATSTTRPIRTSCSRWQARRAFAASARPQLAVSEMAERDLASLKIDQGRLMNDIHSTSEWGKGERWGDGDTEIGMSRLSLSDADKKARDWFAETTKALGCKVTVDAMGNQFAVRPGLERGYPVYAGSHLDTQPTGGRYDGILGVCAGVEMLKTLNDNWVETAYPVGVVNWTNEEGARFPKSMVSSGVWAGSIPIEDAHNLKSVIPANDTATMKSELERIGYLGKTPASHKNTPMAAHFELHIEQGPILEAENRRIGVVEGVQSYKWFTLTVHGLDSHTGATSFQHRADSLLTASKMIVASHKIAHKHHALASTGILNLEPGSTNTVPGFVQFSLDIRSPHDSTVETVEAECREAFSAIAAGKDDFGTASSSRHCTVEWRTDFTSPATHFSTDCISCVKGAGAALCGVNARGEHELGAGHVEGKNIGSWGKLMTSGAGHDSVYASKHCPTSMIFVPCREGVSHNPREFSTPEQCGDGANVLMGAVLRFDKMRHQRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8M4</accession>
    <name>A0A9Q8L8M4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757195.1">
        <property type="nucleotide sequence ID" value="XM_047899879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8M4"/>
    <dbReference type="GeneID" id="71980609"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00731"/>
    <dbReference type="OrthoDB" id="2532734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="70" mass="7668" checksum="64D3B9571E00B897" modified="2023-09-13" version="1">MPVIPQDSDKEMKEQLSQGAKDAKAAKDERQGNVATAEQHKANLGPAIAENLPEPASKEELKKRSEELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Y8</accession>
    <name>A0A9Q8L9Y8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757878.1">
        <property type="nucleotide sequence ID" value="XM_047901748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Y8"/>
    <dbReference type="GeneID" id="71982478"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02600"/>
    <dbReference type="OMA" id="DFLESTW"/>
    <dbReference type="OrthoDB" id="3353407at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="125" mass="14062" checksum="CF1865C26A6FD203" modified="2023-09-13" version="1">MRLSVQLLELMDLENVKGRGMMFEMWPPTLAYHHALKAVYAPAPIYMERKWPGSLLQSNFNGGKDSSIGGSSSSVLNHEQDFLESTWYWNAKWPMEIYERWIGVATSGPGSSKVLAYPVACYAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAB4</accession>
    <name>A0A9Q8LAB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758186.1">
        <property type="nucleotide sequence ID" value="XM_047901848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAB4"/>
    <dbReference type="GeneID" id="71982578"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02700"/>
    <dbReference type="OMA" id="YLPDMFL"/>
    <dbReference type="OrthoDB" id="4034134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038872">
        <property type="entry name" value="Put_GTT3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41807:SF1">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="372" mass="40820" checksum="F672D49E1056DD25" modified="2023-09-13" version="1">MAHSWLQRQKKAALLELSVEAGLPQEDSLLKDEILANLETYLDLNATTLSRMSVFEDYYGKRAQTPARGRPPRDSIYVPAEDNEIKSVVKARGRRATQIKQEPEDDGPMSSPVAAAVATATSSARRAVNTVSSALSPSGQLTARTPAARPVGRQRRRSELPGPPSPADVADVVEYESRAFVQKVEDLYAMLGVNDYVQNVRDTLSSVTAIQMTFLLIEAFALQRNLMPWQYVMEIPSTPFTSSFAVFAPDLFILLTGYYWSATLLWASTSIFVPSLFAYFYNLTIRDVKRGSRIVPVARYAADPLTFHVVKALATWLVYNQGVTFGGWIDPIAAERVELALYGGHTATLIGSAIGALAALYEAAQKKHVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAT1</accession>
    <name>A0A9Q8LAT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Malonamoyl-CoA synthetase vrtB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758383.1">
        <property type="nucleotide sequence ID" value="XM_047901657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAT1"/>
    <dbReference type="GeneID" id="71982387"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02509"/>
    <dbReference type="OMA" id="DWYREWA"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030729">
        <property type="term" value="F:acetoacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002937">
        <property type="entry name" value="PRK03584.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF1">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="6">
        <location>
            <begin position="42"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="116"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO14017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="681" mass="75869" checksum="FBB3FD264BA9B616" modified="2023-09-13" version="1">MADLNDIPKAELLWQHPSPKDSKLWEFLQTVNKKHNKNFQTYQDLYQWSIDNVSDSWGDIWDYVGIRASKPYEKVISDEQTMYPRPHWFPGARLNFAENLLFPTQAVDEYSLAVIAATETTRETVTWKELRERVRKAQGGMQALGIKTGDRVGGYVANHTNALVAMLAASSLGAIWTAVSPDTGVTAVLDRMVQIEPSILVTDNAVMYNGKTHPVLPKVKEIVESLPTLKAVVIFDTVSSMGSEVEGLSDQFKQKVYTYDRFTQSSGESTKLHFEQLDPDTPVYILCSSGTTGAPKCIVHGAIGTLIQHKKEHVLQSDIRPGDRLFYFTTCTWMMWHWLVSGLAAGATLILYDGSPFQYLSNGESVKDDLAMPRLIDELNITQFGTSAKYLSVLEQRNIFPKQQGLTLKTLRAIYSTGSPLAPSTFQYVYKAFGAINLGSITGGTDIISLFGAPCPLHPVYIGEIQVLGLGMACQAWDFEGKDVSKKGEPADLVCVKPFPCQPVMFWGKEGEAKYKASYFEEFPGVWHHGDFIRLNPETGGLIMLGRSDGVLKPSGVRFGSAELYNVLLKHFPDQVEDALAIGRRRERDDDETVVLFLKMKQGEKFSEELVQGIKGVVRKELSARHVPGMIDECPDIPVTTNGKKIEKSVKQILCGLNIKTSTSVANPESLEFYKKWAETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAV1</accession>
    <name>A0A9Q8LAV1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758327.1">
        <property type="nucleotide sequence ID" value="XM_047901537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAV1"/>
    <dbReference type="GeneID" id="71982267"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02389"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="52479" checksum="9F94F0CF291CD4DC" modified="2023-09-13" version="1">MSSPVDSVLQETQPSVAHVPINGFNLHELQALADEQPFTEPYKPPGGFPEPEWAPDCMTDGGSFFDHLQKEYDRACHPTSPVEASAASPSASVSDPSTQHDASVEAIVEVYKHFEGLTLSTEPVDRYKSKLDWFMVEVFMAIGFACDVICDSNRTLLDSLKQREQGFLVAVVLFREGDRRNEYLCGDERDQWRIPRFRDLFTMSELNAAFTAREPVVLKVILKISNTPLLAWTQRDPRSSKSTLFIYGTKQKGCHEPRQEVARVNDNKVIESDLTTGELYVWQGTSPRKAVLDENIGKVYPPLPPGVTPQDGPRHPFLTYNTFTFPANPGPNPNHLQISLMVRLVSHLHSTSFAGIELPAHMCIHDSRTGRGVAKLRSAIKKALNDSIFDLDAGKEASDHRRVHWLFDHGASKRWDIEFWVIPQPESGSVVGQYFYRWEGGNVTQWFRRDGRGQRIHVEAHFVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBI4</accession>
    <name>A0A9Q8LBI4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">5'-AMP-activated protein kinase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758702.1">
        <property type="nucleotide sequence ID" value="XM_047902234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBI4"/>
    <dbReference type="GeneID" id="71982964"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03086"/>
    <dbReference type="OMA" id="YTCSPDD"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="245"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="322"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="396"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO14336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="456" mass="50351" checksum="FC4D885FF39FAA62" modified="2023-09-13" version="1">MMEDEARTNQNSGRRRTASSSRDHGLNSSSALQDHEHGSTAGKHDAQKAPSHQTLEHTGVQAKVFTTSPITGTTPPLSTAAPSVAPLPVTVPAALPFVAPSDLLRPQASRAQSSWGTAAGTGADAVARDSVDRPMTPLDREQINGLRAIRAFLKVRTSYDVLPLSYRLIVFDTSLLVKKSLNILTQCAIVSAPLWDSKTSTFAGLLTTSDYINVVQYYWQNPDSLQQIDQFRLNGLREIERAIGVTPIETVSIHPLQPLYDACRRMLESRARRIPLIDTDDETQREMVVSVITQYRILKFISVNVKETQNLRKPLRDIKVGTYTNLATATMDTPVMDCIHMLVKKSISSVPILDPKDGTVLNVFESVDVISLIKGGDYENNLNLTVGKALDKRSDDFPGIYTCTLNDRLDTIFDTIRKSRVHRLVIIDEQNQLKGLLSLSDILDYTLNSPLGDGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC35</accession>
    <name>A0A9Q8LC35_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ATP-dependent helicase irc3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02973</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759002.1">
        <property type="nucleotide sequence ID" value="XM_047902121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC35"/>
    <dbReference type="GeneID" id="71982851"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02973"/>
    <dbReference type="OrthoDB" id="16911at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036121">
        <property type="term" value="F:double-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061749">
        <property type="term" value="F:forked DNA-dependent helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032042">
        <property type="term" value="P:mitochondrial DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18032">
        <property type="entry name" value="DEXHc_RE_I_III_res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18799">
        <property type="entry name" value="SF2_C_EcoAI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050742">
        <property type="entry name" value="Helicase_Restrict-Modif_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE IRC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396">
        <property type="entry name" value="TYPE I RESTRICTION ENZYME ECOKI R PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="77"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="296"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="670" mass="74952" checksum="B5BF40A05D3C8BA7" modified="2023-09-13" version="1">MWRPLPIVRLAQRLPIARATLQTSAARRRSIVPRSWVDQPGCMQRCMRYSSTCKISAATGPVQLRDYQESSIQAVLDHLSRGEKRLGISLATGSGKTVIFSHLLDRVPAPSKNATHTLILAHRRELIEQAARHCQQLYPDKTVEIEMANSKASGLADITLASVPTLARSAERLQKFDPARFKLVIVDEAHHIVAGSYMTILEHFRLANPNNLGPTALVGVSATLSRHDGLKLGTAIDHIVYHKDYVEMIEDEYLAKAIFTTVKTGVNLDKVKVAGGDFQSKALSKAVNNPETNLITVRAWLEKGGSRKSTLVFCVDLTHVADLTAVFRQHGVEAQYITGSTNAQERAERLQAFKNGEYPVLLNCGIFTEGTDIPNIDCILVARPTQSRNLLIQMVGRGLRKYEGKANCHVIDMVASLEGGIITTPTLFGLNSQELVNEADFKTMKSLKERKEQEKQREEQAMQAASQPPPELKGDVIFTDYDSVNDLIEDTMGERQIRKISPFAWVQIDDIRYILTNLDGANVSIKKEGSDEYVLWYTARLPDGTTSKAPYARPRQIGKSATFEAAVHGADTFASETFSYDMISKSAFWRKKPASQSQMDYLNKFRQEDEQLQFGMITKGRAGDLITKIKHGARGRFRRMTGEKKKAQKKVQRWQDRQSREQVRVGPVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC54</accession>
    <name>A0A9Q8LC54_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08186</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759032.1">
        <property type="nucleotide sequence ID" value="XM_047907334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC54"/>
    <dbReference type="GeneID" id="71988064"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08186"/>
    <dbReference type="OMA" id="LLRKEMW"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF41">
        <property type="entry name" value="CHITIN SYNTHASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="584" mass="65779" checksum="A70437D25B4B58D1" modified="2023-09-13" version="1">MTEGVFSPTEEEIERFYTTPGPGAFDLDVEKGLAPDQQPVNPARILTRRELLHQRLVFASIVFAFNVACIVVSAVGYSGVWVLCVILFFKSKDFLSVWIQVFCRIYYAIKKLFVALPPRKAAWILSLIPAYSESEEQIVKTLFSLRDNGTGQHRQVMCIILDGKPRPIKEHMTKVVASFERQYVSLKWKVGTLKIDAGFVDDIPTLCIEKSPNAGKKDSLVLCHDLFNHPRANIDKDVLRLREELWTTILPQLTKLPDFEAFDSIFGTDADSTIHQGALASLADACLADPNAIAACGFVFVEYEAGLEWSVWNLYQQFQYSFGQIVRRGAEHFTGKVTCLPGCITMIVVRPEMAGAIQKYAKPVTDYPVLRHQVQYLGTDRRLTYSMLSQGKHLHTLFVPEAGSETVAPQSLKHYLSQRRRWGSNAYFNNYFYLAGENMIVITRIAALIEVTRLSMVYYRVFNTGLFLYGVATNFKLMKILPLLAISFTPSVWFAFAVVFLNGHLRRNWHKLLCGFIINRCVSPFMSITVFSLVARNLGSQVWGISGVTAGTNVTLAVATQAIAEEKAAERASEDLYDRKDLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCR7</accession>
    <name>A0A9Q8LCR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759355.1">
        <property type="nucleotide sequence ID" value="XM_047907042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCR7"/>
    <dbReference type="GeneID" id="71987772"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07894"/>
    <dbReference type="OrthoDB" id="5385189at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="33036" checksum="1075479DC04652CF" modified="2023-09-13" version="1">MPTRIDDRYLWLGFGIFLFFAAQGIRHAITNTVRLTELEPIHSRKDDEEDQQPEDRIEISTLEILARSPNPNIAASAASLIVTRFAALPDAAEIISTDLQSEDEDTRRKARQAISYLQDWDTALSTSLDESRTFAAREALVQAARSLRPIHSSRSTIHLPTLDEMQSVANVAGGLVSLSDLEAEGERQRETRQLDVVSRLDELAEQAGHSEFGWRTHEEGPGSARLAGWDRIPSEMAWDEGGAWERRMRRNRDSGDAWSTRMRRRNREAVVVGVDVEDGEDVGGSSVGGGAGWRAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCZ6</accession>
    <name>A0A9Q8LCZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proline-specific permease put4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08236</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759498.1">
        <property type="nucleotide sequence ID" value="XM_047907384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCZ6"/>
    <dbReference type="GeneID" id="71988114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08236"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="53"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="247" mass="27071" checksum="E1C489030BA118DF" modified="2023-09-13" version="1">MDVPDIDTEIAKVPITSIHPDSPSQLDRTTRLSSPDDLTAKYGRTHRGLANRHVQLMAIAGSIGTGLFVGIGASLSTAGSLSCLLAYIIYPTLFMWPCNMRVAEMATHLPIRGSIYEFASRFVDPAFGFALGWTYFYASSMLWCAEICAVATVMEYWDLGVNSAVWVAVVIVVCLGLNVFAVKWYGESEFIFGCTKLLLIIGLCLLTFVTMVGGNPKHDAYGFRNWTDGNAMHGYYTDGVTGRFLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD37</accession>
    <name>A0A9Q8LD37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD37"/>
    <dbReference type="GeneID" id="71988416"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08538"/>
    <dbReference type="OrthoDB" id="5426798at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="336"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="400" mass="44036" checksum="4DA4B1F81E6478C9" modified="2023-09-13" version="1">MFSVVHQDYSDSCALSQILIACLSPWDVLVSPCCILAITAHLCSLYDMSSYYQPSCPNITVPSESAFEPQRPRYDPVTEVSPRIPREQSSEKRTTHRVTRQPSQGSPPTRSLPGLSELFASRLLVAPNPKQDRTASASLSAILNNPSGYKEVSKPSTRPYVPNVGRQSPSRHAATPILSSSVPTTPDSWTSELPPLLQDTQVHGFTRSLQQANPGSPPFHSESFGASVVGGQRAFFTSEQSASRYGHSLPPTHHNEEIPVHRVDSRAGWTESDLRPAVPELLPATYMYRTDCGMISGPQPYADCAVGFSVPGREDLVYPMWDLTKRKLPRKRMSTACTDCRKKKIRCEPGAGGCLQCRKAQKPCVIEPVKRRRRRKALSSDADAEESDNGSEELEKARGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDB5</accession>
    <name>A0A9Q8LDB5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759646.1">
        <property type="nucleotide sequence ID" value="XM_047907531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDB5"/>
    <dbReference type="GeneID" id="71988261"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08383"/>
    <dbReference type="OrthoDB" id="3918336at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="55093" checksum="DB79D3C6EC8C4DB0" modified="2023-09-13" version="1">MAQLDGVKEELRKVIYACDTEKADPVGDRAGDTVDELSDQAMQQKLDALPQYTCDFLDATISGQTDVVVVQNRLGTNRDKTVQARAEPVINKLNNSDFNDLDDKVCAILQGCVNEIMSGLLLDRFKANLTAFEDITGRPPLIKDAHSKEYVFENAYRLLELVKDNMFHVKVLAAQLRKEGLLAEGTTDEQYQGALRPMFALVAVMYGCVREGSVWLTVMDSLIEDLARLVRGQVDPRHATEKMTLVRRMRTNETNVDQVLSLSDADRASLKLDDVARRRFAELARFYLGAVMLAFAAVSWKSKSNDESWLQWYGELLQWQHACGAETCTEDLIVRRPAVYDEELGAGDQVAALSDNEAASDENDEISDDDAMVIDLAAAKIAPKKVAPKKVAPKKKSARDGVISRSRYGLSVGVLDARKGFPSERAQISENREWAYPCLYRLTCWNKWHPGFGPFFHYFAHLWHSPCMPARDKIAFIMTIDNAARKAKDAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDN6</accession>
    <name>A0A9Q8LDN6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759864.1">
        <property type="nucleotide sequence ID" value="XM_047907430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDN6"/>
    <dbReference type="GeneID" id="71988160"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08282"/>
    <dbReference type="OMA" id="GHFMFWP"/>
    <dbReference type="OrthoDB" id="5416609at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF20">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13207">
        <property type="entry name" value="AAA_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="2">
        <location>
            <begin position="477"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="744" mass="81759" checksum="6EFED9AF8BFD67C7" modified="2023-09-13" version="1">MSNQAVNTSPLSTHEPGVVGIYGVSGSGKSTIKTNLSQALAQEFIFYEGTEVLLKAVKRDLQAFKNSDEQTRLQGRTQAIRNIVQSSTESGKVAVVTGHFALPSKQESIFHEIWTPADEASYNLIVYLEVSPDHLAKRINQDENRGDRKVRDPEQLRDWQEQEIHGLRAKCYSNNILFVSVNNDDPSAAKITIEKILKAFSRHSEKKQSAQLLSKLESIFGPAPQKKEDPKPHDAVLVFDGDKTLASQDTGELMLPKTNTSDQATPLKQLFSSDLGYSFAAWSQAALLYDALGDDAAFDKQCEDVAVQVNIHPVFVEMLKSTRDTKHVRAIVVTCGLQRVWNKVLEKAGLSDVLRVVGSGRFSEGFVVTPEAKKQVVERLQKGYRQYVWVFGDSESDLPMLQAADDAILVVDGQKRSQSTQDKIRAALSDGLRPRQLLMSGPGSSWLKDTRAPVIYMNNLEFRKALSGDFHLMHTSDTSACKLLATPMRDASISSATLRKAHQNAGEYIARELIAKKIGLQQYDTDHVQEGKTTDGWRLFHENKITIIALMRGGEPMALGVSEVFPQAMFLHAKKATNVLPEHLHGQSTVILVDSVINGGGTAVEYVKRVRGLRPTIQVVVVTGVAQKDAVKEKGKMEEQLKGCGEVTVVALRVSENSYQGKGGTDTGARLFNTTELEKGREDGQQDGQQDGQEDGQEDGQEDGQEDGQKDGQEDGQEDGQKDGQEHGQEHGQQEVVAQPGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEB4</accession>
    <name>A0A9Q8LEB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA dehydrogenase apdG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760188.1">
        <property type="nucleotide sequence ID" value="XM_047904215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEB4"/>
    <dbReference type="GeneID" id="71984945"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05067"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF15">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE APDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="2">
        <location>
            <begin position="155"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="22042" checksum="7F122CC5D47536A8" modified="2023-09-13" version="1">MGHSVDNNPFAEAPWLMGVPSPYYSDSHRRWQKTCREFVWKNLGQYGLQWTRQQSCEPEVYQTFADAPCLPAPLPIARLKALGIRELAGSLKLEEYDYFHYLIYMSEMYNCGLFSPAGVVVPGMAFGTPPILNYGNRELQDRVLPDLLLGKKRTCIAVTEPGAGSDLANLETEAIKDASGDNYIVNGCKKWLVVGQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEH6</accession>
    <name>A0A9Q8LEH6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Baeyer-Villiger oxidase ptaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760422.1">
        <property type="nucleotide sequence ID" value="XM_047904142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEH6"/>
    <dbReference type="GeneID" id="71984872"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04994"/>
    <dbReference type="OMA" id="KFDFFYI"/>
    <dbReference type="OrthoDB" id="10004862at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="49638" checksum="169C38B8B18C57D2" modified="2023-09-13" version="1">MASASTVQLQLDQHPVYYRNGISNESTKKVSELMQENHEKFHIFFNNDGFHNHIAHQMLTMWALKASPDQIRREYNSNKLYQRPSQKPDTKTLQDLSDPQVFIKHLGPEQHYNDFLEFFKAEMEKSSWQEVINKYLFAGDERAETMLVRMYAGFLHPIIHLGFGIEFQQPAVIAEGLAQAACHDDWIGRLLLPAEKAAKDRADASSKSIAQLLDEIHDDSALQSAARWSDGNKIRDGILARAGDRMIDIAAQVCVKPEELQEKTAEMTNAVAYYTGGAQKADKAVKFDFYYIHCLNSSIFFASFLKQDWLSDANKVRLLEWKIRLDLAMYASRKAPEIRLGDIQNYQPKKPSGWDAVQDRVCDIDDDGHASKLVRAIANGGQICAPYEGKDGFRLKGNDWLSLAHMAIDSVELPGDRWVRSAGFDEAWEKVPLRANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEI3</accession>
    <name>A0A9Q8LEI3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_05120</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the U5 snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760348.1">
        <property type="nucleotide sequence ID" value="XM_047904268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEI3"/>
    <dbReference type="GeneID" id="71984998"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05120"/>
    <dbReference type="OMA" id="ARDIKHM"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000322">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25430">
        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="379"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="593"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="755"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO15982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="783" mass="86517" checksum="69B3CE4DADB9421F" modified="2023-09-13" version="1">MADMDAPPPPPPSDPIPPPPPPPSDPVPPPPPPSDPIPPPPPPATNGHEDDEHFQPRVDLPKKRKLEPRPKVAPLSVEELLARKKAQDAAAAKPKFLSKKERERLAKEKGAREAQAQKANEPKEPERVAPNGPCGRPTGPRSMRDGGRDAPRGPAAMRTQLPNKGYDMQPPPPPSRDAKIVDGPKSNKKQSEREVEAEMTKQRYMGADTNTSTFSAKKKRKRTTEKKFNFEWNTEEDTSPDYNPIYQSRQENSFFGRGRLGGFTDDSTDKQAQQYAAAIAARDPEAGRERAQAILEAERKRREEGGRTGVEKHWSEKKLENMRERDWRIFKEDFNIATKGGSIPNPMRSWAESGLPKRILDIVDQVGYTEPSAVQRAAIPIALQSRDLIGVAVTGSGKTAAFLLPLLVYISELPALNEQTSNDGPYAIILAPTRELAQQIEIEAKKFATPLGFTCVSLVGGHSIEEQSYNMRNGAEIIIATPGRLVDCIERRVLVLSQCCYVIMDEADRMIDLGFEEPVNKILDALPVSNEKPDTEEAENSMMMSSHLGGRDRYRQTMMYTATMPAAVERIARKYLRRPAQVTIGNVGEAVDTVEQRVEFLQGEDKRKKRLGEILNSREFAPPIIVFVNVKRNCDSIAREIQRMGFSSVTLHGSKTQDQREAALASLRDGSTQVLVATDLAGRGIDVPDVSLVVNFNMATNIESYTHRVGRTGRAGKTGVAITFLGNEDADVMYDLKQMISKSSISHVPEQLRKHEAAQQRTGKGQKKNIEDSGGFGGKGGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LET6</accession>
    <name>A0A9Q8LET6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonyl/alanyl tRNA synthetase SAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760450.1">
        <property type="nucleotide sequence ID" value="XM_047904312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LET6"/>
    <dbReference type="GeneID" id="71985042"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05164"/>
    <dbReference type="OrthoDB" id="288942at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonyl/alanyl tRNA synthetase SAD" evidence="1">
        <location>
            <begin position="35"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="9033" checksum="CA73DC4B5C50932D" modified="2023-09-13" version="1">MPVEIDWWTAEDFKANGLERLTPDPSFLMGGETEFRVVKIVGAEVYPCGGTHVGSTKLCGKTTVRKIGRSKGTSRVSYVVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF55</accession>
    <name>A0A9Q8LF55_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760623.1">
        <property type="nucleotide sequence ID" value="XM_047903082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF55"/>
    <dbReference type="GeneID" id="71983812"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03934"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="2">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="32070" checksum="8ACE09D85665ACE2" modified="2023-09-13" version="1">MSGTTALRIPGLFLTCVRYFELIQVARNPDSEIASCDLQLRGTELRLRRWGRAAGITDSASPELMTALEGFQEDEIKFAHDALEQIEAQLENAQRRSKPLIEGGSSLSSTPTATEHINDAQHTQEDFNESELDRALNKLRAQYGKSLRFGEDSQKKTKWALHDSTMLKNLISTTSAHLADLEKLFTKDIDRLVSTEVAEMMNLPDQGLALYLKVMAAIDPPLQQASKPKLASSGRTYQDIDADGEANSHIGRRLKEASERDGQGDVFQRMKFGGKSKSHVGDSVGYDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF56</accession>
    <name>A0A9Q8LF56_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inactive purple acid phosphatase 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760652.1">
        <property type="nucleotide sequence ID" value="XM_047904026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF56"/>
    <dbReference type="GeneID" id="71984756"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04878"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="49305" checksum="D379DD88088BA41D" modified="2023-09-13" version="1">MTFKYELLSQPSARRPPSLLHRYRFVIMLVTVLALVYLTTVCSGRALPFNVAKKSRWEPLRFDEDGNFQLAIFEDLHFGENAWDSWGPQQDLNSVRVLNDVLAAETQHLVILNGDLITGENQYKFNATSKIDQIVAPIVQRNLPWASTYGNHDSDFNLSRSDILAREQCYPNALTRSDVNAPNAGVSNYYLPVYPHNGGNVPCLILWSFDSRGGFLYQQRNATGAKVGQPNWVDQSVVDWFKTTNKRLTTRYNATIPSLAFVHIPTNASQALQTQAGVNPYYQPGINDDYPLAQQAQGYCPNGTNDGTCDYGGQDVPFMDAITSTPGLLALFSGHDHGDTWCYKWNHLLPGMSIKGNGVNICFGQHSGYGGYGSWTRGARQVRVSEEGLREGKVETWIRLETGGVVGSVELNATYGEDRYPATLNTNSSCGSCNYSRVTPMPGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF62</accession>
    <name>A0A9Q8LF62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-regulated protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759929.1">
        <property type="nucleotide sequence ID" value="XM_047907890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF62"/>
    <dbReference type="GeneID" id="71988620"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08742"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF11">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040463363" evidence="1">
        <location>
            <begin position="17"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="2">
        <location>
            <begin position="19"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="409" mass="45096" checksum="3AC0720AEB0A9941" modified="2023-09-13" version="1">MLFCVLILLMLHMASALKNVVVVGGSYVGINAARELMSIIPASHRVLLVEPHTHFNHVFTFPRFAILPGYEQKAFVPYNGVFTPSSRHSTVAARATHVHPDHLVIDKKWNGSNKIPFDYLVLATGTRLAAPSMMPYDDDASSVKYLQAYQSQLAASTSVAIIGGGAVGVQMALDLKEIYPEKRVTLVHSRENLMHQFHSDFHNILKDAFEEKGIELITQARAKVPEGGFRNDGETVDVELTNGQRVSAEFVILATGQRPNNGMIQSLATKNPDGLINPANGFIRINKTLQIQDDQYPNIFAVGDIADTGLHKAARPGAAQAKVVASNILSLIEGQKATAEYQNSPRAIHLSMGLKRNIVFRNPDEASGNTQPMIKEKFDGREDMNVEGMWERLNVAIRKPVEQEIRAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGD4</accession>
    <name>A0A9Q8LGD4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05192</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761297.1">
        <property type="nucleotide sequence ID" value="XM_047904340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGD4"/>
    <dbReference type="GeneID" id="71985070"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05192"/>
    <dbReference type="OMA" id="PGIITMV"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF567">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="57"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="482" mass="52537" checksum="A7B3B7ECF592B82E" modified="2023-09-13" version="1">MASFEYNTGADLEKKVSAINVAPIDPTTELPIYDDSSIDTITALVHEDHQHDIKLRTMSWQKAAWLLAGDQVCLAIMAQSWSLSVLGWVPGIITMLVAGILFYVTSMTMHKFIMKHPRIKDICDFGYHAFGKSNIAYHFTAFMLLANNILLIGFHVLTGAKVLNTLSDHSMCTVIFSVITALIGIVMSLPRTLKHVSFMSMFSAAAMGIAILLFLVFAGIEDAPYYGYNGNFPEDGLVKTYAFPPAGTTWVACMNAVLNITFLWVPQILFPTFIAEMEKPQDFPKALAVLAGISAFLFIVPPAIGFHYLGQYATAPAFGSLGVVAYKKASCAFVIVPTLVIGVIYANVSAKFVYGRIMGNSRHGHSNTVIGWGVWGGVMAAIWLVAFVFAEVIPSMGDFLSLLGAAFDSFFGFIFFAVAYYHLYKGKLFAGPLRSTMTVVHVVIMICGLFLLGPGLYAAVKAIMADYATTTRPAFSCKNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHA1</accession>
    <name>A0A9Q8LHA1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent monooxygenase sdcF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761777.1">
        <property type="nucleotide sequence ID" value="XM_047905057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHA1"/>
    <dbReference type="GeneID" id="71985787"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05909"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="17193" checksum="37EE0FB4D2C74DAB" modified="2023-09-13" version="1">MLALLDIFDEAMTYLFHQIPHFSGLMAFQPLHPIMTSRSAATGGNVLGIGPEDGYVVNADPNMQWAGAENDVLVKEVWEKAFAERQRLAEEHGVATDWLYLNYAEKWQDPIKGYGKDNVEFMRKVSRKYDPKGVFQRQLSGGFKLWNHGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ7</accession>
    <name>A0A9Q8LHQ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxylase/desaturase CTB9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761988.1">
        <property type="nucleotide sequence ID" value="XM_047905692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHQ7"/>
    <dbReference type="GeneID" id="71986422"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06544"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="322" mass="36049" checksum="6800E1E1C8B509FA" modified="2023-09-13" version="1">MEPTSIIATINYWRPPPPGEAEQPFGVTTAGHRRRKYNPQPTKIYNLRGREHEFDLDKNGFQFVTDCPSRERRWDDEARMREHVYPEIDALLKKVTGATHCYSMGHVIRRFSIADGLAAQEGKADNEIVTLTTPATVANVASAAVANAHPDQSYNGAKYVLDNIISTLPDRAVAADLAAKAKGNNRWATINAWRPLGLVTREPLAVCDAASMEESDLRAAPVQHNNPTVADGDANPPQCKDEKWQVAANPQQKWYWPNAMTEREVLLVKCFDSRRDGRARRTPHSTIQTLGDCRPVRERIEVRWLVFWEGVDAEGGDEGVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIF5</accession>
    <name>A0A9Q8LIF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762339.1">
        <property type="nucleotide sequence ID" value="XM_047905237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIF5"/>
    <dbReference type="GeneID" id="71985967"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06089"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="20196" checksum="C0DCA1F562636511" modified="2023-09-13" version="1">MPRQPPGPVEFIDDTSNPFLFNGIQRPGWVYQTLKKDDMVYGVGFGWCSIVRHSRHPPDELAEYISSEQAKCHDLEREAASTPGRDNEDEVWTIMARAALAEHRIKQVMECLSWDCNLKVWMNKNDEVLYDEEGYDITNVAKEAWREVWEALEKVMGKNGDLVKVMEEMSGKKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ46</accession>
    <name>A0A9Q8LJ46_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762708.1">
        <property type="nucleotide sequence ID" value="XM_047905469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ46"/>
    <dbReference type="GeneID" id="71986199"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06321"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF257">
        <property type="entry name" value="GLYOXYLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="40"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="5">
        <location>
            <begin position="109"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="34553" checksum="7B264252F5183F0F" modified="2023-09-13" version="1">MVGSRECLRNNYPFPLKQFSEGDRHKFIHFIRSDQASDCVAICRSNQYTHLTGKLDAEVLDSLRKSLKHVCNIGSGVDSIDVEACKIRGIQVSNTPALAAEAVAETVIFLIFGALRRVAVPLRTARKGQWQDDCPTGTLMSNKTIGLVGSGETASAVASRALAFGMKVQYCTRTESSPSLPGCTRIDFAELLRSSDIISLHVPLSPETRHILSKAEFEVMKPGVTIINTARGGVVDNQALLDAVREEKVWGVGLDVYDEEPHIPAEVREDERFFILPHVATKTHEIRGAMERVMIENLKAGVLRDGCDGVLQNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ81</accession>
    <name>A0A9Q8LJ81_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylamine N-acetyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762759.1">
        <property type="nucleotide sequence ID" value="XM_047905211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ81"/>
    <dbReference type="GeneID" id="71985941"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06063"/>
    <dbReference type="OMA" id="AYCFYEI"/>
    <dbReference type="OrthoDB" id="10260017at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2140.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053710">
        <property type="entry name" value="Arylamine_NAT_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786:SF0">
        <property type="entry name" value="ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="37836" checksum="579DBD0720523847" modified="2023-09-13" version="1">MALRHTYSPDELEEYFNRISLPYTRRVYHVSRLSDKEQLDFLNLLQKHHICKVPWENLIQHYSWHRVVNVKPKHLFSKIVRQQGRGGYCMEVNYFYHLILYSLGFNVYMCGSRIFSPGSNTFGGWTHVVNLVTVGEQKYLLNGGFGGNGPPCPVPLAHDEIQSQIAPAEMRLLHAPIPENLNQSRKLWIFQSRYDPSSDWSTCYCFPDFEFTPADITSMNFAPSHSPHSFFTHKVVAVRFSTEREINGPQGPGSPDEAALASPIDGAITLNHDVLTWRRKGRKVVEWPLRSEEERLHALEMFFGTTLSEEEREAILDTAAMVGARVMDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJJ5</accession>
    <name>A0A9Q8LJJ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate esterase family 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762164.1">
        <property type="nucleotide sequence ID" value="XM_047905673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJJ5"/>
    <dbReference type="GeneID" id="71986403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06525"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040126867" description="Carbohydrate esterase family 16 protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="18999" checksum="D5E5057C830F3E0F" modified="2023-09-13" version="1">MLLILPFLSTLTLVLATPHPYPPTPLPWHQTTHIIAFGDSYTYIQGLHGRQNYSFIGDQQNFSFNASTLLSNRIVQNQTATAEGGPNWLEFLTGCGVRRGLTDPRKCTRQLWDFAFADADISAEYAETPLHHEFTVSFVRQVEQFRLYGSPVLGGYRGEGGDFGGGVDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2S8</accession>
    <name>A0A9Q8P2S8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ABC transporter G family member</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_02091</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755377.1">
        <property type="nucleotide sequence ID" value="XM_047901239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2S8"/>
    <dbReference type="GeneID" id="71981969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02091"/>
    <dbReference type="OMA" id="FNCQLDA"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000702">
        <property type="entry name" value="ABC transporter (Adp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040454982" evidence="14">
        <location>
            <begin position="24"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="851"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="886"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="941"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="967"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1083"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="381"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="676"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="676"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="740"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO11011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122288" checksum="B02BCBBC17101315" modified="2023-09-13" version="1">MWRSVRVASLLALLSLPWDVIAGHQIHQYYTSNDDLLLQRDPFSIYEKRPEDCPPCFNCNLDDFKCMQYGNCTKSSGKCSCPPGFGGEDCSLPLCGSLADGKDRMPRQGNAPCQCDDGWEGINCNVCKTNQACNAMMPNGEDGVCYREGVVQKENFQICDITNRKILDMLKEKKPQATFSCNAERAECNFQFWVDQQESFYCALDTCSWDMKATDDRNTTTYRCENLKCSCVPDRMLCGAPNSIDLGDFLDQEIKGPAEFTSVSTDGGSDKDGSIFSEPAMNGLISSVFGDKSIFLKCNSGECLYKTEVPGYERPIKTINTPLIAGVISGCALFVVAVVLLVFFMSRRGSALGHRYGLIHLSDDEEEENARLLADHKPATLHFENVCYNLKGKQILTNIMGSVRPGELLAIMGASGAGKTSFLDILARKKKSGLVTGEFWLNGEKVADDDFRSVIGFVDQEDTMLPTLTVHETILDSALLRLPKTMSRAAKEQKVEDVERQLGIYNIRHQIIGSEETGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAFNVVESLVTLVKSYNRTVVFTIHQPRSNIVALFDQLLLLAQGRIVYSGPFRECQDYFDTVGYSCPPGFNIADYLVDLTMHATADLDADDFDDTNFNGEVDGRTTRASSTMAVKSIPSVSNVSIGESMGSGQTEPLLRPKGKRKTSIRQQQERQLFSRKSTEQQQQPPSSNHSASDGGFGDPESTRQQWLKLSKQQGAPPPQILDDPHSLPPATPGATGTNLDVLVTSYIQSEVASDLLSDIKSTISDANGSNGHAHGGPNGNTNGKLKGYAKPWIHTQFFILSRRTWRNLYRNPMLMLTHYAIAIVLAVFTGFLFYGLTDDLKGFQNRLGFFFFLLALFGFSTLTSLTVFAPERLLFLRERAKGYYHPLAYYLSKVVFDIVPLRLIPPLIMGCIVYPMTGLIPAWGEFFKFILFIVLFNLAAAMICLFIGIVVRNAGVANLLGVLVMLFSLLFGGFLLNHETIPKPLLWLQSLSIFHFGFEGLIVNEVRYLSLIDKKYGLDIEVPGSAILSSFGFNVLALWNDVVGLAVFCGVFLVLGYAAIHAFLVEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2Z2</accession>
    <name>A0A9Q8P2Z2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitogen-activated protein kinase kinae MKK2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755572.1">
        <property type="nucleotide sequence ID" value="XM_047901382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2Z2"/>
    <dbReference type="GeneID" id="71982112"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02234"/>
    <dbReference type="OMA" id="KMLEHPW"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06621">
        <property type="entry name" value="PKc_Pek1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000294">
        <property type="entry name" value="Map kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000263">
        <property type="entry name" value="MAP kinase skh1/pek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF5">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINAE MKK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="211"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="55382" checksum="39BFF40ABFABBB09" modified="2023-09-13" version="1">MASPVPLLRPPIPGQGRQQPGSRVPRLGLAIPASPGQRPVNSAAAPPMSENSALPPLSIPTRQQPPKLSLATPMGSSQTPQENAQTRRRGPPLQIAPGLSASGGSSDDSAHSRTNSFGANTTQNGSVSTTSSYSALNFVEMLRGDRDPQSATGSLYSSSSAHSGGEGMVRENSMQGMLPDLEKLSLEKGRPLDVEDLDDAGWKAAKKEGRIVEIGSLGEGAGGAVTRCILKGGKTVFALKVITTDPNPDVKKQIVRELSFNKSCASAHICKYYGAFMDDTSGTIGISMEFCEGGSLDSVYREVKKLGGRTGEKVLGKVAEGVLNGLTYLHGHRIIHRDIKPSNILLTRKGEVKLCDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITSDVWSLGVTLLEVAQHRFPFPADGTEMNPRAGLIDLLTYIVRQPIPKLKDEPENDLTWSPNFKYFIECCLEKDANRRATPWHILKHPWMVEMKQKRIDMTKFLKTVWDWQDEVEEPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3M4</accession>
    <name>A0A9Q8P3M4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cystinosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756277.1">
        <property type="nucleotide sequence ID" value="XM_047899569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3M4"/>
    <dbReference type="GeneID" id="71980299"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00421"/>
    <dbReference type="OMA" id="WIDVIYT"/>
    <dbReference type="OrthoDB" id="75720at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04193">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
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        </location>
    </feature>
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        <location>
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            <end position="110"/>
        </location>
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        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="32274" checksum="2F41962484981E4F" modified="2023-09-13" version="1">MFSDARHFAIIASWLLGWLYFLAWTTSFFPQAMLNMKRRTTQGLMPDFPLLNVFGFGCYTFSTAVFLFSQSIHDQYAARHPRSPEPTNRINDLAFGALGFTMSIVTYSQFWPRLWGWEQIPGVQRHASKVTLGLISGSVSALAIATLIVSVKGHPADGRGWAWIDVVYCTEYIKLVMTIFKYIPQVTSNFRRRSTIGWSIAQQLLDFTGGVGSLLQLVVDSSLQNDWSGLTGNPLKFGLANISLAFDVIFILQHFVLFGPVEEDELDKHIAIAGDRAGQEPLLPDRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P627</accession>
    <name>A0A9Q8P627_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P627"/>
    <dbReference type="GeneID" id="71987814"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07936"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="181" mass="20629" checksum="EEA9117EB4A78610" modified="2023-09-13" version="1">MTEKSPMLSEQHDQIRTDHTLQSVETYHTRAIWSGRVFAICTAAIVRYSLATTTTWFEFALTILKSIDSFTLVTFPVLVGLIVKYLLHSGLVLYVPVLDQEVVVVPQLSEEDLEAAGVDSWPAHKAEIRAWWKSVRSERGWRRFGADGWMAVLFLGGMVLMYSGMFWFEVKTLLKLRTGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6B4</accession>
    <name>A0A9Q8P6B4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759185.1">
        <property type="nucleotide sequence ID" value="XM_047907074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6B4"/>
    <dbReference type="GeneID" id="71987804"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07926"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="1">
        <location>
            <begin position="445"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="697" mass="78971" checksum="A5CBFCAA72363027" modified="2023-09-13" version="1">MSFPLPHKSGYYSDIVGRLLDHHPSLPHYAAIFRIVSDPHRSFANAARQLKHLARPEFDVTFTPHYNSFTFSGQLETARQLQDSKRWRAMLLNQRHADIPYVDTTAASRIPSDDQERHFQSLRTCKPWNLEGLDIIDSLKHVKGGLHLIMGPAATGKSMLNRALSLYFWCLGYHVLSISPANSKCDAVASGLTPAQLYAEFPDWNLSKFEFLRLFPSSRDIGVSKLSRKQAANTSVGHKGGEVLSFQEFLIALDEREQVQGTVKQYGVLQAMIVAAEMRRLAKMMRQKIGEADVDAWACLSELIDEHRQHAIKASDVAAHQRKKQDSDEETPVDWSHYEEAYRACKDHIISQSRYMITTSGNIHSKELIKNWYADADDGTKRVGVVILIDEAPKDQEINVWAGILCPRWAHAVRGVFLFGDEKQIGPTNTSTRQLNPYWDRLNLSLPLRLIREGYLVFRLREQYSIHAALADFPGQEIYDGNMRSADGMNKSLEVVKPGFREALLNIITREGQFELKASDHDLRLHWIQVYGSLVVQGNSRGSPSHVKVFFENIFPKLYDYFSSRGEKLSENVTIVCPYRCAKTLYQTKINELTAFPSQFTVDDMPRLETVDGGQGHSSFMAILDATFPDGDHLGFMTPARVNIAVTRATDVFWVLGGSLLCDREENKQSPLVKYRREMSKAGRVHALQEDAVGREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6P8</accession>
    <name>A0A9Q8P6P8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759605.1">
        <property type="nucleotide sequence ID" value="XM_047907375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6P8"/>
    <dbReference type="GeneID" id="71988105"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08227"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF30">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="672" mass="75068" checksum="74E6A82A7D078EC2" modified="2023-09-13" version="1">MPSFDSTPFAWESVEDIAECIHFDLLRFFLSCHLKDEHRAGMFSILNVAQDPGDRTASKSSADRACDQCKLRKVKCTMAKPCKPCEAKRISCTYDRARKKRGPAGKRMSMPGSFERPASVSDLGLTSPPLQPLERVTTAPVHQQTPQWPAQDVNGEATSCSATVSTHQSAERVRTMIQQEQLTPDAMSAASIGFSDHGVPAASPNAFIFPSMPVESPSGWDDPFAEITEQDLPALVESTDIWPAKVNETALLTWIDVYFKRLHPTIPILNRTTMYCDMLLRKHRTNAQYGAMLQIHERASMPSRSVQARMLMDECVKMRSSADFGEYPTIEMVLASFFLFACLFGSSQHKAARHRLREAVDLAHSLGLHLPTSYAGLSDTVREQWVRTYLVLSVTERAYALQQNPAISFRGQPGVTARFMQAFDPSATSEYIASLIFREQTDAVGMTGLLYLMDSFDAIDERITDCWSGYCSYSDGMCETFDRRRALQMFRAQRRVREACISGNISFAPTVTPLPLAQLLETQRADISVTQLWLLNRLWQLCLTHQLLRDVSEHSELRYDFACEIASALLDCCNKLTLAAMEVHGVGFAEKIFDVGIGWVTALQSSSQLRVDTAWSRAEDDSVPGSHDSQAPIKVAELPERLRALLQDFRGGDHQYVSRLDVALSGVSSYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6V8</accession>
    <name>A0A9Q8P6V8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759608.1">
        <property type="nucleotide sequence ID" value="XM_047907227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6V8"/>
    <dbReference type="GeneID" id="71987957"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08079"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14276" checksum="CEB8A84E1E96A60A" modified="2023-09-13" version="1">MDVFVSATFDQRAKDLMLEWHVPGMSLAVVTGDDVASKGFRHASIKPSKPCTPDTIFDIASCSKSLTAASVALLIADNDHFKDITIEDVLSHRTGLPSHDSSYVGIKAEHPDLAKSVTRNLRNLEINGDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P774</accession>
    <name>A0A9Q8P774_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759968.1">
        <property type="nucleotide sequence ID" value="XM_047907914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P774"/>
    <dbReference type="GeneID" id="71988644"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08766"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64518">
        <property type="entry name" value="Phase 1 flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040418996" evidence="1">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="149" mass="14991" checksum="DB80CD1C744A5E93" modified="2023-09-13" version="1">MKFAAVSLALLGASAVQGLATPATFGNAVQARQISGGINGIGAIVITLEDVIDSLIGLTTETIGAVSDAVNSAIGTATDAIGEITDALPTVSKRQADAAVVLARLNALIDRLQVQASILTGTALSTVNNLINQIQLIITSLTLDATTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7C1</accession>
    <name>A0A9Q8P7C1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low glucose sensor SNF3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760356.1">
        <property type="nucleotide sequence ID" value="XM_047903213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7C1"/>
    <dbReference type="GeneID" id="71983943"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04065"/>
    <dbReference type="OMA" id="HITRCIA"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="12"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="24578" checksum="26CA4EB0210176AF" modified="2023-09-13" version="1">MALPPKVYQVLVGVFAALGSFLYGYDLTIVAEVISSGSFLREFNPSTAELSLVASMLTAGAFFGASIAGLISDRFGRRWTIAVGGLDFCLGDGLQTGAESYAMVIAGRLIAGLAIGVLVMVVPIYQAELVHPDIRGFVTGLVQFMLGVGGIVSSWLSYGTYVSFSDDRQWRIPFGVQMVPAVIIATMIFLFLESPRYLISQGKTEEGLRTLVRLHANGDLKRSLGIGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7L9</accession>
    <name>A0A9Q8P7L9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS-type transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760625.1">
        <property type="nucleotide sequence ID" value="XM_047903266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7L9"/>
    <dbReference type="GeneID" id="71983996"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04118"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF27">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="504" mass="54116" checksum="F514977ED8052213" modified="2023-09-13" version="1">MATQTTIELQPMGREEQIAKTILPEIAESSERTLDSGPPSSSPPSTLDHEPPTPKLATSRAWIVITQLCGINFISSFSNGLLTIGLPEISRDLMIPSQLSLWPNSVFYLTAGSCLLLAGSIVDVIGPRRVNLPGALILGVFILACGLSRNAIDLVMFRALQGIANAMIMPRAVSIIFLAMPLGFAFGLVLGGVFQNGTGWGVGFYAGGATGLLFFLVSIWALSADLRLVSMEEVMKRLGTEIDWVGAGMASTALALFSYVLAHKILSADTSRIEDSETIGLLIFSISLLIGFPLWMQLQQKRGRPPLIPNHIWNNWSFTSVCLMILLANAVVNCMELFCSLFFQEVQLLSAIEASIRVLPQILVGTSLNFLTGVSVNTVPIMPAVVISSFCAFWAQILAPLAVDILFTVGTLVVSSAFPQRTQAMAGAVFSTFSQIGSSIGFCVTQVVSSSVTAESSFENKSSPQALMKGYRATFWTLFAWMIATCVIAGVGLRKVGKVGVQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P878</accession>
    <name>A0A9Q8P878_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04919</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761048.1">
        <property type="nucleotide sequence ID" value="XM_047904067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P878"/>
    <dbReference type="GeneID" id="71984797"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04919"/>
    <dbReference type="OMA" id="WEGFARI"/>
    <dbReference type="OrthoDB" id="4953at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000015">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000031">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="2">
        <location>
            <begin position="57"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="3">
        <location>
            <begin position="199"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1044" mass="116703" checksum="A167ACC9F0A31621" modified="2023-09-13" version="1">MPASKRQAPRFKTIQQLQLDYAPVNITQYESTRTGMRLAVVDKKGPKVEGEFALATEINDNSGAPHTLEHLVFMGSKSYKYTGLLDRLSSRAFSTTNAGTATDYTSYSLKTAGWEGFSQILPVYLEHLIVPTMTDPACYTEVHHIDGTGHDAGVVYSEMQARENTPSDLIELHRRVLMYPEGNGFRSETGGMTKELRALTADRIRAYHKEMYQPKNLRVIITGEVDHDELLQILDDFETTIVEDVPRLEDPFRRPWVDSKPTPKLTETKVDTIQFPEEDESMGELTVGWLGPNCDDALAVASLTVLLAYLADSPISVLENTLVEREQLCSAVYYEVETRPDIVTWFYLTSVETDQLRAVYERLIAVLNETLEKPLDMSYLSDCIKRERRQLKERAESSEDFFTQPLIEDHCFSDREGRALKDIETLSELDTLATWTEQQWKEALSKYFIDNHHVCVLGVPSKELSERSTKEEKDRVEAQKKRLGPEGLEKLSKKLEEAKAANGKPIPDELLEQFPVPRPELVPFISTTTARSGAARKMGALDNEIQHIIDKADDGSPLFIHFEHIPSNFVKIKLYMGTTGVPAELRPVLSLYLNNLFTTPVYIDGKRIEFEDLVTELEKDTISYYANSSYGNQQMVAITAMTEPESYAKVISRIRTVLFDAIHDPVRLHASLTKILADIPAEKRAGDSMVWAVNSMISSNRNANRHATNTLTKALHLKHLRKLLKQEPQAVIAKLQTLCDTLHRPENFRAVVIADITKLPDPVSAWQNLTKNLSTTNNLEPLDDLKSTISDVGNTPGTAAYIIPITAVDSSYIVLTSLGPNSYQHPDLPALIVAIAFLRAVEGPLWTSIRGTGLAYGASIRRSIELGKLHFSIDRAPNCFKAYAAGKAEIESYANGTKPLKKLAIQAAVGEIVYEMAEEGATMGYAADESFITQVLRGLDKDYNTQLLKQIGQVEPEDAKRAIEKWLVPLLSAETANMVVTCAAGMADDLVTNFKSVGFKVELKKLEDFQDDYGLKEPEGEDVKDDEDDDEDDEGESGSEGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8G5</accession>
    <name>A0A9Q8P8G5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tropomyosin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="18643" checksum="DF2DA9A0B98C1B3F" modified="2023-09-13" version="1">MDQIKKRMNALRIEADESAAKVEELSSKVKTLEQENLQKEQEITSLQHKNSVLEQEVEKFEKLHGEAKAAADESAQHGSQNDALQRKLQLLEEEAEENDKQLRETNEKLRQTDVKAGHYERKVQALEASRDQWETKYEEMAKKYADTKKELDDFVAEIGNI</sequence>
</entry>
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        <location>
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            <begin position="21"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="UJO17683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="13023" checksum="EE992205DB1BB0FB" modified="2023-09-13" version="1">MQYKSIAAAFALFAAAAAMAIPAAAPAGVGALEARNWNWKQQYPDVKNWVAYKKPDGTWCEPYTEQYSYSYAYSVSSFVSYSYNTNHPKARNWDWKQQYPDVKSWLAYPKDNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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                <person name="Stergiopoulos I."/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="46997" checksum="630AD6D8C9623595" modified="2023-09-13" version="1">MATSPHLLTLPPEIREEIYRLILNPDVNRLHHEDEYTSYRYTPSFVLFHINKQIYHESRKIFRELNTFVRIDTPWPEAQNHVAIEGHVPIIVSGEGAVGFKDHSLNVGIDAPGHGSVDWETQCFIILLEDLDKFTQMWYYADLTHPGLNEHLRLKLQLRDPYAVEWEEKRMPRALQQRLLLPFGKVKGLYGTVFADVDKGVKPFTKIEKEMREVQARPHESPEHCLREATRFKFEGNTELKEGRYEAALEKYKQSWTAMHVVVKGRQRFIHADHFFGREMREEPYCGKNGQSERLLLRVQLVANTCQVYLKQEEWELCRHWGMRSISMLREAMGVDETMTLSPEAEAVTSFPAAAEMGKIYYRTAVAWKMLDEKSEARRLLRVAKIYLPNDKSVDREIAAVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P989</accession>
    <name>A0A9Q8P989_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
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    <gene>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">Race5_Kim</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71986190"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:steroid metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Diminuto-like"/>
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        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1"/>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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        </source>
    </evidence>
    <sequence length="530" mass="59666" checksum="088B20639A49E430" modified="2023-09-13" version="1">MAATKLAEEHDAAVKRIASQVEKFHNEKKHFRIYHGSTSSTRPMQFTKDAIVDTSDMHRIFPVDKETMTVKAEPNVSMDVLAAHTIAAGYVPKIVMEFKGITCGGGFAGMSGESSMYRYGLFGNTVSEIEIVLGDGTLEYANREKNADLLQEAHGSLGTFGIITLVTIELLPAKSHVQVQIKPVSEPLTVPAIFEEACSDPTIEYIDGIYFNRRSAVVMFGKMIDYAQRDSRAPLLTTKQVHWFADTIEAHLKKHNNKISMLTNAETKGKVAANGATNGSTNGHANGESNGTTKIADIPPVILTLTDYLFRYDHGAFWGGKLAFKHFHVPQNRITRRLADPFLDSRTCYMALHKTGLADEYVVQDFGIPASTVTQFIEFVAQEMPECQIFLCPLKPAQEIGIDMRFNGDVIGSVREQRIFGVGVYGRGPRNSEEFYELNRELELKASVLLGSKLLYARTYYTAEEFWTIYNKERYDEHRKKWKAETLPSVYDKLHADMNYTRPRRSVRGILETIWDVKVAKRSDYLLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9C3</accession>
    <name>A0A9Q8P9C3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AtrR-like"/>
    </dbReference>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="671" mass="74344" checksum="B2E74F10F3014316" modified="2023-09-13" version="1">MPARLAACDPCRISRVACDHVRPVCSRCHKENNVEGCVYRDRPFKRRRRSENASPRPPSTPATARPDSNSTSPAFVERPLALPVHAYPNPGFLGDSSHTAIFEQIVASHESSEVHTPTTPGIVTAHLAQGRQASQGPQLLRGSALLDSLRSTLRPSSCANLLKAWSWKGTNLALAGDLLRPCIDTVVRVLSSQCPSIDVSQKLLTNSLVALKADSTYDVSRYRSQFVNDNIRWESLGLFLVAISRAATDLDEYGELYRTQPDRRKWQTTALELSDQCLEICLSLDCLNDLQLLLQYENWIAHSMVDGDQSYHSWRKLGDVISSLFALGYHERIDTEGQLPAFLKDLRSTALARTFSGDKNVSIFLGRPPRIHSNYCEVKSVITSIAPPSACEQLPEQGGDIRFSYALESWWTASCALLKEQILDGPRNRGYEQRLGIARDVQAQAEQLWQSLPSRFRLEGPLRLCDKFSPVERDFLASAKLNYLHVHFLIHLTLTQCTPEPDVELLGVAVQILNLTVEATVLKSHVENSGTGHVWKVAYYGLPAAGIICLCLLNRRLGTHNGGIPVFQTIQDLGVLVAHTETGALIHVDEPNYSLLAAATGTVKSLLEKTLSGTITQPYQVHSRPLETPAPPDWAPWSAEQGGWDFELDFWLNLADHPELSSNPTHNFAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9N3</accession>
    <name>A0A9Q8P9N3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762709.1">
        <property type="nucleotide sequence ID" value="XM_047905468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9N3"/>
    <dbReference type="GeneID" id="71986198"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06320"/>
    <dbReference type="OMA" id="PVISYWS"/>
    <dbReference type="OrthoDB" id="3942062at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="556"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="643" mass="70332" checksum="C6BA6EAA601CEA54" modified="2023-09-13" version="1">MSDDGRSDSSSEGEDLTTTGLIATRAKRATAGNLYATLRANLDDEELQKELLAEDEDDQGEYEASDKDDDDAAMESSSDEEDAGPPKEGDKEDLEGEKALKRAERAEAKKKRKMEEAKMRVPAFARAKKRVKLADDVKADDGSAPKKPKKKSERSDWRPTGADAPIRQSSRAAAVANREVVHANLKESLVRSEKQKKVMANHHAREQFKKRMELSQEERLAKTARIEKETAREFGRWEREEAERQRLRDEALAAKRNRGLDGPVIKYWSGSVLWEGDKIKRKRLHGSINVDDISDEPTKTGEASSINGNELNNALANFTAGKLTDTAPTSMSGSGPGTPGLTAPKNVAPAVTEAPSQPASQQQAQAIQAPPQAHWLDGIEQYASDQPEAVLTATLAQTAPMPLQPNPYTPSAPSINAAPVQHPPLQPISPYPPPAAAQNDPLHPSTTQSYHAWPSGFQGSNTNRPQLPYATAPPPPPLPKEQARRSLIILEQFEHLELSTVGRRSTSKASKDATTDPTPVASTLLPESYPTLTPDETRYLVNKKWKKEFPPAPEKTKCALTAWPAKFRDPKTGLPYADLQQYKMIQRLLMGGCQWSSFLGAWVGPSYGDTGRPAKGVPDGFGVPIEEAVVRQGSVGDTKMEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9P2</accession>
    <name>A0A9Q8P9P2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptojanin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762861.1">
        <property type="nucleotide sequence ID" value="XM_047905785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9P2"/>
    <dbReference type="GeneID" id="71986515"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06637"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048869">
        <property type="entry name" value="OCRL-1_2_ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF300">
        <property type="entry name" value="TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21310">
        <property type="entry name" value="OCRL-like_ASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
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</entry>
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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</entry>
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        <property type="project" value="InterPro"/>
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        </source>
    </evidence>
    <sequence length="2367" mass="261897" checksum="4643F4956091ED8E" modified="2023-09-13" version="1">MAPSTNKRKRPDRQASEDDVSGRPSPYRPEKSRTSRRTSQGKLATDEAESGRETESAAPEIRKSTEHHATSEPPANPPIRAATTTSRDGIETPAPASQRAPDASSEMNGNGVSDVVMKDRTTAKPSSPYRYQHVTCDLVASWAEAGSKSVVELARAADEMQLSDIMLELVRSALEGRLSGKHSGLAIREIISARKDDGLDVDFLAINTISFLYDASYKGAVLRELVASTGLDQQVMREELDIPLLQELGLVRITFDKMRTRKTTNALYRQANFNLLREESEGYAKLLTEFFSTAQEASNRPDDNPYIAEDAFQRVLALVGAFDLDVGRVLDITMDISASLLVKAYPFFVKFYRASSWWPQNEMLDNIKFDDQGFGSLPEWAFPRSGRTQRSDDDKAEVAKLTNSRDVLFWQRVKSVGMDAFFELGARKITNYDEVLPLLEFEAKPEVDSRGKEPDPHKRLRLNQDRKFMRDTRILPPPGNYDAAQLLGFKLRFYSSSARSRKDELPDNLIFLAALLIKIGFISLRDLYPHLHPSDEDMPKEKARLEKLKAEKEAKERPGGGMNALLMAGALADEGPPPRRMDKERSGAATPAQDKKAESKADEELPAPRNQKLVLLKGLLAIGALPEALHILGRFPWLAEFDYDLPQYIHRLGRHMLSKFAEFLQPLGDRPAIQNLRKQLFDTTAGADGTLVFTDRPAKRAIRHMYCDFVSKDDGNEYRHYYQDWSDNVPVCQTIEDVFLLCDTLLGYLGANVGQDVMLYGTLLRLAHQSLTTDRSENNRSRWLKLMKRLLVPALSCGKHNVQLSHQVFDLLCFWPTEIRYNVYAEWFTGATSRRPEVRTAFARNKAEVRDVLRRVSNDTSKRQSRALGKVALAAPGIVTMEVVSQIQSYSNMIPSLVECTKYFSPLAYDVLSWTLISSMSGAGQSRIQADGMLTSSWLSALSQFVAVLYSRQAHLNISPMLQYLASEFRVGDSKDLGMFEEILKEMAGIRPDMDINDAQVLAMAGGETLQIQILSQLSDRRHEKKGSAQRLVKALKGPGLIGQILVAIAQEQQMNAHHQSSRFMPLKVLGWNVDKVQACFQQYLEVLRYTLTAEEFEAAIPDATSLVRDYGIEPGTALTICRTALHHRMNATDAIIKQESSKQESDEKNGDIAMKDAAAVKEEIDNASGTPEPETGSVNTTDATATTSQPRPSPWHPVLEPIITNLTEHLPDLASRVSIPFYVTFWTLAHQDILMPMESYQKEVKRLDAEIIAIASDRSDVTAIVAKERDKRKRSLIDVREKLKQEPKQHLGAYMSVRNRISKKERHHWFARSDLANAAQRADLEAKHSALLQECFLPRAMLSPFDAFFSFQMLKILHDNGTTGFSLMHMLTQLFKKQQLTSIIFQCTEKESQNFGRFLCELLKLLMSWHADKATYEQEALGSTKKLPGFVKKWHEHGEPEVVMDWETYRRFIYNHHTCLSQALLSCFESKEYMHIRNGIIVLRSIWQVFPSVKHMGKNLIDHLERLNKEDDRNDIKVSAGTLFGFIKNGREKSWVLPQAFRLNDPAKDGPRAGSRATSARAETPQPSAGTPKLNASAAEFKPSPVTLVNGTGRKESAAGGPEDGEIEDEKPAKSKDGDVEMKDEATSVAKLTQKPSRGDVKAPSAARNTPRAESKPATPAPVDRRPPLSSSNSQRPDSSHQTPTVASRIEPVPSRPLPGQQSSRNSGRHGGRDDGYGRLERPSEARPGSRDQSPGHRSRGRTPPGAASRSYRDERPFDRPLERDARLPRDDARTISRRETPLQSRDRPQPVSRASDGGVHPDRMNHISSVVTADGQQGSRPSSRGTTTSEPPQQDGQVIVNPARLAMINADPSANASSPRRGREGLDTRRERDARPEERGPLRNDGRVRPPLDAPGRPEQQVDIAPTGPKRGRLREMGPPQSESSYGRLNASQDAPSGPRQSNGPPGRGGRNFTAPINTRNNDPPAASPTMSRPPDSPAAFRPPARQSSGSGQQFDRGSAHGSAPGTPASENGPAMHPSRAAAFGQVPPPINTSVAPNGPRNAAGSPTASAPSGPRGPGRAGLPSGTPTGPSPASAAPPSGPASANERQRRTERQRNSINATLQGTSNGAGPNGQGVNFRGASSRQPSFTAAPPNGPGSGPRSNVPTIASSMEPPLNRPQFDSRQSFDGPGNPQRQELFQSRQSDTPSRHREDDRSGRPRDSRDPSREPRRDNAGPMSQPPPPPPPGGPEDGRDRRGPRDDRRPRDQGIPRDGPARDSQQRHPERQPRGPGDMQGSFGGPPRPDWERGNEARGPRRDGPPDDGRRGGRMPGPNQDMRGPPRGPGAPDERREPSARGPRDDGAAQDRKRRHEETGGFDPKRRRSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAS1</accession>
    <name>A0A9Q8PAS1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763390.1">
        <property type="nucleotide sequence ID" value="XM_047906859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAS1"/>
    <dbReference type="GeneID" id="71987589"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07711"/>
    <dbReference type="OrthoDB" id="441660at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF8">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="190"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="709" mass="77923" checksum="BF8AC31AEAD9FF3E" modified="2023-09-13" version="1">MPQQKPQDEEQCVAVANGDSSAPRPVTPYRDSPPDSDSDSDSDSDSDSDSDSDSDSDSDSDSDDAPLRPRSEFHGLGRTAQPTWQDQISGRVPLRLKHVWRATVTWVKGPNPPRIYKITPIFPRIQHAPIELLGRYAPKRIQRFWLLIALYACWLFVFSLMLWRSAFAAEVPGYGTPARLSCGARYWGDKNGCGLNGDQCRPFANDTLAFRCPADCHKIQMLNPHAVGHQEVVYKPLVVGGPSDQDTGYEGLVENAVYRGDSFICASAVHSGFIPDSEGGCGVLTLTGEQGPFGSSKRHGIESTGFDSYFPLSIGFLKGTRAQCKDLRWPTLVPLVIFTVLLSLSTTDPGVHFWSLFVALFFHVALVSDPPANTTYYGLISIAFGRFLPACFCAWVTYKYTVKRSLTGLTAQIEKTVLWLGAAWVGSLNNYTFDRIPIQRLTPHDLKAQPGAVPALIIVVLAIFCIALGQAWAFRVEGRMPRYLVIYGLFVIALIICLIVPGLDLRIHHYILGLLLVPGTSFQNRPSLVYQGLLIGLFINGVARWGFASILETPASLLKGTQEGTLLPLVSVLAIGAKNITFNLGTLPAFDSKAKVAYDGISVLVNDVERFRGYGDDPSYGDSDSDWQPGQNLTWTWTRHEPRTGSSESDEATTQQDVDKLATPLPEYFRFGYMSGSRSGDYSKAGRWDGEGNWIPMASGPSLTGHDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAY5</accession>
    <name>A0A9Q8PAY5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_07130</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763463.1">
        <property type="nucleotide sequence ID" value="XM_047906278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAY5"/>
    <dbReference type="GeneID" id="71987008"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07130"/>
    <dbReference type="OMA" id="KHKIGLM"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="48"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="27946" checksum="669F8E69A2490596" modified="2023-09-13" version="1">MADKTEGKKSPLIRAPSQSLGPEYRPLEEKPKATVSTAPKIDNLHILPQTPQLIALLTMIRDKGTGRADFIFHSNRISRLLVEEALNHLPVQTKTITTPVGRTYAGVEFEGKICGVSIMRAGEAMEQALRECCRSVRIGKILIQRDEETSKPRLFYDKLPSDIKDRWVLLLDPMLATGGSALMAVDVLRSKGVPEDRILFLNLIASPEGVQNFAERFPKVRVVTAFVDEGLDEKNYIVPGLGDFGDRFFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBI9</accession>
    <name>A0A9Q8PBI9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 6B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763789.1">
        <property type="nucleotide sequence ID" value="XM_047905839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBI9"/>
    <dbReference type="GeneID" id="71986569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06691"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
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        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
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        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="30633" checksum="515D94414444CC7F" modified="2023-09-13" version="1">MLLRQPYTSPPPDARPDPVTIAMSKVPPSQADTEDLNNPKLNVSCLDFLLIELVPLAQRITDQLHAREQALVDEFKRSKIFHKDAVVANTPKGQERESNAPTVTVTDGTSASSVKDSSTADGMRSTALGAATVMDDETREAVFWRLDGLGYRVGQGLVERFSAGKPRPTTPLEAIKFICKDLWQLLFRKQIDNLKTNHRGVFVLTDSRFQPISRMSVDRRAGPKAAEDALRRAQIYLYFPRGVIRGALQGLGVDVTITAETTEIPSATFQIKTKGAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBQ7</accession>
    <name>A0A9Q8PBQ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763940.1">
        <property type="nucleotide sequence ID" value="XM_047909261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBQ7"/>
    <dbReference type="GeneID" id="71989991"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10113"/>
    <dbReference type="OMA" id="AEPRHKR"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15135" checksum="0BA97FED48C08966" modified="2023-09-13" version="1">MTTRGKRKAEDEVEELQELPEDDSAEEEEYQSDEEEYDEEGDDDDDDEEAPEAPPPKKARRTKEPAPADDDDEEGDDDDDADDQELDGEEEAAGDDDGDEDADDTAKSGGPAAAAKKNVGGAVPKEDDLKEVNDAEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBY4</accession>
    <name>A0A9Q8PBY4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Seipin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764019.1">
        <property type="nucleotide sequence ID" value="XM_047909486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBY4"/>
    <dbReference type="GeneID" id="71990216"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10338"/>
    <dbReference type="OMA" id="HSKQVQI"/>
    <dbReference type="OrthoDB" id="3990054at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="436" mass="48853" checksum="96F37407AA621B95" modified="2023-09-13" version="1">MSSRRSTKDAEDEPRGLIFSLIALVKDAILAPIRPFVSRTALRAYLATFLAVITAFILLGFAIAAYTLFYWQYIPRIGFERTIHLQFDSVYTNRITSHFPYGSANLGNEIMSGQGYDVVIELDMPRTKDNSEAGNFMVELNMYGSSSRSTAGMPQSGIAGTPTSLSENDALLLATSRRPAIMPYRSQWIDLIHKGIELPWYILCLRSESNTLRIPVFEEVNFAKGTKNAPASMRLEIQSTHRLQIYGAKALFRARFAFPSMKWAMYNHRLISAFIFISTFWMTELVFFGLAWGALALYLQQPDVGKIKAEEVGASSTAKKIKQEEEDDDVPAKLSDTERTFPTLSGQAPLRYSSPTEREIKREPDVEDETVVVPEAVARATDADVEDEDEDVDFFDSGIGTSLESSGPGRRDSVRRRRDRQGGGGTPVKQEVRDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDS6</accession>
    <name>A0A9Q8PDS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11313</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764994.1">
        <property type="nucleotide sequence ID" value="XM_047910461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDS6"/>
    <dbReference type="GeneID" id="71991191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11313"/>
    <dbReference type="OMA" id="HRYWIRV"/>
    <dbReference type="OrthoDB" id="434144at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032267">
        <property type="term" value="F:tRNA(Ile)-lysidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="7">
        <location>
            <begin position="35"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="558" mass="62739" checksum="2B86D64517E85DFB" modified="2023-09-13" version="1">MLNLISEQALATIVREVKHAISNLFPANVKPQRLGLAISGGVDSMALATLTNLIRKDPTFKHTFTAFIVDHKLRDGSAKEAASVTESLEPLGIEPQILRLDWTGHGDPRGLSNFESVARTLRYQALGKACAAHKIPHLIFGHHADDQAETVLSRAINGYTGLGLQGIAATAPIPECAGLHGVNRSGTPRLMGGSEGQLLPSHLEAWRPQPSRNRNAIIAVEDGGVSIHRPLLRYAKKELEGICRSAGVVWHEDPTNSDKTLTIRNSIRYLQLSDVLPEALRRSSLVQTAEEVRIKKEEVQRHAQMMFEKTPIELDLRSGKATVTLWTTLQDFGDMQHTYHVRAEFVRKLLLLVSPTAEVSLQHLDQCIEMVFAPVDAMRSAAKSVPRTIQIAGVSVTCAKSAQHAGLTIILQRQAPVRLARDSMQCVYSNSGWSEWLLWDHRYWIRVYVDVAASDPDTTMHMAFLSPDSLGQLRKRYKNMKPRASSLERALSLVPDRERWIVPALVSRMHNEDRIVALPSLHWRDLSWEMYETERPRQWEIRYKNIDFPKTAYHHLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC6</accession>
    <name>A0A9Q8PEC6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sensitive to high expression protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_11289</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SHE9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765276.1">
        <property type="nucleotide sequence ID" value="XM_047910437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC6"/>
    <dbReference type="GeneID" id="71991167"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11289"/>
    <dbReference type="OMA" id="ERYMALI"/>
    <dbReference type="OrthoDB" id="5595506at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="68"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="456" mass="50785" checksum="8D547C418E05C014" modified="2023-09-13" version="1">MDIVRPSARVGVEISRWASRDTRTAFSTATKAWTCVQCRSRLDARRTWGGNIEGAAVWKRQFSSTFRRLDDKSTETKRPIEPVTTTAEAETRLPKDKVETETHETSTPASSSTTLPSHTANKRSELSQRTSKILDSLLARASLASQHINQYTGTDYSGIEALRKEIIDQEQKVRSLHSEVEDSKSRHHEAYAKQTSAQREIVALLERKSSWSPSDLEKYMSLVRSEHLNDQDVQAAKDNLASAERSLEDARSLLERLERKQYHEEQIWSDTIRRNSTWVTFGLMGLNILLLLTQIAIFEPYRRKKIVREMQAALDERTLHANPAIEPKAAEKQAGNATPPSDATSETILAVTSSTSNEVVAKETLAAGEVLPAEATDVVAAIPTPSEVVQDVTPEYIAAPIGSKENTLEAWQEAFRDLFSERIVQLRKVDVTNTALQGAAAGVAVMGILFVLLRPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEE5</accession>
    <name>A0A9Q8PEE5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765357.1">
        <property type="nucleotide sequence ID" value="XM_047910343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEE5"/>
    <dbReference type="GeneID" id="71991073"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11195"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1140" mass="122600" checksum="D3BC2F601E91F3B5" modified="2023-09-13" version="1">MTGSKTTRKVYSAEQLHRLRGSQSQPKLQEAIEAKDSEDAEIVKEHVLRGSRSFAARSYRSRTSGNSLRVPSTKSNHENVPAEISEADDQPVGLQPPPNGLTMGDVVPNSQSLRPGPFRLRPSPTPSLKRKKAEAIVKAHGSPTHVRVTAGGRIVPSEQSPLCHPRFGYSAIQANGGLIKSVAPNHQAGKPQWTRATENGFVAQDIDGNLCQIVDGTIMPLQEVNGALQLYIEAPNVHGSSHGQLNAALAPHRPQQPTALRPASAVTPEPNIPSQIAALELEYAKLEHELKDVDKTEVIHGRGMGKGFKDGLVARRRELVINMDKIRKAIKALKNQPPPNAPTSPRAMAPQQSMSPPRRGPGGMGPSFHRPRPTQMFPGPIGPPPAPGPYLPPGAFAPQYTTPSPEEIYTGQRWDVPPPGMFMQPPPFDGSMGPPFQMMPPLASAPLANDLPPVTQAQQSGSIPQHDGSFADVSIETPNRSHAVSIRAPESKVTNMKSVLNPMSPAYKPAAMNAAPHGQFGAGTSMMGPSAPSFPVHLQRGTQRSSTATDDTISPAKKDVHMHSSSIASFNTADFFPRNTGEYSTRQQETHPSGRSEETHEPHEGYAARNKTTVTPGHEDFSPHRFRAPAVPPGTPVDSARKVSQPLNIPRQRNDVPDRDAHNVSPKSKREWLFIKECPGQTHTDADTSPAVHDGARSDIANVTNSFDTLDLLNKPRDWIEGFQAGLQRKQIGDRAGDSLNGYVAGLLKSTPATTASGSRAQTSSPMRPTSRRPSPALPSRSSSRLMMSDQANTARSPFEMSMQSMDTLKQAVYAPQNENAILTPAPDGPHVTGESRNLGAWAKDHNIQRMTDSNDSARITDVPNFPVPSRGSSVREHRDIKIKDMADGKQHPQMKDLPAIPGFNHIGDNSGTFLQPNAGQFSASLMPPTSPTLSTMSIASSSVAAGSVPNTGHRVTSISSMDSSMQRQWPGSRIMTPSEWKSASSVAHAAGLATGYFAHAQFDGSQDTKAPLRLPGQLAEMSDNVTKQNSQRVTSMTSTSSGPKHGRFHEGSLDGMSSPPMSPPRSVSPSMSPDVTPRATPRENGKKDSSPTKNPSPAKAFQSIAEKVGIKVATTTNGNPSGKRRWRDVWRKGGREGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEF3</accession>
    <name>A0A9Q8PEF3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765440.1">
        <property type="nucleotide sequence ID" value="XM_047909995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEF3"/>
    <dbReference type="GeneID" id="71990725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10847"/>
    <dbReference type="OrthoDB" id="3637007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="346"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="57845" checksum="D5BF64AFF28061C3" modified="2023-09-13" version="1">MAPPWRALLPTKQNFRAWRELLCGQRDVTIRVELQQPAPEIVRPQKPPAQIVVSNLTATQRPIRTSAGSASRPARIAKKTKRQARRPWERAEYLARLEQLIDGGDLVEATEETRNALSAQIAVMLASPEDEICNDEERLDFLVTEQQPADAELRQQWSALHGQAEEIIDAVKLDEGRNRPSILPDNFRDQLEKYEHARSALLKRKRVTPDLEGEIDAVNARLSMAEGKHNHRGWTATNDHSKRLKTRKEKLSRSRVVIDACCEHANGELRRLCKHHASRALQDMSGAAIDANPSAQPFVPQETVPWQRLPLEITEDYAALKELRYDLIAANVRYADRWVNGDYGYKAAWNEQRARVELELERETTDQDEEDFSRQWFQQNMSLLREVQDLETRYRESRGRAMLAGHEPSRDYSSIEGGWDHRSDGHTGSLASGHLRHNKSVINHGGWRSRFQPWVDALILPSKETGIAAAPADVWNDCSTVKLGETRSAPDLALGQGVLSHTRAGKARLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PET2</accession>
    <name>A0A9Q8PET2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765472.1">
        <property type="nucleotide sequence ID" value="XM_047910130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PET2"/>
    <dbReference type="GeneID" id="71990860"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10982"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040345225" evidence="1">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="156" mass="17137" checksum="0FB7AB94FDF74D72" modified="2023-09-13" version="1">MFQATLLLIPALTITIFIALTHSTPVINDPSHTAQPLSEGLTAQATAEGYNEYIPPRYVDIWMYEDTVCGKDSLERKRLLIQDLFYGTEPVRAGCYNLLPQYRSAWIKAMSAFCEVYAVSSTGCVGGEEGGKPLPSGEGRYMAEEGEGIVLFTVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PET6</accession>
    <name>A0A9Q8PET6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765534.1">
        <property type="nucleotide sequence ID" value="XM_047910787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PET6"/>
    <dbReference type="GeneID" id="71991517"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11639"/>
    <dbReference type="OMA" id="GPTECIG"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="275" mass="30892" checksum="9DC8727FE36EEC3F" modified="2023-09-13" version="1">MADMEKQPLLEQDTATAHPEPSLAELQQNIRTAQQAYWRKWSSTTSGKWHRRIMLSVTGLLTAFILFAMTIIAQDDFSDNDGAWSRDGRVPLEAHIMSKCPDAKDCLHDLVLPAMQQVGHQVDFKLSYIGSSTDHDDGVKCLHGPSECLGNVIELCAAKLYPDPKIYLGFTMCLTREYQKIPEQDLIDDCALEHGIETNRLKKCTTDDDGYLAVDNLRASFNRTAAAGVTKSCTIRLNNEVRCIRDGGKWTDCEGGHQVKDLVQDIRDLYDATYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEV4</accession>
    <name>A0A9Q8PEV4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765564.1">
        <property type="nucleotide sequence ID" value="XM_047909912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEV4"/>
    <dbReference type="GeneID" id="71990642"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10764"/>
    <dbReference type="OrthoDB" id="3946031at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035194">
        <property type="term" value="P:regulatory ncRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF322">
        <property type="entry name" value="HELICASE MOV-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="1">
        <location>
            <begin position="42"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="37894" checksum="AF025B36EFCAC3C3" modified="2023-09-13" version="1">MPLIGQQDLQLLVIAGDTKQLGPVVISATSRRNPHGNFLGASGLERLVALQKHLMHITAWTNYRSHPSLVVMPSALFYREQMKPADGLDWDTKLARDVLTLINGHRFRKAYRNISALSPDDRQRFVNVVSAARRDPATQSLVDVGGIVAILQLLRMLRDVGGVSLGRVGVISMYKDDVVTLRQRLEEDKMSNVDVEVTVDDEEGGSAEASTVDAFQGREKDVIIVHFVTTMPKQMGGVRHPFGFVRDPHRLNVATTRAKQVQILVGNYANWSEWCEGPKLSNGDQSLCRHMFGLMDYVETNGAIVDWAKVDYKLLARHPQYGLERQCCSTLMLSAVVAAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF93</accession>
    <name>A0A9Q8PF93_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome 9"/>
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        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="322" mass="37254" checksum="E7F6CB018791DA7A" modified="2023-09-13" version="1">MAPLIISSARGQSRAPKPRPPRLLVPDDVETITFLCPCARSQCRDILANLWITYHSSPPASLQKQATKKEIFVLTRRLCTNVVPEGIDNHKGTSWEPCQADATGLITRDIAQISIGETFLIAAQAIYLAHHRQLKAPCRCRRCRGLDRRPLLKLPAELRNKIYRLVLVFEKPISVRSSWRQPHLLRVNKQIREEASSIYYIENTFSITLSDFNCVPYRRFILRTDINRFYEKLPAVPQYEMWTTAMSWGNLEWWLFLYYRGQMPAIASTAGYHHLRMKVVPRAFKIVSQLRAEGMIRGRIHPVLLEFKEAVEEQANGAWVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFW7</accession>
    <name>A0A9Q8PFW7_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFW7"/>
    <dbReference type="GeneID" id="71989468"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09590"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="25764" checksum="75B298222BF3A75B" modified="2023-09-13" version="1">MRTDGVENVPPPLMANETPTEAASTPLLRSGAAKGHGIGVSAPTEENKPSPLLELPAELMNRIYEATLIAEESIWVKGRYTSPGLVAVNRQIRHEARTTSPWFATTSIQDGFTASSEATLHQMYLNDGLDLSVTTLRMDWNNLREWLQNFHELGILRLHPIQHADVDNSIVFYFFEDPEKVRRRKWNIVARSFDLVESMCDKLPWTDVLELLETYKVSVEGRAGADWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGW9</accession>
    <name>A0A9Q8PGW9_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Acyl-protein thioesterase 1</fullName>
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    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71989326"/>
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    <dbReference type="OrthoDB" id="2418081at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
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        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF63">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="26130" checksum="ED7EFA4B87AD8E65" modified="2023-09-13" version="1">MASSTVVQQSTKRHTHMVIFLHGRDSNATELASDIFESQGTDDKTFPETYENVKWVFPTAPETVSARFGGDLMSQWFDMWTTEQPHERQESQDLSKQVSRLHDIINEEATLIGYDNLFLAVISQGCAIGIQALLTQEHRLAGFLGLNSWILQEDKLRAKANATALSTPVSLCHTKDDDVINISYGQDLRDKLRDMGAQVTWCDCEDGGHWLNKPKGVDDVVAFVNKAMIRTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH45</accession>
    <name>A0A9Q8PH45_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766687.1">
        <property type="nucleotide sequence ID" value="XM_047908340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH45"/>
    <dbReference type="GeneID" id="71989070"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09192"/>
    <dbReference type="OrthoDB" id="10564373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="17130" checksum="761DBF06D287FB0F" modified="2023-09-13" version="1">MPARWEPAERHVVHVARSEFELPWKQIAMIFGDIFKVDWKGTALPKDSQLRQEYQGRKAKMWTQVIIKDEYTSEEKALRKVPADLLLVQHQFQPPPRALQALYLRPTLLRVIPPVIAKRMLDILRLRNIPTSSTSMPYRPNSQNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHA2</accession>
    <name>A0A9Q8PHA2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766766.1">
        <property type="nucleotide sequence ID" value="XM_047908304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHA2"/>
    <dbReference type="GeneID" id="71989034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09156"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF8">
        <property type="entry name" value="RICH PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="87"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="19742" checksum="C0A6D2747C662B22" modified="2023-09-13" version="1">MGALAGGAAGAFGAHKMGHGVLGGIGGAVAGSMLQDTYKKKHKKEKKHKQHGGRRGSSSSSSSSSSDSDSSHGKKKRHGATAALAGNFHASCRDVHLEGARLVAHACNTHGHHVRSDIDLNDCFTNTNGALHWAKGGNFAASARDMRLSEGGRVFEAELGDGRGGWRRNAVNLDERITNEDGRLMLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHF1</accession>
    <name>A0A9Q8PHF1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_12075</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767060.1">
        <property type="nucleotide sequence ID" value="XM_047911223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHF1"/>
    <dbReference type="GeneID" id="71991953"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12075"/>
    <dbReference type="OMA" id="SMGTFGE"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="12">
        <location>
            <begin position="45"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="13">
        <location>
            <begin position="312"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO22694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="46434" checksum="E7E6F90F64A66405" modified="2023-09-13" version="1">MASSALRRTFLSSSRTAMSPSQRLQAVQRQFSSSSRRPKEIQDAYIVSAVRTPCAIFNGSFSTVPAPELGATAIKEAIKRSDVPAEKFTHVYMGNVMQASVGQAPARQAAIFAGLSPSVEATTINKVCASGMKAVAIAAQQVELGQEEALIAGGMENMSRVPYYTPRGPQLPAFGNMTMEDGLMKDGLWDVYNQIHMGNCAENTAKKHDISREEQDEFAILSFKRAQEAWKRGDFAEEIVPVTVKTRKGETVVAEDEGYGRMKLDKVPTLKPAFQKQGGTVTAANSSSMNDGASALVITNKELAKQYGGGKRILAKIVAYADAAVDPIDFPVAPAKVVPIVLERAGITADQVKVWEFNEAFAAVIKANAKILGLGIDNVNPRGGAISLGHALGSSGARILVTLLHQLKKGEYGCAAICNGGGAASGMVVQLVDADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHV2</accession>
    <name>A0A9Q8PHV2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767080.1">
        <property type="nucleotide sequence ID" value="XM_047911241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHV2"/>
    <dbReference type="GeneID" id="71991971"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12093"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32209" checksum="6133812D05AE45E4" modified="2023-09-13" version="1">MVQVPHLPEELLQSVFSNFERTELYDWDERVKRQMLRSICLLNKQCYRVAQPMLFATVDIQEGSGAVGKLLQATVREPRLATLVRVLRIESWRGFDDERTISTEEAKYLQDTAVPAPDILPPVANVHPILGTDLAGQLLADAIEGSGDIFCEGERQIPCPVLPLNVLRDIRLTYALIDAKGLKNLLLSSPCVETLSIEWGDSCVGSCELRYDELGDAIRICHANRSLHNLKSLTLDDRAAQDFAREDLDDEVFPPLGDLRVLSILQTLDVPQSALVGVDESLDADTDDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHY3</accession>
    <name>A0A9Q8PHY3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminodeoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767166.1">
        <property type="nucleotide sequence ID" value="XM_047910986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHY3"/>
    <dbReference type="GeneID" id="71991716"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11838"/>
    <dbReference type="OMA" id="VWLSNGV"/>
    <dbReference type="OrthoDB" id="5288718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="295" mass="33944" checksum="16AD1CC184968525" modified="2023-09-13" version="1">MSGHFGVGPTSTDNEKPFVYTSIRYDRRLYHTAKNTAASCGKPCPFYMLEHHWTRLQVAKWSTFFFSDDRPRPNSGGPTIILQVLLNAVKDWHEKHPDENPEALRIKLCAYVGDKMRTEIYHPLKSIPMTGLFPTTFDLPVEQRRETEWSILLDTEPTEACEGTMFKTSDRSTYARARAAADIVNYMMPREVLLWDHDRNVIDGSICTVYLYRQGRWVTPSAAAGGLQGTTRRWALENQLAFEGEIPIDSMVDGEVVWLSNAVRGYFWAIYQSRDPPQDQPDEAVVQRIHHERFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI71</accession>
    <name>A0A9Q8PI71_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11779</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
            <location evidence="1 11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dynein light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767257.1">
        <property type="nucleotide sequence ID" value="XM_047910927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI71"/>
    <dbReference type="GeneID" id="71991657"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11779"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043935">
        <property type="term" value="P:sexual sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 11" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="100" mass="11636" checksum="84A7A19662D6BBF5" modified="2023-09-13" version="1">MADLKDNSSMKPEKLDAQIKSVDMSEDMQQEAIEVAQEAMDKFTIEKEIAHHIKRTFDERKGATWHCIVGRNFGSFVTHETKHFIYFYLGHCAILLFKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK98</accession>
    <name>A0A9Q8PK98_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768384.1">
        <property type="nucleotide sequence ID" value="XM_047912029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK98"/>
    <dbReference type="GeneID" id="71992759"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12881"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="71" mass="7636" checksum="73B95A7B66C880FA" modified="2023-09-13" version="1">MKQGGLAAPFCWYKARQQNVHGALEIGLPEERAKVNVPMPFISGDQDAVCLAKDILPVKEAGWIAARSGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKH2</accession>
    <name>A0A9Q8PKH2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768443.1">
        <property type="nucleotide sequence ID" value="XM_047912210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKH2"/>
    <dbReference type="GeneID" id="71992940"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13062"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="19365" checksum="5935894D6444D94F" modified="2023-09-13" version="1">MASSQNTCINMEPTTKTKIGFFDLPPELRHEIYSYLFVSRHDTVLTCFGQQPMYQGYAYRRLESYIPGYEDLRTIMFLKKARSLCHQMKCEVDEFFTSKHEFQGMMAHGATGTKGLRQCVSHHIWRQARHVDFEYYVEWGVLEVRSSRLTLTMDKQTGRWACRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKH4</accession>
    <name>A0A9Q8PKH4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768504.1">
        <property type="nucleotide sequence ID" value="XM_047912981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKH4"/>
    <dbReference type="GeneID" id="71993711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13833"/>
    <dbReference type="OrthoDB" id="3649915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="21887" checksum="36D9B377BAAE999E" modified="2023-09-13" version="1">MASFNFNHLTFPMQAVPQQSTLPYYHLTDCCDIRLSDIKNLLLMKRVPFKTAATHKRCTVLLNRAERGLMSYEDCTIEELQRFLQQRGFAREPPSQHTRLVRLLEKMDNRAKFERFLELPPELRNAVYGFHLGGLGVLQATKRERDSRSGSPVLVKRVVAPPLCLASKQLRQEAMLLFSGKRPLRSDMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PN39</accession>
    <name>A0A9Q8PN39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="149"/>
            <end position="172"/>
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        <location>
            <begin position="44"/>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="564" mass="63969" checksum="47BE590DA4062494" modified="2023-09-13" version="1">MAKHHRDRVQTLAIYRARLAARNDGIAPSQYEIEQYIRSKMRKSLERRETEEQPAEEQAEKKRIADTGAGTGMARDWNELRAEHNRHAVQEAQEQAEKKRIAGTTTTMSRMQVVDGPRDTIRPPMMRPQPHLQAHPPTNSWRGTMMRTLALLVPIYFAMVLVVTIACDWGLLEWDGMPPPMPKSLPMQLHSGLFSKTKAYGDTLPYFDNAQEELTHAHGSYCQTLEVACQLFPTPEHAAFYEHAVDVWTEKVPRSCPRPQACPNKVIEDRLERHELVSDWQEKMAQSALAVGENVRSGVEAGDSMLHHLVHGTDRVETALKDLHDTVSSKSKYASVTPYTTYTTLARLCRFHQIDQAYDQTTMDIALWPACRLLPFLIRRYHVVLTGDLTSPLWTPEWVPQMERALRSVLEEVQWVSQNVLASIDTMQTAGTNCHLTLGELERNAGKELTTSAKSLHRNLRRTCHALQGDTGLIKGLELAKARQRLQTVDTAIAKILAVSLIVPQPRWSDAQPWILVFDPTPYPATFDMALELWRSWTLVESNSNIRVTKGLASVAVSWGRLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQJ1</accession>
    <name>A0A9Q8UQJ1_PASFU</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14453" checksum="ACBE151C31BCC625" modified="2023-09-13" version="1">MQRRTLAIAGLPLGDTEVDPNDQQESPTSTDSGYQSRHGSKTKAQQARINRDRKAFIRALVQPSDFHSPEFQRLGIQPYYYQVYRGKIGPDYACQASCLEIATYGRSVALGIATISFLVTGAASKNDALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQN8</accession>
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10255" checksum="2833148AA8ECFE41" modified="2023-09-13" version="1">MAPKELNFITGNANKLAEVQAILSATPVKLQSQNIDLPELQGTIEEISTDKAKRAAEAINGPVLVEDTCLCFDAFNELPGPYVYTTSTLPFDLAD</sequence>
</entry>
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    <accession>A0A9Q8URE9</accession>
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    </organism>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71990215"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="241"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="425" mass="46219" checksum="C8EDF80DFE82212A" modified="2023-09-13" version="1">MTSFSLPRHSSCRSIDPLGLCEDVVDPGDGTLPHANLIEVLLKQADAELRDVEALPSFSRPTWTTIFSGLVEDIAYGLHLDSSLQTGGLEIVLKIEALADAELSKFRKSLISSAMSLEVAFPTRRLQQLCDEDQSISLRADQFDCLLAYLLLGTIHMPSGNTWGRPGYTQLFGGSEATAETSQAYLLTIMQHFSIEGYSSTLSSDHHFTFQLSSGMQMPELSISNIPAVAMPVTVLGPGPGGTQEERLVGQSPALALASLLTPELSPHAAVITSSVTVHSHWEGHGRDARMVQLYHTAARPCRRYIIADALELDGEDIISETSPRRIEREVRTLYAALSGAKACSLSEGWPLEDLRIEMPPWGCDAFGATLSVKAQCMMMAAGLAGLESQNLELLVPQDREHELVNIPRGRITISHLFSRLAVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URQ7</accession>
    <name>A0A9Q8URQ7_PASFU</name>
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        <name type="scientific">Passalora fulva</name>
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    <reference evidence="2" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764430.1">
        <property type="nucleotide sequence ID" value="XM_047909494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URQ7"/>
    <dbReference type="GeneID" id="71990224"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10346"/>
    <dbReference type="OMA" id="TPTRMKG"/>
    <dbReference type="OrthoDB" id="5424391at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="506" mass="57538" checksum="751D676A9B57AF3A" modified="2023-09-13" version="1">MPIAAIVGTTYQPAYWLTCHAVLCEDSAMFATYTPTRMKGTGVVQGLKSLAAKIHPQLPLNTKESNRLLTALTSSFRTHLDEAHPTAARPRVEHANDASTRHGGAGEPQSHSLHSSAAHADRHLASVLTNPLLAKGGQRFDYASAKRELIENPAKDPIQLLEEYHERNAATVRIAEVCLEHFMSGLTNMSAELRKAHILKSEPGRRVALWLLQNKVYEAANYIDNTLFQKLLVYFLHEEDKEQIVWDWISLDIRMPGSEGRTLRTKLKQELHNYRWRGRLLCALIYVKLGLLENRGSLPATNDRMHDALDVYFKACDLKLLGRQRKDHFEWTPLGAPAVALHRQLIQLPRPHPRVDLDVNRYNRFRDAIPLFLEGAPQIYFLAQYASLDLFHPRRQSPDRALQFWREILNDSPTASASAFVPRLKNGDGSAEIEQWFGLLARTVYVLQDEGRNQEASWLIGQALPLFPKQAPYMNKRLDEFRARDKTATSNQSQEHAVRVPFPTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URX6</accession>
    <name>A0A9Q8URX6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">CLAFUR5_10725</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="29" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 22">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764552.1">
        <property type="nucleotide sequence ID" value="XM_047909873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990603"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10725"/>
    <dbReference type="OMA" id="FPTLPDW"/>
    <dbReference type="OrthoDB" id="4251012at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2490:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 24" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 24" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 22 25" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="27">
        <location>
            <begin position="151"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="28">
        <location>
            <begin position="1104"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="1336"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="26">
        <location>
            <begin position="1347"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="23">
        <location>
            <position position="1289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1754"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1756"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1854"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1855"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="25">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="UJO20186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1868" mass="204941" checksum="997A848F8A3EF98E" modified="2023-09-13" version="1">MRPEVEQDLAHTLLVELLAYQFASPVRWIETQDVILGEKTTERIVEVGPADTLGGMAKRTLAAKYEAYDAARSVQRQILCYNKDAKDIYYDVDPVEDEPAPAAAPSAGNAAPAAAASAASSSAPAPAAAAPPAAAAAASSGPAAAVADAPVGAVDILRALVAQKLKKPLADIPLSKAIKDLVGGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGASMQATFNGQLGKQSSSLIARMVSSKMPGGFNITAVRKHLETKWGLGTGRQDGVLLLALTSEPASRLGSENDAKSWLDDTAQKYAANAGISLSTGPAAGEGGAAGGGMMMDPAAIDALTKDQRALFKQQLELFARYLKMDLRAGDKAAIATKRNEAALQAQLDLWNTEHGEFYAAGIEPSFSPLKARVYDSSWNWARQDALTMYYDIIFGRLKAVDREIVSRCILIMNRSNPSLLEFMQYHIDHCPTERGETYELAKELGQQLIENCRDVLGEAPVYKDVAMPTAPHLTISPRGDMDYEEQPRASVRKLEHYVREMAEGGKISEYGNRTKVQNDLQRVYKLIRQQHKLSKSSQLEIKSLYSNIVRSLSMNEGQIMPTENGKANGHIKKAGRNGRVNGAVKSGKVETVPFLHLKRKEEHGWEYSKKLTSVYLDGLEKAASGGVTYQGKHVLMTGAGAGSIGADVLQGLVSGGAKVIVTTSRFSREVTEYYQAMYARYGARGSQLVVVPFNQGSLQDVNALVDYIYDEKKGLGWDLDFIVPFAAIPENGREIDSIDSKSELAHRIMLTNLLRMLGAVKAQKATRGFETRPAQVILPLSPNHGTFGNDGLYSESKLALETLFNRWYSESWGNFLTICGAVIGWTRGTGLMGGNNIVAQGVEKYGVRTFSQQEMAFNLLGLMSPSIVNLCQQEPVFADLNGGLQFLPNLKDLMTRLRKEITETAEIRRAVTRETSVENKIINGEDSEAFYKTVKVDKRANLKFDFPKLPDWKSEVEPLNADLKGMVDLEKVVVVTGFSEVGPWGNSRTRWEMEAYGQFSLEGCVEMAWIMGLIKNHNGPLKGKSYSGWVDAKSGEPVDDKDIKAKYEKHILDHAGIRLIEPELFNGYDPNKKQLMQEIQIEEDLDPFESSKETAAEFKREHGEKVETFELESGEYQVRLKKGATLLIPKALRFDRLVAGQIPTGWDAKRYGVPDDIISQVDPVTLYVLVSTAECLLASGITDPYEFYKYVHISEVGNCIGSGIGGTTALRGMYKDRFLDKPLQKDILQESFINTMSAWINMLLISSTGPIRTPVGACATAVESIDIGYDCIVEGKARMCFVGGFDDFQEEGSYEFANMGATSNAKDEMARGRTPQEMSRPTTTTRNGFMESQGCGMQVIMDAQLALDMGVPIYGVLGFTATATDKIGRSVPAPGQGVLTTAREQPSKFPSPLLDIKYRKRQMDLRRKAIKNWQESELMYLQEEVAAMKQQSTEEFSESEYMADRAGHIEREARRQEKDALRQLGNNFWKQDSRIAPLRGALATWGLTIDDLDVASFHGTSTVANDKNESDVICQQMKHLGRKKGNALLGIFQKYLTGHPKGAAGAWMFNGCLQVLNTGLVPGNRNADNVDKVMEKFDYIVYPSQSIQTDGIKAFSVTSFGFGQKGAQAIGIHPKYLFATLDQTQFQTYKQKVEARQKKAYRYFHDGLINNTMFRAKSKSPYEDAQQSQVFLNPDARVSADKKSAEFTYPKKSPVKPTDKNTTEMVETLMKVNASANSNPGVDIESIDAIDITNDTFIERNFTPAEIAYCRKASSPQASFVGRWSAKEAIFKSLKVASQGAGQPMKEIEIVADESGAPQVTLHGQAKEAASKAGVKSTTVSISHSDAQVIAVAISAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USF6</accession>
    <name>A0A9Q8USF6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nonribisomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765091.1">
        <property type="nucleotide sequence ID" value="XM_047909923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USF6"/>
    <dbReference type="GeneID" id="71990653"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10775"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF3">
        <property type="entry name" value="SIDEROPHORE SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="21630" checksum="F959B8A61FDECB06" modified="2023-09-13" version="1">MSSFEVSTDAIRGEIADACNVLTEQIEDFYECTATQLGMFAESAKCDGAYQTLSVSSLESSIDQCRFCAALRHVYRANAVLRTRIVECSLGIVQAVIDEDLEIRRPTDGLEHYLQKEKKRHMWLGTLLGTVTIVERKLVCLTHHATRDDSALQFFMADVMRAYLNESAFPRAAFKDYVRHCSNIDKDASVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USN2</accession>
    <name>A0A9Q8USN2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tautomerase cis-CaaD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765332.1">
        <property type="nucleotide sequence ID" value="XM_047909950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USN2"/>
    <dbReference type="GeneID" id="71990680"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10802"/>
    <dbReference type="OMA" id="PMYHFEL"/>
    <dbReference type="OrthoDB" id="9981319at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028116">
        <property type="entry name" value="Cis-CaaD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14832">
        <property type="entry name" value="Tautomerase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase cis-CaaD-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="21278" checksum="D51EB49E70426976" modified="2023-09-13" version="1">MPLYEIQHICPLTPSQQDDLALAITRIHSTKFTTPKMFVNVKFTDATSHITYVGGKRRQGNHIIANVRAGPSRTQKDWDSLCHEIMSEWNRIVPMPKVKRSAPDEDHTLRSCILLGGIIGGYEAGFMIPPAGGDVQWIKDNWDEFKMKAESDEEFKEMVEEVEQRGMMNGAGKSTKEKLEEALGWGDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTI6</accession>
    <name>A0A9Q8UTI6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SLA1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766214.1">
        <property type="nucleotide sequence ID" value="XM_047908330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTI6"/>
    <dbReference type="GeneID" id="71989060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09182"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008092">
        <property type="term" value="F:cytoskeletal protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.700">
        <property type="entry name" value="SLA1 homology domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="SLA1 homology" evidence="3">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="508" mass="54151" checksum="CFAE2E93A5B2C38E" modified="2023-09-13" version="1">MTINKPGPPPHAACDTTMHTDVPSSHYISASETEDSIHTVSEYDSADESDAACDTPPETPPASPKLPRAAPQDLKEYPIRTWQDSTGYFRVEGCFVELRGGKSHIQKDDGTILALPIDKLAAQDGEYIESITSGQPVRSNLSEPVVGKATLPSASTLPTAPDGPLQASVEGSVLPVLPCASTMLLITVSRLLMLGTVGIAALLIFGPQNISYVDSCLQRLADLRHMSIILKVFFPSFAALALILGETDLLKSLANIRTQHRDLKDKRLYKTAPSAYTMESTLCQTLISSFLMRYFVGIWVAVIMLVVSVEILSMHSRGVLKQTLTQSIDFITKTSLSLGAFVARHSRAASRKIYSISKRTPALLYFILALVIAGLAMFAKGIMAGQRGSARGHTTTTDTRSISGGYGKDSTTVSTQAAAKTATNVKAVVGAKIASTAWIALDAKTVETVGPAVAPKIVGTVRTAADAKTVWDVWAVAGALTAWTATTALVAVVFEASPMPLDSVLERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTJ9</accession>
    <name>A0A9Q8UTJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766322.1">
        <property type="nucleotide sequence ID" value="XM_047908142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTJ9"/>
    <dbReference type="GeneID" id="71988872"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08994"/>
    <dbReference type="OMA" id="YDSCAVE"/>
    <dbReference type="OrthoDB" id="3653743at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="22101" checksum="FDC92F8F011505FB" modified="2023-09-13" version="1">MAQPHGTRPCFLLDLAPELRNMIYELILCDSSTALSPDSKPRVLIDKDTITQPPLLQTCLQIRAEASGIYYFGNRFDVVCLGFDPTDMILLTRQAKDITISVKVHDTQTAPKWANVFKWLQAYYNNEVGRLEEVWDAHCEAQQWNSVAKMFDMVDMLKNRQMPWREMEKVLEVTKDIAQLSVDWEWEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTY3</accession>
    <name>A0A9Q8UTY3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_09198</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766681.1">
        <property type="nucleotide sequence ID" value="XM_047908346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTY3"/>
    <dbReference type="GeneID" id="71989076"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09198"/>
    <dbReference type="OMA" id="AFFKCNV"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="627"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="350"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="595"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="888"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO22315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1048" mass="114643" checksum="E9C159874D050BB1" modified="2023-09-13" version="1">MSSPANRRSMRSSANNTPQRRSQHSSQAPASDPPVPDAEDDLPNSQTNGRANGSQRGTPRASQSQSQSQSQAPPTSSPLFFRSSPAGSQSQSQSQSLGVPANNVNGSSPLRQRQDATTPGVLSSEGGRTPRANGGIGDSSPIHYGTSSEAATPRANGLPNDPRSDSTGLFVRSGRSGPPSARDRRHDINSDVLESSGRRRQQFVDENGMPVQGDSDAATFSNLNPDTSDAAALGGRSTRFIWGTDVSITDSFSAMKDFLYNFQRKYRLIQDGEVMEGEDLNAGHPGLEKDYVNMLDTMLELGTKAFYLDCRNLKAYPATRKLWHQLQSFPSEIVPVMDTAVKDTLIELAEKKMGERRTQQSQQTPDRARHSSSMPPMPSSDVDNMGGETPRPAAQPVADEHDLVAEVEQNIYRTRPFGLDKTINLRDLNPGDMDQLVSIKGLVIRTTPIIPDMKDAFFRCSVCHHTVKVDIDRGKITEPTRCPREVCSASNSMQIVHNRSGFADKQVIKLQETPDSVPDGQTPHSVSLCAYDELVDTCKAGDRVEITGIFKCNQVRVNPRQRSVKNLFKTYVDCLHVQKTDKRRMGIDPSTIEEELSEQAAGNTEETRKVSEEEEAKIRATAARPDLYDLLSRSLAPSMHEMDDVKKGILLQLFGGTNKSFQKGGSPKYRGDINILLCGDPSTAKSKMLEYVHKIAPRGVYTSGKGSSAVGLTAYVTRDPETRSLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTVSIAKAGIITTLNARTSILASANPIGSKYNINLPVPQNIDLPPTLLSRFDLVYLVLDRIDESADRKLARHLVGMYLEDSPENANKDEILPIEFLTSYISYARANIHPTITQPAADALVKSYVAMRKLGEDIRAAERRITATTRQLESMIRLAEAHAKMRLSLTVEESDVNEAVRLIQSALKQAATDSRTGLIDMGLLTEGTSASERKRREDLKSGILGVLDEMLRAGGASARYGDVVRTLSEQSSVPVEGQEFAEAVRSLEQEGKVQIVGEGPRRSIRRVTGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUJ6</accession>
    <name>A0A9Q8UUJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767339.1">
        <property type="nucleotide sequence ID" value="XM_047911387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUJ6"/>
    <dbReference type="GeneID" id="71992117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12239"/>
    <dbReference type="OrthoDB" id="3927236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="40779" checksum="47BA7C4B1D8178ED" modified="2023-09-13" version="1">MPASRLVSLAKDKFGHDRVVANEYNAVTEIITGRYHLEEADPEVSADVQAGLANKGKTLEQIGYDPDKELAKINEQYQTEAEKARDNEKRTGRKRKRDQTSAEDGDIDLTDIANRLPKHPCSGLFCSNGFDWHDGNATPIIDEIMNSIEDHCSAHDGPITSKGRSRKGIKFSLTNEYLRVALQSIFKSGHRLRSRIEASLERFIRLNLDAFPEMRTRLKPLPCGPYDDTLKILPEKDGLALDLPLTVDKAEQTAEAIFDAVERRFKREAPESARFREPKGTSKKEKKRRKLTGTSKNVSLEEKYSLAPVKEDDDGKNFNFKDTLKACFAGPHGVLEALEVEVYRLAELEHKAFPELSGWPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUK4</accession>
    <name>A0A9Q8UUK4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-threo-3-deoxy-hexylosonate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767415.1">
        <property type="nucleotide sequence ID" value="XM_047911173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUK4"/>
    <dbReference type="GeneID" id="71991903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12025"/>
    <dbReference type="OMA" id="QEGIIQW"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF68">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="37123" checksum="49F2FA49495412D1" modified="2023-09-13" version="1">MVSSGAQASPPPKGIYCPVPTFFAKKGSSNYDPVSPPLDLETQSEHSLFLARGGIKGLVILGSTGEAIFVRNSERHELIKSQRKTLDDAGFKDRPIIAGTATQNIDDTIEMIKDSQAAGAEYAMVLGPAYFAPATGQAGLQKWFEVVADRSPIPILIYHYPGVTNGLYIAPSTFEKLAAHPNIVGTKLSHGIIDDQTLIASSPNIDHEHFYTFTGLGQNLLPVLTIGGVAAIDGLSGCFPRVVVRLFRMFNDSSAKGTTKQDINQMRELQFRICKGEKLIAAWGPVGMKEAIGRLWGMGDPKGNRLPLAGGFQDGEKEWAKWDKTFQGLKELEQKFESEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVN9</accession>
    <name>A0A9Q8UVN9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_13589</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RSP5/NEDD4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="9"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768542.1">
        <property type="nucleotide sequence ID" value="XM_047912737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVN9"/>
    <dbReference type="GeneID" id="71993467"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13589"/>
    <dbReference type="OMA" id="WKRPTLD"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072666">
        <property type="term" value="P:establishment of protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08382">
        <property type="entry name" value="C2_Smurf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000011">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000017">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000074">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000005">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="14">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="14">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="14">
        <location>
            <begin position="392"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="15">
        <location>
            <begin position="481"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="138"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="267"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="138"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10 11">
        <location>
            <position position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001569-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO24176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="814" mass="91447" checksum="552FB2822268E1C2" modified="2023-09-13" version="1">MELPSQPNLRVTIIAADGLYKRDVFRFPDPFAVATISGEQTRTTGVIKKTLNPYWNEAFDMRVTEESILAVQIFDQKKFKKKDQGFLGVVNVRIGSVIDMDAGGEEMITRDLRKSNDNLVVNGKLILNLSTNLRAPIANGNQASNSRPAGSSAGPSTNGAHTPSTPVGAQSSASLATPSVSTPGSAAVTRQNAASAAPNAAPAVNGNGAPPPGRNQSGFSAFEDAQGRLPNGWERREDNLGRTYYVDHNSRQTTWIRPTANFNAGEQAAQLQQQQNVERSRHQARMLPEDRTGANSPTLSDRNSPSHTPSVSGANNASAAQMVATGATTAGSGELPAGWEQRHTPEGRAYFVDHNTRTTTWVDPRRQQYIRMYGQSAAGNSTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKLIYFRSQPALRILSGQCHVKVRRTHIFEDSYAEIMRQSPNDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGINPEHLGYFKFIGRVVGLAIFHRRFLDAFFIGAFYKMILKKKVNLADMEGVDAEFHRTLTWAKENDITDVIYSTFSVEDERFGEKVTVDLKPGGRDIEVTNENKEEYIELITEWRIQKRVEEQFNAFVAGFHELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYTENDVVIQNFWKCIRSWDAEQKSRLLQFATGTSRIPVNGFKDLQGSDGPRRFTIEKSGEEAQLPKSHTCFNRLDLPPYKSYDALTQKLTWAVEETVGFGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY9</accession>
    <name>A0A9Q8UVY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768842.1">
        <property type="nucleotide sequence ID" value="XM_047912746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY9"/>
    <dbReference type="GeneID" id="71993476"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13598"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF479">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="93"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="550" mass="60353" checksum="4337794172E0BDC2" modified="2023-09-13" version="1">MSNYVKKTPDVSVEGLNDDHRPSATSKSESLSSSAISKDELPCPETAHRHGVPTYNDANQIEKAEATAPCSDPSPPSNGNDNPSSREDAKDKCGWRRSCCTMIAETLSLGILSLPAAAAAMGLIPTIVLLISFGFITTGTGYCYYLYKEKYPHIRSIPQALDNIFGAPGRWITDIIITVYLILLMAGHLILFSSFVQAFSKPEDVPCRIAVMGIAYFINCLFTFYRKFARLGYVCVACCFSILIATFVCLGYLAADKDKNLSLPGNYSAFAVTPLGLHYGDGKVTTIFGACAAFSNILLSYSGSICYFNIIDEMKEPRDFWKCLLVTNAATITMYTIAGIGMYALAGQLVGSPALDSAGSQGAKIAYCFGLPTILLAAVILANVNCKRTEDLIYAWRGLDAEEAHRSQRKAFSAVNVLWYAIVISWWTVSFIVGNSLPFFGPLLAVIGAISGNWICLGWPGMFMLHLWRPEVIQDDGTERKFTRQEIKEAGGWWKCYTTPNRWRKLLVPAMILLIVINIAASALGLYGSVMQFAVLGKGRKPFSCEYDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW06</accession>
    <name>A0A9Q8UW06_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768768.1">
        <property type="nucleotide sequence ID" value="XM_047912945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW06"/>
    <dbReference type="GeneID" id="71993675"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13797"/>
    <dbReference type="OrthoDB" id="6118920at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="236" mass="26227" checksum="AB12259EACC3BD1E" modified="2023-09-13" version="1">MNAINQKHKVRQWLACVLARSACSMQSACRDRRPQVVSTHLVCGQAAGLVLTLRGECGSSPIMSDMYCQNVFIVGPQRKESNGTERAPGVISEVSIKRTKISREQIASAPDPCLPSCKLNLKQKNAVHPVVYTKLLVGEDAVQDLLHTPHWQKLQQNMKAGLVFLCEAGCHWLVDDGIRLMPTSAEGWMKVDHTFRSMLGERAMAYTLVPKDLAVADRVELVLSLCERRADTPRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW24</accession>
    <name>A0A9Q8UW24_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GRF-like zinc ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768828.1">
        <property type="nucleotide sequence ID" value="XM_047913095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW24"/>
    <dbReference type="GeneID" id="71993825"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13947"/>
    <dbReference type="OrthoDB" id="4469945at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056444">
        <property type="entry name" value="Zn_ribbon_GRF_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23549">
        <property type="entry name" value="Zn_ribbon_GRF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRF-like zinc ribbon" evidence="2">
        <location>
            <begin position="153"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29666" checksum="A322979AC8C33FC5" modified="2023-09-13" version="1">MTKIKNMAPCDPDKQATQDQSQKPADVDSLAGAFEVVSLGDIFTPANSKAVSTIDDNESSKIKVETPEKASNIHSPLRLRGSPTAGDDKTKDDTVGDGKPVHVKVEKSKCVYTEIEKNKPVYTKAENNKPIPSSPPYYTPPTSPSGARLARKICRSCQTPAVKCITSIFNENGNAGRPYWACPNRQCEATKKSDFEKGWVSWGDSKGIDDKNPTCFCDVPSRQDRICKDGGKKGLGFWTCAEGECDYYSEDLFGVFNAEVTRYFWPWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWS9</accession>
    <name>A0A9Q8UWS9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carotenoid 9,10(9',10')-cleavage dioxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14252</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769578.1">
        <property type="nucleotide sequence ID" value="XM_047913400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWS9"/>
    <dbReference type="GeneID" id="71994130"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14252"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF89">
        <property type="entry name" value="CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="675"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO25212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="720" mass="80402" checksum="7F680B9242990176" modified="2023-09-13" version="1">MFDQPQSLRPASLKRKRTFSDNIERTPLPRHPYLTGNFAPIQQTLPLTPCTYGGVIPEELADSEYVRNGSNPVSNEDLGRDAHWFDGDGMLSGVSFTRDDETGHVTPEFVNQFVLTDLYLNTLSSPRLKVPILPSIATLVNPVASFIYVTLRILRTILLVILSHLPGSKQKIKKISVANTNLVFHDGRALATCESGPPMRIQLPGLETVGWYDGAEAEGEPKREVAGKETVLGQDGGLFSFMREWTTAHPKVDPLTKEMLMFHSSFAPPFVQYSIIPQSPHAELDSTPLRAYKARQDKILNAAVPGVKSAKMMHDFGVSSTHTVIMDLPLSLDPVNQLKGLPPVTYNSSKPSRFGVFPRRHPEKTQWFETDACCIFHIANTWDDSSSAGGVTGVNMLACRLTTATVIFAAGNIAPPVEKKQKVVAAARKRMPFFSKYDADREQTYYDHAVESPSDEKEPLLRIRSNSQPLADDDDLFNEDQCRLYYYHFDLQTKNITHQWALAAIPLEFPSVRPDVEMVQARYIYGCSTTTTDFGSALGKAAKIDALVKIDAGSLIARGKEHPPISVTGVVDSRSMAQILESEDLNDPIQVFRMPKGWFAQEPRFVPASTNVAEDDGWLLFYAFDESQLLTNGDVPKDSDPRARAKSELWILDARDMTTLVARVHLPQRVPYGLHGTWFSAEEVRGQRAVDSIRTTARALEARERGAWMRIRDWVERMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>Q9P407</accession>
    <name>Q9P407_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4 6">Ecp5</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Extracellular protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ecp5</name>
        <name evidence="2" type="synonym">Ecp5</name>
        <name evidence="6" type="ORF">CLAFUR5_03423</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2000-02" db="EMBL/GenBank/DDBJ databases">
            <title>Specific cell-death associated recognition of secreted proteins from a fungal pathogen occurs in host and non-host plants.</title>
            <authorList>
                <person name="Lauge R."/>
                <person name="Goodwin P.H.G."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Joosten M.H.A.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race 5</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>Allelic variation in the effector genes of the tomato pathogen Cladosporium fulvum indicates recombination and positive selection.</title>
            <authorList>
                <person name="Stergiopoulos I."/>
                <person name="De Kock M.J.D."/>
                <person name="Dupont R."/>
                <person name="Lindhout P."/>
                <person name="De Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2018-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Lucentini C.G."/>
                <person name="Medina R."/>
                <person name="Franco M.E."/>
                <person name="Saparrat M.C."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CIDEFI305</strain>
            <strain evidence="5">CIDEFI320</strain>
        </source>
    </reference>
    <reference evidence="6" key="4">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="5">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF104527">
        <property type="protein sequence ID" value="ABM47073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ271891">
        <property type="protein sequence ID" value="CAC01610.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK388031">
        <property type="protein sequence ID" value="QDX18283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK388034">
        <property type="protein sequence ID" value="QDX18285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q9P407"/>
    <dbReference type="OrthoDB" id="3922530at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010977737" evidence="1">
        <location>
            <begin position="20"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABM47073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAC01610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDX18283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDX18285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="12373" checksum="F55C0DA075E23D8C" modified="2000-10-01" version="1">MNTFTLLLATLPLLAYGRGDNKPGQFNYICEDIPCDEEGVDSWILQACIGIGGTELTAHGGIYDTTGELVGRTAICLCARGQTKAHDYNISGDYPPGVAHLTFDVRAPYWCQSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXP9</accession>
    <name>A0A1P8YXP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp10-3</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 10-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp10-3</name>
        <name evidence="3" type="ORF">CLAFUR5_03986</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943121">
        <property type="protein sequence ID" value="AQA29292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXP9"/>
    <dbReference type="OMA" id="CEWGDIG"/>
    <dbReference type="OrthoDB" id="10304076at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573458" evidence="1">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="77" mass="8601" checksum="A93AD820332CDC6D" modified="2017-04-12" version="1">MNFILLIVSMATLALASPPDWYYGKCNVEKQTCEWGDIGVTQWDCDPNALCSDDCNKCTIHRGKGNSNLANCQWPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4Q1</accession>
    <name>A0A9Q8L4Q1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mus7/MMS22 family-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755132.1">
        <property type="nucleotide sequence ID" value="XM_047900470.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71981200"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01322"/>
    <dbReference type="OrthoDB" id="2386201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035361">
        <property type="term" value="C:Cul8-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019021">
        <property type="entry name" value="Mms22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09462">
        <property type="entry name" value="Mus7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2190" mass="244052" checksum="8611DC9B3286B04C" modified="2023-09-13" version="1">MKRWQDRGVVEDSEDDEISLGAASPSPEPPRKRTKHDRDDALPDQQDDGLQISPTKQNDTPYETADHPWTGPKVAITYGQKTKTKPQNRPRTPEAPPRREYASPRVLISVESPHAERPPATQRFLFAEPQSPPDSDSDGLPDLGPVLRRPETPTQHALSAASSPLSERDVSPPAVFLPSTEPSRLEWTESESTRIDNAATGLLELGHIEGQVPTSTAAAKRNLRARKPNQLNPYQYDRALYVQQCKARGVQPIRLVEQELQEEESQSQSHNSTSQSQSTFHAASSPVDTRGIDALGPSDVPSDSVDRETPSGHRLPKRRRLEDRGSGAGLAASTEAQRGQREEFSVPPSPPRTGSDLSTSEEAPSGFRFPPRMTPIPLPTPQISSDMTRVEADDDSTPGSSPRRPRTSTLNRSRMKAPVVTVSSESEPESDLEAKRIRREQKRIRGVLPASWLKIDFRAQKPREVPAASTRQRSPSTSPERHQPQKGVAHRISRRSVPVDGCAFPIASGEENDSGTSVRSLARLKQRKLDANSTRLKLGQQSTFDDDVMENDFVDPMLAGPARSRGAKQSRGHQPRITQAFPEGLRTDFSEERSSRKQAPISRRHGIPKSTTRRRACASPPAPVRLSITDAFDDPEPGEAQLPSFVRLALRQTRHRHDRGRHSPTHKVVRLATADETEDASATLRAWRESAIVQRVGRQRTRSAGNGYMPFQGQAARVALAEISGNQRTLATYDSLDQGIRQLRPRELAGREEVIEELTSPQALRTVDGVETATKATSKRRLRSGMRPLRLRDAQLESLERCFDQNHRSAVFERRMQCMTEQVARRARQQGEANFHLERYLHTGNALDVIAGERMKAAHNPAEDVSRTQEVHQATSIPYRPRKRQARRLNVEAREYRQPSEPLPDIAITLEDEDEPYEAPRPVLQDLGPFGTRYSNSFDIRPLQSGTFFDQNTFVGSGELSDALALTQHDLNQQRGCMRVHLGAEILSWGVWQDEVAVHFVRIATSIGNTLGGHGSVLEQQASRLSSHEITEVASYLLRSVIRYLAQCVYFSDPIDRLTCVESISQLVTTLSETFVEHQSTADAAMAVTRIMQYSTILAKQALHLCDHSVIPAAMETGVKKLLLSIAQRLASHAVRNHVGELRSAYEDSHMSDHHETGFKDVVPTLSSMVILRNVLQDTSGLTVDFWAVARAFFNPENAATCSVKHLEKAWYDLFTILPALTFDSHGISRDNALSADTTAAWTLPQLLLKRVFDLYEASSAVRCASVNDYVRVLLSRCHSLVVTWGYWQSDLALSTIYDFFAQRNLHLLNSEEDRGSPSFLEDFGSEAFLQIQPDDRSFHIFLKILAASLKGMQSHSIPLRKIQSIVFRLTPNHARTYRKDATLVKADLEALRNHYDLLCTLYCAAPVGSRPSVYLLQNLVDHSSSHREACRASVRAWAHVAAFQAASDQSIDSLTSLIDWYSDMVNTTITQYRLAKSEAERDFEVAQSEALEAGSDMPFAILESTIANNQVQIAATLLDALAGLKRTLQSTSSVKTAKALVEGTGFMSTLELFDPAQRRLLSTMLEALAIVNAALDAESRPTNSVSQSEGSEDSQEFGDFDALQAFVEDDTGLEDDQVTLAGTFLAPIGHFLSNVFGADAAADDTLLMTTVDTWSRIAGCTSVAHRRSWHSYVDEYSSTSWNQMRDTSHKRKYTTYFLSRLVEQSKGSDDIKQAVLTTWLLSLVEREATLKFQHLLTATILEHWSNEPLLRNLPFASERDGSKYHITLTQLRERRVALVSSILCNMREHYNYSIRFSRSRSPELRSTYGIMLRQMMSVMKNYYQELQSTVNVEVADAGATGAYVNFVQQIVASLQQFTLDISPVDRFFLDSSAFPLPAGDPTYVVGRLRSYAPKLQESHGRAQLAVFVQSVMERALVDGQQDYLIDQMSTAMVGVDMLSCQLPTLWQVMSHSLLTVYISRSFETQSSWIAVVLLLQACIRAAPKIFYNIDIGDGAMVQAAITSLGSVLHSISQQVATVLSQSTLLDSAHALKVLGAMLMVGQASTTFIAFLEQSTAAGKELAAHLKVLRSQARALRTQLTSPERDHLMDLPAVAPSPDCIWQDTKNFTEKQLKETVETNWYSDGSAYFVRRGNTSKRLAVQLDSAEVGRNVLLQIIREFSNTYDATSDHRCRQRQARRQCDDILSKLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5N2</accession>
    <name>A0A9Q8L5N2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00575</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755628.1">
        <property type="nucleotide sequence ID" value="XM_047899723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5N2"/>
    <dbReference type="GeneID" id="71980453"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00575"/>
    <dbReference type="OMA" id="GYQKNDP"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="102" mass="11881" checksum="89186EFC2D9BD892" modified="2023-09-13" version="1">MPTPESESFKAAKPTVPPTFDGVDYDDNKALKAAQDAIIREQWVQSMMARLIREEMGKCYYKEGVNHLEKCGHLRERYLKQLKHSKVKGYLFEQQNYVPKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5P9</accession>
    <name>A0A9Q8L5P9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755665.1">
        <property type="nucleotide sequence ID" value="XM_047900196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5P9"/>
    <dbReference type="GeneID" id="71980926"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01048"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF105">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G08790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24502" checksum="7ABDF89A35EDD1BC" modified="2023-09-13" version="1">MTLKPCCGTGSSHTGTPKGRFEKKHRLDCYVAESNGAPKGIIVIIPDAFGIGLLNNQILADDYARHRSTVYLPEFIGANRRTATTLGAGVPAGVFDSISFVTHPSFLTFPTDIEATVLPNSYTTAEIDQQMSPEHAQKRKDILQAKTAKTKICLPSSRMTLLALVFGGNDQSIEHEVIMYEKVHHGFAVRADENDKLEAEAGKEAEGQAVRWFERWFTNPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L740</accession>
    <name>A0A9Q8L740_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase nit2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755789.1">
        <property type="nucleotide sequence ID" value="XM_047899683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L740"/>
    <dbReference type="GeneID" id="71980413"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00535"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF27">
        <property type="entry name" value="DEAMINATED GLUTATHIONE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="31118" checksum="D2F285FD38C7B4B1" modified="2023-09-13" version="1">MVIRYTNTSKMAIAAIGQITSTNSLHHNLSQCRLLLQIAVSAGAKALFLPEASDYIGTSAQESFSLCVPASESPFVLGLQEAAKQHSLPISVGIHEPSDDPGSKRIRNTLIWIDEAGIITHRYQKVHLFDSELENGPVIRESETIEPGNHILPPFNTSVGKIGSMICFDLRFPEIALSLRRQGAEILLYPSAFTVPTGKAHWLPLLRARAIECQCYVIAAAQVGKHNEKRESYGHSIVIDPWGEVVAELGGEGKGEPEVVLAEIDLERVRRVREQQPLKRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7H2</accession>
    <name>A0A9Q8L7H2_PASFU</name>
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        <recommendedName>
            <fullName evidence="9">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00833</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Mitochondrion inner membrane</location>
            <topology evidence="2 9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO12191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7H2"/>
    <dbReference type="GeneID" id="71980711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00833"/>
    <dbReference type="OMA" id="SNCRHDL"/>
    <dbReference type="OrthoDB" id="1916310at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10809" checksum="9A8E60926E774D69" modified="2023-09-13" version="1">MADSTKSVTPAVPTPNRPGRPMSEALLNEKWDHCLSTLLVRSTLGASLGVIFSVLVFKRRAWPVWAGLGFGAGRAWEECDSSFKRATAPSRDGLRVLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7N6</accession>
    <name>A0A9Q8L7N6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756662.1">
        <property type="nucleotide sequence ID" value="XM_047899514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7N6"/>
    <dbReference type="GeneID" id="71980244"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00366"/>
    <dbReference type="OMA" id="FTPGHNS"/>
    <dbReference type="OrthoDB" id="2384350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17716">
        <property type="entry name" value="BRCT_microcephalin_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
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            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="565"/>
        </location>
    </feature>
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        <location>
            <begin position="667"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="924"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
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        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
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        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
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            <end position="257"/>
        </location>
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        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
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        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
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        <location>
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            <end position="497"/>
        </location>
    </feature>
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        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
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            <begin position="542"/>
            <end position="555"/>
        </location>
    </feature>
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        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
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        <location>
            <begin position="1194"/>
            <end position="1203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1277" mass="138376" checksum="FE43CBFFFDD9F4EB" modified="2023-09-13" version="1">MVSTRGGARTSGGIATEQSLKKKPVRKTTTKPAPTAAKPKTTRAKKAEPVQETADIDDEQDELQLDTAAPTAKTARRTQAEKPKEDAAKPAKKAVSRAKKDEDTVKAPAAKPAAKVGRPKGSTKSVKEKPIESDNKKMELPPPAEPKGTRATRATASTAAKGRATPLSPKKITQVSRVPPKITTTKTATVKTTATKVTVNKAAPRGRPATRKRNISDENAEGLKVPAKKQALADDDQDKVVEEPDEQTTETVEAAEEEATRPTTPATPNGVVEPHAEEDAEGNTQEDDAASEPDSESDSSAPSGDELLGPKTPLKRCSPKEATRFSSARKSVPRMNASIKTPVRRFAVLGTQQGTPQTQKPYCKPSIPMSELRPMTVARARDRAMVFPQLQPLPKLKDNEDVEDWEQSDTPEGQDAHMKVDDDLALSRFPRLLTETDFEGNETSAELGDLQETISHMQDSELLQMEDEEEDSRSNDEPDDESGEDLEDSQDATEIDQDFNIAEPLENDPQHNTEVDPTVTAGEETGASRGDDRSLNEPERDLEADDTDVDMEDALPADPTPRPETLVWENVQDDITIPFGFEVDLSASRTLPPVEPTERLSLAGTLEQASSAKPESNEKTVAKQDIASSDVVAMGGAEEQSAARTSLDATVNLSDFLDVKSLAGPIRDHEPRVTADQAQDTESVSDEIEAADADGSPSPMKAHATPARDISELDTALEDIQDDQEFDIPRYARPTIASRRKSLPAIFYRTPTKDIERPMTAIGASMPRVEVPYGIYLFANAATPSKATPARPRTSMAHGLASEKKLRKASQTPVTGSPVPKTPGTSVPDTVQIRGAFTSPSRTPRPRLSHAGTPGTSVPESIRPTPRERFPGLPSRTAYDMESSLISATPLKSKAVQAERFPGLPPQDSYKSFVEDTEMVAMQVAEESPSMRTPKAAQSVTKERFPGLPPSNTYTESFEAANEEQAEEGAPSTPVAATGERYPGLPSKRSYAEHAMTAMPASRFRTPTQSPAKRPATAQKPASLRKIALKASTPRRTPLKAPTMTPGMEPMTPHPAAPLRGVVALVEVFTSDGGCATPAFTVLLQRLGAKTTKTFSERVTHLVFKEGSPTTLQRLRVHNKQVAETGMGKEIYCVNSRWVSDCDTGSMRMDETDEAYAVDVEDVPRAGKRRRKSMEPTALKNIGGNVVRDRHSTLGRSSLSRNSLKPDFDDSEMDVTPKASVDKENGGEDGSPATPAYLAAPDSLVQQTAPMNRVRKLDFTRKELEKSRRLTFFNGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Z3</accession>
    <name>A0A9Q8L7Z3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756841.1">
        <property type="nucleotide sequence ID" value="XM_047899473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Z3"/>
    <dbReference type="GeneID" id="71980203"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00325"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040109260" evidence="1">
        <location>
            <begin position="28"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="20555" checksum="9847627E4F103D31" modified="2023-09-13" version="1">MQLQHEMLFLITCLLLAATSLLPKGNAWSIDFYTGDKCGYSPEPFNRTTYHGPHQKKDVGNCLAAGDPRDGYDCDFWHDGGVRDDCTAPMQTGRAGLPASWFYPIGTICCVGFETLDECEWDECKYQPNLCIKGSWYNPKFEITEEWPFVTFYCYDGCPMADCEAFMEANDIDAGEDGMNVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9P5</accession>
    <name>A0A9Q8L9P5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757783.1">
        <property type="nucleotide sequence ID" value="XM_047901719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9P5"/>
    <dbReference type="GeneID" id="71982449"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02571"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="30305" checksum="966140EF22B33369" modified="2023-09-13" version="1">MADACATCASFFGRASDPASEKALLPGRYPECCGRSICSRCLNQNNRYETYCPYCQITTEPSLLPQGLRDPPAYSSLDDRTPPPVQPSPQDDELPAYSESQSNQAPREKKQPHEDVLHFLKPDDSLHSLSLAYGVPMHALRKANNVFSDHLIQGRKTVIIPGEYYSGGVSVSPQPLESEEEELKKNKTRRWMMACKVADVPVRLRYDVAVLYLQQSEWNLEAAIEAFREDEQWEMEHPLDAKGKAKGKIPAKNVGMRRFVGASTSVSSSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA85</accession>
    <name>A0A9Q8LA85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758142.1">
        <property type="nucleotide sequence ID" value="XM_047902301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA85"/>
    <dbReference type="GeneID" id="71983031"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03153"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="125" mass="14446" checksum="D8B38491BD62164F" modified="2023-09-13" version="1">MILMTMCLAVYKIPDQLKHHTQEQFFRLKSRHFTFKAISCAALDGIDVYLAWKMRAHHFGVALAATISSVLTVLAVTASARDLYLTRIDLDRRQKKHVKRLPVNHAQLPDITQVRRQDSWVAYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAB0</accession>
    <name>A0A9Q8LAB0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02947</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758128.1">
        <property type="nucleotide sequence ID" value="XM_047902095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAB0"/>
    <dbReference type="GeneID" id="71982825"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02947"/>
    <dbReference type="OMA" id="KYSWMTG"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="11">
        <location>
            <begin position="319"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="379"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="426"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="531"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="65554" checksum="D671F285FA1EE1AA" modified="2023-09-13" version="1">MSFSMSPPAQKPPPYPPYQQAASPQAQSPYAPPPAKRQRLSPDARSPQGAAPPYATTPNGMSGYAYGQPVHSPYSPSTSYAGSPQNSFNTPQPYQQPNLPWHQQPQPPQQRPAQSSPPAQNNDRGQMPPPPRPVKEEKEGVDEISDSLFGSGINLKDEENYLHSTWNNRHGAIDSFASNQTNSFGSSTMGSNSFNMLTQETSFGSQGQNGAFAGTMGLERSQEQIENEARRKREQAARLKAERDQFPLNNSFLLGNNVRNRMHFLAQEGGVRLNVQGVYVKNPEHETQTQVMVNGDGSQGVAAVDKAASKVEQGAPMEHIISLLSLAGGERLRSLVGDAYGLARARRYGDHGRVVPPEFADTAEGAGDKSQDTVVPESITGTQWDKTQASEPELNGEIQTNGDRSTPQAMQTVSFQGALNARLRELADRDRKAEKERQKKREARKKKAAESGEGAGTTPADSGAETPAAGAAPVEPAAPVKVSKKEQNKKAKEAQAQEAQSFQSSNITAMHALGNKKNRYSWMTGGAQGSTANRFAKSGGSGTATPKAQIDAKPAAAAKEKEAKGPTWGDWKEDSVDGHGIQLRDWVLVLERDGKEKKALQKAVNKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAH3</accession>
    <name>A0A9Q8LAH3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase dbaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758147.1">
        <property type="nucleotide sequence ID" value="XM_047902304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAH3"/>
    <dbReference type="GeneID" id="71983034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03156"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="30239" checksum="6F8174731FAEA523" modified="2023-09-13" version="1">MSPRESMSPLNDPASDSTTLHLPRPLCFHGGGANSKIFEVQCRCLEKALRDTFRLVYVEAPYISYPGPDVVQVYKHMSPFKGWLRWRHEDELRSAPAAVERINAAIKLAIDEDDKAGASGDFVGVLGFSQGAKLAASLLYTQQQLEEVMHERSGWPPFRFGILLAGRTPMVWLNADYDMPIGIVDAAAVSTAPTDHLPPMLDNQKLSVPTLHVHGIQDPGLPLHQKFLHNCCDPSSTTLLEWDGKHRIPFRHADIDRLVQGILNLARETCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB59</accession>
    <name>A0A9Q8LB59_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758563.1">
        <property type="nucleotide sequence ID" value="XM_047902924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB59"/>
    <dbReference type="GeneID" id="71983654"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03776"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="27255" checksum="0D16EE9289CBBB08" modified="2023-09-13" version="1">MEMSTQPPDGVEAKTIDGIRLQQLWLTYYPMPSWYMTPARVQQRDEFLQKARKIIQREDKRQQTSHQQRQVAENAIAEDGAVIAVHGHLPERPRPTTANPRSQKGPDRLASLVTHQRAVAQRQASSVHTPRAAPPQPQPSAARFPDYPPPQPPQAQPPASLDARREQFLQYQRRFRQAQQQQSQQYALAHAQARQQNQRPPAEVDPTTVRNRQRQYGLARASVFTPDEIIDLTQEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB77</accession>
    <name>A0A9Q8LB77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758593.1">
        <property type="nucleotide sequence ID" value="XM_047902336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB77"/>
    <dbReference type="GeneID" id="71983066"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03188"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="11800" checksum="BFE8A8D6D554105A" modified="2023-09-13" version="1">MANPNPNHIDLEDREALNIAFLKSAFMLMDDVLTILCTAIFYICLPLIILLLATMDRTGVTTERERHEARVREGLRRLEREMERRRGWTWREVWDAVWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBB8</accession>
    <name>A0A9Q8LBB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">mRNA decapping complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_02362</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758727.1">
        <property type="nucleotide sequence ID" value="XM_047901510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBB8"/>
    <dbReference type="GeneID" id="71982240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02362"/>
    <dbReference type="OMA" id="QQGHRAN"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1050:FF:000003">
        <property type="entry name" value="Decapping enzyme Dcp2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="104"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
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        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
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            <begin position="356"/>
            <end position="402"/>
        </location>
    </feature>
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        <location>
            <begin position="471"/>
            <end position="1019"/>
        </location>
    </feature>
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            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
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        </location>
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            <begin position="614"/>
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        </location>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1039" mass="113253" checksum="E29C5AA6786A71F3" modified="2023-09-13" version="1">MGDGAVDLTAVYQHMTLTDWLDDLTVRFLLNLPPAELSSVPRLCFQVEEAQWYYEDFIRPLNPSLPSLNLRAFLLTLFQHCPLLSGFQTEQHVRAYEEFLEYKTRVPVRGAILMNDNMDKILLVKGWKKGASWGFPRGKINKDEDDLDCAIREVYEETGFDATGLVEENRQKDGRVKSIDVTMKEQHMKLFVFRGVSMDTQFEPRTRKEISGIEWYNVKDLPGFRKQKGRVTGVGQGEAHSTKFYMVAPFLGQLKKWIGQQRRTEGSTPAQHGRSLSATNNALQAGITEDEGETEPEFATDNGLPTVDRSSEELKKLLSIGSPSVTHAPPAARQREPEHAAYSNAQTNNLLAMLKGSQPSMPISGPIPTTPSEQIDPSIPQQEPGTPQPHHPRKPSYPQMPHFAYSPQRLQEQQRNFSVPNQVFHQPAQHPQRQDTSHLPPHMQQMIFPQQQQQQRQGSMPNYFPHEAQRSTAFAQSAPQQQTQHSSGYGPSVGDPRNQNWANQPFDANLGPTRMQRPQLASPMHSFAGQRPQSSGKPIGSNHSIPEASKLPQPNLPAHTQLLLDAFKNGRKTQQSGSAASGSANQRHNSQQASALLDLFRKPSGQDSPKPAAEEVPAAPASPAVSDVTVKPRKTEKKTSIGEITTTLPARPKSKSPQPVMPSPGAGPQVNNPPKEPTEPSMLASIPSDVTLDRPKSRGNLYDPTKPKQFVRASPQTGRQESPKASPKAKTKQNAQSPRQSSHPTPPTQPTQPTPQFSILQRPSTSRSPVPQSPLRNESAGTNLQPQVLRRPGDGLASELAAQETPSPPPGEVKKSHLLSLFNKSPSASAPGPVARPPAQVNVTSPVQTHTGSTGKDALLGLFNGKTTSSVPPVKTPEPPSTQPQTTPTSKDALLGLFNGKTTPSVPPAKIPQPPPTPQLQPDTRPSQSQQGHRANGGGQQQLLLSMFSRPGSASSAQSPGTPVSPFTLGTPLTKEPPAKLNVPEPRSRLESVHSVTSNGTTSGQQTPGSATPTETNKGFLLSYLNEVVEKEGHRGAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO14352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="18413" checksum="B4B606BE346E1FAF" modified="2023-09-13" version="1">MDKVPMEPWSQEVVVIVRQFQDKKARLKGKSPVQVKEGTGEVDDEMSLEELYRELRQLALLSVGMKAATPGFHGSLSLTSPGHATVILLNEEDWKKHRDLLRPRGARLVIDFDVESLEVKETKPSSWLEKAKGKAMAKVAKVDEAIRKEKDAQQEQFKNSWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBX2</accession>
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            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
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    <organism evidence="1 2">
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                <person name="Samaras A."/>
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            <dbReference type="PubMed" id="35471194"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="19937" checksum="E320BD9A53CA6CD0" modified="2023-09-13" version="1">MRVTTVLSALRSQCIAFRSVRSFATTRPAQAKNRIYPSRVRNEDELQTLLLASASTRIPLLTLWMTTWSRDCDEVSPIIRGLLEKDGIGEDKGSVGFVEVEMDSPDLGGVTGIAQRYMINKTPTLMAFDRQEPQIETKVSDLGQLKDKQFLTQWIEKEAARHGEGGAGGSLSGLFSLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBY1</accession>
    <name>A0A9Q8LBY1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03805</name>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758911.1">
        <property type="nucleotide sequence ID" value="XM_047902953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBY1"/>
    <dbReference type="GeneID" id="71983683"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03805"/>
    <dbReference type="OMA" id="HADHHEA"/>
    <dbReference type="OrthoDB" id="4590707at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="299" mass="32087" checksum="E076D200C1FCE653" modified="2023-09-13" version="1">MPMIRVNALRSLRFTGARATARASAGRTQVVAKRFSSSGGSHGGHGEPSSDLPWLLSALAITPPSVWYLWPDKSHAEHGDHGHHEEHEEHGEEEEKPSEEDQSSEDEAEQVDSAPAEQADKPEKTEEKAGQSSEKPEEKSEGGEEKSEGGDDKQEGSEDSGKSSEGDSQEKPKSGEVEGVNFKGKMKPDSDGHKDTRKTEPNPESRGTQKRRIDSGLGKNLGEGDSSSDQSTAKPESSDVGDITNKQKGFSTIDTRHSIQIDQRDDKSKKGTGEPETAKAKGTVDPNAPVRGGPGQNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCG2</accession>
    <name>A0A9Q8LCG2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759030.1">
        <property type="nucleotide sequence ID" value="XM_047907328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCG2"/>
    <dbReference type="GeneID" id="71988058"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08180"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
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        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
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        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="496"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="824"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1113" mass="124822" checksum="0252CD013064B434" modified="2023-09-13" version="1">MARTIDQILAFRHGLTDAVTSFEVTQRTKLVTLHRHDLWTSEGRELRNLTSVARPSQRCRLVIDGCEFPPRSQHPGDSDYCESLATFNRLPEADFCTPLTAPTVYIALEWPNLRDQPSVIIQCHFNALANDIPGIDDFVVERKTNANGNAVDEAVFIAGGVAVEGFNQPELRHSSTLKQLRRLLEDDTRLKHMRLQFGQLLSVHSPFRALLPYVAQGSIYRLSSLTSGQWSQLLPPKPERDLSELIYGPNPLPMVSYECHDTYTTVNEAIVELYESARMAHLEQEVALEEWASVPHNGTLYRIGGAMVMAVRFAPTRPLGGPAGIVKIDLPERLRVSMTWDDPMTGEALCASGSRTVVPLRLPIGYDALFIISNKRNIEEHERLREACLGRNDTDRRFAAQVKFVATIPRGTLYNQLMTAMNLEQAHSWHEIILNQRHDQLTRVDLATSRLGPAIITDLNTSQPDSTSVMPDLAEEAVTVGVEQALEWMLNWRNWNPEQLQALHSIRQAVGRIVLITGPAGTGKTLILQAICVFFYLMDMHVLVLAPANSNCADFMRKLVQLFPKDTTVCGKEVLATRVFPPSADFSPEKEAKAHHGTSRPASNETDRGAASARLDVPASSVPEPSPATDSGFADVFDLEMIRSELHSSSDKYSQFKDFGLAQQVLNAAHKGEKTLIEQLGREQPVDVWQVLRQCLDDAQAGTFDWNNKLAVQKYQQSYDACKAHFMSKQRLVVTTTGNVRCDDIVNNFASNKHGVECKGMIVILDEACKDREIDSLSAILHPDWRAKITGMIMLGDERQLEPTNTCAKGRVQFNPFSERLNIPLLSRLKREGFPCVELVEQHRMSHHISSWPSKNFYGSGMRDGEGTKGTLADKQPGLFACLKSILIGAGSTSFGAPSSEAKEDKSIRTHYLELRGTRDNSKKSAFVQEHVHVFFDRIYWKLRAYYGEKMEEQCMIIVAYKGAMDIWHEAMAHLQRKYNIPTAQMPRILTIDSSQGAEASVCMIDCSVQEYSSESRRKDIGFCDDDKRMNVAMTRAQEVRWFLGGSCSVSQRAPGQADTPAYVRFKEEAANNEVTVVDNCLLPRDDLGWLDSLRKQEIQLGLRFSDEVKVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCN2</accession>
    <name>A0A9Q8LCN2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ASST-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759447.1">
        <property type="nucleotide sequence ID" value="XM_047907699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCN2"/>
    <dbReference type="GeneID" id="71988429"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08551"/>
    <dbReference type="OMA" id="MHEFNIM"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF8">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040228667" description="ASST-domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="698" mass="77742" checksum="42EF61CC89AAD343" modified="2023-09-13" version="1">MTRRLAAFAILSTALSHVRAAFDIGYGDDSDLTNFVTRPEIKVPVFEVQVYKPEQVTPGYWFVAAYAFISQQSHAGNYYQPCQSGPTIYDGEGNLVWSGACAKKNQNTCDFRAWNFNGTNYLSAIFTPYNGNNDTQGHGVFMDNSYNELYEVHNPVTIDNFNMHELNIVDGGTRAINILFNPVKLELKELNQPGAGWVADIGFRETDLTTGETTFEWWAAQGGHVSLAESKRPTENLGRQYPASWNWFHGNAVEKNEEGDYLLSARYLDTIFKISGKTGKILWRLGGYNTSFDQDFVFSRQHDSRWLHSGKDKEIVSFLNNAADDQSTDESNGMVSRTSSAMIVELDHTKSPPTARILRNILRPDGLLSRLRGNHQVQSNGNSFVCWSENAYISEHAPDGELLMEAAWRSRRFVTYRGYKFNFTAVPKEAIAAKGFTYGTSAAKATTVVYVSWNGATEVETWRFKAPPGPHGSHKAETLGTKNKTGFETQFQVDGFHHTVFVEGIAANGSVLGTSGRIIITPPVEWENVPQDVLVDTAEKDDPKFKSRFGTGKTRHHFQLNHSVHDAATTNSDSDADTDDNIQDDLNETQHTKHEGAMTPSGDIKIKGTQGTQGTKATTEPKEPTITTLKSKAQEFLAHPTGSQLMIWLLGANGLLVGTVLAFRRPGYYRRSSSKLGRRIRRAWSPSSRDEKRVGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDH5</accession>
    <name>A0A9Q8LDH5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759585.1">
        <property type="nucleotide sequence ID" value="XM_047907201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDH5"/>
    <dbReference type="GeneID" id="71987931"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08053"/>
    <dbReference type="OMA" id="EPLAHIC"/>
    <dbReference type="OrthoDB" id="5317787at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="487" mass="54978" checksum="2D953A4A7EF19BDF" modified="2023-09-13" version="1">MALHHRPELDDIRSAYSGSMAHHSDRSFQSDRESHRSYQRSHSSSDKSYSTQPTVYSATSARRPPRVHYNTCDDYSAAPPTSRYFPEQAPPESPRASVETYASTVPSEEDLPEETPEYEVPQYTARPYEPAAIAATPSDFSELFPSHRRMAIRHDDATLDGNMNLRVDTEVTMHGGRRCDMTLFHLRMHDLRDREFSLRRYCRDSGREVCHSARKQQKPASPKRPSFQRSLSNALSSMRSRSEQRSPTMASLKRNDSGYGSVHSSLDMDRDDRYLQASQSPAQSQQAVDPHTVKLEFSNYAQLDVRRAGTKANKRYEFEYWGTPYAWRRVVKKDNPLNQCSYHLIKSGSEEVLAYIIPSPPTPGQAEEEQSKGGWIPPCSMWIADDSIVRGQKDVADVVIATGLMALVDDSIKARFHARDSKQLLIPKLQMGIEYVGPKRLINEMFKREGGGQRSRQPSHSSRPSSSAGPSSASGTRAAVRQSSNNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEQ0</accession>
    <name>A0A9Q8LEQ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO15323.1"/>
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    </evidence>
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        <source>
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    </evidence>
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            <begin position="162"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="17601" checksum="67BA6C8329693424" modified="2023-09-13" version="1">MKLSSAVMLAIAGLAAAAPVEISENVKNIFERQQQTCVRVGQSCQQKPNGCCNPQQNFCNQTFVCQSRSGGGGGGGGGTPPGGGGGGGTPPGGGGGGGGGGGGGGGGGGYSGYSGYSGGSGGSGYSGYSGGSGGSGYSGGGGSYGGGSYGGGGYGGYYRKADAAAAEPPKEDPTTQITAPPLETVAEAAV</sequence>
</entry>
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                <person name="Samaras A."/>
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    </dbReference>
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        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
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        <location>
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        <location>
            <begin position="197"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="210"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="597"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="4">
        <location>
            <begin position="740"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="973" mass="103551" checksum="476DD3FD8EFB49F8" modified="2023-09-13" version="1">MTSRAVKSIRIGVGVGGTNTDAVAIDPSQQFESSRGVLAHHKTPTTPDVSAGIEAAVRTVIAKSDLPSDSIASVTIGTTHFINAVIEQDARRLRRVAVLRVSTSFLREVPPFSELPPGLTSIIKGYVGYVDGGLHIDGSEESPIREEQVVARCAEIKKLGLNAIVVVAAFSPIDDHFRQEDRVRHIVVREIPGAHVIVSHEVANIGLIERENASILNAAILRYAKRSVKRFRRAMKALKLTCPLFLTQTDGTLLDSAAAAKIPIRTFSSGPTNSMRGAAYLTGHETEKSSAIVVDIGGTTSDVGVLLPSGLPGQASAYATVAGVRVNYSMPSLHSIGLGGGSIVREAEGEVDVGPDSVGHCLTRDALVFGGTVTTASDIAVAAGKAEMGDRAALKSLNPRLVEQAQDRIKALLEGAVDMIKTSPEPLPVLVVGGGAVLAPSSLKGASQLRLPPYHDVANAVGAAISKVGGIVDIIQDVSDQTQQQAIEKAKTMAIQRAVDAGAIRESVIIAEVEMYPVSYIANQLRTIVKAVGELDINMQHEQLNEGEGDDADQETEAAKDFAVKVIDEPPVDPCTYKPTIVKHRTTGILEWHITETDINYLADGCYVLGCAGGGSPAASRIQLRDMLRAGHKMRVIDASSLKDNANIYWGGHMGSPATSNERLQSLETIHAFRALMEYLHEDSFDAVMGLEIGGANGLEPFLWRLITILRPPLHAPGELAPCAIDSGDGKTILMTKASNDEIVDRALRASCAEMGSRVGMAAKPTTTQKVRDFGVLNTVSLAWRVGRCIAIAEATNTLSTVAEVIVHEVGGEKSAKILFRGKIVGVERRLFKGHSYGSITIAGLSTDEEEDAGSYIKRMPAVATTGTITIPFENKNIYVEHTAEDGEKTMIASVPDLICVLDTASGRSLGVLPEFKYGYRVTVLGITCSPRWSDTKAGLKIGGPGAFGYDIPYKPLGGYVEPRSVIEEFAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH86</accession>
    <name>A0A9Q8LH86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761773.1">
        <property type="nucleotide sequence ID" value="XM_047905382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH86"/>
    <dbReference type="GeneID" id="71986112"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06234"/>
    <dbReference type="OMA" id="KSKWINE"/>
    <dbReference type="OrthoDB" id="3906254at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052924">
        <property type="entry name" value="OsmC/Ohr_hydroprdx_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368:SF1">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="19431" checksum="D2EB7FE1D80173B2" modified="2023-09-13" version="1">MAIMNRALRGLARQPVSRSIGSIRPFSSTFALHDTIPFHVDGQGTGVAQTVGVKDTIRTINTDAYPAFGGKNEYPSPLHFNLTALSSCTQVTGSIVAKDHGINLKDWKVSVTGQLDPAVLVGGAEGNANWTSINLDVEVATDADGAKFDKWTSEVERRCPVTQLFKRSGAEWTSKWVNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHX7</accession>
    <name>A0A9Q8LHX7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761309.1">
        <property type="nucleotide sequence ID" value="XM_047903055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHX7"/>
    <dbReference type="GeneID" id="71983785"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03907"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="49734" checksum="0D6D80B974C3164E" modified="2023-09-13" version="1">MTQDFIIAPFAPTNRSRAYLTRNGQNTSSQQKRKPTARDAAKLARQKILATSASSRINIGRVGKAKIKAKRAKARKPMRKAGPGEDEEQDSSEDATMNDDGAHEKSAEPAANSTYRAERELSAPEKVFGIFELCEIIVSNLPTHDLFRTRGVNQTVKAAINDSKVCKEKLFLTPTSAPPVTWLWTVGEDVYHSVPYAPSSAFPGDWIGDSDQASPYDVQQPRHLNSMVLRRGQVEPVRHPFQHWPRFSLKIPSFDTADTAVFDEMFLTQSPVQSATFSYSTIPRIRATDNTRPKVTLDIPGGIRLKHIREAVEAFGHANNTLYDTRLAFHERDATFSSEATFEEMEVHGELICSVIHAHREREHAVRGGEQDKETFGLGKMVLEDTEPAEVVQDPMDMTDMRESLPEVAGWSSSDPAYAFRHARSRAYTIHGSGIKEPITSERQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK2</accession>
    <name>A0A9Q8LIK2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762505.1">
        <property type="nucleotide sequence ID" value="XM_047905767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK2"/>
    <dbReference type="GeneID" id="71986497"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06619"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="24877" checksum="01EC3F57703C86D1" modified="2023-09-13" version="1">MQYKEAEYLAGFEVRGTKKAASQQQRHIVSLNFHSLSNHPLCKQHHSLILASFFILHCLRHSIHCENPDIFAVLIQFFYRFTLAEFNDPILAVLIYQVADKYDVPGLRKLAANRFEKSCDPKNNFEAFGTALKEIDERTAPNDKTLWEIVVPLVKQNMGFLLAQKEFKSTIKEINALYFRLLEEWSLDDSGENAAIDPALLADGGTSFVSIGWGGGRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIP2</accession>
    <name>A0A9Q8LIP2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional activator protein acu-15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06496</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762466.1">
        <property type="nucleotide sequence ID" value="XM_047905644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIP2"/>
    <dbReference type="GeneID" id="71986374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06496"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="742" mass="84101" checksum="F6013A15B50693C2" modified="2023-09-13" version="1">MEHKRRRVTRACDRCRILKTKCDGQQPICSRCSAYGYACKWNHGGRRGITHPDVSLSLGATPSSVAPSEPDMTSLQEAVRAYDELLSTLRTNVPEGERAKVDLAQARIRTHLPSELWDQLPSPKASEETETQDNYGTTESRPRSAKYLGWSSDVEFVNSIQELLRDSRLADQPSVCESYEKTDSTSQRNSQQYPLRLPTRKIADHWLETFFATIHVAHPVVCQQRFRLQYVKFCESLSTSDVSRTWSATFLSILALGSYYDTFSNGESWDSCTHEGYFMYSQAMTKSHGSEHSRDYVCLLIVQCLYLLATVQTDKCWTTLGTAIRIAQSLGLHVEDEATRRESHHFQIEHEMRRRTWHSLYVLDRLLALQLGRPLAINHADTAVKPPSQIDDMEFDLAGDRIPDPTFSWRPQFGDYFRAVVRFSHIVGSVVRDLYRPNSQQNLDFELVEDIDKRLLQWRSELPQSLRFDMEHSTDTTVTLRRQRNILSIKFHHLRALLHRVHLCLPWLLSEDSSIMSISDAERQQIVSSEAICVSEARAIARTMENVNNEQDLVHDFPFWQMISCLICGASILLVASKFQVPPSPVDTVTALEADAAVCIRIFDALSAHSDAARLAAKMMRALQLYKRSTVPLPWRPRNIRSSVTQETAFPTPSYASTPFTTAATDYGSANWVTNDSWPSECSDSLSWSSQFVTLDDFFDPGLYLGADMASAVGVPPMQTVPTAPLNNNMQVMQPGALPQWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIW3</accession>
    <name>A0A9Q8LIW3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762688.1">
        <property type="nucleotide sequence ID" value="XM_047905394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIW3"/>
    <dbReference type="GeneID" id="71986124"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06246"/>
    <dbReference type="OMA" id="EIQNMHG"/>
    <dbReference type="OrthoDB" id="203381at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052275">
        <property type="entry name" value="Mt_Fe-S_assembly_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188:SF1">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13281" checksum="8C1F3F90D6D1E601" modified="2023-09-13" version="1">MAARTLLPRLFRAPLRQPITPSSLIARSSLRHYSDSSSVQAPDYLSEGERKVFALIKEGLQPTKLEVQDISGGCGSMYGIDIVSEKFAGLPVIKQHRLVNQVLGEEIKKWHGVQLKTKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJE2</accession>
    <name>A0A9Q8LJE2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">P-type Na(+) transporter</fullName>
            <ecNumber evidence="20">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">CLAFUR5_07559</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="26" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="20"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762858.1">
        <property type="nucleotide sequence ID" value="XM_047906707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJE2"/>
    <dbReference type="GeneID" id="71987437"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07559"/>
    <dbReference type="OMA" id="FGIDDYI"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000160">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0915">Sodium</keyword>
    <keyword evidence="18" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 24" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="817"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="850"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="900"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="942"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="994"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="1026"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="25">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="UJO18492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1075" mass="115936" checksum="DB6F611921F42200" modified="2023-09-13" version="1">MAKPLASSNHVDVETQHSAAQHGGGLPATDDGGNVDDPPPIPNGVASAASSTDSVLLNDKSKGGARTRNTTTTNSSFITIEETNSDNIHAHAHTLSASSVANILATDAQNGLTANEVTHRRERYGSNKLESSGGIVWWRILLRQVSNSLTLVLVIAMALSFGTQDWIEGGVITAVIFLNIVVGFFQDYRAEQTIASLLAMAAPECKVIRDNGNLTNIKAEDLVPGDLVQLVTGDIVAADLRLVNSVNLASDEALLTGESKPSVKDADYISDKIDAPVGDRTNIAYSSTTLTRGRGAGIVIASGMNTEIGKIAVLLRDKPPSKEGPWLVRCGNRVLRGIKNALGLVGTPLQVKLSWFALFLFALAILLAIIVFSVNLWDIDDETLIYGICVAVAVIPESLIAVLTITMAVGSKAMARGNVIVRRMGALEAIGGVTNICSDKTGTLTQGKMLARKAMLPGGRFISVENETHPLDPTTGELKLDGKPLALEQIWPELELHRFFQIIALCNVSTVKAPHDEEAQWTATGEPTEIALSVMALRAGCGKQDTIHREGLRLLTEHSFDSAVKRMSAVYASDPNGELTCFTKGATEFLLPLMRVNEATSKAILAQADAMASEGLRVLCLAYRTLNPDEDSKIMDREHVEQDLMFAGLVGIYDPPRLESAGAIKQCQRAGITVHMLTGDHLKTATTIAREIGILAPHVTGSSSADAVMTASVFDKMSDQDLDNMASLPLVLARCSPTTKLRMLDALHRRGKYCVMTGDGVNDSPALKGADVGVAMGLNGSDVSKQAADLVLTDDNFASIVSAIREGRRLFDNIRKFLLHLLISNIAQVILLLIGLAFKDNNDVSVFPLSPLEILFANLVSSSFLAIGLGLEEASADVMTRPPHSLKAGVFTKELIIDKFIYGTCMGCLCLASFCIVAFGVGDGNLGDDCNHNHNDTCDLPYRARGTAYAILTVLLSVMAWEAKHLDLSLFNMYPNEDSRKGLSFFSTVTKNRFLFWAVMAGLVTPFPVIYIPVVNRIVFRHLPLTWEWGLVAGSIVVFISLVESWKAIKRRMKAKKARKNPIEVNNFDNDKSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJT8</accession>
    <name>A0A9Q8LJT8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762374.1">
        <property type="nucleotide sequence ID" value="XM_047905543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJT8"/>
    <dbReference type="GeneID" id="71986273"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06395"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27587" checksum="CED92E4D62BF6080" modified="2023-09-13" version="1">MDASNEALTMALDPWYYDNELDFALTLCDFNAPCADPEITLPVGYDSLPQRMNNTIGPWQLERQYGLICGPFDDSWQSSQASDLSTFSSPTAEASSSTLFTPAIHHDLLRQDPANLRQRRPRRSARTSTPTTPHEYLAGASTNYAQETDLSPQPGVPHTVIERRYRVKLGNHFQALQSSIPTLRDPQVPAPIADELLSKDTLTKGLLSTHKRNKATVCLKAVEYIQHLETKVRAYEKLHRHDAQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2I6</accession>
    <name>A0A9Q8P2I6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Steroid-binding protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755361.1">
        <property type="nucleotide sequence ID" value="XM_047899957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2I6"/>
    <dbReference type="GeneID" id="71980687"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00809"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF115">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="2">
        <location>
            <begin position="54"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="164" mass="18868" checksum="468811A009245E8F" modified="2023-09-13" version="1">MIDQSHHRICRHVIPERHLQDSISPHFQHRYTKMAGKFEPKHKVDLDPPKDDIISVDHLAKCDGKHEGFPTYVAIKGTIFDVTGNKAYGPEGSYKVFAGRDASRALAQSSLKDEECRPDWYDLSPEHKKVLNDWYTFFSKRYNIKGKVEGAQNTGEDQPEEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2R9</accession>
    <name>A0A9Q8P2R9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase/reductase dpchG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755318.1">
        <property type="nucleotide sequence ID" value="XM_047900966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2R9"/>
    <dbReference type="GeneID" id="71981696"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01818"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO10952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="26790" checksum="CEFE6B5F44A9985E" modified="2023-09-13" version="1">MAHQGMTVLVTGGAGGLGRAIAENFVDLGANVVVCDINKDLLADFNDKVVAASADRVLAINCNITSEDALDDLFSQAESKFGPFDYVVNSAGAADKFDAAGSLERNDWDRIISLNLTAPTFITKRAVNGFLKADKKGSIVNIASVASFKGFANGAAYTASKHGLIGLTKNTAAFYRLKGIRCNAICAGAMQTNIGSNLANGFNMDGMMLMKQTFGEWEGGFADIKKMAKLVAFLCSDDAEMVNGAMVNADGGITAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2W4</accession>
    <name>A0A9Q8P2W4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inclusion body clearance protein IML2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inclusion body clearance protein iml2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as a chaperone in inclusion clearing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with lipid droplet proteins.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755555.1">
        <property type="nucleotide sequence ID" value="XM_047899526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2W4"/>
    <dbReference type="GeneID" id="71980256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00378"/>
    <dbReference type="OrthoDB" id="2154985at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="706" mass="78762" checksum="A2B1514CF9598269" modified="2023-09-13" version="1">MAMKRVGGWLNPSKGSLASSKSRTAIDEPHALQEAMRSASLILNDETERAESELAQGTSPFHKLGRATTIFLRATLGFEKEIMEQASSRLADAEESASEHQRRAIRDPSTAHQSKIYPVGAEYALCHAETQLMTAVVGVLNESLTESLRGFYKLRKAFSTLQELVEAENRYLEKHISSSQSSLASSTATSSGVMTPAEDGSDDEDLDFQDAQEGVNGHAQPMPTDYQGHLNLPKVADLKLEDKSKVIPSIEQAPSRAPTTESSDPTRLAKTAHDELDFTSVSRDEIDIFIHSGSALCFGLLQLLLSMVPPAFSKLLSIFSFRGDRENGLRLLWKATAFKDNINGGMAGLITLGFHNAAIALCDIHSREAYPEARIRALLSDMRSLYPKSFMWILEEARMLNADRKLESAVELLTTGSGVSPLKQVEALRVFETSLSLMFLHRYQECADSWIKCVDLNNWSHGLYYYIAGACHVELYRITRDADPTAAAGHKEKAKKLFHTAHSQSGKKRFMARQLPLDVFIQRKFAKWAAKAKAQGRDEVEVIGVSPLEEMIYFWSGFPRMSPEHLQLSWERLSWSDDSKLNPDWKDEPVDERALLSMLKATTLRCLGRLPEAQTLLAEEVFCHDLAQIKACPHADNWSLPVGHYEKGVCHWQEAGGQDGDRAKLQECSNELTLVERWESFELDARIGLKLTTARETLRRIGIGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P306</accession>
    <name>A0A9Q8P306_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pisatin demethylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755675.1">
        <property type="nucleotide sequence ID" value="XM_047899295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P306"/>
    <dbReference type="GeneID" id="71980025"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00147"/>
    <dbReference type="OMA" id="AYIMRYV"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF188">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="59258" checksum="FEE23840D9997D12" modified="2023-09-13" version="1">MHTHTIILAAAVAIVARLTYILYSLLTSSLRSIPGPFLARFTKLWYFNSIYKGQAHWDNISLHRKYAKDGAFYAPIVRLGPKMYSIAQPDQAVYGIGSKMPKSSWYEGWKHPSPDRWTMFPDRDIKRHAETRRKFQSMYSLTSLLHYEPFVDSVGAIFKLRLSEMATKGARVDMHHWLQCYAFDVIGNITYGHRFGFLDEGKDIDRCMTSLESSMMYSTLVGIYAWAHPYLYYFLEKYFPNSGAAGRSYIMSFVRKEIANREVVRKGLEAKGERPGPDGDAPRDFLDLAMDAEQDQEKGMTKYNVFMMGLSNIVAGSDTTAVSLSSVLWHLTTNPSVLAELRQELDMAITEGRMSRDRITLKESQDLPFLQACIKEALRMCAATGLPLWRVVPEGGIEMLGQYFPAGTEVGINSWVAHYDEDIWGPDAKQYRPQRWIEAQEDKERLREMESHYLPFGLGSRTCIGRHISFLEICKVIPMVVSNFDFDLTKSTQELKTENYWFVRPTDFEVQVRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P317</accession>
    <name>A0A9Q8P317_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribophorin II C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02037</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755662.1">
        <property type="nucleotide sequence ID" value="XM_047901185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P317"/>
    <dbReference type="GeneID" id="71981915"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02037"/>
    <dbReference type="OrthoDB" id="432292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044328308" description="Ribophorin II C-terminal domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="9">
        <location>
            <begin position="179"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="30799" checksum="B579443F12BDDB1D" modified="2023-09-13" version="1">MRLLQSLGVIAIALSSVATAASLWTFDDATLQIATKGAEPVKQKLNADSPVSSSSPVTLPAASTLKILLTAKEGKTGKRPHQAFLTLQDPDTGLEESLAFSVKDNGKATVAVAPKDLPFQLLTRSKPLKASITLASFGSSTPYNSQAFNLKIEKDTSNPPVIPSPPERYTSKPEIHHVFREDPRQPPTIISLFFTLAILVTLPAWIGGVMYLGGNFDHVGKAFGANPVAHGLFFGSIVAMEGVFFLYYSSWNLFQTLPVAAVVGMVAYVSGSRALTEVQERRLAGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3S9</accession>
    <name>A0A9Q8P3S9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ran-specific GTPase-activating protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756711.1">
        <property type="nucleotide sequence ID" value="XM_047900940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3S9"/>
    <dbReference type="GeneID" id="71981670"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01792"/>
    <dbReference type="OMA" id="WDPYNES"/>
    <dbReference type="OrthoDB" id="512915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008812">
        <property type="entry name" value="Ran_GTP-bd-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010:SF2">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05508">
        <property type="entry name" value="Ran-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="716" mass="78866" checksum="EDE6F6D68EAA43C5" modified="2023-09-13" version="1">MDLILQRMTQQAMQYALRSGISITTGYAIKECARLYKQAPKSRDREELMLLQQRLESKIRVISPSIDMIELIAARGNTSLESAVSLTKDIRYEIQKLGKRLQDAANDEELLRHRSNKAKSREDTSQELKGCIDHIKLLLARIEDAVPLINLAITTSGVNLSTKLSGTISPSRLLQASTFLTSADSQYSTNVTMRQQVGSTYVLTLYMLFAGHATRPVTEHGVRETTWKEVIHKARVKLWRIPLEQLYTLPGEHTQADGHDAANTIPGDAKASEFAYQLSIVEDLDDDRHHNPEDEGHSPGPVDDVLEAGIRDVIPIHEISKIFYADTGKILNIGGDGDAYSPVLLLKRDVHAEPPRRMLRRSQSRVSINEGVANTSISDDDDQDDQTEIDAQFERESAPPTPLNDSESAPQETHAWRLPADLDPEWMALEVYTEDDESESDIDTSPEPERPGLSRAESLEPGLSDALANLNMNSDGSSSDHHLAPNKSQVLQLSPGRRAGPALKSSLSLLEMLMKLAALQQFRQESHLAIEDELLNFFLEDSATAGAGADKQYRQQLRQTAARRVGFDPYDESPVKRRGEDYIRNAGEAASPRGSPGSGLLYRDGFDGLPVPQLDFAARPSIERLGSRLPSSPPQRPPYQTPSRTSTPDTSEGHQKTVRAKYAGDTPSPPSPPAARASAESTTTTANGAKTRAATLRSKTDSRPRSPLRVVADGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4B3</accession>
    <name>A0A9Q8P4B3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="9">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757159.1">
        <property type="nucleotide sequence ID" value="XM_047899158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4B3"/>
    <dbReference type="GeneID" id="71979888"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00010"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000105">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="10">
        <location>
            <begin position="47"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="11">
        <location>
            <begin position="212"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="51"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="33590" checksum="4D5DCFD230F2A2A3" modified="2023-09-13" version="1">MLFLHNSTVRQLHGSRLRIVCTVPKSLSITNTVSSVANMASELSSKTIAFIGGGNMGAAIISGLAAKGIDKKNIIVAEPWDVNRKKMDDLGVRTTTNNVEASSGADIIILAIKPQVAKTVCQELAASAFFGKSLPLVISIAAGVTAASLKDWCKTKEGKSPAIVRVMPNTPALLGEGASGLYASDEVSKEQKDQASALLGSVSQASEWVDKEELLDVVTGLSGSGPAYFFAMVEHLVASATKLGLSEEVATRLATQTCLGAGKMLVQSSEPPSQLRKNVTSPNGTTQAALESFEASGFAAIVDKAVKAATDRGEELGRTLGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P551</accession>
    <name>A0A9Q8P551_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758136.1">
        <property type="nucleotide sequence ID" value="XM_047902377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P551"/>
    <dbReference type="GeneID" id="71983107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03229"/>
    <dbReference type="OrthoDB" id="27198at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DCUN1" evidence="3">
        <location>
            <begin position="56"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="30173" checksum="C93E8CD794182765" modified="2023-09-13" version="1">MPPAYTSSQKSAIAEFSNVTQADKSTAAKLLKQHSWNVGAAVNTFFNNPSAGGANSLRSSLSKTFDQYRDNPKDSPDEITIDGTGKLLEDAGIAVDGVDFFIFSELVASPSMGTLAREGFVDGLSDVGADTPAKIRNIVLQRRSALNSDPELLKNVYNHAFQLGLQDRQKALPVEMAQEFWKILFTAPAYQWRTNSSPWLDWWFEFYTEKVNKAVNKDLWKQTLSFAKETMRDESLSFWTDESSWPSVIDEFVEWVKTQKKTGDAMEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5B8</accession>
    <name>A0A9Q8P5B8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757958.1">
        <property type="nucleotide sequence ID" value="XM_047903024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5B8"/>
    <dbReference type="GeneID" id="71983754"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03876"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11485" checksum="713EDF998A733A57" modified="2023-09-13" version="1">MTQEVHKLRGGLGAEKARSKASHDQVFQLRKWMSDRDRTITKSLADKEELRKQAAGRDRKITSLTNPGSSQPASGNAPVSRYKFPLPPPPAALMPRSYRKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Z4</accession>
    <name>A0A9Q8P5Z4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02481</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
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    </dbReference>
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        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
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            <begin position="164"/>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="27968" checksum="EAD738841A093696" modified="2023-09-13" version="1">MADHESFPEVQGGGSLILAWQVRNKRVLVIGGGEVAAGRILNLLNADALVTLISPRDGLNPEVAHRIERGQVTYIDRVFEPSDLDDPEITMVLTAIDDPEASSQIWKLCKQKRIAANIADVPPECDFYFGSVHRDGPLQIMVSTNGNGPKMANIVRRRIAASLPPNIGDAIKKVGRLRRKLRDVAPEIEQGPKRMGWMSKVCVQWTLEDLCEMTEEDMEGLLEFYGPDQVPSLVEVRGPWEFDGSFGWSCVC</sequence>
</entry>
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        </submittedName>
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    </gene>
    <organism evidence="6 7">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UBL_ZFAND1-like"/>
    </dbReference>
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        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
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        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="34236" checksum="F67EC55EE00BF71E" modified="2023-09-13" version="1">MSNSRPSEPPTDETFSKLAVGDVEAIGAHCQMTFCRQLDFLPFKCESCQGKFCLDHRTETAHQCPKAGEWARRRADANRGAALRGYTPSPKPNILTHEQQCSERSCKTLIDTPLVTAVQCDKCNYRYCLKHRLTHEHNCASITPKGARPSNGPTQKEKGLAALEKLRAWGASKTASLPQTKAKQSAAASIAATATLKKTAKGEDKIPQDKRIYLHVEASSDTITAKIPKGNFFYSSEYSIGRVLDLAAKSLQVQNMNNRSESEEDKLRVFHVEGGRLLEFGEKLGQSVQTGNTIVLLRGVGAGMAKTPEQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6W3</accession>
    <name>A0A9Q8P6W3_PASFU</name>
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        <name evidence="1" type="ORF">CLAFUR5_08200</name>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO15448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="13588" checksum="F81243512BFFAB5E" modified="2023-09-13" version="1">MIVTATLVIPSVLSLDIYRETDSRTVLEEGFRIEHFEFFDLITSTLFTYELFLRIYDPSDSISLYNLIELYASVTRYIKDISPLTKPVRLLKKIVGYAISKAKLFNGRRYVLINTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7J3</accession>
    <name>A0A9Q8P7J3_PASFU</name>
    <protein>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="71985039"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05161"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="142" mass="15984" checksum="0ED75DEEC7899120" modified="2023-09-13" version="1">MSNFHAPHNFFQMNQSVDLSFAMKTAGLPNSASTSGPRCIAMLAMRLALIAIFTSLFRNPAHGKELFDIWLKRYRNHECAGRSVSGPNVLRGNGKCRNWEDNTPFNNLTYAWAAHRAFYEKPEDHGSCVIRVWENDGCTGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P827</accession>
    <name>A0A9Q8P827_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760883.1">
        <property type="nucleotide sequence ID" value="XM_047904182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P827"/>
    <dbReference type="GeneID" id="71984912"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05034"/>
    <dbReference type="OMA" id="LMEMLFY"/>
    <dbReference type="OrthoDB" id="124397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:001208">
        <property type="entry name" value="Tetratricopeptide repeat domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="5">
        <location>
            <begin position="105"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="36713" checksum="2E9E5C21E179A322" modified="2023-09-13" version="1">MSTSLLLAPPTNTSPTSTLALSQLAPTYYKSQSGWSLPYPLSLFLNNESQEKWQSYENILLSCLRTGDTESAYLYLEELTDRFGPTNERVAALRGLYAEATAKTQEEVDNVMRHYEEILKEDPTSFAIRKRRCALLRSQGKTADAIQALTNLLDTSPTDAEAWAELGDLYAEQALYEQAVFCLEEVLLVMPNAWNVHAKVGEVLLLQARGNSAAVEQLRTLSDSMRRFCRSVELCDDYLRGYYGLKLTTTRLLEALSSTKKSHTAASDPVTGELAPPTIEAVTKLNEVATAKLAEIVRKGTAGEKGWDGYNASELAAARELLDQDTQKIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P885</accession>
    <name>A0A9Q8P885_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761270.1">
        <property type="nucleotide sequence ID" value="XM_047903704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P885"/>
    <dbReference type="GeneID" id="71984434"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04556"/>
    <dbReference type="OrthoDB" id="3626626at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13080" checksum="F57A7C3B750DDDD7" modified="2023-09-13" version="1">MALPTPPEPPTLDNRVQALPQELQDSILDLTIGIHDSFCTMAIDGKYKSPLGLQISRATRAKFANHYYGGGYIFHTGVFQTRVANLDLTRFTCRTYYWDEEGFYYKTIAIGLGPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8B5</accession>
    <name>A0A9Q8P8B5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761329.1">
        <property type="nucleotide sequence ID" value="XM_047904424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8B5"/>
    <dbReference type="GeneID" id="71985154"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05276"/>
    <dbReference type="OMA" id="NNRTADK"/>
    <dbReference type="OrthoDB" id="3634826at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="184" mass="19606" checksum="39A5476435CE94B3" modified="2023-09-13" version="1">MSAPPFKFPPAPADDDTTANSNTTTTLPLRALLNEGAATGHEPLQNKYATHPLVMFDNNRTADKNLVGAWSALMNLGRKGDAEKIRKIGNTTFGEKQFEGAISTAITHGSGDPPAEEDVAAAGFARVEVAPGLEDPSGDDRETAKKCLATAARAFGDLRQQGIAEKIDVVFKSAFGESIEEYWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8U4</accession>
    <name>A0A9Q8P8U4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bacteriocin-protection protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761961.1">
        <property type="nucleotide sequence ID" value="XM_047905679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8U4"/>
    <dbReference type="GeneID" id="71986409"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06531"/>
    <dbReference type="OMA" id="WSKLNKQ"/>
    <dbReference type="OrthoDB" id="10263401at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13376">
        <property type="entry name" value="OmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26216" checksum="1EE0BD32945BD5BB" modified="2023-09-13" version="1">MPAAELPVLTVATSKLWRRWLAQNSSNMPGVWLTVAKKGTTKPTSMTYADALDEALCCGWIDSRTRKVDEYTNSCRFTPRAPKGLWSKRNVGYIERLLQEGRMQPAGLAQVKAAKADGRWDAAYSAQGEPPEEFFAALKQNPGAQNMWDKLNKGNRWHIYFTLLNLKTEAGKAKRIQGFVEMLARGETPVPQKSAANKTSKRAASAMEPLDQVLPREAVVRKTRSGRNAPSYSDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9D7</accession>
    <name>A0A9Q8P9D7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pectate lyase</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_05777</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762202.1">
        <property type="nucleotide sequence ID" value="XM_047904925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9D7"/>
    <dbReference type="GeneID" id="71985655"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05777"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="420" mass="47267" checksum="6649302942616127" modified="2023-09-13" version="1">MNQHELAHGETSTAPGGRLEFIIIQTPDDTTKDTFRRQVRSHVTRVQHQRTRLSAITGVDHTKSEVHSDKHRIRRKKTDGQAKFRANRVEKITQAVKRPTPTGQDAVHTPPRASTDLLQVTKNTSPATAKAITDELARRAGTSVGDLRHGASGISALAVHETPGEIVTTPAVDSEQPALPGSPAAVNFSQGVMAARTFLFHDQDNVVGIVLKHLRFDLSSVLATYKVIVQMQSQDFERNQPDMPAMNPGSTWLRFWEYIWTDPAIMIGAVLLTVTFRLQMWEKPPDHPHWYHLLHLRGFFIRTIDAAFRDPVRCTCDQMLVAVALASAFEVKYNQNMDQGYHTHMRGLVKMVRMRGGLAQIATTDPFLERFLLWHVANTSALPRGQNVYYQQLSRTTAVIHPKADSHMFQMKELVVRAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBY2</accession>
    <name>A0A9Q8PBY2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS-type transporter dbaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764023.1">
        <property type="nucleotide sequence ID" value="XM_047909480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBY2"/>
    <dbReference type="GeneID" id="71990210"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10332"/>
    <dbReference type="OMA" id="FMGLYMP"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="288"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="50623" checksum="79B5D8BC4B8E40B9" modified="2023-09-13" version="1">MSHASTNSDLDHDINEKGTSRSKAGEDGVHLTEGQEELREAPEPTFIATDDADVTADGALGAVLEKVASSKPSVNNIKSVPNGGLTAWLQVVGSFFLFMNTWGVVNTFGTYQTYYEAGILASSSPSDISWIGSLQATLLMVVGSLTGPVYDAGYVRSLVSVGTFLVVFGQMMLSLSTTYYQVFLSQAVCIGIGTGCLFIPCVAILSTYFSTRIATAVGLAAAGSSIGGVIYPVVFYRLQPTIGFPWATRVIGFLMLATLAVSNAVLKVRVLPAGRRKFFDLSAWKEGPFTFFVLATFIGFLGLYTPFFYLQSYAIQTGIADPDLAFYLLAILNAASTFGRVIPNLIADRIGPFNVIIPCTLATGILCICLAPTRSVAPVIVIAVLYGFFSGTFVSLPATIYVHITENRGLIGTRMGMGFSCTAIGILVGTPISGAILDASSYTYVWIWGGIMTIVAAGILVIARVCKGGWKIMKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCC8</accession>
    <name>A0A9Q8PCC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764168.1">
        <property type="nucleotide sequence ID" value="XM_047909175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCC8"/>
    <dbReference type="GeneID" id="71989905"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10027"/>
    <dbReference type="OrthoDB" id="10657839at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="384" mass="42359" checksum="45BC1A925D1C415F" modified="2023-09-13" version="1">MDQSDISRLRDLIYRKDELSGLISKDENSLLELRNQMSDRRATLQHVEKQLAEMLAFKPVQPQQKGSVSSPAESDSIAVTPAPGPTRTISTSKSPSPDSQQHATVPTKQIAPRPDLQRHDDPLKDPSDYIKSIDYVKEKNNDRRLMLHRDLPMIVRLEDGWNEIWCHVCGANASSRGNAADGVVPFQGVYGLHCHIASMHGVAGKKTFVKDLWKICGRYLLSEKEVRKLRQWKVTVKIQSSGSNGLRGKGKAELPAPAPAANDVGDEEIMNEYDSSDEEDAVAAPGYLGHILQEQTHLTGAVALTNHQNGFTPVNGNTAISTDSGYGSKSSPTKRAAESETSSVLEDSGGDGVAERVKRHRRTETPRRSYTDHFEYGDMGEETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD48</accession>
    <name>A0A9Q8PD48_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED17</name>
        <name evidence="10" type="ORF">CLAFUR5_09837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD48"/>
    <dbReference type="OMA" id="AAETKYW"/>
    <dbReference type="OrthoDB" id="5319830at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="43"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="615" mass="67335" checksum="1B5F022C14E1995B" modified="2023-09-13" version="1">MTTSSLSFKPWARDNDDKTALSEVLARVNFERGHFRDINEASLLEEIAAEGEHSSSEGEEEEDDDQDEVESNNKKQQPAATREELWAKRHEMIRHAGDAHNDIMTALDSISLLETKYLPAQARVTMSEALKSAKPPMGSMGVDIWDPAVMKPDPARVAQDNLLATKVRMEGLQQSADGLLAAAARLQKDVRQETSYWEEILSVADKGWSISRMGSSHILGVRFGFQGSAKRFENRDVAALIGTPDGGVALERGVGTKPKAVRVLARRGGRIVGSSKLPVVLDDEETTLEARIRHARDSVYDEELFYEMIRETSDLTSMGVLVRGSTILFPGSGQDSTQLELELLPLDQDNSLPLDATSESDFLAQATLVTARLLLGQAHRDRMNEKKDVPPPLGTTEVNTKQQALSILRTLMLLSQHKAAVDQLNAYVDSMCKLLRKLGASAESQMAHMGLPVPADGIVSTEALITSLTRPLLAESHIWLIVSDEKTLDLKLGIETSKANSLGSIFSIHPPSSKRFIVPDIDTLLAAANDFLALGLSHVLKEEAGAGWELNDRDGRLTRPDAEDGRDVLLFVVGHEPPTITLHAKTTGGRKQVAWKLDSTGGAKSLKDVWQDLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD61</accession>
    <name>A0A9Q8PD61_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_10030</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764664.1">
        <property type="nucleotide sequence ID" value="XM_047909178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD61"/>
    <dbReference type="GeneID" id="71989908"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10030"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="39274" checksum="038C5B6D03BE277F" modified="2023-09-13" version="1">MTTFVSERAEGARAKNSSKRLGMQGIFPGLSVPVLVIRQTKEYITQRMPSIYKTSGLGQFLFGFDDETKAKYPHCFTDHNIDRHKCQRVVPMKVLSLGMGRTGTASMKAALTKLGYPTAHGFDMHSNPKDCEMWQEAINAKYFGDTSITLDRAFWDKLLGHVSAVTDMPCNMFGPELIAAYPEAKVILVERDVDKWYPSFEHALIEGTDSPFLWHAIQYLDYKAAHMSPTVWRGMMNGQFRAKDSKEWRANAKMIYTEHYQEIRTVLKDQPERLLNYRLDDGWKPLCEFLGQPIPGGPFPKVNESEQHDEFVATVITIMGRRLVGNILRIAMPVVVGLVAWRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE67</accession>
    <name>A0A9Q8PE67_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765157.1">
        <property type="nucleotide sequence ID" value="XM_047910061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE67"/>
    <dbReference type="GeneID" id="71990791"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10913"/>
    <dbReference type="OrthoDB" id="3650741at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="199" mass="23650" checksum="1D7A68B1962D0DF5" modified="2023-09-13" version="1">MLGLKHRLEALPQELYDMIHDHTFTILPTYQLIAATYKPPSILQVNRSIRTGLLPTYYSTTTFEFISPGIYEKWWSRQESQVSDLFANHRPDSINGTLCRIDTTDVEELSSGVNILLDQMFRQWFDMPFIMPEVEFVDEMRVRLDLQQLWHLKAYRLYCLGQRHGDTGTLQRPSRSRYWRFKLTRCWKKMANVLRGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEG9</accession>
    <name>A0A9Q8PEG9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEG9"/>
    <dbReference type="GeneID" id="71991244"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11366"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="89" mass="9946" checksum="6E0D3FA3FD0817FD" modified="2023-09-13" version="1">MRQAFIKAHRIIPASSSDWVLKACAGGFKEGQSPTVTLEDDDEDDVASVIEFCYTFTYAEARPEDCGPMTKALRMFSMGDKYLIDNLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF59</accession>
    <name>A0A9Q8PF59_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765653.1">
        <property type="nucleotide sequence ID" value="XM_047910185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF59"/>
    <dbReference type="GeneID" id="71990915"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11037"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="13862" checksum="5940F8F26C8E219E" modified="2023-09-13" version="1">MGTSSTTHTSSAASHIPRQLSTNIQSDIFKQSRATFKSSDPNRRSILAMSNNRNIEDKASPLSVEGKPTEYLNSAANGKEENMRASSQHAQKAVEVQDKNHAEDWLDAQRVAFELAMGNRDSTRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFC4</accession>
    <name>A0A9Q8PFC4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765801.1">
        <property type="nucleotide sequence ID" value="XM_047908284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFC4"/>
    <dbReference type="GeneID" id="71989014"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09136"/>
    <dbReference type="OrthoDB" id="67027at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="9"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17412" checksum="A2BD106807739D5C" modified="2023-09-13" version="1">MANRFREAKTELEIILGHNFVNEDILREALWAAGPGSVGHRLFPEGNKRLALVGDAALKIALVHHSYTKGRSRGEADQTTQSALCNTKLNSVGRANDLGQYIVLHNINSTVTKNVMATTMEALFGAVFEDSGMDLEAVRRGMVGFGLLELWEPSSSVGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGD3</accession>
    <name>A0A9Q8PGD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PI-PLC X domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766371.1">
        <property type="nucleotide sequence ID" value="XM_047908419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGD3"/>
    <dbReference type="GeneID" id="71989149"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09271"/>
    <dbReference type="OMA" id="IEDWPTI"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF140">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040466357" evidence="1">
        <location>
            <begin position="16"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="37757" checksum="B7ABE3711317A95B" modified="2023-09-13" version="1">MFVVLALLLSTLSLAFDQVPLSPSSIPPRYQLDGNDDPVPKQPGQRIPVPALYNHRYSEQTFIGAHDAVAVRTAENGWTLSGNQYFNVSTQLRSGVRLIQAQGHRDPTGSDEIRMCHFNCALMDGGSLHELLRDVKDFLDQFPHEVVTLLFVNTGPPLEHWVKAYYDTGLDLMSYMPPRTKRWGNMRIEDWPTIADMVSSNQRLVSFMDRGADEYEAPFLLREFDYIFETNFGIERPSQFSCTVARPWWIVGGYPDRLSLVNHFLYAKFLGFRYPNATQANTTNAAGFHEGELGEHAVRCRSLYERRPNFLLVDFFNEGDVFDVEFGLNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGW4</accession>
    <name>A0A9Q8PGW4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-acetyltransferase PaAT-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766558.1">
        <property type="nucleotide sequence ID" value="XM_047908381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGW4"/>
    <dbReference type="GeneID" id="71989111"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09233"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="31"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="522" mass="59548" checksum="65F5007F8E8A1394" modified="2023-09-13" version="1">MQFTPLSWFQKCLGFFHGWPPKELDGSRETAWLDGVRGLAAFLVVMNHYDLEWLSIFAYAPFGARVLADKNVDGVWYYKEGDRLWEPYRLPFFRIIAASGSAEVAIFFVLSGFVLSWSPLGTIRANNQEKLFGSLSSSLIRRWFRLYLPCFIVSVFYLINEIYVSWHGVIGMFEEIWKFIEESRRWSNPLQGTPATSLFTVNTYNYVMWTIPFEFSGSIFVFTLLLAIGRTQAFHRRMVCVILTTMYAGWQTYWGLWLFGMGLALADYVRWRGGFNKLSQQTGPIARCAWILVFVLSLLLMGYVDESDEFTRPGYAWLSYIPIPPGYRGMVGEGRVWFAIAGFLFVASSCHLTFVRRFHETKLIQHLGRISFMLYLIHILINTRVSLPLRGALYDALCENRSQDGFDHVFISGPFTNVFIWLVVWLISVPIAMSCAHFLEIFVDKPCNEFGKWLDDKFVNGSGRVKLQSGQEEAGLLSQIPLDQLQPGEASEVAEPLLSPKFSLESASTSSIDHGTEVPGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHI9</accession>
    <name>A0A9Q8PHI9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATPase WRNIP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_12227</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766897.1">
        <property type="nucleotide sequence ID" value="XM_047911375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHI9"/>
    <dbReference type="GeneID" id="71992105"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12227"/>
    <dbReference type="OMA" id="RIILSQC"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3710.10:FF:000005">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            <dbReference type="EMBL" id="UJO22726.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI34</accession>
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        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_12485</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
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    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
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            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="DUF1720"/>
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        <property type="entry name" value="EF-hand-dom_pair"/>
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        <property type="entry name" value="EF_hand_dom"/>
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        <property type="entry name" value="EH_dom"/>
    </dbReference>
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        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="19">
        <location>
            <begin position="191"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="19">
        <location>
            <begin position="466"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="20">
        <location>
            <begin position="499"/>
            <end position="534"/>
        </location>
    </feature>
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        <location>
            <begin position="1431"/>
            <end position="1448"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="971"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="64"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
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        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
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        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="819"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="855"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="925"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="990"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1051"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1061"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1084"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="1169"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1183"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1203"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1232"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1257"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1280"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="1307"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1352"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1372"/>
            <end position="1423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO22805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1463" mass="158449" checksum="769113886A803576" modified="2023-09-13" version="1">MFSGSNSYLGGGPSGRPGQQQYGQPQQFGGQQQQQQPQYGQQQPPYAQPPLQQQYTGFPQAGLQPQATGFPGQQPQQFQQQQQPQPQYSGFQQPQPTGFQQPQPAGFQQPPQQQQPQIQVAQPTGFQQGQQNAFQQQQPQQPMRPQATGMTSNDMANSFRGISSAPTPSAPAPKSGNKIPSIRLSFITAQDQAKFEQLFKSATGGDQALSGEKAKDLLIRSKLDGNSLAQVWTLSDTTKSGQLLFPEFALAMYLCNLKLTGKDVPSSLPEKIRNEVSSMVDIISFGVGDEGPAPTPSSNAPNFNELPKIQQPQAQNPSNQQLLTQLTATPTGFQVPQATGFQQQQPTGLQPQQTGYPGGMPQAQGYTGPRPPMPPMPTGMGQNLSPGFGLAPQQTGFGGGPMAAPLNAQPTGRPGQWGLVNAPASGLPNLQALQQQMMPQPGREAGFTTQGLRGNATVPWAVTKDEKKIYDDMFKAWDGFGKGYITGNQALEIFGQSGLEKAELERIWTLSDPHNKGRLNLDEFAVAMHLIYRRLNGYPVPNTLPAELIPPSTRNIDSSIGTMKNLLSQDAQTRKSTGAFLQPQRTGVSYMKSRSFQANGTPGRKDATVFKNNDDDVGYRSSARRRVGENGRSSSPAQSDTSSITADEMSIDQLKKTIREKQVLLDAMDFEDEGNADEEDALDRKDRKESEELFRRIRRIQEDIDSHPSSAFKTGDSDAERRALQRQLRGLQDRLPELASHVRRCEKAIADAQLELFRLKDAKANPSSAAAIVGTGPGGAVTESDRLKARAKAMMQKRSAALAGKKVDDGDDGSGAAARLEEEQRRVSREREDNEKMVRDVEESVTEYSKGLESSLKEGGESASDEHERRRWDDGLGVEDEVKDFIFDLQRSSRSARVRNEEKAQPRASAREPVQDDSRTNTPVSRTDSPASSRAAASTPQTSGSSYSSYRTAEERAAFIKQQAEQRMAERLAALGLKAPAKSGESAAQRAERERKEREDRLRQAEEEDAKREQERQARLRGESVAPPTPAGSAGKPKPPPPAPRKKRSESLQGQDQANSEAKRAEQEIKEQALKEQQAAMAKETNDMEHEEARQERELQKQREEAEASLKALEEQVKAGKVKKAEEKKRREASKKEAQEKESRLAAQRAEIEAAKEKERQLRLQLESMGDDDSSDDDDVERNTPTESTPTQSMELPRVQEPPSSPPVAPPLPSAAAPPPPPMPGSFDTGMPSPAVSVTSPPSESKNPFFKCMNQQPAASPAATSPEAEKKVDTNPFHRLTQQDLVNQQALPDPAAPPSRKTAKPADEDDWSVVDSSDDDDYEDQPQGGSAKQLASILFGTMAPPRPLSAMDSPTTASGPNSPAPGKDRIASPPPPPPMPNSGAPPPPPMPNMGAPPPPPMPDSGAPPPPPGPPPPPALPAGPPAGGGGMDRSGLLGQIQAGKGLKKTVTKDRSTATTAGRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI72</accession>
    <name>A0A9Q8PI72_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12445</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767231.1">
        <property type="nucleotide sequence ID" value="XM_047911593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI72"/>
    <dbReference type="GeneID" id="71992323"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12445"/>
    <dbReference type="OMA" id="FLSWTRM"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="21"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="15297" checksum="42784451E4E7B9EA" modified="2023-09-13" version="1">MSLLRRLFHSPSLPNTGSLARDLLASERTFLAWARTGLGFIALGVALEKVEAFAAISPTLLHLEHSRTKLAAGVLVGSGSLCVAHGTTRYFAVTRALERGVFRPNVAGVTMMAAATMGIAFAGTMLVLENEGGRNKRKDAGTQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ25</accession>
    <name>A0A9Q8PJ25_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767930.1">
        <property type="nucleotide sequence ID" value="XM_047912163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ25"/>
    <dbReference type="GeneID" id="71992893"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13015"/>
    <dbReference type="OrthoDB" id="3650294at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="18172" checksum="30354EBC12BFA662" modified="2023-09-13" version="1">MSDPSLSLLMPAYQRSLQSKQSEQSKDGTIVFEQSQTALRMEKNSRAVIDSINSRCYSAATSLVATTYRSDIDDLSKTKSYSDSKKQFQQISQKHPEYHVEVVNVSADVDEESGYAIGRPANVRRQSVSVVEWMRRDGQWQYYNATVVRGQDGPDVVWHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJA4</accession>
    <name>A0A9Q8PJA4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-fucosidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767813.1">
        <property type="nucleotide sequence ID" value="XM_047911892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJA4"/>
    <dbReference type="GeneID" id="71992622"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12744"/>
    <dbReference type="OrthoDB" id="2848340at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054363">
        <property type="entry name" value="GH95_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084:SF3">
        <property type="entry name" value="ALPHA-FUCOSIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_95_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 95 catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="13155" checksum="097BFA5DFAC5DD93" modified="2023-09-13" version="1">MNHCHTDQTGLGPLQTPLWEYMAQNWAPRGAETARLLYNASGWVVHNEMNIFGHTGMKGDGDISSEIWANYPIAAAWMMQHVFDNFDYNSQDVAWLRSTGYPMLNSISQFWLSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJV7</accession>
    <name>A0A9Q8PJV7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768174.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJV7"/>
    <dbReference type="GeneID" id="71993210"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13332"/>
    <dbReference type="OrthoDB" id="3629888at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="18956" checksum="3A70A2AF06E882A9" modified="2023-09-13" version="1">MATTQKASLLSLPRELRDTIYSHLYTGQDVDITQSGHAARKTALLGTCHQLRAEAAESYYTKVIFFVPLLADPTRWSLKMRDEHARLVTYVRHDQDQLSARPSLYHSLEFLIMRCDEEDDRVDWAGVLRMYWYIEDECDDEDEGVGWARLWELPEEAKELME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJW9</accession>
    <name>A0A9Q8PJW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerol 2-dehydrogenase (NADP(+))</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13317</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768143.1">
        <property type="nucleotide sequence ID" value="XM_047912465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJW9"/>
    <dbReference type="GeneID" id="71993195"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13317"/>
    <dbReference type="OMA" id="TWHHRVQ"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="33663" checksum="3E6C9B420C214A7C" modified="2023-09-13" version="1">MGSAPPQLTKRTYKLNTGAEIPAIGLGTWQSPPGQVEKAVEAALKHGYRHIDTAAGYGNEAEVATGWKASGVPRGQFFLTTKLNNPDQGRVAEACDESLKRLGTDYVDLFLMHWPQPVDPSDASGKKALENWDFKKTWAEMQKLPATGKVKAIGVSNFSKHHLEELFADSSFKVTPAVNQVEVHPCYPSFKLVDYNTSKGIHTTAYSCLGSTDSPLYKNDTLAKIAEKKGKTVQQVLLQWGLSRGYSVIPKSTSPSRIEANFALDGWSLDDDEIKTISSIKDRFKVCDGTFLPYDGEKAKLFVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJZ5</accession>
    <name>A0A9Q8PJZ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hit family protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768178.1">
        <property type="nucleotide sequence ID" value="XM_047912085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJZ5"/>
    <dbReference type="GeneID" id="71992815"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12937"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
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        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="25"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="110"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="24670" checksum="3A05E75862D9B9CE" modified="2023-09-13" version="1">MPRVVVTPEQRQRQAQIASMAANCIFCKIIKGDIPSMKLFESEKTLAFLDINPLAYLVIPKHHGAKLLDIPDEHLFELLPVAKKIANATGVENYNILQNNGRAAHQEVDHVHFHYIPKPSPEEGLQIGWPQQKPDMEMLKKLLEEIKAKTVMQREKFGVESGRAEGEEAVIEDQYQLGQMEQRRQNDGGKIEWMGTLLREMIERGVVPKRRLSDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK33</accession>
    <name>A0A9Q8PK33_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mRNA 3'-end-processing protein RNA14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="6">Nucleus and/or cytoplasm.</text>
    </comment>
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</entry>
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</entry>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="210"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="256"/>
        </location>
    </feature>
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        </location>
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            <end position="394"/>
        </location>
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            <end position="425"/>
        </location>
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            <begin position="503"/>
            <end position="525"/>
        </location>
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            <begin position="48"/>
            <end position="530"/>
        </location>
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        </location>
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        </location>
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    </evidence>
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        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24032.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="61517" checksum="D03FCFE5F2D166F1" modified="2023-09-13" version="1">MAARTAGGNSAFHNFHNDYAHVADPNERRRLALAEIDKAPFGWYHVRACAVAGIGFFTDAYDIFAIGIVTTCLGIVYWQQDGGKIPVSADTAIKVATSGGTVIGQLGFGFLADVVGRKRMYGLELIVIIFATLAQALTSNSASMSLVGTVIFWRVLMGIGIGGDYPLSSIITSEFATTKWRGAMMGAVFAMQGLGQFGAGIVALIAIAGFKESLLSARSATNSQAACDGVCLIAVDKIWRIIIGMGAVPGCIALYFRLTIPETPRYTFDVSRDVVKGGSDVKAYLSGTAEGVPDEITRVTTMKESAPHLEVPKPSWRDFGSYVGTWKYGKVLFGAAASWFLLDVAFYGVGLNNSTILQAIGYGKGTNAYEFLYNIAVGNIILVCAGAIPGYWVTVALVDTVGRKPIQLIGFIILTILFCIMGFAYHKIGTSGLFACYVLAQFFFNFGPNSTTFIVPGECFPTRYRSTCHGISAASGKIGSIIAQAAIAPLRTRGATSTNASPWLNHVLEIFALFMLLGCFTTLLIPETKRKTLEQLAGEVPGTPEYDPVLAGDRASRAPSDPSSEHIPAEKGDHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKL5</accession>
    <name>A0A9Q8PKL5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein protein MPP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the MPP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768521.1">
        <property type="nucleotide sequence ID" value="XM_047912961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKL5"/>
    <dbReference type="GeneID" id="71993691"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13813"/>
    <dbReference type="OrthoDB" id="445326at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017300">
        <property type="entry name" value="snoRNP_Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="118"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="669"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="719" mass="81526" checksum="A3B661C836FA4851" modified="2023-09-13" version="1">MAATTTPSSSNKRPKTMATTSQFLQSLASRPVDFLQPTLPLHTDAVAYLKHILDPIAKDVATQQQERLKQERKKRKRRGEDRDEEEVLRLKQIHTDGFGVEQIWEQARRVIDAAREEAQREYAEWTKKPEAQKSDEDVNLADQSMFDEDDLEDEDLGVEGEDYEIEGVDSGEEMYEGSDVTGDDEKDQVLEDDDEDIDMDGHDDFDDMEDDEPEEEQPAEEFVADKFGLNDGFFSIDDFNRQSEFLEQRQVRGEDDGAASDEEDIDWAADPTQAVATVDTEDAEAGADEDEEDGPTFGDPDAESEDEDEEVEEGELDGMGGMANTNDVMYKDFFAPPAQKKSKKDKKGRLNPHNFPASAALNPQNDEEREEDMQRTMEAVHRDLFDESEEEPDEHDEEQDPADPRSRRSAHERRKAAIAEEIRKLEAANVAKRDWQLSGEARATDRPVNSLLEEDLEFERAGKPVPVITAEVSESIEELIKRRILAHDFQDIPRRRPDDLATGKDGKRGRLDFELDNNKSKKGLAEEYEEEYSKRTDPNYVDVKDEKLQKEQKEIEALWREVCGQLDSLSSWNFRPKQAAPQMDIRVDAPTITLEDARPNAGGEVATSQLAPQELYKAGEASNKKEEVVGKSGLPKAREEMDRDERKRRRRREKERIRKAGTNEAPETQSKKTREKNGVIGDLKKGNVKVIGKKGTLTDVEGRNAVERGSGQGAGQYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKQ2</accession>
    <name>A0A9Q8PKQ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768535.1">
        <property type="nucleotide sequence ID" value="XM_047912729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKQ2"/>
    <dbReference type="GeneID" id="71993459"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13581"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="17703" checksum="B767D46C76EDA4BD" modified="2023-09-13" version="1">MTLDEGSLQAKYDLVNLSVITSTQISSRTLAVLAQFSPSGHEIENNDPATIAAAGNNNGRPVIVALTARANATNKLISIVEIAKRELTSKKVKCFQYNALGSEIVEIERKSKSGNDESESDDAFETMGAVPLSEKKKRSMPVMTVYLAITPIRELRLAYGEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLQ2</accession>
    <name>A0A9Q8PLQ2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769114.1">
        <property type="nucleotide sequence ID" value="XM_047913056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLQ2"/>
    <dbReference type="GeneID" id="71993786"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13908"/>
    <dbReference type="OMA" id="NARAWYS"/>
    <dbReference type="OrthoDB" id="2306919at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="23979" checksum="C9E2AA7BC3E2572F" modified="2023-09-13" version="1">MTSIFPARSEISFDSRLTTLKSAPAPLLPPGKSWDPALTDKISTLYLHPALEALLHILNLDLPSSHFLVRHMQSSPEHTAMYLHGILHRIEGDMDNARAWYSDVSESEVFARIWGEASEDEKGEVSDVEKKVPPQSKARDFLDGVEGLIKKGAGSREELESESRREVEGVLKFCMDKFGTERREDASKVWVQPSKEISEKGQDMVIGGEGIRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLU4</accession>
    <name>A0A9Q8PLU4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769123.1">
        <property type="nucleotide sequence ID" value="XM_047912928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLU4"/>
    <dbReference type="GeneID" id="71993658"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13780"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="12356" checksum="586506712DECE4F7" modified="2023-09-13" version="1">MSHLRDRDLQRFCRVTVHRRGDFEGKNRDRDVEIYELLDARGGWQSHDALNDVNIVQILVPETSGALGLNERWVDGDGSKDELKKGVFADLDAAKAVPVMKEQIARLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMR7</accession>
    <name>A0A9Q8PMR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769767.1">
        <property type="nucleotide sequence ID" value="XM_047913246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMR7"/>
    <dbReference type="GeneID" id="71993976"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14098"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040223137" evidence="1">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="16951" checksum="F3FC804F11BCD37C" modified="2023-09-13" version="1">MQLHHITAFIASLALTANAIPVPDDGPAMEASLQARADQANEPYDRQVHPDELDALLTHRDLEDFDVDAPLTRRDAEPEESHLTKRFLDNDSYDLDVYDDRIFWRNGRRNFFGNRGGFYGRNRGVRFFNGRRGYGYNYNWNNRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PN07</accession>
    <name>A0A9Q8PN07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PN07"/>
    <dbReference type="GeneID" id="71994311"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14433"/>
    <dbReference type="OrthoDB" id="3938166at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040500257" evidence="1">
        <location>
            <begin position="23"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="13576" checksum="CAACD5E77C92C610" modified="2023-09-13" version="1">MPTQSILLSLLSLTTLTTLATASSMKVQYYTDGGCTSYAVETYPFANWDCYNYSWGGSNSANIAACNPDYQGGICSCTFFTSSNCGGQGHTAEWSKVAREVASMEYVDQSVVSDTVNVSRFHGLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQC6</accession>
    <name>A0A9Q8UQC6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial import protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763049.1">
        <property type="nucleotide sequence ID" value="XM_047906681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQC6"/>
    <dbReference type="GeneID" id="71987411"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07533"/>
    <dbReference type="OMA" id="KPPTFWG"/>
    <dbReference type="OrthoDB" id="5529571at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14530" checksum="CFDA921F61667A8D" modified="2023-09-13" version="1">MSSRDLSESQTTFPSDSENYDANHSNQDSSDEPTSDSSSPMILYQPPTIWSLMRGAAINLLLPFVNGLMLGFGELFAHEAAFRLGWSNTKIFPTHRSQAHKIGPGIEIKDDPVERRRRSGREVDAYTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQG2</accession>
    <name>A0A9Q8UQG2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763109.1">
        <property type="nucleotide sequence ID" value="XM_047906387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQG2"/>
    <dbReference type="GeneID" id="71987117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07239"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17883" checksum="900CD996276A34AB" modified="2023-09-13" version="1">MSSSQKPSTPWPEQTGVWATYDLHCHCGAVRFNMKVSPPLFEDEAEGKGIYPVTECNCSHCERQGLQVVHPLQKNVNLTQGEDELTKYYCGNKMNPHLFCKHCGSVMMTDLTALGKIFPGELRYTVNVRMLKDYDVSKLTIKKVEFMKDMPPKYSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR72</accession>
    <name>A0A9Q8UR72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Quinate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07007</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763786.1">
        <property type="nucleotide sequence ID" value="XM_047906155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR72"/>
    <dbReference type="GeneID" id="71986885"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07007"/>
    <dbReference type="OMA" id="QKESIRW"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF25">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G12950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="17"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003346"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="511" mass="56339" checksum="3EA07A569A90187A" modified="2023-09-13" version="1">MAKLGGTRLGAFRAYFFGFFICTAGFLFGYDTGIVGGVLTMASYKEHFGYTDNTTVSAVMVSLQNVAAFLAACTIFPVSERFGRRKTIMGAMAVFCTGVVLQLIPSGSLVCFYIGRFVSGLGLGAATATVPTYNAEQAPKEIRGKLGAGMQLLFAAGVMISYWVDYGTVRGLAHSNAEWQIPVGLQLVPAAVLGLGLIPQKESIRWLAKKGRNDEAWEALTWMRADSGPEVKAEFNEIKTGIAEELRATEGFRKRELLEPANRYRIALAFGIFLGQQCTGMTALAYFAPQFFKLLLGAGDKNLLVTGLFGAQKFVTVGTYIFLFSERWGRKPTLWIAAILMSICFIIVTVVNKTTLAPVDNKTTAAGIATVAMIFLTNTIYQFSWGPLPWPYAAEIFPSRIREFGTGVGVSTQWLFNFLFSLTTPYMIAAWGTYVFVFYAILDLVMATLVFFFLKETRGKTLEEMETLFHSKAAFDNEAARKKALESSSEDRFSDLDNQVQLTKNDSEFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URF2</accession>
    <name>A0A9Q8URF2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Xyloglucan-specific endo-beta-1,4-glucanase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8URF2"/>
    <dbReference type="GeneID" id="71990193"/>
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    <dbReference type="OMA" id="HTWNLYS"/>
    <dbReference type="OrthoDB" id="95118at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
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    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="XYLOGLUCAN-SPECIFIC ENDO-BETA-1,4-GLUCANASE A"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
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    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040435681" evidence="3">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="26451" checksum="6D8B671BFE307B38" modified="2023-09-13" version="1">MLRSLYLAAAGLAAFAVSTPTKTLVPRADLCGQWDSVVTGSYTLYNNLWGISGATGSQCVTLDSLSGSTIKWHSTWSWFGGSNGVKSYPNVVTSGGIGKQLSALRTMQSSWSWTYSGSNLVTNVAYDIFTSSTAGGSAQNEIMIWLAALGGAGPISSSYDASGNPVAVATVTLAGRSWRLYEGSNGYNYVYSFLPANGASVASFSGDLKVFINYLTANRGLSTSQYLISAGAGTEPTSGSGARFTTSSYSLVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URI5</accession>
    <name>A0A9Q8URI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764144.1">
        <property type="nucleotide sequence ID" value="XM_047909428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URI5"/>
    <dbReference type="GeneID" id="71990158"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10280"/>
    <dbReference type="OrthoDB" id="3944128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040219129" evidence="2">
        <location>
            <begin position="25"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="654" mass="68571" checksum="C62A03220A35D219" modified="2023-09-13" version="1">MPRHHAAVLRLLLYLQCWILAVYGTGDATGHAHDRLGLAYAEQCQAQLFAYRHASLSYYSVQPSSTSYFTSTIVAPSWAPGTTSIASLTTLCDGHPRVVGSTIRTEGPSTNLTNVYTNTNVYPQSTGYKPPPCSIGPNDCALLYSSWTRRYSQVSTQSGFAGLLNPPCTTSTPSMSYSTNSAGKECNNCQVAGSKARLLYWPITTVPGSGNLCNKTAITIPGTRTADGPNTFVTAGVTITSPTIGVSIASLSRVDGCGSTIATTIIPVNPEEISSVRGNRAMFTHMPFNFADLNWHCPDGEYVTDDGHHNCYQEVPAAAYFEGTSNWVGLDAMNVDWRTQKNLTIWNDYHPQLLPPETMMEAVHSIWGKGCNIHPDGIWDPPIALQEATSVVVPTNPYAVPTESQQTSTSTAAPATYTAEYATQTADSGTSTSHEATASTAYVHESAHPAPTGGSPAEHDQPAHSVSKPPSHGGGEHDQGNNGGTGHGASSSSPVVVIHSVTYTRQIQSNGAEVLTNAQTHFTVPKGTAGSPPVVIISQKTYTVSTAPGEGAGAGYYLIGDGTTYGSDGQQTSEPSVHTQSTSGTDEEDTTLASDRRSGPTSTSPSGNAATTQGSNQPSSSAALQGSAASGYGMPSFMLLTTLGVLVVLTLQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URL2</accession>
    <name>A0A9Q8URL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764234.1">
        <property type="nucleotide sequence ID" value="XM_047909625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URL2"/>
    <dbReference type="GeneID" id="71990355"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10477"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="13334" checksum="FD0E93FEA2F23FF0" modified="2023-09-13" version="1">MVNYLSNHHCSYRGCNRGNLQSRHGGVCADHQVTCTRSGHLEVHMKGTDCQKCADQTRRDEKKAKKEAEKRKAEEQKEKEAKAAKDKARSERKPKHNKHNKKDEDREGAPRLERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URY0</accession>
    <name>A0A9Q8URY0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764564.1">
        <property type="nucleotide sequence ID" value="XM_047909679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URY0"/>
    <dbReference type="GeneID" id="71990409"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10531"/>
    <dbReference type="OrthoDB" id="3645296at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="27084" checksum="501821627FF4147C" modified="2023-09-13" version="1">MASASPQEQSECLLMALPAELRNEIYQYVLDGEAQKCRTRFKVRFTSKCHARRGRQEPALLNTSSAIRAEALPMFYALNKFELTFAITQLHDATEWVSILRQQCGNGPQGRGPLGGISLNITTCSWVHVASLLPLAEFAFEYALVLGQVKPPAGMVHLSKTVHDIAALGRKAKKQGKDLEWLKVRFEQVVGRHLDKKHAKTALAKDEARQELLAESLKLKEVEVLGGPVDDSPRQTRSMLSGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USH7</accession>
    <name>A0A9Q8USH7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_10919</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765153.1">
        <property type="nucleotide sequence ID" value="XM_047910067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USH7"/>
    <dbReference type="GeneID" id="71990797"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10919"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040182312" description="CFEM domain-containing protein" evidence="16">
        <location>
            <begin position="21"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO20787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="354" mass="39548" checksum="55670487D3FD6E19" modified="2023-09-13" version="1">MKLLWSLIFVIIAFIFVAEAQDTTLDEALSIIQSMPQCGSSCLLSGIANSTCEVGDIPCSCHNKELTAKVQACVLEACEIKEQLTTKNRTGTLCQRPARDKRGPDQRSVIVGLTFSCLAFVLRIMSKINSPCTNNQGSSHTLWWDDAVMAFAVGCAIATSYSAIPLNEHGLGTDVWSVPFDDITTLLKIYYWAEDVYLAALPAVKISLLRTYLRFFPDLRFRQACYVVMGLNVAHAIAFVLILVWQCVPIHLAWERWMYKDSSQMPGRCSDINAQGWASAAANMVLDVCTLSLPLPALWQLQLNKRKKFWLMLMFSVGFSVTVVSIVRLQVLVRFGNSQNLTWDYTAVGYWSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USU7</accession>
    <name>A0A9Q8USU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO21774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43371" checksum="96C629A27F60A5AC" modified="2023-09-13" version="1">MAKTKIISTAPGGLDYSKCKRTELDTFYKQRLHKDVPKGVNKPELIQMLRRQDQDPGTFRFLDLPAEMRNAVYKELLILPRPGSRRRGSTYQPAVLGLCRQVHSESPGILYGENEPEIIIEVAHHTAHSYPRELQRHCTIPLFSKITHKDCHQFYPWSDASRSLRLEQLTRFHSSSVQINIGNQQVGSGLSSSCASELLIAVNQLLYSLCDFLASSPQKRTITSKLNAQTDLVTTQELHQTLWPVTRLGSATTINFVNVPQKVQQLLLAGCVTAGASPSLLEKLSQAEPRAKAISKEIRKLGSEKQAQIQSEIRAWYNTTYDINVALKRTQMMDKTTEKTLRQRIRTFEKTPAGKLADLLAANIGERIKDMENIRADVESKRGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTE3</accession>
    <name>A0A9Q8UTE3_PASFU</name>
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        <submittedName>
            <fullName evidence="8">Trichothecene efflux pump TRI12</fullName>
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        <name evidence="8" type="ORF">CLAFUR5_09679</name>
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    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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            <dbReference type="PubMed" id="35471194"/>
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            <strain evidence="8">Race5_Kim</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="PRMKIQM"/>
    <dbReference type="OrthoDB" id="4161376at2759"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
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        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
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    </dbReference>
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        </location>
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    </feature>
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        </location>
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        </location>
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            <end position="534"/>
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            <begin position="48"/>
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        <source>
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    </evidence>
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        <source>
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            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
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            <dbReference type="EMBL" id="UJO21702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="569" mass="60689" checksum="61B67DFFD2A05242" modified="2023-09-13" version="1">MADDKSIESHHDEKVMPDHLEDLERTHTKIDVIHVTQKLPYGEINFIGTYMACLLACCASFAGFIMPITSLQLIERDLGVSENAVWIALGWILLSAVSFVLLGRLSDIFGRRWFFTGTTISALIGCIIGATATNINVLIAASVFPGLGSAGQLSANYSLGELVPVRHRFAINGFIFLATLPFSGLGPYLARLMIVNTGPSWRSIYYLIIGLNAASTVCWVLFYHPPKFQGLHRDRTVREELAEMDFGGIFLYVAGFFLFLLGLAWGGSVHPWTSAYVLAPLIIGFFTLVGFLFYEMYMGLRRPLIPMHLFKNKDFVIVNILSAVGGVVYYSANSLVASCIGGGVCAGQFLGSWLAVPGGMLRLKLIFVSCGLCAFIAGLAGATNSQAIGSALAVCGGLCVRLLEVVVSTVVTIVIDDQSEIGTAAGVFDGIRAAAGVLATAIYSSVLMNKLAGYTKSTVAPAVVQAGLPLESLPAFLTALSSGSLPALEAVPGVTPAAIQAGVATFTEAYAKSFKVVWLGTLAFGLLAVIASIFTTNIDDRLSHDVVRRLDGGKNTDLENGEKLEKLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTV9</accession>
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            <fullName evidence="4">Cysteine-rich transmembrane CYSTM domain-containing protein</fullName>
        </recommendedName>
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    <organism evidence="2 3">
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
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        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12265" checksum="165E7DBFD990FEF0" modified="2023-09-13" version="1">MSKYDAPQGPPPGYPQQPPQAHYDAGPVGDPRGANEGYYGGAPPQQYGQPGQYQQGPYGAPQGGPYQQQPMMYQQGPYPPQQGYYPQEQGRGGSGAGGCCAGIMAALACCCCLDVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTW6</accession>
    <name>A0A9Q8UTW6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase</fullName>
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    <gene>
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        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71988695"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08817"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE REDUCTASE"/>
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    </dbReference>
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        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
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        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
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    </dbReference>
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    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="28658" checksum="61CB1D8201EE0FE9" modified="2023-09-13" version="1">MTDTRLAGRIAIITGGSSGLGKATALRFARSGARVVVADLSSSGVEAEITSQHGKDSATFVKVDVTQESQIQNLVQEAVKFGGRVDILLNYAGVGIETKYEMGPQLHDTPVEEFDKTWAINVRGGWLCNKYVVQQMLKQEPQPPNARGERIKGWIVNVSSVYGLVGGHALPMYVPSKHAVVGMTKQMAAGYAAERIHVNCLCPGFTKTPLIQNITGDDEKNDAIVGMHPWGSLGEASDIADAALFLCSDEAAWITGHCLTVDGGFTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUF7</accession>
    <name>A0A9Q8UUF7_PASFU</name>
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        <submittedName>
            <fullName evidence="12">18S rRNA (Guanine(1575)-N(7))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO22886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767252.1">
        <property type="nucleotide sequence ID" value="XM_047911420.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71992150"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12272"/>
    <dbReference type="OMA" id="WIQEKKE"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
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    </dbReference>
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        <property type="entry name" value="Bud23-like"/>
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        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="10">
        <location>
            <begin position="52"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="11">
        <location>
            <begin position="207"/>
            <end position="265"/>
        </location>
    </feature>
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        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="29465" checksum="5431E93DCF76DABD" modified="2023-09-13" version="1">MSRPEDILPPDLFYDDSESRKYTTSSRIKNIQAEMTNRALELLDLPSPSLILDVGCGSGLSGEILTENDHTWVGMDISSSMLAQALERDTEGDMLLADIGQGVPFRAGSFDAAISISAIQWLCNAETSDVSPEGRLKRFFDGLYASLRRGGKAVCQFYPKNTQQRSLISQAAIKAGFGAGILEDDPETKNVKYYLVLSVGGGDVTGTVSGMNDVEVQDARRKDRKRGKEFEKKGSKAWIMRKKSQMEAKGKVVKSSSKYTGRKRNIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUP5</accession>
    <name>A0A9Q8UUP5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUP5"/>
    <dbReference type="GeneID" id="71992006"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
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    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="33165" checksum="E17CAE4BE10B8524" modified="2023-09-13" version="1">MMASTKKRKKSDPSEQTVDKKPRTEATTPNPACKLLELPRELRDEIYKMCLPDETDDYDMEVMSRRVDWMTMPALLQTCQQIRSEGLKIGLFLNNEGWSLKITDCNAASLLYWTELVATYFPEHTSPKKRYVPGELRLGEPYIWLWGDMDIENLRQWCCWVHEGRLQMIEEPHYGMSCGERSAITAAQKIAVQFMDKPWEDCVEILQIVLDMIYYSDCICCKGSYWMIKAALSLRTLSLPLNSNSFKSIVHTSAETVQDYFDVPRVLLGVIPQRCVLLQLASAGVALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVS4</accession>
    <name>A0A9Q8UVS4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768660.1">
        <property type="nucleotide sequence ID" value="XM_047912800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVS4"/>
    <dbReference type="GeneID" id="71993530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13652"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="18092" checksum="9937C2037E72246C" modified="2023-09-13" version="1">MTSNIPIDPAVSTALQIFDLPPELRLEIYAHFISSFDYTKATHPSEGSYYLPLLNTCQTFRNEALRLWLTHLRNLRDEAEVIYETADVVAAQYLADTANTFDMEVYLKLQNAIFTTQAQFYSLRNMFRADSGTALDHAVEAPHTADGIVELLEWLEVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWV3</accession>
    <name>A0A9Q8UWV3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769653.1">
        <property type="nucleotide sequence ID" value="XM_047913705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWV3"/>
    <dbReference type="GeneID" id="71994435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14557"/>
    <dbReference type="OrthoDB" id="10071171at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF3">
        <property type="entry name" value="GDSL FAMILY LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43189" checksum="ED2F9E452402DC9A" modified="2023-09-13" version="1">MPQLTEPANLPPQPFNQTDLVFFNTTLRQTFHITTPSTYLRLRLSNAFGGANLPITAATIAVPLASGIGNGNLTGSSLINTTTVQHLTFSGEAEISIPPGALAVSDPIYFPVHANQILSISLYLANGQSTQSITSHPGSRTSSYLSRGDWTASKNLTDSSTQEVFHWYFISALEAWSEPAVSSFVVVGDSITDGRSSYNNANGRWTDLLFNRLHYHSSSTNNPALGNIAVSNQAAGGNRVLADGAGPSALSRIERDVIAHPGVKYAMTLEGVNDIGTAMATMEAQRVVGDALIQAYKQMFTRMHTAGIAVFGGNPLREETRMRVNEWIRGSVGMAGGFDGLVDFDEVMKNPINSTEMNPLLNSGDCLHPNPEGYQVMADAFPVELFEKLEKGSEYICVVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXU2</accession>
    <name>A0A1P8YXU2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Exo-1,3-beta-glucanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00192</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">0WU</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="10"/>
    <dbReference type="EMBL" id="KX943163">
        <property type="protein sequence ID" value="AQA29334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755623.1">
        <property type="nucleotide sequence ID" value="XM_047899340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXU2"/>
    <dbReference type="GeneID" id="71980070"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00192"/>
    <dbReference type="OMA" id="EGICAMR"/>
    <dbReference type="OrthoDB" id="1293114at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF26">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573470" description="glucan 1,3-beta-glucosidase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQA29334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO11257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="33274" checksum="DDAF540ADFC3FFCB" modified="2017-04-12" version="1">MRTTYALAAALVAVPAVFAAEKGIMGFSLGTKKTDGTCKFQQDYEDDFKAMKSHSGATVVRGYAASDCNFAQHILPAAKAQGVKVILGVWPDTDESFKADKDALVKYVPQYKDQVYAVTVGSEALYRGNFTGEQLLDKINDVKEALGGDVKCGTADSWNRWKDGTGDAIIKGGVDIILSNGFSYWQGAAAGRDAIDVYFDDMQQALGHIQEVSGSLDKIEFWNGETGWPSDGGSDYEAAQAGTENAKKFYQEAFCGLLDWGVNAFYFELLDEPWKPKSIGDNGVAQVETHWGAMTAAREPKFNLKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4P5</accession>
    <name>A0A9Q8L4P5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_02172</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755188.1">
        <property type="nucleotide sequence ID" value="XM_047901320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4P5"/>
    <dbReference type="GeneID" id="71982050"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02172"/>
    <dbReference type="OrthoDB" id="1405469at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IKS protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000699">
        <property type="entry name" value="Probable serine/threonine-protein kinase iksA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF138">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE IKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="166"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="487"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO10822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="689" mass="76385" checksum="5CA1BDE6D158A4E0" modified="2023-09-13" version="1">MADQTPPLQRHMSLIPYSHDSREIVLRRGNAVVVYDQNSRQLQVRDTTDNPIELTECPYCHRSMRSREPSGEESEYGRAFGPERPFVAPDYFAMLASSRRPSPAGSGSSTPSRRVLSALRSGRSREVSGSADPPTGAEFVGSEPATAGGQGISASAFSPGYFEQFFKTERELGRGGNGVVLLVEHVIDDVSLGHFACKRIPVGDSKAYFEKVIIEVRLLQKIPHKNLVAYHWTWLEDHQPSTFGPSIPCLWILQDYCNGGDLHTYVLGPKTMSTEAERLKARLRRRSKGDASPPQDLRGPSKLAFDEIFSFFRDITSGLHHLHSKGYIHRDLKPSNCLLQRDGGRTRVLISDFGEVQAAGAMRGSSGATGTISYCAPEVLQRTSDGSLGNFTTKSDIFSLGMIVFFMCFGRLPYANADDINEENEDLDGLRAEIQRWAGFNDETRSRLDLPERLYKYLKRLLSVDPNERPSTDEILASIKGGAALGDPGSYFDDRHPRVSSVDSPAPATRIRQQSYIARPSLASPVRHRSSGDIRSRSPIKREQRDSRPTSPLDSPLTVGPKRLNLSPPSIEDAVSPQQSPRLMLPPPPVRPVTAKLRHILHDPRTVLILRASLFIAKILTLSIPCRPYAANQWLLYSLLCLAATDLGLLSFSLRQSSLLFACHIVMVWLASQSGRLCEATKAPVWQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4S1</accession>
    <name>A0A9Q8L4S1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO10850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="260" mass="29389" checksum="50B03634E2D2E606" modified="2023-09-13" version="1">MPGPPDEVEVDEPVNLPSDDYAVRKIRGIRVEPNDVEGLPPIKYEVEWQGCPEWDTSWEPIQHIIFNRQAIEEYHARADGPEVNIGRLFESELFDGAYQWCIDHDIRPRPGTEAEHPRYVELLRLRRNSALFGGATVMVSPQSVQKVGTEEPQRAQKSSRSDSPAWCVSAKNHMPRNIHYGTQPSKFTPLPNLDRFTSARDCVTHGTPASTRDCAGPWKKHVEDSERRAGWNKVLSKAAERGFARVSPVDAGTRTREGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5H7</accession>
    <name>A0A9Q8L5H7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02232</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755574.1">
        <property type="nucleotide sequence ID" value="XM_047901380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5H7"/>
    <dbReference type="GeneID" id="71982110"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02232"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="23474" checksum="5909E9E41FA9BAC0" modified="2023-09-13" version="1">MTPKCGVCNEQDSKYKCPICELRYCSIPCYKTHKATHVDEDTTKSAENDGKAAPLPLDRPGTTQRVPKVDFTGFEKNEDFQRLLSRFPNLKYQLQLAYGVTLEPGPDEEFTWGRRDWLDDERNAVRGGFRGRGRGRGRGARARGRGGRFIPELPHDDRQRGPWTQEKGDKQALNLVHRMRIGSEDELVEGMSEFIELCQIKFGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6B6</accession>
    <name>A0A9Q8L6B6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RidA family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755972.1">
        <property type="nucleotide sequence ID" value="XM_047899874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6B6"/>
    <dbReference type="GeneID" id="71980604"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00726"/>
    <dbReference type="OMA" id="NARVIHT"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15028" checksum="7500158CC5B624BD" modified="2023-09-13" version="1">MANQSTTINPENVPVSQPLFSQVNSIELQGPARLIAITGQLSINLDGTPKVQGFEAQVKLALQNLENCIKAASATKRDIFKVTHHVVDFDFEKQNPAQILIEWLGIEHRPASAMLPAYKLAAPGLLYEIETWLVVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6T5</accession>
    <name>A0A9Q8L6T5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755624.1">
        <property type="nucleotide sequence ID" value="XM_047899341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6T5"/>
    <dbReference type="GeneID" id="71980071"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00193"/>
    <dbReference type="OMA" id="QYDADFQ"/>
    <dbReference type="OrthoDB" id="3644357at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="348" mass="38853" checksum="1C06DA2448C1AAD0" modified="2023-09-13" version="1">MPERKAIPPHLQRKLNGSAASATSSAPPASPASANDEHALVLSIANIEERSPTPITTVSSVSAGLQNNFTPTEMIQHDLINRLRLQVEHLSVKCDALKEENAQLKQAVEELELHANGEPMGDHQPRNLVGYESSDDGNPQEAETKGNLSEEIGNQIAVILNRHEDRLASLEARFIEKMAPTQGTVDDTKIPMANGTFPGLLPGGDGSLAKNVSDLEQTVESGQHQVNVHHLALQDLQDWRNQIENQEFKASDKSTDAPALQYDADFQARSERRLEQEGRIDNAYTREELLQHYVELCQLITHYHDDGNFRGTEDELWALRERVVMNLATFDAREKALEEARKWMEYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6X4</accession>
    <name>A0A9Q8L6X4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01869</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756341.1">
        <property type="nucleotide sequence ID" value="XM_047901017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6X4"/>
    <dbReference type="GeneID" id="71981747"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01869"/>
    <dbReference type="OMA" id="NEMPSIC"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000065">
        <property type="entry name" value="[Pyruvate dehydrogenase (Acetyl-transferring)] kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="314"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="50778" checksum="EED12012A6083CF4" modified="2023-09-13" version="1">MSWKKSAQLMDTIKHYSNFPATGVSLRQMVQFGSNPSTGTLFRASQFLSEELPIRLAHRVQELGDLPDGLNEMESIKRVQDWYAESFEEITTLSKPSLTNEIRERLLKPAKANGRNSRILSETTHNPSIKPGQYKSDAKLTANGETDKENVNGNGNGARRAAARRYFSAADDGNDWPPELEDYNTRFAKTLEKIKRRHDSVVTTIAQGILEYKRKRQRMQIDNNIQAFLDRFYMSRIGIRMLIGQHIALTDQRTQSDPNYVGIICTKTNVKELAQEAIENARFVCEDHYGLFDAPKVRLVCPDDLNFMYVPGHLSHMLFETLKNSLRAVVETHGQDKEEFPVTQVIVSEGREDITIKISDEGGGIPRSSIPLVWTYMYTTVDQTPNLDPDFNKSDFKAPMAGFGYGLPISRLYARYFGGDLKLISMEGYGTDVYLHLNRLSSSSEPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L869</accession>
    <name>A0A9Q8L869_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear movement protein nudC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for nuclear movement. May interact between microtubules and nuclei and/or may be involved in the generation of force used to move nuclei during interphase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757018.1">
        <property type="nucleotide sequence ID" value="XM_047900818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L869"/>
    <dbReference type="GeneID" id="71981548"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01670"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000001">
        <property type="entry name" value="Nuclear migration protein nudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="6">
        <location>
            <begin position="79"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00059400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="27621" checksum="E5E116BE72FB3B3A" modified="2023-09-13" version="1" fragment="single">NADLLQHRRCRRAGIVPAKLNMTPHTPRRTSAPSSSTRLSLETSTAIPPKMADDRPASPTPEERKKLDEEAKKRENEEQSKLPYKWTQTIADVDLVSPVPGNLKGKDFDVKITKTTLKAGIKGQEPIIDGTLPHPIDLDESAWTLETSPSGKELNIHLQKVNTMEWWPHVITSAPKIDTSKIQPENSKLSDLEGETRTMVEKMMYDQQQKEMGKPTSDEQKKMDMLKKFQEQHPEMDFSNAKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8Y8</accession>
    <name>A0A9Q8L8Y8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spherulin-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01968</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the germin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756749.1">
        <property type="nucleotide sequence ID" value="XM_047901116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8Y8"/>
    <dbReference type="GeneID" id="71981846"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01968"/>
    <dbReference type="OMA" id="MAFIEPC"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040216902" evidence="6">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="7">
        <location>
            <begin position="100"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="29781" checksum="E4AF1B815E3C5994" modified="2023-09-13" version="1">MAPTLSKNLLASLCAASSVAAVPQGSSPSSTFIVPNITAPATATPPASSAAAAASVSRVALAQEVKAEISNVRAFNALLTVDGAGQQLLEGDALRKRVVFDFGARAAVAGTGGRNVQADGATFPILVNENLAVATFFLNPCGLNSPHTHPRGSEFVTVVQGSVQTGFMLENGFLASSAQGRQTTRVSATLGPFQGTVFPIGSIHYQFNDNCEPASFISSFNSADPGTSQIAQNFLFHDENIVNITLGEVQSIDGTNIEEFRSSILANLVLAVDECLARCNGNGGGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9F5</accession>
    <name>A0A9Q8L9F5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA-specific adenosine deaminase subunit TAD3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757648.1">
        <property type="nucleotide sequence ID" value="XM_047901836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9F5"/>
    <dbReference type="GeneID" id="71982566"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02688"/>
    <dbReference type="OMA" id="HEPCVAC"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="530" mass="59622" checksum="06D2F5024A19F8EB" modified="2023-09-13" version="1">MEAMRSFLNGLLMPLARVATFSQHASHFIFRNTKIFHRAIMAMAATRRDSLLDNDPEPKRRMVHLKTKEECRLGNETIQVWTVELPSKHAEGILRVIKENVEGQDTVDLQHLRRFAKPRYLPEHVLGKRDKVKELYAVSRAWENTPASVMQAAGSSVWEYSNPGKSRNTASRPSTLHLLVCPTKIIDLKTLHALLSEHTPFASNAESWAYPLEIKDITVPLLAPTSSEQADKWSLEYWPTFYRKTNPFGAHPASIQKAEDELQNPQDDNIGIDEALALAEKVGDDHRRRGIGTGAGCCIIERVEGQTQIIALAGDARYKPQANAVANEDTGCHGSPMGHAIMRAVGMVGRKRLRCASQPVTKAAAKAEGNFAKGGLEHDIEARDAFFCDQPLTSLENEHFVKDNMRPDGYLCLKLEIFLTHEPCIMCSMALVHSRVGRVIFKRRMPKTGGLTAEMVRNESGPVSLGYGMCWRKELNWQFMCWEYMPEEEEGTVMRQDLRNDSTEKYQEAEDSTDSESANVTLSSFARMHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9K4</accession>
    <name>A0A9Q8L9K4_PASFU</name>
    <protein>
        <submittedName>
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            <authorList>
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                <person name="Chen L.H."/>
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        </source>
    </evidence>
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</entry>
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            <dbReference type="EMBL" id="UJO13133.1"/>
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    </evidence>
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    </evidence>
    <sequence length="177" mass="17191" checksum="DA78BD119D2B6E6D" modified="2023-09-13" version="1">MSSTTAMAAGSYPGGAMVPYTATFVLDDSSTTAVAVVGQVLNNGATNFVGYNDGSAEYLLTASAANAQETTLADGNTYYVSSGSIPGGYLATDGSAMNGISTVSGSTVPAFTPITGSDAAPTTSRSQTTSRAAGASSSSASAASATSTSQASGRQLSMASAVALTLGFVALTVGYLA</sequence>
</entry>
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            <begin position="34"/>
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    </evidence>
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            <dbReference type="EMBL" id="UJO14487.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0008006" key="4">
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            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27032" checksum="18C099E9E2C4F90B" modified="2023-09-13" version="1">MMQGRSFSQLHPQHCYLEQHSRSKDKIILASENSHPVQPNSHTSSNQPISNMGSRIPPRPREDLSPEEQNTYDEFTQTAEQGFGKNKEKFTYKDERGAFVGPYALFTAAPKVGRLAMELVYSIGELPLPADVKETAILTCGGHFQAGYELYAHEAVATKSGVLSQQQVDAIKKDLKPGQLNENCSLAYDVAKRLCSRPGPLPQEMWDSSVKAFGREGTIALVHYIGFYAYLCIALNAVDVPVPE</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="OMA" id="DRWVMSI"/>
    <dbReference type="OrthoDB" id="5579281at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902657">
        <property type="term" value="P:protein localization to prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040345">
        <property type="entry name" value="Mug56/Spo71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039486">
        <property type="entry name" value="Mug56/Spo71_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057379">
        <property type="entry name" value="PH_SPO71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029217">
        <property type="entry name" value="Spo7_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28076:SF1">
        <property type="entry name" value="PROSPORE MEMBRANE ADAPTER PROTEIN SPO71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28076">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15404">
        <property type="entry name" value="PH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23207">
        <property type="entry name" value="PH_SPO71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15407">
        <property type="entry name" value="Spo7_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01316">
        <property type="entry name" value="Spo7_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="764"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="967" mass="109891" checksum="0C2D302AB673E5A3" modified="2023-09-13" version="1">MPRPTLPADSHTAKRLEHATAQHLHETTRRVFIGPVPEGWLHSHRKQWYRQYVGNSAERQPTFTAAHPVSNVGHDTEAQPTNEGSGSLEPAEDALPTSPTLSAGGAALREPEPATSITSLLHSRRGSQRVSSVSEAPRPQPTDGPNDEQPTDSAPPLQPILNTSSRASRVARVASKLPVPKVRFTEASRLQLRARAQRLAAKGNFRSSKVKNGEMMKVDKMLIRIDITQQSLREDYDEKISQGVETKSLDKWREFMVVCRRHTEDDAEAVLQFYQTRVIAVKEGQSVKKKPKRQILLSSKTSKVNLYSALDKTLCVWMTNGMRTTIYYLRAQSTAAAVEWYTFLRGLLGHKRAQTLQINVPDLSVSLRLDDPFRTLEESQTLVDAAEGDEEALAKAVQEEKGAADAIVSRCLEMLKQSPAWDDVLKSWAQTDRIGLAWKRYDRLEWVFGAVEQRMYGTIGMQKTHDLELRPKDHYPLSMRQRDGEVLQEPTPVEGYLIRLTSQKGKEIKLKRMMYKRLYFTTQSQYLVFVQPAKSTPPPYKAPSREDNRTVPSAKEILDEMPLVYEVDPYPLEGDHVAWLGTEGLDGAEELEARDKGAAAEAERNVNMMLASDGFVNLCNVKHVRDFHRSATPVDEHLEDGSDVDFHEEGNSNRTEDGNTQEVDEDRVLELVLNNGLVIRLQAYNKATRNEWRSRLKLLVAYWTERKRADMALYKTTREQNLQQLGIDERAEAVVGQFAYKWEVNQSYASPKLYNMCGISECRTIHHSGVLFRKPRKHTTFNRCHVVLSHGHLLIYQDTLRKRSGKKLVHIHHERIASISLEGCYLYSGLLTEGDLLYQNQTFDSNAPGHHALPRIYLEDSWTSTDEDAMTTFVIWHAKSKSWFKSSQNVDDVRVAERSSLESDSKREKGKTKLTRVSQLGATGRSVVFKARSRAERDHWVLAIQVEIERLAAQNEEVRIVDDEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC34</accession>
    <name>A0A9Q8LC34_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759010.1">
        <property type="nucleotide sequence ID" value="XM_047907770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC34"/>
    <dbReference type="GeneID" id="71988500"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08622"/>
    <dbReference type="OrthoDB" id="3944128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040346806" evidence="3">
        <location>
            <begin position="22"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="761" mass="78641" checksum="4E6642B6CE5B849E" modified="2023-09-13" version="1">MLSSHSCILLWGLALVGGCCAAGAPSPEQTAATSTTSSSILPNPTPTWTNSTHQAAGNFSLYDKLPSLWFETCANNNQNPPCTAYCRSNDTECLRAADVVVPACAGLWNTYNGHVFDWRISGGVAPSGWSTVLSTYGADAIPSTTTVNVYTSFSTANATLTRQHPTDARLPKVTITPVYAVGNPVPSVSVETASPYSGVVSYITAPQPSCRYAALKTTNDCGQCSIYGGTVELLFWPPTTSTTSAGAPVITKSTVWDGITLFSPTVYISLSTVYASNSCMQVGQNHTGTLLAMKPEDVSTQIHIGGKVAAYTYGRVDYADLVGLPPLDDYEAQPSCIMFGCSTIFPTYSPTLVVPMALRTLEADWSSCVAALEGLYDPPIALTEAAVAFSITAPSRPAHTEAYTSTTLMLPLASEHIPLAAPTPTPTTSQDHPNQIKASSIVQGLESLLNGGEIAVGTTKAAGVTSSGSLPISSTLEFAPLDSDQSASSTLLLSLSASQPDDGYTSKGSVPEHTTARSQDDSRSFLPGPHAPSALSSTHTTTSTHSIENDTPQPIAVSQDDQGNFIVNGKTFAPGLPVTLTRSGTTVAASMLTSSGRTFIALGTASTVPLGDIGAGSSYSLPPVVTATSSISHAVYTAAGITFEANEDGELVFSSKTVALGGSVTLGSGSSIRTIFVTNLGNQTAIVVGNTTTARLVVETSSSTSHISHDSVGPTSSRPANRSGIPQSTTATPPDSNAAILRTAGFANIFLAILSGIWLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC85</accession>
    <name>A0A9Q8LC85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759176.1">
        <property type="nucleotide sequence ID" value="XM_047907828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC85"/>
    <dbReference type="GeneID" id="71988558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08680"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053212">
        <property type="entry name" value="DHP_3-monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469">
        <property type="entry name" value="MONOOXYGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47469:SF2">
        <property type="entry name" value="OS06G0597600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="83" mass="8642" checksum="0AEA76C692C3DD70" modified="2023-09-13" version="1">MNAAEFSNGTHVNGNPNAKPDIVIIGGSLGGLFAGVALKSHGYNTTILERTPTFLLENQGAGIVAGRDAIDSFKKYQATSAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCH8</accession>
    <name>A0A9Q8LCH8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759243.1">
        <property type="nucleotide sequence ID" value="XM_047907467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCH8"/>
    <dbReference type="GeneID" id="71988197"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08319"/>
    <dbReference type="OMA" id="IGMRGAE"/>
    <dbReference type="OrthoDB" id="4156665at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="23535" checksum="BEF42B95897F36D5" modified="2023-09-13" version="1">MAPSTRGKEALEKKIATLQLRLAPLVPLPGGLPPHPDFPKTLMAFHLLTEDQLDSIAHYYHQSTPGPFTNNYPANMNWDKEFLARRESRTPTTPSARERRHSKQLSQEENIWLEDLMNTVEDLQAPTAKEGEGIANGSNPYAGLTEKERIRIKRRKVGKFIGLVGMETPVEEIAGRIQNSLDRAVERSREELRRNEEVMLRRRKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCI1</accession>
    <name>A0A9Q8LCI1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="164" mass="18598" checksum="D5FBE0266C7DE54D" modified="2023-09-13" version="1">MLSLVPPTPSIPIRHSLKKTFVSLKEQEQQEAVNLITAATNSFIDALNSHNFDPSSPPWTKHHTADYTHTGNRFPKRSLSEWLAWMQATADEFPEYAIQAVDVQVQCNCNTGKAHVFLNNQTWNAPRGTVRRGLAVTEWRRDGEGKWWVVKTRTLRGMGLEDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCT6</accession>
    <name>A0A9Q8LCT6_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">CLAFUR5_08393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907541.1"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TWO-COMPONENT SYSTEM RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
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        <location>
            <begin position="220"/>
            <end position="288"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="32187" checksum="35C38285A42FD999" modified="2023-09-13" version="1">MEVGKMFEADAQKADVNLYTRKKSTLDLITTQWVTLDAGRLMQVLINLITNGLKFTRKEDERTVTLTVGATRHRPTEDDLNVEFIATGIARDTLQLDSQWGSGADIFLHFSVTDTGCGFNDEQKGKIFERFLQASPKTHSKYGGSGLGLFISREMIELQGGEIGVRSNQLENNQLEKGATFAFYIAARVVQPPQAEVELTRRTTNPRRQNQNTTFSQIYTLLVVEDNVLNQKVFRMQLQKLGHEVHVVNHGAEALEFLEKTSCWAGNLNSAINLSAVLMNIEVSYGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD45</accession>
    <name>A0A9Q8LD45_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">CLAFUR5_08476</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD45"/>
    <dbReference type="GeneID" id="71988354"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08476"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14851" checksum="ECDE8B6497540997" modified="2023-09-13" version="1">MSRSITRDWYRSSPDLVRMSVSAKDNDMDVDYYCDVASQLRPYRPHTGRDGWTLRLPDFSEAPPSSLLKDFKNPIARQGEAGLTAEEHEFLEGVAYTKFRSSTIPTNILATFPALMGHATWQPKGQNIVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD57</accession>
    <name>A0A9Q8LD57_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907627.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71988357"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08479"/>
    <dbReference type="OrthoDB" id="3849084at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="69" mass="7600" checksum="F52A5865958586B1" modified="2023-09-13" version="1">MANFFTGAFKWETAASNPIVLAPFLLSLVVNGRARPGFIVSDVISIEDAPDAYSRFERHELVKAVIAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD76</accession>
    <name>A0A9Q8LD76_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Initiation-specific alpha-1,6-mannosyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759618.1">
        <property type="nucleotide sequence ID" value="XM_047907739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD76"/>
    <dbReference type="GeneID" id="71988469"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08591"/>
    <dbReference type="OMA" id="VTWDLFH"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.20:FF:000004">
        <property type="entry name" value="Glycosyltransferase family 32 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF8">
        <property type="entry name" value="TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="433" mass="49123" checksum="6CAC373FB0B1B31E" modified="2023-09-13" version="1">MGRTTSRGADEKLKLMSPSRKEGLQIGVPKQLQRVLLPACAALLFLFFVTAGNWSSATEGVKKVLHKRPAHFPRKIWQTWKVDPMRFEERDHNTAQTWIIKNPDYRYEVLTDQNDLAYVETHFGPEGLNRPDIVFMYRELTARIIKADLLRYMIMYVEGGIYTDIDVEALKPANHFIPQRWNEKDVDMVIGVEIDQPEFKDHPVLGSKSMSFCQWTFMTKPRLPVMLTLIENIMMWLRGVAMEQNKPISQIELDFDQVISGTGPSAFTKAILADMSKNTGRTVTWDEFHDLNESKLVGGVLVLTVEAFAAGQGHSDSGTHEGRQALVRHHYHASGWPTAHPRFNHPMFGEVERCNWVPDCVRAWDENTATWEHMTPEDKMQQLEVARTNAEAAQKQAEDAYREAEAKGEQAPPPPPPPGAPGAPPLAEFLNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDU7</accession>
    <name>A0A9Q8LDU7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759765.1">
        <property type="nucleotide sequence ID" value="XM_047907151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDU7"/>
    <dbReference type="GeneID" id="71987881"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08003"/>
    <dbReference type="OMA" id="ICADERQ"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="292" mass="33073" checksum="67EED337DD4BB234" modified="2023-09-13" version="1">MQTREDLLICAACGTQFDVPADPPLKACRICDDPRQFVPPTGQSWTSLAQMRGKYRNTFKQDDIEPPMTSICTEPKFAIGQRCILLKTSAGNVLWDCLACLDQETVDFIMSKGGLKAIVISHPHYYITHLDWVKTFDRPVYFAKDDEEWVNQPDPEGRRKLFTDVSKEIVNDVVAIKTGGHFPGSLCLLWDRKLFVADTLVTVPSALYHVDRPPGTTSYAFMWSMPNMIPLPPKEILKMWQALKPFHFESTHGAFVGTEVRDKNAKGRVLESMKIQARNEGWDDVAIVHESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDW7</accession>
    <name>A0A9Q8LDW7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RING finger protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760107.1">
        <property type="nucleotide sequence ID" value="XM_047903518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDW7"/>
    <dbReference type="GeneID" id="71984248"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04370"/>
    <dbReference type="OMA" id="HMSEVLC"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="490"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="732" mass="80686" checksum="7B87B50D74A24268" modified="2023-09-13" version="1">MASTTSTSNGRVSNTSNNTYVMSRSPVKNSRRRTGEPYLPKIITTVGQRPACLVNASVTYVGNDLIYAFGGFDQYTDEVYNHVLKLNLSARQWSLVDNYGDIPGVRMGHTSCLWQGDKLLVFGGENEHRKHLSDLVIFDIKTAHWTQPEISGPIPRGRARHSAVIHDDKLFICGGMSGCDNNVLDDICYLDLKTWTWSRTWRLVPRFDHSSWVWGGKIWISGGMGEEMERTSEIWWLDFRGTPAFEGGPTYGLIGSEDARPLGERYASYSYAAPSPPMGTGYAANTGSVQSNTATQIQRAPPVAPGAISSVKFISSPNLPMQNVGTHFHVFSSGCMLDFVTPATNMPLETSLSALDLDSLRWQKLADGKDLFSPTYRWHYCCLDADGTHAWLLGCPRELRAGGNGEAEEYLSDVLPIDLRKFGLLGNKMSQEARNEQRIPTSDSNPQSHLSAIGADLARTFNQPPESGSGTDFTITALKDDVYDMEPFSDDDPLSPGGSATGDGSNASQPIHVHRLILSARWPHFSRLYNAQMSEFHTRRMHIPEPYPAVKAFLYYLYTDSISSPPAESQELSGPTLEDVANMLVMSNIYDMPRLRHLCVNRLVRDLDVQHAALIFDRASTAQEDWLKRRAASFCMTHWGRIVRTDGFRRLKRSAMLELCEGVDAEGRVVGGDELEAVGGLGGARLGSGMGVLWGNGRKRNRLGSTSGTTVDGDGDDADADLDADDEGMELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDY0</accession>
    <name>A0A9Q8LDY0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760048.1">
        <property type="nucleotide sequence ID" value="XM_047904050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDY0"/>
    <dbReference type="GeneID" id="71984780"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04902"/>
    <dbReference type="OrthoDB" id="4114825at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF1">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="170"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="801"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="860" mass="95359" checksum="C8EEE667EBA16B6E" modified="2023-09-13" version="1">MGLNRTGCASLVKRFDGYSKSSRTWDGLRKDEELWFEDGDCSVHLYAPGASRRGASLRVSVTPLEKSENTYLLSRCLRTNETSAATANETNSDKTCDASGPRNQVSELLELYLAAPTELARSEAFLYHVGTRNYFAYLLDRPLVGETLGQALADLAHRIEAWSPASVGTTAFLEYCQEQGYLDFANSPDYALAGMHFAELARIKHVWIDAFAHCVGMRDQLDNSPEAPRLSKTSKALIDRASLEMDLQITRVNKAVGNFLEEELGPEFHGLSRPLRDHLDRFRSTLHSFYVNTIGYFPPDPGSPWNKQLWQSMHDDFRSVYEYLADTQSTNDPTSSRGVSGGVCTTQNISVFNQRHRYSPLPYPVPLLPKDGTRQSTMLPQKASRLRSFMLGRSDAASQPRLRSHVKQALATASNADNPNVMANRLVQEYIRFEGLRLEEKVSLSESRKVRWLLVYGVLQMLISITRAPPEVQDSETPLYPMCAMASGCVPWEQSIMPAVEDEQMVKRLSAEMAAIREALEEDRISIHPDCEAESAEDYFAMTGLNRSDSDKSLTQLPQRSSPQLSRTASIRSGVTSLHRSVVGSLQSRRNSVNVDGIVQARRNSFRRDSWLQAPKKMSSFCEILVEGYGNGADDSRRSETCFQGCVEYTELEAPIPEVDTLVPILEMHQLGLYDEAGPSPVSSTCSGLSSQFSDLSGSTTNLRECNSPATELSSPMTKKFDFSSDTSLFKFEFDFHQEEDDAEPDLELTPKPSTALPPPTYRAKHPIDGDHTGRVSVNAGCYTPTGAITPRGNKSARNMSSDSLLSLASSASSEYPEDSNQAAEIEEREARGRARVRISAFGIVDGRISLPQSPVGEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEU8</accession>
    <name>A0A9Q8LEU8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acetate--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760513.1">
        <property type="nucleotide sequence ID" value="XM_047903728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEU8"/>
    <dbReference type="GeneID" id="71984458"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04580"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="83"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="489"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="651" mass="71599" checksum="B37017B18CE44393" modified="2023-09-13" version="1">MGDAGSLALRHVDVLPVPLERFGKTSPAPRFNDIEAYRKLYKKSIESPDHFWAEQARSLRSFQDGDNAWFPEGRLNASFNCVDRHAKRKPDGIALIFEPDDPSGQNRYVTWEELQQEVSRLAWVLTRDFKVKKGDTVAIYMPMVPGAFVAVLACARVGAIHSVVFGGFSANALRDRILDADTRVILTANKALRGGKVIPLKNIVNEALSQCPDVEHCLVLQATDGPVKMVAGRDRDWETESKKWPAVFAPVSMAPEDPLFMLYTSGSTGKPKGLMHTTAGYLLGTALSTRCVFDIHADGGDVFFCGADIGWITGHSNSLYGPLMLGCTVVIYEGTPVHPTPSRYWDIIAKHRVTQLYSAPTYVKSEAIQEHLRVVGSVGEPLAANVWQWVHDVVGRGQVHVPALLNPTKGAELTTPGVEGVLTIKRPIPSMSRTVWQDHDRFMNVYYNPYPGYYFTGDGAFRDKDGYFWIQGRVDDVINVAAHRLSTAELEAALLEHKYMAEVAVVGVPDDLTGQAICAFVSLNRTLDAAEAVKMAKLQVSDSIGKFASPKHVIVVQDLPKNRAGKIMRRLLRKIWCGEEDQLGDISTLINPPAIPAIINAVKGVGASGEVQAVPETPDPIDEVEELPMGAPRRMTEVEQLQAVARRLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF82</accession>
    <name>A0A9Q8LF82_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing YSC84-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760485.1">
        <property type="nucleotide sequence ID" value="XM_047903909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF82"/>
    <dbReference type="GeneID" id="71984639"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04761"/>
    <dbReference type="OMA" id="PTATGDH"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="127"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="29438" checksum="01A33A47DE7B6B85" modified="2023-09-13" version="1">MSGLKARALELLSAAKSGDPIQSLKRSVDAQTLWPESLDREADNAASILRSFFVDGFIVPYRTASSCPQEIIKKSQGLAVFHVLRDDLRSPAASGSGVILARSPDGKWSDTAGILVDFDLPKTSELEVIDVVLVFRDKQSLEAISRDDCVLGKTLRFSPGPLPKSDAGAEGYSTDSFLAPVWIYAKSKGHSIDLKLDGLKIYQAQDENDRYYGVHGISAKEILSGQAKGPSGGASTLRTTITALDTQSGDYSGLPASGSCPGDKRVRKGNSTNVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFB4</accession>
    <name>A0A9Q8LFB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760742.1">
        <property type="nucleotide sequence ID" value="XM_047903123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFB4"/>
    <dbReference type="GeneID" id="71983853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03975"/>
    <dbReference type="OMA" id="AMHGIFF"/>
    <dbReference type="OrthoDB" id="5342184at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040:SF9">
        <property type="entry name" value="4-LIKE CELL SURFACE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="31547" checksum="78C002470806DB07" modified="2023-09-13" version="1">MELPQRPNNNRGRARKCLCIGLPMLVVALLLVIIVPTAVILKKDHDGSIGLPATVLLPLYLYPTDDAWEPLYKAIEKAPKLNFTVIVNPNNGPGGMTDLMHFKPALQKPAAFPNVQTIGYVPTENGTRATTAVQRDVLQYSVWSNMPLNCTLNGIFFDETPYVRGNQTEDYLTIINGWAKGANGIESPKTIIHKPAGIPDYGSPLDAVTVFEDPYSALGSFLNANAPASPARGLCSFMINSVPESASMTDLVKALSKRGKYLFATDLAETDGKSFGGRWEEFVDAMEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFY2</accession>
    <name>A0A9Q8LFY2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxin-14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761262.1">
        <property type="nucleotide sequence ID" value="XM_047903920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFY2"/>
    <dbReference type="GeneID" id="71984650"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04772"/>
    <dbReference type="OMA" id="CDGLIYS"/>
    <dbReference type="OrthoDB" id="441517at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="40281" checksum="4D1F597DC0269C3A" modified="2023-09-13" version="1">MSNGRPKPLIPEWQRTAQTKPAPTEDPVYSQPEESQGQQDTESELKEVSVAPTPTEDDVDGEAKTAEPAEDALKDAQPAEAAQVNSGNSFGVNDFEMFRQHEQQQIRPTTTAQASLPQQRPAAPPIITYPEFLVEAHKPPPLITPSRVLNFTYGAGAVAALLYGASKWILNPMQDGLSEASHDFFTHSQSKVDELNERLSKIVTKIPDTKKDGTASEIDADETDSETSDPTELYHRDMGTQTSPPPTRRSSLPGGTAQEKKDPVTYQVGALDIMKSHLDELAAGSEKTAEANKDRQETMNKLRHYLDGLTYGGGSYVWQSSEDAMALRNGNDGKNDEIEHFKKEIRAVKGLLLSAKRFPAASRPVAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI52</accession>
    <name>A0A9Q8LI52_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional nitrilase/nitrile hydratase NIT4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762213.1">
        <property type="nucleotide sequence ID" value="XM_047905611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI52"/>
    <dbReference type="GeneID" id="71986341"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06463"/>
    <dbReference type="OMA" id="HIAVWPG"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF12">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="400" mass="43108" checksum="350BC48B4A632B53" modified="2023-09-13" version="1">MPQKLRLAVSQSRTLSTLSETLADLESTTKRAASQNVDLVLFPEAYLGGYPRGCSFGASVGSRSDEGREQFFQYFKSCVDLGDTPQGAGDAWVERKLPVPKGEEYRGDGTREFLERVARETGVFIVTGLVEKSGGTLYCGVLYVCPRMGVLGKRRKVMPTGSERLVWGQGSPSTLKAVTTTIKGVKITMAAAICWENMMPLLRYAIYSQNVNLWLAPTADARDTWLPLMSTVGNEGRCFVLSAISCVKRKNLPGWVTGAPATTTTAPAANGMPESSLSPQRGRRRSTFKEERHELVLPAIGEGSDVSSAVATTSTAGVNGQSELSGDDYACRGGSCVCGPRGEMLAGPLWEVEDGGLLIQDCDFEDCERGRLDLDVAGSYSRNDAFHLTVDGLDLDVATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI60</accession>
    <name>A0A9Q8LI60_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_05775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762204.1">
        <property type="nucleotide sequence ID" value="XM_047904923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI60"/>
    <dbReference type="GeneID" id="71985653"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05775"/>
    <dbReference type="OMA" id="DIRRIIM"/>
    <dbReference type="OrthoDB" id="201398at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000399">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="141"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="21395" checksum="56A00C4587E0173F" modified="2023-09-13" version="1">MPAFKFQHTVDRLDKPSSYTIGKNKKQKNRRGNPNDEPAEDRDRSENQPDIEDKLKHATTLYVGNLSFYTTEEQIHTLFSSCGEIKRLVMGLDRFSKTPCGFCFVEYYTHEDALDCLKYVGGTKLDERIIRADLDEGFAEGRQYGRGRSGGQVRDEYREEYDPGRGGYGRAVQQGDRYYADEYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LII5</accession>
    <name>A0A9Q8LII5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762493.1">
        <property type="nucleotide sequence ID" value="XM_047905410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LII5"/>
    <dbReference type="GeneID" id="71986140"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06262"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF43">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="730" mass="78408" checksum="22A28786ADDD4893" modified="2023-09-13" version="1">MAPRSSARGRRRRSWQHCDLTTFYTTTAAGSSMATSASAEAKKPEDCVPIWQDGTHGRSMPAGTKLRAWPQSTSPSQYASHSVPRVLFALQVALLVIVLGLVAMMYKSFVLASAAALVDADVLNGQAAGSAMAGGSSSVPQYYQTTPEFLPGPTPTGEAAFLAQTNPAPFAGTSYIPNSPLETQVPIMGNTDNGNIFQMHGQLSHYFPNPDGFGVDEYSLPRNASIVQLNMLSRHGARYPTTGAGAQVLGQKITNFTKGVTGNLAEPFAAGPHNFTGALSFLNSWTYKLGAEILTPVGKQELFDSGTLHQIMYGHLYPNNGTKIYARTTTEDRMLKSAEYFMAGFFGLQWPQNASLIVAIENSTGIWNNTLAGYYNCNNSNTGVSRGGDNATAQWASIYLADAVKRLNADGPAFNWTATDAYNAQSLCAYETVALGYSAFCGLFTYAEWESYEYSVGISFAGNNMFQSPTGRAVGIGYVVEIMNRLQGHLIREPTAQINVTLDSNVATFPLNQTLNFDFSHDTNIASILTAFGLTQFAPVLPATAIQRNRSLIVSHMEPFGARLDMEIIETPQPLNGDRKSGNAYDAGGKTRYIHFILNQRTIPLGASFEQCGKRDDGWCELTTFLEVQSTKLQEAEYNYSCNGKYAPVPYGMITNGVPLSGNSTSSSPASATSPATVTGRVQCPAGTKDGALVCNGDDQFGRCNFGNVIFQKVASGTACRNGKIVATGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIP3</accession>
    <name>A0A9Q8LIP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Saccharolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06298</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762565.1">
        <property type="nucleotide sequence ID" value="XM_047905446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIP3"/>
    <dbReference type="GeneID" id="71986176"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06298"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="293"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="781" mass="88053" checksum="696BA8196B46F323" modified="2023-09-13" version="1">MVQKMARHGKESTGRSQILLARSRPTWQLFSACAFTVLVLCYFARSTRFGLNHGPDLPLRRLAIRELDNLPSGIRRPPQAPQLFNDSPETIEEKAKKSIASEKQIVDDIVKKTAVANATFENTIVPFTEQFDQADGLTSFWDVYLAVSNDTKLQEAVQAVLPNFTKASQETYLNEEFFKLVDTVFQKQKDDQTLNAESRKLLAGIRGDFIDSGVNLPAGKKRDRFRGEDQKLAKLANDFENAITADQTALWFTVEELNGINPVVLKDLEKGEGEHEGKLKVVVQSPEAGGCNMDCSNATTRQRLSIAGTKLAPSNVDRLKQIIVTRDDQARLLGYPNYATWAIKDNMAKTPKAVEDLLNKVQSRLSLAADQDAERLKAYKKKDTGKAEFLFPWDGSYYGKISTAKEFGTNPDFVKEFFPAVQTLRKVLDLYSKLFSLKFVRIQGKDGDALSPTGKAGDLLWHPDVELYAVWEGKGDDFVGYLYLDVFYREGKRGSAFMMPVVPGYETKDGKRHYPSAGLVTNSKKAGDDADIPSLMYRGDVENLLHEAGHCMHQLTSKTQYSRFHGPIGCPTDFLELPSQMMQNWAWVPAVLKYFSHHYTYLSKKYLDAWTKANKGKKQPPKTLPDSSTDSIRRSKTSYAAVGTLGQWGRAIYDQRIHRPGSPQDVKAIDVTKLWNTIRFNATRTDSPRVLGLDSGHGESTFSHLVGLYGAAYYSYLWSQVYAEDVFYTAFEKDPFSAETGYRWRKTVLEPGGTKDFFEILKEFLGREPNDEAFFRDIFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJA5</accession>
    <name>A0A9Q8LJA5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">37S ribosomal protein S35, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761999.1">
        <property type="nucleotide sequence ID" value="XM_047905337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJA5"/>
    <dbReference type="GeneID" id="71986067"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06189"/>
    <dbReference type="OrthoDB" id="10052321at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="48523" checksum="3F65F41080C67F54" modified="2023-09-13" version="1">MPPRIQPQRLQTPCTCQCFRTRPNTTPESLPNSSQVRHFASSESRQRRDRAASGFVNPAATRLRRNMQEWLNGPGKAFREPLQNSTNYMSAYDRQGNLLRGKRPRNPRDMQEDPSKPEEVIPEEEEAALQAKQRADNMEEYEIQEQFEKRAMARAKNAALESRGGIPPERLGDMRPYPLNHVFRSERVLSEELREAIYNQVVARGTDISTVSAMFSIDVRRVAAVVRLKSIEKQWVSEGKQLAKPYNDAVLSMLPQTPFRPDLPTEKIVPHETINDLPVHPKTRQQMFYPVSESRQFTREDAAKAFDEKLLPADKRIAHPDMIASEKDALAGMSREQRFAKVHERDAKAAQEKREAEQKRRRWEERTQRVVPGRRWDFKFQDISAEKTGKDGRARNAVGVRYGMPHEDRKSNAVKIPTSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2U4</accession>
    <name>A0A9Q8P2U4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755480.1">
        <property type="nucleotide sequence ID" value="XM_047901225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2U4"/>
    <dbReference type="GeneID" id="71981955"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02077"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040443344" evidence="1">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="15364" checksum="6B7BE575D5D9A3F7" modified="2023-09-13" version="1">MALQTLLFLVATLALVSGSQDLTNPAPTCTSTITHRPAGCCPPRAGHTALSYTDCHGCDLEVITRGPQCLCAPTPVKPMTTTTKPCTSVVTELTRPCGDCGMGSVDVTTALNCKGCALSTTTVAAGGVGICACPTAPGMRGVFVCKAEATLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3B2</accession>
    <name>A0A9Q8P3B2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_00239</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755975.1">
        <property type="nucleotide sequence ID" value="XM_047899387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3B2"/>
    <dbReference type="GeneID" id="71980117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00239"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="24446" checksum="A551F8ADD14CF226" modified="2023-09-13" version="1">MICRQCAQRLARRNTSHITCRAFSQTTSNRAQAVTAQTTTATNPRPNDRPAATSTSAAQPFSTPLTPAPENLDLPTNKDVDKSKKPLQIQSSVPAGTVLKGLNFMKNKQDPVALEDSEYPPWLWTVLNKSGAAESGSGLDAEGDLFSKSKKQRRIAAKALKKRQLLDPESLVEKVPIYEQSVDLPRDPRESLGAREQLTKAMRERRRSKIKEDNFLKEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3D9</accession>
    <name>A0A9Q8P3D9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756022.1">
        <property type="nucleotide sequence ID" value="XM_047900062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3D9"/>
    <dbReference type="GeneID" id="71980792"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00914"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="19724" checksum="AABD7E1AE9611F35" modified="2023-09-13" version="1">MAPYFYFLPTVTHSQDYLAEQHTMSNTNNYDQAAPSVLATMDDCIAMDPHHVLGVAENARPALIKAAFADLAAKYHPIHYVNPAHTHEILLDQSAALQAVDLNDLVYASDQGPTGYLFAGWATPSIEPVRRGYDQWQAIVTRWNEIQWAYWALSKERGEGKLNIPRRGALPISSSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3I2</accession>
    <name>A0A9Q8P3I2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756426.1">
        <property type="nucleotide sequence ID" value="XM_047899748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3I2"/>
    <dbReference type="GeneID" id="71980478"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00600"/>
    <dbReference type="OMA" id="LICNERN"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000021">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000005">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Replication factor C subunit 1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
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    </dbReference>
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        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="12">
        <location>
            <begin position="344"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="458"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1004"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1014"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1080"/>
            <end position="1090"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO12060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1090" mass="120015" checksum="1F29045FCA2B9423" modified="2023-09-13" version="1">MPSDIRSFFGGKPAGTPAEKKIKEQPSKKRGRAKKIVSDDEDDEPVPKKAAPKKSAAKKQDEPEAALEETTAGDYFGKGKPKRTEAVRPARAKEATTDATPKKSTKSAKTNGSKATPNGRGSARSAKTKKSYADLDADDFPDDDLEDNADDVFKSNAATGQRLGDDYEEGTDDEDDKPIVPKKREVGKQKKLKDHEQDDYDPDEDVDMKDTNPDDDFVVPDDDEEIVEDKPAKKTPAKASNKRKSTALDEDDEDDLEVEQAKPAKKRATPKKAPAAKKVKKETPQDSAELTAIFDNIPTIEPPPPPPKAGDEEGDGAKKKFQYGNHANSAVPAGAISDSDLPQGNPNCLAGLTFVFTGQLQRLGREQGQTLVKEYGGKITTAPSSKTSYVVLGEDAGPKKLETIKKNNLKVINEDGLFALIQQLPANGGSGAAAQKYAEKQAKEEENIRKAAEEIEKQERARMAAAKSKPQQAGSSHAKTQPKAESQKDKGKELASSVDSRLWTVRYAPQSVNQICGNKTQVEKLQRWLRAFPKNQSKGFKLPGPDGSGVHRAVMIHGPPGIGKTTAAHLVAKMEGYDVVESNASDTRSKKLVETGLKGVLSTTSLMGYFSHGADDVEASKKKLCLVMDEVDGMSAGDRGGVGALAAVCKKTQIPMILICNDRKLPKMKPFDFVTYDLPFRRPTTEQIRARIMTINYREGLKMPVNVINALIEGSGADIRQVVNMVSTAKLDSENMTFEESKDMSKAWEKHIVLKPWDMVGKILGGGLFNPSANSTLNQKSELYFNDHDFAPLMLQQNYLGTNPQRSNKYNSEPKKKNLAALDLVSKAADSISDGDLVDRMIHGSQQQWSLMPAHAIFSFVRPASFVYGSMAGHRTEFTAWMGNNSKQGKLMRFVKEIQGHMRLRTSADRHEIRQTYMPLLFDKLIKKLQEEGKESVPEIIELMDSYFLTKDDWDAILELGVGKSDMENIKIETQAKATFTRLYNQQSHPLPFMKASQVIAPKKAPAKEKPDLEEAFDESEDEAVDDADVKDEEEDVDLSKDRYVKQPKKKRATAAKAGGSKKKKAKDDDDDEEEEEKPKKGKGKGRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4C0</accession>
    <name>A0A9Q8P4C0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757027.1">
        <property type="nucleotide sequence ID" value="XM_047900159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4C0"/>
    <dbReference type="GeneID" id="71980889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01011"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14502" checksum="398E429362AD6F91" modified="2023-09-13" version="1">MAQGAAQSTEDAATLAAALRSHDDLHHAWEAYEARRKPRAAYIARNTRVLQEWLHLEDGPAREARDEMMGHDNESSPVFWGSAARKDWLFSHDASRLAQTPEAIPPLPPRPPKEASVYDRKRHSGRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4N5</accession>
    <name>A0A9Q8P4N5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADP-dependent mannitol dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.138</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-mannitol + NADP(+) = D-fructose + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16765"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16899"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.138"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:16766"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:16767"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.138" evidence="5"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757283.1">
        <property type="nucleotide sequence ID" value="XM_047899898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4N5"/>
    <dbReference type="GeneID" id="71980628"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00750"/>
    <dbReference type="OMA" id="GKAMTKY"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF103">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
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    </dbReference>
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        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="347" mass="37427" checksum="1FD9609B9C998D2A" modified="2023-09-13" version="1">MFARSALRLSQRAARPASFAPLAARATFTSSARTYDPEVPVVSYRSGERSEEQLRFEAAKKAGPVSPPGADVEKHAIPLKPEIHSKLTPTLQNFTLPGKVAVVTGGGRGLGFNMAQALAEVGVRGIAIMDVQQELGDKAARELGEQTGIDVRFYRIDVRDGQAMGQVIQDVVDHFGRLDVLINAAGIADSNIKAETYDHDKFRRLLDINITGTFIVAQAVAQQMMALGNGGSIINIASMSGTVVNYPQEQSCYNASKAAVVQLTKSLATEWARYGIRVNSISPGYMDTALNRVPALEAQKKIWVDHTPQKRLGAVDDLNNLAVYLASDGSAFMTGNDCLIDGGYTLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5D3</accession>
    <name>A0A9Q8P5D3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758180.1">
        <property type="nucleotide sequence ID" value="XM_047901854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5D3"/>
    <dbReference type="GeneID" id="71982584"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02706"/>
    <dbReference type="OrthoDB" id="3640036at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16860" checksum="1BF8E6F5A2E99600" modified="2023-09-13" version="1">MPAELQLKILSDAPAREIQRCRAISRHYRDLIDLEANRSLCSVPGLARSTARLQAFIERYCEYPMTKIDEYGHDHALLDAFLDYLMLHGVCDPTRDEMKALCQVSPFAQYFIARQNGSPSYSVMRTNDYLRLACNQLFLHCFIYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5U3</accession>
    <name>A0A9Q8P5U3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758632.1">
        <property type="nucleotide sequence ID" value="XM_047902904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5U3"/>
    <dbReference type="GeneID" id="71983634"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03756"/>
    <dbReference type="OrthoDB" id="5221199at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDH" evidence="1">
        <location>
            <begin position="192"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="351" mass="39277" checksum="20E6BC0ED2D65864" modified="2023-09-13" version="1">MKDSSIMYDTDNHVLCEYTARPGWFDLEDIDERGLPTRFIRHNAAGKWKFWTHGHDFTAGAMRSYVTSSGTCSLDLGVPTFARHENIMLREAYRGMPPRPDLPIERLWERYQHLVLRQDRDDSAIKALLKNLSEEDFQINDSVDKFLMEKHTEMACDLKGKRDLLTGNVARLVTVEHDDIVAALVRGKSYAKTIVMGHPNPDADSIVSAVSEAARRTLLDPDQPCMPYAESMPPEVAHILGSELADIVVASAFNADNEVVLVDCQSSPDLRRNLVKAVVNHHPVTTEFPYYVARSSEVSWSTTLQVYFKYLGSGFDLGPLAAKVLAEATIVEAEPELMETMSTTDNLAMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P749</accession>
    <name>A0A9Q8P749_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759893.1">
        <property type="nucleotide sequence ID" value="XM_047907273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P749"/>
    <dbReference type="GeneID" id="71988003"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08125"/>
    <dbReference type="OrthoDB" id="4509278at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="266" mass="28704" checksum="EDB09244A9232AAF" modified="2023-09-13" version="1">MAERMSALSCLRSRSTVALKRRPNSPIAIARLDVGAQMLSLIDLKSRTVCQRVVFGGCTCGKITDFVPANSIVSENSIMCKAGLPNQFKDSVSRTRNFSQEWMTVKIRPPPEAVQYLLAMVHIRGVAAQSVSNHLISTYQQRKSSYHNTTHQTNTKMYTSAIILSTLFASALAAPTEKRQAGITIDFIGGPASYSLTIPQDGSWVPTNSDLNISKLRSSANILQICQFQTNPPPAQAAAAVYVPSDDGAIDVGPPQPIVAVSCSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P777</accession>
    <name>A0A9Q8P777_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760175.1">
        <property type="nucleotide sequence ID" value="XM_047903379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P777"/>
    <dbReference type="GeneID" id="71984109"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04231"/>
    <dbReference type="OrthoDB" id="5220117at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="30639" checksum="0570D54839C763FF" modified="2023-09-13" version="1">MEQDDWQTEHFNHRRIGHGHKGKGSAKGAVFDPRRCYGVYQLQCPALAKLQPTAGSAVKSVPTLEIHGPVEGHDDALMCSLEMPGLLSGVAILAGSRKVLSSVVQDLEHPEPEEEEDEEEEEEEEEDEAAGGSENGGKGESSNEEEQIPKSSLELADEKERRRYAAFEKNSFRSPKFWMRWRAVRMISDNSNQDDQAADIEATRDQHPEPLPGHTSHPSVEVDGGYLVFSGNDCASFSGTISCRSFDWKNVKLSGTKVVSKARECPRGWGDIVVEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7A1</accession>
    <name>A0A9Q8P7A1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="20562" checksum="48BC003A141F8559" modified="2023-09-13" version="1">MKRRSLLAIGGLISAATAQYVPPLTPGFKRRPPKPPPSYMVDNTDNTFGVAPDKGDMKAPAAHSAYFEALNTIVSDALGQVNVATELRQAGLRDDPDFWPNIVKHGQSPFVDNASQYTIFRNVKDYGARGDGVTDDTQAINDAIVNGARCGEGCGQSSALGAVIYFPPGEYQVLSPLVQYYYTQFVGDANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P868</accession>
    <name>A0A9Q8P868_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type transporter cicA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761210.1">
        <property type="nucleotide sequence ID" value="XM_047903723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P868"/>
    <dbReference type="GeneID" id="71984453"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04575"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="89"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="402"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="661" mass="73703" checksum="D06F0D4A3CE28D8D" modified="2023-09-13" version="1">MDESGLRLQSWILHRAYARQCRVPRNDDRCEQLCAKEPDGNEQKDSVEPKPVLPVTALMQQEQRNTGSVPWTVYAQFIKASGLLWNLPIVVGVLTLAQGANILTSLWLSWWTSTRFSGLQTPEYIVIYAALGVFQAILMFSFATTLTTLTSIASKNMLNRAVSHTLGAPVSFFDTTPTGRLMNVFSKDVDTMDSRLQDDLRFLLFIVATIVPVFALVISYYYYFAIALDPLGLAFVYAASYYRASAREIKRNEAVLRSHVFARFGEAIHGAMTIRAYSVEQSFRNAIATALDSSNGAYFLTFAGQRWLSVRLDTIGVLLIFTVGVLIVTSRFSVDPSIGGLVLSYMLSMVQLMQQLVHVFADVQNEMNSTERLHHYAHDLAQEESGHKLSPADPSWPTKGAVEFNNVHMRYRTGLPLVLKGLSFSIAAGEKIGIVGRTGAGKSSIITSLFRLAEVAEGQICIDGVNIASLPLHDLRSRLSIIPQDPVLFKGTIRTNLDPFGEYEDLRLWESLRQTGLVDYKTKDPEGRSSTERITLDSPVEDDGQNFSLGQRQLLALARALICNSAITFFDEATSSVDFETDKKVQRVILEVSKDRTLLCIAHRLHTIIGYDRVLVMDSGTVAEFDSPINIFDKGGMFKMMCEGRNISRKELLSQRKLALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8A4</accession>
    <name>A0A9Q8P8A4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761153.1">
        <property type="nucleotide sequence ID" value="XM_047904469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8A4"/>
    <dbReference type="GeneID" id="71985199"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05321"/>
    <dbReference type="OMA" id="SIMMARM"/>
    <dbReference type="OrthoDB" id="10461602at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="30676" checksum="44827E1B5CECD6E9" modified="2023-09-13" version="1">MFAFTSLLDKTVLVTASILLLALIHYKTTLSRQAMAGNSSSKSYHDRIRLSVMAQMNAIYNGNTTASHPASSSSTSPTSTSPSSPATTMLPIADINSPHPDNRVNLARVMYRMSDLISHLHNHYQATMPQKDEEEADPGLQWTSRTTTEFRLWIGKARRAAQQALVIRARTQVAVQLPGFVAKKSRVLGEFPSHLEEYFGLFCSDIATSVGVKYSVVHELGFAVQLRQNFGMGGSWGEDEDDEMALSAGGNASKYAIMQMFAFPNAYWALCLAGLIEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8P7</accession>
    <name>A0A9Q8P8P7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coenzyme Q-binding protein coq10, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04889</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761482.1">
        <property type="nucleotide sequence ID" value="XM_047904037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8P7"/>
    <dbReference type="GeneID" id="71984767"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04889"/>
    <dbReference type="OMA" id="QLHAAMM"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="5">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="30185" checksum="62EEAEF1B2467533" modified="2023-09-13" version="1">MKSIKPISSISSGLLPSALRQPTTCRAAFLANTSTRSTNHDRQAQHRTFVSNPFTQNQILTASRTLPYPSSLIYSIISDVSSYNQFVPYCQRSEVTKWSEPASDGKRYPEVAQLVIGFNDSISESFTSRLYCVPERIIEAVSGSSTGTLEKSPDAKHHSPRPSSDQDASRQNTVMSHLLTRWSLRPYPYKPPPTGAVHKEGVHKNHEETSPIPGQERTEVNLVVEYKFANPVYDALASTAANKVAEKMIEAFESRVRMVMEGPGTVKPNKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8P8</accession>
    <name>A0A9Q8P8P8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino-acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06032</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761810.1">
        <property type="nucleotide sequence ID" value="XM_047905180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8P8"/>
    <dbReference type="GeneID" id="71985910"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06032"/>
    <dbReference type="OMA" id="AMFSTAN"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF3">
        <property type="entry name" value="AMINO-ACID PERMEASE PB1C11.02-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="296"/>
        </location>
    </feature>
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            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
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            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
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        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="50"/>
            <end position="502"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="568" mass="62291" checksum="19B3E52B60CD9C42" modified="2023-09-13" version="1">MDAHDVEASKGRNWDKSGTDVDYIPTHDNELPPEAPMSQQLARELTARQVQMIAIGGTIGTGLFLGTGNSLAKGGPASMLIAYSIVGAIVFITMLSLGEMAAFIPVGGTFCTFAGRFVDDAFGFALTWNYSFNDAVSTAADLMALQLLLQYWTTTDNFPGWALSLIFLFILLALNIVSVRAYGEMEYWLSLLKVITIIIFIILGIAVNCGGNTTGEYIGTRYWYQGDAPFVNGIGGFASVFVTASFAYGGTESIAITAGETKDPQSTLPKVVRNVFWRVLIFYILSVLIIGLNVPYDYPSLATKDARTSPFTIVFQMAGSKAAGSFINAVVMTSVISAGNHALFAGSRLMYSLAVNRHAPQFLGQLNRHQVPWIAVLATAAIGGLCFGASHIGAGQLWSWLQNIVGVSNQLSWIAIGFASLRFRTGIRKQGLEHLLPFKNWTYPYGPVASVVLNSVLVLVQGWSCFSPRFKAVDFVSFYVELPIMLIMFLGWKLLKKTHFVRLEEMDFVTDRYDQGYTLEERDEMLRKAKLSPWAKGQGWKERGKRSACGSSSDQSCIRTMSPLLLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8V4</accession>
    <name>A0A9Q8P8V4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-mRNA-splicing factor CWC24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CWC24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762006.1">
        <property type="nucleotide sequence ID" value="XM_047905331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8V4"/>
    <dbReference type="GeneID" id="71986061"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06183"/>
    <dbReference type="OMA" id="ANFRKKP"/>
    <dbReference type="OrthoDB" id="25761at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034247">
        <property type="term" value="P:snoRNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="4 5 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="234"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="313" mass="34658" checksum="3E188E57552BBB24" modified="2023-09-13" version="1">MADVAAPVFKKRANKGSNIRKRPATPPPEESGSDSDYTDDEAGVRIKRRKKEGVTVGTGPKRQANFNKNTNFEADRSKTIADNEDATKASNWYTDAALAAKDAPSTTVSKTETVVPGATDGKYQGTAKYSTFIQKHPDHEKKVGPVKAPTNVRAITVTDFAPDVCKDYKQTGFCGFGDSCKFLHAREDYKQGWQLDKEWEKVGSKKDKPGQNGKEDTSDMTEEEKMLMEIPFACIICKESYKNPVVTKCGHYFCEKCAMGRYMKEKRKTCANCGADTGGSFGIAKKLKGLLEKKKKREEERAEKEANEGDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8W8</accession>
    <name>A0A9Q8P8W8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762005.1">
        <property type="nucleotide sequence ID" value="XM_047905329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8W8"/>
    <dbReference type="GeneID" id="71986059"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06181"/>
    <dbReference type="OrthoDB" id="3649752at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="16477" checksum="EBACBE16443F687F" modified="2023-09-13" version="1">MSPSNYNQSSLPPMAYDDPDWLEEVLATEARLEEEAGLGTNHSAILDSAPADPGLVPAAQLSDSTAATSAIIVLCPDIASIPPGRQPTANLMCGFPGCASVNLFSRKAELQRHMETHLPARFPCHVAGCDRVGANGFKRREHLRNHLRKIHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P937</accession>
    <name>A0A9Q8P937_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin spn3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762246.1">
        <property type="nucleotide sequence ID" value="XM_047905739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P937"/>
    <dbReference type="GeneID" id="71986469"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06591"/>
    <dbReference type="OMA" id="GYDSAMN"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000328">
        <property type="entry name" value="Septin spn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="17"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="392" mass="44594" checksum="959A2C1FDA4EB45E" modified="2023-09-13" version="1">MSSSPAIKLRRKKNVKKGIQFCLMVCGASGTGRTTFVNTLCGRQVLTPLDTDDPTTAHLEEGVKIKPVTVELELDEEGTRVSLTIVDTPGFGDSIDNEASFGEISSYLERQYDDILAEESRIKRNPRFRDNRVHVLLYFVQPTGHGLRELDIELMRRLSPRVNVIPVIGKADSLTPLELAESKKLIMEDIEHYRIPVYNFPYDIEEDDEDTVEENAELRGLMPFAIVGSDDILELDGKRVRARQYPWGVVEVENPRHSDFLAIRSALLHSHLADLKEITHDFLYENYRTEKLSKSVAGVNDSTGMVNPENDSLDPQSLASQSVRLKEEQLRREEEKLREIEVKVQREINEKRQELLARESQLKELESRMVREQTPSQPALTEDDESVAGATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P964</accession>
    <name>A0A9Q8P964_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase aba4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762336.1">
        <property type="nucleotide sequence ID" value="XM_047905230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P964"/>
    <dbReference type="GeneID" id="71985960"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06082"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF45">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="19961" checksum="C9DCBC700C451211" modified="2023-09-13" version="1">MRVCQIVSTIKQFGQLDGAAKIAGVYDYPTSELWHEQRGIEKWDHVIGVNLTGAANCLHVELEHMASAAASTGRKASQVKIAYYREHRYIASKHGNIGLTKALAKEYGPVGININAVAPGAIDTPMNANVGREVGDKLVAAIPIPRRGTAEETAKLIVFLLSEDASYITGATYTVDGGMTQYDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9R4</accession>
    <name>A0A9Q8P9R4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BCS1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762799.1">
        <property type="nucleotide sequence ID" value="XM_047906007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9R4"/>
    <dbReference type="GeneID" id="71986737"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06859"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="3">
        <location>
            <begin position="65"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18056" checksum="328F6B5DF7B1C5E7" modified="2023-09-13" version="1">MDFRRLAKVAETTGNSTDPSALTQLPSNILEALIPGYGPISRYILSTLGIDISIFVSIALILVIGTRGGQYLFERGESLFRKLVLSSAYIDDDDDLFDMVMEWLAEEQSSASRRSVRAKTQRGSKTDGVLEDGAGDALDATSFAAPQQSPHPSDFLSSTPPILLIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Z0</accession>
    <name>A0A9Q8P9Z0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="6">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07354</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 8">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762964.1">
        <property type="nucleotide sequence ID" value="XM_047906502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Z0"/>
    <dbReference type="GeneID" id="71987232"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07354"/>
    <dbReference type="OMA" id="VIICITE"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="9">
        <location>
            <begin position="51"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6 7">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="64"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="36238" checksum="6D70E04DEB0FE1AB" modified="2023-09-13" version="1">MQSMRQPLTRALRNAPAGLTKSVAPATYATISPSDAPGQPSGYAKTGLNLRVTKDTKVIFQGFTGKQGTFHASQAIEYGTNVVGGTNPKKAGSEHLGKPVFANVSDAVKEVKADASVIFVPPPLAAAGIEEALTAEIPLAVCITEGIPQHDMVRITDMLKTQDKTRLVGPNCPGIIAPGQCKMGIMPGFIHKRGRIGIVSRSGTLTYEAVNQTTQAGLGQSLVIGIGGDPFSGTNFIDCLRVFLADEDTDGIIMIGEIGGTAEEDAADFLKEYNVGGKDGKGKPVVSFIAGISAPPGRRMGHAGAIVSGGKGDANSKISALEAAGVTVEKSPASLGKTLREQFIQRDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAA5</accession>
    <name>A0A9Q8PAA5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763150.1">
        <property type="nucleotide sequence ID" value="XM_047906117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAA5"/>
    <dbReference type="GeneID" id="71986847"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06969"/>
    <dbReference type="OMA" id="EDTFAPM"/>
    <dbReference type="OrthoDB" id="3650560at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="227" mass="24879" checksum="BC3D7E7E00FDA615" modified="2023-09-13" version="1">MAPKKANWDVQRDHMLFMLLVDNINVNWNDVAKKWAEKYPNDECTPTGSAISQHISKLKKGSGPKSGLGAASKGTPIKTTPSAKRAAPPKTPSSSAKRARTTRMSDEDDSDEEKNMSFDTVGKRETPSRRSSGPRKSYREESDEEEDIQEARDEATTRRAAAAPPQVVQASDNLEAAPAPRDSVQADDYDDLFGGPRKATARSKSNPPKFDQIPAEDSDEDTFAPMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAZ1</accession>
    <name>A0A9Q8PAZ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apolipoprotein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07244</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763476.1">
        <property type="nucleotide sequence ID" value="XM_047906392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAZ1"/>
    <dbReference type="GeneID" id="71987122"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07244"/>
    <dbReference type="OMA" id="WAIVQTQ"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19438">
        <property type="entry name" value="lipocalin_Blc-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047202">
        <property type="entry name" value="Lipocalin_Blc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040557081" evidence="2">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="53"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="23323" checksum="188FF28A611BEF59" modified="2023-09-13" version="1">MLTTAILFLASSAGLASADFLNKRQSTNGTTQAAVVDATYDGQCFYPKPTDNFDLTSYLGRWYQVAGTIAPFTANCKCIRADYALNDNGTVNVQNACEAQGQVVNIEGTATPVSQYAGYGHVGVLRVQFPGQPAPDCPGPNYIVQDIGSGSANDDCHDIDAARDDSFAIVQASNFSTLFVLSRMQAPGNASIEAWLKRAERLGSDLSNVVVTDQSGCQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB06</accession>
    <name>A0A9Q8PB06_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763493.1">
        <property type="nucleotide sequence ID" value="XM_047906175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB06"/>
    <dbReference type="GeneID" id="71986905"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07027"/>
    <dbReference type="OMA" id="DYKDWTE"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="5">
        <location>
            <begin position="260"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="412" mass="46097" checksum="9EBCB3C97DCA8E72" modified="2023-09-13" version="1">MSRLSIRAYLSAARRHLQKCLIEKSHTSFVIGNESADLDSITCALIYGYLLSERPEVKRSGSLVIPVTNIPAADLQLRPELTALLKHADIKPSELITLDDIGTDSLSADKTSWTLVDHNSLQGKLGELYRSRVIGVVDHHDDEHTVSEDAQPRIITKTGSCQSLVINHLRDTWQKISDSAMTVGAAHPQNNETLVDDHAYTSTWDAQAAKIALGAILIDTVDLKAEHKVTEHDKKAFRFLEAKINISRKYGKDYDRDRFFTEIDDAKSNLDGLSLEDILRKDYKQWTEGDLTLGISSCVQPISYLTEKGKEFQGSLKAFAKSKSLDLFVIMPAFKEGGNFQREILLMTLSEKGNAAAERFAKSGQEELELEDKESSALGKDDEIKSRYFWNQKNLDASRKRVGPLLREAMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBZ8</accession>
    <name>A0A9Q8PBZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764035.1">
        <property type="nucleotide sequence ID" value="XM_047909628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBZ8"/>
    <dbReference type="GeneID" id="71990358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10480"/>
    <dbReference type="OMA" id="IRMDFEA"/>
    <dbReference type="OrthoDB" id="5546837at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460:SF1">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="23746" checksum="0E7EEBBFFC9A82BA" modified="2023-09-13" version="1">MAMNFAPYQSSPPESERAKSPPPARSPTASPKPQHSRQNSRNIASIADQSDPWAAARNQRLPNPSAYEDLDGEGPQPYNTRYNDYIGSAALEGGGATTSNYRQGISVFETSLGLPLNIEAALAYLVLPPAGGVVLLLFEHKSDYVRFHAWQSALLFSGMFLVHVIFSWTRVISYMLLVGDLVLIAWLAYGAFKNADTLDRVEVPVLGRLASSFVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCM9</accession>
    <name>A0A9Q8PCM9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 regulator dap1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764362.1">
        <property type="nucleotide sequence ID" value="XM_047909314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCM9"/>
    <dbReference type="GeneID" id="71990044"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10166"/>
    <dbReference type="OMA" id="ANEWETQ"/>
    <dbReference type="OrthoDB" id="547796at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="61"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="19039" checksum="A494B4468963D193" modified="2023-09-13" version="1">MDESSTMSSAEGPAAGVASIASPINLILFSLFLIIAYYRLRPTKTAPTLPAAPPPTVFKVFTPPQLLPYDGNQGMPVYLAVRGKIFDVTLGRNFYGPGGPYQNFAGRDASRGLACGSFDPEMLTEDLNGPLDKLEDLGGEEMEALRGWEERFNEKYLVVGKLVPVGHAEAEPDEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD46</accession>
    <name>A0A9Q8PD46_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764629.1">
        <property type="nucleotide sequence ID" value="XM_047909726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD46"/>
    <dbReference type="GeneID" id="71990456"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10578"/>
    <dbReference type="OMA" id="YPRKDGR"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF71">
        <property type="entry name" value="CARBOXYPEPTIDASE TRE2, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="325"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="513"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="777"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="910" mass="101427" checksum="B8FFD1D7ADE6900D" modified="2023-09-13" version="1">MEEDDKYKQYAHIAIPTYDEATSSRPSSLQNFRGPGEVSDDAERQGLLPQESTYRPPTVESPRSSDDSDLRLPEVTGDGDGDRRRVEELDYLDPSAPDPSQRQSLYHRARLRSKWTQHITNIGATLSAIRLPSFRSLYTPVSGGETTSTEPPPSLPSRFSQLPSIPDRYRMSAGTIARLCGLLFIAMVIYGLFILDVFPGNGRGFMGTRFDPESVRKYVQEHVDAARIEEYLTHISGYDHVAGTAGDLYMAEWMRERWINEGNLDDVALASYYAYLNYPTQDGREVSIVAPEEQKWTARLEEDILDMNKVQTLAWHGLSKSGEVEGHLIYANGGSKEDFAWLVENGVNLNGSIALMRYYSTQNDLSQKVQAAQHVGCVGALVYSDPKLDGAVLGAVWPDGPWRPESSLQRGSVAMSDRILGDPLTPGFASTQDAKREKIDGNPALSQIPSLPLAWRDAKVLLEHLEGKGKQVPKDWVGGDQGFVKNWSAGDSEGLRVHLKNLNDESEKQQIWNVHGLIEGLEQAEKKILVGSHRDAWCFGAVDPGSGSAVLMEVVQIFGQLRKLGWRPLRTIEFVSWDAKEYNMVGSTEYVEDSLDSLRDNGIAYLNVDAGLYGPDPVFRAAGSPVWKRAVLHVLDRVSTPGDNAATLKQIWDERKTKFGGLGTDGDYAPFQMIAGISSVDFGFEGARLKHGYPAHSCYETLDWVKQFSDPDFSWHRTLAQVWALLILEMADRPILPFDLKTYADAIKGSYISTLMTYASVQAEKVPGHSSLESNSFSLQPLRDAADELTRVAEEFHRFEDIWTANVLGAGGLESASFAKRRMAFNQKLSNFDRNLLDLPESPIDPYVHGLPGREQFKHVIFGPHDFESGRMSYFPTVMDALQRGNFSLAQERVERVAGVIRRATDELKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDI4</accession>
    <name>A0A9Q8PDI4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764930.1">
        <property type="nucleotide sequence ID" value="XM_047910502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDI4"/>
    <dbReference type="GeneID" id="71991232"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11354"/>
    <dbReference type="OrthoDB" id="3643498at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="322" mass="36862" checksum="FA3FC3E57C7520CE" modified="2023-09-13" version="1">MGKRKQMDDGDTAMPDMRKAKKSTTRAPNATDLMSPIPIRVNRSVKTRTATMARNAVFDTTELLENILVHLPLRDLLLAQRVNHNFKNVIESSPAAQSLLHPTLEPSNKRWGFRYDDRREHEACYVSIEKRHVAGLRVLSLNQDLFIPLHEDHLITAGRYEGEEVVFRTKKMEQGLLHYMRGHKQSHEHMYITQPHCTQLRISYKIVIGAHATVKGRSIVVRMEGEPTVADIFETILGVPGKKTRHDSNVVVVEKRSIPWSWNTVKEDHPLDRRVSETIGQLEKEHKSAARVARFSIFLPRIITPTQEEIEEVESADSFTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDX9</accession>
    <name>A0A9Q8PDX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765040.1">
        <property type="nucleotide sequence ID" value="XM_047910813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDX9"/>
    <dbReference type="GeneID" id="71991543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11665"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040442067" evidence="1">
        <location>
            <begin position="19"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="331" mass="34304" checksum="9B031C3A253A735F" modified="2023-09-13" version="1">MKSSALFIMIATTALAVAGPVGLESGARMPYHSRWAKRDPVAEAHADADLYSGWQAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWPAKRDAVADKDAAHTDAGLYGGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE68</accession>
    <name>A0A9Q8PE68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765175.1">
        <property type="nucleotide sequence ID" value="XM_047910084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE68"/>
    <dbReference type="GeneID" id="71990814"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10936"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="150" mass="16662" checksum="0046BE72DA013D31" modified="2023-09-13" version="1">MATTTKKCHLLALPAELRNTIYDLAVTDHTVDIDKQKRAAPGLLLASRQTHAEANGAYRRNSNFTSKSPTLMRQFLERLESGKSRLISTATYDATRLNRIENGIEVFWAQEVIFRIARHLTEKNVVLARVDAIRVALSTAEGGVVSTAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK5</accession>
    <name>A0A9Q8PEK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="9">HIBADH</shortName>
            <ecNumber evidence="3 9">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_11198</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3 9"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765353.1">
        <property type="nucleotide sequence ID" value="XM_047910346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK5"/>
    <dbReference type="GeneID" id="71991076"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11198"/>
    <dbReference type="OMA" id="MGKKVWH"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000630">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="11">
        <location>
            <begin position="32"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="12">
        <location>
            <begin position="206"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="37052" checksum="D7FB238D620DEA70" modified="2023-09-13" version="1">MRTTAASVLRRAATGTTSRRTFTTQSRLQATYGFIGLGRMGYPMAKNLRTKIPESDKLYIHDVNPAILEQFAKEHKGVTIAKHVREVAENSDTVLTVLPEPHHVQNVFQQMLKPPTLLSDAPVTSERLFIDCSTIDPRSSKEVANATHSSGQGKFIDAPMSGGVVGASAGKLTFMIGAPQELVDRATEVLSMMGKRVVHLGPQTSGLKGKLANNYLLALNNIATCEAMNMGVKWGLDAKALADMINTATGKCWPSEVNNPVPGVIEGSPASKGYEGGFGTALMLKDLKLAMQAAMEAEIIPRLGTQAADLYKAVEGDESLKGKDFSVVYRYLGGQDTDKLEGIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFR3</accession>
    <name>A0A9Q8PFR3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908205.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PFR3"/>
    <dbReference type="GeneID" id="71988935"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09057"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF24">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="36808" checksum="6595E8162EFB1FB0" modified="2023-09-13" version="1">MQNYIEEVAPWFDAHTGKRYYSRIEIPSMLSCPSWRAAALAISAKNIELREKRTLTAGPDSLPLHLYQLAVRLAIESMSGRFERVGTLAGCVPLSVYEMMTVTYDDWLRHVQGCASIYTHNRWNGSTGGLISGCFWDYARIDIWAAFCAQSQTMLSPDTWFDDPEAMLRLSKVEEDTHSQIAIWLTARVVNLISNTAPPATDAQFNDLYGAMLSWESMGSIATRPIVVRDANVETDHAFLSILFSTHSSTIDIPCGIAPWSFCWKLRQVFARRKLLHALAAAGIIETNSHTACLANSLQPAFIAGRHMRTKSQKFGVLELLAMIEWKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFZ9</accession>
    <name>A0A9Q8PFZ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766073.1">
        <property type="nucleotide sequence ID" value="XM_047908761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFZ9"/>
    <dbReference type="GeneID" id="71989491"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09613"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="23977" checksum="9073171C6DBD5C1B" modified="2023-09-13" version="1">MSRSIRTQSSVASFRTAKSQLSSEKNDSASLVDLYAPVTRDFALQPLAIPARTSSLALRSSQVTSPQDEHEDTKTSRAELQPLIGCFDQVQDQRNMITVYLTWPAFPKGQARTAATEAARYAVVRELQMLLELEHPIGHLRLELVDPRRAYHEETVRLLIQLGFTGFVSRGSGSAREMWKAGRCPLFPDSMRVHALRIAPQTKAGKSESSAVAKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGI5</accession>
    <name>A0A9Q8PGI5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09472</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766565.1">
        <property type="nucleotide sequence ID" value="XM_047908620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGI5"/>
    <dbReference type="GeneID" id="71989350"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09472"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF98">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="57009" checksum="4A48EE7EACCA0010" modified="2023-09-13" version="1">MTYLHEGAELVAESGRTYLAVDSLGQDNVWIGAEKGKDDHVVILKSPGPDDAPGVWPKFQQEMTMHELFKDCPTIREQVDRIAPDDSGSPPILVLEMIATTVWMARKKRPFTRSEIFAIVRGLLESLRDVHAKGLVYSDIKMPNIMLGGFENNNPSDGSDLTVKLGDLGEVMYPSSGTAQPIAYRAPEVFFKGEIGPASDIWAVGLVLSHLLEAQTHFSETGLYNDLFHEDSTADQSAQVLRSAISNDYDLKNTECYQGCALPFSKGADHVNRWDGLRERLSPADVAFLEEIMKADPRERPTAASLLQHPWFKNNDAPSDYVSQVEASADDGMKDTESAQGVDGNLPQAPQHTLPNSHAPIEFQSINESMAGKEMVVGTEPSRPTQTIASDKEKAPQDAANSSYAPIEFQSIDESTIRTSVEANDSKPEAHPGSDAIPVAAPQLSPVRAFSPIIFQDIHTIGVPNDFSDEAVSRISNAQKRLSARGVNSVQLNNQPLVDSKHKRESIHFRPISVGSASGLGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGQ9</accession>
    <name>A0A9Q8PGQ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766468.1">
        <property type="nucleotide sequence ID" value="XM_047908371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGQ9"/>
    <dbReference type="GeneID" id="71989101"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09223"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27343" checksum="9E2AADF5063A2883" modified="2023-09-13" version="1">MIPKVPWLRVMVSCWYIECSSRFDLFEGYGKDLAAHTMVCSAPVYLEHNPAQANSYTTLTSMALTNNEWTVGLPADFAKNLFESGEHADMVIKTPTHDFKVHQACVSARSPELARRVASAPIQAIGDLRGPLLFIEDPELTNSHMSCEDTIQVVLRWSYGLSNPSLQLPHGHTADDIVENFMRILPVRNAAAMYGIDDFLHYASSIIKKRLESCQSIAHLVKNVCGTVETTFWSRRSRGDVGSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH55</accession>
    <name>A0A9Q8PH55_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase-like protein sdnR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766693.1">
        <property type="nucleotide sequence ID" value="XM_047908293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH55"/>
    <dbReference type="GeneID" id="71989023"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09145"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040279283" evidence="1">
        <location>
            <begin position="19"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="94"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="447"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="606" mass="66972" checksum="6E8EFBADEFCF0749" modified="2023-09-13" version="1">MMLLLTALGIVCLPFVSTKVTDQSLQICPIQAHQCPAPTALASENVFLDAIKQLEDAIRANLTESPYNGTTFSLGMFSTSDDGLVYEFHHTDPGVANSHKGTTKADADSIYRLASITKILTLYLWLIKDGDRRWNDPITDFIPQLAASDDTEQDYITPDWSEITINDMAMYLAGISRDYGLNDVALTDYVTSLMPKLTSKTSVNNPANGINISASDDPKCGYLTAKEVYQKCDPKQYLQGVKTLAASFPSGYTPLYSNQDYALIGLALENLTGATLDDLFNSSLVQPLGLRETTFKQPSKITKNSVIPNGDEQVSQWNNDFGPINAAAGAFSTTNDLAAIGKSILNSTLVPKATTRRWFSVTSHLESLDQSVGRGWEIYRQKVGGHTVDLFTKAGYWGDYTSVLFLIPSYNFGFSLLTASVNETGKVKDKLSNVLTNMFLPVLEECAKNQARRNFAGHYTSSTSNTTVRIEVDEWPALKVTEYIVNDIDFMATVFGQFDASNGVDMRLVPNHLYKGKNVGFTGVYQALAPPTPTAQFYGKCPSWLDVDDFTYASVPLGHMVFEVDDDGRAERLELKAVRERLDRTRENASKLCISQRVFMDQIAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJH1</accession>
    <name>A0A9Q8PJH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peroxisomal adenine nucleotide transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_12712</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767875.1">
        <property type="nucleotide sequence ID" value="XM_047911860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJH1"/>
    <dbReference type="GeneID" id="71992590"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12712"/>
    <dbReference type="OMA" id="PLEMINT"/>
    <dbReference type="OrthoDB" id="446044at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="120"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="213"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO23509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="38257" checksum="BD85E9A9B94A1B6F" modified="2023-09-13" version="1">MAPATSKEEMPAWGLALAGSAGALVANALVYPLDMVKTRLQTQVKRSEKDTHVDAEGYVHYDGTMHAIMHIIQEEGIAGLFQGITGNLIGVVSTNFAYFYWYGLVRETYHKRIAKNNAPASTAAELSMGAVAGALAQLFTIPIAVVTTRQQTQLKHERKGIFATAKEIIDSPEGAAGLWRGLAASMVLVVNPSITYGAYERLRTVMFPGKTRLALHESFILGALSKQIATLVTQPLIVAKVGLQSKPPPQRQGKPFKSFLEVMKYVVDREGFLGLYKGVGPQLLKGFLVQGILMMTKERVELAFVLLFRAVRKMRQEQLDKLAKMAAEKIDQAKEQAKQVVNETKKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJL6</accession>
    <name>A0A9Q8PJL6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768102.1">
        <property type="nucleotide sequence ID" value="XM_047912098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJL6"/>
    <dbReference type="GeneID" id="71992828"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12950"/>
    <dbReference type="OMA" id="HHLVRNF"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="668"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="705"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="726" mass="81155" checksum="4B42A97573B02E40" modified="2023-09-13" version="1">MPKALQKRGRRMKRKHEDDPEDPVEEGSSKRQKSAGPEDRQQKDFVSLDVHDEDMSAAYPPMERAFFGMLDEEEQEYFKSADAQLERNEFETSEDRANWLESVWREADGKELKIAQSQSCSRLMERLISISTGPQLKNLFQKFSGNFIHLMSHRFASHCCETLFTHAAPHVSDELRAGTLKAQKDGQDVNDVYVSMENLFLHTLAELEGNVGFLLTDRYASHALRILLLVLAGKQTSTESLKGLLQSKRKEGVTVSGGPKPNIRPEVKDRPVPKSFSIALEKLISDSMAGLDTDKLRALATHTNANPTLQLLLSLELTQFGKSRAKDERSIIKTLLPDEPFTADCGSAAFLSGMVYDPVGSHLVEKIIECAPAKVFKALYNSMFKERLASYARNEMGTYVDCRIIERLGYDDLMEAHEVLCPVIPSLLEKNWTSLTRTLIERCTIRDIDTQAIAAQIDQTYQGEKGFDVTRLLKLNARQDTDSNQPPRVNGNASTSNADSASYLARPTDPTKVHFNILAQAMLIVPGSLSSLVLDSLIDLEPSLLLTMANDHIVTRTLQQALTTKNSSMIARRKLIQQFYGSMGDMALDKAASHVVDCIWEGTHGLAFIRERIAEELAENEAQLRDSPYGRAVWKNWKMDMYKRRRSEWVRQSKIKASNDGFQDFDELDKTKDNGSKEKKTPLQLARERHAQNKAKKDPGGPGTGSRSSNRSAAGASRPAVATASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJZ4</accession>
    <name>A0A9Q8PJZ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768176.1">
        <property type="nucleotide sequence ID" value="XM_047912486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJZ4"/>
    <dbReference type="GeneID" id="71993216"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13338"/>
    <dbReference type="OrthoDB" id="3642816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF52">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="23991" checksum="E86A857729589DE4" modified="2023-09-13" version="1">MWRFSSSSCPTCILFEVPSNISIKRIAPSTWISLIMTLWGIATVGQGLIRNNAGLQAMRFLLGLFEAGFSPGCVYLISMYYKRYELQWRLSIFYTGSFIAGASSGLLAYAIAKMDGVGGYGDWRWIFIIEGLATTIVGIACKWFVPDWPETVTWLHREEKELLTARLAADVAEARMDRLDKRAVKRIFSDWKICLGMLMYLGVVDTDVCKPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJZ7</accession>
    <name>A0A9Q8PJZ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swiss Army Knife RNA repair protein HAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768145.1">
        <property type="nucleotide sequence ID" value="XM_047912463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJZ7"/>
    <dbReference type="GeneID" id="71993193"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13315"/>
    <dbReference type="OrthoDB" id="5596992at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="40"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="532" mass="59452" checksum="354089A43C7BE2E8" modified="2023-09-13" version="1">MSTHTITALKRWSCQDKNLPAVHQIKAIHVYDFDNTLFSSPLPNKQLWNTGTCGQLQAQEFLHNGGWWHNPNILAATGQGLEIEEKRAWEGCWNEKIAELVQLSMSEEHALTVLLTGRKEDGFSELIGRMIASKGLEFDMVCLKPSVSPSGEVFGSTMLFKQALLRDIAFTYHSADELRIYEDRVKHVKGFRDFFFDLNKALMDNGGPRQPFVAEVIQVSEQETNMDPVTEVAEVQKMINGSNQAIRDGKAPPGTRPYRIKRSVFYTGYLIGQDDIEKLRSLVKLPANCPEHEVRHLANNILITPRPAPRTILDKVGGIGAKMTWKVDGIAVNENRVWAARVAPTIPGAKYYTENPTPCVVLATRRQAKPIEASYIRNWQAVPQNQQYEFETTVGEKVLLRIEEEYPNEDDYEASFPNAKNARKHPREEDFPPLGSAPRSNGRPPPRTQQRGDQQRNDGSFTWKSRQNDGNNHNPPNRGGRGGGHQRGRGDGFRGGRGRGDRGGGGRGRGRGGYKSLDDNVGSGYGSGGMQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKK5</accession>
    <name>A0A9Q8PKK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768506.1">
        <property type="nucleotide sequence ID" value="XM_047912979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKK5"/>
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    <dbReference type="OrthoDB" id="3650304at2759"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="46"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="23242" checksum="D6217CED9419A82A" modified="2023-09-13" version="1">MSGVAFEHGPLPQNTIHVRLVQIIQYDNQGLHLSMTVWPAQDAPPYRAVSYTWGSPEEPLSQVRINGKLFAVRKNCHYTLWHVQLHYPKCYLWIDSICINQGDVSGKSAQTAKMWSIFNDAKEVLIRIGPHVDSSERLLQLDWMPESIRSLKHHLTVWVHDPPNSWAPDFLAGASCSTTQMVDLLKRYVTFSRRGYWKRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71993362"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13484"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="34714" checksum="7701B2091DB8E1CF" modified="2023-09-13" version="1">MVQHAPPSANNWPLHYWKLPHVELTHRIDLQNRLNVLHYFWPASATTPRLQYLSNRANRGLISYDSCTTIELHSFCVQRKLIAKDDLPTTPGFASTRPNLITLLETSDDAQTFPLLALPPELREKVYAHHILSLLPPLHPPHEAFLTQSMTMPPPPLIEVSRLLRKEALPIFYDLHRAKIGVIDPYGNVFSDKAYAITEPVDALIARAPDAVIGRYQSLELSGIVSMNGRSGGRCGVWFEVEMPRERRKGSVKMMGKFGGAAVMERFEGVVVRMEGRLQAVLDEMTEHGRGLESSDLELFRKCFAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL66</accession>
    <name>A0A9Q8PL66_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768864.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL66"/>
    <dbReference type="GeneID" id="71993701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13823"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="18547" checksum="373CAAA0B607CC43" modified="2023-09-13" version="1">MANEQTLSLQGEAQSKTSKCHLLALPVELRLCIYDHYFADCIPNSTNKDGSALLEVCRTIRIEATPECEKHMTTQLGILDRQFVASTEHYLNIRARWASGTHPIFLSGMILVRENLDRISRRKCALIKMQGDIRQVWEREKAEDAFSLMVLEEKGSERLPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLB4</accession>
    <name>A0A9Q8PLB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLB4"/>
    <dbReference type="GeneID" id="71993758"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13880"/>
    <dbReference type="OrthoDB" id="10682371at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="115"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="837" mass="91740" checksum="712A8D21FE08506A" modified="2023-09-13" version="1">MARKDSIASDPYAYAIAKALEYIDAHTNEFDTESSQKKALSTLITTQKLQYADKYSYGLYDVGQYKLWTSLKQAAERHKRSGLNIDITGSNGINEVFKRGSVYFEQNYLITIRSAPKPVGVPPPTTVAVEEVSGRRPSRLPVGQSTASKQESAPRAGRKRSTLRKPVDEDGDREAGGDSKDVLSTASTSNKRQKTTGKPGIETLDKTRHGPTGDYDEDIDTKQNFLTMDDQPKKQPSRPATAKPAADQPSQRTTRNGAQKNAKPAGALKTTSKQSGLRPESLVEIDSDVSDFSLDDDEIQAAQSSDPEIDDIDEVTGNVSDEGEVTEADDNASEGLLDDEEVESSFEVKKSKRNAAAKSATVEEKSAKINIATKPKKRTSPALSDDDDDFDDSVRSEQHSSKKIKSAANRAGTPGPPSRVNGQGTRIEGEEDDFFDEEYEQSDDGDDGSDEQPPPPCSEVDADEDEEEEGSEVDELTDADTSAGRADIEDGRPLLSDSRPDEHQIKPTSPAKRASPNASDVWTPSKRQKKEDHRPHEAALAAVAEQAKTPEHDDTMPPNAPTIQQSASANVMTLEKTGMSSTDLQEAFNNLSKMIDQTSQRFFENIGQTSGRLITIAPSPYPALEAVYRHVLSTEHDYMVVIEEFAFREKFEPSDLLRSMIASQLLTKIFSVDLPWQIAASAPSSTYIAAAVADPRGDNGRPVKRVLWLASQAQINDEHFVATTVEPKAQQLAAGILLTLGEHLHEYTDTSNSARDWHTDMYRQLADACREALIVKSQMVASKLEGDWLWDALDADGNTSYEPQTALMAFPGFSVDTRDGVREEWLIEEDLIGGKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLE4</accession>
    <name>A0A9Q8PLE4_PASFU</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_13952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768941.1">
        <property type="nucleotide sequence ID" value="XM_047913100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLE4"/>
    <dbReference type="GeneID" id="71993830"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13952"/>
    <dbReference type="OrthoDB" id="10541493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="23977" checksum="D10D3ECD36B41D72" modified="2023-09-13" version="1">MQTLLEALICAFLTIKVFRKKLPWNSPMDCLTDPSLAPMDKYFRRCLEAKRVKYEKVVHAAAFDQIKDEEFQNTTVMEAAEVLTTEFAFTVMDQITLFRKGRTPTDGWYRRFLDNLKDVFWNALIMRGQFEASMDNFIIQWRWPKEPFDIDTMTTPSGHYSNKGAPVQYTILPAIVRHDYGSKGPGITAFRAMVSLNSKDIVGISKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMV8</accession>
    <name>A0A9Q8PMV8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769729.1">
        <property type="nucleotide sequence ID" value="XM_047913651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMV8"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:serine-type carboxypeptidase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
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    </dbReference>
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            <begin position="22"/>
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            <dbReference type="RuleBase" id="RU361156"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="607" mass="66586" checksum="CE3DBEBB1C785C9F" modified="2023-09-13" version="1">MLMKAFLSGAALLASLAPVHASLSPKFHGASPKINKRQVTFPANVTDYKTITTPTGVKIRYKEPGKEGVCETTPGVDSYSGYIDIAPNVHMFFWFFESRRDPANDDFTLWLNGGPGSDSLIGLFEELGPCRINENLTTVLNPWSWNNVSNMLFLSQPIGTGLSYAKEQQGSLGNYTGQFLNSSQTNVNGTWPILDPVNVGEIDTTDLAAVGAWHVLQGFLSGIDKLEGNDMKAPKKFNLATESYGGHYGPAFFNYFYQENEKIKNGSSKGYAMDFNSLTLINAIISETIQAGYYPEFATKNTYNITSYNETVYNYAKFANNMIGGCQEMIQSCEAAAMELNGGSVRGRITDIASRSPAIAAICSEAQNMCRDNVEGMYYNYGNRGVYDIRHPRADPTPPSYYEDYLNQAHIQQAVGVSVNYTGSNSDIYYQFQDTGDFIYPNFLLDLQDIIASGVRVALAYGDADYICNWFGGQAVSLQVNHTHKAEFNAAGYEPFMYGGMEYGETRERGNFSFTRVYESGHEVPYYQPQAALAHFERVISGVDIPQGIEKVSASLVSNGTANATHTNAFVPLPPTESAGYASWSASIVASYDALDLLPPPTATPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMW9</accession>
    <name>A0A9Q8PMW9_PASFU</name>
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    </protein>
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    <organism evidence="2 3">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO25324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="18064" checksum="872BB9D25FFEA22F" modified="2023-09-13" version="1">MTGEAGIQESTSRQASRASSEHFLRDITHSITESINRRNWNSSVWDNMSPDFVAQYEESRWTSGVTLQEHLHNLYSVTNIFPDSKASIIDLDVMIDDSNSQAQVNFILEIKNTPVGGPHVQYLYVMEWKKYGDEWKCTRHRGMAGMAGPSMVGSTVSGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ81</accession>
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    <protein>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQ81"/>
    <dbReference type="GeneID" id="71987346"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07468"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="67" mass="7029" checksum="64F6835A5BFDEA61" modified="2023-09-13" version="1">MSTLIQRPIEPNYPIPDTGPSQPPPVYDPTLSSFGPDPLGPWGPLPGPTPGPQPDGPDFGPLPPVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQX7</accession>
    <name>A0A9Q8UQX7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pheromone B alpha 3 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906065.1"/>
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    <dbReference type="GeneID" id="71986795"/>
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    <dbReference type="OMA" id="IPPLIWH"/>
    <dbReference type="OrthoDB" id="2874149at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004932">
        <property type="term" value="F:mating-type factor pheromone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14966">
        <property type="entry name" value="7tmD_STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001499">
        <property type="entry name" value="GPCR_STE3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097:SF1">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02076">
        <property type="entry name" value="STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00899">
        <property type="entry name" value="GPCRSTE3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="486" mass="54403" checksum="3675DCD43FF3778D" modified="2023-09-13" version="1">METAHYVFMDKPYPASIIVACLGIIIGIINMPAVHQHWQHRNLPMTAMTAATVYANFYLALNAIIWSHDNFDHWYNGMGFCDVGVKLDLMLNVLFPAAMSCVLRHLANVMDTSRAAVMQTTAQKRRGYVIDSICCFAIPALQIPIHYVVQDRRITIVSTGGCVPTSDASWVSFVFIFLPPLLWIALAACYSILIAVRLVRYRRSFNAILANSRTTKSRFLRLYLLCAIVIAGLLPMWTFFVIKNSLPRITAYSWNETHHPTEYRWNSASFESGGGIVPAEKIVWLVGGFLMFCFFSFGKDAVRSYRTALLAMGFGRCFPALDPANTRKSSISAAISSIGSKAKMMMARKESDMSSITNTVSTTGTTTYDDSPKKMSFLESIKEERRETRRLRDMAPPMKKKKDGSRSFTQIFGRGKPSSSYSDDPFMLSNMNNHIQSSISAEPMSPTATKHFRSMSMGGQDVLVQKEFRQASETAETLPPKAYEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URL8</accession>
    <name>A0A9Q8URL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09943</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764310.1">
        <property type="nucleotide sequence ID" value="XM_047909091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URL8"/>
    <dbReference type="GeneID" id="71989821"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09943"/>
    <dbReference type="OMA" id="WVARATN"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="104"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="401"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="52048" checksum="B0FC36371639706D" modified="2023-09-13" version="1">MPSRWADTEEDAAEDARRKAEKEEKKRLKAEKQRKAEEAQVAQRAAAAQANGHAREDGDERPSKRRRISQEDRGNALQHAPALARKLLRFNAPTWQPCRSVERFDRLNHIEEGSYGYVSRASEEATGEIVAIKKLKLNPATDGGFSVTALREIQCLNAVKHRHIVELREVVAGQGDSRGDVYLVMELLEHDLKTLQEEMEEPFLPSEIKTLLLQLGSAVEFLHDHWILHRDLKTSNILMNNRGEIKLADFGMARFCGDPPPQNLTQLVVTLWYRSPELLLGATTYDAAIDMWSIGCIFGELLTKHPLLQGKNEVDQLSKTFELCGIPTEETWPGFKRLPNARSMRLPSNSKSATGSIIRSKFPTLTNGGASLMNSLLSLDPSKRPSAKEMLEHAYFREDPRPKPAAMFPTFPSKAGQEKRKRRASPNAPIRGAAPGLQVDVDFNSIFKGREEEEKGGGFQLKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URN8</accession>
    <name>A0A9Q8URN8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764370.1">
        <property type="nucleotide sequence ID" value="XM_047909747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URN8"/>
    <dbReference type="GeneID" id="71990477"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10599"/>
    <dbReference type="OrthoDB" id="4738875at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="23637" checksum="42BAC4BBC860F6CE" modified="2023-09-13" version="1">MPSPITILPCHLSDFPSLTHAMISAFSEDALFASAFPNPMTSSQREEHYQYRLRRLTKAAKNPKMHWFKAVDEGIGEVVGVCSWRAPKGEQQDAAKAGDLEQLADESEGELPRFVKKEVFGEYDEMMKVMKEELGLEARKDFWWRGVGSQLLKHGLSQVVDREGGGCYLEASPAGASLYRRYGFEDRGVAKMMGGDYNIIAMLRPVQRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USC7</accession>
    <name>A0A9Q8USC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765016.1">
        <property type="nucleotide sequence ID" value="XM_047910002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USC7"/>
    <dbReference type="GeneID" id="71990732"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10854"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15580" checksum="42D7679A6E9E12CA" modified="2023-09-13" version="1">MVHQLPSHRTRPLPARPEHGNHTQHVLCHEKRHAVTNFWLQHTILCPTSLNRPRLWWSVNAMLPHIHAGDPVDRVQLALAHTGIHGMGRYVLGWVDYAAVNDDGGRERLKRDSAYGWLSARRLAEWDEDKARRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USU3</accession>
    <name>A0A9Q8USU3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765524.1">
        <property type="nucleotide sequence ID" value="XM_047910576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USU3"/>
    <dbReference type="GeneID" id="71991306"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11428"/>
    <dbReference type="OMA" id="YFAEVWA"/>
    <dbReference type="OrthoDB" id="422736at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="517" mass="58234" checksum="34DA8534343EA926" modified="2023-09-13" version="1">MHSVKRLGFLAVVACCTLLGPLFFGYHFSTIRDSSWEYLDAVSSGHLTKSGEQTKHFHLVLPATGPNDQFCKLLLSAGITGYPEPIFVGWAGHGVYNGTESHLFKITETLAYLRSLPPSADDDLVLILDAYDIWLQLRPDVLIGRYFEVLRKNDKRVKAEGIYGKQHGGAVIKHSIVQGPDKIHWPQGDQDAATWAVPESPLPRNAFGPLTDTDMFTARPRWLNSGTIMGPVKDMRDYFSATVDMLSRKYDSTWQFRNSDQYYFAEVWAEQEVIRLQLRDGENFTAPIVSGGGSGIVPFIPEGRRTEFGVCLDYETEMFQTAAAFDRHVTWMRFNGSTQSVSGYPGDAEEIGLTLQQSTSTKRIDQWVLQNDTLRSDGPWSAADPKDLPGIDEGSSWEDVMLGVNVVTQIAFPLFHITGDKSLRDRWWPRMWFHPWSEQLLKAAKRKQANSEDPSTFLVQNGVRYKQARPDGKESYGGPGADEKGGAWIADGEYVPWRDMCTQFEDQIFLKHMEGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT09</accession>
    <name>A0A9Q8UT09_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11275</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765693.1">
        <property type="nucleotide sequence ID" value="XM_047910423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT09"/>
    <dbReference type="GeneID" id="71991153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11275"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="354"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="200"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="808"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="872"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="318"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="922"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="943" mass="103179" checksum="0975CABF808DCA2C" modified="2023-09-13" version="1">MATPAAARGRTAEVIDLVSSDSEDELEELPQPVARPGHRLQHRQDDEPQAAAPQAARDSPVIPHLGPDFFGDLEELHGFDLNAMPGAMPGLQFDNTPPHPASPQQGPGQWVHIDGEPVFIPDSPVPQAQPQRQEMVPPLDLDARVVTVDDCVTRVLEIFPDVRLDYVHELYGSLGTPGDYEALSGEARYEQIVEKLVTGNYPKQDKGKQSQKKRKREEEDSAAIDTKRWEGPDRVQLPPHLKGSMVAMIKADFPTIPNAQIQKLLGTHKHFYQTYVALANMRDTSDPAKVWRGRSTSRGATADTIGANSGSQVILEELAAARKKVASVRAERAAAESLKRAENENLQRAMEAGETAECQACFDDLPMNRQIHCNGNVAHFTCFDCAATYIKSEVGEGRCRVLCTAGCGAGFAHAQLHLLSDKSLLQRLEQLQQEKDIRDAGLDNLEECPFCEYKAILPPIEEDFEFRCANPECEKVSCRRCKAVSHIPLSCEEHARENAKDKNLSTRHKIEEAMTAALIRSCNKCKKQFIKEYGCNKMTCPSCANLQCYVCSESLKDYNHFDQGPAGPHRAGQAAGAKKKCPLYDNVEERHEREVKEAEDAARAAAKADNPDVTDDDVQIKVSDSVTKATQDRISRGAVPEGAGGAYPGLHYAGLPGIPRPALPLFAHRQLGNMMADFDEDGDDDEDGDDEADMFLGGFAPQAVRARRVGDAVRRAARARRADDAVERDAIRQRLREAAQGHPRHQIGPLPPRVAQQFQPQPGAGLGQFGHLRGVIPVFDPPAADNDGLFRDIDILGQFAQVLNRAEGGRHYPGQGGRAPQQAADGPGGDPGAGRPLGQLNDGRDAVPGVFGGNPFFGGANLGPFLDDPRWLNDDLGAAGNGHNPPQRAEAPPDNDDQQLQQPQQARERRRLVLHGMQGRHGGRDLAQDLARGDPRRRHEHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT77</accession>
    <name>A0A9Q8UT77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765929.1">
        <property type="nucleotide sequence ID" value="XM_047908896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT77"/>
    <dbReference type="GeneID" id="71989626"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09748"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="34707" checksum="E16BB32D52283D03" modified="2023-09-13" version="1">MVYILQLRQYVGTQFTFGRKSACKETDWWKISQYLEESNQKLVRQRIMSCGRQKHSQVLSKPRMAMTSSRFTFTMFSCPAGISPDVADHHTSTQARRPAELLYRQPARKSPQIPPRTIDPYTLDEVPQSLEYARLGVKYSPGRSDAEVQAASKSFAIFFRRLEGHVLDLGISQDECAKWNNELSTPDSPMPVPYAFTTISHERCGKTLIMHLGPFNEVHVRATFVNATGTNYWAIEVTVAERRPRLEGIRQELWKVLQGCVALAHDKGARVIRLDDFVRRTFKKLDRKLDSFQWYHVLDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT91</accession>
    <name>A0A9Q8UT91_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765933.1">
        <property type="nucleotide sequence ID" value="XM_047908888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT91"/>
    <dbReference type="GeneID" id="71989618"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09740"/>
    <dbReference type="OMA" id="QGFTMEK"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
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        </source>
    </evidence>
    <sequence length="909" mass="100209" checksum="1FDFAD07CB20F0C2" modified="2023-09-13" version="1">MPPARTQAEYEAQEQRNKLAISYQSLLSEFSSSDLHTVGNYTLGRLIGKGSFGKVYLASHKLTNGSKVVLKSAKKDDANLAREIHHHRQFLHPHIARLYEVIVTESLVWLVLEYCPGDELYNYLLNHGQMPPDQVQRIFTQLVGAVSYVHNKGCVHRDLKLENILLDKAQNVKLVDFGFTREYQGSTSYLQTWCGTIAYSAPEMLRGEKYAGEKVDVWSLGVILYALLCGELPFDEDDDGSTKAKILIEEVNFPDHVPDLARELIRKLLSKRPLLRPCLGDILKDPWLADHAPQQQEILKLQQPPPFTTQLEKDVLQRMKGAGVDIDMVIEHVLAQRCDSLAGWWALLLDKEQRKERRRERKRKEREAEAKSIRRLSAASGRLLAQSNLGEIHEGEEHVIGDFPRSRGRRMERANGHASTLQAPDLPRVTETKSPTPEGQPKSKPKTSETRHSASRSRSRPAPPPKDHGNQLTRPRTARTRTTSRGSQSMLRVVTNNPDLLSPSYVPPPQRKRAKFSSTPLRQQLEWVKHFFKEGPLKRSKSPDEGEDKKKGNANVKPLPNGKTGQEHGDLRDLQRRSIGPIAQARRPSNGHRPDLQTRQTLPARPRINTTSSTGSGASARGKRTSLSPHTLTPHSSYRRTSGLRGRKSTSSSVSSIRSTYQHQPSHQHTHSKASSTSSNSIASPSGLSSASGSRLGRSPHSSVKVLPSTPTTGTFPAGLRFQRRPPPADIGSLPGFGGEGKSAFGSLPPPSSPGMLVFARRKRSVFKGPMNSSPHGRGGNPSGSRSASVQGRPSAEMMPGLTEEDEEEDEEDMEEYEDIDQFGPELNLNTTDLPSDDGGLGVDTEPVSPLSPLPGHDDNPLAAAGECVIAGTAGVPLTAEALAKLDLEGEKEAEELEKEKENQKPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU49</accession>
    <name>A0A9Q8UU49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766874.1">
        <property type="nucleotide sequence ID" value="XM_047911621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU49"/>
    <dbReference type="GeneID" id="71992351"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12473"/>
    <dbReference type="OrthoDB" id="3655896at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="893" mass="98262" checksum="D738CF0083259811" modified="2023-09-13" version="1">MSATDQTTGASGGGDENREGGRKRRKGPHGNRVPSTGQQDDSAEEKCDNCNNAGPTRRAFDGPNGTKICTTCNSHNQASSASGPNALPRCDDCGRHGKTARSYKGPDDKRVCQTCFRKNMKAAVPNTVPNAVADTSLPTCDNCGKHGKTARDYKGPEGKRVCNSCFRNPGPKAVVDTSLPRCDGCGKHTKQGRAYIGPNPGERICRSCQIKIPIVADTSLPRCDNSVPDPYATLMLEKEKEVDETVTTQLYIEWLLQNDAEEGRATWEEIDEAAMKEIQRLLAADITILFGTSSPLYQAFLASLKTAQPASTFPTTVDHMATTLNGGIHGDPAVLSALDQTIWNGRFPTFTPSDGLLCGPNALALTLNSLRLRGVQNDPTTWGDTRPFTPDDIMRTLFQNYNSHDTADYGTPTAEYNAYLDEAFSFWQQRNELLTLRDLDALQLRAALTLLYRSGALPVHFQLGVVASAYLRTTEAGDIVPQSARAEVVGDWNGTDAVAWVHNNIAFGHGEYSHWEGFNEDGRSNTVAGWGFHTRDSGEYSRQICTNASYDHQTLEQRKQREEYNQYHREKRQKKKRQFMCLPFRSKNSMRCDGAPGASCKQCGDDGDCTWQPTGKEPILAKTLAQWTTDDIAEVELAKLCKADDIPDEDYILGTFTARESGGGNANDINTLSNVLAQNQHYYDILLGHPHYVNDAAGQRPGGPGTPLVGMRLPLIRHGGKMVPARLGNLQDPPLEIHFITSGLAGFAVDVERWPEFYNFVVERDQIYGTNIAETIYVVPVVEATVIDGVGNHSLDFPAFSPGWTFYRNKYVQKHNLGDVLRRNALVRGIATVTQVFNVNLAVPHPPGSAVTDNYIKGMKHSADWRGNAYDETTTPRASHVAARNVRRNVAFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUT3</accession>
    <name>A0A9Q8UUT3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767581.1">
        <property type="nucleotide sequence ID" value="XM_047911312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUT3"/>
    <dbReference type="GeneID" id="71992042"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12164"/>
    <dbReference type="OMA" id="CHARKYQ"/>
    <dbReference type="OrthoDB" id="3650820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="17221" checksum="556347FD9361C38D" modified="2023-09-13" version="1">MAPAKSSMAIKAEPARPASTSDDNVQGSSQPQDVNATLQKFAEGMQKQKEESRARRQQREREIDQFRKQRIDKVQKKMKECRQQHQEALRESRRPQVDRLGELLAEKRDIESKLQQCHARKYQAFESMVEQYQYAITGRLENELKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV84</accession>
    <name>A0A9Q8UV84_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768074.1">
        <property type="nucleotide sequence ID" value="XM_047912296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV84"/>
    <dbReference type="GeneID" id="71993026"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13148"/>
    <dbReference type="OrthoDB" id="3650777at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="29360" checksum="86CDFF1F33DCE7BA" modified="2023-09-13" version="1">MSPNTATNTEMSQPTTNNSQDRKPTGMLDLPPELRLLIYSHLLTSNKPIELWPTKRLLASTTTKPSTRTTTRIIRRPNPSNPKIHPEILLACRLINEEASSVLYGSNTFKSLGANIPRFITQIGSNTESLRHLELRDVQNWIEITQDFTALEHATGLTSLVIRYHPATWGTDGQILIRALMRLMRSWAQNRGATADAKCLENLVKIVEVLPKEQQVMLFGRSRRAGWKLETPNMERAKKVEEKVRKAILEELLKESASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWM0</accession>
    <name>A0A9Q8UWM0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769560.1">
        <property type="nucleotide sequence ID" value="XM_047913304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWM0"/>
    <dbReference type="GeneID" id="71994034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14156"/>
    <dbReference type="OrthoDB" id="3630793at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014988">
        <property type="entry name" value="Uncharacterised_YqcI/YcgG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40045">
        <property type="entry name" value="YCGG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40045:SF1">
        <property type="entry name" value="YQCI_YCGG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08892">
        <property type="entry name" value="YqcI_YcgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040108867" evidence="2">
        <location>
            <begin position="23"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="39150" checksum="60E1C0947FE47AA5" modified="2023-09-13" version="1">MQLAINVVIFFLGLYLPTLVASKPRKAREDLSRNVTRQIQKIISAICGRGQPEEGVDVEQEPESIEDGAARLYTKEQVESEFDMNAWQRLAYEDFKTTILAKETGLKTFPCVYATMGYRAGDHRYVFLESDDPSEPRNVRIVAPALRAYLRMSNTLGDNTSMVIMAAPTEGDPKSVEEYNHSFWEMLRGLRIWDSQPWPKQFPQDTGDEKWTYCFDGTPLFPVALTPAHQKRWSRHAPVPLIALQPKWVLDKLLSTPEKREAATGKVRRLLKQYDQTEISPDLTSYGDVGTSEVHQLCLRDENETADVPFQDFDKGGSSVAFSRRPSLESGRSSCESRRSNHVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXI2</accession>
    <name>A0A1P8YXI2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell wall protein phiA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Philalide A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PhiA-1</name>
        <name evidence="3" type="ORF">CLAFUR5_11110</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943043">
        <property type="protein sequence ID" value="AQA29214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXI2"/>
    <dbReference type="OrthoDB" id="4093325at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573419" evidence="1">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="195" mass="20766" checksum="9311E7ADC631249E" modified="2017-04-12" version="1">MHTSMLGLAALASTLVAASPMDPIDVVWKAPKVGDKFGIAATGEGIFNKGLTATMGGIFVGGKQSPSCDRGARQDFANFWLKEDTSISLYKTDNPPQDLWVDASDMGGGLVGYTTGVFEQLPKSAARTGFAVDPDTRVLTFNGVGGKACPTGEDQKWTLSFTDSERPRNQHGCVTVELKAFVRDTAVSCWYSDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4Z1</accession>
    <name>A0A9Q8L4Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LIM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755267.1">
        <property type="nucleotide sequence ID" value="XM_047899428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4Z1"/>
    <dbReference type="GeneID" id="71980158"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00280"/>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000077">
        <property type="entry name" value="LIM domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="621"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="782"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="570"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
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        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="843" mass="93652" checksum="67F900F4DAC2068F" modified="2023-09-13" version="1">MLKSKDRPTPRPTSMSEEQMAQYLADLRNARPPRPSGARPPPSSKYTTLKRAESDVVDTKPADDVSRPALPSSNSMPIIPAQSLSHRRTESSLSKRSMCSARGPFAGRPLVTPPEPGVPTSPEKPAIRHAPSMPYMEHGMRWMEKQEARSLREALQDMDLEEEKKIHSDAQDEAAELVWKHKYPGAAAAPTVFANPDLKDYRSHLRKGSYQRSHSQDTASAGHRTSSDGSQSSGTSINNSSKRVSTIDRPRKVSPPTGNMSVQKRRESAGKSYDHLAKAVEKDIAIAHRRSSSGSRRILSGEKKMYMHPNDKIWEDPQEDLSTPEKRKQEPVEDRRESVPTAAAVPSYVRKNPFARVRAQAEKLERSNSAPVISSLPPTPVLRHDRIEIQRNSPSQSRNPWYVSNEPLPPTPSSASARDADEVAPKTTPTREGKEIRGDDIRAATSKGRKDYSPNLPRPTMVSDKPGRPIVSFQKDYKPKEIVMEEQHAGPAPKQEPEPSKPSPYQIAKPAPPQVTVNHGPMPPVPTISVPDEPSVPSIVLPDDELHEDASSSRDVPEIQVEALTINVTVADSSTGSPTRSKIPQRPLPSARPLPRHAATTPLPATKSTPHYTPSMRQAGALCAHCALPIAGRILSAAGQRFHPGCFVCHECKTNLECVAFYPEPERKRDERLERIHIRRSGFNVPMPEDMSEEQFMRQEATDGDDTLRFYCHLDYHELFSPRCKSCKTPIEGEVIVACGAEWHAGHFFCAQCGDPFDSTMPFVEKDGYAWCVGCHTNRYSSKCRKCKKPVTDVVVKALGSDWHSNCFVCMECNGEFTDGRYFLRGNSQDPVCVSCEERRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5W2</accession>
    <name>A0A9Q8L5W2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-1,2-xylosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5W2"/>
    <dbReference type="GeneID" id="71980509"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00631"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF104">
        <property type="entry name" value="PROTEIN CAP1, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05595)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
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    </dbReference>
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        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="652"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="959" mass="106150" checksum="E57ABA4586BADC8C" modified="2023-09-13" version="1">MPFSSSQSRSQHDAASSSTVTLPLVLLIASLLAQIGTSPKHAILTSAVAWLAVCTYTTLKIGARSSLDGSSSQRLAWGAGVCLAVAGICERAVDGRAIWWAKVLIPLLIFLSTKAGILEHAQPASSSPPSSPTKPGSVRACHELVSKRTLAIITGSGLVAVYTHSGSISVIALGLSYAVVQALALHLVEGARYQSHDVGGVIYSANGLLTQPVMPLASAANQWMSLLRDVSASAGATLGVAALTLENLRFGGLAYWGLMGKIMGDHWVFGQSIISVVHALGTVMIQVVMFAALLLMVNDRGAFLTSFVPLAATLASQLLLAFSTSRLYFAALCIGGTFSLLNEQGTFLGGGRMRIRISKLLTVVAAVSFVVLTFYYLLQPIQNASLRAHGPQATVGLNVAPPVTLLEPLQSADTRTHPVRTLVQDAQRSWSSKLQSQSQSLEAAVTEYKRRYGLAPPPHFDKWYEFAKRKKVQLVDEYDTIYHSLLPFWGLAPATIRARAREALGFGDNNLMGLLVREGKAFHVEGGQEWLQQAAVGMMEQFIEYLPDMDLAFNVHDEPRVVVPHDQLCRLLQVALEKNVPAAIAQTTPKNTFSARPKDVKSGKRIEEVKTTRFNVFAHQPTWIPSRLSCSPDSPARMLEESLATDNLTAYSLSELGFIYNHTSFSDICNSPSFGQSHGFFDRPNAFNVVHDLFPIFSQSKMSSFQDIVYPSPWYWYGKVKYDESKDLDWEKKENKLWWRGSTTGGFSRAGGWRRQHRQKFVGKVNALDNAKVLRSSNAAATDEDPGSKWIVKDVPRQDYQEIMDVHFSHVGQCDPGDCDAQREFFKVVEPADQQEAWRYKYLLDMDGNAFSGRFYAFLMSHSLPFKMAVFREWHEEWLKPWVHYIPLSLRADEALEAVRYLDAEEDGKPLATTIAETGREWGHKALRNEDFEVWLFRLLLEYGRVIDDDRESIGYTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L730</accession>
    <name>A0A9Q8L730_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Inhibitor of growth protein 3</fullName>
        </submittedName>
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    <gene>
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            <authorList>
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                <person name="Chen L.H."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
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        <location>
            <begin position="281"/>
            <end position="372"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="94"/>
            <end position="150"/>
        </location>
    </feature>
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        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
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        <location>
            <begin position="732"/>
            <end position="846"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
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        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
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        <location>
            <begin position="779"/>
            <end position="826"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="846" mass="96394" checksum="0FC0DA881A67F879" modified="2023-09-13" version="1">MTQDEKPPNGTHKRLEEHNTNDLRDERSANEYSKQAERLGQLTSDQEDHSTGSTQAAEATFVTPFDPVIETADGSRLPAIPVDEAAELNRLEDLAEGSEPRSPPLSAVRSGKDGTVHGRFKAGPDNEGSVRQSDETDAPLRGAIPPSRTNPLFPPLPMYGPPSWMRTIQCWFFRATSAVLSFYFLLAIVIGAIVDSVPRIVRNCRQRAVLKNPAKSRPFYQEEVKRKEERRAAEKAWVREQKGKGTRTPSGEKGDETNDLPPQDGEFVPTEGGPDPLVVDVAYYARRVGLDAEVFEVQTEDGFIIELWHLFNPRDYKTPPPEHHQYQPPNLFRTTPENPEFGEAQPYPEGRKKYPVLMMHGLLQSAGAYCCNDDDSLAFYLAKSGFDVWLGNNRCGFEPKHTTLKYDDPRMWAWNIRQMGVMDLPALISRVLAETGFPKLALIAHSQGTTQTFVALAKEQRPDIGEKISVFCALAPAAYAGPLIGKIYFKVMQIVGPAMFRMIFGIHSFIPLMLMAHKILPPVPYSWMGYHVFSFLFSWSDSRWDRDLRNRMFQFAPTYVSSESMRWWLGRECFANQKCILATREEGKLEDKEDEEDDAVIQEYYAEREKRDKGITPRGRLTRNLTSFHCQTLTHQHHDNQRGKFAWYDKRFPPLALWVCGADDLVDGRRLLRRFDRGREPDVRVVHEKIIEGYEHLDVIWAMDAIEKVGKEVREVIWRTADPATQKKYRVPVGCDRPMEQEPSSNDVPMTRSGGRSRMASISEMQPSVRTGGGGTVVEESREPEREQEKLQRREDEVDEYRGDGAGDLDERRENESLFEDVRERANPTSPLELPMEGRMLGVVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L907"/>
    <dbReference type="GeneID" id="71981299"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01421"/>
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    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
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        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="29193" checksum="2489C4F4AE2DA43B" modified="2023-09-13" version="1">MLMWHSWPVSGLNRGSVARREIVHPHSPNKRAVLKGAQGIVAQSRPNNVVCTRTMPNTNTYTSYTTLKQATKTMAYWSRTTVKVQTLTMETTIIPDNASETITETSISSVQTTTTFIQTSTAVASTTTTNIIPGPTVFNACNDRNIFGSTLRSGGDRFYAVNIANNGPGVASDFTKIADGASTATECCNACQRLPTCETFIFRKQFRSCFLLSHEGATCSSQDQHPNFILSAPMTDDMDGSDGYQVGNDKCGYTWSGQANGKLRRVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9D9</accession>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71982269"/>
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    </dbReference>
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            <end position="216"/>
        </location>
    </feature>
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        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
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        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="27629" checksum="D853670F114FD09E" modified="2023-09-13" version="1">MSTNGVPAGTPTYTTAFVRNNSATRDFQHEGETAAALGLLQLYADPVIDPPAQQPRLSTTSRVATATCSLMVRLQIPGARLAAQVGSQEQGDSSNGADASTTAAPTSTSSLLAPPSTARRMANGISNFAKRATGRKRGSPSSTSPEPPRGTKRRASLDGGEPRTLRVDRFGADVASADPNLSPSAVPQADQAGQGPSDMGAGTASLRRGGNEGDEEMNDVELENENVVEGCEFDMRMTLCLLRGVMGVCCAAKIPNPVVWLSLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9E6</accession>
    <name>A0A9Q8L9E6_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_02392</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901540.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71982270"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02392"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="31366" checksum="15D36B32CA4F5B72" modified="2023-09-13" version="1">MSSSNRVKVTRQYAEANCTTRNFHHPGHGIYYEGLPPPGAPYSTGLIGPDAAAWKAESTKEKQQARFDAAEALVQLQQAPVVYAPSATSSEQPRRSLMLRIRTARSLMGRLRVPKTRLDGQTAEQEQVDASDDADGTAPAPQDPTSNSPAPAPPSRTQRFPNKVSDLAKRATGRKPDSTSSTSSPEPGRDTKRPAFTSPTGALPPLRYSDNGSPYLANKSRDKVKEDRETLPVDRSGGPMVWEVDGYPPGMTPAGASGQGGGGSSRGVVGQRRGEGESDEGMEDGESMRDSNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9W6</accession>
    <name>A0A9Q8L9W6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03741</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757846.1">
        <property type="nucleotide sequence ID" value="XM_047902889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9W6"/>
    <dbReference type="GeneID" id="71983619"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03741"/>
    <dbReference type="OrthoDB" id="4790878at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="28186" checksum="7BA3DC39C7F32098" modified="2023-09-13" version="1">MDKSPLRRLPGELRNRIYRLALIQHDPVKLDSTGMNKFIDSGSKRNVKNALDLPSTRKQVREEGLSIFFAENRFEIKTDILNGDEKHVAKAMFSTRIAIGGWLLSLGDSARHIGKVTVVLSGWVAWHHSEDWVEAAVVRVMTELRFLFSGTCAAPEVHLRCNWSHVKRRKKDFFVNPVLALTFRDHSTARQALSQAFDDEEGLVRRSTPKLGEGSYGLIDADERELQLQRTREMVGILTARMGRTFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA61</accession>
    <name>A0A9Q8LA61_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758005.1">
        <property type="nucleotide sequence ID" value="XM_047901797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA61"/>
    <dbReference type="GeneID" id="71982527"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02649"/>
    <dbReference type="OMA" id="KAHDYVQ"/>
    <dbReference type="OrthoDB" id="1044435at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="36554" checksum="014B643FBE01BEF0" modified="2023-09-13" version="1">MHWRMNQQEGVTEAQKMMHPRKQLSGDMSQVADALVPDLDGNGRAYNRRDYQELFSLPDASETSTGDSDESDESLPSVLHVEMPTKSPGMVPVAYSRALNNRIKEHMISEGGSYDILKYKPTFIHDVFMAPGSLSNLLGKSSPEDCIRKMTPGLLAGFHRHVQPTTLQPCVLKSSKAHDYVQGIVVFGLGRESRTQLHKHYKAFAKRKTVEVVVEIEIPSRQNAGTFEKKRRAVAAHAFLWRDKHEHFEPERVGDTWTLEDYLGQNLGPKQTGLRISPTMRGDEDDDGYTGRDIVEYEVEAEQREVVFGSAGSLSYDRADAFAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAM4</accession>
    <name>A0A9Q8LAM4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RuvB-like helicase</fullName>
            <ecNumber evidence="15">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_03479</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="15"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758352.1">
        <property type="nucleotide sequence ID" value="XM_047902627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAM4"/>
    <dbReference type="GeneID" id="71983357"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03479"/>
    <dbReference type="OMA" id="IINTEPY"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 15 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 15" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="68"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO13986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="472" mass="51594" checksum="4AC3C04AFCDBA12D" modified="2023-09-13" version="1">MAAPITTVSDSKERQGLNLIAAHSHIHGLGVTPDTLTPKPAADGLVGQLQARKAASVILQMVKEGKIAGRAVLISGPPSTGKTAIAIGMSKGLGEDVPFTMLASSEIFSLEMSKTEALEQAFRKSIGVRIREESEVIEGEVVEIQIDRSVTGNNKSGKLTLKTTDMETLYDMGTRMIDSMTKEKVMAGDIISIDKASGRITKLGRSYTRSRDYDSVGADAKFIQCPDGELQVRRETVHTVSLHEIDVINSRTQGFLALFSGDTGEIRSEVREQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDELAPIVIMASNRGSTTIRGTSYKSPHGLPLDFLDRVVIISTQPYQCDEIQQILSLRAQEEELDVSPDALALLTKIGLETGLRYASNLITTSHLLSQKRRAKEVEIGDVQRSFQLFYDPTRSVRFVSEFERRFIGEDGGVTLGAGTNGVTNGDAMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAX1</accession>
    <name>A0A9Q8LAX1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758443.1">
        <property type="nucleotide sequence ID" value="XM_047901669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAX1"/>
    <dbReference type="GeneID" id="71982399"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02521"/>
    <dbReference type="OMA" id="GWSCNVL"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="236" mass="26775" checksum="0BF4EAB81C445C12" modified="2023-09-13" version="1">MFRRLPHNLRRPRPEDIARVSDDGTSSAAAAAESNQPATFPRTPTDVLDTIRWLQRASQHRLPNELIKMILHNADYDCIHFLASHNTLVSRFSTGEETPLQPYLATTPLLYLPTQSSSEGGRIRRVTVRATGKDQGWCQNREGGFWSWYELGKNGVNGEQQRGPVWARNAMAKKEPQDHEMVYDAERPEDSSSEVKAWVEDLKNGDAVSIVPMARFKGWSCNVLKASIDVEVEVWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAZ1</accession>
    <name>A0A9Q8LAZ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758531.1">
        <property type="nucleotide sequence ID" value="XM_047901972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAZ1"/>
    <dbReference type="GeneID" id="71982702"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02824"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="23997" checksum="ACFB13ADE92B2B1B" modified="2023-09-13" version="1">MAQIHDLPSELLESILQYLPMRDVLLNQRVSIHWRDLIQTSPQLRRQTFLGFVPVKKVTNNNLSSFVCNHKSPAASFCGSSITSENPVSTTSSKASTSSLVHFNPVFPAEGDIIRMRTSQFRGKPESTKSWLDMYLTQPPCRLAEATVYYTKSRGLIAWGRRSSYTEVRAVQVVRSCGVRARDVLETVRRLSVGSTKKWQRIDIRVPGVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB45</accession>
    <name>A0A9Q8LB45_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758544.1">
        <property type="nucleotide sequence ID" value="XM_047901708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB45"/>
    <dbReference type="GeneID" id="71982438"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02560"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="261"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="630" mass="71003" checksum="9D389549E37C5B40" modified="2023-09-13" version="1">MVMELTFVNQYGDGAPKRRRLAKACESCRARKKRCIHFAGANNKSNEDHDEDDRDDTLPNDTSALANGISHSRSARSGVRRFISDMNPATTFLHRNNHHVGETGVEQNEDIGIWVDKREWDALIRQKKEANEEATKSAQLNNQRPHSAVLAPLIDIYFKKIHVIFPILNEEEFRRDHAGGLIPEPLAHAMCLVAAKDPEAAPHLRLSQSDVPLAPREFCGRLHASVMAAIRVPVRYEKIMLIRILALASLHAEGQDGAEEATMCANQAMHYTQTLGWHLGQQTDVASGDNLTTKRLFWCLWSLDRINSCIYGRPIMMSDIDIAIEPFEPGESGFPAFEVWLFITRLMNKIIHFYRPGNPPSVTGWEEEHYPSFEEAVDEGQAWDQPQSVLATLHLFYLSVAILSHRSRGVKYMPRSGPSYVRQNLCSIELHRLMKSQLFTLLHPLPILPYAISLALSVSYQHLRQAQLNHQQEDAREDFRTCCKVLQTLRRTWSSADVIATIAKKVLDEVNKVSDLSSFRVSRLSDRARNSPGICTASLARPDTIIDQREDQDTEAEGTDLADTAAVHDLNGVSTQYNPELFEGMDDLFGTYMDPNYPVNLDDFSFVDDLSPLDWNAMPTQGMTTGGQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBW9</accession>
    <name>A0A9Q8LBW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Allophanate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03372</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758920.1">
        <property type="nucleotide sequence ID" value="XM_047902520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBW9"/>
    <dbReference type="GeneID" id="71983250"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03372"/>
    <dbReference type="OMA" id="VTTECCF"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006043">
        <property type="entry name" value="PRK08186.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF169">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="268"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="708" mass="76607" checksum="FB38B62573CA8E60" modified="2023-09-13" version="1">MAQTMELPSARPYAYKFRPESTALIIIDMQRDFLDYNGFGQIQCGNNDLFQKVRDIVPRTQRALEAARALGLYVVHTREGHKPDLSDLPPSKRLRQISAPSGHHTMGIGDEGPMGRLLVRGEYGHDIIDELKPIPGEVVIDKPGKGSFWDTMLHRALLARGITHLLFAGVTTECCVNTTAREAADRGFECCVLADCTDGFWEPFYTSTLDMLCSYDGLFGFIGTSTELVNQVPPQVQTPPTTPPGFAGDISIRGLRRQYSTGQVKPTEVVKEVLMRVDAYQKKDPAVWTYLRSPQELIAEARAIEDRFAGRALPELYGVPFAVKDNIDVAGVQTKAACEASAYMPIENAKVVNVLTAAGAIFVGKTNLDQLATGLSGARSPYGTPRSAYAHDRISGGSSSGSAVAVGTGLVTFALGTDTAGSGRVPAAFNGITGYKPTKGTFSAQGLVPACKSLDTVTVLAPTVEEAKKVWLVMDQGPDDADPYAKTQQSLALWHADFRGVRAGGFTFGVPPQAALEHCSTEYQTEFAQAVERIKSAGGIPQEIKWKPFEAGGDLLYDGALLQERIACIGPDFIAKHSASFHPATKSLLESAMSKDVKPWEVFRDLHLQAEYTRQAAQIFEDIDVLLVPTTTCHPTVAAMEADPIALNSKLGYFTHFGNVLDLCAIALPASTYQTWAGEKLPFGVTLLGASGTDGKVFDIAREFERTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCS6</accession>
    <name>A0A9Q8LCS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCS6"/>
    <dbReference type="GeneID" id="71987821"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07943"/>
    <dbReference type="OMA" id="MKRIQQG"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00833">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16964" checksum="FF87D7EDE2101BB2" modified="2023-09-13" version="1">MGRVRTKTVKKSAKVIIERYYPKLTLDFETNKRICDEIAVIASKRLRNKIAGYTTHLMKRIQRGPVRGISFKLQEEERERKDQYVPEVSALDFTQNSESGQLDVDQETKDLLKSLGFDSIPVNVVAVQQQQVAERPRRFNDRNPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD02</accession>
    <name>A0A9Q8LD02_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_08675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71988553"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08675"/>
    <dbReference type="OrthoDB" id="2830640at2759"/>
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    </dbReference>
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        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
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    </dbReference>
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        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="52336" checksum="7C73C84048A08A7D" modified="2023-09-13" version="1">MEMLSHSTIMDQSRERFLCQAETEGRLSEQDSKYHIFSLQADGAIEHEVQFDVVSQAPASGKSEKHDTPRRTIDYQRGLNSALRCVLQSKRPKHRSGHPDALPFRSAEAMRTVFQNLSLPSAYFEIADGSPATAQSYTFKTQSHNPLRLELVAHCITKQGDWAVALTHSASTGSTTVFWSLDERIDSSRLSEDLLAFPQHAIHPMLIPCIMFAATLRMAVERRHMIKDRLQMLEDSIPRIGRTVSIISEKVHEQDAAFEDSHDFDRLFNLLHSCRKDQASRKGSFRDVIEQGFLYFESLLKKQPNEEHFQINAELKRWYDITWQRIESLMARDKDHIDRVENFSQTLYSLIQQREIQLQSSIARAAQRDSEGMKYIAVLGSIFLPASLIATILNVPVFQFARGPTLFGAYMAITIPFSAIVVYLCLSRPYWIKWRQGRSFTRRRGDVSMKRTATGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDY3</accession>
    <name>A0A9Q8LDY3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759825.1">
        <property type="nucleotide sequence ID" value="XM_047907510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDY3"/>
    <dbReference type="GeneID" id="71988240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08362"/>
    <dbReference type="OMA" id="HRTLHMI"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20891" checksum="C93606C1842A7A97" modified="2023-09-13" version="1">MSKRKAEDVCSPARSKQSCFQAPKWVHDGQHRTLHMISSPVRMSTASYEGDINMDFQQQSSHRHRRNGSRHGQQDIDMDCSYAQTAWIEYLDATRTQELPDVSREQFNQVVAQNEALEATVDSLTQDLTRAKSRISELLEAQRLQQYVYQNCAIEVSHMPRPGFQQPLYFAPHQSVPAPRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEV6</accession>
    <name>A0A9Q8LEV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional activator protein acu-15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760571.1">
        <property type="nucleotide sequence ID" value="XM_047903282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEV6"/>
    <dbReference type="GeneID" id="71984012"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04134"/>
    <dbReference type="OMA" id="IRCDGRP"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF4">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="712"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="744"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="922" mass="101404" checksum="EF958BAEBBE107ED" modified="2023-09-13" version="1">MPSAQLTNNLKRPADDASDVDRDDGTQTQPSTTPVHKLQRIDSSSGIAAADYANPNSIKKKSAGSSSRTGQACDRCKIRKIRCDARPGGCSPCLQNNTECKTTDRITGRATTRGHTEHLENENAQLKMYMVELQQQLRDSGVEPKAPPSAPAGYLPLGQWGSWGDQGWGMQSNSNGNSILSPHHTSRHRSSSAAAQLLPDFRPGCTGDNYLGVSSENDWLTPIEGTSLALFGTKIDLAEFMPSENDPASSAMSYRTFLTHAYGRTHTFAAQLPAYEQCKVYADWYFRSIQQFIPILHKPHFMELLERVYHQENYHPTSAETVMVHMVLAVINFQFSARNHNEQARHDSMAHYHYALSFIPDLVTGHKLEDIQALTLICSQLRNQPRPGAAWMFTNMVMGLAIESGLHRSSKAWQGSAMNQDPQRLEMRKRIFWSLLAFHVHISGKLGRPMPLRLEDFDIEIPEPLSDQLPDEPVTSKWKQCSWQAAIEGWKLLKIMMQVYASIYSIKSTGQYEINVHTLEKQLDDFHAQIPPELRGGPQTKDEDRVSALYLDMSVAECQLLLHHPSLCRSASPQVMSSNLDVCLHWSAKLLSSATQLKELKSLDTTWYYGTDFLAAIFTTLFANTERRDQMDSTDLQRLKHDMDQWLDVMGEVGDLLGTGSALQQAIKALVDFSIGNISRHISAKTAAAAVASAIAQSPTTQDSTQSQNQQAYDNSNSTGGYYPNGTNGDITAAQHQGYAETPQVHQEQTQNAYPSGNQFATYPNTQSNGIPGSAAYDTAAYSGEESKPVIDAQYAAHGATQQTPQPTNFMAAFQPQVTNGYQPNPLNPLAGSMNGHQVFPHEGPAAWRHFATSMMTNVSAPDDMHSAGLMASSSSHGSSAEPPIDLTAAAAMGNLQMPTGQMGNAWPFVQYGGVGTGHGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY0</accession>
    <name>A0A9Q8LEY0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Purine-cytosine permease fcyB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760558.1">
        <property type="nucleotide sequence ID" value="XM_047903062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEY0"/>
    <dbReference type="GeneID" id="71983792"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03914"/>
    <dbReference type="OMA" id="MAYEYEY"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="305" mass="33559" checksum="C47E3A2E4050CD51" modified="2023-09-13" version="1">MAYEYEYDVEKNRSVAGDVHNASSERSSQEKKRPSMGYEDGAVPGESFEVGNGLYAKIQRLAGRFHVEQRGIERVPEDERTGTGFKALLNVSTIWLSANMVVSSFAIGILAKSLFYLAVADAMLVCLFFNLIGITPVCYFSCFGPNFGLRQMVLSRFWFGWWGVKLIAIFNVLACIGWSSVNSIVGAQLIHTVNNDVPGFAGVLIIAFCTMIVCFFGYKVVHAYEFYSWIPSFIIFVIVLGVFAHSGDFVNIPWETGTSEMGNVLSFGATVYGFATGWTSYAADYTSTDHQPNRARESSSGPGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFL6</accession>
    <name>A0A9Q8LFL6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Conjugated with ATG12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Preautophagosomal structure membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATG5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760884.1">
        <property type="nucleotide sequence ID" value="XM_047904183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFL6"/>
    <dbReference type="GeneID" id="71984913"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05035"/>
    <dbReference type="OMA" id="SIQKAVW"/>
    <dbReference type="OrthoDB" id="272162at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044233">
        <property type="term" value="C:mitochondria-associated endoplasmic reticulum membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.620:FF:000004">
        <property type="entry name" value="Autophagy protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.190">
        <property type="entry name" value="Autophagy protein Apg5, helix rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048940">
        <property type="entry name" value="ATG5_HBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042526">
        <property type="entry name" value="Atg5_HR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048939">
        <property type="entry name" value="ATG5_UblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048318">
        <property type="entry name" value="ATG5_UblB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20637">
        <property type="entry name" value="ATG5_HBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20638">
        <property type="entry name" value="ATG5_UblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04106">
        <property type="entry name" value="ATG5_UblB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 UblA" evidence="9">
        <location>
            <begin position="15"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 alpha-helical bundle region" evidence="8">
        <location>
            <begin position="151"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 UblB" evidence="7">
        <location>
            <begin position="215"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="35316" checksum="7AF36EDD74085D9B" modified="2023-09-13" version="1">MPASASSIVALQSKIWAGSIALEIRLAASDCRTYNESDPYYVQYPRLSYLAFMLPRLHSFFAPSLINPEVLAHDAWLSFEDVPLKWHYPLGLLFDLFSGAEPADLEPPGVGDASNVAAEASTSTSTIPWKLTIHYTDFPDEQLIQLDTEGRAMQDMFINSVKEADFVRNGTARTIMLMSKDDSDNLWESVQQHDLQLFNTVNSKLLNPPGMELRHVPIKIYLPTSANKEGNNTIPEEGAAAGHLRVVQSLVPLQLPSKQPQTLGTALNGVLPTIFPSRRSPIYARPVLHGASVPLSARLDELGRAVAYTDGFLHVAVVMHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGT2</accession>
    <name>A0A9Q8LGT2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761265.1">
        <property type="nucleotide sequence ID" value="XM_047903957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGT2"/>
    <dbReference type="GeneID" id="71984687"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04809"/>
    <dbReference type="OrthoDB" id="3647606at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="356" mass="39422" checksum="08C3F869BBB28952" modified="2023-09-13" version="1">MSSQTQQSTHILFSCSHSAQVPVHLHEQSLQNPTMSLIPFLRKDLNETASLADSPSNISIPIISHPSPCGRDSCYNISTPTLQRQVLDQISTIRAHLSSLQVKYTDLGTQYHSYPLAIRARCANDPGCAMAHLQFGITTQPWEEDAFFESWINVAASYSDLQRRVMSPCFDAGSARCVRKVGKVLMQCYKQLAEIGELARMLEMGVEALESARKEQEGKIVISGLPKGEDRTIIQQTLQAAGIAKAKHLETLAVDADVQSVVVVQCKSLSKAQKARKLLSTFEACGVSVEKYTPAAAAAMQQSSYALKERRFAVKDETKMRKVAFKNVLRKIWGERMSGFVGVGMDGEKPWWVISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGZ8</accession>
    <name>A0A9Q8LGZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS-type efflux pump MFS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05728</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761681.1">
        <property type="nucleotide sequence ID" value="XM_047904876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGZ8"/>
    <dbReference type="GeneID" id="71985606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05728"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="333" mass="36074" checksum="2D7B748064CC0268" modified="2023-09-13" version="1">MAQPQPVHERAESLSSLSNHSDLEKSELPSNYNTTTTDNDLSRQKSTTPSEIEYPGPKETAIVMIAILLALFLMALDRTIIATAVPQITNDFQSLDDIGWYASVFMLTACSLQLLFGKIYTFYSPKWVFLVMIGIFEVGSALCGAAPNSVVGRAIAGMGSAGIMGGAIILMVSVVPLEKRPKYQGLFGAIFWLSSVIGPLLGGAFTTDVSWRCMTDETIGCFYINLPIGGAAMLIIFFILKPTTPAQPGLTLRQQLAQLDLLGELFLLPSIICLLLALQWGGSSYAWFSSRFIALFIVFGLTFLAFVASQILGPKTATITPRLLKNRSLIAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH94</accession>
    <name>A0A9Q8LH94_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761505.1">
        <property type="nucleotide sequence ID" value="XM_047903108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH94"/>
    <dbReference type="GeneID" id="71983838"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03960"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="394" mass="42576" checksum="576D8C1A40EFBF30" modified="2023-09-13" version="1">MRTTMRTNDASRQSSTRVGASDSRSGPSRRASTSNAQPGAVAGARAAYTRPARPTPIYGPPPPMRTESALSKMYERTVKAKDTVRDKCSTKAGSVMPVVNNLGKKASRAASNARASVNDFIRANRRRRPHGYNQSMIGGQESTRIATADAIALQNIETVPVFVARDRPAVDGFAVANSSANQPATQSQQNATETVRELRVNETALAALEGRPDPFSQVPRRGLVNTIDRARMRREVNIPRRQAPPPSPPLPLYKEHPTPTPTYRSCFSSGRPSCKDVTFENNHDRRVTLWDMAAPAPDKTPDQSPTDTMTEATVAAVAGPSRPVATELVNPRAINLDKPVPDSPESSFEWPSGMIPLTIAVQEKIVTKEAAAAVKADNPHGKHLVPAPAGYQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI5</accession>
    <name>A0A9Q8LHI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0664 stress-induced protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761874.1">
        <property type="nucleotide sequence ID" value="XM_047905637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHI5"/>
    <dbReference type="GeneID" id="71986367"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06489"/>
    <dbReference type="OMA" id="SNRLEDH"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13214">
        <property type="entry name" value="PH-GRAM_WBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PH domain-like"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="27999" checksum="8500D6D200B9DD27" modified="2023-09-13" version="1">MSINWVMLSPATNPPFTPLPNEQVVCVAPGKRIGFDLSTPKHYPGRQAQPYSLSHSNGSLYITNRRVVYLPDKPTETFKSFAVPILNLQDAHVTLPWFSANSWHAALRPTPGGGIPTSAGILELKLTLRDAGVSDFHSSYEKIRERLMQAVDVSNIDGDNAQAVNRMDVSNVNLDDLPAYSEESDGPLLPPTATAATVAQTQHQQRSQQLRDSGVGVDSDEAGSPKPQETPDEPPPGYAEAQMAGVQDEMERRAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHM8</accession>
    <name>A0A9Q8LHM8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762177.1">
        <property type="nucleotide sequence ID" value="XM_047904843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHM8"/>
    <dbReference type="GeneID" id="71985573"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05695"/>
    <dbReference type="OMA" id="IDSYESW"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="641" mass="70824" checksum="B84DE0C6903655FA" modified="2023-09-13" version="1">MTGNTPGRRTNLTDLPPELLEHITNYLPTASAIAGLGRTSKTLHAWVEKDAWKAFSRNAFPSLCPQITAPSYRETARTLTTVSKAWDKRAFIARYVEPHGSITSHPSGKQLNQWKPPRGQTLGFTPQLDVFEEIGPTWRDREETLAFSAGAEVCIRETARGAEDNVSWKTYRPHSAYEGRDDVTTLHLLRPEEGRTDASINFISGTANGDLQMIGLPDTVSPNQDVAITYFATQGLKVRSSSIYRSPGQPTLLAANLDDTKVALYTVDSNQSKIAPASQIEVHPPLRADGNPAPNHRAWSTAFLSPTTLAVGAGPSAAPLHIYTITDSGLSQRPTRKLALHNHEDGVDATISNQSPRAHLTSIYTIMPMPTSIASHDHGQVFLSGAYDGVVRLHDLRSQRDVEQAYIDPADDGAVYSILPRGREKLMVGTSRHNLLKVFDVRMGAKCYSHQDIHTNQSPNTGVEACDPESDYNIFLRNNNASFTTRGSNWSQGRNRSADSSVYSLASPSAHSPYVYAGVESAVYGIAFAEALDSHPDPTFFEPWSAQAEPHNQSPKHIRQQDNDFVNSKFKAEHIGNKNGSRTFEAKDVLGLAMYDQGANMKLCVQRSLWETWRAGSPRRRDRFFQGRLDERWKGAAEFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN9</accession>
    <name>A0A9Q8LHN9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762041.1">
        <property type="nucleotide sequence ID" value="XM_047905522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN9"/>
    <dbReference type="GeneID" id="71986252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06374"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF129">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="120"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="573" mass="63071" checksum="F60DB694E24168DB" modified="2023-09-13" version="1">MPAGNVLPDLYYIRDRYWLSISLLRHLVRIYTDYSGSLRLTSQLYLVRQHYILPGGTSVAYSKSAVLHQHNMSTLRTSFAKHRKPCDLPTTESTKSFWHKDPSALLLGHRSTRDLPKTADVVVIGSGITGTSVAHHLLTGGESDQKIDLVLLEAREACWGATGRNGGHCQPVFFEHPHDPSIGHFELKNFETLQSLIDEKDIDCEFVTQPGVRSVFSRGHLDQAEQAVHVVQKNAPELASRMRLVTDRDELSGLRVPTALGAIVTNIAARMWPYKFVARILEDLITSTKLNGTFNLQTLTPVTELASEVHRDQDFVLVKTERGTIKAKKVVLATNAYTSHLLPQMSDLIVPCRGQMSALKPFPSVSGEDRLRTSFGFSGDGLDDYLIQRPNESGAHLMFGGGRQHGPSLGITNDNQLDQKTASYLRGRLVDVLNLPEGGEKTSWTEMDATHEWTGIMGYSRDERPWIGALPAELSPSLPPGSTYLAAGFTGHGMPNTWLCGKAAAVMAKESLEGANVDEASVIASRETGLPEAYKISKKRIDAAMELEDVEAKGWAETDRGARAKRPFTSGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHY8</accession>
    <name>A0A9Q8LHY8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761324.1">
        <property type="nucleotide sequence ID" value="XM_047903250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHY8"/>
    <dbReference type="GeneID" id="71983980"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04102"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="122" mass="13745" checksum="2380E051FD9346BF" modified="2023-09-13" version="1">MSTSAADVITQQGTQIASLHQQLAASQAQFSALTRENMALKEARSEAEVKERELQDEVHTMHMNWLESERVRVKVARERDEAKADKKEAVRVAWAWLTAVDDGFVHDEVVGDAEALLKSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK5</accession>
    <name>A0A9Q8LIK5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762672.1">
        <property type="nucleotide sequence ID" value="XM_047904790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK5"/>
    <dbReference type="GeneID" id="71985520"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05642"/>
    <dbReference type="OrthoDB" id="2592744at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="34423" checksum="7A2A1AE3DD94CC91" modified="2023-09-13" version="1">MAIARQHASRIPVADLTAFIQAIFPIRSGDVPFLYHTPYSRSFNAATFFITAIVLSITPTAGFYASLHSGTKVGFLHRPFDLDRREVPRLATVLSNHKGFDEVLTVGYNVALAERIGLDVPNAQVIQGYKGNPERRIGIVGALKQTAKASEMQSRILQQFNGAFEGCFGFEGEGGTVESQLSNDDDVQAVAIMNAFHPEEVDRVLEVSQQNGLLPGNDAKGLLYLTGAVRQPGLLYALERGIKVICVGHRICEEWGTHHIAECLRERFPNLRVDEVYEDEEPREHTRHGKEAKEQQLSKRASDRGGVPVATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIL6</accession>
    <name>A0A9Q8LIL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fumarate reductase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06243</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762453.1">
        <property type="nucleotide sequence ID" value="XM_047905391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIL6"/>
    <dbReference type="GeneID" id="71986121"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06243"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006130">
        <property type="entry name" value="PRK08274.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF7">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="57597" checksum="9550785A107BB8F3" modified="2023-09-13" version="1">MPSNNNNDIANQPWDIIVVGTGAAALTSALSAATSIPGYAPRVLLVDKAPEDWVGGNGYFTAAAYRTQHGGLKDLLPIVSNVPAELEDKIDLPPYTADDFHDDLDRVTGGRSSRELGRYLVGESLETVRWLKEVGGVDWWLSFRRQAYEVNGRWQFRGGLHLTVEDGGKGLIRSLVKAVKDAGCTIAFDTAAKSVVVDEKGAVSGLEIERAGNVQRLVASSVILCGGGFEASPMLRQKWMGPGWQLAHTRGTPHNTGDMLLEAIRLGAKTVGDFSPGGCHSVAWDADSPQNGGDREKTNEFTKSGYPLGLMLNADGKRFVDEGIDLRNYTYAKSGRAILEQPGGIAFQVWDKDGQNWLRKEEYRDEIVRKVYADSMEELAAKLEQDGLRDSQHFARTIAEYNEAIQAHGEEYPDVQLNPAERDGLSTQSSRKQLALAKSNWAIPIVKPPFLAVKVTSGITFTFGGLAINPESAAVLRNDGSEIEGLLCAGEMVGGLFYSNYPGGSGLTAGGVFGRRAGQVAAMRAQRMSACSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIS6</accession>
    <name>A0A9Q8LIS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762519.1">
        <property type="nucleotide sequence ID" value="XM_047904948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIS6"/>
    <dbReference type="GeneID" id="71985678"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05800"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="32654" checksum="5C5BEDFE68E32F09" modified="2023-09-13" version="1">MGKYSAGLVFDLAAADPPRSSSWVSIPSSYRNSRSRQDSMMSATHHSNLWTSSRPLDEPSFDDFDDFDDVDDFEDGASLESGTMPAILAKRPVAITRDSSPSTRSLNGKPSHRAMNKHLRDLNGPWSLSKALSSGVPPALELQGFNSATRKAIIASPISLWISQSHYPSQIFAKETTTSSIPTRTERWYPPHNGTWSEWWTTSSAGMKGGYISTKSRCRWTKGSEIEHGDGVVFLTANLSMSGELFMAEVECLEMGWRAKQVWFVDRGRLVRRIVTLGDEGKRAETTLVYCFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIW4</accession>
    <name>A0A9Q8LIW4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sterigmatocystin biosynthesis peroxidase stcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762685.1">
        <property type="nucleotide sequence ID" value="XM_047905625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIW4"/>
    <dbReference type="GeneID" id="71986355"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06477"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF7">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040213883" evidence="8">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="26"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="250" mass="27652" checksum="8EDD893BF5B48B15" modified="2023-09-13" version="1">MKVLTLGTFGLATITHAYPGAVAEVLPRDGKNFTQDRVVHGLNAGLNFDPALGATMFGQALVANPAPNATFFTLDQLNVHNVLEHDASLSRSDAYLGNNHVFNYSVFAESTKYWTGPIMDRDMMANSKIARQLQSKASNPGYRFTNSTENFSIGEILAPFVAFGDRQAVTVENRLVDYFFQNERLPTKLGWKRTNETVTLQGDILRLSEIFSKAASLITEEDSGKGSTHGEPTKRRRDLHAGIFYVIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIZ8</accession>
    <name>A0A9Q8LIZ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71987495"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07617"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
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    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040169115" evidence="1">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="118" mass="12763" checksum="54E1D60A36E3F261" modified="2023-09-13" version="1">MRGQSLTWACLAGSLATAQAQFQLEENVFDTSYLTARQAKAAGKKGVMMMNRFALKPPPDLFIANSDGTNAGKFLGNSSHHDYHASFSQDGQFVVFTSERNGLGNADLFRARANGSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJA7</accession>
    <name>A0A9Q8LJA7_PASFU</name>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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                <person name="Stergiopoulos I."/>
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        </citation>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LJA7"/>
    <dbReference type="GeneID" id="71987606"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07728"/>
    <dbReference type="OMA" id="ENVPIYN"/>
    <dbReference type="OrthoDB" id="5405126at2759"/>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="42113" checksum="A2090AC90415C637" modified="2023-09-13" version="1">MASICTRCSLRLRRAAQTESQHLSKRSFSSTTSRQRGNLPSFHESSHEELQNVLSSVREKYFIPAYMHKQEHKLVTKQKFRQQLIDNPQTAIVGGEEITLQPINPREGWPHRRSIVAKAINGIINGETKDWLNLPMLLQGLNEGVKKAASDSLMEKIVRKAFQAKQLGVVIGCLHQAEQTGMTLKSDPVLRAFLAGLHDLAQESGWNKGALERALRDAKVISQLLESKKHGTEGTVRKDDPRIRPEVLGVFLELASVYAWKYDGKRDTEGLVKAYAERLLSNLSKRQIKPRALKLLERSKQWPMLQAIPIWHGLSLAEKILGKDMPQRQAASKAVAEYEVALRGLAAELEARNPAEGTYEHQALEAWRRCIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2L5</accession>
    <name>A0A9Q8P2L5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2L5"/>
    <dbReference type="GeneID" id="71980721"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00843"/>
    <dbReference type="OMA" id="YPAWYNA"/>
    <dbReference type="OrthoDB" id="5419608at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="18210" checksum="88A480BBC81AEFFF" modified="2023-09-13" version="1">MQYSFTLSALAATAFAQNNQNQDDQADQSVAGLASVISVLQTALPSSLIQEALTNSAAVASDISAEFAAGSTPAWFTALPTDVQTYLVPSQLYPNATATGTLISVGPTNSANATGYGNSTRSSSTSGRSTNTVTATETGEGSEETGASATQGESSSSSSAGASMPSAIVGMGLAGAVGLVGVLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2V7</accession>
    <name>A0A9Q8P2V7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc-regulated transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02032</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755659.1">
        <property type="nucleotide sequence ID" value="XM_047901180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2V7"/>
    <dbReference type="GeneID" id="71981910"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02032"/>
    <dbReference type="OMA" id="ISEYPWV"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000007">
        <property type="term" value="F:low-affinity zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071578">
        <property type="term" value="P:zinc ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF69">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="374" mass="40597" checksum="B3CCD18F40F2CBDC" modified="2023-09-13" version="1">MTDCTTGNEFDGRLGVRISSIVVIFIGSALGALFPVWAANHKGAHVPEWTFFVAKYFGSGVIVATAFIHLLAPAHEALTNECLTGPITEYDWVEGICLISIFFLFIVEVMVMRFAKFGHSHSHDHGHGHDPEHGRPLEAGSSSPKETDQQPQKYQDNPSKTELSEGAAESSVGGNDQCPVGPYAPGDDHLSHAREHVDSHGEPSRTFEPDSYTAQMTALFILEFGVVFHSVFIGLTLAVAGSEFITLYVVLVFHQTFEGLALGSRLGTMKWPRSKWWTPYLMGLGYAVSTPIAIAIGLGVRKSFNPEGQTALIANGIFDSLSAGILIYTGLVELMAHEFMFSSHMQKAPMGTILAAIGWMLLGALLMSILGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P358</accession>
    <name>A0A9Q8P358_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_00532</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755782.1">
        <property type="nucleotide sequence ID" value="XM_047899680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P358"/>
    <dbReference type="GeneID" id="71980410"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00532"/>
    <dbReference type="OMA" id="EYIVTHA"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF2">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="340"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="644"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1009" mass="113727" checksum="92DBF3725D46E740" modified="2023-09-13" version="1">MSLKKALHSFRPRSGSNSAATSDNESPAPKDGHRESRVGTGFSALSNGIGFGRHSTDSGHRPSTDLSPSPSRHSKDHHRGSHSPLGFLRRKVRGGSDDSHSSTEDLPLNREGEPMSRNQQRKHERQAEKEKHRQEVEARQEADRKRKEEMAKRAEEEETEEQKARYGTLPINYYAGQQKHEDRIDLRDLKPEHVGQMVCFRARLHNLRKLSAHLMFIELRQQTATIQGILHEHGSVSQHFLYWAEHLHVESVAVIKGVVQEPKAKQGEIIGVSIHNLEIHIHEMHVEATPDEPLPFTVHEAEVSKAETQQEGDTRHRVSDRARQGNRIIDLRTTASQAIFRVQSGICQAFRSHLHNIGFIEIHTPKLQGAASESGASVFKVDYFGRPAFLAQSPQLGKQMAIAADFRRVFEIGPVFRAENSNTHRHLTEFTGLDLEMAIDEHYHEVLRVLDSTFKAIFKFVYDNYREEIEVVKRQFPHEDLVWLDQTPIIPFAEGIRMLNESGYRDENGKELPEDEDMGTRDEIALGAVIKEKFKTDYYVLDKFPASARPFYAMPDPDNATLTNSFDIFCRGQEILSGGQRIHDAPTLAANMEKMKMDPKTLEEYMTGFEWGAPPHGGGGIGMERILMLLLKLGDIRNATMFPRDPKSLPYKPPVKQLRHPEASTMHPPWMGQDRVTAHMDFQPLEKLIANYGDASNTSWLEPKFEHWRDSNTGAAIGFVPHEGFAITIGDPLCHQSQYVKTIGGYLRYIKKERHLKALWLLCGQAVEEVLANKFDWRTLSVAAEQRLDPGNNPAAKDPEIQRKCRHAEKEGVKLHDIPIGTPIPQDVKEKVDKRIEDWLKNRKGKQVHLTDVHPWQDTEHRQYHYTTTKDGQICGLVILAQLSPDHGWQVKFALDFPGAPSGAIELLVLHSLKAAAQTGATSVTFGGGAAAKLTPGHNLKGTRVKVLAKAYHAIATELKLTNKSEFREKLGAQDDPIYVCYPPHGLGPSGVRAILSFFEDDDDANKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P376</accession>
    <name>A0A9Q8P376_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756081.1">
        <property type="nucleotide sequence ID" value="XM_047899828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P376"/>
    <dbReference type="GeneID" id="71980558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00680"/>
    <dbReference type="OMA" id="WGQIGRL"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="38011" checksum="CC3B081FDDF18302" modified="2023-09-13" version="1">MTDKDDQNDPVQQSIAATKAEYATLGSEDSLPILKAAYDRGLNTWDTANVYSNGVSEEIIGKALKKYSIPREKVVILSKCYGYVGEEPGTRGMMYGQKIAESKDHVNRGGLSRRAIFDAVGKSLKRLGTDYLDLLQIHRFDQYTPMEETMESLHDLVKMGKVNYIGASSMWAYQFAQLQFVAEKHGWTKFVSMQNHYNLLYRQEEREMNKFCHDTGVGLIPWAPLCRGHLARPPSEYGNTIRSAGEQRNSIFTTGQSESDQEVIKRVQELAERKGWKMSTVALAWINKRISSLIIGFSSVERIDEALEVRGKTLTAEEEKYLEELYVTRDVQGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3G2</accession>
    <name>A0A9Q8P3G2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="99"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="528" mass="58720" checksum="F69A6EE51F4AFA68" modified="2023-09-13" version="1">MDDDEKQPVEAVEEETGLKPTYTHSKEEEHDQYNDKTPTAKRGLGYSEADLENHRLSLHHAQSHVSTHDAAIVHHDHDQHFEAGDEIYDKFSPRRKMLIVSIMSFCSFLAPISSTSILAASPEVVATFDTTGTIFNISNALYMLFMGISPLFYGPIGQTYGRKWTLSIAAVTFTALSIGTALSPNLAAYFVFRMLTAFQGTAFLIIGGTVIGDIYKPIERGTAYGWFMSGTLIGPAMGPFIGGIIVTYVSWRDIFWLQTALSGFSTVLVIFFLPETIHRRRSDELVGLSRAKKAKQLWAWVNPARVLFLFKYPNLIIIGLASSSLVWNMYSLLTPIRYVLNPRFGLTTPLQSGLFYIAPGCGYLFGTFFGGKWADRVVKKWIIKRGEHVAEDRLHSSLITMGIVIPACMIVYGWSIEKEVGGIPLPVIAMFLQGVAQLFCFPSLNTYCLDVMQKRSSEVVAGNYFMRYLFGAAGSAAVLPIVDAIGVGWFSTISALFVFLGAFGTWCVTVWGRQWRDAIDKDKEGEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P666</accession>
    <name>A0A9Q8P666_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 10">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_08374</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 10"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759201.1">
        <property type="nucleotide sequence ID" value="XM_047907522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P666"/>
    <dbReference type="GeneID" id="71988252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08374"/>
    <dbReference type="OMA" id="PYLENYM"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="11">
        <location>
            <begin position="372"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO14835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="455" mass="49928" checksum="24C4F461733CCBC4" modified="2023-09-13" version="1">MAALNGDSQTTTRSRSKDMAYILSRAGACTDASTFTPGQAAFDSLSTTKVLVIGAGGLGCEILKNLALSGFKSIDVIDMDTIDVSNLNRQFLFRQSDVGQPKATVAANFVMKRVPGCQINAYVGKIQDKDESYYMQFNMLICGLDSVEARRWINATLVGMVDEQNQESLKPLIDGGTEGFKGQSRVILPTMTSCIECQLDMHAPRAAVPLCTLATIPRQPQHCIEWAHIIKWEEERKGVTLDTDDPEHITWLYQTALKRAQEFGIQGVTYTMTQGVVKNIIPAIASTNAIIAASSCNEAFKIATNSAPFLANPMNIPTGVDPDDYMADMDGEFMPAPDNYMLYTGDNSVYTYTFGHKRKPDCPVCGNLPKDLSVSGDTTLGELVESFAERPDAQLKKPNLRTGEKSLFYSSPESLRQQTEGNLKLKLKDLIEDGEIVAISDPAFSIDFNYRLSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P686</accession>
    <name>A0A9Q8P686_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759261.1">
        <property type="nucleotide sequence ID" value="XM_047906994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P686"/>
    <dbReference type="GeneID" id="71987724"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07846"/>
    <dbReference type="OMA" id="IFVYFYD"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040493061" description="Thioredoxin domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="39"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="243"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="712" mass="79972" checksum="86451FC970FB88ED" modified="2023-09-13" version="1">MRSSTILRWLALPFLVYATAAPPSEPQIQDGLPGKRLVKRAGDPDDDAPQDTVFNDKKVPAIQMLTGDTLDETIKDGYWFVEFFSPYCPHCISFAPTWQTMYEFYYTSEPVPQSPGSGETHNDLNSFKRYYNFNFAKVDCVANGDACSEKGVGSFPTVILYKNGKQIEKQTGQKDLSQMSKWIESILETIKPGSRPKGGPMLPKVGAKEAPAQPAPAPLPLPLEDKGDSSSSAKVTLTGTRIAEVAKETPNIAGRSMGLTGENFQRMVTTTRDPWFIKFYAPWCHHCQAMAPNWQSMARQMQGRLNVGEVNCDVEKRLCKDAKVRGFPTLLFFQGGERIEYDGLRGLGDLISFANKAVSVREGVIDINAAEFEELEKKEEVIFLYFYDQATTSEDFAALERLVLSLVGHAKLVKTNDPELSKRFKISTWPRLLVSRDGKPTYYTALSPRDMRDYRRVLNWMQSVWLPIVPELTASNAKEVMAGRLIVLGILSRDRPEDFVVAKREIKNAALEWIDKQTQAFQLERQELRDAKQLRIEEAEDRNDQRALRSAKSIRINMDDIERKEVGFAWVDGVFWERWIRTTFGISVADGEKVVINDEDNHRYWDVTMTGNPIVPSRTSILETLPRIVANPPKIAAKSTTNAIGHVWWVVKGQFTEHPLVSASMLIGMLLLGAIYGRRHLPSKEGYIKLTEKSGMNGLLGGNAGNGQGKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M5</accession>
    <name>A0A9Q8P6M5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS-type transporter M6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08011</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759666.1">
        <property type="nucleotide sequence ID" value="XM_047907159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M5"/>
    <dbReference type="GeneID" id="71987889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08011"/>
    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="93"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="568" mass="61519" checksum="74069B77299CD112" modified="2023-09-13" version="1">MANHEHDAVDCDIQTSVVVVVLVGKHEGTGLDEKGCHGLDAAAAARSSSSASSATSREDQAGTPPANDIEALRSTATDSEPWSVFTIQQKRFIVFMVALASFFSPLSANIYFPALNTLARDFGTSESVMNLTLTTYMIFQGLAPTILGDLADMAGRRPAYIIGFAIYLGACIGIASCNSFVALLILRCLQSSGSSSTIVLGSGVVADIATSAERGVWMGWATSGPMVAPALGPVLGGLFAEFLGWRWIFWFLVILAGTFVVPFVLFFPETGRNVVGNGSIPPQGWNMSLVNYLQQKSRPALGRTVSQRSDRTAQEQLKNKRKLRVPSPLKTLHVILEKDVGLLLFYNSIIYCAFYDIMASAPSLLQQIYGFDALKIGLCFLPTGIGCFIAPVITGKIMDWNFRRIARNTGYEIIKGRANDLRTFPLERCRIQVALPAVLLCDAAILCYGWVMQAETNLAVPLILMFLAGFGGTSAFNVLSVMVVDLYPLSPATATAANNLVRCLMGAGATGVIIFMIEAMGRGWCFTFFAGVVAALSPILWVLEKWGPEWREARRVRVEERQAGTDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M8</accession>
    <name>A0A9Q8P6M8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759368.1">
        <property type="nucleotide sequence ID" value="XM_047907880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M8"/>
    <dbReference type="GeneID" id="71988610"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08732"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF11">
        <property type="entry name" value="AMIDASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="572" mass="62373" checksum="D22251D6EF54EE84" modified="2023-09-13" version="1">MKYKGMTCSSGSPALVHLVANEDSFVAERLRAAGAICIGRTNTPPMMASGMHRGVHGRAESPYNLEYLTAAFSSGSSNGSGTSTAASFAAFGLGSETVGVWPLYPTCDVIVPHTRSVEDMMAILDVLTVVDRTKEGDFWREQNFVEVPHVERPSSHLDLKSSASGSLRGKRIAVPAMYVGGQDPNAKPTVVSKDVIALYQRAKKDLEELGATVDETDFPLVTNYEDDSVTGHTNNVVGFEPDWNGKERGELVAYLWDDFLKANHDSKYPGLSSVDGSIMFPRPPGYIPDRYMEHKNFMNYPGLVELAKNRGAKTIWDVEGIAKALPALEAQRKRDIEDWMDQNEIDVVAFPSAGDVGKSDLDTNDESARHALKNGVKYSNGNRALRHMGVPTVSVTMGLMHESRMPLNLTFAGKHGQDSELLKYAYDFEQHAKKRIAPPVTPALESDQIVDEPRDMPPSDRPGSSRFELRVASARRVSPNEIEVRGSIEGPSSESIKLEAYVDGKAVQAPAIKVDGNSWSFKDVYTHYLPVIPLYGGVGQVVNHALVVILARAASQVAGQLVLVDQNAALED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6S3</accession>
    <name>A0A9Q8P6S3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759680.1">
        <property type="nucleotide sequence ID" value="XM_047907610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6S3"/>
    <dbReference type="GeneID" id="71988340"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08462"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="22483" checksum="B9078B41F26160E8" modified="2023-09-13" version="1">MAEVEHITADNDSAIELSRTTKRVAFTDPIHSEIPPPPLTWPQRIECILATMPSCCVACMFWECCDDDDAGSSTVLSHASPAPRSPPDDSSLLPRDHAKPYKGDLTYFGAPTGREMCGYECSGLFAAVHPAWFTVFSIPEKSYPEDPICGRKIMAWTAKGNVTLEACGMCDHCKKSTDLDVSPASFSMLGSVTERRISMEWKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6W4</accession>
    <name>A0A9Q8P6W4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759800.1">
        <property type="nucleotide sequence ID" value="XM_047907473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6W4"/>
    <dbReference type="GeneID" id="71988203"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08325"/>
    <dbReference type="OMA" id="EEYWLET"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28147" checksum="2EBD45A3D329AC33" modified="2023-09-13" version="1">MLSSIAIRTLLEAKSSTDIQTVLATVPLTTDSASSTVFGTYELLEHVLLALPFHDLYVCQQVARSWRDVIHRSNNIQQAMFLLADGPPLKPVDDTYNVFGGRTRALYRPAPVRLNPAAEVVGLYNQPSGRGHRLPLATFGISDQNVFLNFDVKGIPIYETKILAADASWRKMLVTQPPIVAVNFDFIRREPHGGSLDAYNPTGVTFGDLHDWSVKLAEEYWLETGHDPELSFESISFCLFHPFTEDGPEEAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P712</accession>
    <name>A0A9Q8P712_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759965.1">
        <property type="nucleotide sequence ID" value="XM_047907917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P712"/>
    <dbReference type="GeneID" id="71988647"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08769"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="60"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="559" mass="61065" checksum="DCE501EF919D1DFF" modified="2023-09-13" version="1">MATEEQDFPSEDTTQAKETSPLLSKASDRRTSTDIAESSRTESHGYVKPEELSASQLAAILCSTYLGIVLAALDGTMVATLTASISASYHSLTLLAWLASSYYIANSVLQPLSGKLTDIYGRRAGLVFSNLFFGVGNLICGLATNESLIIFGRVIAGLGGGTLSAIPLFIASDLVPLRKRGVWQGYNNICYGIGAGLGGVFGGWMNDILNWRWAFLALVPMTVISSILVGRFVNMPEIVVYTKQEKDAKWKRIDFLGSSTLVMAIVLLLVGLNSGGNTVGWTHPTVLLTLPLSGVFLGLFVYTEVYIAVEPVIPVHLFRNPTVVAGCLTNWFLTMAQIALTFYAPIYFQVRGHSAFGAGIRLIPSSVGAACGSILVGIFMRATGKYYVLNIIIQALFLIPMAPTAQFGLHTPDWQPFIYFFFSGFAYAGMLTITVTALIASVEQQYHAVVTSAAFAFRGTGSTIGITICSLVFQNKLRQELWSRFQYDHDGARIVERVRDSLKEIRYLPKDMADDARESYMEALTAVFWTIFALAAVGAVCSLFMRQHTLHTDLARRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7C2</accession>
    <name>A0A9Q8P7C2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tetrapyrrole methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760103.1">
        <property type="nucleotide sequence ID" value="XM_047903203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7C2"/>
    <dbReference type="GeneID" id="71983933"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04055"/>
    <dbReference type="OrthoDB" id="3641227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19916">
        <property type="entry name" value="OphMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="432" mass="47901" checksum="E2F0FEEC56DFC26B" modified="2023-09-13" version="1">MPSQSIWSHIAELTRGGPVPKDVPHKGELVVVGTGIASLRQLTVEALDYIQRADVVFYATLDAVTEAFIKQHAKAAENLYQYYDTEKNRNATYTQMAETILASVRKGNMTVAVFYGHPGVFVTPSHRAIYIARQEGYKAKMLPGVSAEDCLYADLDIDPASSGCSMYEASFLLLEPDRLDSRHHLIIWQVGCVGKEAMVFDNKELYKLADYLEAEYGPKHPAIAYLAAIQPFNDSKMDHMTVEDLRDPEKVRSIPINAGTTLYVPPKKLPANPQAYKDIEIGYKLGLTSAFRISHPELDVAETYSEIEKGWCEELVSWTPPKSYIPNAATPALRRIAIKLALLHHRLHGSMSLEDIANAATAAEPSLTTDESDLLKQSVGFLDSMFNKERPPQSVTTSIVRSVVPPIVTQLNIIRKDGTVMMGDGKPSIYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7P4</accession>
    <name>A0A9Q8P7P4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
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        </location>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="UJO16334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="526" mass="58247" checksum="2E049D7B466E87B3" modified="2023-09-13" version="1">MHSKQGGSTVLASKPSSSFSTAASSSAASATSAGTSRSGGSRLLFGEIDTSSERSTESYASVCSFVLCDSSTFLKFWLEDKCRERLLRRLPKQDLANLRLTCHDFSVRAAPALFEDLSITFKTNIFARPSKLAALDRLGFYVKKLHFNVPHTAQSFLPPLIEPQTGAELSFTYTPQCEPSTARRPKYGDLETTEILSRQYPPIFHAATNVPGFVKAFSAFVDLQHLAVSCPGYDASNRYRRSVVDYALISLRIAIEKNSLNALDTLTLSPIHAGGIMYLSPLLGFGASPRSASRWSRIRHLTIHSTVLSTVPNSWEPDQFKLLQTYLRNFQSNLETLNFRWLRKGPLPVQGGSTHTTAPAPVTGTHPAHSQAATAQKAKKPRALHFPKIKHIEIENVSASAMELSSFVHSHRRTIEELNLEDVELTTGTWEEALAPLTKRHRRPLPRTETAVIPIMLSPTAELGLFPAPMQRLEVANEEGGRKSVRLSKWLQSRGKAPSAKKVREGLLGCEQQLRKMLRGSAFPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P843</accession>
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            <strain evidence="3">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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            <end position="105"/>
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            <end position="251"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <sequence length="257" mass="29218" checksum="CAFFBA3861828F46" modified="2023-09-13" version="1">MTSAFRRTPSRMSNEYILFDLPSRGTPTGWSLNPWKARLVLNYKNLPYKTQWVEYPDLAPTYKSFGIPPNDPKTNAAAEYSSPAIKHPDGHFTMDSLAIAHGLEESHPSPSLHLDSPVNERAQTAILDFQKALAAVIMPRVPEMLLNPPSEEYFRRTRAKRFGMELADLAKSEQAGETAWKNAEPALEKIKALLCEDESGPYVLGKEASFADFILAGAWRFYERMDKDGDLLGRIMKFDESFPRHHEACKKWLERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA29</accession>
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        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
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    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18662.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="198" mass="22609" checksum="965C51F7794E68E3" modified="2023-09-13" version="1">MEPRRPPEYHLEIAADRQSIRDVVKGILHTIFFHRYFTPLIPSTHEILDQTLPYVSSEEVESLILKQTQLLLRHLDAASSSSGAQTSPTSRPRGQLVVQFLEKKRRKGWFVAKADEETVWENWVIDVTLTTARSEPEAVRNRRLMERGLEKAAMKIVGIVNRERGHIPPITTNESNPFPYNILVNPKEGGWGKGMGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAF7</accession>
    <name>A0A9Q8PAF7_PASFU</name>
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        <submittedName>
            <fullName evidence="6">Esterase</fullName>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="102"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38544" checksum="B25CD1DE76EE56F7" modified="2023-09-13" version="1">MATMANDIKDHAATRQPTIKVTARHDRSFMVMLLQTFIRPFNQRLVSHSKEYPAGSPQLPPHRKAKKKLDISERKVDDVYLYRLSPKHSPSNEKNTRKRRLYYFAGGGWQMPASSEHWSFLTELCLNLPETAITLVSYPLAPHSPAPIAFPMLMRLYRTLMQDAANANEEVILAGDSAGGNIALALVIAALAEDAASATCPPCPAAILALSPSTDMRRSNPTMKEIEKLDPLLRIPFAHSTAAAWCGETSQECQAWERSDVRVSPLLADLGPLAKRGVKVHGVTGRYDILSPDAVLFREKCEEAGVEGEWLDWDKQIHVFPLIFSFGFREGIEAKDWILEVLRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBC7</accession>
    <name>A0A9Q8PBC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763708.1">
        <property type="nucleotide sequence ID" value="XM_047906383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBC7"/>
    <dbReference type="GeneID" id="71987113"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07235"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="138" mass="13520" checksum="CD87C4E028987757" modified="2023-09-13" version="1">MNNPNSFPPYAGAFPYTCPLAGLSGLALPMMGMGGAMGGMGAGMQGTPNLMGNQGMMGGNMMGGPSTMGQGGHFGGGMGGPTYPHRTYRRLREPGAAHMGGAMMGGQNMMGQRGQFGGGMGGPMGPMGGFGGGGMGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBD6</accession>
    <name>A0A9Q8PBD6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Pectinesterase</fullName>
            <ecNumber evidence="4 11">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07605</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in maceration and soft-rotting of plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pectinesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="4 11"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763673.1">
        <property type="nucleotide sequence ID" value="XM_047906753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBD6"/>
    <dbReference type="GeneID" id="71987483"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07605"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000014">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF127">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040534356" description="Pectinesterase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="12">
        <location>
            <begin position="30"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="34076" checksum="878A06A1B45B0C79" modified="2023-09-13" version="1">MKLFARLLAFASLALAAGRTSAPSGALIVGSGHYATIQAAVNALTTTTSQQSIFIMPGTYKEQVTIKKLSGPLTIYGYTTDVSSYSANQVTVTAANSQMNQPNNDATATIRVATPNFKMYNINAVNSYGKGSQAVAVSASAANQGYYGCSFKGYQDTLLAEAGAQLYAHSYIEGATDFIFGQHATAWFEKCTIGVVSATLGYITASGRSSADSGYYVINNSVIGAAPGQSVSSGAYYLGRPWGNYARVVVQKTSLSNVINAAGWRIWNTGDERTEHVTFAEYGNSGAGATGTRASFASKLSTALTIGQVLGSSYASQTYVDTSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBL4</accession>
    <name>A0A9Q8PBL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763842.1">
        <property type="nucleotide sequence ID" value="XM_047906810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBL4"/>
    <dbReference type="GeneID" id="71987540"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07662"/>
    <dbReference type="OrthoDB" id="3231000at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="24401" checksum="017CA504C12AA5DA" modified="2023-09-13" version="1">MPFPRRRQKGDLEAASTVPRNMGPVRKNERPAGLQDAIDELDERQRLYWSRWEGREHDILPHTDAGGDAYYIGDIYDGLRCAQEWELDNPGPYLQRIRALSSESPHLMYLAHWMEVTASPPKWTWLKHFPENRALRAARTKVGIVDLSQNAPATVTEYKDTTSLEQALALASGHLGTGTFRARLVVVEYLSRDVIEWYSRKRPPSQLRVDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM3</accession>
    <name>A0A9Q8PBM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrovirus-related Pol polyprotein from transposon RE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763822.1">
        <property type="nucleotide sequence ID" value="XM_047906453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBM3"/>
    <dbReference type="GeneID" id="71987183"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07305"/>
    <dbReference type="OMA" id="LMENNTW"/>
    <dbReference type="OrthoDB" id="3768101at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="2">
        <location>
            <begin position="104"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="243" mass="28191" checksum="FEFBCBD506219F53" modified="2023-09-13" version="1">MFHRNDSNEIVRDITKDDNWSRSNIAPGAATSGRRRPAVEDSDDIDEYQEQEEDDIYSEEYRAKAREALKNHNFRTTFMTATTLAAFENSRQAIQAEYDSLMENNTWEVVDLPAGRKALTTKWVLKKKLGAHGELLKYKARMVARGFQQVEGYDYTETYSGVVKASAYRLLFALTVLNKWTCHQMDVSTAFLNGEVFEDIYIYPPQGYPHPGKVLQLRKALYGLKQSPRQWYRKLRQWLLDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBT3</accession>
    <name>A0A9Q8PBT3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763924.1">
        <property type="nucleotide sequence ID" value="XM_047909525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBT3"/>
    <dbReference type="GeneID" id="71990255"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10377"/>
    <dbReference type="OMA" id="FCDARED"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="31091" checksum="10DB023B10E80641" modified="2023-09-13" version="1">MLAARLRPAATQFGKFIVPLRARYSTEQSYEHIKVSSPRPGVGLVEINRPKALNALFTPLILELNSAMKAFDKDSTIGAMVLTGSHKAFAAGADIKEMSTKDFADAYGDDFIESWSDLPNTIKKPVISAVNGHALGGGCELAMMCDVLYCSEKANFGQPEIKLGVIPGAGGSQRLTKAIGKSRAMELILTGKNFSGRDAFDWGLAARVFSTPEECVDGALDTAEAIAGYSRIAVKAAKEVVNKSQDLGIREGVEFERRVFHGLFGSEDQKIGMKAFAEKKKAEWKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBT7</accession>
    <name>A0A9Q8PBT7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763959.1">
        <property type="nucleotide sequence ID" value="XM_047909736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBT7"/>
    <dbReference type="GeneID" id="71990466"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10588"/>
    <dbReference type="OMA" id="EGIAHNC"/>
    <dbReference type="OrthoDB" id="3621732at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15483" checksum="B5847EFE2D790282" modified="2023-09-13" version="1">MDQTPIQMIATHVEGIAHNCVKSLNGRNFSPSASGWNQMAAIFRADSEHPQGGIAEQGLEEHLEMQRQIAQEHPQYRLRLLDLHTEVDERAGSASVFMTVEATGIPPGVIRQSVGVSKFQLIDGRWLCVRYGGARGMVGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC72</accession>
    <name>A0A9Q8PC72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-rRNA-processing protein TSR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764154.1">
        <property type="nucleotide sequence ID" value="XM_047909008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC72"/>
    <dbReference type="GeneID" id="71989738"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09860"/>
    <dbReference type="OMA" id="QSNWGGP"/>
    <dbReference type="OrthoDB" id="263560at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="23960" checksum="D47359B2A4F33E5D" modified="2023-09-13" version="1">MATAPAPSGPQPTGGLALPPTPEQLQSAFDNSIWYLLSLWPILHDAVSNGWGGPESTDKRDWFAGAISDLLNSRKEPDGPGTDQEDMEVFLLQIMQDEFDCFVEDESEVKVAGEILLVWKRMREERSLDAAREVEHRYRNRGQMRSSIKVQEVNQDLGEDEEWDGFEDEEGDDAEMGEPEEAPRLVPATVRERVEPVVDDDGFMKVAGKRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCK9</accession>
    <name>A0A9Q8PCK9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764331.1">
        <property type="nucleotide sequence ID" value="XM_047909757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCK9"/>
    <dbReference type="GeneID" id="71990487"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10609"/>
    <dbReference type="OMA" id="GWAVDNI"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040423331" evidence="5">
        <location>
            <begin position="27"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="61"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="51506" checksum="07E32B976EC8A568" modified="2023-09-13" version="1">MANGKSNMLRMLFCFVHLLLFARVQAVTNTTLSCCAQLHRQLPQKLFAYNDHMIPRWSKTADLTPRCSFFPTDAEEVSVALRILANSACPFSIKSGGHSPWPGMNSIDDGVALDLGWINQTTLANDRSHVVLGAGGTWGNAYAKLEPYGVLFPGGRASEVGIGGLTLGGGYSWTTPRTGFVADNVISYEIVLATGSIVIANATSNDDLFMALKGGGNNFGVLTRIWLQCFENHALWGGVAAVDVTRTIGSFLVNTASDHESTLHRPFMDMSPRLRNTLKKKTMAELSEELSAAWPVGQRYLTTSVGIINDREMLQNVQLSMESFYRSTSNAIYPSTFQCTFVYEPLPHFYTAQGELQSGNMLGLNNTSDDYVIVLLQPRWEDANVDLTMYHEAEQWVKNLRNTYPDKVMPLEYLPYAAPWQDPLGSYGEQSLEFMRKVGEKYDPDRVFQKLVPGGFKLDKTGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD36</accession>
    <name>A0A9Q8PD36_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="12">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09838</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ISN1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="12"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764697.1">
        <property type="nucleotide sequence ID" value="XM_047908986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD36"/>
    <dbReference type="GeneID" id="71989716"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09838"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028836">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO20331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="415" mass="46261" checksum="43F0CD1D55887AA5" modified="2023-09-13" version="1">MTTRYRTHRRDQFIEWIKGLLAVPFVLLSQPTNIHEDDKPTVAQMAQNAHERYSQIMRDVEGLIADHLAHTKRGTESRSKLKLLVPTVGTFFTALPMKDAFEWQDQRRFISSRRFVAPSFNDVRLILNTAQAMSLVRNSRLELMTFDGDVTLYDDGESLTPENPCIPRILDLMKKGVRIGIVTAAGYTEAEKYYDRLYGLLDALAANDIPPHQLIVMGGEANFMFAYAPKVDCKLEYVPGEQWKLPEMHSWTEENVTALLDVAEDALKQCITALSMPVSVLRKSRAVGIYPPKGVKLAREQLEETVLVVQRILELSLAGQLLPFCAFNGGNDVFVDIGDKSWGVMACQRYFGGIDGGKSLHVGDQFLSAGANDFKARLACTTAWIANPGETVALLDEIQQLSVARGRSHSLNSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDM2</accession>
    <name>A0A9Q8PDM2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764872.1">
        <property type="nucleotide sequence ID" value="XM_047910722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDM2"/>
    <dbReference type="GeneID" id="71991452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11574"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="187" mass="21663" checksum="55272EF55D521651" modified="2023-09-13" version="1">MKSFLDLPPEIRNTIYEFAVTCDNDEDCRITACAPWPNAADRPIQELCMEPALTRTCRQIRHESLPMFYSMNTFCSDSNHFTLKWLQHLRPEKYVALTSLRVGDEHFAPLSLTYAEGQFAWFTLEMGSDDLLQRGVLRVPMRVEGEGVLWVTLADLLSFERGFVEWVSDTGRRFTTLGVFRKRRSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDM4</accession>
    <name>A0A9Q8PDM4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FMN hydroxy acid dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
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            <name>FMN</name>
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    </dbReference>
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            <end position="442"/>
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            <end position="26"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <end position="90"/>
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        <location>
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            <end position="689"/>
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            <end position="760"/>
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            <end position="786"/>
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            <dbReference type="EMBL" id="UJO20969.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="1034" mass="114768" checksum="65BABBF64E6A630F" modified="2023-09-13" version="1">MRSSIACIRCRRSKVKCVNNGVGTACRSCENSGRECTYPRPITGGSRRRDSLSGRPDVYSGGGGGQDAERRQRPRKSTHTFVANPLSTNRDSPRPLLDALDPNILTPQCWQEMFDIFQTHYSADLPFLHPPTFLKPLRNASLQLPPAVPGFNAEQTPSARPPASTEFLLAFLALTARFHPRLVAHHSPPSATRPSNPLIASEYYAAAANERLASIWIDGKALDIERTQAILMLGLHEWGMCRGGKAWLAVGIAIRAAQAMGLQYELDLDDEPLSRSLALNGEAERLGMESGRKNSASGKSAEDDFILQEIRRRTFWSCYIMDRYLSSGKYRPQMLHARELRIQLPASERSFLFAEKVRTLMLGEEDKAVTGLGRAEVQNQRQQSVMLGTSSTPEPHMAPSPRSLAMQDTDEEKGRLEVGADEGLESRYIKILEIYGKVIKWSCSGGRRVEEHPPWDHRSEYNNLHRQCREFKASLPRQHTLTPQNTQAHISLKTSTPYILVHTVYLLCQIMLHREYVPFIPIRCSKPEGPLDPPIFAPEKYSVPSGFWEEIARECFRSAREIMDLVRTCQEWSALVETPIVGFAVYTVAFVGVYCINFPWMDPDGYMCTRPDASKPPNAKIGESKGFEAARKALEMIGTMRTRLHMADGWFKTINRMHRYFRKMKSDYRKNSHVIESSSEGDSPISTRHLSLREGGLGGGLDEFKLLERTLKDFGNLEDQDVEMTDANRPDSRPLDGVYDDSNSGTTVKSEEIGNDRVERTQSAPDASKAEGGAWSAINAAPGAAASRHPSISTPSSGQFRSYDQHYQQHPHQPPPPSLLQSQSQSQSQSQSQPQSQPQRPTPPAHPQQPYSQNQLNNFRPVYGDTPGSAGPPPSLTSPAAHSTSASTPSRSQPSPPYERHQSTYGSWGTHHTPYGMQAPPPPPPNPYTNGHVHQHSHPGAMHPAPAHSAYPQSAQPHVSQHLHPQQQPMPETQQAWDPMAKEAWLNSIDTRLGGDDVAAFVDGGELAEWANMAANQGFGGGWLSTVWGGPAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEB4</accession>
    <name>A0A9Q8PEB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11062</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765259.1">
        <property type="nucleotide sequence ID" value="XM_047910210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEB4"/>
    <dbReference type="GeneID" id="71990940"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11062"/>
    <dbReference type="OMA" id="STQEWCL"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040449096" evidence="4">
        <location>
            <begin position="27"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="581"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="627" mass="67476" checksum="8956721BF4D9274A" modified="2023-09-13" version="1">MLTPTPTSTLLATILLLLLLTPSTLAQSPPRYYTVWSSVIFQRTGERTPEIIGDSSLPITLTSTGANQAQSAGQFFRNRYIGTGTTNTGASNGTNGAGNSTARLAGLDADIYDELQMYATALDQQWNVATAQAWFQGFYPPFAPGANRSAGAVIEGEEDVLADGSYVTGPLNGYQYPYIHVTGALDPNFIYTGANWNCPAFTRQSRDWTLTPQYSVTEEEFEGIYAATGSAVLRGLVPPEAWGYNNAYAVYDYLQYQNAHNTTVRDALSTLRDVRTNTSYLTQLSWLASQQQYAMLGNLAALNPYTGASSLQTVTGSISTLPGNMLASKVLAQLENAIASAGAQFKLNVLFADFYPLMSFFALAGLPGLNSNFYGIPDYAASAVFELFSYENSTNATYPGAESLYVRFSFRNGTSGVEDEFRSYPIFGRGPDATEMPWEEFQTQMERISFGGNEVVPEWCNQCGSPSLFCAAFNSDLTASGSRPYRGWRGGSDDDDGMAPAVAGVIGAIIALAIAGIIFGMAMVLGGVRVRRDGSKKRSELGGFKGGQKMASDQDLTIPKGKDGVTVGASVVDAPMSPSGGHERIGSWEMKNAEAGRGLSARPSMEQRENPFHDPEGLRPVQSREVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEJ7</accession>
    <name>A0A9Q8PEJ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-mRNA polyadenylation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765370.1">
        <property type="nucleotide sequence ID" value="XM_047909977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEJ7"/>
    <dbReference type="GeneID" id="71990707"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10829"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="34621" checksum="B949F379BF74F2E6" modified="2023-09-13" version="1">MDEDDDDLYGGGSADQQNQQQTKEEDEDEHKMEVSEEEEDDDDSDDDVQITLEKPEGAKASEPPAKQQKTKHERTASESKPATSSTPIKTEGSTAPPTQVKTTLTHNGKEGKDFPEVRSKNPVDVNAIPTWTNGKPLTAVDIDADLAENSKPWRLPGTDATDFFNYGFDEYTWASYCVKQQMIGNQIGQIKQEDAQMKAFMGIGGDDNKQGGGGMPPMPPGMDMNDPNAMANMMQQFGMDPSQFMQGMNGFGGGMGGMPGMGGMGGMGGQGGGQQFQQGGFGNGQNSETQHNSLHHSSGSEFLLWCTMATASGQGSELGHVPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF32</accession>
    <name>A0A9Q8PF32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765651.1">
        <property type="nucleotide sequence ID" value="XM_047910183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF32"/>
    <dbReference type="GeneID" id="71990913"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11035"/>
    <dbReference type="OrthoDB" id="5397846at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="40"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="24416" checksum="1C7F1609C5188CD1" modified="2023-09-13" version="1">MATTSSLPELHDLRRSLLATLEQVDRAIAGSPPAPPCHLRRLPLELREKIYALAMFPQPQGQRLLAINEAHPELADTTVTDHHGYEVSSYNAERYHPPPLLQVCRQIRAEASKVFYSKVIFWKHSSCSSAQIDISFFRGFLRRLATENRELVKNIRLERVEFLGNTPKPFSLSEARDAFLQRPEYIGDQLEFACKDDGVRGGWRYQKARDLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH44</accession>
    <name>A0A9Q8PH44_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
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        </location>
    </feature>
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        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="37648" checksum="13B3C8D43BFB11AB" modified="2023-09-13" version="1">MEFLQHPATLYCEEVVAWINPCVGVVAFVEASTYGTPHSYIKDKWFDMHYSLPQVLTDIQVDSQAVEHYNNVLLSGTEYTYERQRYERTVSEVENHILRDLLVDVALQRYQKANRYTVSLTILEKVMLGEYGWLPAGSPLHLPDLPIVTIVDDVSYMARRGDTEPLQENFVAIKNLPRHLQKWQLLEFMAKQGLPMPIRLTCLHKDEWFIGVAFADYHDSEIAAEAMTSMNQLTIDGREVMAEPKTMQSRMHRNLVYRHERHHRVWSGETSSTERETESLKASTSTADADASSQITDQNSVVADMEAGAESIASGSDEYHSCSEWPSAEQ</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Stergiopoulos I."/>
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    </dbReference>
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    </dbReference>
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            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHN5</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
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            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="22014" checksum="C7582E8AC8CD022D" modified="2023-09-13" version="1">MGVNVNHEYIASATKAAKQAGLTNVSFHIGEISALATMPANSSDIAHAYQVLLHLITPLSALKELHRLLRPGGFLAIRDTADAFHVAERPTMTVYRETTVKLNPQLLQARRTTQVWVHEAGFPLDRIQAGCAGWGFSGREGRRMWAGGMVESARRYGPMMGFEDETFFDLSERKFGEWAEDERARYMAMDGWVVAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHX5</accession>
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    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767330.1">
        <property type="nucleotide sequence ID" value="XM_047911380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHX5"/>
    <dbReference type="GeneID" id="71992110"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12232"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="42"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="44225" checksum="82B44233C2977134" modified="2023-09-13" version="1">MPYSTKAMKKLEHRSLITAPNNLTYSYYLSPNFSQKLSKDVPTLMFVHGYPDDAYMWAGAIPTFLEMPYPFLVLDLLGFGHSSKPVETKNYNYKAMADSISQILDKEKVPNSVIPIGHDWGSATSQRFYLYHKSRCIGLSLLSLAYQVPSPTAFDLATANADTTKRFGYPQWEYWNFFTAPNAAELMRHNMERFFEVNHGNFPSPNKETDNSPKSGPLATKGDEPGRDIWMREMFDTGDGTVEGNAMYQYVTQTGAWKGRIVELKEYAKNDPSIFERFRERMSRDGFEGPVQYYHSLKNNTMLEDERALCEKEENKKIEVPLLYIGQTGDWVCRVDLMGDAVQQGLVGDLEERVVDAGHWCLYEKPEEIAANIKEWLERRFPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIH4</accession>
    <name>A0A9Q8PIH4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767395.1">
        <property type="nucleotide sequence ID" value="XM_047911634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIH4"/>
    <dbReference type="GeneID" id="71992364"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12486"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="318" mass="36626" checksum="DBE75E51A67D9FCB" modified="2023-09-13" version="1">MADNHYHWLWEPIRNIIEMHDKKRSKKGDNRVFTTFTMSVFIFREGRLLLLQPTDTPGWTVPSRSVRRLDNEGRGCEGLVLQMFYDAIRTKTLDHIQFIDLAIPDATKSIAEISATELHMNVLLSVPEDLSLDGDSLPYLPGQWQDLQWADHATAVSLEIENPKRERLRAAFHQYTAIANAHRRFAQGHDATQLYATAYNSCKLARELKNVWYGGARVDHILVAVKTREPEAGLFLIWKIDDILAKKFHDGTYTKVVVALGYEGGQYPEERMNLVGEFQRGSGILRQNIGLHLMLEEEVRLKISWRTWSRTLYFKGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIL7</accession>
    <name>A0A9Q8PIL7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein ORM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767592.1">
        <property type="nucleotide sequence ID" value="XM_047910943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIL7"/>
    <dbReference type="GeneID" id="71991673"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11795"/>
    <dbReference type="OMA" id="STHYTHF"/>
    <dbReference type="OrthoDB" id="1932233at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26627" checksum="CF8A038E7D8C7753" modified="2023-09-13" version="1">MVIFLPSHRPRSASSTSNNTAKLSSTLLQRGGISFADTSPPLCVQSAERKMSNNFKENRRRRRSSSLMYQEPPESLEQQSDQAVLPNLNAQWVNAKGAWMIHAIIIVLLKIVYDVIPSISQETSWTLVNITYMCGSYLMFHYVRGIPFEFNAGAYDNLNMWEQIDNEEQYTPAKKFLLSVPICLFLISTHYTHYDLTYFTINLLATLAVVIPKLPAFHRMRFALFNPEPLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJG1</accession>
    <name>A0A9Q8PJG1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767860.1">
        <property type="nucleotide sequence ID" value="XM_047911691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJG1"/>
    <dbReference type="GeneID" id="71992421"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12543"/>
    <dbReference type="OrthoDB" id="3649243at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="96"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="33186" checksum="DE678F53ADC6024D" modified="2023-09-13" version="1">MYPHPYRSGGLREGDNPSRIIQRRPPLQMAGNIGYVPIPPYPPQATSDRMLLDPLFLLQAPYGGQTANTHATATPSKKPDGADRLAADKAIDATERTISVIVGTSPDRKTFHVHASVLQRSSEYMRSKAKPEWSRGSATVDLSHQDATAFNIYINWLYQSQIVSATDENPRTEWMGLVRAFALGEELIDQAFKNAVMSALSATAHESQVEDVLPFLVEMVLIIYDATPEKSPARFFLVDVGKSVEKEQLRKLRGELPHDFIFDLAVAQATHDTPTRIGDKRKFQSISTVAHNVQAYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK59</accession>
    <name>A0A9Q8PK59_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768319.1">
        <property type="nucleotide sequence ID" value="XM_047911872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK59"/>
    <dbReference type="GeneID" id="71992602"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12724"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040411175" description="RRM domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="321"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="48653" checksum="8A3E460381123D9E" modified="2023-09-13" version="1">MSMHGLFMSWLAICRIVCQLCDAFINTPLLLLSDSSHASSRGLTALITSFFLEVLPPSPSFIRPTPHSHLHTCWCGLFDNHIWRLCGFSMSSSRGNGPFFVHIENLPDRYTWQDLKDMIRRRAAHGVWTDMAVLPNGQPGGKGYARIQRSNEASDLYKYLTQNIIEGRRLRVHLWDTSEIPANFITCNCNNTQIHPSGQQIAQWVAQPGWQTFSATSPISMAQPALYPPPSTMPTMMPPSVQQPPMQWSADQLTLAMSRVGLDPRNPADVHQYTRQVWSVRQAPQQQYQAQGGAQQYPRYMANSTGLPTNTSQGVIRTEARGIFISGLNFKACTRDIELHFGEAGEVVKVDLQKDPQGKSKGNATIQYASAEAAQRAIEMFHGERFQNMRMNVRRDKEATAINAPQPTGTVQSAARRTEQPTIVNGSQVRQAMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKL2</accession>
    <name>A0A9Q8PKL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquitin conjugation factor E4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13441</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768740.1">
        <property type="nucleotide sequence ID" value="XM_047912589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKL2"/>
    <dbReference type="GeneID" id="71993319"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13441"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="993"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="541"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO24374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1075" mass="122070" checksum="4DAE531E15247FCD" modified="2023-09-13" version="1">MADSTQSDADKIRAKRLAKLGGPASSSTTTPPAPAAENEQPAPATAPQASDATAESDPAIASQRANYFAQMPAKAPEPKSTTPQITVKPAPRPASPAKRERDGSEKAQSRTVSRSERPPESIEKWQDRNLRQIYRVTLKPEEVTDGHGNKLIFLSNTKEELEEADSPLMLDVNGSDGILSEAAGQAPGGKVFEYFLQCFKRVSRAIRGSKYDGPDDPKHGILKEARRFCMSYCIFAVTMPDMFENNASTSNPLVAHLKADPECEVGICTDFLNEATSRFEEDDSIKEAVVGAAEELSRQLAKQDMLGDYQNYVRGLRNLLRYPKIVDAVTESPLWAPGDVAAQEIETKTILGPFFRISPAQQDVANSYFSAPRTRDSGFVRNGQNAIRMTLRTHQHELFEITNSIVKSGPVSRGRILDWLAICVNKNHKKRAMRPDPRIISTDGFMINVTNVLDQLCDPFMDARFGKIEKIDVAYLRRNPRVDISDETKINADQKAADEFYADKVDGTNNFISEVFFLTVAAHHYGTEAAQEQIGPMRKTIKRGEEELKAMEAERHKYVNDPRYLAKYEESLQRYKNHLDNMASRIHATEGILLDDLNQARSMQFMRYVIVWLLRLATGQNLPTAQLQLPLPETQADVFRFLPEYFLEDIVDNFKFITRHMPNIITPQQSEELVQVCITFLRSTEYVKNPGVKSGLVTILFTGVYPWGHNRRGILGDQLIGSSFAHKHLLHALMKFYIEAENTGTHTQFYDKFNIRFEIFQVIKCIWVNTIYRENLAKEARVNTEFFVRFVNMIVNDVNFVLDESLGSLRKINELTKELADPVHMQGLSEEQRKEKQELLDDQKGKARSYMGLTTESMETLVLFTETLPDSFTAKEIVTRLVDMLDYNLMTLVGPKSKDLKVDNMQEEYKFNPRQLLSDFITVYVNLGEKQNFIEAIADDDRSYKPEHFDKAANIMKDKAMKSPEELRAWERLGKKIAEVKQAKADEEEDLGEIPEEFLDPLIGDLLTDPVYLPTSRTTVNRSTIRQQLLNVPEDPFNRMHLTMDQVVAVPEVLEKIEKWKAERRAEKAEKMDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL23</accession>
    <name>A0A9Q8PL23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768761.1">
        <property type="nucleotide sequence ID" value="XM_047913163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL23"/>
    <dbReference type="GeneID" id="71993893"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14015"/>
    <dbReference type="OrthoDB" id="5335812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053267">
        <property type="entry name" value="Verrucosidin_biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087:SF1">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="31845" checksum="C388F81831C2C300" modified="2023-09-13" version="1">MGSMPYNHFNSISYLPDGLYPRGNGTSRERQEGSRRFVDSAMDGEPAPPSMDSSNFDVLEWHPAYQSCQRFFVDHAQFEPATQAVCALINIRLPFQWLTTPITSSGTPPSTSRGPQTSSNFDFNAFSRQQREGGRSPYGQRGPDAPPTFVSPIPYIRRLVVTGFDKPAILHGFFGDEYVKGAMPHVECERRNYLFAAKHGGWRSCKKQYDNGSGGGGDETVPFMKPLDEAKMEELTAAEKAWSSWLAMEDWMVGPRAPEDDEAPRMHSNRPGYPHVRDGGGMPDGI</sequence>
</entry>
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    <accession>A0A9Q8PLH0</accession>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PLH0"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="273" mass="30388" checksum="E8D4E7963E50CE11" modified="2023-09-13" version="1">MAIPHVLNRSRNADPARNSDAAAQHGTASGGTRDRQSALLALSRELRDIVYHSLLNERKRPPEDPHHANDRTPTSQSSPGAIYYETQSPKPALLQLKLCCRQVSAEVQDLLAKHVVSHSGPGQLDIMVRGSSVWPTWIALPLASKLDPIIDIELRIFDTTGLGSEFSTGAYRALWSLFNRMVFRGPCLTHSRNLQRPLIVGRLRFNIVLCFPTSVDDLLGTYRDVFDRLERLAYDNVGLGNVGTIEACLGADRRVWRLKQLPTGLTFASRQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLQ8</accession>
    <name>A0A9Q8PLQ8_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="7" type="ORF">CLAFUR5_14560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO24929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLQ8"/>
    <dbReference type="GeneID" id="71994438"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14560"/>
    <dbReference type="OrthoDB" id="10514120at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="274"/>
        </location>
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            <begin position="21"/>
            <end position="182"/>
        </location>
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            <begin position="194"/>
            <end position="220"/>
        </location>
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            <begin position="61"/>
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            <begin position="88"/>
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        </location>
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        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="313" mass="34148" checksum="D008A85A7CC98EA8" modified="2023-09-13" version="1">MPRLTEEDLIGPVEEAAELQSMLGGDLTPRDQLITPPEQPPLAFGVAEFTSQTGEGVPETYVTSTTSAPSANHDADQAPEQPLEDAATTPNSSTSTSQHQDPTTGTSIATSITTSTPSTPSTPKRSKASKRKSTTTTSSPRPRSAAKRKSRNFEDDDDEYRAPSTPRSKARRSRVVAKADDDEEYGPARFVTRTMTRKITRGSRYGSRSSDPDPDQEDPADEISLCLADCQRAEDDEMLECAGGCEKKFHAPCVGFRSVLPVGRRWLCFECRKEKQLGMRSNGIVAEGEEGELVEVAAGSKMEIEWKRDGRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMV4</accession>
    <name>A0A9Q8PMV4_PASFU</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="32"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="29681" checksum="157C7DD02FFAA8A9" modified="2023-09-13" version="1">MLIQESHKDVPTQHGGDMRIFIFHPTIPNYPKAKFPGVVIFSEIYQVTGPVARFARQIASHGYIVAAPSSYHEFTGPEPLAYDGPGTDKGNAWKIEKKVSAYDEDATLSIDLLVGLDTCNGRIGATGMCLGGHLAFRAAFDKRVLASVCYFATDIHSKTLGEGKKDDSLERAARGDIKGETIMIFGKRDTHVPPAGRDLIRKTLHEAGTTFSFYEPAWAQHAFIRDELSKGRYDPAVAGICFQMLLELFGRTLSGDLGPRVNDSGEVEDVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQA8</accession>
    <name>A0A9Q8UQA8_PASFU</name>
    <protein>
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    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UQA8"/>
    <dbReference type="GeneID" id="71987321"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07443"/>
    <dbReference type="OrthoDB" id="727118at2759"/>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013258">
        <property type="entry name" value="Striatin_N"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08232">
        <property type="entry name" value="Striatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Striatin N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="751"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="575"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="830" mass="89834" checksum="7BAEAEC8D5629006" modified="2023-09-13" version="1">MAFQQQAGLGNGAGGGNGEHHGPQGTEYTLQGVMRFLQIEWHNHERARNAWDIERAEMRAKIAKQEGENKQGKRINEQLERQVRMLEMALKNERAKSKGANGVASTTEQKAGGAEAQHDVKSKQGADEAKNGENKAKPPYVPHNSFLDTAEQETSDREREQYLNNTTKYLKNCMKEIQYLLTPPQHPPPPQMLPNGNYSGLPEPPLVEDIYARQQPRSQRHQGLPQQQAMPNHQPPPVPNSLPQVQDGGQRDLRYAEYQNSQQQPTEILQSSGQHIPAPYEEQVENVTHTFDNRGRPVLEQEQEQVRPVRQQADTDGWTFDEETPMHPDNPPPDAPPPRRPDTDLFPSAASVTALPAKSPPRTAANPRRRKSSGAKSMERRKSSQGRNEGHESIANAMSEDPTQFKVKFALRGHLDVVRSVIFSGGGSPSEPEVCTAGDDGTIKRWIVPATYQNFTPGNNSSDLDISAYFTHRGHDGTVTSLAAPPASTGFSTGGRNNGEGWIFSGGQDHNICVWERGRVDPKAVIEGHTDAVWAVCVLPASVGVVFGPHSGNFGGPDRLLLVSGSSDGTVKVWAVSSPPQSSSPATGSRRGVGGSRRHSVTSGSNYPTSPQPSVASPTPFSYTLVHSIERPGDNKVSPTSICPLSASGENFVVSYADSTALIYDTRTGEEVIGMASNETYDGTMNTSINAVVAASTAMESNDATRGMEAEEVGGGATGSREGIEGVVITGHEDRFIRFFDANSGQCTYNMVAHSGAISALSLSKDGREAVSAGHDASIRFWSLEKRICTQDIISHRAMRGEGVCDICWSSDGRLVVSAGGDGVVKVFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URT7</accession>
    <name>A0A9Q8URT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase aflX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URT7"/>
    <dbReference type="GeneID" id="71990005"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10127"/>
    <dbReference type="OMA" id="GCTIAQD"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="8"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="27920" checksum="46F01DADE7A551D5" modified="2023-09-13" version="1">MPSYAILGATGNIGRSILEVLLQSPDNHINAYCRFKQKLYKLMPVVKHNKQVDVFEGELSDINLLARCLIGTTAAFQAVAVDGNQPGCTIAQDTSRRVTTALEHLKANGHRLPKLVVTSSSSTDHSLLSNVPSFFRNMLYRAFSHTYDDLLAAEKFIRSKDDLISATFVKPGALTSQPQVGHELSLEVAKSPLSYLDLAAGMIELADDSSERYDMKGVAVNSAVKVPFPRESPMKIFKGLLCHFFPWLYPYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI7</accession>
    <name>A0A9Q8USI7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765181.1">
        <property type="nucleotide sequence ID" value="XM_047910078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USI7"/>
    <dbReference type="GeneID" id="71990808"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10930"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18230" checksum="C63CCCF779FA9FF4" modified="2023-09-13" version="1">MEHSKWIVWAQSPDWQRIFAPELEQGTGSSELLGRLSEDPALVATSALISTGHILTIRHSRMSPLIARCIWELRSFVTRTINEALRDPERGTCDALIGAVLILAKHEGLQGKADSYHIHMRGLVQMINLRGGLVSLNRRQKYLESMVNWQDANVSAVMGNTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USX5</accession>
    <name>A0A9Q8USX5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11175</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765603.1">
        <property type="nucleotide sequence ID" value="XM_047910323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USX5"/>
    <dbReference type="GeneID" id="71991053"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11175"/>
    <dbReference type="OMA" id="RGPNDYQ"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000009">
        <property type="entry name" value="T-complex protein 1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000070">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO21237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="588" mass="63440" checksum="BF9922DC49644E28" modified="2023-09-13" version="1">MAGIFEQPRNQGTLFLGGQKISGADIRDQNVLATQAIANIVKSSFGPSGLDKMMVDDIGDVTVTNDGATILSLLNVEHPAGKILVDLAQQQDKEVGDGTTSVVLIAAELLRRANELVKMRIHPTTIITGYRLALREAVRYMNDNVSTKVETLGRDSLISIAKTSMSSKIIGADSDFFANMVVDAITSVKTTNARGEVKYPVKAVNVLKSHGKSATESMLVKGYALNCTVASQAMKTRITDAKIAILDMNLQKERMKMGVNVVIDDPAQLEKIRERESSMVIERVEMILKAGANVIFTTKGIDDLCLKHFIEKGAMAVRRCKKEDLRRIEKATGATMISTLADINTGDDYFDPKALGEAKEVVQERISDDECILVKGPKVHTAASIILRGPNEYSLDEMERSVHDSLSAVKRTLESGRIVPGGGAVETALHIYLEEWATSVGSREQLAIGAFAQSLLVVPTTLAVNAAKDSSELVAQLRSRHALSQRTSEPASAHPPAQANGAPAPQATKTQQALDADAKALAKAKGYKNYGLDLSKGKVQDCVKAGILEPSMSKVKQLKSAVEACVAIMRIDTLIKLDPEQRGEPDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT86</accession>
    <name>A0A9Q8UT86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765886.1">
        <property type="nucleotide sequence ID" value="XM_047908698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT86"/>
    <dbReference type="GeneID" id="71989428"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09550"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="627" mass="71471" checksum="99D1BE3B264DAC72" modified="2023-09-13" version="1">MLSFIVLALAGLLVLYLGNTYRCFRINLALAKRSGLPYIAMPIYTFNRFWLVTHALWLPWIQRLPKSWTQDWIDFLQPDFVWTQKHRLFKEIGSDVLLLVAPGSNTLYVADAEAVTQITARRNDFPKPTWMYSSVDIFGKSVVSTEGALWRHHRKITSPPFTEKNNYLVWTESLQQAESMMAGWISKDANDSGALWNVATESMRLSLHVISRAGFGVHLHWPHEDKDTPIPEGHTMTYKDALESLLHNMIVMILTPTWLLSRSPLKFHKTAHRAFSEWGQYMREMYQEKRNEVKSGQSREGMDLMGALVKGAGMTEESLNEKATTDPEKGGAGKGLLSDEEIFGNAFVFILAGHETAANTIHFSILYLAMKMTSQRRLQEDLDAILGDRPVSEWDYEKDMPKLFGSMCGAVMNEELRLIPPVVGIPKTTPNDRPQGLQVNGKHVTVPENCYVTLDTVATHRNPKYWPHTSEEDLLEFRPERWLLDPSKTNANTEDSTYAEEEGLDFDGPDKRPDTAASLFRPAKGAYVPFSEGYRSCLGRRFAQVEILAVLAVIFKTHTVELDVSEYLSDEEFKTATEAQKLEAWKKADARARELLENGMMTIITIQMRKGKVPFRFVKRGCERFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTH0</accession>
    <name>A0A9Q8UTH0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-224 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766305.1">
        <property type="nucleotide sequence ID" value="XM_047908843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTH0"/>
    <dbReference type="GeneID" id="71989573"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09695"/>
    <dbReference type="OMA" id="MFPRIVV"/>
    <dbReference type="OrthoDB" id="410463at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160205">
        <property type="term" value="F:cysteine-dependent adenosine diphosphate thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="35799" checksum="F53DE10AFD41893F" modified="2023-09-13" version="1">MSPPAMMYEQPASNGHSVPVAASKLAGLPHNTAIPVGGHTKPQTVDEMAGNWSDFKFAHIRESQVSRAMTRRYFADLDNYAESDIVIVGAGSCGLSTAYCLAKARPDLKIAIIEAGVAPGGGAWLGGQLFSAMVMRKPADAFLREIGVPYEDDGADSNFVVVKHAALFTSTVLSKVLQFPNVKLFNATAVEDLITRTDGQGNIRIAGVVTNWTLVSMHHDDQSCMDPNTINAPVIISTTGHDGPFGAFSVKRLVSMGSIPALGGMRGLDMNVAEDAIVKGTREIAPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEALKIFDQRKAECAESGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTL0</accession>
    <name>A0A9Q8UTL0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein SEC24</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein transport protein sec24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_08827</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766410.1">
        <property type="nucleotide sequence ID" value="XM_047907975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTL0"/>
    <dbReference type="GeneID" id="71988705"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08827"/>
    <dbReference type="OMA" id="AVECSKQ"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="18">
        <location>
            <begin position="274"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="19">
        <location>
            <begin position="348"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="21">
        <location>
            <begin position="595"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="20">
        <location>
            <begin position="689"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="17">
        <location>
            <begin position="819"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO22044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="954" mass="103773" checksum="8613C24C64F41E11" modified="2023-09-13" version="1">MANPYQQDAGPDPEGGSPYPQDGGAYDQQPAAGAAPKKKRDRYAGQAYEFGAGGNAAAAPPGGGPYPGQQPVAAQAPQNIQGGYGYPGQGAQPAYGMPQQPSYGDPAMGSPAPQQVPYGQPQYGAQGGYEAPAPGYPTPAQPGMPPAGVQGMTQQFGQMGMGGGQPAPQPQQQQGVQMRLNPLQPVDISPQGQPFHVSDLDQPPPPIILPPNSSVTPSPHANCSPKYVRSTLNAMPATASLLKKSKLPFALIIQPYATLHDSEDDVPVQSDQVIARCRRCRTYMNPFASFLDHSHRWRCNMCNLTNDVPQSFDWDSVKQQSVDRWQRPELNYAVSEFVAPQEYMVRAPQPLIYLFLFDVSYAGVTSGLLATAARCILESLDRIPNTDRRTRLGFMAVDSSLHYFSIPRDGGENNDAKMLVVSDLDEPFLPTPEDLLVNLTECRANIEAFLEKLQGMFANPQNPSSAMGAALRAGHKLISHVGGKMVVLSATLPNTGFGKLDMREDKKLLGTSKENALLQTQNSFYKSFAVECSKTQVSIDMFLFSAQYQDVASLSNLPRYTGGQTYFYPAWNAARTEDAIKFATEFSDYLSSEIGLEAVLRVRTTTGLRPSAFYGNFFNRSSDLCAFPSMPRDQAYVVEIAIDESITKAFACLQVGVLHTTCNGERRIRVMTLSIPVTQNMADVYAGADQQAITHYFAHKAVERALSSGLDAARDALQAKMVELLQTYKKELGGGNMGGGGLQFPANMRALPMLFLGLMKNLGLRKSAQIPTDLRSAALCLLSTLPLPLLMQYIYPRLYSLHDMPDDAGLPDAETGAIVMPPALNLTSGNIAPYGLYLIDDGQTQFLWLGRDAVPALINDVFGTEDKNQLKQGKTTIPVLETEMNERVRAVVEKSRDHRGKGCGSIVVPPLYLIREDGEPSLRLWAQTMLVEDRADQGESGAMFIGKLREKVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTY2</accession>
    <name>A0A9Q8UTY2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">7, 8-dihydropterin-6-methyl-4-(Beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766664.1">
        <property type="nucleotide sequence ID" value="XM_047907960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTY2"/>
    <dbReference type="GeneID" id="71988690"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08812"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052926">
        <property type="entry name" value="Metallo-beta-lactamase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13754:SF13">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G07630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38148" checksum="511104F8369FD85C" modified="2023-09-13" version="1">MVHTSLTMHPLDLVELDSLEILVIIDNELDPISPCPNPSVVQTGSLRDIAIASEPPSSPRAEAIREFRMDSICCSAHGLSLMITGTKGDTMRTILFDTGPEEAAFERNAKRLKADLAKIEMIRLSHWHRAHSGGMLQVLRMIDEARAGHQSQLPPVSVDLHPDRPMYSGIKVPDVPPFSMEADPTFEEIEQVGGKVVKSDQPHTVLDDMFLVSGEIPRVTEYERGLKFGTRLRSLEKGWEDDSLMKDERLLMCKVKEKGIVMFTGCSHAGVVNASRHAAELGQGTPLWAVMGGYHLADGEPELVQKTVSDLKALDVQVMLAGHCTGWRAKFEIQNQMPGRQCHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU41</accession>
    <name>A0A9Q8UU41_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766788.1">
        <property type="nucleotide sequence ID" value="XM_047908548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU41"/>
    <dbReference type="GeneID" id="71989278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09400"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="33144" checksum="D009B889334B04E5" modified="2023-09-13" version="1">MKLNFKSRLRHVCKRRPQPRSTTQYQTQPSCAFLQLPAEIRNDIYKLVLVTTDSISLHLNNLPQPALTTACRQIQAEALPIFTWNNTFVLNWTMSNRGILRSSTNPGTLSWTKRTSAIAFFQTIEFRSRTTAKLFSQTPLHSFMIKLPLPGEDEVLSFHHREYCPDTNTHNFSDCRYYQKTLNSSAESLNKVTTDHRAQGVAGLIEIGHAMPKVLAGRGDRVWWSVLGLTALNRIGASDKIWCSWVLLYEDSDEEEEEEEDDDVDDENREPEIARQLMEYSSTMVLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUB1</accession>
    <name>A0A9Q8UUB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767130.1">
        <property type="nucleotide sequence ID" value="XM_047911471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUB1"/>
    <dbReference type="GeneID" id="71992201"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12323"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="16994" checksum="AAB96479FD9E52B8" modified="2023-09-13" version="1">MQPFAEQFVAHLDTLSPIEIEQTIEAVRAGHEQTRKEARNINTKRFKESASLNAATGSQSHDASIVGDGEDVVFRADDIERGLVDRAELPSAYTAARRSVSNSWRSIGGEPYFKHKMSEAEERSTTVDYADHSPFSQWLPLFGVGVKLLRSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUK8</accession>
    <name>A0A9Q8UUK8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767268.1">
        <property type="nucleotide sequence ID" value="XM_047911142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUK8"/>
    <dbReference type="GeneID" id="71991872"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11994"/>
    <dbReference type="OMA" id="VFEGHAY"/>
    <dbReference type="OrthoDB" id="3645319at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17692" checksum="C7428ED372CF9359" modified="2023-09-13" version="1">MDPPPTPDHPSNQLNSLQKMNSETLRLVYEHKANGRNMVPDGICFMSDYDLVLILSQRKYHVPKSSVHRLTSLQMRTSVWEAKKIKPGSTTIEIWKADLMTEKEKVAAAKVQKSKDESEEVAWPVFLGYAFEGHCLEELTILVPEVVAKGGKEAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVI6</accession>
    <name>A0A9Q8UVI6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768288.1">
        <property type="nucleotide sequence ID" value="XM_047912102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVI6"/>
    <dbReference type="GeneID" id="71992832"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12954"/>
    <dbReference type="OrthoDB" id="10569179at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040178121" evidence="1">
        <location>
            <begin position="17"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="27921" checksum="BF56DDE16E07DA40" modified="2023-09-13" version="1">MKYLTSSLLLLAVVSAAPLKDMHDQDISNHSPAAAAFRKTFRTFIRRTDADVDKFMLKAQRTTDEFIEAATTWKRNAQEATEEATAAIAVSNRSLQLRKVIEEEDVDAFLNREYARAEASSKHAKRLSREANEAATLAATSEPHPLSLASFASGLRRSADAASEEAQEAFDTVAYDLKVRAEDESIDQIVERDQSAAELATVKETRAKRELYFAEKDLKKRVAFFEKEKKLRAEFPATASVDEKMGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVV9</accession>
    <name>A0A9Q8UVV9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768765.1">
        <property type="nucleotide sequence ID" value="XM_047912938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVV9"/>
    <dbReference type="GeneID" id="71993668"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13790"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13143" checksum="BD4A74C5A9886403" modified="2023-09-13" version="1">MLKLERIGGSARGHIEHTTQTSRQAKHTTPHHQQHTTPHHTTPHHTTPHHNMASMKLKLIHLRHRLRLLCCFGVREDDLVAPMGTDPRVRGKLAKHYRDNGITSPPPPTLKGGSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY0</accession>
    <name>A0A9Q8UVY0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Citrate synthase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY0"/>
    <dbReference type="GeneID" id="71993669"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13791"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005759">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12234" checksum="6B16B6066AB8F2C1" modified="2023-09-13" version="1">MYSVDTAVEGPSPSSSPSPQSFYNQAHRTTAELIDRCPSDLHPMAQLSIAVNALEHKSAFSKAYAKGIKKTEYWEHTFEDSMGLTTVPSVVGWLRALAGVRQTVLLLLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW30</accession>
    <name>A0A9Q8UW30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768975.1">
        <property type="nucleotide sequence ID" value="XM_047912562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW30"/>
    <dbReference type="GeneID" id="71993292"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13414"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="31040" checksum="A98177588E77BB03" modified="2023-09-13" version="1">MAAQCTSQRRHEWDRSPPRDLCMLPTDYGERCICKRCFHMLKRSLTGVSREPRAALALFTSGTKASLFLKLTLFLFSPNNADSRHPQTTAASHSQQSTTINAIRQTNTNTAIMRFLLKIMMALMAMITVSAALPAADNAASTLSTVITSNAADIFAVPSTNDTLLHATRDPPCNDDVATICTECMSCTAKDSGIAIEYFVHTGWEIDYDRCQRVLDCMNEDHFANSITHWHCEADCRSGTYLHFNSIFHQQGRINWCFDDTWPEIEGDRDAFNCPSH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-06-18" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>O94203</accession>
    <name>HCF5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Class II hydrophobin 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hcf-5</name>
        <name type="ORF">CLAFUR5_11007</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1999" name="Mol. Gen. Genet." volume="261" first="644" last="652">
            <title>Isolation and characterisation of five different hydrophobin-encoding cDNAs from the fungal tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Segers G.C."/>
                <person name="Hamada W."/>
                <person name="Oliver R.P."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="10394901"/>
            <dbReference type="DOI" id="10.1007/s004380050007"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [MRNA]</scope>
        <scope>INDUCTION</scope>
        <scope>TISSUE SPECIFICITY</scope>
        <source>
            <strain>Race 4</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2001" name="Microbiol. Res." volume="156" first="1" last="5">
            <title>HCf-6, a novel class II hydrophobin from Cladosporium fulvum.</title>
            <authorList>
                <person name="Nielsen P.S."/>
                <person name="Clark A.J."/>
                <person name="Oliver R.P."/>
                <person name="Huber M."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="11372645"/>
            <dbReference type="DOI" id="10.1078/0944-5013-00069"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>INDUCTION</scope>
        <source>
            <strain>Race 4</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2008" name="FEMS Microbiol. Lett." volume="286" first="136" last="144">
            <title>Localization of Cladosporium fulvum hydrophobins reveals a role for HCf-6 in adhesion.</title>
            <authorList>
                <person name="Lacroix H."/>
                <person name="Whiteford J.R."/>
                <person name="Spanu P.D."/>
            </authorList>
            <dbReference type="PubMed" id="18958901"/>
            <dbReference type="DOI" id="10.1111/j.1574-6968.2008.01227.x"/>
        </citation>
        <scope>TISSUE SPECIFICITY</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Aerial growth, conidiation, and dispersal of filamentous fungi in the environment rely upon a capability of their secreting small amphipathic proteins called hydrophobins (HPBs) with low sequence identity. Class I can self-assemble into an outermost layer of rodlet bundles on aerial cell surfaces, conferring cellular hydrophobicity that supports fungal growth, development and dispersal; whereas Class II form highly ordered films at water-air interfaces through intermolecular interactions but contribute nothing to the rodlet structure.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer. Further self-assembles to form highly ordered films at water-air interfaces through intermolecular interactions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Secreted</location>
            <location evidence="9">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="tissue specificity">
        <text evidence="4 6">Only appears on young aerial hyphae (PubMed:18958901). HCf-5 is the most abundant transcript in sporulating mycelium (PubMed:10394901).</text>
    </comment>
    <comment type="induction">
        <text evidence="4 5">Expression is decreased during tomato plant infection (PubMed:10394901). Expression is up-regulated by nitrogen starvation, but down-regulated in the absence of carbon (PubMed:10394901, PubMed:11372654). Expression increases noticeably upon sporulation (PubMed:11372654).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ133703">
        <property type="protein sequence ID" value="CAB39312.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ251295">
        <property type="protein sequence ID" value="CAC27408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="O94203"/>
    <dbReference type="SMR" id="O94203"/>
    <dbReference type="OMA" id="MCCILPI"/>
    <dbReference type="OrthoDB" id="4500971at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd23508">
        <property type="entry name" value="hydrophobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF2">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0134">Cell wall</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000462444" description="Class II hydrophobin 5">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P52754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q04571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3"/>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="10394901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="11372654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="18958901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="7">
        <source>
            <dbReference type="PubMed" id="10394901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="8"/>
    <evidence type="ECO:0000305" key="9">
        <source>
            <dbReference type="PubMed" id="10394901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CAB39312.1"/>
        </source>
    </evidence>
    <sequence length="88" mass="8926" checksum="2D2A599C9500D383" modified="1999-05-01" version="1" precursor="true">MQFLVLALASLAAAAPSIKLRAPSDVCPALDTPLCCQADVLGVLDLTCEAPSDDTSVSNFEAACATTGLTARCCTLPLLGEALLCTTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-12-05" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>P0CU76</accession>
    <accession>A0A9Q8PKC6</accession>
    <name>CLAH_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Decarboxylase claH</fullName>
            <ecNumber evidence="1">4.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cladofulvin biosynthesis protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">claH</name>
        <name type="ORF">Clafu190728A0A9Q8PKC6</name>
    </gene>
    <organism>
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2016" name="Proc. Natl. Acad. Sci. U.S.A." volume="113" first="6851" last="6856">
            <title>Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Saccomanno B."/>
                <person name="Vaisberg A."/>
                <person name="De Wit P.J."/>
                <person name="Cox R."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27274078"/>
            <dbReference type="DOI" id="10.1073/pnas.1603528113"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2018" name="Mol. Plant Pathol." volume="19" first="369" last="380">
            <title>Down-regulation of cladofulvin biosynthesis is required for biotrophic growth of Cladosporium fulvum on tomato.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Overdijk E.J.R."/>
                <person name="Saccomanno B."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27997759"/>
            <dbReference type="DOI" id="10.1111/mpp.12527"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Decarboxylase involved in the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:27274078). The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG. The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078). This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078). The cytochrome monooxygenase P450 claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(3R)-atrochrysone 2-carboxylate + H(+) = (3R)-atrochrysone + CO2</text>
            <dbReference type="Rhea" id="RHEA:64264"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:234106"/>
            <dbReference type="ChEBI" id="CHEBI:234107"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:64265"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pigment biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="1 2">Expression is positively regulated by the transcriptional regulator wor1 (PubMed:27274078). Expression is down-regulated during biotrophic growth within tomato leaves (PubMed:27997759).</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Contrary to the other identified cladofulvin biosynthesis genes, claH is not locatilzed in the cladofulvin cluster, but is co-regulated with the cluster genes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768477.1">
        <property type="nucleotide sequence ID" value="XM_047912059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CU76"/>
    <dbReference type="SMR" id="P0CU76"/>
    <dbReference type="GeneID" id="71992789"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12911"/>
    <dbReference type="OMA" id="GIRRWTQ"/>
    <dbReference type="OrthoDB" id="3454835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000445896" description="Decarboxylase claH">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000269" key="1">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="27997759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="155" mass="17948" checksum="80926CF88CC71C26" modified="2026-01-28" version="2">MATATTTTATESPSNSGRRQARYLCLTILGYRKPGMSEEDYRNHMVNVSAPLTKDLMVKYGVKRWTQIHNQSETKALMSQLFDPQMCNLADYDCFSQVVFENIEDYKRMKQDPWYKKHLVGDHENFADTKRSQMTIGWVEEFVRDGQVVEGFKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXP7</accession>
    <name>A0A1P8YXP7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp54-1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 54-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp54-1</name>
        <name evidence="3" type="ORF">CLAFUR5_09955</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943107">
        <property type="protein sequence ID" value="AQA29278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXP7"/>
    <dbReference type="OMA" id="TCEAYEC"/>
    <dbReference type="OrthoDB" id="160054at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35396">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35396:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573453" evidence="1">
        <location>
            <begin position="19"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17287" checksum="E37BC3A477F427D5" modified="2017-04-12" version="1">MHSALLISLALAFTGTQATLKPCVNNAVGGIDPSDIPSDCQPCKSSPDIQAAECAWNTRCHSKDGTQTFAIFYRDTSKQNRLNVPLGLCVAYSDACNFQPTVDDLSDDSRDLQTFFWYEQSGGEDGQGTDCMRDFKSGQCKCENSDGSSIVGGVPFVDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4Q5</accession>
    <name>A0A9Q8L4Q5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755203.1">
        <property type="nucleotide sequence ID" value="XM_047900612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4Q5"/>
    <dbReference type="GeneID" id="71981342"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01464"/>
    <dbReference type="OrthoDB" id="4133832at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="43"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="27511" checksum="975F9FD6D9114127" modified="2023-09-13" version="1">MFSRDRMRENLAKARVTVRDGVKTCLRRNFTVRHKAREPEKTFALFLELPAEIRDRIYELCAENDRNILEEHFVSAKPPPELAIACASRQLRKEALPVFYRHYRFPVTFSSGDWINKGCLPPSMEWKAARWYHRLDPEKLRMIRRLELYYCFGRFQLDFDARSNGYEVRQTAWGSRRMVDVRPVEEKEQLLALVRSVVEDILQGPGVGMLTARDFDQLELEVLPDTVYQRKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4X4</accession>
    <name>A0A9Q8L4X4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Psi-producing oxygenase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755252.1">
        <property type="nucleotide sequence ID" value="XM_047901265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4X4"/>
    <dbReference type="GeneID" id="71981995"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02117"/>
    <dbReference type="OMA" id="EEPAHAF"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO10886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1084" mass="119430" checksum="EA5A0B1C902C05A6" modified="2023-09-13" version="1">MAPGIKSIIGHIKRKPSSAPDRKSGNEAASAPKVEKTSVLHDLTHLNMKDAKTLASALPALASGDPLDDKDLMLENGVAMLQSLPANSGLSAATSDAFIKMLYHDLPHPSTTMAGPTSKYRRHDGGNNNPWNPEMGKAGTPYARNVPPNKPKGPNLPDPELVFEQLMKRKGPFREHPSGLNRLFFSFATIVIHECFQTKRKEPWINETSSYVDLSTLYGNTEKEQVRVRTYNNGLIYPDSIASERIMLMPPGVVALLVLFSRNHNSIAESLLSINEEGKYKYKPWGELSKEEQVWQDNDIFQIARNINVGFFATVVLKDYVAAILNTPRANSTWSLDLGKEIKSAGQRVERGTGNVVSTEFAVLYHWHAALSAADDQWMEAVLRKHVPELKGLDQMTTKLFYERVMGAEAEHLNSLEPRQWTFGGLERDATGRFNDVQLGELIKDCVNEPAHAFGAHGTPESLKVVDILGQMQARNQFNVCTMNEFRSYLNLKAYGSFEEWNPDKETARAAELLYGHIDNLELYPGLMAECTKPAMPGSGVCPGQTTGRGILDDAVALVRGDRYLSYDFNSNTLSNWGVSKLGDIPGGTYGGMLPHLLFTGLPNSFTGTSPYALLPFYTPKAVKEILQDNKAIEKYDLVRPPPDGTVVGIHTRTGIKAVLEDANSFRPLSLPSVERLSTGREFMFGFHGSQSNKSTTLQKIFFEDGFEENVSKFFQTTTARLIQQCSLKYSSAKRSIDVVRDITNVAPIMWLANRFAIPLKTPETPKGLVTLPRLFDMYLALFLYSSFNVRAGREWKLRENAEYAVSTLGEIHEAHLKTQQGVKEHIVDWLAKGSAYEVGPDADRIYKALLATKQPIPELAGDCLGIGATVAGIITQQASLLIDLFLQPKYAESKKRIVQLAHLNDAASNKELQGFIFEGMRHASVVPGLPLVAKKDVVVQDGERGPVNVRADQKVLVAASKAAMDPLAFPNPEKLDPHRPFESYTLLGHGPGARVVGPAIAGMLKEVFKLIDLNRAAGRLGRFSFLEYKVGGAEIKHYLDANSSESPMPTTLTLEYYDNGALTNGLANGTTNGTAMANGTKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Z5</accession>
    <name>A0A9Q8L6Z5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-methylcitrate dehydratase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756318.1">
        <property type="nucleotide sequence ID" value="XM_047900253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Z5"/>
    <dbReference type="GeneID" id="71980983"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01105"/>
    <dbReference type="OrthoDB" id="10055203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047547">
        <property type="term" value="F:2-methylcitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.120:FF:000001">
        <property type="entry name" value="2-methylcitrate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012705">
        <property type="entry name" value="2Me_IsoCit_deHydtase_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006943">
        <property type="entry name" value="PRK09425.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02330">
        <property type="entry name" value="prpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF16">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="5">
        <location>
            <begin position="351"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="61311" checksum="6037C94A399575AF" modified="2023-09-13" version="1">MSTLAPRNLLRTSSRSLSRSTKAPLSASATLVQQSFRPHASRIARTPSARAFSAAMPARSNAPPSGPAPEYDPEIKDMAHYIHNYKIDSELAVDTARFVFLDTLGCGLKALEFPSCTKLLGPIVPGTTVPNGARVPGTPYVLSPIDAAFNIGAAIRWLDFNDCWLAAEWGHPSDNLGAILAVADWMNRTNKAGGQKINNGKTFTVLDVLEGMIKAHEIQGCLALENSFNKVGLDHVVNVKVASTAVVSQMLGLDEEQTRAAISQAWVDGQSLRTYRHSPNTMSRKSWAAGDACQRAVDMALKVSKGEGGLRTVLSTPTWGFYDVNFNGQKFKFQRPYGSYVMENVLFKVSYPAEFHSQTAVEAAERIHHQLKEMGKSAADIEEVTNRTHEACIRIIDKQHKPMENYADRDHCVQYMAATMLVFGRLTADDYTDGGEAASSELVESLRQRIACKEDPAFTEDYHNPEKRTISNALTVKLKDGTVLPEIVVEAPLGHRLRREEAKPEILAKYKRHIEPHFAADHVKKLVDLGNNPSELYKMQVDEYVDLYVKDKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7J9</accession>
    <name>A0A9Q8L7J9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lipid hydrolase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756716.1">
        <property type="nucleotide sequence ID" value="XM_047900292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7J9"/>
    <dbReference type="GeneID" id="71981022"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01144"/>
    <dbReference type="OMA" id="CSWFTRG"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="312"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="732"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="784"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="6">
        <location>
            <begin position="343"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="733"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="784"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="824" mass="93850" checksum="F73D0AAF698EA486" modified="2023-09-13" version="1">MSDTDKKTDGPPPSSASAFDYRALPDWDDDFYDEEGMIAFASALSAPENLAASPSEEDLLNPQSKKPPAELITALNDWRPVRQRQVRRHGDNRKSKVGKRKPRRGRDETREGWTYGLVKYPLLFFVFGWISFLGICYLFTRFYIYLYEQYVTWRGQRDRLRKRLRVQENYQDWIHAAKDLDRHLGNDNWKADDEGSYYDWKTLRSIVRNLRKLRAEAQKDEADSDHRNGRGGRRAIDELRATLETCVKANFAGIENPRLYSETYYGTKNLLQTYVDETAESLTFLFSSDQLTHADKRTLSKHLSANLGRTALCLSGGATFAYYHFGIAKAVLDAGLLPNVITGTSGGALVAALLGTRTDEELKKLLVPAVAFRITACHDPFRVWFWRWWRTGARFDSVDWAKRCAWFCRGSLTFREAYERTGRILNVSCVPSDPHSPTILANYLTAPDCVVWSAVLASAAVPGILNPVVLMRKTRDGKLEPYSFGHKWKDGSLRTDIPLKSLNLHFNVNFSIVSQVNPHVSLWFFSSRGTIGRPVTHRRGRGWRGGFLGSAIEQFIKLDLNKWLKVLRHLELLPRPLGQDWSEVFLQRFSGTVTIWPKTKVSDFWHILSDPSMQRLAGMIRAGQLAAWPKLKFISNRMAIEKVIEEAREATRPPEQPFASPMPREGGRLRSVLSEEDLQSLLDKARDNNGIVEVPPALFSPAVEREQLSWQRPLPQRQDSPSFAKRMSALWGTLQTDSPRTSSETVRPSPRQLVPPNTPADNRRSSVLTMDELVRQSRVFFDDYAEESEAASEVDTLLDESAEDEEEEEAEEGEGLVSERGRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7S3</accession>
    <name>A0A9Q8L7S3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756660.1">
        <property type="nucleotide sequence ID" value="XM_047899508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7S3"/>
    <dbReference type="GeneID" id="71980238"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00360"/>
    <dbReference type="OMA" id="TRFNKTH"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="202" mass="23313" checksum="C9F630C288E9A28E" modified="2023-09-13" version="1">MSTFEPVIVIDGKGHLLGRLASTVAKQLLNGQKIVVVRCEALNISGEFFRAKLKYQAFLRKQTRYNAMRGGPWHYRAPAKMFWRTVRGMIPHKTERGAKALERLKTFEGVPPPYDHKKRMVVPQALRVLRLKPGRKYCTVGRLGHEFGWKYQDVVARLEERRKVKGQAYYEKKRAARKSLAEAKEKAAIPDNVKQQLESFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8V8</accession>
    <name>A0A9Q8L8V8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="4">2.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diphthamide biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Diphtheria toxin resistance protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_01409</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757308.1">
        <property type="nucleotide sequence ID" value="XM_047900557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8V8"/>
    <dbReference type="GeneID" id="71981287"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01409"/>
    <dbReference type="OMA" id="PGQVLGC"/>
    <dbReference type="OrthoDB" id="1649088at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO12942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="463" mass="50952" checksum="790B58BE095C7D3C" modified="2023-09-13" version="1">MEEDRAIADLGPGVTPTTELDADAETVPKAPKRRFIGRKAADAIAAAKAESSSGTIEDSGAVQVAPRRRAPRALNNVPDDILHDKDINDAIALLPKNYNFEIHKTIHRVRTSGATKIALQMPEGLLLFATTISDILSQFCPGANTLIMGDVTYGACCIDDYTARALGCDMLVHYAHSCLVPVNVTKIQTLYVFVDIQIDVEHLLATIERNFKPGSTIAMVGTIQFNATLHGTSTQLRAAGYNMIVPQIMPLSKGEILGCTSPHLSKEQNVDLILYLGDGRFHLESAMIHNPSIPAYRYDPYSRRLTHETYDHEQLLSDRTTALTQARQAKKWGLILGSLGRQGNPHTMTLIENHLRERGIPWVNLLLSEIFPGKLAMMPDVDCWVQVACPRLSIDWGYAFPRPLLTPHEALIVLGGRKGWDEKVDENGGKAERVYPMDFYGREGLARVKANEVAVKQVVASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L971</accession>
    <name>A0A9Q8L971_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756884.1">
        <property type="nucleotide sequence ID" value="XM_047899298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L971"/>
    <dbReference type="GeneID" id="71980028"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00150"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="26786" checksum="D549A14D53B9C649" modified="2023-09-13" version="1">MDVIGTAVLSPPALCHTLSLHSLHLTCHAIAVNSGPRIRTGSDMRGVDIICAQGGEAGGHTGDIPSMVLLPACADICKQYTSPLTGKPVTLVAAGGINDGRSVAAALMLGASGVWVGTSFIPSVESKAPENWKKQIIEAGYDSLVKLTIWSGRPLRAMRNPYLDHWDKYRQAEIAELTSKGIVPLEYELDKLYKEGTLTDEIEESAALRPAGIVVGSVNKANQTAAQIVREMVTEAAESLSGAKNLANTAAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9D6</accession>
    <name>A0A9Q8L9D6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03542</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757706.1">
        <property type="nucleotide sequence ID" value="XM_047902690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9D6"/>
    <dbReference type="GeneID" id="71983420"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03542"/>
    <dbReference type="OMA" id="GNAWDCA"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:001190">
        <property type="entry name" value="Short-chain dehydrogenase/reductase SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="29768" checksum="D7EFC8A4801F76C3" modified="2023-09-13" version="1">MSEHFTRPTRSLAGRVAIVTGAGAAGEGIGNGRASAILLAEAGASVVCVDLDISLAQRTAEMIQTDGHGKVVAIKANVASEPDCKAVVEKAVSEYGRVDILVNGVGVGGATGTAVDVDMAAWAKSMEVNVGSMVMMAKYAIPEMRKNEGQQWRGSIVNLASVAGIRGGNPHLLYPTSKGAIVNMTRAMASHHAEEGIRVNCVCPGMVYTPMMYSSGMSEEARESRKNRSLLKTEGTAWDVGAAIRFLAGDEARWITGVILPVDAGATVATGSDVPSVNPEAAAQPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9F6</accession>
    <name>A0A9Q8L9F6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Siderophore iron transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_02873</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO13242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757608.1">
        <property type="nucleotide sequence ID" value="XM_047902021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9F6"/>
    <dbReference type="GeneID" id="71982751"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02873"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore-iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000197">
        <property type="entry name" value="Siderophore iron transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="57"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="611" mass="66525" checksum="D64987B08F78B669" modified="2023-09-13" version="1">MSGEKAYTSADQPYASSDEQRYAASPEPVVLTGDTSPGVKRIEALARHVTFNDRILLFITIFLLAYCYTLDGTLRYVYQPNATASYGTHSLLATITVVRAVIAAAAQPTAAKIADVFGRIELLLVSVVFYVVGTIVETFSNEVHTFAAGAVIYQIGFTCVTLQVEVIIADVTPLRSRLFFSFVPAAPYLINSWVSGNIAAAVLATSSWRWGVGMWAIIYPVMVLPVILVLFLAHRRAKKLEDMSNYKTPFQTYGPLQLLVALFWQLDVIGIILIIASLGLILVPFTLAGDGAQSWAQAHIIAPMVIGFLLAPVFVLWQAKSPHQMVPFKLLTDRGVWGPLGMACMLNFVWFLQGDYLYTVAIVAFDQSVLSATRITSLFNFCSVLCGIITGVVVFFVRRLKPFVLVGTVLYLVSFGLLIHFRGGSSSGNISGLIGAQVLLGIAGGLFPYVGQASIQAATKHEHVAIVTGLYLAVYNVGSSLGNAVSGAIWRQVLPGELQRNLGAVSTNATLATAVFGDPFTTAIEYPVGTPEREAIIESYRHTQRLLTITGLCLCVPLIGFALCLRNPRLTDTQSLPNAEEDRKTLVDREGRVVEPEKRSFGQKISDFFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9M3</accession>
    <name>A0A9Q8L9M3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757620.1">
        <property type="nucleotide sequence ID" value="XM_047901659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9M3"/>
    <dbReference type="GeneID" id="71982389"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02511"/>
    <dbReference type="OMA" id="GRTTKGW"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000298">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="104"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="194"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="38587" checksum="9F0DA8125F3B11A1" modified="2023-09-13" version="1">MTAQLPPNLLALFQPRPPLRYLPHHDFAPEERRTYAVDGIASFLPALKEKVEAEKDDVVTDSAMQAKENAKLEKQQKQKRLMEHDHKDLYKPAEDPNIRGDAFKTLFVGRLPYDAGTKDLERELGRFGPIERVRIVQDNGENSSKKGKSKGYAFVLFEKEKDMKTAYKDCEHLTIRGRRVLVDVERGRTVSGWRPRRFGGGLGGRHYTKSSMPKPSGYGPPPGPGGFSRGGGFRGGFDRGGFRGGRGGGGFRGDRGFGGRGGLGYQNGAPPDGAPAGPRGPGGGRGGGRGGYGGGGYDDRGGSRNANLEPLPPRGGGRYNDRDRDRDRDYNSGQKRPYEGGGYDDSRQRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB19</accession>
    <name>A0A9Q8LB19_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="10">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_03242</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="10"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757829.1">
        <property type="nucleotide sequence ID" value="XM_047902390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB19"/>
    <dbReference type="GeneID" id="71983120"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03242"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="55"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="359"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="559"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="376"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO13463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="609" mass="68663" checksum="1F3E8453A9120EC3" modified="2023-09-13" version="1">MSRVFACSRWRLLIDKALRPHLIPASLPTQTYSTMAPKLHGRAFYESIGSPKHVIAPMVEQSEFAWRMLTRSFLPPDHRTSILAYSPMLHAKLFAEGPKYRVNSFQPLKPPLAISSPGDSEHAKSFTEDDVYLDGNPQIDRPLFVQFCANEPDVFLQAAKLVQPYCDAVDLNLGCPQGIAKRGHYGAFLQEDWDLIYKLINKLHKELDIPVTAKFRIQETKEKTLEYAKMILSAGASIITVHGRQRHQKGHNTGLADWTVLRYLREQLPSDTVMFANGNILQYGDLQKCLNATGADAVMSAEGNLYDPSIFAPPPPVGAEGCEYWRGQDGKGGYRADAVLRRYLDIIHKYVLRQEPPVRKPLFVPSDPVSEEEQQEPTRSDGQKREREEDNEEHQDSSAKKQKLENGRKSKSQKKAERVNQKQNGTKKPKPERSNDPNFTAMQPHCFHILRSLVNDHHDVRDALARSRSGDIEAYENVLVLTERAVKVGLLDYEKDPSKYEYPDPEEQEATDPQLSSTEAVRRCKRPFWVCQAYVRPLPQEALEKGSLSLSKKEKAKLEAQQAEKEKAGVPAEGKIEVVNDPDSKATTANASDITKEQTEIPRDGVVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB88</accession>
    <name>A0A9Q8LB88_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758575.1">
        <property type="nucleotide sequence ID" value="XM_047902662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB88"/>
    <dbReference type="GeneID" id="71983392"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03514"/>
    <dbReference type="OMA" id="GDPWSTF"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF18">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="637" mass="71687" checksum="013C6A388137FF12" modified="2023-09-13" version="1">MPNLPPERPKKLQRISQACDLCHRRSIRCRPSTENPQHQCQNCYDFAVDCTYKRPSRRRRNQSGQNGAPPNLQPAQQQGVSPTSPSIKVEGRSPTFSNGNGSTDHHGLHQVMREGMPQDSLNTAWRYFAMASQSTIERLMDVYMEVVYPLFPFFHGPTLRSRLHNLDYLKDRGFFASIMSACALAAARVRDGAIEGRYHFEENLGGITEMFFSAAQDTIPKDIGTAQGLGYMRACALLAITSIQYGQIPTMHQYIGHYHTLSAIQRFHDESQWPENITLIEKEERRRLFWAMYSWDVYTSIVFNTILKSQESHSNVRYPVESTDEELLSGFESPTNNQNWLRGWNFTTDLYRVLEHTVGRLRRNNQARGDRLDVARLTVSDAIPDTHVMHSVHGLYDELPDRFKEYSMAVTGDMNHDIFGFQAANIQATIQLVRIALCECSPQLDLWRKCDVVDHVINAFRSIQGHYLRAISTPLVHHLGAIGKILSTLMHGELNLDSYDRVRGSLGGLADLLEGLESTLQPTAGASKEIRERIQIIDHFMSGQRRELEAFNSGQANIGDLAGGLGANGTSIYPNGTSGAQPPTLRSTNSLGMHTPLDAFQLPHDVLGEFPFPIDFQEHANNGTQAIPQTNGHVLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBY5</accession>
    <name>A0A9Q8LBY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758935.1">
        <property type="nucleotide sequence ID" value="XM_047902100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBY5"/>
    <dbReference type="GeneID" id="71982830"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02952"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF3">
        <property type="entry name" value="(3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="38"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO14569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="199" mass="22041" checksum="1FE221813F9255B8" modified="2023-09-13" version="1">MSLLQYGVVRFPETGLNDAGHVAFAARFGELDDVTVQQASILRAAQLPPAGTSGATEFADSRSAYDDLPQDLKSLRQQKDYVACHSLYHSRKTASPEALPGLKPEDHFMSRHCLVQKHEASGRMNLYMASHVHHIGGLETEESRVLVERLYGLACKGKYVVSIPWDREGDLVVWDNTCVMYRSTGGGLGLRESLLEVCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCP0</accession>
    <name>A0A9Q8LCP0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759416.1">
        <property type="nucleotide sequence ID" value="XM_047907905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCP0"/>
    <dbReference type="GeneID" id="71988635"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08757"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="13117" checksum="C3CBD336BA11D1A5" modified="2023-09-13" version="1">MSQGPQRWYDLIWLLGAPLSIYIWNMKHKERIERARALEAQNIAGAVPERQEEAPQQDPFHVFEQSKRRWTPAGKDDEHDRRVAEHIAYEARLARSSPKIVKLASGKTLSLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCW6</accession>
    <name>A0A9Q8LCW6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08233</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759493.1">
        <property type="nucleotide sequence ID" value="XM_047907381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCW6"/>
    <dbReference type="GeneID" id="71988111"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08233"/>
    <dbReference type="OrthoDB" id="3649706at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050457">
        <property type="entry name" value="ZnFinger_BTB_dom_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105">
        <property type="entry name" value="AGAP004733-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105:SF28">
        <property type="entry name" value="ZINC FINGER PROTEIN 37-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040249920" description="C2H2-type domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="53473" checksum="1C50D60ED56DDCC7" modified="2023-09-13" version="1">MISYNTRSAAILLLVVALATCARANPDGGAFDSMDWSWDLFDSVGGQFAAGLVAGSSHININPMISSPRDGSSTLAASPRRRSPPRSQPHSNIVQAPAVAPQTDYFPFTNLELSDAWEAQTQSRDVATHPEWSSYSQSAPNDQRHHRISAASNRLFRPQYQQSITRELDQAAGIAAQPPSQPSRDQRPSLDSSNIYGYPGAPQVPVPAEQWTVQESHNVDDRQQARAFVNHEFQSYPRTSSEAGMMTPTPLLETPFCPEAPYLSPQIPQILPFDVTSSPNYHPGMVNGAVGYMQGWARRAPAIGCHARLSINTAHLAPPEDMAANRSPTSASTTGSSTRPGSRRSREEMMGNFVCGYCKAGFPTQGELTHHLRSHAPYMSRLHVCNICEKRFQYKKDLGRHAPKHDPNRKKYYCTFQGCFASFFCFPMTMARFHDRYDSMAQWHAWRQDWYAHYCIVFLSYNLVWFSSIPNFRKGCAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDF4</accession>
    <name>A0A9Q8LDF4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759744.1">
        <property type="nucleotide sequence ID" value="XM_047907721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDF4"/>
    <dbReference type="GeneID" id="71988451"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08573"/>
    <dbReference type="OrthoDB" id="4426945at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="9613" checksum="217139B851A799B6" modified="2023-09-13" version="1">MASLSRNLKELIAERLNVSLEKITDTADLKEELNLDQSDRSKLTAALSKRFDISITNEDTDRFVTTRDIFLYVENKLWWYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDU3</accession>
    <name>A0A9Q8LDU3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759954.1">
        <property type="nucleotide sequence ID" value="XM_047907565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDU3"/>
    <dbReference type="GeneID" id="71988295"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08417"/>
    <dbReference type="OrthoDB" id="9985472at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF43">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="70"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="24468" checksum="1AF8A81F8953A058" modified="2023-09-13" version="1">MWPTSSRLLFTSSHIITLTLQKTYLNSSPRILDTQYCNKRLLTSTPPATMPRDPTGDPKQQSEDKFRDGMSGSCLCGSITVHIKDSQLFSKKRGHLCHCQNCRKVAGSYVASNLLIEQEKVTIDDRDTTLKTYEDYETLSGNPVYRSFCGKDGNPIKSETAAYPGKVILKMGIYPRIPQPEAEGFGLHKHQWQGQHNDVDTYEIKWAGPDKKLLAKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE95</accession>
    <name>A0A9Q8LE95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_05041</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760150.1">
        <property type="nucleotide sequence ID" value="XM_047904189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE95"/>
    <dbReference type="GeneID" id="71984919"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05041"/>
    <dbReference type="OMA" id="HCILIGT"/>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07387">
        <property type="entry name" value="MPP_PolD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.430:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041863">
        <property type="entry name" value="PolD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="12">
        <location>
            <begin position="49"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="11">
        <location>
            <begin position="222"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="506" mass="55845" checksum="27D59FB52948E0BE" modified="2023-09-13" version="1">MATDTAMDEDNPLLEAPSEDHQTLERTQCIYNPLYTYSLPAAQKHYQQQYADMYFARLAQLKPAVERIAAEAFNGVEIAGEICKKVDRVLDVRQGELVWVAGTCYMELPLKPNVLDDIGKEHWISAPPNRDKYATVNGQESFMLEDESGRLKLTGASLQGCLLVTGAIIAVMGTENSDGDFEVLDLRVPDLPRQPARWERDDGAVVKEGKKVQKDRPLSGKVAIVSGLSISGDEGDTLALDLLMEWMLGEAASLTDQEGAANISRLIIAGNSLAHAQPIPSREDVISAKKNAQKKYGYDAASYNAAPTDRLDTFLATLLPSIPITLLPGPTDPTSTSLPQQPIHAAMFPHSRAYMENIAPSAENEPNWFDSVTNPVEFDIDGWRFLGAGGQTLDDVYKYVHGEERLEMMESMLRWRLTAPTAPDTLPCFPFQDGDRFVLKESPHVFFVGNQPKFETSEIEGPHGETVRIVAVPSFRKTGQVIVMDLESLTPELVTIEVYDGDEMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEH0</accession>
    <name>A0A9Q8LEH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol N-acetylglucosaminyltransferase subunit gpi15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIGH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760407.1">
        <property type="nucleotide sequence ID" value="XM_047903400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEH0"/>
    <dbReference type="GeneID" id="71984130"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04252"/>
    <dbReference type="OrthoDB" id="6256716at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044215">
        <property type="entry name" value="PIG-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019328">
        <property type="entry name" value="PIGH-H_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="4">
        <location>
            <begin position="117"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="23116" checksum="16F9FCE4B2DF382B" modified="2023-09-13" version="1">MLITRRPTQTTVSYTVSTRSPSGGLTSRLASYALLLLRVIAALLVATILLAEFRNTSIHIIYLGPEYTLAWAENVVLDTPVGLLAYVLIANSTWIWRAVICTGITWLILRKGYTEESLLVIRGLGVQTSTSSPSYLWTSSTRFIPTSSIQDIFIHEAFQGFETRFYLSIVVEGEEDVVVVFPSILPRREILEQVWRGARACLYEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEK6</accession>
    <name>A0A9Q8LEK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter fsa7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04993</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760421.1">
        <property type="nucleotide sequence ID" value="XM_047904141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEK6"/>
    <dbReference type="GeneID" id="71984871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04993"/>
    <dbReference type="OMA" id="YNWPAGS"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF160">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="510"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="188"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
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            <end position="171"/>
        </location>
    </feature>
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        <location>
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            <end position="662"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="662" mass="73300" checksum="677F27FDDA69AF01" modified="2023-09-13" version="1">MDDHFYSHRWSDLERAHNDPMEGPSNHRKAEPQSRWSTSSSSQNEKDPAIKHKDDDPMEGPSNYRELEDRFHSAAARPKSQHDSINQLHVDNSTMAALQGDRVSFQPGLNTRTTSPKSPSPTRGRHKARKSFAARASQHIFQMRLSKPSTWVPKGNERTPSEEYEPGTLISNDPNDPHNWSEFQKKLTYLTICLFCFLANVNASAFTVATVALIRTFRISPTQATALTALNVLTFGLGNLIWVPVMRILGKKPVYLMAIVVLIVTNVWSCVAGSYGSLLAARMCSGLGAAAADATVPSVVNDLWHGRRKAEKLMWFSGALASGIFLGPLINAWVVERHGWRWTPGWLAGAFGVMFVLAFLFIRETTYRLSTGMWSEEEKPRKKGFVGWMSLTIGREREKNAGEVVVQTLRDIVGMTVYVQVLWASCLIGVIVGWTIIIQITAGQVFTRPAAQGGAYHWRLGLVGVFHIAGWLGAITAGRVGGRFADALATRAQMRQRLPQRPPQCRMQTLAFWAPVCPIGLIIYGVCVAKTTLWVGPAFGYAIHSFGFAAIANIGITYVVDCFGELASEGLVSLFIIRNIIGVVCSFYCNPWIARDGMPAAFGTMAALEWILLACAVPMFFFHDRLLTWTKTYGPAVRLPAPTHPHTDQTEMQTIHPPAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGC5</accession>
    <name>A0A9Q8LGC5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_04718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGC5"/>
    <dbReference type="GeneID" id="71984596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04718"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="72" mass="8012" checksum="76FD5CA20156A937" modified="2023-09-13" version="1">MSAQYRPASYQVPMTMSHHEETMRSGFPGHDPESYQIRPVLTDLLDTLNMVSAYTTILTLATVEGSADSSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGS2</accession>
    <name>A0A9Q8LGS2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13600)-RELATED"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
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            <begin position="16"/>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
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    <sequence length="847" mass="94159" checksum="C185F894E80CD9A3" modified="2023-09-13" version="1">MPSEVPDPAELTSSIPRHDNTSETGKRQRQPSQSSQSPGQQPGDETPSMRGRDTLIRPQGLRGSSRDTADMYRSSTPPERSNSGSIKYTRTGRVSKATKGQRIHHCEECGKTYTRAEHLRRHQQNHKPGAYPCDWPSCGRSFYREDLLVRHKARHNDPLNPPSRRQSIGSRSSSAEFGRLLPGSSQASDSLRATTETSVVAPDLQQETSGSVPHQSSSASRTPKRVPIPPNELRSGVPLTTNGPEGFGSFTNPWEPTPPLSPTGYNYDYESSDEAADVFFYQPQMARARNFSDTSFLGYGQPYSTSRSPVSVGSSTQIQRWSSQPVCETQYFPDAGSLVGSLGYPTPEYTADLACCDPHSATAEVRDLMEHSELNMLDILLGCRQGNEDITPYPMHQQYLAAYWSQVHELFPIIHKPTFDHDAANPLLRAAILALGGQASGHRTDLSNARTIHEKCVKVLKQRMISEAHAYRVCDMQAIVLVEVFSLFKSRRPPLRLSKHFENVYSLLSNDTVAFMSSPSPEMLVAGSFSDELFTETACRQRLLLVCYVLEQQYSTFFGRQPTTCFNNTVLNLPYPTSQNEWDAVAGMPPSGQYERTSQALQDLQFIPEPMGEHVDPFRSMLLMACRFDAPKDLNGWADCCEDFPIALTANLTPRVRLAYHTFVLCSNTPIRDLLAVAGESWILAEKLGTQAEYTAAQIEARQWAARPFSYGEQPPVQEALNHAFAILSVHQDFPKTGLLFQEWATYLAALVIWARVHATKIEEVQPRLSIPTPNVPQVPLEALDSAAAGLILNASTIGMKWNDVLNILLWTRSKIQKQDPHNCGLNSGAVDVLGTIIARGNERGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH63</accession>
    <name>A0A9Q8LH63_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">CLAFUR5_04018</name>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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            <begin position="59"/>
            <end position="97"/>
        </location>
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        <location>
            <begin position="72"/>
            <end position="88"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="16847" checksum="B531838007C60DE7" modified="2023-09-13" version="1">MSLIDRQREVMAHAWHCFDAEPKVNCEKLAALAGFANAASANAFWHKIKAKLVSTPNSAGTISKPSGIASKQRGRLKGSKCISKKPPKLKSSASGKKLEMSTGGALLPMQRIPLESGSLNDRSGHFNHRSSPQDTAAITGVILPDGLEEASLTLNGEEG</sequence>
</entry>
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    <accession>A0A9Q8LHA4</accession>
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        <submittedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
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        <name evidence="4" type="ORF">CLAFUR5_06549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO17422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905697.1"/>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="423" mass="47224" checksum="24806132DFE34D6A" modified="2023-09-13" version="1">MSTGNGANGVRKPAIRAPKVGHKKSRKGCQTCKTRRVKCDEVTPECGNCQRLGLDCVYVTPESTRTRPKSMSGEAPSRPIKLSPGAISEDSPPDSNGDLPSQLVSAPPAPDLISEESEQKRYMELRLLHYWMIQVSRPFGMTSPPEWKELWYGEVPQVALDHKNVLYAMFTMTATHMLGRGARDPAIYTARESYWIMALREQTSAVSDLDNCNTDAVAFSALLITLNSLAMLQERSLEPYSPPMDWLEVGRGAFTVLPPPENVADGTGLKILMETTAPIWQAAYSLEADIKKEFGGVLNREIPSADVWDEETTESYETALSYIAAFRRVILSGEAADINLRWICMFPFMVPRKFIDFVGEMRPRALVILAYFFAVIAHTDALQYLGNSADNATAKREIYAIRRVLPEEWLSYMAWPLQEVAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ8</accession>
    <name>A0A9Q8LHQ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase omega-like 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        <source>
            <strain evidence="3">Race5_Kim</strain>
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        <location>
            <begin position="32"/>
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            <begin position="32"/>
            <end position="49"/>
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        <location>
            <begin position="56"/>
            <end position="67"/>
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    </feature>
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        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="47906" checksum="424ACE7C6C4C8D7E" modified="2023-09-13" version="1">MTNSTSDHYYNKRNDVLIGEIFHSQLADLQNFTSSSSSQRPHATATKSSPAALGQTPPSMSGHTTQPDGEPKPGSGVPTHAHADKDGHFRRKDSAFRDRISRDSNAKFPAEGGRYALYMNYGCPWAHRAVLVRALKGLGDGATGREGVVEMIATDFDLTENGWLFTGKNGSEEKDPLYGFKGLRELYIKVDPEYTGRYTVPCLFDKKTETIVNNESSEIIRMLYTEFDDLLPAELREENKEGGGFYPEHLRKEIDEMNEWVYNTINNGVYKCGFATTQEAYNTNIHPLFASLDRIESHLSSPSHQPFLFGPYITEADIRLYTTLIRFDSAYYTIFQCNLRSIRHDYPNIHLWLRRLYWDETERTKGVFRETSFLEAYRYGYARARGRMLRGGKDLEDGREIVVPGGPEVGVEELKDGQRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <location>
            <begin position="95"/>
            <end position="155"/>
        </location>
    </feature>
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        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
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        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20434" checksum="51FBBF719AC1B930" modified="2023-09-13" version="1">MFYTMYLSSLCQRRQWPDPSYEPFRTRNGHFCKVRVNNREYSTEVPYASEALARDGAAQKAYMICRNFSVNDGMFPGQRPGQMTSAGAIQGLPVAIGTGRGSKRSSAASCDTASTDGTSSGDNSPRSLESGFEQQLRQVTQQVPKPPARSNRSKGGADDYVCYCRRAPVRAYGRCAWCLRESGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI00</accession>
    <name>A0A9Q8LI00_PASFU</name>
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        <recommendedName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="5"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="33817" checksum="F0DFE56E38CCCB84" modified="2023-09-13" version="1">MPADEAVLWDGESLRRGQCLRNGKFTFTLQDDGNMCLNYNGEYLWGTSTQDKDVQTATMQSNGNLCLRRSDNDFVWGSMQSGGNMVEPGSSPYLQLHDNGNIGIYKQHNGAGWVVWSSNTQLITFRAVHFRNMSRTVYTYPLIKDRDGSSTLWDGKASNIWAMVPQSTPGWSQIAIDWKNAYYNTDRKHYLRDEVKGVVKFGHNIRWGDDVWVNDWQFIYDENSTTSVHITSDASARSGNANYDGCSTNLWFDPRENHDLSLWTVDDSMEVHIFYRNSEWDGTIRKPDFNDIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ71</accession>
    <name>A0A9Q8LJ71_PASFU</name>
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        <submittedName>
            <fullName evidence="5">Deoxyribonuclease Tat-D</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05948</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO18370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762736.1">
        <property type="nucleotide sequence ID" value="XM_047905096.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71985826"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05948"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="14856" checksum="894C7E415491D611" modified="2023-09-13" version="1">MWGVEGEAMVRFDKGHISCMASSFTQDVARIRDLSAESPGFVSAFGELGLDYDRLTHASKEMQIRTFKAQLNIFVTEKLDLPLFLHFRAACEDFIDIIRPYLPNLPNLPRGGLVHSFVGSKEEMQALVDMGF</sequence>
</entry>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="11918" checksum="79FA42AA883D3481" modified="2023-09-13" version="1">MPFTIAKATPDDAAAIAKVLLSGGTETLMYSSRSFTGFATRLQLGTIDPAILEVDMTEKIAVNIKKPNQTWIIARDEEMGEIVSYAQWELPAAHDEVVSEPDPNVSDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="EMBL" id="UJO10997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="119" mass="13180" checksum="DA81BA8ED829D637" modified="2023-09-13" version="1">MITSSDHDEPAQPEIETINNGRATILQNRGLRDALKQNRSSKDQRGCIQKTEVQPYRISKPSTSHRREAKSTMQERQSKGLKPKACIKSYRTATVPAAGRASVPEIVDLCSTDSESVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P361</accession>
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        </location>
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        <location>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="52396" checksum="0E935A7B0E6B0F05" modified="2023-09-13" version="1">MAIHRGIQSAIFYYLSCAPCSEARYRRKRKEEAKRGRAERELLEQAHPNFYRHPSPSSTNPYWQAEIDLGPQGLQRGKRKTQAADSRRRLRPQNYGSGSPSWDKIPPATASNDGSDSRWNFRRYQREDEELWGSTSNFGGSMYGDGLTRPQRARTKDSSRSDFSGYRNPQINDMHPATFTRVTTREEVMWMKQPPPVAAVISGKERASRSRSDSEGSRLSPAGMPLSRSVSHRIIEQKLKAVEAATAMSRESSSRASDSQQHDRRPGTAERDFAIAPIQSEPRERRRPSPIQILNDSEDSDDTVVRRPSLAPEPLNRLQARRIASRPALSTIASDEAVPSTIRSGLHTPEMAKENDVPTPVHSSDGSTDAYDQFTRRSALLVPGNALREKIFRNATDPGLGHGDTTIRRHGHRHEDSEDTVLALAPELVDLDSWVESEFDIIKWAHEFTKREVHPKERRASMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3H6</accession>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756127.1">
        <property type="nucleotide sequence ID" value="XM_047901037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3H6"/>
    <dbReference type="GeneID" id="71981767"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01889"/>
    <dbReference type="OMA" id="SEESHMF"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF9">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="6">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="499"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="564" mass="62643" checksum="BBBD8349CA0D9EB6" modified="2023-09-13" version="1">MPDTARYVGERLSLKRQLCTIRYIGAVADKLGEWLGVEWDDSDRGKHDGTHNGVRYFTCRSPTSKPGSFLRPDQQWDQSKTFLQALREKYMPEDAGTGGDIVYFSTKQAEEVGFEKFSKRQARLQGIHVLVLDHISIRFQNEDRETITELCSDITELDLSSNLFESLGEIVELAVLFPKLTHLTLNGNRFPIPDDCSKAALKQLTGLRSLGLSDTLLSWTEIAKVACIAPNLTTLSAARNRLNRVTSDPLPSTLAHIVLSDNDFDALSDLSGLSSCTGLSSLTLKRCHISTNGNNASDIIVYSRSLQVLDIAYNRVANWALFDILEETFPALESLVITGNPLYGSLSSVEGTTLTAEDGYMLTIARLPRISFLNYSKVTEKERLNSETYYLNQIVSELGKTPADKRPQVLRTHPRWKALCEEYGEPAPKETKSDTINPSSLAARLVTIDFNVSATYDSAAVTRKDTVPKSMNVYALLGMAGKRLGIMPRKLRLIMETGERDPTGSEAGHAGPEWWDSSDDEDEQPRVGQKLVAREVELVAGTRPIGTYIEGREAQIRVEVKGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P455</accession>
    <name>A0A9Q8P455_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-coenzyme A thioesterase 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00383</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757086.1">
        <property type="nucleotide sequence ID" value="XM_047899531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P455"/>
    <dbReference type="GeneID" id="71980261"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00383"/>
    <dbReference type="OMA" id="MKFERLP"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="28"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="180"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="304" mass="33506" checksum="871B1F137F10E1C7" modified="2023-09-13" version="1">MAIGTMEEGIRLKRVSENTFQSIATPFTWADGVVVPGGLLMALSANAAFETVSQDFSVDSLQANFLLGPRTDLPMDLEVTQLSDGGRFAVRMVHMKQGGRLLVHSTCTFVRGLRGESMQHTTGRATTETVDEITLDDLEVDRNDRGPYMKYQRLGVVQTGGKDATEAPPDAMTYTSVCTVSPRISSNTARLHSIGIILLSDYHVLDCPPTVHGLSTGQPAIGDHQRNIKASHFKYLTSLNHSIHFHVHEGFRADDLIYLEANSPWSGNRRGEILTRMFTKDGRLVATCKQEGYYVLHEKGLGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4B8</accession>
    <name>A0A9Q8P4B8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757055.1">
        <property type="nucleotide sequence ID" value="XM_047899417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4B8"/>
    <dbReference type="GeneID" id="71980147"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00269"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="234" mass="26793" checksum="B63F47C325B9C78C" modified="2023-09-13" version="1">MAQSSTNGARYLLLPYNKLGDQIRFLFVGPHQLSIQLHLDLLPKQTQQWLTTKEIRYDPTGLNFPCYPLPDQDPGTVNLYRLWLYTGKLFSITPDDVDVEDDGEVEAHEDAEWHKLVLMYLLGVEARDEKFANIVVNALVEKTYGDKLRKLYVDLHVWVGQGIGIRNPHEDAAGPWEFLDDVRSSKFVAGRKIYDPEQNAPYEDRLCELYHKHDLTAMCGLEGMEVLDLTAEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4H7</accession>
    <name>A0A9Q8P4H7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00411</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 17">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757354.1">
        <property type="nucleotide sequence ID" value="XM_047899559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4H7"/>
    <dbReference type="GeneID" id="71980289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00411"/>
    <dbReference type="OMA" id="DYPDATT"/>
    <dbReference type="OrthoDB" id="1470711at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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</entry>
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            </authorList>
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    </evidence>
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        <source>
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    <sequence length="399" mass="44441" checksum="9E9BDD588E0397C2" modified="2023-09-13" version="1">MSSPTSPSRKRAHSDISNPDPSDKQTSNKKARNEDSPPREKTESPIKSAGSVHRVDSAEVLESSAQAPPPKNAAAAPAPKGLAVVVKKAAVKKTTATRNGTDDKLKRLEAELEKARPENTKLKEKVEGYEQKSNTPQPWTQIDEDRLMAAKQGRTVPPQIHPAQSQQKIQELEKKITAQDDMIKNQAAKIREMVVAQKDFTERFNVANGAELRVILKAKDAQMASDAAALAEIEKRVKQQDEQLETLLLDKSLQDQRIKTRDADINDGVRLRKLMSRQLDEKNDEAKKANEERAKTMAVNVDLEKSVKAVFEAKAGYKKTIANLEEHNKDMKKALQKKDGQLKSIGERCAKRVSFIAQTKQVLRCNNIDLPKPLPGMEFSDWKDDKGPEEAVKVFMGGK</sequence>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            </authorList>
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        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
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        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="75" mass="9101" checksum="CE237376F973505B" modified="2023-09-13" version="1">MPPRKAGIGSKTTLLTWTGIFLFFVWGQWKHSNPERREKSRKYSRKQRERDDRRKDHKKGYTVTRDRDRTAPIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5S7</accession>
    <name>A0A9Q8P5S7_PASFU</name>
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    <organism evidence="2 3">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5S7"/>
    <dbReference type="GeneID" id="71982898"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
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        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="58" mass="6665" checksum="4B51B3A7B5BDAA54" modified="2023-09-13" version="1">MQHFTHFTFNFLDKLAPSHSSTRYGKPNMARIKALADQSTSSKSAKAKKRFRLLKLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Z6</accession>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
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    </dbReference>
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        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
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        <property type="entry name" value="AMP-binding_CS"/>
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        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
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        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
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        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF12">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE IVOA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
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    </dbReference>
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        <property type="entry name" value="CoA-dependent acyltransferases"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
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        <location>
            <begin position="26"/>
            <end position="802"/>
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    </feature>
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        <location>
            <begin position="254"/>
            <end position="616"/>
        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="802" mass="88304" checksum="2280D26AFC33AA16" modified="2023-09-13" version="1">MSVLARAAWSLLVAHFLASHDIVYGVVINSAVPSAGGEAVTSPTQVAGPTNAVIPSRTRLDFDTMDVSTLLARLHQQSVEEHAHAHLGLTEIASLSTACKAACQFTTILVVYQTRTMNGNANEEEHFDLQNHHIFTRDRRLVSEPINLEGQEGFTPHALVISCHPFEQSNKDFLGIHVLFDSRLITKLTAETVLNGFSTLLHNILACSPETPLRSLSALSGAPNYGPSSLPGGIGEAPEPVSAFAHELISSSAMLRPQDEAIHSWDGSMTYYELECSSSAMATKLAAAQQTSADEWGVAFMLDRSKHALITILAILKAGCFFVPLDPQHPIIRLQNILRTVNVSMIVSQEKYQSILQELPCNHLLVEDVDFRRPAHENNTFASQTEEMQRIQDCVRVRRKDCDPAFCTSYVIFTSGSTGQPKGVVIKHEALSTALVALGRSPPLPERSRFLHIGNYVFDVAIYEILVTLLYGGTVCIPSEHERHFDLEGFIGSARVTDAATTPSVSRALDCEKICKSTGLQRLRLGGKAVGLQGRIRWNRPESDLPLHCIYGITEAAIANFHHPVRGNDVIYPRLIGKPINCKAWVRSVHNPSELALPEAVGELCLEGPVLAAGYLCDPVRTAEVFVTEPVWLPKDRAHELNKYSASKRRIYCTRDLVYADHQRQTVSFVRRKDDSRQFKLRGLRIDLQEIENAIENVSAAGVAVELLTPPGEQPFLCACVHCTELGNSKTPRTPFNLRDMRDALAQTLPSFMMPSYFVSLSSIPLSAVGKRDHTALRAMMESAIVSERASSRSLDTVLLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6F4</accession>
    <name>A0A9Q8P6F4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO15090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988656"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08778"/>
    <dbReference type="OMA" id="RYEYDPI"/>
    <dbReference type="OrthoDB" id="3946750at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1281"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="290"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="901"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1168"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1265"/>
        </location>
    </feature>
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        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
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        <location>
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            <end position="122"/>
        </location>
    </feature>
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            <end position="195"/>
        </location>
    </feature>
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            <end position="215"/>
        </location>
    </feature>
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            <end position="242"/>
        </location>
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        </location>
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    </feature>
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            <begin position="305"/>
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        </location>
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        </location>
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            <begin position="1248"/>
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    </feature>
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        <source>
            <dbReference type="SAM" id="Coils"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1323" mass="150269" checksum="D6BD6BBA38701317" modified="2023-09-13" version="1">MLPPQLQYSLRKRSLSTGSLDIVRASTNSILRGGVACSQTRSFWGWRRCDYTSHIDPMFHRFVRYRTLKTRAKLLDKLRRKGRWNWDVEQRPFFSPKHVRLAHHIGRPRWRYSQDGDKKGGEENAEEDSYELSQREKEWKDQMESMRKRLETDPYEAVFGRRFEPFWSPLVPSWMREEMGLSRWPKPKETPRESESTAQSNVKPIPKAPRTPSPEPVDNAKPQKKTVDSDGETPNGQLTTFPYNPENILTEPEPETPNGQLTNYSYSSSTSWDSWNKKARKEEWDSVSNETRRYEYDPISNRMVALDHPKSGEPHKMDTPTASSEPGAATDLRALASTLRENMDAVKSTAADIPSNTSKEARTAIPVPTQTTPPPAHKTSVYFPSLINTSVVPKTKKSSSVAMVPKNELNSLTAAEVRASVGKAKRDTITEQRQHDRAYRHGKLDIKRSPWDQAETRIMLEKELDGLHDKKEALLKHEGGLYHIEKQKKELAKIEQKSVEVSKQLRNLDATEAKLATGEPTGAFVFDKANKSTGLETALSQKQNLTSTSPPQKSSALQQSLQPSLERMQSKELSLADELDDSAAHESTGEPINYKTTNVPRDWEKQADLLQANRVQRTRGTSLPEIDLAADINAKNAAKSAVEDAIEAKKTGARWTDIMNAKRAAWEAEQAEKKAAIETRDASKNATLEKANAMLESEVKEQKFLVQAHENRYAHKIRSLRQELDTAYKQSSVQGDMHTERIRSLEQDLERAQKAAGETSKVEKFQTERERYQGKTRDLRSELDVAFKQSTIASEKHVERIRYLEAELEKALNHRTDTLEVEKQRYVGKVKSFREELDRMFKQSSAQGDKYVERIRELEKEPEEAWRPAAAAAARSVEATQAEGDFSANVAKYANNAKWYKQPQHNTATKSTGHEAEKAAQKQENQELVREVKKPYESKYGTIDVNHGQPIGQPASRTTKQAQQVVEVESDVDLGKALADYEYEQRYGYRKDNLEAEIAAQEKAAHEAQALIAAESSGKMRHSIANKLGHDLDSQSARIVDDTAPRLIPTEIIARSKQETASSKEELNTFGITWEEPPVYKVLAYDSGNDMFSTATTSSNFTGNEHPISIPEALSQLYQPARFVPHFSELQREGYQVIHGTKDLLVFKKVKNSPPALSLVDHGLVKPATEETSTTKTPNTTINPVDGMTRTIEPETGSFASPTGFVGDRWDNTTSADNLTDSLKDYDQKHSYNPRIKREERVFSGSRLSRKERRRHHHEPSTEQVKEYKKKWKSYRSRMRWALGVGLGASCVAYGLGAAAERKERRERERWEEILEGRKGRWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Q1</accession>
    <name>A0A9Q8P6Q1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759634.1">
        <property type="nucleotide sequence ID" value="XM_047907742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Q1"/>
    <dbReference type="GeneID" id="71988472"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08594"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="12978" checksum="AD84DE5080DEFF5C" modified="2023-09-13" version="1">MDSTMSGNMSMTVSRKRKAPDDDLRLEAALSSGLRVLRLEDDQDQVKEGGLLTLEGEDFPEAAKPILKPVKLPSDGPISLRQYAEILAKTEALGEVKEEDEEVHEDDQVRMEGVVMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_08281</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P742"/>
    <dbReference type="GeneID" id="71988159"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08281"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="484" mass="54578" checksum="9B777F64B1F1B5AE" modified="2023-09-13" version="1">MHINDLPEEILSDILLLATRANEAEGVSFTYGLTEAQLPLQKQKIQKYVRGPVTAEHMRWDATDSIRGVCHRWHEWAISYNLEDVFERKWQGGERWANLPVSRKPNALYDMIQYPSSTPLRRDPYGSLKNTNRIFKALPYMTNHVRRLWFNGFYTKESDSLILSAVSECDALQTLTVPWTVLRRSSAEDWIDLLNVNTGHGSPLQSLELQAQCLRSEEADALEKDDSPNALADPRVDFSALKRLRIFGNTLHKPVCDEDLQLIARTATGLEALDITNLSTVSVAGMLALVKASRETLQVLEHSPRSDDGFYHPYPGNLATNEHICELLTSLPRMRDLSISVPYMCADLFSNVEVQWEGECQVRATDLCGCDSSTPSKARAHKLRQVFSAARSLIASRARMHHNLSIELFFAGCIFEPAKNLVHGDFAMTQVHSHGQWPRQTELSTKGPYGTTGVYGDGKGDDSTWDAVWEEEYLRAVEAGWVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8I3</accession>
    <name>A0A9Q8P8I3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761539.1">
        <property type="nucleotide sequence ID" value="XM_047905059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8I3"/>
    <dbReference type="GeneID" id="71985789"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05911"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="23628" checksum="20EF55510F4A7298" modified="2023-09-13" version="1">MADSSQQLLDVSRKNEEAVSPAAASTNASSPLPSGYKPPTVEEEQPSNEATVAPSTAAAPEAQAAGDLPIAGAIEDKADRVAKIMAIEDNDEIFKATEAMMPNHDVFMAWDAQFAGMKYRKTAKRAKYADMYKALQESKLEHIDEDKNAYRDLRWQAQQRARAQGIESNARYSRAKLCTPEEHRLLDIYGQRDVYVQERRFAGAGRCGGTNTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P928</accession>
    <name>A0A9Q8P928_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762216.1">
        <property type="nucleotide sequence ID" value="XM_047905253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P928"/>
    <dbReference type="GeneID" id="71985983"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06105"/>
    <dbReference type="OMA" id="QYEFQMW"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="11"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="230" mass="25110" checksum="96BFA87A03A709AA" modified="2023-09-13" version="1">MADEMSLSQLPLTLIVAATAKNGIGKSGGLPWPMLKKDMAYFARVTKRVPIPQNTGSVRSDALKESVLEGASRNVVIMGRKTWESIPPNRRPLPDRTNIVISSQDKSTLQSVPEDVVVASDISSGLQTLEGMVKQGKALPATRAFVIGGSSIYTAALELPQTKRILMTRISEEYDCDTFFPDVLDSFSSGWEKASHADLRSFVGEEVEEGPVAQAIDGEDVSMEFELYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9G9</accession>
    <name>A0A9Q8P9G9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762413.1">
        <property type="nucleotide sequence ID" value="XM_047905302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9G9"/>
    <dbReference type="GeneID" id="71986032"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06154"/>
    <dbReference type="OMA" id="ETWAANG"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040490297" evidence="3">
        <location>
            <begin position="17"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="34"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="132"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="548" mass="60280" checksum="BA266115B797BF6F" modified="2023-09-13" version="1">MRSFFAIASFAGLVSAAPNAQPAVKRQSSYGASPPTVTIKNGTIQGSHYAAANEDYFLGIPFAQPPTGANRYRLPQSINTTFDGAFQATQYAPECYGYGGDQIGYPQSEDCLYLNVVNLTFIVENSVQIGKPIIAISIAYRLGPWGFLNSREVSESGNTNLGLRDQRLALHWIQENIGGFGDDAEKVTIWGESAGAASVGWHITAYNGRDDKLFRAGIMESGNPIPYNSYFSDERHQPKYNDLLEATNCTDELDTLDCLRLVPEATLQNIFNTTSLNSGWSPIVDGDFIQRWGSIQLAQGAFVKVPIIDGANTDEGVSFGPSPVASEQVFKELIINNSGNPLTAHWADQVLEAYPLSPEYFIPPVEEVPANYTWPSSYGNSQQYRRSAAYSGDFSFIANRRATAEIWAANGLAAYSYRFNTQPAGAKPIDGVGHFQKVAFVFDNTQGLGYDAEHGTTNPFANRTKPYYELAELMSKSWASFIYDLDPNGWNGRDGLGSGPDAWPKYSLEQPENIVFDANETGLAVTEPDTFRAEGIRWIIDHQLAYHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9I3</accession>
    <name>A0A9Q8P9I3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762559.1">
        <property type="nucleotide sequence ID" value="XM_047904752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9I3"/>
    <dbReference type="GeneID" id="71985482"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05604"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040134269" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="14681" checksum="60AA6B813E6AC59C" modified="2023-09-13" version="1">MLTTLSILPALALFTTSISAAPIQRAEASVNTALYNYPLQAPSAGQPFTSLQLRIGQPYIDGTGCEAVVIREALLGELLSIVDVYRCVEDGSLKGAFISFSSFPDEAKRLRATETFAEAYPMIEWFLDDDISAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9I5</accession>
    <name>A0A9Q8P9I5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cercosporin MFS transporter CTB4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cercosporin toxin biosynthesis cluster protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06249</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin. The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules. These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids. Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762458.1">
        <property type="nucleotide sequence ID" value="XM_047905397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9I5"/>
    <dbReference type="GeneID" id="71986127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06249"/>
    <dbReference type="OrthoDB" id="3357846at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015244">
        <property type="term" value="F:fluconazole transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="92"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="516" mass="57175" checksum="A0E5A7E171A3DC7D" modified="2023-09-13" version="1">MPLKDFFRETFVGRMINIISRNRLLRAPTPELPQSDKLGHQLSRQSSLNRSASRSSADEIAEKGAGGHLVDWSSTTDPDNPQNWPLWKKLYSTAVICILTFSIYVGSAIYTVGLEGITEQFQVGHGTATLGLSLFVFGYGIGPMILAPFAEAPPIGRMPVYVITHLIFLFLNFGVVYAKDIGMLLAFRFLTGFFGSPVLATGGASLGDVWSPKKVSYAIGIWGNFAICGPVLGPLAAGFAVQAKGWKWSIWELIWLNAFTAVLLVFTLVETSSDNILFRRATKIRKMTGDKEFKTAAEIEAERMPVKEIVISSLYRPFMLCFTEPILMAQNLYLGLIYALLYCWFEAFPLVFNGIYHFNLGELGLSYIGLLVGAVIFTIPYFYWIRKKIEPNTNEDGTIAPEKRLPAAIVGSLFLPICLFWVGWSARSSVHWIMPISGSAFFTIGAGTLFNALLSYQSDAYPKVVGSVLAGNDFARAMFGCSLLGFLSIAFIPIPIAIYYYGERSRKSSKYARHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9U5</accession>
    <name>A0A9Q8P9U5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762727.1">
        <property type="nucleotide sequence ID" value="XM_047905698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9U5"/>
    <dbReference type="GeneID" id="71986428"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06550"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="27246" checksum="7F92977D33AC4EB7" modified="2023-09-13" version="1">MTFRTHQRQSEAAKSGPQPAPDSKCPTNLFWRDFRGKRHDVEIKGCPTVELLHKQIAENMDAGSYGLMLAWRGHVLYDEDLLAEVLFQASNTDQDLEFDNMDRDCVMNSTDNGISIVLSTDHKLWVSVRSLLESETADIDLSGDSRIDSLVFAVQRAVGYTVVRAYPWTSLLEVAQAFDERLGDAIAQSVYFHQQKPAFDGVEYCRSQGHVVKTLKLANVGPGSVMRLLKVNHDQSGHWVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA63</accession>
    <name>A0A9Q8PA63_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763089.1">
        <property type="nucleotide sequence ID" value="XM_047906249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA63"/>
    <dbReference type="GeneID" id="71986979"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07101"/>
    <dbReference type="OMA" id="YMEYVNG"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF54">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="318" mass="36335" checksum="CC35A5A8066871E4" modified="2023-09-13" version="1">MAGITFDHADLPIGDVYLPGHFPHGLPSPAEVRVKAAQDGIDTRNTFRPDPVLYPELGLIIKWGRDITIAEGQCLWFMSKHLRGVVPVPELYGWTVDSDQTFLYMQLVNADTLQGRWNDMSEDDKLDICAQLRDMMAAWRRIQCPGPTSNDSRPRTILSTVMSWLRFWRPAPAIRLGQICGQALRDILFYNAGQYPAGPFDNVHSFHDWLAKLACANDARKDVEELSGLEDSVAVTFTHGDLDHSNILISKKPDGPPKIVAIIDWHQSGWYPEPWEWLKAQMVAGHSSQWTKEYLPRTLRPARYEYHYSWEYIKMATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB37</accession>
    <name>A0A9Q8PB37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07746</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763537.1">
        <property type="nucleotide sequence ID" value="XM_047906894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB37"/>
    <dbReference type="GeneID" id="71987624"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07746"/>
    <dbReference type="OMA" id="YWAYSAG"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="19"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="503"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="553" mass="60241" checksum="BD781C531799356B" modified="2023-09-13" version="1">MAISVAPSQYWEGNDGPWSTFALQIGSPPQTVRVLPSTSQSSIWVVLPEGCAAEGDPTDCADRRGLLFATNGSTSFDRVGDEYFELPYYEPERDLGYTGNSLVGRDIAILGWDGSTAPLLQDQIITGFAAKQPFLGVLGLTPRPVNITSFVDQRPSPLGTLLADEKVKSSYWAYSAGARYRQPETHASLTFGGYDALRGNVKHVLTAPTGIETGRDLQLAIRSIAIDDDAGRHSAAGLPMYTIIDSTIPEIWLPIDACAAFEHAFGLTWNETVSMYLVNDTHHDTLTAQNASITFTVSDSTDASTSSLNITFPYAAFDMEASFPLAGITDNSSLRYFPLKQAQNESQYVLGRTFLQEAYLAVDYDKSQFHLSKATFPSDAATTDIIVAGSEEESGLSTGAIVGVVIGAVAAVAFMIAFGWWFRRRRRAAKRWSQPTEDKVDGYEHLQQDDEHLSQLPSPELEAGSVVHTKAHPSSQELDGQIANRLKADRSDLKTQELDGEMMVHEAPSGKQDTAEVQGSPMVHEAPVRERPAELWTPPLTEAKNTSDLAELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB50</accession>
    <name>A0A9Q8PB50_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763579.1">
        <property type="nucleotide sequence ID" value="XM_047906349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB50"/>
    <dbReference type="GeneID" id="71987079"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07201"/>
    <dbReference type="OMA" id="YKTADAH"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="102" mass="11565" checksum="EE61CA0C17A29AE9" modified="2023-09-13" version="1">MIIPIRCFTCGKPIAHLFETYVNLISTEVPDPEASAITGEPETKMMDDGDAMDIIGLTRYCCRRMMLTHVDLVQKFLGYKTADAHKIMEDIKKEMSTQGTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBC8</accession>
    <name>A0A9Q8PBC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763720.1">
        <property type="nucleotide sequence ID" value="XM_047906125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBC8"/>
    <dbReference type="GeneID" id="71986855"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06977"/>
    <dbReference type="OrthoDB" id="3650286at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="28199" checksum="22E94E78031629F1" modified="2023-09-13" version="1">MVPIAASKVFAIPELLENIIFQVGNNRRIQKLFSQFSQDYKKRFFLQPNTIEGSLKLKRLMYLAPVDPQLQVDNQWQHCPVEWFVDWMLNPKFDAEITVETGANGSRRAVYWMGDILTCDIRGRCQNLSRISNKLSYFSTAGAARPESSWRRMRVSRSGNDHPIEVKFDVIIGNSNTPFPQCVKWHFEADASLGALFDRFVQLLEALWTEANFFEELDRKRRREDMERVSESKRRLRGFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBD5</accession>
    <name>A0A9Q8PBD5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid scramblase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763722.1">
        <property type="nucleotide sequence ID" value="XM_047906297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBD5"/>
    <dbReference type="GeneID" id="71987027"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07149"/>
    <dbReference type="OMA" id="MIGFEQA"/>
    <dbReference type="OrthoDB" id="191150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="503"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="588" mass="62111" checksum="A5528E0775C32B23" modified="2023-09-13" version="1">MATARWSLRLPRGVSNLHHTGAVPGRVNSRLRPELAPLSQRRWLQKPPPQDRPWASRPGEPKKDDSQNENQDKAIQEGESQPEQAQQPGRNAQLATALAEADTSDLVTEVHIPDGPNAILPPDHPALSILGNSSLVIQRQIEMMNIIIGMEQANRYVIMDGQGQTLGYIAEKDHGLGSAFARQMFKTHRSFTTHIFDRQEREVLRIHRPFAYINSRIRIYDPVPEGGYADMETSTALQGTSANSVVNQGAVSQVSPLNLEEMRIIGEAQQRWAPLRRKYDLFSYRPIEAPRDENLRIESGEKPTSDTIALTESKAPDQAIEAGMVQFAHVNEPFLSWDFTLKGEDQNTIGSVNRNFVGFAREIFTDTGVYALRMDSAAQTSALQDASGQEVARHEREAAAMTLDQRAVMLATAVSIDFDYFSRHSSVGGGGFMPIFWPMGGGAAEGGAAGAGAGAAGGAAEGAGAMEGAAGTAGRGLGGAAGAGSEGAIAGAGTMAGYEAMQRGASGQRGGDDASPTNNEPFGAGQSPEHSENRPGADDVWGENDDPWGGGGGGPPSDGPPPGMGGEGGDGGGGGGGWADVISDFFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBZ6</accession>
    <name>A0A9Q8PBZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764053.1">
        <property type="nucleotide sequence ID" value="XM_047909464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBZ6"/>
    <dbReference type="GeneID" id="71990194"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10316"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="221" mass="25151" checksum="4063A88FBE0EA2A9" modified="2023-09-13" version="1">MNAAHFVLESWISQINILRCREPGSFIHVTYLLDDAEAFMEPTETIIGDGRSIKAWPEASHDAARRIHAKVKSRQESILRIIDQYSYDAADMLIKSIGPQHEHYCGHRPGHEPGERNEDGDEFEMDYDGSTPKKCSFAQDYMLKHLKLLAGAHIWPRGAREGTVNQLLKAVADFDIDYATRHEDVGWRTCNSLACEEWKLKEYGLQSKGRTRACSIPSAYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC73</accession>
    <name>A0A9Q8PC73_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL13m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764158.1">
        <property type="nucleotide sequence ID" value="XM_047909012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC73"/>
    <dbReference type="GeneID" id="71989742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09864"/>
    <dbReference type="OMA" id="HKPIYTP"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000007">
        <property type="entry name" value="50S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00068950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="184" mass="20624" checksum="D41098E6DC93E4D9" modified="2023-09-13" version="1">MSHYLGQTRLSYTRTWHHLSLSTDPRPLGRVASAIAITLMGKHKPTYDPSTDCGDYVVCTSCSELHTTGKKRFQKKYYSHTTRPGSLKEMTMDKMMDKWGGGEVLRRAVRGMLPKNRLRDDRMARLKCFEGEAHPYKRNVLAVSEANGLGGSIGEMPAVKRGLARGQKPKEKKMVKQEAVVQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDN1</accession>
    <name>A0A9Q8PDN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765020.1">
        <property type="nucleotide sequence ID" value="XM_047910006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDN1"/>
    <dbReference type="GeneID" id="71990736"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10858"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
        <property type="entry name" value="ZYGOTE-SPECIFIC CLASS V COPY B GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040408047" evidence="1">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="7923" checksum="7DB78C8AB6DF93F4" modified="2023-09-13" version="1">MFLPILPILIALVALLPTAIGGPAAYGICQAGCASVVVACYAAAGFVFGVALPAAPPAILACNSAFGTCQAACAVVVFAPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDN9</accession>
    <name>A0A9Q8PDN9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11372</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764901.1">
        <property type="nucleotide sequence ID" value="XM_047910520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDN9"/>
    <dbReference type="GeneID" id="71991250"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11372"/>
    <dbReference type="OMA" id="QSTMPID"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="198"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR033096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="46688" checksum="42B5B16F58449DAA" modified="2023-09-13" version="1">MSDLDKAIAQLRACRPIPEAQVRELCYKARELLIEEGNVVSVDAPVTICGDIHGQFHDLMELFRVGGDVPDTNYLFMGDFVDRGFYSLESFLLLLCLKVRYPDRITLIRGNHESRQITTVYGFYDECLRKYGSANVWRYCCEVFDYLALGALVMGAATDLQPTEAAFADPTQQHNEADEIEIEILNSQGQIINRFPRARSSTQDVSQLSNPPSSPSQSQDQTPSRNGPPGTGASGASRGGGSGNGGGAVLCVHGGLSPLIDSIDKIRLLDRKQEVPHEGAMCDLLWSDPDEIDGWGLSPRGAGFLFGADIVKCFNHKNDLSLICRAHQLVMEGFKEMFDSTIVTVWSAPNYCYRCGNVAAILELGEDGSNAGYAPRANGDANRSNGVLSERVENKMGPGRRYRVFDAAPQDSRGMPAKKPVADYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE34</accession>
    <name>A0A9Q8PE34_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron transport multicopper oxidase FET3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765245.1">
        <property type="nucleotide sequence ID" value="XM_047910151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE34"/>
    <dbReference type="GeneID" id="71990881"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11003"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="73"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="317"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="390" mass="43062" checksum="0B58DE5FA95C135D" modified="2023-09-13" version="1">MAYNRMDGAAGITQAPIEPGHDFTYDFTIGADEQGTFWWHAHDGAQRADGLYGGFVVHEPSRQDVGQVLDAEHLLLLGDWYHRSAEDALHYSMHPGAFGLESVPDSVLVNGFGSYACADAVPARPVDCIDSKHIASSLNLDVSKRNVLRIVNVGVYAGVSMSLVGSLLTPLRVDAGRPISAAASKSVGVLHPGERMDLLVQHQQDEADQLRSLIVALDDTRLKPNSRHESAVYETFDIQNVEPAHNQASSLPAQADHTIVLYTLTQKLAHLDNEPRGFINHSTWARPSLPLVDLPRSQWEKTLFVSQIKYNSASPLCVDIVLNNLDEDWHPFHLHGHDFWVLSTYSSNLNWGSYNPYEDATPPGGQYVLASAVKKDTFDVPRRGYAVHGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEL4</accession>
    <name>A0A9Q8PEL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765409.1">
        <property type="nucleotide sequence ID" value="XM_047910477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEL4"/>
    <dbReference type="GeneID" id="71991207"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11329"/>
    <dbReference type="OMA" id="ADKHIRR"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="596" mass="66240" checksum="0A01F1BCF5F9F514" modified="2023-09-13" version="1">MSNNNFTFFDQFDFTKGFAAPDLMAGFAQDDQNQYIDPALLQLDAQSGDGAGQVSASVGVNPQPALDDVDWDNLLRDFPSHDDEGTQAIAVLPEKPPSESVQHHTIPPGSSHSPHFGLQVDRSQFDHDLTSQSFQRTAASARSQVQNLSPNMHHIPNLGRAPEGHYSPPSWSNQVPASLRTPQMQQTFMTGHNMTQNNPYSSPVHSIEAEHQQYASHQQRFTQRPIHGQYSQVQQGYVVRDVEQDSPGIIHQYSPGPEASPDPEYSDAGSRRPKGKGRARDGSTPHENPRCLDCGKRYRLTKSEGRCSRCADKHIRRLAGQQPHTYVLDPSVPDIATARQIVSPLIPGRNLCNDDYHRFAGQENLWVERLLQAVNVVQSEANDGSVWALRQQTYLNEKAELEKGYTDQQVTARLRALYQEIVNYHAGGPAVYAIGGDNAGYTDNRILTFSKRINMICGIMANNKRVVMDVVEGRGVQGLVANPEVYNRRKQSNNNCNEEKKRIMEKGKEVEGVTPGPKTRKRRRTAASMEPDVDGYEPVETEHAQAAPSDGLRRSPRLAEQLENALADIDGVEREGLGDDEYIPLQGYSAVNGGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF90</accession>
    <name>A0A9Q8PF90_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11270</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765698.1">
        <property type="nucleotide sequence ID" value="XM_047910418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF90"/>
    <dbReference type="GeneID" id="71991148"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11270"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="64"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="29111" checksum="0A2EF569CF3DDC1F" modified="2023-09-13" version="1">MDAPRGVLQALGMVRNSSSEEATAQRAVAVSGNMPEDELSNDNSLAFPAGDNAILRAKTKRVLKRRECSICCDEVASNRFPKAPHKGANEHGRNVCFKCWEQHLHSQIDETDWDKISCAQCGQVLEEAEFEKLNASFTTDFYQKWLDKAARSCRESDEEFRACPNADCDWGCLMSTKADGNIFRCQMCKYRYCSMCGAPMHEDMTCEDYQAKLRREREEAIRQEEEASRAEVSKTTKQCPKCKSAIWKSGGCAHMTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFG5</accession>
    <name>A0A9Q8PFG5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09553</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 9">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765879.1">
        <property type="nucleotide sequence ID" value="XM_047908701.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71989431"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09553"/>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase UBR2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="12">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="8">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="412"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="488"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1428"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1307"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2136" mass="242032" checksum="A8163356E96BA275" modified="2023-09-13" version="1">MQSSPEEQLANHLAAQPANFDNRFTHSANCDLRQILFKSLAAQRQDYLRLFFPDGPPPDRSKPWSLSDAQGAIEGAEYTPAAKGTACGHIFKNGESTYHCKTCAADDTCVLCAKCFESSDHEGHGVLISVSPGNSGCCDCGDREAWKRDVKCSIHTADVNEEAQGGNVHGKQKASVGSLGSALPPDLVEAIRMTIARCVDYLCDVFSCSPEQLRMPKSQTSILRDERESRLEGVYGDEQQEQNLEYCLVLWNDEKHTVDDVQNQVARACSNTKRFGFQKAMEVNDVGRSIVHYSRDLEELLRMAEIIEQLKVTVTIRSARDIFREEQCAIIIHWISDIAGCSVGNEPYLLRNIVCEELLKPWRESSITTNKDIGRDGIDDHEQDENEKTQRKYRALLQPLRAAANVVRLEVEIQDPMDDDEDDNEDNDNEEDEEEEGDEFYMEVAEGPDDMDVEVGDLRRASEAATNSLDAADMDIDIMEENDELGEATIAGYPPPAPPPPRGERRTIFTPQDSDERENNEHQPPARRDPYPRVPATPKARFTRLTRPSKHWLEKPDGYKAPRPSEPCEDLWQRVRLDWLILYDLRLWKTLRIHLRHLYITTVVTIPHFKRILGLRFAGLYTTLAQLYLIADREPDHSIINLSVQMLTTPTITQEVVERGNFLTNLMAILYSFITTRQVGFPQDINPQATLAFDAGAVTNRRMFHFFLDLRWLFQSEFIHYRMRYEPRYLLQFLDLVKLHQGVCPNVRATGEHIEYESDTWISASMIVKEINKLCKQVAVSFEPHHKFDDGNASLQRAVRNVAQVTMINSFGYERKRFATAELKDDLAWHQIGPLVHDGKKYSVPRHAVQSEPMSFHHPLHYLLSWLIENAKGMSRDEMRSLLCFSPADLRDPWNATPKGGAAPSSLTGDELLSAIFEHPLRVCAWLAQMKAGMWVRNGITLRHQAHTYKSVSHRDVGYQRDILMVQAGLVLCGADDELPGERFLAQMIDRFQMDDWILGDYQIVPGYEESQQLDVFEDFFHLLVIALSERGNLQPHLGSEEQHARMLQHDIAHSLCFKPLSFSELNQRVTEKVGESDDFQRVLECMTNYRAPEGLQDTGTFELKPEYIELVDPFFAHYTRNQREEAENVYRKYTARKTGKKVEDIVYETRLEPIESGMFTHLAAFTNTPLFVQLAASALQFALHVKEAAPKVQVTRVETFLHMVLHLILLAVVEDRSGAEDGFVKLASSVTCNFAANSFIPHETATTLVSLLLSVGVMDDYTACHPAIKNVLRKMQMRHPEKLSAIGALGAMLDRGDSSSPASLSLEDKERKKQEALARQAKVMAKMKEQQNNFLQNQGMAFGDELDDFEDDMSITEEPEKVEHRKTWSFPTGTCILCQEETDENRLYGTFAFFGDSNILRTTPVEDPDYLDEVFRIPPSLDRSADNIRPFGVAGDNKRDVQRIGPDGKATTVERQGLSKGFPHQSGGNKGPVSTSCGHIMHYNCFEQYLAATSRRHGSQIARKHPERIDLKEFICPLCKALGNTFLPIVWKEKNCTPEHEVHAAKNLSDWLASVHEDYPVDYSFLNAASTAMQHHQQVSEIYSDRAAQYVTSMFAPTLIQNFNDLSLDNTTSPVSPTQARYPLRRGHTLSRLFGLNYGNNAATAAQSEIISHSAEMLRFSDLLSAYRRCEDSIKANKLIPVDDGVLRNDNPTVALSRALGMTITAFEISHRGMGNDPLATSLVSDFSEQNLTHLRILSETIESHLAVNMLRSGSSTIAKETIRRRDLAMAQLIGNGRDYDHDLEDHSFRLNSKLLFQDDIFLFFADWLALLGPNVAEANSIMQLCYWAEIVKVLFVLRPFFANQPFVPKPAEALPDRRFIDAVSRTNWGPGLNRFGLQRLVDLRQLVEKYALAFLRKCAVLMVVRYGLDFECPYNIDPSAPEIDRLTSLLHINSIDDLCGLYLAEDKSGHNLREITDRWIEQAHHVEDQGRGIIRTPHPAIYELVGLPKNYDTLTEAAIKCRCPTTGKEVQDPAVCLLCGEIFCSQAVCCMVEKNLGGCYQHMRKHGLKTGIFINIRKCMVLFCHGPGTGSFAHAPYLDRHGEPDPTLRRHHQLFLNQRRYDKLLREVWLGHMVPSVISRKLEADINPGGWETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFX5</accession>
    <name>A0A9Q8PFX5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-type lectin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09243</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766116.1">
        <property type="nucleotide sequence ID" value="XM_047908391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFX5"/>
    <dbReference type="GeneID" id="71989121"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09243"/>
    <dbReference type="OrthoDB" id="10265193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040388727" description="L-type lectin-like domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="26"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="441" mass="48574" checksum="4A6815E4F1D19740" modified="2023-09-13" version="1">MVGRIPQRLSWLLAAGLASAQYDVDSLTFGKSGVISPSGSGIPGWQASSVNHQVQMLSDRVILTPPVPGNAKGSLWADNTATSSDWSASLDFRASGQETGSGNLQVWYVSSKEAIGTNSLYNVGKFDGLVVVVDQYGNSGGKVRGFLNDGTQDFNRHPNVESLAFGQCDYHYRNLGRLSTLTIRNNNGLTVLLDGHECFSSSKIILPSGNYFGISASTGEQNPDSFEIHKFHVQAGLAGASTQQQTQPQGGQQAQQPISNKLDSFPDAPHAIPDRDAEDFKTQTSQFEDLHNRVQGLQHQLANMFMEFKAISDKLDKKHQEVTQLVQNMQGSKETGIPPELVGKIQRMSEKVDKMEETLNTVKNDVEGKDYRQHLNNLNTAISQLHGGLREDLPDRILDIVRRHSPQFGWLIFAVVGVQLSIVGAYFVYKKRRNSMPKKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG11</accession>
    <name>A0A9Q8PG11_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766295.1">
        <property type="nucleotide sequence ID" value="XM_047908671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG11"/>
    <dbReference type="GeneID" id="71989401"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09523"/>
    <dbReference type="OMA" id="FATHHEI"/>
    <dbReference type="OrthoDB" id="3021074at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="55610" checksum="087737F10F759FC9" modified="2023-09-13" version="1">MPAIVNDLADILLWNRETTPSNVSSANTTSAPALQVICAWPVSGQYGPGSRVLYYVLVAACIFAHKVEWLRNACLAAALIFPVVAAIHGIVLAAVHIDGAVDMDVYGAFQLCTIGVLAAPVTVRLSRTYFEDPGRNIIFVWSTIVLAGLLSLTIEFYRLSSVGCSHDDLGGAISIDPTKFPYENATCKLTCTVDDGPFSPIRGGSANNIYVIPSPTKLTFNAATLLAAACCIPAILLLVSMWIKILEINWRRQSGAQESLGEVKDNRFIKHFRQYAPVLIFGPATFAILIVGEINLFSSQVRYQTEPIANIGQWAPIAGTSVAVLGSLYLLIADAMAQERQALQQKDSDSGEEVSYPGSDYAPVRSVVRVFLKIADYISRPASGRLEHDREFRTGRAQEYPNTPGEEFQNRELSRIRSLYGGSQRDSDSIRSGISRHSRHRSDTVSSGDGKGFATHHEIAAEPTQPICTRRRQDTSDTLEVPSPVLRSTTQRSIASSSTPPPIIRIETLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG93</accession>
    <name>A0A9Q8PG93_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766299.1">
        <property type="nucleotide sequence ID" value="XM_047908192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG93"/>
    <dbReference type="GeneID" id="71988922"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09044"/>
    <dbReference type="OrthoDB" id="72726at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31899" checksum="F3DA503F5AE5E515" modified="2023-09-13" version="1">MTAAVPLPQDEHLSKKRRRGSGDFGGEHLHENRHTTWPIEDHHLHHQARDHRGNSEDSIRSRQIAATGNLPTQSKSSKRQIVTLTTTTGRCPLLELPAEIREQIWMHTVTEWTAATVETLRLTPTRSVRLLHKRAIRMDRFNRPPPPALARASRQLRAESLHLYYQLNVFECWRPLFWLKDWSQSTFIDWLVSLGPVQTKWLRNIVLLYKHENELEHDVEEVLTAQGFELQPGVVSNKQELSEYEMCFEELGLPRHFGRRRRWDRWMAATAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGD5</accession>
    <name>A0A9Q8PGD5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trehalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766300.1">
        <property type="nucleotide sequence ID" value="XM_047908191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGD5"/>
    <dbReference type="GeneID" id="71988921"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09043"/>
    <dbReference type="OrthoDB" id="406733at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="105"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="28338" checksum="95ED6F46DD49E3BA" modified="2023-09-13" version="1">MPPDSTDDMVRRPQIMSPAQRENLDELDPLGVRANTGYMPVEHYGLLGTMHTSALVATDAGLDFMCWPNFDSPAVFCRMLDKDRGGTFAITPRARHAKGILTTKQQYLQHPEALDSACLIAPLAFFFVASNDPRFTNTLNRTLKSPDQGGLTSNGMVYRYNLHTSNDGLAGDEGAFSMCTFWMVEALTRAGAYEEQYLDKAVTLFENAPGYANHLGMFSEEISKSGEQLGNTPQAFSHLALISAAFNLDRVTKGHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH14</accession>
    <name>A0A9Q8PH14_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766669.1">
        <property type="nucleotide sequence ID" value="XM_047908357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH14"/>
    <dbReference type="GeneID" id="71989087"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09209"/>
    <dbReference type="OrthoDB" id="6161812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056681">
        <property type="entry name" value="DUF7779"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25000">
        <property type="entry name" value="DUF7779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="226"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7779" evidence="2">
        <location>
            <begin position="480"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="61375" checksum="1FC2096B218F4C39" modified="2023-09-13" version="1">MAHSLAGFILKQCVVVADAQKDRFRLLREALAGIVLMGCPHATKEARRTELYNKSNDILRLSNLGRRVKDRLQYGQELLNTCRRFDDVCNDTNILSLHEQRPTRVPVRLGSSAQYLVGKRMAKIDSGKPEVLTSIDSDHRSLPSLEDDQAPLKLDEIAFRELKRILSMSGRSSFDNAEPVMPGVVTRTPVALEPLIQAFVKPRLPNLPFFELNISRQRTKDFHGREEVLEKLDTQLLSGPNMAILYGTGGFGKSEVALEFVHRRRGRFDAIFWLKADNLSKMRQDFGRFAAQLGLEDEGGATDPFTSREMMKTWLEEPIQAPNKSGRQVATWLVVFDGADDLKVLNEFKSIYGKGAILVTTREADSVEILSADMPTDSVSASLFATKMHTFGQDEAVDLLAKLVRLNMDDEEEHQSARQIAGILNGLPLAINQMAGVINSQHLTLSEFCERYQDIDTRGLRHHGDSGRLGSQSMISSMRMALLSPQAIALLKIFVLLDPDCIHENLFDNLADADIVFTGFPATQAEFVKSRNELLQAALVQRNGARQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH39</accession>
    <name>A0A9Q8PH39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766676.1">
        <property type="nucleotide sequence ID" value="XM_047908353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH39"/>
    <dbReference type="GeneID" id="71989083"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09205"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11252" checksum="36DC831A7DFC0A17" modified="2023-09-13" version="1">MEARPNYRDDPPSSPLEAPVAWDQLRLSPILEAPELTLSIGQIPYRSRITGVNEILPVGASVVGGPGTDLSLIETAQTVLRYSGRPLCVATGRQMFEDDYQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHF4</accession>
    <name>A0A9Q8PHF4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Decarboxylase orsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11864</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766947.1">
        <property type="nucleotide sequence ID" value="XM_047911012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHF4"/>
    <dbReference type="GeneID" id="71991742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11864"/>
    <dbReference type="OMA" id="TWASEDM"/>
    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000099">
        <property type="entry name" value="Amidohydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="74"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="37015" checksum="29014EE286970694" modified="2023-09-13" version="1">MTPPLIALEEHFLSTAVLNAFDQAYQEQFKAIPMAKEKLSDLDELRLSEMEKGKVWLQVISHAPAPGGASLDQCRSGNDELAAAVRKRPDRFAGFAVLPVADPAGCAQELERTVKELGFVGALIDNHVNGTYYEGPEYDVMWQKAQDLDVAIYLHPTWPAENMMPQYTGNFSGGASRSLGASGWGWHTETGLHVLRLYAAGVFDKFPRLKIIIGHFGEMLPFSLQRICNLSVRWGDQQRKLKQVWDENIWITTSGVWSLDPMRCILGNTKIDHILFSVDYPFEKNENGLKWIEELEQSGLVTQEELEMIAYKNSEKLLRLKAPHIANGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHG5</accession>
    <name>A0A9Q8PHG5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766899.1">
        <property type="nucleotide sequence ID" value="XM_047911377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHG5"/>
    <dbReference type="GeneID" id="71992107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12229"/>
    <dbReference type="OMA" id="HCNICPK"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="603" mass="67416" checksum="79EAE68443676FD4" modified="2023-09-13" version="1">MSLLAQDASNIPLHCNICPKRPDFSDVSHLLTHIASKGHLSWYFRTKVKGSTDASSQKVIDDYDEWYEEWDVATLMQERMSQKEKKRASGARRVDTSRRGSGASTASNSARNTPVPSGRGQRQQRLLRHNLHMLDPQLNRHQMADPMSRSGTPHSHFSFDRGMNHPYAPPIGNFAPNGMNISFSGSGSNSPYVKQESMSSFSDNDDDDDDDDDSYVVEPRPRRPAARRRQHNGSGSLGSLMDDDASVDEMPNDETKLKGIRWPGMDIFDSATAEMRRKRNQKKHASVLRSLQATSEVVEPTESVWDTEGILRKERLITGSPASDDSLIEGESEPEPEITEKKRTRRRARPALVDKDVNTGRILRNRGQSHHPPFGRSTRAATVMKIEDEDDDLTFAPTRQRKRTGFSIHRDNSGPDITFDNPPPMNYLTSGFRNPFQQGNQRDNLYRQYQNDMNVPRAHGRQPSWGNVNGTFRPTSGGNNAMPNPGLANFGNFLNHQTVSQQSGAPTSHHAPNPFQQHFSFGPHPMQTGIANPMYQPPNNDPFAGLFDINPLAMDLTFPKIEGGLHAQQDMAPANPLFLSSNPIKEDDEVTISARDSVTGEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHL7</accession>
    <name>A0A9Q8PHL7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoporin NUP49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11939</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767165.1">
        <property type="nucleotide sequence ID" value="XM_047911087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHL7"/>
    <dbReference type="GeneID" id="71991817"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11939"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="3" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="497"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="566"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="621"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="679"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="692" mass="74329" checksum="7F9497E7F5B709D9" modified="2023-09-13" version="1">MAHNISKEEYEARCHEIASLETVLARMRSSLDDVTVTRNSSGGGGFGGPNHRAQSRFSGGALFGNETRMHQASGSGGLFGNSNQAYQASGGFGFGNSKSYEPPSGGFGSGRYEPYQASSGFGNSNSHQPPSGGFGSAPRSYQASVGNDFGESKSYQPPSGGFGSAPRSYQAARGGGLFGNSNQSQQAPSGLFGNSSAQSGSGLFGNDNNSGHGFGGEGLFGQARSSAGRLFGNSNGSPRPASSAGHLFGNGSKATATGGDFGGGLFGNSNQAHQESGDERLFGGPFRPSHGHATGGLYGNSNSGRTFGSGNGAGGGGLFGEASRHSQGTRGDPLFGFRPTTSTGTSLFGNNSHSYPSSPPSSSRERGEPDVDEYHALLKRYGLNESDVGTFRENYPAGEIHHAELRKKLWLSHLTSEEVDRWNSFAHGQWSADDARKYDEFGRERPRTMEDFRKRLSREQEVFERYDREALKSWSIKSLFGNRPDGLTFYYGGQESGARSKNNGYPLSPPFGSKGTGSGSSGADVKREKKFQGLEASMWATDEPLPRSRPEGGAPRPDSYWDQDDSDRPEGSFGRNQRDRSSGRSRAERSQRSEDKRPINFAQYESDTDTDDTAYRTKKTAQPERQEKQNDQAKERQENAREEPQAKEEQNVLSLEDRVKRVANTKFGSIHGENTGGKDNGEGKGHGKLEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHQ1</accession>
    <name>A0A9Q8PHQ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_12076</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Its motor activity is directed toward the microtubule's plus end.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767061.1">
        <property type="nucleotide sequence ID" value="XM_047911224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHQ1"/>
    <dbReference type="GeneID" id="71991954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12076"/>
    <dbReference type="OMA" id="FPMGTKQ"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="6"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="380"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="679"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="881"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="772"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="904"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO22695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="927" mass="102862" checksum="C779D3EE88D7E315" modified="2023-09-13" version="1">MSTANTIKVVARFRPQNKIEVAAGSEQIVNFNSDDSCTIESREGSGAFTFDRIFPTNTPQQNVFDYSIRSTVDDVLAGYNGTVFAYGQTGSGKTFTMMGADIADDSLKGIIPRIVEQIFSRIMTSDGSIEFTVKVSYMEIYMEKIRDLLVPQNDNLPVHEDKQRGVYVKGLGEFYVGSVEEVYHVLERGGQARAVASTNMNQESSRSHSIFVIEVTQKNVETGSARSGRLFLVDLAGSEKVGKTGASGQTLEEAKKINKSLSALGMVINALSDGKSTHVPYRDSKLTRILQESLGGNSRTTLIINCSPASYNTDETISTLRFGERAKTIKQKAKVNEELSPAQLKAMLKKAQSQVTNFESYVQSLEGEVLNWRKGEAVPKDKWTPRMSDLSKPSAPPRSETPTSRVKSMSDTPGTPRPESRLDLDRASTPSIPLEKDEKEEFLKRENELQDQLAEKERSLEAAEQALQAARNELKDMRETHSSTSRANEKLQGETESLRMQVEKIEFETKEASITMDSLKEANAELTQELDDIKHQLLDAKMSAKESTAILDEKERLKKERMAQMMAGFDLGDGMMSQSEIQVREMVQQVQSLLEIADSGETVPADDLHALKERLLDTQSMVRQHDINAGSSHVEGAHGAILEQKLAQAQRDYQELLEKNLSEADVEEVKRNLFESLQSQQNGGADSAEVQETLSRQQEENARMRHELEALRKQTLNGSNGATVSKQLADFDTIKKSLMRDLQNRCERVVELEISLDSTREQYNSILRSSNSKQQQKKLAFLERNLEQLTMVQRQLVEQNAQLKKEVAIAERKLVARGERIRGLEGLVQESQEKLMLANHKFESQLMAVKERLEAAKTGSTRGLGAAPAPANGPFANNPFGRIAKPLRGGGGGGDGPAVPTFAGLQSSASQESSGNKRSSWFFNQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHR4</accession>
    <name>A0A9Q8PHR4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767112.1">
        <property type="nucleotide sequence ID" value="XM_047911259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHR4"/>
    <dbReference type="GeneID" id="71991989"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12111"/>
    <dbReference type="OrthoDB" id="4115400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="577"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="991"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="848"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="764"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1058"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1160" mass="129431" checksum="4ED00832449A2852" modified="2023-09-13" version="1">MDCPSASMSMSLSSPRRRRPFEDPHSVMVRTGSNDSSKSSDDILVAGPSHTPSQRNKQAIPPHVIQSSHSRRSSAKLTTARVVYDRFTISFGPAIARERFRGIVRTRPKPLSRASDSSSSSDVKTEDDELSGGPNHRGTYSKEYTLLHPNITWVHRGQGRYLPASAIATDNTSSSARPTRQTTERTNGSVATSEQTMESMTQALYDHFSDWRKQRNPEASDRWSPQLKGQYKLYLEMIKTTPRQQWLKAIETIADQDHREIVRQWNRAMDRQFPTNGKIERQHSEDGSPRNHLSRQAKTFWPSLEHRRSSRLTDAPNNGSYNEDDDYGAGDTDGSHSPDKTYRKDHVDAHPNELFHHAGNGWWKRGPRPNDSEKTSDRRDSSASHAIKYSSSEASRESDGGATIHKEELYKYPGMTFHHKGNRWYKPGIGPSGVTGCITVSADGQIIGPKRRRSDFTVDSNEMSIDAPPPLSTPDLGHTVNKAYADLHPEVEWVHRGGGRYKRKASLIDTGTVAPAGSSDRRSSRAENSFSNHYAASRASDELRRSSNRRRNSKLESLDDEPGELFDKAYVDAHPDEKFYHRGQGRYARGDRPKAMGGPSLDHSHSEEKFDKAYVDAHPNETFHHRGQGRWARGLPPPHSNSKTAVRGPGALEMYKREKSPQDGPKPPPLTALLKKQEGPDLWRNLNWQYRGGGKWCQVSKEEAHRLTTKSRKPRVSSGRSRGDEADMQLRGEAFAVDGSSTAAAKRSAGLLAKPPKIIRKRSQQSMAQLPSNSHSTAPTPRPALLPPEDDRVDQEDLPSLYKDAWSDAESEDLDDAAKILRSEFDPMIGPEPFVRALTKHDPAVRSLDTLKQLAANAQQALMQLQDEYLALDEIVARHPMNGKKERKAVKGGRQPLEYTVWEDKKEAILYDYTFDPRKTGYQNPDAQRIIRDEEGRELRRRRNRYGHDPHETAVNYGDGEMTAKRAVKPVSRFDGVVIPPPRKRSRLMTTADDNITKTMDDSPSATPNRAASPIPGFTEAEMAAINDPKRGRWRGHVPKVMHQAMHHRLRELRAESVGSQRSESGTSTGSPNQTGARKGRPPGSKNLKPRKDIGIKKGPRKKLATSQATPTSSVEPEMMQDGSVPAIVENPPDDVPAAAAADEPMAIDAAASQAMSLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJX6</accession>
    <name>A0A9Q8PJX6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768146.1">
        <property type="nucleotide sequence ID" value="XM_047912460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJX6"/>
    <dbReference type="GeneID" id="71993190"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13312"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="42941" checksum="FB40F7FF75746E41" modified="2023-09-13" version="1">MSIAKSRPYRFVVGPKREAYFLHPKLVSLHSGYLGALIDADWSGERTACIVLDDVREDTFASVAEYLYTGDYTSASYRVTVIEDDSGDLDSDMIVTPPTTVDGHDADSRLRSAQKSGQAKTALAERPITQGVWEFSGPNHSPVEKSKEKDVSDWDESNPELMTKESPVSPVVDLDEWASYTMKSMKVKAKKRAAMWAEPEPTLEPEADELFTTPGLRACSPINETSEARHITPSAAKPTREAAMWTAFTARQYELEHRPTPVAVRANLNADEGYDVVFLSHARIFMCAKAWFIEGLAKLALKRLHETLTSFTLYSERVGDVVKLVEYAYSRSCMGCVGVLDLRDLVMHYAACKIARLVSDQRFQGVLQAENTAGVDLVKELVEDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK48</accession>
    <name>A0A9Q8PK48_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768304.1">
        <property type="nucleotide sequence ID" value="XM_047912387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK48"/>
    <dbReference type="GeneID" id="71993117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13239"/>
    <dbReference type="OrthoDB" id="3815501at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13002" checksum="8976458AAFDCCE12" modified="2023-09-13" version="1">MAMLRNPSYSPVGQWLVPPAFRTSAALLRNLPPPVPRHRRRSITNATKTDYIPSLLAVPRVAAKPGGWHPTLIHSSRDIKFTVIRLAPGQGEVPTHWHSHVWNYFVPLEGEAVIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKH5</accession>
    <name>A0A9Q8PKH5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768472.1">
        <property type="nucleotide sequence ID" value="XM_047912321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKH5"/>
    <dbReference type="GeneID" id="71993051"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13173"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="350" mass="39925" checksum="75E64A96B422DCAD" modified="2023-09-13" version="1">MSSTAHFFSFRSASITRRLHPQTTLSHDNHRSYQNTDERQQDHETINYNHDRRNSREAIPLHGPPPPELKNRIYSMLLENDTNVEISSHDVGPLCITTIQAAILRTCRQVNNENCVLDLLSCPDFIHIHQNTDLTQHRDTISKKVLVRAEYIVSPANMTNTAAEIATEKPFRFMDLPPELRNRVYSLILENDDPFILGRAFWATPVVHTAILRTCQQVRSEATSILYGNNIFGPNECMLAPFLEAIGPSIKHIRTLWAGSLLTNTQTQKFFTLLKGASLAKTVGPLFRCLHKNRKREPGYKVKDVLDVLVVYVAVNHNLKVPTENFWEKAKLETEFYGKKVKELVGATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKT6</accession>
    <name>A0A9Q8PKT6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768696.1">
        <property type="nucleotide sequence ID" value="XM_047913031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKT6"/>
    <dbReference type="GeneID" id="71993761"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13883"/>
    <dbReference type="OMA" id="GCQVYRT"/>
    <dbReference type="OrthoDB" id="10452931at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040248632" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="24377" checksum="794EA83EF9E92B75" modified="2023-09-13" version="1">MRFSITTLSLLALFSFVSAEANAIPNADPVAEPNAAPDAEANTNNLWNAINGAAKAKQAAALNLKNFGMFGAIGFPKEQTWRQKCKKKNPKIEHVIAKFCERGTGGKGGVTVPNKYPSGGMCTNIDPKAANHAPDGKGNPHVKKQVQWCTKIGSKKKKCKPFRISKDMCMGKLFQVCAKGDNEGKGKAAENGGCQVYRTGKINYSNNWVGVGRNPFYDGWTAAGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLH3</accession>
    <name>A0A9Q8PLH3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DENN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912803.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PLH3"/>
    <dbReference type="GeneID" id="71993533"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13655"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
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        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
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        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF21">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03455">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="UDENN" evidence="6">
        <location>
            <begin position="227"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="5">
        <location>
            <begin position="899"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="196"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="715"/>
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        <location>
            <begin position="800"/>
            <end position="842"/>
        </location>
    </feature>
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        <location>
            <begin position="1073"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
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        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
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        <location>
            <begin position="728"/>
            <end position="743"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="4">
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            <begin position="757"/>
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        </location>
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        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
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        <location>
            <begin position="1125"/>
            <end position="1135"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1135" mass="125900" checksum="A37D11B63F989E31" modified="2023-09-13" version="1">MAPAKPSNNVSSNGDTSAPLADYFFIAGIESTQVYDEKVQAAPPAAPVEDTIDEDRELEIDNVNGGRPTTPGSPTETVQRRSRYSFEARKSIGSIINGLDEKIPSSNRSSTTIRAVQIGAGALDDDAFEEALKKFATERDSFLEDIHVQAGTVTSHNPQKRPSHRPKTVRINQDENNLTANGLKSGVGSLRRRLSTMNSMKRASSRSSVRQSKRLSGYNSVIPSPQPFQTPADMHPLQRSYEPVLLDRYPTKTMVDESKRRTPFPDYVPMFTFPNDVKVVTSDERPRSTWHGFAMTNSDNSKLYGVTVTIWVPLNNTASDALEQQCEQWRQTNMRPEERELANSLGERLSSERAKLSRLLAELPSVESESDEREQLEEEIAAVEEKIGLMNDLLRPVRHGAASKIDGLTEGDTGFWIPRAYGVLGKDANMTSFWKEWLKAIIVPMTNGAILRVPASSPKVGLWQPLERYVCNLCIEALSPITSITQVEVAIRDLRLYARKEAINELPGSRNNDLYALFRCLTIPNIITLLEFALSESRIVLVSSHTAMLQLACQALTSLLYPMKWSGVLIPVLPYRLIQALEAPCPYIAGIEKRYPTWQDHMPDDDYCMVDLDKNEIHSTEQPISLPRPQRRKLQALLQQAAPHHLRFGVPVGPPPYAIETYPCDMFSSENPQVFTSKAAPTTLANYVSESSTTFGDATSLPSVSKQAVFNAFVSQRPDSAHRHNERPSTSSTSKNSQSSSASPPSPTTTPSPVSTNFPLTPTGVSRNDSGFALQASLREKRSGHFTDGLSRRNSAVTSLFNARNPFQDKTNTQTQLGPDRMNTVRRPSAPLPGQQSAPVLGHHPSMSTSTLGGTTLNGAGSTYAPSIYAPSTMAPSTIMQPQLVQRVQDTDTTKWVEGHCLQRRRPDTKTYCTICDERCDDEVFKCTGCGMTIHGRCAMATCIVCPVAFRADQVRAAFVRCFASLFYTYRKCMQHASGAHRKQGMVYHFNMDQFIKSVPHGDSEYMSMLRQTQAFNEFIHERESTRAEDPSIKLFDEIILSKRNRGRSSFFSKSHTSFLSDTSDHLWRSAAATLPNGRPSDTRASAGRTPAKLDPTLMKEPRSIQGAPRLGQAKTKRKPVASMLINTQTLSPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLM0</accession>
    <name>A0A9Q8PLM0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sexual development protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLM0"/>
    <dbReference type="GeneID" id="71993447"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13569"/>
    <dbReference type="OrthoDB" id="5293813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040501905" description="Sexual development protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="42179" checksum="0DC786B8C5BC0D61" modified="2023-09-13" version="1">MYTSTIASAAVLGLATISIALPTQKTTNSSLIATTKSSSSASAFKFPLANGFPDIKNPSDHLTQIQQDALGTLPKAAANAPKGAKPQPDSITSLGFIAFNELFEVAFFTDLITNITTSAPGFGDGDLEILGQKKDDILKILTTVLAQEELHELNANGAFETLTGHEIEPCQYIFPASNFRDAIRLAATFTDVVLGTLPDIQTIFANDNDNGLIRGVGSVIGQEGEQNGFYRQILGKNPSALPFLTASARDFAFSAINQNFVVPSSCPSLDILKQGGLKIFDVLTVVEAPAEFEPKNQDLKFSFKTSQTNVAAPKTNSLVAQQNFLTYVNQQNAPVSVAIEDQSIGDDGAIHFTAHFPGADNEMNGLTIAAITTGKDFVDVDTVAKATLFGPALIEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLN3</accession>
    <name>A0A9Q8PLN3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_13997</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769087.1">
        <property type="nucleotide sequence ID" value="XM_047913145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLN3"/>
    <dbReference type="GeneID" id="71993875"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13997"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001834">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF152">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="36"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="260"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO24721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="485" mass="55426" checksum="F96CB50624F41C9A" modified="2023-09-13" version="1">MPGPPARKLGQKVDIDFTLRKVFGRDSFRPVQREVVIAALDGHDVFLQAATGFGKSLCFQLPAVVDYGITIVISPLLALMNNQIASLRAANIRVGTINSTTPMSAKNAILDDLKTGHPLTRLLYVTPEYCQLDHFRKHLRIVHQQKELARIAVDEAHCISEWGHDFRPSFKELKWFKEEFSEVPMICCTATATKQVRDDVIKTLALNPDTLKSYTMTTSRPNLHIDIRFTSDDVDRYDDFLKWIKNVHARRADNPTRSQELRQRKERVTSFPGIIYTWYRKDTEALAARLQSDGIGAKAYHAGLSVEQKDDHLHGWVQNKEGYDVIVATTAFGMGIDKDNVRFVAHWQMPKSFEGYYQEAGRAGRDGKASLCIMYYSREDRDRAAFVMRREAEKTYNKQGQNRDAQILRGKSLQALIGYCENVNGCRHKLIAKYFGEKEAPPCDYACDWHKDPVTLARRKDQDLSSEEWIATQRQTGTYDCEGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLW5</accession>
    <name>A0A9Q8PLW5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769196.1">
        <property type="nucleotide sequence ID" value="XM_047912851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLW5"/>
    <dbReference type="GeneID" id="71993581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13703"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="49193" checksum="DB08BCA97DF8EFDB" modified="2023-09-13" version="1">MPSGATSQVFETVELLEMILLNISIKHPEFWRNEAGLRQLFAVQRVSKTFRDTIQGSSKLLRVMFLKHDPTSEVFDPEVNDFQSIATSNPFACSAYLYTTRGAGVKTSFMAAQGSEDGMQIIFEQGEAERSFLWKEEQYGVTPSWKKMLLKEGQPRPLWLELNWRDSDGATANQFNSMVDDQLPPGCTLGELVEYLSTIAVPYRERGGQGVDWYRTVAGVKVIEKLKAKTVELLEMIFLHTRAKATYSMTDVYEEARNLRHLFILQRVNRTFRDTIQGSVQLRRAMFLEEYSAAAEVTDEDGDHEHKLINPLLYSDCFKLTNTYFVEVVWDACKSNKLPIHYHCPDQNTSSKTPKLSIDQEEVSWKSMLLQQDSYKMLWLKFRGWDEYGRCWQPFFEVEPVLAPRTLGELITLLHSKKPQYEIAEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMH6</accession>
    <name>A0A9Q8PMH6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_14248</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Prevacuolar compartment membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769522.1">
        <property type="nucleotide sequence ID" value="XM_047913396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMH6"/>
    <dbReference type="GeneID" id="71994126"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14248"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034499">
        <property type="term" value="P:late endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051074">
        <property type="entry name" value="Sorting_Nexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963:SF2">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="14">
        <location>
            <begin position="70"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO25156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="21989" checksum="C97BC15E85273F2F" modified="2023-09-13" version="1">MQRIDPRPVDTPAQQQAQDQQSQGQGQGQEQNGSTRQSQLNLPPGFSSTGREPHTQSFEEIYGVPENFLEIEVTDPQTHQPSSNPNSRYTTYLIRLSTNIPAFKLRRSEVRRRYSDFEVFRDLLERESARVSIPPLPGKVYLNRFDDAVIEERRRGLERFLKIVVGHPLLQTGSRVLGGFVQDPNWDRNAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMV0</accession>
    <name>A0A9Q8PMV0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="61"/>
            <end position="91"/>
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        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
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        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="49872" checksum="576C960C2EAB42C3" modified="2023-09-13" version="1">MDRIGSGSEATANGALHEHSAQDSQHSHGSARSHGSRSSRTPTPARESKKPRAPHTKSRQGCLRCKRRRVKCNEQRPKCRACQIRNESCKYPDLVACSTCLRTDCICFNDPIPPAQQRADDSAVDFEFIYHYGRFTYDTVAVEPITENAKPLFQPPACLQHPFLMDLFMALAATHLATSNPAEASKYIVHAIRYQNRAFGRFSGVLVDPKVEDCLPMFLFSAMLGILQLALSRVPRPTDQSQSIPPIETLLELRRLWRGSKSILQHSRGIMSSENYQSIFDDDEAPRREHLKTPVSDKDLQGECYGPLNDLLNLVDATFPTDSTSFPIPIQEIDPAAVSDDEACKLAVAWLRRITGLHLSSRPAQLLAWPVVIPEKFLHLVQAENPRAQAICACYGFLLRRLNDRWWAHGFGQDLILQLASPRNRAIYAEFYRRLFESAMTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQE9</accession>
    <name>A0A9Q8UQE9_PASFU</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UQE9"/>
    <dbReference type="GeneID" id="71987631"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07753"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="71" mass="7957" checksum="9702AFBE05665643" modified="2023-09-13" version="1">MAPRTRSATKAKKATRKSRAPTYYGSDGESELELYSDDEIADDEDEEDDADYVDLFAGRTKAEIISSKNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR83</accession>
    <name>A0A9Q8UR83_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate-forming reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763817.1">
        <property type="nucleotide sequence ID" value="XM_047905981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR83"/>
    <dbReference type="GeneID" id="71986711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06833"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
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    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="652" mass="73217" checksum="CD1EB6E87D32E6AF" modified="2023-09-13" version="1">MRSRRAESAAVACPPSLRDAHTRRYTNITPYQESPWLASRLCLATMPQPTTADTTATEQDHIEGSGPDDSILATHNNPCQPSSLERPASAQSTTSETRTFDENLEAGIRLPEVAHIYGSSSWITLWPSRHKLVNSASSFSTEETYTEKIEPPERVLDICDTRGLGVKAVTFREDEKIITSIVTDAHPEPEFSEKIATKAVIDKMLEEHPLPLVTGPEWRNRFRHGFLSMYRRLHIAVLLANLIALVYCICQVAKYGYSHYAYTDASNAVAANLFVGTLMRHEHAINLFFRICTMLPHSTPLAIRRYAAKVYSYGGIHSACGISSLFWYVFYVVLLLKQFGGYGEEQRPLLHALQALTGVMLALFATLIVMAYPTIRSRYHDWWELSHRFAGWTAILVIWTQTVIAAWPIADILDTNVGMILVTTPAFWFLLATSCMIIYPWTRLRRREVVVEPLSERATRLRFNNRKVTSCVGTRLANSPLMENHAFATIPNPDNKMGYSVIISNAGDWTSKIIANPPSHIWMRGAHTMGVSRIGLLFKPVILAATGSGIGPTLSFLQAYPHWPCHVVWSATYPEETFGKEIMNTVLRADPKAVIVCRKMTGRYAMHELACAAYRRFEAEAVVLISNPMETRRTVYELEARGIPAYGAIFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URC1</accession>
    <name>A0A9Q8URC1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URC1"/>
    <dbReference type="GeneID" id="71990252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10374"/>
    <dbReference type="OMA" id="QRARNSF"/>
    <dbReference type="OrthoDB" id="10344595at2759"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="22833" checksum="29A57E746A0533CA" modified="2023-09-13" version="1">MWNFISSHRPSRSQDWAHFNIERNIEKPRGSIERQRIDPLMDECGTDERRYYRSAEFQQALLEAKIERDLASVESPIEDNKRQSWHRRSSTIGRMNTRASQSASSLPMFDYEADRIRQLEEARSEQPPPDVELPSPGGEAVAPPEHVPDLNRDESTDGSNSSEQSHQRRRSRPRINKDGLAPLFQRARNSFYGGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URF1</accession>
    <name>A0A9Q8URF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764013.1">
        <property type="nucleotide sequence ID" value="XM_047909521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URF1"/>
    <dbReference type="GeneID" id="71990251"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10373"/>
    <dbReference type="OMA" id="MTDGHSA"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="481" mass="53391" checksum="FFF94625BA2B783F" modified="2023-09-13" version="1">MATTNTSAPNATTATFDHAANGNEKLSPGIAAGSVPPSSGRSSGQQKDEEVLPAGLFHQPTHHEVDIEDYFRGPRDVNRHSKWPSFMRMHGSILPKMIVPLSFVAGWATLIVCVSRLVHPIEIQSTLLTVLGFVVGLALSFRSTTAYERFSEGRRYWSMLILTSRNLARLIWVHTRERHDVSPDLGKSDLLAKLAALQLLNAFAVSLKHRLRFEPSTDYPDLAPLVVNLRTLAGEADQTHLHQRKHSRVKSIGQYLGIPMAESNPRKLLKKSKENLGNTPLEILTYLSAYAEEIMQNKTLSIGCQQSQIMTLLATMTDVLTNVERVVNTPLPVAYSISIAQITWAYVLALPFQLVTYLDWVAIPGTIIAGYIILGLAQIGRELENPFGMDVNDLPLDQYCSELANDIDALTSMPAPLNVEAWTRERGSKVLWPLSQMEYKAWQNKTVPEIRAALRAKAASRDVKKDRMNTFVESVGLTSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USF0</accession>
    <name>A0A9Q8USF0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pre-mRNA-splicing factor syf1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_10972</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765135.1">
        <property type="nucleotide sequence ID" value="XM_047910120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USF0"/>
    <dbReference type="GeneID" id="71990850"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10972"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000666">
        <property type="entry name" value="DNA repair and transcription protein (Xab2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="15">
        <location>
            <begin position="49"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="13">
        <location>
            <begin position="210"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="14">
        <location>
            <begin position="430"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="813"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="813"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="858"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO20769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="867" mass="100368" checksum="265F609F65F6A946" modified="2023-09-13" version="1">MPSSLSLPFSLVSRRKSSENTSTATLTTAAMADRSHPQQSFLYLISQNDEVYENDILRNPGNIKAWLDYAHYKRQYGTLLEQSFVLERACIALPRSYKLWKMYLETRVRHLKGRSPAKWKPEFQKVNALFERALVLLNKMPKIWEMYLEFLCQQPLLTFTRRTFDRALRALPITQHNRVWALYRPFANSAGGDTAVKVWRRYIQLHPDNVEEFIELLVNEGKYTEAIQRYIEILNNPRFKSKEAKGPFQHWTEMLEILIDHARLVPNPIPLANGSTLSVETIIRSGLERFADQRGILWVGLARYYINLGTYERARDIFEEGITTVMTVRDFSVVFDTYAEAEEALISIKLEDSAARQQKGRVDEDADLDLDIRMLRFEQLMDRRPFLVNDVLLRQNPHNVNEWQKRVALWSENKQMVVQTYADAIAAISPKKAVGRFHELWTNYAKFYEEGGDLQNARIIMEKAVKVPYKSVSELAEMWTEWAEMELRNENFDQAVNIMATATKAPKRSAVDYFDETLLPQQRVHKSWKLWSFYVDLVESVSSLDETKKVYERIFELRIATPQTVVNYANLLEENGYHEESFKVYERGLDLFSYPVAFELWNLYLTKAVDRRISIERLRDLFEQAVEGCPPRFAKTLYLMYGALEEERGLARHAMRIYERATRAVADEDRTEMFEFYITKSASNFGLTSTRPIYERAIAALPDKEAASMCIKFAEMERRLGEIDRARAIYGHASQFCDPRVNAEFWRKWESFEVQHGNEDTFKEMLRIKRSVQAQFNTDVNFIASQAVARQQAAEAGADEDGMDAEGMGQEKADAMRNLERQARAPMGFVAASSGPEGGNRPKPQVNGDAAQAKLANEDEIDLDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USX1</accession>
    <name>A0A9Q8USX1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucoamylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11219</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765588.1">
        <property type="nucleotide sequence ID" value="XM_047910367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USX1"/>
    <dbReference type="GeneID" id="71991097"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11219"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048:SF0">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040442002" evidence="4">
        <location>
            <begin position="24"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="5">
        <location>
            <begin position="68"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="980" mass="109097" checksum="4A352855091F2929" modified="2023-09-13" version="1">MYSFKLLMAILLFFLFIPSTLEAVTTISFNNNNNNNNNNNAVTQQEELSLHDVVSNATTNSTLETLDKRQTANVVVTFNLLVVTTYGQMIGCIGSIAQLGSWNPRMGLAMNTDPAFSTTFPNWIGTISLPAGTAIMYKYVKLADSGETWEADPNRAWTVPSGVASATLYDSWQEDPRSTFITSTITVTSTTSVTNTVRSTTYTTRSVPVTTTITSTAQVGVTNTVTSSTTVTYVYRESGATTADPQPVANTRTATQTSTSITTIVNQQPSTYSTTQIATGTVYQTVYSTVTNTIAGVTTQPATSQTTRIVTATAAPRYTTLQQPMTSTLIPSTETMPILTVYSTSTSVSSFPVTSTSVSTRPITSTTSYLSTTTRVLTSSGNLITQTSIFTGSTTFVTTYSTTYLTTFSQTVTEVSTRSSTIVNTRDVTNTASATLYTTGTASQTNPTSTASAPTRTSTLSDSSTTLPATLVILSSTSILISSIPATSTLITTQPVTRDNPDQHIPFDIFDDFRPNADRIQYAIKQAHEYDLWGFNGCRNGLLERDCEPDVANSDAIGTNENFHFAGIADYVARFYGYLNTSEFVDHVAGRLGHHQFYVHEHITTPTDLGPCVYGCTYFYDKLFEYHHEGNFGIRPSHYPDLHIDPNQHVFNHFKLSVYDAPAWYPDRRKYGTVQRDELERNHFYGRGLNLHHPEYFIAKSYLYSYSSGPDLDESQHSHFALSSRDPFEHKYQGLDWYQHISDDLKLSFYNASARHINICPDRPILYYQLSRHHCHSNSFGIHYIVCYKPCSSIDFYRSPTSNLHPLNINYFANGISGDIQHEHEGLECPGDIHFGLDCTLDFHKQLLNHDHTRYVKQWIFGHSNAHLKRHKYICHNLELTFALHDGANGQLFGYSTIDPNQYHTRNDNSSTLNLPYGDPATHKTHINGYSLASSVFYVPDEPHLTVPGHSAIEHNLADFEHTSYDHRRFHRASDNIDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT72</accession>
    <name>A0A9Q8UT72_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09743</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765932.1">
        <property type="nucleotide sequence ID" value="XM_047908891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT72"/>
    <dbReference type="GeneID" id="71989621"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09743"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF78">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="110"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="63403" checksum="3A7FB44655874E36" modified="2023-09-13" version="1" fragment="single">ASLTSFSPLRRLRGTLRRSLFIGSFWFPSIPRGATSQEYIDGAAYWRGDTRQSTLSTMSSIEKGDIVHDEVLHDHDLNAVDKQTAMHIGVLSEEEKVVEKQLRKKIDTLIMPLVVLVYLMNYIDRNNYAAARLQGLESDLGMSQSEYQLGLSILFVGYVLMQVPSNLMLNYCGKPSWYIGFFIIVWGLVSLLTSQVSSPGGIIACRFILGIVEAPFFPGVLFYLSKWYTKGELNLRMSIFYSGSLISGAFGSLIAAGILSGLQGNLGLSAWQWLYIIEGAITIAIGFVIVFVLPDFPDTWKLLSPEMKHVANRRMALDAAEADVDGGGGMSQWAGCKAAFSDPKTYILAIAYHGITGAAGFQNFYPSLTETLGYPRVITLLLCAPPYIFITFYSLAHGLMSDKIGNRFWFYLYPVPIVIAGALIFMFTDSFGPRYFSLFLLNFIFTMNGTIYAWIANAIPRPPAKRAAALAFMNSVGNAASIWTPFTYDSNDSHYIEAMGINIGLVGIAAIFGVILRFYLQYQNKQLERFENEDSTLTDKDLKKLEKTAQVEGIDIATARALQKGYRYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTB5</accession>
    <name>A0A9Q8UTB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">allantoinase</fullName>
            <ecNumber evidence="6">3.5.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-allantoin + H2O = allantoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17029"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="EC" id="3.5.2.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.5" evidence="6"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765976.1">
        <property type="nucleotide sequence ID" value="XM_047908909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTB5"/>
    <dbReference type="GeneID" id="71989639"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09761"/>
    <dbReference type="OMA" id="SRLHVCH"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000032">
        <property type="entry name" value="Allantoinase Dal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017593">
        <property type="entry name" value="Allantoinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03178">
        <property type="entry name" value="allantoinase"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF2">
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    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="522" mass="56340" checksum="B3CE3FD11B876DA1" modified="2023-09-13" version="1">MAPFATGTDTPHAVDGSPILPGVDASQITVLASSRAVIENRLTAATIVVSRSSGKITSIFDSILPASSFPDGTPYTDYSPYVLMPGLVDAHVHLNEPGRTEWEGFWTGTQAAAFGGVTTVIDMPLNAIPPTTTIQGLKEKVAAARGKCWVDTGFYGGIVPGNVEELKPLVRAGVRGFKGFLIDSGVEEFPAVTSSDIRKVFEELADEPTTVMFHAEMVPPVTASVGDDAQTPLPPLEPTGPLNKYQTFLDSRPSSFEVYAILEVLSLAHLAPRLPLHIVHLSAVEAIPMLRDAREKGVNITAETCFHYLSLAAENIQDGDTRHKCCPPIRSASNQDGLWNEMLLPSDSVIKTVVSDHSPCTPNLKLLPSHVPGAEGGKAAGCNSDQGKGDFFTAWGGISSVGLGLSILWTEAMHRNLDAEETLLNVAKWCCYNTAKQVGLEHRKGSLSVGMDGDICVFDDKGTFEVEPSTMLFRNKCSPYEGKTLRGYARETWLRGRKIHSREQGFKMAKPVGELLLEPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU67</accession>
    <name>A0A9Q8UU67_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">DUF7924 domain-containing protein</fullName>
        </recommendedName>
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    </gene>
    <organism evidence="3 4">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="418"/>
        </location>
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        </location>
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        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22644.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="518" mass="59450" checksum="DE82EB211897296D" modified="2023-09-13" version="1">MCALKLISTEKIDTLVAQSEHRVEARGPQPETQDSLTSKCIDPELRKKRRRTAGAFVFSEAEKRNAECQSGQFQRKSRQDSNCRTQRVSEQDPIEFWARTGQWLKGFSQMSGSEIDGANKRRRSSTPSYSSRARDGSVPPAYTAAYEEELRRYGIMFNDLTTKDSVTTQSKEMCQALLDVHDLTPAYNSCSEETYIRLFQRASKCGEERIRRDLTPHIVPSAELLYVVDRDAALQNVREELSGDWTRCGLLGGTQLRPDYAYGLSSATFSEEERSKLENYTSINNPTKFTDSMYFPFLLCEAKCGKKNINDADRQNVHSASIAVNAIIQLCRVTGEFHAQRLSGQILVFSISHDNERVKIYGHFPLIRDGCITFHRYYVHDYSLDGHGGRDRNTGTNFTRAVYRTFYPQHLRRIQEAVARLPDPRHSSMISEASVGEGETQASEQSSQKRDITSRPPLRRAKSRGSQGELTLMKQQMSKMEQMYKDQINQQQKQMEKQKDDSRRQMEQQKEDSRRQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU72</accession>
    <name>A0A9Q8UU72_PASFU</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71991746"/>
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    </dbReference>
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        <location>
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            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="38353" checksum="3961EE735B8F7AAC" modified="2023-09-13" version="1">MLLDHLTDAADYHTYHTAMSSNFFSQSPTVVLPPQAPNQYFVNNHYGGANGTAPAVNGISPNGLSNSAPFTPTASTPASSLAGRKRSRGDIYTEDGDGEDERLDGSTATPIEEDLVKPRGKPVYGPGMTVLYPEDPGYAMAAASQSGTWVEEGAERRPFQLAHAKRPSVTSRKSQRVDSKAAGPDDLAQLVLPASMREACAEPLIDEATRVLGISWARMDSTEALQINKRAYSKWIQNHYPCLKNVDVWFESSSIPGYLVHGLNAYNGQHEYYIFSHDLTEARLVTNEPSQLLPRLQMLPALHLAAPGGHIRAETDPITAAQNEANDIQADMMAMHGPREPVGICTAHAMELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUQ8</accession>
    <name>A0A9Q8UUQ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multiple RNA-binding domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM MRD1 family.</text>
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        <property type="protein sequence ID" value="UJO23153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767519.1">
        <property type="nucleotide sequence ID" value="XM_047910928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUQ8"/>
    <dbReference type="GeneID" id="71991658"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11780"/>
    <dbReference type="OMA" id="FNNTCIQ"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000247">
        <property type="entry name" value="Multiple RNA-binding domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="304"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="487"/>
            <end position="559"/>
        </location>
    </feature>
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        <location>
            <begin position="598"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="701"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="154"/>
            <end position="296"/>
        </location>
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        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="824" mass="91235" checksum="8636B02B7C2AABC8" modified="2023-09-13" version="1">MDSSTRIFVKGLPPKFSEAELRKHFSQNGRAITDIKYFPDRRFGYVGFKTPEDAQAVVKYFNRTYVRMSRIGVELARPIEERAPPPTARRGTVHATEAPPALAKRKRESEATDKQDDPKLKEFLEAYKSKSKKKEAEDALMQDVGDGAVHEEATVEIPTAESDDEYEQVPKKARHAKVDAPKVDETLSTALPTAEEVSKEINDQNESPAVEGAAPVSDADWARSRTSRLLGLLDDEEEEAVHSRPSGTDDEDEGEETITKSSKPVEEPVSSIPTPPADDNSNQQDEATAAEPVDADVEAVRKSMRLFVRNLPYDARKEDLETEFERFGNLEEVHIALDKKTGTAKGFAFIQYSDPDSAEQAFIDRDGQTFQGRLIHILPGTAKREDKLNDFDVSKLPLKKQNEIKRKREAASSVFNWNALYMNTDAVISSVARRLGLAKSEVLDPTSSDAAVKQAHAETHIIQETKAYFRQQGVDLDSFKKSHRGDTAILVKNIPADCSKDELKRLFEEQGDVKRFLMPPAGTIAIVEFDNAAQCKAAFGTLAYRRVKSSMLFLEKAPKDLFTAKPVSGEEEPQGVSKVNTADLKDADQTVPETTGTVTLFVRNLNFSTTTKVLTEAFTPLAGFLSARVKTREDPKRGTLSMGFGFAEFRTTKEAQAALETMDGYTLEGHKLQVRASHKGADAAEERRKADAAKRSAARSTKIIIKNLPFETTKKDVRALFGAYGQLRSVRVPKKIDRAARGFAFAEFTTSKEAQSAMDALRDTHLLGRRLVLDFAAEETEDAEAAIEKMQQKVGAQVNKVALQKLTSGGRKKFTTSGGDEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="1" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF07065">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="51647" checksum="4298C52836DB5063" modified="2023-09-13" version="1">MDDIEIQRLPLNTAPTARLNAYNRHALAPWIGETGYLTPAYLHRREQERIPFNMARWLSAEISKHMLHEPTRTLRLNKSQITRLLKVAAKSDYSTSKASQYLHELQLIAFSSPPLPKSREGYFIRLSESSPKDVDDGNLQPVHTKTEAFLKTVCSKRAVQALLTLHANDENDAIDNVLYFFPYHTTLDRLSEWRCYIHSNEVVVISQSRFYQAHHPGVEDGSLREMVQQIRALWHEIGPTQGFTECLLDVYAEVHKPDFQVKLIEVNPYGPHCGSESLLFHWVDDAAILLPDAEPTKTILRLVDPESDSTHKLGRKEAYEIGRADIIQDEFNITLNRGLGWILLPHEHRRFMRLKVPGQDFVTRKERLERFRDGYEGSWAERKTQPLYNVPPEDHPRLKKLQKACVEWQDYMTDPEVNYGAGADEVMYHTLYQSLGGFRVAYLRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVK8</accession>
    <name>A0A9Q8UVK8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_13020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992898"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="26970" checksum="1577CD7ABAFB2369" modified="2023-09-13" version="1">MYLRFAIFTFAGLALSLVLEERAPVCVTAGRSCNDTYDELTAFSLQPALSPLVDYCGGRYRGFGIVDTTVLSEPLGLLARLASLIPGLSYVIAQVTLRNLPALGQLASLGLNGLKPQSGDNYIGAATQETLTQFGVVTLNPYATIEPGPEYKTIDLKSAYIGCLTNLDNPLVIVGQGCVISAIAQYANGTKSSPATFTFTPKMLLKNPMQQITFDERVFTGVVKIVFGIASATLPPVLSIFNVDNMVYCAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVN5</accession>
    <name>A0A9Q8UVN5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cruciform cutting endonuclease 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768524.1">
        <property type="nucleotide sequence ID" value="XM_047912874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVN5"/>
    <dbReference type="GeneID" id="71993604"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13726"/>
    <dbReference type="OrthoDB" id="5552842at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000402">
        <property type="term" value="F:crossed form four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070336">
        <property type="term" value="F:flap-structured DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16963">
        <property type="entry name" value="CCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039197">
        <property type="entry name" value="Mrs1/Cce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015242">
        <property type="entry name" value="Ydc2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072:SF1">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09159">
        <property type="entry name" value="Ydc2-catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial resolvase Ydc2 catalytic" evidence="1">
        <location>
            <begin position="53"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="376" mass="42324" checksum="81CD6BE7E9F4BC4A" modified="2023-09-13" version="1">MAILRQPSLKGWQLRYWAYLTGLPTTGTKAELQSSLTATVPQQRQGNTPRRLVSLDMGIRNLAYCVIEPRMPKEKPNQISLVVHSWKRMDLLETAADNFTEDIAVETSQERSIKRVKAKLAAPVTKDSFTPAVLSKTAYRVTKDLLSHEPDTLLIERQRFRSGGAAAIQEWTVRVNMLESMLWASLETLRQEGKMTDAFPTVLAVSPARVAQFWSSAASMSLKPPTLFDEDNGNVQTMITHAMSDRRKIDKKDKVDIVRSWVAGTSDLDLRFEGEAIKIAEAFRLDPRQSKDAVAMAGGKLDDLADCLLQAVTWLIWEENRAVLNKLWQKTVDEIKPSDLSEHNAQTAVHPFSPEWIATRIAFPGMTEKQTADYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVX6</accession>
    <name>A0A9Q8UVX6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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            <begin position="19"/>
            <end position="93"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10236" checksum="9B5B3BCD8D7BD15C" modified="2023-09-13" version="1">MQLHQIFLLLTAAISANACQYYTTSQQDGAATQHACGRVSGASFNDVPHHQCNKGGDGVQNCGWEDECNDYSKTTNNGKTYYQWCWNKVANVG</sequence>
</entry>
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            <authorList>
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                <person name="Chen L.H."/>
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    </dbReference>
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    </dbReference>
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            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="27424" checksum="D8F80C96F8D6B034" modified="2023-09-13" version="1">MSPSNTTILLVPGAWHTADCYTALAKPLEFHGYKTDLINLPSCGHNKRLPNFNEDVAAIRDRITKAANAGQDVVLVGHSYGSIPSNEACKGLLKKDLAAQGKKGGVVHFFFLVSFVIPEGASLIGAFGGNPLPWFVISEDELEVNPATPETIFYNDLEKSEQDHWIGRLKPHSYQVMHTPVTYAAWKDLPCTYLYCMDDQAIPLEIQKMMVEGTAQGCGFRTETVEAGHSPFLSKTKETAEAIVRAAEVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            <dbReference type="PubMed" id="35471194"/>
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        <source>
            <strain evidence="3">Race5_Kim</strain>
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        <location>
            <begin position="21"/>
            <end position="105"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="AQA29259.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="105" mass="12286" checksum="A5EE17885A9C22E1" modified="2017-04-12" version="1">MYFPTILLTLLALFTTSIHGCAHYLNCKCHDSKDNLQNDWVTEQACDKYKTDHGSKQLKYKGAPHHQCVGNPIDDGTRSMDNCEWDKACKSYGTQYYQWCWEKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXY3</accession>
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            <fullName evidence="2">Phytase-like domain-containing protein</fullName>
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
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    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
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    <dbReference type="EMBL" id="KX943146">
        <property type="protein sequence ID" value="AQA29317.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="entry name" value="BLR7070 PROTEIN"/>
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    </dbReference>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4X1</accession>
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        <name evidence="11" type="ORF">CLAFUR5_02254</name>
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901402.1"/>
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    <dbReference type="GeneID" id="71982132"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02254"/>
    <dbReference type="OMA" id="IRHFGVK"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040259399" description="amidophosphoribosyltransferase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="2"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="531"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="531"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO10925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="596" mass="65682" checksum="43030C09F78E422C" modified="2023-09-13" version="1">MCGILAVILASISADAAPELHQALYYLQHRGQDACGIATCSKGAKIFQCKGNGLASKVFNEGKRVKDLPGYMGIGHLRYPTAGSSANSEAQPFYVNSPYGICFTHNGNLINAPALKEYLDQTAHRHINTESDSELMLNIFADELNVTGKARVNAQDIFRALEAMYEKCKGGWACTAMLAGFGLIGFRDPHGIRPMVLGERPSLDVKGGKDYMMASESVALSQNGYTNIRDILPGQAVIIEKGKEPEFRQVSPQLDYAPDIFEYVYFARPESEIDGISVYRSRQLMGYRLAETIKQQLGQEVIKTIDAVIPIPETAMVSAYAVSKHLKIPESQGFVKNRYIFRTFIMPNQTARQRGVRAKLNAIPIEFKDKNVLLVDDSIVRGTTSREIVQMAREAGAKKVYFSSCAPPVTHSHIYGIDLASRNELVAHGRNSRDIAEHIGADDVIYQNLDDLISACAQDSPRDPKTQRFEIGVFCGKYVTPVDQEYFDHLERIRGETKKMKMMEKAVQAVAQGTASQKEIKMAVNGVDVDDHGEVVARDSGSDGEGRLPKKEVRGRISRGNSFVADSAPSRPQNGQERSESQDVALHNINDHGGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5C3</accession>
    <name>A0A9Q8L5C3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755477.1">
        <property type="nucleotide sequence ID" value="XM_047900984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5C3"/>
    <dbReference type="GeneID" id="71981714"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01836"/>
    <dbReference type="OMA" id="NDYRHED"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050463">
        <property type="entry name" value="Gfo/Idh/MocA_oxidrdct_glycsds"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818:SF11">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="17"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="26211" checksum="F05BA12465672BD0" modified="2023-09-13" version="1">MFGMNRTDEATSNSHIIKVGIIGCGMQTQVIHIPLLNSLSNLFQITYLCDVSPAALQHSLLKSPEIPQTPPPPSASPSTSTQVDLVLIATSHVFHARHATLALQAGKYVCIEKPIALTLQDTDAIIAADAAAGGDKVFIGYMRRYAAAFVDVVKEVNSTIVGGEGQIRYARVRDITGSNSVFVSQSGTYPGTFNDYRHEDSEALRIKTASDMHQALEVELGIPLTKQTELIWEVLSTLVFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5I5</accession>
    <name>A0A9Q8L5I5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755651.1">
        <property type="nucleotide sequence ID" value="XM_047899463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5I5"/>
    <dbReference type="GeneID" id="71980193"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00315"/>
    <dbReference type="OMA" id="WILGNLM"/>
    <dbReference type="OrthoDB" id="545683at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.470:FF:000001">
        <property type="entry name" value="GTP-binding protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="436" mass="47133" checksum="1DB5B541DD9FDDEE" modified="2023-09-13" version="1">MPRDPLIGLVGKPSSGKSTTLNSLTDTTAKVGNFPFTTIDPNRAIGYLHIQCACSRTSLPGNQPPSPDEPPPLQTRCKPNYGACQKGTRSVPIELLDVAGLVPGAHQGKGLGNKFLDDLRHADALIHVVDVSGITDAEGKATRGYDPHQDIAWLRSEIVNWILGNLMQKWGGIKRRHTAVKATPVETLSGQFSGYGANPTVVARTLDKTGLKTPLQDWDDETIKFVVETFVDEKFPTVLALNKIDHADADKNVSKIAKAEKPERIVLCSAISEVFLRRLVKQGFVKYIPGSEFLDTREDLIEQGEEDGGGLKEMDEKLKTRIENLKDMVLYRFGSTGVNQVLTRASELLGLTPVWPVRNIGTFGSGGAGSAAGDRAAVFRDCVLVKKGSTVGDVYRKVMGDAPLAYSETVGGVRVAEDDLVSPGKNDILSFKVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5M2</accession>
    <name>A0A9Q8L5M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757137.1">
        <property type="nucleotide sequence ID" value="XM_047900185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8B3"/>
    <dbReference type="GeneID" id="71980915"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01037"/>
    <dbReference type="OMA" id="WRRTDQT"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000171">
        <property type="entry name" value="Glycosyl transferase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="36555" checksum="2BC233EE11053C4B" modified="2023-09-13" version="1">MASHASNGDVNAKPARVVDSPKVWTTLITNTKYLSGLLSLDASLKFVGSKYPLVALYTETFPPEGHKALDVRGIPKKRVNYLLPSTHKDFTNDPRFYDCWSKLTPFSLTEYERVVQLDSDMLVFQNMDELMDIELDGAEQAGKGQKVFAASHACVCNPLKKPHYPKDWTPENCAFTSQHGTPEEAQEKGADPAAGLAMPNGGLQVVVPSDEINELISTKLADPSTMEYDFADQSLLGDLFHGRWVALPYTYNALKTLRWKGVHHQIWQDKRVKNIHYILSPKPWDESEEDKKSNGRDETFQWWHDINDRRLTEEKAKGIEDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8N3</accession>
    <name>A0A9Q8L8N3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00738</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasmic vesicle</location>
            <location evidence="10">COPI-coated vesicle membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757188.1">
        <property type="nucleotide sequence ID" value="XM_047899886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8N3"/>
    <dbReference type="GeneID" id="71980616"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00738"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000260">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="12">
        <location>
            <begin position="21"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="13">
        <location>
            <begin position="680"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="14">
        <location>
            <begin position="820"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO12822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="961" mass="107008" checksum="3FAFCC9AE6B494AF" modified="2023-09-13" version="1">MATFLEQSYSLVHQDNAADQPSLQDLRTQLEKGNDETKQETMKRILTVMLNGDPMPNLLMHIIRFVMPSKSKALKKLLYLYYEICPKLDASGKLKQEMILVCNGIRMDLQHPNEYIRGNTLRFLCKLREPELIEPLLAPARQCLEHRHSYVRKNAVFAIASIFQHSEALMPDAPELIQTFLESESDNTCKRNAFAALLSISHEKALEYLSGVFEGIPNASELLQLVELEFIRKDAVQNQGNKARYLRLIFDLLEAKDSTVVYEAASSLTALTNNPVAVKAAAGKFIELAIKESDNNVKLIVLEKVNTLRKSNEGILDDLTMEILRVLSSPDLDVRKKALELAMDMVSSKNVEEVVMLLKKELAKTVDEQYEKNNEYRSLLIHSIHQCAIKFSEIAQSVVGLLMDFISDFNNASAVDVISFVKEVVERFPKMRSSIVERLVTTLSEVRAGKVYRGSLWIIGEYSLEQNDIKEAWKRIRASLGEIPIVASEARLLEEQPDGEPELNEQVNGHAKPAAPTGSRKVLADGTYATESALTSQASAKAKLDAVKAAQKPPLRQLILDGDYFLATVLSSTLTKLVMRFSEISSDAARTNALRAEAMLIMISIIRAGQSQFVKAPIDEDSVDRLMSCVRSLAEFAQKKDLETAFLDDTRKAFRDMVQVEEKKRAEKDAVLKAQSAIQVDDVVSIRQLSKKTTDGADEAEVDLEKATGGDATTEDLTSKLSRVVQLTGFSDPVYAEAYVQVHQFDIILDVLLVNQTRDTLQNLSVEFATLGDLKVVERPTTQNLPGLDFLNVQATIKVSSTDTGVIFGNVVYDGPSATDSNVVILNDVHVDIMDYIQPAQCTETQFRTMWTEFEWENKVNINTKMPEGKGLRDFLQRLMKVTNMSCLTPEASLEGECQFLSANLYARSVFGEDALANLSVEKEGEHGPVTGFMRIRSRSQGLALSLGSLKGLSKIGELAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8X0</accession>
    <name>A0A9Q8L8X0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_01150</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase d subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757307.1">
        <property type="nucleotide sequence ID" value="XM_047900298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8X0"/>
    <dbReference type="GeneID" id="71981028"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01150"/>
    <dbReference type="OMA" id="VSKGRWA"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO12941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="19615" checksum="1986B242F28ECC13" modified="2023-09-13" version="1">MAATRSASTKIDWANLGSKLGLRGSTAQSLAAFKQRNDIARRKVQVLSDQPQTVDFAQYRSLLKNQDIVNDLEKQFTSFQPKKYDVQRQVKAIEAFEAQAIKSAEETKGKVDAELEDLEKTLKNIESARPFEDLTVDEVVAARPDIDKRVEQLVSKGRWQVPGYQEKFGNLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L975</accession>
    <name>A0A9Q8L975_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757616.1">
        <property type="nucleotide sequence ID" value="XM_047901663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L975"/>
    <dbReference type="GeneID" id="71982393"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02515"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="37018" checksum="23BBBB7AB1E285AA" modified="2023-09-13" version="1">MEYQLPPSRNPSRNAVLPSESGPAMAAATTRPFEESLLREWASIIREKKALLELSPNGLLQLMPLLGDDAIPIIADEIKYLSGQSHHYVRPTRYRGTRSSRFDYCTLSKDVLRLGNIPGAIAEAARLVCSLFESHLCKTETTLFNPNYDKISYVCWIFDNLLADTIRIMKISSKQWYDGWNPQQVLNTVQRLRTHNTRRVSRIVMSERVKQRKPCGVGISLENSPIFTRSIQSLQRPFIRHSREVGIILATKTAGHHLPPELVEMISDYFWDKDLLKALEADLARRIREAASASAVATQGTKQLVAASKDNVQAGEKLPIDLTKGYMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9G3</accession>
    <name>A0A9Q8L9G3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Translocation protein sec63</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02871</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902019.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71982749"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02871"/>
    <dbReference type="OMA" id="RAILHAH"/>
    <dbReference type="OrthoDB" id="1734229at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein translocation complex component (Npl1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
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    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
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    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="107"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="621"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="671"/>
            <end position="698"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAL7</accession>
    <name>A0A9Q8LAL7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02771</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758206.1">
        <property type="nucleotide sequence ID" value="XM_047901919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAL7"/>
    <dbReference type="GeneID" id="71982649"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02771"/>
    <dbReference type="OMA" id="LPAKNFG"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14819" checksum="BB086B32DDA03ABA" modified="2023-09-13" version="1">MVKTSVLNDALNAINNAEKTGKRQVLIRPSSKVIVKFLQVMQRHGYIGEFEEVDDHRNGKIVIQLNGRLNKTGVISPRYNVQLNDLEKWVVKLLPSRQFGYIVLTTSAGIMDHEEARRKHVAGKIIGFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBH1</accession>
    <name>A0A9Q8LBH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor cwf23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758724.1">
        <property type="nucleotide sequence ID" value="XM_047901511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBH1"/>
    <dbReference type="GeneID" id="71982241"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02363"/>
    <dbReference type="OMA" id="HFLQIAY"/>
    <dbReference type="OrthoDB" id="376357at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43744" checksum="D544BE97022E105B" modified="2023-09-13" version="1">MASDGDLKDHALNSSHDFYRLLGIAVSANSAEIRTAYRKTALKYHPDKVASNQEALDKFHLLQVAYDVLSDENVRALYDNARRAREEKKLRESAYSDKRRQMKDELEARERAGVAGLKRKREDAREEEAFQQELKRLAADGARRRKEREEMLRKEMADAMEEERKERTPEPQPTAPTKVEETDRTIKLRYPAGTTDLGQSQLTSLFERFGKIEHVLLRDKKIKPEGEKHRKDYTIAIIVYESIVAAHKAVTDFPHLMKQEPAIWGRFEDVNWQSGKEPDCIPKPKRKEESASSTPHSTPKTKGYATGDAPSTPAARFKTEHGLKKVPSFGSFKGTPKAATGTPTSGLDAEDAMMIRLKQAAERKRLAEEIKRQEAEEEAALEQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC17</accession>
    <name>A0A9Q8LC17_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Efflux pump dotC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Dothistromin biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_08148</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Efflux pump; part of the gene cluster that mediates the biosynthesis of dothistromin (DOTH), a polyketide toxin very similar in structure to the aflatoxin precursor, versicolorin B. One function of dotC may be to transport early-stage dothistromin biosynthetic intermediates from the cytoplasm into vacuoles, thereby affecting the rate of dothistromin production.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759043.1">
        <property type="nucleotide sequence ID" value="XM_047907296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC17"/>
    <dbReference type="GeneID" id="71988026"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08148"/>
    <dbReference type="OMA" id="LQPMWIM"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000014">
        <property type="entry name" value="MFS drug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="101"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="592"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="658"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="686"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00057269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO14677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="699" mass="75464" checksum="4EDF10754F5FA584" modified="2023-09-13" version="1">MSSTEDHKSRSDTSRLPEESSRTDSKTVSPASVRDSSETLHSIGHVTVEDPRCDALQRLESHPYHQGLQFEESEKPTATAQDEDNKDGKIMGRTKGKIAVIMLALCLAVFLAALDVTIITTALPTISEHFHSSAGYTWIGSAFLLANAASIPSWGKVSDIFGRKPMLLLANIIFMIGSLVAALSNSIGMLIAARAVQGLGGGGLIILVNIVIGDLFPLRIRGAFYGVIGGVWAIASSVGPIIGGAFTQAVSWRWCFWINLPLDGIAFIILLVFLDIKTPRTPLVEGLKAVDWIGTLTVVGGTLMFLFGLQYGGVTAPWDSALVLCLLIFGGLTLAIFLVWEWKAAKFPIIPMAIFSSVTNCATLAIVFLHGFVFISASYYLPLYFQAIRGATPILSGVYLLPTALALAVGSIATGVTIAKTGKFLPPIYFGFFMMAVGFGLFINFDAYSSWAKLILFQVVAGLGVGLIFQAPIIALQAHIQPRDIGTATATLGFIRQLATTISVVIGEVVYQNQLKKKIPGLATVLSPQELGRISGGNAGANTEFIDQLPQPQKGAVRVAFADSLQPMWIMYTCFAAVGFVTMFLIKRKQLTRQHEETKTGIEAEKANRESRLQEAAEKRASKASLSADKRASKLSFKRRSQGRPISGDTEDPKSRPTSEVPTEATPHSSWEKDLEPGPRPPVPRIPEEHSSKENVSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCT2</accession>
    <name>A0A9Q8LCT2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759376.1">
        <property type="nucleotide sequence ID" value="XM_047907282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCT2"/>
    <dbReference type="GeneID" id="71988012"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08134"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="507" mass="57639" checksum="E322855A3A6EB6DA" modified="2023-09-13" version="1">MSNTNFLGHTAERLCQQAQELMREAQTLQDRAWIYTQEADALVQARAQPSHFTPEKFSWASDEDEPAADEPSSSQARGSARKGSRRLQLSKSKTGSAKARTGRRGSAQKGIEGIPQEVFDMILDELLDDYRRWYYSEDPGLLALRSTSRKLNQMTTLRFAEKSFTNTTFIISVEDDRQIALALASHPVFGPAMKEVTLNFDELADPEKAYDYFTKPAAFPANYKLTQHDWRRATVIDSGRQLQTLVELLSTLKSTGKFEQLTLQTVGQDVWASGQGGERLYKQLYGSLPETKNHMNTWSKLFKRPQREDSMRHFKTTLEALIVAELDVPTFDVSSSAFDYTITIDMLARNPGMLQMLGLPTVDLAPVVDLIVGTPRLRSLHLVGSPEAPATTVFVDTVLSSRLPALRELFLWDTFVFRDRLETFVKRHRQLDLLATVKCRLYTESLLVVRSSPEMLLAESLDYVKSRKADDVGRLKRDKDRLRWDYDRLLEDFTVDGISPAHLPDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCU5</accession>
    <name>A0A9Q8LCU5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758744.1">
        <property type="nucleotide sequence ID" value="XM_047902862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCU5"/>
    <dbReference type="GeneID" id="71983592"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03714"/>
    <dbReference type="OMA" id="VICEPQH"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="232" mass="25270" checksum="345EC95F1A96B6D7" modified="2023-09-13" version="1">MSICVAELKEVHSGMRDRYVTPHTNHRSWDLHHWISGLTSPALDTTNLRTVSGTQQQPSIPPHDCRMVRSTAEGLASLGNSSTIVLFTPVIAPAGSAKATNKTNGSADPFEPLGRALSRHHKRVRHVPYVPNIGFTETHDAFLSQADAVIVVICEPDAGKHEALANQVDFAEATRDGLEESSCAGSLILIQCGDARGTFWPDLSQFDNTLKCQSYDSNTAQQIARKLVESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD18</accession>
    <name>A0A9Q8LD18_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759534.1">
        <property type="nucleotide sequence ID" value="XM_047907783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD18"/>
    <dbReference type="GeneID" id="71988513"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08635"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="51"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="471" mass="50354" checksum="55A1D5A514DC43F3" modified="2023-09-13" version="1">MQNDVKAETGWHTENAQEKRRYSYGYDPEADTCVTNDAVFGDVTNGPNYRNVGWMGGVVLMLKTQIGLGVLGIPLVFDTVGMVPGVICLLAIAIMTTWSDYIVGIFKINHPEVYGIDDVGGLLMGKAGYIIMGTVFCLFWIFVAGSAMVSISIALNALSLHGACTAVFVAVAAIIGFLFSSIQTLGRITWLAWVGVVGIISAILVLTVAVGVQDRPSAAPQTGPWSSDYRITATPTPASAFQALSTLVFAYAGTPAFFSIVSEMREPRKYVRSMAICQGVVTALYLAIGIVVYYFCGSYVASPALGSAGVLMKRICYGLALPGLLASMILLSHVPAKFIFVRILKGSHHLSSNTPTHWIVWLCCTAGIALVSYILASAIPVFGELVSFAGAAFGTLLCLQPMGFMWLYDNWSRPNRDFKWKLGVAWAWFIIIGGTFLTIAGTYGSIVGIINALDAGASTSPWSCADNSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDA0</accession>
    <name>A0A9Q8LDA0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arsenite methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07818</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O = dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:69464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:23808"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:69432"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27130"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>arsenic triglutathione + [thioredoxin]-dithiol + S-adenosyl-L-methionine + 2 H2O = methylarsonous acid + [thioredoxin]-disulfide + 3 glutathione + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17826"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:183640"/>
            <dbReference type="EC" id="2.1.1.137"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.137" evidence="4"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759480.1">
        <property type="nucleotide sequence ID" value="XM_047906966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDA0"/>
    <dbReference type="GeneID" id="71987696"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07818"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030791">
        <property type="term" value="F:arsenite methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="ARSENITE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675:SF8">
        <property type="entry name" value="ARSENITE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="9">
        <location>
            <begin position="65"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="292" mass="31062" checksum="97387EEDF8F97A21" modified="2023-09-13" version="1">MGSTTIYDQVTTHYGKAAKEDYGDGSYGARVAAEFGYSQEELDSVPQESNLGLSCGNPLAIAGIREGEVVVDLGSGAGFDVFQVAKKVGLKGKAIGIDSSDDMLARANQIKTKLSHGDNVQFVKSGITDISLEDSSADCIISNCVVNLVPEEDKHLVFTEMARVLKPGGRVAISDILAKGPLPEEVKNSMALYVGCIAGASQVESYEKWLREAAFKDVLIVYSKSDLNVYRHSDGTNAGCCAPPEPAKEEKKGGCCGPKKTSVPAQAKTVEDFGDVDFNQFAGSFKIYAIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEK2</accession>
    <name>A0A9Q8LEK2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Decarboxylase tropJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759614.1">
        <property type="nucleotide sequence ID" value="XM_047907224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEK2"/>
    <dbReference type="GeneID" id="71987954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08076"/>
    <dbReference type="OrthoDB" id="2932980at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050197">
        <property type="entry name" value="Aldolase_class_II_sugar_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789:SF0">
        <property type="entry name" value="3-OXO-TETRONATE 4-PHOSPHATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789">
        <property type="entry name" value="FUCULOSE PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="3">
        <location>
            <begin position="47"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="34528" checksum="D1EBBDDE70367500" modified="2023-09-13" version="1">MLLRVYLVQQCGRCRVGRRIIFLQHLRSVVDDSYTTMQLSNLTETLRMLVTANHILHQHNAVDGFGHISVRHPQNASLYIMSGYLAPALVSTADDLIEYNVEGSMPVDPNAGKGYSERFIHGEMYKRWTGVNCVVHSHAEAVLPYVASDVPLLPMYHMAGFQGSEALPVWDITPLYEEEPEHQQDMLVNEARFGEGLADSFAGPFSNDSDSTSPAHTVVLMKRHGCATWGPDIPTAVDRTLYTLTNAGVQTNAMAVQAAARAAGLVQNATIEGLGKRQADDCRKMNEGTQDKAWQLWEREVEVNALYQNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFW2</accession>
    <name>A0A9Q8LFW2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761020.1">
        <property type="nucleotide sequence ID" value="XM_047903199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFW2"/>
    <dbReference type="GeneID" id="71983929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04051"/>
    <dbReference type="OrthoDB" id="3650939at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="106"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="24495" checksum="BFAFCE747C31C612" modified="2023-09-13" version="1">MSCSQHTHCFTHYWQSDRRFQTWDNHELQSYLHTAGYHFEHNASHARLQSLCARAARGLMSYEGLTAPQLQRLCTRRKVSVPVKLTGRKLALRALLVAADERPRQFTKFTQLPTEIRVMIYSHHTKWLQTRLGSCDSQPARVADWSFVAPPPPPLARVSRQLRDEFLPEFYTAVNFRSIALPANPPHDLPPSGRAVLVGMYRRHHPIPRLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG10</accession>
    <name>A0A9Q8LG10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761073.1">
        <property type="nucleotide sequence ID" value="XM_047904282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG10"/>
    <dbReference type="GeneID" id="71985012"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05134"/>
    <dbReference type="OMA" id="CILAFQW"/>
    <dbReference type="OrthoDB" id="3628122at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16172" checksum="F3127EBB5AC621CC" modified="2023-09-13" version="1">MQSTLNQAAIVEEIEGLTHQLVEAINDRDWTASRWSFVAPTFMIKPRSMTRPTEGGSTHVTLDEWLDTWKMFAKKNPNFSLQVADISAVVNDKMGTAETLFNIAVSGVYPGIVTKVVCVLACQYMRPGKWVPVRHEGLSGADVIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGH7</accession>
    <name>A0A9Q8LGH7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_04312</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase M36 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761426.1">
        <property type="nucleotide sequence ID" value="XM_047903460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGH7"/>
    <dbReference type="GeneID" id="71984190"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04312"/>
    <dbReference type="OrthoDB" id="3227768at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040534249" description="Extracellular metalloproteinase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="14">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO17060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="641" mass="70612" checksum="E56EE20DE1D50F13" modified="2023-09-13" version="1">MRSSQIAALSSLVLGTLSHPFHDSHALESDPEALQRRQLSSRLDDFRPQQRSRYVAEDGEISVQRTSAPASTDPIEAATNHLRSIHPDAEFRTANDNHVSSNGIAHVYFKQTLNGLDIDDADFNVNVRPDGTIFSYGSSFYTGPLPEAAPAPEEVAEPQPVLETVVDVLALPIQPAEADILVEETARSFTVQGLNNVESPPEGQLVYYGNAEGNLISAWRLETDVSENWLTTYVDATNENNILAVTDYVAESTYEVFKWPLNDPRGNRRTTEILPFDIRASSLGWHRDSDTRYTVTRGNNAIAQPNTDGDAEFLDEPRPSGGLLNVYTPRFDPALEPAQYIDASTVQLFYTSNYYRDMLYILGFTEAAGNFQTSNFGKGGVGGDSVILNTQDGSGLNNANFATPPDGQQGRMRMYVFNQSVPNRDSSFEAGIVIHEFTHGLTNRLTGGPANSRCLQVLESGGMGEGWSDFYATAIRSTPRDNRNTNYPIGDYAFNNPAGIRAFVYSTNMQTNPYTYSSLNTLTRVHQFGTVWCTMLYEMMWNLIDDHGNTALLRPVLGFNGRPDDGKYLSMKLVLDALTLQPCNPTFVQARNAILDADRALTKGGNQCSIWKAFAKRGLGENASQVGTVYTDDFTIPAGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGI6</accession>
    <name>A0A9Q8LGI6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761441.1">
        <property type="nucleotide sequence ID" value="XM_047903822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGI6"/>
    <dbReference type="GeneID" id="71984552"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04674"/>
    <dbReference type="OMA" id="WPDENDK"/>
    <dbReference type="OrthoDB" id="275783at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051500">
        <property type="term" value="F:D-tyrosyl-tRNA(Tyr) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.80.10:FF:000001">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="175"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="23414" checksum="3F7CB85D1E18336A" modified="2023-09-13" version="1">MKAVIQRVKSASVTVDGQLVSTIGKGLLVFAAIGKDDTAKEAESMASKVLKVKFWDGDDGKKWKQNVQDIDGDVLCVSQFTLLASTKKGNKPDFHKAAPPALGKELYDTFFNQVRKLYREDRVKDGVFQAMMDVGLVNDGPVGDSDPQGDDPAAFPLPPIALDYRSEDEVVTIEMETNPPEMRNPTNMEPLKEGHTTKTNVQKTFELPASLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGJ9</accession>
    <name>A0A9Q8LGJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Apoptosis-inducing factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04691</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761387.1">
        <property type="nucleotide sequence ID" value="XM_047903839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGJ9"/>
    <dbReference type="GeneID" id="71984569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04691"/>
    <dbReference type="OrthoDB" id="6029at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03478">
        <property type="entry name" value="Rieske_AIFL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050446">
        <property type="entry name" value="FAD-oxidoreductase/Apoptosis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557:SF2">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="49"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="595" mass="64405" checksum="37491B4747CB4F9C" modified="2023-09-13" version="1">MQSTRTFVSSLLRRPYTQPLTAAKQSFTARPTRPFSATTRAMATEYKLKGITSLDGLKNGQTQEVEVEGVEEGKVLLAKVKDEVHALSPKCTHYGAPLSKGVLTPDGRLTCPWHGACFDVKTGDIEDAPAPNPLQKFKIVQKDGEVYIKGSREQILANKRTLNIKCQAKGNDHVVIIGRGSGAFGAIDGLRAGGYTGHITSIAEEDYPPIDRTKLSKALITDVSSIQWRTPETYKEADVTFVQGLAESVDFSGQKVKTKNGKEFSYTKLILASGGTPRHLPLDGLKDDLKNVFLLRTPQHTQEIMKAAGEDGAKKVVVIGSSFIGMEVGNALAGKKHNVSIIGMESEPMERVMGTQVGSIFRKILEQNGVKFYMGASVEKGEPSSRDPSSIGSVVLKDGTKLEADFVIEGVGVRPSTDYLQNNSSINLEKDGSVSVDDSFAVKGLKDVWAIGDIATYPYNGPGGNGKPVRIEHWNVAQNMGRSVALSINSPGSKPKAFIPVFWSALGAQLRYCGHTPNGFDDVTIHGNTDVSEGKQSFVAYYNKGEDIVAVASMMRDPYMTQSAELMRRGKMPTKSEIAKGVDIMEISVPAEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGU3</accession>
    <name>A0A9Q8LGU3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761522.1">
        <property type="nucleotide sequence ID" value="XM_047903586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGU3"/>
    <dbReference type="GeneID" id="71984316"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04438"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="27682" checksum="EA6F837EC5C2A281" modified="2023-09-13" version="1">MASLTRAIDIGPPTAQLDSLFYTLPPELRTIIFEFVVPRLEGDLNGAEEREDLSESDESTTFLTLALAKRSRRFRRRLAFLLSCRAFYLEACGLYYKHREIGLEDVYWGEAAESRHTHSRHRLASIQKVAVIIQDATRIMKLMAHHPKLKSLRFLMAGDDDRGMQTRSWRGQRQRSAVLWNRRLRIELKGLKQAMRKIPSLTGVEFVTEELFNYNVADVAQLREMEAGLNKYLKEREGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGY1</accession>
    <name>A0A9Q8LGY1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-linked oxidoreductase ZEB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761582.1">
        <property type="nucleotide sequence ID" value="XM_047905275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGY1"/>
    <dbReference type="GeneID" id="71986005"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06127"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="33543" checksum="464CE66994D91B83" modified="2023-09-13" version="1">MKIPTVEGRLIRAVPPAAVCFQNNTTYNSTACQEVLSQFTSSAFHAADPVSLDTPDAYLGCLPLHANGTSFLGEPFAGRRGCHADDHYPAYVINVTTTSHVQAGVKFRLNVKNTGHGRSAQPDSLSIWTHCLKSMEFSRNWQPEGRPDNDTASRAAMTFGAGVQDREAFEAAAEHDHVVGGGTDSTVGLVGWLSGGQGANNVLEAEIVTPAGDIVVANEYQNTDLFWAIRGELISLSVQAYPVPRTSLWSLAVSANNGTTDADWYKIVARALPAGGGPGASSSRLLPASSLTKDLDGLEADDGQSQKSTGRPVTDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGZ6</accession>
    <name>A0A9Q8LGZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Set1 complex component swd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760829.1">
        <property type="nucleotide sequence ID" value="XM_047903510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGZ6"/>
    <dbReference type="GeneID" id="71984240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04362"/>
    <dbReference type="OMA" id="DYEDDIM"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="7">
        <location>
            <begin position="33"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="53586" checksum="38CF524C98876D99" modified="2023-09-13" version="1">MNLPLSDPVLLAQDIPETLTARLRSSGQAVCIRFSHRGDLLASGTAKGTIAIFDLETNGVARKLKGHTAGRTVQSLSWERSGRYLLSSSVDWKVILWDLKDGSRVRTVNLGAPVYIAELHPANAMMCVAALYEYRPVLADFTHDEKIKQMALPNLPKRAPHEIEGNEKADAKHFTTVAAFAPTGSHIITGTTKGWLNVIDAHTRETVYSNRLCSKPILLIRLSSSGRDLLVNASDTIIRTIKLPDLSDPKLQPDSIRLEVEHKFQDVVNRLSWNHVAFSSNADYVMASTLMNHDIYIWERGHGSLVKILEGPKEELGAVEWHPTRPFVAATGVESGKIYLWSINTPQRWSALAPDFVEVEENHEYIEKEDEFDIHNTAELQKRRLDQEDEDVDVLTVDEEQLEREGKINKGAHEEFRMPVLLDMDDSDSEDEMIAIGAGQFRRKSTAQADDLDFVDGNDAAHGEVETNGHAGMKRRRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH23</accession>
    <name>A0A9Q8LH23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761611.1">
        <property type="nucleotide sequence ID" value="XM_047904710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH23"/>
    <dbReference type="GeneID" id="71985440"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05562"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="108" mass="12632" checksum="5F19E1CDB5C51638" modified="2023-09-13" version="1">MQVPTWSSVCELELSRFNDRDRDLLTPLKQQTPRLTRLSFHELTHTNDERWDNILSVMEARLRLENVKLSGSRCDDVPERMNQLIFSVMSPSREEDDDTGQERPDGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHR7</accession>
    <name>A0A9Q8LHR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Muconate cycloisomerase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762237.1">
        <property type="nucleotide sequence ID" value="XM_047905413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHR7"/>
    <dbReference type="GeneID" id="71986143"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06265"/>
    <dbReference type="OrthoDB" id="1715191at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="650" mass="70312" checksum="A6F516A3AE8E5B7B" modified="2023-09-13" version="1">MDFIVGSFNHSSLYLLQFTPASGSNESSLKVIREHPAIAGHSWLSLSQDKKFLYCTAWLEKPAIAAYRVGANGRDIQFLNAKNVKALSGYVCSNQSHVFSAGGPSGEVFRREADGTIGDLVQELDYVSGQGENQSEKRGDVAHGSFGGLRHGAHSVDLSPDGESLYVADIGRNCIWTYKVIHSKRGISDPPLELSSKHISPREHDGPRHTWPHPNGKVLYSLQEHSSMVDVFAIAEDGVTLEHKQGCSVLPSGKDCKKYWADEVRHSTGPDPAKPRYLYASNRGLDAGTMGHVAAYKLKDDGFLKSEDPIDIFETPTSGGLANAVEPAPWTKHTGDEEYLALTDSQDGWVSILSFDGKKIKEVSKVNLGKTNDGKVVTFAWQAITILSGTQGIQRVSENRTIEYYPNNIVIGTVRDISATQARLSKDGITSSNIHLLPVEITNAASVQKAAQDVAAITGGSLDFLIQNAALVDTSTAYKSVLDLDPQELGERLKASFDPNVVGTAYVLSYFIPLIRQSQGKKVLVTSTGMADLDIINKFDLEFAVPYSVSKAAMNLLVGKYHAAVGRSDGILVFSVSPGFVDTSEGKQPTEEELKGMQAMGAKFATYTPDFSGPITVGESVGDMAKLLKRATVDEFGGGFVSQKGDKKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHT0</accession>
    <name>A0A9Q8LHT0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase FUB4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762058.1">
        <property type="nucleotide sequence ID" value="XM_047904614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHT0"/>
    <dbReference type="GeneID" id="71985344"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05466"/>
    <dbReference type="OMA" id="LHGHGTS"/>
    <dbReference type="OrthoDB" id="3631038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF7">
        <property type="entry name" value="SERINE HYDROLASE FSH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="213"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="280" mass="31224" checksum="F8D0CC70BD2288D9" modified="2023-09-13" version="1">MRFLCLHGSGTSGHILGYQLSALKSSLPGSHTFDFLDGPCPSTAGPGVKPFFDPPYYSWWQSLSKETVILAIKHLLQHITNSGKVYDVVIGFSQGTALLAATTLYCQNEGIPIPWKAAICICGGMPYSFLEEYMLISEKAKALVVQTRKDLDTASDRNAKKIEAMMQNGTRVDLWDSPSTLWDGKEAITRDPWTLPPVDEKDVYGLDLSNLPEQARLNIPMAHVYGHKDPMSAFHVQLAMLSDPARRIVYDHRGGHEVPRVPHVVRDLVRVVERVERQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHU6</accession>
    <name>A0A9Q8LHU6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762131.1">
        <property type="nucleotide sequence ID" value="XM_047905484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHU6"/>
    <dbReference type="GeneID" id="71986214"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06336"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="752" mass="80525" checksum="69B7971A896E286B" modified="2023-09-13" version="1">MSAHTMDSSKASFGGDALQLTTMPEVIAALEQEYDCKAEEIIPPAQRPYERQPGKKRKRLTLSNFERNPSNRQWAQLKPTDWELELGLAILTFLRDTKHLSLKHIHRSQAVATAIFLRHKTQNTTNRDVNGALPSDIRRARKNVEAERGGLDVAISIYCGDAEAVIYDYNEVRVGQKWREVTPISPVNEQTVSDNSTSDSEADTGTAGVEAVSGGELGSATSLNTPGTSNYTDESPQEQSVKVDSPAGDEATTEDARSQDKGDDKVAANQEAVDGAGGEEEDDDDDDDFIIITERPEPKLTPLEAEMERLGQKFGALNMAEPSFADSYADLDAIKNGPTRKAHGSDITIPPELSLVPTSAEGPSLPEADVNTSTANQPGEAETLQPEDRAPSFVGSPEIQVDQEIVQDGESASPFLRAPSSSGNVDSGNKSEQHLEQPITTDGPPDDPSSATYPPMPNNSSTTHAAQSTFRAQNSPSTRPNIPISTVNAAPHLPEVVAKDPASKGANSASDPVNVGSGHALPTPVAVEQPKEVEMVQTEPASPSPHTTGKHDFSPSVKIYVQHGRISKADQRPIVGTLSSAAVEPRSSSFAEVSTDMEVDEEAVNATQQLPDDMETDDDTFGASVLVTAHSMAPLPATVDVDTDMDDVQASQPAHGPEKMISPGHRSTGKHPTPQSTGAAPTAQTPNVSSASQVDVSMADTSDLGQEGDGANIRRGSAILLKFTDFLTRWELQHDPRHKETQSRSKQDHIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI19</accession>
    <name>A0A9Q8LI19_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anucleate primary sterigmata protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762387.1">
        <property type="nucleotide sequence ID" value="XM_047905330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71986060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06182"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1427"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="801"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1254"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1548"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1724"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="343"/>
        </location>
    </feature>
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        <location>
            <begin position="401"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="885"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="644"/>
            <end position="657"/>
        </location>
    </feature>
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        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
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        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
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        <location>
            <begin position="1290"/>
            <end position="1304"/>
        </location>
    </feature>
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        <location>
            <begin position="1348"/>
            <end position="1360"/>
        </location>
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        <location>
            <begin position="1361"/>
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        </location>
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        <location>
            <begin position="1567"/>
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        </location>
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        <location>
            <begin position="1590"/>
            <end position="1602"/>
        </location>
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        <location>
            <begin position="1611"/>
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        <location>
            <begin position="1660"/>
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        <location>
            <begin position="1733"/>
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        </location>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1746" mass="193214" checksum="50A8091791C2EDEB" modified="2023-09-13" version="1">MAAANMPPGAVPSNGMVDPFTSSPSSHANPAPLRYAAFDNEQLSLAATNSPSSARRALEAHLKNTDRRIHEASRLGTTLIQQRKDLAAKLKEVEEMQTESQVPDELRQKLSELEREYNEVGRESARAFLPKSRVVSEATDSTAGSGIISGSGRDSPTKAQAPSMSRRQRNQPANRVHDIEFATEISTSLIAQVRQLQAALAEKDDELKDTTAAKALLEAEAAHLVQRLRHMDENEQKYKDENWNLETKLQDMEATLKESMDKESRLVQILRSTQTEKASKERELDDLKVTHEKLSEDHAMVKKVQEADLHGLKRDAAVHETEKGRLERRIAELVAQNTELAKAVSYRMGHPVQQSDTDFVSAEEGIQSDSQSPFDSAPPSPIKGTPARHGMLEQETLKSSLNHAHRMIQNLKNTIHREKTEKIELKRMLQDARDEIETRRESTGIVGANMAKKRRSEPEGIKFKRPSTNRLGATRTSTTEILEDEPDWEDHEIEQTPSKPRSAGVAAGTSATGAAGMAAYDHAYGRSEDDSTDAFDTAHERDTTTESEAFATGKEDFGDDTTDGDLTETEGNGNHTLRSVGSFTSRPKAEHRQSYMSTASMSGDDDDDQIVRTPVHNAQQPKYKLRLSRGVRRSGRVSDMIADSPNAASNNSPTSSNGTPQRAQQTLGDELDALDEDSMEGTPSSSFVMDDEGTPNTQRELSVDPGTPSKAEAETAAVVAEREMSQEPGIVSSAIIPRKPDMIDSGMMTEPWEPERIIEERIAEKEIRVEVPVHDQSLQDHAGDLIGGALAGIGVSRFVGGQHDGSREVDGSSQASGDSSNHDLARVQTAETEIARPASQSRSPGGSEGLPSDKDHTRLQFSTITDPRDDEIETYKAQIAHVTKLHEDQTERQRLEAQQAQAAREAEIERVKSEMKQVQESRDSEVQKVKSELQQLQGARVAEVEKASAEIKQLKDTRTAEIEMYKQELMQVNQSREQEQQGHSAEIEALKRHGAESSQAIAQLKLDHNRQLQHFKGLVSEISEKLTVAEQEREELQHDHAVVTSQLHDLSKQHAHLRSQHAQMESEREQLKQEHYNSNTQFEHLKRQFMEMQSRHAQAEETIRVLTPDPASLAFSDLIAQDVKPVEIDFPEHDTPFVPRRSSKRPENVPGSSTEQQEPKTLLTHNYHDHPLVATDEEDENEPNESPVDTADFPRPPLAEISTNAPPSRPPPGPPMTDEGSQTLVSGKDIDSILRNKTAIVPGKDAAISGAATAAALSSLPPVPTSPSRDRSTEARPSIYESPTLKQPRRPSSSGSMRARAAGAPPLPADHTRKIAEAQRAPGTPTGQPAFGTMGPPAMPASAYKRPSTRDRTMNERVGSRDSTTPRPVQTRTSRSQMASDRVSHRTSVSSFASELDERFNISRGHGVYPDDITPPTDPRMIQAITQTMIGEYLWKYTRKAGRSETSNTRHRRFFWVHPYTRTLYWSEQDPSTAGKNMLKAKSVAIDSVRVITDDNAYPPGLHRKSLVVVTPGREIVFTAPTAQRHETWFNALSYLLLRTDKEKGEAQDTFDESDLDEFRPGLGRSVSRSISKMTGQQRSSSRQSRDRASLSSYNSRTTRNTSPRRHDANRTLTNRHGTVTQQAKTLQPPTFNNGLTSTVSNNSRQSSGSVGGRFTSLTSRFRPSSSGRSGSALSHRRDNFDPASIYDASVAADSAEDLRAVIEQQDKQADRLEDVRACCDGRHNVGSLSRANGRHSHGHHSHSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI21</accession>
    <name>A0A9Q8LI21_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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            <end position="92"/>
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            <begin position="107"/>
            <end position="130"/>
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    </feature>
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        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14403" checksum="679F567927C5A2B9" modified="2023-09-13" version="1">MLESMRKEAPLWKNSTLATLSRGRYVAEIFEDTEKLLEMRDAADGHDVYLFPDETRVRHAAESPSEPHQDRSSLATTLGSGSVESYPMLPMSPSFAPLKIIDNDDAYREPSATDGAEGALLRVARAPSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK3</accession>
    <name>A0A9Q8LIK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK3"/>
    <dbReference type="GeneID" id="71986207"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06329"/>
    <dbReference type="OMA" id="PIRTYRI"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38918" checksum="0419FEFAED4E9E1D" modified="2023-09-13" version="1">MMDPQLLLFRRQYLQLFEPDFLAWPPKQLLRDPAVQSWLYANLFNIDRNSKLPPERYQLRVLKPLLAKIEQSIEDPEEDEISDDLMSHLSTLITSGLPAESTAVQQKSYVTFTCLPPNQSGYDVEKVEPTVTLLERRHLISGSLTTGFRTWEAALHLGSYLLTPAGQNIIKDRSILELGAGTGFLAILAAKHLNAKHVTSTDGDEGVVEALKENFFLNGLDDEQKIFASILRWGRGLKGTWVEEDCEAWPYDVVLGADITYDKVAISALVATLRLLFEMRPSVHVLISGAVRNLDTFETFRHACLRSKFQVEELDFQPKSIREQTSLFYAKAVPLKILSIKAPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIR8</accession>
    <name>A0A9Q8LIR8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho guanine nucleotide exchange factor scd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762528.1">
        <property type="nucleotide sequence ID" value="XM_047904770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIR8"/>
    <dbReference type="GeneID" id="71985500"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05622"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000364">
        <property type="entry name" value="Rho guanyl nucleotide exchange factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
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</entry>
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                <person name="Chen L.H."/>
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    </evidence>
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</entry>
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        <source>
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    </evidence>
    <sequence length="193" mass="21612" checksum="F7339E511D8CBB93" modified="2023-09-13" version="1">MTYDDSNEEGTTNNQYIPIKPQIQCRKPWPRRAKGIWELLCIVLPVMMIAEVFVPGGGGAFVATHILFCIIGGTGLLFFIFADPTTGIPKKLHLRRLPDDGGDGSSLVEVVRMRPLLGWKRCEMIGGREPPKRAGIADCDGAYVVYRWRSWVGRIRWERALFVVGDGEAEDCTAAVMTRNGVPVTRLQWHRGE</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
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    </dbReference>
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        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
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        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
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        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="262" mass="30404" checksum="BCFC236188CD53C3" modified="2023-09-13" version="1">MMPPPASTPGSEHKWDPYGPNFLIVIGNGINQTIFNVSESFLSHYSGYFRSMSSTSSFSPIFPHNDAEIRLPGDDPEVFSMVLHYLHHRRFLDSTVHPSHIVSFDKIIDIWSFGEARIMPLIQNAAADLFANKIKLTKTLPDRWSIEYLWERTEKGCRLRKMLVAFIREMWIPDGHQHHIWGQLADGQSEDPERLVWLMEALLGSKHEIRVSAKTWRRLQSCEWHVHEDFVWCEGSEEASLDDQRDLPATKKHRPRSASWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3S2</accession>
    <name>A0A9Q8P3S2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A diphosphatase SCS3</fullName>
            <ecNumber evidence="8">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">FIT family protein SCS3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SCS3</name>
        <name evidence="8" type="synonym">FIT2B</name>
        <name evidence="11" type="ORF">CLAFUR5_00601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156554"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156553"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132023"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132018"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3S2"/>
    <dbReference type="OMA" id="FTSWFFG"/>
    <dbReference type="OrthoDB" id="5579088at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03231">
        <property type="entry name" value="SCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046400">
        <property type="entry name" value="SCS3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="342" mass="37659" checksum="C9308F372F3268E2" modified="2023-09-13" version="1">MATRRTTTRIDVPITANGNANANSKQSQPDLDAPPPTGSPFLPTTLEAALLALYPGTLLLGSLFSTLHPASRNATYLPYAQSYDPRDAPSYFAKKSNIFNVYFVKIGWIWITAAFFLFTLTHSSLGPTLRPQPTRRRLQAGARYACITLAWFFVTQWFFGPGIVDRSFRWTGGKCQQVAYEDAEDLARKVEAGDVKDVITHAACKAIGGQWRGGHDISGHVFLLIVGSAMLWLELLPAVLRMEGLREARRIFTADGLIRRVTVESDEPASSAKTPRDMGVGIQAALGVAALSWWMLLMTAAYFHTWFEKLTGLLVAFTAIYVVYFLPRGVPALRQALGMPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P496</accession>
    <name>A0A9Q8P496_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase OgpAT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756878.1">
        <property type="nucleotide sequence ID" value="XM_047900202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P496"/>
    <dbReference type="GeneID" id="71980932"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01054"/>
    <dbReference type="OMA" id="YQRKGWG"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051822">
        <property type="entry name" value="Glycosyl_Hydrolase_84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13170">
        <property type="entry name" value="O-GLCNACASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13170:SF16">
        <property type="entry name" value="PROTEIN O-GLCNACASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="24159" checksum="F6844D5BB802303E" modified="2023-09-13" version="1">MANSVEQLKIRPFLPEDEHQMFTIFSDTALQGLHDAGEESIRVRYHIWCRPYIMLCPQHCFVLDDNGLAVGYIISTADSASFVKQWLDQYIPFLQSHDIVRPGPDVDTTKEDSVAALREIAHTPGEQLLKDRDLVDTFPGHLHIDIRPRWQGVGMGKRMVLTFLDHMKRSGCAGMHLGMAASNASTGKFYERFGFEQYTKVEDGTIMVKSLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4B7</accession>
    <name>A0A9Q8P4B7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoporin NUP53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756938.1">
        <property type="nucleotide sequence ID" value="XM_047900841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4B7"/>
    <dbReference type="GeneID" id="71981571"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01693"/>
    <dbReference type="OMA" id="QGMICED"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="430" mass="46795" checksum="7AB83B816708FB56" modified="2023-09-13" version="1">MFNLRSSQQQRPLGMQVHAVPEAERYIDSTGRKLPWSYDTANTNADNEPAPQEKGPFGRSMRRTRSGASRSRSKTAEPRREEDRLKAENTAAEDLVFGSLRRAGTKDESKREALGEVDPNSQAASGRGADDEPTEVLLYGFGEDLQWSAIDFYERVSNGVILEDYERAPPGSRYDTSRTLGRAAAQKSISRAALRKKNKFAGGGHWIKVTFDTRGAAELAIARAPHTIKGHMVFAEFFVGHGPQKDEPVLATQAGAQITSDALPPTFSTLPQDQGTPEGSSATASSATATAPDGSRQGRIPPPPWNMALAGVVQDSPAASTSTMNGAAPQRPVTTSFQTQSQSQTVLQPRRGRIEGATRIEPLPAELAMAPKQPKASWTSWIGASEVIGSAVPRKQDNTFDWEVASFYWKLFYLLDQLLGTDFCGLRLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Y1</accession>
    <name>A0A9Q8P5Y1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758839.1">
        <property type="nucleotide sequence ID" value="XM_047902152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5Y1"/>
    <dbReference type="GeneID" id="71982882"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03004"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000026">
        <property type="entry name" value="3-hydroxyisobutyryl-CoA hydrolase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="7">
        <location>
            <begin position="63"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="55836" checksum="F30866687C983BCB" modified="2023-09-13" version="1">MLLHACCRRFASARPVTMPLKAKVLSPAMQQNAARTFASAHQIKELPGDEPNDVLFSNQGGVRNITLNRPRKLNSLNGSMARKIVPRLTEWSKSDLANVIVIKGEGRAFCAGGDVAWLAQRNKEGTEGQQESKDYFALEYKLDHLISTYRKPYVAFIDGITMGGGVGLSLHAPFRIATENTVFAMPETTIGFFPDVGASFFLPRMDGELGTYCALTSEQIKGVNVFYAGIATHYIHSSSLPDLEARLAELEFKDYDDLSHRHRIINRTIEEFVTGLPHDQPIGAPVGGNIRSAIDYVFQPALDIDGILNALEGLENMDPKTPGYPEVADWATKTRKTILQRSPTSVKVTLRQLREGKTWSMAETFRKEHAIASRFMEHPDFVEGVTALLVDKPKRTPTWTPSTLEEVSEEDVASFFNHRTEFDLLNQEAGSTGEDFKSYPHAWIGLPSENSVRKEVQQEKSREEILEHFLGQSHGKQGVKEKVEEILTRKAPQDEHGTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P671</accession>
    <name>A0A9Q8P671_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribose 5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759216.1">
        <property type="nucleotide sequence ID" value="XM_047907570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P671"/>
    <dbReference type="GeneID" id="71988300"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08422"/>
    <dbReference type="OMA" id="YPPFCLR"/>
    <dbReference type="OrthoDB" id="2106730at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1400.10:FF:000004">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="entry name" value="Sugar-phosphate isomerase, RpiB/LacA/LacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011860">
        <property type="entry name" value="Rib-5-P_Isoase_Actino"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051812">
        <property type="entry name" value="SPI_LacAB/RpiB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004051">
        <property type="entry name" value="PRK05571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02133">
        <property type="entry name" value="RPI_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43732:SF1">
        <property type="entry name" value="RIBOSE 5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43732">
        <property type="entry name" value="RIBOSE 5-PHOSPHATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="Ribose/Galactose isomerase RpiB/AlsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17139" checksum="5C4AC21A95BD5244" modified="2023-09-13" version="1">MFQQGLRIAMGCDDAGVGYKNKIKADLEADPRVAKVIDVGVNDSSDKTAYPHPAVDAAKLIKKGEADRALLICGTGLGVAISANKVPGIRAVTAHDSFSVERAVLSNDAQVLCMGERVVGVELARRLAKEWVGYKFDPSSASAKKVEAINEHERKNFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P748</accession>
    <name>A0A9Q8P748_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">14-3-3 family protein artA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04638</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760085.1">
        <property type="nucleotide sequence ID" value="XM_047903786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P748"/>
    <dbReference type="GeneID" id="71984516"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04638"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="231"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="29510" checksum="FD90901EF2C0B71E" modified="2023-09-13" version="1">MGYEDSVYLAKLAEQAERYEEMVENMKAVASADQELSVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGNEQQVTLIKEYRQKIEAELAKICEDILEVLDKHLIPSAQSGESKVFYHKMKGDYHRYLAEFAMGDKRKTSADKSLEAYQAATEVASTDLAPTHPIRLGLALNFSVFYYEILNSPDKACQMAKTSFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSSEAEPSGDAPAAGEGESKDTSDAPAGEEAKPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7K3</accession>
    <name>A0A9Q8P7K3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate-dependent sulfonate dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05127</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760343.1">
        <property type="nucleotide sequence ID" value="XM_047904275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7K3"/>
    <dbReference type="GeneID" id="71985005"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05127"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000008">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF9">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE (AFU_ORTHOLOGUE AFUA_3G01010)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="157"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="450" mass="50435" checksum="CD04B2E85B520B8C" modified="2023-09-13" version="1">MQPCEFSGKHSREDAAFLDNVHGWYAHQVMNSTLCFAWGKHKHSSLCQLTKGASRPFTQYCAITSIYWHTTVMAPAAIVPDIVDYVAPREDNLGLPAPTRVRLEKVGIDLSKGYPYRPAVPFYLQHVYAIRNEDREYVNAGTRASPSKKALFSAAKEVKHLTSHIGTEIVGLQLKDLTDQQKDELALLIAERSVVFFRDQDLSPQAQLELGRYYGEVEIHPQVPHVPGLPGTTVIWPALAATERAADFRNPVGTQKWHTDLVHEKQPAGITHLHNDTVPEVGGDTLWASGYAAYEKLSPNFRKIIDGRYAVYRSAHTYLARNDPHAGPKYIEREHPLVRAHPATGWKALYVNRAMTDRIVGLDKGESDAILQYLFSVYEGNVDIQCRFKWTPGTSALWDNRITMHNASWDYENTASRHGTRVTSLAEKPFFDPSAPTRRQALGLAGPGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7Y9</accession>
    <name>A0A9Q8P7Y9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760894.1">
        <property type="nucleotide sequence ID" value="XM_047904122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7Y9"/>
    <dbReference type="GeneID" id="71984852"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04974"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10540" checksum="D4EAE3DF6FE87B13" modified="2023-09-13" version="1">MVQASPTRAPRLEQESFWHTMRSSITEDAMAKAAKIGKSTRESCIYMSLVFVRAILTRADLTSQTRVEGGKLQNMSLDPTLGVEMLTDDDDACID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P826</accession>
    <name>A0A9Q8P826_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760999.1">
        <property type="nucleotide sequence ID" value="XM_047903353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P826"/>
    <dbReference type="GeneID" id="71984083"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04205"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="42"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="455" mass="50837" checksum="04535C7C6AEE7EA0" modified="2023-09-13" version="1">MKMRRQYLSRRRRQSARKAKAQTDAQIGNSGTGNRPGEPGNWVPWKRIGSGGQGSAWIWIYFNQNNAIIRRVVKKDTHCKDSWYDIRAWAGNDLKDYNSRIPWEHRCQSQLTWIANARHVVRTTMQWSPILVSEAWKSHKIYTEWCPMGDLADLITKYKEQPAPNNYIAEPMIWATAEALALAGLAMQHGTEDVDAGTLANWIPIIHRDLKPGNIFLADPSPNAQGTTLWPSYPKPLLGDFGLAIETSPTDPHNPTWHLELGTPGYMAPEQLAYIDRTTLFHLNPTPLTEKTNVFGIGVILYSLLTLNHGAASGIQPEFLGANPQDQNPFTLQDDEGDPYDQNNADKYTESLRGLIDECTHYDPALRPDFREILRRTRGLFDGPGDGLGVGASAQDLEAQADVFMSRGMRGGWAGATTRARYCLKNGDGSEWRKGDVYTVGLNRAALQAVVPQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8X5</accession>
    <name>A0A9Q8P8X5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762035.1">
        <property type="nucleotide sequence ID" value="XM_047905554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8X5"/>
    <dbReference type="GeneID" id="71986284"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06406"/>
    <dbReference type="OMA" id="EWCVWRW"/>
    <dbReference type="OrthoDB" id="433955at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF156">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="256" mass="27792" checksum="3527C5ABF9F54BCA" modified="2023-09-13" version="1">MGPPLRSFDIATDDNGSFVEVAISETPGLKAENLSLATWGSSFVLANLLHKWKSTVQHSTAAPIRADYNAIPVLELGAGTSLVGISAAAVWQVQGVITTDLAPLIRGLAQNISVNANLLKDRSASVSCGTLDWSEPDSLHVAGEHARVVDAKQTKAQIILAADTVYAEDHPELLTKTITAWLAPGPDSRVIFCYVLRHSYIDIIRDLWEQLDAVGLECIEEGQKDADPDKWDDVAPFEWCVWRWKGEAVGAEHGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P936</accession>
    <name>A0A9Q8P936_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762230.1">
        <property type="nucleotide sequence ID" value="XM_047905052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P936"/>
    <dbReference type="GeneID" id="71985782"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05904"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="49879" checksum="07F21960ACAE178A" modified="2023-09-13" version="1">MGWTNLRKRKRSDDDDGDGDGGLEAEVRARNACGRNSSKQMPGKTYRFNEEQREVPCCLLALPDDVLGRIFSYVLIKDEPIVVTKNTMDLSEELAEVKDSRGRTDIVPLERIALLGTCVRFRELSRPIFYAGNDFVVAVESFNATASTAWWNKVNNIRQLEAQVQTPRVITLESRHVPRPRLLFAGYRKPTMSSWIQQYHHTVTTARDAAPLTSGHISFDIDYVPNWVNLKYWLHAYYKDELPPYTIMTANAPTHLQGIAIAFNSIKAFLHWEWVDVAAQSLVNIRANLIIQDYRWEARSSRAQVVEIKEDEDSENIQEIGEDGVAAAMSAAKLEDDQACTSEALEESTAPSALDTRIEELAAELPDIEGRYLLHDRENEDEEEGEENEFKDKRDASNPHDEPSKPLANVSSNLNLKLRRSPRALVFVIPQTLWQRHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P971</accession>
    <name>A0A9Q8P971_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762214.1">
        <property type="nucleotide sequence ID" value="XM_047905696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P971"/>
    <dbReference type="GeneID" id="71986426"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06548"/>
    <dbReference type="OrthoDB" id="3636638at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="29233" checksum="3518CD354FEC32DA" modified="2023-09-13" version="1">MVSTKRSSRCLEDEDVASLRDAFDNKRLCSRLSMDDFLSFDGPTGIAVGPDGTRSDFFLHLGLSERNNRHRIIYRRMKQEAKNGMERLFDTRKSLQPEMVDDDSVQAPYNLKQITEWAFQRQVEHIYDNASINTRGIYDIIRTGDGSNWVIRWMLWRVIQCAQDRVIRATSSGGETECSTLTTCSTATDHSSVRTEETSPAYWPSTVSPHDFSDSDDWDPSELKSKVVRDEYVFTKPRLPQTPSKFWAHVMDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9E4</accession>
    <name>A0A9Q8P9E4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762439.1">
        <property type="nucleotide sequence ID" value="XM_047905476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9E4"/>
    <dbReference type="GeneID" id="71986206"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06328"/>
    <dbReference type="OMA" id="IRVKKYM"/>
    <dbReference type="OrthoDB" id="5571754at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="134" mass="15442" checksum="F371A079B1DCDE72" modified="2023-09-13" version="1">MSEGQVTLRTRKFIRNPLLGRKQMVVDVLHPSRANVSKDELREKLSTLYKVSKDQVSVFGFRTQYGGGKSTGFALLYDSAEAMKKFEPHYRLVRYGQANKIEKASRQQRKQRKNRSKEFRGTAKTKGASKDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9H8</accession>
    <name>A0A9Q8P9H8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762544.1">
        <property type="nucleotide sequence ID" value="XM_047905017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9H8"/>
    <dbReference type="GeneID" id="71985747"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05869"/>
    <dbReference type="OrthoDB" id="3650630at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="522" mass="56916" checksum="CAA013CD9B0301E1" modified="2023-09-13" version="1">MTWETLNQDVKARAMCAKCNKPRTSTPHQKKLFLVAERLSWETGVTPLSARSQNDIALWAVNAELDIYDPAVEDEDTVLGGKHSRDEPAYPFKSDEEAEFAMRIIAKAETLTRNSWEVWKAQADAALNVPPAKASTGPGSAAEPLDLTSDGPKTAVGKDSGQPPQNKQQDAVYKLLREWSKTDSILKTVLDALEKKVPLSPHGVQIFNLKVEAATKAVRGMSSTVAEPDVTTAAKGESPAVLEILAAKARDDPDFRALTMSVSKGVATAQMRALFQTHVLAARAATSEIRQPLQRISPNSTTQNVKGKAADREVPRKAPKKLCSYQTLKDFYGLLDKIERTSPMGAKYLEAYAERLQAESCKDCWFSKNVLPGLTEDEPEHLVKAAPTAPAVQHRASLTTARSAPSHAHGYVDRYRAQHGQNPPPHTMRHSAAEMPPRPPVAATERLLTTTGISREHSMGVPGPQWVPAHQQHVQLPTGIVFPTPEQLGLPPASQVPGKAQGTSSLRYVSPYATAPSRKDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9S8</accession>
    <name>A0A9Q8P9S8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent monooxygenase DEP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762637.1">
        <property type="nucleotide sequence ID" value="XM_047905218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9S8"/>
    <dbReference type="GeneID" id="71985948"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06070"/>
    <dbReference type="OMA" id="VWISAYF"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="487" mass="54441" checksum="088B9D3D1547DD1D" modified="2023-09-13" version="1">MIPEHYGITHEDHIPGRVLHKYLTDLSKKFGIFSRTRFNTRVESLEPTSDGGWKVVTTTNGEKEQTLHSKKVIVATGLTSAPNFPQYPGAETFNAPYFHAKDSCRQGGTVKTAKRAVVVGGAKSAMDVAFAYAAEGVPVDMVIRPSGNGPVWISYPHVMGGKRLEQLLHVRWMQWFSPCPFGGGDSWLGRTMRNFLHGTAIGRFLTDQFWAGLSGEVVTNNGYKTNAELGKLQPWNPAFWIASGLSIHNFDRDFFNMVKNGEVKVHSADVERMTDHTVHLSDGTEPKTDVLVCATGWRKEPSIRFLNFGTAGIGLPYTPTEQSSLATDYDDKILKMYPRLATQPTLNFKPKADPFRLYRFMVPPARIEDRNIAFAGMISSVSTTMVAAVQALWISAYLDGKLDHAPGSKEEVTKEVMLHTQWGKWRYPCGYGASLHDFAFDGVPYNDLLLKDLGVKANRKQGWKDVTEPYQPPDYKGIIDEWLELNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9V2</accession>
    <name>A0A9Q8P9V2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor lepE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762787.1">
        <property type="nucleotide sequence ID" value="XM_047906166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9V2"/>
    <dbReference type="GeneID" id="71986896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07018"/>
    <dbReference type="OMA" id="VYNQEMR"/>
    <dbReference type="OrthoDB" id="4236860at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="781" mass="87079" checksum="2BF65B0E56C41DCF" modified="2023-09-13" version="1">MPTDPLLPEGRNFPRTRSPDAAERDRKRRRKVLSCYDCRRRKLQCDRALPACSRCTKAGQAANCLYLEDAADIPLREEPQITPTDRAGKQPAFYGHSSRPIGASVGAIGDLLSRLEFQDGRIKQLEAALAAAGGSVKPRMPPTPDSFVGGSDPVAPIVDRETTLLRGRSFKTQFHGNTHPGALIARIPELHGFTRETFEQFPALSRIKEDMSSLENRTNYAGAKHGAVTDDELRALLPPKDAADVLVEIYIDNFGALYHIVHLPSFWEEYNNMWSEIQTTKAHFVALVLVMMSAAQCLTTAQPWVYRANSSTAREKAIAWIVAVDDWLIEQSQKHVEALDFQIRVLLQLAKQVVGRKFKRTWTDIGHVIRFCMAAGLHRTPDLIRKPTSILDKELRKRVWAAATELDLQASFDRGMVSSPWPSQSDCPAPAHIADDDLDQETSHMPALRRASDFTHVSYLSLSSESIMLRQSLNTYLNNIRQPVHFDESKRYTEEIESCLQSLPEWIGSSSAISYTMLSLNLRQYLLVLHDRQLRIAESKAERDFSRMILIETATKMLEQHQALTDKGIYALELLCYDQLRAALSLCHIASLNPQADDALSRAIDDTATRLIPAAIDMLTDKVIRFGREQRQLWILLAANGFMKSKKNPSNRLVYMQEAVDKITRPYYKIMACQEDAPVRTSAPAGAEGSGTRELLHGMSEYYPPTRVSNATHTGAGAGTAAGEFPVTDTAPLLDLDEIAAWTFEDWSFNPADLAAAFPEATYPHTGNTPFPSGSGAYPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9V4</accession>
    <name>A0A9Q8P9V4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Centromere-binding factor 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit cbf5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">H/ACA snoRNP protein CBF5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Small nucleolar RNP protein CBF5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_06856</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762802.1">
        <property type="nucleotide sequence ID" value="XM_047906004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9V4"/>
    <dbReference type="GeneID" id="71986734"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06856"/>
    <dbReference type="OMA" id="KYGRTNE"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="14">
        <location>
            <begin position="21"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="13">
        <location>
            <begin position="271"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="361"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="424"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00072225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO18436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="498" mass="55558" checksum="2A178FFA03297DFA" modified="2023-09-13" version="1">MSSTDEDQMIIKPEAATPAVDTSKWPLLLKNWDQLQVRTGHFTPIPAGCTPLRRDLKSYVSSGVINLDKPSNPSSHEVVAWLKRILRVDRTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCVLRLHSKLPGGEAQLARALETLTGALFQRPPLISAVKRQLRVRTIYESNLLEFDNDRQLAVFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGAMKEDDTMVTLHDCLDAQWLYDNQRDESYLRTVIKPLETLLTGYKRIVVKDSAVNAVCYGAKLMIPGLLRYESGIEVHEEVVLITTKGEAIAIAIAQMSTVELSSCDHGIVAKVKRCIMERDLYPRRWGMGPVATEKKKMKESGKLDKYGRTNEATPAQWRQEYKDFNDPEGVNGTTPAKAEQQAIEGAPVKEGIPGKGKEMPSKEDVEMAEPHDPATGETNGEKKEKKEKKRKHEGETAEEKAERKAKKKAKKEKKAKRESMVTNDSDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB22</accession>
    <name>A0A9Q8PB22_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763555.1">
        <property type="nucleotide sequence ID" value="XM_047906604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB22"/>
    <dbReference type="GeneID" id="71987334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07456"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="90673" checksum="E547D6D9B235028C" modified="2023-09-13" version="1">MHECPICHRTYQARTPLSRHIHNHSPDHLGRRHACETCGVSFARRDLLSRHQNNNHSGYMSSRRRTHTACDQCRKARMRCDGQMPCSACQERSKSCRYTDGRSRLSKAAPRIRLDSMPSSISSPRLLQTQDERQHDGDSQQQPLDGHAGPLLNETQEQPLDGLEGLLGQDQTEPHQIYTLGLPMDLDGIPWPWLHETSFLQDDPGLGDFGTVATHDYSAMLPAPESHDLCGDFRENDTVPDGQSHVAASSSHPVLEDARPLEAAEVDKLVHLASQPASGPGANAGGEDCFWDHVLFVATFIRGIATSAEQPLSAGDVFREHLQAYSTNFNRLWPMFVDSDIQAGRLHPILYLVQLSIGCMYGSPSAKHFGTLLHKSLRQLLTSFLAVESFDGDIIWLAHARLLTQVHGLYFGQPQGFSYAQHLGAVLVAQAKRLGLFQPTRQPGADLHGDYSGWKYAETRKRLALGVFRADVFTSVLLNTAPLLSFEEVSVTLPCSDDLWHNKHGLLAEALSVMINAEARQRLAYGLSDLSRILLDQSEKMPELDVSGYELAPFTLQSPIWKFSHDPALFPRLTGRHWKPVSHAFGVASQAQVTAPLDGLFSTTVYRRSSYTDALPDTPHDALGPIHRHMHDLVNDRARIKHALDAWHCSFTAARQMPASMDDRDTLMSSLLLWHTLNIQLDAPLKQLHDITYRAAAQRAVDKSTVQLVRDWIPTESAMIAVKAACVICEIIDSELTRSPGQRACFNFLAFSSLHHAAVILWTTTQSAEFGSFGTVVARDTSALLQACARLFRGLSPLGGESFGLAAERLMDCPFPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB83</accession>
    <name>A0A9Q8PB83_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763611.1">
        <property type="nucleotide sequence ID" value="XM_047906587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB83"/>
    <dbReference type="GeneID" id="71987317"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07439"/>
    <dbReference type="OMA" id="AAECKQN"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000003">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000004">
        <property type="entry name" value="Nucleosome assembly protein Nap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="348"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="45610" checksum="C61D3EBE2BA8EB68" modified="2023-09-13" version="1">MSQNIPQKGNAPAPTPQNTPANNAPISSHAQAPGISSIKEEDLDRAAAASIFAQNPRLVSMMQNKLSSLVGKSSGYVESLPAPVRKRVAGLKGVQKEHSKLEAEFQEAVLELEKKFFAKFTPLYEKRAKIVNGEAEPTEEEVQAGEEDEEEDEEAEAEKAEADKNAEGKEMKGIPEFWLSAMKNSSLAETITDRDEEALKFLTDIRMEYLDRPGFRLIFEFTENPFFTNKTISKTYFYQEENGYGGDFIYDHAEGDKIDWKAGQDLTVKVESKKQRNKNTKQTRIVKKTIPTPSFFDFFNPATPPENDDDEIDEDIEAKLELDYQLGEDIKEKLIPRAIDWFTGEALQFEQGMDDFDEDDFEDEDDEDEDDDDRDDDEEEEDDDEEDGNPKSKQEAAECKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBN1</accession>
    <name>A0A9Q8PBN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Global transcription regulator sge1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIT1/WOR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763871.1">
        <property type="nucleotide sequence ID" value="XM_047906320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBN1"/>
    <dbReference type="GeneID" id="71987050"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07172"/>
    <dbReference type="OMA" id="IEPPMAS"/>
    <dbReference type="OrthoDB" id="5319641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="530" mass="57063" checksum="BF494A72C51D43CB" modified="2023-09-13" version="1">MSTGGGAGPLVPTFHGFVHNSMDGLVLFEACLSGKLHHVPRRPHDRERSSLIKSGSIFIYEENASGIKRWTDGVAWSPSRILGNFLIYRELEKPFPPGEKKRAMKRKRTSMPGEPYPRRDSDDNEGPELNTPLTPPTPNVDGEVKPEIPSSDQDKELERSLIGSLVDSYGFRPDGLVKKTMSISVNGISHHMVSYYKVDDVKNNLLPRPLSDPRLQNISVRPELYLKQNFRAPVEETEHYAIDGHMNAHPQMIYSPMVQPYGMAPSQYMGARQYPGMYGSTTGSSMYGAMTAASWPTQQATAGAMGYGSHQSYGSQPYPSYYKPTDQGNGSGVKTESQHSTSQAMPYGSQYAPSYPNMQRSNSVSAPSMMQSSYQTPVQPHSSTFGTMGPGSGRPSYSGQSMNSPSANGQSQGPYGSASTAPYAVRSPTQSYSMQSAPQSAVSHSPHPSMKSPQSAHPGTSSDPNGQLHSGGMPYRSGSYAVPSAPQTGHSDMNGLGISSTSSYPPPSQNGSGYSYGSTGHAQTSGPYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCD4</accession>
    <name>A0A9Q8PCD4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA(adenine(34)) deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764245.1">
        <property type="nucleotide sequence ID" value="XM_047909188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCD4"/>
    <dbReference type="GeneID" id="71989918"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10040"/>
    <dbReference type="OMA" id="IDMAEFA"/>
    <dbReference type="OrthoDB" id="1701769at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052718">
        <property type="term" value="C:tRNA-specific adenosine-34 deaminase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000039">
        <property type="entry name" value="tRNA-specific adenosine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="158"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="222"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="32509" checksum="2B02955C96A3AA96" modified="2023-09-13" version="1">MVFGPIPNREYHERFMRKAIDMAEFALASDETPVGCVFVHNGEVIGRGINGTNASLNGTRHAEFVALAEIIAKHPQSIIKETDLYVTVEPCIMCASALRQYGIRAVYFGCLNDRFGGCGGVMNIHSDPGVDKSYPVYGGLFREEAIMLLRRFYVQENEKAPDPKPKKNRELKTEILPVTVTPLDQRGPRSPPIPIATPAMATPVLGAQSINQIVEKPLVRLPPANNSKQHPTAVPPKANTKQQPPQAKQNQPVKNPPTSTTAEKKKPKEKLPPPAGLRVEKPVPGAKGFAALGDEVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCP9</accession>
    <name>A0A9Q8PCP9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764472.1">
        <property type="nucleotide sequence ID" value="XM_047909475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCP9"/>
    <dbReference type="GeneID" id="71990205"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10327"/>
    <dbReference type="OMA" id="HTDCGGL"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175:SF3">
        <property type="entry name" value="CARBON DISULFIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="138" mass="15591" checksum="C4C0B03592AE1E22" modified="2023-09-13" version="1">MSEAVTKFQALIERSRKRLPTYQPPPQMKLFAHNDSHPGWIFMAACADSRVDPTHIFQLECREVNVIRVAGGRIRDDTSKSLEIMGTMVPIGLVVVVQHTDCGGLFTADDEIRKRVSARNPECAHLVKDSVWDTSKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEE8</accession>
    <name>A0A9Q8PEE8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765324.1">
        <property type="nucleotide sequence ID" value="XM_047910717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEE8"/>
    <dbReference type="GeneID" id="71991447"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11569"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="262" mass="29920" checksum="B3488FACCADF7D12" modified="2023-09-13" version="1">MTRLHPRSGTMPCAPLRIAVLECDEPIGRTFEKYGGYGNLFKELLENGVKRVKEVDGMEVPELDVTKYDVVKHEVYPKLEDVDAVLLTGSRHNSFDDDPWILKLVEFTRKVLAQERVRLIGVCFGHQIIGRALDVKVDRSDRGWEISVTDVKLTEQGRRVFKIDELAIHQMHRDIVYEYPKGIEPLGHSPRCGVQGMYAKNRLITVQGHPEFNADIVSELLINRHDKGIFDDAMYADGMKRVRNHHDGVAVSAAFIRFLLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PES3</accession>
    <name>A0A9Q8PES3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765620.1">
        <property type="nucleotide sequence ID" value="XM_047910048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PES3"/>
    <dbReference type="GeneID" id="71990778"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10900"/>
    <dbReference type="OrthoDB" id="3650741at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="151" mass="17592" checksum="A5AC73911509A870" modified="2023-09-13" version="1">MEITSEDLKRHLSSLPQELYDGIYERIFTADDRQIQTISRAWHAPHLLHVDRSSRQKFARSYFTTPSAFYMPHSNYGIEYFMLASWLAVLDDTHADMIQSISLGKNAMNPVWFLDLIHNLLEARLGAFYQLTAGHSAYRLLKKLRMAQELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PES8</accession>
    <name>A0A9Q8PES8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11614</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765501.1">
        <property type="nucleotide sequence ID" value="XM_047910762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PES8"/>
    <dbReference type="GeneID" id="71991492"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11614"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000002">
        <property type="entry name" value="External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000005">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 64 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF50">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="549"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO21135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="702" mass="78770" checksum="5861D2E4824F249E" modified="2023-09-13" version="1">MLPTCTQRALAGSARSSLLHAQIQQATRQHRPNAFAQTAQDAAKRAMTTQPPPPRQMLRTVRRNARQQAPTTKYIHARWASGRIEKATETVQPRPPSRIVQLAYKPAAALGLFVAISGGLVVAFFIFDATTYRDGPQAIDMSVSELALSPRKGGPKNLPIAEYFIDDEEDPDMLEQKHKPKLLILGTGWGSIAMLKQLIPGEYHVTVVSPSNHFLFTPMLPSATVGTLEFRSLVEPVRKIIRRVKGHFIKASAVDVDFSNKLLELESQDANGNKQRFYVPYDKLVIGVGSTTNPHGVKGLEHCHFLKDISDARKIRNRVIQNLEVASLPTTPDAERRRLLSFVVSGGGPTGVEFAAELYDMLNEDLTKFYPKLLRNEISVHVIQSRGHILNTYDEALSKYAEDRLAHDNVDVQTNARVKEVREDSILYTQKDSEGKTITKELPMGFCLWSTGVSQTEFAQNLAKKFDNQNNRHALETDTHLRLAGAPLGDVYAIGDCSTVQNNVSDHIITFLRTLAWEKGTEPEHMTISYNQWCEVAKRVKTRFPQANDHLRRLGKLFEQYDKDKSGTLDFGELSELLKQIDSKLTSLPATAQRANQQGVYLGRKFNKLAQAEYGMKLNEIYDGDVDEAAYKAFDYKHMGSLAYIGNAAIFDFNGVGWGGGLLAVYLWRSIYFAQSVSLRTRMLLAMDWSKRALFGRDMMNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF31</accession>
    <name>A0A9Q8PF31_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UPF0587 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765684.1">
        <property type="nucleotide sequence ID" value="XM_047910164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF31"/>
    <dbReference type="GeneID" id="71990894"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11016"/>
    <dbReference type="OMA" id="TAHFVWR"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="18353" checksum="69645DA292BFC208" modified="2023-09-13" version="1">MLAIAITAELEGVTDLQPEDTEQNPFYYTFKVQCTSCRETHPNWVSVSRFEQNEQSGSRGEANFVWRCKNCKREHSANIIDSPKSYPQQSPPKPQNILTIDCRGLEFVEFKPDGAWNATGMEKGTKFSDIDLTEGDWYDYDEKAGEEVSIKDIKWEICRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ1</accession>
    <name>A0A9Q8PFQ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766009.1">
        <property type="nucleotide sequence ID" value="XM_047908690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ1"/>
    <dbReference type="GeneID" id="71989420"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09542"/>
    <dbReference type="OrthoDB" id="3650897at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="75"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="154" mass="17016" checksum="6C24573C0A98BB43" modified="2023-09-13" version="1">MASTQTYIETPLVVDDDAGVTASMALSSLGESLRSAYPYMRTEALNNIVDHMKSELVSKITEQQPRMAASRARICFTDLPAEIRNNIYELVVIPQAGHTLLEIRTPRDATLSPRTYAKIPTLLATSRQVRNDASPIYYGNNGFIATFPYSATQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG39</accession>
    <name>A0A9Q8PG39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Alpha-dioxygenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_08884</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766340.1">
        <property type="nucleotide sequence ID" value="XM_047908032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG39"/>
    <dbReference type="GeneID" id="71988762"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08884"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031408">
        <property type="term" value="P:oxylipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09818">
        <property type="entry name" value="PIOX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034815">
        <property type="entry name" value="A_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF11">
        <property type="entry name" value="ALPHA-DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0925">Oxylipin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0611">Plant defense</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO21974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="628" mass="70919" checksum="D2D4E62EED646BE9" modified="2023-09-13" version="1">MDSPNFKPTLFERLGVRAFHLINSYIPWHRLPGLIGAFNLDFMRVELRNYNLHDGYANTEAQGKLGELPATEQRYVGTRNSDGSDNSLEMRKMGCTGMRFGRNFARKHCHKPTEEELWNPSPRLVSQTFMARKPEDFKPATTLNLLAAAWIQFQVHDWFNHEDSDQTYNIPLQKGDDWPAEHKPMRLFKTKPDEVQDASDERCPGYRNMNTAWWDGSQIYGSSESVTQSLRGCRTDGKLVLDSVGKEPHYLPRNPDGTPKTGFTDNWWLGVEMLHTLFALEHNAICDEIKQGHPRWTGDQIFDKARIVNCALMAKIHTVEWTPAILAHPALQIGMSANWWGIVGEKLTKAVGRISKTSEATSGIPGSGVDHHCIPYSLTEEFVSVYRMHSLIPDNIALFGAESGRHIGTVPTEDVTFTKPLDPFKAGVTFADAFYSFGINYPGAITNSNYPVFMQRLTTPDGQLRDMGTVDILRDRERGVPRYTEFRRLLRMTVPKTFEELTGGNKELAAKLSEVYGGDIDKVDALIGSHSEPLPEGFGFSDTAFRIFILMASRRLKSDRFIAGSWNAAMYTKEGFDWVQNSSLSDVLRRHFPELKAMLPEKTNVFAPWVKLPGSQEYAGIETNAPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGC6</accession>
    <name>A0A9Q8PGC6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08892</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766285.1">
        <property type="nucleotide sequence ID" value="XM_047908040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGC6"/>
    <dbReference type="GeneID" id="71988770"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08892"/>
    <dbReference type="OMA" id="HVQNADW"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
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        <location>
            <begin position="722"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="737"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="789" mass="90154" checksum="9491CBF9DB51C97D" modified="2023-09-13" version="1">MLRRPDTDTADAINSASERAVPHLPEIAVSRASSLASSRRTNGTAASKKIYQKRPAFPRVNTDHAFQPHWKPGYHHSETWKRAHQPDPEWRVKWSQHCFPKGRVLIIDYVSNESNVPDGGRRHITVATQEIQTLSELKRFYSDGKRVHGAALRVIHVQNASWATQFLLKKFNIDHPSELVGMKTFSRWAKYEKPRQRNGKPFPSGRSWRGQTDPWRKVSRAAFGLDYMKNFTTDTPHRRKRQTMAGEGPVDAKLMHLNVYEDNQHAPYGYATCVQRLSVYVQRNLGPPSRVSPDIDIKNPYARQLANGNGRVGAAKTDEVLLEYLDNGNTVIVFESSASMSLEDCIVQPRNEFENRWRRLSFYLRKEDVLNDSRLAAQCTNFIMVDLFHGLGVVWNQFLAAAADHVSLLEDKIYENPADESRAPELWMNQASWLKVDKVMWLHSDLAKEMQEIMYELANVDDEENGVEVDWMASTPAEFERLQHKVSEDLVQPTNNLSDLMYKSVGIRDSRQSLQLGLSMWRLSWITFIFLPLTFIVGFFGMNVDLFADDPGIGWYFVAAAILMLLVIILWYGVKHSLQRSRQTPYQRGLYEALFDNLEEEHPDLWTSAGAVDDVDPSQLSSSDRWRWRLLRRWFSPERTINKKLYSILTHDGSQSELGAWASVKRYLLVRWLGQIELRQPSIQSIELDQTDLSARVEARYESGTISELAKFSTTAAVAEAEPTAAEPLSSFGLRPLTHEDMRRQSEDRPSSRGSSGIIIEERNLSDSESDAGEGASKIYSSICRRASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGF6</accession>
    <name>A0A9Q8PGF6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766407.1">
        <property type="nucleotide sequence ID" value="XM_047907969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGF6"/>
    <dbReference type="GeneID" id="71988699"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08821"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021838">
        <property type="entry name" value="DUF3431"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490:SF3">
        <property type="entry name" value="DUF3431 DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11913">
        <property type="entry name" value="DUF3431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="237" mass="26885" checksum="2B4D636CEB93FBF6" modified="2023-09-13" version="1">MLWRRLIINNPHINSWLLASNHNGTTLDPRKISTPFKGPPLQPDGSPPASKHPKTTLVLATLASTDNSWVEEELGDLLGAYTNLYTAIYVVDDENAPLHTPANNGHEAMAYLTYLIEFYDNLPEISIFMHGHREAWHNNFLLEMSSSETIRHFHRDKVMRYGYFNLRCHWAPGCQPGFNPAATQYDNDKPEEMVIAEAWQTLFPSDEVPETLAQPCCSQFAVTREAVHAPLKQRTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGI8</accession>
    <name>A0A9Q8PGI8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_09718</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766363.1">
        <property type="nucleotide sequence ID" value="XM_047908866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGI8"/>
    <dbReference type="GeneID" id="71989596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09718"/>
    <dbReference type="OMA" id="ANEVIHF"/>
    <dbReference type="OrthoDB" id="3625086at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040375630" description="Extracellular membrane protein CFEM domain-containing protein" evidence="16">
        <location>
            <begin position="20"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="34"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="18">
        <location>
            <begin position="125"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="490"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO21997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="62450" checksum="47CCE3F06483CFC8" modified="2023-09-13" version="1">MRLTTAALAASFLPWTTTATHLDSRDVSFNSSTLATLPTCLLTCASTVLPKFDCHPGGSCYCDVGGPLKDALATCVAASCTSVEDQLVGIRLQAEVCGYPKHDDAPSTETVAYILFGVATVFLMARFVSRWPGFKGAGYGWDDWILLVAYPVAIGMTVTAHYAVFYGSGKDMYFLTANEVIHFFTWMFVGEPLYIVVTCLTQLSLVFLYLRVWPLQSVDDNSKFRMACKIVAWVLVATMLAFTISSIFGCRPVEAGWNLQLGRKAVCINRTASGYSLAAITIVIHIIVLLLPVPRLVKLKIPLGEKIGVLVTFLLGFVVTICSVVRMFYIYKTANVVNITYNFSFVGLWSLIEVYCTIICCCIPATAGLFRKLLGNESFKGLWTRSFTSMSRSRTTQTPIDREMDTMHRSYLTSPTYEMDGGYHAEAKVYKSSPQVESVESVATEAELYDRIEQAATSKDHTFDFGFYTGPNHENQAAGTRDADFWYKTRRSTPASSPLSSDATTKRKSTPEQTSPTPEFWFYDRPRKGSGDDTAVTPTMPTRPIPARFSSLQGLGSSEKEMGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGX0</accession>
    <name>A0A9Q8PGX0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766570.1">
        <property type="nucleotide sequence ID" value="XM_047907984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGX0"/>
    <dbReference type="GeneID" id="71988714"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08836"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040259406" evidence="1">
        <location>
            <begin position="24"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="11270" checksum="CB85ACA5B97A8346" modified="2023-09-13" version="1">MQYRTLLLATLAISAFAAPLAIANPNPALDLLTALGADPTGVGAALAAALPLVGAGAGGGAGNGGIGGGLGVGTTDRVAAQIASSTNPVAGGGTGSGVAVAAPGTGLGAGRGAGGNGLGGGVGGGSSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHI0</accession>
    <name>A0A9Q8PHI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ASST-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766888.1">
        <property type="nucleotide sequence ID" value="XM_047910971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHI0"/>
    <dbReference type="GeneID" id="71991701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11823"/>
    <dbReference type="OMA" id="HEPWDYF"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF9">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040133413" description="ASST-domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="77971" checksum="1C6CE13B9CB2A625" modified="2023-09-13" version="1">MTFSHHHTSHLGRAWIWTCILLATLFAPDVEAQLNNGTSPTHQFKSRPDLHAPIIDFTILRPELITPGYIFFAPFRNIDPGPYIYDNYGNLVWSAAGRSGPKTAHAPKVCQYKGTDHLCYFHGEQHQGFARGQGVILDQSYRVVKTVESSGAGASSDMHEFKITPHSNGTTALMTVYQPRQYDLTTNPRFNLQGGLGWVVEGVFQEVEIETGRVVFEWRSLDHVDLSQAWTLPGTTDTSGDGLHEQSPWDYFHINSIDKNYEGDYLISARHTSTIYKVSGKDGSIMWSVGGNSPTISNTNFKFSYQHHARWISENSTHTTFSFFDNASNAYNRTGEYSHGWIVSIDHTVKVATMIKEWGAPEAQGGLLSTSQGNMQLLPNGGAHIGWGEHAHFSEHTEDGTCVQYGKVANRASNVMIYRSNKFNWTAQPIEKPALWTYSRMGESDSTNEPESMRFWVSWNGATEVAMWNFYVSDSASGPWEYAGTAKKDGFETEYVLDKFAQWSYAEALNDQGRPLDASVIAKTFVPSLKLRQFCGDRGCEYAKKVPPEEVVPYHAENEVAKHDLSPNRGFNTKQYYMDIPLPEEMVPGSDINFDEEADEDEYCTGNGRKTKYNTKTWSSGSTTVAAGTGVMVGFTTAVIVFMLWRAGAFRKVHGKTSELMEEVAQTRFGSRTLGQYMRVRDSDGFESGYSSSSGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHW7</accession>
    <name>A0A9Q8PHW7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="14">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_12136</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 14">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="14"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767093.1">
        <property type="nucleotide sequence ID" value="XM_047911284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHW7"/>
    <dbReference type="GeneID" id="71992014"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12136"/>
    <dbReference type="OMA" id="MDIPRPE"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07857">
        <property type="entry name" value="STKc_MPK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000157">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="25"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="361"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO22727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="418" mass="48034" checksum="D3A6F6B8022E4ED4" modified="2023-09-13" version="1">MSDPTLQGRKVFKVFNQDFVVDERYTVTKELGQGAYGIVCAATNNQTGEGVAIKKITNVFSKKILAKRALREIKLLQHFRGHRNITCLYDMDIPRPESFNETYLYEELMECDLAAIIRSGQPLTDAHFQSFIYQILCGLKYIHSASVLHRDLKPGNLLVNADCELKIADFGLARGFSADPEENAGYMTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGSKPFFKGRDYVDQLNQILHYLGTPSESTLSRIGSPRAQEYVRNLPYMSKIPFQQLFPRANPDALDLLDRMLAFDPSQRIGVEEALEHRYLSIWHDASDEPNCPTPFDFTFEVVDEVPEMRQMILQEVRSFRQAVRAPQQQQYSQQQQQPQVPIPEGYDPRAYEDPRPQEMFQGHGQDLENELQNGIDAHMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI74</accession>
    <name>A0A9Q8PI74_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11777</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767263.1">
        <property type="nucleotide sequence ID" value="XM_047910925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI74"/>
    <dbReference type="GeneID" id="71991655"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11777"/>
    <dbReference type="OMA" id="PLNKFMM"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040345553" evidence="4">
        <location>
            <begin position="19"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="46"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="36674" checksum="BFCE97B59A1777B9" modified="2023-09-13" version="1">MKHVLLIAAALSFQQVAGAVHRLPVKYVVQPQQKVDGAQSHNRFFKQTDPDIAFQRDSSVPLIDSKTGHLFVNITIGDPPKQYEVVLDTRSSLLWLPDVECSSSAGLSCEDTFHIADLQVRDQKFVGAGDIPAQLGFDGVLGLGYSDASNDEALSPLENMIAQGLLDEPLFSLYLASDDDGQSEVLRGGIDETKFSESLVNLPVTGKNSWEVIVDTVELGSGSFDSKSMSAILDSGTPFIVLPTEMAETINKQIYHVGCEKLGPLPDLTFKLAGRDFEISPRDYIDQDGDECKGGIVGIDFDWFDNAIILLGDVFLKRWYSVFDHGNASVSLARAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIE4</accession>
    <name>A0A9Q8PIE4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cardiolipin synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11691</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767585.1">
        <property type="nucleotide sequence ID" value="XM_047910839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIE4"/>
    <dbReference type="GeneID" id="71991569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11691"/>
    <dbReference type="OMA" id="PSHKLLW"/>
    <dbReference type="OrthoDB" id="5193244at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040412024" description="Cardiolipin synthase N-terminal domain-containing protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Cardiolipin synthase N-terminal" evidence="8">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="11079" checksum="344B74207B49BA01" modified="2023-09-13" version="1">MLSLLLQLCLAALAFAAPTANEIHATSSNAWQYGTGGGVLGFIVLIIDVLVWMEVLKSNRPPLPKIGWSLLVFLFPIGGAIIYWLFANRAAHNQGAGYEPIGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJR8</accession>
    <name>A0A9Q8PJR8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768073.1">
        <property type="nucleotide sequence ID" value="XM_047912297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJR8"/>
    <dbReference type="GeneID" id="71993027"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13149"/>
    <dbReference type="OMA" id="EAINCME"/>
    <dbReference type="OrthoDB" id="10497525at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="25161" checksum="07599503703FBBA1" modified="2023-09-13" version="1">MPGQAEAHVGAQTQPETQTHDDNTLEGLDSLIQFCRVRLDSLRADAKQKRSDVVQAFHDHHAGLISTYDAGFIVGKYQGFLEVMRDITKPRYLAQLKLAAASSVIVLQLMHKIKVKKMADDSVKVGTLLSILTNRTSDSAPELWAQQREATKDLRDFLESVEMEQIEQWRQGRGKITLEQIAIRGQAAMTFVEVCAAREEAVDRLKKIREEYGEAFLANFDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKC7</accession>
    <name>A0A9Q8PKC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768386.1">
        <property type="nucleotide sequence ID" value="XM_047912031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKC7"/>
    <dbReference type="GeneID" id="71992761"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12883"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="13078" checksum="FD4287AD8DDF1B0A" modified="2023-09-13" version="1">MIYPAVASRLALVVSADYTNELGARAVGIYGTENAAGMTDKSLIKRKKNQKGKDKTKVDECALKVRSAKKDETQDRQKGKNKTEPEPAEEEEVQEEEEVEDEAECKEAEDEVEQEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKJ4</accession>
    <name>A0A9Q8PKJ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768582.1">
        <property type="nucleotide sequence ID" value="XM_047912608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKJ4"/>
    <dbReference type="GeneID" id="71993338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13460"/>
    <dbReference type="OrthoDB" id="3645509at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="83" mass="9130" checksum="5E8D045CC76E57C7" modified="2023-09-13" version="1">MAPASTSNEHNAPNGTADQHTATKACLMTVPSELRLEICPHYFPTFTFNTHAPASERGNFQAPLLNTCQLIRNEALPLYQTCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL49</accession>
    <name>A0A9Q8PL49_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_13597</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768882.1">
        <property type="nucleotide sequence ID" value="XM_047912745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL49"/>
    <dbReference type="GeneID" id="71993475"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13597"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="40"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="213"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO24516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="24780" checksum="D98B4134ECAE428E" modified="2023-09-13" version="1">MVELRKRPAAPPPPPPAKKRAPAKPKAKKDDAPKAAEPEPAEAAPAPEPIAEAAKGGAPKVGDSITLDGFGGEIETNDGDKTTLAKLVSDSQAGVVLFTYPKASTPGCTTQACLFRDSYEPLTATGLSIYGLSTDSPKANTTFKTKQKLPYPLLCDPNATLIAAIGLKKAPKGTTRGVFVVDKSGKVLAAEPGGPAPTVEVVKKLVAAAGGDAGADGIKKAEDKVSADTAGEVADTAEKLDGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLH6</accession>
    <name>A0A9Q8PLH6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxisomal biogenesis factor 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769086.1">
        <property type="nucleotide sequence ID" value="XM_047913074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLH6"/>
    <dbReference type="GeneID" id="71993804"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13926"/>
    <dbReference type="OMA" id="YEPMKEM"/>
    <dbReference type="OrthoDB" id="21292at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="34576" checksum="4313C68FAABEDE28" modified="2023-09-13" version="1">MAERPPQNVSAPDPEEDDLDDLDDVLDEFQATSISKPKAASPTVPAASGPGRPKYASSTAEPASAGSDDDLAKQLQAGMSSLISELDQNPDMQAEFEKMMQELIAAGAAGSDQEAGAHLQEAAKAVSEDTKPKATTTPSSSNTADKKKPAFDSTIRATMDRISASNTAASTASTQPQSEEDLLAQMMKELTEGGMMGGEGGGKGDFNSMLMNMMAHLTNKEILYDPMKELHDKFPAWLEKNEKTTDKENLKRYKEQQVLVREIVGRFERKGYSDGNEDDREYIVERMQKMQAAGSPPSDLVGDMSAAQEALGDLDQGCPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMK0</accession>
    <name>A0A9Q8PMK0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Norsolorinic acid ketoreductase nor1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO25132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMK0"/>
    <dbReference type="GeneID" id="71994177"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14299"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SDR_fam"/>
    </dbReference>
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        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="280" mass="30185" checksum="4CB26F49DB572CA3" modified="2023-09-13" version="1">MIQTRQISKCQASTTPSPLAIGHRPKESTNRTTYLVTGASRGIGEGLVASFLGRPDSTVIACVRNAATQSKALSELPHAEGSSLIVVKLDCAVETDPAAVVEELQSTHNIRHIDVVVANAAIAGAYGPTSTLPLDAVKEHMQINCYSVLLLFQATRPLLEQAAPGKAKFVFIGAPISTITQMEECARAPLGAYGLTKLAANYLVRKFHFENKWLMSFVIDPGHVQTDMGDSGARLMGRKEAPTTLQQSVDGIYLLQIDEATKEESSGQFLLHEDGSRLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMS3</accession>
    <name>A0A9Q8PMS3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769672.1">
        <property type="nucleotide sequence ID" value="XM_047913456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMS3"/>
    <dbReference type="GeneID" id="71994186"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14308"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040260911" evidence="1">
        <location>
            <begin position="19"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="15879" checksum="2A1B2B0EBBA79F03" modified="2023-09-13" version="1">MKFLLFFLVAVFLSLVGGVPVEPDGAGSALHQASNGVEDVASPTDKHFALLKNTCHSSDVSSTCIFYANNAAIELIELESEYKLEIWVAPSDRTTPKAEIDKWMALSNEIAEVVMKAVAELPRPHHRFVNTDRQLIELQQHCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQN7</accession>
    <name>A0A9Q8UQN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763320.1">
        <property type="nucleotide sequence ID" value="XM_047906844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQN7"/>
    <dbReference type="GeneID" id="71987574"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07696"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF84">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09170)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="50405" checksum="736F50033B505182" modified="2023-09-13" version="1">MTSSDPIKDGKGNVELHEVALDEKLAVVAVDKDGFGARKKVDPKEIKLVRKSDLYMMPTLWLMYFLNFLDRNAMVNGKLNGLATDLNLKGTEYQTCVSILFVGYLLGQVPSNMLLNRVRPSWFMGGFMMAWSIVSLLTYMCHNYTTMLVCRFLLGVTEAPFYPGALYMISMFYTKKEMATRMSVMYTGNMLASSFSGLIAAPIFSELDGHKGLSGWQWLFIIQGAASIGVAFAAVFLLPDSPLKTRWLTQEERLIAHQRIFDDQTGRRSEKSSVWKGLREACIDYKTWIFCLMDNLHLSANGFKNFLPSVVETLGFNTTTTLALTCPPYLVAGFISIAVSWSSGRFNERTWHTTVSKVIACVGLAVAAGTTSIAGRYAGIMIFVGATYGVNNIILAWSAASLGETDEKKAVAIAMTNTFGNIASIYTPYLRPDSSAPRYIPAFMASIGFSMGVVICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URB2</accession>
    <name>A0A9Q8URB2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763907.1">
        <property type="nucleotide sequence ID" value="XM_047906026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URB2"/>
    <dbReference type="GeneID" id="71986756"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06878"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="28557" checksum="B10FE713F88AACD3" modified="2023-09-13" version="1">MSDTPNIDAYLSSRRSGRRGAIYDEPDINTFGVSSGSSSRRRSTQADPLDSSYSSSYMSSSSGRRGAVTDNTYSGGYDSGYSGGYSGGYSDESSRDQIFREMFDESSRGSSSRRETESSRYSSFDSEGEDPFGNRRSSRRSRQEDTIDAYDRARGYDIGAGAREPSVYDAPTYRSASEYARGSVADPPSYYSRGTSGTYDPPPRYSSYDSRSSSREPTQYPPSRSRDYYGGGSSSYGGGSSSRRSDGGDADYYIRKWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URR5</accession>
    <name>A0A9Q8URR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10621</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764384.1">
        <property type="nucleotide sequence ID" value="XM_047909769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URR5"/>
    <dbReference type="GeneID" id="71990499"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10621"/>
    <dbReference type="OMA" id="TEYSCTA"/>
    <dbReference type="OrthoDB" id="5431405at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040215394" description="CFEM domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="366"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="197"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="282"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="694" mass="70440" checksum="D5EBA0F4B2EFE28B" modified="2023-09-13" version="1">MHFTTTAIAAAGLAAHQVIATGGYGGGWGGSGHYSTPDNTNNECTSEQSTGYNWSGLKDGSFDSYGSNKFSGWSCTNSFGKRDLLTKRSFQSKCISADLDKEPVISCDDDKTMSLDKFEVSSDQDADIECHYTMPDESICKEVHSCSARGTVIQNSQCGGAKSVTFKPAGDSKGKGCNIGVHSVGFNCGSASSTPPSYSSTAPPSYSTSSSVESVDTTSVPTAPAYESSSVETSSATTSSAIECGYGSTQSVPAYGSSTVCVAITSSSSTEEAPVTTSSTDSAPAYTAPAYGSSSSSTEGSPVTTTSVPTYSTGTVPSNNGTYSAPSAPGYGSSSEVSTVTTAPSYSAPASVTSAVPTYEGPKPESPNLLPKCLNTWMYLTTCKDNSDYSCFCKNAEFVKQVYQCVSSWSTTDDDTTSGASYFMGICAPYIPENPAVITACPSTVTPAATFSYAPISSIEGSPVESSAPASSPKTVTLYSTQINTVTSCGPEVTNCPAATQTSSYAIATTISTPEAPLTTAPASSSTEGSPVNSSPAVTPAASIPCTTITYSTEYPVPVTYTTGENQGNTIPSSSTTSTIITTVTVPQVQMTTYTVTQGSSTQEQPGLGYGTPVAPVTSAPGYTSAPTAPAAAPYPTTSAPGPVGPVGGGGASSGFGTTYVPAPSNSITPYEGAGGKVSISGVAFMVVVCALFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US69</accession>
    <name>A0A9Q8US69_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US69"/>
    <dbReference type="GeneID" id="71989803"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09925"/>
    <dbReference type="OrthoDB" id="3639104at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="28332" checksum="0D141428F1B09FA1" modified="2023-09-13" version="1">MWTALRGMYQRSAIARMVYTELRDSDGESSTGEETKSKLYHSTSSTLSKVAAPFAGLFLVAFILRLWSGPLLGVGQDCDCDTGDAIRWPNATGTNATLLTCGSSTAEALTSGCMFELWSFSWIPEPCFDADLHDEFLKTWPSREPVIGGYYSDVKGSVQIPLENVLQGTANGSFTTWGQHYWHCAFALRKIFRILEEENLAESMSLMTALDRSTHHLNHCEDVVANPLKHDWKYIYSEQYIRFRTCRGKIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USJ4</accession>
    <name>A0A9Q8USJ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765213.1">
        <property type="nucleotide sequence ID" value="XM_047910176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USJ4"/>
    <dbReference type="GeneID" id="71990906"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11028"/>
    <dbReference type="OrthoDB" id="10264507at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="71" mass="7890" checksum="007171E7C4B1BE5F" modified="2023-09-13" version="1">MAWVKTDHTIDMSDADLSDLGPPFAVQLVRQVNFGPLESKRYFIPTAGQDGPFKEITEGDLVHANFQKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USW3</accession>
    <name>A0A9Q8USW3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765584.1">
        <property type="nucleotide sequence ID" value="XM_047910108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USW3"/>
    <dbReference type="GeneID" id="71990838"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10960"/>
    <dbReference type="OrthoDB" id="3650741at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="18695" checksum="E31EC5764D1B20C6" modified="2023-09-13" version="1">MPSISSEDISRLLGTLPQELYDEIYSLTFTADPGVRKVNKDWRRPPHLLLVDASSRALFAKSYFDADSSFIVRAVGTGPKCIASDETMARWLARLGKDHVALLRDVRVGTTAQLPYTNEFRVWVRDFLNYYHKCEAGHPAYKVAERIEFITEEKARELEAGGAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT38</accession>
    <name>A0A9Q8UT38_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765751.1">
        <property type="nucleotide sequence ID" value="XM_047910042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT38"/>
    <dbReference type="GeneID" id="71990772"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10894"/>
    <dbReference type="OrthoDB" id="5286775at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="473" mass="53085" checksum="6CBB8AB7F2E97B35" modified="2023-09-13" version="1">MALLKRLSDSFWGYVSPQKQTQAPALPTPKTEPTFKKPDRPPRRTSMHELKRGAPSMSPSERVGSWQVRSPGPSSRASSSATGGSKRKRLSTPESSAGRGRKHKMPRVDLQYTGIEEDEDVEDHGGETAIHEDELHELADRTSRMRSRSSTPRSQRHRSPSLEAEDFEDDDMSIEKTVVVSEDQYAPLPRRVIDLPKEHGMRHISTEELRAQGWDDDYITLIQKIGMRGYEPLLPRYLKFEYIFLPDGLFEATDEAFIGSVRGYKPGAHFKAGKVLTRLLELGSRVRDRAELIADGEGVVEPEEQTRKQLNAFLKWAFEDAQIDKATAIPILATVFRPAGTEASELRTEATRKCRRLAARYREALRVQRSVEVSPGSRSSVGTILSYELPTFYALVASHSIVALMAYRPGDVNAEVKPMAYFDLGEHDHDVWNALAIAILACHVRDVHMRIAEDTGLGKREGSSESSFDDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTA9</accession>
    <name>A0A9Q8UTA9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766037.1">
        <property type="nucleotide sequence ID" value="XM_047908742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTA9"/>
    <dbReference type="GeneID" id="71989472"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09594"/>
    <dbReference type="OrthoDB" id="41200at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="3">
        <location>
            <begin position="169"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="721"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="823"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="858"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="898"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1073" mass="116652" checksum="7C2C68A839331B73" modified="2023-09-13" version="1">MADTRPEVADAGDNAPVAVPDESAVDDPSSVKKENAEDTPSARTSSTTSGASALQRLTDTALDFLSHASNETLAACLVGLGATTYLVLGRVGLVIIGVAGGVVLKTTWEGIRYGHRDEATKKAEQDRRREAGVEVARRVLEWRRSGQDDVKAADARVYANQALDYSAFQPETAAALNTFTDAVIKDYVHYWYDPTLPGEQSFPDACRQTFTAFMLSLSGHLGRKRPADAFLDFVTNATSIIIVFLQELSVALNASPNTPPQEAIRAYIKLKPDCSLAYMLDQESQKLKLADASEDILQSYLDPKSYNCPPVHVFLKQVLAQLVLGYTVEMCSKPEWINDWIVYGLEESETTKEVMDIVDAGVEGRAQPDTPKIDEQISKGVAEVKSKKEGAARSSTDTASQKAHRRKMSKAEEAMDEAMQEARRLTEMMIEEDRRKADNDQQRQATPTIAEDSSDGATQGAPTPSSSQSGQDRAEFESMTSGDDSSIINGKPSTPDTQFTSFDMLVPNAVPTALAGESPVHSPARPSPAVLTLHNATIAIFDDGDPGKGSIKSRPDWDYLLQIEPASSAFPGWMMARKYQDFEMLHEVLRRISVITGVQFTWAELPKWKVHTKASLRTELERYITDAVRYQPLAECEGMKRFLEKDRGLNKSPGASKGFGWPTPDAFGKIGGDMMNVLTKAPKQVAGGGNAVFKGVAGGGKAVFGGVAGLVGGKKAGTSQVNLTRSTTNASLSGTTDESHKPRPSISTRQSFQTDGYASSTEAGRQSQDSFRVVPQAVQETRRGSAATSASVESRPRPSTTVSRPESIVSHPELGHTAEILPSPTTSTEQLPANASIYESINLPPPPSEMPADYDAPSSPSRKSTDTFRSQRSTNLDQRLAQSNGADDFAPATPPRPAKQEPKKKEPLSERETSVAVELMFAVISELYQLSGAWQIRRTLLTAAKTFLLRPGNPQLGSIRDLLQTSMLDANLNDSGLAHQIYKLRENTLPTAEEMEIWKRDYPEKTDEQKEELRTKARKLLVTKGMPQALTSVMGAAASGEALGKVFDCLQVPEVSRGLIFGLMLQALRVVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTL5</accession>
    <name>A0A9Q8UTL5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766367.1">
        <property type="nucleotide sequence ID" value="XM_047908322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTL5"/>
    <dbReference type="GeneID" id="71989052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09174"/>
    <dbReference type="OrthoDB" id="3642924at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="17160" checksum="8CE4B4161DF6847C" modified="2023-09-13" version="1">MGNNSSIPSQTCRFFDLPAEMRNEIYFLTLKHDRQTGSKATPALLRTCKQIYAEAIQVLHAQSMLSIKIDHWYSSFLKDRKIVVRMVYIIYYGTSWQSAFCYSLGLCKPLPADTMRIRNLHLYFAHSPYFENRICMNAGRSSETVTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTS8</accession>
    <name>A0A9Q8UTS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome regulatory subunit rpn3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766605.1">
        <property type="nucleotide sequence ID" value="XM_047908555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTS8"/>
    <dbReference type="GeneID" id="71989285"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09407"/>
    <dbReference type="OMA" id="AKVYFYF"/>
    <dbReference type="OrthoDB" id="1713558at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:enzyme regulator activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="CSN3"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="250"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
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        <location>
            <begin position="475"/>
            <end position="505"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
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            <begin position="475"/>
            <end position="488"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="505" mass="56712" checksum="6906D8C85D0BB5AE" modified="2023-09-13" version="1">MADKMDIDAVNAEKQEESVGPAPDLPPERIIINNLHFINQAVDNFDSRFTLRALRSIATLRKSDKFAEALVVGIRTAYPKASNKGRQILEELLPESHQANGTAAGKEKDTAEEQTHPEIWAYLGVLVQVYLYDNGEFEKGADFSENFIERIRSWNRRTLDQIGAKAYFYYALFHEELDPKPPSKQSPVIDTRPKLLAALRSAVLRKDTDTQAAVTVLLLRNYISTADITQADLLVAQTQFPTSASNNQVCRYLYYIGRIRAIQLAYTQAHDHLESATRKSPTNGPAVGFYQQATKLLIVVELLMGDIPERSIFRQPALESALYPYLKLVQAVRVGDLQAFLKCVSLNEQQFRKDGTYTLVLRLRQNVIKTGVRMLSLSYSRISLRDICTRLGVDSEESAEYITAKAIRDGVIEASLDHQNGHMVTVPQKDAYSTTEPSDAFHARISALLGMRDECVMAMRYPMNKNRQELAEAAKARDRERELAKEIVEGEGDIDDGDDGGFEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTU6</accession>
    <name>A0A9Q8UTU6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Flavin carrier protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09643</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO22195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTU6"/>
    <dbReference type="GeneID" id="71989521"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09643"/>
    <dbReference type="OMA" id="KSYWWIF"/>
    <dbReference type="OrthoDB" id="2115177at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
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        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF5">
        <property type="entry name" value="DUF907 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G06100)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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            <begin position="23"/>
            <end position="736"/>
        </location>
    </feature>
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            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
    </feature>
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            <end position="461"/>
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            <end position="543"/>
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            <end position="574"/>
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            <end position="615"/>
        </location>
    </feature>
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            <begin position="24"/>
            <end position="170"/>
        </location>
    </feature>
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            <end position="736"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="736" mass="80287" checksum="C4401F0CCAEEFDE0" modified="2023-09-13" version="1">MRSFGPYIPFILAGALPVSVLAGDILSTTGVSTCISDPDITVKTLNVEYNRANRKIIFDVAGSSAESQKVLLNLVVTAYGREIYTKDFNPCDNSTGISEDAMKQMCPIPAGTFASQGEQTVPEEYASKIPSIAFQVPDLDGLVKLKVTNAESGNELGCIQSSVGNGHTANLPAAQYAAAGMAAAALAMSAIGAVASVGGAGATSPSPTFGEVIGWFQSMATNGMLSVQYPKVYQSFTTNFGFSCGLVQWGAMQNAIDNFRAKTGGNTTDNSYEYLKNNVTLVYNDGTNSSVSKRALSAATNILLARDGVTVDVNGTSQDVGDSTISNSTSSADSKDQRFVSGLQAYAEQLSIPSSNTFMTILLVWAIAVAAIIVLILVFKAILEVWAQFGKLSPAMESWRKRYWWRMAKAITNLMLLLYGVWTLWCVYQWSSGDSWAAQVLAGVTFAIFTAVLAGFTWKIWSKARAAKKMEGTTDKLYDDKDTWIKYSLFYDNYKKSYWWIFIPTIIYMFARGAIIAGANGHGLIQVSGQLIVEALMLCLLLWARPWQRRSGKWINIIIQVVRVASVVMVLIFVEELGISQTTKTVTGVVLIAVQASLTGILAILIAVNAIITCVKENPHRKKRKEQEKLERDLDNLTPLHARNSLLMDPMVQKFPDTSYKAPLVAASPFADARGRYDPVQNRDASPAGRYRDDEALMPAAAPFSHHDQERSMHSRSPSVESRQPRLPDLQFGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU20</accession>
    <name>A0A9Q8UU20_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766728.1">
        <property type="nucleotide sequence ID" value="XM_047908327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71989057"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09179"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053268">
        <property type="entry name" value="Woronin_anchor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641:SF2">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40641">
        <property type="entry name" value="INVOLUCRIN REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_2G08060)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="7164" mass="777746" checksum="831AB2762682E6AC" modified="2023-09-13" version="1">[encoded data, 7164 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVM5</accession>
    <name>A0A9Q8UVM5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetrahydroxynaphthalene reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12822</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768494.1">
        <property type="nucleotide sequence ID" value="XM_047911970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVM5"/>
    <dbReference type="GeneID" id="71992700"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12822"/>
    <dbReference type="OMA" id="EYACTWS"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05362">
        <property type="entry name" value="THN_reductase-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="33012" checksum="0FF6570202F46FF4" modified="2023-09-13" version="1">MSNNTADTSTNEPKRLSIDPLGAIAKYNALTAHFLNPTLPTTMSASQAVETSRLDGKVALVTGSGRGIGAAMATELARRGAKVVVNYANSAEAANQVVDQIKKNGGDAIAFKADVGDVAQTTKLMDQAVEHYGQLDIVCSNSGVVSFGHLKDVTEEEFDRVFRINTRGQFFVAREAYKHLSVGGRIILMGSITGQAKGVPKHTVYSGSKGAIETFVRCMAIDCGDKKITVNCVAPGGIKTDMYHAVCREYIPNGDKLSDDQVDEYAKTWSPMQRVGQPIDIARVVCFLASQDGEWVNGKVIGIDGAACM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVX3</accession>
    <name>A0A9Q8UVX3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768797.1">
        <property type="nucleotide sequence ID" value="XM_047912900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVX3"/>
    <dbReference type="GeneID" id="71993630"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13752"/>
    <dbReference type="OrthoDB" id="3649915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="46327" checksum="9C07A22EF326D898" modified="2023-09-13" version="1">MTQRLSSSSSSPYTMTRGADSRISRSMSIGDTYWRLRTYRGATIGDLRKRAQNANYHIKKSASLGETIAAVHRLDRGLVSYANCTLQELRRFHEDRGLGKAPKLGQRILIKALDSADDNATFTKLLDLPAKLRCCIYDFYIDGFQNDTLWDPTHPPLSQTYKLIRSEFLPIFFGTICFQLAFQSTTWGHEAPHRYRLRYETQLFLGSLQPENLATMSRFNVDFTHGSGDFSNVKLRLNKAEKVWAVEVVPNREPNVFGLEAMERIEKEARKGFHGDEGEAKSLTMDDLYAVRKRVDERGFHNFTPPSYQFLASLGPQNLAQISSFEMVFYPRTRLVAKLDKAENVWHVSVVLELSRWSSDVSAAAQLEKDVRQVLGGDPDEAKPLTLERVYSTRRNVESAFPVACAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW78</accession>
    <name>A0A9Q8UW78_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769094.1">
        <property type="nucleotide sequence ID" value="XM_047913181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW78"/>
    <dbReference type="GeneID" id="71993911"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14033"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="20616" checksum="5A1DE0212DE4C5E1" modified="2023-09-13" version="1">MAELIASQSRSLLDLPPEIWSHIGRFAVDEAPTLSTWVLRDIQDCRTIRARSAVIKSTEQPPITRTCRALRDELLPFYYRSKINIQLEALGIPWVVLRPTPDYRLLVAWLWAIGKDNRRNVRGVCRRFITRGPYASTHMEVLKERLLEAMGEQWQIEAELVEVKVEHSTVQYMVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWE1</accession>
    <name>A0A9Q8UWE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769274.1">
        <property type="nucleotide sequence ID" value="XM_047913393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE1"/>
    <dbReference type="GeneID" id="71994123"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14245"/>
    <dbReference type="OrthoDB" id="10421064at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="581" mass="63843" checksum="D0EF5C42E1E5B93E" modified="2023-09-13" version="1">MTMERPSSVDEGLHRVATEDRRGRFARLRLSIPKALTPLRRTKTASRRDVSPGSDAASTRAICDGISPSFYRMKRVSKHLCEPSPALMQFATPANGVSFARSSSSDTISSLSETDRSPASEDTSPASCIDEGMPSMVRPGILPDVSPDKHSFEENVTFRDDGTIAKLWADYCVNQTQLKSYEAVVATAAAAELLEPRAGASILTPGPVEAVDRFPLSPRERSDPFQTGMESPAIDKMFQYSSSSLESYNTKTDKAMNSTNEKAAPMQIKTNQASELGKPWKAKKSSRDSSHCDNTASRSEHNNWKDLEWHEKRRERGALASELSLWNFDDASKNRHKTPSAAYGPKWEVSTPTDLSGLAQEDDYFSQRKPTGCRLRTSVTPNLTRQEDIIEHIKDKFQAHHDEMDARANTLSYSRPCTGRPGRDFSSGEILERENNSFSSEFNRSRDMRDSITDRALSGSPRDSKVCRTTIHADLSPPLSRGVSIGLPDCSQDPMVKAAGCEKVSSRSGSGTTSKLSSRGQSFGVPGYERNRGGKAAVDEKLASRASQQQSAQAGLVKVRQSNEETLQLGGKDGRSNNDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXL4</accession>
    <name>A0A1P8YXL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative effector 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CE43</name>
        <name evidence="4" type="ORF">CLAFUR5_11716</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943075">
        <property type="protein sequence ID" value="AQA29246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXL4"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671804" evidence="2">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQA29246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="21056" checksum="A0AEA6BEA8047EA8" modified="2017-04-12" version="1">MKTAFITIFSLCAAFGLAAPANDEYDAANALVARDGGEESTCCGGSGWAGYDETAENGKKSGKQHKKINEREAEAEVELVTPNVLALRWVDSAPKREAELEARDGGEESTCCGGGGWFGYDETAEDKKHAKVDGKHEAGKNHKPVQPVQEEAAEKREAAIEARSPDGGEESTCCGGSGWAGYDETAEDKKKHKHVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5M8</accession>
    <name>A0A9Q8L5M8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase bli-4, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755711.1">
        <property type="nucleotide sequence ID" value="XM_047899231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5M8"/>
    <dbReference type="GeneID" id="71979961"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00083"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF33">
        <property type="entry name" value="OXIDOREDUCTASE BLI-4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="375" mass="40889" checksum="6764740061F3201E" modified="2023-09-13" version="1">MIPIFRCARLAKFTPTLTTPLRTPTRTTRASFATMSSTLDQVKSTFSQNLGGVAEKLTPAGQNFSIDDIPDLSGKVAIVTGGSEGIGYACTHTLLSKGVKKLYILSLSKDVVDGAKEAVASELGQEKADATEWIQLDISNWDKTIEVAKKLAAENERIDILINNAGRGIMTMELTDKGVDRHMATNHMGHVLLTSYLLPTMKKTANAGNIVRIAGLASNTHEQSPKDTEFESLAELNQDHGPLAQYGRSKLAVILYARWLARHLTKEYPNILASATHPGVVNTKMSTEDIHEPYPLAGYLMSTVARPFKKEPFEGALSTLYAATTTKNSGEYVCPPAAIEPGSELSRSTHLQDNLMRLTQKVLKEQGGLEHVIFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5N8</accession>
    <name>A0A9Q8L5N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755650.1">
        <property type="nucleotide sequence ID" value="XM_047899462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5N8"/>
    <dbReference type="GeneID" id="71980192"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00314"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="30858" checksum="203366BFF1B6A7A7" modified="2023-09-13" version="1">MCQYNIDRWVEETRLTIEPSPAPPGPGAPNTDWRIPITRRYYAQFLLPRNTDPRGLLPVPGPPHPSRLNVPLRPLNWRRGRHLPHVSTIPTPQLSLETTSSLERLDMPGHYLHSIDYLIVSSPARPPQTPRANTWPPADLTPTAESFTYNVTTPPDEASGSSNSSPHSGSYVSGMSIAPLTPLPTPGMSRRNALPVRDPGLPDSPPPRRDNPGGDAGSDDGSGVWHDEETHGVADYDEGDIERARNPPPESPDISPRTAPSTARASRFVENMDVSAPEGYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5V8</accession>
    <name>A0A9Q8L5V8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome b561 and DOMON domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755733.1">
        <property type="nucleotide sequence ID" value="XM_047899483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5V8"/>
    <dbReference type="GeneID" id="71980213"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00335"/>
    <dbReference type="OMA" id="VANIHCG"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040180965" evidence="9">
        <location>
            <begin position="20"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="10">
        <location>
            <begin position="298"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="528" mass="54829" checksum="90B6F813C8098E4A" modified="2023-09-13" version="1">MKSFVAALTALSLVPIVSAQSPAKTCPESDICFQLNIPEATASSGTGDIFFQLKAPTTYQWVSLGQGSRMSGSNIFIMYTNADGTNVTLSPRLGTGHVEPQHDTNAQITVLDGTGVSGGMMTANVKCSNCDSWSGGSMDFSSDSSQWIYAYKKGEALNTDDLDASISQHDGASPFSWNLASAKGGDSANPFMAGSGSGSGSGTGTGSTSLPPCAGTAAATATLASLTATGSNADAKGCPTAYPTEFSAAWPTARPTWAASCFPSGYGSWPTNAPWRGGSNNDKRQEAQACVNEDGSISNSQPGDGSGNGSSSSASFKNAGVPFGGNYQKANNIILAHGVLASLAFLALFPTGGILIRIASFTGLIWVHAACQLLGYMIYIIAFGLGIYYATEMDLTSNSHPIIGIALFILLLIQPLSGLLHHKLFKKHETRTAWSYGHLSIGRIAIVLGIINGGLGIRLAGDVSQGGKVAYAVIAAIMGLSYLASVILGERRRRRNAPPSYSISLKESSHGAPALYSDAGYVHEHYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L615</accession>
    <name>A0A9Q8L615_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="1">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="1"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755844.1">
        <property type="nucleotide sequence ID" value="XM_047899425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L615"/>
    <dbReference type="GeneID" id="71980155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00277"/>
    <dbReference type="OMA" id="LFRICAR"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF45">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG8306-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="2">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="44410" checksum="0136238532CC7758" modified="2023-09-13" version="1">MASSLPDEYGFYFQDKAIFLTGATGNLGSCILYRLITQLKPKRVFAFVRDSRTQAIEKLRNKMLGYADVLSQSDSIHYAVGDLRLPGLGVDRTARQVLEDEVNIIIHTAANLSLLDPVADCMKNHCDPTLELARMATRFKKLQRFVYVSSAYANSFLPDGLVEEKVYPLLDSSGEDIDPEFEREEIDQTDSSSFTKPFAWPYALSKYLAERISLTRYSSLPLLIVRPSTIGPALQTPFPLFGTVESCPMQYAAKIYLRDPQASRVWHAPAGASSGTNVLDEIPVDYVSNALLLHVAAESYGIVHATARNYAQLTVNDTLMHLMHAGGSGASEDIDIEWISPKTGPQCALANLFVVGNRDWDFSCARSEALMQDANLAGSSCYQGAGVCFQSTTFARSKRRGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6J6</accession>
    <name>A0A9Q8L6J6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756015.1">
        <property type="nucleotide sequence ID" value="XM_047900498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6J6"/>
    <dbReference type="GeneID" id="71981228"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01350"/>
    <dbReference type="OMA" id="ESESCKQ"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="150" mass="17584" checksum="CB95D4D19BD36E2A" modified="2023-09-13" version="1">MARTRQTRKKLKTVTELPPKKCQFFTLPPELRLEVYKLVLADFTIDPSERKLRELPLVQVNVAIREESVGIFNKRLSAILDERWADLTDAQLESESCKQRYDLGLGSRRAGLRRWTAAMDRCNHIMDSIERDQIAVKIERKKLRKEGFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7G5</accession>
    <name>A0A9Q8L7G5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL2m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00116</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756687.1">
        <property type="nucleotide sequence ID" value="XM_047899264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7G5"/>
    <dbReference type="GeneID" id="71979994"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00116"/>
    <dbReference type="OrthoDB" id="268576at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000034">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000128">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 11" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="10">
        <location>
            <begin position="110"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="9">
        <location>
            <begin position="213"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="321"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="378" mass="41451" checksum="57B475A053A7ECC5" modified="2023-09-13" version="1">MMLQPRIQPRAVCTSCKTLLSSFARLPALSTRTYATRTESTSASSSTADVTAFTPASAGPMRKQSGFQLRTYKPRTPGLRHLRRPINDHLWKGKPYAKLTFPKIGHGKGGRNNTGRVVMRHRGGGHRRRIRTVDFTRMEPGKHLVERIEYDPNRSAHLALVESVKTKKKSYIIAAEGMRAGDAVESFRLGIPRELLASMGGVMDPGMLAAKTALRGNCLPLHMVPLGTQVYCVGSTPGKGAVFCRSAGTYATVIAKEEHGKKVVDVTVRLQSGEVRKVSKDACGTVGVASNPHWHFRQLGKAGRSRWLNIRPTVRGVAMNAVDHPHGGGRGKSKGNVHPVSIWGTPAKGGYKTRKKNNPNNYVVQERVRNQGKRRSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L856</accession>
    <name>A0A9Q8L856_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450 monooxygenase psoD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01699</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756932.1">
        <property type="nucleotide sequence ID" value="XM_047900847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L856"/>
    <dbReference type="GeneID" id="71981577"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01699"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
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        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="20987" checksum="A90371ED938E252F" modified="2023-09-13" version="1">MRQNNRSRPTPTPLRLTPSWTKTFLENQTSLGFSNRLEGAHAIGMHGIAGALTIAAPMQSFCLAMTHHAQFQHILHEEIDRVVGDSMPTLADVPNMPVLRAFIRETLRWRPLIPTGIPHALEDDDVYEGYHIPKGTVVHPLEWSISRDPKVFPQPEEWNPMRWLEEQYPTYRKPLTTHPTITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8B8</accession>
    <name>A0A9Q8L8B8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757121.1">
        <property type="nucleotide sequence ID" value="XM_047900072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8B8"/>
    <dbReference type="GeneID" id="71980802"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00924"/>
    <dbReference type="OMA" id="PSAMISC"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="39420" checksum="7524DCC86162F864" modified="2023-09-13" version="1">MGRPKKRSRTEGPSTTASSTNGMHADASTEDQHTGLQSFDTATHYGSFESAWTPGGSLQPWLQSADDWNNDFAGNMGVPALTPDSSTHSPSLAMPPELGSQHSTGFGYGQMFGHHDTSTSMLVDPTLARNPVTISSTSNSGMPQYNMQSCACLSTMYLTLTSRQSMDTSFTFPFSLHPLREAMQAAATVLSCEECPMRCISAIQNTQLLGTLLMSIAERFSKLLDHISSESVRATLAGETKKFRLADLNTSISHLHAGGLGCQAAFSVNLSPEEWRSMCKKVVRAEVHGPSDVNDCCPYLLGLATQLEERQNRWHAGPPPEDFPHNMQARPVGQSVITPKEDRLCLKMVHYSQKLAEGLDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L961</accession>
    <name>A0A9Q8L961_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03557</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757480.1">
        <property type="nucleotide sequence ID" value="XM_047902705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L961"/>
    <dbReference type="GeneID" id="71983435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03557"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="408"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="50083" checksum="E239EAE8A021375B" modified="2023-09-13" version="1">MLSEDNIEKLRLQKRFAGPIYSISNAQRHEHLIDNNITRLLTRFKTMTDRPMDIYYAWEIMNVDMMTEFTFGQPYGAIEKGSDDDHMANMDRTVMEHSKAEDEGQQLRPCLHNDMHQLSRSNSEFILTWSFRLSITNLGAGVDTMSWTLAAVIVGIGMSPKANARVRAEMDAAIQAGSVIKGVPVSYNEAVKLPYLQACIHEALRLWPNVAISLPRIVPKAGIEIYGYYVPGGYTVGMQSKQLAIDDRIFAAEPESFRPERFLDADKAQLSDMTTRNLSFGGPSRKCPGKNVAWLSMSKVLASLWVDKKIFRNDADREQFIYAVLSVLSDNGRIKFNLTDYQFRLLFSRRPNGRFVATLVAMRGGIIEAKIEPSDDGKTQAEACRAFKKHVEERLHELLTTVPDVGAISSVSGPSSASRQSAVPSRNTPGQIQLRSGQDLPPAYAKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9C6</accession>
    <name>A0A9Q8L9C6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757563.1">
        <property type="nucleotide sequence ID" value="XM_047901541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9C6"/>
    <dbReference type="GeneID" id="71982271"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02393"/>
    <dbReference type="OMA" id="FYGFTFC"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="57798" checksum="E95FBC33E2E6082D" modified="2023-09-13" version="1">MRAPLNAERQHRTARILASIAATTIALSCGTNYGFSAWAPQFAERLQLTATQTNLIGNFGNIGMYAMGIPGGILIDSRGPRWGVAMGCVCLSLGYFPLKSAYDNGAGSMGVPMLCFFALMTGMGGCTAFSAAIKASASNWPSHRGTATAFPLSAFGLSAFFYTTLAAYLFPGDTSGYLKLLAYGTTAMTLFGMIFLRIVPTPGDGSGAYGVVPEDDERTAKRNDSIASTRLHRTSTKSTRGSHKRPGSKSRAPGEENSEASSLVSSDSEDGPGDFVDAMPEPKNPFHALHRSEITGWELARTPKFWQLFVMLALLCGVGLMTINNIGNNARSLWHHWDDSASREFIMKRQLTHVSILSFCSFLGRLASGIGSDWLIHNHASRFWTLVASASLFVAAQCVALNLEDPHHLYWLSGLTGVAYGMLFGVFPALVADAFGAKGLGINWGCMTWAPVVSGNIYNLAYGSNLDKHSVFKENPEGTGSERVCDDGRECYSSAYWITLVSSMVGVVWALWCIRSEKVEMLKAARGERRDREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9D3</accession>
    <name>A0A9Q8L9D3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cullin-4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02513</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757618.1">
        <property type="nucleotide sequence ID" value="XM_047901661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9D3"/>
    <dbReference type="GeneID" id="71982391"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02513"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000031">
        <property type="entry name" value="Ubiquitin ligase subunit CulD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="501"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="893" mass="100772" checksum="92485B744B91AF22" modified="2023-09-13" version="1">MKETPGVHSATSDQQTDRKRKRPSRQAVAGAEDTSSQQTLKSLFSTQQKPNHSCSPSSPSKKRLKADSTVPPLTPPGALARSEMYSFTSRSPVANGSTVVDLTNGSSPIAPRRMNKPGLNPHTGAKKLVVKNLKTNTSWDSKAYLEKIWRSLDEALTIIFKDGQSGFSKEDLYRGVQNVCNQGGASTLFSRLEGRCRSHVERDMRDPLLEKTGSDNVTILKAVIAEWAKWTQQMTTVRAIFFFMDRSYLLQSSKPTLEQFAPQPFRQAVFSNEGLKSKIVDGACDLVAADRTQTQALDQDLFQQTVDMLHALGTYTSSFESRFLGLSQQYIDEWSNTMIGEKSIPQYIALSEDLIAKEMKRCEDFQMDSSTRRDLLTLLEDHLVEQKETDLTEYEALKSLLDNNAMSDLTALYSLLDRRRLGGKLRPAFEKWVGEEGTSIVFGPEEDMVVRLLSLKRRLDLIWRTSFKRDEGLGHGLRESFETFINKTKKGEATWGTDNTKVGEMIAKYVDQLLRGGAKAIPEVLTARRSSSITAPPGQADAEDDNEDGDVDEDAEVNIQLDQVLDLFRFVHGKAVFEAFYKKDLARRLLMARSASADAERSMLTRLKTECGSGFTQNLEQMFKDVELAREEMQSYKQRLEDRVGYEKGKNVDLSVNILSAAAWPTYPDIPVNVPVNIKRAIDDFELHYKSKHTGRKLDWKHALAHCQMKATFSKGSKELVVSSFQAIVLLLFNGLGENDQLQYSHILAETGLPEPEVKRTLQSLACAKLRPLTKHPKGKDVNDTDTFSINPNFEHPKYRVKINQVQLKETKQENKETHMRVAEDRNFECQAAIVRILKGRKTISHQELVSEVIKATMSRGVLAVADIKKNIDRLIEKDYMEREEGNMYSYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9D5</accession>
    <name>A0A9Q8L9D5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Myb-like DNA-binding protein myb-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757485.1">
        <property type="nucleotide sequence ID" value="XM_047902058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9D5"/>
    <dbReference type="GeneID" id="71982788"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02910"/>
    <dbReference type="OMA" id="THHHSMP"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050891">
        <property type="term" value="P:multicellular organismal-level water homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901002">
        <property type="term" value="P:positive regulation of response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902584">
        <property type="term" value="P:positive regulation of response to water deprivation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902806">
        <property type="term" value="P:regulation of cell cycle G1/S phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032875">
        <property type="term" value="P:regulation of DNA endoreduplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000037">
        <property type="term" value="P:regulation of stomatal complex patterning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033993">
        <property type="term" value="P:response to lipid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000355">
        <property type="entry name" value="Transcription factor MYB124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="53"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="45942" checksum="21B77524CECA7A16" modified="2023-09-13" version="1">MPQHKRGPWSQQEDQLLIHLVSVHGAHNWVRISTSIQTRSPKQCRERFHQNLKPNLNHDPITPEEGIMIEQMVAEMGKRWAEIARRLRGRSDNAVKNWWNGGMNRRRRNQQARRAEFEVRQHHVQGHHHQIQNLPPPMHQQHQHQNQHQQQLPPSIQHQSFMQPQHYFAHPMYPGHGHPQHIQMPHNVAAFGRMMEAPLPSPSAFSQMSADGAPSLMSDCGSSMSARSPHHGPSPIELPPLAGARDERRRSSAPMLRLGVPGAFAQDTDFTTMQMPMHGYEEMRKQTPMLQEPFMPQPQSLPTPTAYLPSQPRQPSPLHQQHQMQQQYHMQQPQQVQRHHSAYPMPQIPSTPAKMELPGINQFSHEKPSITIDSRMATPIPSAPSPDDSPKDKMSLSNLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Y1</accession>
    <name>A0A9Q8L9Y1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757847.1">
        <property type="nucleotide sequence ID" value="XM_047902890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Y1"/>
    <dbReference type="GeneID" id="71983620"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03742"/>
    <dbReference type="OrthoDB" id="3650371at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="275" mass="31102" checksum="1DDCBF41C74C08A5" modified="2023-09-13" version="1">MDNSRLLSLPPELRNEIYRYVLVSDTRIIVSLGPTAEPPEISPKLKVKAKDALMPLADDLVHQEYDRSSIAARLALTSVCKQKRAESLPILLGENNFTMVIINGQYRPLIRMDTRLYFLLLRGWLSCLDGFAPCLKHITLDLGVRIEHRDPDAKPLLETLKGLKAVFRSFSCDSVVFTRIHLGQLPRGKDSRLHAQLGGSTKQKALDFLADAVEVVRDQLFERYANAEDDVLKKKGLSDPGALRKVEDNLFGWKAWVEAVLDKMDEDPLLRLKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAU7</accession>
    <name>A0A9Q8LAU7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758380.1">
        <property type="nucleotide sequence ID" value="XM_047902825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAU7"/>
    <dbReference type="GeneID" id="71983555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03677"/>
    <dbReference type="OMA" id="WHEENTL"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="52852" checksum="41284FAD96A81D2C" modified="2023-09-13" version="1">MSLVDLPVELLQKIIREHCNNKAIHALRLTCRDTCIAANELLLRQHPIYDHKTHIEQLAEIAEGRADIRKGVKRFTFLIDRLEPCNTFGGWNSARKRSFQHGADQTYHILRRIKANQPAPTDSELCKTLERWHEENTLIETWPKKMKTLAMDRYSRYRELVEYQAMLECNSNLRTRLSTFFAACPNLQHLHFSIKSSPQGRLLDRTFQSGLVIPKGDVDGGTFHFRETLLAAYDAKIIVKRLTINQLEHCITEDPEWMRVKEIHQVLQHVEDLHWSFAQCQLMDTEPYMIMDDFHEAFAAGRMREVLMHCPKLRKLDFCGPDADSGQEDENFPQLRHIVGEQYWDNLQDVSLSNIRSTAQEFASFLLRHAPTLQSIYLCDFHLTEGDWGVCLGMIAGKLPLLRKVVLERSLSSVEHGGADYWFDDSPSPDFPVDRLEPFVEWLIKGGQKSTVGSRGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB21</accession>
    <name>A0A9Q8LB21_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BD-FAE-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758485.1">
        <property type="nucleotide sequence ID" value="XM_047901695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB21"/>
    <dbReference type="GeneID" id="71982425"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02547"/>
    <dbReference type="OrthoDB" id="433474at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="61"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="35929" checksum="791D99517064E5E0" modified="2023-09-13" version="1">MDQLPSFGTSISDIIGPTLKTYEPLLLHNASQIHSLKKETHPYGPHSRQQLDLYHCPNPTIINGRRAILIFLYGGGLIHGSKTLPGYAQDLCHANIASFFAEKFGYSTVVPDYRLVNQHDAKFPSGGEDVAVAVEWVVKNAERFGKEPVDLFVMGNSAGGVHLSTLLLHPDFVATRAKVLDEGHVRLRGTILLSVPFHFRKALQNRQDVLETYFGDHESKSPLGLLRSAREAGGLDILQSKLRVFVLNGELDPEDEIMKPRDDFVEEWMKIGSAESRMALAVDFMRGQNHISPFCSLGTGIEREEAWGHQVGAFCTDIRRTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB25</accession>
    <name>A0A9Q8LB25_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758514.1">
        <property type="nucleotide sequence ID" value="XM_047902939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB25"/>
    <dbReference type="GeneID" id="71983669"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03791"/>
    <dbReference type="OrthoDB" id="3646703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="28787" checksum="F0121E074758759D" modified="2023-09-13" version="1">MASNNGAGGERAAEQTKGIFKGIGDATESLRKNVNAFADDMIGGKSNTHANTADRDREYTTGHVAGSGTTHDASTGVGASHPHDRPGGGPLSSHDTTGLTGNHSTTTTGPGSHFAGHGNTAGTTGTGLTDAHNTAATGTTNTANTASTGIHPDAQKTGAGIGAAVGRAGEKIEEKTSSGGVTHTSTGHGATYTRQAHEDEKLCPQQLKRVTKSTMQSRDRLLQDTPTYQINRDQMTDSLPFLSLFVNHSSYQAHRRNNLALTRPSKNDDRMFHDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBV4</accession>
    <name>A0A9Q8LBV4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758745.1">
        <property type="nucleotide sequence ID" value="XM_047903009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBV4"/>
    <dbReference type="GeneID" id="71983739"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03861"/>
    <dbReference type="OMA" id="YFERAPR"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="7"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1201" mass="137436" checksum="15FBE3301B928FFB" modified="2023-09-13" version="1">MARAAFDPFEALGLPRDASSQTIKSRYHALARKYHPNRHQGSDEAKATLAEHFHNVHQAWKLLSNVENRRRRTELLNLLELQDAMLTTFMDLLNAQSPDEPHPDQPQPVEHSEHDGNISSDADEDLPNVGLQRRQTFRNHGVKHLGDRRGSVDDNSPTSPTKKSLKWSISKAINARASAKQDQQKESDYFSQRRKKLEKLRRKELEAFFHYRDAMVAKFEAEEEVERHHAQYEQAKWKREYFERAPRGTTERFRSFQHFMGAVSAFGDHTPRRRNHSTLSYSTMSPIVGPGEGPQFLGPDHALARSKTMHHKRGWSSDISGDQTDSSDDEPSEINGTKHISPPIQWHQLAKRSQNTNRDYPRRSHHRTSSGLSEGDSPGPEFKVVVRQPSDLGRIEEANDSSNETLSNSSRSPSPHPDAMNSLQLYKFRMLPSSGTADLFGMPSEGRARSPSPVGRRRFPSMPEVPKAPRVSPSDGLKFETKLVGPPQYQHVHYDHVHQLSREEKSRILGAEPDTELDPAVLLERLSGLSTTVADKFEIKPNMEELFRFRLIYGTREVTRKQHQSFIALSYRRKIHVEKEKYHYTLPLDPEIYQAVWDERESDNEGVWIDQICIDQDSDFERTISMSAMDMVYRSARIVVVALDDIELEAHEGELLQSHMDEYESMKHVAARHRFRRKHPPYLESHDHMYKVIRKILRSSWFKRAWCRHEMRLAKHHVFLIPCKRPGTWSGRAVLRFNGKCIAHLLDLSIEVPFEPDVESVKPALHAFFRDRAKMATGEREMRLHHGNFSTVVAEVFAMEAGGDPRIPAERRLSDARKDKISIILNTMECGLTLRDALRNPSIHVTDNECYHLLSLLALAAQDPGALCCVGAPLPITDSTSSWLYTPTVADAGLNNFKTLDRLPENAHYVTSTSGPEHYIQLDLKFLPRDKAWTPSQDLDTLELARYFIATCDERKWGRNRKRYLTHDRKANLLFGSMHEVYVETLACIFHCGPNWMSDVCQRYSMSRWKVDLKGAYELLIALANTHGRWPVDAWSERAAGFIMDFVNFLTIRGLPQRQISKPEPWRPFVVASTGQVLGYAPIADEHIQLAIPTVLINPDYVHLARLWILAPRTTPSLTNGTTSSSATSIPIPTITLNDENISDWTLSGKSVLFSDEAWIGKMSTAQYRGDFQEQQKVYGRQLQRQHASNGVIRDRKLLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBY8</accession>
    <name>A0A9Q8LBY8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Endoplasmic reticulum oxidoreductin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_08043</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759057.1">
        <property type="nucleotide sequence ID" value="XM_047907191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBY8"/>
    <dbReference type="GeneID" id="71987921"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08043"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040356636" evidence="19">
        <location>
            <begin position="26"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="99"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="421"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO14691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="68683" checksum="8A750A0BB4B7EAD7" modified="2023-09-13" version="1">MLRSVAHAFHLAAFAILGGDCSVRAASATSSLTSPDVCALEPNATVSDACASYADLNTLNDKLEPYVRNLANNTDFFSYYRLNLYNKKCPFWNDENSMCGNRACAVITLDNEEEIPPVWRAEELSKLEGPKAQHPGKKQQKEQQRPLMGELGQNVGESCVVEYDDECDERDYCVPEDESASAKGDYVSLNDNPERFTGYSGEGAHQVWETIYRENCFSKPRSGENGASSPGISAVQPGLMNPLQGRAAQEFKSVVKAHDRDEAKKSGLPEDALEFEDECIEKRVFYRVISGMHASISTHLCYDYLNQTTGEWGPNLECYKERLHDHPERISNIYFNYALVLRAVGKLRDYVQDYTFCTGDSVQDARTKKMITVLADAIPAGSQIFDESVMFTDQTADGISLKEDFRNRFRNVSRIMDCVGCDKCRLWGKVQTNGFGTALKVLFEFGNGHAGEDKPLLRRTELVALINTLDKISAALKALEHFKLMVTAEIEGKPASSVKPVVPQSSDARDAPNFDDLDELDDFEDHKPPQLGEEQTIRELFWEELGLVFRAWKFVLRSWLELPRKIPVIVATEFERLFDFWLGKPMRPRSWELRFPTKEDLFPGRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBZ5</accession>
    <name>A0A9Q8LBZ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758942.1">
        <property type="nucleotide sequence ID" value="XM_047903041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBZ5"/>
    <dbReference type="GeneID" id="71983771"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03893"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF13">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32535" checksum="009ECE0136B71F40" modified="2023-09-13" version="1">MLNDQRRDSKESLPFIGTEEAETVDRYTSLGTGKRSLNSPKIALAAVTGLLLGLGTGLTLALLLQTHLRCQASTLCVCRQEETSPLLDDITIKYHEQTFNGSFVHRTIYRQDASPTVDAAWDALGVNFVGVLISREQASRHSIPQHWAHMPQEYGGQYVVNAQVHHHLHCLDLLRKGLYFNIDYYRSLGKGAFKNRPAVLKAHITHCLDSLRQLLMCNADVGVAGWIWVRNTPTSEPFLFPDFNSAVHQCRNFDEINDWAERNQIMYSPLGTVEFEPPRLGERIPVGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCS7</accession>
    <name>A0A9Q8LCS7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759370.1">
        <property type="nucleotide sequence ID" value="XM_047907886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCS7"/>
    <dbReference type="GeneID" id="71988616"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08738"/>
    <dbReference type="OMA" id="HARANPQ"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="162"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="413" mass="44567" checksum="B1419020CFCAD79E" modified="2023-09-13" version="1">MAILKELPGVTVTIVTGGRDLEEHTTADIMPTKRTFNCLVEASSDQIFKVQYRVRDPHVFEGSDLRFTVYVDGEETDGTLISKAEANSGTAARASRGLQVARDMMRRYKFTDVEIVGYASSSLPSATASMAPFGYRPGMLTPATNTSRGTTSASRSVVSATTHTPVSNMDELGTIKIEVTHVNRRRTEPFRVSGDHITNVDKKKKSARHSPVSHVISLCKPEKTRPVESVWVVDSIWGTPKPAATFVFHCRSSRLLHTMLKLNLSVIEEASEEPSYRGSDSVLVDNILGADALRGRGMHKTDQPGIPPNVLADRLQDLAISRLSEPLGTASVTSFSSSNGAARIFTPSSTTATNIGTYTPSSMTTTNVGIYTPAAQDDPDDSDSDIFSTPPETTRASSPAPTTPRQSTGLNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCU2</accession>
    <name>A0A9Q8LCU2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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            <begin position="403"/>
            <end position="419"/>
        </location>
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        <location>
            <begin position="422"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="545" mass="57514" checksum="00B08CC6533892C9" modified="2023-09-13" version="1">MATATRSSATASPHLNNAGIKSTTASPRSSRSALQTSDTLKKEPSVEAKPESSVPTINQPDETDATANNNKEAVTTNAPLAPPPKPTQNGGGDYFAGAHNDPNLSREPNPFESAFGNPAETPGKPQLPGVTSLTSPASLLPGNTPGWPGSLRSGPLSPAMLSGPSGSNDYFNSDHHFGGSFPTPNESSLRTGLTPGGGGSMFPQPSPNSQAIYNQLQSGGATPGTLDFHRTAMTARAQTQANTNTYGLGQGIATSQPQQNPNIQPDLDSKPYNPNGSTSNQDSQDPFGSHQTNDAANGLFMLAQAGGQQRNAQGYPMSQQQQQGYQQNAQMKQGGKGSVGSTMSGGSTGEDNQYSDDADSKPSTRNGRGRKGPTGKAANGKRKNDDPSAKGANKRQRGSTVSEEPEDADMGQDDDEDQMNADGKKMTDEEKRKNFLERNRVAALKCRQRKKQWLANLQQKVEIFSTENDALAATVTQLREEIVGLKTLLLAHKDCPVSQAQGISGMAMQQIAGDAHGFANPYGMAMGQGGPGMQQNMQQAQMQRR</sequence>
</entry>
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    <accession>A0A9Q8LE17</accession>
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    <organism evidence="2 3">
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        <name type="synonym">Cladosporium fulvum</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="34833" checksum="26D3279EB8557EA5" modified="2023-09-13" version="1">MDSDSIHNLAIVRGGLTVLAKESGSLRPGALLRELEKLRDLFKGIDIAEENAESARSSAATQVFNTYELTEMILQQLPLQDLVKAQQVCRMSRNVCRDSKRIGHGFSVYSVDVNLRCNAPFKKLIDFDLTRRLGLRNTLHLLGGQPVGPTANWLPHEWYAEPPDRAYVSFVLGHESKRTWHTRGFSRSDRFEASSTIYDRTIIAPATPTPNANDAERELWRSVAWTQDDCEVKVHLRRECSEGHPLDDIRVFTHGVTLGEIFDWMWSMITARPLWTKVKCPTGDLLDGHRTETQTNGTTVTYGPKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEF2</accession>
    <name>A0A9Q8LEF2_PASFU</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
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        <source>
            <dbReference type="EMBL" id="UJO16011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="372" mass="39977" checksum="E3E3512ECFFA06CA" modified="2023-09-13" version="1">MDRSRSPMAGAPGSGAGDMSRTSSVYSTDSGKKSTYLDYRNGHSSRPSTAYTPSFMSSTAMKSIETLATHSTQHQHQPSNPISTPQNGHHAIAPEPVKTDLGPPPGVLLVLATGPLRSTSIMSYLEMLLSRQRLSGIAFLADSAEELALKQLKMDVFGLIGRLGKELAVSVHTKDSWSRSQIEATIETVTNGGPGLQGVLCYPAWGASGGVLELEESDLAKTFRETVAFTHSAIRATADQLLAKSKPRDDTTNGVHRKQIGGPKGPFFLVSGPDRSLTGSGLAVAKLGCDAVLRELDITTRQQGLIVGYAEGVILPEPKRQVSKPKQELKLEPTEAYSQTQAREELSFVPGESPTKLWNMWALQNEIGSYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEG6</accession>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71985210"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
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            <begin position="100"/>
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        </location>
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            <begin position="103"/>
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            <begin position="130"/>
            <end position="143"/>
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            <begin position="168"/>
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            <end position="283"/>
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            <begin position="284"/>
            <end position="298"/>
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        <location>
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            <end position="316"/>
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            <begin position="505"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="UJO15995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="518" mass="57219" checksum="587107F21DFED85B" modified="2023-09-13" version="1">MPAPANGACVKWDDHPEMRVGFAVLHRELEMSSRNRVKVMNVAFEDQLEACGYPDGVPEDMFDTLESEWRERRKTQNAWKWRFTDAQRKAMEDKLKPIATSLGIDTTQQGNTASQATSNGRGVRAAASAGDDEEENREGEVDDAERQDTDNDDEFVERGRQSRRGRGRAATTSRGRATTGRTCDTNRTRSAATSRSTAAPENKKNPATKVKQPRQQKLRQSAMPLAQKFKKVGDPVPEPGFAPLESTTEYFNQPPVDSGWVLPGDDPRPLQDQEAEQRGREGGEYEEEDNEQDPEDIEGGAQSNPIPIDSDASDSNSSDDDEEPAPQNGRRAQGQPENGGFDDLEEDEEDDEYNFGEPAASGPYPRDHKRYVPPGKNKPSARPSKTTGKATSLKKGGEKNQKTSAYDNPYDNPHDKISDDEQEDGLFDPEDEGTPPRGKMSKSAAGKVETGKKKSQKNENTTQNKTKDAHHDDGLSFDDEPENEGTPPPVQKTQPAPGKESGSGKKGRWGKKRPSNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEH1</accession>
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        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="1" type="ORF">CLAFUR5_04637</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903785.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LEH1"/>
    <dbReference type="GeneID" id="71984515"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04637"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="61047" checksum="7DE74C772BA8F300" modified="2023-09-13" version="1">MENTNTQNRTKRVSIFKSHHATQILYPSRLLLKDGEAMSISYPGDAQDRFERHPVVPDAAVILNKTSGNHDLDTDFTTYNPTSLWYDDDTMSTGDLFKDMQAVTQHVGATKLRVVLYYEPAATAPGAPRKNYVRINRFTRFEFPDRKPFYDKVEYEIPYRDLPRRPTTPWEQDLFELVRMASARAVLHAQQRLAAVGGRLPEYQWKAPRTVALEKAIAHLATVMTKAELSEYNSTLPDENDHIKECPFCTEEFDDADTTDPVKLRCSKRHVLCKSCVQNICRTSGIANVRWPWCAVLLANDPNNHILKPNYLDPAAPFRNDPRYTKHENFERGCADLDAGHVRDDTTKIVISKARFDFVCEILIHTSPSPERHERYWRDHRYTAEYTIVTAAVHAFCRGWNGESWPVNEVYKQMRHMIFHCLADEWKKGEMYAYATDKLKQDVGEDLSKVPLRPGFVEFIDRSLNRLLRFMVVRRCDRDCGTLCGFHAHGERSFHKVYWATREDDVFGCIEDVLRKKRKARTWAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEZ9</accession>
    <name>A0A9Q8LEZ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760554.1">
        <property type="nucleotide sequence ID" value="XM_047903982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEZ9"/>
    <dbReference type="GeneID" id="71984712"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04834"/>
    <dbReference type="OrthoDB" id="5431013at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16675" checksum="EAEFCDC14FFF8B97" modified="2023-09-13" version="1">MAEPFSALTGALQVADSGASLCSTLYKHAQDVKSVKGDIYALTEDIKLVESPLKQTAEFLELEAASTIFDDEGRAVAYRAVDQCRNIFIQIRDTIQAYYKTDANGQTVFSTLEQFRHPFEADRLLALRQRLEWPKNTLREESRKQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGF8</accession>
    <name>A0A9Q8LGF8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05278</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761327.1">
        <property type="nucleotide sequence ID" value="XM_047904426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGF8"/>
    <dbReference type="GeneID" id="71985156"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05278"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="227"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="30312" checksum="22F7B1DFA4D5D72D" modified="2023-09-13" version="1">MDNIQHDRVTANMVQHPNMPPRSDMPAGHIESLILSLQHANPAPPTAQNGAPVVGSGGMIVHELVSAPRYETDGNMVVPPLPRLLGFPLATQSAGSVLHPVDGLYNPHAHLFFLEGDVNKDGFGTFTSPPVIGNIVVERCDGKDLKGQQLCSLISFINNHIVGDLQELSTVDEEEKKRIVAHPTNTIKPHAFYEYFERHRGVEGFEQWEGIENPVQLTEEEKKKPICGACFATEQKDGKPLLKCGTCGKVAYCCRDCQVFDWKDGGHKKVCKKAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH10</accession>
    <name>A0A9Q8LH10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760844.1">
        <property type="nucleotide sequence ID" value="XM_047903776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH10"/>
    <dbReference type="GeneID" id="71984506"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04628"/>
    <dbReference type="OrthoDB" id="5309037at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="748" mass="81396" checksum="1B445CAEE28097FF" modified="2023-09-13" version="1">MADQVVKPANMNYSNMIEEKNLKKGFIVATLISTIVGTFTASMTLHDKIAERRDKKKQQGIDGGQNTEIKQLKEQVAALKVGEAPKDEKAAGGEKAGEDKKSASADDKKSQAAGDGKKSEANVDAKKSQAGGGEGKSQVGGEKKSQAPNDAKSQHPRSRSSSKSSKGRRRRRDSLDADQDFARVANQSKNVIEQTFKDNVQRLGPEYAEGDLTTVNALQSQILEQQKTVIGILQTAVSEGRELTEDDKRRLIAAQNAATNGSLDALQGQYERMAAEKDAPPAPKSVAPPKSFVPPIVAPPTVAKTAVPPPGTAVNKPWESDPLPPPTEDRRRSSNYGRNAAIAGGLAAAAGAGAYAANRDGKREADRAYSDDGPPRRRPAPEDRRRSSLRPSEQPLPPAHDERPRRQEYSPPRWDDGRSSTKPRDRQRSSGDDRRSMMTRRGGQRDYVDDRRSSFRPRDQDCDFVPRKPSSDPMTARNRPPDDRRPSMKPQDPGPPPARPKSVAPNTAAPTAKATTIPAADPSNQAKSIAPKTPAPTAKATTIPPAKPPGGTVKETAAKQQDEAIRPSAIESPPRSSNHSSQRSKHSVRGSPPPPKSKMKALPAPDAPLFCRYAQDLQRHGLPLHKTFKPGGPHCCPSCNLIIPVDTRDIWVFSTHIPPQQKGDKPRTRDYRMDSRFVVKCHDGQGRFACVLCDKNRDLDCICKNVESLIKHLGSAHTFEEFDQDPDLVKMKNGSVVEMKGGKELVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH29</accession>
    <name>A0A9Q8LH29_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Carbamoyl phosphate synthase arginine-specific small chain</fullName>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Arginine-specific carbamoyl phosphate synthetase, glutamine chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_06107</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761726.1">
        <property type="nucleotide sequence ID" value="XM_047905255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH29"/>
    <dbReference type="GeneID" id="71985985"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06107"/>
    <dbReference type="OMA" id="CFSVQYH"/>
    <dbReference type="OrthoDB" id="434at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000003">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF7">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="17">
        <location>
            <begin position="52"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO17360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="49493" checksum="253D65791F03725E" modified="2023-09-13" version="1">MASTLLRSFKPSGLKNNLRPLYQARYNATVAPGTPRVSTPPTSKRSTKPSYERATFTIRDGPVHHGKSFGARTNISGEAVFTTSLVGYPESMTDPSYRGQILVFTQPLIGNYGVPSAERDEYGLLKYFESPNIQAAGIVVADVALKYSHWTAVESLAEWCAREGVPAITGVDTRAIVTYLREQGSSLGKISVGEEYDADEDEAYEDPGSINLVAKVSTKAPFHVPSPNGNAHVALIDCGVKENIIRSLVGRGASVTCLPWDYPIHKSANHFDGVFISNGPGDPTHCKATSDNLRELINSSQIPIMGICLGHQLLAMAAGASTTKMKYGNRAHNIPALDLNTGKCHITSQNHGYAVDPTTLPSDYTEYFTNLNDGTNEGMIHKTRPIFSTQFHPEAKGGPLDSSYLFDAYLQSVQQYKQNQDVLKGGRDNRPSPLLVDLLAKERVGVAPGVAGVPGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH62</accession>
    <name>A0A9Q8LH62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761771.1">
        <property type="nucleotide sequence ID" value="XM_047905384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH62"/>
    <dbReference type="GeneID" id="71986114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06236"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="370" mass="41733" checksum="26DAE19498D9FC8E" modified="2023-09-13" version="1">MDRSELLAKWRGLQSIIYQLSYTTPYDDLISGEAEMLSQAVTTSVGYTGPVLHSNAMWNTIEIQELVGQMQRDGRRKLAALEALYHDSFDYMIPSDRGEPDEPESLASSDIAMDLIYSNIGRAAEHTRLINEALSNRVNTAQHTKLKRAVEGLEGRMNSFETWLENMGSAKTARVSFEAVKARFQAEREQNHQVDQTRPVAPAHPAKPIKPAKPAKPTKPPKPTKPTKPPRPIKPARPVKQAPAMDDTVMSEDVGEATPEPMTRRSDRNRKPSRKQQEMSATENDEEIARVEQEQEFNEKTPSPPRTTKPTEPTESPPQPAYLTQRMAEHDRGELQLTDPAIPMGSDAMDMDDEIDDKFMHEDQEEDDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN0</accession>
    <name>A0A9Q8LHN0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762026.1">
        <property type="nucleotide sequence ID" value="XM_047905661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN0"/>
    <dbReference type="GeneID" id="71986391"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06513"/>
    <dbReference type="OMA" id="AEVKLMY"/>
    <dbReference type="OrthoDB" id="542841at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009066">
        <property type="term" value="P:aspartate family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.40:FF:000001">
        <property type="entry name" value="L-asparaginase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00057">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="4">
        <location>
            <begin position="38"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="5">
        <location>
            <begin position="279"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="48416" checksum="E9AD6C314601F992" modified="2023-09-13" version="1">MSSGIYRLLHFVSTNRERYQNNKGMADGDKTPPYEPSILLIVAGGTICMQDSEDGLVTSKLFLDEVLSPRPMFNDGTPVPVQKIIDEHGIERDAPSLRLPRDRNGANVRCTVLEFNPLLDSSTAHSPTWNQLTRTIRSNEDNYDAFVICHGTDTLSYTSAALSFMLMPNLEKTVVLTGAQRSMFFADSDGSDNLLGSIVLASHLRIPEVCVYFGHKLLRGTRITKISASSYSGFESPNAGPLATVSETGITVHYDNLLHPDEEHLKKTTKTFNEIDSSKVLVLKVWPGITADVVECMLSPSHIRGAVLETFGAGNIPFDVIPALKSAVQRGVVIVNVTQCLHGSVSDAYEPARKLVEAGINLGYDMTTEAAYTKLVYLLAQGHTSAEVAAKVSTNIRGELTPPQAADVRKGPLSIAELPIRYERTVPGRLSVDYGTTHGSIGNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI25</accession>
    <name>A0A9Q8LI25_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_06423</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762136.1">
        <property type="nucleotide sequence ID" value="XM_047905571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI25"/>
    <dbReference type="GeneID" id="71986301"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06423"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO17770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="393" mass="40852" checksum="FAC3A7991663251B" modified="2023-09-13" version="1">MESAMRMRMMRIFTRGANKLTKDFIQYQFLELVTASSSPRPQHRTMAPLSFISFCGLALSTTSVFANPLPLPEGSTDSGCTFSGSDGASKAQQSKSSCSTITPSSVEVPAGKTLDLTELNDGTKVVFQGTTTFGYKEWEGPLVSISGKKITVTGESGSLLDGDGSRWWDGEGDDGKTTPKLFEAHDSTSSKISGITIKNSPVQVFSINEVEDLTVEGVTIDNKDGDSQGAANTDAFDVGSSTGVTISGAKVYNQDDCLAINSGKDITFTGGYCSGSHGLSIGSVGIRIKTIVGGKGAVKGVTFSGIKLSGITDAGIIFEQDYKDGDNTGHPDGDVPITGLTVKDITGTVSDDARRIHILCADGACSDWSFSGVSVIGGKKSSKCSGVPSGASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIM2</accession>
    <name>A0A9Q8LIM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762436.1">
        <property type="nucleotide sequence ID" value="XM_047905376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIM2"/>
    <dbReference type="GeneID" id="71986106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06228"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="36771" checksum="B204FCB03F356B80" modified="2023-09-13" version="1">MRDRKHDIQLPGMKRFTSYTEYYDACRKVCEEWTAKTAIGIDLNFFRTLADRPVKEETNEELHDTDDDVAVGEQELLAPTSVKKQELKVTRSRSAPVDNTVQAATPKQFLYYLYHSAHRLIVDDMYGAFDQGSFVHRKLFRRSLPGGVPAFLEISTAWRCLMLASYLIWIAGSKTDCSPADQMDDDTEHALAYPDLPCYIDYADKDDAFYDVMYGLWLRGLVSESRRWFNESRIRRMVGYIGSEEEFKAHKALEGWCEKLTAKAGLPKRDKDDKAVLWGNIWMKALEKWLRDYAGAKMYGTFADCLKEVALAMIGALDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ20</accession>
    <name>A0A9Q8LJ20_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762661.1">
        <property type="nucleotide sequence ID" value="XM_047904617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ20"/>
    <dbReference type="GeneID" id="71985347"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05469"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="237" mass="27084" checksum="93E6B1AC2D37547C" modified="2023-09-13" version="1">MVYHMPECRDFSSFLLSAELSDVTIQYEDGLLPVHKIILAQASEYFKTLLTGPFAEAGQRIVELIDDPPMAIEGMIAWIYGMQFNPRDRYNKYIENFHFVTSDETGVEFVKYQVDLFFTAEKYLLSRLATSVEGYFFHMLLDVSRQVEFLHVIAKHVYIARAEEAVALRVHVANAYLERIRSIKDTEELKQLLLDIPELAFDIIRAGATLPAAEEEDDKPRKVSSGSGAFPPLPRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ62</accession>
    <name>A0A9Q8LJ62_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762737.1">
        <property type="nucleotide sequence ID" value="XM_047905451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ62"/>
    <dbReference type="GeneID" id="71986181"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06303"/>
    <dbReference type="OMA" id="SIWDYSK"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="222"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="54389" checksum="109708070A052E3B" modified="2023-09-13" version="1">MADQDMHDHHQHREDDDAMLDPNEAEEVIDQDDDAAMDSGDDEDNQIMQEIQLRNDSSAHFDHHKKSIFCIAQHPTRPEIVATGAGDDIAYVWDSTPPEGPVLPASYETDPQPRERKGQEILAKLEEQDESVNAICFTLPKGEYIATATLAGKLNVYTTPTDSKPAKLIGSAKEVDSVNWMLACPHKDYPNTIALGADDGSVWIYTVNASDPSSPLTIVQSFFLHQAPCTAGAWTPDGKLLATVAEDSSLFVWDPFGDAAAAGVTDPNGSQAVFGLSAADERFKVDGGLYSVAITMGGSLVAVGGAEGNIRIVGLPRLGAQPANSTAGAKGAGARAKAGGAKQSGTPGAANSANAGGASAGQAGQILASLQAQSDGVETLDFSQPPLQYLAAGSVDGSIAVFDVAHSFAVRRHIKEAHANEEVPQAVTKVQFVKTALGTQNDRNWLLTSAGNDGVLRRWDVRGGTAAAGQGLAGEWRGHTGDQPDENGENGGGILDFVQGGGGKRVITAGDDGVALVFDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJD3</accession>
    <name>A0A9Q8LJD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762849.1">
        <property type="nucleotide sequence ID" value="XM_047906314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJD3"/>
    <dbReference type="GeneID" id="71987044"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07166"/>
    <dbReference type="OMA" id="YRTNKHH"/>
    <dbReference type="OrthoDB" id="1166329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12480" checksum="233D5C1D13E5835C" modified="2023-09-13" version="1">MSSADAKGHRLYVKGKHLSYQRGKRNTNPNTSLIKIEGVDEPKGASFYLGKRIAYVYRGKKEIRGTKIRVIWGKVTRTHGNSGLVRAQFRNNLPAKSFGAMVRIMLYPSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2G9</accession>
    <name>A0A9Q8P2G9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="6">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01849</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755120.1">
        <property type="nucleotide sequence ID" value="XM_047900997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2G9"/>
    <dbReference type="GeneID" id="71981727"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01849"/>
    <dbReference type="OMA" id="RKFPKCY"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="372" mass="43567" checksum="9F410AF3B3421CC0" modified="2023-09-13" version="1">MASHGVPRVSGASVDKSEQARENERKQIEHYKSLERQVTEKIKAADYSSTALQLTSSLLSQNPEYYTTWNHRRVILADVFARDLNNTDAHVEAKDAEAAEKAGLTIPQREILLLIKEDLQFLIPLLRQYPKCYWIWNHRRWLLTSAATYIPPRAALELWQGELGLVSKMLSLDSRNFHGWGYRREVVEQIERLREKSMVEPEFEYTAKMIRSNLSNFSAWHNRGQLMPRLLDERTADVEDRKKLLDAEFELITEALYTDPYDQSLWFYHQFLMSTFDERNPKAPKILANVGNAERLEYLEQEIDSVREMLDGAEDCKYIYQALLEYSSRYLEVDAGNKKVTTVEMKSWLDELRKIDPLRDGRWGDLARKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2N2</accession>
    <name>A0A9Q8P2N2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755213.1">
        <property type="nucleotide sequence ID" value="XM_047899404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2N2"/>
    <dbReference type="GeneID" id="71980134"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00256"/>
    <dbReference type="OMA" id="MNPVEWI"/>
    <dbReference type="OrthoDB" id="5403181at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="2">
        <location>
            <begin position="120"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="694" mass="77533" checksum="3E9C35A304ABE6A8" modified="2023-09-13" version="1">MAELNDALTHLGPVDWNDVPQDNLEQYLTDTFAAGELICNSVPQVPEGTPFHDSKPHHHEPNTAKSHKEMHSSHARGHPPHEEHAKLAKQWGKPMKFKKETNPLDVSLYKMAGHDRHGAWFARRSVHEGLGFDKFKRAMLREFPQSLSVEGGPGAGAIRGLAADRRLERIDVKGVGKLEVYQLSSVFPGPVTPRDFVTLLLSSDGVLTDKSAAELEGGKRHVPRHFMLISKPVQHPDAPARSGLVRGQYESVELIREVPLAPSKSKSTPNLLSSNGTSEQHTRERGHTVGTANVKGASASDQHLDVPGSSGEGDPELNPVEWIMITRSDPGGGLPRFLVERGTPEPMIQDVHKFFDWACSLDHRPHPDEGFEEQEKESISNAHTTDQVSTQTTSYTPNGDNQEESKLAPPIRSATGPVPRPNSQGGIFNNITRAIGTGIDTYAPAAVAVADRVSPYLNSGEVDSSDDSSDTSSVDSFMSAEEMRRISTAPEEPKRPTDSTDVLSIASADLSDLPKDTKDMSHHEKEVYKITQKRERLEQQLARKRMEQEQKLKQTQEKGESESSKQKEEMEKKLKKTEEKHKRELEKLEQKKAKELRKVEDKRKKKDEQHKLSLVTRERDEFRSQVDLYRRENSLLQEQVADLQKQNTLMAQKLQPEALQSVKEEFGRNRKGSMRSTNSAASSRSNERKIDAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2S3</accession>
    <name>A0A9Q8P2S3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein sym1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01298</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755420.1">
        <property type="nucleotide sequence ID" value="XM_047900446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2S3"/>
    <dbReference type="GeneID" id="71981176"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01298"/>
    <dbReference type="OMA" id="WYQSKLA"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20747" checksum="9119C49FAA4C4FBD" modified="2023-09-13" version="1">MLRWYQVKLASSPLLTQSITTAVLFATGDTMAQQLVEKKGIANNEWARAGRMALYGGCVFGPAATKWFGFLQRRINIPNRPNATIVARVLTDQTVFASTNLFCFLSSMALMEGTDPKEKLKQSYGTALQKNWMVWPIVQATNFKFVPLEHRVLVVNVVSLGWNCYLSYLNSAPSGTHDKDGGELPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2T9</accession>
    <name>A0A9Q8P2T9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4-hydroxy-2-oxoglutarate aldolase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755661.1">
        <property type="nucleotide sequence ID" value="XM_047901182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2T9"/>
    <dbReference type="GeneID" id="71981912"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02034"/>
    <dbReference type="OMA" id="YNFPVVC"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF47">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="33840" checksum="5EF38FD5355E73E5" modified="2023-09-13" version="1">MNGSTHSNVPPAGIWAPAVTFYDNDELDLTSQAKYYKYMSKHLTGLVILGTNAETFMLTRDERAALLKTAREAVGDGYPIMAGVGGHSTKQVLEFISDASAAGANYALVLPCAYFGKQTTPKVINTFYSEVAEKSPLPIVIYNFPAVCNGIDIDSDVMVDLAKKYPGKIVGTKLTCASVGKITRLASTFESSEFATYGGQSDFLIGGLAVGSAGCIAAFANIFPKTVRHIYELYKQGKHEEALKLHGIAANAESFSKAGIANTKFAVSVTTARSAGIEDAEAKLVPRRPYEPPTDAVKKDIRAKMEEMIKIEDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P323</accession>
    <name>A0A9Q8P323_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">Bud22 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P323"/>
    <dbReference type="GeneID" id="71980587"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00709"/>
    <dbReference type="OMA" id="ALWEKKF"/>
    <dbReference type="OrthoDB" id="3364872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037393">
        <property type="entry name" value="Bud22/SRFB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015158">
        <property type="entry name" value="Bud22_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325:SF1">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="33"/>
            <end position="448"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="49099" checksum="F5C04599FD07DCAE" modified="2023-09-13" version="1">MSKRKRGSDAEEEDTLPAATDFRRQRQIAATFEDSAKQLARAFKAGKGFERQKLGRRKKHAAAAKDDKDVERIDAEVAALKILDNTLAAEHHLAKSLLKIKAIATSPNLPPDLQRPKPLPTDAPSLNVNARLCNSNPVKEAFPTAVAAVKREFGIKDDPKAPNKKRRLRAKDYDTAGRARSMSVSSADDEGDNGAPLRKRRAAEVSDDDSEPQDGSEGSEDDLQQYRGRLASSSDEEGDDDGLDGVSDIEELERRLMAEGISRKAGKRKTDKYDHAADLSLSEPSDDESVEEQPRKAAAPKKSSFIPSLTMGGYISGSGSDLDSDVDIAPKKNRRGQRARQKIWEQKYGSRATHLQNEQRNQGWDPKRGAVDSDRGGRFGKNKGNGANSMALGKDRRNPGQTKPAAEVKTKPRKDDSGPLHPSWEAAKRAKEKKSAPVAFQGKKISFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P369</accession>
    <name>A0A9Q8P369_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Luciferase domain-containing protein</fullName>
        </recommendedName>
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    <organism evidence="2 3">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P369"/>
    <dbReference type="GeneID" id="71981096"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01218"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF17648">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="160"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="28236" checksum="D6EF259BC947B725" modified="2023-09-13" version="1">MLHSYASSMATVVAQLLGAMLVIAGLLQAAVCLKSDYEAFIDLGPGGTPQTVYGYLKVKCLGLFALRNRFLAAPIPNDFITKQGYLQSLPPRDRPRPVTRGIAPHRQIDQKLDEHTYKKLARAVEAMAPGKNNDMVIGTSCFEKHGTGLFSTVPANTTCRGEIVHLHPSDGSFHMTLHPADANTMLQAGWGERHPLAGVFFKRFLPVGFCMVYAPQSDEEIETVLEIVRAAAWYVSAGRSGCTLMEKKPVHEEVTRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P387</accession>
    <name>A0A9Q8P387_PASFU</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71981269"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01391"/>
    <dbReference type="OrthoDB" id="3938057at2759"/>
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    </dbReference>
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            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="23421" checksum="B810C316FEAF0760" modified="2023-09-13" version="1">MVGNFRCFSMHSHKLTSPMAFDWRLAKLTRRQRTAIYICHFPQLLFLFSHHNYQHTTNNIPKTVTAPPVLQHPHYKITIQAPNMADKQANQTFSFEIVSCLLAALSESGATVGAKHYAMMAKIDGTKSQSGYEHMFRAVKARAKEINQQNANGGGENGTPVKKTKSAASTPASKRKRGKKAAGEDEGDDAELDTKKTKVKEEKNDDSGDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3N2</accession>
    <name>A0A9Q8P3N2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isoaspartyl peptidase/L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00991</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756350.1">
        <property type="nucleotide sequence ID" value="XM_047900139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3N2"/>
    <dbReference type="GeneID" id="71980869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00991"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </evidence>
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</entry>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8P584_PASFU</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="4" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
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        <property type="protein sequence ID" value="UJO13621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_02894"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
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        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="20438" checksum="7FCF6314E74C76D3" modified="2023-09-13" version="1" fragment="single">ENEGSCDGLNFSFDDRILDTTNTTQQSRYERILGSEHSGRRILISIVKMVAAKPHVPIVKKRTARFNRHQSDRFMRVDPSWRKPKGIDNRVRRRFSGQAAMPKIGYGSNRKTRHMMPSGHKAFLVNNTRDLELLLMHNRTYAAEIAHAVSSRKRIEIVARAKQLGVKVTNGKAKITTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5E5</accession>
    <name>A0A9Q8P5E5_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_03174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758210.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5E5"/>
    <dbReference type="GeneID" id="71983052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03174"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="25570" checksum="D6648178CBE2A8A2" modified="2023-09-13" version="1">MPFKRCEALLWLRSQSSTDVLQKQAVLPQDMTIAAVPALVSRLFCTSTPTLCPLHRPADRACLPNNGTAADWTRYEQAGLALNSALVHSSEPKYLTVVKQTVRQAYHNSASDLLANVPVATKHSSHPQRRMAYHRYPTYVVDEITRDRYGVDVPTLLKDNERLRASIHHRDRELDRRDREVKEYKLAYVRLKDKYITSQQRHEELKARFRELMARRWGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P633</accession>
    <name>A0A9Q8P633_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-oxoglutarate-Fe(II) type oxidoreductase ppzD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758768.1">
        <property type="nucleotide sequence ID" value="XM_047903030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P633"/>
    <dbReference type="GeneID" id="71983760"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03882"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="70"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="24990" checksum="7AC39C078D1C952E" modified="2023-09-13" version="1">MDARDAGEESFEIGRETETETETEAELSNQWPDKFDEEGRVFKARMLEFHELGKWLRGRIMRAVAVGLGIEEGWFDRLLHYPEVRSEAFRENGNTVRAGAHTDYWSITCLFQDDRGGLQVLPPSSNYVDATPIKDTIVVNAGDLLARWSNKTIKSTKHRVVEPPTTADVHPARYSIAYFCNPNFDQFIDAIAGTYSETRPKQYPGMSSGEYLVQRLAATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6B8</accession>
    <name>A0A9Q8P6B8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759200.1">
        <property type="nucleotide sequence ID" value="XM_047907526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6B8"/>
    <dbReference type="GeneID" id="71988256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08378"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="242" mass="27148" checksum="A577367773578484" modified="2023-09-13" version="1">MCQVKTFQYDMCGHFYAKILSACKGTITHTTRAGITKPSCNPTKSLREKKDAPVIHYPGRCLHCQMEALRAHGQAQVDVLKEQSEASPVKKLKRRAREAELQHERTCATLDSLKIEVPVAKRDIVLPSPQMRQRVIVGSPLQNEVTYGAPDIDEAMPNEEAKPTKINSPRRLQQSSLRSRRACRTYLGQCITQDCRHCKKPKRAVQDTVVAKEVVMPHVGGGMNLTAHERRTLPIAVSFDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7C3</accession>
    <name>A0A9Q8P7C3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO15871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903693.1"/>
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    <dbReference type="GeneID" id="71984423"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04545"/>
    <dbReference type="OrthoDB" id="5355510at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
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        <location>
            <begin position="292"/>
            <end position="532"/>
        </location>
    </feature>
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        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
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        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
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        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
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        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
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        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
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        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="532" mass="57332" checksum="0102DB27EB92709D" modified="2023-09-13" version="1">MSTYNTYTQQPNFMPGMPSAPSVVTAAPGQSRLTYFIARNNGLPVPLIPADELPFSVKLQNVPRVLTPAQAYGLHYCGSAPYSGTTFQVEVDAATSTCMQRSTSQPQNEPSYIRSQANTNTKHFLAPDALARQALNNSTAISSVPSVVTVPKRPVSASETAMSWRRSDPVKPAPAITTSTDATQSVIDAILRSETGAEAAERIGYYPKDSTPPPSGVIPDQEKKEYCTYWILHGDCMYVQQGCRYKHEMPSKEKLHQIGIRHVPRWWQEQNAAIRMVGEKAIVGPLKKPEEWLNMRKGSDTSSETSTATAESKAASGTSVEEELATKQEKPAVPKSKSRSTSPVVPPTRPSSPMDTGKERKPSCDVDLIDFAPLLPTPSSAKAPTPSSTQTTKRSVTISEPSIIKTPELATARTIKSPDSPPKTTKVFVPAGESPEAHIADAKKRERMAAGKASRTPSPSKNVKPGDVKILAKQSSEAKVEGLAASKWASKVDEGATAKETPKRGKSGCRIRRPASSSPAARKKTEAIGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7U9</accession>
    <name>A0A9Q8P7U9_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904351.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71985081"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="527"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="704" mass="80276" checksum="1994C006C964CF83" modified="2023-09-13" version="1">MIGDNAGALGTLDVEMSHIRYQVGYAMAERTFATQEEIYVFLRCVSDALSKYAAATGHIKWRDASSKGFLEDGSVLPPQILRLWHSAPSPHVLDPKNIMDIARERFTAAENELEMLQTQPEYAERRIESLSGSKEFALETASGKWLTLCRRLWQHQVYRAQSWDAITIKAKTLANTLKSLEDTWDRRPDSTPPEIYLAAAEALKDATLWALIEAEKELIKLIQRQKRFERHNMYKRATATTHVDITTKHFTKLGTVKVEPLTRSDFEADPLLWTLTWASGMPENDNRLYPLDSVAYATYLLDHENEHDRVDASFTGLIDVIGDLAAIQDILQGFDASRPCAWVAPADEKKRLELRKLLQVSGMLSHNESRITGQFRNLYEDCVADIEKNTSYDRLDMTDAKLSPAAVRLQAFCEKAPWPRGVTDGEERLQEQSIAHRALREFWQALRQARLEQMRTNNKKKTPASRVSPEGIDGCLEARLLSKFKGDAYLEQIQDEIRELSQDKARTLMRRKLRAEAAVNAKAVLAPRTEGAATSPKNTRIDKKKRKRDNKKDRTQQQDAALALIREMAPRWFEDEEDNNDVDEPAIEDEILEEPVSPGDRIPINRASQAVLGRIFRKDQTAFRWQDFVAAMYDAGYSVTSVAGSHHKFVKAEGKGKGSIIVPRPHNHAAAMEDWNIRPLKTRLTVDVHLRYQSFELRGKRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K2</accession>
    <name>A0A9Q8P9K2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762397.1">
        <property type="nucleotide sequence ID" value="XM_047905597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K2"/>
    <dbReference type="GeneID" id="71986327"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06449"/>
    <dbReference type="OrthoDB" id="3650964at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="260" mass="29061" checksum="83D07CA998E2946A" modified="2023-09-13" version="1">MATTTSRDPASPPPDGTCHFYTLPRELRDYIYQLAFTATRAAFKPAVEKAFTRPIYHTVNKQWSAEATPIFLRRIDALFGSPELFEECITSSHMRDNLKNIILAMPCSSSNCDSSCGSPHSKNGEGGLPKYDDRMAAGLAGLASSVHECPRLETITIQIGINWVDSLLNWTKSGSRKPTSAEPSSRFVQQLVHELEKLRGLQVMIALPPHDIRRRVQDHVISLAQTAAHFRPITTQPRTNDHVSIGSRIKRTSTKRRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9L9</accession>
    <name>A0A9Q8P9L9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Quinate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06412</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762664.1">
        <property type="nucleotide sequence ID" value="XM_047905560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9L9"/>
    <dbReference type="GeneID" id="71986290"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06412"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF81">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="340"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="383" mass="42336" checksum="28E817279A05E1A0" modified="2023-09-13" version="1">MLSFFVNYGVNTSISSTSSTQWRVPFALQMVPGALLLAGIFFQNESPRWLVEKNRIEAARQALAQVRAKDIHHPDVTRELEEIVEDFNGQEKLPLVAQLKVTCSSSKTFYTFGMAVTLMFWQQWTGTNSINYYAPQIFQSVGLGGNSSKLFATGIYGVVKVVITALGLMFATEQVGRKWSLIIGGCGQAFAMFYIGINQAVNPVTPGAALNGNSTFAIVCVYLFVVFYSFGWGPIPFVLSAECAPNHVRSLIMAAALMTQWLMNFVIAKLTPIMLAKITFGTFLLFGACCIIMVVYTVFCVPETKNVPLESIYLLFEGNIIKGATKDTIPRFSRAKVLQHRRNGDSEEAGVKDVDADSAKHVERTTHEELGSNVWYPQNGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9W5</accession>
    <name>A0A9Q8P9W5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_07500</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762939.1">
        <property type="nucleotide sequence ID" value="XM_047906648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9W5"/>
    <dbReference type="GeneID" id="71987378"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07500"/>
    <dbReference type="OMA" id="RCQEIDY"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="366"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="583"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="249"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="827"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO18573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="847" mass="95820" checksum="EAF43C129621684C" modified="2023-09-13" version="1">MAPKRKGSTAPSARPSKRVASGVNTPQSMSDDDYDSEGDVSDEMMSEGDKKAPKKYDTVVKKFQPQSYVAHSGPDAASTLFKPGRDFSTEQLKPDHHMRPLWIDPANGRVVLETFAPLFKRAQDFLINIAEPQSRTTNMHEYTINPHSLFAAVSVGLTEQDIIQELDTFSKTTIPENIIKFVSEVTQSFGKIRLVLKHNKYFVESSDPSVLQMLLRDPEIARCRVEDTDELQTDKAAKRGNMLIQGTAEAARMKEAEAQEQARLAQKREEDDDESDDEFGGREADKDMAAYLREEEEEEDDVDVVHSFEVRGDMIQKVQEHCNVTLGLPLTEEYDFHADERNAKLDIKLRPVVQIRYYQEQALAKMFGNGRARSGIIVLPCGAGKTLVGITAACTIAKSAIVLCTSAMSAVQWKEEFKKWSNIDPDDIAIFTSGEKQQLHHKAGVIICTYSMVTQNARRAHDSAKVMDFITSREWGLMILDEVHVVPADMFRRVTERIKTHSKLGLTATLLREDDKIKDLNFLIGPKLYEANWLQLSEEGHIARVQCAEVWCPMTTEFYKAYLEAKTTNKRSLLSTMNPRKYQACQYLIDYHERRGDKIIVFSDNVYALKRYAEGLTKPYIFGDTSQRERELVLQNFQQNDAVSTIFLSKIGDTSLDLPEATCLIQVSSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTNEMYYSSKRQAFLVDQGYAFKVITHFKGLAEMPGLHYNNQHDRMDLLQDVLLQSDTAGDAEDITDSLWNDKNVSKSKKKGSGVRRQAGTLSNLAGGDSMAYIEGKKGAANKALAKPRSSFFKKEDRLKEKKKKQAQGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA96</accession>
    <name>A0A9Q8PA96_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 16">Elongator complex protein 3</fullName>
            <ecNumber evidence="16">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_07046</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="16 17">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the ELP3 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763160.1">
        <property type="nucleotide sequence ID" value="XM_047906194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA96"/>
    <dbReference type="GeneID" id="71986924"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07046"/>
    <dbReference type="OMA" id="TFETRPD"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
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        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
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        <property type="entry name" value="Elongator complex protein 3"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="12 16 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16" id="KW-0949">S-adenosyl-L-methionine</keyword>
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        <location>
            <begin position="420"/>
            <end position="582"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
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        </ligand>
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        </ligand>
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    </evidence>
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        </source>
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            <dbReference type="EMBL" id="UJO18794.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="582" mass="66017" checksum="C9431DC911E0FAD2" modified="2023-09-13" version="1">MATMTETWTDSTQNKKRLPAAKRAKLAPENERYIRACADIANSLVEDDEKVQAGGPKKDVNLNSLRSHFAKKHFLGRQPPLTDIIAAVPEQYKKYILPKLIAKPIRSASGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFEQARGRVDQIRNMGHSVDKVEYIIMGGTFMSLSPKYREEFISQLHNALSGYQTNNVDEAVMAGEQSNTKCVGITIETRPDYCLPPHLTDMLRYGCTRLEVGVQSLYEDVARDTNRGHTVKAVCETFCQAKDAGFKVVSHMMPDLPNVGLERDLFQFQEYFSNPAFRTDGLKIYPTLVIRGTGLYELWRTGRYKNYTPNVLIDIVARILALIPPWTRIYRVQRDIPMPLVTSGVEKGNLRELALARMKDFGTTCRDVRTREVGINEAKNKIRPNQVELVRRDYTANGGWETFLAYEDSKQDILIALLRLRKCSEKYTYREELISQPSSLVRELHVYGSAVPIHERVKGKSQHQGYGTLLMQEAERIARDEHGSRKLSIISGVGVRGYYKRLGYYLDGPYMSKDLDQEEADSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAN4</accession>
    <name>A0A9Q8PAN4_PASFU</name>
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        </submittedName>
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    </gene>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
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            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
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            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB07</accession>
    <name>A0A9Q8PB07_PASFU</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO19184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB07"/>
    <dbReference type="GeneID" id="71987375"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07497"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="69" mass="7177" checksum="8D0064864B5821E3" modified="2023-09-13" version="1">MSFEMSETTTEQESLAVPQGQKGYIAAYCAATLFDGTFTGCNSGPKEQPGQAMVLKSNGSTYSVVTTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBS8</accession>
    <name>A0A9Q8PBS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosinase ustQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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    <accession>A0A9Q8PD49</accession>
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    </dbReference>
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        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="KFase_sf"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="261" mass="28604" checksum="350CC5F3961F9393" modified="2023-09-13" version="1">MSSSTTTTTTTTIPIPPFSSLPLDKSGPHHNAWGLYDPTDQLGTLNRLTDAVVARAASEIRTGTRINLDWPIACPSSAGKSSSQWDGVRHFGYQKEGVLYNGVTMDEIHGRNGVEKTDNLGIGAWAEKGIVGRGILLDYHTCRRLPKTPPIHHGDIILLLLLLRTGYLHAYSLLSRPSLESLRSESLLCFTGVEQSEDMMAFMWENFSACPTQEEYHLHEVMLAGRGMPIGELFDLEKLAAEKVNYVPGGVASPPNVVAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK3</accession>
    <name>A0A9Q8PDK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764846.1">
        <property type="nucleotide sequence ID" value="XM_047909538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDK3"/>
    <dbReference type="GeneID" id="71990268"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10390"/>
    <dbReference type="OMA" id="WLELILW"/>
    <dbReference type="OrthoDB" id="5341924at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1013" mass="112988" checksum="DC0FDBBE469A9634" modified="2023-09-13" version="1">MRRWNGLRAPTVAFNTRGRCVRQVLCPLQHLRPYQQATANDRHRDAPDQVRPNRNTTTLSQYAIFSRIKAPERRLEEWAALLDGALPPHLREWSTTPPSLSAIDAAEILLAAQYPSEPKDEPFDLLFHLGMEKGRWSAVVWLIKRLVEKFAVRHEEDSGFAAANAMWNIGRSLEAATDGRVGGRAEALALDFPLNDASSARVAKASLDELTAGRTADFASLEKMQHNALGQIWRTLGAMTKVCAGGDIRAEVLEIIAYLHHKEVMPVSIYHSEPHPDPSAVQQPPLLSLLSSRILTSLSDAAWRAHEKLVVEEAKANDARYLGLRPEVPGSVYRVRVAGLRIEVWMELILWSCLHGGWADQGAEILNMISYDSSWTAVSWREYARSIHSGNRFDESWEYAFKTRASSSMDAPQGEQLQVERTVSAEVVNAYVDAVACTVHTGQTDPELTIASTHKLLRRLKSLLTRSKSQLSISTGSWDALILRSLDAQGVKFEANAMVSDMLVSLSPGLDQGLERKNTQDLPSYVLDGGMAMQGILHRVLYGQIASGNYEAAVAAFSRIQNRADRDKRTSLESFIGQGQPLRPLSEDDLFTSNLPGIEYPAFDVQIPTSILGSFLDLVTKAEDWHLGRWLLHNEDVDGPLIRSEMYHDPFLEPAVIRYAVESNDKGLLAKFKDRNLRPESLRAIFDTQIEAKHWDAAIKILKLLYERRKSWNMTNLARVARVMLKELAMLATGDIGAAREFEAVKRVFCDMCSGRYLSHKRMTDAHALNVRNLLVVLAAVREPLAEICLEIMSPTKRRYDWFSLNKTDFNIVLSGVVDVHGSAAGRRLLEVFWPRSARSVTDSAARMSRTRGHLARVPGGRPDPLDSIERNRIAVRVHEGAIDEQELVVYGGLIPNSETILIILWKALTEVGSKQQDNAHSAGHSAITAAGDDDDGAVLTSKSMVAWGIRRLAELPYVDISVLEQIDGFLAAHEMHDLRAHLSEIVHDAKRDIVAEFEEENQIPHSSEVDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDZ5</accession>
    <name>A0A9Q8PDZ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11102</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765028.1">
        <property type="nucleotide sequence ID" value="XM_047910250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDZ5"/>
    <dbReference type="GeneID" id="71990980"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11102"/>
    <dbReference type="OMA" id="EGYNWGQ"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="140"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="38037" checksum="2C74D3210D652712" modified="2023-09-13" version="1">MEAAALRQPVDTAMEDAGKVEHSLGTPVDPPSINCLDGWIESLMTCKQLSEDDVRRLCEKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYFSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEI8</accession>
    <name>A0A9Q8PEI8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerophosphoinositol permease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765341.1">
        <property type="nucleotide sequence ID" value="XM_047910517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEI8"/>
    <dbReference type="GeneID" id="71991247"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11369"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="303" mass="32898" checksum="2E3616C63D5D64C0" modified="2023-09-13" version="1">MLSYPCQDCSQGRSIMTTSNNTKDIKSPPDLAEEISSYRPRTPQLGLFWMMIIAWGIAAAGAGGEYPVCTTTSTEASNDSPSTRLRRGILIALATDFAVDLGFVIAGCIALIVLSAYNKRATGGGWRICFGLEFVLPAVLFFFFQIGMIESTQYRKYAMKQTMPHGLIVRKYWRPMVGTSLAWFVYDFGTYPFGLFSSTIISHVNPDDSLVQNSGLGTAVNCFYLPGCISGGFLMGWIGRKQTMTPGLACWAVLGFIIGGALGPIHSILPLFILLYVLFQAFGEMGPGVATFLCGAENFATPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF05</accession>
    <name>A0A9Q8PF05_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA wybutosine-synthesizing protein 2</fullName>
            <shortName evidence="2">tRNA-yW-synthesizing protein 2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765755.1">
        <property type="nucleotide sequence ID" value="XM_047910038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF05"/>
    <dbReference type="GeneID" id="71990768"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10890"/>
    <dbReference type="OMA" id="FELNPWS"/>
    <dbReference type="OrthoDB" id="2387925at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026274">
        <property type="entry name" value="tRNA_wybutosine_synth_prot_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038972">
        <property type="entry name" value="Trm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="4">
        <location>
            <begin position="71"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="375" mass="42050" checksum="B61B33FC9D0ED469" modified="2023-09-13" version="1">MERAVKRWLSTSTDPPSIHPPQDLAQKLNKSYTIYGPMLLLPPTAFSGPGPEWENVNQAFQAHDATITRLYEYICKEVKVTHIALNKPIPLHNTAKEDDLEAKESFNNLRSPHNFHPLFALPGYSFGPSTAHSPPTHEDLTSALWITAKQNSIYQTWSPRWTMFSRGNISEKARLLTLPSVLQAVEEGECTAVDLYAGIGYFAFSYVKAGVGKVLCWDLSTWSCEGLRRGAERNGWKVGMFEGGEEGVVEDGARLVVFNESNEAAPQRVEKMRARLPPVRHVNCGMLPSSRDSLRLAASVLDEGHVGWAHVHENFLVEEIEQKAEETRRELESLLRLQRGGEVSTKVEFINRLKSYAPGVMHCVIDIVVYPRDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGI9</accession>
    <name>A0A9Q8PGI9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766434.1">
        <property type="nucleotide sequence ID" value="XM_047908905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGI9"/>
    <dbReference type="GeneID" id="71989635"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09757"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="458"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="949" mass="103376" checksum="3D6C9381E6C1AB98" modified="2023-09-13" version="1">MQCGVTSVCLHVLCWKEDRVRPDCFDPSRSTWPHAAMGQDFDLGLPTSEPPPYVYSHAYKHRPSRRLGRWQVTALFLSSALGIAVLTRIRWTNSSVLSIGHQTVLEDGLSRCAQLSATFEARPDIQRDNPRWSIFAGQKKPVLLHNATLFDGEAFLPTGVDILFGKGIVRSITPMNYSDTVPGENIEILDLHGRYVTPGLVDMHSHHLVWPFHSLPATRDVNEAPRLGPLTPFVRSFDGFKPYDPAIEIIASGGVTSSLILPASANIMGGEAYVVKNAFVNGKRGEPVVEELLIDYGVPREQRQRYAKMACGENPKHTYLHTRLGNTWLLREHFSKAQDLIHRQNQWCQAASAIAKDSWLASGGDGREPGSLPEDIKYESTIAILRGQVNVNIHCYEPEDIERMLAVLHEFGVHPRAFHHALEAWQVPEFLKQQERNITIATFAENAFFKAEAYNANLRAGKILADHDVPVAFKSDHTGEGNNIQYLLHQAAVAHSFGMPAVKALQAVTSVPARSIQQSHRIGGVKPGYDADIAVWDSYPLSIGATAVEVFIDGRATIGISQKDLEVTELNRDHHREPRPRPTVLEPEKHRFCTAVKKPATKLVITGIAQVDLETYISPLNGHNLTLVIDGGKITCLGSAWLCSEAATDGYVVELQYGHITPGLIAVSQTLGVVEITGEPTTSDGVVDPKADLANEDTIIYAKYGVHLEGRGFERARLGGVTKAVAAPGLRGGLLQGISVGFSTSGKKSVLDGGIFQDDVALHFELSQASKAADPTISNAIARLRRLLSNAPIGEIPVVVHVVNTDLIRQLIWLKRDLPGVNLVIFGGHGAALVAPELASANISVILTGHRGVPDTWEKRDALSGPPLTESPAKILADAGVSFALAIQGDSHVHNLASEAGWAAKHAGLNRTEALRLVSGNVESILSLKRTNDFVVWMAIRCEAKAVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHK4</accession>
    <name>A0A9Q8PHK4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766944.1">
        <property type="nucleotide sequence ID" value="XM_047911009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHK4"/>
    <dbReference type="GeneID" id="71991739"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11861"/>
    <dbReference type="OMA" id="CIFAKND"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="17695" checksum="2CE15BD7BAA10178" modified="2023-09-13" version="1">MRIFAPNDVVAKSRFWYFLSKLRKVKKANGEIVSLNKIQEKHPLKVKNFGIWIRYDSRSGTHNMYKEYREMSRTDAVQSLYQDMASRHRARFRTIHILKVVEVEKVDDIRRPYIKQLTTKDLKFPLPHRAPPKRGKKIFAATRPNTFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ40</accession>
    <name>A0A9Q8PJ40_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="1" type="ORF">CLAFUR5_13130</name>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="48134" checksum="CFF79EA490875549" modified="2023-09-13" version="1">MPLLTEAPALVRRMRDENIDASLRWTPIIQPDNTPISQEQLAAEVKGIYAGLVMVKAKCINIDAARAADPSSQLGPEQWQALIALHRTLLYKHHDFLTATQHPSATHALRRLAASYRMPARMWKHGIHAFLEVPRHRRPESQEYILAFIYLAYQMMALLYETVPEFTDTWIECLGDLARYRMAVEEEKEAHATWGGVAARWYTAAAEHRPAIWRLYHHLAILERPSLRKLCMYTKSLTCVLGSSNMRESFAALREPLLQEQNIQYAGARIATNRTIIYTRSHDHTVGTVHSNALQSLHKQPDRLHGIGSFFTVPIMAALFELDCDPNIWSTLATFLNTIIKSSVVRVPICGATFDPQGAELEWRPLSEDYLTQGVDDENHLYVVSATNLSSCYERAKYSHAGASWARRARNAGEAAANRGLPAKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJE2</accession>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849:SF1">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13145" checksum="84E7029370B9B48B" modified="2023-09-13" version="1">MAARLPTTTLRALSSRPTTAFAPTTLRQHALLSARSFQTSRPMMADTVVSPKKPIGAFRGSLFGFLLGTVLAGGGLYYYVVDEYKVSNELLVEDIYALQSAVQRLEGYVKALETEVKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKB8</accession>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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    <dbReference type="GeneID" id="71992511"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <end position="91"/>
        </location>
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        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="310" mass="35186" checksum="721BDDC4E5B413F4" modified="2023-09-13" version="1">MAPTGEAYEADWILSNSSNAHVATHRDWFTSITPFDTSIYCSFPTDRCRVMGIGEVHLEVKTDPTSTGSRSHKTLILHDVLYCPDLASNILGGHIHDDFPLGEATTRLVDLNGEVGCVFDRVEIKEPGFRKEYKSKVWLEGHRQGYFSEGSGLPWKQAIWPGDEMQRWEDYKAVYDWSMTVHSMSAPTTLPEAGKPKLLVRAFSVKQRKIRKPRPRTPQTESCASSLVADGVTKPPPYTQEEKDWLREHYGEDFRFNGLSLNEDAAYSDGRRTMSLTRHSMMRKDTNRVGSLRSRGMHRVSSIFGSLVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKD2</accession>
    <name>A0A9Q8PKD2_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_13063</name>
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    <organism evidence="2 3">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768444.1">
        <property type="nucleotide sequence ID" value="XM_047912211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKD2"/>
    <dbReference type="GeneID" id="71992941"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13063"/>
    <dbReference type="OrthoDB" id="5357734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="591" mass="64607" checksum="DB1215BC8E92B438" modified="2023-09-13" version="1">MSEGRREHESSQSLLDSNTSWKVWKRGRGHTPKMEKQPKMNAWQPGFLRRIPWGGISCLFGVLCCIVVNIAILATSNGAPITSWKYPPSLYLSVAYTLGNILLSAAFSQGLTIYWWRKALKEGTQLGDLHRYWDHGTSPVAAALAGRNFNFISFAALYLAITPINGPLLQRASTTMTDSQRYLSDDVRVNVPAVTSLQEPSGHTSGRAYIVSMLDANFTPIVQDWNKGLDIVVNHTDCASDGICSGTLQAAGLAVSCNSSTADFDLSYTSSDGSVNQQSFDGLDIFQVDFSWSAMTPSNITLDLQFKPEKDCSQGKLEVRNCTIGAATVEYPVTINGNKSTIALDPNSNIHTDRLLELVEYTPETMYGLPSPLGGYAYALSSRLNSATRLSFAGAAGYTVSSDGSLAAQFADLDDVTDYTSGMCYTKFTDPTEYLFERARDLMFRAAIAQGNATTLQEMQQTSEVRTVTVYRSHFEYLAGAVALTFLAMIIVMCTFNGFWLLGRNVTMSPIETAKAFNAPLLAQEHPNAEVTELVRGAGNKPVRYGEVMDSSQAAFDKGSEYGHADTVELRQLPLAIDNPANVQPLGKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKL0</accession>
    <name>A0A9Q8PKL0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768544.1">
        <property type="nucleotide sequence ID" value="XM_047913164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKL0"/>
    <dbReference type="GeneID" id="71993894"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14016"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="19796" checksum="718456A76525E303" modified="2023-09-13" version="1">MGFANLRYRAQHPHVSGTTSSATARAASKVLYIPELLEMVLAQLPMKDLPFAQRVSKQFRAMIWTSRRLRQKLYMRPSDYPPDHAIACHNQATVSYLGRNALLVSRSSQSSCTYSHGVCFSTHSCALSSQPDNATARSRFVHLNIELETQLVKIDFYTPGQTINAFELASRVHQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKN7</accession>
    <name>A0A9Q8PKN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768533.1">
        <property type="nucleotide sequence ID" value="XM_047912731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKN7"/>
    <dbReference type="GeneID" id="71993461"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13583"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF124">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="273" mass="29380" checksum="AB9DA284B6985445" modified="2023-09-13" version="1">MAALGRLANKTAIITGAASGIGRAIAFAYHKEGAKVVCADLREKTKYTGSREEERTTHDSIRDMGGKAIFQEVDVCKPASVQKLVEAAVKEYGRLDVMVNNAGVSLEAHAGFKPVWELDEDIWQGTQDVNSTGVFLGVKYAVQQMLKQQAHASGDRGWIINTSSILGYVGAEHTAAYCASKGAVLNFTRAAALDCAPHRIHVNGVAPGYTESSMTGPIWRDEKAYREKLAMHPFGGRLGQPDDLAKACVFLASEDAQWVTGHTLPVEGGYLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKY3</accession>
    <name>A0A9Q8PKY3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768698.1">
        <property type="nucleotide sequence ID" value="XM_047912701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKY3"/>
    <dbReference type="GeneID" id="71993431"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13553"/>
    <dbReference type="OrthoDB" id="3650836at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="26353" checksum="1C54A2E6C9AE85A3" modified="2023-09-13" version="1">MVLCLPKSGVKIQYASASTYTLGVWDREHSDTSSIMSRPNYPQIAYHPPLSAGPLSSHLALLLTSKQIYQEAMPVFYSENNFITGLGPFDISLQALKPRCAGHIRHISVYWEPLGTAKTTVACFTAMKRMQNLRVVDIYFDTEEWKELKKPCNAGNTFIPEKLPGFAKLRDLYNTRQVTVYGDCDELRSALVAAQKQAREIKEQRLTKRKATAAGSSKGLGSGSKPKKAKKAHAASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL14</accession>
    <name>A0A9Q8PL14_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768789.1">
        <property type="nucleotide sequence ID" value="XM_047912661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL14"/>
    <dbReference type="GeneID" id="71993391"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13513"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32263" checksum="38F25369D05B0A3B" modified="2023-09-13" version="1">MSHGLAASDVDGSLQRSDAYKMAQLPQLCYFLQGKGELDKKLNISVVSYSGDENGVKLEGACEALARAQLLTPREAAAKGFKSIYLRNINNSHYEYYTQLLDPADLSTWPVYDHYGTDLAGIVTDPRDQDCDHDVMVSLELLHDSCDDVTPCRVMREAVNARGSFDPSDTGYSPMLADAEAEYNSPPSPPTSGNDTQLDSSIAGKKAIDTTEQDAATVKQTANAMTQAAVTDRKREQVELDKKPQLAKPNSKKHQARSGGGRGWGKRLRRIFKTFGIARATGGSKPEYSNPLAPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLB5</accession>
    <name>A0A9Q8PLB5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="29486" checksum="6C3A2AC31A4A2EE0" modified="2023-09-13" version="1">MPALPEERRKSHTFESLSVRPVDFSLTSGTNIPAPLDSPPVSLSPVESVRLSRPKTLSRPPTAGGGPLSSHPTNDIMPMPGALPPTPEPERENNTNHTDTTMHSEESNRDGAASWRSPTPNTNISQTSPGRRPGGVRRLFGLTSLRQSFSSSRTSFSIPPPSSSYGEQSTMQRPQSPGVMSTTASFMPPPSMHSNQQATLRKKRSSNWFKRKSGFFTTNENGFLDVVSEDPRPDSKRAKRSDLPMLPEISTLSGDSVGEGSIGWDEGLFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US44</accession>
    <name>A0A9Q8US44_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF833-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764747.1">
        <property type="nucleotide sequence ID" value="XM_047909420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US44"/>
    <dbReference type="GeneID" id="71990150"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10272"/>
    <dbReference type="OMA" id="WPKIIDG"/>
    <dbReference type="OrthoDB" id="191601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37293" checksum="5F66708F6B0CF25D" modified="2023-09-13" version="1">MCISVLSTTHPDYPFILISNRDEFVSRPTLRADWWDLPNAHVLGGRDLQRQERGTWLGITKQGRIAILTNFREEGDTEINQAKSRGAITNSYLTIPPGSGETEEDLAERLMKDVGIRDMGGFTMLYGKLRAPTQTGGNMPGGNMPGLAIISNRTESSIKLRRIATQQDEIHGVSNSHFGDTTWPKVVRGEELLDRIIQGNISSSSQSQGHFVEDLFSILCVDDIPKRKIEEDWDMYVRHMRSSIMIPPAKGQIIENRAADQLRVGDAGGTETPDHAKVEPGRKAYGTTKQTVILVDKQGKVTYVERTLFDEAGAPLTTGDRDVKHEFMIEGWKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USP5</accession>
    <name>A0A9Q8USP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765420.1">
        <property type="nucleotide sequence ID" value="XM_047910009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USP5"/>
    <dbReference type="GeneID" id="71990739"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10861"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="393" mass="41234" checksum="658611D95D27873A" modified="2023-09-13" version="1">MPIKVNRLPISVADLRVFEGPKDAIKLGVLFDINHRFGIKQIAHNWTVIHPNEPQLKSLTLSNRLVNAKKKITRDTGRTHDELSQELEDALDLVDYKTNGKNKEVEIPYQPTSQAASGAAGPAPPPPPPAPTTDDTDDKDENKNKVQAGGGEVENEESDGENGAAGSLTEQPKNKGKKRAASEDTEPQGEKEGPPSKRAKANSAPGEEPPEGGETGSAVDVAGGQDAASPDEGAGGEAARGAEIDDDDDAAQDGGAGEAAGSGEAQRRGVVYGGAVETTPGDPSTTTPGAEWNPTQYAPSVLTNSREDVGGEPPLPKLRQVQYEKMGLEGTARLPKKEQAKLGKTKLDFVSGEGKAAQAGQDVPEAEGNTEEDVDKDASTEDVEEDGEKENDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT64</accession>
    <name>A0A9Q8UT64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09709</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765858.1">
        <property type="nucleotide sequence ID" value="XM_047908857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT64"/>
    <dbReference type="GeneID" id="71989587"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09709"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="28398" checksum="50B996CC26C59C0B" modified="2023-09-13" version="1">MPPGTKFPYNPSTSIPNLSGKVILITGANTGLGKATALELSRHGPAEIWMASRDVTKGQKTVSEVQATASPGTKIQFLQLDLSSFASIKSAAGAFLADAERLDVLYLNAGIFGAPAALTEDGYEVHIGINHLGHALLLKLLTPLLLSSAALPPGSDVRVLGNLLYAQEVAERYPQFKTVAVRYGEIGTELFSREAGDEQNEVAPLHDIGIEEGVKNPLWAGTAPEVVSGTYYEPVGVGGVATGLAHDREMQNKLWEWTKSELAGHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTC3</accession>
    <name>A0A9Q8UTC3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 monooxygenase TRI13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_09277</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to COQ7, therefore facilitating the COQ7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765991.1">
        <property type="nucleotide sequence ID" value="XM_047908425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTC3"/>
    <dbReference type="GeneID" id="71989155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09277"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="15">
        <location>
            <begin position="762"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="577"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="598"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO21625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="861" mass="96426" checksum="DD1CFFA54929A6A8" modified="2023-09-13" version="1">MASLVYGLLALLVGIGAFSMYKFALPKPLPGIPYDIASRKRVLGDLPDATAWMRERKEFWSFLQARCQQLNSPIVQVWMQPLGKPFIVVSDYLETQDIMVRRHAQFDRSAWLGDMFWAIAPRNMTRFLTNDDWRAHRRLMADAMSPGFLRNVASPHGHAGASSLIKLWKSKMDLAEGRPFSVFDDVIKSAMDAMWSAVFGSEISTTQGQIDALTGRSVLLSSDRNVPVEFPQADDPETFTAMLTLGNSVAWAASSPLPKTTHWLAVNLIPNLRRAMKLKRDYLSGMLHAASHKFATSQDEGKVKHVLDLVVQREVTLAKKEGRAPEFDTQDIRDELFGFLLAGNETTSATICWGLKMLSDHPRVQHKLRTILQEFHIQARQEGRTPSPQEMFNANIPYLEATLAEILRHAGSAPGSTRRTMENTEIFGHQIPKGYDVLMLMNGAGYTSPALPIDESRRSMQSVKASDIAGMWDESDISQFVPERWLVTDEKGQVTYDQKAGPFQSFGAGLRGCFGRKLAELNLWTFFTLILWEFELLAPPESYRSYLGLDKSMHQPQQCYYRAHSIEREPINPTLALSEPKSSIQPSRLHSDTTHLSRPPPPPPPPPPPPPPPTMALRTLLRTPPALRSLLLQQTASRASYHSYEHIEPPPYRETESAILSSALRHVPTHGFTQQSLTLGAKDNGYLDISTNLFPNGAFDLVLYHLVTQRLGLKDRIHFPENIGVGRKVRSLILERLRGNDDAGVVGKWREALGLMSLAENIPKSLKELAALSDEMWFLAGHVSVDSTWYTKRASLSGVYAATEVFQTTDQSTEYRDTEEFLDRRLEEVRVVGGAVGGTIEWASFQAGSVVNLLRSKGVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTL8</accession>
    <name>A0A9Q8UTL8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proline utilization trans-activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766319.1">
        <property type="nucleotide sequence ID" value="XM_047908637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTL8"/>
    <dbReference type="GeneID" id="71989367"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09489"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF32">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="676" mass="74627" checksum="FBF4957C7B52A89A" modified="2023-09-13" version="1">MDEVVKSGRVRKRAPNACTRCRKQKIKCSGNVPCEQCSRRNVNCAFDDKQHKILVSQTYIAELERRAAGQSPHNGNQIPPLHHIGLDNDPGSPGEHGEPSGHGNIHHGPGSDDIEDDHASPSEPSTQGQTAVRTTPEANLTNPLDPNNSDSFTLDTASRRFFLGVSSNWSFGRRVLRMVHEKVNDTPLPAEGLQFEGSTYDLGWDGHRRTVAVDTSSLPTSDFAVFLINAVKFHCGRLFHLFDETLFMHYFTRFYEDPGNEANYPRLWFIHFLLILAFGKAFIVGANKSKRPPGAELFVQGMQLLPDITGLYTDPVQSTEVLCCAALYLQCLDLRSAAYNVIGQAFRLAVEQGLHTDMQSLHLPDAMVERCREVWWTVYILDRHMTSLMGVPMSLSDDEITACLPTFAGQTKKAIALSLHVRLAKAEAVILQTVYGRGGGRSERFLLNMKGALRTIASANEQRNASFPLDLDNTSILSHTGNKTVTLFFPTEATGVDKAIASVCVARRQIARQESFIPFDRDAAFSSAVVLNVAATVDPSLVKNKDPRLQTALAILDEMTTRGNRIAEFHKFELEQLAANLRRLQAMSSAANEGRADSTSQVSPNETTSLSVAPMDGQNSEDFQTTFDNIDTILSEWNSDDGLSGEHLMAVADSLDFGQLNWLTMGDFEQPMSVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTN9</accession>
    <name>A0A9Q8UTN9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766381.1">
        <property type="nucleotide sequence ID" value="XM_047908882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTN9"/>
    <dbReference type="GeneID" id="71989612"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09734"/>
    <dbReference type="OrthoDB" id="3650781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="65"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="302" mass="34787" checksum="49625AD1BD07A54D" modified="2023-09-13" version="1">MDYQFEGVLHRSQEALRLEMRQTYPFLDDVALEDMLCEAGGAMRKRMQEQAPIMAAAEARFSIFKLPPELRNRIYELVLGPPKHICVQRTDIFYTANDGDTYYAGYGNCYSEYQRPPPITQVSRQIRAETTPIHYGQHTFVAYVDSDPFRWPDTPDEWTQWRSDRQYKKWTRGDPTTGGVRDWLDRIGSHQASLIKHFLIRIPLPEPTCTWKRQASCSKADCDEWHPSSSAQVSKYLGIQALGVKDQAVKASFGATCGGIEWKDSSLAHAPLDWSPVGNETLANNEKFASEDVWRYDHWRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU35</accession>
    <name>A0A9Q8UU35_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell membrane</location>
            <topology evidence="1 6">Lipid-anchor</topology>
            <topology evidence="1 6">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766829.1">
        <property type="nucleotide sequence ID" value="XM_047911137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU35"/>
    <dbReference type="GeneID" id="71991867"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11989"/>
    <dbReference type="OMA" id="ANHDGCM"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000038">
        <property type="entry name" value="1,3-beta-glucanosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF8">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040537834" description="1,3-beta-glucanosyltransferase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="436" mass="46915" checksum="540696F945E0A429" modified="2023-09-13" version="1">MLALFIALLFATTAFAVPTIEAKGARFFTSDGDQWFIKGIAYQLTPDDPLAQGDQCKLDAALMKTLGANAIRVYHVDPAANHDECMSAFEDAGIYLFLDLDTFSTYILPDDPHWNETQFNEFGKVMDAFHNYDNLAGFFVGNEVLTTGANSIAAPYVKAATRDMKAYRDSKGYRQIPIGYSAADIASLRPNLQKYMACGDNSSDALDFFSLNAYEWCGETTYETSGYSQLQQNASEYNIPIFFSETGCNTPKPRTFADQSAILGEEMSGTWSGAIVYEWIQEANDYGLISYGPSVDPTATGANVVGGFTVRGTPTPISPDFDNLSKQWATLSPSGPPASAYSPSLTAPACPEYTKDLWNVNRNVALPTLGQTFDAQVSSSITAGGTNTGSTGSMAMATAAGSATRRSSTSSSRAVATGMPSPEIWWLAAMFPVVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU47</accession>
    <name>A0A9Q8UU47_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Indoleamine 2,3-dioxygenase</fullName>
            <ecNumber evidence="5">1.13.11.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Produces N-formyl-kynurenine through the oxidation of tryptophan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.52" evidence="5"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766803.1">
        <property type="nucleotide sequence ID" value="XM_047911413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU47"/>
    <dbReference type="GeneID" id="71992143"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12265"/>
    <dbReference type="OrthoDB" id="10262710at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.480:FF:000005">
        <property type="entry name" value="Indoleamine 2,3-dioxygenase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF3">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="591" mass="67077" checksum="564247DD767BF0F6" modified="2023-09-13" version="1">MSTGQANHEGTPRDMVIFGFEEAGMHSGHGIHIHEIPQIELAFFSLPKATQYHSPEQHFVLHVTRDPCQDSFLFLTFFASHSSTMSPFLSSNLGHEDEPRQTDTKAVFPHIDAEPAVLPSSLDPFTITTSNGFMPLQTPTTDLPDAFKPLLDLADEMPIVKEDGQPGLLAKYELGAAIDEKKLLPDLTNEIDSLVTADGQPDLVAVTAAFRDYSFLASAYLLEPCWERWSKGLEGYGLGREVLPACLAGPLWKTAKMLEIPPFMAYAAGYALYNWRFADPSVGYDEYYNLRLIRAFEKGLDPYSSEAGFILTHVDIVRHTGGLIEGAVKTMDAVAADDGSANVADSLEVLLNTMHDIEESMEKMWAHSKPKDYISYRTFIFGITNQSMFPNGVIYGGINDNKPQYFRGESGANDSIIPLLDHLLEIPMPQNPLTEILKDFRNYRPKPHREFLAYVRERAEQIGVKQYCRKNLDTKVKYLRLLEHVRSFRWRHWLFAREYIIRRSIHPTATGGSPIVTWLPNQLFAVMELMREVWESITVEERDAQGKTVNEMMENVYDSYDKLQKEVQRWCKERDPKASQAEAEALRRLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUV5</accession>
    <name>A0A9Q8UUV5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767523.1">
        <property type="nucleotide sequence ID" value="XM_047911277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUV5"/>
    <dbReference type="GeneID" id="71992007"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12129"/>
    <dbReference type="OMA" id="FNAWDTA"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00877">
        <property type="entry name" value="Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000131">
        <property type="entry name" value="GTP-binding nuclear protein Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="24118" checksum="DBD9225A48660A53" modified="2023-09-13" version="1">MAEGTPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLGFTTNLGQIQFDVWDTAGQEKFGGLRDGYYINGQCGIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLTGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGNQSLEFVAAPALAPPEVQVDQAAMEQYQKEMADAANMPLPDEEDPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUW3</accession>
    <name>A0A9Q8UUW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12672</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the assembly of the cytochrome c oxidase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the COX20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767684.1">
        <property type="nucleotide sequence ID" value="XM_047911820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUW3"/>
    <dbReference type="GeneID" id="71992550"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12672"/>
    <dbReference type="OMA" id="NWAVGMF"/>
    <dbReference type="OrthoDB" id="14603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007871">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="23533" checksum="5A518FE1713C469F" modified="2023-09-13" version="1">MADDTRQPNGQPKGAIQEDLSCEALTAHPENKPFEGQQWQVQNGKTMPYKPPENANMMPGGTQHTAGGETPEVNLYNALHVGQPITEIHKRPCVRDALLTGIGGGFATGGVRAIFGAPIFKACNWAVGTFCVGAGIMYQTCMYKRQAEKEGMMRAVEILNKKEMEKKAREQRKEAMREERRQAKEKEQDAQFAALNMAAPSGNNGKPWWKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY6</accession>
    <name>A0A9Q8UVY6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-dependent mannitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768708.1">
        <property type="nucleotide sequence ID" value="XM_047912637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY6"/>
    <dbReference type="GeneID" id="71993367"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13489"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="30245" checksum="752FAA378458B78E" modified="2023-09-13" version="1">MTANGTSEAVNGNVPHTSTPSASTSTTTATPVTQIQLAGKVIAITGANRGIGLGIANSCLSNGAEHVFSIDIGDAGEDFLAVQKKYPGKLHAIKADVTSEASATKAVDQIIEQAGTLSGMVVNAGRTNHKAALDFTEEELNQLFSINLFGSFYCARVAARAFIKLGVKGSIVFTASMASYRPNKRVPSAPYGASKAGVRNMTHTLAMEWAQYNIRVNSVSPGLVNTAMTYWVPQQPDWEQQLKYYGGMPRLAEVEELGGAYVYLLSDAASYTTSIDIPVNGVIGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWI7</accession>
    <name>A0A9Q8UWI7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-carbamoyl-D-amino acid hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769396.1">
        <property type="nucleotide sequence ID" value="XM_047913644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWI7"/>
    <dbReference type="GeneID" id="71994374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14496"/>
    <dbReference type="OMA" id="KIHLPGD"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF6">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="629" mass="69098" checksum="29DE16F56D2A1F69" modified="2023-09-13" version="1">MARKIRLAAAQMGATHRQSPREEPLRRMIKLLDDAACTGAEVVLFPETAFTTFFPRYLIEDEAELASFFEYGDITTSSQTAPLFERARFHGIDISVGFAEACDNGDRFNTSIYYHAKSRSILAKYRKIHLPGDFEPFSDPNATNQLEKRYFKPGNLGFEAFRAPDQADDAQPIFGMMICNDRRWPEAWRCLGLQGVEVVLCGYNTAGFAPHLWGGDTKQDPEAAKQNALLHHKLLMQSNSYMNATFSVCAARCGLDDGKYNLICGSCIIDPEGKILAEARTKEDEIVVADCDLDKCRQGKSRTFDFARHRRVEHYSRIVEQTGVVEPLRLVERQHATPVVAIPTNRDGVSEIHDTSQEQHTESVPTASSTSPASPSAKPIRILLINPNATKSMTDACVTSVQSTLPSDIEVHGFTGPADDASTAIESQTDNVLSSAASFRALHPILSSPTNPYHALLVACYSDHALIKMLREEFELPVIGIMEASLFYARTLGSKFGIVATGQRSKIGHEGNVRTYGMEKFCAIVESCDLGVLDLERLPRETVIERMRGVSERLVERGAEVLCLGCAGMTGMKEAVGEVVRGEGVEVVDGVVAGVQHLVGVVRMGGRTSKVGLWRSSAAGRERRGQGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWS6</accession>
    <name>A0A9Q8UWS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14324</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769697.1">
        <property type="nucleotide sequence ID" value="XM_047913472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWS6"/>
    <dbReference type="GeneID" id="71994202"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14324"/>
    <dbReference type="OrthoDB" id="2849579at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051438">
        <property type="entry name" value="RNF_E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46016:SF1">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46016">
        <property type="entry name" value="ZINC FINGER, RING/FYVE/PHD-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO25331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="105" mass="11577" checksum="52D34868FAFEDBD1" modified="2023-09-13" version="1">MSLPTRSQLLLTLTRDTHQDQASNTASNTLTECPICYDIVTNTFTTPCNHTFCHGCLSTWLRTSTTCPNCRSVLCEQPARRQIERFPRAAAKEQRAASDSGGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5T9</accession>
    <name>A0A9Q8L5T9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755703.1">
        <property type="nucleotide sequence ID" value="XM_047899702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5T9"/>
    <dbReference type="GeneID" id="71980432"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00554"/>
    <dbReference type="OrthoDB" id="5206740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="35231" checksum="AEC4C599913FD1D6" modified="2023-09-13" version="1">MLAFRQQSPPLPVHAPAASDTMSLAILPSAAPMACGQLPVPALLPPSPAPSKRPRLSLNTTSIPSTLYGKGSTSLRLETLSATSPTIRNTFSNAHDRLNAQSRPLARSSKPALAPLATGSTTSSQQSPESTTQNSASTISSTSSSSAVSTGEIFAAPERIPYKVSYNVTSILSNSPLPRRRTRRMSLTQSKPMFPATKQVSFRTPLTEDIKTSTYTMKHSDIESSTSTISTLELSPTKKTATSNETTDTSDDDAEKKDESSESSSSPQTGDKRQSSDEEDSDTCPATPVAGRKKRHRQWVWTLGPVATSKDQDSAEVTIRNDEKLDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5V6</accession>
    <name>A0A9Q8L5V6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755747.1">
        <property type="nucleotide sequence ID" value="XM_047900828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5V6"/>
    <dbReference type="GeneID" id="71981558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01680"/>
    <dbReference type="OrthoDB" id="2420454at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF27">
        <property type="entry name" value="NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="97"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="25650" checksum="4A4731D23272D031" modified="2023-09-13" version="1">MLIPCEGYVGKKHVVGVTILPAALTWIVDLGISRRKVDDHVPWQRFNIVNSFFQHNTTNTMPEPLALDLASKRTRTRNDYVYLEDYRSRWNDNDMFHHLNNPIYGVLIDSIINSYLIQKTGYSTSESEFIGLVGSSYCDYFGSAHYPGMLNVGLRVVKMGKSSVMYEVGVFQEGEDQVKAVGGFIQIWVLRKTNKPTAEGIPQHVRRELSTLLQGSEQDPTTKSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L787</accession>
    <name>A0A9Q8L787_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Laccase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756466.1">
        <property type="nucleotide sequence ID" value="XM_047900885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L787"/>
    <dbReference type="GeneID" id="71981615"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01737"/>
    <dbReference type="OrthoDB" id="3645735at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04206">
        <property type="entry name" value="CuRO_1_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="95"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="227"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="440" mass="49318" checksum="4B7A76753F5BE491" modified="2023-09-13" version="1">MEKEKSKKWRTCLSAAAITAAAVLLFFLYPKFDSARTWATDVLYAGAEPEITIETGHGPLARPDAQAPDDLSVRLHPDRHIRRAAQAIELEWNVTNDWRWPDGVAKEVYLINGEFPGPTIEVRSGDELSVTVHNQLEGEEIWIHWHGLRFENQAEEVLGLTRCAIAANASYTYRLQVSPEVHGTFWYYSQAEMQRGDGLFGTLVVHEPRKDLDEDSRPPPDLNIQEDQLLLINDWYHQPSSDVLAAYRDGEFFDAAPPPDSILLNGRGYFDCSKAYDEPSMDCKPMDMPHLTFPDRARLRIVNAGSLVGLTISTVGYSMTVLAVDGGTLVERATFEKLGVLYPGQRMDILFERRGDDQYDSAWITIALDRETMQYPNLVLTDTQQFHIATSRVTNKDALERGGPEIDSGKTNNPFLDLSNVKAMVASTSELGKKADNLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L834</accession>
    <name>A0A9Q8L834_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757017.1">
        <property type="nucleotide sequence ID" value="XM_047900821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L834"/>
    <dbReference type="GeneID" id="71981551"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01673"/>
    <dbReference type="OrthoDB" id="5399555at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17223" checksum="16339F637E4E3C8C" modified="2023-09-13" version="1">MTRNDARFSTYSGAPSLQPSLAPTLDTTSNRSSTNHYTTSRFSEQTFLTPQTIPENGGRTVYGNTAATGSSLTLSSTDPKTAEIKCFANVLDRMSDERADKQRFVMNAHKTEEVSKIALGAKVERALSRRMVGQDAVFRAKAKCPIDEKRALEVEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8Y2</accession>
    <name>A0A9Q8L8Y2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NDUFAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757466.1">
        <property type="nucleotide sequence ID" value="XM_047901504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8Y2"/>
    <dbReference type="GeneID" id="71982234"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02356"/>
    <dbReference type="OMA" id="MINAREQ"/>
    <dbReference type="OrthoDB" id="270318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21181">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21181:SF13">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="395" mass="43572" checksum="DB95CB03B584ECB6" modified="2023-09-13" version="1">MLAMATRSVLGRSWEGCRATAAETRFLAAQSPRRCASSDVNAAPAAVPSSKEMASARTFCLDLLRKYDMPSSLLLPYIPSHARDAYIALRAFNIDVARTADTTSTPMIGSMRLQFQRDAVTKSLAGSPPKQPIALLLALAAEDIQARSEGKQKFSKSWFLRIIDTREKYLSNPPYQTLEDLERYAENTYSTLLYLTLQALPMASLTADHIASHIGKAAGIAAVLRGLPLIAFPGPQNHHSNQGQFPGDVGASKHGAVMLPVDVMVDAGVREEDVLRSGADAPGLRDAVFAVATRANDHLITARQMITNIKAGQEAGHEFEHQDEEEHAYLPSTGKQETQAQEVERAFGVYMPAVATQMWLDKLQKHDFDVFQPKLRVTDWKLPFSAYWAYSRRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L965</accession>
    <name>A0A9Q8L965_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Asperlicin C monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757473.1">
        <property type="nucleotide sequence ID" value="XM_047902548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L965"/>
    <dbReference type="GeneID" id="71983278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03400"/>
    <dbReference type="OrthoDB" id="3649008at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="518"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="531"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="552" mass="61032" checksum="811032254A6C88E8" modified="2023-09-13" version="1">MHKIVYNHDHAMAQGVDIRLAQQVSHQYFENDKEARVMSNGQRVVAHVVLAADGVRSKARDLVLGYHDKPKPSGYAVYSAWMSSEDIAKNDLTKDLVIHGDSHVCWIGPDIHFIAAAAVKRGKEILTYGATTPKHMLTRHIQAQALQEHHQQLLTNLEPHHNMAHSGILFDKKKNASFGRLHVGYRASHWTKVWYQPAPEAEVDDDGTVEIGLFKLSTGGATRREPMMGEVVWLPHFELKVFKSTKNAEKERLQMQYLYDAWRYLNEPDPHQVLQLEQELDDPFNRQWQSWFEDAKKWKSSKLRRRSKRRTARTVAVRSAGIDLDNVEVNSDTSEDSAYESEEDLFVRDKEPIGPPGSTGKRKAGGNGGGPPNKKSPNKSKSSPGDKAKPRGRASDQDVPISGGLGDMRDRGGLGGEKHLGGSLFGRLSFGSRTNLPGLDNDEDNDNASRGSRGSLTYDNRSPEPLPARRNGSASNTSTVGQREAGQAVLRDRFKHPAAAEAARARLHNGDLGESEAFNWAIRESSQLPENGSNGSQSNGQNGANGTGEHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA33</accession>
    <name>A0A9Q8LA33_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03289</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757951.1">
        <property type="nucleotide sequence ID" value="XM_047902437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA33"/>
    <dbReference type="GeneID" id="71983167"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03289"/>
    <dbReference type="OMA" id="GQPWFSD"/>
    <dbReference type="OrthoDB" id="409947at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001409">
        <property type="term" value="F:guanine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000010">
        <property type="entry name" value="Probable YHM1 (Mitochondrial carrier)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053042">
        <property type="entry name" value="Mito_GTP/GDP_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974">
        <property type="entry name" value="MITOCHONDRIAL GTP/GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974:SF1">
        <property type="entry name" value="MITOCHONDRIAL GTP_GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="218"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="33511" checksum="133BBF36C4470FA2" modified="2023-09-13" version="1">MSPSIPAAKVGSAKDNQRESTAARILGAGSAGIAELIVFHPVDTIAKRLMSNQGKIQGAKQLNEVIFRKTASETAVKRFFSLFPGLGYAAAYKVLQRIYKYGGQPFVRDYLSQNHGQVFDNTFGKGNGKAIMHATAGSLIGIGEIVLLPLDVLKIKRQTNPEAFRGRGVMRIVADEGFGLYRGWGWTAARNAPGSFALFGGSAAAKQYLFALEDYNSATWFQNFVASIAGSSASLIVSAPLDVVKTRIQNQNFEVKKSGMKIITDMARYEGMTAFFKGLVPKLLMTGPKLTFSFWLAQTLIPAFNKMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAH7</accession>
    <name>A0A9Q8LAH7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758277.1">
        <property type="nucleotide sequence ID" value="XM_047901899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAH7"/>
    <dbReference type="GeneID" id="71982629"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02751"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20568">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="364"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="457"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="461"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="600" mass="67283" checksum="3AE6EC882C1C736B" modified="2023-09-13" version="1">MDAKPQRPLARAIRVHDENMPPPTNGPIGKTLHQRTKSTSALGGVALNQKKVLGETNANLRVIPKDDSEIGKASPGKIKIHAEPAAPAQTFQRQAVRPLATKSSSMQIAGAVAATRQAAAAAPEVQQPKKVVPKKSKVLRDPVPAAVQLEAPAKVNNVPVQPSDIVNITAHPQPALATEQSTNNFILQRDEVRRTESVPLRDEAGPKLPVQPVGAVSSIPAVVSAAPQEHAHQQPIDVLPAHNGPAFQVATPPEEFIEEDFDDQDQDYMTAQSFDMRDATETTIFNPAQTKKNKQEIAEAREWVEANRTPDDIEDEQWDTSMVAEYGEEIFDYMREMESRMAPNPYYMDQQTEIQWSMRGVLMDWVVQVHQRFNLLPETLFLTVNYIDRFLSCKIVSLGKLQLVGATAIFVAAKYEEVNCPTINEIIYMVDNGYTAEELLKAERFMLSMLQFELGWPGPMSFLRRISKADDYDLETRTLAKYFLEVTIMDERFVGCKPSFLAAGAHCMARLMLRKGDWTKAHVFYSDYTFRQLHRLLGAIYECCSNPQKHHAAVFEKYSDKRYKRASTFVGGEVMRGFQLPFSYRSSMGVQNTTGTWIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAJ1</accession>
    <name>A0A9Q8LAJ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4291 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758248.1">
        <property type="nucleotide sequence ID" value="XM_047902049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAJ1"/>
    <dbReference type="GeneID" id="71982779"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02901"/>
    <dbReference type="OMA" id="RDRMTWI"/>
    <dbReference type="OrthoDB" id="413653at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025633">
        <property type="entry name" value="DUF4291"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567">
        <property type="entry name" value="DUF4291 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567:SF1">
        <property type="entry name" value="DUF4291 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14124">
        <property type="entry name" value="DUF4291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="22693" checksum="7C430958D85BC309" modified="2023-09-13" version="1">MSTSYRTIRASFDEDCVVVYQAYNASIASAAVEHQILSASSLLKPGRMTWIKPSWCWMMYRSGYSYKDLNQERILAIRMKHEHFAELLSNACLAESPHARGESVVVQWDPERGPRLEKLDYRTIQIGIPGSIRDKWIAEWIEDIEDVTERARSMKRMLDDDAAIDAGRLIERSLMPEERPCAVDDAIIQRLEMSTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAU9</accession>
    <name>A0A9Q8LAU9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758413.1">
        <property type="nucleotide sequence ID" value="XM_047902174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAU9"/>
    <dbReference type="GeneID" id="71982904"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03026"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="56404" checksum="EE01FA4BDA93DE3D" modified="2023-09-13" version="1">MHLLPSHTDMSPSVLLVNDGNIVDDSGKHGTDADSDSSSALLHRSLHHDPLHVVGAEGNYLHLSNGERILDASGGAAVACIGHGNVRVQEALIEQMSEVSYCHSLFYATTAPEDLAKILIESTDGEMARVFVASSGSEAMEAALKLARQYHLEKPHPEPERSHFISRQQSYHGTTLGALAAGGHVARRAIFEPILSINTSRVSPCYAYRGLSSVVDTEGSYIRRLEAELEAEFLAIGPKKVAAFIAEPVVGAALGCVPPSPGYFAAVRRVCDKYGALLILDEVMSGAGRTGPAPSERHPRPLHAWQDPLIGITPDIMTMGKGLGGGYMPVAAMLANRRVVNTLEQGTGCFSHGQTYQGHPLACKAALEVQRIIRDDDLVTNVRIQGALLGRLLHEKLSHHAAVGDIRGKGLFWGIEFVQNKITKEPFDPSQGIAMAIHELGMQHPHNISLYPGTGSVDGRRGDHILIAPAYNITADEIRQIVDTVAAVVRQYFLQNHKGWLAMHSADGQLGLAEKVKAFQFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAV6</accession>
    <name>A0A9Q8LAV6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent DNA helicase PIF1</fullName>
            <ecNumber evidence="15">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA 5'-3' helicase PIF1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">DNA repair and recombination helicase PIF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PIF1</name>
        <name evidence="18" type="ORF">CLAFUR5_02782</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the helicase family. PIF1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="15"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAV6"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18037">
        <property type="entry name" value="DEXSc_Pif1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001226">
        <property type="entry name" value="ATP-dependent DNA helicase PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03176">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048293">
        <property type="entry name" value="PIF1_RRM3_pfh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 15 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="422"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="15">
        <location>
            <begin position="834"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="79"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="201"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="430"/>
            <end position="437"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO13373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="911" mass="100570" checksum="3DC4200B7AE84FAD" modified="2023-09-13" version="1">MDWTTSSNALGAYLCLATILGLCWMLIVRGAGQAASRLPTPRSLTRVHIPTFATSNTQQLHSLAATRPETTISTMLRRAANEHDRKTEQRLSQTSFGSSQPQPKAASQAVNPGYRNPLRPTSESTLNGLNGYGALRTGGIKRTASGLAKSLDGSFEDDTGSQYRPITVGGRSPSKSNVAQVTQTDLFDENDFDSDIELEIEEPLPQTSISYPKLPAQPTERAKVNDAPISYPTLPKQQPQISPSRNLNTNAGAPASQQAPDSSAPLPWSSSPVEHFSSAAPRVGLQHFAFDPRNSHILKPPDGAQPKPAKRRTLPWLKEGAEESTQTKPTPFMSSTTKSSNGITSTFTPAAKDKKDKSQFPWNTTASAIKDQQKKHREEVRAAKKVAGTEDSLRTAKSTQKRPARVFLSDEQQHVLELVIEKKKSVFFTGSAGTGKSVLMREIIASLRNKYKKEPDRVAVTASTGLAACNVGGVTLHSFAGIGLGKEDVPELVRKIRRNQKAKHRWMRTKVLVVDEVSMVDGDMFDKLESIARQIRNNPRPFGGIQLVITGDFFQLPPVPEANRGAKFAFDAATWPTVIEHTIGLHHVFRQKDPIFAGMLNEMREGRLTQSSINAFRSLSRDLRFEDMLDATELFPTRNEVERANQERLVNLQGQTFPFPARDGGSITDKAQRDKLLANCMAPEMITLKKGAQVMLIKNIDETLVNGSIGRVIGFMDERQFDSYNTNEGAFLQSPGGTILGSGDNDAPDRPSMMQGITTSRKWPLVRFAIADGTWRDLLCEPETWKVELPNGEVQASRAQVPLILAWALSIHKAQGQTLERVKVDLGKVFEKGQAYVALSRATSMAGLQVLRFDPRKVNAHERVRAFYTKLARVELADKNKERMEKINMPSTTNAGDYEKNFVEGDFAWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAX4</accession>
    <name>A0A9Q8LAX4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758388.1">
        <property type="nucleotide sequence ID" value="XM_047901654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAX4"/>
    <dbReference type="GeneID" id="71982384"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02506"/>
    <dbReference type="OrthoDB" id="3867271at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="36620" checksum="BC09076898BB291F" modified="2023-09-13" version="1">MSCEVANASPFGDPNEWGKVESPGGGLDAIVNFNASFLPQDGNTVDPQLFSNSPAPNEYHHSTYNVPSNGLDQTLSAEPSPFGDYPADFNQAPSSPYFPSIEHPPQQIYHPSPLRNNAFRRSVSEPPGGPDLQQPGPPPMMFHREHHYLGKPMPRQAVQLKSLPKAKQQRPHPYQRAHTRRVNVPEPGPPFRPEHRRAHTSGGRTGPTSSPMMMMMQMPHQQQYMPHAPMMQEPQQQFVSSRVCTPVPEMPQIDPALSGSSTPMPAYMHSSPRNAVSIPLTVDELRSMIFEAVQKAVGEKEKKDSVAGVSPRNMAATVEDREEAEAAKTEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAX7</accession>
    <name>A0A9Q8LAX7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase-like 2</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cyclophilin-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Cyclophilin-like protein Cyp-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase isomerase-like 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_03043</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 22">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758372.1">
        <property type="nucleotide sequence ID" value="XM_047902191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAX7"/>
    <dbReference type="GeneID" id="71982921"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03043"/>
    <dbReference type="OMA" id="NFIKHCA"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 20" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="19">
        <location>
            <begin position="42"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="18">
        <location>
            <begin position="315"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="511"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO14006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="562" mass="61744" checksum="B5869C9C85A4F857" modified="2023-09-13" version="1">MGKGTDKLYITHSEWSSEDAFSASAGANARKSANAGAGANFKRLPFSFCAVSLQPFEHPVCTANGTIFDLTNILPWIKKHGTNPVDGQPLKSSGLIKLNFVKNEEGEYVDPVTFKVITDNSHLVALKTTGNVFSYDTVDRLNIKAKNWRDLVNDEEFKRSDIITLQDPQNIESRNLSHFKYIQDGTSTLTPEKDAERGAGINDQNLGSAGKIIKAKEAVAKARAEREKAANQASGSAEAQALANARKAHADVAKSSRTTKPLPYNAAQYTNGQAAASFTSTGLTPSTSTEHAIMSDEEYMLKPKRVKQKGYARMSTNLGSVNIELYPEYAPKAVWNFIQLSKRGYYNNVAFHRNIKNFMIQGGDPTGSGRGGQSCWGKSFTDELEGPLTHDGRGVLSMANKGKDTNTSQFFILYKAASHLNRKHTIFGRVVDGLDTLDRLEKVPVDDKSRPEQDCVIQDVAILIDPFEDFLKQRSEKEAEEARKEQLKMEGGAEDERTTWTGKRIRANGKVEDSGAASGVGKYLKTATPAEQDEVVEEWDEAEPPPTKKVKKGGGFGNFDAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB33</accession>
    <name>A0A9Q8LB33_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_02333</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758592.1">
        <property type="nucleotide sequence ID" value="XM_047901481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB33"/>
    <dbReference type="GeneID" id="71982211"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02333"/>
    <dbReference type="OMA" id="VRPCRYY"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="54"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO14226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="384" mass="41589" checksum="086228FC82B6B03E" modified="2023-09-13" version="1">MLARGLRAAPAARQCLKQIQRPAFVQYQARGYATPADEKVAQFKGQKGSDGKYTVSLIEGDGIGPEIAQSVKDIYNAANVPIKWEPVDVTPQLKDGKTVIPDSAIDSISRNLVALKGPLATPIGKGHVSLNLTLRRTFNLFANVRPCKSIAGYKTPYDNVDTVLIRENTEGEYSGIEHVVVDGVVQSIKLITKEASERVLRYAFQHAQDIGRKKVRVVHKATIMKMSDGLFLNLARDISKEYPDIEFDAEMLDNTCLKVVTDPTPYNDKVLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDECSIFEAVHGSAPDIAGKGLANPTALLLSSIMMLQHMGLTREASNIQHAIFKTLEEGKALTGDLGGKAKTHEYADAVIKNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBD6</accession>
    <name>A0A9Q8LBD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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    </dbReference>
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        <location>
            <begin position="7"/>
            <end position="26"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <sequence length="163" mass="17821" checksum="05372B77BCEBEFC1" modified="2023-09-13" version="1">MFCLRSWVLLLVCLINQSPLYILLFLSANYVLQRPCVYCSILLFVLVFSLFDFSADIFEPRWNENAFTTMSKTATSVLGGNATFTEAVLETASLALSAVNGTGGSIASATIDGLRQRLMAEAAPVVSATASSTMNGTNGFVWLRTLTDKFQFRIPCLDVVVRL</sequence>
</entry>
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        </submittedName>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        <text evidence="6">Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.</text>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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            <end position="107"/>
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            <end position="23"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03058"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="11905" checksum="8CAEDEE50DCB67F2" modified="2023-09-13" version="1">MATRRLASQEKTHLDQDETKSDGKSNISPAVPSSVIYKLLFFTMAMITFPIGSYFLTVNTIFRGNSTYAGGLAALIANFVLIGYVVVAFWDDQAEREDESSEKKKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCS3</accession>
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    <protein>
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        </submittedName>
    </protein>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040397921" evidence="1">
        <location>
            <begin position="18"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="19512" checksum="4E1D4BD6B46EAFA8" modified="2023-09-13" version="1">MRLLTTLIPILLPLSAAWRVEWTLLDGTRLWSTGTFVDSGSIDDTTNCMTVPWTTPMPIKAVEWWEYKDNTINATKPGWAYWHPFKDYFEGWGNPNVGSFRVYWAREGGRPPPSKAEREAAEAVEAAALATVAAAAAEGRNGVGIGNGTVVGNGSVVGNQTVVRKTERVRREVHVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCZ2</accession>
    <name>A0A9Q8LCZ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08777</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907925.1"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
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        <location>
            <begin position="169"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="33239" checksum="17FEE660955BF575" modified="2023-09-13" version="1">MAAMLPAGGSGRDGNHPYSYDEPIEDDLIDPDDATLDDLEDPASTHDRAPLTGNISNQQANQNHRAANNATGYLNNSIPGEDRRAPIDTIDESVWDTLRRDLLAVWEKMRQVLWPKYLLGGMMARGGGMGGEGENTGGAEGVMGYVRGIVGRWPDADQLLEGGMSDGLRDWDLWGPLLFCLLLSFLLSLNARDDQRSLVFSGVFATVWIGEAVVTLQIKLLGGNISFFQSVCIIGYTLFPMVIAALLSALRVPTIVRIPVYSVLGLWSLAAGISILGGSGVVKNRVSLAVYPLFVFYIGLDCLCFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD73</accession>
    <name>A0A9Q8LD73_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_08345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907493.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LD73"/>
    <dbReference type="GeneID" id="71988223"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08345"/>
    <dbReference type="OrthoDB" id="3598904at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="474" mass="52866" checksum="C48994700A521CA4" modified="2023-09-13" version="1">MQKGFDIIAESKSGGGNGVQIKQHLDQTYTLFNGFQGIDLSVQQRLHRSRQQASPTFVFRRLSHFPSFSEANDYLNDLERARLSIRRELLSQAGEALDVMELGTMDAAAALCMRHSLSRVIDLSPRPDILQNFQSLQSGYEQWYNAFCHADSDLGGDEDSVTLLRITFLTSRFNLASSRDTDERTSDIESAYLSNTGYAIALSTDVLAQVSLCGFKSRRTETRKRAMRLLVSANKLEGVYQSAVLAGFIRRPMDREEALARELTVTAPCENFTEHDIPAQARVADVVFAQVDYRPRCINMIATRYIMDDSGEPAIELTEDMFDIFDGHDISRRSLLVSLATPYPADFASTSASDMAGMPQQIDFTNGGSSAHLFRSLTTAVFLPHPADAEIPNATASQSTPLHNITNIVLNNGLKRQFKDYRSSPGPVDSVLRSRGNPSYVSYKAVRMYQDHLHGSCEGQPTTLKQQGWMMNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF19</accession>
    <name>A0A9Q8LF19_PASFU</name>
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        <submittedName>
            <fullName evidence="3">Tripeptidyl-peptidase sed1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LF19"/>
    <dbReference type="GeneID" id="71983972"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S53_propep"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
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    </dbReference>
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        <location>
            <begin position="11"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="23153" checksum="B4B4F6F24631C033" modified="2023-09-13" version="1">MSVTRSDLLSLKQWVRQGELHGSAVLPMGIGLKQPNLDNGHGHALLEELSPKLATLRHAVDAVHSWLKDAGIAAQRIGHSADKQWIQLDVKVEEAERLLKTKYYQFENAATGQSHVACDEYFPPEHVSKHVDYVTPGLNLLAGGKASNDKPLDGRKRDIEKRGLRQPELLDSNLRWKNSHRPFRTECDWLRAGELRQVHHTAMHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFN7</accession>
    <name>A0A9Q8LFN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase citE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760906.1">
        <property type="nucleotide sequence ID" value="XM_047904094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFN7"/>
    <dbReference type="GeneID" id="71984824"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04946"/>
    <dbReference type="OMA" id="NADYADQ"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="11597" checksum="E740AF7424649F4D" modified="2023-09-13" version="1">MGRLALLRFGDFLNADYADQALLSVGIHPGGVPTELAKGMPEGMHSVLIDEPGLAGDTIVWLTAQRRDWLAGRYVSVAWDMEELEGKRSKIEGEDLLKVTLDVGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFP4</accession>
    <name>A0A9Q8LFP4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760991.1">
        <property type="nucleotide sequence ID" value="XM_047904086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFP4"/>
    <dbReference type="GeneID" id="71984816"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04938"/>
    <dbReference type="OMA" id="AHSETWQ"/>
    <dbReference type="OrthoDB" id="5426872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="309"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="369"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="46059" checksum="11239F176F4FC48E" modified="2023-09-13" version="1">MSNKPFPPLVHHKTTYLQPADAAKSLAAYLEKSRKCAHLHPDAWLDPTGIRFGPKSGPNGGWAIHHLRRIEAGLRGESLAVESRDDLAAQLGEEVLKEQDPYAAEIEETNAGDDTRVDAAIDETQHKNENEKTRKKREKKERAKREREEREGGASTSAGSESSKKRKRAAETSDADSKAPGTGANTPYADSMTAHSETWQTQQEFAQDQDMLEGEMGDRGAPVTKQGGVPAPVVQHDQQGGVIVPKKALSAEKKAARKAAKKARRAEESAAGANTAAQADAASAAKKQSSSLGPAGEPLAPGAPTWRKQIHPFTEEEDATIIRLHANGVKFKLIAAQLDRNTLSVENRFHHHLSRGKITINKSADPQTKRYYFSKAEDDTIVEMRGNGMDFRKIAARLGRTESTVKHRYYRWLEPGASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFV4</accession>
    <name>A0A9Q8LFV4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760998.1">
        <property type="nucleotide sequence ID" value="XM_047903352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFV4"/>
    <dbReference type="GeneID" id="71984082"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04204"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="15955" checksum="11BF09CF29C94860" modified="2023-09-13" version="1">MLDNEVISAAQCSTRWTLLLSLSTSRHFGHSARTLQNIAAVHSQFSVHRSQPQQRPIASMAPKAVFVEFELEVRHPNSSVKPKYGKKAVNDTWAALNDAARRSITEKIVKAKNAATRAEEQTIVAVADDKRFSSARRRCTAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGK8</accession>
    <name>A0A9Q8LGK8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin NSP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Nuclear pore protein NSP1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoskeletal-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_04246</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nucleoporin NSP1/NUP62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761145.1">
        <property type="nucleotide sequence ID" value="XM_047903394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGK8"/>
    <dbReference type="GeneID" id="71984124"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04246"/>
    <dbReference type="OMA" id="EMMSKQV"/>
    <dbReference type="OrthoDB" id="344345at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000040">
        <property type="entry name" value="Nuclear pore glycoprotein p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026010">
        <property type="entry name" value="NSP1/NUP62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084:SF0">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="15">
        <location>
            <begin position="502"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="280"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="414"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00078941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO16779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="722" mass="70760" checksum="68819FF0BAD6157C" modified="2023-09-13" version="1">MADKKEPPKFSFGNTGGGGSLFGGTGTTGGGSLFGGAQTNTTPSTAAPGLSFGGANTPTNTAPSLFGSNANAGSSTPQGNKPGGLFGGATGGSFGASTTPAGEPKQTGNIFGSGGPPGANGGLFANKPDPTTAAKPLFGGASTGGGGLFGAKQDGTAAQQPSPIGTSQPASSGGGGLFGSNPTATSGASAGPSLFGASAAPAATPATPATTQGGLFGGQTNTPQPSLFGAKTGTTPAPAASGGENKNPTNSFGAQTTATPTNGLNLGGLGGAKTTGGLFGSASAQPAGQQTGSSQQQPASAPSLFANLGNNNTASSSGAPAATTATSGLFGNASSTAASSSAAPAATTSTSSMFANLGKKPETPQAPSEQPKTSNLFGAALGGQPPATGSSTTENPPKPSLFSSTSLGGGAAGSTGQTSQAPTASTSAAPTTGLFGTPTSKPPTATTTAPGTTNLFGGALGGTSASGATSGEANKGTQASSGLGGGGTGVAATAGAAPSGGSRLAHKSLDEILTMWSSSLTAHQKTFQNLAKRVGAWDRQLVENSSKISTLYGRCFQAERDCSEVERQLTNVEHNQSDIEHLLDKYEADVDQMMSQTGVSEDGISGVDAERERTYKTAENCSLRLTELNHSLSDMVEEINVTSNKLSSNKKTSDEGGNDDPLRQIVSILNRHLAQLQTIGTGAQALQEKVSLAQRDARNLNVNGLNGSNWVNDFGRSYLGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHD5</accession>
    <name>A0A9Q8LHD5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dimethylsulfonioproprionate lyase DddW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761876.1">
        <property type="nucleotide sequence ID" value="XM_047905075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHD5"/>
    <dbReference type="GeneID" id="71985805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05927"/>
    <dbReference type="OMA" id="AQAEIYY"/>
    <dbReference type="OrthoDB" id="445803at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF6">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17626" checksum="07262093418A422E" modified="2023-09-13" version="1">MGSIGTPAPAPRGFVLHKKQIDAMPLENFSNNSKRATGGWKQIFSSPDTPTDGLNLGIAHFPPKTATQESFEALHRHKQAEFYYILSGQALVKIDGVDHEVGPGAALFIPGDSEHGFWNTSESEELVFIWGFPCDGFRDVVYRFTGDKAEDAWSRKENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHR5</accession>
    <name>A0A9Q8LHR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="6">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NCS6</name>
        <name evidence="6" type="synonym">CTU1</name>
        <name evidence="10" type="ORF">CLAFUR5_06187</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHR5"/>
    <dbReference type="OMA" id="MGKCERC"/>
    <dbReference type="OrthoDB" id="198857at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000132">
        <property type="entry name" value="Cytoplasmic tRNA 2-thiolation protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032442">
        <property type="entry name" value="CTU1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16503">
        <property type="entry name" value="zn-ribbon_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="53"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Cytoplasmic tRNA 2-thiolation protein 1 C-terminal" evidence="9">
        <location>
            <begin position="398"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="320"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="46880" checksum="6EE9DF019B99875E" modified="2023-09-13" version="1">MPPSTCEICQSARAQILRPKNHARICSTCFIQMFEDEVAEAVTTADLFQPGEKVAIGASGGKDSTVLASVLKTLNDRHRWGLDLILLSVDEGITGYRDHSLEAVKRHAAQHDLPLKIVSYAELYGWSMDQVVAQVGKKGNCTYCGVFRRQALDRGAAMLGVGHVVTGHNADDVAETVLMNLLRGDLPRLSRATSIVTSTPSAKAIETTDGSVSFTNVKRSKPLMYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGSARTLIKNLERIRPESILDVVQSGIDMAKLVPDADGNCKGACSSGDAAAKGAEDQAAGGCGTALGGSSGGEMADMEKKLRQDDEAAENGTEVEIKVPAKAVTGQGHDRQSSASPGIPIRTKQEKKSNRKPTRDAPPLKQKLGQCERCGYLSSQAVCKACMLLEGLNKARPRTEIGVAEAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHZ4</accession>
    <name>A0A9Q8LHZ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Aspartic-type endopeptidase OPSB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_05837</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762091.1">
        <property type="nucleotide sequence ID" value="XM_047904985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHZ4"/>
    <dbReference type="GeneID" id="71985715"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05837"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF12">
        <property type="entry name" value="ASPARTIC PROTEINASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040211752" evidence="14">
        <location>
            <begin position="17"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="15">
        <location>
            <begin position="69"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="487"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="339"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO17725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="553" mass="57166" checksum="1A37EDEDF59A67C5" modified="2023-09-13" version="1">MRSTTLTPLLLASASALPELSISKRDKHNNGRTNVFARAVEALTFEKRQDGTVSTNVFNVLSWSAGGAYYTNITVGTPPQEQTVIIDTGSSDLYFDATSAATCNLPSTNANSCQGGTYDQTKSSSYKEVEASPAFNTSFGDGSSATGPYGSDVVGIGDIQLSPAQFGVAETVDSTTGYAIGLLGLGYTTNEAVTDPRNFYQNLPEVLKEAGVINSRLYSVYLNDARAYTGTVLFGGIDRSKYTGPLATVDLIPATYGNQVLNTVNQFITTITGLSTSVSGSNSDIFSGGAPGVETYSRNSGSLPVLLDTGSTAFSVSTGIYRAIVRQFSHVDRNGYVPCSYANSGDSISLEFDGKITIKVDASDFIVPLINSTTREPEPYNNDEDACLFLIQPSQIDGIGFGIAGDAVLRSMYVVFDLDNGQASIAQAAVNSTADPDIVTVAAGPTGVAAAVSGVSTPAPNSFSIAQGITTATQSYAASTVSPAVGQETGEGAIPAGAQVDGEDTGNGGGGGNGGKHSKNAAAGLMVPKMEWSGVYVVGIWMMCVMTGVGVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIM1</accession>
    <name>A0A9Q8LIM1_PASFU</name>
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        <submittedName>
            <fullName evidence="3">CTD kinase subunit gamma</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_06225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762429.1">
        <property type="nucleotide sequence ID" value="XM_047905373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIM1"/>
    <dbReference type="GeneID" id="71986103"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06225"/>
    <dbReference type="OMA" id="AREGMWA"/>
    <dbReference type="OrthoDB" id="21266at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070692">
        <property type="term" value="C:CTDK-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032786">
        <property type="term" value="P:positive regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="CTD kinase subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042326">
        <property type="entry name" value="Ctk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024637">
        <property type="entry name" value="Ctk3_C"/>
    </dbReference>
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        <property type="entry name" value="Ctk3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291:SF1">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12243">
        <property type="entry name" value="CTK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12350">
        <property type="entry name" value="CTK3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="28753" checksum="EFE9063FA4371B31" modified="2023-09-13" version="1">MADPFEVRMRFTSQLQHLNASTSSALKAANYALRYHEFSDDLHSCILEQLERNNMNNRANIMYFLPALCDTAKSQGDLQYVRMMERDILRIIDLVAPDDGSGAANVKVVRKVLQQLQGKSFLQPQTVTELEECIAGRDNVPGGQSSPTKDAAMPDAVRKTPISAGRDSGMFYNTGVRLDKRQIEQRIEEDRERHKRAREGMWAVQQNDQNLAQDVEFERTFDAGSDVDTDDYREAKEEAEERRKHLEFDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIP7</accession>
    <name>A0A9Q8LIP7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted isochorismatase effector Isc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIP7"/>
    <dbReference type="GeneID" id="71986347"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06469"/>
    <dbReference type="OrthoDB" id="269496at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="13"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="22491" checksum="E6A4ED24DC48B11C" modified="2023-09-13" version="1">MMTGPARRLVRPTLFVCDLQEKFRGAIYEFAKVVATTQKLLKASQALDIPVFATTQLRAKLGETCPELGLDGPDGVQTKVHADKSAFSMWTPEVQKAFKELGSEKRECVIVGIESHICVTQTTLDLLREGHKVYVIADGVSSCNPQEIPIALDRLRAEGAVVTSSESFLYECMGDAGIAQFKDMSKLVKEYSGKTKEGLQALSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIT8</accession>
    <name>A0A9Q8LIT8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIT8"/>
    <dbReference type="GeneID" id="71985484"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05606"/>
    <dbReference type="OrthoDB" id="3856067at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38782" checksum="DCD54C232DC867DD" modified="2023-09-13" version="1">MSSSPQVEYQDIVTFADSTEQFCTRYNSYNSPVSKTCSITFQGLESLRESNKALQETLAALDISRPQPSIISTPAQIVINAASSSCTRNKHVLDALFSTIPKDHREPKELLRVQQVGRDWRDTINGSGKLLRKMGLAPIDDVFYSSPLPTHGRGNPGGALPGMEYVPEGGESSWWTPYTGEYTTDLNPMSNQWHLQLMFDVPTPNLGSRCRAMLACHPPPEQISLVAECIEYERRYGGGRHEQKVELVDEKSNGRMTMGRRIETVIDVLKDSRCDLPTGHYVPCVRVRLSMTLVNDDPIILERHRRMDSAVEWSEGKKRRRRRSAAKGRADFDSGSDFEEVSSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ27</accession>
    <name>A0A9Q8LJ27_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762793.1">
        <property type="nucleotide sequence ID" value="XM_047905825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ27"/>
    <dbReference type="GeneID" id="71986555"/>
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    <dbReference type="OrthoDB" id="10488971at2759"/>
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        <property type="component" value="Chromosome 6"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040494959" evidence="1">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="91" mass="9762" checksum="3F92645D792A869A" modified="2023-09-13" version="1">MFSLKFVVAITGLATLVTALDDIKNCYCAHPIRIGKASDPPAIEAVCNTYGTLKKDSGGYTTRAIMIEINEPLFFSACTAQNGQNTANWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2L1</accession>
    <name>A0A9Q8P2L1_PASFU</name>
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        <submittedName>
            <fullName evidence="7">F-box/WD repeat-containing protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901421.1"/>
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    <dbReference type="GeneID" id="71982151"/>
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    <dbReference type="OMA" id="KQEWRKM"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
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        <location>
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            <end position="425"/>
        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
    </feature>
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        <location>
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            <end position="771"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
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        <location>
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            <end position="321"/>
        </location>
    </feature>
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        </location>
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        <location>
            <begin position="24"/>
            <end position="37"/>
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        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
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        <location>
            <begin position="112"/>
            <end position="135"/>
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            <end position="167"/>
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            <begin position="216"/>
            <end position="227"/>
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        <location>
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            <end position="290"/>
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        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    <sequence length="851" mass="95300" checksum="58AFF0FD2D8ACA3E" modified="2023-09-13" version="1">MQSPFEASAACHRQHFPETRPHTVHSSGSSSILTADTISEEEKSDGELTPRASEAGSSTFGQRRLSRDDTARDVHLPMMPPGQSRWVTRKKSPYSVDYMEAPFTKIQQPTEEQSRPRSEDQVHELAEGPHLERMRAKQRRKGPRASAHGVPMANETHDNTSADDAKDSGTLSRRWSKHYRKGVTNFQETMSKCQQLPAAIGGRSRRSSTPHRVEEASAPEAATSTTSVGPSANRLPISPSKRSARQTDERPRKYRPTWMHSSSDRKDTPAPANSLPHRAASTRNHQTPTILSAPGGDNARKAAAKCNNGSSALSWDQGNWEMPTQDDLQARRSRLGSLSSAADSGADLSAYGDSAASIRDRDGDIDMDTVSPQSLPPTMDITQRLPDEIALQIFEYLNVQDLIRAEMVNSKWREMTNNTSVWRAAFLRRYQRKILTDPAPVQVGGVGVGRPNKFKQEWRKMYKARVQLEDNWRAGAHDAGKAVYLSGHTDSVYCLQFDEEKIITGSRDRTIRVWDINTFQCLRVIGGPNVKPVLGPKVLRTVDYPSFHMATASVNGTAYGESIYHTPKEWHDASILCLQYDEEILVTGSSDSDLLVWDVKTYQPIKRLRKHSGGVLDVALDAKHIVSCSKDSRIIVWDRETYEPKGELTGHRGPVNAVQLRGHLLVSASGDGIARLWDLNQMKLIKEFSAKERGLAAVEFSEDMKYVLAGGNDNITYKFETDTGREVMQFTGHSQLVRSLWLDSANSRVVSGSYDLDLRVYDFENGQELWRGEEWTTSWMLAAKSDYRRIVATSQDGRILIVDFGIWKGAPTYVSRDGSSIENIDLLRGVENTNEIKFRNPFDRNRSIHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2M2</accession>
    <name>A0A9Q8P2M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="124"/>
            <end position="149"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="149" mass="16961" checksum="1AA209DD379DF045" modified="2023-09-13" version="1">MSNLLHTPTTIKSSRTPRKPKKSNLADVIELYATKRLTNLGLRNLQVHLWTIFLASFRSHIEQKLARHNGLDIFNKPEVTRHRFCTRVDEASLKSVVAAVADPENALEDGFRYAGSINVVRKKWEPYDPTPGEEEPEEPLERVTSKDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2N6</accession>
    <name>A0A9Q8P2N6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Psi-producing oxygenase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755496.1">
        <property type="nucleotide sequence ID" value="XM_047901366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2N6"/>
    <dbReference type="GeneID" id="71982096"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02218"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1172" mass="132296" checksum="35296EB697F750A4" modified="2023-09-13" version="1">MSSYIPHFGSEFSGQTQANGRVNGHDVPAPQASPQLQETKQGIWESIQQLGSLLKAVRAPLPTETGDGSELPQEDKANLMKDVENLYKDIRRQDINDLGALLETFKHAALKEPLDDRDYLMESLVAVASKMPDAKVQKKITNQFITTLWDDLEHPPQTLLSDEYKFRQPDGKNNNYKYPNIGRAGMPYARTVPPKTKQSATLPDPGILFDALMARKKPAGQAHPNGISSVLFYLASIIIHDVFRTSHEDYNVSLTSSYLDLAPLYGSNWKEQKRMRTFKNGKIKPDCFSESRLLSFPPGVGALLICFNRYHNYVVEQLAAINEDNRFSVDPRHPTVKRYAESDGKEPEEIDKRDDDLFQTARLITTNLYVNLILIDYVRTILNLNKTDDNWQLNPRIEIPDGPAVGTGNQSSAEFNLVYRWHSAVSEKDDLWTQQLFKEQFPKVKPADVGKPGGLYPFLGRLKEFADDLYNQEPEARPFPGLQAEQAKMQRQKDGPYKGSFRDEDVAELLTASIEDCANAMGPQQVPPVMKAVEMLGIMQARTWKCATLNEMRKHFDLKPYEKFSEVTDNVEVQEALKHLYDTPDQIELYPGLVIEDSKEARMPGSGLCPSYTASRGVLSDAVALVRGDRFYTTSCTPALLTNWGYQETQPDLSIDNGCLFYKLLLRALPNSYDPTSVYVHYPMTVPDEMHRVLRVLKKDHLYNFDKPKEIKHPVVVFSHDAAVKVANDQETFNVTWGPAMEFLMGPKAKNFMLAGDGPANAKSRKLMENAMYQREPSRGIPSGNEKWLKAVRDFYEQKTTELLKEKSYKLAGVNNVDIIRDVGNLAHVHFGAELFSIPLKTKKFPHGLFTEQQLYMIMAAVFICVFFDLDPPKSFPLRQKARAACQQLGKIMKLQVQSIATGGRLVEWLIDTIKPNDGPLGAYGVHMIAELCKADTDIDDLVWGNIMGTAGGMVANQGQLFGQALDYFFTEGRRYLPDINKLAKQDTPEADDTLMHYLMEGARLRGETGIFRVATKDVTIEDTTEILGKRTHNLKKGDKIMVDLKAAGRDPKYFPNPDTLDLTRPIDSYLMLGQGPHQCLGLPMTRVALTTMLKVIGRLDNLRPATVAIGKSSGEHCVKKVLKEFVPGDKEVVPEEWHYHVYLTEDWDLYFPFPTSLKINWDGPIPEARRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2W9</accession>
    <name>A0A9Q8P2W9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755570.1">
        <property type="nucleotide sequence ID" value="XM_047901384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2W9"/>
    <dbReference type="GeneID" id="71982114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02236"/>
    <dbReference type="OrthoDB" id="3438983at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="338" mass="36762" checksum="8835A1AE86521268" modified="2023-09-13" version="1">MVLNKVKIKTASVASSVGSTPTQATTTNPWTKNVAPALPKQPTVQSSPSPAPAPTPASTSQVPAWRRNASQAPGRSIAPSMLKSVLNGNASRLDPGLASAMGGLSLSSQKPAPPANYYDPSLGPEGEPLPDAWSGSACPSVNTIGGYNVSFRNASCVRHKRTVNDFQRGEIICLPFHVANLNPKNKLGQNFRLVKTCEGPAFSKRRILVVLYKHQQDLHCLPMYSFEGQGLAAKHQSLWPEYVQVKMQNATKFHQIGQYQPIVARTYDSSRPLMVESVVHLTGGVRVDSSEDISYVGRLTEESYLRLVALHDRRVAVAKKVPWESDRGRDGQGRFVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4I6</accession>
    <name>A0A9Q8P4I6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hetero-Diels-Alderase asR5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757148.1">
        <property type="nucleotide sequence ID" value="XM_047899968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4I6"/>
    <dbReference type="GeneID" id="71980698"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00820"/>
    <dbReference type="OMA" id="NGGMFLP"/>
    <dbReference type="OrthoDB" id="9977941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF3">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040500254" evidence="1">
        <location>
            <begin position="17"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="38422" checksum="A388A633A21AA5AC" modified="2023-09-13" version="1">MKSLLLLSVALPTAFATSNLDHSSRSDPSGDALLQKVYQFPNNTWVENLAVRSNGNILVSLISSPEVWQINPEAQSAELVFAFPHATSAMGFAEVTEDVFIVSIGNFSYVTGAEQQGSWSVWELDFGHAPLPVDEGRGYWRRPHYGYEQDIARVRKVLDIPEAVFLNGATALPGSAETGIVLIADSELGTIWRVNTRVETYRVAAQDPAFRPNASIPLQIGINGMHYHEGYVYSSNTFSTPLLARTPVSPSGYATGPVEVISESAEFPVNGGAAADDFAIGAKGDIWLASASSTLVKIAAHGEQEVVAGGADSKVLLGCTSAAFGRATKMKDILYISTNGGLGNPALGVVGGGLYSLDTARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5I2</accession>
    <name>A0A9Q8P5I2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758389.1">
        <property type="nucleotide sequence ID" value="XM_047901649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5I2"/>
    <dbReference type="GeneID" id="71982379"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02501"/>
    <dbReference type="OrthoDB" id="2373480at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="46767" checksum="9623F568F7380869" modified="2023-09-13" version="1">MGLFNFLLRLAAALQNFGSAILLPSQHPWYKPPPDIKSHKPGTVISSREIDTNLQGILPRGPTPNVHTAWQYMYRSTDSLGNPVADVATLLVPKNADPKKLLVFQSIYDSANADCGANTTSIDDVLFIAAALNKGWYVLGADYECLEGHVTAGVQSGYATLDGVRAALNAAPTNGLSKHARYALWGYSGGAIATEFAVELQPKYAPELNFAGAAIGGLTPSIETVLDTISETKFAGLAIAGVKGMSRAYPNFTRWLDHSPVPSKKAQFESIAKGCLSGASKAATNMDVFTFVKNGRAAMKEAIPRSVFEKGGTMGVHGVPTMPLFLYQGVMDQTSPIGETDKLFDKLCKHDGVNIQYQKDVVADHVSEALLGSLDAFQWLTARLEGKAIKNKGCKMNRVFLTDLDPGSLDSMDAHFQAVFAAFLGHGLGRPWWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P657</accession>
    <name>A0A9Q8P657_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759171.1">
        <property type="nucleotide sequence ID" value="XM_047907333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P657"/>
    <dbReference type="GeneID" id="71988063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08185"/>
    <dbReference type="OMA" id="GCAGKAD"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000213">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040528591" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="9">
        <location>
            <begin position="25"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="583" mass="62556" checksum="06FD4C6DE680CA36" modified="2023-09-13" version="1">MWAISLGFALVATVFAVPLDARQSAPSVVIRNGTVIGKTASGIESFSAIPYAQPPVGNLRLRPPQVLTQRFPGASFQATSPAAACPQFAFQVDNLDTNLQLAGLPSSIISDIIGEVINSPIGQTAINQEEDCLTITVQRPAGTTSSSELPVIFWIFGGGFEAGWSSMYDGTNFVTSSVNLGKPVIYVAVNYRVGGYGFLAGKQLAAEGSTNLGLRDQRLGLQWVADNIAAFGGDPDKVTIWGESAGAISVLDHTIINGGDHTYNGKPLFRAGIMNSGAVIPATDVSTPKAQAIYDKVVASSSCAGSTNSLSCLRALPYNDFQRAVTSVPGIFSYRSLDLSYLPRPDPGNNFFSQSPELAIAAGRFAKVPIIVGDQEDEGTLFGLVQSNITTNDQLVTYLATYFPTDPNAIENMRGLTAQYSNLIFAGQPDGSPFRTGALNSIYPQFKRIAAILGDITFTLTRRAYLDAITKQGVTAWSYLSTYAYGTPILGTFHATDVIFAFFTPSGTTIPGRSIHTYYVNFINDLNPNSASNTNALIRNWPTWTNATTQLLNFGLLGNSLTTDTFRQGAYDYLVPRFSQFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P697</accession>
    <name>A0A9Q8P697_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758963.1">
        <property type="nucleotide sequence ID" value="XM_047902504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P697"/>
    <dbReference type="GeneID" id="71983234"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03356"/>
    <dbReference type="OrthoDB" id="5314997at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28235" checksum="4E17CBFBFFD34124" modified="2023-09-13" version="1">MDKSILNRLPAELRLQIFEHVFPPGDLDVIFVWGRRTPFTTRWPRPGNSHLALLSTCHQLRTEAMPVLLAHTRLVVRTVILDRNTKLASITNAKWQDVDPPLEIIRSWAHMAPNVASKIIIYLGEWFTWSQRAPPEAVAELVRLTQSEVQGTKADLSIGIRGDSSAFCNEATRFEVVFPSTSSLPQAKFYVQEAMSGRERAIDPFFDRDRMFRDLRLARTKFERLFEILEEDAAEIEKGACKKISSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6L6</accession>
    <name>A0A9Q8P6L6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759529.1">
        <property type="nucleotide sequence ID" value="XM_047907022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6L6"/>
    <dbReference type="GeneID" id="71987752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07874"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="470" mass="52092" checksum="633A2701A44C126C" modified="2023-09-13" version="1">MDKKAEGHIEQVLETGSSLDTHNEKVQVDIEHAQQLAAAYMPGSPEEKALVRKLDWRLVPTCWTMYLLSNVDRSNIGHAKIGGLEDDSALTSTQYSVIVLVFFVSYLVYEVPRSHKDEDNMILNRVKPSYYLLLLGVLWGIVANHKHLVAMRFLLGIFEAGFAPGCTFYLSSWYKKYELTSRFAWLYTSVAVAGALSGLLAGVITDYMDGAAGIRGWRWLFILEGLASVLAAVVVFFILPDFPTSTKSKFLTEEERVLACNRLAIEGIGLTQGAHERIGEWQAFKMTCADWRTWCLCLLFVLGTGSQTMQYFVPSLVKTFGWEGNTAQCKLNFILWRDFTNVSTDHTIPSYAFAVICILSSCFLADRIKNIPLDLAGLSGFGFIFFIATTACSDGMTRYALAIFAFGTVYGCSPLVKTWISHVLGHPAEKRAIAIALINAIGNGSSIYGSFLWPSHDSPKYLIGFGTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M1</accession>
    <name>A0A9Q8P6M1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08386</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759651.1">
        <property type="nucleotide sequence ID" value="XM_047907534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M1"/>
    <dbReference type="GeneID" id="71988264"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08386"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03002">
        <property type="entry name" value="PDI_a_MPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040346494" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="515" mass="55295" checksum="E9E24E5E8BD79DC3" modified="2023-09-13" version="1">MVKSRLAAVAASLLLLQTANASLYSKSSPVLQVDGRSYDSLIAKSNHTAIVEFYAPWCGHCKSLQPAYEKAAKSLAGLAKVAAVNCDEETNKPFCGTMGVQGFPTLKIIKPGKKPGKPIVEDYHGPRAAKGIVDAVIDKIPNHVKKLKDADYAAWVAEGGPKAILFTEKGSVSALLKATAIDFLGVLGVAQIRDKETEAVEAFGVEKFPTLVLLPGDGKDPITYDGELKKDAIVKFLSQAASPNPDAAPKKEKPKSTDKAKASKSSSSFAKSSASHASEEAKTKAATQTEETIVNDPTDSPKPAVAAQKPIQLEPAKPIASLQDEVSLQQKCLNDKAGTCVLAILPEDEVPSEKTIQAVTSLSELHHKHEQAKRNLFPFYQVASVNTQGAAIRKQLGLSSSDVEVIATNGKRGWWRHYTGGELSLTKLEDWVDAIRMGDSPKKSIPDGLIVDASTLPAEVKVDTEAMKEALKGKLPEGMEMMMEEIDDEEYERLMNAGKEKAEAEAKAADDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P741</accession>
    <name>A0A9Q8P741_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759982.1">
        <property type="nucleotide sequence ID" value="XM_047907317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P741"/>
    <dbReference type="GeneID" id="71988047"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08169"/>
    <dbReference type="OrthoDB" id="5415055at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="601" mass="66629" checksum="2ACF4E32F02E2348" modified="2023-09-13" version="1">MYNAAHFTQITETERDGHHNLRIATEAARLAMSVDDWKAPELCPPHWRLPPKRSLRSKLKPATNVPSRILGRHNSRRTSRRPPIMRMKDSDDYITARAANPRTGLISPSVGTRTPCTPDSPGEALRLRTNDQTLPTPDFGSRTVKCRANQGRKIGNVSKQEAPPREHRRHSSRQGETTTPTTGRFDALDGPERRDSVLKDDQFVVHMPSAREPQPFMYPGYTPEQIEALKHYRQKTRRVSSEGYDQRLLRGSGQHSSKLDEGFTEDDLYALCPGVPGQPSFKPYRYEHTQTSPELSRITVRKRKTPRSDTNMTSNEPRRFVDKLEAKAATLFAPFASPKKTQHVKEPASTSREIPRTVPQHNACRATEQLPVKSIGSAPSPSAVVNPANVDHHHGEALKQRSGSGQPPICVPGSFEVADLSCLPRVKLVRPELAAVPRATLPTGRDKSRECSLSCQRDNNGQEKCAEIRDISSATVIHRRVSSYAEPADQHESGADILGGPKTTLSAEMLVDLLRLFLSSAKSLEMPKVAVIETLSSSEASTTEKMIALKQVLSLAAHALAICTTLAMLWKLGAAIMHLLEVLLWPLMVPLRILRWIGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P745</accession>
    <name>A0A9Q8P745_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08492</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759878.1">
        <property type="nucleotide sequence ID" value="XM_047907640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P745"/>
    <dbReference type="GeneID" id="71988370"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08492"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.30:FF:000003">
        <property type="entry name" value="Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="156"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="274"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO15512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="316" mass="35056" checksum="ED8A1509D0CDD1B2" modified="2023-09-13" version="1">MANLDAKQLFETGKQIAKAAEAGDPPSTILALLAPLENVKVTEDLLRQSKIGVAVTKLRQYKADPKVGEIATRLVNRWKQEVNLHKKKRPAAAEGSPAPSNKALNGAAANGRSSGTSSPVPQSKTEVKEGRKSTVDPEKRNTNTDNINHKLTGDAVRDGCLKLMYDGIAFKSEESPDAVLDVARKVEVAAFQHFKSETNQDYKAKMRSLFQNLKMKNNTLLRKDVFSMRIAPKDFVTMTAEDLKSEEKREQEEALQKENMRKAMTAIEEKAVSTTMTCGKCKQSRVAYSQAQTRSADEPLTTFCECTMCGHRWKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P768</accession>
    <name>A0A9Q8P768_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760145.1">
        <property type="nucleotide sequence ID" value="XM_047903541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P768"/>
    <dbReference type="GeneID" id="71984271"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04393"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="61225" checksum="AD78751948A77FAB" modified="2023-09-13" version="1">MFEAHLSDSTNPAEIEFQEPLLHIIELYRQKVSFENEKEERRDELNKMKIKTQATLPIGDSRHSMNLEAWLALKPPPEGKGSEGWMHDNTALTLIELEKPFGQPHIHCFFPTMLINKALDGSKDIVNYVDEPLQDVNESGGWQQSEKFGECFEVNFPAQTTVLVVWLNVNNHYYVGSIDLSSSTATLYNSWPSRPPPTASSGSKPQKEPTKLKAVVVLEQMMRALAVEYKLPNSSVQLGDCIKQNNDNDCGFLAWDNMRYLLQGSEPLVSTYDVQAHCIRLREEALEKLYRVFCNGLGVPAVFTDSEKSAPKTAIKTAPKTAPKSATKTATETAPKSAPKSQPKSQDAVEAAAPTKSLAIGDDPAAPKGSTISPTSQNPLEERVDYARLNKVYTIPPYTKEGFYNVGGVARPPIIFDPSSIPELDDPKLQTIIAQHRAKMSDVSKAKLTTEDKELLEEVAVVETKAPEHASGHDSDDETGNQEVEAMRAKLQRLQTSISMYPYRGMTDEEKVSAGLPLEPLPVTFEGTTYHPRAQDSSEGPLLISIARTSGLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7J5</accession>
    <name>A0A9Q8P7J5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NEDD8-conjugating enzyme UBC12</fullName>
            <ecNumber evidence="11">2.3.2.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NEDD8-conjugating enzyme Ubc12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">RUB1-conjugating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquitin carrier protein 12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_04528</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.34" evidence="11"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760328.1">
        <property type="nucleotide sequence ID" value="XM_047903676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7J5"/>
    <dbReference type="GeneID" id="71984406"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04528"/>
    <dbReference type="OMA" id="CQVDFPD"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061654">
        <property type="term" value="F:NEDD8 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 17" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="19">
        <location>
            <begin position="28"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="16">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO15962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20495" checksum="AB21229A7FEE7D6C" modified="2023-09-13" version="1">MLKIWSMKQQQQKNEAASGQTKKKKVTAAQLRVQKDLSELSLGSTMKTHFPNPDDILNFTLTLTPDEGLYKGGVFNFSFAISQNFPHEPPKVKCKEKIYHPNIDLEGNVCLNILREDWKPVLNLNAVIVGLQFLFLEPNASDPLNKDAANDLMSDRDRFKRNVRSAMAGGAVKGESFDRVMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8I5</accession>
    <name>A0A9Q8P8I5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="6">M1Pi</shortName>
            <shortName evidence="6">MTR-1-P isomerase</shortName>
            <ecNumber evidence="6">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRI1</name>
        <name evidence="7" type="ORF">CLAFUR5_04716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8I5"/>
    <dbReference type="OrthoDB" id="2461at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.420:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10470:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004326">
        <property type="entry name" value="PRK05720.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF1">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="390" mass="41243" checksum="294B5BD6B5CA4ED3" modified="2023-09-13" version="1">MVLEAIRYKPGSLYILNQLQLPHQEEYDEIKTAEDGWHAIKDMRTRGAPAIAIVAALSLAVELTHTKTSNNAEEVCAFIIEKLNYLVTSRPTAVNLADAAGKLKKITQTAAASSKNDGAAVSKAYIDAAAAMLTADVSDNKGIGHHGAAWILKNTSYSGPISVLTHCNTGSLATAGYGTALGVIRSLHSTGSLHHAFCTETRPYDQGSRLTAFELVHDKIPATLITDSMASALLRLKGGKDRIAAIVVGADRVAANGDTANKIGTYQLAITAKHHSVKFLVAAPRTTIDLNTPSGEAIIIEERPGVEMTMLKGPRFDGVNVDLSSVEQISIAAKGIDVWNPSFDVTPADLIDGIITEIGVFEKDGSGKFDLTAAMEAKNESVKPSTVGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8L3</accession>
    <name>A0A9Q8P8L3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761377.1">
        <property type="nucleotide sequence ID" value="XM_047903076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8L3"/>
    <dbReference type="GeneID" id="71983806"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03928"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14902" checksum="DAFF297909068FEA" modified="2023-09-13" version="1">MNAPRYIPRNSQENPNHIYALPADLTTNAGVVQRYNLKGPIEKRQKRSVRGLAKQYIYSGSESDSDSSDGGDCARDLWERPDGDLTLEELFERASLSAPRGALRARSWSVPTVQVLKKRTLEPRAWVWVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9C2</accession>
    <name>A0A9Q8P9C2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762263.1">
        <property type="nucleotide sequence ID" value="XM_047904859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9C2"/>
    <dbReference type="GeneID" id="71985589"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05711"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="13719" checksum="2F09C265DA6DCFB3" modified="2023-09-13" version="1">MGFMWLHDNYQQGKASPTLRWRLMVFWAWFVIISGMFLIIAGTYGSVADIIDSYVQRKWRFRSLDLRRQLRLDIKRRYTVRTALCATLGREIDDNVPMNGHEQRDIAALIISRPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9M8</accession>
    <name>A0A9Q8P9M8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase claM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06858</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762800.1">
        <property type="nucleotide sequence ID" value="XM_047906006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9M8"/>
    <dbReference type="GeneID" id="71986736"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06858"/>
    <dbReference type="OMA" id="VARHPCL"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="512" mass="57585" checksum="909328EC37E590F3" modified="2023-09-13" version="1">MALLSLANDGTALLAVAFGVFATLTSLVLYLFSKPAFPKNAPQYYNEKWPLLGAMHFFTNRWDFYRRGVASSKTGNFSFHAGNYPVVALSGEEPRKIFFENKNLAFGEGYGALLGGSPDVKVDNNPLAESAAGSSEFSHYFTKRLTAMLKGPVLKNGLPQLLKDARANIDKLANDPSGVTNPFDSIYRLVFHVTMRTVACNDVANSPELIEQCLHHFEAIEGTGTPLSIMYPWMPVPAKFKRLYAGAQLYRIFQKVVDERKRTGIKDDDALQFLIDQDDSITDILTFVLGSLFAGQLNSGINASFILCYLACNDYWMKRVRDEVNSVADRHCPDTDLPLKDRLMRVPIEAWEGEFPSIDLCLKDTIRLQMSGTAFRKNISNQDIPLGKSGEVIPAGAYVTLGVGDMHYSPEIYSNPEEWDPARYERGEDKNQTYSWVGWGVARHPCLGMRFAKLENNLIVALFLAYFDEIQLTDEHGRPMTKVPKCNWNNHTARKPDVQMRLKYRLRQDGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9Y2</accession>
    <name>A0A9Q8P9Y2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762956.1">
        <property type="nucleotide sequence ID" value="XM_047906263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9Y2"/>
    <dbReference type="GeneID" id="71986993"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07115"/>
    <dbReference type="OrthoDB" id="10388262at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="535" mass="60318" checksum="37765B18BC1AA48B" modified="2023-09-13" version="1">MLYPPSLLTNFDGDMAGTNAGSKTERLMQIIEEARGTVLKASTIIQIASKAGSIVTAVEDDPAIRLTLLQHSSAVYQQAAVLSTIAVLYYSVYTNENHRLGRLLELMISLHRDTVGVQSFNGQLQNVHQRVMQERGEDDGDTLVCQAGTVSQGIMAQTSHSTESATNEQVPVELYVKQRGRSQGRRDSPQLSGGTRLRKEDLRQMTYHRLEGSFQRLRTIREALFRDVVKDGDDLTQLRFDAINAVWLSPSFDCVVDGHRNSAHYQRLLDVLIDVPEPSKRHTYHCTPLDLATAMSKLSIDVGMMFLEDPKHIIWPLGDDTGNAHSVVVLCNKEGYRWRYTAVELLADGQQRRRQPPTFEQLLRPGLRSVQADFQGLVNRSVKGWKSFPFLKLPAEVRLQIYDRYLEAGDHCDRISTHVVSELRMEVPAPRGRCAFNSSELLRPEQSWMAWPGAANIQEVFITLPQMRGVCITIFPSGYRLSRLLHLSGSTKRYQVQIKAFEELVRIIIEDHTTPGMSLQDLAAVLDFGNSVFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC1</accession>
    <name>A0A9Q8PAC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_06705</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763146.1">
        <property type="nucleotide sequence ID" value="XM_047905853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAC1"/>
    <dbReference type="GeneID" id="71986583"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06705"/>
    <dbReference type="OrthoDB" id="20303at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001256">
        <property type="term" value="P:regulation of store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040192607" description="Store-operated calcium entry-associated regulatory factor" evidence="16">
        <location>
            <begin position="19"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="249"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="313"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="390"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO18780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="439" mass="47233" checksum="9C8D52C1A064E2D0" modified="2023-09-13" version="1">MHLSGLVALLALATSSLAYYSKQKDAVKLSSIKTLTLRDGALTSARRVEPIPQLTCIGGNAKGLYDVDVMRCTNAGSDYGAEDIQWTCKASLPPEFKLGSTDVICEGYENPDDPYILKGSCGVEYRLILTPQGEAKYHDRVNNKAWRSKNRSGDESSLGDGLATTLFWIIFVAIVCVILYSVFTGGNRNGGRRPGNGRRAGGNFWGGGDDNDDPPPPYTPRGEQAEESAGTWTPIRCLKVLEIVTRAAVNSTSPRSPSRRGNRSSLSDNSSSGQPKPKPSSRGSSSQQNEPWRPGFWSGTAAGTAAGYAAGAWNASRQARAQEARNAYARPGPSNYNAPSGYGSWGAGESNRHDSDMDQDLGHELSSSNASTSYRDPARESTPPSPPRSHPRDFTTRRTREPSRPYSATENRAPARSSSSPAPSSSRQESTGFGGTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBD7</accession>
    <name>A0A9Q8PBD7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763736.1">
        <property type="nucleotide sequence ID" value="XM_047906741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBD7"/>
    <dbReference type="GeneID" id="71987471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07593"/>
    <dbReference type="OrthoDB" id="204883at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008024">
        <property type="term" value="C:cyclin/CDK positive transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000440">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000270">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="633"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="572"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="942"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="360"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="942"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="991" mass="112136" checksum="1CD50981B2FB0623" modified="2023-09-13" version="1">MDGSSLDKPEQSWAEGDSRREQSRHRSRDTREEGSREAAAGRDTSKPSAAAATRPPHSSTYASTRSPSPDRRHHNHRDRASSRSRRRSRSPISRQDLSGRRRSRQAQDRASHQHQPSRRHAESPTSHKRRTSRSPSLSTSHHHHSKRHRSRSHDRHSSPSRRHGSSSRAARSARSPRPARDKDALADRRQTADQATPRRRRSRSEESRRHTDSQRERRPVPPDRYPRRGESTDRQRRRSRDRRYSRSPPAEKQIDRAYGDTRRRRDEAYPRGSRRSPARARESERGSRRATRSPIGSSVRVTSRDSVKRDPLSHRRRDNRSRERSTSRDSRRSRKGESEKDSEMYGRGNYGGYPHGQSPYHHNSYQQSGHSHNGSPYQPGYQQPPSQPGAAYYQPRPGNQYGGSPNYPTREPFPRPAQRGGVAARGGRAHFANLSWTPGDGVKGGHLVQPGDKPKDGTTSTTTPQLKSVIAPPDPEDDDNPFRPPADLRAEDESANKRRKIDTSSETAATPKTAEELAAQAEREKNKISFSIKGRASMASAEKTPIVSKSSKVETSPLLAKKLPATISPLVQSTVQSNMPKSSNYVGNTRVGPPRQPSPPRTQKKMVRKKRIKPKPQLSEEHAKSDSVYYRKTGNDSVVGSGTYGKVYKGVHVYTGGLVALKKIRMEGERDGFPVTAIREIKLLQSLNHVNVVPLLEVMVERNDCFMVFEYMSHDLTGLLNHPTFALSAGHKKDLAKQMFEGLDYLHKRGVLHRDIKAANILVSSSGVLKFADFGLARFYQKRQKQDYTNRVITIWYRSPELLLGETQYGPAVDIWSAACVLVEIFTRHAIFPGDGSEINQLDKIYQVLGTPSRSEWPGVSELQWYELLRPAHRSASTFKEKYQDKVSPEAFELLQAMFLYDPANRPTASDVLEHPYFTTEEPKPAQVVELADLEGDWHEFESKALRKEKERQERETRRRERDGEKRKAEDAAGGESKRPKTGEPAVPTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBE1</accession>
    <name>A0A9Q8PBE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763702.1">
        <property type="nucleotide sequence ID" value="XM_047905861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBE1"/>
    <dbReference type="GeneID" id="71986591"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06713"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="380" mass="42419" checksum="9F12DF78D4E1CAE8" modified="2023-09-13" version="1">MPSRRPHTKTRHGCNTCKARKVRCDEEKPVCRNCTRGNRSCSYPSQILAIPNSLATAHIDAQDQIFPVRDMELLHHYTAITYKMMSPEPDQHSIWQVYVPQMAFSYRFLLHGILSVTALHRRYDAEECQKETLMNLARYHQQHALTLYIPRLRSINQENCHALFAFSMLLGILCFGMLDDEGLGSRALVSRFLDCFDALMGATAVAYEAAHWLRQGVFRPIMEDIWPEVHDFAHLKEGAKEALEALIAQVGETCKSEPTSGSSTPVPPLGAPVGEEVGNGVAGGMMSRRQAYLASIYGLATVMYPAPGDRQASIVVAWPILAGAAFVQLLKRRDPLALVILGHYGLGKRLTEAIAEELDVAWQPLLAWPLRRVSEVITPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBU9</accession>
    <name>A0A9Q8PBU9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764015.1">
        <property type="nucleotide sequence ID" value="XM_047909466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBU9"/>
    <dbReference type="GeneID" id="71990196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10318"/>
    <dbReference type="OMA" id="CVRDNIN"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="134"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="670"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="692" mass="78404" checksum="FDC161426A69B637" modified="2023-09-13" version="1">MFECRACIRRAVRAIARDALDAQTIHRPLISAPRLAARRPRRRLATAAIPTQHDGDALGPLIESAISSHTPRHSARPKKEENALTPAEEKALRTEVLWLKDPMKLADHVHYTLRNNQRDKALNLCRIASKSQHCTVAWNHTIDWHVKQGRYTAAIDIFNEMKKRAQHPDSYTYMLLLRSFPQTRLDPGEQFPKHMCSKALNIYNSMNAENSTVQPSIMHTNAMLRVCGLAGDMDALWAVASQIPESGPRAADYITYSTLIGAIRHGATAQDGKGNIPARDYAQKMRKAVNEGRSIWQEVVTKWRGGEITIDEKLVLEMANLLLISRSMKDWDDVLSLVQQTTKIERLIPPVGSPERMTGHVPREAETAVVEDSDGWVDSVISSFKPVTGPTKDPENPRKSASMAWVQPGNKLLSVVLDACLKMRTPKAAQAYWDEFTSRQNVQPDLDNFHTMLRILNLNRSSKKAVEVVQQMHNSGVEARPITYRLGMSACQRDWKNTHIMENATALIDDMQQHLSYPDVKTLESYLALALQTRDSKKVVRAIDRMDPMVHLLRSRITYGTEGVYTSINAHIAEKESALRFIKTMIGTIDTLKNRSLVPEKDFAHWEARRSQLQGFVGRSANSVQDQRERWEKKHGEGESVGTSKKGPVRRVEPRKPWQESRPFRMGPHKWAEKQLRVFQERPMRGSDEGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCJ7</accession>
    <name>A0A9Q8PCJ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764293.1">
        <property type="nucleotide sequence ID" value="XM_047909231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCJ7"/>
    <dbReference type="GeneID" id="71989961"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10083"/>
    <dbReference type="OrthoDB" id="2446291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="280" mass="30746" checksum="884B46AA7F33B2BA" modified="2023-09-13" version="1">MSKLVKYMQSAILTFYQRSRPTAGQGSHHGYHDSVLSTPASHTREQPKYNSDDDGSSSMVSEPGSPQDISMSSDDDMNGDTFSQSPEDSFIMSRPRPSNSSPWAQRLQTNRVPTPIVPMRPGGSPYRIGPRQHVRQRHPQEFSSDHLDVPSPIDEDEVPTPPSAAEAAGSQLSMLTVSDVDMQESDDVPTVNVHPVRPLSRNTNLDMYESAVESEPMDSGPETIVVRKQRQRSGALSSGNSPVRAGPSQPPAPRKGFSMGFRADCEKCRLRVPGHMNHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCL7</accession>
    <name>A0A9Q8PCL7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764346.1">
        <property type="nucleotide sequence ID" value="XM_047909695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCL7"/>
    <dbReference type="GeneID" id="71990425"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10547"/>
    <dbReference type="OrthoDB" id="6154379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10068">
        <property type="entry name" value="BONE MARROW PROTEOGLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10068:SF14">
        <property type="entry name" value="CELL WALL ADHESIN EAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040156158" evidence="3">
        <location>
            <begin position="18"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="463" mass="51794" checksum="A27039F3840276EB" modified="2023-09-13" version="1">MRYSTFFVAAAVTSVYATAPPAYGGNAPAPYESPKAPVYPSTSTTCTEEYPEKPTPYAPKETYPAKETYPAKETYPAKETYPAHETYPAKETYPAHGTYPAHETYPAKETYPAKETYPAHETYPAKETYPAHETYPASSSTCTESYPAKETYPAHETYPAKQTYPAHETYPAKETYPAKETHPVVYTTVYHTKTQQEYPPTHPAQPPVYPNKPEQPKTPEVPYKPEQPKTPEVPYKPEQPKQPEHPQKPQQPKTPEVPYKPEQPKQPEHPQKPQQPKTPEVPYKPEQPKQPEHPQKPQQPKTPEVPYKPEQPKQPEHPQKPQQSYQPETPKSPEYPQKPEQPKTPSYPQKPEAPKSPEYPQKPEQPYKPEQPYKPAPSMPAYKPAPSMPAGSYKPAPSMPAYTKPSYPQGTGVYKPSYPTGGAYPTGGYKPKETVTPYTGGAATYAFSGFAAVVAGFAAFMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCM1</accession>
    <name>A0A9Q8PCM1_PASFU</name>
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        </submittedName>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCM1"/>
    <dbReference type="GeneID" id="71990020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10142"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="128" mass="14860" checksum="F0D3ED1228958750" modified="2023-09-13" version="1">MSLHHLVSNSRQKQYAQNMAGHLAREALPDLESPISRDDLKQLWHLSHVTKISSLFQRKRSTDSKLQHAYRDLQTKEKKSPNFLDIPAELQFQVLYTRWEPIKAHPIYITRIGMHGNNARSSTAEKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCY6</accession>
    <name>A0A9Q8PCY6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10575</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCY6"/>
    <dbReference type="GeneID" id="71990453"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10575"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="11533" checksum="0BC98AC062C1D68B" modified="2023-09-13" version="1">MLRWLRNFQVVAQAKGLWSYFSGGAEIAEKLDPINYGFGTPTSTAAPNNVGGSKAAEESEVVKKIKKERTSKTRSSVLPDNILNGSTQAEGSRDAAKPDNASFRLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDF8</accession>
    <name>A0A9Q8PDF8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nitrogen assimilation transcription factor nirA</fullName>
        </submittedName>
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    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10276</name>
    </gene>
    <organism evidence="10 11">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
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    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71990154"/>
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    <dbReference type="OrthoDB" id="2154091at2759"/>
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        <property type="component" value="Chromosome 7"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
    </feature>
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            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
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        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
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        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="839"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="849" mass="94388" checksum="4FE60D42B830648F" modified="2023-09-13" version="1">MTDVSPMVHGNSAAAPDITPEAGSSKRQKSRHRASTACATCRERRIRCVVPPGENQCVQCQRTSTHCIIKNDDERRRPISRAYMTTLTERVALLESMLKEQGTTPPPVVYPPKTTRGSLYADGEESPARVGLAQARLNANNEHVKSEGPSPTTDPSPGYATPQTGSIAGESHKSRSDKEGSAGTSFDDKKEGLVSRLLSTHGHLSSDQLSGRMRFYGGTVNCHVYSENVTDHAKADQDRLEQARRAEKCVRSLPLETHDYLMSMFWQHYNSVLHVVHEEAFHEDREHGRTQFYSGFLHVCILAMGIRSADKTRPDMQRLALPGRESQLHREAKYMLDLELERPGGIPSISALIILGDLEVGVGRDNVGWIYSGIAIRLCYDLGLQMDSRNAGLSQREVDIRRMTLWACVVYDRYWSLFLGRPLTMKSSDLEVYSLTDQFERLGTCMPAGAEKSLHTRIYEALIDLMEIAGKIVEHAELRTQHSQTSGPDQQAYFKMAALDRELHNWVSRLPSDLRYTDDNRANAPLSFYLLHQQYHTTLILLHRPFARYDDDAVSETDEVSALDSHFSQASRAICTQSAVATAQLFWHHRQKFDGRQIFCTGMQHAGTAGTALIAALAYIPDATDRNNNMQYLEVLHLALLDMAHNYVPAERMAAVLDAVMIELRGGPISASSTTIPARRGGPSIESDRGSVKRRQTEPAISQTIRSMPPPPAPLHSQHVIDLSQHHENLPRAQSQMPGMGDYVMVTPQSAALPWPNLQAGGQLIGQQTHALLPAPGWISHVGAEFSHIPHANDLAGLPNGDMSHLNFMPFPSEDDWTRWHDSSIIGASTDLDGSSPRGRLHSTFRHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDU6</accession>
    <name>A0A9Q8PDU6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765004.1">
        <property type="nucleotide sequence ID" value="XM_047910138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDU6"/>
    <dbReference type="GeneID" id="71990868"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10990"/>
    <dbReference type="OrthoDB" id="3650850at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="178" mass="20290" checksum="A06AC7B6EC0E3E84" modified="2023-09-13" version="1">MATLDDRIAALPQELQDIILEFTLDSLLDVPSSGIVTITLWQKPPVSLQISRALWTKFATRYYGGRTFKAAEVLGFVCIYWLEHLQPEHRAMIQGIEFHNGVVRHNFVAETRIRGLLQLWSEYGRRLRYPGEVAEKFVVCYTKVTRVSAGAVGEVRIPLSSSEQEAQAMIYHPWDKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEU4</accession>
    <name>A0A9Q8PEU4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765549.1">
        <property type="nucleotide sequence ID" value="XM_047910093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEU4"/>
    <dbReference type="GeneID" id="71990823"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10945"/>
    <dbReference type="OrthoDB" id="3644735at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="24141" checksum="B2D5065A98AADBF4" modified="2023-09-13" version="1">MYAVIETPELLENILYRLDAKTLLLSQRVNKQFQGTIGGSSLLQQALFFKLATANGERFGTDGINDFFTRRGTQLQKAEFTWYHHNSIPVHFAKSHGKPVNHRSYLDIHCAPRGFIDDQLHTEHAIAYVVEFCLLRPKKNISTGHESWRRMYVMQGGLYGAMEKKLVRRDFKVNGAMSGGIELMNTTRREELREGQMMTAAEMFDAVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFT1</accession>
    <name>A0A9Q8PFT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thiamine pathway transporter THI73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08997</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766062.1">
        <property type="nucleotide sequence ID" value="XM_047908145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFT1"/>
    <dbReference type="GeneID" id="71988875"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08997"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="62"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="39386" checksum="8BA723383FF0552D" modified="2023-09-13" version="1">MSNDTSSSQPIAVPDSSDQKGHAAGTIDDALIFLRKHGNEQSSQAQDTTHTRSLRRKIDLHVISFLTICYMLNFLDKVLLNYSQVMGLSLDLNLTGNNFSNAASAFFIADLVAVLPNIYLLQRLPTAHYLGFSLIAWGICTACHASLQNYGGLLTVRILSGAFESAVPPALILLSSQYYTRSEQAARFAYWYSGMGLGQILGGLISFAFQHVGSHAALAGWRIMFLVLGIVTIGVGGAVCWFVPNTPMRAWFLDEGEKVVLPRHVQENQTGIENVHFHAKQVWEAVLDFQVWVMFAIIVLQSVGGGVITTYSAMLIRGFEFTAKEAALLNMPAGLVNIVSALVCVGLDRAFWGIDGLLRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFT2</accession>
    <name>A0A9Q8PFT2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766175.1">
        <property type="nucleotide sequence ID" value="XM_047908173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFT2"/>
    <dbReference type="GeneID" id="71988903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09025"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34776">
        <property type="entry name" value="F17F16.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34776:SF1">
        <property type="entry name" value="F17F16.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="44796" checksum="374FA24709B58424" modified="2023-09-13" version="1">MAGTRSSANNTPEKAGTKRKATASSPEGKSKGRPAKGQKTLEETVAPSNDEDLIDADVEDEDMKEVEANTTATKEDEAPLKECAKDNTLDQVKADENEEGTTSKPEESKNDTNGNAEGTAVEEDKEREKAQPSNIMEKGIIYFFTRGRVGVEDPNSVSDLQRSFFVLRPLPPGGKLGEGAIQDVGNNRLIALPKKVWPKSGADKFMAFVEKAKASMDDLKETFFQGSTYSTKTTGTRHTPEVTSLGEGVYALVSSGEGRTTTHLAYQLTIPQELGDVQKDVGIAEKGSFVISMKNPEGGAPSYALPATAEYPKEILEEFGSLAWLPARPAHLDYDNAAFLLIGESFDDGKDKALEPKAEDQQKDDKNVPKEELEQLEKEDEHRIDALKGDDTIFEDLGISSKDYPKVPSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGC4</accession>
    <name>A0A9Q8PGC4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dehydrogenase citC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766356.1">
        <property type="nucleotide sequence ID" value="XM_047908848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGC4"/>
    <dbReference type="GeneID" id="71989578"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09700"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="32"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="617" mass="67291" checksum="0967E1EE1472FDAB" modified="2023-09-13" version="1">MIGSTNGSKSALCTVEEFTAETFDYIVIGGGTSGLVVAARLTENPNVKVGVLEAGKNLMDDPQISTPGLYPTLIGREKYDWCYQSELVPTAGNKTYSMPRGRCLGGSSAINYLMYVRGSRGDYNGWASLGNDGWDWDSMLPYFKKHQTLDPAENGEHPDKQFMPTGAKEKFHGSSGPIHTSFNDYYEPFEYDFCEAAYEVGGGERTLVDAWGGDHMGFYSSLAAVNRSDDPGKRSYSATGYLRPNLGRGNLKVLCEAHVSKVLLDGNTAKGVEFIYGRQKLQVKVSKEVILSGGVIASPQILELSGIGDPEVLKAAGVECVVQNDRVGANFQDHVLGGMLYDLKPGTQSLDSMHGAEYAAQQQALYEKTNNGPLGSPGMLMGFVSYASLVDKETLDNTIKEIRANSLAKTDFEKRQEDVIVKQLSDPTFANIQTFCIGCQLDVSKGESQIEFFGAPPEGQTRVSLLVCLEHPMSRGTVHITSSDPLKHPKIDPGYFRNPADAKIMSEGIKWMDKVAKKPVMAKSLADRVLPPQDASIETEEDRVEFVKKHISTQYHLIGTCTMGEVVDNQLKVKGVKNLRVIDASVFPGHVSGNIMSTTYAVAEKGADMIKADDGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH85</accession>
    <name>A0A9Q8PH85_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766836.1">
        <property type="nucleotide sequence ID" value="XM_047911601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH85"/>
    <dbReference type="GeneID" id="71992331"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12453"/>
    <dbReference type="OMA" id="FFCETRR"/>
    <dbReference type="OrthoDB" id="2687876at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO-type" evidence="9">
        <location>
            <begin position="138"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="23109" checksum="C6CDEA734F5AEC11" modified="2023-09-13" version="1">MLPPLPAGDWNDAYITRNDESGEPYFQKVVRTQIPGVESSWHAETFEYLSLKLGSKLRTNVYEAQLPGSSHTVVAKFARFSWEVGYLDKECAAHQWIEGKSIGPSFLGNISEEGRTIGFVLEHIAGAHHASPTDYAACKQVLSELHQLGIVHGDVNKHNFLAVDNRAVLIDFDGAYRTQDKQAFEKQMQSLEMQLAEASGRGGVSTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHK2</accession>
    <name>A0A9Q8PHK2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS-type transporter VdtG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766898.1">
        <property type="nucleotide sequence ID" value="XM_047911374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHK2"/>
    <dbReference type="GeneID" id="71992104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12226"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="176"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="630" mass="67149" checksum="7CDD29EF04EA585A" modified="2023-09-13" version="1">MPYDRDRRSHPFQLSLSTQTLAKLEGLIRARSHYYNELQLTAELERAKHESQTLSPTDPRPSFGFDSSEVSTVRAPSVAVTIASVDERIRSHDASSDRTITRDPFTTSDEIEIVPTNSRPTTIGDPALFEKHPSTTRMPASIPPMPEKGSSSSPPGSISPPGAPTQYPTGLHLYSLISALYLAGFLFALDRTILVNAIPTITAQFDSISDIGWYGSAYLFTFCCFQLLFGKIYAFYNGKWVFMTAVAIFLVGSAICGAATSSVMLIIGRAIAGLGSSGIFGGSVIITFFSVPLHLRPIYAGILAVVLLDQYIPLGAVTLGIVFFTLQLPPAKKAGTPWREQVWQMDPVGNACLMPAVICLLLALEWGGSTCAWSDGPVVTPLVLAGLLGLAFVGVQIWLGDNATVPPKLFKQRSIAASFVYTLGVTGSMMTLTYYLPVWFQAIKAASPTRSGVMMLAMAVPAGVAGVLSGIVISKLVGQLGLATSSFGGFGAGLGIQSVGLVAQTVLARMEAPQGISLNFFAQSLAGSVFLAIDQTVFMNGLHRRLDGMPGIDVDSLDATGASVRDQVNAQQLPKVLSAYNGSVTDTFIVATACACLAFVASCVVEWKDVRKEKDQIIRGPQTPPTAEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHN4</accession>
    <name>A0A9Q8PHN4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11787</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767195.1">
        <property type="nucleotide sequence ID" value="XM_047910935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHN4"/>
    <dbReference type="GeneID" id="71991665"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11787"/>
    <dbReference type="OMA" id="AQWYNGM"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="69"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="382"/>
        </location>
    </feature>
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        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO22829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="415" mass="46696" checksum="F7B0E589C5272A88" modified="2023-09-13" version="1">MKDPFPIAPPTALIELVKPIADPLGLPSLALHAHEVLFAFGLYIFIDTVVSPILSSRLCPGTYNKLNKRTRLNWDVHVVSFFQSVLISALSLYVIFYDEERAALRPRGRWEERIWEYTGVSGLCQSFALGYFMWDFYKCAWHVEIFGWGMLAHAISAFSVFALGYRPFIHFYAPIFLLYELSSPFLNIHWFCDKLELTGSIYQAINGVFLTGTFFACRLVWGNISSFWVFYDIFHAIQKGSTSITNTDTGAPKHYSADDLLTIYGDEQGQRLAFSGGYKVPIWLGLVYLASNLTLNSLNIFWFGKMIETIRKRFDPPLGTKSKGEEYSGYEPKEKVKKEKAYNTSAAQRLDPNASQPVTSSGKGSVKAARQRAEAAMDGAIASSEDINTQRVTLADGSKGVQVEGQRTLRTRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHS0</accession>
    <name>A0A9Q8PHS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767034.1">
        <property type="nucleotide sequence ID" value="XM_047911033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHS0"/>
    <dbReference type="GeneID" id="71991763"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11885"/>
    <dbReference type="OrthoDB" id="3556832at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="57254" checksum="316DD672805FBA52" modified="2023-09-13" version="1">MPSFSARGITATLSIAPLQATLSDTINLGDISQQEKRVKKAFDAGQKLRERPIGPIGPNDKAKSPGVLQFLGTDESTPFLMAEASERLPNAISREQPLPRSSPSSPRGAIPTSHSLAEMSASPALAIHPAQTGINLEQDPQALMLTVATRTRTHIKSLAPQRTVVKTPDLKIEVFLNGALMGSEYINPRRANVNISTNVDTRFSGMRIHRQIEKPWVYREAGQAIVASQTAQSRWDTISAALAEEAHDRGVDEDGSPSPSAAFLSALATVPLPEHVKDASHLAVIDIVISTGNGKKHGSESGFVLEPLRMESKRFKKAACQMPGETPAPNTLRSTSPGVLVAQRAGEPPKKKARHRSGRVDSRISPPVHDQDRADLALELGASPTGRLVKQIAPSLPVTPSARRRQNGLTQNGTIQSPIKIKINTALGTAKSWIKKPLPTSSDDYAAGGMTDGDPSSEPSDSLPVQAHTKTSRSAKGDPYTDEEALENFEPPELCKGSAVSFAGASMYRMVPRWRPGYFDEEEVVGGMRIVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIM6</accession>
    <name>A0A9Q8PIM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767473.1">
        <property type="nucleotide sequence ID" value="XM_047911442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIM6"/>
    <dbReference type="GeneID" id="71992172"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12294"/>
    <dbReference type="OMA" id="YYPINIV"/>
    <dbReference type="OrthoDB" id="4158609at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="8602" checksum="CAB25A84B15B6512" modified="2023-09-13" version="1">MSGLKDTGALSTADAHQNERSGSGDVGHKSKGTSLFSGMNEYKRDPNNAAGAARRESIQDQSARSGVLGNLWNSTFKGTSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIN0</accession>
    <name>A0A9Q8PIN0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molybdate transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767556.1">
        <property type="nucleotide sequence ID" value="XM_047911249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIN0"/>
    <dbReference type="GeneID" id="71991979"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12101"/>
    <dbReference type="OMA" id="GSMPVCH"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031563">
        <property type="entry name" value="MOT1/MOT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970:SF9">
        <property type="entry name" value="MOLYBDATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16983">
        <property type="entry name" value="MFS_MOT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="461" mass="48725" checksum="8A2CA6E97B445FCB" modified="2023-09-13" version="1">MASWRANLKAINEHNLKTLRKAPLAELSGSLGDLGTLLPLMIAMTLNGSINLGSTLVFSGLANVFTGMFFGIPLPVQPMKAIAAVAISQNFTKQETAAAGIVMGVAVFVLSATGLLKWLHRVVPIPVVKGIQVGAGLSLVISAGTTLIKPLGWIQPGWDNRLLAIVAFLFLVAAALAPRIPYALIVFAAGLITAGAVIPSSDTTGDFTAGIWHPSPFVPKGDAWRVGAIDAAIPQLPLTTLNSILAVTSLSASLFPTFPPTPTTTAVGFSVAIANLIGPWFGAMPICHGSGGLAGQCRFGARSGSSIIVLGLFKFILGLFVGEAIIPLLQRFPKSLLGIMVLAAGVELAKVGQHVGESRDLWEQAEEDAEDSRPARRSREATEQESKDRWMVMLITVAGCLAFKNDAVGFLAGLLWHWGIRAPELIQKFRAGRGSIQLEHSSEQGQTLLVRNEDAPEGRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ04</accession>
    <name>A0A9Q8PJ04_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GDP-mannose transporter GONST5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11964</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767648.1">
        <property type="nucleotide sequence ID" value="XM_047911112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ04"/>
    <dbReference type="GeneID" id="71991842"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11964"/>
    <dbReference type="OMA" id="YVTGEMA"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="67"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="364" mass="39562" checksum="4BA5708A4FC23525" modified="2023-09-13" version="1">MTDDSGRHKEEFELSDDASLKSGKYDSEDRSSSESSSVQDGLLKESGDVEAQQPAPAEHYVSTRMKLLFLGAYFFLNLFLTLSNKSVLGKARLPWLLTAAHASATSIGCFMMLGFGAIKLTDLGTRENLVLLAFSFLFTINIAISNVSLAMVSVPFHQIMRSTCPVVTILIYRVLYGRHYSTQTYLTMIPLIFGVGLSTAGDYYFTLAGFLMTGLGVILASVKTVATNRLMTGPLKLPALELLLRMSPLAAVQCVIYAFMTGEAEQFRNSYLRGDFSKTFGAALFVNAVTAFCLNIVGFQANKMAGALTITVCGNLKQALTIGLGIILFHVDVGITNAVGMLITIAGAVWYSKVELDNKRSKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJA3</accession>
    <name>A0A9Q8PJA3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767901.1">
        <property type="nucleotide sequence ID" value="XM_047911999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJA3"/>
    <dbReference type="GeneID" id="71992729"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12851"/>
    <dbReference type="OrthoDB" id="2831684at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="170" mass="18823" checksum="754C7B8BFC188E39" modified="2023-09-13" version="1">MNPHGRTSTGTLLQDQNITFASTTPPDQKAAATVETIARACYQSLNDRKFDVVDYPWTPHISPSFEMSNAQAMRLTTTSRAAMLENFKAIAAEHPNCHIEVESCSTVLHKYGKELKADVYVNTRGGAGPVYEEGLVRKTVTIFEFWLVEGVWVGYKGTAIDGMGEDRSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJS0</accession>
    <name>A0A9Q8PJS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768141.1">
        <property type="nucleotide sequence ID" value="XM_047912467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJS0"/>
    <dbReference type="GeneID" id="71993197"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13319"/>
    <dbReference type="OMA" id="HELVWKQ"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="26305" checksum="C1EBF7A1A521E963" modified="2023-09-13" version="1">MPSAAELRKLADQPLDPNIPQTYGFRGLQEQEQPANASQRPSEATSAPLNEDYEPHHDKSLQLSADRQHILDSILRLYSGSGTHERDATGAQDMRVYAKKAVYDDIASYCDTRYKIAGQWYGIPAVMKSSVTKAVEVVQSSEADPASNTPAAIAFKMKRDWTPRLMLGKTFEVNHFVTLSLEKAAEEDGEGPAERIKYHKDQWNEKDYEHDGYGKIMKTVNGDYATIGTRPPKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJY3</accession>
    <name>A0A9Q8PJY3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768187.1">
        <property type="nucleotide sequence ID" value="XM_047911837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJY3"/>
    <dbReference type="GeneID" id="71992567"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12689"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053245">
        <property type="entry name" value="MitoProcess-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563:SF1">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="299"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="363"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="67104" checksum="71D5F17077A33D5C" modified="2023-09-13" version="1">MIIFANMASKQAVSRTAAKAIPTGQRASSSRANFLGQQAAATRVATSTYPARAHRKQQQLARSVYAVAFAGALATFSQYYINNGSFLKQSHAEAPPKDDEENPLVFEQSRKKAGVSKEENRDLISSQHLQVKRSWESPGVYAWGSNTGRVVAPDSTDNVIKTPRRIKFFDNKLLRDIKLDRNFGAAIDEKGNLLQWGIGYAPDIKEPVTTLKGKNLISLSISKDRILGLAGNGKVYSIPVSQEDQQSGTKVSESSWIPFWNGRSSIAYRDLTPKDFGYGEKVTAIAGGLEHALMLSSKGRVFSAASASDSFPARGQLGVPGLTWTSRLEGAFDQPHELTTLRGFPVVKLACGDYHSLVLDKEGRVFAWGDNSSGQLGFDYNAESSIIDSPSLLATGKLYSASSQQPKITHIAAGGSNSYITVDATRMPSKKDDPNDPRVQMQIGRVTADTFAFGSGIQGNLANNRWTHVQSTPTKIPSLSGLFEYDETTNQTVPIRLSHLSVGQSHASAIMKNITYTAASATTSSDDTNWGADVVFWGGNEHYQLGTGKRNNVAQPVYIQPLDMDAEVKRAKKSTGGKEEHRFHITPRATATLGDGRKVSVEQRIECGRNVTAVYSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK54</accession>
    <name>A0A9Q8PK54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768500.1">
        <property type="nucleotide sequence ID" value="XM_047912097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK54"/>
    <dbReference type="GeneID" id="71992827"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12949"/>
    <dbReference type="OMA" id="WCTIPFL"/>
    <dbReference type="OrthoDB" id="3645743at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="26914" checksum="4AD29AAEFBF5C242" modified="2023-09-13" version="1">MAILAPWKGYLGLAMPIISFLILANAAIVMTLSIFNAATLDLHADNIDNQIHEHAPRVRAQLVFFWCTIPFLLVVASACETSALFTNNLKPLVCLVTSTTAIGIWVAQLALWQTCLSSSTAYDKGFCPVPKVWSEHYPGWNWASPQGAAWAVLPIFVCYMVQIGFAASVFSRQRRTSFRSSDLRGSWASKLEVEELRSEVRSTKVASVEHNLLEEELEGRRDNYQDVRLSANLGSRGYRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKQ5</accession>
    <name>A0A9Q8PKQ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_13467</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768581.1">
        <property type="nucleotide sequence ID" value="XM_047912615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKQ5"/>
    <dbReference type="GeneID" id="71993345"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13467"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
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    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="17">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
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        <location>
            <begin position="292"/>
            <end position="477"/>
        </location>
    </feature>
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        <location>
            <begin position="517"/>
            <end position="685"/>
        </location>
    </feature>
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        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
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        <location>
            <position position="462"/>
        </location>
    </feature>
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        <location>
            <position position="155"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="704" mass="79785" checksum="8FDD26200902EC6E" modified="2023-09-13" version="1">MADESSPPDWVRALKPAGPQGSEILKQERAASNVNVDQLTSFLFGKEALDRKRDVLKILQGEPIFEKSQDYFEGRFEKFERALGRAKKLRQLTVKHNWSQEESRVANDLISEPLPYGLHEGMYLKTLRDQGTPEQHEKFLKPAEAYQHIGCYAQTELGHGSNVRGLETLAIWNKEDQTFTIHSPHLTSSKWWIGSLGKTANHASVMAQLIIDGKPYGPHPFVVQIRDLKTHKLLPNVYAGDIGPKFGYNTMDNGFLLFNKVKIPHGNMLARYSAVDPKTNKYIKPSSPTLVYGTLTWVRSTIVLQSGSVLARGVTIATRYLAVRRQFQDRDAPEWQKGENQTLNYTMVQIRLLPLLATCFALHYTGKGMMALYEANQKKMSASKRSVGQEQTIRGAGPEETQSGSDLLADLHGTSCGLKSLCSHTAVEGLEMCRRAMGGHGYSAFSGVGHWFLDYAPTATWEGDNYMLTQQVARYLLKSARTVLKGNEPNNDTTEILAYYLKRQDVGAAFDILGKDEDIVAAYAWRSAYFTFEALKQRDELKQSWNSLLVQFWKLSRAHSQYLVVKNFYETIHSNEISQELDPETLALQHKLFRLYSLYTLESESSEFFTSSACTVAQIRLARTRAVMQLLEEIRPHAIRLVDSWDFPDWQLNSSLGRYDGKVYEDMFYRASELNPLNKVMADPYPDSAVLFKGRENPQLKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKW0</accession>
    <name>A0A9Q8PKW0_PASFU</name>
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        <name type="scientific">Passalora fulva</name>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="EMBL" id="UJO24287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="70" mass="7934" checksum="61294185D3A4DE3B" modified="2023-09-13" version="1">MCRHGKNFAFVYAQNMRDTQRCNQQQPRASDKRGGRLHNYRVTSLGTHDSALAAYESGSVARRVSLYKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLC2</accession>
    <name>A0A9Q8PLC2_PASFU</name>
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        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">Race5_Kim</strain>
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    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
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            <begin position="25"/>
            <end position="36"/>
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            <begin position="84"/>
            <end position="101"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00003401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="16431" checksum="60165AC45EE87411" modified="2023-09-13" version="1">MANPPHRQVRTAAGPGAASPASGSQTTLQTDSTPSATLRLRGASAEPSQPRRVVWAEDVIDNEGMGKKSSKVCCIYHKPHEPGDSDSEDSSSSDSGSDSEPDLSRAQKAGGKGRGRKHEHGDGGEHGKGKEKGNQRKPSPNAYERQPKYKGKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLC5</accession>
    <name>A0A9Q8PLC5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoporin GLE2</fullName>
        </submittedName>
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    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat rae1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768954.1">
        <property type="nucleotide sequence ID" value="XM_047913123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLC5"/>
    <dbReference type="GeneID" id="71993853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13975"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000190">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="117"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="39399" checksum="4CEA0171641F9326" modified="2023-09-13" version="1">MAGLFGTASSTSSASSNPTQGDLSGDRPVTSPPTDSISDIRFSPKSDHLAASSWDNKVRIYAINGGGESTPVVAFDHEAPALNCCWSGDGTKVFGAGADKAARIIDLNANGAAAQQVAAHDQPIRCVESFMHNGAPMLVTGSWDKTIKYWDLRTPNPVASIECRDRVYAMSMRNDNMLVVGTAERHTHVIDLRNPGQFYKTIQSPLKWQTRTVSCFIDGSGYAVGSIEGRCAIQYVEEKDSPSNFSFKCHRQTPPNDRNVSNVYAVNAISFHPQHGTFSTAGADGTFHFWDKDAKHRLKGYPEVGGTISSTDFNSTGTIFAYAVSYDWSKGYTGNRPDYANKIMLHPIVGDECKPRPKTGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMQ1</accession>
    <name>A0A9Q8PMQ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pathogenesis-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMQ1"/>
    <dbReference type="GeneID" id="71994043"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14165"/>
    <dbReference type="OMA" id="HVTNING"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040218502" evidence="1">
        <location>
            <begin position="16"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="46"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="23050" checksum="292958B804F66B1A" modified="2023-09-13" version="1">MLLPTLLALAASATAAVHSSHPHSHLHHRDHDASLAKPKKFGAEGFYKQQCLTHHNIHRQNHSALALTWSDALASTAQKIASTCKFEHDVEMDGGGYGQNIASGIGQENVSAVITELWYNNEIGEFGEQYGVGSPSEEKFELWGHFSQVVWKGSREVGCWTEHCPNGVELAEDTFDYTVCNYGGPGNVEGEYAENVGAPVGMTTESWSYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQI1</accession>
    <name>A0A9Q8UQI1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763154.1">
        <property type="nucleotide sequence ID" value="XM_047906113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQI1"/>
    <dbReference type="GeneID" id="71986843"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06965"/>
    <dbReference type="OrthoDB" id="10516586at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20791" checksum="3705CD83AA4F1E57" modified="2023-09-13" version="1">MAVNHEIPVSPPDSMAGITEPAIKPEATSDTTQDTNLDPSIASEKEIAPHLESISRGIINAINTRNFDATSSPWIHVANSIETNRDSGPKGSRTVTKADLLAVFSWLGTEFPDYRIEIDSVSVVVHKAFVWSRKGCTAEVFINAQATGGPGFPLGVQRKYVNVFEFKFGEGRWLAVRETLIDGMGDFMVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQR3</accession>
    <name>A0A9Q8UQR3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763349.1">
        <property type="nucleotide sequence ID" value="XM_047906016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQR3"/>
    <dbReference type="GeneID" id="71986746"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06868"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="351" mass="39368" checksum="B35F4718064D5BDA" modified="2023-09-13" version="1">MAHVNMLESECEASRLTTGPAHLLTVVLILYGAILISALAALAAHAVESAVDKALQVYDRNFKPQKMPKGFFRVSIIEMKRMYTVEFWFAVAVLGIFALCVVPNPFGPAHCGPLMDATLTYGLSLVEKCLGTMLRKVEEIPEMRVRVAQRLNALGEEMEVESEGRLARDEQQTGFATSSRRARPATLSNVPDTTSSYHDGCNESTVSQAEGAEFRAVKPDEEDVKERSQQEDKKDITSVWGRVEILKREAEDASSTQRHTVRAQLSTDARLRLQNHHKLMALRSELGLQLKDAVRHVRNFRSKQEDSVEESGTIEVQSQHIDPDGEARDLGWEVVEEGPEDENWDWLPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URP1</accession>
    <name>A0A9Q8URP1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764309.1">
        <property type="nucleotide sequence ID" value="XM_047909090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URP1"/>
    <dbReference type="GeneID" id="71989820"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09942"/>
    <dbReference type="OrthoDB" id="3650523at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040375642" description="BTB domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="508" mass="55929" checksum="B08F81FFF3DC0753" modified="2023-09-13" version="1">MFSTTLALTTLTIHTALALSPSCAPGGNFDLTKRTLQLPTGTTNNPDQIPSSRLQGCNGYQDPGHNYFFTESGDGALVMKVPGDPPNTNCVTTSGSKHCRTECRESSPSSWSTTASKNRMYVDLIGVSGSQVCVGQAFQADSGYSKPVAEIYYYDNGDIKVGVEKVKAGGSQMLYQVGNVQQGKRWRTSATMATDQEEIASDGDVILVVGEETTRLRVSSMMLSAASPVFKALLGPHFREGQQARSAADPVEIALPNNASEPVTWVCLLLHHKVALELEANKVTEKLFDFAVTVDKYDCSEALRLQSRALLSQHAEDRPKRLRSDAADVRIIETAYLLRDAKCFKQQTGRLITHLRGNSSMPQAIRRYIHMLPESVLAAIEWKRNAAVNSFLEDCMSIAQCYYDNAQYDYNGFQTDVSQAIDAKRYWPPFTQRSSTASLKKAVKVLRGFGVYYKTCGECASVQDYRSKLEFEDLSLVADRVEEDCEGLCLACVLSEDADLKVACTKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URR2</accession>
    <name>A0A9Q8URR2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764357.1">
        <property type="nucleotide sequence ID" value="XM_047909535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URR2"/>
    <dbReference type="GeneID" id="71990265"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10387"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="18620" checksum="88A83E69DF4EAF9A" modified="2023-09-13" version="1">MYPEAKFILTDRNSGAWLRSMQNSVFAHMDSWPMFFQSLYDFDHARPLRQLMRKWAELFCELNFDEVARQAYIAHVQHCLRVVPKERLLVMRLEEPLDWEDLCAFLGIPGPEQSIVCRSPEGIDKEVGQSTTNVEDPSTWLALGTVALTVLSGLLFLWMVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI2</accession>
    <name>A0A9Q8USI2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765166.1">
        <property type="nucleotide sequence ID" value="XM_047910355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USI2"/>
    <dbReference type="GeneID" id="71991085"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11207"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="23936" checksum="65FE12CB510BDF4A" modified="2023-09-13" version="1">MVQPQAATMPPAAEPAPKATLFTIPQELRDLIYEYTFADDHVNIPETFSRSDSKPKHAALLATCKQIHREASPYYFKLTTFYIDQSKASTAWYGGLSFANRRKIRHLRCITPYARDTVLAHDIFVHSAQEKAERTMESAGLNAHYALCRTAQAFIAARCPLRTRFSFNAVGVPVGQAGCPIKIRLDMWDGKQKWSRWTESPLFEQCPPWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT59</accession>
    <name>A0A9Q8UT59_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765930.1">
        <property type="nucleotide sequence ID" value="XM_047908897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT59"/>
    <dbReference type="GeneID" id="71989627"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09749"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="16350" checksum="16952CF34AF254D5" modified="2023-09-13" version="1">MRLLRVTDLAFQEVPSHEPFPKYAILSHTWMTPNSQEVTFQNLERRDTSGYEGKPGWRKIKGLIERARCDAIEYVWVDTCCIDQTDPTELTEAVNCMFQWYQSSSVCYVYLSDVELEADLDTVPGPQSTSFLAALEQALRGCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT94</accession>
    <name>A0A9Q8UT94_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09228</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765974.1">
        <property type="nucleotide sequence ID" value="XM_047908376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT94"/>
    <dbReference type="GeneID" id="71989106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09228"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057215">
        <property type="entry name" value="DUF7893"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF54">
        <property type="entry name" value="DNA METHYLTRANSFERASE DIM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25423">
        <property type="entry name" value="DUF7893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAH" evidence="10">
        <location>
            <begin position="434"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1166"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1171"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1233" mass="138689" checksum="4F4DDF4B092409FF" modified="2023-09-13" version="1">MTGKRRSEAITIEDSEDELAVSQPELSLKRPRRTLDEATSARELLTPSTPQSTRPGRQRQSTTSPSSALQDVDFLSESEVPERDVEPAKVIRREFAGVALSGPAYPRSAYHGWQTPSEPMLEALAITKLRTAFASKYAEVQEDEKPDYTFFRLDDFSIYRGDKSNNHDGELVSLHLLSRDFYGEFLFDGTLSVGDEKFYVQGVPFRILSVDGYGEVESTDLGSQLCIQSRIGGKGQQDIWYQLGRPAQEYKRFYQPFLWLARFTKHFVDYLLEHEKVSLMHFHGLFLEWLRDQYDEETTFREWLAIAGLEDFRGLVAANVGYLRKECYGVDPGKLLRHPLWGEVNPHRLAAIPEQPNLEPKTVVTPYAYECFSAMYFGDQLAKREVSTAVLRRVIKRKQRLRLTPRHIAQHESNAICSLLTPASMARDSPEPPLDVSAGDVVCVHPDLSTKWGADGSPWFVYVQQVRAHGDRTLLDVLWLYEPKDTTMGKAYYPFKNELFMSDNCSCGREALDLECAIEKLDVSWFPQDPYAEKGLFVRQKFRTIHQEDTYDFVALHNDDFVCKCEDRVPIFEECRSKYAIGDTVLVREWSSDRGEDRLQPAQIVHFDTAKRRIQLRRLDRRSEIEPESNAPPNELVLSPELYDKSCDKIIRKCHVRFFGDERDVVAPYDRGGLGDFYYIGFDEPETTISNTLPLPDESGELVYDAHDSLLPRINQGWHPKTQPRKGKLKGMGIFCGGGTFDRGLEEGGSVDFHYAVDWAEHALHSHRANVLKPETVKYFLGSVDDCLANAMKGNKNVAGPGQVELISAGSPCPGFSRLQMDQLSDKSRRNASMVASVVAYVDFYVPEYFVLENVVSMTSGMGRDKTENVFSQIIAALVGLGYQVQQFLMDAWSYGSSQQRSRVFIVASAPGLPPLNQPQHSHGHPPNAFQGRALGKSSNGLSFGIRKNCFAPFEHITPKQACSDLPNIDDAQVQLCLTFPDHRTAINEPAANRTRMAVVPTRPHGMGLMQAKLKGLLRGEPSEHCDQVGRVRSLPTSTMYARVYPKYLFPTIVTRLTVGDGINGRCLHWEQPRALTVMEARRAQGYLDHEVLIGTAVQQLSIVGNSVDRKVALMLGLLLRESWMGVDTAAAAGHDALDDRADFADLEDEDSGQDEEQDYAGFNAEEEMGESQSPAAGSSGNHQEVSRATDVEDMNIDNRSAKIALQLSAEEIEEVKRDHFRAIGRILDARAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTR5</accession>
    <name>A0A9Q8UTR5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766517.1">
        <property type="nucleotide sequence ID" value="XM_047908503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTR5"/>
    <dbReference type="GeneID" id="71989233"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09355"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="17789" checksum="9E9E75C4C2647E7D" modified="2023-09-13" version="1">MRSQGLLASTSHRSHGFSKKRQPFEPREDYFKDPDDWASPTYGMPELFHQCFGTRKDGNVLHYMTCIELNLRAWREDDLVMLESAFEKARSVVFVEKRTLSGKRLVGWCNSDGSVPGYWWYEKAGLQLLPCEGETEDNDRKMIDRLMDSWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTW3</accession>
    <name>A0A9Q8UTW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766563.1">
        <property type="nucleotide sequence ID" value="XM_047908789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTW3"/>
    <dbReference type="GeneID" id="71989519"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09641"/>
    <dbReference type="OrthoDB" id="3634224at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="49057" checksum="0195C8AF8756E2B0" modified="2023-09-13" version="1">MGRLEKLPVEIVDEICTSIDAPSFRHLRLVCRELAAKSHDAFIRQHVRVVHVNVDECGLQHLVDLSSWQNLAPLVQTLHLYPSTLDERCDRKLFTARFMSTPQGSRFRTTDHARAYLYRYGSKNMATSAKAMHEAMVARQERFLDRPDAALIMLARAIRQLPNITTLTVGSQERTERLHGSSGQVIMGGRHSFSKTNTKQALAIVLEVLSHLAIRDLRIGRPMDSIDTTVLQGNKKTKWALMAIQNSVQTLTVCLGPPKHDFDSEALSGFLSKAAKLENLTLIGHYDMYPVSPAMSSSTTMSMLKRLDLEKCFVDPGVFRRFVARHQETVRSIELRSVIMWTKEWHDVLDFLTSDDMELDSLVLEHIRACRSSGEFGCLVFEHAGRRGCSFCGQRHDDTAEPCRHVRVSAYNRDDFIQMRQKLLQSECRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV20</accession>
    <name>A0A9Q8UV20_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767748.1">
        <property type="nucleotide sequence ID" value="XM_047912138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV20"/>
    <dbReference type="GeneID" id="71992868"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12990"/>
    <dbReference type="OrthoDB" id="3650371at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="25054" checksum="BCEE52154BAFE8A3" modified="2023-09-13" version="1">MGSNQKETTSTTDAGPRTGFLDLPPEIRNAIYHLALNSHSALKIHYFSREKIFRVTLVWNPQHSLPWAVTLSTNLLRICRQVHNEATPILYGSNCFEIHGQDAQVFLRAIGSSKQFLRHIHYSWPYNKLHYKQAVSLLKYATRLQRLDLQRYGRTAQEHVGALRVLMQALHKSSGAAGRSESVVNILHFVPSLSTVDAEELAIEARMTKEVRSELQKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVC2</accession>
    <name>A0A9Q8UVC2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768182.1">
        <property type="nucleotide sequence ID" value="XM_047911828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVC2"/>
    <dbReference type="GeneID" id="71992558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12680"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="26229" checksum="67DE330FCD0B36F8" modified="2023-09-13" version="1">MPTFAADPCSCSRLAQNNINNTPSDSLHANTNMAFSMNDVLDPLGALLWPPPAKIPTEQAPGKHPNARPAGLLDLPAEIWSKIGHYAIDAELVYTLKDICSPDCLPFDQIEFNGIQWPHQPAITRTCRVLREELLPYFYQTKVTFTIQHASTSQEYIRGFLKGIGASNRQNIRYAWAEGKKRRPVGLSRKVVSHYVGDLPLNLVPVERDRYGTRFEKGELYLVRFSEDDDESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVR0</accession>
    <name>A0A9Q8UVR0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Non-reducing polyketide synthase PKS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12824</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768498.1">
        <property type="nucleotide sequence ID" value="XM_047911972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71992702"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12824"/>
    <dbReference type="OMA" id="YCRGDGC"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="369"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="1291"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1671"/>
            <end position="1745"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1808"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1291"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1454"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1744"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1748"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1758"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1779"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1796"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="1323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO24132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2185" mass="236378" checksum="2E05671AB8C33A1C" modified="2023-09-13" version="1">MSNVLLFGDQTAEQYPLLHRLCLRKDNALVSNFIERVALALREEVRSLARSQRNTIPDFLTVSNLVEAYYQKGDKVPMLESAFVTITQIGHYIGYFSEHQSELPAATNTRVLGLCTGLLAATAVVSAKTVEELVTLGVEFVRVAFRSGAAVETLRSVLGQAGQEKAPWSTIVTGTNEQVAKQALATFHKEQGIAQANQAYISAVSTMALTISGPPTTVERFFHESVLSQNNKVQIPVYGPYHAEHLFSEADCDKILSGNIARELRKRTPASLVHSASTGKPMVAENAYELAKLALGEMLQRPVRWDYLLEDVVSQMAASKFGAKVYAMGVSNIANSLVSALKAGGKNDVSVIDHTALEENKCYVGRTQNDKVAIVGMAGRYPSAANHEALWDLLMKGLDVHRKVPADRFDAEAHCDPSGKGKNKSHTPFGCFIDEPGLFDPRFFNMSPREAAQTDPMGRLALVTAYEALEMSGYVPNRTTSTKLHRIGTFYGQTSDDWREINAAENVDTYFITGGVRAFAPGRINYYFKFSGPSYSIDTACSSSLAAIQLACTSLWAGDCDTAIAGGLNVLTNPDIFSGLSKGQFLSKTGSCKTYDNAADGYCRGDSCGSVILKRYEDAIADKDNILGCILGAATNHSAEAVSITHPHAGAQEFLYKQVLANAGVDAHEISYVEMHGTGTQAGDGIEMTSVTNVFAPRHRQRRDDQPVFLGAIKANVGHAEAASGINSLHKVLLMMKNNKIPANVGVKGEMNKSFPADLKDRKVNISLKEVDWPRKTAAPRKVFLNNFSAAGGNTALLIEDGPVREAPKGVDPRGTLPITVTARSIASLKRNIANLQDYVKDNGSTALSSLSYTLTARRIQHNYRVAFPLSDITKAGDALKAQVKESYQPVPMAATKTAFCFTGQGSQYTGLGQKLYQDLKSFRDDIDQLDQLARIQGLPSFLELLDGTDVQTLSPVKVQLGMACIQVALANMWAAWGVTPTAVIGHSLGEYAALHVAGVISASDMVLLVGRRAELLVKDCTPHTHGMLAVKGSVEAIRQALGDKMTEVACVNGPEETVLCGSGDIVAAANDTLTQRGFKATKLNVPFAFHSAQVDPILDQFKKIASSVTFNKPAVPVLSPLSGETIREAGIIGPDYLARHARETVNFWTALTSGQKEKVFDEKTAWLEVGAHPVCSGMVKASIGATLAAPSLRRGEDAWKTIANSMCQLFSAGVYIDFNEYHREFNDAQEMYQLPTYAFDNKKYWLDYHNNWTLTKGEAPQTREVIVEKEVAAAAPAVEIPAKRLSTSCQKVISEEYSANQARVVVRSSLADSKLYPVVCGHMVNNAALCPSSLYADMALTVADYIWKETRPGTEAPGMNVCNMEVPKPLIAQIPQPAQGQHIELEANADLEQGTLKLNFRSVQPDGKKIQDHAHCTVKYEDKTAWADEWARYNFMVKAQMEMLTAKTMTGGAHKVQRGMAYKLFKALVNYDSKYRAMAEVVLDGANTEASATLDFPTKPDDGDFYCAPYHIDGSCHISGFIVNASDLLDSEQNVYVSHGWGAMKFSKPLIAGMRLRNYVRMLPQPNNISKGDVYIMQGDEIVAVCEGIKFQQIPRRVLNTFLPPNKGSAAQAAPAPVVRQTPVRAPVPAPIKLAAPAPIKRTVVPAAPTPVTATKKPKQRKVSAPKASGGLTDKVMKILAKETEVDVSELVDDAHFENLGVDSLLSLTISAIFREELDMEISPSLFADYPTVGEMKKYFAQLDPGSSSSSSSSAADTEEDSDDDSIPPTDVPTPFDPLSTPASSAPSAAPSDAGKPELDSPTRDSLAEVGDVSLARHVIAQEMGVDISEITDGAELAEMGMDSLMSLTILGELREKTGVDLPSTFLSTNPTILDIENALGMRPIKAKAPKASSAAPKASTKTDMNEVSARLAKINKTDISKYPAATSVLLQGNAKVATKKIFFLPDGSGSATSYVSIPNLGPDVAAYGLNCPFMKEPEQWQCGIEVSSLIYLAEIKRRQPKGPYILGGWSAGGVIAYAVSQALLAAGEKVEKLLLLDSPCPVNLDPLPARLHIFFNEIGLLGTGDPSKTPKWLLPHFSAAIRSLSDYEPKPTIGPCPTYAVWCTDGVAGNPGDPRPPPAEDEDPAPMKWLLNHRTDFASNGWDQLCGNNMKFGVMGGHHFSMMKEPWAADLGKLIREGLDWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVU5</accession>
    <name>A0A9Q8UVU5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T-complex protein 11-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768661.1">
        <property type="nucleotide sequence ID" value="XM_047912519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVU5"/>
    <dbReference type="GeneID" id="71993249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13371"/>
    <dbReference type="OMA" id="FHAWKTH"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF18">
        <property type="entry name" value="IQ CALMODULIN-BINDING MOTIF DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="154"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="962" mass="108092" checksum="8948BBD921600E9A" modified="2023-09-13" version="1">MSQSDEGNDAHDIPTRNWESELAESVPEEAEQQQTFFAPPAHIAARFYRNALTRRKSSAASSRRNSLSSAQSHTSSRSHRRGSTGCQSTYIAQHLRRASIIESRKARLADRAAHAEQVRLRAALAKATPRGNNQSEERAVAAQLAKEKYLAKVAAACAEEVARAKRIAEEVKDRKLAEETRLRLEMEERHAEAEKRRAEYQRNLQIRRARRAMSAEKKLAVLEEVDVLDEEAIIDEIVEVEGQVDEVAAKRIQRAWHLYQRRKPVVAFKQLYLSAHRAQNTVFEEMTALVADTQVIDATTAMLTHLGLQEPNDANASLNTRTFLSAYMICAHPVAVLLNKTGAQEQDLISKASDLISQFEASVERLAPWNDYTANPMQLETLSQSYTAYTSAFAAWRLQDSSVLVDGMVASFVELDAIWQTVKDDSRGEVASDYRQGIRDNQVMLLSRIRKLAGPDRADMLIKKAIRESRRKRPKQRPASEVRPRGVEAASSDSGPSEQVVDEALPTFAVGSGEINKLFTSMPSNRVLTHELAIDKHYKLEDRNGDLRHQLYRSICDSMKAGFEAGNGAVWTVSAAENVKEKLLRMLKPGNNMYTMISEALDLDNINQQCQRGVFSYSGFFNFMANVLPKLCAPFRDQEVKALTDYLKSDENGDELNTMIEKLFRLLRMVDVLSLDYTNFMIMNVAPQLIKEAPGYEQRMFAKDLESHVVTLIRTRRWWQESYTSLTAEADRRDPEGVRHPSDRPSPQKIYTHALVETAISQGELDKDAVPETLLLDLERLQHIRTKAIRVAVVGAILLTTKNMLKRDVRSQWKTEAGRLWQLLSTEPYSTSSLSEPFTAAKAFSVLETAHNMPPSTKSHIYSTISRFFSQAAAATSSGEKFTDPVLKVLFQRLKSHVLSRLSAETSADRVRAASSASEKLAACGMAEFTSQVAGIVEVLERVRVVDWEGHGGWYGKIVEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVZ0</accession>
    <name>A0A9Q8UVZ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768796.1">
        <property type="nucleotide sequence ID" value="XM_047912903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVZ0"/>
    <dbReference type="GeneID" id="71993633"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13755"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="40149" checksum="326F6F3173BC62B2" modified="2023-09-13" version="1">MPVANGQKVDIPSVGFGTWFSDEKQSAEECILTALQSGYRHLDSAWAPGIPREEIHVTSKVWLQFLAPENVELALDKVLQDSGMEYVDLFLAHHTVVFKNKGREALEKAEPSMYDQGGMGVLLDEKGLPKNGQEGSFVPTWLAMQELVKKGKARAIGVSNLGLQDVQELLPYSKEIPISCNQVEMHAWLPQNELLEFHKKHGIVTTAFGPFGGGSITGVRVIDDAEIQKLAERAGMGIGQMLQSWAVQRGTIPVGKSATPERMRSNLDVKRLAEWDGEAGGGEVAGHQSGLRCAVLRVMGRPVVGTQLWRGLRLSSSCEDYHTACVQVVVLRFFGAMQCVWCGGLRTPRLDRGRALEVGWVVMACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVZ8</accession>
    <name>A0A9Q8UVZ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA replication complex GINS protein PSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13592</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768885.1">
        <property type="nucleotide sequence ID" value="XM_047912740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVZ8"/>
    <dbReference type="GeneID" id="71993470"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13592"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21694">
        <property type="entry name" value="GINS_B_Psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1020:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.50:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056784">
        <property type="entry name" value="PSF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25005">
        <property type="entry name" value="PSF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028998">
        <property type="entry name" value="GINS_Psf2_subgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF2 N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="10">
        <location>
            <begin position="134"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="224"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="27647" checksum="152B58D3ADB5F363" modified="2023-09-13" version="1">MALPLPPGLTPNEVGFLCEMELVTITPRQRLESLELLGGPTERLNPPFPAQLPLWLALLLKRQNRANISPPSWLSVDALTNMLELETSDILAGSLAPGPTMSEATGVAMPSDPYLAQSSLEISAPFTRDSSTARAPADALPYHWLELSHLLLSHASDDFDDPDAVRRLVRDLREVRMSKLRKGYKVLDASGSLKINGVGGMEIAEVRGFVGGVIDGLRKINKSREEARREEMEEEGGGLGSSSYQDEDDDMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW76</accession>
    <name>A0A9Q8UW76_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            <authorList>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <sequence length="182" mass="21041" checksum="CF61602803AFA06F" modified="2023-09-13" version="1">MPLLQLPSETRTQIYSLVLMQHATIILPDVNILEPSLLQVTRQIRRETESISWSKNTFCISLRNTNSDPLVRLQLKLDRLRATYSIDPDIEVSSSHQVPHCANLMKWLERIHNGTVGLGYPEPKAVYLGADVHLVKEYTVYSIFETVYRHLQDPWEDLRGLVEVQCAALRQLEHRWAMGRVP</sequence>
</entry>
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        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
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</entry>
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    <accession>A0A9Q8UWQ4</accession>
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            <authorList>
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                <person name="Chen L.H."/>
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            <dbReference type="EMBL" id="UJO25137.1"/>
        </source>
    </evidence>
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    <sequence length="97" mass="11404" checksum="833FEC64396590B1" modified="2023-09-13" version="1">MQSYRTAVLTWQDYSAILTKCETEQRRNRLWLWLVAGVAALFALGSAMERCLGRHLFSGDHAKDEKVEEKRREVKEQETRNDTFEHDIFSRKKDSAI</sequence>
</entry>
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        <property type="entry name" value="ABCC_6TM_D2"/>
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    </dbReference>
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        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="520"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="906"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="953"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1055"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1139"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="323"/>
            <end position="585"/>
        </location>
    </feature>
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        <location>
            <begin position="641"/>
            <end position="868"/>
        </location>
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        <location>
            <begin position="917"/>
            <end position="1198"/>
        </location>
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            <end position="1470"/>
        </location>
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            <begin position="213"/>
            <end position="232"/>
        </location>
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        <location>
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            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO25403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1470" mass="159701" checksum="41FE49CFE386249C" modified="2023-09-13" version="1">MNNTKPCLGNADEHFGPGIATSCRGFDFTILFEDIFCVLLPSAIFVVAAGLRIATLLLHRPYGRQRGLVGQNEHRRRWPGVLFVALLAAYVALEGAAVGGALQKRERVGHAHVHVAASAVAFAAAVAVVLLWVVEKCICGCAKPSMLLGLYLCVRLLLRSVTVRTAWLVAASSADTSTATGTATAALAVHILLVAEEECAPLLLLRRPRGPRQDACSARSIRSTSSTRTSTARESRAGFLGRSLLTWLLPLLRTGFAPSRTLSVDDLSAASTAPSSFTTLDALQRSNSNSNRNRNRNRNNQRHAGLLKHALTCTARPALLARGPALTIALVQYFSRPHKPLDRGRALIAACFLLYSASAVANAWYRTLACRWTAAARALHTDLIMQKLARLPVDRVAEAQALTMMSSDVQRIATATSYAHELWAAPLEVALATYLLWRQLGLSSLATLAIALVCAGLSTTLGRRLVPTQRTWLEAAERRVAATRKFLASRKAVKMMGMDATVAATITDLRQQEFTASKPFRILTVSTVVVSFSTLSLAPIVTFGAYIVIHGAAFDAPKLFSSLVLISLLASPLVRLFQLVPLFAAALGCIARLEDFLCRDESHVHCAAAVHPPHSQPQLGTNQTNAEKSSRYTPSRPRDIVLVEDVHLRWDSHVLFAGINLRVPKGHNVAITGPVGAGKTTLLHLILGEIPPTMGSVIVDRSVPIGYCAQTPWLENQSAYDNVFQHSTLNDAWRTTIIDACAIRPLIDPKTSSAAGEPVGDRGARLSGGEKQRLALARAVAMRPSLLLLDDPLSAVDRRTLLHITNRLFGPRGVLRQLQTTVVQVANNDYAASFADEVFKLDGNGCLQTDYQYTKPECNIDDEQQWSADCQSTTVGQAEKATRYVATTASSGPGNTRVSDTQVYRLYLTSIGVWFFALFVICGMFFAVTMKFPNIWATWWVDSLTKQSASRSISLWMALYALLGCLPPIVLAVWLSLLMLKLVPMSGLEFHAQLLRTVLAATFRCASRCDFGDVMNRFNQDIGLIDSRLPLNLLNTISALFLCITQLFIVVTAAIYALGALPILLAVLSVLQMVYLRTSKQVRQLDIQSKAALHASIAELHEGLITIRAHKLQRAKHASFLDKLELSQRPFYTMYIIQVWLQLVLNMIVAGLSTAVVGLAVGMRTSTSASNIGLSMLNIVTLGQSLEELLEPWTQMETSLASIARIKSFELDTPQEHLSSNVLSVTSDWPKNGVLDIHGLWVTYSPESENPEWALQNVTLCIAAGQKVAICGRTGCGKSTLLLSILALLEPSQGAIVLDNIDVARVPQETLRTRIVTVPQEPYLHGDSVRAAVDAASDQALWDALQACGLVEKVQANGGVDSSLAALSLSTGEMQLLVLARRITHAGRAEGGLILLDESTSSIDRVAAHAMLKLVRTRLASKTVLSILHDLDAAMEFDRFIVLEGGMVSCDGSPADVLRESELFLSMRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWW9</accession>
    <name>A0A9Q8UWW9_PASFU</name>
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            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_14325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="43051" checksum="5A9C6D46059BC138" modified="2023-09-13" version="1">MPSERESTARAVIIAELASRPYWHRLWIVQECALATDLFILCGNSIAKASTLWHHKTVFNYTGEEAMWTVLGLKSGEMVSLSLQDAVIKFRDWPCFDPRDRIYDLAALIKWPSRRQIAIDYNTSSTDLCRQAMTYCNDSRGFDALLQTLGQRSEASLELAGIALCKSMQDFRTVCRLLSLTKTDDQDTIQAAMTFFRSIREIKDLEIVAQFKITIQERMKLAWEKLSLCSGGADVRTLVQTLDVAAAVDLAFIQAAMLRIERDWDRLKRAFLLSSSWVSDYDRLHLCTKLVHPAKSKHRWFITWDWPTESTATPMELYFTTEEFLLLATSSNIPGRPRYACNQNVRSFVKLEEAWVKDESFSEQQAMCDSIHENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXN4</accession>
    <name>A0A1P8YXN4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp50-1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 50-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp50-1</name>
        <name evidence="3" type="ORF">CLAFUR5_07035</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943100">
        <property type="protein sequence ID" value="AQA29271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXN4"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF1">
        <property type="entry name" value="HYDROPHOBIC SURFACE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573445" evidence="1">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="19571" checksum="6C188AA19986DC15" modified="2017-04-12" version="1">MLSLSNLLLFALGASSTAIVLPPYSSSATQIGNDIDSINDSITQLTDNIRNFHGPTVISDMRHLSDSLSAATQSIKTEDAVDDESAAFLVASVRDEVQPNAEDMLDALIKAEAQAKKGKIRQQILGWLQNLRNMMQNFGTGLAPKVPLDQRSELRKAMTAMLKDFDTAIKAYGGAVGVPPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YY68</accession>
    <name>A0A1P8YY68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04932</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">0WU</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943134">
        <property type="protein sequence ID" value="AQA29305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760993.1">
        <property type="nucleotide sequence ID" value="XM_047904080.1"/>
    </dbReference>
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    </evidence>
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    </evidence>
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    </evidence>
    <sequence length="454" mass="51727" checksum="FB05C4CF89D391B2" modified="2023-09-13" version="1">MTMLLRACLIVEPCTRPHHFCPGTLSRQSHLSEASCPVMGILRYHAQLVWFPTYQVDEGYVALLCRLNRSIRRRSVQFSVSLPAFPDGRKELSPQVSTMGLFSKAKPESPARVPGDEVVAMHYLDDQFHNKALLLDFISRFNDVLDPVKLKHSFERLLEIGDWRKLGGRIRLNEQGRLDWHIPQHYDDKRPGVLYHHVQHDQRIAVHPLASQLPRASSPPAIYQDPANFHGLAHPDHPISIEGFLYSDKPPIAMSIWSSKDATIVTMSWSHCLLDVIAHQSLFKAWTAVLAGREQDIPRLIGFKEDPVDTLAGRTPSHKDVLHDQLMSRLGFMIFVLYTVFEFVCFPKQEYRLISVPDWYIQKLKKQARDELAHERGSKEGPYLSDGDVLFAWWSQLTVSALPLSPTRTVYLGNVFDARGVFEHFFPAAGRPAVQQDRSDDTREPVAAENDRAS</sequence>
</entry>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
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    </dbReference>
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        <property type="term" value="P:regulation of nitrogen utilization"/>
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        <property type="entry name" value="DUF3295"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        <location>
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        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF11702"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11572.1"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="571" mass="62762" checksum="F9D216E299E93780" modified="2023-09-13" version="1">MPFRPEHSLLRVEVPLLHTVDTSSVEALMGMWSLFSKTSHAMEDGKRLENLSWRLWNRETFCCAPESQRPLSRSLPSQRRITPRTAATSGELSIPALSSSLDSASSSDDDDLDVDSTSHTITPRIPRARPGLRRNDSGESTRSRGREKHITPVDLEKIVTSIKKTNYLDPIDLPMPTPALPAVEPTSTNASQVLSRFDLDDASSNATPQTCTSQATLLESSASTVATDDSHNSHTSHHVGSQDSSSTEISGHSIVHGFTKPSSYRSHTNLAITQPTPILKTSPPLRQPVPEKRAKFILGSGSSAEDESSLESHMLRSALSESLKQSRGSLQNSKGKKTTSFKDEIAVARAAAVRHSPVFESDDEEDEVSESAIEDDDDSSDWEDSDEGSGPSSVNESKDLFQRVDSRPNLSSRRSLLTTMMHEPDRAKALQNAASKSQPALRRSRTSTPNGPSVAASPTENGFLQPKGQKSIPKPILTTTNTTQPLALSPRSTRRHMLSTELTESLRKNLLWERQHRSTGNLAAMKRRHTSNDVKNLKQHPEPVALSHKDPAKFNNDYFHQGLGEYHAKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6D8</accession>
    <name>A0A9Q8L6D8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6D8"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20716" checksum="D39E56BE3320EA0F" modified="2023-09-13" version="1">MPGPPDEVEVDEPVNLPSDDYAVRKIRGIRVEPNDVEGLPPIKYEVEWQGCPEWDTSWEPIQHIIFNRQAIEEYHARADGPEVNIGRLFESELFDGAYQWCIDHDIRPRPGTEAEHPRYVELLRLRRNSALFGGATVMVSPQSVQKVGTEEPQSAQKSSRSDSPAWCVSAKNHMPRNIHYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6H6</accession>
    <name>A0A9Q8L6H6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Meiotic expression up-regulated protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756121.1">
        <property type="nucleotide sequence ID" value="XM_047901031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6H6"/>
    <dbReference type="GeneID" id="71981761"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01883"/>
    <dbReference type="OMA" id="QWIYIGR"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF2">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="200"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="36825" checksum="E7AC944C4C1EDFB2" modified="2023-09-13" version="1">MNSKYESTAFEEWDDWCGPVDFDGISTHVPSTTVYDLPNDRRSQLPVHLPTESLGQHANFVSGAHGTYFESYSSYGYIPQHLSGQGMPWPASTTPPDAGLLSSPSASPTQGPYSGHVQNTGASPWSAYDQQHEQAHSLMNLEITRRASDPVEASPSWLGAHMEPGPRIPTSDNAIARTDPPPQQTSDEAIPRRQNPKFVNDQYTARWVRGDGTEREGWCGLCSSWHKLKDSAYWYHMHYTHGISYTTGKEFDKPVEWRPANSAAGAEALCGGCRQWIYIGRHDGGKWKTPYYRHAYRCQTKNKANGQSIRNRPKSTSPRRSAAKQVKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6R7</accession>
    <name>A0A9Q8L6R7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription factor SipA3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756220.1">
        <property type="nucleotide sequence ID" value="XM_047900583.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71981313"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01435"/>
    <dbReference type="OMA" id="TKVEWLW"/>
    <dbReference type="OrthoDB" id="10070851at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd07609">
        <property type="entry name" value="BAR_SIP3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13280">
        <property type="entry name" value="PH_SIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000079">
        <property type="entry name" value="Transcription factor SipA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000349">
        <property type="entry name" value="Transcription factor SipA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039463">
        <property type="entry name" value="Sip3/Lam1_BAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042067">
        <property type="entry name" value="Sip3_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="297"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="916"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="533"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="848"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="852"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1370" mass="152013" checksum="58234DB98311F252" modified="2023-09-13" version="1">MADSHLNLIPVGLKEAALDSPTFRATALHFADNIDAVERWLDGYVKAASKLVLEVSSLETAVNSFLSQSTPPTPISEAVLDHDYTLLAMRRYGEGAREFWNTTLRGIKRYDNAVVDPIKGWLNSDLRLFKEARRAMENAQKHFDGIISRYAAQGKMKESSSLREDAFQLHEARKVYLKSSMDFCVQAPQLRASLDKLIVRIFADQWKEMKNARESGATTFAKWSSEMERVRGWSREMENSERAFKHELSVARKQIEHNAEQMKRPSRELEDYSTSTVPYLGTGAAAATGTTKQAQERPEKQGWLFLRTVTGKPARTVWSRRWFFVKNGIFGWLVQGTRSGGVEESEKTGVLLCSVRPAFQEERRFCFEVKTKDQSVILQAETQQELTEWISAFEVAKRKALEDPGSTESISQTPGVDAAFAISPPVAPEFAAKVGDGHMPTGSEEVGLTVPERAGTDLPNRASFDVNPARRVTSLERDPEGIREGTREHAARIIQKLDLHKRSNTSTLQPSQAPTSGGIASLISASHNILPVGPGAPPSNATDSIKRNLTMPSSSLAPNTLANPPAATNLSHAAVVISGERGIGLGRADGSGMPSGILANLWGSSNWGHVNRIGEDLKPRKPSSNQNSPQLRAMSISQDDSIVMDGMHEPPKQIGPALAALGTSPGHRKNLSVGTESVAAAAKTATDDGADDYPNYYPLPLKAQNAQFRILFPSVPRSEKVVLVFRATWNPNDQQEFPGRVYVTEREIYFFSNHLGLVLITGVSLSSIKEVTAAPGRDCDFVYLHMKEGSRQDDPRRVTVKVFLEPLKLLQRRLNYLVKNADAEEPDNLQEMLKVLIKMEVEPPRRSSSVESWEDLADDAIDSPTGDPNTPQRRRERNIKANLRIDGNLYGEATRTGRDVQKFKLPGQAVVYAPQGMHASISREFNVSAKALFHVVFGDKSAVFQLLYANRWDDKIIQTPWSKPEGGHWIRKFTSQNHHSSPADSQVIDIFNDHLCYAVTNNKEPRRLPYATSFSLTTKFVITHSSKSRCKLAIYQNLIWHKPAPMAYIRRLIEKQAYNSLEADALDLTNVAMDQVAKLGNHSKTNKAIEIFGSVGQQTQAAQIDSKQVPQEVLPAVVSQAQPKQVTVLRLVANDLFAKALGITSMTFDIIVASLKGIIGICTAHTLLVAVLLISILYNGWYGFRDGLVWYHDRNAAKFMSKIGVVPNPAMTRAIYLHDMEELITPNVDNDTLSALSTDHDSVKTCRTTFGEQLVSSTSVDPGSANAAAARFHRSRESLARQRHDLLVALRVVNHVEKDIVLAEWEEWVRAEGKKCAKVEGMLRRRHKAQQDGKVRSDADLDAELGSEFAEYCRSCRLELGQLMNGTSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6S2</accession>
    <name>A0A9Q8L6S2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator-type transporter hxnZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756256.1">
        <property type="nucleotide sequence ID" value="XM_047900993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6S2"/>
    <dbReference type="GeneID" id="71981723"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01845"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="121"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="30023" checksum="BF94BF176AB19A2D" modified="2023-09-13" version="1">MPSMLRFSLEHLFAKHDASKFAEVLIPLEQAERHHSVAAENARRSSVGTNSEKHDNEKGDLTPPSVRSTPDGTPTLTLESLRDEINHDIAASGTNTSYDIKSKVVNKAIQDIGMGTYQWQLFTLAGFGWFADNLWLQGVALTLPSLSTEFGVDSNTVRYTTLSLFLGLCIGASFWGIASDIIGRKMAFNCTLFLAGAFGLAAAAGPNWIGTSALYACIGLGVGGNLPVDGALFLEFLPFASGNLLTLLSIWWPVGQLVSSLLAWAFIPNYPTHWGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L753</accession>
    <name>A0A9Q8L753_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756476.1">
        <property type="nucleotide sequence ID" value="XM_047900307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L753"/>
    <dbReference type="GeneID" id="71981037"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01159"/>
    <dbReference type="OMA" id="FIDETCE"/>
    <dbReference type="OrthoDB" id="548474at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="171" mass="18775" checksum="C7846F683D9CC1C2" modified="2023-09-13" version="1">MNWQPTDNPNLPADAFQVSPASQPISPALFAEAIQELPLDTLYAKAAELQNSISHLLDSNIQMKPFADEGDSDCKEAIEENDVVIKRFEERMELCKKEAQERGLGWSAHGSNTEEAPKANGHADGQVNGSASAAERDATRTRQTSGRLTDEEIRRQMDALVGEDEEDGVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L782</accession>
    <name>A0A9Q8L782_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pH-response regulator protein palC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756453.1">
        <property type="nucleotide sequence ID" value="XM_047901272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L782"/>
    <dbReference type="GeneID" id="71982002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02124"/>
    <dbReference type="OMA" id="PNDKEWM"/>
    <dbReference type="OrthoDB" id="10266451at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071467">
        <property type="term" value="P:cellular response to pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09245">
        <property type="entry name" value="BRO1_UmRIM23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037505">
        <property type="entry name" value="pH-resp_palC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="433"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="52246" checksum="1884C82701C9911C" modified="2023-09-13" version="1">MPFPFTLPTTSSVLLSDYFDSVTHPSLPLSATTRRSVLKDALKKHKRLPPQAQATNLSTVQDAVASYLPYLLALNTGSGYRDIGPEKLDVEVKKPLETEWRSTLSAALPGRENPRPKLVGLHHEAAFTLSTLAYVHSLLARAQMRMLFGGAVLSAEQRTGTIGAAMKHLLDAYAIHTYLLSLPSISAAKDAPVDIQPSTISALASLVLAEATIIVVAKDDPYTAAVADDRNEGNTDWMFKAPSIPKVRAHLFARICLAAGEHATNAHGLLARGSGGKIDEDLIKYASDLRRTARGKAARFLAIDSELSGKTGEGLAWLKGAKKELNLAADLEDGKRKGLRGLKQTWQERREDRKVSKGGEWGMDAGRFEEARVVEMLENKWDKENSTINVQLVPPFEPLLANMPSGREYHTPQPYVPPTLDQDVFVRMRAPPEPEEAVFRGEEEDSGDEEGYGGVVEPVGAFPGTGEEYGRSGTSNSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7J1</accession>
    <name>A0A9Q8L7J1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756701.1">
        <property type="nucleotide sequence ID" value="XM_047900722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7J1"/>
    <dbReference type="GeneID" id="71981452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01574"/>
    <dbReference type="OMA" id="HHFDKPD"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF108">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35723" checksum="6BCE33E10534D716" modified="2023-09-13" version="1">MSAFTEANRKAFDDLSATYSTKQWQIDISNQVADALRARKDWVGAQWNDPNVPPERRTQDVKLLDYACGTGAITKALGPYVTSISGIDISENMVAKYNEAASSSGLSPEQAHAVVGDLFAEAVPAELKSSEYYEFDIACIGLGFHHFEHPDVAIKRLAERLKAATGVLVIIDFLPFSTERDHGHAGESGEFQEMKHTIKHNGFTGDQMRDMYEEAGFVDFDIVALKQPAVMELKSGTVQRTLFISKGRKAPTAWQKLSSWVGGMQDWAAEGVRLKNDQHHWEPGYSQGRESAWDVWGQKEGTYAMVPEREEEKKKAWNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L895</accession>
    <name>A0A9Q8L895_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_01653</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757107.1">
        <property type="nucleotide sequence ID" value="XM_047900801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L895"/>
    <dbReference type="GeneID" id="71981531"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01653"/>
    <dbReference type="OMA" id="FPGRCAN"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000006">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000052">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="17">
        <location>
            <begin position="304"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO12741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="607" mass="69152" checksum="0F97FF88694EA6D1" modified="2023-09-13" version="1">MPTIAVDKAHLYEALGREYTTEEFDQLCFDFGIELDEDTTDQKRPVVDGVQERPQLKIEIPANRYDMLCFEGIAMNLKVYLGQQQMPKYALVPPANGEILTVNVDPATEKVRPYFSCAILRNIKFTKERYESFIALQDKLHSNLARNRTLVAIGTHDLDTLEGPFSYEALAPDQINFAPLNQTKSMRADEMMEFFEKDKHLSKFLPIIRSKDPEQRKNDLYPIIYDKNRTILSMPPIINSNHSKITLDTKNVFIDITATDKTKVEIVNHILVAMFSTYCEKPFTIEPVNIVSEHNKQTRQTPNLKPVPFKASTNFINSVCGLDLSREEWSEKLAKMCHYVKPSESDPDKLDVDVPVTRADVLHEADIMEDAAVAYGFNKLPRNFPNQNSSVAAGLPINKLADIVRLEAAMAGWSEVMPLILCSKDENYDWLNHPFAKEGGNAVQLENPKTAEYQIVRTSLVPGLLKTIRENRKHAVPMKIFEVADVCFKDDKLERRSRNERHFAAAWYGKTSGFEQVHGLLDRVMLMLRSTFITREDGMKNDKLQGYFIEEVDDPTYLAGHSAAIYLQLAGKPTRIGTFGILHPKVLKRFELPFPTSALELNLEVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8B6</accession>
    <name>A0A9Q8L8B6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757008.1">
        <property type="nucleotide sequence ID" value="XM_047899657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8B6"/>
    <dbReference type="GeneID" id="71980387"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00509"/>
    <dbReference type="OMA" id="HGGAIPM"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="83"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="18216" checksum="45351E33B4FA89CA" modified="2023-09-13" version="1">MAPSKIPGQDGTLTQPQATKLMSFFIKSHAASIPPTNFDRAVYDNLEVLSCTLLEPRITAKSLIRIKVPPNYSNQQEGKLPRTTHGGAIPMFFDLPTSITIVACNFSGWESTGMTRRLDVTYLKPPVEGDDLILESEVLSIGRRLATIRGVLKRERGWGCVGDLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8G8</accession>
    <name>A0A9Q8L8G8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exocyst complex component SEC10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757096.1">
        <property type="nucleotide sequence ID" value="XM_047899280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8G8"/>
    <dbReference type="GeneID" id="71980010"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00132"/>
    <dbReference type="OMA" id="PLCKHHY"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="7">
        <location>
            <begin position="80"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="6">
        <location>
            <begin position="208"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="883" mass="98216" checksum="931361DF78E80930" modified="2023-09-13" version="1">MARVGSPDTASILSGHSTSRPGTLQPVRGIHNQVFTLESFSSKDFIVKDFVESLSEISGPGRRSAPTSGPNAQASQAFDPKPLIRTFEHALSRLKTLSGDLQERENELTNGVRKAEAQHNANIKGRERELERAIGSFHRLESALDGDGDEGGNAAMRIGERLEELDRQRQRAQDAKFILQCWLDVSERGDLSSLDDVRKMGGGEGKVRCAHIARQLLKISQRLDGGADRPPKTNGVHFGNGVNGSNNDETDSPHGGLQRNKGGKQPREIIEKFLEMLEKDLLKSFDEFYRRQNFGGMQECAVALQDFGDGNSVISLFVNQHQFFIDRSQLVTDELTMDDTLDRLADPDTEPPGVEPSLQSLVDEVRVVVQEESFIIKRAFPYYEEVLARFVQRVFQQSIQQRLEMVLEKADSISTLAFLRSLQASRSYIAALVEDFKSHGLTDHPEPVSSTTASVLDQQLDELFVPYFTGTSYIEREKRNLGELFEGLLFKFTLYHSRRRNVKTQTHTYLGAISARSKEFISSARDAYMERLDSADLQARQKAMLLRIAGLHNAKDQASANEVDVTDEDGQLSLPSTKRMLKWLAEGVGRGLELAGGGSETPKEIRELLGLLISYMGEVYLETALNAAIDSATAAESNTKTEPDLSYITDLRSAVSVLHLMLTTIKMLLLPLAASNLTIRRDLEKQTSNFVDRMECKVDTVLQKTIDAALAWVAKLLSNQKKTDFKPKDDHTLQLDQLQTSTCQTIFTFLGRLHSCAKIAISGRVLESFSLELAIGLRSLLLQHFKSYQVSLTGALVVSKDITKYIELLRSWELPSSFDPSLEVMTEIANLFVIGPEALRDRLRNFGTGAGGLQGVEKADLRPYVMRREDSNSVGVQAVLNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8M6</accession>
    <name>A0A9Q8L8M6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-splicing factor dre4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757239.1">
        <property type="nucleotide sequence ID" value="XM_047899839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8M6"/>
    <dbReference type="GeneID" id="71980569"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00691"/>
    <dbReference type="OMA" id="MLKSTYT"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045148">
        <property type="entry name" value="TCRG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377">
        <property type="entry name" value="TRANSCRIPTION ELONGATION REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377:SF3">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="322"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="587" mass="67845" checksum="431234C267E9C174" modified="2023-09-13" version="1">MESPNKRQRLSSPTLATQDDFVAFGADDGDFGTNVENAEEATALHAPSGPKVDRERPQRTGHGRPDLDVRSDPRHARDRPKSKHVLPGHEPWILVRTKYRRRFVHDTQTKESLWWIPKDVMPGVVEFETWEKEQKEKNANAKWAEQQLKDMRDNSKATDVNQTADEEGRSRRRRSESLQREDEEAMMAELAAQAERYEEQDVKETVKAIDNLDERKLEAGLESDSEYEVVEVTDDEDEEAGAAGDREDQAESGQALVNHDVAAPSEAVDQQEGPVEFGEDDIAYQLAAMGEEYGLDPGEYGEDYDQEWEDGAEGLALNEEDASNLFRDLLDDYRISPYTPLDRVIADESEGSILNDDRYTVLPNMRARKEVFDAWARDKAAQIKQERAAMEKRDPRIPYLAFLHEKATPKLYWPEFKRKYKKQPEMTDRKLNDKDREKLYRDHINRLKLPESTRKADLQALLKSTPLKALNRDIRLDSLPQNLLSHLHFISLPSNTRDSIVESHIKRLPPAPGDDDMTDEQQAEEGKRREERKRREKAMADRERQVDEERRRAEKDEVRARRNLQDEERELQRAMAVPNRGLKNALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9V5</accession>
    <name>A0A9Q8L9V5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_03872</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757962.1">
        <property type="nucleotide sequence ID" value="XM_047903020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9V5"/>
    <dbReference type="GeneID" id="71983750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03872"/>
    <dbReference type="OMA" id="ASCAEYI"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF73">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="30"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="175"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="35"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="145"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO13596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="344" mass="36285" checksum="5993D3D247709C09" modified="2023-09-13" version="1">MFAARKVSQSVLGGAFQRRAFSATAADLSKVVVLGAGGGIGQPLSLLLKLNPRVTELALYDIKGGPGVAADVGHINMKSTVTGYEPTPEGLAACLKGAEIVVIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAQHSPDANMLIISNPVNSTVPITAEVFKKAGVYNPKKLFGVTTLDVVRASRFISQIKNTDPANENIVVVGGHSGETIVPLLSQSGHDLQGAERDEYVRRVQFGGDEVVKAKDGAGSATLSMAMAGARFTESLLKAAQGQKGVVEQTFVDSPLYKDQGVTYFSSSVTLGPNGVEEIHPVGKVNEYEQGLLDKCLKDLKGNIEKGEKWAQSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAQ7</accession>
    <name>A0A9Q8LAQ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_02368</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758175.1">
        <property type="nucleotide sequence ID" value="XM_047901516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAQ7"/>
    <dbReference type="GeneID" id="71982246"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02368"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF39">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0964">Secreted</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="633"/>
        </location>
    </feature>
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        <location>
            <begin position="234"/>
            <end position="615"/>
        </location>
    </feature>
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        <location>
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        </location>
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        </location>
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        </location>
    </feature>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
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        <location>
            <position position="575"/>
        </location>
        <ligand>
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        <ligand>
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        </location>
        <ligand>
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        </ligand>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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            <dbReference type="EMBL" id="UJO13809.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="633" mass="67953" checksum="ECA5A8AE95E10C10" modified="2023-09-13" version="1">MLVTHLLCAIGTITTAYALPQNVRSDYAVKERHNVPKAWTKVGEASKSDMVHLQIGLKQQNEGVVEEHLLQVSDPSHSRYGQHLTADEIKKIITPSDETQDLVKAWLDEHGISNGVHSPSKDFIHVVLPIGKVEHLLDTAYSTYQHEDGETISRAAEWSLPKHLHEHIDVIQPTTSFFRAKPQIIGGPDLKGDTHPMSWWKKYSKQHFGRETGGQSSTGSGGAGPISQVCNVNYTTPDCIRTLYGTYDYVPQVPDKSKVAHTNYLNESSNRNDIHLTLENFRPEAAQAAYEFENVIIANAQDNQVYTPAIVAAGTNIEANLDSINILSVSWPLNFTVFSTGGSPPFMPDLVAPTNTNEPYLTWLDYVLGEQDLPQVISTSYGDDEQTVPESYAKRVCAGFATLGARGISVLFSSGDSGVGPGGKCFSNDGKNTTQFLPAFPAGCPWVTAVGGTKDFQPEVAVSRFASGAGFSNYFSAPSYQQSTVNAYIKSLNGLHDGLYNKAGRGYPDVAAQSNRDTIVYNGNITTIGGTSASSPTFAAIVALVNDALLAEGKPVLGFLNPWIYGGGYKALTDVVSGSSYGCNTTGFPAQAGWDAVTGFGTPNFPKLVEAAFEKYGGHGGYGGPKGYGGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAU0</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
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        <source>
            <dbReference type="EMBL" id="UJO13946.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="33258" checksum="E54C4C04951E00BE" modified="2023-09-13" version="1">MAGPGETVRFAGSINSTAGAGPESGALPPTDNHPPQPGTAATMRNPDPFSIIATANPAMPAYDLMRMLNDVGAVNRELQTEIMGTRDRNVFLSRENFGLAHRAKWFEDESQRRQNDINNLLTTIREQRLDLDRRDETIRQHVITIRELRDSHADIDAQVTGVRATVNELGKHLPKLLNGEVEMEDQEGGSEGEGEHVTEHVTPAQAAKRKIKGPARQASSVEQADVEEREDVSVAAPVTRGVKRKRGGEAAAKGAKRKLGKTPPAAPTSEAADNMQPSSAEEEARYGASFYNTYVTDDVPEGYAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBQ6</accession>
    <name>A0A9Q8LBQ6_PASFU</name>
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            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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            <end position="154"/>
        </location>
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        </location>
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            <end position="267"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="598" mass="66640" checksum="560B1672C0B0CDEC" modified="2023-09-13" version="1">MAPKSKKRKMTVAQPVAQSVTAAPAKKEPPKTTFMDLPVEIRCEIYGYVLEEPTPIKLRIQFHKKKNGPREIVRIFHRRDPKHHGQVYDKKTKSWIPKQYTHSSILLVNRQINEEATPVLFAQNGYFLETTAALRDFLELIGASNVRHLRRIIIGADGYKANNARAAFQALTAAKGLRALEIDHSNLCAPQGRESTTTHRLAGDCRTLLKSLKASYETLNLFGSVLDVLSVTLRPCKAWSHPPPFSTVGHRRGHEGGGSKRMLRVSDTNGRQAASISNATLESSTDGCSLASGDKVGRPATYDDVTGTYKHMVNIQDSSSFCIRTYTITSGALKGCRTIILVPAGSFRLLDLPGEIRNMIYKCVVMSPNMISLETYHPKGHGERVVQTSFKRKDHKTKAQHTKKFEVPGPNSDTASLLLVNHQIHDEAVEVLYGHNTFSFDLTDTLKLFIKINGKCLPYLRFIELDCFWHLVPDKVVKTLKAAQRAMWRAPGLRKVQIKHHAVCSSTSLDAEAFVDVFAPLLQKIQNFKQAQGINSNMTELLEFPACSCDDCARRKAGIRITPFARGPCAGNPKCVSNQTDFPQQVKEVVAKKFPAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBT3</accession>
    <name>A0A9Q8LBT3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02343</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758234.1">
        <property type="nucleotide sequence ID" value="XM_047901491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBT3"/>
    <dbReference type="GeneID" id="71982221"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02343"/>
    <dbReference type="OrthoDB" id="89349at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF11">
        <property type="entry name" value="CONCANAVALIN A-LIKE LECTIN_GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17180" checksum="7F5554A401DD8EAF" modified="2023-09-13" version="1">MVWVGQFGTAAQPVGNRTPRDPPVVARLNSIDFTLWNGTNTNGQYVYSWIANETLTEFDMDFAPLLGFLAHEEGVSEDVYLGTVQFGHETFLAASQMNFSISSYAAEIRSNRAEANGTSEPTASLPVATKVSTAPRRCDISLPSMLSLCVVWLVIGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC84</accession>
    <name>A0A9Q8LC84_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759148.1">
        <property type="nucleotide sequence ID" value="XM_047907174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC84"/>
    <dbReference type="GeneID" id="71987904"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08026"/>
    <dbReference type="OrthoDB" id="3255572at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="63137" checksum="580B4CB806A9FC9D" modified="2023-09-13" version="1">MGKAYSEEQRLHVKGLLEAGRDEESIEKETGVSDRTIRRWKLELERTGRIGKVRAVKRSTTTSDLDKADNMPQQPPEARTGRHRVLTPDVEQALFEHVKEKPEMSVDDMLWWLYDKYNIVVGTRTIRRVFERKGDKVKMKNTRRKSGTGEDDDDEEDEEEGDTTMDTTAQPQNNAQYQSPYAPMAQQTAQSVEAQMARALQQQQSSPQQSFSTPMNLDADLPEDEETIELQLQQIALAKREVELKLKMRQIQSRKNSSVSASPVSVTKPAPKRQGPSTLYNPNAVIPNVPKRDSRSKKKIEESKKRTAERQERMLRDLERRSRRRDHLTAEWVQSKDIWPLRAQALLADLMHQYQCYAFQQSQLDTFETMYRELYQLVDMNKGDWNAPIHDEMLRERMKRKMGQLRTKMQKTGEIVGRADGYGGFTKADNYTGEQAGAAVGDDNENDIIVEMNTHDLQAQPGAQDMQQQDMQQDMQQDLHQELQQDQQIQYDPLPDHQQMQQVQMSYTHTPMTSQGPGQYPLLDYSQGMMPYGNINTQMSNAGGMGMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCC8</accession>
    <name>A0A9Q8LCC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759189.1">
        <property type="nucleotide sequence ID" value="XM_047907145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCC8"/>
    <dbReference type="GeneID" id="71987875"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07997"/>
    <dbReference type="OMA" id="GVFAAPW"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="58592" checksum="5896F2D121AD929C" modified="2023-09-13" version="1">METTFISIHDLTDNATILYSSDSVVDILGYTPDEIVNRSAWEFFSLDELPFAKDFYQKRVATDKAAVLGYCRVKDSHGNYVGCECCFTIVYDVMVVCTSIYRRGLQADKRAAEAPVVRRMFSSSPKDPRYHMLSHLSTKFSQASKNQDHEPRAALFLNRFTRTLTIMYATSGLQDVIGIPAETMRGRSFYYCISENCLPDAVKCLENAKGNDSIAYLRFWFRDPRIDDDDPAVTESEDSDEEMTTDTSVDGGVNLGGEPTSPGAAMDIDSDESKYGSRHSSGDSTRGPDTHEAIFGEARRAESSTSSLAASPERGRNSPTRAQEDHIELEAVISCTSDGLVVCLRKARPMIPHPTQRPARPVYERGLFAAPWASEPVLPPLETRGAAGFGSSFAPSLGPHGARRSSNVATAHGNGKAPEQSDFMNAIREQAIFAWALTGINGSLAEYGQGRPSGESLPHDGLPVWASDPRYASDSDRGSSDYRSGSDLPEPNKIDGRSAGPHIFGDPGLGRNSNHSSLGVGSGTNSANHSSNGTPYTGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD15</accession>
    <name>A0A9Q8LD15_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759490.1">
        <property type="nucleotide sequence ID" value="XM_047907107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD15"/>
    <dbReference type="GeneID" id="71987837"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07959"/>
    <dbReference type="OMA" id="IAGIWMN"/>
    <dbReference type="OrthoDB" id="5391043at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="333"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1060"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1116" mass="124376" checksum="D6DB69E3C2DD575B" modified="2023-09-13" version="1">MAPDIKSEDFAYDNGRPLTADTSAAEAALKAKLSRKRTKTGCLTCRKRRIKCGEERPVCKNCIKSKRLCEGYNQRVIFKQPTFDYQPAPHGGAHITFQAGFLAGPASSHPDIHPPGFDPSAFAHVQQQQHAQQYIQVFDTQLQQYVTIEQPRQQIIAHMEPPIPHGHSQHLPHFPQAAAHPFNQAQQPSFRAQYLDTTQEAAHNVPSLAPAVELSNGYATASLQSVAATAGLFSPHQSNQQNGQMLPVVTMPTEHISDAYRSAHEPVDPHHNVKFERAHMQVWSNTKPLGTEQDIVVPTPVSDTSSRTLSFSQTPAVAVRQQRENNHYVPQPEVARPIDHAPPIEQNHYHQTSPSLSGPQPSANGDHVTPEYYEHEAHAAPYATPTYMLNVAAVEVQDDDYYDVEQDDEMDVDTNASPEYGIERQRKLSRILALNQISIHDVQMRRYDTFIYAGILARYKVEEVASPLKNPATARVFAHFISATGPSLSIFERHPRNTSMMFNESSIPLSQQGLWTYTLPVAALRNQGLLHAMLALASLHIARLQNASVTPSMQHYAWALKRIHNSVATPKGRLKVTTIAATMLLGFYEVMTADHMKWNAHLAGSKQLFVDTDFVSMTKEFRRLKRGKATRHLRRHSSEEPWMQDDLLDQTMDVDERVVSHMVGKEVRYDDHGGIETPRVNIPPGLDLSKFEILKDLYWWYCKQDVIQSIVSGNHLLMDFSRWANCPPRAPLGRGDAVHGTFDHLVLLLGRIADFSSRDRERKLKQMEANGGNWRPAPEMNIPRPPQHPSVPPTPVSATNSFPMPGTTIPPRGPPGGPQPPAMPQFFGMAPPPRANVQMPSVYRPTQPTTSPQSARPYDPFEGDLQAQTAAALEEYGRIRAALHTFQTSLGKDFEPLGPDYYVPEMTAFGQALVYRSYDIGCMWALYNMAVIIAIRAHPHMPPAAHVAAAIAAHETAFFANEIGRIAAGIVPGPPEQALNPSLGAALCESCMPSFFAAVQYQDPHQRRETVTRIWSIAKRTGWGSAELIANGCETAWVKAAAAGRGPPYERIARPQEFTHDPRLNGSWERLDPNAQPNEMDDTDRRLVKKKAQARLNWAIGVMGVEDDVHKIHLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDA6</accession>
    <name>A0A9Q8LDA6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759631.1">
        <property type="nucleotide sequence ID" value="XM_047907592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDA6"/>
    <dbReference type="GeneID" id="71988322"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08444"/>
    <dbReference type="OrthoDB" id="10489094at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="232" mass="26684" checksum="B63F4A3B5CF4969E" modified="2023-09-13" version="1">MMAESFPFFDLPGELRNMIYDHTLQRQDDRTCCMDIYLETFAKDLVTVSRQFAKEYRESRAKSVSRLTITKTLAKGRSKDAIPCFLGHKQLDLSRLFTTATHLKLNLTAFLFAHIHAHRAWLARLVPHMRGLKQAIDIRVNVRIFNQNKSDALNAIEQIRLELNEITWMRLVCTTTLDVHYAKNEAEFRNFGFDNLYMSLSAETGKVEYCDEGAIAVTRCASAHDSDCHMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDF2</accession>
    <name>A0A9Q8LDF2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759555.1">
        <property type="nucleotide sequence ID" value="XM_047907681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDF2"/>
    <dbReference type="GeneID" id="71988411"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08533"/>
    <dbReference type="OMA" id="FETKAKM"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="469" mass="52159" checksum="C9C3F59ED0BF57D0" modified="2023-09-13" version="1">MEEIAPEYDVVVLGTGLTECILSGVESVKGKKVLHMDRNDHYGGEAASVNLEAMFKKYGNFDNGTEPWKKYGRSNDWNIDLVPKLLMSNGELTNILVSTDVTRYIEFKQIAGSYVQQGSGAKATVAKVPSDAGEALKSPLMGIFEKRRAKNFLQWVGSFDENDPATHNGMNLSQTTMKQVYDKYGLEATTRDFIGHSMALYTTDDYINAKGAAKDCIERIRLYVNSMARYGKSPYIYPLYGLGELPQGFARLSAIYGGTYMLNTIIDEVKYENGKVAGIRATMKERGEEGEGMKFETKCKKIIADPSYFPDKVRVVGHYVKAICILNHPIDKTDNADSLQLIIPQSQVGRKHDIYIAMVSSNHNVCPKGYYIAIVSTVAETSANHHLELQPGLERLGKIEEQFMGPPIPIYEPIDDGAKDNVFISKSYDASSHFETMTDDVRNLYQRTEGEPLVVEGLKDGQNLVGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE30</accession>
    <name>A0A9Q8LE30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fusarinine C esterase sidJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760066.1">
        <property type="nucleotide sequence ID" value="XM_047904153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE30"/>
    <dbReference type="GeneID" id="71984883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05005"/>
    <dbReference type="OMA" id="PPWVNKE"/>
    <dbReference type="OrthoDB" id="10034502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF7">
        <property type="entry name" value="DUF1749-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="333" mass="35950" checksum="3CED9580B1C02CE5" modified="2023-09-13" version="1">MDGALHIIPTNLCAFEPTKPLVRSANINTLVWIGGMFDTLGSVAYPFTLAEALPQAWSLITCSLGSAGMAWGVKSIGTDAEDMAKIIAYIKKKRPGGKIVIMGHSTGCQDCMEYSVGKNAEKRPRVDGVILQAPVSDREALEDELPQAHKHEADQLALKMIREGQDKDAMPNKWTKPIFGRLAVTAKRWVDVSSPGPDHSGADDYFSSDLPPERFKATFGKLPASSPLLILYSGSDESVPSKVDKQKLVQTWIDIVKASGGSVDDKNGGVVAGASHNYNGNPEEVVQDMVKRVLGFISKLDEGDDPARHEEKAGGARGAEPVQLSRNILQGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEK9</accession>
    <name>A0A9Q8LEK9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760344.1">
        <property type="nucleotide sequence ID" value="XM_047904272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEK9"/>
    <dbReference type="GeneID" id="71985002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05124"/>
    <dbReference type="OMA" id="NWGGRTK"/>
    <dbReference type="OrthoDB" id="5229455at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF43">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="809" mass="89187" checksum="A31C50EEB396F344" modified="2023-09-13" version="1">MPRAKTETGVEPKKRSRTGCWPCKARKVKCGEEKPACSNCVKTGETCDYSIRLNWSGRSKKDKDGTPGESGTFTFVTTPTAASPARSNGHGHDHVFSSQHLATAPQPRPPSSRPVAAPTPPPMQQTVPQPMPQPMPHAMSQPMPQSTPQPIAVSESTSLDPRLRMVEQYARSPAFPPSPYQPMGSAHHSPTLTGRTSPTSMPTEDAFSWSPQHRAKRVKLNSPPLQPSPMFAVPHYPSHIEQSPGSTHVTPHSISSIVNTPATPSSSVNSGSPYPAQPGALGVQDPPDLRRLSVKSLLSDPTEDDRPRFARSDSTSYRTYGYDHGFADLDVPRNDDTNVVLPRSPDLRRASAAVSQNSASSDEADTAQIAFEPGGYYAQPVAIRIPRALEPLPTELLENQMNLLYFHHFINHTGRIMVPHDCPENPFRGVLPQMAVKNTYLLHLMLAFSASHRARLLGHAEPANRIAQWMADVLPALRQALNEPSSPGIADPRDPSSLAPLATAVMLASLEIISPHTFTVRISWQQHLEVARQMILAKGGLHHLAQKADGARDKAIFFLSRWFAYLDVMGSLSNRQMRPLFGAYDEDGGGLWLVNRDGEEIYQIDCFFGFSGRCIALLAQVAALAAECDNQRIDPVTNQIKAGWTPPDAFRHEAEELEKRLNASANTVFRGCMHTDPTFPQSPNAQDEKDSAEIYATNEAFHWAGLIHLSRRVLALPTSHCQVQDSVEKIIRSLQQVRRGSTAESCLLFPMFTAGCEALVEDQRILFMDRLKEVEGWGMQHVGRARALMQEVWDTGRPWETLVNGEFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEL1</accession>
    <name>A0A9Q8LEL1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760467.1">
        <property type="nucleotide sequence ID" value="XM_047904522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEL1"/>
    <dbReference type="GeneID" id="71985252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05374"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="313"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="490" mass="54650" checksum="A7D3BE3A73925F1B" modified="2023-09-13" version="1">MAGPKPASNAPTPRRTADEDPCDVAADDSEEQPDGEDPEEQQGEEDDEQPPMPNNYLYHRPRCIFGLLPLATRQHAVLPDAAARTLDSDRIFAVHTDVLQAKAPSLYDDVQRAFAQSPPATVCELADVDGDILASALAWLYTGELISYRKPKGVESLGEAVSPRMAKGNGGRLEAKDITVWEDEDLVAVYARAKRWDMPDLMDLAISQLWIQNKLAHRSVSARAVAAVFDDDELSGSSMADFIPAYIAGVLRAVLDVQKRPECFFAEQTLCENHSHFGMTKTCNEVFENKRPPKKALTRCYQLPSPLEEAVGTITVGHRAMQFTVHKALMSDCSTFFKAAFESRFQESGTGDVVLQSERPSIVALMLEWVYTRRRALPALENAQALDALDDVGSDFQSRVFRAEASRYRDIFNPDGERNPALTALFQDDDVDLYILADRRGVQDLCDSLIHHFKVDRLEENPLLTSSTARVKKAYDELPENSPLLRYLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG56</accession>
    <name>A0A9Q8LG56_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761154.1">
        <property type="nucleotide sequence ID" value="XM_047904470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG56"/>
    <dbReference type="GeneID" id="71985200"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05322"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="11979" checksum="ACBCFD5727A76409" modified="2023-09-13" version="1">MLSIMNSPNNRTNLARLLYNFDDFLRHLYDHWIKTRPLLYHYGLLSDDDYAIDDAFKQEHQYLVEEAHAAHWSQWAAVSHMVLGDWSMRCRCWWMEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGM6</accession>
    <name>A0A9Q8LGM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761458.1">
        <property type="nucleotide sequence ID" value="XM_047904384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGM6"/>
    <dbReference type="GeneID" id="71985114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05236"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="32705" checksum="6B7F4009D81890C5" modified="2023-09-13" version="1">MSATLHPIPSDQDLVLAYSCTHCESIRAPEVQRLKTEAEYVHTTSSGCIITRSDFYEGWTGTEHGYVQLTTPCSKESCQALTLAEHEEQLYATIKTSRMSFQNTVFNYVNCGIRYHKKPLTLRAKTADETHLAIVHHTYGIETRYWYDDPFLQPFLDFHETLQVFEERVRDGIPCEEDVATALRYLNTFRAIAMKIKPIIETLKEGVKTLATLESYGHAEHFHTIVPGRLHHLKVFDKVAETAVQKFVAEQVIFDRWAARIDEMGELYTGNTPLPTFRTSVACPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH66</accession>
    <name>A0A9Q8LH66_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761743.1">
        <property type="nucleotide sequence ID" value="XM_047905529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH66"/>
    <dbReference type="GeneID" id="71986259"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06381"/>
    <dbReference type="OrthoDB" id="3827811at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="60321" checksum="C4547034D6244646" modified="2023-09-13" version="1">MAARRPSVCLFCQSRQLALSKRTAHSTKRRLTTISRRQLEAIALRPEDDGFLLSEKERAGEQSEDEEPLLSAVDARRQWKLYNPIDELREAALGFDALVKRRDLRLEVLRSLSNPWPQVPAGRQHTMNKPVLPEAKAAVIPHTTFRQRLRDALGPKPVRQVLRQQLLRCEYPKEILRVVAVAMQHRASAKHLAVLFEPLMRALYRCRQNVSDPEVLRCLNTIIMRFRYADLEVQPQLLYMALKFAARSRSLPAMKKFLAMIRGDGLKLSSNVFRSIIAKFSIGHRGLGEIRNGRWKRQDLMQVLTGFPDCADLPSDQHYHLGSFLFRDDWQYLHGWVAVLGRCRASELVWEEWELWKHTKASTEPRKLLIKEANAAAMTSKLRGDIWFVEQQTHSGDLKRAWQLLSETSIPFSSLKMRIKDKLLEEPEYCPPAAWTEDVRNEMVQKYDRELSRVEQALGVKWTPGAEDGSGDHTLTMDQEEALDKLGERRWRSDDAYGYPWETDPIVPENERGLHDAEEGSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ1</accession>
    <name>A0A9Q8LHQ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762013.1">
        <property type="nucleotide sequence ID" value="XM_047905136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHQ1"/>
    <dbReference type="GeneID" id="71985866"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05988"/>
    <dbReference type="OMA" id="WVEGCET"/>
    <dbReference type="OrthoDB" id="3650499at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040230450" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="16998" checksum="853907178BE3E1F1" modified="2023-09-13" version="1">MRPIYLLPLLPPLLSASPTPVTKWFNPLEVTNITCNDPADFEGHADIYGDFQYKNALYLCNYEWHGLTMDPSSKPLYQRESPYGVSYDYSISWVEGCETTVPSQDVQVPLNDQAPGWSCHAIFSTLYKGCINGGIGGYLIAGCLRYQFDGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI64</accession>
    <name>A0A9Q8LI64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4-hydroxy-2-oxo-heptane-1,7-dioate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762196.1">
        <property type="nucleotide sequence ID" value="XM_047904927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI64"/>
    <dbReference type="GeneID" id="71985657"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05779"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF9">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="3">
        <location>
            <begin position="65"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="26640" checksum="BB8CBC96341DDA7E" modified="2023-09-13" version="1">MFTLTDKPSNRAIILLRASGKRVATMATPKLLNTLRNGQTAMTTFLALKGVRHAQVVAHTGLDAAIIDRDVVASAGSSPIVRIRGPSASLVKRAPDTGAHGVLVPMINISPTGVQGRGSAFAAFEHGLSTPVEYVASANDSVVVMLPIESIEGRNDVDEICQVQGVDRVFIGPNDLALALLGSTPAKYTEAKFLAAIDKIVGAARTHDKEVGMLVADGEQACAAKERFDLIAIGTDVRAMQALYRAALEKARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJF4</accession>
    <name>A0A9Q8LJF4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Kynureninase</fullName>
            <ecNumber evidence="5 6">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BNA5</name>
        <name evidence="7" type="ORF">CLAFUR5_06899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="5 6"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJF4"/>
    <dbReference type="OMA" id="SHVAYRS"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF2">
        <property type="entry name" value="KYNURENINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="174"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="484" mass="53952" checksum="ACC4B4B273B7AF1F" modified="2023-09-13" version="1">MDAQSAITQLRNGEKPTWPQHAASYDFAQSLDNSTTTFRDHFRIPTRAQLKRTSIVDNEKTKAPADKPEDCSIYFCGNSLGLQPKAVSEYLDAYLTTWGSIAVNGHFTQIGDSPLVPYQDMAGDCARKSADIVGASPEEIVIMNTLTVNLHLMMAAFYRPTEKKHKIMLEWRPFPSDYYAIESQIEWHGLKPEDSMLKVQPDDGYIITTAHVTSLIDKHADELALILLPGIQYYSGQLLDIPTITKHAHDRGVITGWDLAHAAGNVELKLHDWDVDFACWCTYKYMNSGAGSIAGAFVHEKHGDSAKNKALKGWYGHEKSSRFLMDNKFVPTPGAQGFQLSNPSIVDLTTLSASLSIFKQTSMKDLRSKSLLLTAYAEHLLNQIAERTFDGSYPFEIITPSNPLRRGAQLSVLLREELMEEVSKSLEAAGVICDKRKPGCIRVAPAPLYNTFSDIQRFMETFEKALRAQVAPKNESSEGVEARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3R2</accession>
    <name>A0A9Q8P3R2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GCS light chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Gamma-ECS regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Gamma-glutamylcysteine synthetase regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamate--cysteine ligase modifier subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00831</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of a catalytic heavy chain and a regulatory light chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756559.1">
        <property type="nucleotide sequence ID" value="XM_047899979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3R2"/>
    <dbReference type="GeneID" id="71980709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00831"/>
    <dbReference type="OMA" id="CTDILPR"/>
    <dbReference type="OrthoDB" id="5596051at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035226">
        <property type="term" value="F:glutamate-cysteine ligase catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032963">
        <property type="entry name" value="Gclm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295:SF4">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="11">
        <location>
            <begin position="84"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="322" mass="35409" checksum="5052425284EDF35F" modified="2023-09-13" version="1">MKLIISTSNILSAGSSIRRSPKNSKSNAEFIESLRTNFAEHSAITTNGQVNGDSRPKKVDYQSWTTKRDGTLEIPSLDFSDSALAEEKAQYDITVKLFYLPGATKDTRATHTREALDLVLKELHIPSIDLLIVSFPGIYFDEEEDCPDKLSTRGPVEAEPEPLEGQLETWKTLEALHDEGLVGRLGIAEFGKERLKSLLDKVRIKPSVDQINLRDCCSVPRDLMSLAKSRSVELLVHNDCSNVLPRGTLRDLLGPEGAAVLSEPSKAGDKRKSLHGEENTNGNHTAGLSGEVQPQWVVKYTAVVKNRGVLENKGYFAVADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3T9</accession>
    <name>A0A9Q8P3T9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger CCCH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756530.1">
        <property type="nucleotide sequence ID" value="XM_047900434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3T9"/>
    <dbReference type="GeneID" id="71981164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01286"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="336"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="336"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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</entry>
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
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            <begin position="82"/>
            <end position="171"/>
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            <dbReference type="Pfam" id="PF06985"/>
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            <dbReference type="EMBL" id="UJO12375.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="560" mass="62736" checksum="970186AE930A793D" modified="2023-09-13" version="1">MAQEVAGILAAEVLSLPFREAKIRLSKAIASKGVDRISRKSLYKYQPLPDQEHIRLLWLSKDDNGELCFELDAVNLGNAPLYEAVSYTWGIPSRTAFVSHRYSGRRLNITQNCYDVLQNLCERAPRVLWIDAMCINQDDLNERGQQVAIMARIFQGALRTIAYVGPSDDDFTHVQRACAEFGNGTGVFGPLMRHVLHQVQDHGARSREYLSLLRTDDDIQAHVGCSLFLGEDYRLIARGILARRTLYWQLARLQYRGPLVQLARKVEHCLRFLVIETNAIYTTAYTFWGRSVRYDDRSMRIAALKVENATKALKDCLWALDEEALMLRHIRTCLVLPDKGLVFAAPKYTAVDGGAAVEIETSALPDYRSAIEHSEVGTRTTVVSYSERRPTPTAPTHSRDTAVALLSSAALDGGQNHVRVARLTSCVLHLSGVWKDRLEVPFGGLTSYESAEKAALHRINTTCDQWRMVFVAMSALGAAFGTLFNRPWFSRTWILQEVLLSPRVVVQAGRDSFPFADLRLIIAIDPRLASDMLSNPGNVVLSDYLPSLGLPKLFKIVAEQ</sequence>
</entry>
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    <accession>A0A9Q8P3U1</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="289"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="88" mass="9860" checksum="FB01B5D2D21389AA" modified="2023-09-13" version="1">MASRKNAPARRERTVLIPRDGRHLEQSEWPREDVVVPLLFVHRQHLLGGNDVLARLAMEAPTEAANWRAGVYLVSIAKGRNVPNEAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P622</accession>
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        <name evidence="2" type="ORF">CLAFUR5_08452</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_08452"/>
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        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="entry name" value="DUF6570"/>
    </dbReference>
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        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="23682" checksum="3F5496A22EB3F201" modified="2023-09-13" version="1">MQLIYDAGHEPDDIDGDAQMADAFEPSDQHQVCKRCRHGRDSAKGLGDPFLMSAANHMNPSLGPAAWDLPAITQIEEQLIAIVHVFCTTWVVGGPLGQHKYKGNVIHFLREVGRVYKELPLIPTEVTDVILRPSETDQAQGRMFAREFTVRCAVVAKWLDHLKNRHPLYRDVVINPDRIRELPEDGNVLEMGLCNTSAMDGDNDEVPAMNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P653</accession>
    <name>A0A9Q8P653_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_08566</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71988444"/>
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    </dbReference>
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        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="26809" checksum="636650CFD8E8AD59" modified="2023-09-13" version="1">MLATSETERQQREAANSQTPLGKLPGELRNRIWYLVLPTGGVVNTRSDDRFTSSESVDCEIEMEYHDCSNPNITEVCRSIREETLGIYYGSNTFVLHLDRAQDCRTCTVDDDESCTLIVAEAKYWIRSRSNPAIEALRTLYLMLPPWEPDPDENGHPREHDGYCRTLVRVDWVSQKSKLWPICNACTVCRVDLDLKLLGVPGTVEVCTGIAASFPGTKAAKLVKLVTEVKEALRDDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6T7</accession>
    <name>A0A9Q8P6T7_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="481" mass="55360" checksum="3D3117872A017849" modified="2023-09-13" version="1">MAANSTLFASIAKDRVNAKQPPSTGDDLDVDRCAALHNQLLLYGWFCSGKKISAMEKRSWWGKHGNDSLKKVLRPKVVRYLSKVFDVERHNFFYHVSGLASEKEMLQLADVLEDSDHGPVHTEKYRFVVLYKTSEALVSKPAGIVHDQQTGKALLMPTYHHLFDFSNAHLPWQKMERILSAYIDMIEAEKAVAIHDEAGKHDEGMHHPRQELEQNKMLARYKTRPWILQPYTLNDLYACLDIWRRLVHGLETRAGVANPINLDEEDDDEEDYAPLCSSTALNVAGIPQGFAYQLLSHAQQSQVWFLAPGLRLPKVEEFLQQPFKKVLQQYPEETRGMKMPFLFLRCEGTVTAKEGKFRYPFSTVERVPCGLYLDAFPNAQNPFEDACRLVLPIKLGNNRYARTSDFRPIIRSHSDLYQTGVNPYVMRHGPKLVAVLENWLAQVESGHWSVNELGVSDDIEMWKQADTRDNWWRYQSEHLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7K9</accession>
    <name>A0A9Q8P7K9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2 3">
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        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7K9"/>
    <dbReference type="GeneID" id="71985018"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="727" mass="81460" checksum="B77B39ACF2BE0987" modified="2023-09-13" version="1">MQTTVSRPRAACHRAYCSNGQSPVIDTCRNRPRSMPWRCRDDASIPRDMSSTVVVHSPGAGLTIRSWHTLLTGHTLGTQLASRNDDARASNITPFPARHGALRLRLRHSTRRKSQAPVRSPKMLQDTPPKPGKLPRISIRKRRPERREDGTTSPAARSSKLYNGAVVVAVGDRQTVMPSLVRNHENGSIGTSPVPSEDTRMFDEALEILSNLPDPPAATPDKSSWHGAKFAVDEIVGQGKRHDTTVYKVAWKNSKVPTRLLRAEDGRDTVRCDKQEYIVRSYCPVSPELGANNEPHLLIDWKSTWEDEGFVLECANPQLEDFLRKMRESQEIDEASSNERQTRTQQQSTSASPTKLRPQGIVYSPSFRPERSQVYNDALRRLLRGVAGDVGKLLSMPDSNDLIFRKRYLQRTFNAECPKMRRAAALQMVGMMQKKKCDHCTRGLGPFRGCVVLTGFARGACANCLYSSRMPMECNYHCQSRAKDGPWTPVSASEHAQRRRDAVAASDGSWPRVVASPAVDSPARRLAAETQDTRGQSLTQLEARDPETVTCVFDARSSPPLLALEPQRSDAAPAKQSKVTNMPALVEPRYLSPLFRHAQCLRSRLRCADAVASYSNKQRKGGHVARGQIFHAGEASVEQVRWLTAMSGCSMTEYMHRAWLWRLQKRDLEPLPLGWRKETFISYYHWAELNWMADQIGAANKQKKKAGKKAKRGRGRGGKWGRRGSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7W7</accession>
    <name>A0A9Q8P7W7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7W7"/>
    <dbReference type="GeneID" id="71984894"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05016"/>
    <dbReference type="OMA" id="GYLPYDH"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="171" mass="19298" checksum="8E6ACF7D601428CE" modified="2023-09-13" version="1">MSQHQCTIRKVTPQDTPEVLPFITAARHSLFPGLKFKTTILPEDVSSWIASGHFLAAYTTKSPDHLIATIGFVPYDYRFPRLEFHGRKTVEVVRLFVLPEYRRSGLGNLLFRQSRGTAEGLGVEVMYLHTHPFLPGAVEFWENVGFGVVGVEEDEGRRTVHMKLELKGEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7X5</accession>
    <name>A0A9Q8P7X5_PASFU</name>
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        </submittedName>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13596" checksum="7E02698E5544C502" modified="2023-09-13" version="1">MKCATGFSGLPDSYARMRWRFILTYEDDGVRNDGVEQSPADAFDREHFAHVRNAFDVLNEAEAHLRELQEAAAAENIADPDELDVFIGMDHPDDGFATTHNTAAEEQHHIRTASARPRILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8D2</accession>
    <name>A0A9Q8P8D2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71984766"/>
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    <dbReference type="OrthoDB" id="10587890at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="124" mass="14092" checksum="ED63B84D009DF88D" modified="2023-09-13" version="1">MMATTLSPMELIDQELDASFCGSSPTNSPPPEPLSDEDREKAELRAALKLELQAEHHEELKALTRKLGEMCGKVKDDIEMTEKLRRQVNERHQSDIEYGGGCFLAGLFLGMAICVSWEEWLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8T9</accession>
    <name>A0A9Q8P8T9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06214</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761708.1">
        <property type="nucleotide sequence ID" value="XM_047905362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8T9"/>
    <dbReference type="GeneID" id="71986092"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06214"/>
    <dbReference type="OMA" id="CGSKWYT"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040232200" description="Mannan endo-1,6-alpha-mannosidase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO17342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="46434" checksum="2AA67B4E9FEDA035" modified="2023-09-13" version="1">MKISFSSILAAAAAGLQVVSAIDLDPSNVTSIKSAARTLAFGLQSYYVNNQTTTPPGTIGTFPGPTWYWWKGGAIWGGMVDYWAYTADSAWNNVTQQGILAQVGPDFNFEPPAYNGNLGNDDQAFWALAAMSAAEYGFPVPEAQNDIFWLDLVKTVFDRQIARWDTLTCNGGLRWQVFEANAGWNYKNSISNGGLFQIAARLARYTGNQTYIDWSEKTWDWMSDIGLISSTYQVFDGTDVLKNCSELDHTQWTYNPAMMIYGTAALANLTEDQVWKNRTEGLLTSIENNYFSMFTNATDIMTETACEPSNNCDDDQLSFKAYLSRWMAKSAVVYPAILPNVQKYLTATAQGVVKACTGGANGETCGQKWYTGGYDGRPGYDQQLAALETVQSLLLLKGVAPETYPDTSDNVSIKGMHHNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9T8</accession>
    <name>A0A9Q8P9T8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762682.1">
        <property type="nucleotide sequence ID" value="XM_047904662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9T8"/>
    <dbReference type="GeneID" id="71985392"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05514"/>
    <dbReference type="OrthoDB" id="3622878at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="87" mass="9766" checksum="EF2CC500FE1E16B1" modified="2023-09-13" version="1">MEQLTKANPEYQLTIADMTTYVDQTTVGSLRSAKVWVEVDVTGQPVGVSWKGLSIVEFRCRRGKWLCVGWEGVRGRMQDFMPDVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9X1</accession>
    <name>A0A9Q8P9X1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762943.1">
        <property type="nucleotide sequence ID" value="XM_047906329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9X1"/>
    <dbReference type="GeneID" id="71987059"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07181"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="107" mass="12207" checksum="387DA37C8D9DF028" modified="2023-09-13" version="1">MKQAHYEQADVRGFPPQPKGELVVLRGSNEGIDLENWKLERALVPSSSRRAAALPQRNSRPDQSHNNEDSDDDDKSKDEGDNDDDEPGEDEENSDARTSRLWNRYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAB3</accession>
    <name>A0A9Q8PAB3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763132.1">
        <property type="nucleotide sequence ID" value="XM_047906545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAB3"/>
    <dbReference type="GeneID" id="71987275"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07397"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="33903" checksum="19C8C8F6828C938C" modified="2023-09-13" version="1">MTIARKPIRHRAILVTFGPSEPRRCTSYLRDVLRALTAHGSLVEGDGEQASADRVHHCILSTKSAEEASAQSSKTLHGLTEEIKDAEEKITIYYGGHALQHRRSGWSWHADAKQQACEGHFPSFDPAPALQEFLREVYNDVLLIFHCPINIYRHLQFDLSPSVHFPDRSVQLVHLNMPWSANTNTNTGCEVSHRKSEAHRCFGGVVVNIPEFSESPTRQLANQLRTYVPGAATVHNLLDDLTHAAGAGLQAPYWRPILGKPEDFFLSNDVTVDSYQSALESARTTQLKRDFRLHKMCCWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAY4</accession>
    <name>A0A9Q8PAY4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763498.1">
        <property type="nucleotide sequence ID" value="XM_047906450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAY4"/>
    <dbReference type="GeneID" id="71987180"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07302"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF71">
        <property type="entry name" value="EPOXIDE HYDROLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="419" mass="46637" checksum="5DC4983BD972E465" modified="2023-09-13" version="1">MATPSSTSDRSPGGSSDTILPYRMHVSQRYLDLTRQMLELTRLPRDVSSRHLQGNKGVTESQLEPLVDHWTEDYNWREQEAYYNDALPQFRLAIHGTRVHFVHKRSMSPTAIPLLVIHGWPESFITVSHMIDGLCNPVATPPRGDENVPSFNVVVPSIPGFGFSDQVSEEGNNIATTAEAFDALMKSLGYARFIAHGSGWGFKISRMIALTHPESCIAIHTAIPAVPPPRIHGSFWPVVPQVPGMTPPLSPGSQQQQQRERPQTISFALCDSPSGLLAYVVDAIQPPAPPPGTQSHPSTPGSPRLADLNPWTETTLINWAMMYWLPGPEVALRWLVISAPMLPNLWTVRGNVPLAISQFGEPLQPQTGPMWIEAYHRIAMVRRRPGQSRFPAWERPMDIVMDLRELAMLIGPSYFGMIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB92</accession>
    <name>A0A9Q8PB92_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase Nek7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763613.1">
        <property type="nucleotide sequence ID" value="XM_047906376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB92"/>
    <dbReference type="GeneID" id="71987106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07228"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="663"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1051"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1051"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1119" mass="123780" checksum="FDB52943EEEB9B85" modified="2023-09-13" version="1">MNTTPSSGNFSEMSPQQCFCSPRGVCSVCAAMVQGAGQGIGMYAAPSAPSDLPTAAGADMYSGAEFFDWDAAMAAQSYIGTQTLDGYRPTQGNSSLALQGAPESGYATQPLTDIDCLASPFRNHLSLPVTPAPPGPASSQTIEVPRNFHTESFPENLAQVDMGAGLHGHAVKRHEVPKSVGKRTIRDITAYDTAGQPDHKTRKLFDASEHLQFNGEQTELLEVKLQQWQKRSHLPLDKDLKNIAAACDLSPLKVALWFGAKLRLHEAPAGRVPRATDPAQPAGTTDVSAMIWKYINDAANKDCTPGKPGKLAGKFRCTWGCTYSSDSRFDWERHEESKQPQNFWACISCRGSDTGASFITHRRDKLFPHIHSMHPTEESNKDQLREKSKVQYEAPFIRHCGYTCVSTGQVCGHIFKSWKERNDHWIAHFNDDVDGPSDQPPSSRNRDVGDGGSPGDSNSNSSDGSSTATSGVSPPTQQGSNSGQSKRQRYSGGRQRVQQEAPNGVLIKAEPAQPCSARMSPPTRKVCHLTFIDIHNHELVTPDVTPKFLALDCDVEAMKVLPQKTSLKLNASTELRLPARDGAVAVMKAAIEIAMEMGFQYLWSDMISSTATSQANRKEIYEEAMLITSMGFRKDESQPIWHFTSDFKHLEKVRTWSEQRNWFRHVEALGQGAYGFVDKVKLESSGSPPETYARKIVLRDRTNKSQRARYLREIEIMQSLDHPHVARFIAAYCDRTAFNILMSPVADCDLRRFLSTPKEFEAKIQCVPQWFMSLAEALKYMHNTGLRHKDIKPANILISDNKVLLTDFGTSLRNSKTGAAALTSGGTFLTPKYSAPEVAAQKLRGLPADIFSLGCVFAEMIAIACEGSLEHLHESIGLADEGSDSDTNYNRRIPQLQAWLRSLDMTDLNASLKRAILVTVQMVNSDQTKRPLAPEIVRQLCSKEHRQAGAACELCSDQQRRADVPTAACHCCSTSLGICHGSLPHDYIVLDRLLSLRFDGSNLQKLALQEKIVFDLQINADVGNGGSQSKLNLFKQHFQQALQDQAYVDRNDDYTDDKPSVKTDRPPLRQGSSESYRAYQKRVADAYAMSLDRPDTNRANQVTANTIRGIPRFEEVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC71</accession>
    <name>A0A9Q8PC71_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha,alpha-trehalase</fullName>
            <ecNumber evidence="3">3.2.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764078.1">
        <property type="nucleotide sequence ID" value="XM_047909345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC71"/>
    <dbReference type="GeneID" id="71990075"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10197"/>
    <dbReference type="OrthoDB" id="200349at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000032">
        <property type="entry name" value="Vacuolar acid trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051:SF8">
        <property type="entry name" value="PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040379061" description="alpha,alpha-trehalase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 N-terminal" evidence="9">
        <location>
            <begin position="39"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 central catalytic" evidence="7">
        <location>
            <begin position="397"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 C-terminal" evidence="8">
        <location>
            <begin position="736"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1012" mass="111562" checksum="8F314233AFF60182" modified="2023-09-13" version="1">MLLGTLALLALASTITATIYNTRFNGTTWDDSKWILKTTHLDQGHYQSRMSLANGYLGINLAAIGPFFDYDDPVGSDNINGWPLFDRRQSFATIAGFWDSQPTTNGTNFEWLNQYGGESVISGVPHWAGLHVKVGDQLLDAKVPAEQIANFSSSLDMRNSVMRWEYIWTPNGGEAIEVKYEMFVHKLYVNQAVVRAELKAERDVNVTVIDLLDGDCAVRSTFVEKDYLATWPMIYSAVRPDGIRHSTAYIYSSLVGDDSCDLEARQRVDDPSLTGNSSSIAQSVTVALSAGKTSTVTKYVGGASGDAFEDPQEVALNASWAGVNVGFEKLLKTHVEEWKTIMPEDSVENFRDEAGALPHDENVQELAITAVTNPFQLLQNTVGDNARLAAANITKLQSNSISVCGLGSSCYAGLVFWDTEVWMQPGLVVSFPQASRQIAQYRVDRERQAHENILTAYQSSQNETGKFSPEGAVYSWTSGRFGNCTGTGPCFDYQYHLNGDIGLEFYNYWSVTGDTDYFREELFPIYESFAQLYADLVTYNDTTGLYDLYNATDPDEYANFQNNVGYTMALMASHINNTNEIRERFGMEANETWAKISSLITIPVDNDANLILEYATQNGSITVKQADIVLIDDFLQWPNPYTLSNLDYYAAAQSPDGPAMTYGVFSIVANRESPSGCAGYTYDLYGSAPYTRGPWFQFSEQIIDDWSLNGGTHPAFPFLTGVGGANRVAVFGYLGLRLNPDTLDVDPFLPPQIPQLSYRTIYWQGWPIKAYSNQTHTSLTRTGDPLTQANSTFATAAIPVIQGITGTNHFQLRPNSTITLENRQIGDIKTIPGNLAQCRPVSSEADYEPGQFPLSAVDGSVSTKWQPTLSNTTATLTVELPQPFVPITSLRFDWAQAPPSSFRVTFHNLSDTSAVPPLEVTSQQNVEISDPYNAETAFLIRPYMSNTTNVTLDTPAWSARFATLEIKGNRGTEGTSDEANGTGATVAEWAVVAAGTGEDLARRSRRAWLGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCJ2</accession>
    <name>A0A9Q8PCJ2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764334.1">
        <property type="nucleotide sequence ID" value="XM_047909752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCJ2"/>
    <dbReference type="GeneID" id="71990482"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10604"/>
    <dbReference type="OrthoDB" id="10618226at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="54236" checksum="BD8FDEEBA1D653F7" modified="2023-09-13" version="1">MAETAHPNHSSEEWLNEKLPVEVQKRISDYLELRDKLALRTVFPKTQHEFVDNALMDTVNTLYVSPSKNSLDNFKLVCSTKYYQQRVTHVVFVPKAIGDEDFREIKSFKKYREQVPALSIEDARHSFCIYRDLVTSGKRSVSLAMYDQGPTKSVVELLRDGMKKLPKLAAASVATAITHDGINANPLWYSEEFGRSKEALGHYVVEQDTASRAAVSALGSSSDDGIDSFFEALGSAKLKLESLTLGEGMARQLYSEIQICTGFDDDCLKSIFSKVKKLSVAYKDLNEHDFSYMWQHIAEIAVNLRELTLYNGAAIYDSFWRTPGDGVPVLDHFLHFGQFPKLEKLHVQGDHIKPGILNSEHFKHFLNKHRDIRSIVVQDMLFSGYAGDICADMKSVFEHARSKMSKDATFSMKVHRRDEHADGGLCTFDGRSDCDGTCEMYLVHGRTWMERSELEGLAHELKVELVDGSWDFGAYVMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCL6</accession>
    <name>A0A9Q8PCL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTP-binding protein rho2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_10629</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764380.1">
        <property type="nucleotide sequence ID" value="XM_047909777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCL6"/>
    <dbReference type="GeneID" id="71990507"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10629"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000573">
        <property type="entry name" value="RHO family GTPase Rho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="23341" checksum="BA38C806DD93E3BC" modified="2023-09-13" version="1">MAAQQDQVMRRQALIDVPRRKLVIIGDGACGKTSLLSVFTLGYFPTRYVPTVFENYVTDCRVDGKSVQLALWDTAGQEDYERLRPLAYSQAHVILIAFSVSSPDSLHNITTKWHPEVLERCPNVPIILVGLKKDLRDDPIAQEEMRKRSEKFLTPDEGEEVRKRISAKKYLECSSLSGEGVDDVFEAATRQSLLSGDHKEQGGCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCR7</accession>
    <name>A0A9Q8PCR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764398.1">
        <property type="nucleotide sequence ID" value="XM_047909250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCR7"/>
    <dbReference type="GeneID" id="71989980"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10102"/>
    <dbReference type="OrthoDB" id="3034003at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="711"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="810" mass="88923" checksum="DE5F7CE587C774E4" modified="2023-09-13" version="1">MAHGLSVAQAAALINAAFTIAKFSFPMLTSIIAIRSLKSQPNAATWSVFGRLINESLWPKFLSTDTASPRRVQKRITALAVASTAVAWILAVSVAITPLGLHETTILKQEDNALFVHAVDESAINQATRSRAAYMANRRCGSLLAVSCPGNTDNHTITVGNRTVWAGVGNQDLMSTTIADNITDAFSAATRAGGSTIAGVFDIQWRSYLNYNNATNPGNSEPWFDEGRPRTTDSFRFSQNFATQDLIQLVNGLIVSTLSDGTRGIGFRNHTIPLGSADQLGHRWEEHILWLAPETHCTNLNLSYDVSIPGPNSSRLDRQRMRVTDHGGLFDRDENYRILTLNDTQDDPKLQGRSWNAAVYTNRLLKSLLNEGYNEDHEHEPKEYPLDKYTPSELSSDQRELRQISLSRFGEFSKYYGPAPNLPLDMSMLNSRTPANKSWTESWANISSSLKNIESIDSHVLGWSGVLTNISQAGAVGGLLLGPGRRIDAGSLAEQPAAIDSHVEPGSNWTQPLYACVSAIKASVKKVRFSTNGTTIHGRLSDIQVESIIASDMPVTWGVENSGRTASWIQPLWGIVSPDASQTHDVFTLQRPELYLPTGSDSVFFTEFERGGDAAAGAKAPFQALGTIYSFDFPDSFPTLTGYANWPIAQKWAQLSRNASSVGDIINLLWVELMANAVVGTKSVLSQPDGPDLEMVTMPAWYYERSLAYDWIYAIPALIFATIYLAALILSLVLAIPKRLSFDDIRFMLNQSAAVRTMTTERFKNDGDRARAKTKKWVEELGDEIVQLPAQLKDAAAKQEQSLLSPTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD00</accession>
    <name>A0A9Q8PD00_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764531.1">
        <property type="nucleotide sequence ID" value="XM_047909551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD00"/>
    <dbReference type="GeneID" id="71990281"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10403"/>
    <dbReference type="OMA" id="YETRPGQ"/>
    <dbReference type="OrthoDB" id="5375886at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="70" mass="7352" checksum="ABE90C5FCE169587" modified="2023-09-13" version="1">MSAPNQGRQSPEPGQQKDSQIRAPATDVNHQGQEPKEGAADASKDQLKNLGSNPGGPLDKAAEEKTSKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDA6</accession>
    <name>A0A9Q8PDA6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="10">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Succinyl-CoA synthetase beta chain</fullName>
            <shortName evidence="10">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_09935</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="10"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764725.1">
        <property type="nucleotide sequence ID" value="XM_047909083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDA6"/>
    <dbReference type="GeneID" id="71989813"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09935"/>
    <dbReference type="OMA" id="ITACDEV"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="38"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="357"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO20359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="440" mass="47889" checksum="6794765AFFD454DC" modified="2023-09-13" version="1">MFKLARSSRQVASALQSFKEAPIRQQVRNLSIHEYRSAQLLDSYGIGVPRGNVAHSPKEAQEVASQIGGEDMVIKAQVLAGGRGKGHFDNGFKGGVRIVYSPREASILADQMIGHKLITKQTGERGRICNSVYIVERKFARREFYLAILMDRQSQGPVIVASSQGGMDIETVAKENPEAIITTPIDIHKGVTDDIATDIATKLGFSKQCIQPAKDTIQKLYKIFMEKDATQIEINPLSETSDHQVLCMDAKLNFDDNAEFRQKEIFSWRDPSQEDADEVKAGEQGLNFIKLDGDIGCLVNGAGLAMATMDIIKLNGGSPANFLDVGGGATPEAIKSAFDLITSDPKVTAIFVNIFGGIVRCDAIAKGLINVVESMNLRTPVIARLQGTNSEQAEKLINESGLKIFSIDDLQTAAEKSVQFSKVVKIARDIDVGVEFTLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDC1</accession>
    <name>A0A9Q8PDC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764721.1">
        <property type="nucleotide sequence ID" value="XM_047909226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDC1"/>
    <dbReference type="GeneID" id="71989956"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10078"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="32585" checksum="D2F0D5CB6B9867A9" modified="2023-09-13" version="1">MLPDPSPTLRLFSLTKVFMAHSLREAIHPFHIIVIYTNTFTTDHKGKEHAPELIFNLALDREWCDEKQTVPQPLSRQRKTMTMQARSTTNMPPTVACEQVFALPELVEKILDHVSTTPLKLFALRRVNSTFNDTINMRKYHCAMFLSPSPKLRILDFTRILLAKNLRSATYPFRIITFSPARASSKLMLRLEMEKAFCQKMLPLSVVEWFLEDMSYTKKASWQDVLICPGQLQVEIDLGGRITWQYASGRDVPLGRIIRDAVVEVQAHSHRNPMRYGLLQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDG6</accession>
    <name>A0A9Q8PDG6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10217</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764782.1">
        <property type="nucleotide sequence ID" value="XM_047909365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDG6"/>
    <dbReference type="GeneID" id="71990095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10217"/>
    <dbReference type="OrthoDB" id="1924699at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="11">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="124" mass="13399" checksum="B7DE42BBF02864BE" modified="2023-09-13" version="1">MAESAAWPVADAALTQELLDLVQQATHYRQAKKGANEATKTLNRGIAEVIVLAADTTPLAILLHLPLLCEDKNVPYVYVPSKMALGRACGVSRPVIATSITTNEASDLMGQIRSIKDKVERLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDL4</accession>
    <name>A0A9Q8PDL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phomenoic acid biosynthesis cluster-specific transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764861.1">
        <property type="nucleotide sequence ID" value="XM_047910623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDL4"/>
    <dbReference type="GeneID" id="71991353"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11475"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="478" mass="54318" checksum="68AD349B042A8973" modified="2023-09-13" version="1">MAGMAGQRKRWECRRRRRVCDMTSPACQQCEKGGIACSGYGKNKPVTFLPIGVRNRQKRGEDGKALDARHPMDRHRVCSSDLTAAQASLPRDLVRQQDVYFVNAANFLNDHRKKLFSATIFDNHIYFEDIPSAGPALPTSVWQSVTAIALLFHSNVAKPMSSERNVLRHRLLGAKHQAIQNLVDEKGTPTYYTISSISILAQTDIMCSPEPQWRRHLDALTLIHQRSLRDNKKGGLYHHLKQSVMIWLLTTITIDTTSPASDQLFSEPHLQYWRLIGSQYSDRIPPFPPFPCPHPLLSCLVRINLIRAQSDTTRLPNIGESFTTLIDEIDNFSSEEWVQSLQGHVTDHDTWLRLAEVFQVALQVYTSAALSSFSSRAFGWWTTRRESLLAGLIAKLSEFNNETVDCIVLVWPTIVTGFVAKSGPSEYRDAVRMRLLQMSGRLGYQGLLNALSTLERFWRSEKCEMWDECFERCGAYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEL1</accession>
    <name>A0A9Q8PEL1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765414.1">
        <property type="nucleotide sequence ID" value="XM_047910470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEL1"/>
    <dbReference type="GeneID" id="71991200"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11322"/>
    <dbReference type="OMA" id="DYHRMWL"/>
    <dbReference type="OrthoDB" id="5771378at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052729">
        <property type="entry name" value="Acyl/Acetyltrans_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237:SF1">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="346" mass="37881" checksum="69309CFE643F580F" modified="2023-09-13" version="1">MAAAPGPILWSNNEYEIRPAKNTDEFRDWWWSSMQTLGWGVGYYDLDTLMNPSIGYVMLLLIEKSSGKPVGHVSAVINTKSTGWVSMFVIDEKHRGKGLGRKLLKAAEADFDRCGTKIRGLDGVAEQKPTYERRKFVSSPLGKVKQLVRPSVAKVPIAESSPSGGLINICKVPRSLLAQSDEVNTGFRRPALWSDEHLFNRKDIHGVALVTREDPADLEDLRAWAVARRYAGGIKIGPVYASDKESAKAVLTATMKLATPEAIKQVEMPNSASNRWSIAEVTNEASLAAEVWGGNSEAVELFEELGWVSAGYEYYRMWHDGKAPVAQSAGGASLRGAYAMFDAATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEY7</accession>
    <name>A0A9Q8PEY7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765725.1">
        <property type="nucleotide sequence ID" value="XM_047910225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEY7"/>
    <dbReference type="GeneID" id="71990955"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11077"/>
    <dbReference type="OrthoDB" id="2163411at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
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        <location>
            <begin position="483"/>
            <end position="544"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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        </location>
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            <end position="598"/>
        </location>
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            <begin position="1"/>
            <end position="24"/>
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            <begin position="588"/>
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        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="598" mass="63496" checksum="A2EBA599960B3D5B" modified="2023-09-13" version="1">MEGQNSIRRRSSGQQHTSHMQCADQSARHTSLRHHRRRRIFRITPELAISALLASSISTTMAQNCVSLADSTACQAFRGASVSTDSSLAGLFPFLSGVTDAASFDSGLKDYINGDFTQLRYQQLIGCSNSPDNATDFYARYTTSVLCNAIVQNSIEACRLTGDSIRPLCADSCAEYAQSEQEIAASNVCGTTGNNALTQIRADFTNCALPANSITGSCIQASTNQPNECGYTNNLGGLCSYCSASSPNATDSCCVFSKTTDRCEGVSLPIVATASLQPITVTTSATGVPTAGSSNNGGASSNNNSLSKGAIAGIVIGSILGAALLLGLIIVGCVLFRKRRSNSPATSVFNQPSPGRSPQMAFHDGTRDIHSNDRPGMAILGGGRVARMSALEGSSSSHNEVPYILGAYNDKSEEEATPESRLAPPFKRSGSLSSGSQLGTGLGVTEQQDTSPSSGADYTSPESQGQSEQLNFFKDYYSQDEIHPGDLVATLWAYEPRADDEFQLERGDMVKLLGIWDDGWATGVRVRQKAEHWLPEDKTQRDSGLTEVPHPPTSDNEGEVVKAFPLVCVCLPQHWRKTIEGSDSTEGSGPGGFPDRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF30</accession>
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        <submittedName>
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    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO21256.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="451" mass="48091" checksum="E5749AA6E8964A65" modified="2023-09-13" version="1">MAQIDEKVKSLIEKSYPQAKDASEDPAKLSSAIFSSVEYSSAEKAEIEQWLITSSHIADSSQDSAKTAERLSHLNTHLSSKTTLLGAKPSVADVALYARLAPVVKSWTHEQRTGEQGYHHIVRYLDFVQNAPLFDLKLSDSDKVDIDPSNVAAKIKPIDAKAEKERKKKEKAAAAAAAAGADNAAAAGGTVTTAASEDVKKAENNKPKKEKAKDAGDAVAAAVGSAVPTEKKEKPKKEKQPKPPKNAPAPDKPFSPSLIDLRVGHILKAEKHPNADSLYVSTIACGDEPGTDNTSEYEGKVVRTVCSGLAGLVPLEEMQGRKIVAVCNLKPVTMRGIKSAAMVLAASPRLAEGEVDNHAGPVELVNPPADAEAGERVYFEGFEGEPDAVLNPKKKVWEDNQVGFTTTADKVVAFEPTKVEKLKDSGKTEVAQLRTKQGTCSVKTLTGATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGK5</accession>
    <name>A0A9Q8PGK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1750-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766491.1">
        <property type="nucleotide sequence ID" value="XM_047908239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGK5"/>
    <dbReference type="GeneID" id="71988969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09091"/>
    <dbReference type="OMA" id="RKEFMLH"/>
    <dbReference type="OrthoDB" id="5321006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051647">
        <property type="entry name" value="Mediator_comp_sub12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013859">
        <property type="entry name" value="Ssr4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046464">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007:SF8">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20497">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08549">
        <property type="entry name" value="SWI-SNF_Ssr4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 C-terminal" evidence="3">
        <location>
            <begin position="259"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="639"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="732" mass="80474" checksum="90A865439DB0E5DC" modified="2023-09-13" version="1">MNDPSQGVAGPLQAHVHLVSLHRFPLIASLNLEQAFRYLLDAPSIVKQIAPMSWNYVQPPQDGTVWLEWISQHKNDQPYPSDGYVWGDPEQAYRQSFGGYTIEMRVHTVGFRQGYDQMATHARTRYHFVAKDPTVSASMPDTSLWLVHYHQADQSRFMPSNQVPTTPQIQQTMAQRRWLESQGRLERRDFMLHDRDHWPTLNVPGQMQQSAQYGSMAMQNRYPQQHAAQAGREPAPKRPRTQGPGMPGSSDGPPDTSIEIEEDTALGDFFDHLTQRDISVARYSQHHRWMEEVFSSPYATSQIVPPDLGMGLMGELKGLTDGILDPPSLDFKEVTEKPKKAPEPQPFTNLKKEQVEEFGKRVQKHLEAGQAEIERMKAEHAAKMQDWKKVKSLMQAEKRLRHAMWDEQEDAVPVFRLEMPAANGNAEENLRQEKVDDVVKEVESLLKVKVTSSEGATRIARGGFRERKQPEYNEQTMQQDNAINGLINDQQQTSTTTSTPGANGMSAMQQQGSAIATPQTGDQQNLNVSAQARAFQQQTSNQPTPNTMGSGHDSHDQNDASSNALGDMTGMDMGDTLMDGMDLDVDHGDMVDFGDDNGDDLGQGNDSSMPQANLEAPGAETDAISAQPSATGIPSNLGQDTAQQQQTQPQQQQTGISQDGFGGGLSDTGDNSMFNDNTFDDLANLDGNDDGLIDFEGGGMGMDDSAFGDALHGMDDGAGSGNGSTPATGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHU2</accession>
    <name>A0A9Q8PHU2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767157.1">
        <property type="nucleotide sequence ID" value="XM_047911083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHU2"/>
    <dbReference type="GeneID" id="71991813"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11935"/>
    <dbReference type="OMA" id="WRADTHI"/>
    <dbReference type="OrthoDB" id="10512930at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="667" mass="75394" checksum="0A4FB74D6FD48E85" modified="2023-09-13" version="1">MSLIDPNLVPPRTTSLLHTYLFDTTTTMIRSFDSGEWQVQTNVLRRSQSVTGLRQKQRHATRLSRMGSLDDIARHVEMWGNKHDTISAIAEHGWFDVEGEEDEDETSGRPSREQESVALLPPEIPRKNSKRRKVERRRGVSNLPKLLERYCTKEEPKYDIFGKHLQSERAYSQNKNLGFQYTTPGLEEAPVVRTVLDQNQQEAIERFRSPPPPADFGIEGRAAGQVRRARQNTNAKHAPKDPLCRDFAQGAGRSGKSKARGAEALFDALLASKRINHTPGSAISAVHEAQQETLDLARAAENPVATAKQIDHAAAEALSAKHDQPQSFFEQGTSVKTALLAKVKSFRKHQAQGREPDRNPSICRLKSKALTLKLKQSLSIHRHPHAKPCEKTRAQAEAQGQATAHAKLQAKARALEFEAEKDKLLHEIHVARRLKHQRWLEAESEMARAQDRPPNPIPPMQPISLHDDLQSDAQIHATSLDAAFDSTPTTKWRANSQLTTITTSKRNGNIRITSPPNHGILCLCNMWLDQGHTLREKALQHMTLIQQGHFPPDHLRSGCDCYLYRIYEAFTNNHFQYIGIAQTQKEQAEEYGKGRWVIYLAKETPISKLLLGSQLPSTKVRRVPARRPTSANRPRPLSARIMNQVRRRSMHGLVYFANNPLRDVRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHU9</accession>
    <name>A0A9Q8PHU9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">5-methylphenazine-1-carboxylate 1-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12109</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767119.1">
        <property type="nucleotide sequence ID" value="XM_047911257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHU9"/>
    <dbReference type="GeneID" id="71991987"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12109"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF268">
        <property type="entry name" value="5-METHYLPHENAZINE-1-CARBOXYLATE 1-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="350" mass="39095" checksum="E33023152D34EDE3" modified="2023-09-13" version="1">MLLLEAVRERLGVERVHLNHSLDSFEQDEPTSSPVTLTFAQKKSGAPSSTPTFTSDLVIAADGINSTVRRHLYLSEGPPNFSGRILWRGCLEREAFLTSASMIWSGHANQKFIAYPIMKYSDRSKSLVNWIAELRVRDEDDPDTTPPEKADWLNTVPKEKFAPKFREWTFGFLNVPDLIEKTERVYEYPMCDRTPVERWSFGRLTLLGDAAHPMYPIGSNGASQAILDAACLTRCLWDCKDLASIPQALKEYQDERLPTTAKIVMANRGNGPDHVMQVAYERAPNGFKHINDVIPQHELQGIGLAYKAIAGFEIEKVNEQAGKTEGTAEKLGLKSPRAWTTVATNSVNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHV1</accession>
    <name>A0A9Q8PHV1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767068.1">
        <property type="nucleotide sequence ID" value="XM_047911645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHV1"/>
    <dbReference type="GeneID" id="71992375"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12497"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="27034" checksum="448798E0B3FB09FD" modified="2023-09-13" version="1">MESSLPTRSSLHQGTEVPAMVPSGLLSLPAELRLDIYDLVYHQPHEQPVDLCQADPPLKSLPLTCRQLYLEASGIYQHNYRKFWSGSDFIIDRRTPEVAAIARQRVSELKENDLQKIRTLKVLSLKKDRVEDELTTSTHVDTRGLWIHSLESSARPKGNWYVLHERQSPGGPRNVRTDVAFMMIDEDNYNDDSVKERTGMEMLGSPGFRACPMWEQIIEVLYVHEDWTEVEKVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIB3</accession>
    <name>A0A9Q8PIB3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767317.1">
        <property type="nucleotide sequence ID" value="XM_047911551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIB3"/>
    <dbReference type="GeneID" id="71992281"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12403"/>
    <dbReference type="OMA" id="EGRWCRD"/>
    <dbReference type="OrthoDB" id="5382128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054491">
        <property type="entry name" value="MGH1-like_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22422">
        <property type="entry name" value="MGH1-like_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="664"/>
        </location>
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        <location>
            <begin position="520"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="664" mass="75405" checksum="86F0B1626BAB4AAC" modified="2023-09-13" version="1">MYRRALTVATAALAGRLALAGPLTKRALDTDSLANKYFGNDADWYRERIPYFESSDKEIEAVFYYRWKIFRAHQRDLGERGYVSTEFLDDVGWQLEPWATLNDATGFHLGEGRWLRDRRFADDYIRHMYNGGNDRHFTDYMSDSVYGRYLVDGDVDSMTVHLDAMTSLYSQWEGDSFDTSKGLFWREPLADATEYTISSIDASCGEDGFGGGQAFRPSINSYQWANAIANAKIAELAGRGDVASTYNQKAATLKERFDADIWNQTMEHYIDRHQRDTECVKYYEPIRGRELVGLVPWMFNMPDNNDTYSQAWKHLLNPEELRGSSGMRTVEPSYEYYMRQYRYDTPTGLRECQWNGPVWPYQTTQVLLGLANLLDTYDQDIISKSDYLDELRRYTKLHYQGDLLDLEEDYEPDKPGPIVGLPRSHHYFHSGYNDLIIGGLVGIRPQPDNSIIINPMIPTNSDISYFRLQDVPYHGHTIAVQWRSGTLQLEVDGNVVASSQGLNKLTAQIASAPAPAIKRPIAKSVQLVRGQFPIGSASSGNETENVHDAIDGRVWFFPELKNGWDSDATDADSEQFYQVDFGSDTSFTSVELAFFADDGDYVLPSEYKLQQNDGGSWSDIWTTPELIANGVTTIAGDAVETSQLRVSFTQLAGKRTRLAEFKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PII6</accession>
    <name>A0A9Q8PII6_PASFU</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PII6"/>
    <dbReference type="GeneID" id="71991941"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12063"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="20820" checksum="65D6D2ED16D28573" modified="2023-09-13" version="1">MSFDSAVFKSSQADRAVKRFEYVAALLCGPENMSSTLLSLATASFEDLAQIWSWNATVPEAVDSRIHDILLPSIRSRPEAVAIQAWDGNVTYAQLVQDVRSIRPNQKIGCGTSSRSPPRSAAQAGVAQTLASDDVGIFVVSEASLGALDFTVHPSMSSCRMAAQKTYYMFYIHFRHNGQAQGWAGHTSQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIK2</accession>
    <name>A0A9Q8PIK2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIK2"/>
    <dbReference type="GeneID" id="71992233"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12355"/>
    <dbReference type="OrthoDB" id="3650892at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047126">
        <property type="entry name" value="RNF141-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109">
        <property type="entry name" value="RING FINGER PROTEIN 141-RELATED"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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            <begin position="90"/>
            <end position="116"/>
        </location>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="261" mass="30370" checksum="B3D69658F2EA2C41" modified="2023-09-13" version="1">MPLASRKDFLSTLTPPQCPICYEHLTAPITTPCEHTFCLECAKTWLKTAATCPSCRTVLYDIDLDDEEPENDSELQLPLEPGYVQRAFPSTTAANDSGIPAEHDTSGTDPAPPHPRRLLSRLPRLHRPIQHREAALEERRLSRQRWQRSMDRLFRTLQKAHRSLELRRRVYDRQQTEMLEVAEILRHQIQLQDDMHAEIVRLAEEHENSLREREVKVEEQLRELQGGEARRLRVSRSAMDAAGEDSKWSWARMKERLIAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIK6</accession>
    <name>A0A9Q8PIK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_12290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIK6"/>
    <dbReference type="GeneID" id="71992168"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12290"/>
    <dbReference type="OMA" id="GSWHVSW"/>
    <dbReference type="OrthoDB" id="5344482at2759"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="273"/>
        </location>
    </feature>
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        <location>
            <begin position="285"/>
            <end position="379"/>
        </location>
    </feature>
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        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="393" mass="42010" checksum="F65DE9E52D9F3896" modified="2023-09-13" version="1">MADASQSARPVSDPVDTSFDPAAHVARDDVESPSLTSGNALARFEFEPGRSRDGTKVLMVEWEEDESTKGVAGDWEISWEGKRTVLPARDQSPGEEAPINRLYFLLGPGVNIPTAVRLQKGSIVWRTNPLPAIFSPELGATARQAGKKGVLHTIWAKKRLQVLNTEIEQESKENVEGIGLEMAAAEKEWIEQNFGVATKPSSISIDTRPAMASIMGQGSLNSPTSPRSPGGGRLMDKLKGLKLGTTTSDLLRKDSSSVDAGLPAGYQNPLSPEQTDVAVGSFGSFAALKGAPPPSTMGAKPPQPPAQQQPRKIAAQRPPEAFAAQQRQHVSMGSLNAFASGDVPANPNPEQEDDEDDLFALPMSPRSPEMSKSPFSFAAQDTVKYLKGERASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJN9</accession>
    <name>A0A9Q8PJN9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768037.1">
        <property type="nucleotide sequence ID" value="XM_047912219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJN9"/>
    <dbReference type="GeneID" id="71992949"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13071"/>
    <dbReference type="OrthoDB" id="10387329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="124" mass="13508" checksum="CD08FE16477EB233" modified="2023-09-13" version="1">MTTPTINYKGMTESYSIFYIEILIPDGFGSGDAYALLLDLVCKLYSHNPKVLLREVDDLPYGAPRAFFCGVPERGAWPGNGIAGLGLEEDGEEKVRVRKIWPLGEGQGGGGEDVDKVEEGKRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK43</accession>
    <name>A0A9Q8PK43_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768277.1">
        <property type="nucleotide sequence ID" value="XM_047911851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK43"/>
    <dbReference type="GeneID" id="71992581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12703"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="75" mass="8584" checksum="89B3D2427D2C2AB5" modified="2023-09-13" version="1">MASPRGLSKLPTELRLMIYQYLITERKIVTSTPWFWVPVFKSVDTYIDIVSVLNLIITHPELGPEIADLRPLISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLG2</accession>
    <name>A0A9Q8PLG2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Nucleoporin NDC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_13674</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NDC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768982.1">
        <property type="nucleotide sequence ID" value="XM_047912822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLG2"/>
    <dbReference type="GeneID" id="71993552"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13674"/>
    <dbReference type="OrthoDB" id="67850at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106166">
        <property type="term" value="F:spindle pole body-nuclear membrane anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:spindle pole body localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019049">
        <property type="entry name" value="Nucleoporin_prot_Ndc1/Nup"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269:SF6">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09531">
        <property type="entry name" value="Ndc1_Nup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
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    <keyword evidence="10" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
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        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="686"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005760"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO24616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="736" mass="81939" checksum="4465437549587084" modified="2023-09-13" version="1">MPRQYHANMATQTTTLQQTILAPGAAATGATPTERTRFYKEFLTPALHRRFIKAVGILLAVCYVFGIIITSFRGTIVTAWFPLGPAGARASLLLITCLSILVVRVANMHIGERITSSVAETAYDLVWRRLGKSLHTVGWYALSGWLFGEFYVWTRGDSAELGLVLPYESYERPRLNENPIFLRSLFIVLGVLQAGLHLVKDYDCVKIPATPREEREKEEEAKKNALTRILSPEAVARLPAVVRTLADKLGPIVHGAVNITIITVIAHLFIYFLVLRRPLWSFFYSMARTWFQLPSSAPPPGISDLHIWALFRQTLTAPLALSILWEISNTIFSVFVAQAPILKDAPLTSGVKDARGVVLRKSKDPNSSLLNGLKTKRELNKTFAFWELYLIATKYDDRRKTIYTEVARKDGSTWSQICDIALKEVEAITARIQAATVPEQKPVVREEQPLQRLTEDDLGTPKPEKRGLPKIADREVAGDGDVFAKKAPDLVQTFGNFARSVGQSANTQNPITPTALKYIEYGADQLIPKETQQRLSRSHMQEEANGFFAKVLRSPIGEAFKNTFARQVKKVVFGSPTSNKANIVFAVKSLTELGVKSLSEDDYGQVQKDIPRIIRTFTTTIKNIETYTRTLKPNWTDLGFTEQDRQVAEVQELLEILKTSLKQIMLQFGEYANTLGLSKKEVREAGEATGDTPAPVALIGGRPTRPNDGAFERPEMQQVGNDGGIGAGGRLRRTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLH4</accession>
    <name>A0A9Q8PLH4_PASFU</name>
    <protein>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_13416</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLH4"/>
    <dbReference type="GeneID" id="71993294"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13416"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="34657" checksum="EEF3CEFF7A2CA7C0" modified="2023-09-13" version="1">MSGLEAVQNQTCAPVECNLTEASAEADHASSESTSTPQDDYASWKSTPALQGWYHQTAPPRTVRPALPATAQRYIQLLEYILSDGERVQEARHLLSAPDAPSRKRTKARDDLRSHLRRLNTHVGDITRIVEAERASTGSTILPGHVASTLEQNQAAVARLQELVVSQRDVDQELASVQEHIRHAETRQAGRRFASTKVLIEKFKSSERRLQQQKSAFEACWRDMDGHAKRTLSAIKDLIKLQATNTTSTGKEPYDLRDLRPVAQPIDLDPSQQEKIRQDWEDAKHNLAASAVIYDACINEREHSLRNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM58</accession>
    <name>A0A9Q8PM58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rab guanine nucleotide exchange factor sec2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769285.1">
        <property type="nucleotide sequence ID" value="XM_047913558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM58"/>
    <dbReference type="GeneID" id="71994288"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14410"/>
    <dbReference type="OrthoDB" id="1748564at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="65"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="498"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="72"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="657" mass="72451" checksum="7D1EA1FEE256A1ED" modified="2023-09-13" version="1">MAAVASPQNQPISAMRDEVTDTRTPSPVHRTDSSDSETREPVYQPDLSAEVAMLSTKLVNAINYQTNLDDSLQQSRHELEQQRQRCTTLEEEKRRVDQLITSGALVRKSETDKIILKLRQELNSEKTAREIAERDKKKVEGELENLTSALFEEANNMVAAARKDTEAVEKRNAQLRSQLQDTEMLLASQQEQLQDLKATMEKQHEATMCRVPSMPSTPITTQGATFDALQISPTDSSLPDIPPEHPLHFVQLISPVLRSDTSAYTDFQDLLLLARRLGAHSRTNSSTATQTASGGSIAANQLASASSPNLPGAFSFSTNSSPSSFATSGTLPPLKDSKFYKRVLTEDIEPCLRLDLAPGLSFLSRRTVLGALLQGTLAVEPYPQNKHYFACTLCGESRRNEPYVRKYRFRTSEDDGVSKPLCDYCVARLRSTCDFVGFLRMIRDGHWRTDSGEDQKSAWEESVRLRERMFWTRLGGGVVPAQQLRTVPPTLSSAVDARHSLESIPEAQVKSVETSDGTSDVFQGHPDRPKSAVGSAIVDMSSTAAASAAPELRPQPSSQRSNDDKDDTTKEASTEDSERSPSEDIMKSLRDSTQALSVEKETTPRTSLQVPAPEPEASPRTSLTVEQSHQPERRGSSVLARVRAMESQGKSLPGAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMI7</accession>
    <name>A0A9Q8PMI7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_14233</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769480.1">
        <property type="nucleotide sequence ID" value="XM_047913381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMI7"/>
    <dbReference type="GeneID" id="71994111"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14233"/>
    <dbReference type="OrthoDB" id="10251642at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000002">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.210:FF:000001">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000017">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000006">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000005">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.210">
        <property type="entry name" value="FACT complex subunit Spt16p/Cdc68p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029148">
        <property type="entry name" value="FACT-SPT16_Nlobe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056595">
        <property type="entry name" value="Fact-SPT16_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048969">
        <property type="entry name" value="FACT_SPT16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013953">
        <property type="entry name" value="FACT_SPT16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980">
        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980:SF15">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14826">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24824">
        <property type="entry name" value="PH_SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08644">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21091">
        <property type="entry name" value="SPT16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01285">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01286">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FACT complex subunit SPT16 N-terminal lobe" evidence="14">
        <location>
            <begin position="7"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="FACT complex subunit SPT16 middle" evidence="15">
        <location>
            <begin position="543"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="16">
        <location>
            <begin position="815"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="439"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="755"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="930"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="615"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="481"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="936"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="996"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1016"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO25114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1027" mass="115952" checksum="EFD632E99B0C0B5A" modified="2023-09-13" version="1">MAEEVSIDKAAFHNRLSGLITQWKADKRSGNSVFGDVGSIAVCMGKSDESQGFHKANGLQFWLLGYEFPATLFVITMEAMYIVTTKKKATYLEALKDGKTPVEIIVRGKDAEENAKQFEKINETIKNAGKKVGTITKESSTGPFMAEWKTAFAEISKDVEEFDVSVALSTVMAVKDENELKAIRNAASASAYVMKDYFVETMSDILDKEKKITHKAFSDKVANKLDDEKFFRALKGVGKFDAMQLDWSVSPTVQSGGNFDLKLATEPDDNNLHQPGVIISALGLRYQTYASMIARTYLVEPNKTQESMYKLLLTVHDTVIKELREGVQAKDVYNKAVAVVKAKKPELVDNFFKSVGAGIGIEAKDNTLNLNAKNTRQLKDGMTFSITTGFSNLENPTAKDKKRDGTYSLLLSDTVRVTSSSEAYCFTKDAPRDMESASFFFNDDEEEEKKPKPKKDARVGAVAQSNITKHRLRGQGGVTQNEEKEAARREHQKELHAKKQSDGLEKYTEGHGNLNGTEEKKFKRFESYKRDNQLPSKVKDLTVMVDQKASTVILPIMGRPVPFHINTIKNATTSTEGGFCYLRINFLSPGQGVGRKDDQPFEDPSAQFIRSLTFRSQSNQRMEDIQNQITDMKKAANRKEQEKKDMEDVVEQDKLVEIRNRRPYRLDNIYMRPAVESKRVGGSVEIHQNGLRYNHMGSQRIDVLFSNIKHLFFQPCVGELIVIIHIHLINPIIIGKRKTKDVQFYREATEMQFDETGNRKRKHRYGDEEEFEAEQEEKRRRAQLDKEFKNFAEKISDAGKNEGLQVDIPFRDLGFNGVPSRSSVTIQPTTDCLIQVTEPPFMVITLNDIEIVHLERVQFGLKQFDMVIVYKDFTKPPTHINTIPVESLDSVRDWLDSVDIPFTEGPLNLNWATIMKTVIQDPHTFFADGGWSFLGDESDNEGSEEESEESAFEVSEEELASASESEDESDFDDDASADASDEEVSEEDEGEDWDELEKKAARKDRDGGLEDEDSRKKKAPAKAKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ69</accession>
    <name>A0A9Q8UQ69_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762946.1">
        <property type="nucleotide sequence ID" value="XM_047906332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQ69"/>
    <dbReference type="GeneID" id="71987062"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07184"/>
    <dbReference type="OrthoDB" id="3644624at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14566" checksum="545F9FC6C634CE95" modified="2023-09-13" version="1">MGDGFLEPDTAPEQRSVWKDINRKVLKRTTLALFKKQHVVGRQTYAMPFQRMYDPSYSLPLNVEMGLAGDFAFIAACEPQVAFVTAAAIEQTEDEPSLLVKLAANEGIAVIVREKSNQLFEVLRQHAKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQM6</accession>
    <name>A0A9Q8UQM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="17">RNA-binding post-transcriptional regulator cip2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_06686</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulates global gene expression after oxidative stress. Interacts and stabilizes mRNAs and may regulate their transition between different cytoplasmic components after oxidative stress.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with csx1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763259.1">
        <property type="nucleotide sequence ID" value="XM_047905834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQM6"/>
    <dbReference type="GeneID" id="71986564"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06686"/>
    <dbReference type="OMA" id="GMQRDDS"/>
    <dbReference type="OrthoDB" id="434258at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02639">
        <property type="entry name" value="R3H_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12253">
        <property type="entry name" value="RRM_PIN4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.50:FF:000002">
        <property type="entry name" value="Immunoglobulin mu DNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000183">
        <property type="entry name" value="R3H domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034186">
        <property type="entry name" value="PIN4-like_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034069">
        <property type="entry name" value="R3H_Cip2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="162"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="16">
        <location>
            <begin position="321"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="248"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="531"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="598"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00062407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO18893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="620" mass="68018" checksum="75B6CE50BEB87AE2" modified="2023-09-13" version="1">MNNQHFDMYYDGPPNRSPTSQRQNSLHRQNSRQQFEAYGHLPSGLYTAEDHAQANFNGGNRFNPNDMRNATVGGYSNGYDMGGQQSWNSGAFGQNNTLNGLGGTQGLRKPPSRGGRSGIPSAWLDQNQQMPMNPYANGLGGMGGPQYGRQEISEPDEELIPTAIVIKNIPFAIKKEQLVGIMTDMGLPLPYAFNYHFDNGVFRGLAFANFTNPEETATVIDSMNHFELNGRKLRVEYKKMLPAAERERIEREKRERRGQLEEQHRPMAPQTLQTQASASSLSSRMMAGSPSPVSARNQTARNGLPSSFPDPSAGVEVDLNDPAALQHYSKLLLFKEDTARNLLVFSPTLSPPERRIVHTLAHHMGLGHASKGESDRRAVHVFKEGHQRLSPPMPSIQNLQGDQRRALNRAATTDFSDVRANEAYYGAPNLRHQASGYLGYHDSPHGLAAGSNLRSAKSFADLRSYTPSPVPSTASFPAALSNNVARLQQDFGRDSAQSNTPTLMTPTSGLAERGDTNNIINGLGNMNLGQGFGGSPRGLRGFPSWDRDTPGPIGSNRSFSTNYDDRSQSRSNMQGGPERQPRGPLPERGAGFPRRQNGHVQRNSDELSQQSSAAEITVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQM7</accession>
    <name>A0A9Q8UQM7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763203.1">
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
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        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="582" mass="64692" checksum="A61B5373423B49F3" modified="2023-09-13" version="1">MSEIHSTIRPNTFLFLRLPTETLRLMEIKLNTIIDVGKIGSFPSNLLIGRPYHHTYELLEKREGEQYSRLRIVSQAELNAEAGLGDAVTPSESRAEPATPTATATEALPESYDLLADDGSVLMKNNRLTIDDATRQKLTHQEIEDLKKSAGSKEVIERILANHAGLDEKTAYSKAKYTLRKHKKYLKRFVAMPMDLQSLMEYVLEKEAARIMEIREESLGLVGSWSNAHYSGTDGLNTGGNEKDLGGRWLVCDDTGGLLTAALAERMNLLHLPQKEEAHEPTADVTMAEAPQTNGDAKTTRPAHKDFPIPATTNTITVLHPAVQPNLSLLKYFGYDTSNPNAMQESDRPLHTHLKPLSWLQLLHPNEDPTYTEPEVVSDATLATWKSGKRGTYYKKRRRWERCRTIVDETREGGFEGLVIASHMDAVTILEHAIPLVRGGGHVVIYSPTIEPLVKIVDLYSKERRSAYIAHISKGETPTKDDFPLDPRLLLAPSVQTSRVRGWQVLPGRTHPLMTSRGGAEGFVFTARRVIPLEGGVEARGNFGSKKRKTEKQAMEIDDKVAQASPAPVNALFNTAEEAAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR30</accession>
    <name>A0A9Q8UR30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR30"/>
    <dbReference type="GeneID" id="71986614"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06736"/>
    <dbReference type="OrthoDB" id="3643441at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040322466" evidence="1">
        <location>
            <begin position="17"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="178" mass="19165" checksum="C78211E13A783B51" modified="2023-09-13" version="1">MYLPTIIALLSYLTFAATTPSKRQSCAAEQKIAACKQEIATIRSHNFEDANKIPLTLLASRTFIITYGNLPVLPAELGFQLPPVNVGVTDSTVCLELVGLATVLDAGVPEGSDSYIVNSNGTVTSDFIQTDRLVLQAVHVREIHEFDESTCRISKILGYVNGSLLGREAGFGIPPLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR57</accession>
    <name>A0A9Q8UR57_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR57"/>
    <dbReference type="GeneID" id="71987498"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07620"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="316" mass="35414" checksum="09FC568D171263B6" modified="2023-09-13" version="1">MDNIQEEAPPNYFDLDAWEAYQSRIFFAHTANNLALLAYAGMFGLILTGLGMTGRLGAPDTEVAEVNEAGLYLLLGFLLFGTMMGLWLIARDDRGNLSVQRTFQRALKSLMGDNTGRRSLYPTRKLFTGNDENGDKNSWSLFVNTPRRYINIKIEVEIANIHRRYINIEIEPEDTNIHLKQQFHAESNAMDDGIYPLIDRIPDINAGSSGNNGILRDPDRFGSHMNPNIPYRPGAESPKSDDVPPPEPIDPDMILGPDRDSKDGCRRACMRGCNRGCVKWVLGVFGFLCFTAAVAVIAVYSHRAFKKSYEGEPSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URR3</accession>
    <name>A0A9Q8URR3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764371.1">
        <property type="nucleotide sequence ID" value="XM_047909746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URR3"/>
    <dbReference type="GeneID" id="71990476"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10598"/>
    <dbReference type="OrthoDB" id="5595109at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="532" mass="58029" checksum="5F7BCBEF5D52A8A0" modified="2023-09-13" version="1">MRSSLSRTARQLSRNANRSIVPSCRVSGVRWSSTDDGHKWSTPLAKQLAEAITTTGPLPVASYMRQVLTSDLGGYYTGALGSDRDPFGAKGDFVTSPEISQIFGELVGLWVVAEWIAQGRKSEGVYLMEVGPGRGTLMDDMLRTIRNFPPLAKAIEAVYLVEASEPLRQAQHKLLCGDNPFEKSELGWQSISRHSPDLKIIWTEDVRFVPREANKTPFIIAHEFFDALPIHIFQVTKTTSADQDRPIQTPTGPIKAQRNQAPGSQWRELLVSPRPPHRLKEGEPEFELSLSRTQTPHSMYLPETSPRYTALKETDGATIEISPESQAYVRDFAIRLGGSNPEDLAAASKPTAVIPGREVPAGPQEVPLQKSDPSGAAIIIDYGPPATIPVNSLRGIRAHKRVSPFGAAGATDVSADVDFMALAETAINSSPGVEVHGPVDQARFLTAMGIEERAAQLVKKAVDKERSGSTGKDKGELTDLVKRIESGWKRLVHISPQGMGRLYQVLAIVPHKPPVEGQPRRRPVGFGGDVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USP2</accession>
    <name>A0A9Q8USP2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765405.1">
        <property type="nucleotide sequence ID" value="XM_047909953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USP2"/>
    <dbReference type="GeneID" id="71990683"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10805"/>
    <dbReference type="OrthoDB" id="10535546at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040253233" evidence="1">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18483" checksum="FEDE7DA1908827EE" modified="2023-09-13" version="1">MNFLTKVTALLLPLLPCALAQAITSSSFYLVIEQPGATRDNTTLYSCPTAGHYSALCPDYLNPVMNRNSTTFHLNSTSIDPASEFLTVDVVDENMDYIESKALVFAYGPTTNVATPLFTSADVKEYTKLITATTVYFDDSEHLGIRSNYDDSVDPAVLGHWVAYYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USW7</accession>
    <name>A0A9Q8USW7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">O-acetyl-L-homoserine sulfhydrylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765599.1">
        <property type="nucleotide sequence ID" value="XM_047910319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USW7"/>
    <dbReference type="GeneID" id="71991049"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11171"/>
    <dbReference type="OMA" id="QFKNTEH"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004650">
        <property type="entry name" value="PRK05994.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="64078" checksum="0AB8B6CC62102A39" modified="2023-09-13" version="1">MEAIPYSDAKLRRILSTVRTIAIVGASSNWNRPSYFVMKYLQRKGYRVIPVNPGNAGKKLLGEQVYANLREVPDKVDMVNVFRASHTVGPIMEDAIAVGIKVVWMQLGVRNDEAAAKGEAAGIEVIMNRCPKIEFGRLGGELSWGGVNTGIIRNKPAQAPTNNRLRDLPAVNIEHGFETRAIHAGAAPDPTTGARGTPIFQTTAYVFDDVEHAASLFNLHNFGFIYSRLTNPTVSVLEERVASLEGGRAAVAAASGHAAQFLIFATLMEPGDEFVASNKLYGGSLTQFGLTFKKLGWHCHFVDPTDPENFRRALTPKCKAVFIESLANPGGIIADISAIAEVAHSAGLPLIVDNTLATPYLCRPIGWGADIVVHSTTKFLGGHGNAMGGIVVESGKFDWTQGGKFPSMTEPEPAYHGLRFYENFGDFAFTTKARAVALRDYGPAMAPMNAFLTITGIETLHLRMERHCHNARAVADYLAHDSRVAWVSYAGLDTSPFRALAKKYLPKGSGAVFTFGVKGGYETGCKIVESVSLFSHLANVGDTRSLILHPASTTHRQLSDEQREAAGAGADVIRLSIGLETAADLIADLDRALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT63</accession>
    <name>A0A9Q8UT63_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765826.1">
        <property type="nucleotide sequence ID" value="XM_047908655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT63"/>
    <dbReference type="GeneID" id="71989385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09507"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="32631" checksum="AA811F773C0A727D" modified="2023-09-13" version="1">MDTIGPNIAFGIDQEPAVALCSSQVLVEFEHSAPASSSTGPDENIMAFAGKVVDAGSAVSAFHNADRVVVFDKPSSFQQNLTATHRKIIVPSERLHIIPETMSSYVACLHAAALVQATVIIEQKLHLSFSPEQKKPHRGQVPQGRRVAIIGGETELAVALVQVLRRVSPNTRIVVFSSMDNQADLFQRTCHLVGLGASFAIDGALPDLMEHAEAMKDEAGIEVIINTVIGQPVRTDLVDVLTGPKVLVEYQSLRIPTMQSTARVGDSDFSAALYRMLAESADEFARYVQSPDRCIPQDDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT97</accession>
    <name>A0A9Q8UT97_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptide transporter ptr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08983</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765948.1">
        <property type="nucleotide sequence ID" value="XM_047908131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT97"/>
    <dbReference type="GeneID" id="71988861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08983"/>
    <dbReference type="OMA" id="DSYMGNV"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="500"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="622" mass="68785" checksum="E6E8BE8295C6D556" modified="2023-09-13" version="1">MSANLDQDLAVMAQARRPSVADEKAAVYSEKGVSSLDDGSRTTPGRDGDEPTMEEMKTLRRISGKIPWTAYTVTFVEFCERFSYYGTTAVFVNFIQQPRPFGSRAGNIMNNETCFNAPGWDRDACLQPGGLGQDQRASTGLTTFNQFWAYVMPLVGGYIADTYLGRYMTIQWSILAAIIGHTVLIVSSIPTVMDNPNGALGCFAVGLVIMGCGTGGFKSNISPLLAEQIPETRPRILTTKTGERVIVDPQVTYSRVFLYFYMMINAGSLVGGIGMVYAERFIGFWLSYALPTFMFFLAPIVLIGCKKFYKLAPPTESVLSKSFKTLSLASKGCWSANPIQTYRNFQRDDFWEKVKPSKLGDSAPAWLQGVDDVWIDQVARGFNACKVFTWLPLYWLAYNQMVGNLTSMSATMQLNGVPNDLINNLNPLTLVIFIPIFDGLIYPAIRKTGFNFTPIKRITWGFFLASMAMVSATVIQYYIYQKSPCDSTEVNSGVGCEAPINVWVQAMPYCLVAFSEIFASVTGLEYAFSKAPENMRGLVMGVNLVQTAFSAAIGQALVPLAEDPLLVWNYTVTAILAFLGGVGFWFTWRSLDAREDELNLIEETKYKGRGAAARASMDVERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTT1</accession>
    <name>A0A9Q8UTT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor ecdB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766473.1">
        <property type="nucleotide sequence ID" value="XM_047908926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTT1"/>
    <dbReference type="GeneID" id="71989656"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09778"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000008">
        <property type="entry name" value="C6 zinc finger domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="626" mass="69672" checksum="EAAA7CF8E0DAC16F" modified="2023-09-13" version="1">MDNVNPRTALDNATRMAQLQQYEEEDGRPALKRARSSMSKPSASKAPVQESIAFDIQNAGDPLDYPRRRATIACEVCRSRKSRCDGARPKCKLCTELSADCVYREPGIKLDAGDKLILERLAHIEGLLQSNLLQSPTSGSGPFGPISPATSNTASDADIQSKRMSASVSSAHTTPALHLLQWPIIRDLVSKQCDPQVLLQLEMARPPLQLQPPYQLDLDENVHTFARAFFEKVNVWYACVSPYSWHSYYRAASAVGFRSGAETCVVLLVLALGQAANTGRSISRLADGEAIPGLDYFSAAWTVLPGLMIRNDVLSAQCHISAAAYLLYLVRPLEAWNMLCNASMKLQLLLSAPSTIAPQVKELSERIYWNALMIESDLLAELDLPHSGIVQFEESMRLPRSFPYDATVAGSDELPGNDELWYFLAEIALRRLLNRVSNVLYSHKRNSIASLEPVVAELDHQLSQWYEGLPPSIRFPRERLPARDQVQTVLRLRYFACRTIIFRPYIQAVLQDESLAHEAGVQAACEKCLDACVRQLENVMAHHTGHLPYLWQGALSITSQTLLLMGTTLSPVLSSLLPPKQQIDAVISDVVAETERLAHLAPSIRLCADIIREAEERRQVLMQRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTV2</accession>
    <name>A0A9Q8UTV2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766533.1">
        <property type="nucleotide sequence ID" value="XM_047908207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTV2"/>
    <dbReference type="GeneID" id="71988937"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09059"/>
    <dbReference type="OrthoDB" id="3635859at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="37906" checksum="273D1D95393E6FC4" modified="2023-09-13" version="1">MASVSKVFDTEELKVMIFEYFPMSSLLLNQRVCKGWQHTISSTITLQRKLYFEPMQGDPLALFHWGMVSQTHEITPNVYHKIDYSYKRDEYHLPASEQEAEHFDFMWAPETGPRVPVEVVENPILYDFEAMLDDSIKQSDKNKPSLPEAFARPEASWRRMLVCQPSIKTSMRVRIYDRGGSGFDVYCGKHAHSKDYRLGDISDRLSRRKYLKRLRFIARGLMGARQYQALSVEFVGSELWEENQAWTWPEVTEAGGADVDESEDDNEGDIDTLDQDEDDECGEGFEDNANDGNDGNEGEEEDNDQDGMTNDNNPSEEDDDEDDEIEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV61</accession>
    <name>A0A9Q8UV61_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912045.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71992775"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12897"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="547" mass="60564" checksum="601E8FA704DE5864" modified="2023-09-13" version="1">MSGDMAANSYNQAHSDMDQMQNSETSNRESARDKAARDLFTSMVRPCHTSNADNAVNGIPAPPSLPPAVQQQETPVEFTRCTTRLHDNTSPEGDIGLYIMRKYPARWQREHLDDTEEGAGIYQYRLAPQEPPQRVVHPVENTDGVMCDTYLTDVYTVGGNMLCLFVDYNEHEVCIAHWADSREVIEGLLEIELGTREFMKEEKPADVDRDEQMRRNQELRRMQQSWGMRQPQPTRQSQAMRQPMQQPQAIRQTMQQPQATGQPRAMWQPATRQHAMQQLQAMQQLSAQLMQQPRARQQQNTVFPPTNPFAPRSPSAAPSPNDPGAQTGVFPDLRRDSGTAVDGYNMAPQPQHPLPVAYPAWHDQVIPSNGQAQRHQAIDEAALASSHGFNMPPQPQRATSVVNPVQHNEADQPHGQTGLDQAMIDTALETQPAEPLSDEFGLNDAFAMIDNVAAFKASQNSAANDAEASGGLSIPEASLDPMGVEIPQGAGASDKADDAADVQWDERWGFAGSRGILVLTSRDQGEEAMHDAPCFECASWVEGARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV72</accession>
    <name>A0A9Q8UV72_PASFU</name>
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            <fullName evidence="5">Taurine hydroxylase-like protein SAT17</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="5 6">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71993038"/>
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    <dbReference type="OMA" id="CATAYMG"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
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    </dbReference>
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        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
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        <property type="entry name" value="TauD-like_sf"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO23694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="412" mass="46308" checksum="7C03B3E21F709319" modified="2023-09-13" version="1">MSPALTASSSEAPHLLSGKHIDRKIFPDGIKTSGQHNPIYELIRTYSEFPKEISGPTVWKAEDYRNNPERWTHGFSDEEIAELGAAADAFIARGTPLTGMAKELFPLPKLEGFFGAVRNEIVNGKGFILFKNIPVQEWGLHKSAVAYMGLGTYFGYFVSQNGRGHVLGHVKDLGEDPTQKDKVRIYRTNAKQYFHTDGADLVGLLCMAKALEGGESDIVSTHHVFNTLQREHADVIETLVTPNWYFDRKGEQSEGEEPWYKSAIIFLENDPQGSPRVWAKFDPNNVTSLARYNSGLDAKIPPLSDKQKYALQAFEETCTRLALHMILDPGDIQLLSNTHVFHARTAYKDYPPGSVDEQGRPRVRRHLMRLWLSVPESEDQGGWKLPFHDSKEKKRGGIQVNDNAPYCPIDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVL2</accession>
    <name>A0A9Q8UVL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
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    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15030" checksum="4E240BF7CA13D5B6" modified="2023-09-13" version="1">MATYQPCSFPRPPSKEESSIFTKVKYQLHLAYYRYEVNTGQYVMSPGEKLTYNLVVFSLLGLFFFAVSYCLPRSAIAAIHRLVYDLTGHRQALINILRAMDGVVQQSSGGVIARLKGAGVVVALNSNDTDVFAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVU7</accession>
    <name>A0A9Q8UVU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UVU7"/>
    <dbReference type="GeneID" id="71993906"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14028"/>
    <dbReference type="OrthoDB" id="3643586at2759"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="544" mass="59295" checksum="5B08E2B5BA310F42" modified="2023-09-13" version="1">MSSAVCSKAAVGFMQRRQSRGMTLRQTMVLADKRWAVPELYWQLVTGSFRRYGSSFLMLAISLIFLGGVITPLQSVFLTSKTIKTPTHPGQVYRLTDLTDLTPLGFGDSNLVPVLARSAITSAYNTDPQSRLWTGECVSCKSAVNRNATSFGSQYGNEYDSDRPEACEAGGITLGNMSSLPDPFFAQLPSAYNTGLIEQFLPRINSTVTNERISEDEFPSNCDTLPGAFYMSYGDRTDLYHWSIVACMPADQTFSPWKPVRDRQDFPETLYLNISVDYLQVAYQATGFFQITMNTSAGFFELPNYMNGGIPGPLLDHDPGPLCGPACVAQGDIVPAEEPDSRLDSRDIAKRQVPANGTIITSNSSLALEDVENRGPLLTIAIALFGEGSFISDRVKKPDSCIRDVAFDAPNYGTCIGQVPLQGLMRTTYNKDLENTGLGVCVHNGLRGMASLQEQLAPYIHAFYYDEDDGAKAGRISNAFNAAAFLANEAWMTSPTVDATLDVYYDEGADTLVPVISTAGIVTISLLLAADLIFSEDIDGFRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY4</accession>
    <name>A0A9Q8UVY4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768827.1">
        <property type="nucleotide sequence ID" value="XM_047913090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY4"/>
    <dbReference type="GeneID" id="71993820"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13942"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051065">
        <property type="entry name" value="Ras-related_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45704">
        <property type="entry name" value="RAS-LIKE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="35793" checksum="B3B1D2BC7233B498" modified="2023-09-13" version="1">MSLDVTQERLEPNTQSIAPGRNELSACHRFCSTPELIFLCFELAPLQTVVNYQRVCKSWYSIVSSSDILQHRLNHNEYGLALNGRQQLVLQHQIDTLILRCREDPCIGYLVNDHSDDDVPDRHWQIRHTALGRQIGSYWIDECSQASRQRRVRYELPPVCFANFHPPDAAILVYSVSDYESFEEIRQFYYTYYGYVKDSNKRMNRTMPFLIVVANKTDLPEHEWQVPAEVGRHFNDSIDAPFLQVSTKTGEGIPQDASDVVVKRILYEHWMTRVRLTLHGWSRNRARSSWAGAVLQSLISFFQVRLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW44</accession>
    <name>A0A9Q8UW44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Agnestins efflux protein AgnL12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13639</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769020.1">
        <property type="nucleotide sequence ID" value="XM_047912787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW44"/>
    <dbReference type="GeneID" id="71993517"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13639"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF250">
        <property type="entry name" value="MFS-TYPE TRANSPORTER AFUA_1G00970"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="11"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="45219" checksum="7ED9C50FB0A8E29D" modified="2023-09-13" version="1">MDRLIKLSLRSMLALAASALAYFTTIGFVNAYGVFQQYYTAHYLPDYSNFQIAWLGSFATFTLFACAAPAGTLADRYGPTIPICIGVILQLLSIFMVSLCREYYQFFLAQGVLLGISMALINIPTSTIVPKYFKRHRGLAQGISIGGSSLGGVIWPIALDRMLNYDDIGFGWSMRIVGLAMMPMLAIAILFLRKPVDLKSHEPTSGSEKGTATIASSAKQSRKKRDLTSLKKPPYILLCLGLAIANFGYFVPLFYISTYAVSLGFSENLAFYLISILNGASLFGRILPGLVADRYGHFNIMTIAVFLTGLIVFCWTTATSVAGLVIRAMAFGFISGAILSQMVAYATVLSTGESYGAGIGIGISMGSVSFTALFGTPIAGELVKYGYIALSCFSGSALMVGGVFIACSRLAQDRRILAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWC5</accession>
    <name>A0A9Q8UWC5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit SPC19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Outer kinetochore protein SPC19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_14438</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769275.1">
        <property type="nucleotide sequence ID" value="XM_047913586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWC5"/>
    <dbReference type="GeneID" id="71994316"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14438"/>
    <dbReference type="OMA" id="DCCEEAH"/>
    <dbReference type="OrthoDB" id="3361333at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013251">
        <property type="entry name" value="DASH_Spc19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08287">
        <property type="entry name" value="DASH_Spc19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO24909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="170" mass="19261" checksum="9194951763DD3A57" modified="2023-09-13" version="1">MDTSTQNALQGCVSSLQSSMQLLESSINILDSGVNDYPRLGKVLQTTRHFELVSEHDLITAQSSLLSEIQPEVSNLLSRVETYLDKLERREKSLIAKAELQEGRLQQPSRASQGAKSPRMKGGASGLDKLEELKYQQLKQKKERLSYAVERLELQANQRQRQLRKSMAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWN7</accession>
    <name>A0A9Q8UWN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769458.1">
        <property type="nucleotide sequence ID" value="XM_047913286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWN7"/>
    <dbReference type="GeneID" id="71994016"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14138"/>
    <dbReference type="OrthoDB" id="2269179at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="186" mass="21212" checksum="F0128869AC925877" modified="2023-09-13" version="1">MDFLHFLLPHDMALASSWNTLLNFPIFVRPVKLAGMFHLKESTSTTLHPQRGDHLFYIRTFALTAAQLVQAKAKLEEAGRNYPKLDTWCQMLEYLADYDTEIYVRYVGTTSTVFAWQRFSTDLEQLTGGFHHNIMEALSKIDPQIVAGCRVHTFSEADRPALKGENGVIHRLDFTAPGMRYCALVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWQ2</accession>
    <name>A0A9Q8UWQ2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase AgnR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769650.1">
        <property type="nucleotide sequence ID" value="XM_047913269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWQ2"/>
    <dbReference type="GeneID" id="71993999"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14121"/>
    <dbReference type="OrthoDB" id="432536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053275">
        <property type="entry name" value="Agnestin_monoxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38688:SF1">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38688">
        <property type="entry name" value="PYR_REDOX_2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="24"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="48740" checksum="0F322EDF3B365621" modified="2023-09-13" version="1">MSKPTQPSSTRRATTMSGPFGTYEAVVVGAGPAGITAVGNLLENRVERILWVDDSFDGGRVNKYYREVPSNTKVKLFIDYATAVAPFRKIVSGLPSRDRWEEPSASDGVPVDGRQDKLQDLRHLDQEKGCTLSYAADMCLMLTQGLKRTPGIITQRGRVSDASLDESTSTWTVNIDSENKTAQDITNLQTKRLVLCTGASPKDPPLPFEPAGMKHLHLDTALMPSQLSQILSSSTPTTIAVIGASHSAVLVLRNLTNLALSSHPNMHVKWFTRHPLRYAEYEDGFIARDNTGLKGEAAVWARENLEPETLPSSSISKVLTKVAYQSGTEKEIYKSQLPGCEYVVQAIGYNRDPVPAIKLSSNGSVITPHFDHDIGVFNYVRESSDGAVGKLERLPGVYGAGIAFPERVVDKKYGHEEFNVGFFKFMKAVKKWVGEWKPVAEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5J6</accession>
    <name>A0A9Q8L5J6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="20">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CLAFUR5_01950</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 20">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a beta-D-glucosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine(out) + ATP + H2O = a beta-D-glucosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66036"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:22801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:66037"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Membrane</location>
            <topology evidence="20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="20"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755637.1">
        <property type="nucleotide sequence ID" value="XM_047901098.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71981828"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01950"/>
    <dbReference type="OMA" id="QALRCGR"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990531">
        <property type="term" value="C:phospholipid-translocating ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015247">
        <property type="term" value="F:aminophospholipid flippase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140333">
        <property type="term" value="F:glycerophospholipid flippase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140351">
        <property type="term" value="F:glycosylceramide flippase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000048">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000108">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
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        <property type="entry name" value="HAD-like_sf"/>
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        <property type="entry name" value="HAD_sf"/>
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        <property type="entry name" value="P-type_ATPase_IV"/>
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        <property type="entry name" value="P-type_ATPase_N"/>
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        <property type="entry name" value="P_typ_ATPase"/>
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        <property type="entry name" value="P_typ_ATPase_c"/>
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        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
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        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
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    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
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        <property type="entry name" value="Cation_ATPase"/>
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        <property type="entry name" value="PhoLip_ATPase_C"/>
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    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
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        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
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        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
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        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
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        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 19 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 20" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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            <end position="162"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
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    <feature type="transmembrane region" description="Helical" evidence="20">
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            <begin position="1223"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1264"/>
            <end position="1282"/>
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        <location>
            <begin position="1289"/>
            <end position="1306"/>
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        <location>
            <begin position="1326"/>
            <end position="1347"/>
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            <begin position="107"/>
            <end position="163"/>
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        <location>
            <begin position="1109"/>
            <end position="1358"/>
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            <begin position="1"/>
            <end position="26"/>
        </location>
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        <location>
            <begin position="1384"/>
            <end position="1574"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
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            <begin position="259"/>
            <end position="270"/>
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            <begin position="1436"/>
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        <location>
            <begin position="1545"/>
            <end position="1554"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5L0</accession>
    <name>A0A9Q8L5L0_PASFU</name>
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        <submittedName>
            <fullName evidence="7">RNA exonuclease 3</fullName>
        </submittedName>
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    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the REXO1/REXO3 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047900717.1"/>
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        <property type="component" value="Chromosome 1"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF112">
        <property type="entry name" value="RNA EXONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="6">
        <location>
            <begin position="435"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="631"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="685" mass="75327" checksum="F811D982297CA394" modified="2023-09-13" version="1">MVFSTTNLFKGIACPKGEKCDMTCCIYAHDERVDVAASQPTLSAAPTHKAIDRLTQSAHDFREPAAKRRKITYDRLQDKPPSRADLIRKQLAAVKSKPPETSSREDARGSKTGAVQAQPPSSLAPPVSPPPKRSTSQHDSTSAANSEPGKVIVKGPDSEKVETLNPRLIANDPVGHSKRSAFLKRLHQEMAKLNSRVAAAANVDFKAVLHLSEQQLIKLALGEEEKVVSHQPQVYTNVIKQRIASLMKMSVEDWIKDLKPRIVIPDSKPSIKGEKLIDTGLPLEQEHLILPQLVADQKPLAAFGYVPEPPTIEQAAEAAAAVEASQNWEICDRCTARFQIFPDRDEKGRLSSNGPCRHHPNRKVFPPRSKTDKETGDKQPYFPCCTAAVGEVGCTESPEHVFKTSSPARLAATMPFIKTPENEAPSRDRRDKKVNAVTFDCEMGHTTMGLELIRLTAVTWPAGEPLLDILVRPLGAVMDLNSRFSGVFPEHFADAIPYDQWLSSPPPPPRDDGASPALPIVDSPQRARELLCGFITPTTPLIGHAIDNDLNTVRLCHPTIIDTVILYPHPRGLPMRFGLKMLSQRYLQRAIQTGGLRGHDSLEDAVATGDLVRVKVREKWKQLRSSGWSIVNDQLLPPPPRKPSVEEAGMASAEQHAKDMVGKALHGTKRKKRPSTDSSEAEDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5X1</accession>
    <name>A0A9Q8L5X1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">6-phosphogluconolactonase</fullName>
            <shortName evidence="6">6PGL</shortName>
            <ecNumber evidence="4 6">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="4 6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755159.1">
        <property type="nucleotide sequence ID" value="XM_047900735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5X1"/>
    <dbReference type="GeneID" id="71981465"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01587"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="OrthoDB" id="432544at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000005">
        <property type="entry name" value="6-phosphogluconolactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="7">
        <location>
            <begin position="15"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="29260" checksum="5B883F1D1B212656" modified="2023-09-13" version="1">MGRPANLYSFKDIDKDLAPNLRKYVLDAQKEALDRHNVFCIAVSGGSLPKTLAKALLAPSNGSKEDTPEFSKWEIFYADERCVPLDHDDSNHKLVKDDLLDQIPQEFGQPKVYPIDTTNLEDPHEVAEQYQQQLMDIFAARDSVRLPLFDLILLGCGPDGHTCSLFPDHPLLRETEGWVLSISDSPKPPPKRITLSLPVVVHGAKIGFVATGGGKKDILKKIFETEEGRNLPSGLINEGAGEKVSWFCDAAATEGVNFPRRGSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L653</accession>
    <name>A0A9Q8L653_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_01356</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755923.1">
        <property type="nucleotide sequence ID" value="XM_047900504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L653"/>
    <dbReference type="GeneID" id="71981234"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01356"/>
    <dbReference type="OMA" id="VIRWTGY"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF3">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="331"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="518"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO11557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="633" mass="70955" checksum="0B7E80EBAAE45872" modified="2023-09-13" version="1">MDSIVARHIQDHGEANTTAVKYWGYAERILPCRKDAGTCEYLEAVYTMHDTSMLYSFILWGVILGILALWTALRIRSIGVASQGRGGLVDDMCSQVGSWQKFLLPDAPMRWLFGRVSRLQIVVLAVILAYLLIFSLIGIVYKTWVTPIKDSSLSNTRTGLGGWADRVGVLAYALTPLAVLLCMRESILSILTGIPYQYFNFLHRWLGRVIFIQSALHTIGWTIVEAKLYQPQPSVYVTFIQQQYMVFGCVAMLFISFLTVFSFKPVIRWTGYEFFKVTHWIVAVLYIGACWGHWDKLYCWMVPSLALIVIDQCVRYGRMAYLHSTGGKGRSSGFKCDQARMQVLTDDNGTVIRLDFEHEHATSWKAGQHFYLTFPSLSIWQAHPYTVSSVPDPNASTQTHTYLIRVRNGQSKQMVALGDCAIPVIIAGPYGHGFPSYESRHVLAVAGGTGVTFTYPIIMEFIRQSMSRRAVQDFVWVVRKSEDLLWLGTELREMKGLLKDMLGLTITIFVSRESRVGKGGEESESSLRHESDQERSVISEKGKETAAVDTTAVEVSLSDLLAPAGSRFKVHFLQDHHPSVAEVVTDFRERSANIGGPVEIVGSGPEAMGTDIRFAVSKIDEGDGVSLYWDSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L699</accession>
    <name>A0A9Q8L699_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00396</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755943.1">
        <property type="nucleotide sequence ID" value="XM_047899544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L699"/>
    <dbReference type="GeneID" id="71980274"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00396"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000053">
        <property type="entry name" value="SNF2 family helicase/ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF14">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="323"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="866"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="720"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1058"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="720"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="776"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="823"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1058"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1089"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1100" mass="122286" checksum="5BC3B2E8499A3E79" modified="2023-09-13" version="1">MVRETNPSRTSSGHYLSPQKRDVQERIPLANISAKMQSPSPKAPAVDGDGKAANISLSDITFGEASPLRNPLRGPTQPRKQTSSIFMPKQRPQQSIRPTTTSRVTSDEYPADQRDFYFPGQRQASSSWQAAHDANAQRNHGPSATNIYRPTNAPLQTFHPPKPTFSSTAQADFYKSALNPPKSVVDLTAQDDDSDGERFDPDAAIRAESRNFGSEDPYMYVDANKASENIKNLLEGAFDDEESKGKTRLRRRAKTRDAEEAESKGLASKLAALNVKDDTPTKDDDEDAEEEEDGTVDGLAVKLLPHQVEGVSWMIDKEIGQKKVKGVLPYGGILADDMGLGKTVQSVALLLTNPRPALDAKPERKNQKMPGREVGKGTLVVAPLALIKQWESEIKTKVSKSHALKVLVHHGASRTKSGDQLRKYDVVITTFQTLTSEHAGSNMLVSGGTRIGCFGVHWYRVMLDEAHSIKNRNAKATQACYALNSWYRWCLTGTPMQNNLDELQSLIKFLCIKPYCEQPSWKQDIIQPMKNGRGGLAMRRLQYFLRAFMKRRTKDILKQEGALNFGGKTGKDGENKGGMQIVKREVLTVECELDEEEQDFYSRLQARADKRLDEMAHAAKADYIGALVLLLRLRQACNHPRLVEMSMSKDKDAMTTGMAGAQTPRKPSGNDMDDLAALMGGISVQTKHCDVCQVKLSPVEARDGAVRCSECEDDLAAVKKKQKEKKHKTKATKSKAQAVKAEVKLEQRRARNRRIIDDSDDDEDESHAEQGKAGTTDDEDEEGGGETLDTIDSDRSDEDDSDVVDSPSRAKRISGRGGKEGDEVSDVDDQSEEDDEDGESDDSDSEANILDGVGTSGKSSHTPSTKIRHLLRILHKESPKHKTIVFSQFTTMLDLIEPPLKTSGLRFVRYDGSMRPDAREQSLNSLRTDPKTRVLLCSLKCGSLGLNLTAASRVVIVEPFWNPFVEEQAIDRVHRLNQTVDVKVFRLTVRNSVEERIIELQEKKRELAKAAIEGGKGVGKLSMKDILGLFKRDAEHGGHDEEDRELWQKFGGDNRLLDHRNEISTDDRGTTMGTGSRPVSNRPQAKARPHQEHDVYGRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6C1</accession>
    <name>A0A9Q8L6C1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01236</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755995.1">
        <property type="nucleotide sequence ID" value="XM_047900384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6C1"/>
    <dbReference type="GeneID" id="71981114"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01236"/>
    <dbReference type="OMA" id="RAYNSNH"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000008">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="9">
        <location>
            <begin position="100"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="10">
        <location>
            <begin position="280"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="37710" checksum="4677190D8EC98C8A" modified="2023-09-13" version="1">MASEDDQTQTGYEDGLAGGPGAPTPLSGLEGISGLTKRDIQLFVDAGYNTVESVAYTPKKVLETIKGVSEQKATKILTEASKLVPMGFTTATEMHQRRSELISITTGSKQLDTLLAGGIETGSITELFGEFRTGKSQICHTLAVTCQLPFDMGGGEGKCLYIDTEGTFRPVRLLSVADRFGLSGEEVLDNVAYARAYNSDHQLQLLNQAAQMMTETRFSLLIVDSATSLYRTDFMGRGELSNRQTHLAKFMRILQRLADEFGIAVVITNQVVAQVDGGPSAMFNPDPKKPIGGNIIAHASTTRLSLKKGRGETRVCKIYDSPCLPESDCLFAITEAGINDPAPKDLEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6J9</accession>
    <name>A0A9Q8L6J9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756176.1">
        <property type="nucleotide sequence ID" value="XM_047899363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6J9"/>
    <dbReference type="GeneID" id="71980093"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00215"/>
    <dbReference type="OMA" id="RLQSGTW"/>
    <dbReference type="OrthoDB" id="4158987at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="25868" checksum="D42497906CC530AD" modified="2023-09-13" version="1">MPPKEAGPPSRAELLQAVAASQKVAQAQEYATSLREKAATLSNPSERERLVEEAYAREVEAHGERSKIARRLQSGTWQGGAAGGGIGLGTGLGLGTLVGTLLSGVLSIPTAGLGILIGAGVGAIHGPWIKVGGKDKKWQDATPEEVVAYYEEQNAQNQSTAEQALTYEQPIGPVMKKKPRKLEVRSQANAAVGAPVDAEDTISTGTPRRPKKLQLRSQSQVDSLAAMQREMGKENVDAVQEPKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6U2</accession>
    <name>A0A9Q8L6U2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tat-binding 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02142</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756212.1">
        <property type="nucleotide sequence ID" value="XM_047901290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71982020"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02142"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140674">
        <property type="term" value="F:ATP-dependent histone chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05491">
        <property type="entry name" value="Bromo_TBP7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001218">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000016">
        <property type="entry name" value="ATPase family AAA domain-containing protein 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="677"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="158"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1343"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1343"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1369"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1395"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1460"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1481"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1508"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1535"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1552"/>
            <end position="1575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1701" mass="188014" checksum="1C774B5800B103BA" modified="2023-09-13" version="1">MAKRERPFDPNRSDSDDLDFNDEPSSPRARPHKRARKSHKGSPTKRPAKRRREAYNDSDIDPDSNEPSEEEDSFAESDEDSEPVETNPRTGRGVRSAAKKRKNYEESDEEAGELLNSESEVDRHTPARPKGKRSARAERLQKRTLVVKLKVPPFTMVKDKVVPRSTRASSRQLKREPTPQATRSAPGMTRRSSRLSHDEEQPLVALTDSGKHELVTRTGTVTPEPEGSRRPSRGGKGLASKKPPSAIFEVSQEDSVANDPVGTIEQTEEGEKFFSQLQDAAGGQDAQQVSRTSPATSAVKEDDIRMEYEEEDEEEQVVQESQHDPDDNDDDDEPVSKGGRSLRPRRKASTPPTSQPANNNARRSLRNRKSGGIEQSSDFEPDAEGEADVEEEGMSDSDELLKPPRGRSSAEASSQGGRRSGRLRGKTTSNGSRSRRSPEEDELDPEEIADEAAELDEDNRRIRRERPRKQRSQRQEISFEPTSLRNRANRPDYRILRPELLLPIEDDDAPAVATTTPQRNRRGGGGGGRAGAQYRSLFSTFGPFGGAGGPPPILGGPDGAGATGGVDSDSSDDEAAMRGQQSGVGGTVGMTPTSAFPKPFVAQAHNSDPIQGPGGGPPGLGKVKDKKALADADPLGVDTNVTFDGVGGLDGHINQLKEMVMLPLLYPEAFQQFKITPPRGVLFHGPPGTGKTLLARALASSVSTHGQKVTFYMRKGADALSKWVGEAEKQLRLLFEEARKNQPSIIFFDEIDGLAPVRSSKQEQIHASIVATLLALMDGMDGRGQVIVIGATNRPDSVDPALRRPGRFDREFYFPLPDVMGRRKILDIHTKGWEPPLKDEFKDQLAEVTRGYGGADLRALCTEAALNAIQGTFPQIYSSDEKLIIDVTKIKVLAKDFMISVNKIVPSSERSAASGAVPLKKDIEPLLRQPLKEIGEYIEQTVPRKRKATALEEAMYDDRDDELGFEKETMHRNFESSRVFRPRLLIKGHVGMGQQYLGAALLTKFEGLHVQNFDMATLMKDSSRSPEAAVVQLFEEVKRHKPSVIYIPNVNIWWDTLADSVKRTFVGLLRSLPPNDPVLLLGMMELYQDDEPDPHMLRDLFGFASKNQYKLDRPCEEARGEFWRAILDFVKKTPSEFPEPENRKKRKLAELPVAPVPAAPTGPTKADLKAQKKKDHQTLNMLKLLIQPVMDQIKLKYRKFRNHIIDENTIGYLYDEQDPMVLSTDLTEEQKQQQLLFRPFEKDTDDKGNEGLREQSTGKFYYNLEIVTIETRLSNGYYKRPKDFLGDIKKLAKDAKTSGDQERTLKANEMLANVEVDMTTLESQHPALIAECEAVYHREQERIQKAEQKRAEAQGRGETVPKIIANVPPQGTSNTTTETSGPVMLGQAVPGRQLFPTTPNKPQYPPSVQWSTTQTNGSHPSQHTNGSTVPSKPQEDSEMLDSHVETQEHQPAQTAPPQRGQAQSPDQSQSQPQGAYYHKIGQSQPAAGVQTEQNSASTASGNKTSDRSSGGSVNTTNSNGAIMHPDFSIYGAAGGSSQLPDTQPPSLASQPGAGSQHNSNSSGGSQPSASSQQMGPPQPRPATRPPSFANISNILNKDDDDEEEGTTHDDIDESILRASQKYILDAESLERFHGELVEKSSGLSLEQLEQVNAALMDVIWRQRGEWNRDLVWHEVQQCFNDTIRDIEELQEIMDPKSLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L728</accession>
    <name>A0A9Q8L728_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NAD-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00754</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756418.1">
        <property type="nucleotide sequence ID" value="XM_047899902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L728"/>
    <dbReference type="GeneID" id="71980632"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00754"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="94"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="24383" checksum="5E0E05CE5AB51E8E" modified="2023-09-13" version="1">MEVGDPVILHPLATCGLCRACRFGDDVHCENSTFPGINVDGGYAEYMKTTARSIVKLDPKLKPADVVALADAGLTAHHVASKAAKFLRPGDNCLAKQIGADHTVQATDDGSFVKEVLELTNGQGAEAVIDFVAEGGSTSTGVKMLRRAGNHYVVGYGENINIPTIDIISAEINFIGNLVGSYNDLVELMTLAAQGKVKLHTTQYKLEDFQKAIDDLSSGKVRGRAILIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7N7</accession>
    <name>A0A9Q8L7N7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756791.1">
        <property type="nucleotide sequence ID" value="XM_047899322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7N7"/>
    <dbReference type="GeneID" id="71980052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00174"/>
    <dbReference type="OrthoDB" id="2131701at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="85"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="23334" checksum="55207BC47A53E060" modified="2023-09-13" version="1">MLLDLVLTPHSNTEVDFLHSTSLSLTTMAPVEDNKWYTIHLYNEFHDDGAGDEVVDLDSGSSNNGTHCKVWTYKDDGGSGRYNMSWRAVIADKNMDDGTIYWSFQNRAGTTYMDLNHGSNGVGTQVQGWGTNGSNAQQWSLVETKGNDRQTVCWRLKNRASGTVCGYWGVPVHGVDIRGFFPSSDTPPAPGRGARDTSQLFVFKERNVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Q4</accession>
    <name>A0A9Q8L7Q4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Stergiopoulos I."/>
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    </evidence>
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                <person name="Samaras A."/>
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        <property type="entry name" value="HELICASE_CTER"/>
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    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="445"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="924"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="812"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1068"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1102" mass="123417" checksum="0652CCAEAEED4AF6" modified="2023-09-13" version="1">MNPAQLLNPKAFAKGKAMANRRTQNNAASTPNNAPPQPMTYDPKTLLNPKVAGSSDGGSRGATQPDSNASTTAKDESDDINFGISSMIENLHNTHERDDAPARKRKAQVIEGITDDQRKKAKGQSVHSGSGGMLSSHLKEERKQFANDAGDTIDLTNDDDLQPPQSNDDEVQFIKDSGDDEVCLGILHVSCNVYMIPYTSAGGAAKAVGKDHWPAMGIQFVRKPASNTVMELIDRTAAKFAHLDPRVASALCPLADGSKINNIRMKMFLPARPKRQGDYCGKRVSQNIKVDVTLFGRRRMSDRIGQFLSQKQLYLSSPVTNVGKPIVNPHDKKPVSFSKQPGTILGPRPQPSIQAVGRTIEEMRREASSMFDGLAKAEDLPEMEVDGTIIKSPLMAHQKQALHFMMDRERDGYTDDSPSHSLWKYRSKDNGRPSWYHIITDTEVFEQPEPIQGGILADVMGLGKTLSILALIAETREAARRFRREDPPDSEYLECNSKGTLIICPKSVLSNWQEQMRQHTVDGKMRHYTYHGDSRMQDTEQLAKYDIVLTTYNTAASEFSNSGGASTKYTALRSMKWFRIVLDEAHSIRNSATKIFKGCCELEAERRWAVTGTPVQNTLNDLGALIKFLRLKPFDNLTTWHQYIMAPFKNGDVEVINKLQLLSGSITLRRLKNTVGLPERAQVRERFEFSKAEALLYRKFAAKTRTQFHTLSGGGNKLQGKSYAHILKSLGRLRAICAHGREMLTEDDMKDIDGDDPDNAIVLDIGDEPDFESETDFVTEKQAYEYFKMLHDGTMAVCQSCADHLLPLDGQAQDELDDSSDDDADSNVGSADTFDGKPNLFGHLTACYHFICTKCTSKHQKEVQENMSVDQHHVCPHCTNYVQYGFFPLRRSILARFSDERKDAPGRAGIAKWDENTYSGPHTKVKALLEDLRQSEIETSQLPKGEPPVRSVVFSGWTQYLDLIEFALVQNNIGFVRIDGKMSVKQRSESLTIFNTVEHVRVMLVSIKAGGQGLNFTAANKAYVMEPQFNPGVEHQAVDRIHRIGQKRDVVIKHYIMKGSVEEGILTMQKKKEDLAKLSMERKRSKAEEVKMRMEELKDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9T0</accession>
    <name>A0A9Q8L9T0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757869.1">
        <property type="nucleotide sequence ID" value="XM_047902264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9T0"/>
    <dbReference type="GeneID" id="71982994"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03116"/>
    <dbReference type="OMA" id="QNMSGDP"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000011">
        <property type="entry name" value="Spindle pole body component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="165"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="504"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="882" mass="98884" checksum="A347A89B04399032" modified="2023-09-13" version="1">MASHPPSRAATIADRRASASVRQPKSRPTASNVASPTTEDGRTDSRSTHHHSVKTQSTETTTRDTLTRDTLIRRTLSPTKTQFDGSNGRKSFDIERPSSKDKSVRREPEEAAAQPWSPHATLLAPSSAPLASRISAAPVAAKAPASIQPQPLGSLSLDAQERAIIEDLLFVLMGCEAQYIRYANAYDPLDEKSQLAGPTFNVQPGLDPSLRDLAHSIVKTAKHYCAVEAFVEVQSREEMGMVNHALCAAMRKMLKDYMILVAQLEHQMLTNERFTLHQLSLHTRPTAHMMLQLYSVAHEILKENSMLDNEDDIDQTDDFENILESLKEGKDTGIPGKKVCKGGSVLKLLAKRSAAMAGDPAARQLLNLLLREASRPYMAMLNEWLHHGNVRDPHQEFLIKEQKSIRREGLEQDYTDEYWEKRYTIRQELVPPQLESLKDKALLAGKYLNVVRECGGIENLSRDLTSSAEFPHTFDDPRFIENVSGAYAFANRSLMTLLLTTHELPSRLRSLKHYFFLDRSDFFSYFLELTNSELRKTAKNVNVGKLQSLLDIVLRQPGSVAAEDPFKEDIKVVMNDVGLTGWLMRVVNVQGMDADATSLSSYNPAATSVEKDGKEISGYEALTLDYAVPFPLSLVVSRVTLTRYQLLFRYLLSLRHLETLLTNSWTEHTKVRAWHHKTKGDPAVAKRIENWKRRAWCLRSRMLCFVQQLLYFCTSEVIEPNWLAFMSRLSHAGEEDKSDTEPRIKRTVDELMQDHVDFLATCLKECMLTNSKLLRINSKVMSTCTLFANYTASLSRYLASADPDLASPSSASQTAYDPAKLDKLFSILQQYEDHFSRHLKILLDALNYLAATETVVFLGLCARLSMANEGGPGGGPGPGAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Y7</accession>
    <name>A0A9Q8L9Y7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Patulin cluster transcription factor patL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03098</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757918.1">
        <property type="nucleotide sequence ID" value="XM_047902246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Y7"/>
    <dbReference type="GeneID" id="71982976"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03098"/>
    <dbReference type="OMA" id="YEHFWQM"/>
    <dbReference type="OrthoDB" id="2406834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF81">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="672" mass="74587" checksum="CF3719180F38FDFF" modified="2023-09-13" version="1">MQRQHDAPQEASADAGPDTHSTTNGAAHARTTTLARLASPPQAASASASASASASASPEARGHRVKPKQKRNKPTLSCLECVERKTKCDRGRPCLACVKRQSSCGYTAVANLIASADRKHGAPTNKARYVTKPSSKVRKTASITSPSASLTSPSVGTDNGWPSIGGRAPRASLSSFQRVSPLQVSGVPISQSSPSNVFGVGSQHPFANYWTCQGGLPEVITVLPSKEQADILVAKYFEAVDPVYPFIHRRTFYSDYESFWALSQDEKGRTDDASLIALHYAMYALGTQFMQFPAYEERSQTAEFYCSAANQALRVYSYLNRTSMRAIQAMLLMAYFLMNDNHASDAYAWAGIHLRQTYALRLHRDPDIIVPDASVLEKQQRRKLWQAVFFQDTFLTVLLKLPPTATHSDVPVEALADENELSNDGVEVCIGAHRVENLMSINVIAPQMSQPLAPPQPHHLVDQATVKNDIAYMRSMWHLGNLVQENLSSPLSLSLPIANSPRHKDSLVAAFKRLYKSFPAPLTILDYGILQQQVTPHPRQIRQNLFLTSNYFHCLMLLHASDNPEASVEANPKAALEAAHEALCAFFKLWGLFETEAGVWWAFQHRAFEESLLVANLLAHSPMPERHIDPIYGKAKEDIRRMLEIMQRYGENVETHKTRMEVLHEAFQRIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBI8</accession>
    <name>A0A9Q8LBI8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Aminopeptidase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_03278</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758725.1">
        <property type="nucleotide sequence ID" value="XM_047902426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBI8"/>
    <dbReference type="GeneID" id="71983156"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03278"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF171">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 14" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="13">
        <location>
            <begin position="150"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="11">
        <location>
            <begin position="389"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="12">
        <location>
            <begin position="679"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO14359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1017" mass="113816" checksum="95DCC971DDF96E41" modified="2023-09-13" version="1">MLRISSSRLQGIAHRTSYIVLHCGPSSTARSPGLRCIRMRSSLGLQRLVAGPTLVRSGGVFAACRHRTTCCLSRPLSLPAQARDQTFTPPNPRRSAHTLVPKARDRRVARRTAYDIPQQYQSIRYCSSEASSLLVKMASDRDVLPEDVKPINYAISLKDLKAGEPWTYQGTVDITIDIRNATKEIVLNTHQLKVHSAEVVTDSGKQSSSVQASSISFDEKSQRCILLFDQALEKSPKALLAISFEGVMNDSMAGFYRSKYQPTVEASKGVARDDKNHYMFSTQFESSDARRAFPCFDEPNLKATFDFEIEIPDDLVALSNMQEKNTRKSKDGHKMVSFDRTPIMSTYLLAWAFGDFEYIEDFTRRKYNGQSLPVRVYTTKGLKSQGKLALESAHQIVDYFSEIFQIDYPLPKVDLLAVHEFSHGAMENWGLITYRTTAVLYDEVSSDQKYKNRVVYVVAHELAHQWFGNLVTMDWWNELWLNEGFATWVGWYAVDHLHPDWNVWGQFVTEGMQQAFSLDGLRTSHPIEVPVSNALEVDQIFDAISYLKGSSVIRMLAAHLGVKTFLQGVADYLKAHTYSNATTSDLFSALSKASGQDVNTFMEPWIRKIGFPVVTVAEEPGQLSFRQSRFLTAGEVEAKEDETVWWIPLGLKTGPQATDAQREPLTTKEDTYRDIDTDFYKVNANQTGFYRTNLPPQRLAALGKGLDKLSVEDKIGLIGDAGALAVAGEGTTPAVLSLLESFENESSYLVWSQVLSSLGKIRSTLASDKQVSEALKAFTLKLISPAVEKIGWEFKSGDDFLTGQLRTLLITQAGLVGHEKVVAEAQRQFKAFTGGDQKAIHPSLRSAVFVTAIRAGGTDTYEALKSEYQTTKSVDGKEITLKAMGSVQEEQLALDYLNWALNGGTAIQDIHNVGMPLGSNSKVRHVVWEFVKSNWPTLREKLGANMVVLERFLRVSLMQITEENIRQDIEKFFADKDNKGYDRGLAVVNDTILGNAKYKERALEGTREWLNAHGYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD86</accession>
    <name>A0A9Q8LD86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759632.1">
        <property type="nucleotide sequence ID" value="XM_047907593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD86"/>
    <dbReference type="GeneID" id="71988323"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08445"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="65" mass="7435" checksum="8DE866519B4EC243" modified="2023-09-13" version="1">MRATKESIAEQAPSKGVFARDRKRFSDLAALPFVASNVQEIVKVSHDQSREWELNISDNIIEELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEM6</accession>
    <name>A0A9Q8LEM6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760382.1">
        <property type="nucleotide sequence ID" value="XM_047903655.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71984385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04507"/>
    <dbReference type="OrthoDB" id="5382203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="917"/>
            <end position="935"/>
        </location>
    </feature>
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        <location>
            <begin position="1008"/>
            <end position="1035"/>
        </location>
    </feature>
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        <location>
            <begin position="1043"/>
            <end position="1055"/>
        </location>
    </feature>
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            <begin position="1108"/>
            <end position="1120"/>
        </location>
    </feature>
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        <location>
            <begin position="1121"/>
            <end position="1134"/>
        </location>
    </feature>
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        <location>
            <begin position="1163"/>
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        </location>
    </feature>
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        <location>
            <begin position="1232"/>
            <end position="1252"/>
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    </feature>
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        <location>
            <begin position="1257"/>
            <end position="1270"/>
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    </feature>
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        <location>
            <begin position="1303"/>
            <end position="1312"/>
        </location>
    </feature>
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        <location>
            <begin position="1355"/>
            <end position="1368"/>
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    </feature>
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        <location>
            <begin position="1371"/>
            <end position="1380"/>
        </location>
    </feature>
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        <location>
            <begin position="1445"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1481"/>
            <end position="1493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1501" mass="162601" checksum="19536E2FAE82DF0E" modified="2023-09-13" version="1">MATSSSASAYHSHHSHSHSHSRAETPVSPLVSDFPLPGHSNHHTPSSSNAYSRFNSNVHDLSPLSGTPPIMSPSPSISSYSNSTWTSQLPLNIATVHPPPAYVAQFGAAQVVSDRKRRFSDDEDDDVRTTISSMRDDVQFSQPALILANAFLDQLLYSFLANARSTTLTALRPAVIEVLKSRLATEAIASAEEELQELLAGGDDEEEEMNHRQTLAERQRKWDTELVWKRTRLRVMVYIRLGEMEDDDEERYVRENELFQGADRRFSQSSGLVSWAAAIFLTSVLEYVAEQTLQVAAQAADSRARRQCRNPRAPTSAFGMVSPVDGVTVEDYDMEKVALNSGLGRLWRTWRKSLRSNANGAPLSPATTSSNNFSRRLSRDIFGPGLNPRSSFGTGPDALSVMEDSRRPSLMTTDKDVTQVAEDGVEELPEAGYPEHVLAANIPLPIGDEVRDVDEIEVPGLARDPDVPEIDHESMAVAALPKRRNSFSSHANFMLMDKPVRDTTATLETPETKLPDVGASKKPILTRKRSASVPMRIPGAFPVFEEPIAEEAVEHSEATEPVSEDAVKADPKPEQKANAVEMAIHKRKASQSPDAKSLEDKVVQEDPVSEVTDAKDTHKGVLGLAAAGSAAAAAAALSAVYGASPNKKTKRQSMPPVETDIEQREQQKKRNNMKRLSVPVAVRTLSWQKVQDQDEPQTARRVSLSSPNTPPTIVQTHSSSTVTSPIQETLDDDRSSEKTSQQASATPRYIASGAGPDQESSKEEPVDIGVARTSDTAVASPKPDDSSEEFRYARDRDSYTNPNPRRPSRLFIGTQPVEAVPTKTDNPPAQAQKTEDLPVTSPEAFLSKRSLAVSPKVKEAAEKAKEQTPTHDLPDGDVKPTTHAITTGKSGSSPQPSPGVEKIPEKSENWVPHSKKSASVSEAAAPPASVQPAVPKMTVVKKKEAPFKEEAVVSLTSASIKGPEDFEMFVQGGDTVKYTLTPENVRDDPSPIDAVPIRKAARNHERSTSAPRKQSPSAETRTGRSQSSKHITSASPLPPDTDDDHRPRKDSDKRRSISRPPVRNVSAHRRSGLMAREPQVLTESTRDFADFIRSTGPSKEQEVMPILNNRSTTSLHSLLNGSRSSSPGAASARSLNRSTFSKDPIPPLPAMPSKGKGNMQARGATTNADGSTSELIDFIRSGPSSNGQGDRQHRISRTVAPFRTTMDSDQADEWGERLVAQPDLKLTNTTQSAPSLKSASSVKSSHKTSANSRAPLLSQTTTNENVQPTHNGVPPRLSSMPKQAEGGAPAPKRYRNKDPYAIDFDDDDEDDDLLKALPKNARVREEESLIDFLRNSEPPASHTPRTASAPAGRRQGSTSGIKNFSSDAVSLDRSGSASSRDGGRPAKQACTYTVGNAPAPPRSGGTTSVAIGGLGKPPPPKMQARGFGKQQDDGGMQDLADSLRSSGPSTPTQPTPIATKLNQTSSRTSVRTDTSKKSRRSSFFGLFSKKSNSQQAQYLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LER3</accession>
    <name>A0A9Q8LER3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase OpS4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04992</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760420.1">
        <property type="nucleotide sequence ID" value="XM_047904140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LER3"/>
    <dbReference type="GeneID" id="71984870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04992"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="439" mass="48665" checksum="56A2B4C6C5EC7537" modified="2023-09-13" version="1">MTAAPKTNVSPLDIKIVGAGMAGLSAAISCALAGHNVVVLEGARELAEVGAGFQVTPNGCRVLQQYGLLEDLRRSAAEPTLLQVRRWSDGKVLSRTDDFNVEMKSKYNAPFWDLHRVDVQRALAAKAKELGVEVRLGSRIEDVDFDQATIRLASGETLQADLIVGADGLWSKCRQKFLMSKGLEPDIPIPTGDLAYRIVLEVNEVKSQEVKDWISQPTCQFWIGPEAHVVAYSVRNGQMINIVLLVPDNLPPDVSKQSGSLEEMRAIFNHWDPMLNRFLDEVKSVEKWKLMHGAELDSWISPKSNFVFVGDACHSMLPYLAQGANSAIEDGAVLGNILTAVESRSQLPAALKLHEQLRKKRGEAIVRETFAQRKDFHMPDGEEQAKRDELMLGQLGKQIEGKFPSRWQCPEVQPWLYGYDAKEEVERALKAQPLASVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF72</accession>
    <name>A0A9Q8LF72_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760470.1">
        <property type="nucleotide sequence ID" value="XM_047904519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF72"/>
    <dbReference type="GeneID" id="71985249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05371"/>
    <dbReference type="OrthoDB" id="3632761at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058645">
        <property type="entry name" value="NTF2-like_dom_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26534">
        <property type="entry name" value="NTF2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040491495" description="NTF2-like domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2-like" evidence="3">
        <location>
            <begin position="47"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32486" checksum="F2F912106D5E54C4" modified="2023-09-13" version="1">MRSYIGFTTIVAILAALVSAAPSLGFDLFNWNRSESSSPSSSADERCMTPDEAETTADIFRMLIQEYSHELATEALTEDFVDWASSVNIIINKGAAGPKSMDKPTFASRAAFIDGQGKQPQIPFTKIRVWPGCRHVAMRWKTGKSANGHLTEVDDIPVHGHVIIDVVPAEAGNRFNWRIKNIWSEFNSGAWLVNLGVFKPAMLPNADDVRHMREFGDGDGEKQTNTSMMSPEEDGVGHSKEVGDEVQEAPVEKQETPVEKQQSSTMSPNPDAVRHIDKPPGWSWSAEDARQGAAGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF85</accession>
    <name>A0A9Q8LF85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760675.1">
        <property type="nucleotide sequence ID" value="XM_047903103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF85"/>
    <dbReference type="GeneID" id="71983833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03955"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="102" mass="11597" checksum="8FADCB79EFF743A8" modified="2023-09-13" version="1">MAKKAKKAKKTTFLSLPRELRDIIYTLAFNGIATRRDIHGTEHGGLLRMEDPICAEALEICLHKQVQVVVVADFRPKVKGDIGTWLRRSCRCWWSWSASASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFH3</accession>
    <name>A0A9Q8LFH3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03991</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760803.1">
        <property type="nucleotide sequence ID" value="XM_047903139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFH3"/>
    <dbReference type="GeneID" id="71983869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03991"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10004">
        <property type="entry name" value="RPD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="44"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="388"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO16437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="669" mass="72973" checksum="B1D9395997E3C4FD" modified="2023-09-13" version="1">MASKGGFTPLDAPGTGTNAAPSQPKKVAYFYDSDVGNYAYNAGHPMKPHRIRMAHSLIMNYGLYKKLEIYRAKPASKYEMTQFHTDEYVDFLQRVTPDNMDSFMKEQGRYNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRGKCDVAINWAGGLHHAKKSEASGFCYINDIVLGILELLRFHPRVLYIDIDVHHGDGVEEAFYSTDRVMTVSFHKYGEYFPGTGELRDIGVGAGKNYAVNFPLRDGIDDNSYKTIFEPTIGWVMEYYQPTAVVLQCGGDSLSGDRLGCFNLSMRGHANCVNYVKSFGKPTLILGGGGYTMRNVARTWAYETGQLVGVEMGPDLPFTDYYEYYSPDFELDVKPSNMDNANSFEYLDKIKTQVLENLKRTSPHAPSVQMHDVPREPLGMHNAGPDGEPETFEEQEDRLDDEEDDAEASKDRRINQRMWDRNRTGDNEIDESDDEEMAEANGVKRQPGRPRRRGIMDHINPHGPTDDSGANTPVDDDSRSLDGDADDEENGGAMQLDGTADDPLEANAAVGESILAAKASKSPAPPGSLTAKAEPAASDQSEAGAEDEADDEMQVDSVESAQPSAIDRLASEAAAQQTSTPPKSPAPVVANTAAEPSATEDVEMAESAQAAKDEGEAERESEDTKAEASNELATKDAPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFX9</accession>
    <name>A0A9Q8LFX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760845.1">
        <property type="nucleotide sequence ID" value="XM_047903777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFX9"/>
    <dbReference type="GeneID" id="71984507"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04629"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="11802" checksum="83482E6104639AE3" modified="2023-09-13" version="1">MQHPALILVSRSDDAAYRDLRINIKVIVGLLLDLYVRRHPVPRGEKCSDIPNFDLLDPSRLPSTEQLRTRLHSSITTGLQSCGVKHVKRYIWLRSIESNSPVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHZ3</accession>
    <name>A0A9Q8LHZ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762178.1">
        <property type="nucleotide sequence ID" value="XM_047904844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHZ3"/>
    <dbReference type="GeneID" id="71985574"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05696"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="19426" checksum="E45FD87EBB313499" modified="2023-09-13" version="1">MSEELQTLHEAQRLLQAAYDEKRTEEARVKYLENQAFDSWIARLSDLTDRVITHERFKDVKLAERAKQRLKDAIQQHKKARQWDQIRGIREHIEALDIVIEAREYVVDRLMMRVEECDEVHEIEYEKIQMRDTTMEGEMESGGVVGNDRVQGGIGGARGQVKSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI09</accession>
    <name>A0A9Q8LI09_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_06429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762208.1">
        <property type="nucleotide sequence ID" value="XM_047905577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI09"/>
    <dbReference type="GeneID" id="71986307"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06429"/>
    <dbReference type="OrthoDB" id="3787959at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="27471" checksum="04CE9D8003AE12FC" modified="2023-09-13" version="1">MPLLYGEGRHAWQRLQQELIKTSNDETLFAWREGIPGVEKHSCILSSHPRDFALSSATMIYPIVERLPYGITNQGLEIKLKAASALESQVGLPYPGKLLIISLNCCIRSMGNTLKLCLLVLSQRHSCGHYEMIMCTTIGAIYSEPGASCINFKHGTFSMLETLTECGHKMINVHVSSTDSCTTKVAAALRDERCTTNGIRDALFDALEAKAEQNKTHMANCINPDHNPYLDYSDDDSEGQGSKEMSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LID5</accession>
    <name>A0A9Q8LID5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762301.1">
        <property type="nucleotide sequence ID" value="XM_047904706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LID5"/>
    <dbReference type="GeneID" id="71985436"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05558"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15317" checksum="CA89F5DA7B1D47B4" modified="2023-09-13" version="1">MFGGGRGHHGFNIQTTPMVAYIEAFGLFAERFALFITRSERHGAELHKAFVDADSRRSGTSRVVERIDPIAPAFGRGDVEGAVYGAVFVHFASLVTLATAVEADYRSDALNFSQYRAWILSNKPAHISAINQVKEIWGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIL2</accession>
    <name>A0A9Q8LIL2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762421.1">
        <property type="nucleotide sequence ID" value="XM_047905042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIL2"/>
    <dbReference type="GeneID" id="71985772"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05894"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="160"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="613" mass="67725" checksum="35E065D197A4F6CB" modified="2023-09-13" version="1">MATQAAISRQTYPPISSYQTPQSNSPASIHSPQTDAHGRPLYGMGLPQQMYAYPNYMQGQQAHPSPYGQHAANASQHASMTSQPGMLMSHQQPQQQMQPPGPGHPQQPGMLDHKPSQSSLQRPPSVLGAPQQSPGQSSGPAPGPIPATTPLVVRQDNNGVQWIAFEYSRDRVKMEYTIRCDVESVNVDELSQEFKSANCVYPRACCGKDQYKGNRLHYESECNAVGWALAQLNPNLREKRGLIQRAVDSWRNSNQDVRLRSRRVRRMAKIHNRNAAKAPPGGAQFPGPHGPGSAGLPPHGMPPGSARPPNMGPGGPQLHHHHTDATDNGGGSDVSAGDSYNSPAGHPAQPTNGQNELTSPTTGRYTQNFYPSYPQQPGVGGSSMPSIAHGMDPMHTQASTLARPASTSTKKDEEEHKRNLFGDVPESKRRKFILVDDNQRGTRVRVRVMLDQVKMDDMPDAHLRINAVYPRSYFPRQMRSPPGSPHARGNWDDEDDELEEGHVERPAGETMVPVSLMDGSEAKLPVPRMTKSRRNKEVALNELGYRMSWGQARTFNGRTLFLQRSLDAYRNKMRSTMIAGGSETVTIAPHFETRPGKRKWLERNKRSRRADSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIU4</accession>
    <name>A0A9Q8LIU4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_05461</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762656.1">
        <property type="nucleotide sequence ID" value="XM_047904609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIU4"/>
    <dbReference type="GeneID" id="71985339"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05461"/>
    <dbReference type="OMA" id="FKGGSTC"/>
    <dbReference type="OrthoDB" id="416093at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="138"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="48"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="557" mass="60863" checksum="DEE69E6D3E74D0E2" modified="2023-09-13" version="1">MPHNGAPYNVQHALRTVFREVHPSSRVLPGIAQRRHFHEYFVTHLPSSSLAPDKTHPSHHKLPRSDSKPHQGPSERSNRPPASNRDTTIVRIPLKSAKHHFGAGISRGSRPYNEDTYQAGTVEIPAFAKKQPMSINRRPNSDQTQGSTRETGDPQVFYFGVFDGHGGNECSEFLRDRLHGYIEEAALLFGMQSTLQKSDNPSEDNEYSGGIMGEQDPEDLQKTLVSSWKETVGGYFKRFRPEHFPAVTNADQSSAQDNSSIETVLAYAFLKADLDFTTAQAAKQSENAAGKQEQTLQSDPVIDDKPLNEGDMLFHPDRPASQNLSKRPPAKGSSPDLDKPIGGNSRFKGGSTASIALVSTPTPTPFWHPASPSTLIVAHVGDTRVLLCRTSDGASVPLTINHHPSAPTEAQRLRRYAASFVTDSFGEERVLGLANTRAFGDIGSKRIGVSAEPQLTTIQLPPAGYAFIVLVSDGVSGHLEDQEIVDIVKEARTPGQAAKDLISFAVETAGEADNATALVVRLGGWERRSEGGGGSMGTKERRDFRRREADDPRSRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ77</accession>
    <name>A0A9Q8LJ77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761954.1">
        <property type="nucleotide sequence ID" value="XM_047904975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ77"/>
    <dbReference type="GeneID" id="71985705"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05827"/>
    <dbReference type="OMA" id="HEHTFAR"/>
    <dbReference type="OrthoDB" id="10539469at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43965" checksum="BB0972BAFDC9F546" modified="2023-09-13" version="1">MRGNVPRSNFPHPNPDRADGIATDSSSRHYTTHSHHTCTASRTSRRRARSPSKEQLQRRYEALIAARIDVSDYREQAQLEHEELCHELVEISQSQGDILDEEGNAAQSHDPKRLFDLQRSAKRSLDTYNARLANIRQLQRHLAKLEQTLAERDADFVVAAEYFAISRPVRTPVEHSLTSAEVLHSLKADVEILQERLVELDYARHEDEIYRNLLLDRDEVLSVADDDFYKAYSTKREVMQRDLEQAERAVIEHERTVGTQRGPDQFRHIIPSQAQSSWSGQGGQHLDATIAESDFGQPESTKSWPTNSYILPGDAVKRSLRQSKAPSSGSQDRVYDWIDTVRASRDGLAVTRRNSLNDLLTLDDPNRSGAFHLVHQVSVKRRRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJA6</accession>
    <name>A0A9Q8LJA6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762798.1">
        <property type="nucleotide sequence ID" value="XM_047905826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJA6"/>
    <dbReference type="GeneID" id="71986556"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06678"/>
    <dbReference type="OMA" id="FEAQFKP"/>
    <dbReference type="OrthoDB" id="5556956at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027973">
        <property type="entry name" value="FSAF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15375">
        <property type="entry name" value="FSAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="31730" checksum="84725FD92BF2610E" modified="2023-09-13" version="1">MAVALGKRKRRTITEPKPSSHQSDSEDEQDARALFQRAFEAKFRPLDKPSKPAAEEEIEEPEDDSEDEEDWSGLSGDENEDQEEVETIEYAQPSIDDIFSGGKKKFMSSKPPTLGEEDKAQQKHSSKAPPDEEEGAESTNLKNDLALQRLLKESHILDPSSFRTSSALEGKHRLKALDSRFKDLGAKSSFLEQERMPLSHRKGIAAKSSAREASRRKEAAENGVILERVKFKASGEKRRERSVGGPGIGKFRGGTLKLSSRDVSSIQNSGPRRGGGRSGRGGKRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJB0</accession>
    <name>A0A9Q8LJB0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762896.1">
        <property type="nucleotide sequence ID" value="XM_047906214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJB0"/>
    <dbReference type="GeneID" id="71986944"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07066"/>
    <dbReference type="OMA" id="RRAYWPD"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF4">
        <property type="entry name" value="AMIDASE C550.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="94"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="243"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="559" mass="61964" checksum="56C65533E49C2873" modified="2023-09-13" version="1">MPSRSFPLIQTLPVPKGDEAWEARRMQILVDFIEKVPQEYYIPQHYVDNPPLNVTAIPRECGILTSEELEITEMYDAMGLASAIAAGKYTSLAVATAFCKRAIVCDQISCCLTQWFPEKAFEQARALDEHFARTGKTVGPLHGVPVSIKQHISIAGLPSDVGFVSTTVQDENDSLMVSILRKLGAVFYVKTNQPQSIMHLETDSHFGRVLNPYNINLSAGGSSGGESALIALRGSILGVGTDIGGSVRGPSGKVGIYGFKPTSYTLPMRDFINGGFVAELNILCSTGPMCHSLRDMDLFMREVLGHKPYLNDPRVVPIPWTGLQTSVTASPQTRLKVGIMMHDGVIQPQPPVYRALEWAKERLQASSSVELKPYSPYKSAEAIKMIRKMYWPDGGEIFRASAEAAGEPIHMLTEWILKDAEKRDAAGITRDRVLRDAFRCAFAEDWTRQDVDVVLCPVYVGPAPAHDTSFYWNYTALWNLVDYPGLVFPTPIKAGAQGVEQYPDEGSKPWNDQDAYVRKLWRETNYEGAPIALQLVARKYHDNFLFGAANTIKDVLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJD0</accession>
    <name>A0A9Q8LJD0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-amino-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762585.1">
        <property type="nucleotide sequence ID" value="XM_047904901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJD0"/>
    <dbReference type="GeneID" id="71985631"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05753"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001716">
        <property type="term" value="F:L-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF382">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040381709" evidence="1">
        <location>
            <begin position="22"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="175"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="657" mass="73143" checksum="463989510DC7AC73" modified="2023-09-13" version="1">MVRRSRLSAASLAALVSSSSAGSVVPRSATVSFQNGILAEAGGMHNLSLHYGACEAARPDDCHHSLGSTFVGSHPLGKRHEAHPSQRPTKFVWLPPADITDGGCLQVYSGNVLVGRSEPVTVGGRKTKRWQAAAEIMDAEGPWFEGVEYLKAKKPGDVFVAAAKSKKIGIIGGGMSGLMTAHLLDSVGFYDWKIVEASSRVGGRVHTSYLNGTTPDQYQYQEMGPMRFPVSITYDDPAETIQINDHRMVFQLADVLNKQNGNASEYKVNFIKWIQSAVNDPSASATSNATYSNATAVAEAEAAYDRWADMDRDAIRAMAFNVYTAHKWVVDNGYFHFSEAEYLKYAMGLSNNLTDEVDSSLDNSPVWEYDTGYFAATEWRTIDQELSRLPAAFGPQVYNRTYFQTAVSGMSWDAETEKVTVQYRNHSKIAMEPDTMDFDYAVVAVPFSKVRLWRLPEYTSLLSRAISRLNYDQSCKIALHYKTRFWEHLPEPIIGGCGSTDIPMVGSICYPSYQINSTRPGVILGSYISTNDARSVGSMTEEDHVALVQRAMVEIHGEVAAEQWTGNYDRKCWEFDEYQAGAWADPLVGQQELYLPAYFQTEKHTVFVGEHTSYTHAWIWSALESAVRGTTQLLLDMGLVDEAKEITEFWMARWIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P291</accession>
    <name>A0A9Q8P291_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01847</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755106.1">
        <property type="nucleotide sequence ID" value="XM_047900995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P291"/>
    <dbReference type="GeneID" id="71981725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01847"/>
    <dbReference type="OMA" id="IPWGPYG"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF5">
        <property type="entry name" value="MEIOSIS-SPECIFIC APC_C ACTIVATOR PROTEIN AMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="127"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="539"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="601"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO10740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="623" mass="67384" checksum="6ACFDF20352D5153" modified="2023-09-13" version="1">MSLESSRTADPFGPTPARTARMAERYATLRRFPFGAGPPSRAATLVPDARPGSPRAISAGAVWSVGGTIVTEGVASVTDRRGGRVTSGTSAPHYTAGFLHRQTPSEDEVQHSERLAVAMDIERNARMFTTPPSPSASSFSTPRRSHSSSGRSSTYWSNNSWQTDTPPSSPRSSRRKIKDVPAIPFRVLDAPQLRDDFYCSLLAYSHTMQCLAVGLGQHVYLWSENRGTTPTHIPDSLTAPFGAHVTSLSFSSAAGASAILAIGRANGQITLWSPLDFNPRFSSDQPAPVSCVCLRPNPVKRPSVRKPGVMVNTEELLVGDEAGHVYYYSIEWPTQSEVDLFDWQGSMSLLARLECHTQQICSMAWSGDGEYFATGGNDNQMFLYESKRLLRTQGSGTAVATVTVRNGTPGGPTPLVQNGVRAIMPGQEKHLFTLNAAVKAIAFAPWQSSLIAAGGGSNDRCIHFFHAMSGATLATIDCYAQVTSLVWSERKQEIAVTFGFAQPEHPYRVAVFAWPSCRRVVSIPWWGEERALSAVAYPGGPHGGPGQPRHAGDRSIPMSGQARRTREEGCLVVATSDASIKFHEIWPDRSEQGRDKVDRAALGSGSIPEDNLSPTLMRGAAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2J3</accession>
    <name>A0A9Q8P2J3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755376.1">
        <property type="nucleotide sequence ID" value="XM_047900598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2J3"/>
    <dbReference type="GeneID" id="71981328"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01450"/>
    <dbReference type="OMA" id="TCHIKLM"/>
    <dbReference type="OrthoDB" id="9997422at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00138">
        <property type="entry name" value="PLDc_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF22">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="56466" checksum="48B5A90D9EAA7EF4" modified="2023-09-13" version="1">MVDRSKIEQLCYSTLSVSSEYAKDPSKSPGDIAEKLYGSHHLTTITTKTPDSRGTFSKNDLEWAKSCGNFGNTNPSELFLHGLHDVLQCLRHDPMADCVSPPLIGTTGFVPMTIIAPLNDQLRHMSNLIVRAKKEVLLATNFWKTSGASTFVNDALIELSKRTAARNERVVVKIMFDRGALKQIFDNHQNVDSKGWQASGVGLPPPEQMPNVDLAIVNFHRPPLGTFQSKFMIVDRQIATVSSNNIQDNDNLEMMSHLEEPIVDSPWETFLISWHNALKPAAPCRTTSAAQSSPPTYSEQSFTALFEPDGSFRLPEQPCHHDLPEHMPNSPHYDDSIANEIERMRSVLNPAAGEKHCDAVARYLNKPTGLSVKATSPEKDSGLHFFPFIPVPDTEPVPMAMVSRKPYAAMNNDSVFVPQNEAFLSLVRNAKCTIFIQTPDLNAKPLLPALISAVKRGIEVTYYVCLGYNDGGELLPGQGGTNEMAANHLYSELEEDEKPLLKVFFYVAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2V3</accession>
    <name>A0A9Q8P2V3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01544</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755691.1">
        <property type="nucleotide sequence ID" value="XM_047900692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2V3"/>
    <dbReference type="GeneID" id="71981422"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01544"/>
    <dbReference type="OMA" id="ELYNDHA"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="17578" checksum="34647D23B0071C0B" modified="2023-09-13" version="1">MAQNVLLETSMGAIVVELYTDHAPKTCQNFSTLASRSYYNGTIFHRIIPDFMIQGGDPTGTGRGGASIYGNKFEDEIRSDLKHTGAGILSMANSGPNTNGSQFFITLAPTPWLDGKHTIFGRVKSGMRVVQRMGLVRTGAEDRPEEEVKIVSARILQAEDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P378</accession>
    <name>A0A9Q8P378_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vesicle transport v-SNARE protein vti1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_01917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755798.1">
        <property type="nucleotide sequence ID" value="XM_047901065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P378"/>
    <dbReference type="GeneID" id="71981795"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01917"/>
    <dbReference type="OMA" id="MEYEAND"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.400:FF:000002">
        <property type="entry name" value="Vesicle transport v-SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="25534" checksum="774426FFE3A9C732" modified="2023-09-13" version="1">MANPLDTDAGSELFSNYEAELKLVQADISQKLDQIPELQGEPRKAAIAQADRALEEAKELLDSMRLEKQNIPQASKVKVNQRFRNYESDVDAAKRKLKSLHDDRQALFGKRYTDNPTQDDQLEQRQQLLSGTDRLERSSGRLRESQRIALETEDIGRNTLADLGRQRETIEHTRGTLLESEGYTDRSNKTLKGMARRMATNKIITVAIITVLVILIIAVVVSKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3H2</accession>
    <name>A0A9Q8P3H2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endo-1,3(4)-beta-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3H2"/>
    <dbReference type="GeneID" id="71979900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00022"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="417" mass="43138" checksum="124BD5D37BD28A01" modified="2023-09-13" version="1">MFTGTVLTNDCGKDLGFAGCYSSPTKPNNAGTDFNADGGGVYAMEWTSAAIKIWFFPREQIPASLKGPIPPDPTTFGTPDANFAGGCDIDKFFFNHSLIFNIEFCGSWAGPTFVDDGCPALDPTNQWRSCNIYAATNPQAYTEAYWAVNYLEVFTSAPGSPSPTSSFLSTVTPAASSTSVTDSGALGAPTTPTQSLWPPTSITTSSTSTSSPPSSSTEPPPSSSTSSSSSSSTPSPDPTTSTSSISTSSPSSPSPSTTLLSSSISSSSTLTTSTTAASSSPTTSQQPPTPSSTAPQVITIRTTTIVSVPAAPPSTGTDIITIHTTTTVHVPASSPSHHKRAPTGPPPGNDIGPLLRPSHATKRFDPEDPDETRIPVSWTFECCFEYASLPTGKGSASKKSSDDDEHAFPTAHSKAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3H4</accession>
    <name>A0A9Q8P3H4_PASFU</name>
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        <submittedName>
            <fullName evidence="4">Nuclear GTPase SLIP-GC</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">CLAFUR5_00856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900004.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71980734"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00856"/>
    <dbReference type="OMA" id="VAQGYMK"/>
    <dbReference type="OrthoDB" id="3598281at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056024">
        <property type="entry name" value="DUF7605"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24564">
        <property type="entry name" value="DUF7605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="336"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7605" evidence="3">
        <location>
            <begin position="986"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="735"/>
        </location>
    </feature>
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        <location>
            <begin position="1242"/>
            <end position="1309"/>
        </location>
    </feature>
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        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
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        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
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            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
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            <begin position="685"/>
            <end position="702"/>
        </location>
    </feature>
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        <location>
            <begin position="1242"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1309" mass="144331" checksum="240516FD4702F057" modified="2023-09-13" version="1">MTSMEESAKRGQVQHLLHDAVPDLEAFFRKAGRLVVAVRKHHRPFSSNEIVDLQDWVWVKAHGKVPISKIVDAYKNQCAVGDETDISLRMADSTTPTPATTMSALPTQDRLLVLTAAVREPDPPSSQAASSAAPSFNSAMSNSPRPPLHEVNRQLTTPSSRSPVPAMKLNAAAMSNQPAASYNAPPNHLDRVPHPSATSIKAEQSENVDPLPPTYRGHPLASPTSVTAGQAAIPAAQPKEEPEEETQAYAPREQDNPFAASQESEPEQHAPCGQFLQQLSNETTPERLEAGVAAGLKALSELELPLKELAANEDATNWLKQIDTVRKDAARTRTVIGVVGNTGAGKSSVINAMLEEERLVPTNCMRACTAVVTEMSYNDSPNPRMKYRAEIEFIRPEDWQKELHILYKEIIDESGNISREISNPESDAGVAYAKIRAVYHKLTKDDLTRTNPHALMTHKHVKNVLGQSRKIYESDASAFYKRLQQYVDSKEKGTEKLDKNGNVASNQGKRKFELWPLIKVVKIYTRADALSTGAVIVDLPGVHDMNAARAAVAEGYMKECTGLWILAPINRAVDDKAAKTLLGNTFKRQLKFDGTYNAVTFICSKTDDISRTEAFDSLGIDTTELDTKMDEIVSQRREIKKQLRAAVEKKSNHDDAMEDIDDKIESWENLADEVGDGKTVYAPTNKKRKRSSAGGAKKRRRRAVDSDDDSDNKSDDAQSEAQPEEGLSSEPLTEEVVTAKLDELKQLKKDMRREKRTLDDRITELEDELDGLQVKEDEVDAELSARCIKGRNDYSRGAIQQDFAAGIRDLDQEAAADEDPDNFNPDEDIRDYDQVARGLSVFCVSSRAYQKLCGRLKKDNAVAGFTHKDVTEIPKLQAHCKALTVGGRNAGCRRFLNSLTSLITSLALWASDDGTGVKLTSQQRDAEKAFLSRKLKDLEKALDKVVTVTLEDVVENLHEQLFDKMDPAVQSAVDGAQATSAGWGAHKNDGGLHYMTYKATVRRDGVYAGAKGHRDFNSELTEPLLKQLASAWEKAFQRRLPHILQTFKRSATTVLKQFHSAVEARTREKGHGLARIAMLGTQLDAYSAIFGDLAQAAVDSITEGQREINREFTPAIAQAMNPAYEYCTNEAGRGSYARMKAGMAAHVETEKSLMFDSAAKGVRQSLLTLCESVKKTMLDKADGVFVRMQKDYLTLVGVHKGDMKMSREERQLRLKVDEAIADLDGLFQDVLEAELDQLKEDHAAGNVKSETEGVDATRAEDEVTNDDEEDLDLDDTDSEGEGEDAASDAEDSDPPSPTNSNDPGDDQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3I7</accession>
    <name>A0A9Q8P3I7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981686"/>
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    <dbReference type="OMA" id="HNDGKWT"/>
    <dbReference type="OrthoDB" id="5380429at2759"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040352579" evidence="2">
        <location>
            <begin position="20"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
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            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12473" checksum="BE1C257816FDAE86" modified="2023-09-13" version="1">MHFSLTLLALTAALTSVFALPTVPIPDDGSWAPGKYEGPGTPYDNGQWTEDKYPTKRADDGAWYPGKYEGPNTPYDDGSWSKEKYPTKRADDGSWQPGKYEGGNTGYDSGKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3M0</accession>
    <name>A0A9Q8P3M0_PASFU</name>
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        <recommendedName>
            <fullName evidence="10">FACT complex subunit POB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_01843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SSRP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047900991.1"/>
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    <dbReference type="GeneID" id="71981721"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01843"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
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        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:nucleosome binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PH2_SSRP1-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FACT complex subunit POB3"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FACT complex subunit POB3"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Fact complex subunit ssrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Structure-specific recognition protein (SSRP1)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048993">
        <property type="entry name" value="SSRP1-like_PH1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSRP1_sf"/>
    </dbReference>
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        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PH1_SSRP1-like"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSrecog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00887">
        <property type="entry name" value="SSRCOGNITION"/>
    </dbReference>
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        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="12">
        <location>
            <begin position="384"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="495"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00025370"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU364013"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="63728" checksum="AD158AAC503D8D23" modified="2023-09-13" version="1">MAPMAANGVRESFDNIYLNLSKQPGKCRLAESGLGWKPASGGQTFTLDKSDLQSAQWSRAARGHELKIYACNEGVVQLDGFKEDDFDTIAKCFKVWYGAGLEQKEHALRGWNWGKNELGRNELVFNVRNQPAFEIPYTEISNTNLAGKNEVAVEFSLPENGEETGTNGSLGGARTEGRKMGGAVDQLTEMRFYIPGTEKVHRGEDGEDGEQADGEEDEEQNAANFFYETLMNKAEIGEVAGDTFATFQDVLHLTPRGRFDIDLYENSFRLRGKTYDYKISYESAKRFFILPKPDDMHQLLCIGLDPPLRQGQTRYPFLVMQFKKDEEVRIELNMTPEVLKEKYNGKLLPIYEEPVGRVIGKIFHGLTGKRLIQPSSDFTSHHQMSGVKCSIKANEGHLFCLDRAFLFVPKPATYISFDHIASVTMSRVGGAVSASRTFDISVTLKNGAGEHQFSNINREEQSPLESFLRIKNIKTKNEMDGDGGMLAAALADDPDLASSDEEVVMQDRGSADEDSEEADEDFAADSESDVAEEYDSDAKSSGDDSDAEMDDADGAAGSGSDTAEKVERPKKKAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3V3</accession>
    <name>A0A9Q8P3V3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HRR_RAD51_Paralog"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 4"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="37503" checksum="D38BDFC7F2E03CFF" modified="2023-09-13" version="1">MAVIAPPKLAFDLWQPSTNKDQNAEDYFDEDLTQTHLTTGVKAIDTALEGGFDYGVVHCITSSADAGTKELIQGLVSSHIRTSSRASATVIDSTMSFDVRRLYQVLQASMKDASEQETLEVLDRVKITKVFDNVGAVEALAEVEERAKVDGAAATAPQQAAVPKSTIEDSDEEDDMLDSPPKLNQAATEASPVDALSTTPPGGILIIDNISQLFQPIIKNNYVHGQALLSQFLRTVTLLTRRHELCTVILSSASNKPASRDERMSLFESCDVRPALGDELGYLVDVHLYLHQMLAKRLEGTRVQGRYPQKVNMLEVVSDRVRGRYGRYAAFSCTADGTLDDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3W7</accession>
    <name>A0A9Q8P3W7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756562.1">
        <property type="nucleotide sequence ID" value="XM_047901237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3W7"/>
    <dbReference type="GeneID" id="71981967"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02089"/>
    <dbReference type="OMA" id="NTTCSIV"/>
    <dbReference type="OrthoDB" id="3646616at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040379060" evidence="1">
        <location>
            <begin position="17"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="164" mass="18138" checksum="7894ABDB5B761427" modified="2023-09-13" version="1">MLFCFLLLALLGLAAAKPTHFGAKIHYKENCSALIEDDDWIISDLVEFQPKIAHLSPFLAFNVRDINKGLQINTTCSIVLSSGSNSTLHNPNLFHVCENRNMRFQYSNGSIEMSRLYRDPCLGDYPYDSAIAWGHATANFTTTKTAGGSLRTATQVHVPITSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P407</accession>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </reference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_01774"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO12242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="181" mass="20245" checksum="4A35446175EEBF14" modified="2023-09-13" version="1">MDPGASMMAYVVGSTHIPQEATKTCNCRPSVINFCPRTPDLSTTMEIKPLAVTMKDMKSLTNIFSSFNVGSTKKHARKKAKTAKWRETIRVHKQTRAEKKLVRKQQKADKTAKREEKLQLKYGEAYVDPSDVLRKGSIVESMDLEEKKHQFDEDDYKADSIAEGASGEDAALTVVHPMVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P422</accession>
    <name>A0A9Q8P422_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="59664" checksum="2006127764EB7DC8" modified="2023-09-13" version="1">MASAQHVFDIPKLLEIIICQVDAPQIHDLKLVNRSWRDMISTSKAVRRAQVVNSYHNRYWKPSKEPDKMTRHELMEEFVQAMCHARNIVATYSWADWVRVNPALPRVHCTKVGKDVELTIRLPTPAQVRSLQSMNEFVTHPPCMHVTLVGQCWEEGQWLVVTMPPVCCSVWRPEGVRIRDLLEIRDQVEQVQGGQPRGNEEIVATLMIYTHGSKPRDVEEERVRKMYYESPLPRYRKVTHGLDGKGVAAWRKDEGMYWDPGMEAVDAHQIRELKLVNKSWRDAIISSKAIGRAPLVDSYEAVDVSDEDLERMKDDIPAIWTHDTLLNVHYSTPAYDWFEWIRINPGLTKVYAWKWHWRSLDDSAAFKLTIRLPSTMESSTLDCLEEYLTDPPCMTVAVAAFGWQDSTWAVPSCSSTCWVYSETGLKVKDVLAVRDQVDATRGLAGQKTIDMEVMATLRIVSDEIGPRDAIDRMLLASYFEGPLPRYRKATHQLDEAGVAAYNKDKEMQWEPDMDTDGSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4I5</accession>
    <name>A0A9Q8P4I5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor BYE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of transcription elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BYE1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO12899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4I5"/>
    <dbReference type="GeneID" id="71980847"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00969"/>
    <dbReference type="OrthoDB" id="79252at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15550">
        <property type="entry name" value="PHD_MLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21538">
        <property type="entry name" value="SPOC_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055499">
        <property type="entry name" value="DUF7071"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012921">
        <property type="entry name" value="SPOC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR BYE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23257">
        <property type="entry name" value="DUF7071"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07744">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="67"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="10">
        <location>
            <begin position="264"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="473"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="688"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="723"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="769"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021616"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="843" mass="92404" checksum="0A0605C84AA75CA5" modified="2023-09-13" version="1">MPRRTLSTYEPRRSGRATKGQHKNASSSPPPPAGPPQNKPAKGAPKGKPSKKAAKNEPQEEDNEEEEIRCICGNADPNDKRPFIGCDSCEVWQHNVCMGITDDEDDIPEHYFCEKCSPEDHQETLQTLARGEKIWESRNKLWQNEKKMSKNRKSKSRGGDGGKPGWLKKDMLPQSEAPAEEPEPAPPAANGGKDTGTKRKRQEEEVKDEGPPEPEPAPEAKTTKSKSARQDKRRKSTPLESKVVMGADPDTDTALVPIKGLPKERQNVAQALSKIIGADIEKRAKSGTRLPAGQTGSSLGDHYAVRIEYSLHMNHTAGKESYKQQFRTLHANLKKNTGLVEKLMLGSLTADELSTMESSEMLSEDKQRERATMKEALDRQAVAVQEDGPRYKQDHKGYHLIEGEADRQTASASEPRPAVLRASASQDAAGRPTSSRSPTSQGPLSIGTKQAEADMERRASYQAFSMDKIWEKTGNAQSPTANISRPLQPHARRTSSIQVQPQTQGNGAKDDPDIDRMLEDNDDTYSPAPVTGVDAIIWRGKLVQTSEDDAPTVNARFVAGRDLASTVPWQELLPNRLSIDGRLAVQKAEEYLCGLRWSSTSDVAVLALTPYDNASPFNEVFEYFHSRQRYAVIEKDKPHMVKDFYIIPLEAGAELPPHAAMLEHCTLKNPIEERMLLATLIVARAPASPTKQDSTAGSAIGTNGHHLPQHVRQSIGGPAGSPLTAQTPTFPPQQGSPQAGYGASAPNTFPPNSYGPSHLTPPGQPAAYPQQNSPPQNMPPQQSQVEQILGELQYTPTAKMILSQAGNSLTVDQLNNLKTILVEDLNARTDFEALTRKLFADRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4J6</accession>
    <name>A0A9Q8P4J6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757506.1">
        <property type="nucleotide sequence ID" value="XM_047902789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4J6"/>
    <dbReference type="GeneID" id="71983519"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03641"/>
    <dbReference type="OrthoDB" id="10546002at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="87" mass="9644" checksum="170B5E139BFF70F3" modified="2023-09-13" version="1">MIKELAQKRQYLKDNGYLSLQDEREELQKQVNAQSRLGRTGSYRHHGAGALKPVTRHLNSNKPGLAGNNTDSPGKIAKKPKKPAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4X6</accession>
    <name>A0A9Q8P4X6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_02992</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757685.1">
        <property type="nucleotide sequence ID" value="XM_047902140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4X6"/>
    <dbReference type="GeneID" id="71982870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02992"/>
    <dbReference type="OMA" id="MRDYVIC"/>
    <dbReference type="OrthoDB" id="10254737at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="53390" checksum="301CF9B9A8B06AD0" modified="2023-09-13" version="1">MSEQQKPDAPAAQEQKLPPAELKKRAKAEKQARRAAQKEQTAAPTGGPPAEAAAANVETKPTKQGGNAGPAQQKPKGEKQQQPTGAQKQGEQNKGPGGAQQASLPVRNRRGSQSQPAPKEPVKRQENKQVELFSHLYNQPRRHTLEGVSKDVHPAVLALGFQMSSYEICGSSARCVAMLLAFKEAIQEYTTPAGTSLARHLTSHYLSPQIDFLKSCRPISESMGNAIRWLKKLIVEVDPDMPEHEAKDDLCDNIDRFIMERITATDQAIASSASQLIKHGSVVLTYAKSSIVEKTILQAHAAGTKFRLIVVDSRPLFEGKNLATSLMNAGLQVEYYAYAGLARAVSDATLVLLGAHSMLSNGRLQSRIGTASLAAAAHRVDIPVIVCCESVKFSGKVALDSIVINEVAPAEELLLPAKPQLSIPTSKDSRSDEGEETKLKNLHDWKDIQNLQILNLMYDITPAEYIRMVICEYGSVPPSSVPVVHRLANEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5P0</accession>
    <name>A0A9Q8P5P0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758691.1">
        <property type="nucleotide sequence ID" value="XM_047901576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5P0"/>
    <dbReference type="GeneID" id="71982306"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02428"/>
    <dbReference type="OMA" id="PDYRANG"/>
    <dbReference type="OrthoDB" id="10456193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="62821" checksum="E762E0674DE34FA5" modified="2023-09-13" version="1">MQRDQTSDLSGDLKNVHFGSATRAPVAPMLSLYCVSSAMDVDNENRTTQIADSNALTVPPNSPWQPLDVARMTQPPLNTEPQAMVTLHGFFGSEGPAAQVKGTPTALQTLAMAISNDLKVFTGASDGDMIVESALLPLHIRGVVPDYRANGILEVQDATEAAALGLTPDQFALSPEEMRVLDTAYPPFLSQIRDDSKYFDIAKLLVMLKVFARYFQHTGKRYQVLVLTKMEGTQVLDAKVFSTQEGANETVFLYRNITFNGFFGGAPSYEEAWMPISLGHDAPRPARELDILGRPAGQYVDQYEKQAIRQPSKTKKPKRAPAPQNTTPAQSSGPRNRAKPIHSGIDVSAYHGMTPAEVFTAVEQELAAGTITTDEVAGERLLLFAIACSNREIRDLLHPYCERNFETLPSDNNVYNGRILPAIKRALKPGQSFEKAKVEFDDARKAHNLKTTSGLRGKSTKEVKISSLPRKSQRAVKYDEPADEEPEADMSDDDMVDDGEATPAPTPRPTRSTRGAKPRASYRATADESEDEEMDDADDTEQDRAKARYKRAKMDKDDEDDEDADFELDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6B1</accession>
    <name>A0A9Q8P6B1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759336.1">
        <property type="nucleotide sequence ID" value="XM_047907421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6B1"/>
    <dbReference type="GeneID" id="71988151"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08273"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="8">
        <location>
            <begin position="41"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="6">
        <location>
            <begin position="276"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="6">
        <location>
            <begin position="300"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="47147" checksum="05147A3A90DD0075" modified="2023-09-13" version="1">MHFPGDRHHQHTTSMANENDMVPRSMPSALKFELTAKCSTTKARAATLQLPHGPVQLPLFMPVATQASLKGLTPKQLDETSCRLCLNNTYHLGLKPGQTTLDAIGGAHKLQSWPHNILTDSGGFQMVSLLKLAQVTEEGVRFLSPHDGTPMLLTPEHSISLQNSIGSDIIMQLDDVIATTSPDHARIKEAMYRSVRWLDRCIAAHAKPETQNLFCIIQGGLDLNLRRECCKEMVARDTPGIAIGGLSGGEAKTEFCKVVSTCTDMFPIHKPRYVMGVGFPEDILVSVALGADMFDCVWPTRTARFGNAITNSGCFNLKNAQYACDFRPVEEGCRCVCCRPRSEGGLGITRAYIHHTTAKETAGAHLLSMHNVHYLLDLVRRAREAIVTDQYPTFLKDYFRKLYAGDKPKYPAWAVEALGGVGVDLLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7B0</accession>
    <name>A0A9Q8P7B0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7B0"/>
    <dbReference type="GeneID" id="71984941"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05063"/>
    <dbReference type="OMA" id="IAQCFIA"/>
    <dbReference type="OrthoDB" id="3648067at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="649"/>
        </location>
    </feature>
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        <location>
            <begin position="686"/>
            <end position="748"/>
        </location>
    </feature>
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        <location>
            <begin position="809"/>
            <end position="889"/>
        </location>
    </feature>
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        <location>
            <begin position="985"/>
            <end position="1054"/>
        </location>
    </feature>
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            <begin position="1068"/>
            <end position="1107"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
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            <begin position="25"/>
            <end position="47"/>
        </location>
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            <end position="181"/>
        </location>
    </feature>
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            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
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            <end position="618"/>
        </location>
    </feature>
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            <begin position="704"/>
            <end position="713"/>
        </location>
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            <begin position="715"/>
            <end position="734"/>
        </location>
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        <location>
            <begin position="827"/>
            <end position="836"/>
        </location>
    </feature>
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        </location>
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    </feature>
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            <begin position="1088"/>
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        </location>
    </feature>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P859</accession>
    <name>A0A9Q8P859_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04033</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761211.1">
        <property type="nucleotide sequence ID" value="XM_047903181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P859"/>
    <dbReference type="GeneID" id="71983911"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04033"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="90" mass="9707" checksum="37BB0B5EC064C54C" modified="2023-09-13" version="1">MVDIEDTGTAQVTFTKSQITATWTAAEDLTILQLAERAGLKPKFGCRSAICGTCESKIVKGQVYGPEGDRPQGVFICQSRPATTEVEIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="31834" checksum="071BB5D8302010CA" modified="2023-09-13" version="1">MAKTKKPKKARLTPKANVPPTPGSSVTDTRVDKLAVAVGNLTIKNKLDFSKALIKYRPPKLAAPAVFGTYELVEQILLSMPKPRSKTTMKTILLSQRVSKTFRGVVERSKAVRKVLFFEACDDFDKMRDYVTWNPLLRVTESLEERTVRKSHLTSSDGDGYLSINNVLFLGPERLSKAHGTKGHQSESWQKMLLAQDEVEPAYINTCTKVNGRSLSLARTLDAEHTMGRVADLLRLKFEGVKVREYYDGDDEDTAQYLAEIEGRQAMDAEEDDDGEDDEAYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8K4</accession>
    <name>A0A9Q8P8K4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71986096"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="148"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="423" mass="47680" checksum="FC17B1C4339BF606" modified="2023-09-13" version="1">MTCQLLVDIADQRCHCVSIPWSPKQGSFHQCVQIELYWHTMTDEAWDSLISLVIVIWDCGETSFDLCKPEGGAIPLPLRPVYGEVHADPLGPAAVTLYRRWLHDCASEHPACPDTTSAPLPTRVLDVRSGSATGDVKLKCTNHERGDFIALSYCWGGVVPLRTLSTNFASRIERIRWHDLPRTFQDVVQLARQLEIPYIWIDALCIIQDSAEDWATESAKMAEIYGNASIVGIAAAAPSPNTGFLGMRENHVWEQVTFGPPADERCLLLRETCEHSANMDPGSKLAVSDRGWCLQERLMGQRTLIFRQEEVVWECRQGYRCECSSAENGYQSLPVYQNRGSVLPTPQRYPRDTSTNLFESCSQAYDFWRNAIQEYTQRLMTKATDRLPAISALTKVIGEDTGDEYIAGLWKNDILHGLLWTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8T4</accession>
    <name>A0A9Q8P8T4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA (cytosine-5)-methyltransferase 1 replication foci domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761915.1">
        <property type="nucleotide sequence ID" value="XM_047905206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8T4"/>
    <dbReference type="GeneID" id="71985936"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06058"/>
    <dbReference type="OMA" id="NGPRDSW"/>
    <dbReference type="OrthoDB" id="5382953at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="63111" checksum="AE002073566A51EC" modified="2023-09-13" version="1">MSLETGILKPRHPSIEDTDQWPEFMLNNVHVHLPDDPEATANLLEAAEGYPLTVVGQLEPLDEEDAHLYAHEPTTKRVNIILENVYTFSYGQYGDGSTAIWAAGKAGWYTIKPGRRYKATYSDMVDAVNVLYFVADAYREERKAGKGKSAKILPDYSAQELFAKYAAEELGSEDAAEGADKIYEYKDFLISSMIAGKEGLSWSKFPLYKHLFVKFPDVWAEMKQRQTPRPPKPESQKSRAKTTRRESIETTDSAKKQTFTAKTRTTRQGSVDTISTASSTRQRRGNQQKKVSRPVEVISLDGSSDAGSAARNTHTRPKTAGKGTKSTSRRTRATSEAISEEEHDSQEMDLVETPTKDDDSDVETKLRARKNKSSLRPRPSKAPKSTTRDGGKRPAPGEHDDDEELPPSPTGKRRLADVDDARPTSKRRNSRQHLDEGIDIPTSPSNSGEADDASTPDTTSNLVNVPIRSLNHLDPVQEDTWVCALDGCAHKVYAASSPEAQLLIKQHYNLHAFDDDERIQMIKKMQAPSLPASRLMERVKLQAKAEGFPGSHQMAPRFPAIGVTQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8V1</accession>
    <name>A0A9Q8P8V1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_06482</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8V1"/>
    <dbReference type="GeneID" id="71986360"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06482"/>
    <dbReference type="OrthoDB" id="3649918at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
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        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="15">
        <location>
            <begin position="26"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="16">
        <location>
            <begin position="109"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO17503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="59916" checksum="EC8355A6AB0BAD4D" modified="2023-09-13" version="1">MPLHNYQLCQNAQGDHDTFDTNTTKRDCFQQVLPRYGCTAGDSPCFCSNGNLTASMTACVLANCTLADRLPAQRFKADTCNEPVRDRGGLSRRLCWAMFVIATLLVLCRFLSRTPVLGGQGYSWDDWTVLFCYVLLVPTDVTAEIEVQNGLGMDMFMLSVDQIVTVLQMFYLGELFYNVIVMGTKMSLVLLYLRIWTADSVTPAFRIACWTLIAILASTAAAGAFAIIFQCTPVSYAWLSITGEIQGKCIRIGAFTYTFGALNICYDVIVFFLPVHSLLKLRITWPRKVGVIGAFLVGFWVTICSIVRLQYLVRIDDSQNITWDFQYIGMWSLVEANFSVVCCCMPAMAGLAQRIYAWYWDSELTFSDDPREAMKDLETNTTDSSQHRGSNTGRVTDVEMMAQKAAYHARGDMDDEMGISTGIDHHAVISAIMYRDRPNARNVVNISHIPPNQASRTLLRYRDQHDILHEVEIIDRPQARMSGREIADLEQAQLDNDPLPEAKWQRAEWELCERDTSRAPSPRMQRFPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9M7</accession>
    <name>A0A9Q8P9M7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762472.1">
        <property type="nucleotide sequence ID" value="XM_047905435.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71986165"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06287"/>
    <dbReference type="OMA" id="EERPAYE"/>
    <dbReference type="OrthoDB" id="2163491at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF4">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="3">
        <location>
            <begin position="1065"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="930"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="950"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1104"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1113"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1238"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1247"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1251"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1253"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR632852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1290" mass="141651" checksum="7499C825B8414D5E" modified="2023-09-13" version="1">MVSTSSARLAERRSLQQDSEPRYTVEPQEEFEAMIPAAPEPAKKSQPNDSKRTSWTKAPKQASTSGSQKKAGQQTAGAGKKRKAEVQPEEVATTSTRKRARSSKSDNTTAAIPPAPRKKGTSCADCRKRRIRCTHDLPAAETSTAHSKAKASTEVGSGALGRDAAALTRSPKPAPRRAATVAAAEDELPDAEDEAPHPEGSHEPDMSGVSMATPSTSQHSEPNSSPASHDPTSTTPPSSVSAIEVDVTAQTPPSKQAALDIDNAHVSPSPASSVLSSVPSDVMDLSSPDELRRDSKTNEKDSGGEIVADQEAVATDIADKDQATSLTDKEKRAESARKGWLKRKQNTAQATAIESEDLDQVRPLTAKEKKSASARKSWVKRKQNAAKIAEATSKKPTKRKTPARKASSSKQTKLVTLMLPKPTSSGTSKPRSTLQRPDPITPQPKASQQENGLPTPENSQAKAHVEEATSADPLLRQLAEKLTEREPLASKPLPQGQPLVWADSRQALCETVPYFKMPQSGCHQNDRHVYAFLFDSIGHCREYMDSDVIIARAGGGMEADASGQIVQKKHHLMTEAQVQAVLNDIELQNPLVLICGDRSVGAVCKMPHKYNVLGWFKPVSVWAEKTLGKGGKKWTTIKYRFERLNDSKPAWHQPEEQMVTDEDRQLAGDLTHTPCPECHRTFAHTYLCGWMCLNPDCDQFWKLEDGGDAPYGKLLYNPAFLLDRTRWAKEEEPYSVRPAVPTVGNTVGDNLTYINTRGICCPECGRCSSRRLFKGWRCDNPSCTFENFPQHIPVTPPMLHNPWENSGDGPALARNKHEGSHGVNVVVTHVHGFKVFTYTIAGVNGKFVHAVSNAKINREPRGPDEMFAAIQGQDEPGMDMHLERRRFGIEKMPVNKIESQTVPPVPAMPAAPSTPLRQSTLRFDLELDTLSLQRSSSSPVSPEKIGGQIGRERSSRLAERCQKAVSPNLADSASSTNAMEPAHVTPTNDESQSTPDVAAEMTENDNGSFLAGIEEAAEADEPQKSDPKDTTTVGKPVVEDGDLMTAFSINYGMPYKFVAVGSSLPFTDSPWPVRTCRADLNWASQTFLDSQDHMDFNEELIFAYLEGQKIEYHDDGESGLGPRIATLSLGGKAKMHLRMKMKHYTGCSKTGIFTAEKPMPHSIDGPEMYQKRLAAWNELQTLKATDKPAYERRRKELPKELGLFSKRMKKAEDLVTVTLNHGDIVLMEGYEIQQYLEHKVVPEQCLRFALTCRTVLPDHLKPEERPAYEVELDDGSMSCLRGMVARDTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9P9</accession>
    <name>A0A9Q8P9P9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phospholipase A-2-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762653.1">
        <property type="nucleotide sequence ID" value="XM_047904780.1"/>
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    <dbReference type="GeneID" id="71985510"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05632"/>
    <dbReference type="OMA" id="DKCIYYW"/>
    <dbReference type="OrthoDB" id="10265988at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:ubiquitin recycling"/>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
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    </dbReference>
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        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="ARM-like"/>
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    </dbReference>
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        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="11"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="188"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="233"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="7">
        <location>
            <begin position="375"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="8">
        <location>
            <begin position="504"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="788" mass="84845" checksum="B27F2C514EF4C26A" modified="2023-09-13" version="1">MSGDFKLSATLRGHEEDVRAVVFPSSHHLFSASRDNTVRQWTLTSPKPPTYDDTIALSGSHWFNALAHAAPSKAHPNGLVATGGKETFVFVKNVGQAPEEDPHRLLIGHAGNISCLAFNQDGSKVISGGWDSQVFVWDVEAGNVTAELTGHGGPIWGVMVFDEKLVLTACADKIVRVFDINGKALGAIQGHTDVVRCFCKIPDGHWSGAAFASAGNDEVIRLWGIEGTSMGVLDGHTAYIYSLAILPNGDIVSSSEDRTVRVWRDGQCIQTITHPAISIWTVAACPETGDIVSGASDKIIRIFSRDPERQAGAEAVQQFEESNRMYAIPQETAAQGEPFEKENLPGPDALQTQVGQKEGQQLFIREQDGSVTAHLWSASTSQWNLIGTVVSGQGTGSAKKTYNGKEYDYVFDVDIEDGKPPLKLAYNLTESAWDAARRFIESNELPLSYYEQVANWITEQTRGAKIGQDSKPATQPGPAASDPWGSDKRYRPGDVGSASVSGQRKIPQRGYLTIIEGNPTNAINIIVQKSEELSSSGQISSEQALQPDELEDIKKLPTQLQNKQDPRPTAAQISSLLKVASQWPVKSRVPAVGVLALLSVASSFVTATSSGDDTIVETVSRAGLLQAQQETTNNVVHAIRLLVNLFQTESGRLIVDGTLDAVLKLVRPFAAQPESVAQAKALSTLYLNFAVLLTEGASPSEAQMREARATLLLTDIAMLLESDSPHAGDGDVVYRALAALGTLCSLGNEFRARLEGGVAGTLHVVATKPGSQLPNTKELIQEIRDELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9T1</accession>
    <name>A0A9Q8P9T1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762652.1">
        <property type="nucleotide sequence ID" value="XM_047904783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9T1"/>
    <dbReference type="GeneID" id="71985513"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05635"/>
    <dbReference type="OrthoDB" id="5409365at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="180"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="51398" checksum="BBFC75241D6B39F6" modified="2023-09-13" version="1">MYLENNLIVEVVDSSGTPLKEWGQQKFGDKRLSCYVQSETGMSFGLRLVPAASIRSEMDDRRAETKRWYRTHSQDQEAPLQPFDFLATLRLDGRETPEKCNIVYLDPANEWYRTPSGEIDMCGKMIRESKDSDVHFHKWVFQEVGIESMIEELSLQFDTQVPEPEDPLVKAMQDMGSNNLADKEETAKAGVIEISIQRVIIEQQTTQRPWDANGSTSPEAAGGSKTDRNISHTAGRTAGKKASSNIGTFVYYNPIDADDKPYAVFKFFYRSEEVLRKFDFRGFPSKQIKPDAVALAKLGLGDAVSKRGTAELDHDSDSDSDNDEPTQRRNGGRKTRKAKKKTEQDSPRRLHFPDQAAFSEDEDIDEEEVSKRLEEDDRSRGVSKPVFIDQPVAGPERAVLSNIKEHVNGNLAQPTGADSANKLIETKQLTADEVVQQKPDATKEVVQQTDVESDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC3</accession>
    <name>A0A9Q8PAC3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06704</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763147.1">
        <property type="nucleotide sequence ID" value="XM_047905852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAC3"/>
    <dbReference type="GeneID" id="71986582"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06704"/>
    <dbReference type="OMA" id="WHLIDIA"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF17">
        <property type="entry name" value="NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="47683" checksum="F00FC25C04718C17" modified="2023-09-13" version="1">MASKPTIAVIGSGWGGFTLAQALSVTKYNVAVISPTRTIQYTPLLASAAAGMFNFRLAEEPIRRQNKLPGLQYYKATVEDINFKEKTLHCRPAVPDIAEEHLKAQNPFELKYDKLVLAPGCDVQTFGTPGALKHANFLRTTNDARKVQQRILEMLDAASTPGLTDAQQRDILRILVVGGGAIGIEATAELFDLWHHDLRHIYPHLDGKLSIEIHDVAPGLLGNFDKRLGEYAAQKLEGRGVEVRTSSHIEKVEAGAIWTKELGEEKYGMLIWATGNGINSLVDKLDVKKTEKLPRIMTDRRLRVFNKYDHLIDNVYALGDSANIDGYTLPMLAEVAVQKAEYLAKELNAADEPRSPFQYNSRPNIAYLGQHDGVIGGREEWTGQSAWIAWRSGSIFHWPRSWRRTLMIGISWVFNRIGGRDIARKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAF5</accession>
    <name>A0A9Q8PAF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763239.1">
        <property type="nucleotide sequence ID" value="XM_047905888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAF5"/>
    <dbReference type="GeneID" id="71986618"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06740"/>
    <dbReference type="OMA" id="WRDKSHE"/>
    <dbReference type="OrthoDB" id="10456980at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="24653" checksum="ED57F7728741036F" modified="2023-09-13" version="1">MPRKQLAAPSQWVHDHSAATYSATDFSKFLTQHSGLWEEWRDKSHEPGYMMPMTWLSAYGPAGATHKDPWMKGTPKSQKQRFAYPRKAATPSSDSDDEDGNAIESPSPSRPVTPMPATDDNDVHPQTPAARDRQLSTPDPTPARQHTSTFNHDTYDKMVNTELQTKHNMRKMADDLQEALDEGQAELNGTPPQDLARRHAEARLASLRALQENCLHAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAM3</accession>
    <name>A0A9Q8PAM3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature viability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763347.1">
        <property type="nucleotide sequence ID" value="XM_047906012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAM3"/>
    <dbReference type="GeneID" id="71986742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06864"/>
    <dbReference type="OMA" id="TAQHFTL"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="57664" checksum="601114DADC9898C1" modified="2023-09-13" version="1">MPRQKPFSKKDGAVHFQLLHRAQNDPLIHDESAPSMVFAEIEKTQPRQQRREDEYASSSAASQYSGASYRSYRSTKSKVRGDLEDEFGMSFKQNEGEAAQHGVFYDDTQYDYMQHMKDLGTGEGAVTWVEANLPQKDKGKGKQRLEDALRDMDLDDMRSVGQSSMTSSVARSLLPEEVLPSEFVQKRSYQDMQDVPDEIAGFQPDMDPRLREVLEALEDEEYVDDEEDIFGELTQDGWEVDRDEWERLGEQQMFDEDDDAGWESDDTIKAPTSPPSTSDLPDPNLPLPAGEDAAPPEDPQAVPTADPTHGAWLDEFKKFKKAEKDDKPEKAHQGFAPSTLESSALSSLATGRKKKRKGAQTSTSNYSMTSSALVRTGQLTHLDDRFDKMEANYSLAEFPEEEEDDYLADTGSMASGMTGMSKASRVSKYSTTSGMSGVSGISSYSRATDSEAPKLVRSDFDSVCDEFLGSHSKVGKNARRVRRGAPQSGIEQLDSVRRELGDPKKFISNRYRSTKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAR3</accession>
    <name>A0A9Q8PAR3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_07734</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763356.1">
        <property type="nucleotide sequence ID" value="XM_047906882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAR3"/>
    <dbReference type="GeneID" id="71987612"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07734"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000095">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="26"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="434" mass="48092" checksum="B12539C8B8733D64" modified="2023-09-13" version="1">MRMERMEAPTMRPLPGRSCTFRTGISVSQSYVQKQYRAHGLTGLPADGRNYQPQDLPIEKLTHVLYSFANVRPETGEVYLSDTYADLEKHYPTDSWSDVGNNVYGCIKQLYLLKQKNRNLKTLLSIGGWTYSTNFPQPASTEAGRAKFADSAVTLLKDLGFDGLDIDWEYPANAGEAENFVQLLQACRSALDTYSQTLPNQPHFLLTVASPAGPDNYSKLMMPEMDALLDFWNLMAYDYAGSWDKVSGHNANLYRSKTNPNSTQFSTDEAVQYYLSHGVAPDKLVLGLPLYGRSFVGTTGPGTPYTTVGEGSWENGVWDYKVLPQTGAVVHYDNETVASWAYDATTQTMVSYDSPEVVATKVDYIKQYGLGGAMWWEANGDLPVNNTASLIRQVAKSLGPLQEKGNVLKYPAAAYENIRAGMKSPTKVAKGYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAX4</accession>
    <name>A0A9Q8PAX4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5'-3' exoribonuclease 1</fullName>
            <ecNumber evidence="6">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07249</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763483.1">
        <property type="nucleotide sequence ID" value="XM_047906397.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71987127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07249"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016494">
        <property type="entry name" value="5_3_exoribonuclease_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006743">
        <property type="entry name" value="Exonuclease_Xnr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="11">
        <location>
            <begin position="724"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="12">
        <location>
            <begin position="921"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="10">
        <location>
            <begin position="1168"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1293"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1321"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1353"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1369"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1408"/>
            <end position="1424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1432" mass="160820" checksum="1F1E1FF7C98A2412" modified="2023-09-13" version="1">MGVPKFFRWMSERYPAISQLIAENRIPEFDNLYLDMNGIIHNCTHNNADSATKARLSEDEMFIKIFNYIEFLFGKIKPQKMFFMAIDGVAPRAKMNQQRSRRFRTALDAERARDKAIADGLELPKEDPFDSNCITPGTEFMARLTRQLKYFIAKKVTEDLDWQGCEVVLSGHEVPGEGEHKIMEYIRQAKSQPNYDPNVRHCLYGLDADLIMLGLLSHDPHFCLLREEVTFGRQSKTKSQELEHQNFFLMHLCIVREYLELEFQELKNPENMPGVTFDMERVIDDFILMAFFVGNDFLPNLPHLHINEGALALMFGVYKKVLPKMGGYINEAGVINLKRLDVLLEELSHVEYRFFEAENSDANWLKDKSFQKEDVMDKVKKKGIQTITTGQKELYQKVKKYVNSRASGGDDQALDMPASLKAADRAFVEDLARSLNLQSQSVLDDEGNRHLQLSFPSRPDMDEDEDDDEDEEAQNALLRVFKQYDRAKIEDVSASEAQQKAQEKYDKKFHDWKDKFYTTKFEWGLDDEAQLRELTENYVQGLQWVLFYYYRGVASWPWYFQYHYSPMISDVRKGLGANMEFQLGQPFHPYEQLMGVLPDRSKKIVPEVYHDLMTNPNSPIIDFYPRDFELDMNGKKMEWEAVVKIPFIDEKRLLSAMAPKNAMLSADEARRNEFGVSLKFAYSPTVDYTFPSSLPGVFPDLEHCRVVENIFELPVMDGLDVHTGLVDGVKLGASALAGFPSMRTLPHTGQLGFHGVSVFQQESRNESMVVTLSEGEEKGTIAHAKQRLGRAVHIGYPFLQEGKVTSVTDEMFTYRLQDPDQPATEQNIVQQPHEGRGIEDWKKKANRIESHYSKRLGTIIGTVESLVQIEPLVGLRKTELGATVKEYAPIQGIEPDYATQTVVDQVISEDQRFIEQAALRIEEEFPPSTRAFYLGDFAYGRPLQVTGHQTGADGVPKAEVWVSQLVNREPEFGLDIAMQAERRNPYTPAFLVARQLNLHPLVLSKLTSAFMVQSSGLKLNLGLNLKFEAKKLKVLGYSRKSESGWEYSPRAVELLKQYMINFPEFIARIAANPSGDGWQDTHFYPDPQEAKLKMKEIGQWLKNVQTKGFEKVPLEAEQLDGDTVLAIEQAADAFNATSAQNTSGKQLKNVPRVALLKPSDAEQRTQHQRYRLGHRVVYVLDSGRVPIAMRGTVVGMTRTTRSTLLDILFDSPFMSGTTLNDRCSPFRGSTVPHNAVLNLTDKQVIAMSQAAKDRAPVSNFAPIRGGHAALASAYGMPGGPQLVQANAPPALRGGWRGAVNGHQNDTPRGRGPRGRGGGLGSTQQQQTLPIHNGPPRGRGGINGATPNFSPRGQRGGRGGAANRGGYTIVDNSDPSEGVINNNPKFRPQNYSNVPPPAGLNERGRVRGRGGGAGRGRGGGAAAGRGRGEVPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAY2</accession>
    <name>A0A9Q8PAY2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763496.1">
        <property type="nucleotide sequence ID" value="XM_047906168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAY2"/>
    <dbReference type="GeneID" id="71986898"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07020"/>
    <dbReference type="OrthoDB" id="6287070at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
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    <proteinExistence type="inferred from homology"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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</entry>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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            <dbReference type="EMBL" id="UJO20162.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <sequence length="62" mass="7110" checksum="6B5EEEE5F5F5DC01" modified="2023-09-13" version="1">MATPAVSVTKEFKIFRYLDLPAELQLRIIYFTVTSPDIIDISDDDDMQTAIAQPAKMCCWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEH0</accession>
    <name>A0A9Q8PEH0_PASFU</name>
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        <submittedName>
            <fullName evidence="8">Ethionine resistance-conferring protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71990921"/>
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    <dbReference type="OrthoDB" id="2126698at2759"/>
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        <property type="component" value="Chromosome 8"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="671" mass="72737" checksum="1C4D2C76546B57BC" modified="2023-09-13" version="1">MSHSEPIKSPTGHRGRSESPQTSRSFGTSYRSQHGGDSRIAAIAEEAIAQDLQDGEFTEDDNVQDGGELGAALSRTNTRDMPDMGPHSMTGYHRRPSYMAATPRPFLGTQQPESIVPVEQDWEAAIGEERSLLRDNNLIPPKHPRNRRDGESSQGHGLRKVLSMSFSGRKKSVVAVDEEDGISPSETTALLPGGRDPSAPYGGEDTPENIAKKWEEAVEAGKINTTWQRETKVLSRYSGPLILTFILQNSLTLASVFTVGHIGKNELGAVSLGSMTANITGYAVYHGLATSLDTLCAQAYGSGNKKLVGLYLQRMVFFLWAITIPIAIIWLAGTEILDYIVPEREIAELAGAYLKVLIIGAPGYACFEASKRYVQAQGRFDATLYVLLIAAPLNILMHYLFVWVFKWGFIGCPIAVVVTECLMPLLLFLYVRFVGGMECWPGFTRKAFTNWGPMVRLALPGLVMVLAEFLAFEILTLASARISATHLAANTVLQSLSVLTYQLPFPLSIAASTRVANLIGAGLPQAAKVTTKVTFIMGIFIGVFNMVLLSSLRSYIPWLYTSEADVVALAAATLPVCAAFQLFDSLAAQCNGLLRGLGKQEAGGYINLFAYYVIALPLSFGLGFGIHWDLIGLWAGPALGLGIVSAVEGIYIYRTSYEKASEEAAGRNAQG</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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            <dbReference type="EMBL" id="UJO21502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="28831" checksum="BE9D7EA5B45F53DD" modified="2023-09-13" version="1">MDTSDAAERVAEKVRDLLTRNLREEFPCLKTEALEKLVKDSGNLVKSRVQEQAPIMAASKAHMSFMSLPPELRNNIYEIVLLHPGGLDIQPVTMVRGNRMRRFKPEVPTSRVPDIARVPRQIRQEVLSLHYGLNTFSVHVDSRNIKAPHHSRGMPRESIAAKAHKWLQHIGPQSAALIRDLAIVIPLSMDECTCRGKCIRGGRCRAWHLPGPEGVARLLKLHRYGVPLSSIAVQVGPLVEVDGEKILWQEAVKALGPI</sequence>
</entry>
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    <accession>A0A9Q8PFN9</accession>
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            <authorList>
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                <person name="Chen L.H."/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_08962"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20497" checksum="80F2E0D567F477F8" modified="2023-09-13" version="1">MIDSPTEYAGCTCVETAFQPLRGLSILTGKVEILDSQRVPQVIQQKITALWDQPTWSGYDTTPLQTWTSTIKRAEACDSLDHSLQNLELIDLPEQKTSTQESNGAVTAIAVSLNEIRNKFRYGHKDFITPGTERSVIEPYRDLETALDRLDLDEVRREVMEQVMEKARRDLGGLGDVISRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY8</accession>
    <name>A0A9Q8PFY8_PASFU</name>
    <protein>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
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    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Samaras A."/>
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        <location>
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            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="20981" checksum="2EA662756298F56F" modified="2023-09-13" version="1">MATTAQGRPQVNGVARRQSAPRAPIKKPYQPAATQGKKAMPNGAARAPPRTAPPQKSASIAGESPHNGVTSAYAIMASRIANRVAEMAESITFVERPKPQEPELTAQPEERKRPRKLDIRLNNGSSDHVAFSAPFLDNTLQKMLQLQNRMLKTTADLAKAENVDEKVIKEQAAQAAELSRIIALICAEKARQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGC8</accession>
    <name>A0A9Q8PGC8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hps1-dma1 cluster oxidoreductase toxD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766286.1">
        <property type="nucleotide sequence ID" value="XM_047908476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGC8"/>
    <dbReference type="GeneID" id="71989206"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09328"/>
    <dbReference type="OMA" id="MEVITTC"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="122"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="459" mass="49819" checksum="AC9068D306C00AEF" modified="2023-09-13" version="1">MNNILPKTATELNPGETKLPDDAPEPEGAHDVQMSDAKEVSKDNISKRASREIPDQNFAEEVTVGNREDDPQIKVTKKDQAQSSKDDDDEAQVSDIDEPKEETHTITIEIPEKMKAIKIIEGNKAEIQSVAVPALRDDYVLCKVNCVALNPTDWKHIDRIGKPGSTVGCDMAGMVLEIGKDVKKEWQVGDRIAAFVHGGNQSQKEDGAFGEFCVVKGDLGLKIPDAMSDTDAATLGAGVITCGQALYQGLKLPLPGDGMEKYGGFLLVYGGSTASGTLAIQYGILSGCRVITTASTHNHPLLKALGAEEAFDYKDPGCAKKIRDYTKDDLRKCLDCIAEGNSPKICEESISSQGGTISYLLKTTHTREDVENIRTLGYTIFGETFEKFGIKSEAKPEDFEHAKKFYELTQKLVSAGQLAPHPAEVGKDGLKGVFEGLEKLRKGNVSGKKLVYRVGQTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGQ3</accession>
    <name>A0A9Q8PGQ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_09777</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766463.1">
        <property type="nucleotide sequence ID" value="XM_047908925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGQ3"/>
    <dbReference type="GeneID" id="71989655"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09777"/>
    <dbReference type="OMA" id="KKTHDMY"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="199"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="400"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO22097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="579" mass="63830" checksum="EB9D0802A3167D6F" modified="2023-09-13" version="1">MAKRSREEADAVLDVSEISSKKLKKDKKEKKEKKAKDSTPTVAGANDGDVASEHKAELSKEERKALKRAKKEALKAVEAHEVAEEVADAGIYDEAAAKAEKKAKKRAEKAAKNAAKAVDAVERSDEIEGAAHEDAEHLSGVGKAEADAYYKEKHIAIEDPLKQSVGPILSFGTLPFDETRRKAYFAGFSTPTPIQAASWPYLFNGRDMIGVAETGSGKTYAFGVPCINRLKKDKKIQVCIVSPTRELALQIQEQMTKLATPRGLKAVCVYGGMSKDDQRHQLKGCHIVVATPGRLNDFIGDGTIDLSNVNYLVLDEADRMLDTGFEQDIRKIITAAADGKDRQTLMFTATWPESVRKLASEFLRDPVKLMIGENASGELRANERIVQEVEVVEEFDKQNRLFQLLKQYQSGKNKTDRILVFCLYKKEATRIEEFIRRKGFPVAGIHGDLSQEKRMASLAEFKNGKVPCLVATDVAARGLDIPAVKVVINVTFPLTVEDYVHRIGRTGRAGQDGRAITLFTQNEKGLAGALINVLKKANQPVPEELMKFGTTVKKKGHDAYGAFYKDTGDAKQATKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGW5</accession>
    <name>A0A9Q8PGW5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposon Tf2-6 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766790.1">
        <property type="nucleotide sequence ID" value="XM_047908363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGW5"/>
    <dbReference type="GeneID" id="71989093"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09215"/>
    <dbReference type="OMA" id="TANQDAN"/>
    <dbReference type="OrthoDB" id="3946086at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="39"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="32371" checksum="08BE31A78A4ABA74" modified="2023-09-13" version="1">MYFKDLRKRLQEYIDHCPVCAENQTLRHKPFGFLNPIDVPEMPMAVQTADWIVKLPPTSEGFDALLTVTCKKSKRILLVPGRETWTAEEWADAYLTSLRKCSWMIPMALVCDRDPKWLSAFFRRLFGCLNARLLAATAHHPQTDGQSERTNQTVEIAMRYFVTANQDANWTDVLPDLQSFLNSSKNATTGVSPDQYLFGFDLNTDALIGLRQLPDEDFRALRLQYREQADEALDFANVRMKDRYDDKHERKTFDVGDYVYLRLYHGYKVHGEKSRKFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGY9</accession>
    <name>A0A9Q8PGY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766677.1">
        <property type="nucleotide sequence ID" value="XM_047908352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGY9"/>
    <dbReference type="GeneID" id="71989082"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09204"/>
    <dbReference type="OrthoDB" id="10508946at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040321996" evidence="2">
        <location>
            <begin position="18"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="18883" checksum="050806F2B092598E" modified="2023-09-13" version="1">MQYRNLLLLGLVSVAIAQNDSDCDSPDSNTDNGGNNCSTRQNNDNDNDSAATSTLNGIVVTSRDTTTDVGQSTTLVPVLTQSVATTTDVGVDTTRETLTETTDVGTTPTKTVVQFATTTDVNLQSGYAYTTDSSGKTIATFTGTGTAPSFTGIVPGDVTSTDSGVMATAVPYVGAAAMAGLAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH11</accession>
    <name>A0A9Q8PH11_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS-type transporter oryC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08970</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766598.1">
        <property type="nucleotide sequence ID" value="XM_047908118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH11"/>
    <dbReference type="GeneID" id="71988848"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08970"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="131"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="625" mass="69553" checksum="EA8B49CE7D176ED3" modified="2023-09-13" version="1">MATAAAHKVQGITELLEMVLYELPPIDILVYQRVCQRWKDIITHGEKFQQALFFKPATNGTLKPRKERTFRELASSVEATWADASKPQRIFLNPMLAELIDAVKNGRDKKWTSQNASWRRMLLTRPSSDETCVMATDLDFLQGYDQGVMNGLLTLPTFYNQFPSINTSTPELDSKNATLQGTAVALYEVGAAFGALACFFLGDRFGRKWTTSGGAAVVLIGVILQTTSFQLAQLIVARIVTGLGVGSFTANIPTWVGESSDAHQRGGLIMIEGSAAIFGVMFVGWLEFGFYFIRQNEVAWRFPIAFQAILPIIVMIMVPMLEESPRWLVSKDRHQEAAQVLSKLEDAPADSPAVTSRLQSIRASIELDGQGHSSHPFARTPNRHLNRTLIAIAVNILAQMSGVNVITFYSNTIFQRDLGYSPVLSRIITSCMQTWQFLMATLAVFLIDRFGRRKLLITGAFLMCVANAGLTGLRSHADNATAAGCSLIFYFLALAAFPIGLFLIPFMYSSEIAPLRIRSQVTAMSGFSNWMFNFLVAEVTPVAFESIQWKYYLVYVCTNLVSVVTFYLFLPETMDRTLEDVDAFFLGSRNMLQPVKIAKSMPAGVAGEWDLREKVAEEDEKVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH27</accession>
    <name>A0A9Q8PH27_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MATE efflux family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766761.1">
        <property type="nucleotide sequence ID" value="XM_047908301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH27"/>
    <dbReference type="GeneID" id="71989031"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09153"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="52149" checksum="B3BD9646E9181C3E" modified="2023-09-13" version="1">MSLATHPESAAGSEETLSNIKAITFKDETWILLRYSGPLALTYLLQYVYQIVVILVASRLSTDELAGVSLGTTTSNILGYAVFEGMATALDTLCSQAYGAGRMTDVGMHTVRFTIFLHIVAIPIALLWLFAEHILILVKVPSKPLIENAGSFLRFSLIGVPGYASFEAGKRFMQAQGNFAAGFYVLLACLPINIALTWALVVPAGMRVAGAALATSLTNCLRPILLIAYAIFVNRSTLKCWPSTKEIRGYWNHEWKSMIWLAIPGALMTLSEWLQFEILTCTSYLGTAALAAQTFLSTTAVLVWHIPFSASIASSTRIGQLIGAGFTSSMTKLMRWHALVFGLISVLCFGLTIGIMALIQRFLIHDDEVAEIIRITLPFVAILVVFDATQNWPHGVVRGFGWQSIGAWVTFVLGYLYATPLAIYLELGPPHLGIRGLWIGLGSGLLAVTVIETMVILWKLKKTDDLRIEDHTAGNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH79</accession>
    <name>A0A9Q8PH79_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chermesin D/asnovolin J monooxidase nvfH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766827.1">
        <property type="nucleotide sequence ID" value="XM_047911131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH79"/>
    <dbReference type="GeneID" id="71991861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11983"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF2">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE AUSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1107" mass="122075" checksum="A915122AF4C44965" modified="2023-09-13" version="1">MAATAVQTNGVNIPAPDLNGAQIADSIDFTTKYEAERDKRLGKGLGQYVELSKSKEFGRLLEDPWVEAGTPVPEILPDGGHTKFLIIGTGYGGILLAVHLIKSGFSSSDIVFVDPAGGFGGTWYWNRYPGLMCDIEAYVYMPMLEEMDYMPKHKYAAGEELRHYANKIVEKYGLQDAAMFQSETKNMDWDAAKQVWQVEIEQMPKGGQRSNINVTADFVMLANGVLNNAKLPNTLGGDTFRGDMFHTARWNYGVTGGSPAKPELTKLKDKRVGIIGTGATAVQIVPQLAKWAKHLTVFQRTASAVNVRGNRETNVATWKTEVASHPGWQKERNMNFFKFVGNTDPKPKVDMVSDGWTGMPSFSALIGSPAYDVGVQNVGDHVARMHALDFPHSEKVRRRAMQVVKDEKTAKDLQAWYPGWCKRPCFHDEYLQAFNQPNVKLVHTDGKGVDRVTPNGVQFNGIDYDVDVLIWATGFSGAGIGTVASRASVNLTGSGGQTMDEKFAEQGFSTLHGVVSRSFPNFFWQGIQQAAASPNQTFLLEALSKHISYIIATASKKSGSRPIIQPSLDGEEEWSSRIVAGAATFASIAGCTPSYMNNEGESRGMSIGEQMKAARGSVWSKGIADFVDVIEAWQAEDKLAGLEVKSAALVSSPDEGSSTRARRIGNSSAQGTVIFHSKGQLEVSSQSKSPKQKDDRNIAADREAFLKAVADAIPRQSLWCDWLRSASTERLRFQSTFLSIFFPTDNARFPGFDFILRSAPSSPTLQYALDALCLVHVGTASRDRRLQEAARRSYGMALSKMRKELMAQSRDPSKLMGAMHLLAICEFFSRIAASDGEGVMRHVRGMTQMLAACRPETLHPEIRILLGTQLRGLAVWDCMLRRKAMTGLGSLEHAMAMGTKFGATTELAKVAIRVPAILEECDILRAQGENTSINTVTTCLSKITALKDDLRACLDVWYSDTNEMPYRVAPVSELSNPRMIGADIDRLFPHAFVFPNSLGAPKHRSYWVLLLALTQARLELLETFPSLQGPYECDELERTAQETADNLCMTVAFDTQPSSGYVAMFSAMHPVQMASLWYRKKNDVRKLEWCRRALRSFQAAGLRPPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHU0</accession>
    <name>A0A9Q8PHU0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ISWI chromatin-remodeling complex ATPase ISW2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_11913</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767053.1">
        <property type="nucleotide sequence ID" value="XM_047911061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHU0"/>
    <dbReference type="GeneID" id="71991791"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11913"/>
    <dbReference type="OMA" id="VHDYQFF"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031010">
        <property type="term" value="C:ISWI-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000036">
        <property type="entry name" value="Chromatin remodelling complex ATPase chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000022">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000234">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.30:FF:000003">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="184"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="480"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="847"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="112"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1018"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1019"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1070"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO22687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1098" mass="125453" checksum="D77AD8F331DC679F" modified="2023-09-13" version="1">MNGDSAPGVGDGSMPDQMMVDTPDYTDSESNPTGANSVAGDIADGRKKRWEGNALRKSMFGKKHDRLGDSKEDDSIKRFRYLLGLTDLFRHFIDTNPDPKIRDIMAEIDRQDAEDEKAAQAGNKRKGGADGGRRRRTEKEEDAELLRQGKQEGKAEHTVFRESPSYIQGGEMRDYQVAGLNWLISLHENGISGILADEMGLGKTLQTISFLGYLRFVQDITGPHLVVVPKSTLDNWKREFAKWIPEITILVLQGAKEERHELINDRLIDEKFDVCITSYEMILREKSHLKKFAWEYIIIDEAHRIKNEESSLAQIIRVFNSRNRLLITGTPLQNNLHELWALLNFLLPDVFGDSEAFDQWFNNQDADQDAVVQQLHRVLRPFLLRRVKSDVEKSLLPKKEINLYVGMSEMQIKWYKNILEKDIDAVNGAAGKKESKTRLLNIVMQLRKCCNHPYLFDGAEPGPPYTTDEHLVDNAAKMVMLDKLLKRLKADGSRVLIFSQMSRVLDILEDYSVFRGYQYCRIDGSTAHEDRIAAIDDYNKENSEKFLFLLTTRAGGLGINLTSADIVVLFDSDWNPQADLQAMDRAHRIGQTKQVKVFRFITEHAIEEKVLERAAQKLRLDQLVIQQGRAQQQAKQAASKDELLGMIQHGAETIFENKDGFGAFGKGGQGDEDELEEILRKGEERTKEMNTKYEKLGLDDLQKFTSEAGTYEWNGENFINRKKEIGLNWINPSKRERKEQSYSMDKYYRNALMTGGPRPEPKPKVPRAPKQMAMHDYQFFSPRLGDLQDKETAYFRKENGIKAPLADGDEDTLDQRLQDQELEQSVIDKAEPLTEEEIAEKDQLAEDGFGDWNKRDFQQFVNGSAKYGRHDYDAIALEVDSKDPKEVKEYAKVFWKRHKEIANWEKHIAAIKEGEQRAQRVIEQREMLKKKLAMYRVPLQQLKLNYTVSTTNKKVYTEEEDRFLLVMLNKYGIDTEGLYEKLRDEIRESPLFRFDWFFLSRTPQELGRRCQTLITTVTREMEGGKENKRAAEEDEDEEDAPAPKKGKTARTSLGLGSAKNKAVNGAKGTPNGTSRAASVDTTASGGASKAKGRAPRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHW4</accession>
    <name>A0A9Q8PHW4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767315.1">
        <property type="nucleotide sequence ID" value="XM_047911549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHW4"/>
    <dbReference type="GeneID" id="71992279"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12401"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="78" mass="8263" checksum="C4F9F67E8EB2CD61" modified="2023-09-13" version="1">MTTNSSALYLSNSTCYFGAGQLAFPAFIPCGNAATNGHHACCYSNDFCLSSNTCWDNTTVVTYIAGCTDPLFRASTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PII7</accession>
    <name>A0A9Q8PII7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767423.1">
        <property type="nucleotide sequence ID" value="XM_047911656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PII7"/>
    <dbReference type="GeneID" id="71992386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12508"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF5">
        <property type="entry name" value="GENERAL AMIDASE-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="87"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="59021" checksum="7398875EBEC93109" modified="2023-09-13" version="1">MSDHKDNSWQAKAAAKRAAELAKIPHAWRLSAQYLKSDETSSDNVLDIPAKCGILTPEELQITQNFDAVSLAKVVSNGPLRSEDVAIAFCKRASIAQQLLNCLTETLFDDAIARGKWLDQYLVDHGRPVGPLHGVPVSIKDCFHYTGVQSTLGFVSYLDQPKPATNSYLVDVLLELGAILYCKTNIPLTMMTADSHNNVFGRTLNPHRLNLGAGGSSGGEGALVAIRGSVIGIGTDMVAVSVFQRFAMGLTGSSQRRVAYHWEMEPACAGPLANSFEDLELLTRSVIDAKPWNKDSSAIAYPWRADAASTQPTKLRVGYFVEDAEFPIHPPVRRALEATAKALAAAGHEIIPLNNIPSLREAGEIATDYWSLDNTKVWLQNIQAGSEPIIPSLQRHVWTIAKEKEGGYTLDDVFDINTAAGAYKDQWHALWSANKLDVILCPGAQTTAVPHDTYGMPWYTVVWNLLQPGVIIPAGKADKAIDKDDLAVEDPNRPYRAEDVHGAPTSIQLVTRPFEDEELISAARVIDQCLKIADRRVSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJJ2</accession>
    <name>A0A9Q8PJJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 6B homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13302</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768072.1">
        <property type="nucleotide sequence ID" value="XM_047912450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJJ2"/>
    <dbReference type="GeneID" id="71993180"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13302"/>
    <dbReference type="OMA" id="QDIGGMD"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000020">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000049">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000033">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 14" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="197"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO23706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="46926" checksum="361DD45C62EFF0FA" modified="2023-09-13" version="1">MADVLNPANTEAPHLKRAIPSSAIANVDTIEGLADGDDQYATYKKLQRQLEYIKLQEEYIKDEQRSLKRELVRAQEEIKRIQSVPLVIGQFMEAIDQNTGIVQSSTGSNYVVRILSTLDRELLKPSSSVALHRHSNSLVDILPPEADSSIAMLGADEKPDVTYADVGGLDMQKQEIREAVELPLTQFDLYKQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTTASFIRVVGSEFVQKYLGEGPRMVRDVFRMARENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTSNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFSTIASKMSLSPEVDLDSLIVRNDPLSGAIIAAVMQEAGLRAVRKNRYNIIQQDLEDAYTSQVKGTSEADKFDFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJJ9</accession>
    <name>A0A9Q8PJJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nonribosomal peptide synthetase TES</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768004.1">
        <property type="nucleotide sequence ID" value="XM_047912043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71992773"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12895"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000084">
        <property type="entry name" value="Enniatin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1223"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2327"/>
            <end position="2400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2854" mass="314308" checksum="EDD9E15C0A8F948D" modified="2023-09-13" version="1">MALAFGNMENSSLVVKDHRAPHDGRTKDSLLGRIREEAPPDHCNTQSFGRHDFKVERSLCQRLQVSSALHEYDLKTVLFAAFRAALYRTTGASDLTVGILSNVTSAPGNIGHDDVHDTQLHSISTKIEDNTRFVDLLQQAKGRLDQARDLDLGISAEATLSQSTLRHADSRIIFALRERPIEPDSHITKLYPSSDIIGSDIIWHFWLDEEGGSGNVYFANRAIDRDSIISLVSVFLGVLESGSDDPTTSCAQLLLLSNFSSIVPDPSRAVPKQHTSVCDAFREQVTRHPNTIAVKDSSQTLTYSELDTLSQKISNWLARRRCAAETMIGVLAGRSVVAVTTYIGILGANHAYVPLDIRSPVERLNHMLSSMGNQPLVLYGPGLESLAARMADAEYVSIAQILDDNVPVTPVEHMLPLPATLAAVIFTSGSTGRPKGVMIEHRAIVRVAKQESYQITPHSAEETSVVAHLLNPAFDAAMMEIYTALLNGHTLYCVDESILLDSHSLSEAFVRQSVKMAVFTPALLDHCLREAPVLFKQLKILVVGGDRFKASHARQLKRLVQGEVFNGYGPTENTVVSTLYRIPADDEHISDDVPIGQAVTGSFAIVADTKQRMVPVPPGVIGELIVGGDGLARGYLDTQLNVDRFVQISINGTAVRAYRTGDLARLRPSDMQLQFMGRIDHQVKIRGHRVEVDEIDRVLMSHSAIDSATTILYIPDNAEELDLVSFVTKSPGSRYADLGLDLAISNLGRDFVGWTSMYDGTLIPRHEMEEWLEDTIRTIQESCPGGALGKVLEVGTGSGMMLFNLTPMSTQYVGLEPSLDAVNFVNSAIESIADIKGKARVHQGTASGIGRWMDDCQPDLVVINSVSMYFPSAAYIYKIIEDCIGQLRPYQKTRLFFGDVRSYALYHEFLTHKACHNAVAEMTIGDLCAIVDEQMSREKEMLIDPGLFTALPVKFSGSIEHVEILPKRMHATNELSCFRYAAVVHMCGAAASPSQVHELAPDEWMDVSVERLDRAAIEKQLMVKSRSSSSSDIVLALSSIPYSKIAADKAIVDAIRVPGALGQQVEDLTKRFHEHTDAPLSWDAAGLHQLAKAAGLEVQVSWARQYSQRGGMDAVFFQPRGEMHCRRALKFPVDHDNRDPRTLCNQPIQVDGRIALQQELEVWARDKLPPYMMPRAVLVIDQMPLTNNGKVDHKKLAKMAASEFAAAIKRDSARNPPTRSVDSSIETKLKELWAMVLDVPVASIAADDHFVRKGGDSIKAMRLAAAARRHGLTLKIPGILTSPRLRDMARTVHEEAVEQQFSVQPATHIDVAPFEMLQYTSEAEARSSAMTQCDISAHSIEDIFPCTPLQAGLVALNLANPSDYIGRHVKQLLPTTGIERFQVAFGDVVRAHPILRSRIIYLPGDNFVQVVTKSQISWSLGTSVEEYTKKDRQNHMGLGQPLVRAAVITEGTQRYFILTAHHSLFDGWSMRILFDALDRAYHSLPISPPPPFQNFIKALVQHNQSEAGKQAWRANLMDNEAEQFPRLPNPGYRPKSDSLHHCRFQDMSWGEMDVTAAVAVRAALAILISQRENVQDVVFGTALAGRDSIPVAGIEEMTGPTLTTLLTRVTFACSQETVGDFLVRLQNDWAALSRYEHMGLAAIRDLSEDAHRATEFQTLLVVQPSKESLKHGENGHSLFKHEASVRAADNDLGAISTYAMVMECQLSKNGVDIRVTFDSAVVPEAQMRQMLSQYETILRKLCLPEAREQRLSEIEWLGEIDMSAIWKCNAKMPEAIESATHDLLSSTIRQRPSAQAIAAWDGDLTYEELDGLSTRLADHLLDHGVVDAVAVAIYIEKSKWTAVAMLAVMKAGGTSCLLDPSLPVARLQSMVDQLGPRIILASPRQRVSAQALFKELIVVVDAANATQWSSATSGRALPSVDPATPLYVVFTSGSTGAPKGVVISHGSFSSAIVHQHPRRSVGEDSRVYDFSSLAFDGSWFNLLHTLYAGGCVCIPSDTDRQNDLSGSILRLGATFAFLTPTVASTLDIAALRALESLEIGGEAADEDEMQRIQVHTSVRFIYGPSECTPITTMTKPGAHALSIGRPAGVLAWLVDPQHTERLVGVGCIAELWLEGPLVGTGYYKDPNRTAASFVENPPWLLRDRPGRPGRKGRAYRTGDLVRYQPDGSLTFVGRNNMQQVKVRGQRVELLDVQHNVQDVLKKSLPEVSVIADVCGPKKDTLVAFVHVQNKSWAALSFNEQTSLLREKAGNAKNELAGMVPKYMIPALFVPLESFPLSPTGKLDRRRLQAMPNELTQEQRNACSLLPSHDALAADQSRSCTEEEVRSPCTEEKLRSLWAMALNIDAESITTEDNFFHRGGDSLLAMKLVNAARRAGVSLSVADVWTWPQLSSLAAHVGICSSTNTSPGRMVEPATAATVDHDAHFSMTLPSETLPSNKPPSSETLPVTWSQYQFLNGTVNGYSAHVYHLLVDIPAGCDKEQVKNACSRLLHDFDVLRVRFVCSPYRVHQVFDDYQENQLPWQELQANDLDTLDTINRFCEADRATLGARPHPQTATTRFVLMHRQQRPHKLVMRLCHAQYDGVSIPRMLSTLTRLLHSGTAPAPPRSFADYLRYVLAQSPESYPYWRKLLQGTKAPTVIPSTKHRASVGVHLIRVSHTIPQPTIVASSAQTPAVRFLASCAAMLAQTTATRDVVFGCIISGRSSVPEDLQDVCGPCLNEIPVRVTFSDCSLAAITPQSAFEVLRQQMLESSAHDAVGFDEIAAHCTCWGEEVDDFGLTAHYQNSANLDLGVNVAKEISCVQHEDDLPVPKANYIEVEAVPLPDKTVRMSIMGKSSHYDERFLARLLHMVCGNYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJK1</accession>
    <name>A0A9Q8PJK1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase lcsI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12967</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767977.1">
        <property type="nucleotide sequence ID" value="XM_047912115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJK1"/>
    <dbReference type="GeneID" id="71992845"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12967"/>
    <dbReference type="OMA" id="LIWEFDW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cyt_P450"/>
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        <property type="entry name" value="Cyt_P450_sf"/>
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        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
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        <property type="entry name" value="CYTOCHROME P450"/>
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        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
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        <property type="entry name" value="Cytochrome P450"/>
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    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="206"/>
            <end position="233"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23611.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="37818" checksum="0322A76E18E9B857" modified="2023-09-13" version="1">MPKDPAWYPTPDRPPSLILANDYQHSRLRKLFAPAFSDRALAEQEPILQLYADLFIDGLKEQWRQSKAADMTKFDVISDIVFGEPFGCLRNHENHKHVDMLIKRLHGSPFFYAMLYYPITKLFKRYLFDNSLLQARKDYAKWVDEQVTARYGVLSHKELVTNVMAAGSEISSTTLTVAKYLLSQHPNVLKKLQDEVRQRWPSYDEITSSSDTRAPVGFQRRVGRGGGKISGHHIPEGTAVSVSHYGAYRSGTNFAAPDEYIPERWMDDSRFVKDKRDVFQPFSHGPRDCARKNLANVELDPRSKGWFDKLDVRNVWTKPELLIKLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK05</accession>
    <name>A0A9Q8PK05_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12938</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047912086.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_12938"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
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        <property type="component" value="Chromosome 11"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="entry name" value="MAP kinase kinase kinase mkh1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1652"/>
            <end position="1938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="1"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        <location>
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        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
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            <position position="1681"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
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            <dbReference type="EMBL" id="UJO23827.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1959" mass="212713" checksum="FB1AD755B2F200E2" modified="2023-09-13" version="1">MISGRHRSSSNRSTPDESHRSTPAHLRGAHQLVVPGNGNGRLVLHDIPATNTLTAHATSLLRPQGASDSPDPSIASIPPPSTSPRPRAHTYADPSMNQGRATPSTPGTTMQQSQWAAPGARHVSESQRAGQGYIPPPPPPQQPQPQAGMAFPPPPPRMPMSATQQHAPFVPPPPGQPNTYWNRAHQAAYPPPPPQTQPREPRAYDPSLYFEYANLPPLNDNAPLTSATYIPDGGSFGPGVGIPPLHTPSAMPSRPAAHSTHQSYYRGQSQDFTSTNDVWQHYGNEPTFRQQDTGAWYNHNQSHNHSNIQFQQQPPLQSQSVPPQLNTMPPPTPTAGRQKTLILPAKETEQHTSPADASRGAFSQHLAQNNDSASNRDHSSSGDTPASPHDHNWPAERVQIWLAAHAFSKEWQSAFQQLNVHGTQFLDIGGRDRNRNIGFVPQTLLPQVARMCTANGVVWDQNREREEGRRLRKLVRDVVKNGGAATPSTAATSSTTSLPLHNTTRRDSNQCTKSAGTDAGGMESSPNLTRNDTFGSTPNTADGGDNSPGSGLPIPTHTKKVPGSRSVTLDSFTNSLNDTERAEYSRSALRNLNEMRKHASPSGSTGDLSATNQNFRASPQQSPGLISARPSSNAGHTRFPSGSSHYRGPSSDTNIQQHSNANAGRFYAGLSSNSENDVTKHAGEDSVSDRRNGHDGSRPPPTDSSLRGSSRDTPASAKEHKGLWEKFRRNRKKDDHPSPDEEHGPVSPNLMRHPYGGKGGPATSDISLNERPALRKEQHLSVGSSDYVSALPRGRPQAREGDKKFIFVTPDGWNYRLIDITEVETADQLKTVICFNLGVPETPDLSIHITAPGKIEHEEGLTDDMLMNVRSKLASPTGDLKLFVRVPGDMPQPPESAGLGLSVLPTSPFSKATFGVNAMDEATRRRLQDQDTGSPSTIRSDGSTLVPEKAAQLLNLPKDGDSRQPEVQAIYQESMLQQDFQKLPYEQQQALLAARAEQHRRDTERKQQFYKAKRESMTLLDANGKRVHNFDSPRHAPYDLDRQFGSRPVSSESYNDERKADGFQPMRRPPPVPEPTSTLVKANSLTKKQGPTTRTSWNNRKEEPWKRISSGSLPEEEGKRPSSRGIGAALAGAGKAAGAIAAPNSAPAGGPPLVPSALQKSTTAPDLLAGDESHQRALAGINFNRSASGGRSSPGNGTPRSPFTTRSKGGQMFNVPAYNEDDEEDDEDTLKASQRPQLSIRLPSNPMLAKLQAQGRSHSPDLSPSSSHPPPSSSLNRMMSKRGPQFDVPEHEPDFAPSPNIGAFDSEDDDSDDGLFAIPLAKQKEEKKVPETPSQRKAKKILGVTGTESPRRSPNRPELKISTTRPNVNVKFESPKNPPLDKLTGGGLTDMELMGASAPFDPQSASSPGMTDSPDWPAPFGVNRRDSFAGEFRPPVEDIAERLDNFFPNVDLDQPMGEGEEGAENSPLTSDKSTDKSTLKSQPSSSELSVNISRTTTPASSVENMSILDSEGSTLKAGTVAERSMRKSGGLGRTKSIRDVVKNNYSHLGGPSHHPSLSSSTFSSRVPSTVGMPAPGLPVHTPLPNNRISTLKNDNAGIVRRKSTKMFGAKIEQVKPQRGSRLITNLDTIPQDTIPIGNVQHIKPERQPTFKWMRGQLIGKGTFGRVYLGMNTTTGELLAVKQVEVNPKAANTDPAKIREMVKALDLEIDTMQHLDHVNIVQYLGCERKEYSISIFLEYISGGSVGSCLRKHGRFEEPVVSSLTRQTLCGLAYLHSEGILHRDLKADNILLDLDGTCKISDFGISKRSANPYNNDITNSMQGSVFWMAPEVIRAQSQTLTAASTDGSLDVTSSAGYSAKVDIWSLGCVVLEMFAGRRPWSKEEAIGAIYKLGSLNQAPPIPDDVSTVVGPAALSFMYDCFTIDPGERPTADTLLRAPFCIFDPHYNFLDTELYAKIRGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKN2</accession>
    <name>A0A9Q8PKN2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrolase M10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-lactamase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768642.1">
        <property type="nucleotide sequence ID" value="XM_047912571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKN2"/>
    <dbReference type="GeneID" id="71993301"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13423"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF95">
        <property type="entry name" value="BETA-LACTAMASE-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="92"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="421"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="566" mass="63045" checksum="70E40B7BD8409D00" modified="2023-09-13" version="1">MKLSKYLIYLPPLLPAATCQCFDPSPSFPIPSWGTGGSSLASTLQIIEHEIHQIVAKEAYKASSFSLELTSASSTIWSLHHTARHRNETRPGTESVDENSVYRISAVTKVFTILGLLRQHDAETLNMEDPISKYVPELGGDIQWENITLRSLASHLSGIPREFAHSDMINQFQDPVAMGLPPGTKEGCPTCDEYNDYKPCARRDLLDAVNKLKPVFAPNEKGTYSNVGAELIALALENVTGMDLVTYLREAVLEPLGMKATSMDAPADDENAVLPIWSKGDNYWGIDTGVQNATAGLYTTSADMGKFMRYVLRNANQITRGVNWFMPASWSTGFRTFYGMPWEILRTEKVLKERQRPVTFVSKSGGMPGYYSRVTFMPEYGLGLTILVGGETGLLSELLELITTRLIREADPILWGELSGLYDGTYEAVEDGLKSSLTISSAPVGGMRVTSFISNGTDALHQVFGREASTERWHAQLVPTMLSKDEAKKRGDIWRLIIVPERLDQTDLVWDDLCGTDVDTGRYAGVPANEFVFWHDEGVVELPAWKVKLKRERQEKMVVQPWKVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKY8</accession>
    <name>A0A9Q8PKY8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyruvate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_14041</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768701.1">
        <property type="nucleotide sequence ID" value="XM_047913189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKY8"/>
    <dbReference type="GeneID" id="71993919"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14041"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF30">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE ISOZYME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="12">
        <location>
            <begin position="7"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="11">
        <location>
            <begin position="334"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>2</label>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO24335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="493" mass="54435" checksum="FB04981327876893" modified="2023-09-13" version="1">MADNTITLAEYLFVRLSQPGCRALHGLPGDFNLTLLDYVESSGLKWVGNANELNAGYATDAYARIHGIGAMCTTFGLGELSAVNAIAGSYAERVPVVHIVGTPGRPSQRNGMLLHHTITIAQADLIDPTTAPFEIDRVLRTCYIDSQPVCIQLPTDMVAESIGAEPLKTPIDVSPHPSNTEAEKLALQIVLDKLYAAKRPAFLIDGALESSDLIITIGTIQSDLNTTGFTYQISKLNTIDIEYDCVQVGYAKFDKVYFKSFVPPMEQQLDPARLAQTAYSIPKISLHTPVDTESQLITHAYLWPRVSKFLKLGDFVICDAGTSFVSVWDAVLPRNVQVINQILWSSIGYGVGAAQGASLAARELGKGQRIIVFEGDGSFQLTAQELSTIIHHDLDVTMFVIENDGYEIERWLHGWEASYNDIPQWQYSKLPEVLTTPDSPHKVRTWRIKTRSELEALLNDSTFAEGKGLQLVEMHMPRGDAPKTLRDFAARRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLJ5</accession>
    <name>A0A9Q8PLJ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769013.1">
        <property type="nucleotide sequence ID" value="XM_047912599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLJ5"/>
    <dbReference type="GeneID" id="71993329"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13451"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18652" checksum="C964CB16C67D1CC5" modified="2023-09-13" version="1">MSTTASPSSKKCHIISIPPELRLEIYEHYFKDFELDFSNRPSPEHAGKSVSQCPLLHTCALFRTEALAPYKKYLEACNKAANVALFSFREQTLEQARGADQGDRARYELGFRDACDRVNKKRHEWNAAHMAHARELCRVDWIDFMAVQAGWVRSRGSEEVASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ14</accession>
    <name>A0A9Q8UQ14_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_07119</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762960.1">
        <property type="nucleotide sequence ID" value="XM_047906267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQ14"/>
    <dbReference type="GeneID" id="71986997"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07119"/>
    <dbReference type="OrthoDB" id="5378633at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="15">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="16">
        <location>
            <begin position="133"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO18594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="55064" checksum="FD0CE54127DDD7D5" modified="2023-09-13" version="1">MPTSLALSTEACPGPESLASGCYESAPCRRASLPDCHLKQLVTCAADVLPTYSCKPTNICFCTNDDLAASLKACLVKSCQTQDQLKAQKFRADTCGLPVRDKSSVVRGLVWSLFAIATFFTIARLLSRWPRLNGAGYHWDDWTLFALYPLAIVLLYADFLFWFYVCQPLYMVVIFLSKISLLLLYLRTWPGDRFAPFRITNWAMIGAISAAMIAFVIASIFQCTPIRVAWSIAAPLAVEMCTDRVAQVLAAAGLNIVFDVVVIALPFPKLIRLDISWPRKIGLLFTFSIGSLVTICSIIRITYMSKFGESENPTWDYTYIGIWFIVEVYCSIACACMPATAGLVERCISKFVRRDATEPDFETNLSSMSRSKSPFDPEMQRSIRLGATSPGSQSMSDYIERRDKVLRVRENRIISLSGELSTIKTMQALHRRETEVSSEVLKGGSGSTVYAGPNNGIKLEVSHWSVADPIVARLGYQDRFGNARRIELLGRATPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URS3</accession>
    <name>A0A9Q8URS3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbonyl reductase [NADPH] 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764401.1">
        <property type="nucleotide sequence ID" value="XM_047909249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URS3"/>
    <dbReference type="GeneID" id="71989979"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10101"/>
    <dbReference type="OMA" id="GAQTPVM"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="291" mass="31599" checksum="31748DBA006BE066" modified="2023-09-13" version="1">MAVQSRIAAVTGANKGVGLAIVRQLALQYPTSPLNSGPFLIYLTARSPERGQEALNTLTSDPQFKDAGVLSQHGGDTTIKYHAVDIDQTKSVQDFRDFLQKEHSDGIDILINNAGIAMEGFDAGVVKKTLQTNYFGTLEICQSLLPLIREGGRLVNVSSMSGKLNKYSDEIREAFLAAAKKDVPAVTAIMQQFQKAVEAGQEKEEGFPSIAYGVSKAGETAYTKALALEGSWRKKNILINACCPGYVNTDMTKGRGRKTPDQGAQTPVMLALQDIGGKTGEFWQHEEVIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US96</accession>
    <name>A0A9Q8US96_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11517</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764912.1">
        <property type="nucleotide sequence ID" value="XM_047910665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US96"/>
    <dbReference type="GeneID" id="71991395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11517"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="16593" checksum="DF5D7C790D925D77" modified="2023-09-13" version="1">MARYRPSNAELLRSDVPHRTQPTPASTHSYRIPPSTMASGGKGKTGVGIGAGGKGLGQGGKTPKRHRKILRDNIQGVTKGDIRRLARRGGVKRISGQIYDETRSVLRIRLTDILKDICAVVESCGRKTVCVTDVVFVLNRLGRPIYGFGEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USJ6</accession>
    <name>A0A9Q8USJ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765212.1">
        <property type="nucleotide sequence ID" value="XM_047910169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USJ6"/>
    <dbReference type="GeneID" id="71990899"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11021"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="31"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="574" mass="63477" checksum="5FD380F3984A9FAB" modified="2023-09-13" version="1">MKRSHSAMANSQEGPPPPPLQDVPTAKEKKYDRQLRLWGTAGQIALEETHILLINNGSGVTGVEALKNLVLPGIGHFTILDSGIVSEADLGVNFFLHDASLGKYRAEETVKLLQELNPDVKGHAITEPIETWASNQDALKPYTLIVVAAPIDPAILYNIQNASIGVPIFYIHSVGFYSQFSVSLPPDFPIVDTHPDPTATTDLRLLTPWQALSDFARQQTTNMDKMNGEEFAHIPYVCLLLHYLEEWKTTHAGKLPLEYKEKTEFRNLVRTGSPSEENFDEACAAVLKSLNPPTPERKVLEILNAPEAQQITVTSAPFWVIANAVSQFYQQHNELPLPGAVPDMKARSNTYIELQNIYKAKAREDANEVLKIVRQTEQRVGRSVAIDEKEVDNFCKGAAHIALVRGSPFKIAQAGKAISFGGRAKGLTNQLQDPESMIHLYLSFQAWDEFVAFHTTIAKEIGGEGLRIPGAGEAVDWEEHAFNLFELAMRLMDNIINQAGTRVESPRYDQVHEKIRKTCTELARAGGAELHNIASLSGGLIAQEVIKVITKQYVPINNTCVFDGITSKTGVFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USS6</accession>
    <name>A0A9Q8USS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765467.1">
        <property type="nucleotide sequence ID" value="XM_047910733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USS6"/>
    <dbReference type="GeneID" id="71991463"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11585"/>
    <dbReference type="OrthoDB" id="5413827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="21875" checksum="37DE3973E9FF054F" modified="2023-09-13" version="1">MGLLELPPELRNQIYQFALVDPNDQDFGKYQDHKPREPALLLTNRQIRNGAFPVFWGGNTFCFVNSIMTDLWLKRLQPHKLAALRSVLASHPDYAHIWSMQVSRGKEDLQKLGLRCKGLCEDVVKLPMRVKVEEVERGEEDQDEDEKMHDDEEESTEAQEQHEVIWIALPDIDSYEAADGFVVRKAIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USZ7</accession>
    <name>A0A9Q8USZ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910424.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71991154"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11276"/>
    <dbReference type="OMA" id="TCWILVD"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF4">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="173"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="43282" checksum="A13DB637D6E8B60F" modified="2023-09-13" version="1">MDSTGLPSKESPDLRLVVATYEELIQQQHANSEEWRGALSHEQYLQRESILYDQDLTRDGGLTPWALVYQPDSNGPRQVLCGCETLNKRALVALDGKVEDVICHGVASVFCPPKYRGKGYAGRMMEDLGKKLRSWQVDNGKACLFSILYSDIGKEFYTARGWHPFPSAQIILPAAAEQSSKDARPLGAEELSELCTADEGLLRKKLSALKDAGRTVVATVPDHRTLAWHHAREDYVAKQLCGKQPHVKGAIVGDEPGRRVFAYWTRVWTNPQEDGPNTLHILRIVVEEDTLSDIVPASTEVVAKVKDSRVTHALAAVLSVAQSEAAKWDMKEVSIWNPTSATLAAAQLTNPSVAIQHREKESITSLQWYGETGSWQDIDWVCNEKYGWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTK9</accession>
    <name>A0A9Q8UTK9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766263.1">
        <property type="nucleotide sequence ID" value="XM_047908858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTK9"/>
    <dbReference type="GeneID" id="71989588"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09710"/>
    <dbReference type="OMA" id="GMEYTES"/>
    <dbReference type="OrthoDB" id="3360856at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045702">
        <property type="entry name" value="DUF6060"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19535">
        <property type="entry name" value="DUF6060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364558" evidence="1">
        <location>
            <begin position="19"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="334" mass="34759" checksum="60DCF8222CE68033" modified="2023-09-13" version="1">MAPRTIALTAAMLGVAIASPVTSPYTFVERRQGTSCGGTDANGQIFVADVGFYSEMNCNDETGGVCIYTGQETIDAGAGNYGCNPGLLPEDAPFFLKVVDSPFSALQLLFTRDQSCPPSGPGAVYATLVDNASCVQSNLGGDAPGISVFPNGGSGLTRLSTPAREFPMTGVTRNTAANVERQALAAMKRQSNTECDGFVTDSQQPSQSRTVQVSNIIDCTNGGEQGCIISVEEQESKSISTSYSLTAGGGIEGIFSVEATFGMEFTQEVSTSVQNGFNVDAGQRGYIGAYNGATLFTGRYTGCNSGDAEQPGSVLALKDNQIFYSIILTGASKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU96</accession>
    <name>A0A9Q8UU96_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766923.1">
        <property type="nucleotide sequence ID" value="XM_047911356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU96"/>
    <dbReference type="GeneID" id="71992086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12208"/>
    <dbReference type="OrthoDB" id="4156595at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="20417" checksum="1C896B203C5EF5D1" modified="2023-09-13" version="1">MMAVTVEQTTADTTTAQAKSHRGRRQSRSKKSDPFLDLSDDALKLPEQPSPSSRDQNGPANVESLLADLVLTPLNVISFIVSLFVVERQQRQWRLSQHAPPQESSAWSQFGMQDPEPYQEARGTTWHPRLSWRRRKVAKAELANVFEMRGRVVVALVTWTFVGFVGIAYAARRMYQWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV78</accession>
    <name>A0A9Q8UV78_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Taurine hydroxylase-like protein SAT17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767986.1">
        <property type="nucleotide sequence ID" value="XM_047912355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV78"/>
    <dbReference type="GeneID" id="71993085"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13207"/>
    <dbReference type="OMA" id="GWKLPFW"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000009">
        <property type="entry name" value="Putative Taurine catabolism dioxygenase TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="4">
        <location>
            <begin position="93"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="396" mass="44935" checksum="F19FB2DD7E7FFF2E" modified="2023-09-13" version="1">MATLAQAPVEPPVFRYDQASKAVFPDGIKTSGQCPPTYEQLVPYSEFPKEITGPTVWKKEDYENHPERWVHRFNEDEVKELRKAADDFLASGTPMTGITKDKFPLPNMAGFLEPMRKEILNGKGFILFKGFPVQEWGNHKSAVAYMGLGTYLGYFVSQNGLGHVLGHVKDTGADPTQIDKVRIYRTTARQFFHADDCDIVGLLCVAKSLEGGESDIVSDHHVFNTLQRERPDVVETLTQPIWYFDRKGEVSAGQEPYTRQPVFYKETGKDGRLYTKWDPYYVKSLKRFSDTGAIPPLSEKQQEAAQVLEDTCLRLSLHMVLDIGDIQFLSNAHVLHSRTAYKDYPAPHPRRHLMRLWLATPEDEGGWRLPFADSRHKKRGGVQVNDTPPRAPIDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWR4</accession>
    <name>A0A9Q8UWR4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769649.1">
        <property type="nucleotide sequence ID" value="XM_047913515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWR4"/>
    <dbReference type="GeneID" id="71994245"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14367"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31944" checksum="9CF6D8DDF5D2FB39" modified="2023-09-13" version="1">MSTTTKKRSANGEEPGTKRLKSNYFSDNITTILVREEETSFTAHKNTLCKEGVVRLPEAQAETFAVYLHYAYTGHFDWSLIRTHRTGYKDSIPRNFHLWLLANYLQNSEVCNAIVDHILRFSERDSGRDTINNGWTADNLQSAWTLVPEGSNLRRLIIDLVIAHATPISFGKGCNKWPQDLLLAAAKKHFEGKAEKTVKPAGSRRTGRPAGWRHGHDRTSSGAEIPATSKVTDVDPITPTYANRCHHHEHEDGEERCDEVLGDSTSNNDEDGAGCVVIDIYPEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UX18</accession>
    <name>A0A9Q8UX18_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U3-containing 90S pre-ribosomal complex subunit-domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769758.1">
        <property type="nucleotide sequence ID" value="XM_047913495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UX18"/>
    <dbReference type="GeneID" id="71994225"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14347"/>
    <dbReference type="OMA" id="DHFAQKA"/>
    <dbReference type="OrthoDB" id="1929311at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032704">
        <property type="entry name" value="Cms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24030:SF0">
        <property type="entry name" value="PROTEIN CMSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14617">
        <property type="entry name" value="CMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30846" checksum="07DEF09E1497CB81" modified="2023-09-13" version="1">MSDSEDQAGVPLIEDLSDSPDPQASKSTKRKREADDESKKAARKKKRTKKKPDDVDHSNLDSELGINRALAHMDSQLMADHIAQRTRRFQPDLSAVELEDVHIPAKAILDTTSFEKPRTTDVLPDFLEQFAGSAKRKKKLSQSSTSKAFPHTLVITGAGLRAADLTRALRKFETKDSKVAKLFAKHIKLKEAIETVKKTKMGIGVGTPQRVIDLLEDGALKVEGLERVVVDASHIDQKKRGVLDMKEVQVPLVKLLGREELRGRYGKGEGKVEFLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-12-07" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>Q5VB04</accession>
    <name>Q5VB04_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">Avr4E</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Secreted 10.9 kDa elicitor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">avr4E</name>
        <name evidence="14" type="synonym">Avr4e</name>
        <name evidence="22" type="ORF">CLAFUR5_10278</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2004" name="Mol. Microbiol." volume="54" first="533" last="545">
            <title>Cladosporium fulvum circumvents the second functional resistance gene homologue at the Cf-4 locus (Hcr9-4E ) by secretion of a stable avr4E isoform.</title>
            <authorList>
                <person name="Westerink N."/>
                <person name="Brandwagt B.F."/>
                <person name="de Wit P.J."/>
                <person name="Joosten M.H."/>
            </authorList>
            <dbReference type="PubMed" id="15469522"/>
            <dbReference type="DOI" id="10.1111/j.1365-2958.2004.04288.x"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2012-11" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ALH</strain>
            <strain evidence="7">CH6</strain>
            <strain evidence="4">COA</strain>
            <strain evidence="5">ELH</strain>
            <strain evidence="6">EMP</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2014-11" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="De Wit P."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CHEAV</strain>
            <strain evidence="8">CK813</strain>
            <strain evidence="9">COM</strain>
            <strain evidence="13">EAV</strain>
            <strain evidence="10">ELS</strain>
            <strain evidence="11">EOP</strain>
        </source>
    </reference>
    <reference evidence="14" key="4">
        <citation type="submission" date="2018-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Lucentini C.G."/>
                <person name="Medina R."/>
                <person name="Franco M.E."/>
                <person name="Saparrat M.C."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CIDEFI322</strain>
            <strain evidence="15">CIDEFI323</strain>
            <strain evidence="16">CIDEFI325</strain>
            <strain evidence="17">CIDEFI326</strain>
            <strain evidence="18">CIDEFI327</strain>
            <strain evidence="19">CIDEFI329</strain>
            <strain evidence="20">CIDEFI330</strain>
            <strain evidence="21">CIDEFI332</strain>
        </source>
    </reference>
    <reference evidence="22" key="5">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="6">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AY546102">
        <property type="protein sequence ID" value="AAT28197.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132832">
        <property type="protein sequence ID" value="AGD98914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132833">
        <property type="protein sequence ID" value="AGD98915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132834">
        <property type="protein sequence ID" value="AGD98916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132835">
        <property type="protein sequence ID" value="AGD98917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC166871">
        <property type="protein sequence ID" value="AGE81873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234082">
        <property type="protein sequence ID" value="AKG51723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234083">
        <property type="protein sequence ID" value="AKG51724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234084">
        <property type="protein sequence ID" value="AKG51725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234085">
        <property type="protein sequence ID" value="AKG51726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234086">
        <property type="protein sequence ID" value="AKG51727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234087">
        <property type="protein sequence ID" value="AKG51728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308682">
        <property type="protein sequence ID" value="QDM02401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308683">
        <property type="protein sequence ID" value="QDM02402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308684">
        <property type="protein sequence ID" value="QDM02403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308685">
        <property type="protein sequence ID" value="QDM02404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308686">
        <property type="protein sequence ID" value="QDM02405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308687">
        <property type="protein sequence ID" value="QDM02406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308688">
        <property type="protein sequence ID" value="QDM02407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308689">
        <property type="protein sequence ID" value="QDM02408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q5VB04"/>
    <dbReference type="PHI-base" id="PHI:529"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007706690" evidence="1">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAT28197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AGD98914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AGD98915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AGD98916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AGD98917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AGE81873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AKG51723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AKG51724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AKG51725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AKG51726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AKG51727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AKG51728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDM02401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDM02402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDM02403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDM02404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QDM02405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QDM02406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QDM02407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QDM02408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO20373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13048" checksum="46399A290C30503E" modified="2004-12-07" version="1">MQFPTPHLLLTTLLATITTADFSRDCPPGSGVGNQAEWSARGVDGTAIPRELDAHSLCDCFKPFLNVLGCSVTSVVTERAVFVKGHLNYCARMSESVAGISPCKEWEIEVGGAHPERMANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4Z8</accession>
    <name>A0A9Q8L4Z8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translin-associated protein X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_02114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755253.1">
        <property type="nucleotide sequence ID" value="XM_047901262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4Z8"/>
    <dbReference type="GeneID" id="71981992"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02114"/>
    <dbReference type="OrthoDB" id="31005at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO10887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29740" checksum="BE029C4FB2FC4DDD" modified="2023-09-13" version="1">MGAKRSRADMEAKDTGSAHSPFMPMFEAFRAELDEHHDRRERIIKASRDITAASKKIIFTLQRVRKLNEPLPQHVVKGNKQYYDVIGERLASVSGDLRGLSAWRYARQISGGVQEYMEAASFEHYLTTASLLTYDDASAQLLARDKEGPGIELSAEDYLLGIFDMTGELMRFAITTMATGGALPGVTSENAGSTVSERNVLHDLRALRSALESLNAGQGPFAKEAEKKMDVMKTSVEKVERSLYGLVVRGAERPKGWLPDADRSIEVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5U2</accession>
    <name>A0A9Q8L5U2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_01212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Spindle pole body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755776.1">
        <property type="nucleotide sequence ID" value="XM_047900360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5U2"/>
    <dbReference type="GeneID" id="71981090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01212"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000012">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="11">
        <location>
            <begin position="87"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="12">
        <location>
            <begin position="288"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="514" mass="56968" checksum="AC2E9ECC0231EBB1" modified="2023-09-13" version="1">MCWTLEAKVVSAACPTIASRAPSAFPRIHADCGACQHSKMPREIITLQAGQCGNSVGSQFWRQLCLEHGINQDGNLEDFATEGGDRKDVFFYQSDDTRYIPRAILLDLEPRVINAIQTGPYKNIYNPENFYVHKEGTGAGNNWAAGYDMGGQVSDEVLDMINREADGSDSLEGFMLLHSIAGGTGSGLGSFLLERLNDQFPKKIIQTYSVFPDTQNAGDVVVQPYNSLLALRRLTQNADAVTVLDNGALSRIAADTLHVQEPSFEQTNQLVSTVMSAATMTLRYPGYMHNDLVGIVASLIPTPRCHFLQTSYTPFTGNNVEAAKTVRKTTVLDVMRRLLQPKNQMVSTKPSKNSCYISILNIIMGEADPSDVHKSLLRIRERNFASFIPWGPASIQVALSRCSPYLQPPYTTRAPPRVSGLMLANHTGIATLFKRIVFQYDRLRKRNAFVDTYKRYELFRDGLREFDTSREVVMDLINEYEEAERADYLSGGKTEDETNGGAASDARTDGATGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5Z7</accession>
    <name>A0A9Q8L5Z7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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            <authorList>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="Pkinase"/>
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    </dbReference>
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            <end position="851"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L758</accession>
    <name>A0A9Q8L758_PASFU</name>
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        <recommendedName>
            <fullName evidence="14">UEV-domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    </dbReference>
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        <property type="entry name" value="ESCRT_assembly_dom"/>
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        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
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        <property type="entry name" value="UEV_N"/>
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        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="11">
        <location>
            <begin position="6"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="10">
        <location>
            <begin position="496"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
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            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
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        <location>
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            <end position="262"/>
        </location>
    </feature>
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            <end position="284"/>
        </location>
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        <location>
            <begin position="317"/>
            <end position="354"/>
        </location>
    </feature>
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        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="62832" checksum="2B7D7067BEA11D12" modified="2023-09-13" version="1">MAQVSDKVLAWLYSVLHEYRDPQRTYSDAARSLSAYPSLQTRTETYTYESGASALLVILHGTLPVDFRGTTYRFPVKLWIPHAYPYDAPIVYVDPAKDMAVRPGQHVGVDGRVYHPYLRDWQSMWDRANVAEFLECLQQAFAKEPPVISRAQQQQYQRPMAQNQQQMPGASQTPPRLPPKPGGSNGGPVGTPGDNAPPPVPPKPGEEYAESSRNPLRDGPPLPPLPHEVAPRPHGNPASQPPSGQWQCLTPNQHLTPISSGHQNDRPPGPSQHILQQPTFQQRTNYDRSPVSPVSPVHGYSELPETKYSRPPPLPQPQAQQQMQVPSMSAPHLQQQHRPQQSFQQRQPQPSQPFNHQSQVQHQQAPRKQPAPDLLTDPFEVALPSSSRQSLPAPPIPPNPEREHLLHAITGTLVQQTQQKVAQNLAAIAPLQAQHSALRSAYERLEGELRQLEQLDQALASNEAILHQSIQECDRTIKTTKSKKQPPIDDVLIAPTMVANQLWTLCAEEAASREAMYVLQKAVDRGRVSGNDFVRQMRGLGRECFLKMALARKCARGMGLKMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7E6</accession>
    <name>A0A9Q8L7E6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756556.1">
        <property type="nucleotide sequence ID" value="XM_047899982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7E6"/>
    <dbReference type="GeneID" id="71980712"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00834"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="49456" checksum="AB1D3934AA6F810F" modified="2023-09-13" version="1">MAGISHIRSIDSPVNASVRIGDDVFINDGPMYGAATISVAGSLVLSGQWVLRQYQNNTTEQVLSLERNTIGPFSAPEKVAPEGAGDNEAEEIDTPAGSPKRKASTAVVEAATSRKKSKVSRASSRLEDRNQKMDEKAPIDQPEEEQGQAAPQDDPDGSSEALSDLDGMDADEKAYEESTRAEENPDEAQQEVQQDILQEPQQGLQPEVQQDVLQTPLPDLSNRPRRADPNTKPSYTAASRRPEVRSKNDGDHMGGLLFEKGPAIGTPKPRQRSSIPGEKPSDSELGDRLGNVIEIAGKQNSAKQRISSATGMDTGVKRRLLQGVSGPEGEERSDTGADQNDNQVFPQKDPQRKVRRRKVAAPELGNEDDLAAEDDELDATAPRKAAVKPSGDRPRKKSNVRVDSEDEIVGDEPSRLNAVPKPKKGKLAKQRMVGKKQKEAGSPGDYVANKSQKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8P6</accession>
    <name>A0A9Q8L8P6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757273.1">
        <property type="nucleotide sequence ID" value="XM_047901342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8P6"/>
    <dbReference type="GeneID" id="71982072"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02194"/>
    <dbReference type="OrthoDB" id="10260961at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103:SF2">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="46920" checksum="03BB654EE2BF6EA6" modified="2023-09-13" version="1">MVIKCQHATLKILACSNPRPGFHVNMEPLYSFTIPSIEDDTPLDCRIYHDTNSLSNRPGTQLLRGAVLAHPYPPLGGCYDDPVVLALTETLLADGYIIATFNFRGAGESAGRTSWTGNSEVLDYCSVVGLLFYYLQDIQGSSQNSEALTPIISATTTEPNAGYADPAKRPFEILLGGYSFGALILARLPPVSSIINRFEAAERGTAACEIILRARKLATQLQSIAQEVQSPIRGRNLIPSSPHSPHHMASPVTFGGEETDASDRRRSRDSRRSVDVVREVGHRMKPHLHRHSGNHSNDSTEHHRTTTASSTHSSGQNFTTAYLLVSPVLLPLTTTICPPGLPFPGLHNPFHGHSGSTSGLLSLQAPVHIIFGNQDGFTSVKKLQQWATKLCKEAPHAGRQEIAGAAHFWREEGAMRELQSSVATWVVTLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8R4</accession>
    <name>A0A9Q8L8R4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase BOA17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757233.1">
        <property type="nucleotide sequence ID" value="XM_047899664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8R4"/>
    <dbReference type="GeneID" id="71980394"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00516"/>
    <dbReference type="OMA" id="VWEAYNI"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="30411" checksum="F71B6C487E5E243B" modified="2023-09-13" version="1">MAPLVFFIGAASSGFGNGIAEEALSRGHKVIATARNASKIAHLKEKGAVTMNLDVTHSLDELKAAVADAHKVYGRIDILVNAAGYILEGAIEEASPKETLDSFNTNVFGVLNLTRAVLPYMRTQRSGTIAQFGSVGSWRGFAGGGLYVATKWAISGLTESLRLEVAPFGIDVVCIEPGYFRTGFLNLGARFFTEERIQDYDETTVGEVRRMLTSADNSQPGNPEKGCRVCVDVLTRDGGREVPVRLVLGSDATEAIRGKCEETLTLLGEWEGVSRSTDFEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9K8</accession>
    <name>A0A9Q8L9K8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757811.1">
        <property type="nucleotide sequence ID" value="XM_047902655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9K8"/>
    <dbReference type="GeneID" id="71983385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03507"/>
    <dbReference type="OMA" id="RIIPPGR"/>
    <dbReference type="OrthoDB" id="5411141at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="351" mass="38242" checksum="58665B06EFBE2C1D" modified="2023-09-13" version="1">MAANDSEPSSGFFTYTSSYAPLSTVSAATPTSSIPTTSTIPASGTAFTGQQPNDDYSSGLSSSAKKVVICTTTIGGTLILALLMFAMWRKRRGASYSEIVRFRPQSNPDMTGPCSLSESLTALPIYRSERFSVRSSRHLLAGAPKPPRKRASNGSSLAKDLCPQTPEPLVPSRPHTSRSGKALRPKGSRTFLNATPPRPSLNEPEKALTAHRPSEELPVMGHFIHSKTSYHNMKQERPSTAPNQHPNLHLEAPDAADRWSWTNSQAPPTPRIIPPGRLSFSARSIRSISSWVTAGSKKKDDEPKTPSPLRPKSKRQRSRQELLKNHAVQPILAPPLARNRLSKHQGGGIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Q5</accession>
    <name>A0A9Q8L9Q5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cercosporin MFS transporter CTB4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cercosporin toxin biosynthesis cluster protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00717</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin. The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules. These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids. Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757139.1">
        <property type="nucleotide sequence ID" value="XM_047899865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Q5"/>
    <dbReference type="GeneID" id="71980595"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00717"/>
    <dbReference type="OMA" id="WFESFAI"/>
    <dbReference type="OrthoDB" id="3357846at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015244">
        <property type="term" value="F:fluconazole transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="128"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="586" mass="64903" checksum="15826C2624FC0107" modified="2023-09-13" version="1">MSQLIRDTAFGHAVRFLSRGKLLRYQEEEDPSLYTKFIDQEKSGNLAHHGDTNPPDDDASEKENDDLDKPDRPTANGWSSSEASGTTGNDATVNEASGAKIDQEKGKDIHLVSWWGKNDPENPQNWSTFKKVFVTFEICLLTTSVYIGSSIYSAGTADVVAIFGVSQVAATLGLCLFVAGYGLGPMLWSPMSEIPQVGRNPIYLGTLVVFVALQPAVALASNFGMLLAFRFITGFFGSPVLATGGASLADIWSPAKRAYAMSIWGVAAICGPTLGPLIGGFAVQYGGTNGVIKAPWSWPIWELMWLSAFCLIFLFFFFPETSANNILLRRTRRLRKLTGNDKLKCEPELMSEQMTGRDVVMMALVKPFTLNFTEPMVFLLNLYIALIYGLLYIWFESFVIVFIEMYGFGLGTEGLAYLGILIGAFVVIPPFFWYLHKYLEPRFDENGELTPELRLIPSFFGAFCIPICLFWFGWSARPDIHWIMPIIGSAWFSVGAFLLFNSVLNYLPDAYPEHAASVLAGNDFMRSSFGAGFPLFASAMFNNLGVAWASSTLAFISIAFIPIPFALYKYGGTLRKNYSKHARKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAQ1</accession>
    <name>A0A9Q8LAQ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758334.1">
        <property type="nucleotide sequence ID" value="XM_047902537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAQ1"/>
    <dbReference type="GeneID" id="71983267"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03389"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="54" mass="6087" checksum="B0D63D425816C4CA" modified="2023-09-13" version="1">MAFATEYRRRMDMGLVSQFPALHKGSKRDALSARRRNHSLTDLQATATATTTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAT7</accession>
    <name>A0A9Q8LAT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758220.1">
        <property type="nucleotide sequence ID" value="XM_047902838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAT7"/>
    <dbReference type="GeneID" id="71983568"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03690"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37929" checksum="E229AA791EC5C15D" modified="2023-09-13" version="1">MAAPPAVPAPAAAAPPTPAALPFTTGPDCHDRAYQTNRTTPCSDRPGHSHWRKHYCTHINTYHDRNYRVCGACSDNTDAQPWAQQGHIDIMQIGFPGNNPFTPPAPGAAGGFPWPAGTKGTWTGFLTRLCKQCECLEQQKLWEFVNQTPGQYYRNWRRNNTPTYADWREPGDFPRNKCTCLFKLGTTGPAPGLGGLEDPRMCIRHRMRRWNNIIANRDRNDRWLRSIAIDKNTQELCTASPRRLSSRDCKSTQAYRACRCGSEVETPIQPASAVAGGAEVWQCMGCENLVHVVDPGGPSSQYQGPYDVDNLRETAERACKKSRSRGDVSLRREKLERKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBE1</accession>
    <name>A0A9Q8LBE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N-alpha-acetyltransferase 35, NatC auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758024.1">
        <property type="nucleotide sequence ID" value="XM_047902259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBE1"/>
    <dbReference type="GeneID" id="71982989"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03111"/>
    <dbReference type="OMA" id="NNWIHER"/>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="5">
        <location>
            <begin position="77"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="6">
        <location>
            <begin position="370"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="811" mass="92743" checksum="A7984989D831BAF1" modified="2023-09-13" version="1">MPGDGQASDTARLNDDSIDNSNHHGDDLSDEATAEARFGAETRLRQEAAQMRVPPAYTRSIRDVTADFVAASQQLPPGELVKDEFFTLFEAVGALEIMDPKMDSGYIEDGDSFEPDFDVTAGRELEEVLWIMDELLCLEMNFHAGYPLSQNVFTSLHVFRLIDPETKYPYYLARDEGAMGVEAHLEKDEESIRTGLVHVVLEAYCVSLVKCVALALEAIQGQTYYEEEDFVTYLFGRELLPYLTPEDSRKRLIEANNWIHERKTNLGEGRAAVLQSRIKNRIDMLLAMTAVEGYGHVKQGVMNFHGHDLARPVPEAFSHKVQRQLATSTPPRPQPTITWSEACELWSQMCDDLQVVEHVLLSDLRQNPQSLLREVWAFGYRDPHPSTFARAKMQEILILNEPVAQSTSTPHHDLLLRDIRELVLPGFDTADPASFEVELTSSPRHKTAEIMNSFMTMVYTAWLDLYLIACQNRCRMRRSYANELITWSKLLEEAPQYDQKLNKIRSHGFIRGDDGNRKHFKPLTHWTRYQYTQLKRWVIQLGFDTEIYLPDEYLGMYQLFRTTIMPEGDEGISPIERLHGKLLEDLRILGQRDLVGSPKDVQQLMAWRRQCSDSVSYVEVLVLFQRVENTMASAIGWMLSMLEHMKIVKPPNQSEAEARLRQEARLKPLIAGSARDEAAMLRADEAAQTWRRPGGIPINEKYIIRVTGVIEANKKTILDMIAKLTKLAKEAKAVGTEYAWLDELDLLKRTTFDMGINTLRVLQICQGHGGLDFEEGKDYGEFIELTILPPEHRQHAWWVVPQISEKKKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC44</accession>
    <name>A0A9Q8LC44_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">(R,R)-butanediol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03826</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758880.1">
        <property type="nucleotide sequence ID" value="XM_047902974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC44"/>
    <dbReference type="GeneID" id="71983704"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03826"/>
    <dbReference type="OMA" id="CAGGWYT"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08233">
        <property type="entry name" value="butanediol_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="3">
        <location>
            <begin position="24"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="2">
        <location>
            <begin position="185"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="357" mass="39025" checksum="9EA4BB6FAA103402" modified="2023-09-13" version="1">MKAARFHARGDIRVDEVEEPQPSDGQVIVDVEWCGICGSDLHEYLVGPITVPTTERPHPLSKATIPVTLGHELCGKVRSPPAGSKFKHGDNVMVDPRVLCNACLACKAGISHCCSKLGYIGGSTGFGGFGETVVVDEGKLYLLPPQIPLEYAAVLEPLVIVHHAMKVSRITDWRDKDVLVLGGGPIGFALLLCLKAAGAKNVIVSEPTALRREQVSHFCHTVINPSEENVPQRCSELTDDRGVEVVFDCAGAPRALPGALDALQFEGLYMMVAVWEQDITIPCWQFLAKHITMKGTLIFDDRAMSEVIQMIVDGKLQGYKKMVTGRIRLDDIIENGFKELINNKDEHIKILVSPKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCV9</accession>
    <name>A0A9Q8LCV9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cryptic loci regulator 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759567.1">
        <property type="nucleotide sequence ID" value="XM_047907764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCV9"/>
    <dbReference type="GeneID" id="71988494"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08616"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031915">
        <property type="entry name" value="Clr2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16761">
        <property type="entry name" value="Clr2_transil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptic loci regulator 2 N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="481" mass="53974" checksum="4EE7EF88A0289136" modified="2023-09-13" version="1">MAARSIPGYVRVATITYTGPAFGNASNRPSVDNYYRSDNYLRHTLAQKLMEEINQAEPSTMYFFDRLPPGLVGYENVRPFNEGSRNKGQIDRFIYGHPEGPFETLDRSYDHVKFLVFYGTPREGNACPCHRCDRKRTIGEKGVVRTKTPVPCPRMQIRDVKVLPEELKKLKLVRLIEVLCSGDQQGQTVQQTRSPLQAQHMQQAQHLQQPQHMQQEIPQPLAPPQQVQDMQEPQRMPNVSDAQRARRLQQARYAMQAQQLEELQQLQQLRRSLQDQRQPAPPQVVPPHLQSFYNQTMLPHTHVAQQHSASRDEVAIDPRLTASPQSAGLGQGEYQEMSPGIMESPAPRYGLSYPGPLPREPFIKQEDAQGPGGGILFSQQTGQAVGTKRSLDVQQEGETLDVGSSKRPKLQLSIGDAQASLHANSAFSQSKGKGKGKERQRPDDLHGDPETQLLPAFVKGYEPAAGAVQRGKVSPWGSFRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDP6</accession>
    <name>A0A9Q8LDP6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">R3H-associated N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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</entry>
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</entry>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040253222" description="NTF2-like domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2-like" evidence="3">
        <location>
            <begin position="265"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="666" mass="70186" checksum="6C6886373E5582E1" modified="2023-09-13" version="1">MKTCTLFSVIALASAVAALPQQAPRPPSYAQTDEDTNGNIENSPQRQQRPQPYQKQHNGAPNFSGDPKQNENEVDAVSGNRGSNNRPRPQSYGSTNNVNVDSNGRPSQQDEEDEISPQQNRRPQDSTNNMRPQKGNNRQRLGPANNGIMPEEDDQESEDEDQPEDEEDPQQPEDEEDQDEEDDEEQPEDENENHFSPQQNSNNRQRPGQSTSNNGIRPGGIGAHSGNYPQSRPGPIGGIGPGGIGSPQSNNNFGPASNPSQIGGQCVSRQEVNQFVRRFIGVLNRQGSDIGDAQATAEQIIAEDYIGISSSINTLEGEGDNGDTDSIAAESKQEWIDGMFNAPPFRGIQTLKVLVFCDQVVWYWNFASVGSGQFPVKGFNLFTLRRGGAQGSFQSQSQFSAGGSGSGSIGAGSSQLQGGASVQGSGSGSSSSHIRPSGLSGPGPASGVPTGNTIQAIKLETEFDSLANALDTGFQCTDRDGNDFQTSGGQGGPMGGMANFQNNRPQDQDQSQDEDDEDQLQPEDEDSEDSDLFQQKDVGTDRFGDIPPQSSRQGTNNVQFLQGGGGARLSTSQRQGSGSGSGNGRNFNAGTDSNDFDQALGAGINNQFDTASRGQFGPGGGGRLNANLNANSLAGEANGGTLDEARVQAQGRVGGGGGGSTGGGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEG1</accession>
    <name>A0A9Q8LEG1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EEF1A lysine methyltransferase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760255.1">
        <property type="nucleotide sequence ID" value="XM_047904234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEG1"/>
    <dbReference type="GeneID" id="71984964"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05086"/>
    <dbReference type="OMA" id="HWAVMDA"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="54"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="24982" checksum="38FA585355A8B382" modified="2023-09-13" version="1">MGSDEEGKALATPQFWDSRYGKSDGESPTHEWFRTFDALKPFFEAHLFQHRKPDSNPKILHLGSGDSTIPSDLAALGYKNQLCVDFSQVVVDLMSSCHAVDSGIEWRWADIRDMKHICAASVDVAFDKGTMDAMIHGSPWSPPDDVLNNTERYINELHRVLKDDGLFLYVTYRQPHFIRPLLNRDDIWIMEIENLATNESSFDYYGWILRKKSADHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEL5</accession>
    <name>A0A9Q8LEL5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760345.1">
        <property type="nucleotide sequence ID" value="XM_047904273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEL5"/>
    <dbReference type="GeneID" id="71985003"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05125"/>
    <dbReference type="OrthoDB" id="10518578at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="122" mass="13758" checksum="7461D1E5F958CAD3" modified="2023-09-13" version="1">MGASWRKKMDEVEARIKKEQGNLGVLDGEVKLKTKEKEYLKIKLQRLVREQENLREGSALEELSKVVAEQAAKTELLKSSNLVLEQHGLEVVSERKASGALKRKAEAARTEAMTIADCRRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFE1</accession>
    <name>A0A9Q8LFE1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760932.1">
        <property type="nucleotide sequence ID" value="XM_047904207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFE1"/>
    <dbReference type="GeneID" id="71984937"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05059"/>
    <dbReference type="OrthoDB" id="10621321at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="19168" checksum="E95EFD3E38660999" modified="2023-09-13" version="1">MPSKRPPSPSTTPDSDTVRPSRRHLPAPIVSPLRMQQAAELLASAKQECFETHQLWQDASNWGDSHSEVEAALKARLDINAETQADLENFIWLATNRALGIDDPRPEQIELAFKLAGRSPEKKGFCKCVGNGAGPSGVLERTIDLRDADVDWSTPSSSFLADEVEPRGESTWSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG62</accession>
    <name>A0A9Q8LG62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing YSC84-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761218.1">
        <property type="nucleotide sequence ID" value="XM_047903434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG62"/>
    <dbReference type="GeneID" id="71984164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04286"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="140"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="623" mass="67734" checksum="02059567A6CF0EB7" modified="2023-09-13" version="1">MSQPTMWQKVKSGSKAGFDKGYKVLDKLGTPVNRLSNKLGSEAFWPMELDKESDKAARILKSFCKDGFYKEEEVQPTDGPKQKQKVIQKIPESVIREAKGLAIFTTMRTGLWFSGAGGAGVLIARKPDGSWSPPSGIMLHTAGLGFLIGVDIYDCVIVINTEEALEAFTRVRCTLGGEISVSAGPVGAGGVLETEVHKRQAPLYTYLKSRGFYAGVQIDGTIVIERNDENERFYGQKLSVKQILAGNVRHPPFEVKQLMETLKAAQGDSDFDSAMLPTEPPPSDMDIEDGAAFGVPDRDDPDPYGVLALEKQGMSLREAGTNKRASWEQFSFNPSPTSPVHSIYNRQSQDLSARSTSRRNSWRTSAFSTEPKTPSSLRNSIDQGRSPVIMADSATQTDFPDGPPSPRRNSLRSSNSQRSSKGSISNNVHPYSMQNVPEHDVLATQDHKPIDPRTANGYTTPPRTPPGTQETPRNAAVYTTANQEDDDESDLDDEDIQIIEEPVFHSVQTVQPATSQVISNTSQVISKARIVEVPKRLPPKLPPRNPGRRGPVVVDASPTNASPERATSTDLPAPSVEADTAVLETAKLPSETDAKAGDLPLEAASAEHKGEIESVAEKLDDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH34</accession>
    <name>A0A9Q8LH34_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761634.1">
        <property type="nucleotide sequence ID" value="XM_047905172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH34"/>
    <dbReference type="GeneID" id="71985902"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06024"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="175"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43910" checksum="F96DFDC9F4D8609E" modified="2023-09-13" version="1">MQFPFAQYMVAAQSITVSQAEEYRRCLMFDKAFADVKARDMQQMWKAQDSLLKFEQGEALVEEDTTEVVSQFESGMLQALNDKIDTFRFDELVCPSDPSWPPEKFRTWLLRHDFSAQWYSALHTWIYTVSMSSISSPSRGVEGRDFLPQTLLPEVAIEYATAGIMDFRLHELRREGQRLRSSARLIQELAAWHALLPGKTVTTTSQTITPFWPSLLKYPTLLSIFRNNNFDIGTGHQALFGEICRINHDCVPNCQGNFNQNLDRFTIHSIQPIQQNEELTISYLSEHGALKESRQGRLRQQYGFLCDCPACDAKSPRGKVGEDKRVDLQEMLHEFAEDAEQRAGPSAEAELRMMVRMIEVYESEGIAGRELATMCMTAAEDCGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH81</accession>
    <name>A0A9Q8LH81_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase CSU1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761709.1">
        <property type="nucleotide sequence ID" value="XM_047905365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH81"/>
    <dbReference type="GeneID" id="71986095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06217"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000673">
        <property type="entry name" value="RING finger domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="305"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="414" mass="45770" checksum="FE9B03A9BC89876F" modified="2023-09-13" version="1">MEFWVSQKCELRVSFAIAGSNKMRSSPTIILLCAQPGSSESGSVESQGQAPRSAMSHSTRNTSLAFFTAHERNELKGHWGPKATRLTRDSFLPFGSCQLCLLPAREPVSCPSHGHLFCRECAVSNLLAQNKELKRLRKEAERRKLEDADEADIENAEAQARAVEEFERVQAGLSVRSGGNANERIIRRKNGKIEIEQEVDEAGRKGVKRKLEIDEHELVRLANDERDKVKKRRNDERNAKSELPSFWVPGEIPDHQNCALKAIKQHPTCPAAAADAAHDFTLKTLVTVNFNQDPSSTPDTPSRSCPSCTKALSNSTKAVVAKPCGHVLCKPCGDKFLNPPEKSAHEKEHDETVRCYVCHEDVTPGRKSKKKKDAETGEKESKVERGLVQLSCEGTGFAGGGSNMVKKERVAFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH85</accession>
    <name>A0A9Q8LH85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Emopamil-binding protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761747.1">
        <property type="nucleotide sequence ID" value="XM_047905129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH85"/>
    <dbReference type="GeneID" id="71985859"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05981"/>
    <dbReference type="OMA" id="VYLWLYL"/>
    <dbReference type="OrthoDB" id="5415655at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047750">
        <property type="term" value="F:cholestenol delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    <sequence length="249" mass="28311" checksum="9EFCA3A1F196B7CC" modified="2023-09-13" version="1">MSAEPPTFISTTTVYSLLSTVAILLTAYLASLTLLPRSTSTKIRLLFIWHAFDALIHFLLEGSYLYNCFFSYTTTLTDLANLDSIPASPYLPPSIYFLGHHDRIYGSEYGNNPFAKLWMEYAKADARWSGSDLTIISLELLTVFIAGPMAVYICDCLRKGKPEVWFWMIVLATGELYGGFMTFAPEWLSGSPNLDTSNWMYLWLYLVFFNAALWVAIPVWILYEAFGKISGALRLQERQRQIEVGKKAR</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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</entry>
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            <authorList>
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    <dbReference type="GeneID" id="71985536"/>
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            <dbReference type="EMBL" id="UJO17711.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="18773" checksum="9BF9902EBDFA00C1" modified="2023-09-13" version="1">MYQALLETQIGCAIGIEDESFLTTVTLAFSRMMFDFDRERKGQHIIVVDGDDTVWRYDEKIHNICTRLGIDPSWVVDHGWEPVSDEEFERPGLRMQMARGLLKGFQQTTGVKRPGGERQVVDLDVEQVKWSEKYGEAVAKQLRRRVDDEMADWEYLVQFKI</sequence>
</entry>
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    <accession>A0A9Q8LIR4</accession>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040481423" evidence="1">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10306" checksum="C667BBCBD3DE4856" modified="2023-09-13" version="1">MKSFAAIVASLAMLCGSALAAGNCKCQDPSGTGPQWNEYTEMCCENGNNVSCDKANYPVINAPDRATTSASSPTTLISAARALELLVLTAGIRRVDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ97</accession>
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    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        </lineage>
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    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="878" mass="97597" checksum="B08294859E9289C3" modified="2023-09-13" version="1">MPQQNGDKPSAASRKRKEPSSNSNQKDSSSSTKRPKFDHRAKQRDARVLSTQTASRAFKHGELDVDKFVKSREYEIRALEEGMARSKKALTKRAFQQVPPDLRRRTASHNVKRVPKRLQPRAKREMVEDKTPTVTARRRKPTRHMRLRIETAKRLRALGAKEKSARNADAASTLKSISLAIQTRAPKVKKATPAMPPVPKAKFRKRQKNKTWLPTHMFHAKRARMTLPKESMWRFALPLTSTLKSYRPTHRAANERGVVAWDTSYVSTIGLEGQQSSIEGLLQAIGVGTTLAKDDLAGAKVLKWKNGTRVWEGMVHHRGDPRRPIAPLTITWCALSTNERPTMGDEPAKRRRSVFVRVHPAAFWELWEEIIRLSKVAKPQVVVEDLRFELGSIEITGPGATEALHGALIPSAFTDDQPSSVTSIGHIWAQLAGIRGPAMLPSGALLGFEIQDPRLHHPPQTIKLAHKPENHDQMMEVIAKWPADETQSTPSLFLRRSRLAASSSLPSQKSINRRKALSAPGQYPDRLPLDPRIPILVQASSNAANQHGTWTIILPWKCVKPVWYSIMYYPLSTGGQPRFGGLDEMRQLSFQAGVPWFPGDFPGTKAGWDWEVQERSKRRADWQRRPKSKRVNWQAVDLGGGKKGEIGEGWACDWGRLLSGPPSAMGIGQADAVATTESMKNADERRLDEPAVQPEALVHISSPQAQTLWNSAASASPSIAKGSTVSVRVKLLTRGVPQTCARIYRLPSTTDSNALRQSWLTLHPRNQPSARHRGPKHGLPRLDKDAPAYLVQRRLAQSLIEPPRVGEEHYPDCPGEEDLIGFVTSGNYNLGEGKGTGVGSILLERVTEAGRAGEADGRLCIVRNAGNGIGRLAEWELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Q2</accession>
    <name>A0A9Q8P3Q2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756293.1">
        <property type="nucleotide sequence ID" value="XM_047901078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Q2"/>
    <dbReference type="GeneID" id="71981808"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01930"/>
    <dbReference type="OrthoDB" id="3650501at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF6">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41903" checksum="694C1D95DA3C1F39" modified="2023-09-13" version="1">MCPSHRFTESTMTRKINHLHWQTPTLLLCSFLVGVTLAIGHHCFYQSLHGKEVSAGSISIIGVQATQRQLVSVAGVSIAFVFKASLVLCASVAYIQLFFRANRTRAFTIETLDHWYAALEDVRSLFCISTYYRYPLLTLVALTAWLLPIAAVFAPAAISVTFDQIHPSMTRPLPVPRPAFDSLAFGSYVTNEWTKLSNATSIVLKGPSAEVSRIASAVAAGGNVLPIAPPASNTSWQVTFEAPRLRREDMDLNLRAAIRQNVLQALQESTANTKLYPAYDGSIGPVLSQYMPAYLSWTNASQHDTEVPSVKTSNKWELIAQRYLYDAELSTNLYVGIFPRALNSSSLGPDIFHGKLLDHNEARAERRNQRRTGARNNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Z5</accession>
    <name>A0A9Q8P3Z5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756906.1">
        <property type="nucleotide sequence ID" value="XM_047900443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Z5"/>
    <dbReference type="GeneID" id="71981173"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01295"/>
    <dbReference type="OMA" id="YGLQQNF"/>
    <dbReference type="OrthoDB" id="5951731at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04271">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006586">
        <property type="entry name" value="ADAM_Cys-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034028">
        <property type="entry name" value="ZnMc_ADAM_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00608">
        <property type="entry name" value="ACR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040477529" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="7">
        <location>
            <begin position="23"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="9">
        <location>
            <begin position="280"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="8">
        <location>
            <begin position="533"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="752"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="829" mass="88239" checksum="74FAF54232A3D0F0" modified="2023-09-13" version="1">MHFLPFTLLSLAASILSPLASASSTIRNPIGALSAVQNATIHTHNHRLTALSDFELSFNIRDDVHIKLSLEPNHDILGEDTTVTYLAPDGSVARREGVDRLGHRVFKGVAWAQRPSIGQNQWQRVGWARIAVTQDGAQPVFQGAFSVNHDNHHIETSTNFMRTRHPMDPEVDSSEEYLVIWRDSDILDDVAHYGQHNDLRRSIDGELGSCAADRLMFNARDDHPVYMAMKTKRSSDDKSYGFMDFSNIFKRQIDSTSGGRSAGVNLASNIGNTAGCPSTRKVALVGVATDCTYTAAFNSTQSARENVIQQMNTASGIWENAFNISLGLQNLTLSDANCPGTPNSANEWNQRCSDDVDIQDRLNLFSAWRGNQRDSNSHWTLLSTCATQTAVGLAWLGQACVGTAIMTNGSVTGNGQTGGSGSETVAGANVVIRTQGAMEWQVIAHETGHTFGAVHDCTSSTCANQNIVNSQQCCPLTADNCDAGERYIMNPSTSRGVNTFSPCSIGNICGALDRNSVNSQCLTDNRGVTTISGQQCGNGIVEPGEDCDCGGEAGCAGDTCCEPTTCLFTSGSVCDDANEDCCRSCQFASAGTVCRASTGDCDPQETCSGTGALCPEDNTQPDGTDCGDGLECASGQCTSRDQQCKSVMGSYTRGNDTYACGTSGCAISCASPEFGTGVCYGLQQNFLDGTECGGGGRCANGQCKGATTGGQIRSWIDDHKALVIGICAAIGGLILFAILGCLVRCCKRRRRGSKRVPSGPPAAPPGGWQGWNAPVMSGAARGHPNMQQQQQQHPSHGWFNQQHGNTGGWTPPPVPPPAYQQRSNSMRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P460</accession>
    <name>A0A9Q8P460_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinesin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756773.1">
        <property type="nucleotide sequence ID" value="XM_047901376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P460"/>
    <dbReference type="GeneID" id="71982106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02228"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32721" checksum="16B0DDA90885C72D" modified="2023-09-13" version="1">MSYEQARRINPEATNILDQWAFLHHGDVSYELIRTYPEMSKRDQEEGGIEDMLDFATDEPAFQDSLGVLAQYFLVNAIDGSAGFSIHPVMHRWTLHRIVDNKAREALCARAIRIVARRVPLVSGTGQQIRAEGLLPHARVVATRLEKETGVTGVDYDLYVMAHFVARCERSQTAEFLYLRALTESEEAWGPEKEMTLGICSNLGLLYRNQDKLQKAKDVWLRTLVGMEKKLGPENATTLQTLDSLGALYGRQGKLKDAEDMYLRALRGKEKALGQSHDSTLRAAWNLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P473</accession>
    <name>A0A9Q8P473_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab proteins geranylgeranyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757146.1">
        <property type="nucleotide sequence ID" value="XM_047899866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P473"/>
    <dbReference type="GeneID" id="71980596"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00718"/>
    <dbReference type="OrthoDB" id="1923006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017230">
        <property type="entry name" value="Mrs6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037514">
        <property type="entry name" value="Rab_ger_ger_transf_A_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="571" mass="62277" checksum="F58F355878BDEC6A" modified="2023-09-13" version="1">MPTQRHRWVHFVTRARCREEGRTQSSAEEVLSCGNGTCCPATKVFEPTWPHLPLSNINRAICERPTTMESLEDTNWDVVISGTGLPQSLLALSLSRSDKKILHVDRNDYYGGDEAALSLSEAEEWTQKHAAEEGDAKTSFSHATVSKPTEDEVSTTTKLGPARAYSLALAPQLLYTRSALLPAMVSSRTHSQLEFQAVGSWFILDEAPQDADTPTRLIRVPGGREDVFQDKSLDLKAKRSLMKFLRFVVNYDEQLETWQDDRTKEFSTFLQDKFGLPSSSHAPILALTLSDRPTQEISVEYALPRVARHLSSIGMLGPGFGAVLPKWGGLAEIAQVACRACAVGGGVYVLGRGIIDVQSDDDFNLRVELSDGQKVTTKWLAGLQQDLPGTAPNTAETTSLMKTSNTISVVSSSLNSLFPRTSEGGVTPAGAVVMVKPAGETESTIHIFVHSSESGECPPGQCVLYASCAENASRGFAHLEQAVVQFLQSVEEPTTPQVLWKMQYQRTVPASSTTTMQRTGSVITLQHLSHDLAMEDAVLEGVKPAWEQITGSIGDGYLTFEAREGQEGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5B7</accession>
    <name>A0A9Q8P5B7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758209.1">
        <property type="nucleotide sequence ID" value="XM_047902323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5B7"/>
    <dbReference type="GeneID" id="71983053"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03175"/>
    <dbReference type="OMA" id="AYIKYKM"/>
    <dbReference type="OrthoDB" id="3897607at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="35"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="41974" checksum="9130A05B86A1DCAE" modified="2023-09-13" version="1">MATTYSVSPVAATDRAGIVWVAAILSLMFAIITLATRFQIKFHTLGKDDWLIAGATIVALGQFVAVYVGLHQGLGQSTLLLSQSHAAQLAHAVLASEIFFIVTMMLSKLGVIFFMKRLFTREHRTAWWCCNAAVALTIIWGVASVSGVSIGCGSWKMLYGPARCDGKLARWTVVISTDAAREVVYVALAVVLVWPLQMRLSIKVTVVMAFGFRLVCAIFAALHRVWIAKYVQSPDPGLAVADVLVWQQVALGYSLIATTIPTIKNFVRGYNQAMGWDPSSEKRGLGGGYNLASHVRSGGRSRIESSSKRGSGSRNMDRPEDQLQLRPNVGDYRVGAFHDSSKGKTPRRLSTSGSNESEDPIIRRQISVTIEHEQASRANSSNLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5U1</accession>
    <name>A0A9Q8P5U1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase ksp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758719.1">
        <property type="nucleotide sequence ID" value="XM_047901787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5U1"/>
    <dbReference type="GeneID" id="71982517"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02639"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000693">
        <property type="entry name" value="Serine/threonine protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="548"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="591"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="677" mass="74218" checksum="D4DCFAAD730CBBC5" modified="2023-09-13" version="1">MACMRDGFQHGISLDNGRFMTVSPLNHGSFGMVLAAKDNITGEDVAIKCLTKPNATSPTTTCPAAIAIDDRSEELDIHSRLARHPNIVNLLHYFETENHQYMVLELCNNGDLYEAIRLGKGPLETGHVRDFMLELVSAVDHMHAHSVFHRDIKPENIFLTGNGSLKIGDFGLATTETWSTEFGVGSDRYMAPEQYDASVYGYGYSPAAADIWAIGVVLLNILFQRNPFATPTIKDPLFADFARDRQSLFDVFPNMSQDTYNVLVHCLALDPANRSLAAVREALNDVVSFTVDDESLDDFCTDQLDNVPVATAAREPLRTPSISSPALAADSFPWSAALLKTPQKASRQLSTIRDEDMELFPGTANNAEWQYLDTDEVSLSSNLDSGLGMSYKSTKSGKSFLSTNSVKPKSGFVGSLPISFSKPSKSPYGGTTSGFSKSWSDLWDEEEELQEELEECHPFQDSSPEAAGNDIERVSTAKPSTPRVQSVREDDRGSVTPRPGLANIDANVCSATPMNIPGAEDKKVTDLPKTKSTSILDKWAALGNFRRARQESAATAAATATPPKTKYSDAFASFTPFGSSKKVKATPAREATSNWRQNSGSPTRLRSTSFNSSKVWQDNNWREHKSPAPKKASPPLSIARLGGSQPHNTEKNFLDDEFEDADLEWVGLPSGWRDFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6G7</accession>
    <name>A0A9Q8P6G7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759350.1">
        <property type="nucleotide sequence ID" value="XM_047907825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6G7"/>
    <dbReference type="GeneID" id="71988555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08677"/>
    <dbReference type="OMA" id="EFESMSH"/>
    <dbReference type="OrthoDB" id="5423493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="663" mass="71868" checksum="F650D954222DA56E" modified="2023-09-13" version="1">MARLRNAPASEATAAVPATRTTRGRPALKEKTNTTRPSTAPVYEDDGNMDDLIKDAKPKRGRPKKAPQLSDELLMTSGLGLQDGAGANQDSEAPMTTDELAKSDDVPVRVAIAKPNRRPARPGRKVLHNEQQNKVLEGLKQRMEATAKDQRAKPAPKAPLETAEVDSDTIVVAQRSSVKATEPPVERSDFSLSPSPPPPGKLSTARRPSVVQPGSALRLQNTPAVEASMLALKNFKRRPRQLSMLQMVQQRTASARPSLANTAAADPAVQDTSVFDLDVSDEEDDFAPEAEGTPLKVTKAQRKSSAKKTAAVDDEFKSKSSTKKRKSTDVDSSMVSLSSSRSKRRKSTRDEDEVEESLPAAHEFAALPTSSARAATPLPAETSDIQVVNSPSTSTPPTEPSSTRHHSPDKEDDFAVPSTELQEPLVRSSPTPELEDEADGAIPNGTMAEPLSSSPVHRASKIMDSFDAPPMTQISPPAKPQRKKKVKPLTTSALQSLLPKKRAPMRAHRKKTEYDLESDSDEEGSQLDASHLEDDEDELGGALRRKKATPLKNAKRGRQGKGTTARASSKAPARKAPAASKSKKASRTYGRAATSDKENDGYDSAEEEEEESTLPEVSISMEDASLSKELEDAKKKFAEVDDFDMEFESMSHEDHRSSSQGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P709</accession>
    <name>A0A9Q8P709_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="11">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PIM1</name>
        <name evidence="17" type="ORF">CLAFUR5_08128</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12 13">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="11"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P709"/>
    <dbReference type="OMA" id="WLTNIPW"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141164">
        <property type="term" value="P:mitochondrial protein quality control"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000113">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 11 12" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="16">
        <location>
            <begin position="188"/>
            <end position="471"/>
        </location>
    </feature>
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        <location>
            <begin position="912"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="46"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
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            <begin position="841"/>
            <end position="870"/>
        </location>
    </feature>
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            <begin position="1106"/>
            <end position="1138"/>
        </location>
    </feature>
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        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
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        <location>
            <begin position="841"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1108"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="active site" evidence="11 12">
        <location>
            <position position="1004"/>
        </location>
    </feature>
    <feature type="active site" evidence="11 12">
        <location>
            <position position="1047"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="624"/>
            <end position="631"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1138" mass="124999" checksum="D9BBD996AD462F7C" modified="2023-09-13" version="1">MLYGRGQAWRTALRSSSHRAYTTTRAPCRACQAQLTARPIARQAPHTIQPSCLPSSITLSRDLSSSPARRKQKPSIDPEDGAEAKEECGGEVKEKEKDNDKEKDNDNDRDFSKDNDQDNVEAKAKSSEPTPIHVPGADGKAASAGGRGSGDAGNGNPSGNFGDGGNRKRKAQGKDLAKPQVPDVYPQVLAIPIAQRPLFPGFYKAITVRDPNVVAAVQELLKRGQSYVGAFLLKDPESSQDAINDPSEVYDVGTFCQITGAFPAGHGADKALQTVLYPHRRIKLSELIPPNRGPPAAPEPEQAAHATLETAHPTPASTPEEAPKPTEGEEKSGDVVASFEEKDVSAEQKKEQEQKLLQPTDFLRSWPVSLVKVDNLADEPCDKRSPTVRALISEIVNTCKEIGSYNHLFRDHVSAFAMSQSAANIADEPAKLADFAAAVSGGEMEEAQNVLGELNIERRLSKALEVIKKEHMNAQLSNKISKDVESKIQKRQREYWLMEQMKGIRRELGLESDGKDKLVEKFKEKATKLAMPEAVKKVFDEEVNKLAHLEPAASEFNVTRNYLDWLTQIPWGQRSAENFGIQHARDVLDEDHHGLKDVKDRILEFIAVGKLRGTVEGKILCMVGPPGVGKTSIGKSIARALNRQYYRFSVGGLADVAEIKGHRRTYVGALPGRIIQALKKCQTENPLILIDEVDKIGRGHQGDPSSALLELLDPEQNNSFLDHYMDVPVDLSKVLFVCTANMTDTIPRPLLDRMEMIELSGYVSDEKMAIAERYLAPHAKELSGLKDVAVNLDKEAILELINKYCRESGVRNLKKQIEKVYRKSALKIIQDLGEDAFSEEKAMTDEGKAAAEESKKDESDVKETPETIEQATTEKTRVALKVPDSVHVSIGKDNLKDYVGPPVFTADRLYDVTPPGVAMGLAWTSMGGAALYIESILQNALSYNSRPGLERTGNLKTVMKESTLIAYSFAKGLMAKQYPGNKFFEKANIHLHCPEGAVQKDGPSAGITMATSLLSLAFDKPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGARMIIFPRDCMSDWLELPENIKEGIEGKPVDWYSDVFKLVFPEIDESQANSMWKRDLAKPPKEESDKGSSGIPDELYSGNLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P770</accession>
    <name>A0A9Q8P770_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_04377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO15748.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903525.1"/>
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    <dbReference type="OrthoDB" id="3650306at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="68"/>
            <end position="229"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="619"/>
        </location>
    </feature>
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        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="619" mass="62832" checksum="74242BADB3B777D8" modified="2023-09-13" version="1">MSGEGQSGRGVTDALTAGVNYLTGSSNTTATGNSAIHQDGVEHIQNKLNERGDSGRLAIPEIADPNLIADPNTISTPGLSSQDTPGTSSRNFPLNTSGSTSQSGLSQEGRPQTLPTSELEQRELVRGERGEQTGLPRQVADSYRTAPDVAPQTTGSAEAIHDKREVQQELEGIVAQPAPATSEGVGHGTGAALGSGVISSSHTGAAQSGAVAPQSATGTHGVHGSGYPAVGTEQTVTGIHPGAYTDSGVRGGGVGTTNQTGGVGPVGGASTLSSAPGQYNQGVDFTGHRSAEEVAGHVAGLDAESTRGVPAPKAGWHPDSDAAADGSERGAKDLSAPGFTAGAAHATSGAGLADRTRDDPAFDKSGHSTNSDLTAGAAGLGAGAVLSNSTRDDPAHDPSGTFVPTTQLDGSDRQAHTSEHHTSALGAAAGGAGLAAGVAGAEATRLHDNDTTRKERTDPTDIATDKFRRDPTHSASDDAVLGSSAAGHQASRGETGTSASDLNSTSKERTDPTDSATEKLRKDPAHSASDDHVLGSDAQGAQANRGEHVDHKHPEGHQLQPTSTGKDDPYWQGKESAREHLEHEAREGRTVKENPDSIPTAGGEKLGRKHWGESKKLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7A5</accession>
    <name>A0A9Q8P7A5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antigenic cell wall galactomannoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760058.1">
        <property type="nucleotide sequence ID" value="XM_047903504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7A5"/>
    <dbReference type="GeneID" id="71984234"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04356"/>
    <dbReference type="OMA" id="FAMEFDA"/>
    <dbReference type="OrthoDB" id="3485059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF4">
        <property type="entry name" value="CELL WALL GALACTOMANNOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040250347" description="Antigenic cell wall galactomannoprotein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="20900" checksum="086B08DE0C47F85E" modified="2023-09-13" version="1">MRSVFFTGLLATLAIASPIAVVEKRGAANIAAALDNVSANIKTVNSTLSTFNKGDLDSLIKVLKIQQQTKDLGESLKTATSAAEASEPLDDAGSLTIGLAILNDLLPDTTSLLTKIESKKPAFDAAVLGIASVSATVKKSLVEQKQQSAELGQAITAKLTPAFANLAPGINQQIADKFTEAINIYSQPGGLIPLPALPFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7N3</accession>
    <name>A0A9Q8P7N3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760670.1">
        <property type="nucleotide sequence ID" value="XM_047903450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7N3"/>
    <dbReference type="GeneID" id="71984180"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04302"/>
    <dbReference type="OMA" id="FATAWCP"/>
    <dbReference type="OrthoDB" id="5181940at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="199" mass="22254" checksum="861C83909F6495E5" modified="2023-09-13" version="1">MTAIKDARLYDDIEAIKALIQAFFDRVNNNDPQGLQHLFVPSAHLTILRQFPDLAPPQTSPWSELPQPSLTSTTSNEQKISLVYQSSIEAFIKLIEDGNKRKDPKKPVPKVHEVPDLDATDVKVDGIFATAWCPFSVTFDGVLHHYGTFVYTFGKDGHSSGGLETEKDLKLETLVQSYRRTPGWGEDHSDTSAELSRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7N8</accession>
    <name>A0A9Q8P7N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760716.1">
        <property type="nucleotide sequence ID" value="XM_047904041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7N8"/>
    <dbReference type="GeneID" id="71984771"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04893"/>
    <dbReference type="OrthoDB" id="4848667at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="368" mass="40193" checksum="5F3B48D65DD49FB2" modified="2023-09-13" version="1">MGPTNYPPPSAVTTDATCSITSGQQLQDFLESDASLFSGSQATNAGTEGVELDFLDSLSFPDVPAYNPALETDYVNFDAFHRNGYPTIKDFSSSLPRSHDLGELESGFQGLLDESRISSIIDSMVESPLQDDRSACVTTSHRITCRGSLTHGKTCKCHIMWNKLYLIVTEPKLSQTTKLLPLDLVLFVEQVLQNNVEMMRHCSACESSKLPSVTGMGICIVASWIIETLYVALKSELELLGTSTTASNISRGRSEHNNAEPSGPSKEHDPNSCDPTGIPPSMDARNCLRVGTWTLPKELWALCMSAIVARRIERLQRLLMTVMSHGDQVAEAPAGFKVGHGIAQGICARAEILLGMIETWVARYHLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7R2</accession>
    <name>A0A9Q8P7R2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760791.1">
        <property type="nucleotide sequence ID" value="XM_047903492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7R2"/>
    <dbReference type="GeneID" id="71984222"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04344"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13568" checksum="06D642A886321328" modified="2023-09-13" version="1">MMYHKALLMGDKDVAARILQADTPAKAKKLGREVRNFDQMVWDGSCDGVVEAGNFLKFSQNEELGKVLVGTEERQIVETSPNDRLWGIGFNTEEAEGKEGEWGENKLGKALEWVRERLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P849</accession>
    <name>A0A9Q8P849_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extracellular serine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_05137</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761074.1">
        <property type="nucleotide sequence ID" value="XM_047904285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P849"/>
    <dbReference type="GeneID" id="71985015"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05137"/>
    <dbReference type="OMA" id="CERFDVY"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000165">
        <property type="entry name" value="Serine peptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040242219" evidence="6">
        <location>
            <begin position="16"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="556" mass="61343" checksum="64ED2B176CE06350" modified="2023-09-13" version="1">MKTIVLLASAVLASSQSYGGHGGDHGHGHGSWGHDHDWDWNGGYPHGGWGGSCQHMPGGEPPAYGTQNATFEQLIDHNNPELGTFSQFYFYDDRYWKGPGSPVILFTPGEVNATRYYSYLSTNRTTGLLAEEIGAATIVLEHRYWGVSSPFADLTTENMKYLTLDNALKDMTYFANNVKLPFAKHASSNAKDVPWVTMGGSYSGALSAWLASVEPGTLWAYHASSAPVEAVSDYWGYFKPVQEGMPQNCSKDVSLVIDHMDDILMHGSDQEVHDLKAKFGLETVEHNDDFMAALENGPWLWQGNQFYTNTGFFTWCDYVEDSVNKTGSAVAGPDGVGVEKALEGYAKWWVETELPTYCSAYGYAEFNSTNNTACLDSYNATSPLYTDTTLSNVVDRQWVWMTCNESFAYWQTGAPEGRPSIVSRLVTPEYWIRQCGLYFPPGPNGETYGIAEGKTEEQVNAYTGGWNIDNTTRLIYVNGDNDPWRECGVSADLRPGGPLESTEQVPVEIVPGGYHTSDLITQNGAVNSGVKAVQDRIIAQLAAWVKQYPKKHCFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8A9</accession>
    <name>A0A9Q8P8A9_PASFU</name>
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                <person name="Stergiopoulos I."/>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF17784">
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    </dbReference>
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    </evidence>
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    </evidence>
    <sequence length="170" mass="19275" checksum="F61967D3D906382B" modified="2023-09-13" version="1">MTRMMMEGAVTSPNLARGVLFGRHAQRLHAEGSTLTLYYSFKAHFTYSLCRALSILGYENIYHGLEVANALPSVQKAWTLLGRRKWGPGAAIDGREIRLENFDALLGHCEAVTDQTCACSISATFGVYFRSASYPYFPSFSTSLYWFKQVFLMYEKRVLPKLDAANWQTY</sequence>
</entry>
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            <end position="84"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="172" mass="19404" checksum="61B73C47C2A8B6EE" modified="2023-09-13" version="1">MGYCPPTTLLGRKYGPSVGLLRKTHDGYLDEVQLASKRVTRDSRQRRRQRASKCEDDAIWDDEEWQEATLHGEEHENENDDVGDDATGSCSDTADCDEVEEENDDTADMVDELSKHGFDYFGHIATTNKATAKLPQEILDILVGHTIPTALETYRRLPSTGYTLHAINQEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="2 3">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <begin position="342"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="383" mass="41122" checksum="07533D9881985454" modified="2023-09-13" version="1">MSTLIMNPPPHRKPVPGGQPSFTMQTPKPPPAQNYPGSQLSQQERTHSRTRTSSSSVMPFSVNNYSPPRQPSVSPAYSMTQQSQHQQQQPPYPGQNRRTLSNATSSTSSTNTSANLQRVPTNSAHSTTSGVRRSTSSRSNSSISPTSYVALMRKQKGTVWCDRAQHEDPRILAAQRQAKMRAAAEVAGGHNYATQVRTSTSSSGMVGGVRSKIRHHGAAKASAYKATLHPGGAGVPMRLSASEVDDGNDSDEESSGKYHQRSGSGRSSVHSGRRGQSHNTSGLSHSRSNGSTPPQASPVDSMGELREEETPTANGGNDEYFAHDEDSFGTVAGLPKTNGPTAEERAHRNTADDLRRRGSVDDRTMTMSNTRLFIANPDADLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA43</accession>
    <name>A0A9Q8PA43_PASFU</name>
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        </recommendedName>
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    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763048.1">
        <property type="nucleotide sequence ID" value="XM_047906702.1"/>
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    <dbReference type="GeneID" id="71987432"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07554"/>
    <dbReference type="OMA" id="WTYFTST"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
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    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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            <end position="283"/>
        </location>
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            <end position="347"/>
        </location>
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        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="347" mass="39712" checksum="5A01893B4F6EE855" modified="2023-09-13" version="1">MATADWIQYGAPTLDRPFGLQLWPTFAKAFEAVRGYAPEDFRFVPGKTPMATMAETAIGLISYYIIIFGGRELMREQQPLKLNGLFKIHNFYLTAISGVLLVLFLEQLIPTLARNGVFYAVCHYNGGWTQELVVLYYLNYLTKYLELLDTVFLVLKKKPLTFLHTYHHGATALLCYTQLLGHTAVSWVPITLNLTVHVVMYWYYFQSARGIKIWWKKYITMLQIIQFVIDLGFVYFASYTYFSARYFPWLPTYGICAGEEFAAFAGMGILSSYLVLFIGFYISTYKKPVKKGRGRATSALVEMKDEQIPDVKEVRRRLSGNAQTMNGYSTSKENGTPNGRVTRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAT6</accession>
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        <name type="scientific">Passalora fulva</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
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            <begin position="286"/>
            <end position="370"/>
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    </feature>
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            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO19006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBG0</accession>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71987504"/>
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    <dbReference type="OrthoDB" id="5598695at2759"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO19378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="44881" checksum="5E12EBA9AE3C0D09" modified="2023-09-13" version="1">MPSEYYDYADRVPDSEILRGNSDLLKHDNLYRTVRKYSYAYIVEEANTRQIGSSISEQTLRSRMSAATEHIAERDGRGIRDVTQELRHERESNGLINRRRSSSKITGLRDDSIALAVQPSESITARGRSASDAGMSHRSTVGCVEDQRGSSAALNEVTEAEDLMKTLVHLVQQISSATAQHFGLSARQQSPFAPSELCSTFLAPLLEDFLSRDWRTAVPALQQREGLRVTDMMSGLIWSFIAREIVGNRSGQHLPSSPTPPKPKLHNTIADDVAGLIDALIISLKPYMARLEILSSLFAWQVDQLWHEPLHDTLEQLITQALRLKWAIAHTHGCTFTFVWPAYGEAFQPSVMQAVAHPSVKEAHLVAVPLSMGLYAEFSFCGEAVKHTIRPAEVRLCHHSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBR5</accession>
    <name>A0A9Q8PBR5_PASFU</name>
    <protein>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBR5"/>
    <dbReference type="GeneID" id="71987558"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07680"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="93" mass="10632" checksum="169D1871DFB6000C" modified="2023-09-13" version="1">MSRVPPFRGGSNYRGAYRHGSLHDLIVDREFHGGLYNQYGPNYHGVPSARLGYGGSWQGRAGPIFYHDMQRHWMGMQRGNVRNYGYLNPGGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBW8</accession>
    <name>A0A9Q8PBW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBW8"/>
    <dbReference type="GeneID" id="71990382"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10504"/>
    <dbReference type="OMA" id="EPNNEPY"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="36033" checksum="10BA2A6073F88EA4" modified="2023-09-13" version="1">MATEEYGKEDENWFQKALNLSPRLRHQRSGSGSSNQSGKRRSWLRPIPESLHKEPQLPKPAMASKTFLITGAGRGIGRGLSRLLLQKGHRVILVDYNQKELYHTADKLGQTFRDGHDFAAIECDLRDPQHIKGAAEAARRMFSGNLDCLINNAANTSGVGGSHLSELSLEDWNASIETNLTAPMLMSQACLSMLQSQGSRSAGGSIINMSSTRAKMSEPNNEPYSATKAGLLGLTQSMAVSLGGLSIRVNAILPGWINVSNENKDADEEGQSWEEGLNKNDHEWHLTGRVGKVEDVLRAVEYLVESEFVTGEELVVDGGVTKKMVYPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCH1</accession>
    <name>A0A9Q8PCH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764304.1">
        <property type="nucleotide sequence ID" value="XM_047909576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCH1"/>
    <dbReference type="GeneID" id="71990306"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10428"/>
    <dbReference type="OrthoDB" id="42525at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="23724" checksum="D003B7186A6AD5D2" modified="2023-09-13" version="1">MAGKWHTQNDAPTVKDPTADTFKITALPKTDIWRRTDDDDVFNAPMIYQKLKASDFKSISVTIFAPWKTQYDQGGLILAFPSESGDLKNSKWIKAGIEYHNNVSVLGIVGTDRYSDWSIAPMSQEHHQKARFRFERDGQTLWVYGAQEKGEEKLGPMREVKWAFMEGRLEQEVWVGVYAAKPTTNDDDVEGEVGVEVTFSGLEVEVGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCW2</accession>
    <name>A0A9Q8PCW2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764471.1">
        <property type="nucleotide sequence ID" value="XM_047909474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCW2"/>
    <dbReference type="GeneID" id="71990204"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10326"/>
    <dbReference type="OMA" id="LLMCGQF"/>
    <dbReference type="OrthoDB" id="203824at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="770"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="788"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="965" mass="107681" checksum="BE6FF414982F0F51" modified="2023-09-13" version="1">MSLQQSQQQQLSDSLQPSQAAPAYFQALLDRGQKRANTNDEPQLQLGLQDIARKVRNLGKGFTDARAHYLLSASGVNTSEALRDLEDLAGPPSSIQQPIEPVATGVKETLAREHESDFQQMVDSHIKRAHAEFDQMIEERLHGVDWDAHRQRIYEHFGLKRPQNQDGGNTIGGASVNGGASTFGRSSRRGRISTANRSTFGIPGMSKSIIGSVGPRDLKQSAFNDIAHKLPADGFRAAPNDSILRKKQDKYADRVKDLNVARLQEKVYPLLTKFAEVEAEPSHEDTSMLVNAFKALVHITGEDASKENTSEPGVVRERQYAKGYIDDTGGAENVMVRKRIIDGSRTFLEKLFYSQVQTTVARNPTEAHTGGTPSALNVVKGYVRVRALRKELGNDMDALQQVNDDYGWAVMFYLLRSGLFDEASAYLVENKDAFRSIDSHFVKYLEHFCASPDRRLPPTTQTSISNAYSMLSRLGPQGAVDPYKLMCYKVLGRCDLGRRTLDNITNDMMDWLWLQFALAREFNRVDEMAHEAYGLYDVQQSIEEVGNRYFQPGTEIANATTTFFFMQVLAGKFEKAVADLYPHNYVSAVHFAIGLDFYGLLRVSDISNSDDLLVLTVRAQHQIAFGSMIGLYTRDFRTANVTAAVDYITLICLNADLQPENLGKAQRELCHQALTEVLLETREFSQLIGDIRADGMRIKGAIELRLKLIGLGNEREYLRQITLVAARIAEEQGRTTDAALLYHMCDDYDKVIQVVNDAVSLALTTELGEQPARLQPLKPRNTDDHNNQDPNQEQASLSLTQNEDPIQLAQDILQLYKSDGMYLNKMSRKYSDACEVLLQLAAARKELENGRWSQVVDSVTASDVIPTEAAGNISAIRSKSQAFDLMPTTVARTIGHVMVWTVVALSNQVNRLRSQEYETPAINEAIARCTQSAKDVMVFAGLIRYKLPGRVWETLARAGQDLGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD96</accession>
    <name>A0A9Q8PD96_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily multidrug transporter mfsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10013</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764681.1">
        <property type="nucleotide sequence ID" value="XM_047909161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD96"/>
    <dbReference type="GeneID" id="71989891"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10013"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF2">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="20"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="567" mass="61146" checksum="97CEFD2055B7E5BF" modified="2023-09-13" version="1">MALTSTRLTPRDPNKFPATQLFLLALVRLAEPIAITSIFPYAWKFVLHFNVGDKSNASFYAGLLISAFSLTESLTGVFWGTLSDKLGRKPVLLLGCIGTLSSLLVVGFSMNIWMALAGRFLGGALNGNIGVIQTMVGELVINPDHEPKAYAIMPFVWSVGTMIGPCIGGFFASPADNFPDTFSKDGLFGRFPYLLPNLICAAFMGVSVLTGYLFLEETHPDMQPWSTPQDLEDTNAKTPLMPAQASSNTPAVNLEDASYGTFNAVDEEAIVEEWDIKPDGTSRPASISSGSGPKVFNKRIIMLNIALGIFTYHSMTYDSLQPIFFQDDRVPSSANIENLVAAATASDSGSLAGGLGLSIQQVGVIMFFNGLIALVVQGVIFPPMADWLGIWKLFIVTAIGHPLAYFVVPFLARVPVKMVFPAIYACLTVRNLFSIMAYPVLLILIKEAAVPGSLGKINGLAASVGAASRMLASPVAGYLYGIGMKMDFTAIAWWASALVAVVGTIQAFFVNRVKDGPQHRIRGVAPCRFVPDEGREHRPSVVHIKIHDTDSGYNSADERTPFASRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDL8</accession>
    <name>A0A9Q8PDL8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764904.1">
        <property type="nucleotide sequence ID" value="XM_047910519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDL8"/>
    <dbReference type="GeneID" id="71991249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11371"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="23545" checksum="6EBD06F15AC0AAE1" modified="2023-09-13" version="1">MRRTRRSRIDNYFQNFFTWTESNDADSTGSFNGGFEGNQEMLARYVGRDVHKLPLIAPGLKYNRGAGLRMALEVSAGTAGSFDGMHCELVDTRSKKPDAVIWGHNYGIVVNKSCQRLYDEGQRHLFATFEMIALDCWKDQNMSCYFVTDDPIMQRFKGSWVYDTTEVPPPEEANTIEELAEKLGLDAQQLKRTVTNTTPPSTINPLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV1</accession>
    <name>A0A9Q8PDV1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase RNF19A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11476</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764978.1">
        <property type="nucleotide sequence ID" value="XM_047910624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV1"/>
    <dbReference type="GeneID" id="71991354"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11476"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097039">
        <property type="term" value="P:protein linear polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF13">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="184"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="398" mass="44179" checksum="AD802604FFD536CE" modified="2023-09-13" version="1">MVPASSGLQAGLNPTPTRAVCLNSRAAMAAIKEKDSRSTLKLGTSRIVKELLKAAWHRITGPHRRCVKRFRSKKKSRGDGDQQWCFATAHAQALPRAFVIVDPPINNAAPDVHVVDVVRARPEEHVGSDAKSEVALLERMSGVEAVDEHLFQGLAPSSELARTLSVTSRPKPRSKRSSSGQNETALQCTTCEHECPEEERFPSVPQACAETHEAETCLTCWQQWLEVQVGSQSYDQISCVQCSNKLNQLDIKRLATTAIFEQYLDAEAKSALATDDSFTWCLAPKCSSGQLHYGNEHFTCAQCGHEHCINCRVDWHAGETCRAYTRKQNEHAKTKKESKLLHARLRQEEASTAAMIDDETKLCPGKKCGRRVVKISGCDKVTCTTCRYTFCWLCLASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE53</accession>
    <name>A0A9Q8PE53_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765275.1">
        <property type="nucleotide sequence ID" value="XM_047910436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE53"/>
    <dbReference type="GeneID" id="71991166"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11288"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040463368" evidence="2">
        <location>
            <begin position="19"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="198" mass="18145" checksum="0F6A8A5A8CDF9574" modified="2023-09-13" version="1">MKTFSIVLAAGLSATAVAQNDAAYLSSVAASVSALVASLSANVVAQTSAAGSGSPADSSRNSAAYAAATSAMGAQSSIIDAALSSVYVAQSIASAQIASITGQAATATGAARSSLAAAGSSASEVLASASNAAGAVSSAGVSGMSGMSTGTTTRPSGTGAAQSGSSTGSSEALAAATHAPMIAAGAVGAVGMAVLAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE70</accession>
    <name>A0A9Q8PE70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Non-reducing polyketide synthase CTB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11407</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765204.1">
        <property type="nucleotide sequence ID" value="XM_047910555.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991285"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11407"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF40">
        <property type="entry name" value="NORSOLORINIC ACID SYNTHASE STCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="416"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1337"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1702"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1823"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1337"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1499"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1668"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1899"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1670"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1899"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1909"/>
            <end position="1925"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1368"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1559"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="2239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2239" mass="241062" checksum="2C393B71F11B1C7C" modified="2023-09-13" version="1" fragment="single">PHERGTNHSPWATMTGNHALQVYVFGDQIFNVADLLQSLIQENEDTVVSDFIGRASNTLKYEVAQLSPEQQAACPRFGRLADLVPHYKNGTLNPALVQALVCTAHLGSFVRDHSSGGQAFPPPNESCVAGLCTGALSAPAVSCAWSVASLLPLALRTISVALHLGAIAWEVGARLSPGTEPVIGADGKGAVQKFPSWTAAIAGLSKDEVQEITARFSKDLELPAPAVPYVSAVVGPAHLSVTAPPHVLARFLAAVKSTANASTAPLRISAPYHAAHLYNDHDVAGVVEAGIHRVAIDEIRARIPIISASAPRQEGTYSAQNQKKGGASFSVALCQAAHDCLTRRIGVDKLAARIAAHVSACAAGDVDFCLTAVTGGERLSPTVRSLLSVPRIEDDVRPKRSILPRLPTGAHAPSAQTPIAILAASGRFPHAEDMAEYWGVLARGEDAHELVPPTRWNAAAHVSDDPKLKNGSGSGFGCWLHNAGLVDTTFFNMSPREAPQVEPKQRLALLTAAEALDCAGIVPNRTPSTEKTRVGVYFGSTANDWMETNSAQNIDAYFIPGGNRAFMAGRINYHFKFSGPSYTIDTACSSSFAALHMACNALWKGEIDTAIVGGSNILTNPDMHAGLDKGHFLSRTGPCKTFDDGADGYCRGEAVVTIILKRLPDARVDKDPIEACILGIATNHNAEAESITRPHVGAQKQLFERLLVETGVDANNISYVEMHGTGTQAGDAGETTSVVETLSPLSAQGVSTRPASRPLHIGAAKANIGHGGAAAGVTSLAKVLLMMKNNKIPPHIGIKTKINHKLPDLLPRNTYIAKSLTSWNRPTNGKRRVLLNNFSAAGGNTAMILEDAPLPHIVNDVDPRSHHAVTISAKTPESMLSNLRNMIQWMKAQQSSDQLLSRLSYTTTARRQHHRHRISVIGSQVSQIQIALEDHLARREAGEKSLPVPPKAPSFVFAFTGQGSPYAGMGAELYAHFTPFKADIHRYDKLCTQMELPSIRPLFEQKDAFDQATPTQLQLMHVCLQMALSKLWRSFGAEPTAVVGHSLGEYAALYTAGVLSQADVIHLVGKRAQLMEHHLAPGTHAMLVVKADEAHVLSTLHEELGRECEISCRNGPANVVIGGTTTQMKEAREALERRDVRCQYLDTPFAFHTSQVDPILKHFASLSAGAELKDPSIPVISATYGRVLHSRADFEEGYFVEHCRKSVNMVDALAYAKKEGLLDGNIIGLEIGPAPVVTRMVKEVAGPSMFTFASMQKGQDTWKLMSQSMSQLYMLGVNLDWSRYHDDFPQCQQILELPAYGWNLKNYWIQYVHDWSLRKGEPPLMVTAPALETSALHTVVKNTLSQDGEIVVDADLNREDLHPMVPGHKVYGVPLCTPSVYADIALTIGDYIMQANSLGTQATTAVEVADMTIQSALVANDAGIQQLLRTTVKFDAKSKDAKISFSSVNADGKIIAQHAHCRISFTDIQRRKSALQTQAAHAETQMAALYAQTNQATNTYRFSKAMIYKMVGQLADFDPKYRGLIAITMNNDRLEATGTVSFKGIANEGKWGVNPAYLDALSQLGGFVMNANEGVDLDKELFVNHGWGNMTMFSKLDATKTYHSYVQMKEGGDKLWTGDVYLFDEAISLVGIVAGVALQGVPKRLMSYIVSAANKKVSGVSTVVEPQPPKVQQKRVPATQAAAPVSKPAPAVKTATTGKPATASLTMFAEAMKIVSEEVGVGVESLTDDFDFLEAGLDSLLSLVICSRLRDQLNIELESSDFLTASNVGGLKQILQKFAPAEEKAQPTTIEAPIAQPAPVLVPSNVTTAEAPPQIADAVAQQPANESAWAGAVTILAEESGLAENEIQDHLVLNELGVDSILSLVITSRLRDELEIDLPERALFEDCETVGDLRRQITGSSAESNAGQTTSSGTSTPPSEGSSYPESRHESVSTSISTILDTASEDDFSIVEKGRRSSTKPSAALAPAWSMYLQGSSKRAVETLFLFPDGCGAATSYLSLPTIASSTAVVAFNSPCMKKPEILGEHTLDEVVQSYVAGVRSRQPKGPYKLGGWSAGGILAYAVARALLDAGEEVASMTLIDSPPPNRGLDRLPDRFFDHCTSVGIFGNEMQRSDGTSNIPDWLMPHFKASIELLHDYHAPALPADKIKDMKVTVIWAGDCAFDGVKYAKLPPATTDSDEDTEGMKFLSEKRTDSGPGEWQGLFPGVKINAATIEGEHHFSMMRDQGAQELIRHVRESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF79</accession>
    <name>A0A9Q8PF79_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765860.1">
        <property type="nucleotide sequence ID" value="XM_047908585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF79"/>
    <dbReference type="GeneID" id="71989315"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09437"/>
    <dbReference type="OrthoDB" id="5386682at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="344" mass="38367" checksum="6C7F95002A14DCA5" modified="2023-09-13" version="1">METTDPRDRIFAVLELFRAGAKLNDIPDLLKPDYSKTAGAVFRDATRYALGEANSNTLLATISHRSNEELADNDFASWSLRWDRQYDPEQEAMQLGWAGAGLPQSASANDRRLVPNQVDDLSCLRLKARIIGEVNWCTNMIERRLLDYHVSQNIESVLARAEGVAYQQTFGVDDAVALSATTLTTGSLGDSHHRFENTDQRRFAFVQHLQYLKVHNTAPPLLLTETDPVSSNAPARFHRLLSSRAHRRRYFQLDTGYLGIGPEVLQIGDKLIVCTGAEHLYLLQLVGRAGTDFGSARDLGRHPLVSVQNSRCDKTGLPGPNIPLPSSRLPDQWITLVIMHVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFP9</accession>
    <name>A0A9Q8PFP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08986</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
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</entry>
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    <accession>A0A9Q8PGS2</accession>
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                <person name="Stergiopoulos I."/>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF18">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G12480)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="31930" checksum="8D31C0174A2B1883" modified="2023-09-13" version="1">MSTDATSKYSAQNLNDVSGLVAVVTGGGGGGTGLGLIIAKTLESNGAKVYITGRRQEKLDEAVKQAEHNNLIPIQGDTNSHADIQRAIDQITSEPGYIDILINNAGQTSFDSTPNARPKPTSDSPVSEIRDYYFNYRPHALWNQVLDTNVASVFTTSIAFLELLDAGNKRRASELPTSQILTIGSVGGLARSTDSFIYNASKAGVHHLMKNLGSFLAPHDIRTNVIAPGWFPSDMTVPVQKAWEHTEGVMPRSLVPGRRMGREEELSATVLYLCGRGGGYCNGNLERGGGWGGKRGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH47</accession>
    <name>A0A9Q8PH47_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766791.1">
        <property type="nucleotide sequence ID" value="XM_047908365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH47"/>
    <dbReference type="GeneID" id="71989095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09217"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="16040" checksum="7F0B599D0DF84992" modified="2023-09-13" version="1">MHITTSYTTCDPDGNVNTIHWIYWGHCLEILRQELVCRPSVHFYSMVWQEGQLMPFPDFHVQQTCVRWKDFTDMTTQRMTRDDEIKHKMKNIRRPEGAVQRYTPPEGWNVIEQNREWRHKMKEQEVDTKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHT0</accession>
    <name>A0A9Q8PHT0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767033.1">
        <property type="nucleotide sequence ID" value="XM_047911032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHT0"/>
    <dbReference type="GeneID" id="71991762"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11884"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="10976" checksum="5AEB1B718E1201B6" modified="2023-09-13" version="1">MEVAAPGTKVAVEGTLAEEERVPAWGEVEAAGRTTQVEVEAAGSTTQVEVEAADDTIPTQDRRLDENDTPVGKAVADFAVEVEVAGAVVFEVAVEVGHSTALQVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI13</accession>
    <name>A0A9Q8PI13_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="8">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 90 kDa subunit homolog</fullName>
            <shortName evidence="8">eIF3 p90</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF3, p90 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRT1</name>
        <name evidence="11" type="ORF">CLAFUR5_12481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI13"/>
    <dbReference type="OMA" id="LWGGPQF"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000419">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000235">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="39"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="739" mass="85572" checksum="6F574DCD54C4E40C" modified="2023-09-13" version="1">MAPSFEQLDPETEYEDDEEINFDDLKEQYETHMEEGLDTFIVIDGLPKVPEASKDKLVKFILRSLTKHGKTKEENVYMPMAEDGKMSEGFAFVEYETPAQAAAAVKALHGQPLDKKHTMAVNKLTDIERFGREGRIDEQYKAPEIPAFEEKEHLRWWLGDAEGRDQFVMYRGDNVGVFWNEKDGQPEPVVDRQHWTESFVQWSPKGTYLTSMHSQGVQLWGGPNWSRQKRFMHPGVNLVDFSPDERYMTTWSHRPMTIEEGNPVLSVEEDGKNYIIWDVATNKPLRSFQTLDMPGPATDPDGNPIKQKIQWPAFKWSADAKYVARMTPGQSVSVYELPSMRLMDKVSVKIEGIQDFEWCPATPQRHEQKEYEQLFCYWTPELGSNPAKVGLMSIPSKEIVRTRNLFNVSDAKLHWQSDSAFVCVKVDRHSKSKKSLATNLEIFRVREKGVPVEVVDSLKETVINFAWEPKGDRFVLITAGEVPAGSQVAPKTSVSFFCPEKAKNAVGNFKLIRTVDKKNNNAIHWSPAGRFVVVATVLNQQSFDLDFWDFDFEGEKEEKDKDLTANLQLMNTADHYGVTDIEWDPSGRYVATSASVWKHRMENGYHLYTFSGQTLREEPLEQFKQFTWRPRPDRLLSKEEMKQIRKNLRDYSRQFDEADNAKRSSADKAVIENRRRLLDEWLAWRERTVEELVEERRDYGLEELSEERKALVVEEDGDESKVVEEIFEEILEESEEIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJB5</accession>
    <name>A0A9Q8PJB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767889.1">
        <property type="nucleotide sequence ID" value="XM_047912137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJB5"/>
    <dbReference type="GeneID" id="71992867"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12989"/>
    <dbReference type="OrthoDB" id="4757095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="29"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="221" mass="24077" checksum="912FAE3942EBB278" modified="2023-09-13" version="1">MSTPAAPPANMAATTPQHPANSNASPRTSFLDLPLHVRNTIYHLALPRDEPLELQLSEQNGEKAISASSSSSPPTPPHRLPVALLATTHQINLEALPILYSTNTFTFTSARALITFATMIGSQAREHLHHIRLPTTQTNQELYKQCASRLRFSRHLASLEICGRGYEAGEHVTALKGLMVALKKGGRTDLEGLVGVVRFLPGGEGKGEFGEEDAERRMRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJQ6</accession>
    <name>A0A9Q8PJQ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768058.1">
        <property type="nucleotide sequence ID" value="XM_047912314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJQ6"/>
    <dbReference type="GeneID" id="71993044"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13166"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="303" mass="34677" checksum="88115B115E6255E9" modified="2023-09-13" version="1">MASSALCNAGGPSKTDTATEQRKGLLDLPAEIWSKIGKIVIADSNHLSATAFWESPKHPDFYHQPPIPRTCRILREEPLPQFYSTRVHIHCANFSRITVWLRRIGPELRRCLRGTVVLRSLFESEEHFRQRLMRTLGVELELDTTPTGLNPVIWHNTFVANSRRNGPVSLTSRPRSCQIGKHAIDNERRVCGGGLNVWKSTYHQPPITRTCRLLREELLPYFYSTKVLITCGADDEELGLWLRTIGPENRRAIVGIKRATFCPGGMDEESEYKENWGVELKIEMETLTNGIKQLQRMSRIRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKE7</accession>
    <name>A0A9Q8PKE7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-dependent monooxygenase terC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768486.1">
        <property type="nucleotide sequence ID" value="XM_047912091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKE7"/>
    <dbReference type="GeneID" id="71992821"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12943"/>
    <dbReference type="OMA" id="FRIHNRC"/>
    <dbReference type="OrthoDB" id="10016252at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="33"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="49437" checksum="47D4BF250FDF12DE" modified="2023-09-13" version="1">MPSKDRPFEKILIVGAGPSGLLLALLLALLLALLLALLLAQRNIPSLVLEAWPTLDTRLRATQYGVPATRIFRRAGLLPDFRAASIPKFPAICWRRVADGEKLIEIDMSLVEDEDDRMTVLQLGIIIQIMYRHCMERFGPDGSERKGLIEVRFEHRVVATGQDKNGKKAWVDVEIGGEKRRERVEVDYVVGCDGASSAVRRSLYGHEWLGQTWDCRFVVQDVFYDGFEKHGWDGGNYMVDNDHWGLIAKRGHGGLWRVTYGDSKVGLSDEEYLDRRPWHFKAMLPGNPDPHEYRIEQTNMYNIHNRCVPSFKGCLDVGGLADSYIGYYEGKASEEILQTYADVRRDIFLKYVDAMSIKNLDRVRKSDPWTVVETDKFFGIIKGLNDDQQALKEFLMKVSSIEYDFTQHYHGAEPGSMKSSNGSLEDRILPATITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLQ3</accession>
    <name>A0A9Q8PLQ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769212.1">
        <property type="nucleotide sequence ID" value="XM_047913493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLQ3"/>
    <dbReference type="GeneID" id="71994223"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14345"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040225721" evidence="2">
        <location>
            <begin position="19"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32168" checksum="D743B1E1CD659A65" modified="2023-09-13" version="1">MKPIVLLLLPVATALTQALPDDEMSHTLQWSRKSAPGCSAETASYGNDLVKVDCSFSRSSCLENCAENIDLAVTQLNQYYQERCNGERNLQEDTRKYKLLSSVQRIVDSYVNFNRLEMDLEAKVQVGTTLQGLQRNLTSLERQRGEWIDSCRRTTLPGRITPVGWHNGPNQESQGSAAIEKPSTTLPALPSASPKHIPTKAETAQAELIKMRYSVKDASDNIQAICAPNGNSTDTLTVQFEYSVCHTKVREGLDLLLNLEGNYDKALVPYEYFTFTDAEALSSQLGEVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM70</accession>
    <name>A0A9Q8PM70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769354.1">
        <property type="nucleotide sequence ID" value="XM_047913611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM70"/>
    <dbReference type="GeneID" id="71994341"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14463"/>
    <dbReference type="OMA" id="FDIVWRF"/>
    <dbReference type="OrthoDB" id="3535998at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="52075" checksum="3A92BB9E531FEB6D" modified="2023-09-13" version="1">MSSCRIERKRAHDREAQRASRAKTKAYIAHLEKTVADLTGSSGDNRANYLARHASKQAQEIDGLQGLVSKIRSLVQEASKGDGSSSSGSRPPRVKAEGSIVESMFGDGSADNPFSARGDSESASEDQWTNEGPGWTNTEVPNVLQREDPRPKAQPATASLPRNLNVLGVSVACEDTEDCTYVLRLNDAITKLEQTTDSLSGPQEDEDILVRAIVHGGDAAGRVHHFDIVWRFLRAYDEGLWYRAGQAGRLATLWQMRNNMLHKIQPKNQQQREISPFMAPTQNQLSCKKRAPIVDYFGWPAVRNHLLTQGIGKRTGKALIAFVESFRFVWPYDVRDTYKVNRSTGIYSFSESFNRSWNDLSCFRMLHNDLIPYYVHPSLAQAAPAPSATYHPSFEHQDSDESVDEEVVRSTDVVVPDLESMLQNDHPIEGWMQNFDMSMPNGASQYAMDRFTLSHEAGLNQWPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMC7</accession>
    <name>A0A9Q8PMC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease Hip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769447.1">
        <property type="nucleotide sequence ID" value="XM_047913336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMC7"/>
    <dbReference type="GeneID" id="71994066"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14188"/>
    <dbReference type="OMA" id="EVDGPYF"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="3">
        <location>
            <begin position="449"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="579" mass="64271" checksum="E5E4D7745311EF58" modified="2023-09-13" version="1">MEKGLPLAGGPPATAPSRTTAFTARKAIIGFILGYLVISTWLNHGPTFSRHSCHHKKHKGHNRYEGEKISWKPCGDVSGREVECSNITVPMDQFNATNSGNKTFSIPLVRLRGKNATQNVLLNPGGPGGSGAEFIFRRGKQLQDIVGEGFHLLSFDPRGINGSLPLASCYPTQEARLELSGVRDTEVIHDSPEVFAWTQNFVKACAETMDEHGAYINTPQVAADMNSILDAIGQENLWYWGFSYGTILGQTYASLFPERSERVIIDGVANNFVWYGDFFDTEQFTNTEDVLEGFFDECIKAGKNCSLTALAETKEDLHNIVFAKLAEIQQQPLSVYVNSTLYGTLTYPDLMFNGIFPILYGPSRWYGLAKNLADLLSGNATSTFLAYGNAPAWDFGGEANQFVTLNDGLSGPAYWPQDREELLKQIIPAANSSLFGPTENGDYYLRQQWIIPRTHNFSQPDSVSTLHPLLILSTSYDPICPLVSAKAANDAFVDSKIVEVEGYGHCSVAVASTCLAKHVRKFLYEGKLPDEYTKCEVDGSYFIVPEEDGKVVAQREFEDEEEGRIHLAQLEMARDWWTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMD9</accession>
    <name>A0A9Q8PMD9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769405.1">
        <property type="nucleotide sequence ID" value="XM_047913506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMD9"/>
    <dbReference type="GeneID" id="71994236"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14358"/>
    <dbReference type="OrthoDB" id="3650623at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="522" mass="57952" checksum="4F4DE1924BE28B44" modified="2023-09-13" version="1">MAASPPGITAKETDDRSLATATTESDLDALVGYKFPHACKEISACRICRDNFRDTACYASLRATGNAPLIARFLTYTQTLSKDEGRSVIAASRTGIDGRYRNICNEVSTKGDKIMARWSRFNAARRSTVLRAALPDNFPDDKWAHLCAYFTRGPQSPVSMRDKHRHKFLLPFLDLKDMASDPAKLLQLLEMRTQYPPAQHAWNDHQTTAFGRNSGMLAMRMSDVMISTQQASYGQSVGFEHEAFHRWETIGFPTAEILFEAQQHLYDFLAKVTAGILKGATGPATGCTAWLTAAAGAFASYASRNGQDDVGLFYVPVQHFKPLPTFDIQHIVPAYDTVASIVQAQYCSQQDDNNKWAAAAHELTQPLVERAKVWDTIEVLGACIQQVLRQQSSACEAGQTKLAGELEGAICHTHDTIRVFLEEEYPRLMRRVLLTDAVFDDVRRSNPRVMSVQDDKQKLGILQLQAFESQRLLWALMEIHNDSTSPYTPGAETALAYLEDMLAAGDVKSGTEAVRTPELGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMK1</accession>
    <name>A0A9Q8PMK1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MFS-type transporter pynF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769549.1">
        <property type="nucleotide sequence ID" value="XM_047913296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMK1"/>
    <dbReference type="GeneID" id="71994026"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14148"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF156">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="441" mass="47511" checksum="FE62EB7A78AAEC26" modified="2023-09-13" version="1">MNNELEDLTGRPVDTETQDIVADTRKQAWRALAGCAILQLPIWGIAMTFGIFQEAYTRSHVISGGSASGIIGTTMNGVMYLSMPLLFTALDRSWAQYRRSVAIAGIVISSLAFLVSSWSTQLWHLVLTQGVLAALGSTLLYSPTTLYLDEHFTAGKATVYGAILSSKNIVGSCCPLILTALLEKLGFRWTLRIWAAVVLCTGTIGIAIIPTKTSPSSQLTRGDRKVPWTFLRHKTIWIYSFANAVFSCGYGIPQTYLPSYARDVLKLSTLSSSLMITLFNAPGIISCVGFGLLSDKAKVSSTTNTFISAAGTSLSAFLLWGLSSNRIEGVLIAFSLLCGFFAGGYSSTWGGWIKDLEQEAVARNEAIDTGMLYGLFNGARGVGYVISGVAGVELLQVGSVQENMRWGYGTKYGALILFTGVSAVVGGWSVLWRYHSRPSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMP8</accession>
    <name>A0A9Q8PMP8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769631.1">
        <property type="nucleotide sequence ID" value="XM_047913508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMP8"/>
    <dbReference type="GeneID" id="71994238"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14360"/>
    <dbReference type="OMA" id="AINCWAS"/>
    <dbReference type="OrthoDB" id="2125396at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="49206" checksum="FD9D6C4C899E37EE" modified="2023-09-13" version="1">MALDMQSNWTVRMEKNLDYVTSGGRKNNDDVSNDHQPPKVDEKPRVWTSPAVYLPDEVIIQILEYVSHFKESQYTLASCCRLSGQWYSAAVPMLYASPHLYGKNFDPFVQTVVPSKNLHVRKSILAKLVKVLDMRGLVHQGSKSTTARLLGRTKENLEAFVAPVATFGDNCLAPLSKCPNLRLLDLAMVSESPSLSRLLQTVSHIQSLTTFRLPRSAGFHGQVTPGSVTWPPRLENLSLSGGIDAHFMHGIVALPPTLRSLTIEHCPAAKGFALMHLLRTAVQPLPELEILRLANLPRLGTTALDSVLVVLPGLTKLSVSVDYISPILFDLDVGSHKEAVEYIPCLPHSASLPTRHRWTPGRVCDLRTLELTNSGNPGIEDKISPIDVMIALDEGTLPHLRQVRVAKSLLWHTSSTADDLDALSDALKESAVQQGDAESAMGVWTFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMS6</accession>
    <name>A0A9Q8PMS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090176">
        <property type="protein sequence ID" value="UJO25416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769782.1">
        <property type="nucleotide sequence ID" value="XM_047913792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMS6"/>
    <dbReference type="GeneID" id="71994522"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14644"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="101" mass="11575" checksum="E7547B80ADF40D72" modified="2023-09-13" version="1">MSSSRYAPATSSSLALIERQLERSQRLVDRIARLYASPIADPLDIAQLADEVFHFYDNFYNYTIDLLIGRADPVTREMTFPNPLDLLDTRSDLELLRAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQH5</accession>
    <name>A0A9Q8UQH5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Ribokinase</fullName>
            <shortName evidence="12">RK</shortName>
            <ecNumber evidence="2 12">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_07612</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="2 12"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763170.1">
        <property type="nucleotide sequence ID" value="XM_047906760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQH5"/>
    <dbReference type="GeneID" id="71987490"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07612"/>
    <dbReference type="OMA" id="DIVLIQQ"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="14">
        <location>
            <begin position="7"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="43"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="232"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
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            <dbReference type="ARBA" id="ARBA00005380"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO18804.1"/>
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    </evidence>
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    <sequence length="333" mass="35186" checksum="B29D70F34FA267E3" modified="2023-09-13" version="1">MAITTKTVSVIGSLNIDVVTRTSRVPAAGETLAAISFDTGFGGKGANQAVAAARLAGEDVNVRMVGQVGDDNFGKDWFEVLEKEGIDSTGVRKLKDGKTGVANIIVEEETGENRILFTANANYAFPETQDPSWDLVSEGQIVVFQLELPLNVVLHNLALAHSAGKRVILNPAPASPLPQSAYANIDTLILNETESSILAGPSHQPPDQSPSSLLELSKHFLSLGVRDTVIITLGAKGLVYATASGKDGHMAAYKAKVVDTTAAGDTFVGAYAVQRAKGLSQDFDYGAALQFATLAASKTVERKGAMAAIPYLKELQVEVMRENGTLGMEDVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8UQH7_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07390</name>
    </gene>
    <organism evidence="3 4">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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    <reference evidence="3" key="2">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        <source>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987268"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07390"/>
    <dbReference type="OrthoDB" id="3650798at2759"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20300" checksum="E96230C563581C92" modified="2023-09-13" version="1">MLITADRGTMRKDRESQDKPKGVNATHKLRLLRPRAYRSLCGTIGISLWHGPPRPGNIRSRVATSVSASMVGFIWSHGDEQNIKQRAHSPAPAEHSPEKAVEVFATVELIEDILLRLNALDILRAMQVSRFMRDTVIGSSKLLKHIGLSPNLEAHFSSPLWPGSEKSRIIPRSLPVLSRHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URG0</accession>
    <name>A0A9Q8URG0_PASFU</name>
    <protein>
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    </protein>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909822.1"/>
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    <dbReference type="GeneID" id="71990552"/>
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    <dbReference type="OMA" id="WNQTIST"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040173380" evidence="2">
        <location>
            <begin position="21"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="200" mass="20646" checksum="DDAC36132B58CA10" modified="2023-09-13" version="1">MRSSIPTILATAYFTLGATALPNPRPAATYQVVDVGGPSSSINSPPAETLPPTSTSTSKPATVTVTASPSQASITETQSTTITVPNTAMPAFSYTVTMSPLPVIITNVSPSTVTETTAEATETVYNTVPEPAYATAVQSSSSSSSSSSIYTSTFKGAFTSHGLWNQTMTTTTYPTAGTAVYARYPTNVPCPDEDAGKSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URI3</accession>
    <name>A0A9Q8URI3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_10714</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764117.1">
        <property type="nucleotide sequence ID" value="XM_047909862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URI3"/>
    <dbReference type="GeneID" id="71990592"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10714"/>
    <dbReference type="OMA" id="KGPEQAN"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040206177" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="18"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="130"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO19751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="21843" checksum="F649CA2D9B2BD6EC" modified="2023-09-13" version="1">MKSTLALALSIATLASAQVQDLPKCAVQCFAKALASTTCAATDAHCACTTGAADFIKVAIPCLCEAGCSVEELKRIETSTNNLCAAALSAKGEDYTPATLDPKICQAVETGTTSSASCASVSLTSVTGTATATQTASVTETATATATDTASTTATATAAETAAPESTGGASGNGFMGDTMENGEREGKRQIGTEKEDVAYKINSGEEGKGKLPIRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US08</accession>
    <name>A0A9Q8US08_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SET domain and MYND-type zinc finger protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10448</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764730.1">
        <property type="nucleotide sequence ID" value="XM_047909596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US08"/>
    <dbReference type="GeneID" id="71990326"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10448"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="73"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="61965" checksum="FC6A0307F35683F3" modified="2023-09-13" version="1">MDVLVKTSDITGGSRGLFAKKDFAAGDLILSLDRPYVAELDIERLKDTCAWCLQRGATDDFERQRRAALGNFTNSIIDTKACTGCKRVRYCSKSCQSKAWKREHKYECKVLAPDNRPDLPHGVRAVVKLLGRMKNDPEGKDEALLDILQFWPAGVADKSALDEFKKQNQHRYEDFGMLAYGSWKYAGEPNMGGTESEAIAKGLFFNVMSNTVQLSNPLDDTSLGMGFDPIMCSANHSCDPNAAALFNQPRQILRALKPIKKGEELFMKYTDVSNPLCVRQAELKGYYFFTCQCPRCKQGPIFAEDTFLKPPEQLKSEFATIADSVLIPWHEKSLAAFSVPSSDPTAGRRMAALQAEAFSVSGLSEDLNRGNTDAGEDEVKDALKLCLNSEMWSYTRQPVPHLIRQLLVIYLSQGRMYAAWRLGAFRHFLIAPDLYPQPFYPDRVIDCWLMATVTNSLCNPNIPSHKEIFEQCLQSGFDLRIVYFGFLLETREQIEKSYGRDSPFGRLVETVYQQTVQNTDISLTQIKEKIKENWPKLEAVAKNVDVLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USY4</accession>
    <name>A0A9Q8USY4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765647.1">
        <property type="nucleotide sequence ID" value="XM_047910074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USY4"/>
    <dbReference type="GeneID" id="71990804"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10926"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="51" mass="5745" checksum="BD39AECAB766FB5C" modified="2023-09-13" version="1">MKIVGMYSAEQIRALKQENSRLQQQNSGLEAELQRSLERASKGHSSLSVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTZ6</accession>
    <name>A0A9Q8UTZ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Extracellular metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08936</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766711.1">
        <property type="nucleotide sequence ID" value="XM_047908084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTZ6"/>
    <dbReference type="GeneID" id="71988814"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08936"/>
    <dbReference type="OMA" id="ATWANDP"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="9">
        <location>
            <begin position="136"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="29530" checksum="E1BA597CD3FC7E70" modified="2023-09-13" version="1">MKFIPLTAAAASLAYAEEYVRCKTEPTAEKISMLNEAASNASAASSEALFSIAALRNVDTYVHVVTTSAKAGRYSQAQVNEQISAMNNAYAPLNVAFNLVDTDFTTNNAWAAAGDSSSAELAMKRALHQGSYADLNLYFLSDLGGGLLGFCYFPEASPSSQDLILDGCVNLADSLPNGSATNYDEGATAIHETGHWFGLYHVFQGSSCSGSGDFVSDTPIQRTATSGCPSRQDSCPNAAGVDSIHNWMDYSYDACMYEFTAGQVTRAAGLYDQLRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUK3</accession>
    <name>A0A9Q8UUK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_12273"/>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="31207" checksum="48C1BADAB16BAFB7" modified="2023-09-13" version="1">MKRRPKRHYQAMRKSNTASPKSSPIARTNKVIPRNERDDNRHIFPFFDLPAELRDEIYDNCTSDHETILSSHVRMITKQLGYKHLLLISRQFTHEHRARLPRKKTVILTKMKQNLALDLTSFAIPSHLAQASDIEIYMLVDTTSPEAAIADLTAQQQSLYKFFPQLRPDQSLTVRMIFDCTLDSESTWRRHWATIFHNYAEDMKRRGVTRELVIHVDLLKGVTVEDLAPMYRWVYPLNIVEILVPEGGEAEYETSVQSASEDVEDRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUV4</accession>
    <name>A0A9Q8UUV4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane fusion mating protein FIG1</fullName>
        </recommendedName>
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    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12617</name>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71992495"/>
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        <property type="component" value="Chromosome 11"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <location>
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            <end position="40"/>
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    </feature>
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        <location>
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            <end position="161"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="207"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29105" checksum="E72A07695044EB54" modified="2023-09-13" version="1">MPNVRFAVGIQRLIPFLGYHHVLMILIALAIVLLSLLLAGCSSSSPTIPDIFLISFYYEQYTPTYDPTQVNPGVAAALGNIVGRADLEVRVGYFGLCVQPDGGSYLCSNNATLLAEQISIDQDPLNLIWVANTFKNSVVFPYLIIVAIVLAFVTFLLLATFPGWHEEHDARTGSDIDIKPFPSRPVSQVALALIFIASIFVLVSVLWQHTASVAAAQIAQDFGNGNVKSGVGTSAMVLGWFGFSLLIIVTVGLLVMILSIHLLDKLTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUW0</accession>
    <name>A0A9Q8UUW0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12333</name>
    </gene>
    <organism evidence="10 11">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
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        <property type="protein sequence ID" value="UJO23172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUW0"/>
    <dbReference type="GeneID" id="71992211"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12333"/>
    <dbReference type="OMA" id="ARAHFHI"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
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    </dbReference>
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        <property type="entry name" value="NaCa_Exmemb"/>
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    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
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        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
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        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
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        <location>
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            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="1053"/>
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            <end position="1088"/>
        </location>
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            <begin position="114"/>
            <end position="253"/>
        </location>
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            <end position="1080"/>
        </location>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
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        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="7">
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            <end position="640"/>
        </location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1093" mass="120233" checksum="F390B5037F962EB3" modified="2023-09-13" version="1">MPPTRNRDGRLRFRAARAFYLTLFIGTCFAAYSLFSHSDGPAALPQQSLHRRSLETPVTTTGEDDCRRVHQAQDECAFIRAHCPDDEGGFTAYLELYYCKLPHAKPVAFIVLISWLGLLFSTIGIAASDFFCIDLSTIAGILGMSESMAGVTFLAFGNGSPDVFSTFAAMSTDSGSLAVGELFGAAGFITAVVAGSMALIRPFHVAKKSFVRDVGFFLVAAAFSMVFLWDGKLRFWECAAMVAYYIFYVAFVVAWHWWIGRRRRQREKNAAVRGHFIPPEEEEHEPYHDDPDEAPDNSRPTLSRGASREDWTVLEGGVADPHEENQNEDEEEEARDKWMSELASNMRLTRPTARSRRNTINPVRPSLVGALEFQAVMKSLNKSRNFQTIPLDSRRYSDDPTFTTLQQQDQMSSISDPAARPPYEVHITDESSPQLERPEPELLPYSAPPGRVRAVSANDAAALGINRRLHHFPSLTPIQSEDNLIEASSDEGQHSRDRSRSTSRLAVPRIGGAPQLASPTIMVEPSTPRQATQPMEGTRTPGSSHSVDLLAPPDQHGNVPFNRPHSDHFVPQVPSRQGTDSPKNSPRLVPRAKQLPKIVIPQRSGSPSSSRATSPFPTYRDFPSPSVTASTRSPSTRPPSVYLPAPGLASPESLPVDQAAERETPRRPTKLNKLWPRILPPPGVIISTLLPTIYHWHEKTWWEKLLGFVAAPSVFLLTVTLPVVEQERENDSTSPSQTPAHVDSFDSMKSRSKSIRGAPGMSPGQVRGLVPEFVLDPADAHAGSHRHTLTPGDVTHGPGGTATMAAEAEQQHREQYHDNPNKHASISAEPSALENSLLDETENPHELWNRWLTIIQLFLAPIFIVLALYIQSPADLSPHWLIRPILICLLVSVVLLIPLLLTTTPTHRPEVYRIILSFAGFVVAIAWISAVASQVVGALKALAVILNMSHAIMGLTIFAVGNSLGDLVADVTVAKLGYPVMALSACFGGPMLNILLGIGLSGSYILFTRAEHKLDKHPGKGLKFHSYHIEVSKTLIVSGITLLITLCGLMILVPLNKWVLSRKIGWALIALWTISTIFNVVIEVTGFLGEMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVF5</accession>
    <name>A0A9Q8UVF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768287.1">
        <property type="nucleotide sequence ID" value="XM_047912103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVF5"/>
    <dbReference type="GeneID" id="71992833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12955"/>
    <dbReference type="OrthoDB" id="2107880at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061671">
        <property type="term" value="C:Cbp3p-Cbp6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037653">
        <property type="entry name" value="Cbp6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250:SF1">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="18860" checksum="729837F673792F76" modified="2023-09-13" version="1">MPGDVLQPACVPDARPSPKVVHPPSMTMPLNIHVQTSALRYTYTPSQLSYIMSRQTIAAHYARLLTRWPQDVLRPEKSFTKIFQPRVQTPPAPCRDEEKEVNAAYLLLDNAFTKQFRLQQRLLKPDSNPEHYTALKQELEELPHRTWFGNLKRRLTNMVRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVX9</accession>
    <name>A0A9Q8UVX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sugar transporter STL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_13821</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768812.1">
        <property type="nucleotide sequence ID" value="XM_047912969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVX9"/>
    <dbReference type="GeneID" id="71993699"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13821"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="23"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO24446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="547" mass="60585" checksum="EC4BF644ACBECB0C" modified="2023-09-13" version="1">MAIFSHKGMLGGHISGKALQTGVCITAASGFLLFGYDQGIMSGIITEPAFLEQFPQMDPDNKSGAIQALVVAIYEVGCLIGSFLIVFVGDKLGRRKSVLIGTVIMLIGTALQSTAFTLGHMIVGRIVTGVGNGMNTSSIPVWQSEMAPPTIRGFLVLFEGALITGGICLSYWVNYGFWFVTQYDSFQWRFPIALQAVFGLLLILGVLLYPESPRWLIKTGKQENVDAARTITAVLEDKPADDPTLIADIAEMQRINEITSSTKLKPKELLTNGKEMNLWRLSAACLAQAFQQLGGLNLVTYYATTVFEDSLGFDPELSRLMTGCLGTEFFISALIALFVVDKLGRRMLMLWGAFGMGTSLLIIGACLSKATDTYKAPAYAATVFIFVYNTCFAIGWLGVTWLYPAEVTPIRIRAEANGFSTCSNWLINYGVVQLAPIMINKIGWQTYFVFMCFNYFHIPVVYWFFPETNGYKLEAMDAIFETAHEKGENPVWTERRVRKGKETIDLEKHEHPQAGSDSDPEGTVRGAEIEKEEIADDEEYKRRSNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVY7</accession>
    <name>A0A9Q8UVY7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768824.1">
        <property type="nucleotide sequence ID" value="XM_047912703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVY7"/>
    <dbReference type="GeneID" id="71993433"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13555"/>
    <dbReference type="OrthoDB" id="3650836at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="78"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="346" mass="39969" checksum="33742E7F41728A84" modified="2023-09-13" version="1">MISVPIDRHRDDAYRDEDEQEAAEAERLEEIEYQQGLEQRLDDPREDLKFALHHLATPIEVFREQDIAYYHVKPAFPFMDLPAELRERIYKMTLRLPASGVQVIPPENGYQTRMRVFTRNHESQNTVDLALTDRRRRNTLTTFTIRAFLGLLLTCRKIYEEAMSLFYKDNNFVFFGLFALSRGLRALAPTRRNHIEHVSLNWCADLYYSSGDGENALKILSQMPYLRRLDVQVSESDWTSYFSKIDNKPFTVTRIPGFTAMQKIRGLKTVKFYGDCDGVKSVLEPLLMQPLAETAEKKRKAAMEPKQEATKVGRKRKVEVEVHEAVDVDAPSKTRSMARGLNAKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW04</accession>
    <name>A0A9Q8UW04_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768841.1">
        <property type="nucleotide sequence ID" value="XM_047912640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW04"/>
    <dbReference type="GeneID" id="71993370"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13492"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="142" mass="15629" checksum="A996227052962EB4" modified="2023-09-13" version="1">MAAITSPEIQAVIRNVNAKALALGYDIMADSNKPDLSEAIVDYINVTIVDVAGRPSPASPTFTSTSLVHFFRRISEIYFVRFASLATTSILSSDLPIRHWHLLEKPMDMQCPPGALPQIDGFCQSSFAVRLKRLEGQGQFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWG0</accession>
    <name>A0A9Q8UWG0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_14317</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769380.1">
        <property type="nucleotide sequence ID" value="XM_047913465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWG0"/>
    <dbReference type="GeneID" id="71994195"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14317"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="95"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="353"/>
            <end position="357"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="396"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="494"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO25014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="586" mass="67457" checksum="823225670A3D4B03" modified="2023-09-13" version="1">MSLLLRLSRSFRGPIIAISRPCLLASIPQHRSTFHTSPASNMPPKKHARSASHEEGHPELKHPSTKRAKEIDQHTPYEELVSLLDANDASAKPKNVLHWFRSKDLRLEDNRALHAASQKAKEGDGNLICLYLHSPKDLTWHGTSPARLDFILETLRLMKQQLEKLNIPLHIATVESRSVKTNTVLDFAETYDITHIYANMEYEVDELRRDIDLSNAVVKNDYYDISFEVLHDQTVITPLTLTTGAGSPMKVFTPYHKAWLAETKSEPALFEDLVPGPEANGDGAREELKRLFGGDLPGMPEGKSFEQYEEDRERLRALWPAGHDAGMKRLDDFLEKKVKNYAAHRSEPALDPSSRLSPYFSSGVVSVREVLKRTKEFNNGKHFDAGDRGVDSWVREIVFREFYRHIMVVIPHNSMNLPQNLKFDFVEWEDDEEGYRKWEEGRTGVPLVDAGMRQLSSEAYMHNRLRMNTSSYLRANMLIDYRRGERYFAETLIDWDLSNNTQGWEPSYTIFNPVVQAEKCDPNGDYIRKWVPELKDVKGKAVFDPFNRLSQGEFEKLGYPEPHVEFRESQTRAKERYKRDLADADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L567</accession>
    <name>A0A9Q8L567_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_01832</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755461.1">
        <property type="nucleotide sequence ID" value="XM_047900980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L567"/>
    <dbReference type="GeneID" id="71981710"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01832"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="185"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="451" mass="51292" checksum="408183094C9A5E12" modified="2023-09-13" version="1">MQLSNSASCMPRKASAAVVATLFLIFLYLYGSPRFSSSLRHDAPLPFSTERPLACRQLPGAEDVVVVIKTGSTEFQDKFVVHINTTLTCYPRSLVFSDYAETYEGIQIIDALESIDDKIKQNNPDFDLWRRLQDGGRSVLLPEELSGPVSASHASKYGNTGNPGWKLDKWKFLPMATRTLQEYPDAKWYLFVEVDTLIFWQTLLNYLPELNSDDPIYMGSMIMLQTTHFAHGGTGFVLSRPALEMMVEKYQAERAFWDQYVENTWAGDAVLGAVLREVGAHFINARAIFQGEEIGNVPYERDDWWCTPTVSYHHLAPVVVEDMWRFEQAWIAGTKGNSSKILRHQDVFDEYILPRVMSQPSTGTADWTNNAGMDQGPVESLDACRSICMQHTKCLQFMLDEQTRCKTSEVPRLGEMAKGVSSGWLVDRIKSWRESKSTCSDRRKWIVDRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5K3</accession>
    <name>A0A9Q8L5K3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division cycle-related protein res2/pct1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755520.1">
        <property type="nucleotide sequence ID" value="XM_047900908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5K3"/>
    <dbReference type="GeneID" id="71981638"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01760"/>
    <dbReference type="OMA" id="NGCYRLA"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0183">Conidiation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="8">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="374"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="512"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="697" mass="77915" checksum="AE72DBBB182F75C0" modified="2023-09-13" version="1">MSRSNLIYSATYSNVPVYEFNVDGNHVMRRRSDDWINATHILKVADYDKPARTRILEREVQKGVHEKVQGGYGKYQGTWIPLDSGRELAAKNGVLEKLRPMFDFVPGDRSPPPAPKHATATSSKPRQPRAPAQPKRQPGKRARDSPADSPAKRSKVTAQPDYDQMDVSVHDGETPDNVTIASESFDDYDNSHFTGSRKRRRLEETMSQADREHQLWADELLDYFMLQDNPMDSLPQAPLPPASADLDRSIDDKGHTALHWASAMGDIEVVKDLLRRGANIDVQARNGETPLMRAAIFTNNYDRQNMDRLAGLLMRTVNMQNWYGETVFHHIAQSTQRKSKYGCARYYMDSILNRMADILSPDGIVRILDTPDQNGDTAITIAARNGARKCVRSLISRGASTEIPNQFGETADQLIVQLNQRRQERQSNRHMSSSPYQFDTSQSTIAVGASQSHMNGLDGNIPIDPLLVSQQSLAGGGGSQNIDPSDSYRSDDALALISSVMPTIFNKARTLALSIDTEVAEKEAELAEAERVAAARRQEIELLKRQAEELRAEEEHVGSGAVDGDDALLTELEELMQECEGLTAEEQDTALKELILQEEAEADENMQNEDLLIGTEDDSLEHRMELVQELHGLVQQRKDLFKTIVQNLSNAGIDEKQHEYKRLITGALDVREEDVEGMLPEIVAELEDWQMEVGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5S9</accession>
    <name>A0A9Q8L5S9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biofilm regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755761.1">
        <property type="nucleotide sequence ID" value="XM_047900210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5S9"/>
    <dbReference type="GeneID" id="71980940"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01062"/>
    <dbReference type="OMA" id="HYATRAH"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="457"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="515" mass="55447" checksum="3D0A96DC0647E334" modified="2023-09-13" version="1">MDRRPQLPALSYLDVDQVKREEDAYQNHNAGTPQSLSNTSAAPSPTYQYPSGPPPPYSHAHGVAPPAQQHANAWTGTQSGVHTPPESRRTSEHEKEAAKQGPRQSLPSISEALGVDSQTAFASAPAAPAPLQSTHLPLPASGPPTSPSASSRRSYPMEPPPGHANSFANSSSYSQYPQYRSEPAQRQSYPPPAEATRAPAAYPPVQDSKPVLHQPSAQPQSRSPPPPTSFSRPLESSPASEHPPNPSAGSMAPPSSVPYGYTPYPPRYADPTPPASTSSGPIYQPSTVYGTPQTTSSSGWKAENTARFDSRQPEQANYGDNVKRHLDFYDLGQALNEISSVSGHLGDFARRYGDRMHQTQRVGPSPSTLPGIVEVDDMVAKSRAQLDSLLKIRDVVLAQQAVYEQQAADQRLQHKAFSEGPQPQPDLHAPEMDESKAGGFAGVDTKKRRGRAAPPGRCHSCNRAETPEWRRGPDGARTLCNACGLHYAKLTRKNNGANKNTSVGNSNLRPKENMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L628</accession>
    <name>A0A9Q8L628_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Helicase SEN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_01496</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755852.1">
        <property type="nucleotide sequence ID" value="XM_047900644.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71981374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01496"/>
    <dbReference type="OMA" id="GCIKCIM"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001152">
        <property type="entry name" value="tRNA-splicing endonuclease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024481">
        <property type="entry name" value="Helicase_Sen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12726">
        <property type="entry name" value="SEN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="11">
        <location>
            <begin position="1290"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="869"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1451"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1847"/>
            <end position="2043"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="947"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1875"/>
            <end position="1891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1892"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1902"/>
            <end position="1928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1935"/>
            <end position="1951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1952"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1988"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2022"/>
            <end position="2033"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="1311"/>
            <end position="1318"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2043" mass="228650" checksum="AC47091F887ED380" modified="2023-09-13" version="1">MEFVQKLEALTNLDAGIHWFCPRTTDDETGVYYIDDIDSSEPESESEKATRLSKLKEATQRKEDALSATQIIAFDGDDAMPYQTKLKTHLKTQLTRCDICIREFHRSRAWLKSQLEAEYAADEVRTFLDKYDGMNNERITTGLDQATEALLDLEPSKRKITSAGEAGMYAMFEALQCRPFLYSEELLSQHFDKPFRLAQANRKFSLPGVAPGTVAFLYSMNAERFAWAERNITRLKRKILPSEFESSVKPFMEGAAGRVHVVNLDARFLPVFWRATRMLLEKFDKELITNYLRAMDVNIYTLSLEHFQVQQDHVLDIFGCYGILLELAPNDFWEAMGAVSPSNVLDVAFTTKPNQLETLFTSKQESGRDPQAYLALQVKWLDAFVKSIKASNLVPPLRTLLQLCLKRYQADQYSHFASTAMWERGLCCLQEAIRILTRDLDGGPAYTHLIEAVSRDYIGDILAQLEGIEKKEELQITKDQNSALDIIQNLLALDVRSLSRDRRMIESKRELDHEIGVASLNIWKMSMRHIKPGHSSFVMSIIRGMNGLLSLDLLPPKIVKAATKTAESWNNALTRILGYVATDLLDRLDSFNHEQLLDLIALPEAMNGIVLLLFNGNEMIHANALTLLKTFSGEDSRRESIMHLLKAYYSNAMSAFGLSLKAVINAHIFGPCSTLLKILRDVFSCLCDDQDGLLRTKTISGETELTALRILWVHTWSFLEMVFSRTEAWSSLGYDKAMMQLFCRDTMDLAEFVFDQYAVIASTMEGGSIQVSSATGKQLLQQSNKAFGHITKWLRLRDEYLISRCVSITGKMLTRFQEVNIRISAENSTWLQDVITSSSTSKYAKVKNKLTMNNKAELQQALERHLGESLSASDLSETEGPKRTKQGSLADWAASAGDRSGSSTPVSASRPEGVIDLDTWTSAAEKRKAEERKPMQKVPTLAFQKAAMKKQEEANDFLLKRRQAKEEADRKRQEVIAKAKGLGAGSGVAGIGNYGADHGTEGQTVMVNDDDLESDDDDDDLDDDLFGTVDKPKKQQRPGLDFSGATGLKPEVKSGPTRIQRTARSVKDMRARIKPALGPLYQTMLSWDFFHTDHYPPGSSPQDFRAVENSFRDPISYQATFEPLLTLEAWQGMVRAREENQSKPYELKVQNRSNVDQFIEFSSIIGHQENREVELRESDIVLLSTSKKPADDSTAAHCFARVQKTKFTKAHMEIVYQMMPASALAPKLTMQSIIYGLKVTTIVPLERQYGALKALQYYDLCNQIVRAKPSSRYEFSEKQITSMQGVYGLNRAQSEAVNAALDNEGFSLIQGPPGSGKTKTITAIVGGLLTQSLSNGPAGATRITVPKGNNVNSGSDAPVKKLLVCAPSNAAVDELCVRLMAGIKTKQGVSRNINVVRIGKSDNISAQVAEVTLENLVQKKLGGTQQDSKQHEKDQQIFEEHKQVSAQLREFYQRRDEDDSGDKKMQPAGRKRLEDDINRVKRQKAMLGTRIDSLKDQRRDAGREQELNKRRVQQTVLEEAHVICATLSGSGHDMFQNLTIEFESVIIDEAAQCVEMESLIPLKYGCIKCIMVGDPNQLPPTVFSKEAQKFQYEQSLFVRMQNNFPNQVHLLDTQYRMHPDISFFPSETFYDSKLMDGPNMAEQRKQPWHASALLAPYRFFDVAGQQQTSAKSFINLAEIDIAMMLYDRLRADFNDLDWNNKIGIITPYRSQLKELRRRFLNKYGEGIKDFIEFNTTDAFQGRECEIIIFSCVRASPAGGIGFLQDIRRMNVGLTRAKSSLWVLGNSESLSRGRYWKLLVDDAKARDLHTAGHGLKGMLKRPSSDFPAQASAVPTRSMLEINNHVSQMGAEVEGSRNDATPNSKELPSYTGKRKHSADEGDNKSDKPFKQSRDSTPVTSARNGTDRMDGVTIKAEDRIRGMKQERDHTTAAKSITEAEDDMDVDMVDADEAELDKAGDDMKKDTPDSLVKNPRRSATPANSAVDRNGAKSASGSRAGTPSSTTEDSKNGIAGQGNAKPAGGIAPPRKAFKRAAPNVFAPKAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Y2</accession>
    <name>A0A9Q8L6Y2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar morphogenesis protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00628</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VAM6/VPS39 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756331.1">
        <property type="nucleotide sequence ID" value="XM_047899776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Y2"/>
    <dbReference type="GeneID" id="71980506"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00628"/>
    <dbReference type="OMA" id="EEYCNQV"/>
    <dbReference type="OrthoDB" id="5325112at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
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        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF49">
        <property type="entry name" value="VAM6_VPS39-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="7">
        <location>
            <begin position="18"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="4">
        <location>
            <begin position="753"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1089" mass="120521" checksum="452A08D31B338798" modified="2023-09-13" version="1">MLSAFKAQAVYELRQRDKSKAESLLAYGDRLLVGLSTGALRVCRVNAPGASPEQEGRSSSNSHGNANANANDGDGDGDAAPPSPSAAKSKVVEVLHEEDKFSKKPVQQLAIIKEANLLVSLSDAYVSLHHLQTFQLVERLERTKGAACFAVTSNVVKDAETKVPSLVSRLAVGSKRKVMCWTWQDMELAEDIVEINMEASLKSLNWTDGTRLMVGMDPGFSVLDITTQEVTPVTKSAPKTASSADLNNGELVGVRFGAVSSSGMGYMGMGSWVPKPMATPMTGDEVLLAKDVNTLFVNTEGKPLEKRQIPWAQAPEAIGYSYPYLLALNPPDKGTLQIRSPDTLSLLQTIQVPGAIVLHVPQPNISLAHAGKGFLVASDRTIWRMNALPYDTQIAELVEKQRFDEAISLLNLLEDTLIDDKAGRIREIMTQKAIVLFHQQKYRPALDLFTHAETSPDRVVALYPRSIAGDLSSIEEQPSEVGPEPDEAVEGRSEDAGKEAPSTPQKGMLGRLRGSARKAEPDAASIRSPARKDTDNMTVRTKAGPSKPQDKPLEGDDLKVAAHCLTSFLADARRRMPIYLNPDGSLKEDPPTLDCETGKPAFCNLLPQAIVDDLKAGLEIEWQAELLKVAKLVDTTIFRCYMLAKPGMAGSLFRVDNFCDPEVVQSALYESERYSDLIEFLHGKKLHRQSLEMLAKFGKNEAAAEVPEGMLGPERTVAYLKQLPPELVDLVLEFVRWPMDEKPEVGMEVFLADSDNAERLPRDKVLKFLSGIDPRLEAQYLEHIINELNDNTPDFHQQLVDAYLTELKQVDILEEERKQAKARLEAFLTRSRDYNKRKTFQQLPTDEPTFYEARAIVVSAMGNHKQALSIYVFQIKDYEMAEAYCNKLYAQEQADEQTCLLEGTTTHKKHFKSAPEDASDKNIFAILLGLYLRPPSGEEKRWPQALDLLSKHGPRLPASSTLDLMPDDLAVKELQDYFRGRIRNATSILREEMIVRSLEGVRRANTERTLLVGPDDSGHDKPLGKNRRVRIGEDDHCKVCLKRFGASAIRVYPDNEVIHYGCIGRSGNNRMREGGGRGLGALRSSAGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7V0</accession>
    <name>A0A9Q8L7V0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily multidrug transporter mdrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756838.1">
        <property type="nucleotide sequence ID" value="XM_047899476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7V0"/>
    <dbReference type="GeneID" id="71980206"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00328"/>
    <dbReference type="OrthoDB" id="5410178at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF157">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="575" mass="63169" checksum="3E47A2461F8C6A8A" modified="2023-09-13" version="1">MADHEHERDESPSGFSAGSNQDDRQRSPSGSSLATSISSASLQKSDKSIVHVPCYVKRELHLEGLQVDDYGVVRWQENSHAHPRQWSLGRKAYDSGLICFLEFFVTLISNTGSSIALEQTDFDIGRTTALVCFTSVYMIGQALGGLVFPPIAESFGGRTVYVTTTFGYAIFCLLIAAWPILPVVVICRFGSGFLSAMPAVVAVGSIENMWDVRARIWLIHLWIATAVLGLALGPPSGDFCEHFVVWMILSPIVLTVSRQWIFYIASAIAAVSTLLCMKMKESRPSQLLKQRVKIVARNMGFDGLSCDDTDSIPDFRTFVKASLSLPMRLFFTEPIVMLTSIMAATVYGVTYLFSEAFPVIYTEGWGFSHREASLVFIAIAAGLAFTFLPRLFDIRVTNGRRRADQVIEPEDKLFGFYVAAPVLAIGLWWFAATVPPLVRGITPWASIISVGLFGFAVVEFDAVLSGYLTDTYASYAGSANAPMAFLRAMFSAVFPLFGTQMFERLGANYALFILAVIATAYCAVAGLFGAYGKRIRQRSPFAERTWAVTVASQQAGRIATSLQEPEKCLDMGRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L886</accession>
    <name>A0A9Q8L886_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00136</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757092.1">
        <property type="nucleotide sequence ID" value="XM_047899284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L886"/>
    <dbReference type="GeneID" id="71980014"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00136"/>
    <dbReference type="OMA" id="NFQMEPF"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="14">
        <location>
            <begin position="424"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="91"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO12726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="584" mass="64622" checksum="48FC0DD1F3366E01" modified="2023-09-13" version="1">MSTPAIRAISGRAGGALARNTTAQPSYGRTAAYRRIASQLRTYSEASVRARQDGASSILPPFALRSHFLPPSISASRAGSVRHVSFKEMREQRLREKAAGQAEKPAGKAEVKPAAAAAEPEPAKATEPEETEADKVFARFQAEAEAAYAKQQKAEAKQREAEEKAKAKAEAGEGEAEEGAEGEQKEKKKEEEAAPPKHGNKTPWQVFTETLQAEFKASKDWQEGTKQLSGTMHDFTQNPNVQRARSAYAKAAETASTTTGKVFLGTAGAIGKGAAWTWDTLPARAARSAAAAVGSGVEKATRPVRETEAYKSVKETIDDGSSQRYGGWTEKEERRKKREERDRKMGSTSKAPEVYEENPEAGTNVTVHKDSAWKEAWKNMRENNPAMQRLFKMGDTYRESENPLISTARSVTDRIAGFFAENETAMVIKKFREMDPSFQLEPFLNEMRSYILPEVLEAYVKGDVETLKLWLSAAQFQVYHALMQQYTTAGLKSDGKILDIRGVDILSARILDPGEIPVFVLMCRTQEVHVYRNKKSGELAAGMEDKVQQVTYAIGVTRIPEEVSNPETRGWRLIELQKSARDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8F2</accession>
    <name>A0A9Q8L8F2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757134.1">
        <property type="nucleotide sequence ID" value="XM_047900182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8F2"/>
    <dbReference type="GeneID" id="71980912"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01034"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="35997" checksum="07E602F7670EB212" modified="2023-09-13" version="1">MEPPVSREAVYNASYRPMTIIAGETVIAGEPVTPPDDVRRYGKGKGRDRDQPAYTNPYFDEPLCPLETRSSPLEAVNSPYVHTKATDLKATDVKRKTLFDELARFSFDSIRSSSDWSDAQSPATTVSTGILFPEQQPDFSQTIAEDDDEDLDITAELQAGNNSGRDAEAANAAPAPIAGPSRAHIPRARQTDTSPLKPIQHKDIEMGNMSRDISGTTLTASVAKSRSCWQALANAVNGISRAYEEEYFPKTDAPTQQWKAFGERISPAGTIAEVSKAFAGTVYKAANDDFSRKWRSACLKISQCLDIVNEACVNAVVTKRYQPGDHEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8K0</accession>
    <name>A0A9Q8L8K0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-splicing endonuclease subunit tsp-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757213.1">
        <property type="nucleotide sequence ID" value="XM_047900324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8K0"/>
    <dbReference type="GeneID" id="71981054"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01176"/>
    <dbReference type="OMA" id="HPDDQIA"/>
    <dbReference type="OrthoDB" id="10002170at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1350.10:FF:000012">
        <property type="entry name" value="Probable tRNA-splicing endonuclease subunit sen-15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042777">
        <property type="entry name" value="Sen15_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018593">
        <property type="entry name" value="tRNA-endonuc_su_Sen15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28518">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28518:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09631">
        <property type="entry name" value="Sen15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen15" evidence="4">
        <location>
            <begin position="38"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen15" evidence="4">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="22509" checksum="F8F82B121A03C47E" modified="2023-09-13" version="1">MTIQQAPQPPSELQKLLNSHPMSPSSTQDSDLHNLALQIAHNLRYQHLWTDVRLHTNKPETSQPLSRPILSGIPPRRLYVHPDEQIELLQQQKDQGKTGMPELEPQREWVLPSHLREKWTLRRFGATFDAMGTEQGEGEGKGELLFDAEERAVEDENKGSKWRSNLPKRLLLATLEDDSTVVYYIVHDGIVKPRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8V4</accession>
    <name>A0A9Q8L8V4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small COPII coat GTPase SAR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Small COPII coat GTPase sar1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CLAFUR5_00949</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="14 20" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 22" id="KW-0653">Protein transport</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="23" id="KW-0732">Signal</keyword>
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        </ligand>
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        </ligand>
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</entry>
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            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757578.1">
        <property type="nucleotide sequence ID" value="XM_047902434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9D7"/>
    <dbReference type="GeneID" id="71983164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03286"/>
    <dbReference type="OMA" id="DKWAYSF"/>
    <dbReference type="OrthoDB" id="449263at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF43">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="57"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="360"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="847" mass="93851" checksum="E148A8398F6FAD87" modified="2023-09-13" version="1">MARLLSSSSAQRFYTLITYGMMGLGLGCVVYFLLFNTPSTAVRTASSYHDDAGVLRYVNPKIGTYGVTPNGNGGMIPSVSTPFGMTRWTPQTRENFISQCPYDDLDSHIHGFQATHQPAIWMGESGQVVLSPGVGQVQPLFTDRAHRFSKSDERSTPYVYEVTMEAATIEADHNLTESIYSPVPGGAQSVPDVVREGANGRTKRSAEPTAAAVPEFSVLPSGDVAASMRRNEIKVAMTASAHVGHLRFDFDERQDPYVFVQATRKNWTGHVEIDPARREVSGSNSQRQDYLLGPLEAAGFRGYFVSRFSEGFETYGIARGAELEKGAVQGEGEELGAYVTFKGCKRVEVRTGVSFVSVEQARRNLDIEAPKSSSFDQAVENVKEAWLEKLGRVTIEGVNKTDADHDPRTIFYTGLFHALQYPSDFSEPMTEDPDGLRTYYSGYTDNVHASKDSYYQSWSIWDTFRAEHSLLTMFAPERVNGMMRSLLQIYDWAGRLPMWANMVETNIMIGTHVDAVLANALSRNFTSFNISKAWEAVEKNAYEPPIDDTKLLYYDRQGHNLPDEVRAGLTTYLEKGYVANDRWSESASRTLDYAFDDHAAAIVATHAGDITASVELRTRSKNYHTLYNHNTTFMEARNDNGTWAGRDQGWAEGDDWIYTFAVPHDPQGLAELMGGREKMKTKLDEYFDGGYNDHSNEPSHHAPYMYAAIGYPAATQKLVREIAWKEYNATSAGLSGNEDLGQMSAWYIFTALGFYPVDPAGDEYIIGSPFFEKVTIKFPKGAGTGGIGGKERTLVIEAPGATTKPYVKGVRVDGKLLDKPLLRHGEIVGAGSIVLVMSDRPQEWGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9E9</accession>
    <name>A0A9Q8L9E9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757633.1">
        <property type="nucleotide sequence ID" value="XM_047902185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9E9"/>
    <dbReference type="GeneID" id="71982915"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03037"/>
    <dbReference type="OMA" id="PPALPFM"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="7">
        <location>
            <begin position="30"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="8">
        <location>
            <begin position="306"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="836" mass="92419" checksum="111CCAA14046D878" modified="2023-09-13" version="1">MDIQARYQGPALPQISNKRSHSAIRFPFTAYSDAHDLLAVVTTSWDVSVFRIASGQLAFTVRQKSKTTEVTALAWRPDSSCLGVGWTDGTYGIYDGGHGKQIALGSLKAEGEEELWKLDLALNLEEKKPDVEVEHGKVACFGWMGHDLSQNAPNRPQTGLKTTEDWHDGVEDVDSAIGGMQNHGQALPDLPRAITTLDVTKVLPRLSTIPSHFTMQQKQVAAVNKFSTQQATDNMFSQGEGAYAHEAVQSLVVCQDSGESTVLLDETVRIGTCNVQGRPIIHAAHSESPSHAVLCQHDGHSHSLSLIDLPLPTLGGPVLHVITSNTKRMQTLLEYIVQIARCMDHDWKTNIIVQNRFFGSLEALLENTDEPSAVANLYHLAMTGAYNPQLLEWISDVIKDQNQKRWDQVMSALYTNIQAHIFTNLLPALDRITIAVTTLRGLATLHEGSSKFDCEPELFSKILAPIDSLRLVAQHMQSTIQTEYRQFKAFLRWLKMQVEISVAEPLSASALEAEDREVPNLDFSLILPFIQNSLKESKLKTHIEQRPGVEGECSRDEFFASPIIRDVDYEKAKVVLKKLEALQPGEQLLWKEVEDPAALLNIPALICALSGHIRVALKKITEWQSRMLQKPIEIPLDLDSSGSAVVSDMKLRPIAAAASSSPSPSKEEGSITTILLTHKDHIETLSITSSTYAFSKRLSTQPPETQSHHYALPSDAEILDAKWVPRHNVFITLLRADDGQGRILLHPQTPGGISQDAQLLHLFPTNVPFRPMKMVVGGRRNRLAVVVFGNRGRDWKVLDLEAGLRISRIAGEISARRREEGGAGDGEGHDGMEIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9M0</accession>
    <name>A0A9Q8L9M0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757826.1">
        <property type="nucleotide sequence ID" value="XM_047902389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9M0"/>
    <dbReference type="GeneID" id="71983119"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03241"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040430957" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="3">
        <location>
            <begin position="186"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="644" mass="68844" checksum="D285C750B2FB2A68" modified="2023-09-13" version="1">MHSKALLSLALALLPQALAEVGPFFDYCTSNSLYYSTISSKCRSGGASIDLNGGIALVDGQLIWRYQSDPNNGGFYANCGSNAGGNFNLNYATLSCYCYSGGFHDTKSIGLSFLASLFFPFLLTPDSHCTYRSAFRDGLVPPADNPTSSEMRSNTQSTALAAGISLGLVSAQQCTSTISASDYPAPSLAPGWGAHIIANDFVKPRSLRQDNNGHLLVVDQDDDAGGIIRLTHEGEGPCLTVSDRQQIIANGSLNHGIELSPDNSILYASSQEAVYAWPYDPETGDVTGEARRVVSLGGDGSHSTRTLLLPSNDPDYLLISWGSDGNRDPQAREPTSGYSSVKAFDITNTSRVWDYASEGTIVGWGLRNSIGLAQNPIDGGLWSNENSIDNLNRSDVSIVEDNPAEELNFHGYLNGTEHPNFGAYYGYPDCFSVWDLEDVPDNGGLTTGMQFAATTNETVDDAWCRDNTVDPRLSFTAHMAPMDMEFNSAATTLFITFRGSWNRESPAGYKLAAIAFDEATGMPVQPADSMEPYTEIMSNEDESRCPDECFRPVGLEWSAENNQLFMAADASGEIYIVYQTDGTPVDDFTVAATQTGGGESGSETDSDGSSESGAPAEGVGSVVGLTSARSWLLGLIALVAAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA78</accession>
    <name>A0A9Q8LA78_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758094.1">
        <property type="nucleotide sequence ID" value="XM_047901811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA78"/>
    <dbReference type="GeneID" id="71982541"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02663"/>
    <dbReference type="OrthoDB" id="3890337at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="200" mass="22876" checksum="6647129CE0B326D8" modified="2023-09-13" version="1">MLLEETTMEERAEQDYCQRTRELQTAQDRFDNRLAVHNQEAAQFHTRLRRGQTLDDKILEFDMRHYQRGQQLTRELIEAEERFAVAKQNAIRLGVRTEGDDRTSGFLDDQEDGLVIYQRPPKDRVNQGRIHAWLNALPGKFGTSAISLGPEAWPEVDDWDAGMELGSSDSASVVAGGSRRRRIQSYRAAMDRVKDATNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBA4</accession>
    <name>A0A9Q8LBA4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein ypt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758613.1">
        <property type="nucleotide sequence ID" value="XM_047902383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBA4"/>
    <dbReference type="GeneID" id="71983113"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03235"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
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        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="11836" checksum="D030503F17BBCD7A" modified="2023-09-13" version="1">MDSFNNVKQWLQEIDRYATEGVNKLLVGNKSDMSDKKVVEYAVAKEFADSLGIPFLETSAKNASNVEQAFLTMARQIKERMGNTTVNNKPTVQVGQGSNVQSGSAGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBB5</accession>
    <name>A0A9Q8LBB5_PASFU</name>
    <protein>
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            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03239</name>
    </gene>
    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14254.1"/>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LBB5"/>
    <dbReference type="GeneID" id="71983117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03239"/>
    <dbReference type="OrthoDB" id="3360032at2759"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="15980" checksum="0246B412174E1839" modified="2023-09-13" version="1">MLSIIDWLPPEGFINFVFANYPLLVFYGQAPGLSQPRITYITTQTQLPAMFPLLQMPAEINLQIMSHLSPFDTMVFVLSNYQVLARQGIAPSLTSETVSQLRNALRSRRNTPPDRDGRGHAQEWALTRPHAANMPISNAGLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCK9</accession>
    <name>A0A9Q8LCK9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047907440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCK9"/>
    <dbReference type="GeneID" id="71988170"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08292"/>
    <dbReference type="OrthoDB" id="3650808at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="14771" checksum="FDBB00746084A3CA" modified="2023-09-13" version="1">MSEPISKRRIFPFFDLPRELRDFIYGFSLCDKRLEPDHHSAIWVTDVAPQNTMRVSRQFNEELREQVQKKAHLYIAQDYTTDPAPIQANTVPQQNSLRFLTVSIELNNGMFGLQAQRAWVVQAIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCS0</accession>
    <name>A0A9Q8LCS0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759433.1">
        <property type="nucleotide sequence ID" value="XM_047907261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCS0"/>
    <dbReference type="GeneID" id="71987991"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08113"/>
    <dbReference type="OMA" id="KNPCGAQ"/>
    <dbReference type="OrthoDB" id="2439692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF2">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040468952" description="DUF7707 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="2">
        <location>
            <begin position="32"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="23009" checksum="00CF64211A43D41F" modified="2023-09-13" version="1">MRSFTAVSIATLFAASGSASIFGLPKRQQVYAIDPNSVSMPTRDFWCKQQRAQCPLICSQTTPSQSLGTLANDCDDDSLTYACVCENGLSPNVSEYSQTLPYYLCQEWGNQCVSNCDGNSQCQGACRDDHPCGAQSPTRQNTSTLTSTIMSTTTAAGGAATTDASGETIYSGFGGGAQATNTGGSGGGESAATHIRVWALSAGQTFGTLAVVAGFVGGFAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCV3</accession>
    <name>A0A9Q8LCV3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein glo3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759400.1">
        <property type="nucleotide sequence ID" value="XM_047906970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCV3"/>
    <dbReference type="GeneID" id="71987700"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07822"/>
    <dbReference type="OMA" id="PANQVCF"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048205">
        <property type="term" value="P:COPI coating of Golgi vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000013">
        <property type="entry name" value="Putative Arf GTPase-activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="487" mass="51669" checksum="DA0D5955F76502BB" modified="2023-09-13" version="1">MALAPKTESQKLFEKLKRKEANKICFDCGGKNPTWSSVPFGIYLCLDCSAHHRNLGVHISFVRSTNLDQWQWDQLRRMKVGGNESATKYFQSHGGSAALASKDPKTKYTSNAANKYKDELARRVEIDQKKSPEIVVLEDAADEAGGSGTNTPAGEPADDFFSSWDKPAIKRPSNPPSRTGTPSTVGRTASPFLSANANGNGTARPKSPLNPTDGTAAPPAAARSVSSTAVRKTAVASKPKANILGAKKTKLGAKKIDASALDFDEAEKKAREEEERKARLGYDPDEETPAEATINAAQPASATATIHQPTPVSPPTAGGFGAAGKPRERSDSEMERLGMGVRRLGFGQIGGGKPAAAPKAAMGFGSVGRAAPAQDDSEKYAREKFGTQKGISSDEFFGRGMHDSNAQTEAKSRLQGFEGASAISSNAYFGRPEDEGQSEDYGDLESAAKDFVRKFGITAGDDLENLSSMLGEGAGKLQGAIRNYLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCW0</accession>
    <name>A0A9Q8LCW0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759478.1">
        <property type="nucleotide sequence ID" value="XM_047907367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCW0"/>
    <dbReference type="GeneID" id="71988097"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08219"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="35482" checksum="AD08B41791C2A46E" modified="2023-09-13" version="1">MTEDCWSADTSGCNPTTKRWLALAGQRALSRVAERTQEDLVQSEQPDLQNLRWTAPILRKERKDDRLSLRLAIIARDMDEFCLVTDLATCSADAVLDAASEFLLGCAGIAMTSDYENGMTIDMPAVNTTRGPQASAAMFECVALVLCQLARYHSRWISSDGPAPVVLWNQIVPGTGGPRVRQSSAVTMKFPPALHKASNTGKRFATNQAQGAHWDTLKEKTFEMFLCGMPENDSQFAEIPIRVALSVNVLAGQGRDDPALGSISFEYSNEMQKFARQGLIAITRYIDTSFPAATTADTILEPYLPSSTLRPRPATTNSMLLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDD6</accession>
    <name>A0A9Q8LDD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758999.1">
        <property type="nucleotide sequence ID" value="XM_047902118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDD6"/>
    <dbReference type="GeneID" id="71982848"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02970"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF4">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="101"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="280" mass="31654" checksum="52918F20C7CA48DA" modified="2023-09-13" version="1">MHKDFVKILVLETDEPHPDTQHEKGSFADIFNHLFTKAGQSHDPPLGVELDQHFVVDDPEHNHHGHVPHASEIPEDVHAILITGSMYDAHGDDPWIVQLRELVKNLWTTRPEIKFSGVCFGHQLLARTLGAKVEPTPGERWELSHTSMDLTLVGQKLFVTNDKTLTVHQMHQDHVTTVPSSETTDLLDAGTKVHVWASTEHTEVQGLYIRDRLFTSQGHLGFDENMVHRQIELRQKSGAIGKKDLEQVREAQEKAHLEHDGEVVAAAVVRFFHGDDHDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEX2</accession>
    <name>A0A9Q8LEX2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="8">PPIase</shortName>
            <ecNumber evidence="8">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="8"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760662.1">
        <property type="nucleotide sequence ID" value="XM_047903456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEX2"/>
    <dbReference type="GeneID" id="71984186"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04308"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000032">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF385">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="69"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="222" mass="24220" checksum="98212B240D343EFF" modified="2023-09-13" version="1">MFSPSTLLRPTTFNTFRTCQPTFNRCFHASSANMVIKAYFDVTWTGPELKTDTNGKVISKDESAKPRSGRINFDLFDDVVPKTAENFRALCTGEKGFGYAGSKFHRVIPEFMLQGGDFTRGNGTGGKSIYGEKFADENFKLTHNKPFLLSMANAGPNTNGSQFFVTTVVTSWLDGRHVVFGEVPDDDAESKGIVKSIEACGTSSGAIKYKEGPPTIVKSGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY7</accession>
    <name>A0A9Q8LEY7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760616.1">
        <property type="nucleotide sequence ID" value="XM_047903081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEY7"/>
    <dbReference type="GeneID" id="71983811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03933"/>
    <dbReference type="OrthoDB" id="3801343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="23838" checksum="65E862CF743840CC" modified="2023-09-13" version="1">MSAIRSIVGADLAVQQPTSRLLGLPAELRNKIYQLVLCDPNRRSLLWDEENWCSISHTPAPSLLVTCRQINSESVSYFRFFQHAEFLFASGIKEFLGQASAADKKSVLEMTLLAGDLEEAERMLSLLERFPRLDKITIRWMEYPWFGTADIVIGLEWRRERRSALLRGVASLKKICFDPSEILLNAHFDQRLWAVEVALNAALVERSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF78</accession>
    <name>A0A9Q8LF78_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Srp40 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760653.1">
        <property type="nucleotide sequence ID" value="XM_047904025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF78"/>
    <dbReference type="GeneID" id="71984755"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04877"/>
    <dbReference type="OMA" id="QQSILHY"/>
    <dbReference type="OrthoDB" id="5599646at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05022">
        <property type="entry name" value="SRP40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Srp40 C-terminal" evidence="2">
        <location>
            <begin position="327"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="395" mass="42358" checksum="7482051D7FA978C2" modified="2023-09-13" version="1">MAPTRKERSEATVPSELWTADDIPAPRLLDVLTQLAHFFDQIGYKKTLSALAKEASSQSELSLDVAAWTEQIGAKNAVPLLSLHEEWHEGNDKFPTLQAPAVAHDSDDSDSDDDSDGEKDDAEAVLVDVEAEETSDDDSDEKESSASDSSDSSSSEEEKEAPAKAGAKRKRVASPPSSSDHSSDASSSDSDSDSSASSESDAPPAKKARKSSPVKAAKAKKANKAKSSSSDSDSSSASSDSSSSSEFEEEKPAPPPEKKEKKAKAVKTSSAPSSSSSATLEAESSPEKEEAPVSHVHPDRLRQVPDQAPKPTTKKETAAQLKKQQIPFSRIPADQKVDEKFASNEYVSYDYADRAHRDLIVTRGKGFTKEKNKKKRGSYRGGTIDLAPKGIKFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFF7</accession>
    <name>A0A9Q8LFF7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_03996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </evidence>
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    <accession>A0A9Q8LFY3</accession>
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        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI38</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="41678" checksum="62CAD763F4D60DC6" modified="2023-09-13" version="1">MTLIKSPRLIFVFATVCFLSLSLLLYQYDALLARLRIANVLTTDAGTPRGPYASSYGRGNHWHGWSNIHHVFIFGDSWTTTGFEIDDAQPTVENPLGNPDWDPRNWHLGAGTNWVGFITAWHNASLVRTVDLAYGGATVDMDLIHPFEEIPPGMRDLGYQVNELFKPKYAMHPDYFDWTNENSLFIIWIGLNDVHNANVNNSMRFGQVFEQFRNHVEQLYEMGARNFMFLKIPPIQRSPLAAREHMVENWTSWVSAWNTNLTTLVQTFTHKHPDSIAFVFDTYKLFHDVMEDPCSFEATCEFKDVTTACVWYAWGTDEWNSWNENCTYRIDEYLWMNPIHPTTRMHNLTSLLMAEALMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIC2</accession>
    <name>A0A9Q8LIC2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762388.1">
        <property type="nucleotide sequence ID" value="XM_047905356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIC2"/>
    <dbReference type="GeneID" id="71986086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06208"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13086" checksum="03E5AEA35531F150" modified="2023-09-13" version="1">MLGHKLEGNPKTCPNCPHGRLLYDEQAVIKEIIYPDAAGPLPQNTRSYTPASSLNTINVLSRFASPRYISGCLDEEDSGVFSENELTPSSSEATTPSTEEFLVLLSRIGQIFVEEPDGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIG3</accession>
    <name>A0A9Q8LIG3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06444</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762461.1">
        <property type="nucleotide sequence ID" value="XM_047905592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIG3"/>
    <dbReference type="GeneID" id="71986322"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06444"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="38"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="303" mass="34179" checksum="BAD696B5BB3BD3F2" modified="2023-09-13" version="1">MSKRKLRSDTAAGGVDEGVLEDTTIAAPRAKKAKKDVVRYLCYICDRERSAGAFPDYNPSSECEHNINTCKSCLKLWVDVSLEGAQTTISEDRKVFGLKLISVDSKACLYKYSYGYRQCPECEGIMKNVNIQIATTKKMHGMFEKMERKHIADNTPGWRWCMAPNCNAGQVHEPKIIDKPKEPPKSKSRSKKKAVDPETDVEDIFTCNECGARACVTCDRPYHEGETCAAYQLRIRDRTVEEDKSLLEIERVTRKCPSCKGSIQKNGGCNTMFCFACKVLFCWNCVSPFEQGAYCKCNPRPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIJ2</accession>
    <name>A0A9Q8LIJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 14">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_06268</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 14"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762490.1">
        <property type="nucleotide sequence ID" value="XM_047905416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIJ2"/>
    <dbReference type="GeneID" id="71986146"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06268"/>
    <dbReference type="OMA" id="DNAHRQC"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990467">
        <property type="term" value="C:NuA3a histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16866">
        <property type="entry name" value="PHD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="16">
        <location>
            <begin position="123"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="MYST-type HAT" evidence="17">
        <location>
            <begin position="460"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="237"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="345"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="609"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="840"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="7"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="840"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="906"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="970"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="986"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1045"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1064"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1076"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="12">
        <location>
            <position position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO18124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1095" mass="121834" checksum="F782ADE343BFB29A" modified="2023-09-13" version="1">MSGSAMELDEEPDAPIAEEEEVGEDIEVGNPDADGEPDDSDQDAEGEVDEENEDDEDGEFVGAVKTRSVRPRRRKASGEESDAEVEVEDEDDSEADTSPGGEEDWEAADDVEEDDLKVGNADASRCVFCKQTEEEDPGEEYEDYLACRVCGDNAHRQCARDADTLAADEDAEHWRCQDCVANGLEEDFKDVPHMLENRRRSSAPKMARDLLPAARGGIKPGSHSVFNTLILPEDLQDGSRSLRKRKTPSEDIDEPPRAAVRKRMRATPDDDEEAPTIVEEPIETNGDAENEQPDSPQSRPLRPHRHTKAQSVGARIISRSEDPKSAIIAIPVSIAQWDQIEKDVQKKQKRRERDRQRRLRNNQSRRTATAEPEELTHFPAVQTDMYNNPFFPFQDKEVDENKGRPYGGILTDAEADTTRTYPQDADREAFQNARDKAEQEWREKLARQPGETPARSKQSNAASKIKCINFGQYEIDTWHAAPYPEEYSRNKHLYICEFCLKYMSSDYVAWRHKLKCSAKHPPGDEIYRQNIRNPETGAETTLSFFEVDGRRNPLYCQNLCLLAKLFLGSKTLYYDVEPFLFYIMTENDEFGCHFVGYFSKEKRGCGPPAPVDARTSFEDAQDSHANSGTDADLTDTAADPALSNPGNNVSCILVLPVHMRRGFGKVLIEFSYMLTKVEGRTGSPEKPLSDMGLVSYRSYWREVICKLLLTYEGKESTTNDSRPLSIVRIAKTTGMTPDDIVSTLEALRFLVRDPVTKTYALRLDYDYMKEYVEKHEKKATIKLDPANLVWTPYVMGRPTNLFAMGEETNQPLQTVAAREEPIEVPDQPQEGVLQALKAPDLAKSHKDSKGDANVTTTAPDVAMGKTTEEQPQAQLNGSSPKSRKKTPPPLTLTPQPSKSERPPTKGSPSRRSPRKTPNGSVQFIESGEASPASFYSGSQPVSAGPIPPTRFEVFPPVPGAPPAAKRRPGRPFGTRRSGNRTGSTQRRSRTGSSRRNHKNNQSPSHGASSASALRRTRSTLGEVAMAATDADEDDPGGAGAAVEAAQEDADADVNVGLDEDQELDNDHDQDDKADADHEEDEDAPGEEDDEEIQYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIZ3</accession>
    <name>A0A9Q8LIZ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_06364</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762616.1">
        <property type="nucleotide sequence ID" value="XM_047905512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIZ3"/>
    <dbReference type="GeneID" id="71986242"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06364"/>
    <dbReference type="OMA" id="GEFRFCK"/>
    <dbReference type="OrthoDB" id="302728at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="152"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="335"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="455"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="484"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO18250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="573" mass="64483" checksum="E5453FA690DF4B49" modified="2023-09-13" version="1">MPSTSFSDMPTLAAPTSTPSPPFHRRRKSWARKLERCCCQTFAYFPLTFVYGLTTWAVYVEVDVSFLGIHTGWAYFRAGQGILLYALANVSYTIAVFTDPGSPSDPKLDNSNTGSRKGGGYEGLPTFEDDGDETDGVVPAEWMTTVTAKSTGQPRYCKKCNNIKPDRTHHCSTCGKCVLKMDHHCPWLATCVGLRNYKAFILFLVYTSLFCWVSFAVAATWIWAEIIDGSQMEEGLRVVNVILLSVLAGIIGLVLSGFTAWHLYLCLTNQTTIESLEKTRYLSPLKKSMEHQFRENRNYLGRETHSAGDIAADEDQSLGDRLRAIHANALPGVLRPEEGDASLTPSRDPSPIPPAAASASPAHQSLRRSYASLEAQRERDRYNSYLDEQDSEKLPNAFDVGWKRNLRHVLGNEPLYWFLPICNTSGNGWQWEVSPRWNEARDRIASERDRRAREEALWNQGAAPQRSFEPPPRDLRWTPGQGFVDRERHAVHEGRRSPAKHLNGDSSMQMQPLDRRKHSSSSDVDYDTSSDEEGRQKKNPSATANWNDIPEDFLDPKASQGRRSRSQARTKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P322</accession>
    <name>A0A9Q8P322_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA repair protein rhp41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00089</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755720.1">
        <property type="nucleotide sequence ID" value="XM_047899237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P322"/>
    <dbReference type="GeneID" id="71979967"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00089"/>
    <dbReference type="OMA" id="IPEWLMS"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.290">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018327">
        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="510"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="570"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="9">
        <location>
            <begin position="634"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="339"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="892"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1046" mass="115355" checksum="3DA8C202086298F0" modified="2023-09-13" version="1">MAPSRGKGKAPVDPVASRSTRSQRSTTRSKARGGDDVPDVYASMLAETDHSELEHSDRPLKKRKVTPKGTRAVEKTVSTPSRASKPVPAQQPSSAASIAAARPISTRLQTVEDSSDDESEFEFEDVDLEGADASADEHPDGIEDLSISVQPESSIRRAQNRRKPATSAEKAHRLLVHKLHILCLLGHCMYVNGRCNNATVHKLLRRLLSARAISYLNPKTEHSQFQRNRSFLDGLQQATDAFNGEYHVTASGMIKPIWTVDGEEPRELDHLPPVDRSDFVAAAKNMEGSQDMGNQLFCAMLRSAGVDARVVCSLQVLPFTSVPKGSTPQKPVKERILAIAPDTDLSKTDSSADESAMKGSSRAAIRRRLGQPGFTAPKTSATPPKKKSKHIPKLSYPVFWVEAFNAAHQKWVPVDPVVTHSVNKPAKLEPPISYDLNQMTYVLGFEADGITRDVTKRYAKAYNAKTRRHRVEASKDGSKWFKKAMRIFRRKGGANDRDQVEDAELAQKEAREGMPANVLDFKDHPYYALERHLKRHEVLHPKREVGKVNAGTAAKPRMEAVYRRQDVQICKSADKWYRVGREVLEGEQPLKHVPARRKRFQTPDDEDAEPDTTPMYAPYQTQLYIPPPVDKDRIPKNVYGNLDIYVPSMVPAGAVHLRAPRGVFDEPTDQDRKQFTDMAQRAAKLLRIDYADAVTGFKFQGRTGTATVDGVVVAQEYADAVRTAIEGFEYEAEEDASKARSLLALKLWKRFLTGLRIAEQVREYGDGTEDRDAVHERIDAAKAAEEGPGMFLEGSEREPPLITAGLYTIEELLRPGGVTKQRKRKKIDEEDDELMEYEQHDGTIGPDFGIGDEGGGFFPEHRSSAECSHGGGGFLPEAGEQRIFHEEDGGFVTGPEPDGTENGGGFMVDNDDGGGFIADEADDESGLIPHDETQDGGFVLDDEPEGGGFLPDADASHNDDKSIAAGDESQQFSHDSAMVQEIRQTEQDASALQEIPKTSFREPAGSHPSQQTDAAELDSGNDSDKGSLLSHDPEDDDAEPDWLLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3H1</accession>
    <name>A0A9Q8P3H1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756155.1">
        <property type="nucleotide sequence ID" value="XM_047900563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3H1"/>
    <dbReference type="GeneID" id="71981293"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01415"/>
    <dbReference type="OMA" id="RDWKPNG"/>
    <dbReference type="OrthoDB" id="5408734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="18778" checksum="450F9FB5C6A76DE2" modified="2023-09-13" version="1">MAEEQDPPTQRFNTRPESTIAQNFASDLDAMFGLDSGGVDDLSRTVEEKKQTVTTGEQQLQELEAKLRETEERLARVSRHNSPSRHALPTANADNDQAGDGAPRPSPLAQKPTYPADRPPTAGDRPQSGRADTQTMMAGVPGAMPPHTPQPNGGSHDSYVMVDRSAAQAQRSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Y3</accession>
    <name>A0A9Q8P3Y3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate dehydrogenase assembly factor 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756533.1">
        <property type="nucleotide sequence ID" value="XM_047901069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Y3"/>
    <dbReference type="GeneID" id="71981799"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01921"/>
    <dbReference type="OMA" id="GGDWSYN"/>
    <dbReference type="OrthoDB" id="201362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524:SF3">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="17853" checksum="235E198105DDEC1F" modified="2023-09-13" version="1">MQCTRVIRTIRPGFFRRPFSASTAIKSSWSTGPSPPRLPKEEQEIFERLQKQSTGAFSTPKQPEQDTEKHKDVDVAAESAELGNATVRSGEADKMLEQLRERARLAAKGDGEELHPNVRRGAAPEFDGDTNPQTGEVGGPKNDPLRWRGDWSYNGRVTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P528</accession>
    <name>A0A9Q8P528_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinetochore-associated protein MTW1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_03218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757939.1">
        <property type="nucleotide sequence ID" value="XM_047902366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P528"/>
    <dbReference type="GeneID" id="71983096"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03218"/>
    <dbReference type="OrthoDB" id="1884855at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO13573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="40436" checksum="9B873186A3B59455" modified="2023-09-13" version="1">MLTRVYHRSTGQRREHGASPPSPTFADRRSHLELHQDNTMASNKQTTNALLTEHFRYTPLTLLDDIINTVNELVFRAVNAIEEGFGGTTAQQLGFQLDEETAVSLPNDEARRERLAELKQNEVDNGIVKLESLLNATVDKDFDKFEIYTLRNILAVGHAEEDLANWVRLDHYKGVDVVNADEVPTPQQVQLQRRKLHETAKLNTMLKAEEARNAAILSQLSRLIGAEPKQEGEESENKAPFAFLKSSEATAQAQNLAQDTQETLKQIPALQQLLEKLKDAMQNNSNPRQARFDDSDSMDGRRRQYLNAQTRRALERKGIDPESGAGSSLTAGRRMGREELEGIESVAQALGGAQNARSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5D5</accession>
    <name>A0A9Q8P5D5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit</fullName>
            <ecNumber evidence="3">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03047</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758376.1">
        <property type="nucleotide sequence ID" value="XM_047902195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5D5"/>
    <dbReference type="GeneID" id="71982925"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03047"/>
    <dbReference type="OMA" id="SHFWMSG"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000026">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="11">
        <location>
            <begin position="47"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="10">
        <location>
            <begin position="219"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO14010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="521" mass="58065" checksum="1D0CD1919C9AF95F" modified="2023-09-13" version="1">MPYNIAMISDFFYPQPGGVESHIYHVSSKLIDRGHKVIIITHAYHNPTRTGIRYLTNRLKVYHLPHWVVYRSTTFPTVFSSFPHLRQIFIREQIQIVHGHASLSNLCHEGLLHARTMGLHTVFTDHSLFGFSDAASILANKLLKFSLSDVGHVICVSHTCKENTTLRASLNPLAVSVIPNAVVPSNFRPLQSHEAQGFLQSDKGALLPPPPDPSKPVGPGDPITIIVISRLFYNKGTDLLISALPLLLRRHENLRFIIAGSGPKAIDLEQTLDSLPQQLVYTPSGQSRVKLLGSIRHEEVRDVMIRGHLLLSTSLTEAFGTVLVEAASCGLMVVATRVGGVPEVLPSNMTVFVLPEVEDVVRGVTEAVGLLTSRTVRRDKFHDLVKNMYSWSDIARRTERVYDLITGHPPATDNQGFYDGDWNNYGPPSQGSNALMDRLKRYYGCGVWAGKLFVIVVVIDYLIYCLLEIVYPRDGIDICKAWPAIPSTFEEEGLVNGEVERFGTIGQGRRIRREPDFAVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5L5</accession>
    <name>A0A9Q8P5L5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Homoaconitase, mitochondrial</fullName>
            <ecNumber evidence="5 17">4.2.1.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 17">Homoaconitate hydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_03230</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>(2R,3S)-homoisocitrate = cis-homoaconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15485"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:58174"/>
            <dbReference type="EC" id="4.2.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.36" evidence="5 17"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758616.1">
        <property type="nucleotide sequence ID" value="XM_047902378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5L5"/>
    <dbReference type="GeneID" id="71983108"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03230"/>
    <dbReference type="OrthoDB" id="10262323at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004409">
        <property type="term" value="F:homoaconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01674">
        <property type="entry name" value="Homoaconitase_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000013">
        <property type="entry name" value="Homoaconitase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000016">
        <property type="entry name" value="Homoaconitase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004418">
        <property type="entry name" value="Homoaconitase_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039386">
        <property type="entry name" value="Homoaconitase_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00139">
        <property type="entry name" value="h_aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0408">Iron</keyword>
    <keyword evidence="11 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="13 17" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="19">
        <location>
            <begin position="112"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="20">
        <location>
            <begin position="613"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="587"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="744"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO14250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="844" mass="90067" checksum="DAFE7ED7C61E2979" modified="2023-09-13" version="1">MALRAGAGAGAGAGRSLQRLARTTVFQPPPCIAASRTSLPMATPLQHGPRDISSTRPTRLAQLTDAFSSQLQNTPADILHSAKSTPTTPQTLTEKIVQRYSQALPDGKFVKAGDYVTLSPQQCMTHDNSWPVATKFMSIGATKVHDPKQIVMALDHDVQNRSEKNLKKYEQIEGFAKKQGVDFYPAGRGIGHQIMVEEGYAWPGTMAVASDSHSNMYGGVGCLGTPVVRTDAASIWATGRTWWQIPPIANVTLTGILPEGVTGKDVIVALAGLFNNDQVLNHAIEFTGSTNTMRSLPVDDRLAIANMTTEWGALSGLFPIDDVLRGWLRFKATEASMYKSPSETASLTTDRFNHERLDELFANPLSADKGATYAKELFLDLSTLCPYVSGPNSVKVATPLNELEAQDIKIQKAYLVSCTNSRRSDLEAAAKVFKSAADVNGKVPKIADGVKFYIAAASLPEQKAAEEQGDWQALLDAGAEPLPSGCGPCIGLGTGLLEPGENGISASNRNFKGRMGSTDAKAYLASPEVVAASALQGKIAGPGWYEKPANWSGVSRGYGDGVKDEERMISIEDALEKIIQQADSAIEQAETKLSSSSTESSSPAEETSTGLTEILPGFPEKVTGEIVWCNADNVNTDAIYPGKYTYDDAFSSDPAKMATVVMENYDKEFAKIAKPGDILVSGYNFGCGSSREQAATAILAKGLPLVVSGSFGNIFSRNSINNALMGVEVPKLVERLRTAFDGASPAATGKAGKAPITEPAQNSQSLDSPPPAPQATPAEKPLTVRTGWTFTWDVKRSLVLIQEGEGGESWTQKVGELPPNVQDIIAKGGLEKWVQSQIASESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P613</accession>
    <name>A0A9Q8P613_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA polymerase III RPC4-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758842.1">
        <property type="nucleotide sequence ID" value="XM_047902148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P613"/>
    <dbReference type="GeneID" id="71982878"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03000"/>
    <dbReference type="OMA" id="LQFPPMT"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="623" mass="65575" checksum="8E0DE303454AC07F" modified="2023-09-13" version="1">MPPKLETPVNGDATPNQQSAAGSEQTSTGTTQPPNNDAPTPTPSASGSTPAPRPASQSRPSPAARGRGGVVPKPKFVGRRSQTQRQELEQAAAKQKAAEAAAAAEEAKRSAREAKRFGYGRGGGDRGRGGRGRGRGRGGHMADSNRQREEAVPSGPFSAGQAAHDASSRRWGPSGGGGGGGGFSAGGGGSGSGGDSRYSGGGRSSGMGGGSGIKAEPGMNSSMGGMHIKAEDGGYISSDDEETKNQGPKANIDQMTVIDLEGGETNYDAMAPVRLSRVPHRDRMVGLSAEDEGLFDSSDQADGADDKKKGKQRAKDVVVTGSTQRSKRPTAYSSSDTDGEIQIKEEPTDNDQTRPATPEPVLATDPVLQQSPVSSPESRSKAKEKVKATVDAAHQDDEDFVFASPPRFQTQAEKDEWERLQHDMRELRKELGALVPPSALVPPDADGDTAMPETTPAIERMKQTQTERELHVYVFQFPPVLPSLKPVLVKPDPETMTDAQAGEEAMDVDKEPIEIKDKGIAYKQPTLPSGSVGKLRIHKSGKATLDWGGTPFVVAKGADATFLQNVMIGELPDVKPPAPAKDAKDKDAPPVPVDTSNMSARGLGMGQIRGKFVVTPDWDEILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P645</accession>
    <name>A0A9Q8P645_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </evidence>
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    <sequence length="472" mass="53445" checksum="7D45955BB6CE67D6" modified="2023-09-13" version="1">MSDQDLVWVDQKELWIDRRSETATAVRQHVMLNYLRKPQSLTQPSECQDSVKLKSRPHMPTKKLTDMRRTVSKQPHAGRGRLMSSKNARTKAGCEREYTPDPTLAIASDEDVAFSQASWWHSYFPSGDYYADWIEQCRISWNRRFWAFSKEDPILRELFFSINAAKEASVRGLPRSKSYYTHKGKAMCLMAADIQNGNVRRTAFAAMCLLCKTAFIEKDFEAAMSHMLAISAVTSQAKGKELEALWLCVFADYRIDHQECDATLQDFITWADMNLMGATRRVPGVSKAQGIERHDSTLARARDQRVVFLADCNVLSMPASSELSTKRFRTMLHMLHSLAAAYDTPAGGDTGVSSPWTLSYDLAYQLTNLRERLEGKRDWTNPLKHSPHRAFLLASRVQYWGMSSQFVPQADLESGTLTQASCGHSGRRHVERAYGSLSRQMDPVWWEARCTVVGTVQRRCKADQASVCGGAV</sequence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="20928" checksum="5420234B4A52C757" modified="2023-09-13" version="1">MAPKDKKRKAEEVEDAADTPAKKAPHHEDLQGRENAATAIEWLSKLGVDLAANETATPGWKDVVAMGNRWVEMLAQHLVREKQFIKIMQNAPDLSSISISKKWLSTVNLPYRYNNFDDFKKFDSRWWSAPKGGIERRLAVVQRAIKIYSEKIGMQQTSIEKTYISAPSNDEESNTQRESIFLY</sequence>
</entry>
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            <end position="233"/>
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    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <sequence length="234" mass="25444" checksum="065A77CCDA6EB178" modified="2023-09-13" version="1">MSFHGRVNMDQATIAALVESYKIGTRQVAQWLVKSARGHISSRRLAAAVELAAAQYGIAHSVQLESYDLVQLAEDIEEHVASSGRTPWDISIVLAVLHSTIRSRKGCAEWYKARGARTEEQLSLNESHQRFIDALIAVSNCLRRVQQAANGAAPQVKTASALAKLTGAPFTQLDLEEPGEIPDIPTVEVVEHAARIVTDGDIAANIIDEPDDSAFAIAGILAECYDMRQFLRAV</sequence>
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    <accession>A0A9Q8P6X9</accession>
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        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="303" mass="33416" checksum="49E5E1ADB4513C0C" modified="2023-09-13" version="1">MSINLSVTISLETIALIHQSEIVLEEARTEFEAALADVASSVIEAVKALPYDITISDSDYPGPCRSRPPSLRHSVQPSIQDHDSSYAESPPTTFPSTPVICSGSWSSLPAYDPQNGEEDFTINVSDLEGLQTTFCVSVFGSTTISELADMVHDQSGIPPDQQRLIWRNHRLDQPDATLSSYGIASGEDLYLLRQLLPSPDMTAANDGIFFPESEFDFHIQTISGKQIPVAARYSTTTAELASAIFDYNCIPPNLQRLIHKGRVIYDGHSHEQGNAFPVFTLEEVNVAHDSVVQLYFCNTMRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7B5</accession>
    <name>A0A9Q8P7B5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Senescence domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760088.1">
        <property type="nucleotide sequence ID" value="XM_047903779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7B5"/>
    <dbReference type="GeneID" id="71984509"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04631"/>
    <dbReference type="OMA" id="WDLGPES"/>
    <dbReference type="OrthoDB" id="20821at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009686">
        <property type="entry name" value="Senescence/spartin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045036">
        <property type="entry name" value="Spartin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068:SF43">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06911">
        <property type="entry name" value="Senescence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Senescence" evidence="2">
        <location>
            <begin position="245"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="512" mass="54331" checksum="9D09BCAFF49CCE63" modified="2023-09-13" version="1">MASHNDPKLLYAIKGIKAYHIQDGQEQDLTPSGPQTLSLLMVPTSSHFAPTTMGANEVPDEDFYLHLNLPPELDLPLPATTQVYHQPPHSYLIPRWDLGTGAGAFTRIEFPPLGYGVTQDDVDTFETILAQCTAFLERARPPMPTRPSFNEKGGYNPTDYAPGGRYAVDDKTGRKHGEIVLIDEDNGSVVGELGEGAQVIEDSKLKPGSKDPVEVQVSADGKTIEVRPVSEEYLRMARHPAYKSSSIVQNAATASRLIVTGSSYVGNMLASGADNFTQKTKPIAKPMEFKPATHERVRKINTFTQKTASVSNKTVGSITNTVQNIAAKASGHKGDRPHKGYDEKGRPLSKDDYKPGFLNKSMIAFSTVMDGIATGGKTLLETGGAAASTVVGHRYGQEAGSITAGLAGGVKNVGLVYIDVTGVSRRAVIKSVAKGMVVGKVRGGGEIVVGGGDGGEISTEELKKMEAQQSSSVAADHGGFQPQGGAYDPVGFGSSAPPTYQEFGQPGASEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8G3</accession>
    <name>A0A9Q8P8G3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase ptmU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05767</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761571.1">
        <property type="nucleotide sequence ID" value="XM_047904915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8G3"/>
    <dbReference type="GeneID" id="71985645"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05767"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="45903" checksum="82B8A5A294D6E784" modified="2023-09-13" version="1">MNADTLRSMTSPMTDFHREVIWAAVFLGIGILWTTTVLTRKALPFPIVNEIKSCLNIIEVIGDGWHELDVKKDVLQWVARLSARIFLPRSFSESKEWCRISIEFTTSAFITMAIVRFLPRFLRWPVERLLPLCRKVRADYRAAAMMLTPVLEERQKEIAAARREGRKPQLPDDSIEWFRNSANGRQYNEIDIQMGLAVAAVHTTSDLLVQALLNLASHAEILKPLREEAVSVLTQHGWQKTALTELRLLDSFLKETQRLKPINMATMHRIATADVELSNNVKIARGQATAISSHEMWSESNYENATQFDAFRYVKRRQIPELEHNSYLVATSPDHLGFAHGKHACPGRFFAANEVKIAMVHLFLKYVFKLGDPSHAVWREFGTAMIADPKAKLSKIELETLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8J4</accession>
    <name>A0A9Q8P8J4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761569.1">
        <property type="nucleotide sequence ID" value="XM_047904913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8J4"/>
    <dbReference type="GeneID" id="71985643"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05765"/>
    <dbReference type="OMA" id="ADYGSCD"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="300" mass="33782" checksum="843CC3BD9004730F" modified="2023-09-13" version="1">MSITTVALLGADGNLGPSIYEALTSNEFDVTVLKRKSSKSNTKYPKQVTVGDAFEVDELVDALKGQDAVVVTVKGSQTDLQRRIADAAVRAGVKRFIPADFGSVDSSSPLTQELVPLYKHKSAFREYLIELAKKHPNFSWTSLVCGHFFDWSLEFLHVWLQDRRVEVLDDGETKWSASSLSQIGKATVRILQRPEVTKNRMIYIQSFLISQNEMVSSLERATQSQWTVVKRDAKEYQLEEKRKADAGDLKAVENLVWLLGAIDANWEEKKDFVMRDLGLENEDLDTVVKMTLEKHGNVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8N0</accession>
    <name>A0A9Q8P8N0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rho1 guanine nucleotide exchange factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06091</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761659.1">
        <property type="nucleotide sequence ID" value="XM_047905239.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71985969"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06091"/>
    <dbReference type="OMA" id="DMFYHPG"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057283">
        <property type="entry name" value="RGF3_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF1">
        <property type="entry name" value="RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23582">
        <property type="entry name" value="WHD_RGF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="904"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1133"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="1366"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="366"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="670"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1213"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="670"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1216"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1724" mass="191127" checksum="B15B82F2A88FDEEB" modified="2023-09-13" version="1">MSYYQGSQYQQQQQPPAHEGYWDQYHRWISTSNGGAQHHYGAEYAQPQDQLHHYPGQSAYGQQPGGGAVQPLPAGYQDTYQSPRGTTFASPQVQQYNPQDYSQATYTQPTQQPAYNPAAYAPVGQGQTPAQYNPAAYPDATLHSSTAGPVDPYAYSPGNHTQASFSPRQPRQVQSPYPQFSPTSQHSGYSPQPQSQSFNYPHSPPPPPPPAHHGYQAQGGAQYGQAAPYPTETYRPHAGSLSQPGASIGIPMPGMTQSDTWRPSPPSHSGFGLGQSPSPRYGSDAPSPRSSSPVPTPPAHGAPSRANTLDRHPSGRPLPPQPARSPGSDYFPNSGMSRTNTGFASVSRDDEVDQLFDEVEGLVRNAGRSPSISISQAPFQAPPYAPAYSSQRGSAASRNGTTNGHLSPVVRHHSGAEAAYSSDSDAEAAKGLAMMQMADEEDRRQSSGSQMRFGTSGSLRTSRPQPPPPPPPPPEGSDSDGPAFAGADLSSFAGYDVPMSYGGEPAQLAAGGEINGEPHSQPASSQHSSMRRSHASQSSQMSRASYDYRSDHIHPFPAFNPAARVEVGGTGGLEEPSATGRRQSYDEGDEYSLMDSQLPDRFPDEPPDISFHQAGTTYPSRPLPAVPYPEDVLAPLQSESKSLPYLPGQVPYPGGPDAYVRDERGQFVPRSSSLVSHSTTPLVTQPLRSKTDAEERRLRQQQARSSMYTTPEVTPEVTPEVTPANVGSDLPALGARRFVPSKLGAPDFKKCDQPWALSHLLKWLLQVTNAEVYTELKEAEVKEALVALFTHKVPTMNIADAEVLSTRVVDDMFVAGTLVVTEEWVKIVPGPFSGVIFQLTQHGCYAPTVHDHLIQSSRCYAPRCQRTLRKINLAAAPRRTSQGWAEYYELKKEDVEGKDKKEVERQNVLHEIVQTEERFMVNLDVLRTLYRDQLTRADPPIISPKRQDKFIQSVFGKVDAVKQANEEHLLPQLKYRQQEQGPWIVGFSDIFRQWVRKARSAYIEYANEFPKADHMVRQEMEINISFREFTMRMSRDERSERLSLDSFLKSPISRLQRYTLLLGTVLRNMKENSQEKADLQLALDEVKAVTLECDGRVAEMQRKIDLTDLGQRLVLRPGMQKEVELNLEHFGRQLIHRGDLQRMGSNRFTWLDCHALLFDHYLVLAKTVAQRVGEGGKTERYDVSRLPIPMDLLQLDSVNEPPVQKSTYLKGLSVGRSATPNDPTTIGRTPSNQAAVPGGLVHVNTSMSTNSLNPVTSLDGKDDRILYPFRIKHLGRDTYQLFALTEQARRDWVDKLIVAKTKHAAALHAQNAEPFRLRVMADSAFVFDQFSNNGKGVNIKGTPVDRAVKEVEHRFKDTGRPGPICRARVNCATSFSTPYPGKQMVAVGTDYGVYVAELNNPRGWTKSINMSRVTQVAVLEEFNLFLLISDRSLIAYHLDVVCPNERNGPTPANDSSRKAPQKLSGSRDVGFFVTGKMKDRTLVFYKKRENLNSVFKVLEPVYQKSTERRSRTAGFLKRGNTEFFREYDDFYIPTECNSINLFQSSLAVGTSRGFEVLSLDKKQPWSVPELKTDHVQNIATTIKDMRPICMLRLSEQEFILCYEKCAVYANKHGEVSRSVVMNFVGNAQHAALYGPYLVLFDNDFVEIRNAQNGRLKQIIAGREVKCLDDGTNWSANGPVEKQANGVVNGFAAGAGRTLKLVMQHPEIDKNQIVVELLLNENMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8R5</accession>
    <name>A0A9Q8P8R5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761542.1">
        <property type="nucleotide sequence ID" value="XM_047905064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8R5"/>
    <dbReference type="GeneID" id="71985794"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05916"/>
    <dbReference type="OMA" id="ILNCHYG"/>
    <dbReference type="OrthoDB" id="5392202at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="31619" checksum="4A5A0854ED46DC0A" modified="2023-09-13" version="1">MSKLSEPLKQFINAAHARPNTVPAPKNVASIYERIAFDAASKKVGLPVWLSASTAATMTMNSPESMLALYNLATSPTHTSSKYPNQPLYAAELMREIGLKCIGFNGVPRTINVLGAFYSSLPAEIQSQLAQRKPRRHLSKSNIEDVLARGDGLWDSIYHPFSHKLSKKLAQSHPDLPVHIIESEYGCLFSDPPGAAGEGIPNVGRVLTSVIAVACLRAQSGVGPQVVSHVFGLRKAFEDGSAEGEEEVPGGRWVAGNEGSLWLLEQVDRIVYGLGEGRGTTYAPGFESAPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8T5</accession>
    <name>A0A9Q8P8T5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Mitochondrial chaperone bcs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_05496</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761931.1">
        <property type="nucleotide sequence ID" value="XM_047904644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8T5"/>
    <dbReference type="GeneID" id="71985374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05496"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="272"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="504"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO17565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="603" mass="66095" checksum="000BBC97C89E5DF9" modified="2023-09-13" version="1">MSAPQIDTRWQQMAGSLVAIAAGIRADSSILDLSPEGIFRNAITLLQQRHSRLAIFLGTTIPLAVLAYAIYDKLGAVFRAFQSLRQLKTFFSPSVTIQFSHPMRFVVLAWLANNSKASPKSMALQTSGSLYEHTSPRNTLEYISHMDETSLRFNGRTFYVTRGSGPVYEEEKLVRPAKDMKISYTSFWGTNNITPIKEFLAMVHSNSTKSKETLFHRVDQDGMGWTQPVGKVPRSMNSIAMATQTKEDLVKDVKSYLSEESKAWYASVGIPHRRGYLFYGPPGCGKSSVASALAGDFKLQVFSIAVSNPALTDDALEALFAQLPDRSLVLLEDVDSAGIERSTPDAKGKSDKKSDPALVCPGRIDMPVLFANANHEIMQQMFAKIFADLPGDSTISSQYDIPKLSQAFAASIPEDKLTPAELQNFLLMHRASPVNAVEKAKAWAETLIETKAQGRNVSHFTGQIGETRPSPTQAAPTTTNTAMAPPAMPEPALSISAMKNGFAMAPGTPTQISPSNTTLVKATQPPTVDEHNPDDDHSSDDESSDDDEENQSPEELKMEIKDLKARLARVKRPLTDYGSTHGGRSLFGRDCMPAPTQQAFHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P912</accession>
    <name>A0A9Q8P912_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-like protein pmt3/smt3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762034.1">
        <property type="nucleotide sequence ID" value="XM_047905663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P912"/>
    <dbReference type="GeneID" id="71986393"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06515"/>
    <dbReference type="OMA" id="CQVEAFE"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12377" checksum="DA05FBEF1DA94C26" modified="2023-09-13" version="1">MDNEQTPPPPVNGADHNGDETNGGPTNDMPAPPKILNVAFKHQNGQELHFKMKTTTKLGKAMDGFASRMQREAGSMRFLLDGERINKDQTFEDLGVDEDCQVEAFEEQIGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P977</accession>
    <name>A0A9Q8P977_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase sdcF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_05908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762229.1">
        <property type="nucleotide sequence ID" value="XM_047905056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P977"/>
    <dbReference type="GeneID" id="71985786"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05908"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040390438" evidence="5">
        <location>
            <begin position="20"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="76"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="368" mass="39402" checksum="E76DFC12A10C0B3C" modified="2023-09-13" version="1">MFALFGMFLLAGAVEFVHSAQEPNNTSQSSSSPHAYPQTKEHSCCQLLANDFAPHLSYSGDATYEQFLNGYWSEASKLQPDCIFTATVGQDVALAIGLLSKSQCKFAVRGGGHTGWSGAANTDTGITFDLSQLNETIVASDRTSVAIGAGARWDDVYDKLDALCLHVAGGRYPTVGVSGFILGGGFSFFSQRYGWGCDTVISFELVMADGTLETISASNKPDLFRALKGGSNNFGIVTAFHLKVFPGGDFLQGVVTYDADHVTSVLTAFAETASTPIEQYDPYSVYLLLFSWQKQADDSVTRSISNWLIHTKVSTSNTTTNTIPPFLSKLAHAAPQLNNTLAIQPLHTFLSSVASQDNPLSPVASSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA38</accession>
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        <lineage>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="20311" checksum="509B6DD3EB8501C7" modified="2023-09-13" version="1">MLQLNYSKYVYQGGDLGGIIFHCQATQFPDDLISGHSNFWLIGLTADDLARYKANQTTVDETTYLNNLENYITNSSGYRKMQQTHPLVLAYALTDLPPGYAMWIYSIMREAVDPSLPDWTADQIITWSLMYLIHDPYAGLRIQKEMLAEGAFAPLEEGGGLLPYVKQPVAISEFPYDLW</sequence>
</entry>
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    <name>A0A9Q8PAF6_PASFU</name>
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
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    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1681" mass="182157" checksum="D1500030D2F245EB" modified="2023-09-13" version="1">MSTSRDGGTRGRGRGTTFNTGASRSSPRGTFGAPSTSGRGGFNTNRGMPNSTFRGNGAPAARGRGRGRGRDQASPFTPKPAMGRARSGLGGAPTTGSWAERQEKLKVRREQEKKDAVAQGLMTDPDKAVALADAITLVGTCQGMCSEYEMVLRVNRNEVFPEEKVNGDPNGEPDESRFVKTFKRSEAGAEAQLPSDLRPPTSLKRTCDYLFNDIIGNASFLGKVHHFVWDRTRAIRNDFSIQQLTKLDDIRIAVECYERIARFHIVSLHQLALAEKPYDKYDAQQEREQLDRTLLSLMQYYDDTRGRLENVNEPEFRAYCVIFAITNPVPDLEDSVQAWPRQLTKDKRVQTALEIYAAACETTYKQGPMAPKAKPVTAQQDWQRFWRLVQSRRVSYLTACVSEIFFNLIREIALKSIIRCTRPARRNPDGSIMNNSELSLEAVADVLQYDDPDDLYSFVARWGLEFQSAEDGTMYLDISYVGGAALPEPKVGPTQQKSFLVERKRHGRTLPAIIDGLSVRQATDRGLVVEEEQEDEMEEVEDAQEEEVETEDEETEEEDNDSLFVGTSKSRQEQNQQTPGSAAAPTPSNPFGLPGTPFGSTPFGQPNRVNGATNPFGSSGFGQPSGTSALGKPPTAINPFKSTEAAKNEVDPASATKPAFGAASDLFGKPAAKENPFAGVFKTNTTAAQANVFTPSTTFGLSADNSQAAPKSSFGAASGFGAPSTTGVSASSAPQAAKPQTPSPIKKGPFEEEGSPTSLSPKKQDFSRSKEASKLPSPTKQTSEGPAAPSLFARSETNSKSAPVSQPPQTAAAPTATSSQPTTSQSIPPGAQSPTKRRSSDIHNKPKRPSPLSNSFTATEDSTTRATQHTESDTARAQSPPPPEKTTDELLTEVADIVTFDPAWGVWKQFVDFQVSQIVAKAQKKVEREIEAAELYRSRAIRVLLQLRDSVRKGRLRAKATAMRERTRRRLRESTASNGSGIATMENSVSSLKASAAASQAQANGVSRGNSDLLRQSTARGRQSHLDGQTQAGSKRSASAYGSDLAASTSSPMHKRQKSMSHVDDQGKVTKPTLSNDTNDDILKRSSFLGFSSRDVQQRANTTKSTYFRMKALGLQGRNRGVDLAASRGTKRERSESLDAASMPPPARPSASTAVASSPDAPSVVSARSVRAKTDEEDDILFARLKALRESLHDGEKVIQEAMAREELRRSLNESQSSNESPSLARARAEARLRASRGNSQSRERDVPAYRLRESRFVPREEYHLAEERARQTRASRDNSRVGSPQGSRAPGVSTNIAGAASARNTASILFNSPPKPARPSKPPPGYGAALPSTTTPSFGFGAPSQAPAVQPTVPDPTTRNPFSQSSSFAPSTNGQNPFLQTFGATNATSFDDFPQDNTLPPSQLNGTLARSFGPPSQAAQNPFAQTTQKSQSPPPPNSYMPSQAASEAISLLSDDEEEPHQPGEEEHQSGHGQNAFLDQTTENDIDGAFAGRSKTVSFDQEAASQALVQGAYNYTNNPFAALADGVADGNKEYEEHYEEEGEDDDQQETAPQPDSYQYSDEQEGEYEGDGTPIDEYSDDEAPNGYIDDEASDAGDIEDEDGDIEDEDGDSGAERPADWNSDQDGHWDFSDGDDDEDDDEPRGFAPLNNAYNQRVMQSAPAKDPALQFVGNTQEEAIELSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAL6</accession>
    <name>A0A9Q8PAL6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the eukaryotic ribosomal protein eS32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763283.1">
        <property type="nucleotide sequence ID" value="XM_047905968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAL6"/>
    <dbReference type="GeneID" id="71986698"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06820"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007836">
        <property type="entry name" value="Ribosomal_eS32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05162">
        <property type="entry name" value="Ribosomal_L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="90" mass="10355" checksum="3D089ADD61E4BF72" modified="2023-09-13" version="1">MRAKWRKKRVRRLKRKRRKTRARSALYDGRTSHTSNLLNSGWDVKGNENGMEQKGNAFMMKGTQMFSLTPAERPPDGRLPLRALEGLAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAN9</accession>
    <name>A0A9Q8PAN9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase family member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763348.1">
        <property type="nucleotide sequence ID" value="XM_047906013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAN9"/>
    <dbReference type="GeneID" id="71986743"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06865"/>
    <dbReference type="OMA" id="WNMFLSK"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF32">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE NM DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="41"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="168"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="282"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="478" mass="53191" checksum="BD4930D7E2ACA76F" modified="2023-09-13" version="1">MSVPYKIEAMEEYLIGGKKRAQRASDRIPMLARVHVSDRAKKALDLVEKFVEEECIPADTVYAQSIGQTTEERFAAHPQVVEDLKKRARELGLWNMFLPKNHFSQGAGFSNLEYGLMAEYLGRSFIASEAVNCSAPDTGNMEVFAKYGTDWQKKRWLEPLLEGKIRSAFLMTEPDVASSDATNINMSLKLEGNEWVINGSKWWSSGAGDKRCEIFIVMGKSDPTNASVYKQQSVVLVPFDAPGITITRMLSVFGFDDAPHGHGQITFNNVRVPKENIVLGPGRGFEVIQGRLGPGRIHHAMRSIGAAERALEFTIARMNDETKKPFGKLLAEHGLMLSRVADARVDIDAARLQVLNAAIMIDTKDAKFALKEIAEAKILIPRIALRIIDEAIQAHGAGGVSQDTPLAKMWTSGRTMRIVDGPDEVHLLQLGRNENKRGKEMLEKIQWQAKKSAEMCLAYGMEKRDPLLLSRQVSKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB82</accession>
    <name>A0A9Q8PB82_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen2</fullName>
            <ecNumber evidence="4">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_07150"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="tRNA-splicing endonuclease subunit Sen2"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
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        <property type="entry name" value="tRNA_splic_SEN2"/>
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    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="tRNA_splic_SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="7">
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            <end position="418"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
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        </location>
    </feature>
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        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
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            <position position="355"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO19232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCW5</accession>
    <name>A0A9Q8PCW5_PASFU</name>
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        <submittedName>
            <fullName evidence="2">THO complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909645.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71990375"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10497"/>
    <dbReference type="OMA" id="EYHTENV"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="208"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO20116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="642" mass="71917" checksum="F6459A02BB1667F0" modified="2023-09-13" version="1">MAATSAAELEPVVRVSARLRALLEHARSVKAETTVEPPLPTTELTTGVEALHDDFDETHEQTTRFLAVETASRQLFYSLITSFQIQQPGFVEVWNLLDIILVCGDHGKCTPELVVWLVEELLDSQTTHGCRTVFDFLDSRRDRLAQKDFHKKNLVFLRSCNELLRRLSRAEDAIFCGRVFFFLFQTFPLGDKSSVNLRGEFHTENTTRFDVTEQSTYGERMDIDPKAGESVGKEATPRGTPQPAGPENLGGKAVPVKAPTKRTAEEEILSSNELYPIFWRLQHDFSDPTRLFNDGNFVLFKKGLASSIAKFQKTATVVQTRSGEDDRRGTKRKMDEDGINPDASEHLVDNYNPKYLTSRDLFELELSDLAFQRHILVQALILIDFLLSLTEQAKKRLVELPTPNKSMLHTFTLSEEDTKWSKSTRTVIADYLRSTADGAQYHRMVETVLARDKNWVRWKIESCPSIVRGPVTTEQELAARKGARSAVRPRVVPDKPNGAMDLSFLDEGTGGGLEVLKDPSRYTAPTIEQLVEAVKTDKLDLDFAADDEEKTSFENAMQNAKWRALRQARSSNLSLLEKDEPGKALEDVMRIPDHVGDEAGEQDGEDAVTAIATSSTAETTESYAKESSMEAEVPPQVAGDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDE6</accession>
    <name>A0A9Q8PDE6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C2H2 finger domain transcription factor CON7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09979</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764756.1">
        <property type="nucleotide sequence ID" value="XM_047909127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDE6"/>
    <dbReference type="GeneID" id="71989857"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09979"/>
    <dbReference type="OrthoDB" id="1939603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="295"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="446" mass="49181" checksum="0F2CE42F9F04FC98" modified="2023-09-13" version="1">MSRGYNTPSTKTNANTNDSSLNALLTSHLQPGPPRQSMDGRQPNYPQSGLDSPYASYNEHQSEGSSADQASAVQYQQPQDYKSSNYSASATPDSSYGLPQSARSGSFPEYIQRSYADGQQQERYPAGAQQSGMAQTSSPSLPMANGQNANNASKNADSDDEVPIDPSIAQSSPSYPHNYSPYPQQQQQQQQHDMPQYAGQPNMQYQRPEWAGQYPQAMSYGHSPATTGGAAPNMVAHAIPRPPAVGTYYGAPPVVYPNVSQGGHPLSTVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGTKRTPEEFKEIRKEWKAKKKEEENQRKAEEERQRQEAQRTGQDTSQSQGQPGQYGQHMMQPQMGGPQLPPIGYQPAGGQPSQYAQAQQVDGAQQYSNNSQMYGAQGYPQSPYGQGGLPYQQQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDP9</accession>
    <name>A0A9Q8PDP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar calcium ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11186</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764888.1">
        <property type="nucleotide sequence ID" value="XM_047910334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDP9"/>
    <dbReference type="GeneID" id="71991064"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11186"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="557"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="210"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="431"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO20522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="585" mass="63262" checksum="5DC0A16337DC6779" modified="2023-09-13" version="1">MHKIKAQARRSAWFNSEGEKTYNPFQRYNPPLRTGVSNDEESGLRQINTHDAITWTEDKRRSQYNAENAPWRGVEKSGTFPPGPAGRLPSGERGDYSSTEKSKSEDIATDNSTTYGEKSRELPAEDIAAAEAASNEHGKPQKRNKFLSAFAKDHPDEQNVMRTETDESKKRRPKLTFMSQVRAVFGSWINILLVAVPVGIALEYSGVNKVVVFVVNFIAIIPLAAVLSYSTEELAMYIGEVLGGLLNATFGNAVELIVSIIALTQGKVLIVQTSLIGSMLSNLLLVLGMCFFLGGVNRTEQHFNITVAQTAASLLALAIGSLIIPTAFRIFADDDSGVTPSSRGTAVMLLAVYACYLIFQLRTHVDMYNEPSQKTPKKPRGKKEDGEALKGIAMIGAASGAATAGGRVNQENLVQEAPEEEEMPALTKLGAVITLAISTVFIALCAEYMVSSINAVADSVSQEFIGLILLPIVGNAAEHATAVTVAIKDKMDLSIGVAVGSSLQIALLVLPVMVLLSWFGVGKPEVLNLDFDGFLVVILVLSIWLVNYLISDGKSHWLEGVMLMITYLIIATTAWFYPAKGEVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV0</accession>
    <name>A0A9Q8PDV0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764977.1">
        <property type="nucleotide sequence ID" value="XM_047910625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV0"/>
    <dbReference type="GeneID" id="71991355"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11477"/>
    <dbReference type="OMA" id="FAGAKHG"/>
    <dbReference type="OrthoDB" id="5399006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26503" checksum="22585025D9D793BE" modified="2023-09-13" version="1">MTTKAIAIIAGVGPGTGAAVARRFSKSYPVVLLARSPENYESLAQEINSSGGKAIGISTDVSSEESVKNAFAAIKKEYGDAPAAAAIFNASGKFVRKGILEQTVEEFHVGHEVSVKGAFIFSQNALPLLLKHVESKDAQYPPTLIFTGATASVKANALMSSFASAKFALRALSTSIAKEFAPKGVHVAHAVIDGVIDIPRTQEWLKDMPPEAKIGAEDIAEAYWNLHTQSKRCFTNEIDIRPMLEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK1</accession>
    <name>A0A9Q8PEK1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765399.1">
        <property type="nucleotide sequence ID" value="XM_047910303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK1"/>
    <dbReference type="GeneID" id="71991033"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11155"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="16016" checksum="C0AF55E5A50F3D65" modified="2023-09-13" version="1">MADDTAKMGGLLQGLPQELKPPHLFQVDRASRYKFAASFFDTVFIFDIAKGATNTQQPIFKWLTAQDPKHLGHLQNIELHLGPQSIAFDASGGHELARSSISRVLREELDLKYSDEAAYRLVDGLTVTWEARTTGEILTIAYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEN0</accession>
    <name>A0A9Q8PEN0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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    </evidence>
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</entry>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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            </authorList>
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        </source>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040251988" evidence="1">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="124" mass="13512" checksum="22F225868EE5A4C8" modified="2023-09-13" version="1">MLGLRTIAISLAAVSSALAVPLENVQQQHKSDAVIQPTDESGDLYRRQFPGLSGADVEIMKDASKAGIWFAEHCAPAIIKANFTGGKPQYDGWKEKFMCPVIAKTFRHLLPFDLPGDLMVPAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFX2</accession>
    <name>A0A9Q8PFX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoskeletal protein syp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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                <person name="Stergiopoulos I."/>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
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            <dbReference type="PubMed" id="35471194"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="WGS project CABT00000000 data, contig 2.23"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="640"/>
            <end position="904"/>
        </location>
    </feature>
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        <location>
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            <end position="467"/>
        </location>
    </feature>
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            <end position="150"/>
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            <begin position="241"/>
            <end position="270"/>
        </location>
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            <end position="318"/>
        </location>
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            <end position="408"/>
        </location>
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        <location>
            <begin position="621"/>
            <end position="633"/>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG79</accession>
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        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-mannitol + NADP(+) = D-fructose + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16765"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16899"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
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        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:16766"/>
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        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:16767"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF1">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="275" mass="29548" checksum="EC21B7669CA2DBA5" modified="2023-09-13" version="1">MSMSLEDVAAQPREPRPFPNTPSNVLEQFNMKGKVVAVTGASEGIGFAVAEAIAEAGGDVALIYNSNPAAHEKAKQLTQQHGVRAAAYQLEISNPAKVEEVVNKIASDFGRLDVFVANSGAAISKPILEMSIEEYRHLVSVNFDGTFFCAKYAGAIFKKQGFGNLIINASISAHIVNVPVDQPVYNATKAGILHLGKSLAREWREFARVNIVSPGFFDTKLGAAPKVQNEAYRMAVLGRQGHTKEIKGLFLYLASDASSYQTGSDTIIDGGYTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG80</accession>
    <name>A0A9Q8PG80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent monooxygenase OpS4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766193.1">
        <property type="nucleotide sequence ID" value="XM_047908012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG80"/>
    <dbReference type="GeneID" id="71988742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08864"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF316">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="43551" checksum="A36E7C1C86D5F876" modified="2023-09-13" version="1">MTDYLSNVAIIGAGLGGCALAVALSERKIPVTLFEARPEITEGIPSGVILPPNGLRILDRLGIFQRIRDPCYIPTDRVFKNDQDETTKKLPVGGVERWGYRNHRVWRGILLDEMKAILKERNVTIHYESRFQGIVSDTAKEVTFRVNNETIHASMLFGSDGINSSIRQYIAPGVEPEYTGLTAVLGHIKWSNVDWPYPDYEHNATIQSKPGAILWIAEDSEAKHTPKHSREELAKLQADPDQLAAFYTENYDEYGPTARKIIDAVCKRKESLFIWPFMKMPKLERWYSETGRVVLVGNGAHALPPSSGQGVNQALEDVYFITLLLSSLDGTPSSTGQTTRPTRLPEAERQKVLAEGKVKTDQEEDMDWLYQPNIDEKVDVWLQKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG94</accession>
    <name>A0A9Q8PG94_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08893</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766240.1">
        <property type="nucleotide sequence ID" value="XM_047908041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG94"/>
    <dbReference type="GeneID" id="71988771"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08893"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="74"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="29239" checksum="6AC2CAA92513C99B" modified="2023-09-13" version="1">MDDSNNHNTTTTNNFDLTMANNSSSEDEDLGAAFAKATADKPDSRAATRKKNNVVVPVAAPEADGAKKISAHVYGHNKLIPGQWFASRASASTTWNAHEPTPSNVHPGPEGAFSIIVIYDEHGDLNEDLDGGTTILFASTGASTWKKHRKTLKNDATVALDASIASKKPVPVLRAAPKAKMGGKKSEEVLYPTQGLRYDGLYRVVSAMRGEINLGTNGKYDAYCLKRLPIVDEVVKVKKAENQYAQLELKVSIPRCEQGYGGYVEGPPKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGH0</accession>
    <name>A0A9Q8PGH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766346.1">
        <property type="nucleotide sequence ID" value="XM_047908103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGH0"/>
    <dbReference type="GeneID" id="71988833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08955"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="307" mass="32572" checksum="FB129E9509704C84" modified="2023-09-13" version="1">MSQPTRTYGDNGGSVATHPSHSVVYIPVTYIPPAAAAQPEQTTSSSTLAPIAATSQQSSFALVPIQATSAQDTASTTNNNAAEISTITPPQPMVLVPLSALPPPTLTPKRTYDLVFVVTPGKKRTYHRELQLNGHPIYTIERDKPYFKARQLNFLDSQTREYLAGVRLGHWNRKVSICLGNPYQNEAYVKIYQEPQFNYQGRGYEWQMIESTQTRTLIEMGQNDGKVLARWKVDEGVGTVQWMVIPERTFEVWCLAANFALTEARHSSIGGNGAGGCGGGPCGGSGGGGGGGGGGGGGGGCSGCGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGQ4</accession>
    <name>A0A9Q8PGQ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-coenzyme A thioesterase 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766534.1">
        <property type="nucleotide sequence ID" value="XM_047908736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGQ4"/>
    <dbReference type="GeneID" id="71989466"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09588"/>
    <dbReference type="OrthoDB" id="46529at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000033">
        <property type="entry name" value="acyl-coenzyme A thioesterase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF11">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04355)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="74"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="170" mass="18258" checksum="C8070914AD30A15D" modified="2023-09-13" version="1">MLSQGVHAVPDSDLTSIMSKTQEHQHIEHLVETKLPTSPIYKFLLTPVNITSATKGHVVARLPLSEDHLNSQQSLHGSVTATIVDWMGGMAISSYDLRAGSGVSIDIHVTYQSGAKAGEEIEIEGIAERVGGSLAFTKINIFKVEDGKRGKVVATGTHTKFVKGSEPKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ54</accession>
    <name>A0A9Q8PJ54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxysterol-binding protein-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767877.1">
        <property type="nucleotide sequence ID" value="XM_047911862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ54"/>
    <dbReference type="GeneID" id="71992592"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12714"/>
    <dbReference type="OMA" id="WNYLDAP"/>
    <dbReference type="OrthoDB" id="48057at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF212">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="467" mass="52507" checksum="B762C774721A71E2" modified="2023-09-13" version="1">MVFGHSKKTSVAVLDSPATSTTSEPSSTTHSADNSAKTSMDSNGTPIKAKEELAQAAAVDGQTPSDTSKLKTFLGILRRFVGVTDMAAVRFSLPAQLMEPIPNLEYWHYLDRPETFAAIGDAEDPLERMLGCLRFWFTKDLKYVKGKPCKPYNSSLGEFFRCTWEVEDQKGQDNKPLKVNYITEQTSHHPPVSAFAYDCPEKGVEAMGYDQLSAKFTGTSIKVTPGQYNQGIFIRLKNRDNEEYKLTHPAAFLGGFLRGNLSITVADTCYVECEKTGLKTILHYLEEGYFGKTQNKVEGVIYKSDSIASDNITRLKDVPTKQILGRIEGVWTEKIYFTSGATEFKKVAEKDRVLVMDVTPLLPIAKKCPPLEQQLPNESRRFWNDVTEFITSKQFAQATTRKQQLEERQRERAAEREKAGEKWQPRFFTTVTESSGKAVLSEEGKRAMEGLQKEEYVLKEPESYGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKF7</accession>
    <name>A0A9Q8PKF7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768501.1">
        <property type="nucleotide sequence ID" value="XM_047912279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKF7"/>
    <dbReference type="GeneID" id="71993009"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13131"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="35161" checksum="7F9DBD73C87DEE8D" modified="2023-09-13" version="1">MFGHEQRLRISRELVEMLRNLRDVVESRLLWIDALCINQADEKERYSQILLVGDIYRHASKVLLCYGKGDSTIEHEDCASVDGRWPWVGYIDIRSAITCLRGRPWRLSWLLEKAACLDMWTDVRYKQVSGQDSMSWESQPPMKRAILKPGILMFTPIPLLVIRDYATARDLGPKIPMYLRQSSDSDTWSSRVAAQKYWIVEPPPEMFAAATMTFIILLTWHRGLNERYPVQSKIMVTSVAGGILLGALLDLSVCASMLNLVPIAAYLAAIASELIIVASSKKNTMKDSSESRLWRVDEKLFHIEAKDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLC1</accession>
    <name>A0A9Q8PLC1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769002.1">
        <property type="nucleotide sequence ID" value="XM_047913139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLC1"/>
    <dbReference type="GeneID" id="71993869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13991"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
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    </dbReference>
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        <location>
            <begin position="18"/>
            <end position="354"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
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            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO24636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="38503" checksum="7A476EC4A8886946" modified="2023-09-13" version="1">MAASIPKTMQAWRYRFENTEPHLAEAPVPVPAADGLLVKVLAMGVCHSDCTLLGMNEPILGMRPEFTMGHEACGEIVQLGSDVDKSAFAIGDKIVMLIIPGCGKQTCPDCSRGFTTICRSPDSGNYGLGISDGFFAEYVTVAQRAAVKVPEGLDLASAAVSADAVLTAYQAIKDTGNPQPDHTIAIFGLGGVGLNGLQTALHMGVKNLLVADKRQASLDEAIKLGVPKSHTFLVGEGTPIEQYVAEQQLQVDMAFDFAGHEQTFQAAQMVVRNAGTIVLVGLFSPTVPLIPLVSVLKAVTIKCHYNGDIKGLRECLELVGKGVLKPVVETGSIRDLPRVLKDLDEGRVRNRMVLLPDWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLF3</accession>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="154" mass="18171" checksum="0B84585E16B9589F" modified="2023-09-13" version="1">MAQQGASKDTWKCRLLSLPAEMENKIYRYTLTTPEDIEIRSAADLPVGPGLLRTCRQIRPEAIGIYYHENDFAFPIQNFNADCYIKFCKSSRNRLMSSHIFRIYEARTGSWPNLVRWLKAWWDYECRSLEPPEKERRQGDTLCCPLVRYRPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLI5</accession>
    <name>A0A9Q8PLI5_PASFU</name>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
    <dbReference type="GO" id="GO:1990072">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="19"/>
            <end position="199"/>
        </location>
    </feature>
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        <location>
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            <end position="323"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF23647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="327" mass="35272" checksum="AE09F741CA93FD91" modified="2023-09-13" version="1">MATSPSHTRTRSNTVTGPHSVSLKVLRLSRPSLATQTPLPATNFGDGLDISPKASVAYPTSDEAHQHGAFPLTPLLTLPAAFGAAYVGETFTCTLCANNELPTDTSNKTVSGVKIAAELQTPSHPDGIALQLEKAGKAEDGDDGGDVQPGGTLQRTLGHDLKDEGPHVLAVTVTYTETLHGNGAASGGRARTFRKLYQFLSQQLVAVRSKVTERKKRDKDSAGPREWVLEAQVENVGETSVVVEKVKLKEREGITSREMMNGEEGREALVLKPQDVEQVMFILKEETEQKDEEVGVRVPLGQLHIDWRSAMGEKGSLTTGWLSSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLK5</accession>
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    <reference evidence="2" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    <dbReference type="GeneID" id="71993759"/>
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    <dbReference type="OMA" id="GHTCHDE"/>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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            <begin position="189"/>
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        <location>
            <begin position="165"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="32839" checksum="C2F2D6AF31D15365" modified="2023-09-13" version="1">MSPPANAAAVAKVLADIDADPGKIASRSQQDSFLKNMTSKYKFRYYSSTYGHTCHDEKSLRSVLVAIMRHHGKDGEDIRPGKSAVDELFERGSGMLDDDYLKAMTEAAEGIELEVDSDSDDSEEESEIDQELIDFIEAQTDSDDEYTPNLAGRTRSANKKRRLSATVQDARQHQKTSLIESWIESCSTENSGRHTSTLNDDQNAGTLGSSSGTSSIAVAKRRKTGLSSIHHRTSKAQTHTQTIKHVATKSSKPTDAPEFLGLNENTDTLDTATRKATLRGTRDDGLLHIKLLAVAAIAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM35</accession>
    <name>A0A9Q8PM35_PASFU</name>
    <protein>
        <submittedName>
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    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14446</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM35"/>
    <dbReference type="GeneID" id="71994324"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14446"/>
    <dbReference type="OMA" id="HERACRR"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
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        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="50"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="29465" checksum="41CE09093AE94ADA" modified="2023-09-13" version="1">MASTTSTAGNDWSVHAQQYAKHITSFTGKGAAALVAFVNEYAPLSLSSKVLDEGAGTGIMTEMLVAQHPGITVTAADIAPGMLEILDQQKLPNVSTKVVDAAADHQAQGLVPKSYSHVLSSFLVQFVNPGQAAVNEMFRMLQPGGTLGIATWEVLSMGEPWLIACKNLDPNFTFSTPFKSFNNATSLENALQEAGCMDIHSTSADIWWEPDSVEHFVEVFMDSQNPAYVVMQEAFHGDREEARAEMTKVVRERYADLRFYLKAVCVVGKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM48</accession>
    <name>A0A9Q8PM48_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM48"/>
    <dbReference type="GeneID" id="71994212"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14334"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="61" mass="6262" checksum="6BF4DB42D3284A73" modified="2023-09-13" version="1">MANSLFSPHGKAGPIRSTAPLLIGLGIGGGFLYWLRFQGTHKGDVTKKVPPKASGPMGGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM81</accession>
    <name>A0A9Q8PM81_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Annexin C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM81"/>
    <dbReference type="GeneID" id="71994256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14378"/>
    <dbReference type="OrthoDB" id="2134400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF107">
        <property type="entry name" value="ANNEXIN ANXC4 (AFU_ORTHOLOGUE AFUA_3G07020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0041">Annexin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="726" mass="81555" checksum="95C2555891EE0045" modified="2023-09-13" version="1">MSFLGSDRSRKGRGRSKSPSGRDGRDRSRSRGNVRAPEAPEPPAAVPRSASYGYPPTSSTMPGAVQDGVTSPAYDVRAPQKAQSNYYPQPSGPPLPYGPGATAMPSMPYPEEDGGFTMGAYTDLPPHERPGYDPRLGYVPHPGQRGQRDSSSSDEDLAYGADTSRRDDRSRQTSSSNRYKYTPDNVRNPSGQFEYAKAPEKIQYKPSAGQGPKSPASYSSQPYGQPPQQPLNYSSNTYGRPEPLPRTFSNGQPSHRYSQSGYDNGAQVVDITPGGGRGKLDRHNSSSERVTRLSTPEPHGRQHSASLSAPGLGPRMDRLSVSGNRPDLSGLGGGMPPPSPLLEAYHGTYQSISPLPFDIRGNDDLSDMDDLDLNSGYARAGQQRNDRLAQDLRAQEKKAKKSVKLYDPEEDAKTIASALSHHKVDADAICDTLPRLSHDQIVTMRKEYKKQVKVQGKGVNLSKHINMKLSGNFGKAVYVTALGRWESEGYWANFFYQSHGSRRELLIESLMGRTNAEIRMIKDEFKDKRYSDSLMKCMEKELKMDKFRTAILMALEERRQEEQDVYPQEYVLRDVDMLYRSVTAQKGGESPMLEIIVRRSDAHLKEVLRMYEGMYKENFARTALRKSNNLVGEIIAHILNGVINRPARDALLLQHAIKDIADRNRDDELRYELLVSRLVRIHWDKAHLQRVKKEYWEKYRSTLEDAIEEAMKGDFREFMCELCETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMH3</accession>
    <name>A0A9Q8PMH3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS siderochrome iron transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_14322</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769715.1">
        <property type="nucleotide sequence ID" value="XM_047913470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMH3"/>
    <dbReference type="GeneID" id="71994200"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14322"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="550"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="91"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO25349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="577" mass="63030" checksum="A09133555E00D62B" modified="2023-09-13" version="1">MPSEASSRPAQLRLQQFDSDPEYRPLLAPHPRTRGMEKTDSGSEPPRASTSKAPVDLNSIVEEGTTLFERKCLLINAEIDNNGMGRYQWSIWFLCGFGYFLDLLWAQAFGLVLSPLEQELGFAGNQSGNISIAFSAGLTAGAFVWGVLVDIIGRKWAFNITCLIGAAFGLGLGGCNTYSSFLVITAFVGFGIGGNIPIDTTICLEFIPQNKRFMLALLSIFQPIGVVVCCIIAYGFIPTYSCEPNFTQGDRALPSCKNVPSGQACCTRSSNMGWRYLMFTIGGITLAVFFLRFVVFNFKESPKFLVYRGQDAKAVEVLEHIAKTNKRPCGVTLADFEALDQADAMRTDGMRHTEGPSTFNGKFRAEMLRYGSLVQDWRMTRLTILVWLTYAFDYWGFTLAGTYLPSILAIKNGALDLSLRHTYRSYIAIYAPGIVGVVLGAMMYGVPAIGRKWTMVISSALMGISIFLFSTVNSEASNIGLNVMEYFFQSMFNSVLYGWTPEVFAAPIRGTASGVASFWGRLFSILAPLTAQSVIPAGGLSVENGSINEVLYLAGGLTMGAVITTALLPNRLGKQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMM2</accession>
    <name>A0A9Q8PMM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-binding monooxygenase moxY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769586.1">
        <property type="nucleotide sequence ID" value="XM_047913309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMM2"/>
    <dbReference type="GeneID" id="71994039"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14161"/>
    <dbReference type="OMA" id="MVFHTEV"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF1">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE STCW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="635" mass="72929" checksum="9AE7BD66C9E54FFF" modified="2023-09-13" version="1">MPPFLNGHGEADFKIPPPGFSPPKRHQRNQQPVDYSTPGSTGYNVPQNTTWRDPNNREIRVLTIGAGISGILMAYQLQKHCENVEHVVYEKNEDIGGTWYNNRYPNCGCDIPSHAYTYQFALNPDWPRFFSFAPDIWAYLNKVCETFDLKKHMKFHVEVVGCYWQEHAGEWVVKLREHLPNHEVREFEDRCNMLLYGAGVLNNFKFPDITGLQDRFKGRVIHTARWPKDYKEEDWAKERVAVIGSGASSIQTVPGMQPHAKHLDIFVRTGVWFGVIAGNSGSQAKEYSEEERETFRRDPKAVVAHAREIEEQVNGMWGGFYAGSMGQKMGSEYFRKRMAEHIKDERLLQGFSPKFGLGCRRITPGDPYMQAIQKENVDVHFTPVESCTEKGVVGGDGVEREVDTIICATGFDVSYRPRFPVVGKNGVDLREKWEDLCPESYLGLAIPDMPNFLTFIGPTWPIENGSVMAPLHSVSEYAIQLVKRMQNENIRSWVPRQDITDSFNDHVQEWIKHTVWKNDCRSWYKNNETGRVNAIWPGSSLHYQQVIETPRYEDFEIHSFNDNPWAHLGMGWTVQDRKGPKEEDVCPYFNVKNIDPKWYEACGGDARLLSERPQPDILEQETAQAGQQFLWPTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMP7</accession>
    <name>A0A9Q8PMP7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Averufin oxidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769570.1">
        <property type="nucleotide sequence ID" value="XM_047913310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMP7"/>
    <dbReference type="GeneID" id="71994040"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14162"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="292" mass="31913" checksum="C9AF641C7EA8C466" modified="2023-09-13" version="1">MPTYALLGATGATGSSVLRCLLAAPPPDLELNILVRSKSKLLKPFPSLANRTDFAIRIVEGASTNTAALQQCLEDADVAFMCVADNASSKGVSITYDTASAMITTLTMLRKLQASDYSPPTILQLRSASLNPKLSCQVPRFVYNMVSFCLHYNHLDVVRACELYDAAADDNLLEYIYVDPPTIHDAFGTNRTGHKLIPCNVPVCAKQETALSYADLGASFVEIAERRHEFANQPVGVTATGKVKETWGVLAGYLFDGARGRVNAWMEERRTKAWMSDKKAIKTANLFLYCGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ68</accession>
    <name>A0A9Q8UQ68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762948.1">
        <property type="nucleotide sequence ID" value="XM_047906678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQ68"/>
    <dbReference type="GeneID" id="71987408"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07530"/>
    <dbReference type="OrthoDB" id="10588095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32300" checksum="007B06A7E1F7A094" modified="2023-09-13" version="1">MANPSQALTILFCKELSTLLSTASNNDAIRLLPDKTWLLSSVLAIHVSIELGDVLEALDAKASSSTLIHGYWHEEQDSVYVLMGQDVWQSTRCDRHAGSRVMTMVNNDPLDSVKRMQVIKLHTVPAEPGPCPGAMEHNGTELQVLAHFLRASLRLNPFDLSIVVTALAEGSLSLTPSFEGVSRHTSAALLTTARSALLHASTYKHLLSGAVRSTPSLVQLAEIYDISAADRPLQGIYTIMVQFSGAPAAEALRRRQPSFLHGLAHLAWRHRPCAHPRHTGLHEAILHACQLYAPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQJ8</accession>
    <name>A0A9Q8UQJ8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="18908" checksum="41DFB01F3D166196" modified="2023-09-13" version="1">MDWSETDEDNEDDGSQAGSDAFRDTAQSIGEDEVGEAWTYRYLLRKAKKTISSTGEVQKQKMQRGEQRRRQDDEDTDGGEDHGRYEEDTESETVSELPRLRTQFRSIRDRKPGGLNVGLLRNAFLLIDQDSIDSLITNPAALAWGSPEEYRGYLRVRVQQEVNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP4</accession>
    <name>A0A9Q8UQP4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP4"/>
    <dbReference type="GeneID" id="71987534"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07656"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="33"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="28507" checksum="17D299CA48C77AD0" modified="2023-09-13" version="1">MPNPLPRFLRCVHDLCHKLQRARCADECYLLALPAELRNMIWHFACTDAPHIEIGTRQIPATLIICKQMREEMYLMYYALGCYAYTDHGHLRQGGQDDTASISRWLADMRINQKEITHLELRLDGSSRVMPRTFSQHQRNTLPNLLLPEIRWIWHIDNAAQESAEGLIYSIWSSQVPIKTVAIELPFTESKMTRKEFRFRWRWAIELFYRLGERLPDTIFVAAGGTTHTVSFLRAIQIVYLTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR70</accession>
    <name>A0A9Q8UR70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADPH--cytochrome P450 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763814.1">
        <property type="nucleotide sequence ID" value="XM_047905984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR70"/>
    <dbReference type="GeneID" id="71986714"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06836"/>
    <dbReference type="OMA" id="ADIVIFW"/>
    <dbReference type="OrthoDB" id="3633599at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF108">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="93"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="280" mass="30896" checksum="2FF34F45D882F5CA" modified="2023-09-13" version="1">MEMNNIQLPALSLVSIEKVFSVLPRHISLDDVVAVAAVTAVLWTLWYLGLLFERSDPHAYKMYERPQEKMGAIGGAKGTRNGAEKLDQIGADIVIFWGSQSGTAERFANRLSKEIRQRFGKKALAADVSDYETTFIGEIPETKLAIFVVSTFGEGDPSDNLQDSWSWLETAKGSPFANLKYAALGLGNSNYKYYNAVVDVVAAKLNALGAKCLLPVAYADDAQGQTEEHYLEFKANVFQHFKTSMDLEEYDPVYEPLLQVVEDTSLEPIAVRGRALGSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URX3</accession>
    <name>A0A9Q8URX3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764625.1">
        <property type="nucleotide sequence ID" value="XM_047909720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URX3"/>
    <dbReference type="GeneID" id="71990450"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10572"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="20628" checksum="9B6B0C2B961014FC" modified="2023-09-13" version="1">MRTVARWSGATLPCACSMFTTLESKEQAEFHGHHPLHRITSSRRIASLVRETFRDDVQGCTRMYKDVLKKRRRELDGVRKVKEFCTFIKEGNVDVEWFWIDTCCIDKRSSTDCLIERAWTLQMLLAPTTVLFVINNRDWEIIGHKGRMAGLVGSEKDLTNEIAEITGMRKPVPLLLNVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US03</accession>
    <name>A0A9Q8US03_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764715.1">
        <property type="nucleotide sequence ID" value="XM_047909218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US03"/>
    <dbReference type="GeneID" id="71989948"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10070"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415:SF3">
        <property type="entry name" value="GNAT-FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415">
        <property type="entry name" value="SPERMIDINE N(1)-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="197" mass="22464" checksum="141AC66CBCD96B1E" modified="2023-09-13" version="1">MADPFRSKRLLYRAPESPEDEPFFLGIQQDSLGYQNSNISIPRPQGKGSMLGVVICLPPDDDCERSEAEGKKRSSTPIGAIKLSAYPARMMHHRFSEIGIDIDQEHQGRGYGSQAILWCLGWAFERAGLHRVLIRAFEWNEGAVRLPRRLGFVEEERGREALWFEGRWWDDVSFGILEGEWRVMKGRGSRGESRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTX0</accession>
    <name>A0A9Q8UTX0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Alternative oxidase</fullName>
            <ecNumber evidence="17">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_09011</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 17">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="16 17">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the alternative oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="17"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766619.1">
        <property type="nucleotide sequence ID" value="XM_047908159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTX0"/>
    <dbReference type="GeneID" id="71988889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09011"/>
    <dbReference type="OrthoDB" id="16906at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.140:FF:000002">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="14 17 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="313"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005229-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO22253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="342" mass="39087" checksum="61F032B9C8316414" modified="2023-09-13" version="1">MNCSRTVSTSTLLTKQSAAQVLKALNGSTTVAYSRPAFLGLQQQWTARSFSTSKPTQWKEFFPKPDAPSIRETKPAWEHPVYTEEQMKQVEVAHREAKTLSDKVAVGFVRTLRWGLDIASGYTKNSGGMTERKYMIRNIFLESVAGVPGMVAGMLRHLRSMRTMKRDNGWMESLLEESYNERMHLLTFLKMAEPGWFMRLAVLGAQGVFFNAFFVSYLISPKTCHRFVGYLEEEAVLTYTREIEDIDAGRLPMWSKMEAPDIAVKYWNMPEGHRTMRDLLLYIRADESKHREVNHTLGNLDQANDPNPYVSTYKDPSVPHPGKGLEHQRPTGWEREDVIGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU28</accession>
    <name>A0A9Q8UU28_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12456</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766831.1">
        <property type="nucleotide sequence ID" value="XM_047911604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU28"/>
    <dbReference type="GeneID" id="71992334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12456"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 11 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="24762" checksum="2D0E8213CFAA93D1" modified="2023-09-13" version="1">MINQTGMLGEDGIHIDMNHLKSGEVNLGTSIMAINFADGVILGADSRTTTGAYIANRVTDKLTQVHDTIWCCRSGSAADTQAVADIVQYHLGMYGITNDEHPTTQTAAAIFQELCYDNKDALSAGIIIAGWDQRHGGQVYSIPLGGSLHKQAYAIGGSGSTYIYGYCDANWKEGMNEQEGISFVKGALQEAIKWDGSSGGVIRMVVLTKAGAVRHLYLPDRNYTGPGTEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVP1</accession>
    <name>A0A9Q8UVP1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-fucosidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768438.1">
        <property type="nucleotide sequence ID" value="XM_047911891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVP1"/>
    <dbReference type="GeneID" id="71992621"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12743"/>
    <dbReference type="OrthoDB" id="2848340at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054363">
        <property type="entry name" value="GH95_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084:SF3">
        <property type="entry name" value="ALPHA-FUCOSIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22124">
        <property type="entry name" value="Glyco_hydro_95_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 95 catalytic" evidence="1">
        <location>
            <begin position="9"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11426" checksum="5F7969DBF100E29C" modified="2023-09-13" version="1">MILNEPNHDFLTTLTVSSHLDTGLHIGSFNHIQEWKLPLDTPNDTHRHISHLIGWYPGFSIASYANGYTNSTIQSAVRTSLVNRGIGITDANSGREKVWRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW05</accession>
    <name>A0A9Q8UW05_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768887.1">
        <property type="nucleotide sequence ID" value="XM_047912990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW05"/>
    <dbReference type="GeneID" id="71993720"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13842"/>
    <dbReference type="OrthoDB" id="5372451at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="614" mass="67897" checksum="6FCAED77263715BD" modified="2023-09-13" version="1">MPGVVSGSSWDSILTLLRTTGRIALFNLPALEIDTDVDGLFVIRGVTFSLSSFTLVAHGIELGLKLTDDIELAMYVDEVVVQFFRSIDVGDVYANVKGGKFEMTLGDLDLTADDDASSETSVFLDDTPLLRAATAGSRGFTDRPMLRESLTGGVKTMRDSSAQAGFNMVESLSPDDNIADKQYHERLTEIRTTSAVYQSRQQVRQKAKGENGFKFDNENDMRAAVSAELHKLPSIPHPPNRSVRVTTLQTLAPPYVRSFLHRLPFLLRLLLAPLSYFHPISISSITGNGSGQWLSALLQQQVFKHHTEHNAELRRIHRRISHWLADANFCMQFTDVSGLGQVPLSTLFDIVAYLKFSDVMAYRTEPEKNTIRQVVRLGGADATFTIPSYLLPHHEHIIPAEPTPQEEHELRIEVEQADGLPHEVQKEKELEKLQKDETNITMSVHASLPLSCDQTVLNFVAALVKATKMIEAEKEVEVIEQTSGKEQETPASPLSRSSTADNDKDSLRSRSDSKDASGFKTFAKNIRQNLKDGTTGTQIKEFAKELHQNTKDGLEKTKRTMVAGMVNDRWIAKIVGKTAAMLQKAQGDVGYSGGIPVPLAPYRGSASLPSKILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWB0</accession>
    <name>A0A9Q8UWB0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme E2 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_13925</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769083.1">
        <property type="nucleotide sequence ID" value="XM_047913073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWB0"/>
    <dbReference type="GeneID" id="71993803"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13925"/>
    <dbReference type="OMA" id="TWECGIP"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019789">
        <property type="term" value="F:SUMO transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO24717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17860" checksum="B00E6813203A3E7E" modified="2023-09-13" version="1">MSLTVARLQEERKQWRKDHPFGFVARPVKSSQGALDLKKWDCAIPGKDKTIWEGGLFKLEVQFPDEFPTKPPKCKFVPPLFHPNVYPSGTVCLSILNEEEGWKPAITIKEILLGIQMLLDEVNPDSPAQADAYNLFKKDRAAYEKRIKQVVKDNPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWC4</accession>
    <name>A0A9Q8UWC4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769128.1">
        <property type="nucleotide sequence ID" value="XM_047912935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWC4"/>
    <dbReference type="GeneID" id="71993665"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13787"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="16"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="393" mass="43323" checksum="1824865404761B45" modified="2023-09-13" version="1">MAPMARFKQTGAAKRQPYEVKGSPGKGNGVLATRAIEPGTVIMKDKVAILIKKDPPTVQPTDVIKAVASLSTSDQARFFALHEGSRPYSSQAFRIYKANAFGSKGESRLFLKISLINHSCVPNAEISDSNKDDDDTDHVFAIKHIATGEEIFINYIGQSETMIRGHRQTVARIYYGFLCSCTACRLPGQEQQLSDRRRQLIAVLSNALEGFQPPIARYFDGLARLTPEQAEDPRVLNGIPRFPLSSALTLQQKTAYHALLGHLLVAENFAGFKVATAFSNAAETLVHQMDQLVESHMLVYPTSTRLATLWMGKALQIMDSARGQASEEYKYIAQTWEFMKESNPMIAGMLYASKVTRGKEGSYALRVIERGGGAVEMKELTEAEAKGVVRGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWE9</accession>
    <name>A0A9Q8UWE9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sterigmatocystin biosynthesis protein stcT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769350.1">
        <property type="nucleotide sequence ID" value="XM_047913525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE9"/>
    <dbReference type="GeneID" id="71994255"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14377"/>
    <dbReference type="OMA" id="MAIALYI"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000142">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="87"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="26306" checksum="FD888076E70C5997" modified="2023-09-13" version="1">MSFGTVYTRDGNPRTVSIRAIAAADNLDISYQFVQGAKEAGAEYLALNPLGKVPTLVRSDGFVLTETLAINLYLAQQNPKTTLLGSSLEEYATIIRWMSFVNNDVYDVLGGWFLPLIGRRPYVKESVLEHIELTEKRLRMIENQLGKSRYLAGEKLTLADLFVCGLLAAGFQCFFGREWRESHPEFTRWSRDVYHQEIYQMALAPEKRGKLFEIEVALPNEPFEDPTKFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWS1</accession>
    <name>A0A9Q8UWS1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Malic acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769682.1">
        <property type="nucleotide sequence ID" value="XM_047913630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWS1"/>
    <dbReference type="GeneID" id="71994360"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14482"/>
    <dbReference type="OMA" id="IFPCMIC"/>
    <dbReference type="OrthoDB" id="2901184at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO25316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="49030" checksum="0F0763D3D32AFF01" modified="2023-09-13" version="1">MPNEQHLFWQRYLPSTNPSRATSALPSRAGSQVNLNDTEKLKHLDGIDLRLPVPDDLSYLVPTRERIKHFTWAWFTLPMSTGGLALPLHNTPNRFPGLETIGKVVYIFDLVIFLSLCAMMATRFIMNPGALKKSLMHPTESLFFATFFLAFVSVVSCMQIYGGPSTGPWLTVVVRVLFWIYVAATFTTAVSQYLVLFSAKRLTIQSMTPGWVLPIFPIMLTVSQREAIIVAGITFQGLGWMVAFMVYAIYMHRLMQFGLPAPNLRPGMFIAVGPPSFTGLALIGLSQALHEDMGDFQARPGIIIVLQTMADFIAIFLWCLSLWFFCIAMLSVLGGVKKMTFHLAWWAFVFPNVGFTIATIRIGEQLGSEGILWVASIMTILLVAMWIFVLVAHVRAVWMRQIMMPGVDEDKEDYKANDRKNDIPVPPDHQRRTMR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-12-05" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>P0CU70</accession>
    <accession>A0A9Q8UUZ9</accession>
    <name>CLAM_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase claM</fullName>
            <ecNumber evidence="6">1.14.13.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cladofulvin biosynthesis cluster protein M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">claM</name>
        <name type="ORF">Clafu184398</name>
        <name type="ORF">CLAFUR5_12902</name>
    </gene>
    <organism>
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2014" name="Mol. Microbiol." volume="92" first="10" last="27">
            <title>Functional analysis of the conserved transcriptional regulator CfWor1 in Cladosporium fulvum reveals diverse roles in the virulence of plant pathogenic fungi.</title>
            <authorList>
                <person name="Okmen B."/>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="van der Burgt A."/>
                <person name="Cox R."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24521437"/>
            <dbReference type="DOI" id="10.1111/mmi.12535"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2016" name="Proc. Natl. Acad. Sci. U.S.A." volume="113" first="6851" last="6856">
            <title>Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Saccomanno B."/>
                <person name="Vaisberg A."/>
                <person name="De Wit P.J."/>
                <person name="Cox R."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27274078"/>
            <dbReference type="DOI" id="10.1073/pnas.1603528113"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2014" name="PLoS ONE" volume="9" first="E85877" last="E85877">
            <title>Secondary metabolism and biotrophic lifestyle in the tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="Iida Y."/>
                <person name="Karimi Jashni M."/>
                <person name="Battaglia E."/>
                <person name="Cox R.J."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24465762"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0085877"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2018" name="Mol. Plant Pathol." volume="19" first="369" last="380">
            <title>Down-regulation of cladofulvin biosynthesis is required for biotrophic growth of Cladosporium fulvum on tomato.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Overdijk E.J.R."/>
                <person name="Saccomanno B."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27997759"/>
            <dbReference type="DOI" id="10.1111/mpp.12527"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="4 6">Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:24465762, PubMed:27274078). The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG. The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078). This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078). The cytochrome monooxygenase P450 claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 nataloe emodin + reduced [NADPH--hemoprotein reductase] + O2 = cladofulvin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:64288"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:152055"/>
            <dbReference type="ChEBI" id="CHEBI:152057"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:64289"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Pigment biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="4 5 6 7">Expression is positively regulated by the transcriptional regulator wor1 (PubMed:24521437, PubMed:27274078). Expression is down-regulated during biotrophic growth within tomato leaves (PubMed:27997759). The expression is induced at later stages of infection when conidiophores emerge from the plant and produce conidia (PubMed:24465762).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="6"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767852.1">
        <property type="nucleotide sequence ID" value="XM_047912050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CU70"/>
    <dbReference type="SMR" id="P0CU70"/>
    <dbReference type="GlyCosmos" id="P0CU70">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="GeneID" id="71992780"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12902"/>
    <dbReference type="OMA" id="ANAGYLC"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF24">
        <property type="entry name" value="LANOSTEROL 14-ALPHA DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0503">Monooxygenase</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000445890" description="Cytochrome P450 monooxygenase claM">
        <location>
            <begin position="1"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P04798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="24521437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="27997759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="9"/>
    <sequence length="538" mass="60609" checksum="918D726A53FE3860" modified="2018-12-05" version="1">MNSTAANVKPEPGLYGPDAAASPAIARYLIQGPSPLSIGLVVLIGAISSFLLQQFLKPAVNPLSPKFTSNTWPWLGSLGMMIGHWTFWKSCIKESKTGQFSFWLGRTHVVGLSGPDARKMFFEHPALDLHKATDLTPLGVNFWPIHAIFTPRDEKFQKSTYWLRTLTHLMKTPNMERCLPGVIQDARTGLEALKRDTPSGIINTPKVWPVVFKQTARVFMADDVTDDPKLWATTLGAIDTILHTFSPFNTLLPWIPEPSMIRRRMARRALLRVSRGIVRDRHASPKSASKNDAVQSLINLGDPDDNISEFMINAAFVGVVNAHVIFPQLLNALAVHLDWQDKVYKEVTEVADQHCKEQCLPLVDKLFHIPLSAWENSFPNAALMMEEISRIWTCFPTARFNTLYESIPIPGTSEVIPARTHAIYNSTEIHFNPKLYDRPASFRPDRFAPESQKTWDKEPHGLNTWGTGQRLCSGMRWAKLQQNILMAVALSLYRLEKCDKDGKPDPSAYEKQQAMDGDLDEEVAFVLPECFVKLIPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXK6</accession>
    <name>A0A1P8YXK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative effector 38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CE38</name>
        <name evidence="4" type="ORF">CLAFUR5_04375</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943070">
        <property type="protein sequence ID" value="AQA29241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXK6"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573430" evidence="2">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQA29241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="19494" checksum="8A57F30E0D8AE871" modified="2017-04-12" version="1">MQIFTVAAALFVAIAGATEQSEQANRGELSWGGGRYRPQRGGGRGNFPYGGRGGGRGGRGRGRGRRYDGRNFDPNDGVRDYGLRDSCTCSVNGVVDPDVARAACNDLKQTWDNLDFDEGSGACYDDNSIGLEKRGWGAACQNNGPAYDQYNPAYVTSNCDPKSPQDYNVDDDDYDDYWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXS2</accession>
    <name>A0A1P8YXS2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetylxylan esterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14581</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">0WU</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943143">
        <property type="protein sequence ID" value="AQA29314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769227.1">
        <property type="nucleotide sequence ID" value="XM_047913729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXS2"/>
    <dbReference type="GeneID" id="71994459"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14581"/>
    <dbReference type="OMA" id="DPFCDSG"/>
    <dbReference type="OrthoDB" id="2586582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671813" evidence="3">
        <location>
            <begin position="18"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQA29314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="230" mass="23888" checksum="D58B3078B9E5F089" modified="2017-04-12" version="1">MVRTALLSTGFAALAAAAPLSLVQRQVECATGFYIIVARGSNQPEGEGTPGEVGNLIEARVSGSYSVAVDYPAAIISADSIYPTSVADGQNDVTQKIEDYVEACGSDSKIVLVGYSQGGNVMTNVLAGGVAKPAPIDSKYKSNIKAVVVFGDPTFSEGQSFNEGTSTTDGIFSRRDDGDSLELLNTYASVLKSYCDEGDPYCSSDNDSSVHSATVSKYAQDAADFAASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4R2</accession>
    <name>A0A9Q8L4R2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755217.1">
        <property type="nucleotide sequence ID" value="XM_047899758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4R2"/>
    <dbReference type="GeneID" id="71980488"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00610"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF16">
        <property type="entry name" value="DUF2235 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040348126" description="T6SS Phospholipase effector Tle1-like catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="50"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="513" mass="57210" checksum="8E41D80F095EF5A0" modified="2023-09-13" version="1">MAVAPRPCRIYWLVVFLFLLLSTRSLAEADLPFLNQTMADVSRSELASYKRIIICCDGTWLASDQGDNSTPSNVAKLARAIAPNGRDEEGRLVKQIVSYHSGLGSGDLATQKALYGGLGWGLDHDVTEIYDFIANNFEPNDELFFFGFSRGAFTVRSAAALVSNVGILSAVDMTSFTHMWSAWRAQDNKMPFCESAWYRSNKNQLHLKNVQVKVVGVWDTVGALSVPRWPVVSWLQKFNIVLNRKYEFHDTSVSSNIDYAFQTLALDEKRLTFPPTLWHKVDGGPAIALEQCWFPGVHSNIGGQAEEPLEDTDRGQIGANTLAWMVSINIDNLSGMLTFEDAAIRAIVDEHTKALKQNHIPDGWGCGKIVDNFSGWIGRFFWLLGTSVRTPGEYTRDAGTGKPGATNEYMHPMVRIRRERLKGWTPPSLNRWDYKPKGSGQVVQWSKSGAEDIPEYKMKAKNITIALATADGQPRFDTRESLSRSLCPSRILSELDAMVAAREKPLVDGHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L504</accession>
    <name>A0A9Q8L504_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755356.1">
        <property type="nucleotide sequence ID" value="XM_047899954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L504"/>
    <dbReference type="GeneID" id="71980684"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00806"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="47497" checksum="7E3CF4727CFDA630" modified="2023-09-13" version="1">MNKVLKTLPFAVGLNLTSSTICLVSPNSRYASEIDERSKISMPPKRSSAQPGNPPPNSRRTTRAATASQRTAFAASGKTAAGVGPPMLKTQSQPKSTAPTPTPATKPRATTLTTENALSGLLPPETRFSTGVIEALVAPRPVPSHQASVAIKGCILLHGPRAIRKYSNDLENDNERLELQRLKAVTDPRAAVPIPHQREPEKTTDLDHGDYGDLGGSRHHSGHSLGDETDDNIDDRHVQPNYDKGKKPVHKANTAQDAEEPGDTRSGFRFDDPAGRGSQQCEGSNRKDNGGVSPLLSVPIDGPEKDSPTGVDTIGADMAPSLSILKEDHSASKKRKSQVATDQRPEVGTTDGSEQQSPTKRARHSGQGKAEEAQQPPVLRSEPMDQARLTSSAEQMSRKGHLAKKGDHRVEDSVKGGPTQSVGTSSMYSPSEYEKIYEIAGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L587</accession>
    <name>A0A9Q8L587_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
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            <begin position="46"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11092.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="387" mass="43003" checksum="C83DB90DECD5742C" modified="2023-09-13" version="1">MKANGHASGAAVQASILTFSILFYISCGLRLYTRIYIVRQPWWDDALIAISVVFNVIMATSMCLQVPYGLGKHVEDVPPEQLKTMLFWFWLSIWNYYCAAGFAKLSILLQYLRIFGTTRKFRTACYCVIASVIFYILWGAFSTAFYCFPPSGFWDPEAVAEGRAHCQKQWTVKLPIWFFNAAMNMATDIATAVLPLPVIKNLNLPRKQRLTLMFVFGIGGFIIIISMVRLSGLYAVAVSNDPTYDNPLAAIWSATEANLTGLASCLPVLKGMIAKYFPNLIKTSHAATNQPYGASGQHSRLSEKGGRKSAAIWGKKETEINIEETTICGSSDSPDLRSGAGWGWEKEKRTGAIEMETIVEGGKKSYPRRNTDGSEEHLVEVLPAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <end position="58"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
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            <begin position="14"/>
            <end position="24"/>
        </location>
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            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="9939" checksum="F3DAF0C385D03904" modified="2023-09-13" version="1">MSAQGYYGGGQPQYGGQPQYPPQSYGGGYPQGPPPQMNYGYQQPPPMQQAPPPRQDKSRGCLGACLATLCCCFVCEEGCECCADCCECCMDCC</sequence>
</entry>
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                <person name="Samaras A."/>
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    </dbReference>
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            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="70" mass="7895" checksum="46B7AFC849D5B217" modified="2023-09-13" version="1">MPILHIVLFEFKPTTTHSQVEDVCKRMLALKDNCIHPETKQTYVKSYGGGRDNSPEGQQVGGHSRRPTQT</sequence>
</entry>
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    <accession>A0A9Q8L5Z5</accession>
    <name>A0A9Q8L5Z5_PASFU</name>
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        <submittedName>
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        </submittedName>
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    <organism evidence="2 3">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900611.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981341"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HSDL2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
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    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="33911" checksum="8FC676E6ACAF9C94" modified="2023-09-13" version="1">MSGNKPVAIVIGASRGIGRQVAIDLARAGYAVVVAAKTESDASKCKPFPPNPNSSASTINTVAREITELHNGTALPVAVDVRSYENIQAMVATTVKKYGRIDVVVYNSGAIWWSSVEKTPMKRFQLMQRVNPEGLYGTVQAVLPEMYRNGGKGKGRIVVISPPIYSRFFKGKTAYSMGKVGMSVLTMGLAVDFEREGREDMAITSLWPAAAIESAATQSGDGVEDLRKDLRTPDIFSDAILSMIKAPAKDVSGKTFLDEDYLRDHDGVRDFSKYALISGSTPRRIMPLKLPDLTVAEQDDEGVRMESSKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L667</accession>
    <name>A0A9Q8L667_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        </source>
    </evidence>
    <sequence length="977" mass="107540" checksum="71994F2EDF624C38" modified="2023-09-13" version="1">MDRMPYGRPQERELGHNQTAPPPASHASPFPPPTTQQPPMQIPFSDPFHSSRDPFLPGGSRRSSLGLSSRAWPPSQGNNAPVSHQHHPLHLSPPAQPVSQGPPLPPPPANGLTMPPQPYDDVRRRSIGAAGSPQQYGRAPVDPPPPPPSFPARNMPPPSPPQNAPPPSSHFGPAPRGPPISSPFAAMRDPASHRPDMSISAILGGGDGHRPNGSPHSSAVAPALTPRSMQPPSPGRARSSSMREAGDRNMNNSSPPRPGMFGEPARMGSEPQRDGMYGSPHFRRGPGHSFLAFQPSQEHAHHLNGHGAPVRPNSQPVETFPRHVDDLVRREGPFEQRAGPFRHFGEPLASPRHEPPPLRQERPMFQGGLTSHPQENATYSSPRMDRERSSQGPSRFQGGNFPNPLRDEQQSLFRPTFPPTSHPAPEAPRESIENRAQDTRRQLSRPSPPPMHLPTYERGRNGFVDRPMTLEEHQRMEMMHREQHRKESEGSVHRALLNISPELDRRGRNSPLPQAVQGAQPRHIGPGGDNPGIKMEFGRMFSGLGAGVGSTTPKPHSHHPPNGDTTPSRMSPSLRHVEGSDLVRAAVAEIDERRAGSKAGSRAGRRNRRRSRDDAEHLEGDGRGTPDLQRGGKRAKTAHHHHHHVHPHHHHHHHHEGGETTPGPHNMPRFPSNPLSHANLAASQAHHHHHHHAHPTHPGHHHHHTPRAAPAPRKPAVSVISKRVLEETAKKPRRHLGSQLYTTDVTLPAPADIHVDSKIKFGSTSKPIPAFHDHQNCTFTVRVPRDYLIRSDTNADEYNLEAICKRRQLWGTDIYTDDSDVVAAAVHSGWIRGDFGEHNEDIRQICDNTSERDVDDGPPLSLDERPARPVKVPEGHDAHITIVILPPLEAYASTHQHHIWSRDWNKTHDGMSYMIHRIDFVDEGRSGRYVERNGAARKKRIAIEEANRREAAAGLLMFANGSGAGPSSGSGTVRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7N5</accession>
    <name>A0A9Q8L7N5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferric oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756729.1">
        <property type="nucleotide sequence ID" value="XM_047899558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7N5"/>
    <dbReference type="GeneID" id="71980288"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00410"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="180"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="649" mass="73009" checksum="ABB9FF00D23EA5B1" modified="2023-09-13" version="1">MRKWCRAEREHVPSGSRYTSSTMQAPPTSLRRRLSYLVAPTLLLSCAGLTIGLAYAPCYSSYCVEYFFPYHTRIHIALFYSLLAVIGLSLTARTWSLPIQRLSQWHFSEKHVPLAGKPLSVGAFVLGFLIVGATFGSTGYWYEAQQQFWFDRGATVDWTEHMFRLAWCGITGHWCDIWAGLVVIPVGRNSILGRTFNIHTSTLLLVHKLLAYGLFAFAIIRGLFFFSWLDVYLKASYEVQGHFQTDNPAYTWEETEAMGYYYAFTLPIALIAGWLLIPAMVITGLPWLRRNHYNTFYFTHIILAFLVIWALCIHSSTGFYFLLPGIILWVADWAWRVSNSLYAKQQVQIEYAGNDWYRIRLPWGSKISSGNSEKALESGHVSDDSEKTVVAPSTSSPIATYYINIGQISRLEAHPFSAVYSTVSNSGPVLLFQRGPAKKKDKKRDKEWTWKLSYLAHDAANEANPLTLPARIEGPYHHHVPEMHAANHIFLLVGGTGVTGALSIANWWAGKYDASEQPAQRSLRLLWSTRGQADWQLQEVEDLRRLAQECPNMELVLHDSTQSGRIDPHTALSDFLGSVPAESTSSTLGWEGAKSQKEGSAWTYVSGPGGMMKSAEAACVQQQIALRRVGKTGARGIRDLSWYISNFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7W6</accession>
    <name>A0A9Q8L7W6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extracellular serine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756720.1">
        <property type="nucleotide sequence ID" value="XM_047899279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7W6"/>
    <dbReference type="GeneID" id="71980009"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00131"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000251">
        <property type="entry name" value="Extracelular serine carboxypeptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="544" mass="61512" checksum="3382ABD663051294" modified="2023-09-13" version="1">MYASSVFFESWRISSSDLGFDYAEHKHPITTLAKRAGEDPLQILYPEHWIDVPVDHFQNETKYEPHDHTTFQLRYWFDAQHYQPGGPVFVLQSGETSGTDRLPFLQKGIVAQITKATNGLGVILEHRYYGTSFPVKNLTTENFRFLTTAQAMADMAYFAQNVEFPGVKGNLTSDKVPWIAYGGSYAGAFVAFLRKQYPDVYWGAISSSGVTEAIWDYWQYYQPIIEHAPQHCIATQRDLISVVDGILIGKNSTDLPMQLKAAFDVADLTYDVDFANYLGSAISWQSLNWDPAVSSDSFYRYCNNITSAEALYPGLESRRSNVTNLIDESGASTNKSLETAMLNMIGYFNTSFLASCDGTADSCFGRHNQTYYDLTTIEDANYKSWPYQYCTEWGFLQTGNTPPEYGAPIVSRLMTLEDQSLICRAAFNITTPPDISTVNKYGGYNISYPRLAIVDGDWDPWKPSTPHGFEFGAKERMSTASEPFILIAEAVHHWDENGLFPNETTATLPPHRIVDVQAQELQFVQEWLLAWEQACMVEGRWELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L879</accession>
    <name>A0A9Q8L879_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757029.1">
        <property type="nucleotide sequence ID" value="XM_047900165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L879"/>
    <dbReference type="GeneID" id="71980895"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01017"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="12077" checksum="C67B985C27BDA661" modified="2023-09-13" version="1">MPEELRDIQAKATQPTPETPQVDRSDEPDSPQKSLVLGKSSSEIADPLSEFNVGDEVRCTRADGSTSNYIVAASRLSEKKMWEYQLRASGSTTKYNSGQWIAESQLAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8F8</accession>
    <name>A0A9Q8L8F8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757005.1">
        <property type="nucleotide sequence ID" value="XM_047899648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8F8"/>
    <dbReference type="GeneID" id="71980378"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00500"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="114"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="39968" checksum="A8118522ECCFB36D" modified="2023-09-13" version="1">MAERIEPTMLDKLLFAPVLAKVLVATILRAVTLPLTAFTGGSRANQPMKDIVFAALRTQLSSINAAQEQWTLATTTEKNYLDFAGKQKFQPESTVLNSGLRLHWLGPKTSEKVIVFFHGGGYVVPCTDGHMKWLLHLQTELSKKTSTSTSVIVVGYTLAPRGQFPKQLQQAAETLAWLVGKQERRPRDIILMGDSAGGNMTLSLLSHLIHPHPDAIKITLTEPLATSILISPWARFDSDYDSWKRNATSDMIPPAGTHRWSSLFLGPKPANPYSEPWRADEKWWTGLDKVTSDVLVWGGSAEVLVDSIEEVGGQLKSAHPRTEVVIQKGASHEDFIVDVLLGYKHKAEGTKVIESWLSERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8W3</accession>
    <name>A0A9Q8L8W3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAC-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757306.1">
        <property type="nucleotide sequence ID" value="XM_047900299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8W3"/>
    <dbReference type="GeneID" id="71981029"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01151"/>
    <dbReference type="OMA" id="SQKMIFA"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="8">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="22050" checksum="5A310782F59D82B8" modified="2023-09-13" version="1">MANPRVEEIVDEPEKKVDEVEDESSDSDEEGGDANIPAGAQVAVHSRNEKKARKAIAKLGLKHVEGITRVTLRRPKNILFVISQPDVYKSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAQSANEHAGHDHSAEGADKGKAIEGDAGKKAEEEEDDGEEVDDTGLEAKDIELVMAQASVSRKKAVKALKENDNDIVNSIMALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9J7</accession>
    <name>A0A9Q8L9J7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="8">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PAN3</name>
        <name evidence="10" type="ORF">CLAFUR5_03039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9J7"/>
    <dbReference type="OrthoDB" id="204958at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="634"/>
        </location>
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            <position position="314"/>
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        <ligand>
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            <end position="370"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="685" mass="75540" checksum="721A7B58D0754C36" modified="2023-09-13" version="1">MSTMSGGSMRIASNAGRQRYENRAPINSVLCRNGPQCRKHLEGTCNYNHDFGSGAPNGLNVPKKSLNVESPSFTPKPMNVQPAKIGISPKAASAAAFTPRGSGKALCGDVKIMLTYCTTGSVTPAAASHSKEHSGDFNPQMTFQPSQQFQEFILSQSFLASSQVDHAPQLQQQLGTFGDPFLTHQSIEAAQLNPYAQQAPALGGQPFFQDASSYKHPLNYHLYASIGPRRENLMPHQRSTADFFLPDNLREELQQKSEATLQTFANSTLPMNVEYFHSLVALDSNNTGSKTTFGYPSWIYKADSSRDGHVYALRRIAGFRLTDEACIRTINHWKRISNSSIVQIHDAFTGRWFNDSSLIIVTDYHPKSQTLAEKHFSTGRTIGKASAQVTQEGEIWGYIVQMASAMKTIHDASLAAQTITPSKVLLTSKNRVRLGACGILDILHHGQDRDLGDLQRNDLRDLGRLILGVATRNVAAHQNILKALEQVSRSYSERLRSCIAWLLIPPVAVDATGSSAPQSAPEYNIAALLTSISDKVLTAFDSVLHLEDDLTSNLMRELENGRLARLLAKLNVILERPDTGSTPNATTNPALLNQPGSAWSETGERYYLKLFRDFVFHQVDPEGRPVLDLGHIVTCLNKLDAGIDEKIQLISRDEQSMFIVSYKEVKRGFEAAWAEISKASNPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBY6</accession>
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        <recommendedName>
            <fullName evidence="3">MULE transposase domain-containing protein</fullName>
        </recommendedName>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO14660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="21236" checksum="4650FD77A5F6B1E7" modified="2023-09-13" version="1">MRLLEDKGFIKGYDTFTEGDNAGRLRSLNVIHPDCLEVYAEALELLVMDVTFKTNVYNRNVLNVVSATPMNNTMPWLRAYFEERKLPMPKAILNDREEALLNALDEVFPETPTILYEWHINKDIQAKLHKLGGNFAQVPRQDVAGRTYWIESELSNQFMSDWQVVLRSTDEQSFEEQRKELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDW0</accession>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
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        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="156" mass="16496" checksum="13B8A102C6C1C66B" modified="2023-09-13" version="1">MANTIHSTGRGGEQWPSVHHPSPSQRYSQTTGAGNIGPDGNVYVDGDIVREGTPGVSKEPEYSAGRGGAGNIAHAEKAGVPSQEVVPESATRVEQPGGAYDNYHTGRGGEGNVHKEKYGGHSQPQKERGQKESLLHRAKHAIGLDKKEKTPEPSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEI8</accession>
    <name>A0A9Q8LEI8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760322.1">
        <property type="nucleotide sequence ID" value="XM_047903933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEI8"/>
    <dbReference type="GeneID" id="71984663"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04785"/>
    <dbReference type="OMA" id="KTDERYW"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF29">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="66"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="563" mass="62564" checksum="C5D243BA6C98337B" modified="2023-09-13" version="1">MGLGVLNDHKLSHVPGTATLEDLDPLASAARGHNVKKAKDGTILVPQPSDDPKDPLNWPLWRRDLICGILCILSLIASTLSPLLAANTLTLTLYFRKPFTDIALLTGYHLLGVGLAGFIFVASGRIWGKRHLYIGGTILIVISSVWGGASGHNYNSLMAARFFQGVALAPFEALVNASVGDLYFVHERGKRMALSNLSLFGGAFFTPVIVGKMTHTMGWQWTFYFIAIFSAALLPLVIFFCPETAYTRDSSYNTDTSWARMGENSDSQEWKVSPSLEEQNPTSFDKPMDTDTYQHNHEAGSAPHNTIPAYSWRSREALMPFNGRKTDESFFKLVLRPFPLFFHPGILWACLIQGAIIGWTVLIGIVLAAIMLGPPLFFNEVETGYMYTGAFIGAVLGFALAGLMSDWSARWLTRRNGGIYEPEFRMVIVIPMLIIGCAGLYGFGITADDTRKFGWFWPDFFFALEVMSMVLGAVASALYIVDAHRDLAVEGFTCLLIFKNIFSFGLTFSGLDWLVKAGIKPVFMWISSVQVVICLLTILMYIFGKKNRSFFARHDILQICRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEM7</accession>
    <name>A0A9Q8LEM7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-dependent RNA helicase DBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760366.1">
        <property type="nucleotide sequence ID" value="XM_047904483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEM7"/>
    <dbReference type="GeneID" id="71985213"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05335"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="309" mass="35062" checksum="C1E9BDC20B215739" modified="2023-09-13" version="1">MLGMILLVDDDQRRTNNEIVNCMRILTRVIPFIYEAQHLRDWHDSFFWEPRRPWSAEPKREIREDMHIGKPLGQETLEIVTNYLFFSGIGRLSYGTADPLPAGGKHEKNQQEVITSTGCLLQLGVVLGSKHHSPAGFFTARHHVAPAACAARSHEQPSAPFSTPESPPTTHAFWKQMLDKYTFVGDGFVDFTESRYIGNFLDAWMGQEREPGHQPEKHWHIAVSVGGACKEKWIAVKLLARIQRANDEKVWNRVEAPTVAARTPAEVDEFCRVNQIIIQGRRVPKSVETFDEAGFPNYVMSEVKAQGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LER4</accession>
    <name>A0A9Q8LER4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04997</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760426.1">
        <property type="nucleotide sequence ID" value="XM_047904145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LER4"/>
    <dbReference type="GeneID" id="71984875"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04997"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040378684" description="Rhodopsin domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="19247" checksum="42D42EA2F396B7B5" modified="2023-09-13" version="1">MALQFLINTSCVIRIYAQCCSHVSALWGDGEVTSCLDPVHQTNYGYFQSAFNSVSDLYLTALPAIIIWRLEIKPMVKAGLSFLLYLSFFAFIASVVKTWQIRILNERGDITGNFVDFVIWAALEIDLVIIVASIPTINRSSQVTNGEVPSTIANCRTGPAVTRKHLRGGMWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF61</accession>
    <name>A0A9Q8LF61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760678.1">
        <property type="nucleotide sequence ID" value="XM_047903104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF61"/>
    <dbReference type="GeneID" id="71983834"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03956"/>
    <dbReference type="OrthoDB" id="3341310at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd06262">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050855">
        <property type="entry name" value="NDM-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951:SF4">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE MBLAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="394" mass="44406" checksum="8459C3C54A7F78FC" modified="2023-09-13" version="1">MSLGTDRPDFSSPSAQPLTTPRSQCSPSMSHTMLTHKDPRSPLSASFTTTRINKTTFVVEEDDAFGEHPLIYVKLHPTLPLLITSDTGGDEPSERNKHAACIHLREYLEKYPVPCNNNSPLNPGGARKYIIIVTHCHYDHLGGVSQFLQGGTTEIIACAAGRDFIESDVETHGLFRFVDKVTPYFNVTHWAQSFEKLKYPIPHEDDDKLDEKTTDLGITILHTPGHTPDELAWYDHAEMHLYVGDSFHEELGNERMPIVWPSEGNMIEWAFSMQKLKTFIKAENSHAERPTSSGSDSGFEKVARRVKVGCGHQTHSADAEELMERLERLWWKVLTGEVPAGKKEVWRNDATFTWREENVVSGMSFRGPARLVDEARKFFLNGERSNGEHSAGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF93</accession>
    <name>A0A9Q8LF93_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04998</name>
    </gene>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
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        </location>
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        </location>
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        </location>
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        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="348" mass="38997" checksum="5AB062180CD6DDC1" modified="2023-09-13" version="1">MQYHKQITTLLSILVAQVTCQTPTGTAPSTSEHLNVAYGDTVLEANELLPQAFQSSDKVSGDHMLLLVDQLIPQSSIDSSGPQTPGLEYCRTTRLHWFQTDLTQLDNGSFVSETAPMATHAHTYTFYLFTQPSNFTQDAATWDAGRVYDPISVYDRMNFSTSAIADVPGVGAPLAANFMRVQDPNMTTYGTAANGTCSMDSGLSNSTEPGSSIHVHRLDSKGEDDDGQQQRRFEQVGAEYQKHVKESHDARGMEKWYKTEMSILANEKDRIPRRLREIGQEKLELEAKLDEVVKNEKRFVAKYKAEHDQGEKDRELKERYEQYLDLQTPEMRVEGEGGGMEGVEGEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="9 10">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="9">Race5_Kim</strain>
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    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
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            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        </source>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
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    </dbReference>
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        <property type="entry name" value="Multidrug resistance protein D"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
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        <property type="entry name" value="MFS_trans_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="121"/>
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        </location>
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    </feature>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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            <dbReference type="EMBL" id="UJO16789.1"/>
        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG46</accession>
    <name>A0A9Q8LG46_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05170</name>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17030.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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            <end position="207"/>
        </location>
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        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO17007.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="207" mass="22693" checksum="703695E570E5852F" modified="2023-09-13" version="1">MFAGVPTLMGMSAMGYNSPNNSAAGAHGACTATAPLDGKVIEEWSVTSKAICEAEGFDGMRQVFVHDKIAKLICMLVFDKMDQQHCAAVDRIFDKLFCAGKERGFSIYRAHVSHMGEPENVDKNDFNGHAYRHFIESLKVVYFVSTPNPAADDVQDTVEPTGILSPGKQGIWPKKYRHLRRSPEDPKTGTGSNMEHSGPSKTTRSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGP7</accession>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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    </feature>
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        <location>
            <begin position="3"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="19599" checksum="38A386E876778237" modified="2023-09-13" version="1">MAKPVHPATIHFPIAFLMLANGLDVLHHLYAYLPAFITSTLPTSTDSAKASYYLLSLALLTSIPAVISGGGEAMKMIQKSGMYEKDGSIRAKVKATIAHAVVNDVVIAANTYIWYQRRLAVKESLSGKVGIDAAYRPETWMVLGEAVMTVLMLVGANIGGNLTYVFGIGLGGGNSLAPKATSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH37</accession>
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    <organism evidence="8 9">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">Race5_Kim</strain>
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    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO17329.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH37"/>
    <dbReference type="GeneID" id="71985543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05665"/>
    <dbReference type="OMA" id="GDWYCME"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="133"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="466"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="601" mass="66603" checksum="511DC042591684DE" modified="2023-09-13" version="1">MADTCIVCLGDLRTTVDGDPPPDAPAAPADDAGEDSDAKQASIYNAQSNIETDEEAIAHLLPCKHDLHNSCLKPWVERANSCPICRTVFNMVEVSRTVGGQVIDSYAVMDKSQEAEVDPTMVVDDELFAVELVEPCLICEVPTDGLGAMYCDGCDRSVHIFCAGFDADVPEVWYCESCLGHLEADADLLGLASAAGRGRRRRIANGNGRGTGGRPRHRRNDDAMWARVWQEVNRRLDMDLDFPYDEEPAETRTEEQRREFERWQARFNIADRQGASNRLRGIAQARINGRRIVPATPESQEELRAWNAFDKARESHEEEPANTRRRKRRRTDSPASPRESEQPSAQPELKRPRLRRPRNAAPEQPESSAAAARRNGEDHTFLSSLLREVENKATSASSPAASDYVCGQFSPRNSSPVRSPASSEDGTPPAATTPPPHRPLSPPLSSQIMPATSPLAQIFSPFSPAVSRLDLDQPPTGAQHRGRRRHAREASLEDTDEVAHGRHSSSSPSRALSYSAKEEIQRMVKLSLGARYREKEVTKDQYTDINRDVSRKMYDLVGDASALMDQESRAKWQQVANDEVQKAIDALPTTPSVEDHAGEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHB4</accession>
    <name>A0A9Q8LHB4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761535.1">
        <property type="nucleotide sequence ID" value="XM_047904365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHB4"/>
    <dbReference type="GeneID" id="71985095"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05217"/>
    <dbReference type="OrthoDB" id="10496078at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="281" mass="31747" checksum="FAA13BE20BCCDB21" modified="2023-09-13" version="1">MAANKLRAAQTVLATYELLERILLFVPMNHVYTLQRTCKSWNSLITRSHAIQKKLFRLPDGAPTKSKTPGPYMTPWNLTVPEYRLENRKCNPNIGLVFLEHITHREEAFPILLPDLNYSPPARPTITAIRSSVHNELGETDITDLKERALMLEMKINDTAPLNSWHEMFITQPPITAVLFGCHSEVESYQMPLSGNSPSRSHVFQVWNAGGVRFVDLAFARKEFVMRQGGKDGWTMGLCFDLTGKAVSEKSGREMEEECCGKYTAGEECQCLEVVREEGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI61</accession>
    <name>A0A9Q8LI61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762447.1">
        <property type="nucleotide sequence ID" value="XM_047905608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI61"/>
    <dbReference type="GeneID" id="71986338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06460"/>
    <dbReference type="OrthoDB" id="10249612at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="226"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="380" mass="43080" checksum="291142B99775B417" modified="2023-09-13" version="1">MAPSTLTEVFGDGNNAYFSNGRIDRLAFLRMQHELMHKASTSSSAKYWTFNELNALRDWDGKFAYVDYEDVADFIGQPYHKDEKPQIQEFDPDQHHPSLVFLGLDLEGGCRSNAVQLGHYRGQPYFALDVTSSHYDAFRAKQAEKGRDHTPTRIDLKLDRNDSAILSHARSLLDWNTRNRFCSAWGGRTLSSNAGHKVVCPPNDAGIPRKRSCPTRIGLHNQAFPRTDPTVIIAPISYDAKRVLLGRGKRWPEKYFSCLSGFVEPGESLEVATRREAFEETGVRIDRVQLHSSQPWPYPSTLLIGAMGQCMDGVENITYPETELEEAKWFELDEIEHALNNGANPMWEPPIKGYVGPRVPPGQLMAHQVLRGVLKLFHRR</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="122" mass="14080" checksum="5452C9DEE54870A7" modified="2023-09-13" version="1">MSTHAPQARALYRRLLRELPARSPSILANPSPIQKHIRLDFSNSQSNSNDALSLAHQAQKPIEHRFAEAEQFAQYLTAQRQYTTLIERYNPGMNMSEEDKVRLTARRVGMELPVDLRHVKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIX8</accession>
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        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
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        <location>
            <begin position="20"/>
            <end position="459"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="459" mass="47698" checksum="CB02A0DFA5E31681" modified="2023-09-13" version="1">MVQVSTLATLAVAVVGVHSFGAKCPDNKCAQKATPYCSSYLGVPAGKTVTSTTTSTTTVIVTKYTNTKNVRGKPTTITTTITVPKTEKTTVTSTSATETQSTVTVAPTCKAPTVIPDVPSELDPEGILLKRQNHSYGQPYGQPAKPTKPACMNSYKERADVTKACKCLSIKPSVTTVKKTATITQTSTVKKCKEITTAPTVTSTTTIEKGKTTKTETTTTILIKTLDPTTVTEGPIAIPTSFNIVSSNAQFAFGNAPGPVIPNGLYATIDPVTEGGPVGQQQPIDFAQAIAQLATVFSLGEDGALTIGDDQGTFEQTAFFTTGEVLDVTGGDNDPLLITYGADADQTKPVSCVIAANEDGTCGLTCTGSGFAPEVQYICGLDKSFYIGSGQDAESGDATCFAFSPLVVDAASVTIELPETGDLPDLGDIPDLTSGGGAVLKKIAQQTVDKSVHSYGRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ11</accession>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO18280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="CTINTTF"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:protein heterodimerization activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        </location>
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="29955" checksum="054050EEFCE47BF7" modified="2023-09-13" version="1">MDYRPESPDLSNLTGARPVSPDLSGINTSQSQPLGEFNQQAQHFPTAFGAGHRISSASTYQPQPTSVPHYSPYDRQYQPYQQYSPPTGMPPRQFKAEDEDEYMPDANDSSKRPRRLKQEHTIGTNGAPPIDAAPFPIKAEAGDATLGCTINTTFPVARIKRIMQADEDIGKVAQVTPTVVSRALELFMIKLISQSAVQARGLVGAGGTSGKGPKRILAQHMKAAVNADDVLDFLGEIVNKIPDAPVKAAKKETGSESEEAKPKRRSKKRKDSGDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJP3</accession>
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        <name evidence="3" type="ORF">CLAFUR5_06113</name>
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    <organism evidence="3 4">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905261.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LJP3"/>
    <dbReference type="GeneID" id="71985991"/>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37383" checksum="75A51AA81152B605" modified="2023-09-13" version="1">MIRANRCNHERLHHNLAPGAACDAISKAEADDIVTPRRAPRGRTTTPAASRKPALSHQLPLTPPSTAAQAATGSPESTESDPLGTPTPAPLVSHFGLPALSGFTPQGTQESAVEQQSDEDSGIGENIIVASRRSAQASGGVPARTIVERTPQSEISVGNNINLPARQPIVLERESSSASTQVVPETVFDRTPSLGEAGPSGYHDPSYRRHSSADPEPNLDNIAQHMTNLEIQHLRRSRAQYAHELEESTGLVNRLQTRRQIHEADAVINHSMLEQLNRERRDAWDQASEAEYQRRRTRKRLGVVLAMLVIMVSMYGCWCVYMSAEFEYINKRRIEVLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2V4</accession>
    <name>A0A9Q8P2V4_PASFU</name>
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        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO11159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2V4"/>
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    <dbReference type="OMA" id="HTMALGG"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="246"/>
            <end position="330"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="104"/>
            <end position="113"/>
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    </feature>
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            <dbReference type="ARBA" id="ARBA00004651"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
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        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="UJO11159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="373" mass="39899" checksum="7E81A984BD755F50" modified="2023-09-13" version="1">MAPLPCSPASNSTASESHSLPTSDDSDDSLITPRAGPSDPTLRTPAKLSKPTVPPFATSPESSQRPSSLKHADGQPRYPYTYTGTAGSSRAIDAGVDGRERQRSVTFTPQTISPKGPRPNSYSHTMALGGSPVRSRQDRESEDVAESSADEHTAIVRKSTQLKSNYGAANDDNNDIRSINGQAESPRRRKSDSVMSLKGNRADAGVPARGGQELLTEQEAEHEGWFRSLVDKYGSVELENKGSVARDHLALERTFLAWLRTSLSFASIGIAVTQLFRLNTSIASSDPDAVQSSAASTKLRSVGKPLGATFLGISILILLLGFHRYFESQHYVIRGKFPASRGTIIIVSAVATALIIASLIVVVAVAPEASEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P326</accession>
    <name>A0A9Q8P326_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DYRK-family kinase pom1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00316</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
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        <property type="protein sequence ID" value="UJO11282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047899464.1"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_00316"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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            <end position="1461"/>
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        </location>
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        <location>
            <position position="1194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        </source>
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            <dbReference type="ARBA" id="ARBA00022527"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
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            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO11282.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1639" mass="178724" checksum="527931DF63FE9AAB" modified="2023-09-13" version="1">MDIASRFQPGRQRAPAYLDRNGNAAEDSGTESESFIRRKFQRTNAEATNPNDNTFRKPSIPASASRPQQAEQRTSFSHNRRRSTALRENVRVPSGPREFPSPHKRVASGSIHSITPSMSEATNTSRTFLPQSATEPNFSKIADAPRFSFANRSSTDVNDPPLTPAGQASNDLDFIPTVNFDDLQNSIANYDGDGPLLSDFPEVGGRPSTKPKSGNMLRDASLNASRPPVPKLEPRAEHGMSRSQSIRRRLSAVTGGKPNNTPNITSDSRDGNASQASNLSLRPRRQSTAPQGPPPAEPAPPPLGVSSRQPRKSLGPGVIASMMEGRKASQPLPSSGTDPALKSALARSGSLTKAQRRTTMQPSASGGAELPRVATFSATTQSRANKVKSLGPPAREPQEPNTPNGKTTTRSGQNRAHTPSSSGNNKRQSTMSGRASGLGARTISPTDARRLKRLSMMQAPPLPSNPSTTSIPKMPTQAQEEQSVKVEVPRVAQPSPSFIPQPRRSSNATPSSARDSPGPENRNSQQYGGVQLSARSSFSSLVNSGSTSRLPTSRPRSVHSSTAQYGEVEEVVPPVPAIPKAFESPRDADHAPFFSGVGKSLQNGSDPVAADTEAEKTSSHRLSKLSCEKPSEPKARASLERPRPHYRMNTIDNIERSITLTAAKPQRSQNNNLQPLRLPPLNLMPINHRDANRSNSFPRPSQEVEVREHPSIAQTPEPRRIAKTPSTPMTASKATFSGRQYEDFAKQKNMRSSSSHYALRDLMQLDDDTTKFLDDSDAEFMGVPIPSTKQRSAITPFSSGSLPKASGEFTRQRSRPSGEYTGEYSMTNFEEFQQQSMKPQGPRPSRSGTINTIASYKTAETSSNHSPVEPAGQPEGKKESSGLRRKLSLGWRRSSSKSNIQTDNKSSPRGDGSFTSDHDKATLQKLASQMLPPKLPASATWTGDIPSIPPPSARPSFDSIRRKSTAPSITTLSTTNGGTDQNHTMPAIKTRSMHSEQPQPVNGSNRATSWSTTNPARPPTKAPPNLVKSRQATATPIISAIIKDKDDLAADDEMKRLSQKRKDVDTAAKDSEELKRRAIARSPKSPENVLHDRTAALNIFERGEIMDYENQGVYFTGTKNARKIIGSLTPSPQPGDKDPKAGNYGYDDERGDYNIVLGDHLAYRYEVVDVLGKGSFGQVVRCVDHKDGGIVAVKIIRNKKRFHQQALVEVGILGRLREWDPDQTHATLSITSSFYFRSHLCIVTPCLSINLYELIRAHNFVGFTLPLIRRFARQLLSCLVLLQNKHIIHCDLKPENILLCEARKADVRVIDFGSSCKESEKVYTYIQSRFYRSPEVILGSSYGLGIDMWSLGCILAELWTGYPLFPGENEQEQLACIMEIFGPPDRHLVERCTRKKLFFDSVGKPRVTVSSKGRRRRPSSKSLSQALKSEDEAFLDFIARCLRWDPDRRLKPHDAVNHPFITNQPFSQRTGGIPDEARRAARLRSTAAAPATNGGIPSPVKRTHITTNGTTSSGNAFAQQQAQAQQTPARERSRPLPETPQTAVRNGGPVLQPGSTTQGSPSKRVPVNRRESGVPVTNVAPVAGAKRANNGQVSIGSASGMSFSQRQTSASSSNTTNTTGSLAQMAAREANNAAARWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3D8</accession>
    <name>A0A9Q8P3D8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755963.1">
        <property type="nucleotide sequence ID" value="XM_047900080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3D8"/>
    <dbReference type="GeneID" id="71980810"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00932"/>
    <dbReference type="OMA" id="TPEEWWV"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040276640" description="Peptidyl-tRNA hydrolase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="28754" checksum="B800995957250F48" modified="2023-09-13" version="1">MRASPLVLALPLAAAQQFPMLDSVIDQAKGWFAKASGSVAAAVSSATESASIPNPVASGAVKIAQLNVHRVDLNNFQELIKPGSPHATPGIETWEVFVTGGNKTCFGMCNRAETAFNESVALVAASPNPPNLGLLNCETDGVLCHAWAVSPPQLLHMQLPQPLADQSTPASTVRSIKLNRTTVTAPEIAAIHLQDKYLETEAYGGFWHPFDGPLAKYNLAIPAGYVIWGFSQIPSWAFMIGISFFSRTIMGRRTQPGGGRAPAAGQPAPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Y2</accession>
    <name>A0A9Q8P3Y2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidoreductase phnG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756607.1">
        <property type="nucleotide sequence ID" value="XM_047900923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Y2"/>
    <dbReference type="GeneID" id="71981653"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01775"/>
    <dbReference type="OMA" id="MIKGRDY"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="416" mass="45472" checksum="BDF12F6728950374" modified="2023-09-13" version="1">MPEIRNIVFLGTSYAGLGAAHYFLKHIHPTLPKDEKVTYRVVLVDPSTKFYLRHASPRALASEALMPNKHIFLPTENGFKQYGDTVTFVQGKAVSWDTESRGVTIRKANGKEEVLLYHALILATGTKTPSPLYSLQGTPHTDIEAALAEIRGNLATAKHIVIAGGGPAGVESAGELGELLNGRAGWFASRPSHPQAQITLYTNSDKLLPVLRPSIGKQAEVFLKQVGVDVQYNTKISSSQPLSNGQTSVMLHNGEEVVTDIYIPAMGLSPMTEYVPKHLLDPQGYVKTNDQTLRVNAAGPRVYAVGDVGTYSRNSIIDIMDSIPVLETNLKRDLLAAHVDYNAKPSGPDRLFKAGPAETQIVPVGRSKGVGALFGWRLPSWFVWLLKSRNFMVTEAGVHDRLMGNDWAKEKAWNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P472</accession>
    <name>A0A9Q8P472_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757039.1">
        <property type="nucleotide sequence ID" value="XM_047901429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P472"/>
    <dbReference type="GeneID" id="71982159"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02281"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18607" checksum="E74E860484146FA8" modified="2023-09-13" version="1">MSFARDERLEETFSFTCRARTPPPFLLLVRPLLVIHFYKKHLQTFPATPTSRTRPPASSQQDTTTMMANPNTIIITSDEVLNLHGIPQNCKTIRNATTTTITCPSPINSFNIFTHAHTKDPPATTSHPLTLDSSTLLSGMLVGLLVIFGIADLARRVQEFVEKDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P499</accession>
    <name>A0A9Q8P499_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757114.1">
        <property type="nucleotide sequence ID" value="XM_047900532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P499"/>
    <dbReference type="GeneID" id="71981262"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01384"/>
    <dbReference type="OMA" id="QIEWAST"/>
    <dbReference type="OrthoDB" id="10511019at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
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        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="539" mass="60242" checksum="E3E9F05420270335" modified="2023-09-13" version="1">MADSNSRSTRSTAIAVQQRPKKTYKEPQADRVATVQPGWTHLWTNNERIVLRLLNELFPWKPDERTTIFNTLFKDEHAAAGLSAGRDDGSLRAQWSDRTRPGRAYWENIKAGPQGRKEEREWQALETEVRRVAKEQGVQVTGSVGEETKKGEEKNKERATIGSEGAESSRKRKNEKLAQQAVGRSRKSGKFVKEAKGKPRGSEAEVQPDGEGGMEAARQLHEEDPEQRPEPEDEQSSRKRTNQILAQQAVGRSRKGGRFVSERKKGKQRAGEVEVQPDEEGTEIDGQQDEEHGERDDQQHDRPELGQPSRKPKNEMLAQQAIGRTRKGGRFTIDDGMDLDEQHDKQSGSPPTRTTLDIVSTDTASQDANIGLVQTSLDAPPLPMIHTSQIEWASTDPFWTASPVPGYTHIPTTSPLYNFSGKTHRVHDLNSRPTDTILCNPTFCNVCSSTFLDPVTATSPSGGLPYVHAKDLQKVDGKWIFAPSCGEGFDRQNTEYTEWFRRNVVFGDGVARTVAVCTYAKCWVCREHTVVMRKKASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Z1</accession>
    <name>A0A9Q8P4Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757730.1">
        <property type="nucleotide sequence ID" value="XM_047902444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Z1"/>
    <dbReference type="GeneID" id="71983174"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03296"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15335" checksum="E1E569E8E5291AF1" modified="2023-09-13" version="1">MALRSCLCDRLKRQPAVRGFYLPSDTYSEATAKREDRSASQAVATTSSPAPADSHPIASPSALEAIMRQLQQLQGTVNTLQADLDQERMYSDSLKDQIEKVEGSCKQSDQNIKAVQAKAISRQDQQHETLDALQRDIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5V7</accession>
    <name>A0A9Q8P5V7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle sec65 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758677.1">
        <property type="nucleotide sequence ID" value="XM_047902173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5V7"/>
    <dbReference type="GeneID" id="71982903"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03025"/>
    <dbReference type="OrthoDB" id="2190947at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.30:FF:000003">
        <property type="entry name" value="Signal recognition particle SEC65 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32215" checksum="B3D9165B3E4C05FE" modified="2023-09-13" version="1">MSNPRIEEVSDDEEIEVADDPDEMDLDAFDFARPQGKSLGQQASAEASASPSVPADMMEALLKGRPQQAGTGSTHAPQIARMNDAERQRYQREQQEKSKSYQCIYPAYFDATRSREQGRRVQKSDAVENPLAREIVEALANIGKDLNVALQIVLEPTKTHPKDWANPGRVKVLVKKDGRAVSAKIQNKHHLYKLISTHLKANPTTAETPMRLQIQGMPMPKDNKITPPAIPRGSKIGTILPLHSPALSGGGVSENFLKDMMAEMGGQLPPGMAGMAGAGGASTDSSQKKVKDKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7M2</accession>
    <name>A0A9Q8P7M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Serine/threonine-protein kinase crk1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760552.1">
        <property type="nucleotide sequence ID" value="XM_047903984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7M2"/>
    <dbReference type="GeneID" id="71984714"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04836"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="60"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="359"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="377"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO16186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="406" mass="45505" checksum="03025A9E2F4202B0" modified="2023-09-13" version="1">MAVPPKSPKSPALDVPPEPPFTRIKLSPQPPDSSARSSPSNGPVVADLAEHLDREERNSYIKGKLLGSGQYADVFSAHRVHDPSKLVAIKKIKIGAEAKEMGISYDSLREIKFLQELDHPNIIKLFAVFSTKNQNLNLVLEQLPQGDLLKLIQDFGNISYTAADIKSWMLMLMRAVHFCHANFILHRDIKPNNLLIAANGEIKLADFGLARSFADPYQPMTYNTITIWYRPPELFFQAPYYGGAVDIWSCGAVFAELITREVMFKAWPESEINMVKMICEKVGTPTEENWPGVSRLKGYVTPSDIIPLKSKDHWLGQFRAIGEVGVDLLMKMLTLDPRVRLDAEQVLRHEFWTAAPKPSKLADLPKKGGGLEQMGEDLERRGGEQPSKDESRGDKVARRIDFGAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7V9</accession>
    <name>A0A9Q8P7V9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7V9"/>
    <dbReference type="GeneID" id="71984929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05051"/>
    <dbReference type="OMA" id="PIFEMFP"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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        <property type="entry name" value="Thioredoxin_CS"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF06201">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
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        <location>
            <begin position="132"/>
            <end position="326"/>
        </location>
    </feature>
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        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="35871" checksum="CDF064AEFD7FAB81" modified="2023-09-13" version="1">MSKTVHVDSPTHFSSILSSSRIVVADFYADWCGPCTAIAPVYEALSSQLSRPGQITFTKINADEQKDIARTYNISAMPTFVIFKAQREVKRVRGADPKGLDAAVKQLAEEAGRADEGGADAGEGSSSAGKWTGAAAPRGYPEVTEEVEIKGLDFLNLDGEVGDKRTIFAPEQPSSLNAKGKSAEGKKDWIESDTDEQLMLYIPFQGTLKLHSLHITSIPPADDDDVMRPKTLHLYSNRSHVLGFDEADDTPATQTVEIKEDQWDAKTQTAKVELRFVKFQNISSLTVFVADGEGDGEKTRIDRVRLFGESGAKREMGKLEKIGDEQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P847</accession>
    <name>A0A9Q8P847_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_04228</name>
    </gene>
    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760943.1">
        <property type="nucleotide sequence ID" value="XM_047903376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P847"/>
    <dbReference type="GeneID" id="71984106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04228"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="115" mass="12817" checksum="DC772E4AB21381DB" modified="2023-09-13" version="1">MAANTNDVFGDLAIPNYVFLLAEKLHDQRGVLSIFGVPSAYAAPQTPQWMLNTITTDPGGPKGHIVISPDAEWDLLIELEGARSCYNLYKWCRAVHDDKGVVPRHVDTHSRSHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8R1</accession>
    <name>A0A9Q8P8R1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8R1"/>
    <dbReference type="GeneID" id="71985096"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05218"/>
    <dbReference type="OMA" id="ESKAGWW"/>
    <dbReference type="OrthoDB" id="5240110at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="261" mass="28318" checksum="09E947EE5ACB9012" modified="2023-09-13" version="1">MSSSLRPLIPIRSAGRSFSTTPPHHASILFALGALSNSRETQHFNNISRLDRVEHSPTLKLIKTSEIDPYPLPTPPQPAAPLPRHGSRATSAAAIWDSKALQAGRAILSDNARHLSRMARTIERTKRREMKMKHIRQSELAAWAQERQKMRAEQRSAGILILASVATATGLAMWRLWPEGGQAARDSGEMGRRIAERARRSIPLPATGSAAVPVAAGAAVAAESLPVTGVSTPIVPEMAAVAAEPAMSWSWTVKNMLWKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8R9</accession>
    <name>A0A9Q8P8R9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-dependent monooxygenase apdD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761557.1">
        <property type="nucleotide sequence ID" value="XM_047905567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8R9"/>
    <dbReference type="GeneID" id="71986297"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06419"/>
    <dbReference type="OrthoDB" id="2096480at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF21">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21274">
        <property type="entry name" value="Rng_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="4">
        <location>
            <begin position="490"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="669" mass="75031" checksum="1BC9AF44679AEE21" modified="2023-09-13" version="1">MSTGLTQDKILSKWALPSVDKFRTRISKNNDGTQPQEPWQRISQAIFERWLKSICDEDSLIDLRHGWKVTAVQETPGSVKTTVLSPEGEECGFVSRYLADCDGGSSRVRRALHIPIEGGPLPVRAVLVHFKSRGLRRLHKFGRFWHIFLTDRSGGFGEAIIAQDEIDTWTVHMFLHGDNDEDTGVLSSEEVVYRVLGGMHDPYPITIDEVLVRSTWRPVIAVTKDWSGPNRRVFLAGDAAHQNVPTGGYGMNLGIQDAFNLGWKLAAVINKSGGVGLLDSYEIERKPVAQRNVAHSGVHHRVHVQPQELLTRNGANPRHVDDDTDEARSTRLKVHEHYRQHDGENKDFGIEMDYRYCSPVICADESGSVEPSWSASQYTPTTWPGSRPPHLFLSTGTAIFETFGKDWTLLVFAKDACGQEYLVDSAKELTMSLSVVDLSGEQLAKKLYERALILIRPDQHVAWRGEAVGSAKDAHRVLAKVTWRQSHQPEYAGTRRSANCKLSANGRLYITFLGGHITYGNPVVTFLTYDEEHHRIAIVNRPETGPKQGKSSGLEHIAFTFPTMRDLLVAYRQRKQRGINPFWTVNHGPTTSLYYRDPDGNKLETQVDNFDTVDQANEFMSSPAFAENPIGADVDVEDLIQRFKSGEDEVSLKKRVEIGPRGLPDTDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC4</accession>
    <name>A0A9Q8PAC4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763182.1">
        <property type="nucleotide sequence ID" value="XM_047906527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAC4"/>
    <dbReference type="GeneID" id="71987257"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07379"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="47660" checksum="F753CA8E0F5FD5FE" modified="2023-09-13" version="1">MDESSSVGSVGKHSRGSSTATSSNDTAASSVSGAVNTKDDGTSFNKPWEVSKSPDATAIYSPWSDEWTDAAMGASTFPQQIESIQEAPKKEKKKSYGPDIVWICRATQLVPLMHLLFPGEPVFYDGEFVHFKLRILATGIIIFKQVLGRGAVVNSAGKPIYDVYPSYPSKGKFTKHYEILEKRFAPSKYMVELPDTWFENGAQPASEVEAELRVIFHGRPVVMHDHRGDTTAFLYETANSIMHDNGATIVDTQQLYAGAIPDAGDPSQPSLAKTCKFILGEDPQADGNHSPVKDADGVRKLWLALNPDYNRAAELAKLHATGWTPQRYPRQIPSTSAVEAELEAEVEVDKALIEAGLMVLLARAASTFVRRLPSTALAAISIPLLFAAAPLPMVVVAIGAVLLVVEATSALQQALSSSRILTSLPWEKSDGVAEHGTYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC6</accession>
    <name>A0A9Q8PAC6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763174.1">
        <property type="nucleotide sequence ID" value="XM_047906523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAC6"/>
    <dbReference type="GeneID" id="71987253"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07375"/>
    <dbReference type="OMA" id="TGWIMYM"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030729">
        <property type="term" value="F:acetoacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF4">
        <property type="entry name" value="ACETOACETYL-COA SYNTHASE (AFU_ORTHOLOGUE AFUA_8G04770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="3">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="129"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="703" mass="78432" checksum="61FB4A6E67AA22D9" modified="2023-09-13" version="1">MADTPVPRKLWDPPNPKGTMAYKFMQAVNQKHNTNLQTWQDLHAFSVDQRAAFWGELFTQHPLIHSGSYAKVVDENARMDTNPPWFEGVKVNFAENSLLWPDSKDPSKSTTYRKEDWRVACTEAREGGTEIRQCTWKELRERTAHMSNAMRARGVKKGDRVAVVASNSIDTLVVFYAVTSLGAIFSSSSTDMGTKGILDRLRQTKPKYVFVDDWALYNGKTFDLRPKMNELVDGMKGISELNCIVSIPRTQGKPQDISSVRCCETLANFLKSANGDKTLRFERIPFGDPFLIVYSSGTTGVPKCIVHNVGGILLNCRKEGNLHRDVAQTPPEDSCVLQYTTTGWIMYLSSCLSLMNGSRAVLYDGSPLQPDLTSFLKLIQDQGVTDLGVSPLWMQTLATAKPPVLPRDTVDLSQLRRVISTGMVLSEAQFEWFYDHGFPSHVQLENISGGTDLAACFTGANTMMPVYTGGTVSPCLGMKVEAYDQTIEGGKGVKGQPLPLGEAGEMVCTRGFPTQPVKFWDDPGGEKYFKSYFERFDNVWTHGDFLSIHPKTGQLFLHGRADGVLNPSGVRFGSAEIYNVIDINFVDEIQDSICVGQRRPQDMDESVMLFLLMKPGKKFSQALVNKVKDAIARDCGRRCVPKYVFETSEIPTTINLKKVELPVKQIVSGKTVKPSDTLANKDCLNFYYQFAKVEKVLEPKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM1</accession>
    <name>A0A9Q8PBM1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytokinesis protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR middle" evidence="4">
        <location>
            <begin position="663"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR" evidence="6">
        <location>
            <begin position="1069"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="121"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1280" mass="143538" checksum="73390D6F010B6B57" modified="2023-09-13" version="1">MTQPNPRANGPPAGTLRDNVLVPPSRSTKDGGSLSAASLLTAKQASHIRQVPPPPGSFTSDLKSFSSRLDLNSYGGGMEDGAVDPATSEQKQQEYRQEIEKHTRLKAGTENLLEALSTQKAKKAKDQRLAAESQLNASNRKIAQLKIDLEAEIQRSKEQPMSPKGRLSQLFRPSLERARVDAERMQIPAESPEQQDPELESPTYILAEILQALEVEDMQPDYYVNQANDLVELFRRHPTLKYDLAWSIFGLRMQVMLLSDSREVVAAGYRVIRYAITDRKSLQTIRGLHTDVLVILSLVKESKARVEREQAIKFVRSFLDVRDGIHEIHPAIVRIIAAVADHSDDQLRSIAILTLAEMLLKDPMLVVIAGGISVLSDAMGSGVYHAPETLIGPLLHLMDLPARRGVLRSGFEFSSAFATFTEPHASHLEERLVASSRVIAGMFKSWSGLMTLSLHDFLPVRSVVSSLYIADFRVRTATLDLLADILRLEKRSWSTPFIGGRRLTTYARVATLNLENDPSQHKKRETDNDRQKRNLVQHFIAVALAVLLRHGLLQALLHAEHDAPTDALRRRTNLIIAEVLKKASELLPTSWSAQLQTMPGLFNNAVKFDTEERHTALSTVYQVDKVNLKLWRSDPSTTTTKTYEETDGARARSASKTQATAEIDEVQFRARVLETGVLNTVNYLKWDWTIIQELIDGPLTNPKLLHEAVEKSKFVHRLLKFLRPFQFRFSDASNTKANQRYVKMSCTLVKTLLQTSEGANFLFNNKAIRQLAECLAQLDSESGITSKNPLFSPDRLSDTLVGGYFAMLGIMCSDSKGLQILERWHIINMFYHIVELKSRDDLIKCLLTSLDYTLDSHPRIILSKAMIAGSKHMRIMATRILRKYAIEPVEPMTPGGGPSEWAIKLLVSQLYDPEIEVCEVAIRILEETCNDFRSLEYVVKCRPALDHLGEIGAPLLLRFLSTSVGYHYLDGLDYITREMDDWFLGRNDSYVTVVEASLARALSDLPEKPQSSLDDTLGPQDFGYVPPHFYRELTRTAEGCELLKAKGHFEEFTATIQDFAMEDEDPETILKVKGCLWAVGNVGSMELGAPFLEHTDVVKYIVQIAEDSQVMTLRGTAFFVLGLISRSLHGQEILAEYGWDGTVNVMGESLGYVLPVDFEKLFSLQPFANPGRKSAILHSRPGAITDVEPQNQHILDSITKLGNTVLTNKALTELNGFKHKKVAGFESPALFRKVMILLASHAYRIPQYRFVIDLFDKSVLRKIVLEEDEDSDGTDSSRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC62</accession>
    <name>A0A9Q8PC62_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09896</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764121.1">
        <property type="nucleotide sequence ID" value="XM_047909044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC62"/>
    <dbReference type="GeneID" id="71989774"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09896"/>
    <dbReference type="OMA" id="WQQDVRV"/>
    <dbReference type="OrthoDB" id="6058203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01446">
        <property type="entry name" value="DSP_MapKP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18533">
        <property type="entry name" value="PTP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000051">
        <property type="entry name" value="Protein tyrosine phosphatase (Pyp1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF561">
        <property type="entry name" value="PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="6">
        <location>
            <begin position="263"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="513"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="705"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="624"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="860" mass="96534" checksum="1C3EBCF33BF00B0C" modified="2023-09-13" version="1">MTETAMATSPRHHSQQSRSQQRPSTTPSQPPAMTPFLSPRRPSPQRRSNGQSTPSPSYFGFQVDGSSMLSDSPQHAKSNWSPPSSTVRSTAAMSPSVVPLDQRPEFEAFRRQSEGKSFALGRLNNFKMSPPSIRPKQGRSSSGQSQQSPKQQTQPRDIPSASHRAALDPSTAELSRSPKRVLSPGSTTEANRKGSPPLDLNSAEARENKAEYDSQPRFKLPLGALNGSYNAQKARAETLPATKDTDSQVFATPQHVMTLINSKGDDILLLDLRVSTQYAMSHISGALNLCIPTTLLKRPSFNVQKLADTFKDNEQRSRFENWQNSSYIIVYDSSSAVMKDATVCLNTIKKFRSEGYEGSLYIIRGGFSEFAKRFPQYIEDGVDANSTAGVEGDGPEVAPVVGGCPMPGTDKPANPFFGNIRQNMDLIGGVGQMALKHPAKETRSAENEYPSWLKDAANERDQGKKVSNKFEAIERREKKRMEDALSGKVSWGATPKTPSVQEKVQIAGLEKGNKNRYNNIWPFEHSRVRLQNVPSHGCDYFNANHIKATWSNKRYISTQAPIPATFNDFWNVVWQQDVRVIVMLTAEKEGAQVKAHNYWDQKRYGPLHIDFLSEKRASLEPERIHKHQKRPSAMKRHSTQSKNPQVPLAPVDSKEDKSGEQPYVTVRKFTVSHDKFPFEPMREITQLQYSSWPDFGAPAHPAHLLGLVEQCDAVVRTTTRKQPAEPEPTSVRPILVHCSAGCGRTGTFCTVDSVIDMLKRQRISRDKRDTLPMDIDKKSPPRTFKESGGDFFASHFRESDDSLDGDWVLRDDHDLVEKTVEDFRHQRLSMVQSLRQYVLCYESVMEWIVEQRLEAKERSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC64</accession>
    <name>A0A9Q8PC64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10023</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764172.1">
        <property type="nucleotide sequence ID" value="XM_047909171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC64"/>
    <dbReference type="GeneID" id="71989901"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10023"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="39"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="39093" checksum="6729858904C84339" modified="2023-09-13" version="1">MSFSQIGLSSDASNDTTAATETTGFLMEAGRWSPLTSFQEDKKVVIKNVSIPEPGPNQFLIKIASASLCHSDIMAIDAGQTHTLGHEGAGYIEKIHQSVEGKGFAVGDSIGFLYIIGCCFECEGCMIHNTHCITGKQRVQGFTTDGFFAEYALVDYPNCIKLPGSIDVKTASPIFCAGITAFHAVDSSELKEGDSLAVVGAGGLGQLATQIAKAMGVKVVALDVNDGALEACKKQGADAVFNSKNNPDYIDQLKELTNGGVRAACVFSNAQAAYAGVPSILCLGGIMMVIGLPYDPIPISTMDLALGRYRIKADNTGIPQRMKKAVEFLAEHNIKPEVEHRKLEELDDMVNEMRAGKSIKRMLVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC80</accession>
    <name>A0A9Q8PC80_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Uricase</fullName>
            <ecNumber evidence="7 10">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 10">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 10">Belongs to the uricase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="7 10"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764151.1">
        <property type="nucleotide sequence ID" value="XM_047909011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC80"/>
    <dbReference type="GeneID" id="71989741"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09863"/>
    <dbReference type="OMA" id="ATMYKMS"/>
    <dbReference type="OrthoDB" id="9992118at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004846">
        <property type="term" value="F:urate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.270.10:FF:000001">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4 7 10" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="303" mass="34280" checksum="8FE8391AC81EE563" modified="2023-09-13" version="1">MASLTHARYGKDNIRLYKVHRDPSNPSLQSVTELTICTLLEGDISASWTHADNANIVATDTQKQTTYIHAKLNPVNPPELFAASLGSHFLKQYPHITAAHVDVKAHRWTRMVVEGAEHPHSFMRDGEEKRVVSAVVRRGEGIEVRSGLTGLLVLKSTGSQFHSFHRDEFTRLPETWDRILSTEVEAGWHWKTFNDLEDVKREQSAFDQAHEDARRITLETFARENSPSVQNTMYKMAEQILEAARGVERVEYSLPNKHYFEIDLSWYNGLKNTGADAEVYAPQSDPNGLIQCTVERKGAAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDQ2</accession>
    <name>A0A9Q8PDQ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764944.1">
        <property type="nucleotide sequence ID" value="XM_047910682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDQ2"/>
    <dbReference type="GeneID" id="71991412"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11534"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="34968" checksum="2A78FCBC2CCE0B50" modified="2023-09-13" version="1">MSEQMSKVAWPTLSLDVPNVYSAPATTLVTKASAITDKGHHPQTYGVAPPAYSSPAESPASPEAPAYTAPSSSSTAQAPVATSKTMEASIYSAPTTTSISSTTYAAPVASASPSAPTYSSTSSSSSGSTGLGNIYKMYTGTGEASSGWPSESTWISFDAAWTSNLDIMAKSCTQWGVPNNSDEENANLKSAIQSVAASSGVDERFVLAIVMQESNGCVRAPTTTYSVSNPGLMQSFKGTATCNPGTATAPQGQSPCPADSITQMISQGTNGSNPGDMSLVYALQKAGCDDVSKYYKAARIYNSGSVASDGDLAGGVATHCYASNVANRLTGWTTATCGCDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE30</accession>
    <name>A0A9Q8PE30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765177.1">
        <property type="nucleotide sequence ID" value="XM_047910082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE30"/>
    <dbReference type="GeneID" id="71990812"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10934"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="100" mass="11510" checksum="E0F3E14CE3C6AE1A" modified="2023-09-13" version="1">MECESGRSGPMPQDSALMASFETADNNFDASSAPWESFHSSILKLSPAQLRDRGLDENGWLEMIARQSRFFDHAHEFPSKCWNIEWGTRDRCKCPRIKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PES1</accession>
    <name>A0A9Q8PES1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Non-reducing polyketide synthase PKS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765457.1">
        <property type="nucleotide sequence ID" value="XM_047910608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PES1"/>
    <dbReference type="GeneID" id="71991338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11460"/>
    <dbReference type="OMA" id="WVEMEAN"/>
    <dbReference type="OrthoDB" id="3647642at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS/mFAS DH" evidence="4">
        <location>
            <begin position="16"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="3">
        <location>
            <begin position="16"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="3">
        <location>
            <begin position="192"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="3">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="38878" checksum="6EFDAF3D2513E062" modified="2023-09-13" version="1">MSTTTTTYTYLSASCQQVLESRLDSIPGTKVVVRSCMGDPRLSPTIIDHKCNGTVLTPSGLYADMAVEVGKHVWRHHRGQTAGLPGFNVCDLEVHKPTIVKDPTKIDEHWLEVETTASIPAGTRGDILDAVLKCAFYSITADGKRTQENGHCSVRFEWYYGWLSEWSNEAATINNRINTLHERGNKGGDSNIQIINKSRTYKLFQSFVDYTGKYQNMSEVVYDSATLEATSLLTFLADPATDCTGPYYLDGSCHISGFVANAVEKDKDKNAFISNGVSAMKLSPRFDPAKKGSVIRNYVQMKQLETDKTVLEGDVYILQDGEIVGVWESVRFKKIPRKVLNVFLQPPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF77</accession>
    <name>A0A9Q8PF77_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA damage-binding protein 1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765739.1">
        <property type="nucleotide sequence ID" value="XM_047910613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF77"/>
    <dbReference type="GeneID" id="71991343"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11465"/>
    <dbReference type="OMA" id="HQDFLMR"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000629">
        <property type="entry name" value="UV-damaged DNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="12"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="438"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="784"/>
            <end position="1105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1136" mass="124398" checksum="935605F91F32E84C" modified="2023-09-13" version="1">MAYLAPIHRPSSVRHALKLSFLAADSEDLVVAKANRLEVWSPASPTDPTLVHRHTKALYGKVTLLHKLRPATSQADHLFVGTDRYHYFTISWNPQTNDLNTERAYVDIAEKAARDSQTGDRVHIDPTSRFMTIECYEGVVNVLPIAHAGKGKRKAADNEIGELGEPIPVRIPELFVRSSCFLHRRQPTTKAVDPLFAVLHEDSTNKVRLKIRELEYSPSLRPNDEPAVAELEKGHDVEDSLELGASILIPLPPPMHGLLVVGETSISYVEEWQYQVTSTEPLDDATVFVAWCSLDDQRYVLADDYGKLYLLMVQKNAEGEYNGHQIDVLGITSRASTLVYLDGGRVFVGSHQGDSQIIQILEQSIEVLQTFPNIAPILDFTVMDMGNRSSDAPVNEFSSGQARIVTGSGAFKDGSLRSVRSGVGLEDRGDLGSLGAPISEVFSLRSSAATQLVDTLIVSFVDSTRVFVFDEEGDVEEREDFRGFSLSDSTLYAANLPDGRAVQVTGTSVLLADAESGVITDTWQAPAGITAVAAEQSTLLLSLSGKVLIALDLSSQSIKTQAQREFSSNEEVSCIALSSSIPDACVAGFWKDGKVSFLSLQNLQPTATERVAEDDLAVPRSLAIATILRDQPATLFVGLADGNVVTYTIGPLQKPFSARKSIILGTQQADFAVLPRGDGLQNVFATCEHPSLIYGSEGRMVYSAVTAESATSICAFNSEPYGNAIAIASNDELRIAAVDEERTTHVQDLFVHETVRRIAYSADLKAFGLGCIQRTLTAGQEEVRSHFKLVNEVAFKELASYELHEDELVESVIRCQLDDGSGESAERFAIGTAYLDDQDLNVARGRILILEVTEDRRLKLVTELKVKGACRCLAVCEGKIVAALIKTVIVYEFEYAASKATLTKKASYRTATAPIDVCVTGNVIAVTDLMKSMSLVEYKKGRTGMPDSLTEVARHFETLWGTAVANVADNTYLQSDAEGNLIVLQHDINGFSEEDRRRLRVTSEILLGEMVNRIRRIDVTPTPGALAIPRAFLATTEGSIYLFALIAPGKQDLLMRMQTNMAALVKSPGHVEFNSFRGFRNQVRDEGANGPMRFVDGGLIERFLDCGEDVQREIIKDLGIELEDARGMVESLRRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFU4</accession>
    <name>A0A9Q8PFU4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_09619</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766069.1">
        <property type="nucleotide sequence ID" value="XM_047908767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFU4"/>
    <dbReference type="GeneID" id="71989497"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09619"/>
    <dbReference type="OMA" id="ASYMARY"/>
    <dbReference type="OrthoDB" id="5852090at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="14">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="15">
        <location>
            <begin position="129"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="16">
        <location>
            <begin position="251"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO21703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="394" mass="43150" checksum="7DE4E6B87482D569" modified="2023-09-13" version="1">MAQTNGDGPHAGPKGRFLFTSESVGRGHPDKIADQVSDAVLDACLAEDKASKVACETATKTGMIMVFGEITTKTRLDYQKVIREAIKDIGYDHSDKGFDYKTCNVLVAIEEQSPDIAQGLHYEKRLEELGAGDQGIMFGYATDETPEMLPLTLLLAHKLNKAMDDAAKDGSLPWLRPDTKTQVTIEYEHDNGAVVPKRVDTVVVSAQHSADITTEVLRKEIKEKIIKKVIPAELLNDQTVYHIQPSGLFIIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYLARWVAKSLVHSGLARRALVQLSYAIGVAEPLSLFVESYGTSSKSSDELVEIIRKNFDLRPGVIVKELDLATPIYRQTAMNGHFTNQNFAWEKPRKLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG86</accession>
    <name>A0A9Q8PG86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766225.1">
        <property type="nucleotide sequence ID" value="XM_047908405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG86"/>
    <dbReference type="GeneID" id="71989135"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09257"/>
    <dbReference type="OMA" id="WESSQEG"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="318" mass="36359" checksum="196986E45E4DA12B" modified="2023-09-13" version="1">MGKKRVQACISVDIDAVAGWLGSYGGEDSTSDISRGLFAGTIGVRRLLKMFEKYNITTTWFIPGHSLETFPEECRMIVDAGHEIGLHGYSHENPQEMTLEQQTAIMDKCYKLITDFQNGKPPRGIVAPWWESSQEGAELMLKYGLEYDHSFSHHDCQCYWLRTGDEWAKIDFKQHPETWMKPLTGGPMTGLVEIPASWYLDDLPPMMFIKKAPNSHGWVNPRDVEELWMDQFNYFYREYDDFVFPVTVHPDVCGHPHGLLMLERIIEKINKHEGVEWVTMEQICDDFKSKSTAPTGALMPAAPGAILNDPNLQLQKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH57</accession>
    <name>A0A9Q8PH57_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766744.1">
        <property type="nucleotide sequence ID" value="XM_047908570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH57"/>
    <dbReference type="GeneID" id="71989300"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09422"/>
    <dbReference type="OMA" id="ANSERDF"/>
    <dbReference type="OrthoDB" id="3934090at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="535" mass="60732" checksum="5D1462CA145EE666" modified="2023-09-13" version="1">MSFRFQTAPIPPLNGLNHAPATTAAGEPSSDQPMNSTTSTQISMFPRQQLVPTVRRSEVSEEQRQAFITMPANNLDGEDSGDDDFHDAQEDPDYDFFNGFGANTQQNAAPPRDHQVGAFSFPQTYTAHTYQNAAPQQPQHSNGSGHVMDLTGDEEQEDTNFEYDQRHHEFDEVAIPDEDFRDLGFDLNQYQHEGAQQTADSSHHQARGGFSFDQQPYQTRGGFSFDRQPQQHQQGQMNGNDFPHEQPQQQQEHQYDGNYASDDQLRNMGILHPNTEDMGATSPNAPQDDDDLFASTFGSQTKDEDADSDIEIVDAPAFDAALKAKGFAFDPSEHSNGCIRNRIPTLPLPTQSTPKSTTPETRPARKKREAPEKDVYGQPFDGRTKIGPDYDRDLSDHLRKHFRFHSKVYDLVPRVPHWEDLDWNRRYWIAVLLEGKKPKNANSERDFVWMKGNRFSTVRTVWEKYVQTTLADRSGVLVMGYEQVEMGDRMEELDYFGDRLCVFRVLQPGHPDLGRAKSLVEGLVLEVIEIDLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI08</accession>
    <name>A0A9Q8PI08_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11786</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767196.1">
        <property type="nucleotide sequence ID" value="XM_047910934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI08"/>
    <dbReference type="GeneID" id="71991664"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11786"/>
    <dbReference type="OMA" id="CGGSTIR"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000037">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000073">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000023">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="538" mass="58652" checksum="388D1F8A2D685C16" modified="2023-09-13" version="1">MQAPVVVMNTATGDRKTGRQAQLSNITAAKTVADIIRSCLGPKAMLKMLLDPMGGIVLTNDGHAILREIEVAHPAAKSMIELARTQDEEVGDGTTTVIILAGEILALSLPQLERNIHPVVIIQAFKRALSDALNIVQDVSIPVDVNDNEVMRNLISTSIGTKFTSRYSDLMCDLALQAVRTVSHDAGGGKQEVDIKRYARVEKVPGGEIEDSTVLDGVMLNKDITHPKMRRRIENPRIVLLDCTLEYKKGESQTNIEISKEEDWNRILQIEEEQVKAMCDAILAVKPDIVITEKGVSDLAQHFLVKHNVTALRRVRKTDNNRIARATGATIVNSVYDLTERDVGTQCGLFEIEKIGDEYFTFLTKCKNPKACTILLRGPSKDILNEIDRNLLDAMSVARNVFFHPYLSPGGGATEMAVAVRLSQNAKGVEGVQQWPYKAIADAMEVIPRTLVQNAGASPIRILTQLRAKHSEGGSTFGIDGDAGKVVDMKDFGIWEPQAIKLQSIKTAIESACLLLRVDDIVGAKQAKTGGGGMGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF5</accession>
    <name>A0A9Q8PIF5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767351.1">
        <property type="nucleotide sequence ID" value="XM_047911020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIF5"/>
    <dbReference type="GeneID" id="71991750"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11872"/>
    <dbReference type="OrthoDB" id="3649348at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="178" mass="19294" checksum="577B063FBBFCE940" modified="2023-09-13" version="1">MLKHSARLATNIIQHSVNNKHFLSTTATPIVLCGVTSTMGSRVAPRMAPEYEVIQFVNSVARAKSEILALKTGKAVAPDPDNVGTHNFSKPPEAVVFGRGFDDKQVEEIRQACGGDTSELTWMMGKKEDREQMKASPPDFNKPGASDAYAEQSAAANKAALDKLKADGTWGDGQLHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIR4</accession>
    <name>A0A9Q8PIR4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11792</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767601.1">
        <property type="nucleotide sequence ID" value="XM_047910940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIR4"/>
    <dbReference type="GeneID" id="71991670"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11792"/>
    <dbReference type="OMA" id="PVPKWAQ"/>
    <dbReference type="OrthoDB" id="6123at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="9">
        <location>
            <begin position="1127"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="548"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1196"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="612"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="737"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="793"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1055"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1071"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1130"/>
            <end position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1239" mass="137092" checksum="25534F55442D9FAF" modified="2023-09-13" version="1">MATRTKAPPVGSSGWIENEREQADEFVGQEVDEFSFSVRNELEWLNEHMHDIFTPSQTNFADMFKTPGKLRGKTPRTARKVNALPPRQPLTDIFAPNAQPAPAYATKTAFYDKVAQFQIAEDVENRIPLNKPVSRATSPNRAAKAYIDSGYHGMMTDDEMELDAQTQLESIATSSQAGETVKVPLRDDQPPAQRVVKDGKEDETGASDDSFVSAKETENDAPAVTDEIMADADGDDQPAEIEEEVQDENVAPVQEQVLQREEEVKVSEAEPEHDVDTDMENGSPESDHSSPQKLLQRKSSFTFSALPAREPLGAKRSMGPLDRARSSFFSKSVSKPADVDDDEDETMQEKATEARAHSKTSTQLLHERLNMLGKTKEPRPSKSIHNITQTTSQPFYPQLPGAEPAGSQATDVFDQQALADQLTAAPVEDEDDDWIAPTKPAQVLKSKASEATIQQVTVDAVSPARPTMHQKSLSTMTIMSPEKANATAESRHQKATSVSHPNLAEALDSTTPAGSPMGKSQRDGPLSASKNRLWSALKSAKSIFASSASASAAAKLEAHNNSPAPHRSPKRDSGDHKIFNMPGALFSQNDVRASPARNNSIISFSPSRKTRSSTESDKRKEKELKAQQKAADQLEKERHKEAQKAAKQQAEELAKAEKAEKAEAARLEKERKQAEKQAASQPGRPGTAGTETASENEMPPPPPPKGSMLPSGKLRAPGRLARPTREPTKPAPMSIKVASQSQRLGSSALGKSQYESSAPPTASKMPPRTSSAQGHRPGSAQPTNSRVRALEAAQRKKEADERAAAEKLEKKRELERKRAAKAEEEKRAEEERKAAEQQRVHEIKLAAQRRAAEKQAAEVRKREQDRQDLQRREHEHQEQRRREQEHIAQQRREQEQLRQQEDARKAREAHELAEAIRRERAQQAQAHPRGDLPGTLRQLTKNTVPQPNPAKPAKRMLPTDEDDNPAATAHRPGMIRGPPSYQQADAKRRRTNEEQEEKGERRSVMAPPKRPSTLRKETLPKFSGYSHAPPPAAHHSNIYKAAVTSQHHNQHKPTHPSQLAQMSNARIPFGENQNPPAAHHASSSQMHPGYENAHPSKFKTPSRPAQAPKSAKSTPHYPQGDNIELPDIATDSEDESDEEEAGGGFRAPSWVASPALRDLLTQQQLVDPETVFGPIGELKMDEVFKNSKNQERLKRFRDRGSSAMWHETGDAVTSAEKRRDMEMRERVVRDGGWRYEPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIY6</accession>
    <name>A0A9Q8PIY6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767787.1">
        <property type="nucleotide sequence ID" value="XM_047912129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIY6"/>
    <dbReference type="GeneID" id="71992859"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12981"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="60" mass="6525" checksum="052CADCA98EB8BAE" modified="2023-09-13" version="1">MVRLTPDLGQIADPAAIIMVYSSAKSLPKHEWYDTFAGGIAHRGNFEITEEQVHAAAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ50</accession>
    <name>A0A9Q8PJ50_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767784.1">
        <property type="nucleotide sequence ID" value="XM_047912076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ50"/>
    <dbReference type="GeneID" id="71992806"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12928"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="679" mass="75317" checksum="F225F3CBCC4B88A1" modified="2023-09-13" version="1">MAPKNAPKRLQSLSPSSTDPTGRQKRTVTVLACNRCRLKKVKCDGLRPACATCNKHSQICRYDSELPRPTRQNNEELRNEGLNSQQQIARLHAQPDAGSSIVKNTLATRMIDVQASWLPLVPGITMPSPDARPSPHKAARATLPYTETSLEYELFCKHPDAYHIIEPYEHPDVVANTLLGFGSSPFRYGIEDSATHGPLKGVKLYESAALVISLYLENVHAVIGTFDADLFLGDLIARRLRYCSPFLVNALLYFGCQAYTAFNLAASQLSWEFYAEAKKVWQAADGMDSLANVAALVNMANAGAQNGHDQEGMHFLQVARSMAERLGLDDDTKPPAFLLRKLVPKPLTNDRRFHSHVAWGYFIMVNMYAFYYGMPPTRGSCNLPIPGSDQFPLPSYMGSSLTAVCKFWRICREVVRLYSGDQGTIPSRVPLAAMESRYQQILVLFSSDPAFKTPNSGRKPHHAMILHIWCHSAFITLMRPWISQSFFLRTFTSPASTPENIIAASIRQLKRLVTDFRLFYPEASYNIQWHPCLIFVANATLANSANDAEWKFYFMACLFGYGTLSPAYRVAELCFKGLLAMAIEEGKIPMWRARGLSRMLEQRGQGALVGGSYSGVRLKLEGAGREEVGTVEELAQRFEAAVVLGGDEGEEGGSGSGNVHGHGGSDDVVFDEFIDMEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJE4</accession>
    <name>A0A9Q8PJE4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767893.1">
        <property type="nucleotide sequence ID" value="XM_047912108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJE4"/>
    <dbReference type="GeneID" id="71992838"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12960"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="104"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="530" mass="58971" checksum="98319B9AB6534ECE" modified="2023-09-13" version="1">MLYTDPSSKSKQLCTPEHAHPSEHFLESLSFSRESDLLKMATNKPNDEKAEVYQHEVLSPTQTRDSIDDAKADVEGQSRMDYSGAHEKTDPKEIALVRKLDWYIMPMLWLMYWLNYLDRNAIALARLDNLEEELNLQGSQYQTCVSILFVGYILGQVPSNMLITRLKPSYYMSFCMALWAIVSALTALSKDFTGLLLTRFFLGIVEAPYYPGALYILGIFYTRKEIATRISILYTGNILATAFAGLIAAGIFEMGGLAGISGWKWLFILQGAATFVVAVASVFVLPDDPLNTRWLNEEERQLANARVVSDQVGAKGGQSTFAGLKEAARDPKLWLFAFMQHMHLAANGFKNFFPTAVETLGFSQLITLTLVCPPYLIAGAISIAWSYSSGKYNERTWHITIAKSVAIFGFVLCAATLNTGARYFGMVVFAIGTYAVNSIILGWVASTCGQTKERKASSLAIVNTIANASFVWTPYLWPDTDEPRYAIAMGSSAGFSILCAGGAWVMKFWLMRINRKIRQSENETVLAFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJL8</accession>
    <name>A0A9Q8PJL8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767950.1">
        <property type="nucleotide sequence ID" value="XM_047911681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJL8"/>
    <dbReference type="GeneID" id="71992411"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12533"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="13470" checksum="2C3E38C72C25C2F8" modified="2023-09-13" version="1">MSTSVVSSKATLRIPTTSLLNILPKVLHSSILTSRYHAAKSNDLVIQSDDSRKQNDNVTGCFRKLHELIVQAGRDAVPGETSVEQTKRVEQLQKAEAAGRRKMKELQSKKKSARRGGGGRGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJN2</accession>
    <name>A0A9Q8PJN2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13246</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the GAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768049.1">
        <property type="nucleotide sequence ID" value="XM_047912394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJN2"/>
    <dbReference type="GeneID" id="71993124"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13246"/>
    <dbReference type="OMA" id="KPQDGIV"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="126"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="155"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="22327" checksum="C2E53EA4F446AF27" modified="2023-09-13" version="1">MSFRGRGRGGGFSRGGGGDAGGRGGFRGGRGGFQQPYGPPDQVYEMGQFMHATEGEMVCESVNVKIPYFNAPIYLENKTPIGKVDEILGPLNQVYFTIKPQEGIQATSFKTGDKVYIGGDKLLPLEKFLPKPKPPPGAPKVKKPKGAGGDRGRGGRGGGFSRGGRGAPRGRGGFGGDRGRGGARGGSRGGFSGSGGFSRGGGGGFGGRGRGAPRGRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJW6</accession>
    <name>A0A9Q8PJW6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-related protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768131.1">
        <property type="nucleotide sequence ID" value="XM_047912022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJW6"/>
    <dbReference type="GeneID" id="71992752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12874"/>
    <dbReference type="OMA" id="MTEAPWN"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="477" mass="52167" checksum="16B347FF286A49B0" modified="2023-09-13" version="1">MASTLPPTQAPANQEYAGDEINALILDPGSYSTRAGFAGEDTPKSVVPSSYAVRDGSKLFGENAIHLYQPGLEIRNPYNSDGIVDDWDTASRLWEYSVTSRLTGSRQTPPSRNGLNNLSEQEKKDAEGDTAMDLDEQAEQLDDQEKVLGEYPLLMSEPAWNPQKAREKTMEIAMEEWGVPAFFLAKNGQLAAYSQGKATALVIDIGHLNTSITALWEGMVLKKGCVHTPLAGNWINEQLRLMFSSMSAPLTPHFMVKTKQPVDAGAPSNATYIQFPKPPTDSFRRLEEERVLTAFKESVVQAWGGPSRLENGPSQGATTNADYVRSLPPKPFEMPDGWNQVFGIERFKVAEGLFDSAAAYTDASHPAPSGEQTIVSAAKNAINACDVDTRPHLMNNIILTGAGSLIAGLPERIQSDLQALFPNPKIRVIANSNSVERKYGGWIGGSVLGSLGTFHQMWISRQEYEEFGAAIIEKRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK13</accession>
    <name>A0A9Q8PK13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Galactose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_13232</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768312.1">
        <property type="nucleotide sequence ID" value="XM_047912380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK13"/>
    <dbReference type="GeneID" id="71993110"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13232"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF77">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="57607" checksum="82AD136BF2717F12" modified="2023-09-13" version="1">MGGPANAGGLNLNIKWSEHQWAILYCLVATIGALCYGYDTIYYTGIQGMQYFARDYGDQLSDGTYELGTTFLSVSASIIYVGEFVGALLAAPINDRFGRKAVFICASICIIIGAVIQVCAYGIAGVFYVGRIFVGLGVGQFTATCLMYVADVAPSAIRGPALMMFQFMQSIAQFVGACVNQGTETIDGQAQYRLPMALLVVLPLTMLVLLTITPESPVWYMAKDRREEAKRSLEKINRSNPNYESETDLKVIEDQIALDRDMAAESSWPSLILDPVERRKLIYACGVMFAQQINGIQFWYTYGVVFAQSIGVGEPFTINTIIYVVQIITVGLSVIFGNKMRRRTNLLVCTIGMLVSLVAVGGLGVTKDSDGNFSRGVGIGIVVFAYFNIVFYNFSIGTLSYTIASEMAVGRNRNKITACALGTFFFTVWLMVFTSPYLYYDAELGPMVGFVYAGTTLFTLAYAWFCVGETTGRTNAELERFFVERIPVRSWRTHVFADADIGSVYSAENEKDQAVDARVEEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKA6</accession>
    <name>A0A9Q8PKA6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768399.1">
        <property type="nucleotide sequence ID" value="XM_047912426.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71993156"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13278"/>
    <dbReference type="OrthoDB" id="3641063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1417"/>
            <end position="1491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1956" mass="218529" checksum="C99B7ED39EA1A4B2" modified="2023-09-13" version="1">MPTTSVDREQSYHRISTSSVMASWDGVAKTLKERLDWHVDRCNHMITTPLPVRLDSGALRAALQALQERHPILCAKSGLAGRHTHANYQELHTINTDRPDHGLDFVKRAHQELCKPFDDTEPRWRAALFRDDKDQWLLSIVMHHEDFDRYSLRVLWHDFTKICRAIYHALNPFSYLEPLALGYEGDGIAGCRAQGIRASDTDQQVRYLAKELDGSRAAGLLIDKPRPASPRGQMAAYEFRIEGRTYHVLKDYCRTHQVTHSALLRAAFRAAHYRITGMEDSVIGTCISGRDQQRLQHQIGYFANTLCLRLPVLEEDTFGSLVHYAQGAFKTALEAEDVSSRKLRTASLSEERNGTHSDSPSLFFNVHDQVVIEAKMFGEVDGEAIFMPGLCAKLATDCDLEVNIDADVDHFEGVALYDVDLFTKDTIRGLIGVFLAILRHALESANIPVGCIPLQDDTCDVNSERRLEQQNCDSTRESSIVDIFTETAASCPDHVAIKDITMQLTYNQLHERSDHLARWLRWRGLAAETLIAVLAPRSCLATIAFLGILKANLAYVPLDVNAPAGRFETVLSSLPGQKRLVLLGADVQIPEMSLTKGSADFAWISAALVQPAEEVSPCDIEYPSASSLAYCMFTSGSTGKPKGVKIEHRGVVSMAKHNNFTIAKTAHLSNLAFDASIWEIFVPLLNGGTVVCIDYLTSLVPDSLCEVIKNERIQAVMITPGLLRQCQEVHPTMFRSLHSLYVVGDRFDPIDAVKISHDLDGTVFNAYGPTECTVISTIYEVQKQDSFPNGVPIGKAVSNARVHIMDPKQRRVPAGVLGEIVITGRGLARGYLDRALEAGRFIDIVIDGEQERGYRTGDRARYRLDGQLEMFGRMDRQTKVRGHRVELAEIESAILCNKQVSDVAVVRCEQSTPDSAAMVAFLVAHEDKSTGGTEHGEHISAWTEHYDSTTYSNLQDVELDSLGHDFVGWVSMLDEQPIPKTEMQEWLSDTIATITDMQEPGHVLEVGTGTGMILFNLRKGLRSYVGIEPSKRAAEFVEKAISSMPDLADRVKIHVGEASDLDGLTDIHPELVLLNSVVQYFPSQDYFTQTCTTLIHLPGVQRIVFGDIRTFALYRDFLASIAVYKLGNEARKSDVRQYIADKVDREEELLVDPAFFYVLQDRFPSVIEHVEILPKIMPATNELSAFRYTAVLHTRCPEEKARQIHEISESAWIDFRALGMTKDTLSHFLGTSSHAPIIAVRNIPHSKTVRERYLVEALDSQDPETNGEASWISTAADAARQCASMDALDLIEIGRRACYHAEVSCARQFSQRGGLDVVFHRQQSSCEGARVLFKFPSDHEISRRMTSSPLVLSQKSKIVSDVLTDLRNRLPSYMVPDRLHLRDRLPLNANGKVDRKELTNQALSLQQEQRTKHGPKTPCNKLQALLREEFEAVLGVQIDIDESFFDVGGHSLSAIRLAAKLTSRCNAKVTAKNIFASPTVRGLAQVLTDRLPDYEGRHISDDRHGSYQPFGLISTDVPDDFVDRELLPKVQHLETKVIDAYRPTYAQRLFLQAGKSGKSLGADTYYLDLPADVDRRLLEKSCRAIVERFDIFRTVFVRVSNGIYAVVLENGMVSISLQNTDGDLDDALASTWTTDSQSLTNAEPLLHIAIIAKPDVTVRLAFRMSHAIYDGLSLEHLTNTLHCLYTGLSLPPASSFTTYLQHAYSTRGLGREFWRTYLQSSTITSLRNDEESDDSEASYWAQHTIRVPRSMLINGITQATIFTTAYAQALAKETGSNEVLFGRLVSGRHDLPGDSTAIVGPCNAIVPIRIRLQPETDVSTLLNQVQTHCLDSLSFETIGLDDIVANCTDWPHDTQHLWSYVLYQDFSTQSMFAGKEVAWKNLPYRGPPIHELDVGGVVDQDSGDFTVFMYARRRSCSEEVVDRMLRSLCQSFLKMSGGGGEDHDIVAQPDYREKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKI5</accession>
    <name>A0A9Q8PKI5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768487.1">
        <property type="nucleotide sequence ID" value="XM_047912304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKI5"/>
    <dbReference type="GeneID" id="71993034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13156"/>
    <dbReference type="OrthoDB" id="10561571at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="85"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="45563" checksum="4CD4BEAA6D9F0F4E" modified="2023-09-13" version="1">MSPKKTSTTEALLAPTSFLSPQDAKPSTESKEVCTSSPHLLSSIVRPDVVFDVPTLSAAPSDPESGQFGNDVILSTWRLAYGPDRSHLLRLPNETLLHAFTHLRLQDMIQARLVCHFFRGLIDYHCDYDILVLEPQFYYTPLEMLASNAQHDILQFDYLEILAEMVARRALCSSRKYPYILTIYVMMDMFMRRGPDSDVGTQKDTWKAFWELGYTIWQTHIQKHSPHHGLICSNWEPCEDVGDFVNRAHHPVLDQFGITRAKLDLWYGSLVTTPGGYLRGVPGPRRAKDPWPRPILSHLCLTGLYAYDGESSVQPTSYGLMLHHRPPVMPDASTRLANLLGIAELPTRFEAFGELFEDGYAFAWCAHSQHVYGMLRAALRSQSGRRLTRLGKAMFMEGIYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL68</accession>
    <name>A0A9Q8PL68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Aquaporin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_13537</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768836.1">
        <property type="nucleotide sequence ID" value="XM_047912685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL68"/>
    <dbReference type="GeneID" id="71993415"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13537"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO24470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="398" mass="43183" checksum="A46CAAE3B9971ADE" modified="2023-09-13" version="1">MDRNAQTTATDRSSSGEKSLHSHEKDEPLRPVSLHSIPTIDISHHEHAQEQTLPPGEKDDVDTVRTTSHVKGLRSRLGLMPTAPIIGEHDTADHANLWWPKTRAAFKEPLAEFFGVMIMVCFGNGSVAQVLLSAGMTSAPGMNGYGSYQSISWGWGLGVMLGIYVAGDSGAYLNPAITFTNCVLRKLPWRRFPIYLLAQFLGGFVGAGIVYANYINGINTFEGGAGLRTVPPAANATGAIFCTYPQADLTKASQFFSEFIASSLLMFVIFALKDDSNKGTFSASGSWFPLGLFFLIFGLGAAFGWDTGYAINLARDFGPRLMSYAVGYRGVWSAGGYYFWIPMVAPFCGCLFGGLLYDLAIYTGPSPINEPWLGLRNVTRPKQALGSRLQAQEKDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLZ0</accession>
    <name>A0A9Q8PLZ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769238.1">
        <property type="nucleotide sequence ID" value="XM_047913278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLZ0"/>
    <dbReference type="GeneID" id="71994008"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14130"/>
    <dbReference type="OrthoDB" id="3650837at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="61990" checksum="191CD06C82DD2566" modified="2023-09-13" version="1">MAPPSQIISPADASIILKHAASSCGHDECPDLIHTTNAAEGQEPVLPLYLRSPEHFFNRDLDCACPESDYENHTGGCECECECEEECDDDYCVDECGCEPCLAEKSACSPRLRLERPEGIRDIFESVYTNRIGPYRIAKDHQLDYQLCTARELKGFVDARGLQDLYPAGTTLKPLYIRALQDADRKATFRFLDLPAEMRNLVYAELLTFDVETCPHRRMCYAQILRTCKAAYVEAKEILYDNVVDVRFSAQVKPIEHAGGNDRLETGALVHNTLVTQRGKTDFGRLLNCTAIYPDFLKRITQLKLSRSLTDDPSANRLPEFAHRGLAYLHSCLVTLTSFLMDQHCLHSVQVDITKLGRLEDEELIATLRPLRRLRNVSSMRITGDCREELKARIANDVNGTASVPNTLKQMQLVISHGQAAVRLGGLTNPLFGHRPCGSYPSECGYEMVDLVQQHLDAILCGADDRYAHFGLFESARKEKILQIRLAKIQDALSDLHMDMVRKNLELLEKAKATKDEYFDGRVDPDETKLLAGYYTDYETDYDSEDSEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PML0</accession>
    <name>A0A9Q8PML0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769513.1">
        <property type="nucleotide sequence ID" value="XM_047913742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PML0"/>
    <dbReference type="GeneID" id="71994472"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14594"/>
    <dbReference type="OrthoDB" id="5422863at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF63">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="365"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="582" mass="65422" checksum="B344292582181990" modified="2023-09-13" version="1">MTLANESFAHATGYAHHQHEHHITGAHLIGSVPLPDAEAVFRQCAANLPARLKRIPDGETGDRQLFTTFQAQLFGIYPPMMTEFVHNAPIQDKHFTPEQIQEGIDILTKVDLHTGYDDVAIESYAIFRRLKDEGVIPLDVKFQVSLPSIPNVIGPFVQHAFQAIVEPIYEAALFRAIRRIQERIPHEDLAIQIDIALDTAYWEALNPDTVRENSGLEWFRPWFKGDVKQYQTDYIVRFISQVDDDVEVGLHNCYGDMQHQHWHEPASLAVVVERALWVYSASPRKINFFHCPVPKSAEGHIDAYLDPLKYLLPVLRQHETDLYLGLVHEHKPDLTKKYIAAAKKVVPIFGVAAECGGGRTPWEDFEDVLKISKDVSEPVVVVDAASTHRSKYFNNAVINQWFDSPPVQDQGHCQDEDCHVDGLKESRTYLKNLVDAEVAVVGAKNVFIGGFSQGCAMALHFLLSSEGELGGFVGMSGWMPMVQSLEKTLEQEEDAPTSVCNFVRETMGLRPLEVAPYLATPVLLGHGTLDDIVILSKGQRAAAFLRDLGMQVTWKEYAIGHCYEVSRQIDDIVAFLQRRGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PML5</accession>
    <name>A0A9Q8PML5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Versiconal hemiacetal acetate esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769582.1">
        <property type="nucleotide sequence ID" value="XM_047913404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PML5"/>
    <dbReference type="GeneID" id="71994134"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14256"/>
    <dbReference type="OMA" id="HCFWIVP"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="81"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="34944" checksum="E2E6B1C904C069DB" modified="2023-09-13" version="1">MPGEYATSWLDWEAQSGGRAIMHGTPDEIKGMYEGLVQALMPMAPPFSENVDVTEGDVEGIKYRIYKPKGVEGPLPIGFDTHGGGWMTGDLNSDHILCGVIAEHTKSVVVNVDYRLTPEVAYPVPLEDCLKGYKWAAANASSFGGDPNKFYTIGGSAGGAIALQIANKIKKDPALGPGLKGVVAIVPATTHWDNVPEKYKSKYNSYTENKAGTPIIDKESMEIFYKYAKVDPKDPETFTILAEENHKNFPPTYFASCEFDPLRDDAYVMEAALKEAGVPTKHDHYPGLPHYFWIIPAVPEGQVFIGNLLQGIGWIQGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMS2</accession>
    <name>A0A9Q8PMS2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein mgr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_14240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769658.1">
        <property type="nucleotide sequence ID" value="XM_047913388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMS2"/>
    <dbReference type="GeneID" id="71994118"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14240"/>
    <dbReference type="OrthoDB" id="5409308at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO25292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12318" checksum="901B05C6663ABE38" modified="2023-09-13" version="1">MPPVAGAGGMAGPSTIDKAKMGAMMGGTVGLCIGFIFGATNIIRFGPGPNGMMRTLGQYMLGSAATFGRFFMSIGTTIRTESSPIMTEAFKASQMRHGRPTIAEHMQRRRKAQQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQM1</accession>
    <name>A0A9Q8UQM1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="10">AK6</shortName>
            <ecNumber evidence="10">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="10">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_07652</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="10"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763244.1">
        <property type="nucleotide sequence ID" value="XM_047906800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQM1"/>
    <dbReference type="GeneID" id="71987530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07652"/>
    <dbReference type="OrthoDB" id="10251185at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000372">
        <property type="entry name" value="Adenylate kinase isoenzyme 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="LID" evidence="10">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO18878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="227" mass="26002" checksum="5350629DD48F53A0" modified="2023-09-13" version="1">MFPRTCTRLVTPLLHRPTHLRRLATLSKMLRTSPNIIITGSPAVGKTTHCEELARKTGLHHLSINDVVKKHNIGETSNDAEDPQVKIVDEDRLLDCIEDDLEEGGQIIDWHACDLFPVSLIDLVCVVRCEDTMKLYDRMKARGYGERKLQENLDCEIMQVLLEEAREAYAPEMVVELKSEDADEVESNVERVEKWIEQWRKDHGKEGEVKAESEGKKDEDDPMFLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQN3</accession>
    <name>A0A9Q8UQN3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Subtelomeric hrmA-associated cluster protein AFUB-079030/YDR124W-like helical bundle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763218.1">
        <property type="nucleotide sequence ID" value="XM_047906782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQN3"/>
    <dbReference type="GeneID" id="71987512"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07634"/>
    <dbReference type="OMA" id="MAEDKMP"/>
    <dbReference type="OrthoDB" id="5338458at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047092">
        <property type="entry name" value="AFUB_07903/YDR124W-like_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021264">
        <property type="entry name" value="AFUB_079030/YDR124W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36102">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36102:SF1">
        <property type="entry name" value="YDR124W-LIKE HELICAL BUNDLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11001">
        <property type="entry name" value="AFUB_07903_YDR124W_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Subtelomeric hrmA-associated cluster protein AFUB-079030/YDR124W-like helical bundle" evidence="2">
        <location>
            <begin position="165"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="683" mass="78152" checksum="4267818515CAE650" modified="2023-09-13" version="1">MVHIPQRNMKSQMKRDRVQSVDKQKRMESIRRSWELTVMQALARKKINGQSFLVNTDSEGNVTNVQVQSSALSTRSQGTGSSRHDQTSAMDQDEDSTDDELFSQPITRARGKRASRATRCRDRSIVRGNTTRKSAYPYPQPTAALTSESDDEPPIPPRKQHKSFQIQDEQAVKDFLHSRLKGMQQLADKKIAKAWIKSICPKKQANFPYQNKKTGSDGRVREQPPKVPGWWPDTEACRFIEPDHIKRTERMDLCLHLLRLRPDPEQLRIWNEDKTEPNPIHEYQGWTAFLKDSAGAEIFDELPKEDKVRTEKRKYLMEQMYDVAQFEQDFLDGGVDGTQEYTYEDNEEEKRLAPVKRARSVSANFCGDRASRQSSASVGCMRTKRVRQVTPSNASILVPSQVQTQKVEFEQPELEAPEHIQTREQSVERFFDFTQADHGYDSVMADNFCTSKAEGRSRRSNPFIGHCEVVDLKREPSVEHNRQFQPQSPQYQQQWAKYEQDPMQWTAQPPAASSFMPSQGNHLAGTEAYHHHSQPASTNFPGRQDFVFPQFPAPGMIQVQQINQIPEPQFQAPPNTPIYSPQSMAPVPLNSYVPFDSHLSQEAPYTTSMAPNQFFMPAFETSVPAFHPPTTAAPQQIHQEPAPSHPQYHHHQQPQQGLAQRHIIPTRYHGLPFTQSNGWPASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQY8</accession>
    <name>A0A9Q8UQY8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="45195" checksum="91D63410E33F627F" modified="2023-09-13" version="1">MELESRPIDVSHHCGLLIPSIKPLEISNEDTLCRASLAGRHAKLYVAADLSPAEDALKKATLDVASVMKCFPAVTSEAIILAMAAWYTTLCHIDDAVENLESEAAQLALAHAIYILRNASWCNPPMPGETNHEGDTQDMFMARVLSATVAYCSRLQDLLPCTVQSKLRAASIDTLDALALEHKWRHRSSINESAYLSIRTKTIGVTPFFLLVRYNFDHDSSFLTQNVELESLMSDAELAIGLQNDLIGLSRDIEKGERFNYILRLESPSLDEREARTLKAVNIHNNAIRSATATWENLKAGSGASAQACADSLMKFVERHYLWASTSKRYQCHPSGHRQLPQKSRLSLLVMRALLAKSSMRKNLGLDVHYPDNGRRKRKASLQEWTIRMELKQAMKSTKETSLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI0</accession>
    <name>A0A9Q8USI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765225.1">
        <property type="nucleotide sequence ID" value="XM_047910645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USI0"/>
    <dbReference type="GeneID" id="71991375"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11497"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="487" mass="53833" checksum="D639E9A031E7A270" modified="2023-09-13" version="1">MATSIDLEKQKTHNQHIEKLPQLERVDNLSQDSEKPVSTDYAGAHAKTDPEEIKLVRKLDTWITPTLFSMFFLNYLDRNAIALAPLDGIKDELNLTGSEFQTCVSILNVGYLLGQVPSNMIITRVRPSLYVPGCMAAWAVVSTLTCVANDFKGLVLCRFFLGITEAPFIPAAMYLLSVFYTRKELAMRVSLLLCGSVLSTAFAGLIALGIFELGGQSGLTGWRWMFLIQGVITFAVAVGSAFTLPDEPLTTKWLTPEQRTLAHNRILDDTVEAQASTSSWQGLKDAAKDSRLWIFTLALHAERVTLSFKNFLPQVIETLGFDRAITLALICPPYLVAVFVMVGWSWSSGHFNERTWHIFIGKSVAAIGFIIAAATMNLGARYFAIILFVGSINAVDGILFGWIAVTCGQTKEKKASALALSNAIATAAMIWSPYLYTDKPQYVKPMVTNACLSVFVAACALLLKWMLKRANKKLKEQNAEAYLFYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USQ6</accession>
    <name>A0A9Q8USQ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_10806</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765404.1">
        <property type="nucleotide sequence ID" value="XM_047909954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USQ6"/>
    <dbReference type="GeneID" id="71990684"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10806"/>
    <dbReference type="OMA" id="FHVNGKW"/>
    <dbReference type="OrthoDB" id="271553at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="116"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="409"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="728"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO21038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="759" mass="85245" checksum="9E4C2873F983DE8A" modified="2023-09-13" version="1">MDPERLLQLPGELLFLWHTHRAEVLLGAAVVIGLLRLAIQWRGRKSKIALTPPLGSPIDEKKQTFAVEHSREVSKEPVIADKVEPAVASKGPRRIKGKRIPRPKQDTGPAIEQIQPYVFYFSLGGSTREHATKLVEALSAKDDSQRILQPALHDLTEIDYEDYFVSPPKTSSPSTANFYMILIPGYNIDTELSNFLSHLEETHHDFRIDTAPLSGLAGYSVFGFGDQSEWPTERDGYCQQAIEVDKWMARLTGRKRAFPLGMRDVKADELEERLTDWRRGVQSVMQDLSQGKGLGEGVAGSGDAVESDDEDAVEYEDDETLVGKPRKNRKVGDDLEDMKAPIPVDFTTAGKSASTLQTPKEMVPKTSPTYTNLTKQGYTIVGSHSGVKICRWTKSALRGRGSCYKYSFYGINSHLCMEATPSLSCSNKCVFCWRHGTNPVGTTWRWQVDPPDLIFDGMKEGHYQKIKMMRGVPGVRSERFSEAMRIRHCALSLVGEPIFYPHINELLAMLHNEHISSFLVCNAQHPDQLAALGPVTQLYVSIDASNKESLRKIDRPLHRDFWERFIRCMDILREKRFTHRTVFRLTLVKGFNIEEEAAGYADLVERALPGFVEVKGVTYCGTSTAAGAGLSMQNVPFYKEVQKFVLALEAELNRRGLQYGIGAEHAHSCCILLADRTRFNKDGRWHTTIDYPAFFKCVESGKPFSPEDYIGAPTHEWALWGNGGFDPRDERVDRKGKPKEVKAVEYPPGSVPGSMVMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT61</accession>
    <name>A0A9Q8UT61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="13">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_09263</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="13"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765869.1">
        <property type="nucleotide sequence ID" value="XM_047908411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT61"/>
    <dbReference type="GeneID" id="71989141"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09263"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF12">
        <property type="entry name" value="EXO-POLYGALACTURONASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO21503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="359" mass="38573" checksum="009B06BA516EA78E" modified="2023-09-13" version="1">MHMKLQNARLEVFGTLSFEPDLLYWIQNSFRIEFQNQSTSWIVEGHDIEIDEGGWAQGGVNGNGQAWMTRTQGRSNQFGRPIPLTIFNSTNVSVKNFSIRQPQFWTFYAQDVQHLEMSGIFINGTNTDPAGNRSNYETNIDGFNGVRVNHARLADWYFHGGDDCIALKGNSTNFAISNITCLGGGIAFGSIGQYKESPDFVSNVTAQDISVAKDIRPPTGGAGVSGGAYFKSWVGVEAGQPPQGGGGGTGRVDNITFTGLSVQNVTNAIFVNKCYFKVPSQAQHCDTSTLVFGDLTFSNVSGTVKGSTGVSLNCSAAAPCQDIKLEDVRLASVANKSVALTCVNAKGLMVQPVTARCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT84</accession>
    <name>A0A9Q8UT84_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766005.1">
        <property type="nucleotide sequence ID" value="XM_047908265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT84"/>
    <dbReference type="GeneID" id="71988995"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09117"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="40017" checksum="1753C185FE7F240A" modified="2023-09-13" version="1">MADTNTNAPAEAPRPVETASAIAPTLLAPFNADEDDADSAYGGSVAGTDTTSLLSPIARYREENGRTYHSYGTTEHWGPNDDKAQDQQDLSHHLWGLALKGQHFLAPVEPENVLDMGTGTGIWAMEMAEKFPDATVKGIDLSPIQPTWVPPNLFFEVDDYNMDWLDEEQFDLIHARELLGTTPDWPGLFRKAFKALKPGGWFEQHEPSLFFLSDVVKLEEDHPFPKWGQLMVESGEKAGLRFDIGAELKGWMEQAGFVNVTEYRMPWLIGGWSEDKHQREVGQWNQLRLDLGIADFCSRRFHNQMGLSPEEIEVFCARLRLAFRDKRLFGYQWAYFVYGQRPPTDPKPSILQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTY6</accession>
    <name>A0A9Q8UTY6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trans-enoyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766623.1">
        <property type="nucleotide sequence ID" value="XM_047908163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTY6"/>
    <dbReference type="GeneID" id="71988893"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09015"/>
    <dbReference type="OMA" id="FQEYAIV"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="71"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="446" mass="47914" checksum="F0904B74D825FEF2" modified="2023-09-13" version="1">MSVEVQRLPLTSAFYDLDDALQKDIDWGTATPISHDEHIESDFSSAAYKRGTKRPAVVDVIPSHQKALLLHELRQPFVKQDHAVPQINGPEEILIEVQAIGLNPIDWKSVDYGFGIPVLPYVSGRDFAGVVVKAPLSKSHIQEGDTILCPSTDYRDLRKAAYQEYAIASHSTVCRLPRHVSTSQGAAIGVAYVAAALAMGVCLGLPMPALGSNTGPDILDIVRSTPLGSLPADTVAECIAIKASERPKAGDWIVIWGGSSTSALFLSQIAKLAGLRVILVVDVAKHGAWLIDTSGCVCIDSHDAERAVHVICGIAGSDLRFGVDTVGKETSEHLAQCLAHDTKDGSTKAHLVGLAALPKQRKDGIVYHSVPVKLFHEVPRVGSSLMSWLEEALESRAISLPRIEEAPGGLEGINAALDRMRQGHVSGKRLVVPLPWRADTISIYPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU02</accession>
    <name>A0A9Q8UU02_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08816</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766668.1">
        <property type="nucleotide sequence ID" value="XM_047907964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU02"/>
    <dbReference type="GeneID" id="71988694"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08816"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="200"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="31519" checksum="80056CA71DB6C616" modified="2023-09-13" version="1">MAKPTISLDHCRIPSQPDKVPHLNGQPLQIIDNTADNTEDLSPAIGLATVLYNWCPDALYAFLDLESWFSFTWTLTPDLGEPSESKLEIGRIRNQITFGKLDNEGHWKLMIAYDLDENGIWHPNLKETMLDDADVTTPDQINRLAQQFASDLVREKRWLTGKKMKHEFFIEFAPMEDSIWDDGIAMSPHWLYKALDLNRCTTCDAQAGESEALSRCRRCGTAAYCSDKCQKQDWPVHKAVCSMSLDERGKALHLTKDGGLIRWVQAGMKPLYDIEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU23</accession>
    <name>A0A9Q8UU23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766799.1">
        <property type="nucleotide sequence ID" value="XM_047908816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU23"/>
    <dbReference type="GeneID" id="71989546"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09668"/>
    <dbReference type="OrthoDB" id="3647333at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="610" mass="68818" checksum="AC9BFADE084628DB" modified="2023-09-13" version="1">MPHWYDHIKRAESLWTREERVNNPRWKVLFDLLDRLVYERTEDFAKCQALLFNHREVDEHLGLPWDRGTWKPLHIAAFLALPSWTEHLLDRGESLEEISNDRTVLQAAAKGEGSKEILELLLQRGADSNAETDKRMPAVHSWLWTLPSYECMELFVRHGAKLDTIDKVNGWSVLHYFADTAEDVKVLDLLLKDDVNGNHADINAKDEAGETPLHVLMSRREVPADILASFIDRGANVNVEDKDSERPLYEASIAGDHAAMEVILLSVTDIDDPNDYGRRALHQAAWSGYTDCVKTLLKWKADPNILDKHDRTPLDDVERRLTIEQADLRKGRTALHAAAYWGQVGSVRLLLEHGADATIKDKDGKTALELACARWVLSGQQHFEDTIELLVDKDPTSAVNDRDLHSSAAANGSKRILEKLHHLQADLTKPDDFGWTSLMLAKGFGHTDAEKFLQRVDSARVETLPTRWVNMPAHVEVDATGTVLKCSSTDIPPTAISTDKPLRGDLKSYYFEVTSKKMDGVEQATYPERPHTQSLPSASVRWEPQLEVFLAGNRVSTLPMRAPSSGEVEERDELRCEPGDTFGCGVDLEANTMWVTKNGEKIEMDFFKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU93</accession>
    <name>A0A9Q8UU93_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation factor IIA large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12071</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767057.1">
        <property type="nucleotide sequence ID" value="XM_047911219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU93"/>
    <dbReference type="GeneID" id="71991949"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12071"/>
    <dbReference type="OMA" id="EVCDASQ"/>
    <dbReference type="OrthoDB" id="6275927at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07976">
        <property type="entry name" value="TFIIA_alpha_beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000006">
        <property type="entry name" value="Transcription factor TFIIA complex subunit Toa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004855">
        <property type="entry name" value="TFIIA_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03153">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01371">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="410" mass="44595" checksum="2E6B38591019A6C3" modified="2023-09-13" version="1">MTNTLVGDVYQKIIEEVVSASSNDFEESGVMGSTLEELRQEWQAKLSARQVAQMPWDPKPQPPVQQPPPSHMPSAAANGMPPQAYPPNPYATGPGSGNERIKMEPGTEQQQYNGLPNVAYQNGNGGVAAGGLARAQHLVQQQYGAAGNASINAMQQRGGLALPGQQAKPQGLSLPAGTPQNAQQTYQQQQHVAMAHQQQQLAQQQAQPRIKVENDSPQLQQGSFNQQSSQGPNYSQTDGADEGLEEWKAMLAERRAVSAEQTRHADRMMHDHVANLSANLQSGLMVPLDQQPKRSRGKQRQGSPSTSSAASSSRLPTIPQLDGEAEEDEEKPSVKDEDDENAINSDLDDSDDEGGAGMGDDDDEEGDNILCTYDKVQRVKNKWKCTLKDGVMSVDGKEWVFHKGMGEFEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUS6</accession>
    <name>A0A9Q8UUS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767448.1">
        <property type="nucleotide sequence ID" value="XM_047911040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUS6"/>
    <dbReference type="GeneID" id="71991770"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11892"/>
    <dbReference type="OMA" id="EQFSPHR"/>
    <dbReference type="OrthoDB" id="5389296at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="37488" checksum="080FEAC8ABCE46DF" modified="2023-09-13" version="1">MPVTPSPHRFLATKRQPSPPKAATPSTSRRQAHSDRAAPGSARTPRYHRPSAAPAQFAHTPRFGVAKAGRATPSRQHSPPLSSRAQALRAALQPGEGIEEAAEHDAQDDEMLDNEQVETVPTTELAHQPAVEQAWTSNLTCSPKRRRLDDHGLGDGFDIATASPARPTFKHPTTPASALAARSQHFSRAGSVASSIGDDKTSIRRPAFLSSSVQPQERHEPLPEAFSPHRRGEKFVPGGMAATMQQWVIETGQSAFHSRKGQGYLRGEDYVLRVKVQSVRGGSPLLVEARQSDGTMDKLLLVVDAKNESIEVEKGSVVGIRAPTWDVELDGQSWTIGVDWKLLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV60</accession>
    <name>A0A9Q8UV60_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosinase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767941.1">
        <property type="nucleotide sequence ID" value="XM_047912094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV60"/>
    <dbReference type="GeneID" id="71992824"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12946"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="2">
        <location>
            <begin position="54"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="22993" checksum="2618CC85DA0AFC7B" modified="2023-09-13" version="1">MCRSAVCEWQCTDARNPGPTCLPPHEKHSSTQYDVFAAYPHTHLPPPDAPGVRTRWDEFVYVHAIDTIPDANSIHGSPLLLTFHRAFNAEMQFALRDECGCEGGLPYMDWTKYPGTPMSSWPMFDGSATSLGSNGDTTQHGCRCVTTGPISDWAVNLGSAGEDSICSQNSDPNGMAHNSHCLERLFASSPQKTSPTSAKKSSSRQSLTTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4P1</accession>
    <name>A0A9Q8L4P1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755117.1">
        <property type="nucleotide sequence ID" value="XM_047900260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4P1"/>
    <dbReference type="GeneID" id="71980990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01112"/>
    <dbReference type="OrthoDB" id="5430812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO10751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="66385" checksum="32EE33DFAE6A9D5E" modified="2023-09-13" version="1" fragment="single">MPMQYPTTKMTSEDGQQARGAQDAYNYYLAVGDAAVHKSFSSLDNPSNLEQLMGDVQHHASENFVVDFSDNAAWAGFNLSTDSLQSLFELGRPEALSTRWINIWHPFQHRSILSLLGKRYDFSPRLFALMSSDPKLPRLSASRSTMSPPARRHYWSSRSSTAEDKEAEAAELDEISEHMSVSSVDSVTHGNLYKIADSIWHYSSVDFGRQYVCVGFNSLYGTKQPHCEDEVDSKSYLPQCTRVWTWLILCEDNTVVSINEDPFPFTCPDGNYSTFQLRILAETRRNLVNVFRSLSTIHNDPLLAHNPLTLLPIRTRLGNTPEETAHRDSDAPGLLFYYLFENWHNSYTLVSRKESRYGVELSQLRSEMFQRPKLVHIDRLDKIGKELGVLKKHYSSYDRIIDRLLEPQTASAASLHNSQVVTSSSQASLDTVRPIVTEKDSLMGVSLSSAARVRFKRLRDVIDLYALSEVEEYIKQKESLVAMNFNLIAIKQSVDVDRLTRVTLLLTKATILFLPVSLMTGYFSMQLVGVEYSVQTYWLSFVICFFLSWLALFLFGLFNGTVQTVEVIKQMWRGMKRVGKTVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L552</accession>
    <name>A0A9Q8L552_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5">5.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phosphomannose isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_00867</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755280.1">
        <property type="nucleotide sequence ID" value="XM_047900015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L552"/>
    <dbReference type="GeneID" id="71980745"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00867"/>
    <dbReference type="OMA" id="QHYSEMW"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046456">
        <property type="entry name" value="PMI_typeI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF4">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="15">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I C-terminal" evidence="14">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO10914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="421" mass="46265" checksum="5F82206C7C6D7D09" modified="2023-09-13" version="1">MASVEPVYRIRCSCNQYPWGKTGKESIAARLCEGQGGWDGDGPKQTFKIDDSKPYAEMWMGTYPELPSYVADTGEDLQALIDRNPKELLGEEVMQKFGHSNLPYLPKVLSIAKALPLQLHPNKEKAAELHKKKPDAFTDPNHKPEIALALGKFEAFCGFKPLEDMKSLLELEPLQQFLSGDQLSNFTDKQLKTVVRNMLTADDATIKKTYSALTSLDKSRYGKQSHIPELAPRLAEQYSEADPGVLVALITMNYLVLQKGDSIYIPADGIHAYLAGDIIECMARSNNVLNTGFCPTSERSNVDLFMDCLAFTPHAAEDAILKPQQYKRSRNGHTQLYSPPMSEFDMLQTEIGPGQDEVLGPAGGASILIASQGNGHLRAQGKEYELAEGSVYFIAQGVGFELASKGGQLLVHTAFVEGSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5M5</accession>
    <name>A0A9Q8L5M5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Free methionine-R-sulfoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the free Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755668.1">
        <property type="nucleotide sequence ID" value="XM_047900195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5M5"/>
    <dbReference type="GeneID" id="71980925"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01047"/>
    <dbReference type="OrthoDB" id="15735at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033745">
        <property type="term" value="F:L-methionine-(R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000048">
        <property type="entry name" value="Free methionine-R-sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF15">
        <property type="entry name" value="FREE METHIONINE-R-SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="64"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="18746" checksum="1E5B28A3271DDF8C" modified="2023-09-13" version="1">MVHADSSNFEAGVSKTAAYDQIIEQAEALFDCQRNWVSNTANAASLLWHCYHALPSPSNKVNWAGFYVADRATDQQLILGPFQGKVACQTIQFGKGVCGAAAASRTTQLVPDVEKFPGHIACDGDSKSEIVVPIVVKDKVAIIDIDCAIESGFDEEDRAKLEKLAAVLADACDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L650</accession>
    <name>A0A9Q8L650_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755890.1">
        <property type="nucleotide sequence ID" value="XM_047900171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L650"/>
    <dbReference type="GeneID" id="71980901"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01023"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="69" mass="7783" checksum="9B666A793DC2458A" modified="2023-09-13" version="1">MSLLAKSLVQARAVHGKSGVEDTDDTYRTPRSDRFATGRSVNSSFINSQISEWARKKPEREGLVVVWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Q2</accession>
    <name>A0A9Q8L6Q2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Repressor of filamentous growth 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756183.1">
        <property type="nucleotide sequence ID" value="XM_047900466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Q2"/>
    <dbReference type="GeneID" id="71981196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01318"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000041">
        <property type="entry name" value="HMG box family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF320">
        <property type="entry name" value="BOX TRANSCRIPTIONAL REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="153"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="153"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="560"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="765" mass="83074" checksum="77D878F8186886DD" modified="2023-09-13" version="1">MSTAHQPSLPSLPAHWTSPHTGIQTQPANEPARIVFTRQLWQRTMPDGSRSDQVVLNRFHPQEKSDGTVVAASSSRRTSSASSRRRSPSPLRAKTPLTPEESPPCRTTRKRTAGIVEEEDKDADLIEPTSAHTRQSSGDSAAHVCICQPDPKIPRPRNAFILYRQHHQANVISQNPGLANPEISKIIGEQWQNQPPEVKNKWKALAEEEKIRHQQQYPTYRYQPKRSGRRNSLSSDGLANAEKPRCTKCGGRSILAPSTPYSLQSSGLSPASSQHTPASAITPVSRTLPVLRDLSLQSPAARRMVKQCPGSNMSPSHHGHPDERDELGPLSPDAKRRRFNGDHPSSMARPMPPRYVVAPPPGPAVGPGTPFPFGQQQPHPYPPGAVHARRESLPGIRGVVSQPGTMAPPPRPGPGYQQHRLSQGHITHDRSLTLPPLQTGNSGGIAVALATPALGKSAKDQIMTMDFSRKVAILRRVAPPGIIKKSAPRGPFVAIEGDTPEAVKDLGTWLSDTLRKDDDLGISLLEGPKLSTGGTKESLMSQYHRLVADWLTKSGEIRESLSSKVGSPTDSVMVDAVPTPASKPKGREIDEDYDDTDSSSPKERVVAGADGEYHGRESRKTSDPSAMDVSTPVKTTTDGSNRDTTATGKPVSIIANYSLHASNFFACHIPIGSNDPYSAVDHWQWTASQWRGIIGPDLTIYIRDAAAGDMGKQSVDIIEEGNLFVVKRTKAEGKETSEIEASTLRRLGFEVSEWVRAFGANAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L741</accession>
    <name>A0A9Q8L741_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756492.1">
        <property type="nucleotide sequence ID" value="XM_047899689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L741"/>
    <dbReference type="GeneID" id="71980419"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00541"/>
    <dbReference type="OMA" id="AGTECKE"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040319379" evidence="2">
        <location>
            <begin position="26"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="614" mass="65050" checksum="E8E9F6EFB43DE149" modified="2023-09-13" version="1">MTPKRQPTSGLAFCALLLSARHVLGHMEMSWPYALHSKFDPMNKYDEIDYSMTSPLMDDGSNFPCKGYQNDRPIRTVATYSAGSTYNITLAGSATHGGGSCQISMSYDNGATFSVIKSMIGGCPLETTYDFTVPSYAPTGNALLAWTWQNKQGNREYYMNCAEVEVVAGSTHRRRRRQAYNSFDSLPYIWKANLPGVSDCVTTEGDDPVYPNPGPDVVYGDGYSSSSPLSPGTCDSAKPYGETYQDLGDSPAAPAPSSNTTTPSTTDPADYGTNATTSALALDESYTELAAPASATHAPDDSYGGNDGSASNENLPDDSYTERRSATSTATMQARTLSPQAVMAPTSLAQYPPQRIMLPSSEGVSTTTVYVDCDSTVTITVTPSATTSHPATYITSVPEAACTGTAALCPCATGYGCELVGTCLWQCVAQSMPPSPPSPTPPPTSRMVTSTRAQPPPTPEPSTPAPEPQDPDPVPSNPNRPPYATGDLSVYLPCVPGTFICTSETTWQTCNYNSAADWVYGYSRTVAAGMMCLPYLSPYSNTTDEYGQQANVESGSYRDDRIVRARPDGDCDVDGSLQCTDGGTQFLVCDHGGWVRMGAVAAGTTCTGGTIVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L752</accession>
    <name>A0A9Q8L752_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein YmL11, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756507.1">
        <property type="nucleotide sequence ID" value="XM_047899634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L752"/>
    <dbReference type="GeneID" id="71980364"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00486"/>
    <dbReference type="OMA" id="YKPPEFR"/>
    <dbReference type="OrthoDB" id="360689at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="37932" checksum="35381F947120F91B" modified="2023-09-13" version="1">MPPRIRARLQANQLRPAAPRTHYVCWQCRHASVATATTPAPSIDQTLQAAPPIARYPPTQPPSYKPPEFRKSQLHRQYQSVLRSSPLMLIFQHNNLKSTEWAGIRRELATAMGKVDEELAKNGNAEYIGRDTRIAVVQTGIFASALKVVEFWDPNFEPEPPGTEPTDALTATSANLQKMKPERLLRHGLSKAAHTAVKKRKHARHGLEPLLSGPLAVLTLPSVSPQHLKAALSILSPSKEFPAPKRKANPSYHEPAVQNGLLKLMLLGARVEGKAFDADGAKWVGSIAGGLEGLRGQLVAMLSGVGAGITTTLEAASKSLYLTIEGRRTMLEEEEKPKEEKPKDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7A5</accession>
    <name>A0A9Q8L7A5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="10">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="10">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MEF1</name>
        <name evidence="12" type="ORF">CLAFUR5_02242</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7A5"/>
    <dbReference type="OMA" id="GQFAKVQ"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04097">
        <property type="entry name" value="mtEFG1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04091">
        <property type="entry name" value="mtEFG1_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000022">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000015">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000558">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="91"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="100"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="235"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="797" mass="88152" checksum="00B7546279D3470E" modified="2023-09-13" version="1">MRVTGLARSQLRNVALRSCNTASRRTFASSVLPTIRAQNHDRIAPRLQQWQSRRWASAAAAIQETAAHDPTSLSQDAIIENLDPVEAARLDKVRNIGIAAHIDSGKTTATERVLFYTGRIKDIHEVRGRDAVGAKMDSMDLEREKGITIQSAATFCDWIKKTPDPVTGELKDAKYHINLIDTPGHIDFTIEVERALRVLDGACMILCAVSGVQSQTVTVDRQMKRYNVPRISFVNKMDRAGANPWKAVDGINQKLKIAAAAVQVPIGVEDGFKGVVDLIRMKAIYSEGYKGETVREDEVPADVEAFAKEKRQTMIETLADVDEDMADIVLDEREPSVDEIKGAIRRATIGLKFTPVLMGSALADKSVQPMLDAVVDYLPNPSEVENLALDRKRDEAQVKLVSYNSLPFVGLAFKLEESNFGQLTYIRVYQGSLRKGQNVYNARTGQKVKIPRIVRMHSNEMEEVSEIGAGEICAVFGVDCASGDTFADGGLGYSMTSMFVPDPVISLSIKPKNTKDTANFSKAISRFQREDPTFRVHVDIESGESIISGMGELHLDIYVERMKREYKVEVVTGQPQVAYRETIQNHVTFDHLLKKQTGGSGDYARVVGYLEPTGNLGDNKFEQRIIGGTISEKYLFACDKGFQESCRSGPLLGHRVLGTSMVIEDGATHMTDSSELAFKNATQQAFRMAFQKAAPQVLEPLMKTVITAPNEFQGNIVGLLNKRNATINDTEIGPDEFTLTADCSLNSMFGFSSQLRAASQGKGEFSMEFSHYSPAPPQLQKELVAKYEKERAEKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L851</accession>
    <name>A0A9Q8L851_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757031.1">
        <property type="nucleotide sequence ID" value="XM_047900163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L851"/>
    <dbReference type="GeneID" id="71980893"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01015"/>
    <dbReference type="OrthoDB" id="10490835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="51498" checksum="3D9F853368313D85" modified="2023-09-13" version="1">MAATDPAAMMAAMAARILGKGSAPPLTAPTQDQAAPRTVPRQPVPAAPPAPVPTNLAPPPTPAFAGVAPASAEPSPPTVKEVGVAPDAGPSLFGTPEQLAEARRFSREATTGGNKSRPGSRSSAFPSRPSSVTSDSSRSSFARKSYTHGGANTSAASFHLTPPPVSTHATRSLAASGSSFASNGALAPPTQPQAKPDVSFSKPNTFGSTTQSLSVDALGSSAIASPKVEKAVEPKPTTPAISKPSVTTLPASAAAAPYLRAKGWQTFTVDGAGTDKDMNAEKIETKKGDVGKPMIPTVKVEPAEPAALGPRVKQESEESDYIVIPKLPAATIEKSNAPPATAPAQAQSITVSVADFDRMMAEITSLTKQVATLTQRVGSLENENFQLQGKVEPMCQLQELRQYLGTKDAKAPFELSVKCPPGTYCKVQANATLKVADLIRRVRVASKTCPAESPAPRLAVEGKELGHALTLHEVGITSNSLVEFVHDGVMAEEDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8B0</accession>
    <name>A0A9Q8L8B0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756389.1">
        <property type="nucleotide sequence ID" value="XM_047899440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8B0"/>
    <dbReference type="GeneID" id="71980170"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00292"/>
    <dbReference type="OMA" id="MGIKGAI"/>
    <dbReference type="OrthoDB" id="5407645at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="648" mass="70265" checksum="4F9D2BCF9F14609B" modified="2023-09-13" version="1">MSTYHGYDDDYDEPRRYRNVRTRPRERDEPDYVREETYIERGKGPGPRHGELVYRGREDSVEDIPRDFPPPGRSGGSRYSAYDDRRGKSVGGGRSRYSDDYDDDRYTDYAAPAAAGAAGYAAGRRDRSRHRGHRDDRDYDSEYSDSPPPRRKEPERKKSGIGETLESLGLGGLVGGLVGGANKKDGSRAGSRGGRSRSRAGSRRGGYDSDDSRSRSRGPDGKKRTERKWAQAAQAALVAGAVEAFRSRKEPGPWSGDKGKRIATAALGAGGIDGMIGRDPDKKTKRHLAEAVVGGLAASRLANGARSNSRGRGGLDSRSVSPDSRAPRSRSRSIIDRFRGRSQSRGRPGEEGGGGAGNALKGLVGAGAVAAAGKAIYDRVRSKSRKRRSPSNSSADSYVPSRTRQRDRRRSPNSDTGNTRRTDEASGREVARGTRSNAGAAAGAGAAASALTTRGNGGGNDKFNDNHVSSDSSSTTDMEKTRKHMRGKELITAGLATVATIHAAHGVYSSMEAHEKRHRLVAEGEMSPEEARKKQTKAWIQDAAAVGIAALGIKGAFSEWKEMNEQRREIQELEKRKAARRKKRIARQKQEERERHERMMSILEKNPGLAMGYKMNQEGFALPGAGAPPPPELSGNPYAGQNGGSQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9M2</accession>
    <name>A0A9Q8L9M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757842.1">
        <property type="nucleotide sequence ID" value="XM_047902893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9M2"/>
    <dbReference type="GeneID" id="71983623"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03745"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="284" mass="31817" checksum="6CE2F35B85E74041" modified="2023-09-13" version="1">MSGRVGNTGSSETDAPGAKSSKTTKQRKTRAASNGAAVASSSSNSMTTPSNDRRTTRSISRQNGAESTNRTDRIPKAQDIVARATAAEDHEDLRRTLASKSLQRKAESQETTEQPAKKIAKADHEPGNDSPPQQSSPEKRSKQPKDPHICCKCIDRLRLELARAKDAFHDTEDQIANLNAEAEQYEHSIAQKDDYIQRLLQRLENTKRPVLCTAEDDHIETLDVANQRLVARDKEWRRMFEERTLFGMVRPVDAGLRGEYEELGRRLRVAEERVRVLERGDVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9U8</accession>
    <name>A0A9Q8L9U8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71983211"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03333"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="240"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="596" mass="68651" checksum="D714C00584012E70" modified="2023-09-13" version="1">MRLRKDVNRWCCHIWDFNRVSTYGEEENDEEQALQQKHDSAIDYFHDLLCDLKDFETKEATANYFASQSDMAYNALFAEVCGLVEAYLASLHLKDDTKIYTAHTEDDLHQIFKQVSRPCQTLRKKDRQPSPWPLVRKVEVHQRANLLDSGVVLADTPGINDTNLAVVENTKRYLRLAGTIMIFLHYKRVKANTVLYEMLQECVALGKMHNIKLIITHIDEMKPLSVDEREDYETAELKSLVELEARQKKVDKEIKDTKHAKQKAKKAKDSRYPEFVDRLEELEVEKARAKAAVTQASIMIRCERIGKGVADSIKDIEKSRYAPKLPVYFISNTQYQKHVDGYDLKEPPALDVEATGIPRLRRLLYSVPAQGKLTALRTIYDHRLKGILNGMTGILTKSKLERKSEVLMVLNDGLGKPDLLVKDLCMEVKDAFKENILDVIKEEEDEWKEAAEKLVCTVWVNFNTTTLKGVFTRGEEWDAHKVHGRINLHLDLLKIYQKQLTAAFNELDGAIEVIDKEFLFKTEEMFASIQVNIEKNPDAQGQDLAAFFEFIRNVKDDISEDIRHEVQKLRASISDIRHAATINSEVSYTKKEMEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAJ6</accession>
    <name>A0A9Q8LAJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758307.1">
        <property type="nucleotide sequence ID" value="XM_047901887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAJ6"/>
    <dbReference type="GeneID" id="71982617"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02739"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="96" mass="10954" checksum="3E31B172CB589792" modified="2023-09-13" version="1">MSDNHPDHLLLGGIVLGDIIEVTAVYRFDASEADTSAWFTAAEDLITRHNVASDQFARTLLADTTYLDQRSSEDDWALRKDFLRLLEAERLPSRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB38</accession>
    <name>A0A9Q8LB38_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758476.1">
        <property type="nucleotide sequence ID" value="XM_047901996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB38"/>
    <dbReference type="GeneID" id="71982726"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02848"/>
    <dbReference type="OMA" id="YMVKFDD"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000002">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="25766" checksum="F568B30C1F000F08" modified="2023-09-13" version="1">MPGMSNPPPPSTAPTKEPTFTPIHAAKPFQSTLRYPSSRKTIYDRNLNRTKATETSLASFSYLFNTLITYHHSKSGSVSEIETRLNRAAYPIGIKLLDLLLYRQSPRSAQRPTRILDLLQFVHGTLWRALFNRPADALEQSNSKKNEYMIVDNEPIVNTYISIPKEMSQLNCAAFVAGIIEGICDAAGFSTEGVSAHWSEGDEMWPGKTIFLLRFKEGVVERDEAIKASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBM5</accession>
    <name>A0A9Q8LBM5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758144.1">
        <property type="nucleotide sequence ID" value="XM_047902303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBM5"/>
    <dbReference type="GeneID" id="71983033"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03155"/>
    <dbReference type="OrthoDB" id="3945550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040139428" evidence="1">
        <location>
            <begin position="25"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="646" mass="72842" checksum="C3C15F71A5642F3C" modified="2023-09-13" version="1">MAVTDRRVTGFLFLALCIFSTCAATNHLVLDYNSPESAREAGRVLDLIIAGDASDAIRTDNRTWILQGYASLLNRTQLDHAIRTAPETLSKLYYQLNVPIKTSTLQALDETQAGYRLYYDIPFSYWDFYDKHVPDVQSAGSEPFHSESGQQRQHILQYCSDLYSVTAHMNYGSDANFDDMPFLYDILTNCPGVRELDLAITHSGCVVSHYESAFDFAESKKMFAPLESLKLSGYDLHYTPAGERRYGAREFQRGSTPNTFKKLASTVRLLASSLHRLGIRDGLRDFYNFMMSFSSYPYETRSVPGPEVAYDNLDVWLQRMDWSRLRHLDLGHVDMDKLKTVVASGASPESLVLHRSHCCSPEEEYSDLVRSLTNPLKHLKVKDVAFEAYDELIDALSPTGDNLESLTVTEGEYNRDEYCSSRPSEEHCLETFGTYYLPRPFLNASQLHQISQQNANISALEVDIARIVPDIEDRSTWSLDHAALKAAAMLPQLTHLKVNIEPPDHLLVRAGRASEYPGLRRQSDSKQLPPFSHDPSLNRTSVPALFESVNGNRQKAGLVSLGRLDLNVGQWSQRFSDWGMLGPPGLMIGDWVCEAVDGGELSWCYGGNDHLDYADIEDPYSEDWSVPDPVRVCGWGSEDFYDHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDA8</accession>
    <name>A0A9Q8LDA8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758954.1">
        <property type="nucleotide sequence ID" value="XM_047902297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDA8"/>
    <dbReference type="GeneID" id="71983027"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03149"/>
    <dbReference type="OMA" id="FMCASFA"/>
    <dbReference type="OrthoDB" id="5427833at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040405145" evidence="3">
        <location>
            <begin position="20"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="23055" checksum="CC2072FB02973A65" modified="2023-09-13" version="1">MRYHTSTFALLALPATVLAVSLADFKPRVSDLPSKCQTVYTETIDGCSPTDFTASTCSTGCVKALQALVADVKSACGNEDISGENVIAAFLNNAGPQGLCTNANAVLGSGSTTTSPASSSKPSPSSSATPTSSRQASSTSSEVTTSTAASSTKTATSLESATSTPSSSIATDPSSSPTATPTQAASHSSSNGNSGGGSPFDTEGNMHSAATAIENTVAMMLLAVLVALAGALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDF7</accession>
    <name>A0A9Q8LDF7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein alcS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759715.1">
        <property type="nucleotide sequence ID" value="XM_047907841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDF7"/>
    <dbReference type="GeneID" id="71988571"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08693"/>
    <dbReference type="OMA" id="PPNKVKG"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33295" checksum="37C802EEB2DCE3B6" modified="2023-09-13" version="1">MSDTYNATQNNANLTAPGAQGNGPLEKDYGNGYHLDNNMDADTALRKIQTSGSISISPELFEKIYLSPQNKVAGDLRKTFGNPTPLCLVGFLLCLSPLSCDLMGWRGAGGNGAASTGVFFFFGGLLMILGAVGEFILGNTFPFVVFASFGAFWLSFAATLQPFYNAYGAYVTEPGAPVASGLETRGFNASFAFFLVFMGVLCFLYMILALRTNLIFFLIFLLLVPSFSLLAAAFWSLADDPVARASEAQTYVITAGALTFVIDMLGWYIFFAILLASLDFPFQLPVVDLSRFVKGASYKKKREEYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDK7</accession>
    <name>A0A9Q8LDK7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-galactonate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759630.1">
        <property type="nucleotide sequence ID" value="XM_047907595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDK7"/>
    <dbReference type="GeneID" id="71988325"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08447"/>
    <dbReference type="OrthoDB" id="14161at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050023">
        <property type="term" value="F:L-fuconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03324">
        <property type="entry name" value="rTSbeta_L-fuconate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000007">
        <property type="entry name" value="Mitochondrial enolase superfamily member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034610">
        <property type="entry name" value="L-fuconate_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00111">
        <property type="entry name" value="L-fuconate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00270">
        <property type="entry name" value="L-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="5">
        <location>
            <begin position="198"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="50376" checksum="C85F9777ACCB1790" modified="2023-09-13" version="1">MVTITGVTTRDVRFPTSLDKTGSDAMNAAGDYSAAYCILRTDSDHEGHGMTFTIGRGNELVCQAIALLGERVKGRTLESFVEDWGKTWRYLVSDSHLRWIGPEKGVIHLALGALVNGIWDLWAKVLDKPVWRIVADMTPEEVVKCIDFRYITDAITPEEAVQLLKEQEPTKAQRRQEALEHRAVPAYTTSAGWLGYGEDKMKSLLQETVSQGYRHFKLKVGTSLEQDKQRLRTARDVIGYDKDNVLMVDANQVWSVPEAIEYMKELAEFKPWFIEEPTSPDDVFGHKAIRDALKPLNIGVATGEMCQNRVIFKQLIQQGAIDVCQIDACRMGGVNEVLAVLLIARKYGVPIVPHSGGVGLPEYTQHLSTIDYVVVSGKLSVLEYVDHLHEHFLHPAVIKDGYYTTPMNAGYSVEMKSDSMDRYEFPGKEGVSWWKSEEARPILEAERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEA9</accession>
    <name>A0A9Q8LEA9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760271.1">
        <property type="nucleotide sequence ID" value="XM_047903784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEA9"/>
    <dbReference type="GeneID" id="71984514"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04636"/>
    <dbReference type="OrthoDB" id="3824970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="250"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="531" mass="60710" checksum="3D51DDF8267EC5DE" modified="2023-09-13" version="1">MAAGPIDPTEIPERPAGVFEPHHSITLLYPSFTLIKPGERATITMPLGARARYEPHPIVPVESVIANKTSRNETIGTDFTVYLPVSDVGSHDMELSGELYHDMQQVTARVGHTKLRLMLVTKDARMDNLDDATIRISRFTKSVVQGGKARYTKSQYEMSCGDFIQRSTITQRLWDACALELIMQSSDRAVKHQRLRLAIHDITEPENDEWRSPRGIEMDDAIPKIANIMSKAELDQFNGDLADDERIDQCPVCLDDFSDTDSPVKLPCSKKHIVCMSCLREWCKVGGVHKTKCPWCAVQLATPEAIECLRPNYLDMKAVYEVDIRYNRYENHERRCADLDQYHAQDNSTTITINNNRLLETWHHLVELQPKSEPGYSHLNQNPVDSPEYVDVLTAFVTFCDTRRGSSITIQDAFHQSREAIFTALRAKLRISGMYDFMPMERKDSIDRDVYKVPLRPGFKEWIQCSLNRVLQFQTIRQCKTKEECAGMISSHMHGGCGGREYFTSKWCSTEDPVGRYRAKEILRWCVPQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEM8</accession>
    <name>A0A9Q8LEM8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA-binding protein 8A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
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    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO15987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LES6</accession>
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                <person name="Stergiopoulos I."/>
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        <location>
            <begin position="496"/>
            <end position="518"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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                <person name="Samaras A."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF01"/>
    <dbReference type="GeneID" id="71987810"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO15473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10982" checksum="FACF1EA799E3027E" modified="2023-09-13" version="1">MREQLRSLLDILDSVTVVRMSYWSKLDELDDPLDAHREAVTEVYKAHLDSVDQLKKLKVESCVKMEEPEGYRRTWKWVGKENNDIIDEDDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFB1</accession>
    <name>A0A9Q8LFB1_PASFU</name>
    <protein>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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    <dbReference type="GeneID" id="71984037"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="223" mass="25256" checksum="1E8D71A977B3B19A" modified="2023-09-13" version="1">MALPAPPLPGDGAFFIDFEVEMMGWTRGLKYSMNDLALFQRALRQRTDDGPRAYQHNQDLAQHGDGVAREMCRAQWREAGDSKRDFHDFYEGRASTEEFLSYVADSQELSLYILRAGNGPSTFTNHEKADVVEASIGAVDQDCNGAVDVMKEVLRGFGICYPMTDEEVDEMERVWELARRALAEQTAAVLEARRAAEAEAKAKAAYEAWRLWCWQQYWAQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFJ3</accession>
    <name>A0A9Q8LFJ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="10">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO16467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFJ3"/>
    <dbReference type="GeneID" id="71984897"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05019"/>
    <dbReference type="OMA" id="RYIRHAR"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040259402" description="J domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="45"/>
            <end position="145"/>
        </location>
    </feature>
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            <begin position="220"/>
            <end position="283"/>
        </location>
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        <location>
            <begin position="387"/>
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        </location>
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        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
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        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16467.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="408" mass="45714" checksum="5A2F26E1FBE862C1" modified="2023-09-13" version="1">MRDFARVAVVLLTCIVALAAAWTKEDHEIFRLRDEVIASEGHNVTFYSFLGIKPNAGQDDINKAYRKLSRTLHPDKARSTWIANYNKPKVGKKGDTPKVHVTKNKQPSQSEIKKFDKEASARFERLSLVTNVLRGPERARYDHFVYNGFPAWRGTGYYYERFRPGLGSVLFGLFIFVGGGVHYGFLYLTWKRQREFVQRYIGYARKKAWGDEGGIGAIPGLGGATNGAPTPQSPPDADDSMQWNRKQKREMERQRKKDGKNPVKSARAAAKAREQGISTPVEAEITSGPVGAKKRTVAENGKVLIVDSVGNVFLEEETEEGDLQEFLLDPDEIPAPTISNTWLVRLPLYLYNQSLGRALNKQTPEQIVYEVVQGQEQEEVDEATAALNSALPPNANGESRKRKSKARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFK5</accession>
    <name>A0A9Q8LFK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein</fullName>
        </recommendedName>
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        <name evidence="7" type="ORF">CLAFUR5_04941</name>
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    <organism evidence="7 8">
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71984819"/>
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    <dbReference type="OrthoDB" id="19344at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </feature>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27931" checksum="6EFFE6A5FB0204BE" modified="2023-09-13" version="1">MHVYYAEEEADAEIKGRRPSISGPDRTFRRARRAWIVLLITCAFAFAVLLVCAIVLHRFPWVAQTWADILGIAVTILAAIQWIPQVYTTWHLGHLGGLSLVGLILQVPYTWLFAVNMMVRVGWTGWSAWIVYVLVGLMKLVLIGFGVVYAYRDRGKTPEDKDRRPSVSPSEVHDRFSIWKSFSQRGRTPSNNSRATRFSNVAPDEHHRAPSNTSRVHRFSNITIDERRPLLSDARSPGREQAIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGE0</accession>
    <name>A0A9Q8LGE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AB hydrolase superfamily protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04339</name>
    </gene>
    <organism evidence="3 4">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71984217"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_3"/>
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    </dbReference>
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        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="98"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="342" mass="37927" checksum="94178A0508771BB4" modified="2023-09-13" version="1">MPFILNDPKTWPTTAKSDPEYDAAIKAIGGAPDMGKFPSIAAMRQFIEDNKANMVATHEPIPNVKEEDRHITMRDGQQIAVRIHGPEKPAAGRSPLGVVYHGGGWCIGGLINEELLCRLMVSKYNMVVVNVDYRLGPEHKFPTGHHDCYDATKWAAENASSLGADPSKGFIIGGTSAGGNITAAVSHLWRDEGLTPKITGCHLMIPMVCADSFHPKDKDLASWGQLEFAPILSHAACKLFLDNYIPNIEDRGNQLFSPYLWKTGHKDLPAQYFQICGMDPLRDEALLYERHLREKEGTKTKVDMYEGVPHGFWSLFPQLEGSKKFVKESVDGVGWLLEQGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGR1</accession>
    <name>A0A9Q8LGR1_PASFU</name>
    <protein>
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            <fullName evidence="6">RNA exonuclease 4</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        </citation>
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    </evidence>
    <sequence length="155" mass="17564" checksum="ECED536BAF564DB6" modified="2023-09-13" version="1">MNVRHHLHTHSTTIIHGDEIANHIEIIVRSVADATNSRIFDQDQSPWDDFSPLFEAFIGDVNVKRSNLTHFIAHLRKMCTTHPEFYFQVTSLNVNVSPKKQIAEVFLNMDFEGMPPGIVRPAVATISFRLVGEKWLCTKWTSLRGLVDGVEPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH14</accession>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
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        </source>
    </evidence>
    <sequence length="443" mass="49946" checksum="FDDFAC1E52A53890" modified="2023-09-13" version="1">MCLVLAQRSMSVFSPTNLPGQNIIQTRNTINKPGALLDFMSQILPSDIPPQRPTSGIDEYPDIHTPEDLLAKVEEGIKIAPMPVRLSPHILSTINWQDPLNDPVRRQFIPMKSTINVTHPAASLDPVAEVNSSPVEGLIHRYPTKALFMTTSVCPVYCRFCFRSYTVGTETETVKKLRFLPLLKRWKPRLEYIANTPHLRDIVLSGGDTYLLEPEQVEWLGKELLKIPHIRILRFATKGVGVSPSRLVDPDDAWTKVIIDLAQEARKMSKHVCVHTHINSTQEITWVTRRGAKRLYEEGVTVRNQSVLLNGVNNTVPAMMNLIHALSDMHIEPYYVYQSDMIPGAEDLRTPIRESHHIESEIRNQNAGFLMPRFVYDVPASGKRPTLFAHYADEGLGLSKFRLPEAHGGSAEYWDPLWSLTEEKRVVIGERFGVGVQGVRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHH9</accession>
    <name>A0A9Q8LHH9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoamyl acetate-hydrolyzing esterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761868.1">
        <property type="nucleotide sequence ID" value="XM_047905629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHH9"/>
    <dbReference type="GeneID" id="71986359"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06481"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="30208" checksum="2B36672F35B75AE2" modified="2023-09-13" version="1">MVQQHFNMDQFVLFGDSITQHSFSQERGFAFGAELCNSYVRRLDVVNRGFSGYNTRQALQVLPHALPDPKCARMRFLTFFFGANDARLPETPGGPQQHIPLEVYKENTIAMITHRNVSAHEDVRLILITPPAVDERKCLENDQRNNPDFPDVIRRKASVTATYAEAIRDIGSQYDVQVLDLWTAMIIRAGGNPADTEPVGSIDVPCNEILQSFVHDGLHLSPTGYEILYDEMMALISERWPDQMPDKLSFVLPAWDNPEAWHAHGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN6</accession>
    <name>A0A9Q8LHN6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761715.1">
        <property type="nucleotide sequence ID" value="XM_047905208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN6"/>
    <dbReference type="GeneID" id="71985938"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06060"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040232193" evidence="2">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="12686" checksum="9F47A7E28B021519" modified="2023-09-13" version="1">MLSNTMLLQQIFITLYAAAAGIALAAPVQPDAMGRFEPRDVSPALDGGPSVGLEDMAINIRSDLWKRPVPGRPRSIGGRDALPAFDAGASGELADAVAERRSDLWNRPVPGKKPPKRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIC8</accession>
    <name>A0A9Q8LIC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761519.1">
        <property type="nucleotide sequence ID" value="XM_047903807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIC8"/>
    <dbReference type="GeneID" id="71984537"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04659"/>
    <dbReference type="OrthoDB" id="125903at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="419" mass="44971" checksum="292055A25ACD20B5" modified="2023-09-13" version="1">MAAAVIDIKAQATFPIRLGASILKPSKPSSFTSVRYNHKPRLEQANSITAKISKGDDEGESELSLKNGDGEYQYKGRHTQDENTYVLVLRGQGKDKEMLLERMNGGHNFNLVSTPAEGDAGKLAEKYPPLPLEDEEGDLFGEDDEDTPPDDSNPFDYRHFLKAELEKPEPTNVNIDAVRSPAITPLPRAQPVASTSANRGVKKAVKKPEPLKKRKTNAAEKANPKRVKAGQEPPAPATAAKPKPKAEVPNIHMDRKASVRRESVAEDDGLLVIEDETPTTEKPSKHGAMALALSGQLGSGPISLRSAANSPGGSHASSPMPARPEANEEKEQYVFEFDDDAGSEPADDEGADADEEDDDADVDEDIELPSPTQPHRPSISAAVVTGGGDDDDDLEAQLAAGLMEDDDGGAQESEESEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIW7</accession>
    <name>A0A9Q8LIW7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="4"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762686.1">
        <property type="nucleotide sequence ID" value="XM_047905618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIW7"/>
    <dbReference type="GeneID" id="71986348"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06470"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF113">
        <property type="entry name" value="POLY(A) RNA POLYMERASE CID11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="120"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="9">
        <location>
            <begin position="341"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="448"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="552"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="750"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="851"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="913"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="971"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1013"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="807"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1049"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1097" mass="120656" checksum="5B0273D99872DE03" modified="2023-09-13" version="1">MAGLPNGTNRLDLSRPAVQSQASNSVPSTPFQKPRDLSRRFSRSPSPNRGLSNQSPHSVASEAIGGNGRAHRGAPVVCKFESGEEFRKRRMPYVDGGDQELSPPKKEPKKTLNPDERDKLSGDMRELYDRLLPSQESEERRTKLVPKLDRILNDEWPGNDIRVNVFGSSGNMLSSTDSDVDICITTTLKKLDPMHSLAALLHKHGMEKIVCRAAAKVPIVKAWDPELQLAIDINVNNPLALQNTRMIRTYVQLDDRVRPLAKIIKYWTKRRILNDAAYGGTISSYTWICMIINFLQRRKPPILPSLQKIVDRRRKNESGEESTFADDIDALKGFGDANKESLGELLFQFFRHYGYEFSYSTHVISVREGRLVERKEKGWAASDFHNKESRASICVEEPFTVDRNLGNSADIYAWHGIHTEIRRAFELLEDGLQLEKCCEQYVFPKEEKPIFQKPPPKPKPTLTRSASQSGQNNREPGTGRSRKANRNQSSQRAGGRRASSGASFSNQRIGLPFSPPMGAAHGDYFQARGTLHEQLAQQYQILQAQEKALMQQLAQQQHTQTQGRKGDPAGSGSPRPRPHMNGLPSPRIMDHPPQTAPLLPGYPYHYPARYPPPSPMSQARSREGTNTNPPSPALSAAMPALRRQVHRASLPDASASSIRSQSQPGRPMQHPLALQQQIHPGYDVTGALGAHYQSIRSASQMYQPGQPGLPMPFAPYSAGPYPGVPSMEHVGPKEYVGYYVSPQLGPQYAGAGQMQPPQMTLQNPPTRQRRVTPDLMPPLVNDRHSSRSPSPLGQARSYAVPGDRRSSQPLAMSIQSPGSMTHSIPTLPPIPALPAPVLPIAPAHVDTGGPLIVNGSTSSHLPQQIPRANGSSEVDHRAYHDPAPIIQQEEAYVPRPLPLRTNLDRSAPEQMLSMERRTTSPLQSPTCGTKPDRGLMLSPNGLTPHVNGVNGHLHESTSLSAAPLLSPVAELRTPSPTRSRGFDTYESPEANGGLFKAAKIANAKQVAKEVVNENQAPHEPFKHERQGSASIMAESRPSAATKESEPKSALQTVTNQSSWQQVPKKTHRKSKSMAGSKSANGFGGQPLPANESERKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P348</accession>
    <name>A0A9Q8P348_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">CLAFUR5_00233</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P348"/>
    <dbReference type="OMA" id="AACDQTT"/>
    <dbReference type="OrthoDB" id="422364at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000027">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="98" mass="10868" checksum="699CAD2B78C97F38" modified="2023-09-13" version="1">MSLNSYLNRKVCLILVDGRCMVGNLISCDNVTNLALENCVERIIRSPDEEEPSEEEPRGLFMVRGDNVVVCGLVDEELDGSIDWTKVKGSEIGTTKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4N8</accession>
    <name>A0A9Q8P4N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">V-type proton ATPase subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757387.1">
        <property type="nucleotide sequence ID" value="XM_047900573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4N8"/>
    <dbReference type="GeneID" id="71981303"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01425"/>
    <dbReference type="OMA" id="QHMMAFI"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="233" mass="26785" checksum="B1444946554EC6BF" modified="2023-09-13" version="1">MSQIHAMSDDQVNTELRKMTAFIRQEALEKAREIHLKADEEFSIEKSKLVRSETSRIDEEYKKKFTQAGMSQQITKSTLSNKTRLRILSARQELLDKLFEDANKKLAESATKDKGKYDKVLKDLILEGLYAFVNEKKVTLRCRKKDEDAVKKAAEQAKQEYKKNMNNRDVEIDVDSKERVPEGSAGGIIILNSTGKIDITNTFEERLHLLETDALPAVRATLFGENKNRRFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P531</accession>
    <name>A0A9Q8P531_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758076.1">
        <property type="nucleotide sequence ID" value="XM_047902475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P531"/>
    <dbReference type="GeneID" id="71983205"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03327"/>
    <dbReference type="OMA" id="CFATAPQ"/>
    <dbReference type="OrthoDB" id="3888684at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF1">
        <property type="entry name" value="INHIBITOR I9 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040324396" description="Inhibitor I9 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11035" checksum="DEB9904E95E83A07" modified="2023-09-13" version="1">MKFTFNILLLLAFVVFALATKQQQPLKPYIVSYPKHTPSRFLEDAKKAVLHAGGVITHEYNSITGFACKTSKTVLESIEIMASGHKILIEEDQTISINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5J1</accession>
    <name>A0A9Q8P5J1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase DMA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02703</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758183.1">
        <property type="nucleotide sequence ID" value="XM_047901851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5J1"/>
    <dbReference type="GeneID" id="71982581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02703"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000030">
        <property type="entry name" value="FHA domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE DMA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17123">
        <property type="entry name" value="zf-RING_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="225"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="367"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="61"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="422"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="590" mass="63624" checksum="F09FCD339FAFD511" modified="2023-09-13" version="1">MVAYTLPITTHGFTSPPRMQIQSASSTASLNSSNATPASPTRPSRLRGLSYLRSYTRDHLHSYSTPRSEAPPLIRSTSSPGATSPNTSPRPQHTNTFERGSGSAIQSGENGWIPAIQGRREAAPTTSTSTDTAAPERSSMAMTRNRGPAPTPTSTAQAAASNHPALRRPSAFETASTADTSSAAAGSKDQHPVIRFIPHIETRSSRPSLRFDALSRTLKTPGSVVRVGRYSERDNNPTNADNGLPVGFKSKVVSRRHCEFWCTDGQWYIKDVKSSSGTFLNHVRLSSPGLESRPYPVNDGDIVQLGIDFKGGEEVIFRCVKIRVECNRGWQKSLNTFNTTAHKRLFKSALKAKNRDSDAGSVNSSECSICLNPVAPCQALFVAPCSHVWHFKCVRGLINSQHYPNFSCPNCRFVADLEADVEQPDEGDYETDEAEEQPDVLPAGDDIDRGTPDRDSGHGQSDDSYEHVARISSAPRLGSMSRQQEVDDDLARLVNEASLRTPSPQQEHSSDSADAGPSATSRPIRIGQPMSATRYASGPSGARSVTPTSHAPFALSAGPIVDGPMTPRNDVGPFVLNGDRLAEDGEGSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5T5</accession>
    <name>A0A9Q8P5T5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine protease Hip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758453.1">
        <property type="nucleotide sequence ID" value="XM_047902131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5T5"/>
    <dbReference type="GeneID" id="71982861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02983"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="476"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="66337" checksum="BD94277FAFF9C3B7" modified="2023-09-13" version="1">MYFPLHALLNTMITSILAISLCCSFTAAFVAEKQFVGQDQDTTSPKPETLSNFDWAGITAAEQLDYTPCYGDFECSRLIVPLDWNNASSPNNISLALIRLPAEVPESDPKHGGTIITNPGGPGGSGVQQALQLAQKLQKLLDGPKYYEILSFDPRGVFHSKPQAFCFDTIIDADVWYEQKRAAGGLDDGDYSLKYNWALEKARGTLCAEAENGKFQDGENLRNHLSTAYVARDLLEIVKKIDRRRRLNFWTANQIPLGAEFPQSSTKLQYIGTSYGTFLGQTFAAMFPAHVGRMVLDANLDPDNWTSRYEASIDDHGKIRDLFFETCFAGGSECALFREYDKSVDDVKSRYDAMIDSLYELPASITGKGRATPITPVDIYQGLFTATYQPLWYFKLFANFTNQLVTGVNPAPPFWQLPVPNREAFTDELLINQYMGGEVGPATHCSDGPDLVNESLAGYQTYLGNLTKRFGWAGAIQADYKIPCWTWPASLRTKWRFQGPWSTSVPILFVNNRLDPATPIKNARKMAAQFNGSVLLEQDGAGHGALWPASECMWSSVKSYMQHGEMPHEGTVCRALCRPFAKDDCEGIGADNYQLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P647</accession>
    <name>A0A9Q8P647_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758975.1">
        <property type="nucleotide sequence ID" value="XM_047901628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P647"/>
    <dbReference type="GeneID" id="71982358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02480"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16355" checksum="722A92A42AB20501" modified="2023-09-13" version="1">MSDQTVAAAATAIQWAYVVTRLDYDHWKDDAKEEHHLMGIFLDLQSANDAAIKHARRVRSRAFPIAGRDPGSSEQSYNSLGAVHLECRTMEDDRDHFTVEVEQYVLDVLDAGFSESEDASDDSKDGEDVSELEQQEDGPPAKKQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6J5</accession>
    <name>A0A9Q8P6J5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase bsc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759263.1">
        <property type="nucleotide sequence ID" value="XM_047906992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6J5"/>
    <dbReference type="GeneID" id="71987722"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07844"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="28915" checksum="AF6587D17F18D82B" modified="2023-09-13" version="1">MTDCKRMLDKGKEMTQNGLFQVSAGSGYKIIVPSRFADELRNNETLSFSEVTRKGFYGDPPGFDSMKEASRADNLTVDMVRTKLTQALGLVTDDIVDEATYAIDKWFGESLDWRTHRIKPTLCDVVARVSTRILAGKGLARDEEYLEIAKQNTIDTFTAAQLLHGYPGLVRPLVHWFIPQCQNLRRQAAKARSLLTPILQQRSVDGQELKRTGKVTDAFTWMEQTATGRPVNHVEGQLNMSLAAIHTATATSLLVLDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7G2</accession>
    <name>A0A9Q8P7G2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760476.1">
        <property type="nucleotide sequence ID" value="XM_047903874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7G2"/>
    <dbReference type="GeneID" id="71984604"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04726"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="38372" checksum="81D3602F283C70F4" modified="2023-09-13" version="1">MSRLLAFIGSTPTPTTSFEPTTLDFDDHSLNNTLISRDRPIGFFGPVRGRQYQLRVNAYRNDKGGCSWPDGIEAELTLPLPPPLAKNFMGGINLDMNGQCKGFNFKHKDLTEMISMSLPTRWYFPEVKHCEVAFYQQYYCEGLLMGFLTERDARATETNCFELLGAHSAKAVCGETWWDVWDQAGIPWLDPNSPWFLDDHDEWLLDVSGIVMGNKNFFKHCHPGDVECVLWAATTSKQLQIHDRDGEKRRVWFEKMQAKGQKLDFSKDQYRECDWNGRCGMMCPKGNGYRVLCDGDMRKMPKGEEYPYNQAWEIASPNLPGNTIGNQRPLGAEPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7U6</accession>
    <name>A0A9Q8P7U6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_05183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="323"/>
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            <begin position="70"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="520" mass="57066" checksum="8031BB9F70AFC834" modified="2023-09-13" version="1">MALGTPAVPVQHGLESEKANGVGAEHKQIFENVHEAAERGHVATDQYGHALVDFDPKAEARLRRKIDLYIVPTVALLYLFCFIDRANIGNARLAGLEKDLKLTGYDYNAVLSVFYISYIIFEIPCNVLCKYVGPGWFIPATSLGFGVMSVACGFVNNMAQVSGVRFLLGLFEAGMLPGIAYYMSRWYRRSELAFRLSLYIVMAPLAGAFGGLLASGILKLPHFGSLHSWRMIFGIEGIITIGISLIAFITLTDRPETARWLSAEEKELAIARIKSERVGTTAVLDKIDMKKLLSGIFNPVTLSTSFVFLLDNVTVQGLAFFAPTIVRTIYPNQTVVGQQLRTVPPYVVGAVATLVIPYLSTKTDRRSIYFVASAPLMMIGYIMFLATEVTDTQARYGATFIIAVGAFSYGALCNAQVSANVVSDTARSSAIGTNVMLGNIGGLISTWSFLPTDAPNFPIGNGLNLATSSTILLLSIALLFWMKFDNKKRHSRDVDAELAGLEQKQIEDLDWKHPAFRWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7W8</accession>
    <name>A0A9Q8P7W8_PASFU</name>
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        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_05284</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="507" mass="57361" checksum="A6E077B393965318" modified="2023-09-13" version="1">MPYVHIPGIRRPRVTAAQLEQLRRDLAMARPRRPQNLTRRIDYYANTSLDMSGPPLPQLPRRRRQPHDMQAEQQAIQNIQIMEEAHAEEVEEEHAADSADRKADRLVNWQSGTEDFKRVFETAVDNWVRTHSPAAQAFQKHLVNAAISAEKDVRIYDVASWFPNLPHDVALPLRDLCKRLHGAAKLHHSLLEKKDEAGGMLFDDQFHPELAFGMCCTKLTIQPLESGGEVITVGQYPNFGTDETHMEFVGRFDNFDNPHPQAKPLTLRLALYRIQAQLETRKVLLQQGARNQFDTTSMSTLRIAYLNPVVTKADLQPAFAAHGNVVNIYIEPPAGTGILESSTAFVRFEHPEEAAKAHLARRNTLFQGNMIKISRVTPDLDRITTWDESVDKAMCEWSLAALDYLVGKLNAFNQKKVADVEEGRLIAQVHNEVKGFCKIHNFPQIAMAEGIEGEYDETVVMDSDPASTPALRASLDALDDQLEVFEEEFGDGIVGPDWRMSYRGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7X4</accession>
    <name>A0A9Q8P7X4_PASFU</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7029" evidence="3">
        <location>
            <begin position="117"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="26323" checksum="32CC983B77E74DAA" modified="2023-09-13" version="1">MAVFGLLLQLSLHILAASQTLITITETNRACSSRGTRSTASLSTQTRDGSTSASLWNTQGGTATTIANGGPTLVPGPPPSSNGGDLEILNPGNNGIMYYCAANDLASCSRLMVQLNATFSFPTVILEHSAYISRVDWSESELSIRFNSPGAYEYVKQSWNLPEASLVPRDLITPFVLATTAQESSGAQRDYFIVNKVHYDDADLVVVCYGSDLDLDGAVDDLGIQWGSYANEANTPAPSSISGSVGGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P821</accession>
    <name>A0A9Q8P821_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_04265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        </lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P821"/>
    <dbReference type="GeneID" id="71984143"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04265"/>
    <dbReference type="OMA" id="RAVHQDY"/>
    <dbReference type="OrthoDB" id="5367448at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29149" checksum="3DC813E493C217A2" modified="2023-09-13" version="1">MSASIARSTANRALHLRITPRPSNLGESREILQLLSGFGEIEYFKNLKYDTLTHPNIALVIFKEEAAATHCSKKAPIRFRMGKAVGNDGIYDNEPALSNSNASSESQEVARPPRIKPSPPSNAPFGLSQTRSMSTASYQPTIPEPPPRAPVRPFDPPKPTMLEPRLFQIQTSTARSNFRDQINMGGYHGNFSLDNKSMAQRDLQKSVPVPGMSCVNWRPDARPWRLMQREKEQEQKAKTLWQLHKEGPEGAATFRDESLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8D3</accession>
    <name>A0A9Q8P8D3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein rhoA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761389.1">
        <property type="nucleotide sequence ID" value="XM_047903627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8D3"/>
    <dbReference type="GeneID" id="71984357"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04479"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="281" mass="31278" checksum="A45EBE69251D2484" modified="2023-09-13" version="1">MYLSPGRTASSTWEPSGQRLHGFLQWPLVKPWTLSRDDVRLVAQELIAGIHDTHTLSHCQTPSTMLPTTKLADAPVVPILFLGDSGVGKSTLLSRLSVGSDSKKPLPQLRDLDQPYVFNIKLYNRSYRFELYDTASPTSYTLLRPAVLVLCFNIGDPASLDSLHTTWKRIVEEHFNYDESLPVIVLGLQRDIRTKEDYGGQVRTMAADAESGADTAALNGRTFVYPQEGLRVAQEMRTDRYCECSALTGELCREVIEDISKTAALTTTDKGGRTEYQCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8S6</accession>
    <name>A0A9Q8P8S6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF788 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761678.1">
        <property type="nucleotide sequence ID" value="XM_047904691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8S6"/>
    <dbReference type="GeneID" id="71985421"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05543"/>
    <dbReference type="OMA" id="GRPKYDA"/>
    <dbReference type="OrthoDB" id="10012212at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19613" checksum="89AFF721C14608ED" modified="2023-09-13" version="1">MAKKALKTLAQQNAATLAKTHSISLGINILYLLLSLVVFRRRSITRYILLNFPALVIEFWFERIGRPAINEDGSVKQAGEDLEAKGLTEWMWDVLYWTWGNVVLVALAGDWAWWLMLTPVGYSGYLAFSTYTGMRKGMEGMMGGQEDAAAGGAASGGQSKRQAKMEKRGGQRVQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8X3</accession>
    <name>A0A9Q8P8X3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06059</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761914.1">
        <property type="nucleotide sequence ID" value="XM_047905207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8X3"/>
    <dbReference type="GeneID" id="71985937"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06059"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="100"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="48120" checksum="6E4737F2E44B40FE" modified="2023-09-13" version="1">MIFKPAFRRSLHIVYSSTPSAPVSIPNTSTMASGPVLEGVFAVNKPPAISSAQVIRDVQNHFNPSKLFQPWLQREQSKRDAEKHNQKNKRKWRGRRETSVKMGHGGTLDPMATGVLILGVGSGTKDLGHFSTECTKSYEAVVLFGAATDTYDTEGKVVGRKPYEHITKDMVEEALVKFRGKGMQRPPIFSALRVQGKRLYEYAREGKEVPVEIKERPVEVSELEVVEWMEGGTHKWHWPEREADTEEKKFAEKALKLEGQDELKVKDEVKAEDDVATAGAAKRKREADATGHPETGLVEPEQKRSKEEDPTTEPPAKIEEVQNAKDDGKEAQPESADTTTPAATERPPCPAPACRIRMTVTSGFYVRSLCQDLGAAVGSLGMMTDLVRTRQSNFELGTNVLWYDELKQGEDVWGPKVKKLLEEWQEHKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K6</accession>
    <name>A0A9Q8P9K6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-mRNA-splicing factor ini1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762756.1">
        <property type="nucleotide sequence ID" value="XM_047904900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K6"/>
    <dbReference type="GeneID" id="71985630"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05752"/>
    <dbReference type="OMA" id="AYYCWEC"/>
    <dbReference type="OrthoDB" id="10248186at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="108" mass="12224" checksum="BAF4214FCDA2923A" modified="2023-09-13" version="1">MSRHHPDLVMCRKTAGISIGRLCDKCDGKCPVCDSYVRPTTLVRICDECAFGNYQNKCVVCGGEGISDAFYCFECTRLEKDRDGCPKIINLGSSRTDLFYQKKNFRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9S4</accession>
    <name>A0A9Q8P9S4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762844.1">
        <property type="nucleotide sequence ID" value="XM_047906851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9S4"/>
    <dbReference type="GeneID" id="71987581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07703"/>
    <dbReference type="OMA" id="QKIVMAY"/>
    <dbReference type="OrthoDB" id="4388755at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF2">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040462570" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="39"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="27318" checksum="FBB9379C44205B2B" modified="2023-09-13" version="1">MLNPSVAFVALAAARIASAQYASTTTFTFTQPTGLPNGLASYVSFVPGGENTKYEGHEFQPELSYVEGGYLNLLVPGGQQNEAVIWSAEVQTTFTVSAARVDTYAILTDTAGVVNGMFSYDGDTSISGGVQESDIEWLSDATSATLVDQGLSRALLYTNQNTTVVGGQSTTGPGVVPADAFTNVHKYSIDWSNGQTSFFLDDVAQYGFTTNVPTTTKASWVWNCWSNGDPYFSVGPPATDAVFKIQKIVMAYNPGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA37</accession>
    <name>A0A9Q8PA37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763059.1">
        <property type="nucleotide sequence ID" value="XM_047906572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA37"/>
    <dbReference type="GeneID" id="71987302"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07424"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="33859" checksum="C8BC21ED3883AD27" modified="2023-09-13" version="1">MRGSEDFNLPNYNDMCRDALEQIDLSVRMIKSYPKDFQFIFGPEEVRSTYQSDKIACSIGLKGLHQAGNSISVIRAYHQLGVRYCTMTHVENNAFADASTSKSVEISDPETGMMVDLSHVSEDAAKQALSCTVAPVIFSHSNARALFDCPRNVPDTVLDLVPGNGGILMVTFVPEHLCTRRSEATMDMLIDHLFCIADRIGWEHVGLGSDFDGIYHDTQIEFDSSDHVAGIASVIPGLEDCSTFPNLLKAILDRGATEAQLAQVAGENILRVWQGVADTTARLQTEGMAPVEETWDQRKCWRYDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAC8</accession>
    <name>A0A9Q8PAC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartokinase</fullName>
            <ecNumber evidence="8">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07378</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + ATP = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="8"/>
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        <property type="protein sequence ID" value="UJO18817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763183.1">
        <property type="nucleotide sequence ID" value="XM_047906526.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07378"/>
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    <dbReference type="OrthoDB" id="4323675at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000033">
        <property type="entry name" value="Aspartokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2130.10:FF:000001">
        <property type="entry name" value="Bifunctional aspartokinase/homoserine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000023">
        <property type="entry name" value="Probable aspartokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054352">
        <property type="entry name" value="ACT_Aspartokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499">
        <property type="entry name" value="ASPARTATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499:SF59">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22468">
        <property type="entry name" value="ACT_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="484"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="547" mass="59492" checksum="78548A673D421062" modified="2023-09-13" version="1">MDFPLIRAERPPIDATNFINGILGNRRPHVPEKNVPGGGNWVVQKFGGTSVGKFAVKIAEEVVKAGLDPKTDRRIAIVCSARSTSTKSEGTTNRLVRAAHFAEEKGSGQFHGIVETIRVDHIQAGKEACKRCGEHGSNKILEAYEAEVNRECQLLVKILESAQFLGDVTDRTNDMIISVGEKLSCLYMTALLQSRGVPAAYVDLSNIISLEIAKTVDETFYKHVGKAIAAYIYKLGPDTVPVITGYFGNVPGGLLNSIGRGYTDLCAALTAVGLGAQELQIWKEVDGIFTADPRKVANARLLDSVTPSEASELTFYGSEVIHPFTMDQVVQALIPIRIKNVMNPKNKGTIVLPDPEDELRVRRPGLFRGRSSSNLLNQEKARRPTAVTTKRGITVLNVHSKKRTRAHGFLMSIFQILDKNGLSVDLISSSEVHVSMALHSEIALLSGHSEEEMKIESDALQAAVDALSVWGDVDLVPGMAIISLVGRQLRSMVGISGRFFSTLGDHGINIEMISQGASEINISCVIEEANADRALNVVHTNLFTFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAE0</accession>
    <name>A0A9Q8PAE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763178.1">
        <property type="nucleotide sequence ID" value="XM_047906519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAE0"/>
    <dbReference type="GeneID" id="71987249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07371"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="905" mass="101357" checksum="8692BE94CDE860C2" modified="2023-09-13" version="1">MGVTDSKISFKQSIVRIGGEVNIPVNDAIWQQMFALPESFGDVASLCSVSDIGCLTKSNDNNRPPPNTQVEPNKNLETLLYALIRHLKTLQEQHVYEDDQRRTNNEILNCMRILTRVLPFIYEAQHLKDWHNSFFWEPRRPTCYWDKRRETGPLMDGLNPSEKYEKSFGDMHVGKPLGQETLEIVTSYLFFSGFTLPKRVNDKGKPDLEIVAKVWQTGIGSKVSANCTKDNEKNQQEVIRLLIALMSKTMYIQPNDVPLVDVKALTFMTTGLSERMVKAIVCSTMNTALKYNPNIWSVPVEVATGGDHKKHLVTNCLQLLLALLIYPPPDGAKNQFRQLAGRLKKPEDFQFVNQGLNQVLSQPIHNNFSYSLAKDKAVAWAPEMITLLWELVQCNKNFRRYLVETNSMLDYVVVILYYCLDAMTDAAKHGILRAGVFFLQTMSTEPGFAIKMNEVFRHPETLPPVMRIPNFHGSYTDFLICSFHTIFVSCEGKFEAIYPALLTVLRNIAPYQRNLARATSTKMQDMFQRMCSAQWLVNKENTDVLIIEYLDAVNSILGNNYQENRKFVEVLVASRSRFKALRAFTLDSALDQLNRDAQHRKDRGEDVSAMRSPISRTTSLDSVRGPPSARAPAPSLGDVQEHETFSIGDDDDDDETPIPQSDTVNRASAEDASSPRLSERARGKQPAVSVASTSRTPSTTSLPSLSTSRSPNVSQLQPSKEWLDSWLPQVQAKLEPILHIIDLAEKKQLKFKEYGSKSAATTPAATDVPSTPTKQSLEERRKATEPSELASKPGEEEDSHQADGEGGFQAERDSPPTTTRPPTGFQWTAVAIGWYTALIWSRIYLSEAEAFQGPGGLYSSTDVRLFSRRSAAQEISLRSPRGAIDAVGDGLVKRISSMSLPTGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAE6</accession>
    <name>A0A9Q8PAE6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763204.1">
        <property type="nucleotide sequence ID" value="XM_047906135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAE6"/>
    <dbReference type="GeneID" id="71986865"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06987"/>
    <dbReference type="OMA" id="DYEEYCK"/>
    <dbReference type="OrthoDB" id="10492437at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="20774" checksum="74F71EF65240C73E" modified="2023-09-13" version="1">MEPFISLHPVRPYHSYNQPIPNAEALRKDFFKPGNQGSTEVFMVNTWDPTTGRIRPMLDTDGSKPKVIERKGEDHLYPFQIWLLKVADDEVLLKHKDIIESDYTDMCALARQYAGSFDASREAKGWAEKVVKEAKSEVEYLKTMIKEMNEFQPRIMGLTPEMHEQKMYAEAQDTGKFGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBS9</accession>
    <name>A0A9Q8PBS9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763912.1">
        <property type="nucleotide sequence ID" value="XM_047909764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBS9"/>
    <dbReference type="GeneID" id="71990494"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10616"/>
    <dbReference type="OMA" id="HEPILAM"/>
    <dbReference type="OrthoDB" id="5357734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37576:SF2">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="68327" checksum="75371CDF45AE69F5" modified="2023-09-13" version="1">MVANEAVSPISISPVEDRRKHAPYTDDFVDLDLIEPQLELRDFDDKRSHWIPIPQEVERSRPPYNLDTTGTSSAFRWGPVLGLACLLFVFLSIPAAAVVLSVSDGQLVMRWNIKPNVYLAVISGIGNKLLAFAAFQGAVVTWWLRAMDGSTLRQLHLDWAAGPGNNLWYALSGYRHSGLLAVSTLCAAIVFADGVLLQSASTVIQASVNEQVVLHVTLAPQIPTDFTGSIINDSAVFDYVAFNPGFQSVLRDFVVQAAIPAPITGCTGTCRATVTAAAMSLVTCVSEPPVEINLPRLNSSEVAVPYMCDEDSKSCPLLSIEPRPYFMSQELIRVVIGLTHFNDTTNTGQFVLKRCIFASATAEYAVEVHNNSTVTVFDFGEPVVQTIANNTRWLPAPGYSNSTLGGIGSLAWISMRTSLNVGSDRTYDDVNPFTATLIGNLAGYFNGSEFPRWIDPVDKIKALLNEIAFRTSVQAASLMDQETLLENIDEDLRVEYDAEGTRIDQMPTYQTRWKYFVFAATLDLICVVLVALLYRDYWKLGRSMSISPLETAKAFDVPLLRYLPSNMNGKQLAQVAGEVRVRYGAFESDELDGEHASRRLIFHDPSRVYRPMNTFTFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCF1</accession>
    <name>A0A9Q8PCF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764269.1">
        <property type="nucleotide sequence ID" value="XM_047909350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCF1"/>
    <dbReference type="GeneID" id="71990080"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10202"/>
    <dbReference type="OrthoDB" id="10593543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="36850" checksum="D6EF96618461DF13" modified="2023-09-13" version="1">MSRNGPYQWICLRAIKPRPQTRTLSTEYSPPENTQDPYPTPDEPTAKTADFKSYLQSQDTIHLSTTKHHLSAIRHTAQTIKSFASTLPSASRIALLQQTGTPPYTTSPFRAASNNPTIPTATLLAEIAKLDNNLTDLENTPYPSETDSAAVRKAEKFKKKLSLWTKREKEEELERLRAAEVSHRTRFMRSMEGLKPHVEALNEVGRRRRRRRGGAAAGGDGQDEGGLEGVARKVQTVGLGSGATEIEDEREEGGRVPNPFVGGVKQKEKKAVTDTVKTKQRKTATDTVNTSKDTTQAKETAPTTAADAVEVPKPKKKMTLAEMQASLSKQVSNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCV6</accession>
    <name>A0A9Q8PCV6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphoglucomutase</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Glucose phosphomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_10664</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:68748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:68752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764453.1">
        <property type="nucleotide sequence ID" value="XM_047909812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCV6"/>
    <dbReference type="GeneID" id="71990542"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10664"/>
    <dbReference type="OMA" id="WIQDRAN"/>
    <dbReference type="OrthoDB" id="2291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000005">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000006">
        <property type="entry name" value="Phosphoglucomutase PgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="17">
        <location>
            <begin position="14"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="18">
        <location>
            <begin position="185"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="299"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00056382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO20087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="60641" checksum="AD8DEFFACDA13DAB" modified="2023-09-13" version="1">MSVKDVQTKPYGDQKPGTSGLRKKVKVFQQENYSENFVASIIQSIPEGAQDAFLVIGGDGRYWNPEVTQLIAKIGAAYGVKKLLIGQNGILSTPAASHLIRIKKATGGILLTASHNPGGPDEDFGIKYNLANGAPAPEGVTNKIYDFSKSITSYKIADIPDIDLKTIGTKTYGPIEVEIVHSTTDYVQMLKDIFDFDLIKSFLKQHPDFKILFDGLSGVTGNYGIDIFEKELGQKGSTQNCEPKPDFGGHHPDPNLVYAKSLVDRVDKEGIHFGAASDGDGDRNMIYGANAFVSPGDSLAIIAHYADLIPYFKKQGIYGLARSMPTSAAVDLVAKKKGVKSYEVPTGWKFFCGLFDSDKMNICGEESFGTGSNHIREKDGLWAIVAWLNIIAGVGQQKNETPSIKSIQHDFWNEYGRTFFTRYDYEGCESEGANKVVAHMTDLITTKKGEFVGSSVAGRKVVEADDFSYTDLDGSVSKKQGIYVQFDDGSRIVVRLSGTGSSGATIRLYIEKHENDKSTYGLDAQDYLKDNVKLATDLLKLQEFVGRTEPDVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDA9</accession>
    <name>A0A9Q8PDA9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_10266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764668.1">
        <property type="nucleotide sequence ID" value="XM_047909414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDA9"/>
    <dbReference type="GeneID" id="71990144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10266"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="5"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO20302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="458" mass="51663" checksum="CE21E60AF8B8EC69" modified="2023-09-13" version="1">MPDNATLLQGFEWNVPADGKHWKRLLHALPVLKECGIDNIWLPPGCKASSPEGNGYDVYDLYDLGEFDQKGGVGTKWGTKDDLIALSQKAQELGVGLYWDAVLNHKAGADKKEKADAVEVDENDRNTEVSDSYQINAWLGFDFPGRGDKYKNKGWSETVDDEQGNADFMMFADVDYSHPEVEEDVKNWGTWIVKEVGLQGFRLDAVQHFSERFTNDWVEHVRKKTVKEVFMLDKMNHRFSLFDAPPLYNFSRLSTTEDADLRTVFDNTLVKAEPVNAVTVVMNHDTQPGQTMDPKVEGFFKLLAYALILLQDAGYPCLFYGDLYGISGDNPEPPSCGNKLPDMVLARKLYAYGQQDEYLDQPTCIGFVRRGNEEHHAGLAWVMSNAGPGEIRMAVGEMHAGQVWTDVLGWQQEGVEIDEEGYGLFKCPGTSVSIWVRKDAKGRDRFPVQFDHEIYKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDG7</accession>
    <name>A0A9Q8PDG7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764768.1">
        <property type="nucleotide sequence ID" value="XM_047909571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDG7"/>
    <dbReference type="GeneID" id="71990301"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10423"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="771"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="667"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="855" mass="90347" checksum="2FCB888F3C232780" modified="2023-09-13" version="1">MRLKSAAAALAAMTSLSQHGVTGLVMVTKTIVETVTAPSDGACQDTFLPQKSQDYTVKSNLATDMQPAEEMVTGPSTITTWITTTTTVGLITSTSVLNALEARSAVMSLDCGCKINKENGFISCPSEDEMLSGSHSCGYPEGVPAPETSASHDSVAHTNTVHQSNSMGAKQTARQSDIPPLTQRRDALNSEGFIDRCFYKPGTRFDITSTPVDTSAPTYSFDFNPTLLGKRGPFFIDEKGQLFDDSGCMGTFDTFSKFRLRSPIAFKFPSLSTWSACGEGNTLLFGTTSQFYQCGNVTFPAVWSTLPRGYSEVSAQEGYNVTTCVKAKLVWNEISKTDLKKRQNNPDPSSYTWPATNCPRRDLCPPQPTKLAKRGLQDDVLGDGIRHIDYDSTTGTFAFREDVETLAPGEDGAPASVQTIPARTMVYKEEPAHATAVAKNQKRQNQKRQNDGFIMTSFQTETTARSSMVPKLQAPTEASTTDLHDRPSGTATHVARDFTPVISVKTYTFWPRTTSITFHYADTSLAVVPKSWLATTFTASAQAVPITLTETFNVTASDGKTVATNVPMTATITDWSLIVTPTNLLFGVIDDYRDSPDTTTASETAATFTATGYIPAPSPASTSTAVPGNLPATGTSVSGLSTLLAGASSSGCFISCGRPLPTTTFLASDSGTSSSSSPSSSSTTLTATSTASDTGHPGARGLPFTSVWSTTTVENGTTCTVTLTSENANPCQMAHGCGTATRTVTTIISAAYTVLGKQTISNDAYTTTYTQFDNPEPGDGPGPTKRDGDLEVSTLDATSTTEPISPASTAGKTPMISSAPPPQAGGASKVIESDGSTQLIAATGMAFFAVLAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDG8</accession>
    <name>A0A9Q8PDG8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RCC1 repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764758.1">
        <property type="nucleotide sequence ID" value="XM_047909123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDG8"/>
    <dbReference type="GeneID" id="71989853"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09975"/>
    <dbReference type="OMA" id="GWGNCRK"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF5">
        <property type="entry name" value="RCC DOMAIN-CONTAINING PROTEIN ATS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="11"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="123"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="176"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="271"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="368" mass="39132" checksum="6ED4974E664FE630" modified="2023-09-13" version="1">MASNKHNDIKIYAFGSNGSGQLGIGHSDDVSKSEPVVYAFHSNVTTTGETDANVQTIACGGNHSVMLLSDGSLWTSGDNSNGRCMMQVDGNGTAWHRQVDLRPVKHIAATWNATFFVHTDDATQVFVAGSGNTGELGLGQGITITSTVASMRLPPGQNIVKMTAGMGHIVVVTEQGEVWGWGKGRNGQLGKPAENVWVPRKIEGVPWPAVDVVCGKDFTCVFSDTSTQECLVLGVDRNDRFGVKATAPVKVPRWKQVGASWGSIFVLSESGQLTGWGRNDHGQLPPPDLPPLQSFAAGSEHCLGRTVDGKVLAWGWGEHGNCGDRTDPNGDVKGRYNEVHMPQSACAVFAGCATSFPVTEKQETSAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE17</accession>
    <name>A0A9Q8PE17_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765109.1">
        <property type="nucleotide sequence ID" value="XM_047910579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE17"/>
    <dbReference type="GeneID" id="71991309"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11431"/>
    <dbReference type="OMA" id="WFHPYGR"/>
    <dbReference type="OrthoDB" id="422736at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="57955" checksum="E0DD207BCDC6398F" modified="2023-09-13" version="1">MKRETLEHIFQQHHDPAAHDSEDSVGLLNEDEKRQTSPSPLQGKFANSRNRKVWLYLALFGIALILIALALPTKRIRGIELPFIPATPASHLRQEDHFLHIVIPQIWSPVGTVELCKTLLTASTLDYPTPWTVSWNSTVDADGEVANAALNKIQHVSAWLNGMPEEREDDLVAILGNNKSWFQVRPEVLLKRYLGILEKANKELSHKYPSDVLETREIGERVVFATEEQCPSEDAGRCQAVEAGGKSVHYLSADFSMGVLKDVKLLWQHAASKALQLTVENATFDEYTIFASLMSEQEQYRQEARQSRRQEERQNDHGTSIDFGMTLDFKQELSYAAPSNTDETEWIKHIKTSKREVRKWTSPPDLYLPKDITASEPPFWTVDGAEVPQNATWHDVQLLTTTATNVVPAIVQRGPHSDPLLAQGWWKKMWFQPYARRLLDTFVLTPLMPVAVLAGMGGNETRYWSPHWQRIGVMQAENVKFKKWNDVCNAEEMAQALFLDGEGSWVDPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE43</accession>
    <name>A0A9Q8PE43_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765127.1">
        <property type="nucleotide sequence ID" value="XM_047910233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE43"/>
    <dbReference type="GeneID" id="71990963"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11085"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000263">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="79"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="622" mass="69479" checksum="C5DDE2B45F7138BB" modified="2023-09-13" version="1">MLNVDARWTRSCKAALTTSMEKGSNPVATKPLTRPTRLASKPVFFFSSLLALLIFYNFVPQCHHAVQSFFTLESWADPSPRVELKQGTFIGTHLDNENHPVPVEAFLGIAYALPPTGERRFARAVPMPESREVFPATDYSLRCPGKQLLRIPGTPWLESSEDCLTLNIFRWRGSFSYQKKLPVLVYIHRGAFNRGFAAMHDTASMLAWSEEPFIALSFNYRIGALGFLNSQLTEKEGLLNLGLHDQKLLLEWVQDNIEAFGGDPNDVTIAGLSAGAHSIGHHIMDVNEERTLFHKAVIESGAATSRAVHPANSKLHEMQFEKFVAQVGCSGKKGSEILSCLRQAPSEVVTAAQTTVFDEYNPSVRWAWQPVIDDDIVSRRPLDAWKSGKWHKVPIMTGFNHNEGTMYVPKKVQKSDEFNSFFATLLPQLGKAGLKKLAELYPDPAKAESSPYVDTRNLTDLGIGEQYKRVEAAYGHYAYVCPVRQTADFASAGQEPPVFLYHWAVNKAVIGGANHGDQIWYETMSPLVRNVSPTHDEIARRFNSYVTSFIVTGDPNTLQGRKAISRPRWGKFSEGKKTMVFGAGNDEAAGGSQVGVASEWVDDEWAREECKFWWEKSEVPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE49</accession>
    <name>A0A9Q8PE49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765145.1">
        <property type="nucleotide sequence ID" value="XM_047910313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE49"/>
    <dbReference type="GeneID" id="71991043"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11165"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="32773" checksum="E79ECB26ED115643" modified="2023-09-13" version="1">MDPRKRKSSGLGDDSAGESSATRVREAQYTRAQDIHRMAQSMPESSYPNAQGRFQSGPDHAPRITPDEMQDVINQSLQSPLALTYYNRLGATPLEQVSLDATPLEQVSAHDLAQTLLNRMASGHMLKQAMRERLHEMTRPEPSALQPPTIPELQSQMYAPTYSFPSSGSISAIPQVVMANSAVETNTQIPGQMYASQSNSAIPPAFTMTTPLANQPQFPTYPSGNPGHPLPQGSNTPNDSPMAMTALTGCQDTSTIAPVDPRGTCRFCITHRKLWRQWNACFCRRPYEWKCGHEHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF16</accession>
    <name>A0A9Q8PF16_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765610.1">
        <property type="nucleotide sequence ID" value="XM_047910805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF16"/>
    <dbReference type="GeneID" id="71991535"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11657"/>
    <dbReference type="OrthoDB" id="10616707at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="62175" checksum="534585402A985F8E" modified="2023-09-13" version="1">MSDTTPTAAAGEPRVRRDMISNDVPMELLLHIFSYGLTITDLVNLASAQKRFTNLRPATESILFSSITLRQPPNQQQLYGTRLQKMLRSFARNSSVRKCVKHLYIPHFEKISPARRDRDGNMAILAAKAFCGVRDWPRALQDHFRAAQNFLGQDREVELVLLLGLMPELRSLRLGMVSFTPRTDNFDWTVSILGRILDQTTMPTVADEKLFLGNLTHVHLDLAQEMLDNDDHLFLFDLHIAPLFLRLPTMRSFKATGGRLKHLIRDWKCADRASKVTSLTLVDCDLGTDALINFIRACSALKSFLCLRSRIHQEEPPVGVVWPLIVGELESHKSTLHHLAITSYSKIDVDSVPNATGPTDLAITSLRRLDNLHYLDLDDEAIFGISAADAWRVRPSVRHDAIYLLSLLPPKLQHLVIREGRQYDPLPNRTSLWSNDCYEFGRVLLEHNTLRRLDAIGFESVDRLKEPMVRHFPDLSIKRNTWLKAYRPSGQSIRMTKRGVDGSPVMEPPWLKRGVGIWVRKEDDSESDDDDEEEEEEEEEMMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFD4</accession>
    <name>A0A9Q8PFD4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear polyadenylated RNA-binding protein NAB2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765935.1">
        <property type="nucleotide sequence ID" value="XM_047908894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFD4"/>
    <dbReference type="GeneID" id="71989624"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09746"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055046">
        <property type="entry name" value="Nab2-like_Znf-CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22683">
        <property type="entry name" value="Nab2-like_zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nab2-like CCCH zinc finger" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="456"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="517" mass="55198" checksum="B8E08E9DF08B1B38" modified="2023-09-13" version="1">MAASVDITGDLQTAIQAAVQPKLMENGWVVEENDTTLSEYVTMMIVNGKDVAGVKSELGGDLLGVGENDPGVGQFAEWLFNTVQQLSAPQQQEQMAEAPQQDQQLQQIPSTQDAQMEDSTASADAPPTGPRSMRNGNERGRGPRMMRQLNNSMGRPSDLPDKLSRIKGAAGVGAGRIDSHRGRDSAPRGPRNNSITHGLQRVMGTGRGGHQNGANGNFMNGGQIRADQQMQFMQMMEVQASMVAQLLQQQNGGLPQTGRGGHPQRGAGRGRGRGGARGGGNQNPALHAVDGKLPDGPLPSGPNGSGMDIDGNNGHSTDAFSTACKYNTTCNVPTCPFAHQSPAVTSNIQVDLTDTCTHRVACTNTKCTARHPSPALRNGHHAGGGLSSIDCKFYPNCANPRCPYRHPTAMPCRNGPDCTTPGCTFAHAKIMCRYNPCTNALCAFKHAEGQKRGKFTDKVWTPEGGEKTDRFADLSKHNEGDEELIRPDQQTNGEGAREQQQESVVPDSQMAELAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY0</accession>
    <name>A0A9Q8PFY0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766134.1">
        <property type="nucleotide sequence ID" value="XM_047908156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFY0"/>
    <dbReference type="GeneID" id="71988886"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09008"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF4">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="38295" checksum="B9B89124E741B545" modified="2023-09-13" version="1">MNGESSLHRRSGFADVSESSGSKGIDHELPVYDDVDSTDDDAWRDTARDRRDMLRMGKKQEFQLPECTGLRVGVYGIVGVRSGVVVCGVLEWWLCWTVLSQVSRRWPSYLGNVGLGILSLVVMLFCIGPLEGVLETDIPYLLLFNNTGSPALSIVLNVILFLLIYAGNITALATCAREMLAFARDKGLPFAKLIGRMDPKWNIPFNAVYITSVAVVLLSLINLDSTLAFNIIVSLSLLGLLSTYMISIGCVLLKRLKREPLPPARWSLGRYGLAINAFAFFYSAFIIVFSCFPTNLPVDLSTASWAPLVWAGVILISVGFYVAYGKRTYTAPVEFVEGRKAAGVGLQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGD7</accession>
    <name>A0A9Q8PGD7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrile-specifier protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766377.1">
        <property type="nucleotide sequence ID" value="XM_047908878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGD7"/>
    <dbReference type="GeneID" id="71989608"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09730"/>
    <dbReference type="OMA" id="PRDNDVH"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="36812" checksum="D199F78B0FE78CA7" modified="2023-09-13" version="1">MATQATLTAKWTKMTNGPQLQRSSHTVTTVDKTLYIFGGELKPREPRDNDLHKYIIGSGTDVTTLSADSQGTAPSARVGSTTAALNGKMYLFSGRGGPEMAPVDEEGGLWILDAGAEKWDLVKPASSTFPEARSFHCTTNDGKETLYIHAGCPEKGRLADLWSFNVSTKEWRQLASAPDPPRGGTSIAFAEGKLYRMNGFDGQHEVGGALDIYDPASDSWSSTDFNPDGKDGPGARSVAALIPVKRHDGVYLVTLFGESDPSALGHQGAGKMLSDVWAYSLREGKWLQVVAEGNKPEGRGWFDADVVSLDGAFPQEKIAVVGGLGESNERLDDLWLLTFGANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGP3</accession>
    <name>A0A9Q8PGP3_PASFU</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766448.1">
        <property type="nucleotide sequence ID" value="XM_047908818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGP3"/>
    <dbReference type="GeneID" id="71989548"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09670"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="36440" checksum="00402D3604AF63A1" modified="2023-09-13" version="1">MANLSTMKSRLRNGKIRGGTRICHLLLLPIELRLEIYEELLQHNGVTRKTLSPQILVTCKQIYSEASKILPANTKKMALVRIKTGRIRCDIRFDSSPAVVIPMYEERKGLCLDAALEAMLPIFDGKTYIMVYINMTSSADKTWQQVNQMLYLLVSAATLSPTVRALEVRLKSPTATTTPLDNYAMLSSTTRTLEVRLKSPTATTTPPLEYYAMLWPLTRSLGPGTDLYIQGCPDDTVLEAIKNATQPQNQVPTAALARWISLKREVDDLVKMVEEAGITGAGVRFLPRAMARMRPIAGVVQKGADEVIGGGGVMWLRRCLCWASRGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGU0</accession>
    <name>A0A9Q8PGU0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGU0"/>
    <dbReference type="GeneID" id="71989525"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09647"/>
    <dbReference type="OMA" id="TMGIRNM"/>
    <dbReference type="OrthoDB" id="497541at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="432" mass="49844" checksum="476764D5D359CFAE" modified="2023-09-13" version="1">MSYLQAQAQSFLEQVKEVIPHVADAVLNIPWLQVYLALSAAATLLIIAHRLSQLAVLKSWLKTRSRSLDAVKHTEASKQVARRVKPVDRPPGKWQPSDFRRPQAQPYPDWSVADSSPKPYRPFRYGTYHITMGLRNMHWDEWIELDSHYLRYHSDKARRIAERGSRCSYTNPSPRVFDGAVELLEELASYLAERYPSIFTRTSVGIDNTLTHESFDIRPDHLTMNGGKEDPMQLCARLVQDDLAIMFEKEDGQYYLLAGSILLAGFWRLEDKLGMPLSEIHTSGDVPGYKEKLEKGMMNFFRRVQPEKPVLRNNYFIQVDDNLAWSHSIGSEDAETVSWSTAEKNKAIENHYFRSERQSLRRLPRSGGVVFTIRTYFHPITEIAEEKGVPGRLASAIRSWGNDVSRYEGRERYGKCCWSIWIESMRSRARVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH30</accession>
    <name>A0A9Q8PH30_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766704.1">
        <property type="nucleotide sequence ID" value="XM_047908291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH30"/>
    <dbReference type="GeneID" id="71989021"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09143"/>
    <dbReference type="OrthoDB" id="10561691at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7888" evidence="1">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17086" checksum="E45121016FF9BA28" modified="2023-09-13" version="1">MLRLTRRCTRSEEAADVPGLTWDEARAAFATGVTASILEDGAEEGEAAICVSVPYEVDDPAKTRDAVSVSFEAGGQEAVYDCFLLTDGANFSIDAADYSEANVGIAGGELVDGSFTAQRMSDMIVEALSIQRGGRASRMDRRWVMIGSMLMYEHLVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHD2</accession>
    <name>A0A9Q8PHD2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyanophycinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766793.1">
        <property type="nucleotide sequence ID" value="XM_047908359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHD2"/>
    <dbReference type="GeneID" id="71989089"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09211"/>
    <dbReference type="OrthoDB" id="4666063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03145">
        <property type="entry name" value="GAT1_cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36175">
        <property type="entry name" value="CYANOPHYCINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36175:SF1">
        <property type="entry name" value="CYANOPHYCINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040306561" evidence="5">
        <location>
            <begin position="18"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="30729" checksum="10A8DE10B0549C4A" modified="2023-09-13" version="1">MLLTSLLCAAFTATSLAYPLSSTNGTNTTYIGPENGHLVSESIYEKIIELAGGPDAPIVVIPTAGGEETYSNNFTTAVAFRRWGATNVTVLHTYDQAIADTDEFVAPLKDARGVFFGGGTQWRLVDVYVGTKAETAFQSVLDSGGVIGGSSAGASIQGSFLARGDTANNQVMIGDHTVGFGYLKNTAIDQHVLVRNRQFDMSQILEAYPELLGAGCDEDTALVINKNHADIIGSMYCLIYDGKFWLEEGTDLKQIPSPAQRFFFLKPGDAYDLGERRVLSNRTSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHI6</accession>
    <name>A0A9Q8PHI6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-binding monooxygenase moxY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767120.1">
        <property type="nucleotide sequence ID" value="XM_047911346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHI6"/>
    <dbReference type="GeneID" id="71992076"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12198"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF1">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE STCW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="2">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="19354" checksum="4C4378E05E047AB8" modified="2023-09-13" version="1">MAPDLNAVAAGETFDYSQPGSSGYEVNQDYTWKTGRVVLTAVFSDPKNRKIKVLTIGGGVTGILMAYQIQKLCENVEHTLEVLGWRTMVAIQEANVDVHFTAVKEATEKGVVGADGVEREVDTIVCATGFDVSYRPRFPLVGRGGVDLKDKWKVCPESYLGLGILYFPNFITFIGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI57</accession>
    <name>A0A9Q8PI57_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767233.1">
        <property type="nucleotide sequence ID" value="XM_047911594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI57"/>
    <dbReference type="GeneID" id="71992324"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12446"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="60302" checksum="F707ACDB92A0956E" modified="2023-09-13" version="1">MPAFSAYIGTCSKSRGASVSTLATIHHFPITARKQFSSMANRASTKRPEDFVQFLNASPTPFHAVRSAKLRLEKAGFKPIKERDSWNSTLQPGGKYCLTRNASTIVAFAIGSAWKPGNPVSMVGAHTDSPCLRIKPVSKRSADGFLQIGVETYGGGMWHTWFDRDLGAAGRVMVKGKDGTIEQKLVRISKPVCRIPNLAVHFGGYEPFEFNKENQLFPITGLVSAELNRQGKTAEQIKKDEGEKEKEAGFEPLKTATQRHHPYLIDLIAQEAGVQVDDVLDFEMVLYDTQPSCIGGINDEFIFSARLDNLGMTYCAVEGLIQSVASPSALKNDPTIRLIACFDHEEIGSQSAQGADSNMLPSVIRRLSCLPANHDDSEKSYEKVSGDVDNTTAYEQTLSTSFLVSADMAHSVNPNYGGKYEPEHKPHMNEGTVIKINANVRYATNSPGIVLLQEAARRAKPTSWQLPEAKSKDRGVPLQLFVVRNDSRCGSTIGPMLSAALGARTIDVGNPQLAMHSIRETSGAHDVEHGVNLFDSFFEHYGELEGKILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIM5</accession>
    <name>A0A9Q8PIM5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767607.1">
        <property type="nucleotide sequence ID" value="XM_047911088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIM5"/>
    <dbReference type="GeneID" id="71991818"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11940"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="25138" checksum="36AA6CF2C5AB6598" modified="2023-09-13" version="1">MGGSGVGVAIGERVESLDDEAEIKVDEVEISVDIGDVIVVRDDKLLGSVDRLDEAVEEDADMLVSVEKVGKVVDVLVSVESDSGELADDELAAELVISVDRVDELVSRDEEPVASVGRADEELVGEVAVSAGMLEAELVKSLVASVESNDEEPEDDELDARLVVAVEELETTLDDKEVVSVERDDEELEDDEPVPELVVSVEELEDGLANEELDVEGLDVEVLVVVVVTMGTHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJD1</accession>
    <name>A0A9Q8PJD1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767857.1">
        <property type="nucleotide sequence ID" value="XM_047911722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJD1"/>
    <dbReference type="GeneID" id="71992452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12574"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF1">
        <property type="entry name" value="AROMATIC RING-OPENING DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G00640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="9"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="29368" checksum="F600F30FD631B447" modified="2023-09-13" version="1">MMLGEESESADYWKQAGDEALANGIKGVIMMGAHWDATGDAIEVAMNPSPGKSPVAYVHPSKYVDYKLEADLPTGERCMQMLKSEAFNVRPNPKFEWIHDTYLILTRMFPQKCPPPTTTIVSMNARFDPHFHMRIGSTLRPLRKDGYLLIGTGGARDNFAQETPPDGWALEFRQSVEDCVSNNRGPALRRAVTRLMKHPRYRDAHATDDHFMAACFVAGAAGDWEDEGEEGGVLRAETWELTNMCNSQFTIGGWGGCGGWAVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJF1</accession>
    <name>A0A9Q8PJF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767961.1">
        <property type="nucleotide sequence ID" value="XM_047912370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJF1"/>
    <dbReference type="GeneID" id="71993100"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13222"/>
    <dbReference type="OrthoDB" id="4153866at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="462" mass="49888" checksum="9BEB639683C4220D" modified="2023-09-13" version="1">MVISKATPTCNLLILIFHTTQRPSTSGPLQDNSDLDTHTTSTTATLAKLTALLMIARIQCAPLEHQTTDAISTCGPQWMPASEISIGNGTDIRPGYDSAVQRFCDAADGHTVMPDEHLSMATEVYLNGGKDASIYGVQGFAYFEILNKDQASPGHEVTAEKCSKYFLALSAEGGKCSGSINHDTKGGTFEVGNEEQSYTALGGEVPPEEPAVNRIFIGTLTPQTPNKGSGPSLDPWPLDSLNDIKPTRCHSHNDYDRSIPLFLAMSAGCISFEADVHLLEGDAIIGHDSPQAGRSLSAQYIHPLRAILDHNNDDKPGTIMLYPARPGQSVTLVVDFKSSEPELFGVVLEALQPLRDGAYLSTSKSGEFVQKHVTIVLGGSAPFDRIDSDDDNPNRDVFYGAPSDHWDSKYTSLNSFYASQDWTTVEGFDWLGAAMNGGDNPVSKQAKVVHDAGLRLTYCRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJF3</accession>
    <name>A0A9Q8PJF3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768125.1">
        <property type="nucleotide sequence ID" value="XM_047911790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJF3"/>
    <dbReference type="GeneID" id="71992520"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12642"/>
    <dbReference type="OMA" id="WRKWASA"/>
    <dbReference type="OrthoDB" id="3644822at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="24774" checksum="CFB4326D2C5B3677" modified="2023-09-13" version="1">MATDSRTWIGLKGIALASTFAIASSQTTTALVFIPALLRPLETSRSASSSPSQPPSRPASSLRVPQLQEESGRLTPSATPSSSKAFFDFSIGSSGTYKAVAQQFARMEALNFPFVVPIELFAIGVFSVSAYRARSVGNLEWRKWASAAAILGSVFPYRIALMEGLVHKIKRIGGDEEKVEPYEDAPPDREMERGNTVEFVRSWNVYNVARAGIIYVATFTGLVAFALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJW7</accession>
    <name>A0A9Q8PJW7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial intermediate peptidase</fullName>
            <ecNumber evidence="4">3.4.24.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Octapeptidyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_12809</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.</text>
            <dbReference type="EC" id="3.4.24.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="4"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768100.1">
        <property type="nucleotide sequence ID" value="XM_047911957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJW7"/>
    <dbReference type="GeneID" id="71992687"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12809"/>
    <dbReference type="OrthoDB" id="17530at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06457">
        <property type="entry name" value="M3A_MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033851">
        <property type="entry name" value="M3A_MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="16">
        <location>
            <begin position="298"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO23734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="988" mass="111188" checksum="408C0F14197E5872" modified="2023-09-13" version="1">MFKRLEQRAWTCPQCLRQQVRQSRRSLVTSSRTKGAAAAGAVADDYQQPISTAAPSIAHDDRTLRQIFDSPRFWKDFSSKTKYHSGGKSAGLLQNRYLSKPEGFGEFANVTLQKCQKIVAQVLKYNTVDQYKRITRDLDRLSDLLCRVIDLSDFIRSVHPDRQIQAAATQAYAAMFQYMNVLNTTPGLNEQLKKAASIPEVHASWSVEEKTVAEILIRDFSKSAIDLPEKEREAFVALSDEIAEVGNAFVDSMAPEKPYLQFSSSKMKGMDPVFVKQLTKWGNVTLPTEGMPAQVALRTVEDADVRQEVYMANRTSSKDNLQRLERMLRLRAELAKLSHYESFAHMTLTDKMAKSPEAVTSFLDGLAQVNSPHAREELRELLELKKGDAHSLNRPEQLNAWDRDYYTTQLMSSMRSKARTPDVLSAYFSLGTVFQGLSRLFHRLYGIRLVPHETLPGETWNSDVRRLDVIDDHEGHIAVIYCDLFERPGKSPNPAHFTLRCSRRISSEEMHEAAEISSHSSSPFSTAQEAVNDGLATNFNSRDNNALYQLPTIALICDFSLPPQGSKRPTLLTFRELTTLFHEMGHAVHSICGRTALQNVSGTRCATDFAELPSVLMENFASAPEVLGLYARHWETDTPLDPSRVQERVEIDKRMQGAETESQILLAMLDQEYHSSQSLSWQDAGESTKVYQNVWNKYSSVPEPQGTSWQGFFGHLFGYGATYYSYLFDRAIAGKIWRDVFQRQQGDAVNPAQGALFRGEVLRWGGGRDGWRCVAGVLQEKDGVLAEGGKGAMEMVGKWDGVVYGFANQKIVVQQLFFPTCHVEANWCSAPDHCECCLGLDQQQAKTYHLSRPTQFKQRYISILFIPFLLHLTSTAAQPPLPPLSNTLAPLYGMGVLDKYPDECVISLHDGQTLEKHFRTLAIDQHAFAALREFTWGYEATMSASLRDKLIRRDPGVLAVETSRPAYAIEAVDVVVCEPEGGPPWWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK99</accession>
    <name>A0A9Q8PK99_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768295.1">
        <property type="nucleotide sequence ID" value="XM_047912177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK99"/>
    <dbReference type="GeneID" id="71992907"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13029"/>
    <dbReference type="OMA" id="VILDVWY"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="38901" checksum="269372301E4D681B" modified="2023-09-13" version="1">MAESAFFPLVIYYQTQFYRRGELARRLAVFYAASDIAYAFGNLLAFGMFQLDGGVLPSWKYLFALEGSLTICGAVVAFLFLPYSAEKATFLTAEEKRLAFYRIQTDSSAVVEEKFNLRETLKILKQPTSWVILAIQMCLSIPLQSVSLFLPQIVGRLGYSTIKTNLYTVAPNCAGAVMLLILAYSSDYTRWRFPFIALGFLFTFCGFIIYAAIDVEHNINVAYFACFMVTWGTSAPSVILDVWYNNNIADENRRMLLTSIGVPTANMMGVVSSNIFRTQDAPDYIPALATTAAFGALGILLTLALGGWMILENGRRDRRQGVIVRAQDVPTERLKEGPDCDDFRWIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL37</accession>
    <name>A0A9Q8PL37_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7587 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768773.1">
        <property type="nucleotide sequence ID" value="XM_047912686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL37"/>
    <dbReference type="GeneID" id="71993416"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13538"/>
    <dbReference type="OrthoDB" id="3633938at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056009">
        <property type="entry name" value="DUF7587"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24494">
        <property type="entry name" value="DUF7587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7587" evidence="1">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="326" mass="36370" checksum="02A19CBB6DA13C1F" modified="2023-09-13" version="1">MGSAKINDELKQTIQKRMQTGTPRFLFRVWHAESGGTVGLNTINRITPLRFRLNPTHSRNFFDNSIEDLAQTAEDHIQSGKIPEGTMYSSWTQSLPQALVWACIRLKTRSKHLHLCILDTRELSSAQVVLHTYAMRELLSEKISEWVDYELLAYGPLEGPVYKAVPLNDIPKVDLERFYAGFCQNMLNPKVGEGFFKKGDAASLLSAASDIGRLFGEYSLPMQVHLLSCMSHTDINHATIVDALSGPTVPEEWLDDPDPTDLDVAGHTEAQRAAIILRDLAIRAHRRGLGVSTSGGRQDLQKSQELKRTHMLAGGVTPHPMIPKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL71</accession>
    <name>A0A9Q8PL71_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768790.1">
        <property type="nucleotide sequence ID" value="XM_047912666.1"/>
    </dbReference>
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            <begin position="1"/>
            <end position="70"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO24424.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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            <begin position="34"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO25251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="32962" checksum="D2BD9516B7FD01BC" modified="2023-09-13" version="1">MNNMMFAPLQPQSEFGKRLLANSEAQAGSERNDISTTCQLSPLRSSSRKAGRPRPLTLLDLPGELRNRIWAYSCGYLQLDLRCMMTTAERIAQACPEVRTELQSMYYENHIFMFNLRNLQIGRRVPTWRTWMAGIQNEDASRLKNLVFYFPDFMLKASITPAPLAKDKKLRVDFDFRPNETDSINRPYPPWLKHAADSRLDVLSEHLCAFGNMDGRLGRWGVDRIAKIAFGMVAWMHLGRIRHDYPILYAQLEDDELTYEEEMLRHGWTCGQCEWACEMTGVLDA</sequence>
</entry>
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        <name type="scientific">Passalora fulva</name>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="10103" checksum="4D69655563979894" modified="2023-09-13" version="1">MAQETDDTGAGTTVFQTYELLENIMLRLSVKEILIVQRTAMHWRLVVQRSQDLQEKLFFKAAGEPIRPIQEDGIVHPRSPHSIRRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQT5</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19043.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="38673" checksum="B7AB158B1DB71BE9" modified="2023-09-13" version="1">MAEEAPQVSYEQLALIEHEFDEIDSEIMRKQYELSKGAYAKRAEAVAKIPSFWALVLEQAPMEVDQYIQPTDSQIFAESLVSLNVSRPELDAGKSNGSSRSLKIRFEFKPNDHFEESVLEKEFSHRRSSDGWQGLVSEPVKITWKKGKDVTEGLTDGALALWEARKKKGDMKATDSKEYTELKKKVEHWNGANTSFFTWFGYVSGRRWVSAEESEAANKEYTEKLQAKKNGTAKAEESEKEDDEEEDDQEDDSEVEVHEAGEDLAISFAEDIWPNAIKFFTQAQESDDLSELDFESDDEMDEDDAEGGDDEPVDIRALVQKDGKGRKRQSDVGPASKKQKK</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71990078"/>
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    <dbReference type="OMA" id="QWYEALN"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO19901.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="62102" checksum="9E536AA895F431BC" modified="2023-09-13" version="1">MDRGGSSSSSATDAEKNGWDHADPFQEDQQGQQDTPGQPNRVAFSHPSPEARTSNEADSHSRNDSNSSGEQKLERVHTYEKIKHAAEDVAPGLVEKIRTAKELLHLHSVKATGPTNFFNPTNIRMKVHFRHNSDENTDFGMRDSKDMDLLWRSRDNRKGRNSIAVPEMPTEETPFLPMRYTPRLSTKFADIRKNLWKMCTTFAYWDMAFWSGWSYTIGSALFVTNGVLAWGPKAFGEDFESAQTEGYGPSLTFFIGALFYQIGAVTAYLEAVNDGSFHGAAMRKLLEGHDDDNKKLLDDKIHHFFSHMNPAHRHREEVYQDPRVNLNPEAGWNTKEARNLRPGSIYPRDKHPAPRRGAVDMGGEESEGSGYMVWRWWPTWKALRTHHVYEIGYTACAIQLFGVTLYGVTAIVILPGILSSLNWWQTLGAYWCPQIVAALCFLTASIMFQLETQENWWKPEPKVLGWWIGIWSVVGSVGFELCACFGTAAAVREWHWAEYQSDLSSMWGSAAYLTGSFLQWYEALNKNPLEELLNEPGEMKSHQIHPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USJ7</accession>
    <name>A0A9Q8USJ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765239.1">
        <property type="nucleotide sequence ID" value="XM_047910153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USJ7"/>
    <dbReference type="GeneID" id="71990883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11005"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="62" mass="7005" checksum="C9AE2E3276560E17" modified="2023-09-13" version="1">MWTNVPPARYDDVIMGDFSWTSLRDEVDIDQDSYCSDPDYNWPGSLASSERKDARSGTSHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USU9</accession>
    <name>A0A9Q8USU9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridine kinase</fullName>
            <ecNumber evidence="5">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 5">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 5">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="5"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765528.1">
        <property type="nucleotide sequence ID" value="XM_047910783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USU9"/>
    <dbReference type="GeneID" id="71991513"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11635"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002070">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="58"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="491" mass="55158" checksum="1F93C670A486DBE8" modified="2023-09-13" version="1">MSLPKLELPTSSYDQLHVGGRSAGFSERVSDSRDAPDSDSSRGSSVAPKAHYSPPWANTSIIGIAGSSGSGKTSLSLAIIRELSLPWVVILSMDSFYKPLTPEQSGQAFRNEYDFDAPEAIDFDFLVEKLRDIKTGKKADIPIYSFEKHARLDKTNTIYSPHVLVLEGIFALHDERVMDLLDLKIFTEADADLCLSRRLLRDVRERGRDIEGCIKQWFSFVKPNFHKFVEPQRNVADIIVPRGIENKVAISMVCDRVHKTLDHKSQMHRIELKRLGKVAEDAPLSHNVVEMEQTNQVRGINTMLMDPSLIREEFIFYFDRLVVMLVEQAFTSGLCYKEREVETPVPGRKYEGLAFDGEVSAVVVLRGGSCLETGLKRVIPDCRIGRMLIQSNPRTTEPELHYYKMAPDVASHKRVLVLDPQMSSGGAALMAVRVLLDHGVEESSIVFVTYSAGRNGLQRLMSVFPGIRAVVCRIVEGDIEVRWVEQRYLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTJ1</accession>
    <name>A0A9Q8UTJ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766365.1">
        <property type="nucleotide sequence ID" value="XM_047908479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTJ1"/>
    <dbReference type="GeneID" id="71989209"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09331"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="12058" checksum="3B5D95737B8A4D54" modified="2023-09-13" version="1">MVNVPKTRRTYCKGKDCKKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTQCKTKAQLALKRCKHFELGGDKKTKGAALVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTJ8</accession>
    <name>A0A9Q8UTJ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTJ8"/>
    <dbReference type="GeneID" id="71989397"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09519"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF14">
        <property type="entry name" value="PAF ACETYLHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
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    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040261951" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="414" mass="45455" checksum="F66D10121231A87B" modified="2023-09-13" version="1">MLTLAVACLIVLCAWYEYVAGAYSQVPLPTEPLPFRTTTFDHFELVDTRRVDPYFGGPRKLMLSLFYPCSGNHSIACDLVIRRYLPRTTAEHLDPLLRSLDILDMLDVWDLEFVEACLEPPEHDMRANYPIVLFSHGLNSSRLLSSDQAQRLAMKGFAVITIDHPGTARVVTWLNGSTSLSADFGTNTMVDQAVRVRSEDISFVLDQLEDIDSDLNALFPYRIPGDPSKTSPNGSSVALLGHSLGGATGLRNAFDDGRLAGIANLDGYPFGFNTTGTTLPFEPVFSLPSSVSKVPTLLFNVPQQIRSTAFTELYHRLPVGKRLQLSLRGAGHWTFTDLPFIIARRNGSDKLPGRLGPGAEENLGTINGIVAMNATVYHLAAFFDVVLKGKKWSSLLAPDATYPEVSVARPRPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU18</accession>
    <name>A0A9Q8UU18_PASFU</name>
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        </submittedName>
    </protein>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU18"/>
    <dbReference type="GeneID" id="71989283"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="26082" checksum="7523F10D7D43028B" modified="2023-09-13" version="1">MRGEIYVKDDAESPSGQTLVNGNAGHTRANGVPRQALVNGDASHTLVNENTGHTRVNGDAGHMRVNGIPGQTRSIPVPRRANGVNRLDHSQQAPPRQASPVVWDPRWEWEDMWAALKAMSRHYGSYHEIPEDIILDLPWIAFLLWSDAMKRREEVYARMEVIDAITKYGGHDQIPNHAVAQMTSMARAIYRHMMAFFDDPTRFSFRRNMLETIFPPLTNPRDRFPRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU94</accession>
    <name>A0A9Q8UU94_PASFU</name>
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            <fullName evidence="3">Cupin</fullName>
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    <organism evidence="1 2">
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UU94"/>
    <dbReference type="GeneID" id="71991598"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="39546" checksum="45BB40671D7AA43E" modified="2023-09-13" version="1">MAIQSTEVLISSNGIAEDIAFWTSDELGFRMDQIYPADDPAVATLSGHGLRLRLDKAATTHPGTIRLLCDHVPPERKTLTSPSGTTVDFVSADIEFPQPPTQHAFRVGHLADDAPWIVGRAGMQYRDLIPSRLGGAIIASHIRIPDAGPVPDNVHYHAIGFQLIYCYSGWVRLVYEDQGLPFILHAGDCVIQPPRIRHRVLESSANLEVIEIGVPAEHITTLDWDMELPTPTRRPEREWDGQRFVHSLAKDAMWKSWRIPGFEARDTGIAAGTQGVASVCVVRPDKGSTDANVVTTHDSDILFTFVLTGSCSLRGVGYGDHTLQAGDAYTVPPGVETSLDALSADLTLLEVALPGDFVTTVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUS8</accession>
    <name>A0A9Q8UUS8_PASFU</name>
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    <organism evidence="1 2">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8UUS8"/>
    <dbReference type="GeneID" id="71992019"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12141"/>
    <dbReference type="OrthoDB" id="3905718at2759"/>
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        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="20663" checksum="31354AE3A205E901" modified="2023-09-13" version="1">MSRVIAGYTLKFAADASSQAHKYSANATGGSFLAPNNQYTPTTRCFLLELPAELRNRIYEFVLTVEPAADGRVYLKKRPTSKTDSTGSMVARHWHDPLEGRTRFSGKWVEETINFAPSNLSILQTCSQINDESCALFYSVNNIAVPIRGLVQGSYDRTILPPSKQFFRHTSDVRLTGITRLTILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUW4</accession>
    <name>A0A9Q8UUW4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_12991</name>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        </lineage>
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    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    <reference evidence="1" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767747.1">
        <property type="nucleotide sequence ID" value="XM_047912139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUW4"/>
    <dbReference type="GeneID" id="71992869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12991"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="65" mass="6990" checksum="E9FECFFE3703013E" modified="2023-09-13" version="1">MATKSSCMQTAPPGSNLTSVDQLLGHIKPAQENYTKALEMIKREPEECVLAAAHAYDTRSAKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV36</accession>
    <name>A0A9Q8UV36_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="9">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12947</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767942.1">
        <property type="nucleotide sequence ID" value="XM_047912095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV36"/>
    <dbReference type="GeneID" id="71992825"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12947"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000022">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="636"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="669" mass="73197" checksum="B84E9E30B9C4676E" modified="2023-09-13" version="1">MMRLNPSAGLFRPCRHEVDDPRFEAFLEAFQPCWCSGLMEVFVVPEATNSIAGHGNANEAGDFCDARVKLTINHENTPFCLCNKRNTPRTSTRTTPKELFRKQTARPQAVMSFGGQTPTIIVLKEGTDQSQGRGQIISNINACLAVQSTIKSTLGPYGGDLLLVDENGKTTITNDGATVMKLLDIVHPAARVLTDIARSQDAEVGDGTTSVVVLAGEVLKEIKESVEQGVSSQVIIKGLRRAGMMAVNKIGEIAVNTTENNQRDTLRKLAATAMSSKLIHRNADFFTKMVVDAVLSLDQDELNEKLIGIKKITGGALQDSLFVNGVAFKKTFSYAGFEQQPKSFKDPKIVCLNVELELKAEKDNAEVRVEQVSEYQAIVDAEWGIIYDKMEALYKTGAKVVLSKLPIGDLATQYFADRDVFCAGRVSSDDLDRVCRATGASVQSTCSDIQSHHLGTCATFEERQIGGERFNFFEGCPEAKTCTLVLRGGAEQFIAEVERSLHDAIMIVKRAIKNQSIVAGGGACEMEISAYLHSFADKNVPHKQQSIIKSFAKALEVIPRQLCDNAGFDATDILNRLRVEHRKGNKWAGVDFDHEGIRDNLEAFVWEPSLVKINAIQAAIEASCLILSVDETIKNQESQAPQAPTRGLPPGAAQRAMRGRGRGMPMRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV45</accession>
    <name>A0A9Q8UV45_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767838.1">
        <property type="nucleotide sequence ID" value="XM_047911923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV45"/>
    <dbReference type="GeneID" id="71992653"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12775"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="270" mass="29030" checksum="604A86DD1E3AE793" modified="2023-09-13" version="1">MPFATVNGHRIHYMDTKQQGATIIDNHLPIVMIHGLGSSQNYYVPVIGQPELQGHHCLALSTYGAAQSKSQGEKLTLEQLADDVVAMMDHVNIRKAIIAGHSMGGPMAFTIAAKYPDRVAGVVGIGPVNPSSVNPAVFQSRIETVTKDGMDPLANSVPQAATNAKSTPLHRAFIRELITNQDPKAYASHCEVIVNMKDAGFELIKAPALILAGDEDKSAPMEGCQYIHSHLGSQQKELKVLKGVGHWHCIEAPEQVAKEIAAFAFKVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV86</accession>
    <name>A0A9Q8UV86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        </location>
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        <location>
            <begin position="239"/>
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        </location>
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            <begin position="26"/>
            <end position="41"/>
        </location>
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        <location>
            <begin position="49"/>
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        </location>
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            <end position="84"/>
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            <begin position="94"/>
            <end position="111"/>
        </location>
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        <location>
            <begin position="112"/>
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        </location>
    </feature>
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            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
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        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="29786" checksum="1865D7A375A49747" modified="2023-09-13" version="1">MSNAPTLINLPPPPSDPVTPSEVPSRSGTPNSTTTSMSELSTVAIKDGHRGHLPHHSSHHHPGSSRESSGLSHQLDAERADRISRLAGLERVTTARNPQTPTSYAPGSSGITPGAAAPPQHPAATTYFDATGNPAMGRERSTVGSASATGSVGARTTWAGSEAGDRADYDKMSESQDMDMDTSSVGGMSEEGTGSLVAFGEGARTPARQSTISSPGGKAATPRDARMIDGMTYDQHVLDTTSGQVPGRGQEEAERIMRDNMDTTSADRMRRGQGPRDLGSFGFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="2" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992852"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12974"/>
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        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="531"/>
        </location>
    </feature>
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        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
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        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
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        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="58533" checksum="CEC448CCFA1B19CD" modified="2023-09-13" version="1">MASNEQIPGVIMYPGYIKYEEQWEVNEQMKAMEFQQPCSSMRSTYTPAPHSGSLDLVDEPRTTGTMWDRLIYPDPTNPVHCRPLSCLVAEDRLPDQFLTPGLSYPNLGVKYPEALKLCPALKQRVPWDVCTSACDVLRDQNRMAETADQISHLEFMGSVARHLKLTWKLGLTSVNEESPECMYSHSQPHHNVARPIHHASGPDEGPYEPPDESTESVHDSGTEMPPPPVPQKSKIVRLKTNAASKSQVPATATVAAPVAAPVAAPKSSSGSKKRSRQSGPNQSPPAQETDDSEPEALQDDDDGDYGTAPPPKKAKRSNTGSTSNTTAPDVPKRKAPAPPGLNSRDPEDLGCRFRETENWMPEEDDKLCLLRLDLGDVLSWNEISKIMGRAEACRQRTSKGKPLRLAYPAGLVPRMPTWSMEDTIQVYNWRQSGNLREWKDIGDALSPQRTVLECQMQYRQYRVLDEDHMRRVLALTPKGIPGSAVIQPSHSSSAGDHNEEASSGSGVSTPSTVPSSDKTEPEVGEWGDLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWL4</accession>
    <name>A0A9Q8UWL4_PASFU</name>
    <protein>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_14343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040502369" evidence="2">
        <location>
            <begin position="19"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
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        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="470" mass="53048" checksum="EB828C74485C4C3C" modified="2023-09-13" version="1">MKRVLPLLLATAATLTCAHPLYPEVSSAFNPGNHTGDGLTYAGIVQGRIPQVQDICMNAPQSQIPILLSELCVDVLKASLNMLKGWEEEYHEAMQIEWHKKGIWTTDDKRSHELAQASVLWYKVVNVVTRAVTAHFEHKDEIPDPETNIKMLTFLQNDIITLGQVRRQRPEMEYSPNDDEAGKDKTVLDQGDILASENPSRVENEEVEGPSEPEMVDHTSTIDGEEVHMYLPVCDQACQNATHFTSWFSMSTIAVHQACESGCYTTRCLSMTQNSLADLLGFNDYYNSHDPDSPDWQIHSTQRTAEELLMKIEKAVLMAQLEWATDNHASETGQMLIKIKDDLWQLRSQKHWPGQKVPSPPPDLSQQEGGRLTPESATPDPGQVKVIPTVPEQNTKMSTWSLVKMPLGLMSLLLLMAAVFQGLRASHVFEEKTDQRYELEQGMTERLREDDELLADASVWDRPWSELKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UX09</accession>
    <name>A0A9Q8UX09_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_14522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769743.1">
        <property type="nucleotide sequence ID" value="XM_047913670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UX09"/>
    <dbReference type="GeneID" id="71994400"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14522"/>
    <dbReference type="OrthoDB" id="3650812at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="40723" checksum="877FEC23B6F2F52D" modified="2023-09-13" version="1">MASKVLRTYARVLFEHQAYYLNSEASLDRATLIAKHPVFGPALRILSLFVEEVERDYDLEDETALTEKIDASHKRKMRGLGMPPSTNHEKRLRALDQRRVSWLEQERFRAEGKQNRALRQLMDQIILNGKEVEMALTDRDGCDVKPTRPNDCVMSGASSRSPGHHSAEPIEVIHRALRGSGILGHLVTSLSLDARDWCLPACIRSPNFDGLTYLGLELNTVRDYPVGHALAPGFQFDSEKDVVRPLLNAVVAAATRSLRHLAVYDVSFAKAGSMPPSSSRADVIWLLLNETMPLLESLELVGGHVKIQELIAFARRHSSLQQLDLAYLRVGGWHKDDLFSEEELQNLVGIDGQYTNLTHEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXR9</accession>
    <name>A0A1P8YXR9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_02699</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">0WU</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="10"/>
    <dbReference type="EMBL" id="KX943140">
        <property type="protein sequence ID" value="AQA29311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758426.1">
        <property type="nucleotide sequence ID" value="XM_047901847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXR9"/>
    <dbReference type="GeneID" id="71982577"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02699"/>
    <dbReference type="OMA" id="WDVKYYS"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041008303" description="Peroxidase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="12">
        <location>
            <begin position="48"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQA29311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO14060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="317" mass="33337" checksum="2E46641EDAAF01D0" modified="2017-04-12" version="1">MLSFGLIALQVLAAGALPDRFDTRDFQQPRQSEADVQEGGGGGGGGGCPAVWREIRANLWPRFAGCSRGASFAIRFAFHDAATTSKSTPFYAPAAGGADGSLLLNDEEAARADNDPLQAFRGNLTEVYTQYHASHNISAADLVQFAGNLGTRACAGGPLVRTWVGRKDNSAAAPPGLLPPGFGPGADADSLIGLFADKGISAQDLAALIGAHSVSQAFAQQINGIPAAGSQDSTPTVWDTVYYSEVLDSKNETGVFDFESDRNLAADGTTRPFFERYARSVRAWNADFVVAMEKLSLLGIPQADRARFVDCTSVIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXU7</accession>
    <name>A0A1P8YXU7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03396</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">0WU</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4 7"/>
    <dbReference type="EMBL" id="KX943167">
        <property type="protein sequence ID" value="AQA29338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757513.1">
        <property type="nucleotide sequence ID" value="XM_047902544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXU7"/>
    <dbReference type="GeneID" id="71983274"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03396"/>
    <dbReference type="OMA" id="GHLWAPD"/>
    <dbReference type="OrthoDB" id="195678at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18831">
        <property type="entry name" value="GH43_AnAbnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573474" description="Arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR026534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQA29338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="326" mass="34781" checksum="FA10CA25A2E5677F" modified="2017-04-12" version="1">MLYKSALLALGCLSGYVQAQYAKPGACTGVCVDTHDPSVIRRSSDGTYFRFSTGGLISIHTAPDITGPWTFACKMLSTNSKVTKHGNPGSDLWAPDVSLIGDTYYVYYSVSTFGTQNSGIGLATSKTMNCGSFTDVGSVGITSRDGSAYNAIDANLFNDGGVYRMTFGSFWNNLYQVPMANPPRGTSGISVQVAYDPAGDHKVEGPALIKNGKYYYLFFSAGQCCGFDTNPAPAGTEYHVKVCRSTSPNSGFVDNNGASCRSGGGTTILASHGNIYSGGGQSVYNDPKNGWIMVYHYVNTNIGYANDQKQFGWNKLSFSSGWPVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L573</accession>
    <name>A0A9Q8L573_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dehydrogenase citC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755373.1">
        <property type="nucleotide sequence ID" value="XM_047901243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L573"/>
    <dbReference type="GeneID" id="71981973"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02095"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="9"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="4">
        <location>
            <begin position="365"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="488" mass="54101" checksum="365A8ABA0D43B1DF" modified="2023-09-13" version="1">MSEPNEGLNGRRMDHPRGKCIVGSSAINLMALIYPSKSGLDAWAEMGNEGWDHESMAPYYRKFQMHVPPSEEIQEALGIDYLDSEFTGTSGPNKQSFPQVLNPLHKAWIDSWKTLQRHGNPVNGIGNGGFTAPSSVNIETGRRSFAGLEYYEPIKDRPNIRVIVDAHVERIVLEKGTASSATATGVIFHRHGQRNLAHTSKEVAPGVLQPSMLIYIVENLQDHLMAGPCFEVADGVATTDMMIRDPEAIKQAMKQYDESHSGPLSWGGGYNYGYTPLVDFITPQPREDLKALLDKHLPPTNSPNFKAEALHHAFIRKIIESPDEPSAAMLCVTCQHHPQRDRILEKLAITEPENYFTIYTQLSHPFSPGSIHITSPSFRTRLTLKTNYLSHPLDIEIFARHIMQCEKIAQTQPLASFLKPGGRRLPEGHDALSLEAAIEMARACAESNYHPSGTCAMMPEELGGVVNERLVVHGTRNLRVVDASVFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5K1</accession>
    <name>A0A9Q8L5K1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755583.1">
        <property type="nucleotide sequence ID" value="XM_047899313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5K1"/>
    <dbReference type="GeneID" id="71980043"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00165"/>
    <dbReference type="OrthoDB" id="10265871at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="503"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="66723" checksum="F9880492C3B3AA68" modified="2023-09-13" version="1">MRPILIGNVSGSTGDRLDGLKSMLSGSTKVDAITGDWLSEYNIGTRALQKASSGAASYEPGFLHSLRLGLSEYKSYPKQLKCVVNAGGGNPKELALRVQQLLSENDIQRTIAHVSGDDILERLESVNIQPLTSVGESFASFREDKGKILSANAYIGATGIQLALEHGADIVIAGRCTDASPVVGLCAWWHGWKSDDHDQLAGSLLAGHLIECGCYVCGGSFAGFQAMGPKHFDLSFPIAEISSDGSAIIQKQPGQNGMVTVDTVRTQFVYELQGTTYLNPDVVGDFTNVRFAQCGNDRVQVSGAKGLPAQATLKLALTAEAGYQAEFYIFVSGLQAKEKVESFKRMSLKMVDASVLKKLEFQVCGAEVYDPNSLNASMTTLRVFAQADDAKSLTRGRFLGPLLSNQLQGFPALTPILDYRTADPKPFVKLFTGLVPATSIVETCHMLAESSKGHEQVFSASKTSKVDRTNAARKIVRASPTSLAVEAYQPIADFGPTKRTAVGDLLYGRSGDKGANVNVGLFFPLAQETEEKWQWLRSWLSTTRLIELMGDDYHPALRIERCEFPLIRAVHFVVYDFLGSGVSSTSSVDALGKGFVEFIRAREVDVPAAFVPSKSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L611</accession>
    <name>A0A9Q8L611_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755881.1">
        <property type="nucleotide sequence ID" value="XM_047900546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L611"/>
    <dbReference type="GeneID" id="71981276"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01398"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="707" mass="76730" checksum="B943AB7FE90B13E5" modified="2023-09-13" version="1">MYNSNNYNFGPPAERNQYAPARNGESNAFNAYVGGTLGGGYGGGFGGGSASFPRGATMSSGLNPDVPRYQPPQRRLGDEEMIRPESSASNATFATQMPSFSTSQAPSRPPPTSRPFNGGMPSYTYGNNRSNDMMNGLGAGIGGMSLGSSTRQSREPPTSRDHVYSNHNGFNGNGGYDAHGSHAGNNGYSISRHDSVVSNKAPSATYLASQIMSGGTEDPFDRSLNRYDTPGKNIVPTLGPARFKDSKMFSIAETGNPDTADTAVTHVSSPQKPQGPPPIPDWLALALRGLCKPTLEEAFDALPLFELCRGVQPSAAGVVRIKDIPYQTTRQEMTAFVGRNAQILRMPEGSPYHAVHIMMERETGKTMDCFVEFSTPTEAGWVVRQFQRRVDSGRPPKVGDRVVEVTFSTQDELMAELFPRAKHVRWNNGQPVVDRTERKYYADKPAAGFQGFLHNEEFVSLGKHAGLSERSPFASKSPCRVYESMITTLQKYPWYAVEHVTIRERRAIYDCTINLIRILMENLRRANSRYSPLEPTPALLQELAVAALTCPGFSEKQKSNIVGLLHQSGFKAIADGQSINVRLGGNHELSSTWPFATLSIQPGTDMELVKFYAGLFRKATETSDSSSLHSRQIAKTSGAKGNPMGDIHINYGKNVHDLSLAEAAKKEFTKIEQLLGRVCKGANGGSGSKPSSTVGGSSSSGSRYSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L629</accession>
    <name>A0A9Q8L629_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF985 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755921.1">
        <property type="nucleotide sequence ID" value="XM_047900502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L629"/>
    <dbReference type="GeneID" id="71981232"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01354"/>
    <dbReference type="OMA" id="GFEFADH"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387:SF3">
        <property type="entry name" value="DUF985 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="RMLC-LIKE JELLY ROLL FOLD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF985" evidence="2">
        <location>
            <begin position="30"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="230" mass="25966" checksum="ED1437FDA0715F42" modified="2023-09-13" version="1">MSSSSIDPTLPPLKPSFQASDHKDESLSIQALIEHLDLQKHPGGGYFVETDCDSRTLTVPPWKDPSNTTPTHNASTTIHYLLTRHTPLGHFHRHRARTIHTLHRGRGRYVIMHADEVASPACPSGDSSSTSKDIPESERWVGKARIETFVVGQDVLKGERVQWIVEGGKYKTSYLLPDSDESRESEGLLISETVVPGFEFGDHDFLREERLKALVEERQAEEMGWMLRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L710</accession>
    <name>A0A9Q8L710_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756384.1">
        <property type="nucleotide sequence ID" value="XM_047899445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L710"/>
    <dbReference type="GeneID" id="71980175"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00297"/>
    <dbReference type="OrthoDB" id="5391053at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="52209" checksum="00799AEF8DDD4396" modified="2023-09-13" version="1">MKGKIGILTKAAKAGVVLLQPLHGVRSWRKTWSSKRRNAQAVEADVPSIEIAALAEPHGVAYQNVDHEHPQDSANENPTDDEPESQDVDASCRPGSTDALLIDEPHFDAPPTSGPVRQPKVQQTVGAWLAACPDPELAASFHAAVVSHRQIKGVEEEVKTQLEELIPSCQEFRAETQKLMGRIADAEAEDSDPESDNPRVEAMYERLEEVQQAHGSALAKQNEIRDHLREVYEGMRGEQFDLFDILEEALEVGKPVSAGVESDELEYDNGPVTDDPMQEVSDDHQKDLLYTFDLWHRELDDANYQLNNRHEAFNRQLEFERDQPHEVRLAKSEIDARHFHETQRMTRRFIEVEAAYDKAKAALIAAGMQPPGSDIESGFVDDVDDGYRTSFQQDEIDSVDPECVLRWLGGIPNCSPGDNLGVQVPKVDDWDSTEVEMWESRSMLAEGSNRRRIEKWRGVMGSVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L769</accession>
    <name>A0A9Q8L769_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755834.1">
        <property type="nucleotide sequence ID" value="XM_047900418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L769"/>
    <dbReference type="GeneID" id="71981148"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01270"/>
    <dbReference type="OMA" id="WEFIQFV"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="141"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="450" mass="52226" checksum="FEEC587CF4C32685" modified="2023-09-13" version="1">MALSGTGNRLQRSQKRRTRRNDQLCLRIMLSNGRFPVSLDLARQLSKAGHKVFCVDPMRYHVCKFSVATTQCKQVPAPHSNPLDYIEAVKYYAIKWEIDMILPIHEEIFFLAGSGEPEILTRLFAPSFEMLVRLHHKFEFSKMMRAAGLGVPEAYLCTSTNDVANLPLHKYAHGMALKPCFGRASTGLHHLKLDEPMPDDLIIDEHHQYVAQEWLVGQRYCSYSVVRNGQVEATGLYPVLETIDGHSSVYFQQKFHAGIYDYVRSFVSKIPAFSGQIAFDFIEDADGIWAIESNPRAASGIHLWSDTTHLARAITGSLPKEEIERPIRPPRRMLGHEPHFQVAAGMLMWKHERATLKVWANHMRRLMFTRDVILKWQDPLPTIAQPFLLSNYYRMCWREHMQLPDWFQQQLIWEPQDWEWNAMRMMLAKSSDEEDEYYDCVDSQEEHSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8K9</accession>
    <name>A0A9Q8L8K9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial 2-oxoglutarate/malate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00079</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757080.1">
        <property type="nucleotide sequence ID" value="XM_047899227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8K9"/>
    <dbReference type="GeneID" id="71979957"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00079"/>
    <dbReference type="OMA" id="TLWRGAI"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000009">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate/malate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="50"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="151"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="249"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO12714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="341" mass="36597" checksum="9702A77B3993A9CF" modified="2023-09-13" version="1">MASAVEAAKRKANEALNAAKVAAEDAPAAMQKASENPQKATQDFLHSPFMRTALPFVNGGAAGMVATSVIQPIDMIKVRLQLAGEGVKTGPKPTPITVTRDIIAAGKVMDLYTGLSAGLLRQAVYTTARLGFFDTFMKSLGARAEANGQKIGFKERAAAGLSAGGIAAFVGNPADLALIRMQSDGLKPKAERANYRGVGDALTRIAKNEGVARLWAGATPTVIRAMALNFGQLAFFSEAKSQLKDTSLGPRAQTLTASAIAGFFASFFSLPFDFIKTRLQKQSRKPDGTMPYKNFLDCAQKVIREEGPLRFYRGFTTYYTRIAPHAMVTLIVADYLNFITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8S2</accession>
    <name>A0A9Q8L8S2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylenetetrahydrofolate dehydrogenase [NAD(+)]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
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    </dbReference>
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        <location>
            <begin position="13"/>
            <end position="117"/>
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    </feature>
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        <location>
            <begin position="146"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="35046" checksum="873B9CDF38697BB9" modified="2023-09-13" version="1">MASSSSCKVVLANSIAKSLLSEVTAGIQKLDRAPRLHGFLANQDPAARMYADWSAKTCTENGVDFTLREVDAEDLEDHLREANTNDEIDGVIVYYPVFNPPRDRTLQWTVSLFKDVEGLSPQLISNMYQNIRYLDPPTNSMKSILPCTALAIIKILEHLQIYNTFLDYSKRLFGRRITVINRSEVVGRPLAALLANDGADVYSVDVTGVQQFSRGSGLKKQKHEVTDKEGWTLKDCLAISEVVISGVPGDKFKVPTEVVREGAVCINFSSEKNFTPDIKEKASIYVPAIGKVTIVVLMRNLLRLTQNRTQQNGTH</sequence>
</entry>
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    <accession>A0A9Q8L9R4</accession>
    <name>A0A9Q8L9R4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="UJO13447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757813.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9R4"/>
    <dbReference type="GeneID" id="71983383"/>
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    <dbReference type="OMA" id="YPQGQNA"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF10">
        <property type="entry name" value="RICH PROTEIN MS8, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05650)-RELATED"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="21920" checksum="4DF5F74496603E7F" modified="2023-09-13" version="1">MSGPYDNQSGYGQQGYGQQNYGQQNYGQQQQQYGNYDPNYPPQGQGYGGGYQQQGGYGQQPYQGYGAPPAPDYTGGQQQVGGGYPPQQGGFQHGGQPQYGQQQGYGGYDQQQPQQHYGQQQQPHNGSDPSNPYGYTRDPADPNNPQEGERGFMGAMAGGIGGGLLGHKAGHGIIGALAGAFLGSKGEDKLKDRHNKPNGGSSHGGKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9V3</accession>
    <name>A0A9Q8L9V3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrimidine 5-nucleotidase</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71982485"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="27177" checksum="33154805C59F6170" modified="2023-09-13" version="1">MVSNENANGDAPPRKVFFFDIDNCLYPKSYKIHDIMGELIDRYFQTHLSLSQEDAYELHQRYYKDYGLAIEGLVRHHKVDPLEYNAKVDDALPLEGIIKPNPKLRRLLEDIDRTKIKPWLFTNAYINHGRRVVKLLEVEDMFEGITYCDYSAEKLLCKPDPAMFAKAMREAGITDPSQCYFVDDSAINATGANAYGWKTVHLVEPDARPPPQPACDYQIEDLEELRSIFPEVFKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBL8</accession>
    <name>A0A9Q8LBL8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758746.1">
        <property type="nucleotide sequence ID" value="XM_047903008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBL8"/>
    <dbReference type="GeneID" id="71983738"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03860"/>
    <dbReference type="OMA" id="DDTVYAC"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="45653" checksum="D02493F04C083B87" modified="2023-09-13" version="1">MATEGKRDIVIIGGGIIGCTSAYYLTRHSKYDLSKHKITVLEASKIAGGASGKAGGLLALWAYPKSIVPLSYKLHKALSDEHGGEERWGYRTVHVGQVDCVGRNLPEKAEKDRLDGKDGEMDGRNGDTDKEHVSLQKRSKHALGKLRAAGIPAELDWVDADSLKGYDEMGDPTTTAQVHPYQFTTSMAQLAQEKGAEFHEDASVTSINYTPDNTAVESVTYTDKTTNTVHTLPATDIIIAAGPWTRSVYPSAPISALRAHSVTIKPSRPVSAYALFTQIKLPSPFTRGATPLNPSTQIATPEIYARPHNEVYACGDGDHLVPLPATSSEVQCDESRCQDIVDYVGSISDELRDGEVTARQACYLPSVEGSSAPLVGGTGVRGEVLACGHTCWGICNGPGTGKVVGEIVFEGKARSADVEGLDPRGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEL7</accession>
    <name>A0A9Q8LEL7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Werner syndrome ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04821</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760351.1">
        <property type="nucleotide sequence ID" value="XM_047903969.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71984699"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04821"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="5">
        <location>
            <begin position="1200"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="858"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1061"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1470"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="863"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1062"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1072"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1474"/>
            <end position="1484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1609" mass="178871" checksum="6A4B4B30FB9661B6" modified="2023-09-13" version="1">MSGGNGLLGMSFSAPIFADAAHRVRPGSVALACEGASAASPRLPSTRPIDQRWDRSRGIISSNARRTIARDHTWSPTHGIIFGNIPASTRYYATNPVFAKKKPLATDSAATTSTGTTASDHATKAGWAGDNVHRAPSMSMNQVEATQLRSKNSQLESDIKSRDNEIIQLKKHGDTQQDKIKQMQSDFEDKIKRMQSDFELQKRTLEEKRQAETSKLEKRRQAETSKLRAELYAQTKFLADAEPSAQNIENQRAIARDETRRQVEAVMRWQHEIQIKELKESYAQQIATAVENSQVLTEARNQNALLAAQHEQERVRHREAMEKVQAEVKSATKEIAEHKHLSSYFQRQYSARQSRAKTDRDSYITYRNIFDDVHDAAHDTMTKLLFLARLLQSEARLWRRSASTFQNTKHLHLFRQTSKHNVIRKSINNFLEERSAHAELGAGNIIQLATQLRADAQAFKGPAHMSRKLTRLLHYDEEHTAFDLVDAAFHIATVLPFRQRRKECDGRISQIQAEVSNSEQSGQTVDPALRQELVVLRDRRAATIRLLSLFELIRRMKAYEALLHDTPVEKAVFLRTADAFEEFSQVQDMYLGLFERLQASSNESRIDQKDRMDLRRKFRYEETKANTALDELRVQARNRCVLEQELDQLTDTEQAEADREIKRRIERLVGQQNDLIDQLLPSMRSIGRQTRASLMRASSMDDRKAKLPGGVSAAKSTRLIPLTKLETALRTPLKRRTPEQALMIAEKTLGTKQRSFMREISREALESVADDQAQDLHGLSRRIARLKPRVHADNRRSLKLWKELEERYRQRRKAVASLLNREPGSVEVFDATITAIASNIATLKIELKAGVIAAGAPGSEGSSNGGSNNGGSSNGGSSNGDSSNGVSDVKRSESDGTPAANAIAVEPEVRIESVKPPASHAEGDSGSAQGPTASPAAPGSTNTNRTWTIAPAKKSRRERFPVRKQTTDNTSMDGLIAKLGAKAANVSGGASADALSGGLKLKPTAPKRSQHSLFASPSFSVRAVHKSTAFSRRTFTAAASDADSLSHLQEADLDALDEAFSTMPSLPTDPTTPHEEMIRSTHESAPVARSQGAMPPTAQSTPAPGDTLEDEASGYSPGIAPSVESPGSVAPDSSPAESNDVDVELTYNIPAQDFRAAIMASPNSSAAFWSHRLYRGTDGKQPAVMYCKSFEVAERQARLFTNENVLGFDLEWEPQTSIKTGHIKRNVSLIQIAAEDKIALFQIALFKGDTAEELMPPTLKAILESADVVKAGVNVVGDARRVRELLNIDMKGVFELSHMYRVVKYSEQERKNVSFKLVSLASQVQDILMLPLKKDDNRVSAWSRELNTQQTDYAASDAYAGFRLYHKLDEMRKSMDPMPPRPGFLEQELPLTLGDGTEVYKSSWKASGRKTAATSKGVDVEEEEDEFFDAIEEQNANDLTAKMESLDIAGDDGATTSTVTYPTLPQLDTEQPAEDANASPAAEAPQDEGPQPRAEATRQSARPDTTELKAADAWVTDWRFSLPPDWTVSARSFELRAYHLWHHQGFALKEVAAICREPPLALTTVASYVMQALKEENLPYDPERVRDPRDILPTSVHRRYQKIFDRIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF34</accession>
    <name>A0A9Q8LF34_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04662</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760752.1">
        <property type="nucleotide sequence ID" value="XM_047903810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF34"/>
    <dbReference type="GeneID" id="71984540"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04662"/>
    <dbReference type="OrthoDB" id="5561659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF8">
        <property type="entry name" value="PROTEIN ARTEMIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="633"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="808"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="908" mass="101959" checksum="21B09D3DAF765710" modified="2023-09-13" version="1">MSTFDGNVAELPDIRIDRFTRSESLRPPLALFLSHVHTDHLVGLETCKSPFIYCSPATREILLRLEKYPHRMNFAKGILESRKQTYKTIGKLLKPIPLETPTTLELAPGRSIRVTLFDANHCVGAVMFLIEDENKAILYTGDIRSELWWVNSLIRNPLLLPYVAAKDGPPLKRLDTIYLDTTFASKKDHYRQFPTKASGVMELLRQVSRYPADTLFYFDAWTFGYEEVWQALSIFLGSQIHVDDYRYELYKSLFKNDSMPAPEAFKLIGAKCGNHIQEGCLSTQQHRIHSCEKGTGCSVWNKNFVRITPIISRHEGRDMPELGAGGGHGDLNQHHALDVDNEAVVSAMMQICAVKLPDQPSLLDSIEQMLTTAMNDPGSSLVLDAVDISQSGDVFDDLDGLPLESIPAALAKRVTRLKQQAKGPPRSDSSTIQGLPKQITFPYSRHSSFGELCHLIEAFMPKDILPCTVEKNWKPTQSMGYLFGHLYDQAPVFRHDQVMLQRGDVNTAVTSRPVSRNRYSQNTQDYDRVLSQLRSREVSPPQASRRRSAQKAGFEQEDDTGKRKKLTSRPEPSVELCQHSPLRGIEVSSGPSGHEINDAGLAGPRSSQGDMWLPQDLNHYSPTTKRAEPASKRRLYIGGLANHTTETELKDFFKDFAVSHIDIPTDPQTKGPARYAFATMPTISEAERAVNELAGKTVMNRKVKVELARRGQKDASTGQASKRRKSSTDVTRATSVDHTPAERVQDLQTVHKEWTHHPLIVDERSSPSRQINSWRRQTAEARRKSSVGEDLFSWDSLEAPRRVSRTSFRRQSSIRESPHIQPEGYGRLSPITPPAVQVDAEADIAANLDGRDAESVMKTELDEVEQEAELRLALQHEAYHAALGEGELKWSEIGLVSVHGHQVKEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFZ5</accession>
    <name>A0A9Q8LFZ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761156.1">
        <property type="nucleotide sequence ID" value="XM_047903244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFZ5"/>
    <dbReference type="GeneID" id="71983974"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04096"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21352" checksum="5A23DB46EFF87315" modified="2023-09-13" version="1">MAQAQVLPSSHFTLSGHPSVASRDDSWPGATTATTQEVSVLEIEVHSPQTTANLLEASSSAIISDYFTPNHNEWHNAKAHCASNYEFIDVNDHAACLPHSTDLETFMSNMEAQRKAYTTFVMTSHNYTAFVDEELGLVVMTFIFRGHNTVDDQATVRETTDRLMRRRREDWTWEFYLHLHGGRSGALYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG83</accession>
    <name>A0A9Q8LG83_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Non-canonical non-ribosomal peptide synthetase FUB8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761248.1">
        <property type="nucleotide sequence ID" value="XM_047904513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG83"/>
    <dbReference type="GeneID" id="71985243"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05365"/>
    <dbReference type="OMA" id="DYVYLAH"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="558" mass="62677" checksum="F083E732FFE754E6" modified="2023-09-13" version="1">MDDIPSEKRLPASVISHRANSTPDMVVVLLPKGQALEDDFFGLTYRRLNYAVDNVAFWLDSVLSQGKKVGYESESQWSTIVYAGSNDDRYVLLLYAVGKTNRKAGSLLFPSSGGRWLTGTQPMVITLPTNPKDSLIKLLNAQGVKTALASRVPISPVKDAMDHILGGQVLDMPPLSTFLDAIPPSTYPYDREWSKTRNDTWLVMQSSGTTGDPKPVTQTKTFIDAYADMIAARNKGDNLQLAYPVVLRDCHAPLLWPLSWGAGIFAAGMFPLVSITITTLIPPTMPSPMTPEYVKDVMRLELAKEPSALEGSKNYDWVSYAGAPLDNDTGDLIAKHTRIQSIIASTEAGIYPLLLNSPSDCKYHRLHPTLHGWLLVHFQDELYELCIRKAGENEWRPAFTMDKRNPDLLQVFHTKDLCRIVPGRQGFWDFCGRTDDFVELVTDEVQWDKYRTHHRSPSRRQSMPALHLSSDEVIERIWPAIEAANKTLIEQAELGKKVVLITREDAPTARLAKGTINRRATLKVYEGEIEELYWKYIQSALLDSTKTPGLVNRVRPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGS5</accession>
    <name>A0A9Q8LGS5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor pbcR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761492.1">
        <property type="nucleotide sequence ID" value="XM_047903229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGS5"/>
    <dbReference type="GeneID" id="71983959"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04081"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="225"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="791"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="833"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="928" mass="102597" checksum="C4E1443EFB0A9F31" modified="2023-09-13" version="1">MSGQQQHPQIDPRLRLGGDSTPSAPPPPLKYERPPPVPQTYAPSPPQPYYHYPTPQGHTPQQPTTGAPSTGSASNQASPAAPPPPGAYHIPHDANANNSHDDGEGGIGEDPKRPRACEACRGLKVRCDQDPAHPELPCRRCQKAGRQCIITAPSRKRQKKADSRVAELEKKLDALTAVLQQQQQTGHVPQPQQQYAPSPRAGPAPPADMMQGRQQPANIQQALQQYHQNAADSPSARSGSSGMQPPQKRRRTEEGATDTQESADNANAGRMGRYQANQPVQDDSMKRLQQMSDSWGPYADSMRYLIHRSPEEFMNRINTLVNPEIGVTIFNRYLHKLAPQMPAVVFHPDTTAEQILKEKPILYVCILSASSAGTLHPDVTKQLSREAIRAIADCVVCNGAKSLELIQAMQVLALWYKPPEKAEQTNFYQIIHMAAVMAIDIGLGKRFNATKARRGFGGPHAEFAPGPQMQLPQNSDTIEARRAWLSCYFLCACASMVLRRPNLVRWSHYMKECVDILGSSPEALPSDKLFCQHIKIQHICEEIGLQFLMDDNTATISITDPKVTYQLNVLENELKTWSDNIPAELKQHPGLCFFEHVANLYLHEIALHFNHNIEDFRLPFTEESLKAVNNSSETLTQHQMAALDACRKAANGILDTMLSYNLDTVKALPMLIFFVRCTYALVILIKMHVAITTPGSEISKIMAPEDVRVDHYIDSLMGMFGSVANQQEFRPHPKILRILTVLKDWFGRHKENIAAQARGEPLPHPPTWNGQDLMQQADRLGQTPLHMLSQVATANRQSDQQPQQGEDQGRGEGWTFNTPFPVDYSQRPAPGHPDSRFPVHQEKQAQQQQATYPPPPDNGQAYAAGGPDQYGIDGTIPDYLWGSGFEQAMGINLGSMDELNGSGMDGLFLGGGMGPFNFNGDPGAASGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGW8</accession>
    <name>A0A9Q8LGW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760784.1">
        <property type="nucleotide sequence ID" value="XM_047904119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGW8"/>
    <dbReference type="GeneID" id="71984849"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04971"/>
    <dbReference type="OMA" id="HEPAIEV"/>
    <dbReference type="OrthoDB" id="3643933at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="25582" checksum="3154DCEE4B6CBECF" modified="2023-09-13" version="1">MAPRKPQSWAKVRAAGIAANKVKNASATPQSAWTALIHQNNEHAGNLRALINRKEEEALFGDDDEEEDAGDDVEGEKKKKGKKATEKSKPKPQKITKSTKPKKGQTSKPARTTRSSKRKPIIEDDACEPEIEFWRPYGGETSKDPGATSCLGLARLSTWQYPKFEEAMKGLLDVYAAGAELETEEWKHGGESVTDVLARFNSEEQATLIKDQIEGEMVNGRKVQVRFVDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH76</accession>
    <name>A0A9Q8LH76_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05983</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="7"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761758.1">
        <property type="nucleotide sequence ID" value="XM_047905131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH76"/>
    <dbReference type="GeneID" id="71985861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05983"/>
    <dbReference type="OMA" id="DPLWDET"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF169">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="307"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="592" mass="65410" checksum="7777421F5D9E2771" modified="2023-09-13" version="1">MSGLSDRLSKLNPFGKAKTDVEDLGEEMQPDSMAGGGHSTRPTKITKEQLRVSHAVKKFLVDHKIFNANDAALDNDATSSALKELLDRPHVNVPPAVLDRSHPLTEYFISSSHNTYLLAHQLYGTSSAEAYESALRTGSRCVEIDAWDNDDDKDEPKVTHGYTLASHIPFRSVCETIRDVIDTEAAAPQLGSGYKAAPVLLSLENHCNAHGQSRLVDIMREVWGDRLLSEAVRNEGTREQAGTGEHVTLAELGSKIGVIVEFHLPDGDGESSDSSSDEDEDEQVRLDHQKYREQKKQNPAMGIVPELAELGVYAQSVKPRNNSWFEEDLQDGPHHHLINVSESGLLKLMPAHSDKISKHNAKHLMRVFPKGTRISSKNLSPVPFWGIGAQICALNWQTFDHSMQLNEALFAGSDGYVLKPAALRADGSGIVDSGKKKVLKLHIAGATDLPIPEDREADEIRPYVTCTLVHPDDISGDHPKEKTGVYKQHKLQLLHKGENPPPTDPIWNETLKWTYADNELAFLRILIKSDDRFARNPVFVVSAVRLMYAAPGWSFIRMLDLKGRETHCTLLVKFEIVDASSGRFGAGIAGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHK4</accession>
    <name>A0A9Q8LHK4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761129.1">
        <property type="nucleotide sequence ID" value="XM_047904260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHK4"/>
    <dbReference type="GeneID" id="71984990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05112"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="18296" checksum="1318673F48E5A299" modified="2023-09-13" version="1">MLVAMRLQYTIEKLKGRCLRVADFRRHLEGPVCLNPHWLHWASDNAWSEIETEGLKKEKFDEKLEARVDFVVDSAELEYVTVLASEGGYSAKDIDQIVRSRGFSVSVMQDRFERQYVKALAAHVSDRMTKEELAQAKGDLPDQFMGERYQSSHAEASNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN4</accession>
    <name>A0A9Q8LHN4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type transporter cicA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761174.1">
        <property type="nucleotide sequence ID" value="XM_047903724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN4"/>
    <dbReference type="GeneID" id="71984454"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04576"/>
    <dbReference type="OMA" id="KEQHIAN"/>
    <dbReference type="OrthoDB" id="5423067at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="123"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="250" mass="27648" checksum="D53F375F2722617A" modified="2023-09-13" version="1">MAISARSSVDVRARVLPRSWLRLINLLKKRNLPPVPDQRGISGEYKANFLSTLSFQWMQPLLVTGYQRPLELNDIWEVNPKREVVVLADRSKAALAKRKARNTPSKLDLLVWAIYDTFPVELIIGAISTFIAWCLQVLTPFVLRDLIQFVQEAYNATSSGSPPPNIGRGIGLAVGIACMQSLQSLCTNQFFYRGMMLGGQARSVLIACIFEKALKLSGRAETAHGNGGEGWTNARVINLMSTDTSRIDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHR8</accession>
    <name>A0A9Q8LHR8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase puf</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762086.1">
        <property type="nucleotide sequence ID" value="XM_047904804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71985534"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05656"/>
    <dbReference type="OMA" id="GHYWSYT"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="1430"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1824"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2375" mass="266370" checksum="30D234D021980D15" modified="2023-09-13" version="1">MPAANADYVRDAVADANPDLTRKRQRLSEEADETSPLSTKDDILIEEVPMEEDGSSLANAIELHDDLDGGPLAPFSDIFLLSPANDMTAPQQIEWLRGHLATPNTHMDPAFFAVLATALGNHVTQAQALPDLGRTKYIDEQDFFDKLGEVCFRILARHTLFEKHILEDKRCKAEMLQHINDFMQNINDMCLNVLEILPSLMESISTRRDSGSIREGPQRNSLLWFIRILGQSLAGYNAGVFSHFKDFDFRPVASRKIREQQFLGFQGATDRLVTLLRKLTKYNKQLIDSAWDEQAWEAVSAILHVQDKLQVDKPDHIRAVLKTLHEDVLPVTCNRKKQALPVRLHELSISLSEKLLSQLLASADTEATIDIYTTYTRSDDDALFPQRTDGGALVQQLVDLSDSDVEVQRSLMSTASWLQQMNRLLHSDIMDFCNYGISELNTRLPKIYTQYRDSPQGLEHPVLVYIARFLRCHEVIRFIFGPNSHSSLINYSRDIVGFLAAINNYTNQETDVIWQACTESVEVEKVKASWSVLHGISGLLDIDHLLYLVEQFSLTARSKLSNDMIAALSDLFSTVSKTANGPLEGENRLKTAFVSIDLMMGLDATSEDPVSKQLRRVATHELLRFMGPDYTTGDRHQIFARCIQRYGASGGDATAAVTILNSMLSKITLSPDDTQDLLGMLSVPTAIKELGHFVEDRRALEDRNSTRLSIIARLIMILHLMTLAHETWAVEIAQLLFDIVVGDLALDNTARDLAWTYLSNVVKGTPQPSRVVRLLFKHFISNLASEVSLTHTTPRLVALLGASLGSPKDEYEMLGSPVWAKLVHCAESSGDDRVRQAATDTIRGILCNPDVPLPKGIRPVELQSKFTERQIERVLATSGKPGAASQQLACRQLDLLDAVLQASAKYPARVKTNKNSKLDLDPNSAENKVHFLIEVYWGGKNEPEQYHSSRSKTTKLRALADRLPALTGAYEHRLILGGKLVDLTKQADETLSSIGLQSSGVLQICPKYTIQSDINRLMKPVGTVEQTIMSHYKRIEALLVGTSEIARRTYDLLKQIRPPDETRDRVTSPQTELNEICPISSKWRIMMTAHVLKTHLLDFANIGVVDQTFFMRGTRILIAVVMAWNQMLDPQITTTVLDCLVCFLQERAETTVDVKITQEPDRLVTRMLDMCFRAVELHTKQSDLAEQVYKALLHAFQQQPEIWDSFVADSRTVDLHRQLLLSTNAELLGKVSTMIETFCKESFATSEGGASFYLKVLLGLVPDALSPQGRNAAFFQLATNILHADTTLPADEEGARDTMQELVTALWQYRHTETPNFPQKDAAMAGLLQLLLESIQVVRSAKKPLALEGFALQVFTQLLFPNKDGSCWQALLDEQSRSVAFRLVKATCESEEDIYGIIDRAFSALQETGNDPAATYPGRDKFLRAATEPSGLPNLRNTCYMNSLLQQLFANTKFRKFIFSIPLPGGSQETVLAAVSRLFANMQDGYFTSIDVAHLAKLLDIDVWIQEDVHTFYENFLSRLEADMPSADYKAQLARFYTGNLVSQVKGACGHVSSRLEEFVDIPIVVTNQKDLASSLEAYIQGEQMEGQNRYRCSACDPSTDGRLVDAMKRSCIEDLPDNVTFCLKRFSFEAMFGGDASKENGRFEFPQSIDLGKYTRAQLEDPEAKKDEDIFELVGVIVHWGTLTSGHYWSYTLVRNTASPDSRKWLRLNDSTADTVKNGLSEVQEECFGGGLGFDGKPRQDSAYVLFYQRKTSLEEQVAIATPVSDYSCMDPMPARVSLPPALEEELCKNNTWHQRIAQLFDDDFASFLAWAMENFGQYTTWGSSPSDTSISSREGPTGATANDLVNSSPDFRVIQAMNLLVATYYKRVVVCQPVSWKKLNTLVPSLKKLVSEQAIFAGYFLNQIIDDTPWFSKMILHEKRIVRTTTYELVVACLTALKQCDTTAYQSGLRQAVNIHSNMIHSNLSLGVEADYINFAIDLANLGAEEMAFILGEGYYTWAVHLLMLPANIRRQKHNPGLWHHFTTHPNMVSALYDFVHIVISAQLELEKARKRAIGSSDSGVSLYTDELDMLVKHGNPEVFYWMYAARHANKPNDWTTSSPGRLLSLLCEALPPQTMDMVESSLLGFIAQEEESFPAVMSMVLHYLSCDLPLERALPACNALGTTLIEWAESEEEFLNRIKDAYSLASVAILQSTKIWLRNMLTMHSKGTVRRGTRDFLMQEIFTGPAISDDEDCDAARAQFAMNMVTENCGVLKQAYSKEYARARYEPTIAIGRTAVQHLHDLCDEATKLRADAEEEEEDADDPVSMKLQIWIDEAQRAWTAWAQLEEDVLGDWSLEDEIVLRGNTRAESVEVSDGYYTSDYDEDMEDGSPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHV4</accession>
    <name>A0A9Q8LHV4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Woronin body major protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-5A family. Hex1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO17749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHV4"/>
    <dbReference type="GeneID" id="71986196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06318"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140266">
        <property type="term" value="C:Woronin body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04469">
        <property type="entry name" value="S1_Hex1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000033">
        <property type="entry name" value="Woronin body major protein HEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037318">
        <property type="entry name" value="Hex1_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
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        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A-like N-terminal" evidence="4">
        <location>
            <begin position="80"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="3">
        <location>
            <begin position="153"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00061629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="25768" checksum="E49140E94E8ED089" modified="2023-09-13" version="1">MGYYDDEGHYHSFRHGLHKAADRIIHPFESHDRRHHHHHSEGRVEHEEDVVVKDREVTMSAPRYDGGERSYRAERRGVPNTITIPCHHIRIGDLLILQGRPCQVIRITTSAQTGQHRYLGVDLFTKQLHEESSFVSNPSPSVVVQNMIGPIFKQYRVLDIRDDGRVVAMTETGDVKQGLPVLDQSSLLNRLQDSFNNGRGSVRVLVISDEGRELAVDYKVVHGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIB5</accession>
    <name>A0A9Q8LIB5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase BOT5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762370.1">
        <property type="nucleotide sequence ID" value="XM_047905308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIB5"/>
    <dbReference type="GeneID" id="71986038"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06160"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF310">
        <property type="entry name" value="FATTY ALCOHOL:CAFFEOYL-COA ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="473" mass="53354" checksum="C8E931C257F7A45C" modified="2023-09-13" version="1">MEDEIYPLHSLDDTKSNRQFVSWLLRFNDVLNAEVLHDALCRLLGQTTWRKLGGRLKQRTDAKLEIHVPRAYTVERPAVAYHHQSISTTNIDDHAPARCLPRGFNSSRMKADVLDMGQCPFIWPTVAPSSVEETIDRDMPLLSIRITTFKDATLVSLSWPHVVMDAMGARTLLHCWSLVLLGKDREVPVISGTNDDVLLQEAQQVDSNEVFALEHKRLTGAGELKWGTRSLWDSKFNEKHDFRAICMTPRTMERLKERVRGEIAHAPNSTAFASEHDVLVAWITRAIALSRPKSARPMTVVSLYDIRCRLPTLLQTTSVYVQNMSLVTFTFLSSQATTGSLGSIAVENRRHFAEQTTEAQTLKLLRATQRDIKTQGAPKLLFGEWNAEPLLINNLTKAGIVQSCNFGPAVIRQGESTERRNNPIGTMTSYSIHDRPAGSANFLWVLGKDHGQNYYIMAKLRPKVWQSLEKDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIZ9</accession>
    <name>A0A9Q8LIZ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05683</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762748.1">
        <property type="nucleotide sequence ID" value="XM_047904831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIZ9"/>
    <dbReference type="GeneID" id="71985561"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05683"/>
    <dbReference type="OMA" id="DEMAYEN"/>
    <dbReference type="OrthoDB" id="3648505at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="239" mass="26091" checksum="87AB425A1F770542" modified="2023-09-13" version="1">MASAPGDSTNVTPMATTSVLRLHVPPDDESGDPTEMHISADPFNDDTHWVISPISKQLGLPVKVAIYSSEDAQQENETARLLFLDAEIGSPSFALSTCDPCMGPVIVLRCDGQDIDATTRLTLTGKTQEYIHDVRDRFDDLKSGEQTIEEFYAHARARFTRESAAKLYRDLMDGIAGYLNPFKAITAGGIRFCAGCGAIKATSGRALLVCGRCGVGRYCSRECQKQEWQVHKSGCKKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2P9</accession>
    <name>A0A9Q8P2P9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755345.1">
        <property type="nucleotide sequence ID" value="XM_047900871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2P9"/>
    <dbReference type="GeneID" id="71981601"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01723"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="12954" checksum="F15C4130E8100F93" modified="2023-09-13" version="1">MCGNVTWCPNEATTAIEVQGDPAPMMISASATSACAIPTSADLRQCTKIAAGPVVITEASGVGDIGTAVARRQDAAETGSMASGGAVSCICGSSMTREVWPVTCGSQTWCPNEATSAVEVTGTPAPATLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3C8</accession>
    <name>A0A9Q8P3C8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_01613</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756169.1">
        <property type="nucleotide sequence ID" value="XM_047900761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3C8"/>
    <dbReference type="GeneID" id="71981491"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01613"/>
    <dbReference type="OMA" id="RFWTSQP"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001301">
        <property type="entry name" value="Structural maintenance of chromosomes 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="12">
        <location>
            <begin position="93"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="708"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="844"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="928"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1144" mass="130738" checksum="4725644DB5665A47" modified="2023-09-13" version="1">MSRAVTPQRRGREQDAESEGMYASGSGTQSSKRRRVEDDVATEDGDGDADTDEDEPSERPLLPDSYRRSPKNKGRARDVPGGHGQQEHKPGSIVRVTLRDFVTYTNAEFHPGPNLNMVIGPNGTGKSTLVCAICIGLGWSTVHLGRAKDITEFVKHGMKEATIEIELKADPQRHTTNPVITHTINRDGGRKSGPSKSLWQIDGKKSNAKEVQRLARSFHIQVDNLCQFLPQDRVVEFAALSPVELLVQTQRAAAPEQMSKWHDQLKSMGKEQRLKLVEQENITQQLKSMENRQRMQQADVERLRERTELQDQLHLLQRMQPFADYAKLQSQYKQARKEWSVADKELRHLQRRMEPNVRAVDTKQAYRDHLTNVVASRARLLARSENKADQLVQKVDDKAEAIKGLEQEIDAEKAGRKKSSETINKYQRLVRSIQHERENPPPDFDPVKMNEEIKSIKDEVRRLDTEINNSVNTQRDLGHQAQQRTQIIEQETANRLHLQSQVGRQESKLESASSDAAKAWKWIQENKDKFAGEVYAPPMISCSVTDARYADAVEAIIGQGELMAFTVTSQADFRVLEEQVYRRMHLTHVNIRTAGQLLTTFSAPFSQEELRQYGLHHWLLDLIEGPDPVLAMLCDNTAIHQTAYGERDITNNQLEAIKQTAIGSLVAGRQSFRVTRRRDLGDHVVSTRVSTINSSKLLTDAPVDTHEEQEIKRRIGEAESEKEEIAKEIAGVASRCSELRTEMRRLEIHQKQLVEDKNHKQQAYSKFMGLETKEEEAQAKVDEAKESMKGVRQRVDTLKEEIEQRTLERAQLTVDAARAIDALKGLHVQLYEAEIMQIEAGSDLEQLQARHADEQHQLEVKQQEVHQLKETTDQAKERGLEAQAKCREIQPTMTDKELEYYNEAESHWEDIDLDAEIQTVEASLESRLGGNENILQEFEERARKIEQKRAQEEGLVESLEQIRTSIENIRQQWEPELDRLVKQISDAFGENFERIQCAGEVGIYKDDDFEQWEIQIKVKFRENEQLSVLNSHRQSGGERAVSTIFYLMALQSLAKAPFRVVDEINQGMDPRNERLVHSRMVEIACAEHTSQYFLITPKLLNNLTYHPNMKVHCIASGEYMPDDHRELDFGMLAERALAVRAAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3I8</accession>
    <name>A0A9Q8P3I8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756172.1">
        <property type="nucleotide sequence ID" value="XM_047900764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3I8"/>
    <dbReference type="GeneID" id="71981494"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01616"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO11806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="354" mass="38667" checksum="456060D113576AD7" modified="2023-09-13" version="1">MSEGHPSTVTDAQTYRFISDPGHKENLSGRVRAACLTCRRKKIKCSGEPNCRTCREKGLVCEGLPERKRPRRDAPDVANHTLASRVGINRRQRIISGKRSSISQTAALSACEDFTDHNDHLTGRASTSLKDALSSTIDCKAQSGQIATRTLAQRNSSRRNSLPNQMHKDTWQVHQAPSQPQHNDRPAVPSMGGDTATSISTVSRLNQTAEPLPTVGDDRDDGTAGWWFGAGGEFVAMPPETRTRRQTVACLFPACDVADPRYQMPSGGYSFFDDSSLLANHTPAAEFTPGDFSAWLDANAPDLASMLPSTFPVDSVNAFNHPTRTSDALTIPLAQTAPNQDGHFEDYFNQGWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3J4</accession>
    <name>A0A9Q8P3J4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-mannosidase A</fullName>
            <ecNumber evidence="6">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Mannanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_02108</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756364.1">
        <property type="nucleotide sequence ID" value="XM_047901256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3J4"/>
    <dbReference type="GeneID" id="71981986"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02108"/>
    <dbReference type="OMA" id="PWKPAYI"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001511">
        <property type="entry name" value="Beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000084">
        <property type="entry name" value="Beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF5">
        <property type="entry name" value="BETA-MANNOSIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040459309" description="Beta-mannosidase A" evidence="16">
        <location>
            <begin position="22"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="20">
        <location>
            <begin position="32"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="17">
        <location>
            <begin position="258"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="19">
        <location>
            <begin position="745"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="18">
        <location>
            <begin position="848"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO11998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="932" mass="104664" checksum="2CC4217F6D9207E7" modified="2023-09-13" version="1">MRLVSRAALLASFLCNPLVCCQNIVSLVGSNWTLSNDNLSISVPAELPSYAQLDLFANQVIGDPLYGLNNFNLRWILWQNWTYTTSSPISGLSSNARSTWLLFNGLDTFTSISFCGQHVASTNNQFRQYWFDVSDILSSCSEANRTLSIEFGSAAKIANEIADEPGQEVWPDDVQQLYQFINRWFVRKEQSDFGWDWGPAFVPAGPWQPAWVVQLGASEVQVRNSLVDIYRQEQLNNLPPDQSKPWVVNASLDYFGELSAGAVLQYKLTTLDNKTTVANGELADISVTNSTVTGNTVIPSDAVELWWPVGMGEQCLYYLILELVSAANQSLATVTKRIGFRTIALNGNPVSEDEIALGIAPGNNWHFEINGQPFYSKGSNFIPPDAFWTRVTPERISKLFDTAIAGNQNMLRVWSSGAYSPDFMYDLADEKGLLLWSEFEFGCALYPVYPEFLANVREEAAYQVRRINHHPSLTLWAGGNELENLELPLANDSAPEEYPRLQAEYETLFLDTILPAVFGNSRSISYQPSSTSNGWLSLNHSAPRPMIQRYNNKTEGSVYGESDYYNYNPSFLGNTSSYPVARFSNEFGFHSMPSLQSWQQQISEKDLQFNSTTILLRNQHNPPGNLDTTNLTNSKVGQYQMTNAITTWLPVPNKTDSVANFTAWCHATQIFQAEFHTSQVEFYRRGSGLPNRNLGSLYWQLEDIWVAPSWAGVEYDGRWKMLHYAAKDRYEPVIIASYYNITTGNLTAWVTSDLWEPASGTATFTWYDWSGNKLDITANSTVQFDVGALNSTQVLETFTTDILQNHDVNNAILRMQVEAQGKLPNSNTTRTFKHENWFTPQGLGSAKLVDPGLKLSHSEESKNFTVTATKGLAAWVWLDYPAGAVLHFDSNGFWLAKDETRQISYTVESDMTGGRWVEGVTVQSIWNQTLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3U7</accession>
    <name>A0A9Q8P3U7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3U7"/>
    <dbReference type="OrthoDB" id="3600088at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395:SF22">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395">
        <property type="entry name" value="TRANSCRIPTASE, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="252" mass="29035" checksum="DF39B2A1DF068511" modified="2023-09-13" version="1">MSHALTQKVESCKTDIQLTVEEEREPEEKLNWKKANWSLVQEQLEGELEWVNIDNLYTTEGIDQAATQLVTAIERAAQAHIPKKRRARRRWEQQRTQANWETYNNACQAKKAQIRRDKQQEWRSTVGMITEHPEQIWRLAKWARKPEDEKNSLPQFPLIQDQRGQVQTTLKGKAEAFASHFFGTQVEADLSNIPGAHIPQPREASWHVDAKEIEGVIKKLKGNKAPGPDKIPNCYLKACRDLITPVLAPIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Z0</accession>
    <name>A0A9Q8P3Z0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_02205</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756680.1">
        <property type="nucleotide sequence ID" value="XM_047901353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Z0"/>
    <dbReference type="GeneID" id="71982083"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02205"/>
    <dbReference type="OMA" id="MQNAYRK"/>
    <dbReference type="OrthoDB" id="9992197at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </source>
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        <source>
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    </evidence>
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        <source>
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</entry>
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                <person name="Stergiopoulos I."/>
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</entry>
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    </evidence>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P676</accession>
    <name>A0A9Q8P676_PASFU</name>
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        </submittedName>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="OrthoDB" id="2417308at2759"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="GABA PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="203"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="237"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="364"/>
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</entry>
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            <dbReference type="EMBL" id="UJO15044.1"/>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P979</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="543" mass="61322" checksum="C6BC54695F6B56EB" modified="2023-09-13" version="1">MASSSQVSEASPLLRNDGSSSRPVPSPKPARNVTFNPQVSTSSPPKRRPNFPAQSSNSTTNLGSAALQTSGQDRPGPLATLNSKLRRRNSSGSALALPPSNPASKIGPQRTSRTAQKLKLLPNPDVAEDGPDEESGREVYSQFTRIKDPTARRDAARLGKDDRAKLPRVTAYCTAGSYRLDDLMRFLKGRTKTKNTNPKLFDECIYSPYTYRKEARNMDRRRRMSGDQEDQPDSPQATRIHSQPQRRFSDSALEVEENTEQRREDIIDFNNAETSAILDEGEPIDRQVSIDDANIISEAVIERRVEPDLDTTVHIPEIFLFEYGVVVLWGMSLKEEQRFLKEISKFEQEKLAKDDVQTEEFNFYYTREYQARIYNDFISLREKRNYMTKLAISHALAQSVKTSLYEDLVDATISTTQNIPSQIATTGRINLTRKQINMQIGELFILRINIHLQGSVLDAPELMWAEPQLDPVYQAVRSYLEMDQRVALLQERVSVIADLLAVLKDQLSHTHGEYLEWIVIVLIAAEIFVAGINIVVDLYAGVD</sequence>
</entry>
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    <accession>A0A9Q8P9J4</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
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            <begin position="207"/>
            <end position="226"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="25089" checksum="9995199EB0EC0820" modified="2023-09-13" version="1">MSQDQPQDSSALAPSSPWKVDFKWGKQRFLITDTSSIQDVAIIRCKLREPSLEFRTPDDKTTFGTGTVHAISIHPDYECNGFKGPLRASSRWATRYQPFFPNFGTPANPMVMSWTTSSSSKDWDFICLDDKGEAVARYATKIWATKKVGVIEFVGPKAEDLEARREILVTGVLMWYTMLVRVNNPLNLMYSIFGKAGPIRKDGGRGIVGDGGAEVGRDDEAAGSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9X2</accession>
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        <name evidence="3" type="ORF">CLAFUR5_07023</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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            <end position="727"/>
        </location>
    </feature>
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        </location>
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            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="786" mass="86258" checksum="F36F3BD9CB5F87CB" modified="2023-09-13" version="1">MEPVHQAAHTDALSMQKPSGNDSLHPHQASAWNYDDAHTAAKEARNSPVDSLLSANGKVPDHQIPQAPRLLEHAAASHDSLGHSESVERMDIARVVAPELPAEVVITLPVGLEDGSSVETQSFPTTESLHGCPPQVTRLIPSVVPQGEESDCSTVANPWFAPTRGVVCNSLHGTYARPTETFTSSVYSPSSTFLPATNGDAIRPRITANTQPPVTAGTFGSMHTPEVSGDARVEHDSQSAQHNPTDEAPAAVKFQEEATTTTSSLDGTSPETISTVEEAATPRDGSMPAQTRSKAPPLSQTPEPAANGTALAAGLYGRERNQKRAATKAYRQPITPRALRSADSKKPAECASSSSAASTETTKRAAPEFGSPKEKRQRLSSTAASTRARRATHPVDADERKSQVPQQAWESVPAQSDTSIRPIRDVEGDRRYVAQLQEVLEVRGKARKADMGRRQAARINDLLNLASYPTADEGLFLTREEATDIVASGKFFNGPIFTEGQQALPLQTVSQFCDEYYDDDTMVWIQDPEIKPTKKAQIARQVKMRQVKSRLAGPLSDKPWNCLELATHSDDGLKPSFLNTEDCRLLTKLKIPDTQDKPEARRRAYLPGYKEVEKWALLAQAGALTEPHQDSHGYSTYITINQGLVGYGWLSFPTDEERAAWRRNPDIFRGGRWRYVILKPGQTVYFPAGTVHFVFRLPDGGNTLAFGGHVLRCSNIVHWVKTLIEERNAKDVTNEDLTESAPGYLARVEKFVKQARITGQEAKWGGEESITEFLRLKEEFLKRKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA21</accession>
    <name>A0A9Q8PA21_PASFU</name>
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        <submittedName>
            <fullName evidence="9">Transcriptional repressor rco-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07411</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763012.1">
        <property type="nucleotide sequence ID" value="XM_047906559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA21"/>
    <dbReference type="GeneID" id="71987289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07411"/>
    <dbReference type="OMA" id="LTPDANW"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000111">
        <property type="entry name" value="Transcriptional repressor rco-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="8">
        <location>
            <begin position="18"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="379"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="427"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="523"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="565"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="603" mass="65569" checksum="6F903B022B0C44C1" modified="2023-09-13" version="1">MYNAHRGMPPGPQQPGSRLAELLDQVRAEFEAQAGRSTEHEHQLHAQIQEMELVRTKIYQLETTQIAMKSKYEEEIARLRHELEQRGGPSGSGHSAAQPPQPPAIGHGPANLFQGIMAGGQGGPGLAPPPQEQQGQPGMPGHMQGQGPPGLNQPPGQPHNPFAYGQPQAGPSLNGYGPQQPPQPTASPGGNKPRLGGPPGLRGPATPQQIPANAYPGSPQVARPTPPPNPNAQIASDFQYTPAQLENIGNQLSEYDPDKLPPHLKRTGDDWHAVFNPTVRRRLDVDLVHNLAHQSVVCCVRFSQDGRFVATGCNRSAQIFDVNSGKQVCHLQDNSTSSEGDLYIRSVCFSPDGRSLATGAEDKIIRVWDIQQKVIRHQFSGHDQDIYSLDFASDGRYIASGSGDRTIRLWDLHDSQCVLTLQIEDGVTTVAMSPNGRFVAAGSLDKSVRIWDTQTGVLVERTEGEQGHKDSVYSVAFSPTGEHLVSGSLDKTIRMWRLNPRQTYAIPGGPPPQPKQGECIRTFDGHKDFVLSVALTPDGHWVMSGSKDRGVQFWDPETGHAQLMLQGHKNSVISVAPSPMGHLFATGSGDMKARIWRYQPYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA32</accession>
    <name>A0A9Q8PA32_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763055.1">
        <property type="nucleotide sequence ID" value="XM_047906568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA32"/>
    <dbReference type="GeneID" id="71987298"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07420"/>
    <dbReference type="OMA" id="ICAKNRM"/>
    <dbReference type="OrthoDB" id="5339332at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="23747" checksum="AAAA42D4DFDBF4E2" modified="2023-09-13" version="1">MAQQPVLVRAYTDSRPSTALAPVPRTAARTQALPPISSFAFDDIFRSVDSPELQNAIQGIAEICAKNRMSLADEYASHLPPLGEITATNSRNMRSHVIRPSGGIRRALTSVPEGSSGSSEGSRKSKKKASLFSFGKQQPQESKPMRRIRIGSMGRMVPVGTTTAMAAHLDLSQQDHTRKSSQTTITPETAARPASRPRSLSAAQTSLQRLLGIERNVQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA56</accession>
    <name>A0A9Q8PA56_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763057.1">
        <property type="nucleotide sequence ID" value="XM_047906570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA56"/>
    <dbReference type="GeneID" id="71987300"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07422"/>
    <dbReference type="OMA" id="IFRYGPT"/>
    <dbReference type="OrthoDB" id="2446447at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02219">
        <property type="entry name" value="cupin_YjlB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047121">
        <property type="entry name" value="YjiB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448">
        <property type="entry name" value="BLR7373 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF3">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="1">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="227" mass="25173" checksum="4A495C77A0608146" modified="2023-09-13" version="1">MPEVQVNPYHLKPTSLIPNSPYPLLHYKGLMSSHIPSNSGKLSSIHNLYTSNSWVTHWIFRYGPTQLSHYHSHAHECMTVLSGTATIRFGVADTSEDMDENTYKGQWEEGGIEVTAHAGDVFIIPVGVAHKTYNPSPTSPEVKLLTPGTGKGVEAADPAKALDAIELEGFTMMGCYPEGQTWDFAVGMEPREFKEVWSVPKPRRDPVLGDGEEGLVGLWRERERAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAP9</accession>
    <name>A0A9Q8PAP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Purine-cytosine permease FCY2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_07074</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763385.1">
        <property type="nucleotide sequence ID" value="XM_047906222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAP9"/>
    <dbReference type="GeneID" id="71986952"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07074"/>
    <dbReference type="OMA" id="RYIQMIS"/>
    <dbReference type="OrthoDB" id="5428495at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G03000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="15919" checksum="0D07C21D000F1FEA" modified="2023-09-13" version="1">MATDDAEIGNGKPYAHIDDTGSSNNPATSIREGYVGQQSLPKRLWYSIRSELTETRGVARVPPEEKQAPYLSRYIQMISLWTSANLTANHVALGLLGPSVYGLFFLDSALCAVFGVMVGSACTGYIATFGPQSGCRSMIIARYSMGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAR5</accession>
    <name>A0A9Q8PAR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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            <begin position="240"/>
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        <source>
            <dbReference type="EMBL" id="UJO19018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30118" checksum="34C1DC0D1A8E1FB6" modified="2023-09-13" version="1">MSEPCEFTMAATEPVPTTMSTEELARGLLERLAAGGKLSHTTSTSLTTALASAISYRPESNTTAAHDVFHIPELLESILINNNLTTITTCQRVSRQFQATIASSAKLQCGGKKKSKTFKPELNPLLSDPTFCTRHAINAFTYELREDKDFRLLIDITFGTLAQLRALKPGGWQKLLLVQPASKRLDRWNLSFTYGEGKFTRSVGRGTWWDAVTLGEMVEVLLERWEELEGDPWMSVSEWDPERRDVGKGREHGGRKVVAKSEEQGGAEGVD</sequence>
</entry>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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            <end position="166"/>
        </location>
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            <end position="379"/>
        </location>
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            <dbReference type="ARBA" id="ARBA00023127"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="44006" checksum="15B35054EF1D32AB" modified="2023-09-13" version="1">MSTAGRLSEDDIYRTSTQYRLWSFSPEQLAAQRRKTHELALTRAHQHASQTADRPQNGTSQPEYLTEREELRLVHRYCELIQTTADHLKWPSNIKPVAVQYLKRFYLSNSCMTYPPKEIYKTMLFLASKTEAYHLTVTKFAQSISADPEAILAPEYKIMQALRFTLDVRQPFRGLKGVLMELLNMAEGLVATVKGVEQRSERDVQEALKQLKPPPQDCRTPWKAPPDGTMGKKHFIDRIQASYATAKTLCDGPASLTDAYFLYTPSQILLAALHIADSPLAEFYLDTKLPLTLDSRPKILATIQACAALLASYNPKDSMGKEERAALEKKLDLCRDPTTKDLIKAHAAMKRNGAEDGKVDEHDAKRRKLEREKREKEDPFGPSLGNGKV</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="195" mass="21397" checksum="5C88F4331AE5A681" modified="2023-09-13" version="1">MATTPPAILGLPAELRTMIWELVLLQDRPVLLAPRPLLIEQGNYFKLCNSIEPGLLSTCKHIRSEGLLLFYASNRFKFVDNGPLLDAPKGYLSLLKWLQGTGDTGISVLGGLVLQSTAVWPAYAIGRLQWPVSADRPACTDMEAAEILARRAAERMVIVLSLAGGQMYPTFNIPEVTGTRNPIFKTSEVTGNRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAV4</accession>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
    </reference>
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            <begin position="30"/>
            <end position="620"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="620" mass="61811" checksum="93AB07E6E03399F2" modified="2023-09-13" version="1">MYRMSSKSGHSLAMHSLALLPLYLGIANAQLGINLDIALGLPTGCPSAVTITVLPDDYSGTLVGQPTIPCLPTLLPGGNPLTNLPVVVSSLIDTLPTGSPLSNLPDIISSVLGNLPTGVPVTNLPDVISSVIAGLPTDTPLTNLPDVVSSILGGLPTNLPLTNFPGVLSSILDDLPLPTPTRPNTAGAPITAIPAQITSALGCIPTVAASAVPALLSSVLESLPTDLPLEAVPAALSSVLGCLPTGLPVTQLIDEVSSILETQPTLLPVSSIFSGLQSDLPILTELPDALSSILAEVPGVVTGLPGVVSSILSGLPPAVTGLPGAVESILSNLPGVVTPLPGAVESIVSEILGGGRNGLPLLTPTINIPLTTELPNALSSIIAGLPSDVPLTNLPGVVSSVLGNLPSNLPIISGLESGISSALNGLTNGLPVSVINSALSSLLGEIIPTALPTNNGNPLTNLISGLTNLLPPVPTPTGNNLISTTDANGRPTLISITPTVILPDVTVSNPSGLSLPTNLIPTTGLGPIISNLIPGLSSLLVGPGGGSGRSATTPAAIPTASVRPVFSCPSASGLAYVAPNGRAYQITCSTNYAGYDLSTSLQPDMYSCVNSCSGVAGCME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB53</accession>
    <name>A0A9Q8PB53_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
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    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07454</name>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763553.1">
        <property type="nucleotide sequence ID" value="XM_047906602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB53"/>
    <dbReference type="GeneID" id="71987332"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07454"/>
    <dbReference type="OrthoDB" id="3360610at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="163"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="35251" checksum="BA0084CD676694FF" modified="2023-09-13" version="1">MADSPGPIKLLKTAFVDYHHANLPKVKDFLRDFGLDVAHENPDGTTFFKGYGTEPFIYIARPSPNGSSSFGGAAYVVEGESELERAAQLKDAEGPIRNLEGPAGGRAVTLRDPAGHAVHLIHGWQETTASPPHLQKLIINFEDDKPRKGKFQRFEPGPAPVFRWGHYGVTYPEGLYEQMYSWYTTVISLAPSDIVYRGEKSVTCFFHYTDHHAFFFKMVKPGDRPSVAHAAFEVHDFDVQQLGHQHLTRKGYELCWGVGRHVLGSQVSDYWFDPNEFILEHYADGDLVNRDTPIAKVQAGPEALSVWGPPVPEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBL1</accession>
    <name>A0A9Q8PBL1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763807.1">
        <property type="nucleotide sequence ID" value="XM_047906490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBL1"/>
    <dbReference type="GeneID" id="71987220"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07342"/>
    <dbReference type="OrthoDB" id="1044435at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="4">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="23695" checksum="1C4227FA7E1497A2" modified="2023-09-13" version="1">MAATALREPPADTPRSAFFYGTLMAPKVLHRVCHGSMADDNPIYKPHNFKTYPSILHDHQRKKVKRADYPGIVPKPGSSVRGTYVTGLTSNDIWRLDMFEGDEYSREKVKVKVLKEVGNERGEGNIEGEEVEAETYIWIAGEERLEDSEWDFAEFQKEKMRYWVGAEGVGEYAGRASIIGVDEAVAAAEKDGTGGRGANGAITNALNEATRNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCM2</accession>
    <name>A0A9Q8PCM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764427.1">
        <property type="nucleotide sequence ID" value="XM_047909497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCM2"/>
    <dbReference type="GeneID" id="71990227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10349"/>
    <dbReference type="OMA" id="GWLIWRV"/>
    <dbReference type="OrthoDB" id="5421757at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="39804" checksum="F22DEF9B0A91EA90" modified="2023-09-13" version="1">MAPKGFKQRAKQDKSTSTQIPAPFTKAPSSLEPLLQRFDPKLVHITHIDRQPADYKKSIFLIPVLLNTTITALLLWRLYVAVPKYFTLAQTLLGYYTPLTVDTTSTTRKQQIGILLRRTLMFLLDFLLFRFVGPWPLTFFLERPSNPVHYRWKLGFRKDEIIVRVSRGWGTEDLMQGVKQGEENPFFKTRVLPAISREVMGKTGYLMMDKSWDLDFEVMLDSHELVKREDVKSKELDKVVFAFLEGAGWVQWKWEGEGQVDVVEGRRQKVVAFKETLGKMGKESLFWKWTEIVEEERDKDGGFTRERQERVAKRVQMEFEKNGVDFDEVVKSSGGLDEVAPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCR5</accession>
    <name>A0A9Q8PCR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10364</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764393.1">
        <property type="nucleotide sequence ID" value="XM_047909512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCR5"/>
    <dbReference type="GeneID" id="71990242"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10364"/>
    <dbReference type="OMA" id="PCRKGAH"/>
    <dbReference type="OrthoDB" id="10264777at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000065">
        <property type="entry name" value="N-acetylglucosamine-6-phosphate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="11">
        <location>
            <begin position="66"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="343"/>
            <end position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="434" mass="47851" checksum="4EA72AA36D37EBDD" modified="2023-09-13" version="1">MPIAVSPERPRTGVTRITGGRMVKGDQLVEGDLWISSVTGKILHSQEVFYEHHVVPDEIVDLKGKILAPGFIDVQFNGAFGFDFSTIPEDMDTYAKGVKTLNRHLVRTGVTSYLPTLPSQLPQVYHKALPHLGPSGHSRSAMEGSESLGAHCEGPFLSPTKQGIHSLEVLREAKHGFQDFEDCYGNENLLEYRRSPITMITAAPEVSGVSGLIPEVARRGIVFALGHTEATYEQAGEAVEQGATMITHLFNAMRPLHHRNPGIFGVLGKAEEKKRPYFGIIADGVHLHSTTVKIAWNAYPDGFILVTDAMKTVGQPDGIYDWTNGDRFEKKGTLLTREGSDVIAGSCATLIECVSNFWTWTHASIPDVIKTVTYTPAKMLGLEKRKGVLEADADADLLVLDVREEADGRRVFEVDQVWKFGLKVHDRQNERIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCT1</accession>
    <name>A0A9Q8PCT1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_10348</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764426.1">
        <property type="nucleotide sequence ID" value="XM_047909496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCT1"/>
    <dbReference type="GeneID" id="71990226"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10348"/>
    <dbReference type="OMA" id="KCFRREV"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO20060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="27085" checksum="315A768BBD5C9AF0" modified="2023-09-13" version="1">MSTQKNKYSVLLPTYNERRNLPIVVWLLNQTFTEHKLDWEVIIVDDGSPDGTQEIAKQLIKAYGPSHIKLQPRAGKLGLGTAYVHGLQFATGNFVIIMDADFSHHPKFLPQMIKKQAEGNYDIVTGTRYAGDGGVYGWDLKRKMVSRGANLFADTVLRPGVSDLTGSFRLYKKAVLQEVMNRTESKGYTFQMEMMVRAKGMGFKVAEVPISFVDRVYGESKLGGEEIVEYLKGVLSLWVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCX9</accession>
    <name>A0A9Q8PCX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764615.1">
        <property type="nucleotide sequence ID" value="XM_047909047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCX9"/>
    <dbReference type="GeneID" id="71989777"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09899"/>
    <dbReference type="OrthoDB" id="10605830at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="278" mass="30359" checksum="E57231C715CC700E" modified="2023-09-13" version="1">MTRTKNNPAPQATRTTAKTQVDAQDIAAGDYQGKKNEDLVGELGRRGVPRPAKINKANLIEALEQDDKKNSSAPQQTKSGARVSKSSAAKSTARPAHFRTIPRIDPVRLRLLQGQVMDIAGWLSAEEDDRLDSIINILGRADRELDRLALTYPPLKAFPKRRTSSAGDPGRRLPLTGGARYGSVDLDAPSPPRRSSLRIQAGRFGSVGADPLSNSPVIPPRSIEEVDDEGEAPTGEGEEEEVDGPEEDDQEEQEIISIPSNDKFDDEDLDELYELIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD74</accession>
    <name>A0A9Q8PD74_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Actin-like protein arp5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD74"/>
    <dbReference type="GeneID" id="71989890"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10012"/>
    <dbReference type="OrthoDB" id="7340501at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10211">
        <property type="entry name" value="ASKHA_NBD_Arp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000054">
        <property type="entry name" value="Actin-like ATPase domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000122">
        <property type="entry name" value="ARP5 actin-related protein 5 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="386"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="753" mass="86248" checksum="5FDC91815637141B" modified="2023-09-13" version="1">MPHFTVPIIPPDSGRNSPKEPPETLFSVSEPPYQGQLPTNTSAYRATLPDTAIVIDNGSSTIRAGWQTDALPRLQFPPLMARYTDRKLNRKLMFIGSELYFDGTSRGQAKNVYEPQSSNVVNNWDVMEGCLDYVFMKLGIKDQERIDRPVVMTEPLANVGYARKTMSEILFELYGVPAAAYGVDSLFSYDYNGGKTGLVVSSANMSTHLIPVVDKQPLISHATRLDWGRSQCSEYLARLLRAKYPGLLTTGKVNETQIEDLVKSHCYVSQDYDGDTLKMLEWTGLEDRDHVVQLPFQEKEVVQKTEEELRIAEEKRREGGRRLQEQAAKMRLEKLIRKEQELEYFKQLQQQIAEATTKKEIRALLDEEEFKDEQQLDRRIKEMEKSIRKQRNKDVGDLEEEAEEPPSYPLLGVPDEELDEDGIKQKRQQRLLKSNHDARARAKAEKEAGKERQAEIQRQDDARREADLEEWVGERRAARQEVIQKMKERERLKADLSNRKSQASQMRMKHIANLASDNPNGRKRRRGGNDDDGFGADDADWMIYREIQAGKNDDEEDDEEEDLGGQLKNIEKQLLQYDPDFTEQSTQEAQKDWTKSLLHAFSRGPFPFDPESAKESAQFHLNVERIRVPEVVFQPSIAGVDQAGIVEIAEDILMQRLSSHASRDAILKDVFITGGYSLFQGFEERLRTELRAVLPAELQLGIRKAKDPVLDAWKGAARWAGKTENRQSFVTREEFLEKGGEYIKEHGCGNFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDC7</accession>
    <name>A0A9Q8PDC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pre-mRNA-splicing factor slt11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09833</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLT11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764708.1">
        <property type="nucleotide sequence ID" value="XM_047908981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDC7"/>
    <dbReference type="GeneID" id="71989711"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09833"/>
    <dbReference type="OMA" id="CPLRVQW"/>
    <dbReference type="OrthoDB" id="10259600at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000396">
        <property type="entry name" value="Putative Pre-mRNA-splicing factor slt11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="248"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="157"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="335"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="391" mass="42427" checksum="4A636FACA7397203" modified="2023-09-13" version="1">MPPQIKQDLNRSGWETTDLPSCCERCLGDNPFTQMLKEDYGEACKLCTRPFTVFKWKADRTSRQKRTGICLTCARLKNCCQCCMLDLAFGLPITIRDAALKMVAPGPQSEVNREYFAQNNEREIEEGRGLEGYEKTDEKARDLLRRLASSEPYYKKQRRLEAEAESEGGQKLLEGGSSAEGGHKPGPIRTADSRPKSQYGSAYGPPSRGGAAPRGGRGGARGGRGFPGGAALPIKPEDIAPPRDTNITSLFVTGVEDDMPEHEIRSHFQQYGALRSLVCSHRSHCAFVNYMEREGAEAAAAACQGRAVVKGVPLRVQWGKPKPLDNMDRDQRMENARAGRAVESRQKAIAGPAGQKAIAGGSAQVEDLDSLAAVAPPPGQGEVEYAAMAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDQ9</accession>
    <name>A0A9Q8PDQ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764917.1">
        <property type="nucleotide sequence ID" value="XM_047910234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDQ9"/>
    <dbReference type="GeneID" id="71990964"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11086"/>
    <dbReference type="OMA" id="YCFNGFG"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF81">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="75"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="519" mass="57605" checksum="C52D059AFA0397D7" modified="2023-09-13" version="1">MGPQKRPSNEYELEKKSSALTKIVSAPDLKAGEIKDLDQAEIFLQDNGISHDDLQAMLQDKEGIKKLVRRVDWMLMPLLCGTYLLQYIDKQSLSYAAVFDLFTSTNTNQTQYSWLISIFYFGYLVAEWPASYIAQRFPTGKVVSISIIAWGSILMLMTASHNFVGLAICRFLLGCLKSMITPVFMMIVGLWYQRKEQSVRAGAFYCFNGVGATTGGILFLAVGQAKGFPIWRAIFLLAGGCTVCWGFLLLFFLPDNIMTAKRFSPQEKAMLIARSQQNQAGVFNPKIKMSQVKEALTDAQVWLLFLSVLLNETVNGGLANFSKLIIKGLADGDALLTTAYGIPTGLWQVFFVFSGPWLAGKLKNCRTYIMPLYLMPTLLAVILLWKLPHSEQNNKGLLICNYIAGSFVASLVIALQLPANNVGGYTKRVAATAFVFLAYCAGNITGPHAFLKKESPTYSTGCIVSLACVAGQVVVSFCLRALLMRRNKTRDELYGPPQAVTGEIEDRTDFENPNFRYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE21</accession>
    <name>A0A9Q8PE21_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765111.1">
        <property type="nucleotide sequence ID" value="XM_047910581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE21"/>
    <dbReference type="GeneID" id="71991311"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11433"/>
    <dbReference type="OrthoDB" id="10410443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="26412" checksum="592D73244423E416" modified="2023-09-13" version="1">MSLIKQSKITNDQAPRNFYRVTDDSSYVQIDECGNFATGCTPFYHLSYIINGKNLNLHLDWRYRFDNEDPNDCPMFISMTDSRKWAQEETERRLARGCTNRVTDSTSLTRIDPSGNFDTNCQLWGHWSFWTSIMNGPNHSSQIDWYHRFTPTTLDGQGDDPPLFVSLTADCGWAYDEFDRRARRRRDQVRINVIDTSDFECEVVFLENGERLPVLRERETGCTIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PED3</accession>
    <name>A0A9Q8PED3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclopentanone 1,2-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765238.1">
        <property type="nucleotide sequence ID" value="XM_047910152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PED3"/>
    <dbReference type="GeneID" id="71990882"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11004"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="56998" checksum="359E77E2ADC96DA1" modified="2023-09-13" version="1">MGPIAEPEIPYTDVLLVGAGFATYTLLNKLRRQGLSVKILERGASAGGIWYWNCCPGARVDSDTPIYQLFDKELWEDFTYKERYTLHGPSFDDTLSTSTRTTFDTKKSQWLIECTDESQYWCKWFIPNLGFALKNYSPPFPDINNFKGEKRVAVVGTGASGIQTIQELGPKTEELTVYQRTPNMCLPMNQKKPDPAEEEKKKQDGTYEKLINDTRSTFAGFTYDFIDKKTFDDSPEGGFRYWLNTYSDMLFDDKANDQAYDSWRRQVLKRMTDPEKQKILAPERKPHPWGTKRPSLEQRYYEVVNEPHVEITDVNANPIEEVKAEGIVTPKGLREFDILVLATGFDSVTGSLAQLNIQDTEGRTIGEHWKNGTKTSMGIAIPGFPNMFFCYGPQAPTAISNGPSCTQFQAEWIEEAMKRIQKDGITKFEAKQDAEDDWCKRMNEAWDATLFPMAKSWYSGGNIPGKNIEPLNWAGGMPEYVDSLHKSLENDYQGWHYAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK7</accession>
    <name>A0A9Q8PEK7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765343.1">
        <property type="nucleotide sequence ID" value="XM_047910649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK7"/>
    <dbReference type="GeneID" id="71991379"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11501"/>
    <dbReference type="OrthoDB" id="3629888at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="12950" checksum="A79566CF4D3E33A5" modified="2023-09-13" version="1">MATASSKLTPLTLPRELRDLIYEFTFSEVIGLSFSRPDHNTPIRNNGGLVLTNRQIHNEAITKYYRHSIFYTIPEYTSLCGTQLCRQNTATRSEVSGSGRLSGRMRVPISGQGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEN5</accession>
    <name>A0A9Q8PEN5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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</entry>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="28050" checksum="F936079DCA70F748" modified="2023-09-13" version="1">MLFAAQSHASQAKELPLTEPSFNDSVDTTAHHSITHHSTARMTTNMATTTPFASADKRVFNIGELVEPILTHVRSGDEQNKAQVVDDMKTILRSQQINSTCRKAVQSSHHIKRLLGMLPPKVSDTTSFGIHPVFQVPAPGGATDGPLWGWRFARHAFTNSSINATSAKTLVLHVDAAAIEFYVHDKGSWRQLCWNLRGYEVDSCEIHLPGKRKGMQRFSQILELRIGGRETAGELVDAVVKRVQTECPAWRTT</sequence>
</entry>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </feature>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="30797" checksum="4CC960D52F58B538" modified="2023-09-13" version="1">MSILQLLITSLLPPLAFSSPHAKRVIPQNDFTCRSTTHPNPVVFFHGLGAIFHEDLNFLQLYLQSQGFCTFSTTYGEYDAFPFVGGLKPINASAAELATFIHEVQSKTGAGKIDLVGHSEGAFLTLYVPKFTDTAHLIDKIIAIAPPTHGTDFGSIYDLAYLFSNVSREVVGDVLQTVGCAACDELGPDGAAVKALTNGTSVQPGNQVTILTSRYDQLVTPTTTSWVDEPGVRNLYVQKFCPLDFVGHIGEAYDLNVWAIVRKTLTGLAEGKVGPDLCVTVPFWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
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        <alternativeName>
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        </alternativeName>
    </protein>
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        <name evidence="13" type="ORF">CLAFUR5_09148</name>
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    <organism evidence="13 14">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766690.1">
        <property type="nucleotide sequence ID" value="XM_047908296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH49"/>
    <dbReference type="GeneID" id="71989026"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09148"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04323">
        <property type="entry name" value="AsnRS_cyto_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048952">
        <property type="entry name" value="AsnRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF16">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20917">
        <property type="entry name" value="AsnRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="274"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO22324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="575" mass="65808" checksum="DE12931059ADDEBF" modified="2023-09-13" version="1">MADADRKTIYIDEEVGQDTAEVDGSQAKPYQSLSYAYLQHGAVEYQVKKKEGDEEPQYKPAAKAALKKAVNYADQQKKKAAKEQEIAIREKKEQEDRQRVFEEAKKIKIEEDKSLPKAVKIHLGEKRPEVVKLGSGERSKGADYSSPNRGTRVRVMGRVHRERKQKEVLFVTLRDGHGYMQCVVTGQLAKTYDALTLTRETSMMITGEMWEVPPGARAPDNRELQADYFEIIGKAPGGEDAITNVVQAKGDAQTLLDRRHLVLRGETSAAVMFVRDAVEHAFNVKYHELGYVKVSPPALVQTQVEGGSTLFEFNYYNEKAYLTQSSQLYLETAIPFAGNVYCIEKSFRAEKSLTRRHLSEYTHVEAELDFITFDDLLDHLEEMICGVLELVLSNPRIAAYLQDLNPDFQMPERPFKRMRYSDAVQWLIEHEIPNEEGEPHKFGDDIAEAAERRMTDIINRPIFLTHFPAEIKAFYMQKDPEDKRVTESVDCLMPGVGEIVGGSMRMWDYDELMAAYKHEGISPDAYYWYTDQRRYGTSPHGGYGLGLERFLAWLCKQHTVRDTCLYPRYMGRCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHJ9</accession>
    <name>A0A9Q8PHJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766930.1">
        <property type="nucleotide sequence ID" value="XM_047911349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHJ9"/>
    <dbReference type="GeneID" id="71992079"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12201"/>
    <dbReference type="OMA" id="ANIRDAC"/>
    <dbReference type="OrthoDB" id="3641574at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29450" checksum="5F5040A4CA83C699" modified="2023-09-13" version="1">MVVTSHQPDIRFCKIFADDRYTLDWLIDQGVDVNKTNTSRQATGYAGPQDIFDWSDHLLNNVAANGDFELFDHLGSRGADPHRSLALHDISRCRDEARAVAMVRQLLDKHNMNIDSDNEDMRDMFDLAPDSGTPLCVAACYRDFPVLEELLRRGANPKQRGKSGIYPLNNAIGTKNQEASLPAIEALLGAGVDPTSVLVDAAEHGKLGAARMCLRLGADLQEAREEALRRDCELAGYGLTLAQRAQGRESIEDVLSKLMAKSGSAPEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PID9</accession>
    <name>A0A9Q8PID9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767421.1">
        <property type="nucleotide sequence ID" value="XM_047911457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PID9"/>
    <dbReference type="GeneID" id="71992187"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12309"/>
    <dbReference type="OrthoDB" id="3649723at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25378" checksum="8A308F6DA6B4FC96" modified="2023-09-13" version="1">MDEPKREAARVRQVSAAAGSLPLESPSVTDLPPRDSSRESPPKSAAERVFAIVELAEFILLESPPRAVLRNRRVSKVWQATVLGSKALQQALFFEPVIAGFKETSIHHPYLRQITSSDVYSNESDPSASWRRQLLNQPPVLDCKLRVECEQTQTCRYHLNDSPGVRLGAVNDTIRRRSISHRRCGCLSIRKWHTSEAYLGEWSWWTFGEKPAREWLAAMKRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF0</accession>
    <name>A0A9Q8PIF0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="11">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_12002</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="11"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767377.1">
        <property type="nucleotide sequence ID" value="XM_047911150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991880"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12002"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000027">
        <property type="entry name" value="Probable exopolygalacturonase X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF14">
        <property type="entry name" value="EXOPOLYGALACTURONASE X-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="29"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="240"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="361"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="561"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="703"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="839"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1093"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1159"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="485"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="843"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="855"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="887"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1093"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1159"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="active site" evidence="15">
        <location>
            <position position="1549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO23011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1730" mass="186299" checksum="5D1FF89BCD3E7A7A" modified="2023-09-13" version="1">MCKYRYYYYAGCRHQETVLHDYCDKATSAPASSSAHTISPATTLPPSHAQAGGAHEDQDATPRARSPANVPSPSPTMSTSSSSHHTTASNVSIGSSAPTSFASSTGDTPDTSSIQFEEPHRRHSEPSECNMASLPPFVRDNLRQFFSGGQITTPPTGTFGDRHVNDQDQENLQPIETANQNRHSDSAHAANTTKLVVDRLSDVVAGKNRNASYSSVESTMSESEFDAIERDIDTLKQQVAGLRSGSRSGRSAPTGVEHQTQSKSSSTRTRIPGPVAPPKESAAARLQREHEKAHEQHTRSSGSHQAKPPPPPPSPCDFPELAQSNTDQRPRAFTADANRDKPSYANMATTGMMDALSRRFAGTEGTHSQKMCSSGSASRSTRGSFTSSSRTDAMATEGQMHTASAVSPECERSSASKDQTSSLAGRSPRFAQPTKTYTQRADATTRKDSVTSRVSPAGSPTKSSRALPQLQTKRSALPGGWLSSPEVSPTTHVSTPSINGTVDASSPSSNERWQFISQSSKETATNAEPTLRKKTSSYMSPTKATTLRNVATLGQENIKHTSPRVKKSVTRIDTKVSPSHKAMNSANSHQPDSAISGTTSTESYMSSPDVAILTEGRAINPWNLHQTHVGEKTLVGPTPTSFEPAIRAAGAHDRNVLPRINTVLPCGVEEVQSSTSDPASALFGHVELQNTSIATGECVKTERSLGSSRGHEHPELAASRKQTATNKSIPSSAVPIVRPHTSMPEPMPRKLHAARQSTTGSLGLVVDDLAAKAKARGLPMPANTVAKRRVSHGHLLIPITSKLDSLGLLRQPAAASSPATSQATPFSTAQQQVRQLLPQTPHMSPPLEPRPVPAAPRVRTKAVPPHLRRKHNTSSADEPTELYRDATGSNDNRISGSACQDFARSSQVPSLRATAQEFTPKWKPKTIEQELGLLDWEGWFSYRSPEEWNALHPGIRAAIQAIREYKCKGGRPPSGTFPGMSPTKIRSKTANQRFWANLMQNQTPTSNSDSSINMSPGDVVAAMQESIAQYGASGNVEAGQVLKPEINPETNAIQWVMQEPDGRKVSVTFGRAAAPAPALGSCGAFDSPSTVTISPNSLDSSQRYNAPSPEQSSNVFRTPSGNHNRRGWSIASALRDPTGWAIGDGREIRYVGNGNANTASHYSPVAPSQQGVREGPDQAPRMIGDEQDSGSGSIPLAPRSREQWAKLLPQTRMPCGNIEVTDAIEQIPMSAMDGAPLYGFCGPCSGLALPDFVHHLRPPPPLTRTMFSQLSIPAVLLHAFGATASWTAYQEYQASLPKNCTKSPSKRPELSYEPNAPFLDLPASPSRNRTCFVKSHDDLTTDDSEYILSALHECNHGGQVVFPQGTTCVVGTALDLQFLKHVDIDIQSYIQFTNDTDYWQENAFYQTFQNATTFFQLGGEDVNVYGGGMLDGNGQVWYDAYAEDIYILRPILFGTIGLKSGIIADINLRYSPQWYNLVANSTDVVFDGLTISGYSQSEHEAKNTDGWDTYRSENVVIQNSVINNGDDCVSFKPNSTEILVQNLHCNGSHGISVGSLGQYVGEVDIVENVLVSIGRFEKIYNISMSNASDGARIKVWPGSPVALSGDLQGGGGSGRVKNITYQDMAITNVDYAIEITQCYGQKNLTLCNEFPSNLTISDITISNIHGTTSTKYDPISGYVVCSSPDVCSNITLNDIDVVSPDGSENLFTCGVVDESLLHDIDCTSTKDGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIY7</accession>
    <name>A0A9Q8PIY7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux pump FUB11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767885.1">
        <property type="nucleotide sequence ID" value="XM_047912133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIY7"/>
    <dbReference type="GeneID" id="71992863"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12985"/>
    <dbReference type="OrthoDB" id="5410178at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF157">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="202" mass="21996" checksum="6488ED0A0FC82C45" modified="2023-09-13" version="1">MPGIFDAYDPPLGPFEKIIPWIAILAGLLFSIFTRSWDYWRLRQHKAADITPEDKLASFAFAAPSLAIGLWWFAWTVPDHEDTQAAVSWVVPAMSLVFIGWALNEFDMVLAGYLTDTYNAYSSSAFGAMNLVRCVLSSVFPLVAPKPYGSLGTHLAGTVLAAAATAFCLVPPIFLRYGAAIRGKSKVAVVSAVLNNEDQTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ80</accession>
    <name>A0A9Q8PJ80_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767755.1">
        <property type="nucleotide sequence ID" value="XM_047912238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ80"/>
    <dbReference type="GeneID" id="71992968"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13090"/>
    <dbReference type="OMA" id="AHIISIY"/>
    <dbReference type="OrthoDB" id="2997776at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="32667" checksum="A73735281DE4CA05" modified="2023-09-13" version="1">MRIHKVLMLELFFDRLEGPNDSRCVFKEDPKSTGGPSKGASETFRRTYEKKKGQQWRRALDEYMGIKHGRRTKIRQFERPAHIISIYGHSLDSVLPGLEYDIENRELSFQWEPMLAAFFSEQHELNRRSEGLESYSELADQFAAEQIQPYSGHLRFALMAVKLQKAAAAKEKVMLRVRRQRIMKQYREFYTEERIDKDYDVDAHDEAVHVGKVVAVDGAGTGRERTGSGMTNDASDEDSADDQDEQENDSEAEEDDDPDYASVSSGGDPIEGERADEYHDLSDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJL4</accession>
    <name>A0A9Q8PJL4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767981.1">
        <property type="nucleotide sequence ID" value="XM_047911665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJL4"/>
    <dbReference type="GeneID" id="71992395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12517"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="60" mass="6577" checksum="E39C3D4413C24443" modified="2023-09-13" version="1">MAAALVDGSYNGILNDEIDDAEQSHAQKFIKKRYIDRSSLESASNYSLVEKAPDISSSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJW5</accession>
    <name>A0A9Q8PJW5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12876</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768133.1">
        <property type="nucleotide sequence ID" value="XM_047912024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJW5"/>
    <dbReference type="GeneID" id="71992754"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12876"/>
    <dbReference type="OMA" id="STDQEHG"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040458826" description="beta-glucosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="639" mass="69491" checksum="7C238785C89055A0" modified="2023-09-13" version="1">MGANAMMLQLLLALTASTASCSNLPKKSLASRSPHPRSTSNTTLPYQDPSLCIDDRIEDLLARMTVEEKAGQLFHTQLAQGPNGTLSLTTSRSNGTDNYVLEKHMTHFNLVGQVTNVRQTAQWYNRLQEYALNTRLGIPVTLSSDPRHSSTEAVGSAIAANQFSAWPQSLGLAALRSAEIVQKFAEIAAAEYKAIGIRSALHPQIDLTTEYRWARIGGTMGEDADLTSELVVAYLKGFQGESFGTHSVTTVTKHFPGGGPMENGEDSHFTYGKNQTYPGNNFDHHLIPFRAAIAAGARQMMPYYSRPIGAEHNGMEIEPAGFSFNKYIITDLLRGELGFNGIVCSDWGLITDTVIAGQDMPARAWGVEYLSETERAARVLNAGVDQFGGEARPELIVQLVNEGTISEARLNTSIRRLLREKFALGLFENPFVDVDEAAQIVGNPYFRQLGAEAQRASFTLLTNNGTILPLKVNSDNSTKVYVEGFNSTFLSSRPVTVVDTPEEADIALIRLQAPYEPRPGGFEANYHAGSLEFNATERARQAAIFEAVPTIVDIYLDRPAAIPEVAEGAAALLASYGSSSETFLDIVLGVDGAAPKGKLPFDLPRSDEAVEASDEDVPFDTTDPVFKFGHGLEYEKHAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK39</accession>
    <name>A0A9Q8PK39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768357.1">
        <property type="nucleotide sequence ID" value="XM_047912361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK39"/>
    <dbReference type="GeneID" id="71993091"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13213"/>
    <dbReference type="OMA" id="MIAQADN"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18850" checksum="31AD775C07AAECEA" modified="2023-09-13" version="1">MAPQQVKPFRLLDLPPELWSKIGQLIVDDASTVTEKKLYWIHHPYPSSAQELAEIQQPATTRTCSILRAELLPYYYQSKISISVIASSLASRVVGKWLRMIGSKNRSVVTGVWLTLYGTRDKQSQLLREDFQVDFQLSWTARRERERGLYGREQDYVSLEFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK66</accession>
    <name>A0A9Q8PK66_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13146</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768366.1">
        <property type="nucleotide sequence ID" value="XM_047912294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK66"/>
    <dbReference type="GeneID" id="71993024"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13146"/>
    <dbReference type="OMA" id="MTSIGCF"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040231298" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="31"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="50"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="32136" checksum="0A4C60D0A220EF4B" modified="2023-09-13" version="1">MPSTLRATTAYAAHTFTLLSLLTASAMAHAAPSLDDLGSMHMNDMQKRVPNGYLGCFSSSGSLDDLGSYMYQASGYCLEKCSGQAITALTGGDTCLCGDIAPSLGDKVDNSKCSINCNGYPVEKCGGDGFYTVYATDGQVGGVEYADGGSTSSSSSADGSTTEAPSSTGKPSVVSSTVAGGSTVIVTIQPTSDPQSTSSLDGGGGGGGDGGTNTAGIAAGVVVGVVAFAGLIAGLVFCIRRKKQKEAEEEFRQKNQVSDFMRGSNERKPPGTGYSGLSDQRLDPEAGARRNSVGSLADNQDYSRRILRVANPDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKD4</accession>
    <name>A0A9Q8PKD4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768388.1">
        <property type="nucleotide sequence ID" value="XM_047911845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKD4"/>
    <dbReference type="GeneID" id="71992575"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12697"/>
    <dbReference type="OMA" id="SHTTHAC"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="24234" checksum="0CA85949406F684A" modified="2023-09-13" version="1">MAPPGLLDMPPEICNIIYGSYFARRDNHREYEADLCLARPPSADLTAVCSQIRSDTLKMYLKACERYWKEIRFFIDTRESQSMDAEEAALKALKTQPYFEAIQHLELHNGSVDGLDLTSIVYRMTTEPGIWTYSVDHLGPFHFSHTTHACVYHTEPLENRKAGYRPLTSYDSVDEARQTLADIDPKLRCTRYEEIVRFLQDSFVLPQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKM6</accession>
    <name>A0A9Q8PKM6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13727</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768523.1">
        <property type="nucleotide sequence ID" value="XM_047912875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKM6"/>
    <dbReference type="GeneID" id="71993605"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13727"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="396"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="834" mass="90967" checksum="47FD711D245A2E5F" modified="2023-09-13" version="1">MKYQDFDAEETLAKLTITEKTSLVSGTDFWHLAGIPRLGIPAIRTSDGPNGVRGTKFFNGVAAACLPCGTALGATWDKDLVQRGGELIGKECIAKGASISLGPTVNMQRSPLGGRGFESYSEDPVLAGHCAAAAVRGIQSTGVAATLKHFVCNDLEDKRMSSNSIVTERALREVYLLPFQIAQRDAKPWAYMTAYNLLNGLHCSENPKLLQDILRKEWGFDGMVMSDWFGTYSTTEALKAGLDLEMPGPPNLRGQQISLAMSCGKVLRHHLDARVREVLKLIKKLLPLQVEENAEETTIDSPETAALLRSIAAQSLILLKNEDSVLPYKKDKTTAVIGPNADFAAFSGGGSAALLPYYAVTPLDGVKSKTQNIQHELGAPGWKRLPLLSRVAKTNTGKSGLIMKFYLEPPIKSNRTAIDELHIRDTSIFLFDYKNPQLRTHLFYADVDCTFTPDETAEYEFSCSVAGTAKIFVDGKLVVDNMTKQRPGDSFFGIGTEEEIGSIQLEAGKDYAVHVEFGSLPTLTYKKEGVTAFGAGGVRLGCHRKVDTKVEIERAVALAKKVDQVVLCAGLNSDWESEGYDRDHMDLPPGSDELIEAVIAANPNTTVVVQSGTPVTMPWASKAKAIVQAWYGGNETGNAIADVVFGDVNPSGKLSLSFPKRNEDNPAFLNYKSDDNRVIYGEDVYIGYRFYEKTGREVLFPFGHGLSYTTFDTKNLAINATDDSDEITVTVDVSNTGKIPGSEVVQVYIAPQSPSINRPKKELKGFGKVFVEAGKTEKVEVKLLRKYATSFYHEGKDAWLSEKGKYTVLVGNSSANTSLSGELEVVKELVWKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL69</accession>
    <name>A0A9Q8PL69_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Myo-inositol transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13697</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768906.1">
        <property type="nucleotide sequence ID" value="XM_047912845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL69"/>
    <dbReference type="GeneID" id="71993575"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13697"/>
    <dbReference type="OMA" id="ETGWRWM"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005366">
        <property type="term" value="F:myo-inositol:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904679">
        <property type="term" value="P:myo-inositol import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000073">
        <property type="entry name" value="MFS myo-inositol transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="48"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="546" mass="58518" checksum="076402CDB5E21017" modified="2023-09-13" version="1">MRREVADGHDAHEPLIRGSEEDLHHHDGDPGPTPNTSIRSAAPIVKFLTLSAGISGLLFGFDTGVISSTLVSIGSDLSGRPLTTTHKSLITAVTSLLALISAPFTGVFADKYGRKSVILVPALLFIVGALVQAIAQHVSVMVAGRALVGAAVGVASGAVPLYITELAPAELRGRLVTVQSLFITGGQVVAYLIGWGFAFLPHGWRWMVGSGAVPGLLQLFLIAWMPETPRWLLQTGQDGEARSVLNEVYAGLPEHDRALIVQNVLVSVQAEITAEDKAHSRSDSASGSSRFRDATKDLFAVPGNRRALIIACMLQGLQQLCGFNSLMYFSATIFSLVGFTSPIGTSSSVAVTNFALTLVAFNLIDTVGRRNILLRSIPFMVLGLLLCAVAFSFINMGDASAAGDVYNPNASSVWSIVLLISMIFFVASYAIGLGCVPWQQSELFPLRVRSLGSGLATATNWSSNFIIGMTFLPMMGILGASVTFTFYAVVCFVGWFLIWKIYPETAGLELEDIGELLKDGFGVQRSVREFQDRQRTKVVQSTVAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLT0</accession>
    <name>A0A9Q8PLT0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13559</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769148.1">
        <property type="nucleotide sequence ID" value="XM_047912707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLT0"/>
    <dbReference type="GeneID" id="71993437"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13559"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="3">
        <location>
            <begin position="96"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="240" mass="27283" checksum="9DF6152DCC2D10A1" modified="2023-09-13" version="1">MLRTTRLTQVFRQTPLHEVLSRASVRRNAAQLPKLPAKTTPRRDFATSNLRLTNSQRLIRAWRQPAFRSGRQARYNSTKTSAEEELGSNAPQSLSERMKAMSRKYGWIVVGIYLGLSVLDFPFCFLAVRWFGTERIANLEHAIIDGFWSQVEKFAPSLKEKREAKEAIAAAEEAAREGSDAVMKEAKKEGDASIWTQLLLAYGVHKSLIFFRIPITLAITPKVVKTLRKWGWNIGKPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMA2</accession>
    <name>A0A9Q8PMA2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769521.1">
        <property type="nucleotide sequence ID" value="XM_047913397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMA2"/>
    <dbReference type="GeneID" id="71994127"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14249"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="330" mass="37581" checksum="A4481681291DA808" modified="2023-09-13" version="1">MNDSSLEIPLPEDDANALIILLNVLHYRNDQVPDALCTHDLVDVVNLADKYLCKDRIQLAARLWVRNMEAVTDALKLARSLTVCRQMEFDGKFSTICRRMLLYSTGEAKLDSDECQYGNLEENFKLAFEMLQSDKEYRFYKIDQFIKTTIKTFIWARRSHPNNTCDSTCHVAELATYELFDLLRTKHLEPDFLSCFELYIVLDAMKTMPQFPFSHRYQPCSSGCIYDELEKKMAAGTFAAKAEELTAPTKPLCLAGYRVHGDVWGGCCGLKGGVARCRHCDPTLWGCGCCGVCVHAARQGYSREGERLAEEDVEENVEWTEAARARCEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMG1</accession>
    <name>A0A9Q8PMG1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_14498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769496.1">
        <property type="nucleotide sequence ID" value="XM_047913646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMG1"/>
    <dbReference type="GeneID" id="71994376"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14498"/>
    <dbReference type="OMA" id="MIPRWIN"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040493417" evidence="7">
        <location>
            <begin position="17"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO25130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="36139" checksum="F3A296F74E08D4BC" modified="2023-09-13" version="1">MPIFGLTLFIWALVAANGFGPTFSRPTRITDGTPVVVVFFQCVTTAIGPKATLALNMPDFTRYAKYPRQVFWTQAVGLMVLVTMCGVLGATVTSAAGVVYGVSAKQAWNPLYIATLWNNRAAQFFAGLCWAFAVVGTNISANSVSFSNDLSLWFPRYINNRRGACVCATLSIAAVPWYIQYSANSFSSFPTGYALFLGALAGILVCDFWIIRQRRLSLAALYTASHDAPHWFWHGINWRAFVAFMCGIAPNMPGLAKACNGALAVPKGASYLYSLSWLVSILISGFVYWACHKLSPMPISEDEVVEGVGSDVEVQSTEHHHSKSIDGKTAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMN1</accession>
    <name>A0A9Q8PMN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769543.1">
        <property type="nucleotide sequence ID" value="XM_047913682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMN1"/>
    <dbReference type="GeneID" id="71994412"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14534"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="30494" checksum="85E1840487755D5B" modified="2023-09-13" version="1">MRFLDSLRRICARLYMPDLLAELQTIFHIFDLNRATMIHRSSLLATALALTVTVVAQSIQCDCKARPNWGDCYTLIEPYLVNPGTFPAPGKGKGSCSTFTFPDNSLNCQVELCPDEDIPIRTSRVQLAYSILMATCDPNGAGGTYITPDPDGFRFTAELNPDFAVEPPSAVAFNATQGTHAKDIFKRQQDSVTSFELAATYKRITRPGSIYDVGPVIPGGGSITKTVETSETHSVSAGVSFSAGVKEIFSAGASVEVMDSYTVSNAMGVEVTLNCPANARKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMQ2</accession>
    <name>A0A9Q8PMQ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769737.1">
        <property type="nucleotide sequence ID" value="XM_047913657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMQ2"/>
    <dbReference type="GeneID" id="71994387"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14509"/>
    <dbReference type="OrthoDB" id="4177236at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="183" mass="20919" checksum="03948DFA14E4845C" modified="2023-09-13" version="1">MDFVDGVCLEDAWDTMHAEARKSLASQLRGIISTMRAATPAPGPQLIGACDGPARDCRYISDYTGGPFERETDFNMFILDLGKRTPRLVRETLEDSLHARTGHRILFSHADLSPRNIMVRGGQIVALLAWEFAGWYPEYWEPVNFFDRPTSCKGWHHLAIDIFETRYPTELLTHQAIARWQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMU6</accession>
    <name>A0A9Q8PMU6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Octanoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_14246</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>octanoyl-[ACP] + L-lysyl-[protein] = N(6)-octanoyl-L-lysyl-[protein] + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="5"/>
    <dbReference type="EMBL" id="CP090175">
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        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
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    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LIPB"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="9">
        <location>
            <begin position="39"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="156"/>
            <end position="158"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
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        </ligand>
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    <feature type="site" description="Lowers pKa of active site Cys" evidence="8">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO25297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="26527" checksum="E31E573F9A097B7C" modified="2023-09-13" version="1">MILRHLHLPYLTSYLHADKLQQTLVSNLLAHKASPKTVPPPQPTIITAQFHPVYTCGRREVGNLSRDQIDYLTASTPHGTASFHEALRGGQTTFHGPGQLVVYPIIDLKRHNLSPRCYVNYLEQCVIDILKSGWNVQAVRTDNPGIWTDEEHKICALGVHLRRNVTSHGIGLNLSTEMGWFERIVACGLEGKKTTNLQQMVGRGKTVDVEWAARSFVRRFGDGLEGSEAIEKIGEGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URE8</accession>
    <name>A0A9Q8URE8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase phnB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
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        <property type="protein sequence ID" value="UJO19734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71990239"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
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    </dbReference>
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        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="110"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="300"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="403" mass="45420" checksum="D10906591F280F95" modified="2023-09-13" version="1">MQVLIIGAGCTGLLLAQGLKRAGINATVYERETPEYCTGRPREWGMSLHWGIEAIEKVLPEELRARIREAWCDPCWEGELVLKHYHGHTGDLAFETQLGDGTRVSRRKMRELFKEGLDVRYGKKLATIKQDESSVTAIFEDGTEATGALLIGCDGARSVVRELLLGHERAQNTFLDVSLFNFPCSFDAEIAKRIRAQHPIFFNSYQPEGWMFWLSAQDVADVDKPETWLFQLMFSWVGPPRQEELATKEARTAFLKSKASLYVDPWRTVLQAIPDDVSFGLDRIAEWKPFDWSSEPLASRVTLAGDAAHAMAPYRGQGLNNGLEDAACLKELLANMQDATQALGPSLHQYEAEMRQRSLKEIEISRASAYISHDFEQLMNGPLAKHGVRKNVDIDEKPKDNHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USB5</accession>
    <name>A0A9Q8USB5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764972.1">
        <property type="nucleotide sequence ID" value="XM_047910018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USB5"/>
    <dbReference type="GeneID" id="71990748"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10870"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="28214" checksum="9A193C01C2BFCBE2" modified="2023-09-13" version="1">MAAETIAQSLDDLASALQTDRLIKLHIGNQERPYNIQQLFLVNCSEYFAKALRDNQFAEARSGTFRLLEDREDTWKVLLYWMTHRELPGDYIKNDLLLAVRCWILGDKYDIKLFQDDVMLMMISYGAETSSDPTPEMVREVFYNTPPGSKLRDFITEESVYLFEPGVRSDRLGDAVLRKNIGELDETGFLPLYTEKKREYNAQGGDPDWCDRFRDGCWKRYLRGPAERYQGWALDTADCMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USR8</accession>
    <name>A0A9Q8USR8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765406.1">
        <property type="nucleotide sequence ID" value="XM_047909952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USR8"/>
    <dbReference type="GeneID" id="71990682"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10804"/>
    <dbReference type="OrthoDB" id="3856067at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="27305" checksum="D2BEBEAFBFCD51B6" modified="2023-09-13" version="1">MATTTTPSNTAALRTFGVTELLEQILSDLDMQTLLLAQRVSKQWKDTIADSSMLQEALFSRLQTTHRNIYHGHGGENSFVSLDSSFSRPLVYYNDTFVVTFSYEQFKPNELRLNFRVRTRDYWGDIFGPFGEMTELDGGPKPSWHRMYLLQYLSPAAMSWNCYHAVFQMEVRGVKKLKEFEEEWHEFDWDQKPLASICEDAIKITSQRVLQDMLDGNVTATYYDTLTPYFGAVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USY2</accession>
    <name>A0A9Q8USY2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765705.1">
        <property type="nucleotide sequence ID" value="XM_047910634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USY2"/>
    <dbReference type="GeneID" id="71991364"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11486"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20914" checksum="6B9A5B1531BB0FCD" modified="2023-09-13" version="1">MQFNSTIATDRMHVLVESKLRNEIARKDRDLRRMLGHFDMLERVNSQKHMHLAVHSNHDSGNRLPQSAHFETSSLHVEDAALIEHEERPRHEEWPKYDKDMVVIESVEVDGDEDLATSDDGSNSDEDELPDYDDVSGSDLVRIQDENHHSPPSLVEDALNDLNKLALQPSFEENTYEVSEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT66</accession>
    <name>A0A9Q8UT66_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765945.1">
        <property type="nucleotide sequence ID" value="XM_047908466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT66"/>
    <dbReference type="GeneID" id="71989196"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09318"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040509233" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="72"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="526" mass="57512" checksum="011EBB0BAD4B315F" modified="2023-09-13" version="1">MVLTTVFRLVPLLSAILAPVLAAPSPNAVAACGVIERQYPAQYADNGLINSNISVGLVHTQQRQEYWSLANADNKPACMFFPKNAKDIAFAVQVLNNYTTVPWAVKGGGHNPNRGYSSSQDGVRIACEPNMKSTTLDANNLAHVGPGSRWTDVATALDPYNRAVVSGRLGHVGVASLSLGDGLSFLSTEYGLTADTIAGYVVITADGVIRNANKNENSDLFYALKGGGNQFAIVSEFILETFAIGQVWGGTKIFGKDQKDALLKATHNLVSDYYDPKAAVIVTFSTTLDTLVDIFVVFFFYNGPSPGKILDELNAIPALIDSTKGPRSYRDLINANSAFSLNGMRYLIRTGTFPRLPGADGLDIYNYTFDSWYDAAKKYQLTQLDNLIYSLAFQPIPHQLAAASKNAPNGVNLLGLDPAYGDKFFMEYDVSWLVAPTDKYAADSITQMTQPAQDYARSKYGNSPPTNYQSGDLSFTNFNPMFMNDAMYNQQPLQSYGQGTYQRLKQIQQQRDPKGLFSRTGGFKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTH4</accession>
    <name>A0A9Q8UTH4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766184.1">
        <property type="nucleotide sequence ID" value="XM_047908465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTH4"/>
    <dbReference type="GeneID" id="71989195"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09317"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="38192" checksum="E0AA8F56DE091313" modified="2023-09-13" version="1">MASTAAMTAVFGTTELLEDILITATLQGMTHEELLLAQRVSRDWKATIEGSPLLQKLLGFRAATTDQDFEFLYQWSQRRLSLGDLSSQTRELQFAEQNGRSVTFDVFVSPLVSRVLDDWPLDFPIADKDGTRDSRDLCSDVALRSYKGYLANTFTYFSSERTRRQDLDKHHFMKTGPMRVRFEKWNKIESSMHRMLLTQPPPTSANLEYDDKHGEDKIKIVKSPTGVKLGGIWLAGMEVDTPYDQKKACWVEDEYGYDSDIVDKLKNFWAQKGEVYDGEDSDDSNVSDEDSDEGSEEDWEDYYGGDWSSEASEDDWEDEDSEDNDLEGWGSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTH6</accession>
    <name>A0A9Q8UTH6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766171.1">
        <property type="nucleotide sequence ID" value="XM_047908787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTH6"/>
    <dbReference type="GeneID" id="71989517"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09639"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000007">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000035">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="530"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="576" mass="64591" checksum="DAD78063936FBE07" modified="2023-09-13" version="1">MQPFITTPGHGPYTGFSDGDTSTYIQDYVQASDSTTTNGKMPSFEEAPSPKGRLLLISNRLPITIKRSDEGNYAFSMSSGGLVAGLSGLAKTTKFQWYGWPGVQLPENEIPHVKKRLDEEFNASPIFMEEELSERHYNGFSNSILWPLFHYHPGEITFDESAWDGYVEANRLFAKEIAKDVQDNDLVWVHDYHLMLLPAMLREEINKAGENKPKNVKFGFFLHTPFPSSEIYRILPVRNEILQGILHCDLVGFHTYDYARHFLSSCARILGLPTTPNGVEFQGKLVTVGAFPIGIDPEKFVQGLQKDNVKDRIESLKKKFDGVKIIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGRVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFMHKSVNFDELTALYSISDVCLVSSTRDGMNLVSYEYIACQEERHGSLILSEFAGAAQSLNGALIVNPWNTEELADAIHDSVTMNDEQRSINYQKLAKYVNKYTSAWWGESFVSELTRISEQAEKKLKVRRQSTVDGPDVSLTDGQEKSSEHPASAANGVNNQAVTSASGEADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTT9</accession>
    <name>A0A9Q8UTT9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766592.1">
        <property type="nucleotide sequence ID" value="XM_047908961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTT9"/>
    <dbReference type="GeneID" id="71989691"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09813"/>
    <dbReference type="OrthoDB" id="4252443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="46163" checksum="8FFBA6AB962F119D" modified="2023-09-13" version="1">MTLVSRTWHALSIPYLLQNVEPGSHNHGQLVPFLGSMEILEMDHSGILIRQRTFLRLMTAKPELARHVHNLTWTFFWQDENEKGPTALDRETWNVFSRLENVTSPDLAQYTNVDACHDPLVRQNPPRMFPRVTSLRLEGWMHRRLVTAIMTSICPSKLRSLKLDGLNDEGLLPDGHSMVVQIERQYARDISRARPGDLSPFDDDMVQRQKLGSACSFSGPTWYPLRYLAGFRLDSLSTLDVQLSPLSGRDDRNYLTLFQGVADVLRTARQSLTFVRIAFGESPQHHGPISSGCGNARAGWVRYQPQCVAMASIFSLYVLPVLCDEHFPRLAKHDCEGFRLIKDLGGDPRNLERGDSIREYQQALLLPDVSIMAKACVDYRWIGQHGISDHHPHPESLGQVTNIFLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU37</accession>
    <name>A0A9Q8UU37_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450-DIT2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766920.1">
        <property type="nucleotide sequence ID" value="XM_047910951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU37"/>
    <dbReference type="GeneID" id="71991681"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11803"/>
    <dbReference type="OMA" id="FIPGRWG"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF223">
        <property type="entry name" value="CYTOCHROME P450-DIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO22554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="18948" checksum="A8A5ADFADF6FB6F3" modified="2023-09-13" version="1">MGVQTDRPTSDQLNDLLHLTTCITESLRLMPPIGQLINRLATSSLTLGEDHVVPEGTYVGYNSYATNCDPDVWGKDADEFIPGRWGETIEEVRKQYRRQKARAELIRFHGGRRACLGEGFAMVELKVTVFMLVRWVRWSLDEEWEEKMTPAGPLAPRGLRLVFAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUC1</accession>
    <name>A0A9Q8UUC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_11930</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767160.1">
        <property type="nucleotide sequence ID" value="XM_047911078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUC1"/>
    <dbReference type="GeneID" id="71991808"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11930"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000047">
        <property type="entry name" value="Mannosyl-oligosaccharide alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040118943" description="alpha-1,2-Mannosidase" evidence="15">
        <location>
            <begin position="21"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO22794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="606" mass="66714" checksum="C6E867DA6DE5D770" modified="2023-09-13" version="1">MAVCARLSLVLHLLFSTVVSTELGNEAIPAYVQPNTDTSPAKPDGPIVPDRSKPTVTVTLSRAHPPAQTIFVQPVPVEGCKKVQAAGVKGDETRAEAIKEAFRHGWSGYSKYAYGMDELQPLSAKGNNNRYGWGLTIVDSIDTAIIMGLNDIVSDMLDFIGKIDFTRTRADHINVFETNIRYIGGLLSAYDLLKSGQFSGNYDEDQVDALLEQAVTLTDRVAHAFDTRTGLPAADLDYNNGRPITATYTDPSNNATYNSTNAASIGTFILEFTRLSDLTGNQTYRQIAERANSYLIKPSPSPIYPGLIGTQFDIDTGEMLTFDGGWQAGVDSALEYLIKTYQYHTTNTTTTYKDFWLKAVESTTENIAVHPYGFPDLTFVTRLDNNGSLEYLADTFSCFAGGNFLLGGAFLDSPDITDLGVAWTDGCHKSYNSTLTGLGPLAWAWFNETNQAYDADNENDAAARKNAARKGFWIFPQVENWFSRPEPLESVFYAHRITGDERWADHNWEIFKALNETSRNSIAFAAVNNVDMPDGGSLSDSLDSFFFAEVLKYLYLTFAEPDVIDLSEWVFNTEGHPFRATCAGGASSSHGSAHVHGRRHIHGLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUQ0</accession>
    <name>A0A9Q8UUQ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S-(Hydroxymethyl)glutathione dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767537.1">
        <property type="nucleotide sequence ID" value="XM_047911101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUQ0"/>
    <dbReference type="GeneID" id="71991831"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11953"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08283">
        <property type="entry name" value="FDH_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="68"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="448" mass="49272" checksum="AF88CB6EA40B029F" modified="2023-09-13" version="1">MALSQAAAQLEKVIGHGDNATTEQNLTNPDRNREKYADPSGEKMKALAWMGKNTVEMIEVPKPRVVEDKDVILKITGSTVCGSDLHLLHGSVVVLEKGDILGHEFCGVVDSVGSAVTNVKKGDRVVASFQIACGDCYFCEQKLSSQCEKTNSNTIENGMYGGRTAGMFGYSHFTGGFAGGQAEYTRVPYGDVNLLKLPDDVPDEKGLYLSDVISTSWNCVVDTGVKEGDVVAVWGAGPIGQMAAEFSFLHGASRVIVIDSNWRLDYMKEKYPRVETVDFSQLKGTKAVVSKLKAMCNNRGPDVALECVAGEYPKGWFHAAQITLGLETDTSEILNEMIESVRNFGRVGITGVYVGYTNNFNIGSLMERGIRFIGNGQAPVHLYWEELLKRIQSGEIDPLKMVTHRVDIEDLAKVYYKFEKKEDHMQKVYVQTKFSAPPCEGSPALTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV05</accession>
    <name>A0A9Q8UV05_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767867.1">
        <property type="nucleotide sequence ID" value="XM_047912343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV05"/>
    <dbReference type="GeneID" id="71993073"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13195"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="72" mass="8162" checksum="CC8790F6B54ADF8E" modified="2023-09-13" version="1">MNNQGMNNQQPAGQKEDYLDKAVDAIEKKFGQASGHQVDPAKYRAQNEKFTDKLRGFIEKKTGKKMPSKFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV64</accession>
    <name>A0A9Q8UV64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767913.1">
        <property type="nucleotide sequence ID" value="XM_047911702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV64"/>
    <dbReference type="GeneID" id="71992432"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12554"/>
    <dbReference type="OrthoDB" id="10569999at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="81" mass="9238" checksum="CAA262E1110B33F7" modified="2023-09-13" version="1">MRQHGLIPYTKPQLLTLNHHLLTLGYLDFKAAAERKTLLTLPGEIRNKIYELVQEQCAVATITWTTPLTLPARLAQVCRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVN1</accession>
    <name>A0A9Q8UVN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Maltose permease MAL31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13835</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768509.1">
        <property type="nucleotide sequence ID" value="XM_047912983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVN1"/>
    <dbReference type="GeneID" id="71993713"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13835"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000149">
        <property type="entry name" value="MFS transporter, SP family, general alpha glucoside:H+ symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="63"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="60170" checksum="2F410311876DB768" modified="2023-09-13" version="1">MNFLEQQHEKQPATHDEVNEKGHPATSSTKVADIALDAKDATDKEHAMSLRQAIKLYPKAIAWSMFLSSAVAMEGFQLILIASFFAFPPFTRKFGELQPDGSYEVTAPWQSALSNGARVGEILGLTIHGIIAERYGYRITIIGTLMSMIAFIFILSFAQNIGTLVAGEILMGIPWGVFQTLTTTYAAEVCPVVLRGYLTTYVNLMWAVGPLGFLQRSDQWAYRIPYALQWMWPPVLLIGTAFAPDSPWWLARRSRYDDAKKVLRRLTSAASETDLDQTVAMMRHTDELEKEVSIGTSYWDCFKGTDLRRTEIVCVAWAIQPLCGASLMGFSAYFFRQAGLSTHVSFDFSMALYAIAMVGVIIAWFAIHRFGRRTLHLAGLTAMCLVLLIIGFVALAPATAKGPNFAIGSLLLVWALCYNITVGTITFSIVTEIPSNRLRTKTVVLGRNLYNVVGIINGVITPRMLNPSAWDWKGKAGFFWAGMCFLCLIWSYFRLPEPKGRTYGEMDALFERKVSARKFKTTAAELFSAAALEKQAPKVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW20</accession>
    <name>A0A9Q8UW20_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768932.1">
        <property type="nucleotide sequence ID" value="XM_047913012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW20"/>
    <dbReference type="GeneID" id="71993742"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13864"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="377" mass="43054" checksum="A03AE4C8854B300D" modified="2023-09-13" version="1">MPRHDLPRVDGLDRTEADDCWLQSTGIEDLDVLYELTACRRRCDYLDSLTLEQVRAYRSLWDPLLMAVLGYSSRQSGPLYEPGILNQSTVWWVLGQLHRHGPLLFWNTWKLHNEHERRDKCAIKHFLEESWHERDNAGADHLSDSMILLWNEAAVDTYQRLKVNVMTTHSRHSEERRRILRDPNPSDARKQRKESTRLGGPSPATAMSDVPFEQKLNCDIMGEQPWEERPSGRRLRGCYGVSIRMAFASPCDPSAQPNTEEFKQLRSQVRKARYGAFGLQPPSEVDGMSFDSTAWANEDAAFESSVHEFDMGDFTPITGNHPLAETRASDRKVHQNTGTYASSNKTFNSRSCITTHAVKDTAGPRCTSSNNLTFLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWL3</accession>
    <name>A0A9Q8UWL3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769502.1">
        <property type="nucleotide sequence ID" value="XM_047913454.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71994184"/>
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                <person name="Chen L.H."/>
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    </evidence>
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    </evidence>
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</entry>
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</entry>
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    </dbReference>
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        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glycosyl hydrolase domain"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
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    <keyword evidence="5" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="20"/>
            <end position="447"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO10932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="606" mass="69908" checksum="B13272994F718460" modified="2023-09-13" version="1">MTLMQQANAHRWWKEAVVYQIYPASFLHTGAGAQPGWGDVQGILSKLDYLKHLGVDIVWTSPIYMSPQADMGYDISDYKNIDPKYGSLEDVDDLVAGLKQRGMKLMMDLVVNHTSEQHAWFLDSRSSKSSKHRDWYIWKDARKDDDGNRQPPNNWSQILGDANSAWTWDEKTQQYYLSLFTPEQPDLNWENPDVRDAVHDVLRFWLDRGASGFRMDVINLISKDQRYPDAEITNPKAKYQSGHKFFANGPRLHEFLKDMNQKVLSKYDSITVGEMPYVTDEKEILRVVGEERKELNMIFIFEIVDVDNAPGGPRLTLHEWTVDDIREIVSKWQNVMRAQGGWNSVFIENHDNPRSVSRYVSDATQESRELGAKLLATMQTTLSGTLYVYQGEEIGMGNVPLSWQPEEYKDIESINYWKKMSELCKDDDKMLDFAKEVMQKKARDHARTPVQWNDGPNAGFCESGIKPWMRVNDDYKIINAKAQWELDDPGKLSVLQHWRRALENRKKEKEVFVYGDFKVFDDKHETIFAYRRASKEKAFVVVLNFSDKQVEWQVPQDARVQKWVAGNYTSGAPGQDVSAATIQLKPWEAILGAAHVDKSLSIHATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L556</accession>
    <name>A0A9Q8L556_PASFU</name>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </dbReference>
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    <dbReference type="GeneID" id="71981599"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01721"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="87" mass="10255" checksum="C405278B6B0E6350" modified="2023-09-13" version="1">MSSTISDCDRYIPAFELYDFKLVETVIRNSNVVYTVIVVGRNHDLERPVIRHSIGVSRQCRYLRWASEYVCINHRAARPDQCYFRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5X5</accession>
    <name>A0A9Q8L5X5_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Aurofusarin biosynthesis cluster protein S</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">CLAFUR5_01272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YLR001C"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="279"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="52348" checksum="D1FF2AA704CA6ABF" modified="2023-09-13" version="1">MKITNVLPLAALSSAFVLPQEEVLATLAIEDHHGHTSVDSLVEKASAAKDDVLSSFKKHLDEFTETSKNVWEELSTDVQSGLDNAFEQAGDAASLFGDKLSQVSDDVESWFEDTIEAVEDHGHRPHKPPHHHEPNETIYQLIAGSKYTTTLAKLISEYDDLVDALNTTAANFTVFAPTDTAFEKIPDKAPKPSKEQLKAILQYHVLPGLYPAGHVLAMHTAPTLLVGEHLSSQPEPQRVAFKISLRGLTVNFYSRIVAINIAATNGYIHGVDSLILPPPNAIEIVDLFPGEFSTLELGLGKTGLLEKLNTTEHPGGTLFAPSNFAFQKLGPKINAFLFSQYGQKYLKSLLEYHVVPGTTLYSDAIYQAHKHDNVDAEQELPRKGLFHIDLPTFLKDRSLSVDIDRYGGFISIKINGFATVSVQDAIAQDGVIQVTRDVLIPPKKIGGAELEHWDGSELTVEDLKQRLEPFVAKSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6F1</accession>
    <name>A0A9Q8L6F1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcription activator of gluconeogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00689</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERT1/acuK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756087.1">
        <property type="nucleotide sequence ID" value="XM_047899837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6F1"/>
    <dbReference type="GeneID" id="71980567"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00689"/>
    <dbReference type="OrthoDB" id="2538135at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF1">
        <property type="entry name" value="TRANSCRIPTION ACTIVATOR OF GLUCONEOGENESIS ERT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="11">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="538"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="700" mass="76739" checksum="6BC8C18D13BBDB04" modified="2023-09-13" version="1">MSPDAEDASPSPEPGPEQDESGIMAEEKIERASTEEKSPNAQASNGNTQPSKSNAKDPSRPRRKKARRACFACQRAHLTCGDERPCNRCIKRGLQDQCHDGVRKKAKYLHDAPAEALMPGYAQNYAMNGSQNLSTVAGASAIGPNGMAVSQPGTFYPQSSAGSFPPYTPSQQQGQMGPPIMDNSSMVADFTSTQSVDTPTQYQSTSSQQVSPAQEMANAMEHTPSIGTGGPSFETYFDPNDPSLFNFNISDLNFGNHYGALEFGMLGHISSGAVNTPEVDQMNSISHSNQGSVSYEGSANYDSNTNYNYNQAFPSWSQAPGAGSRHNSGNNLWTPQNNGLEAYAIAEQGSSITTASPHSQSQDFLRFQSSTLSPETQFAQPEQHQQSDLLRQSLSQAQRKPPAFPGDPNAELKKPRRNTSEIYTSVQAPYSYTQGFHALTAFLQKRYPKNKVLRIAKALANIRPSFISCNQRLNQDDLIFMEKCFQRTLCEYEDFISHYGTPTIICRRTGEIAAVSKEFCLVTGWRRDVILGREPNLNVNTGGTSSGTQTGASSRGVATPRMPNVDLDPGRPQSVFLAELMDEDSTVQFYEDFSDLAFGATHNSIIGATCSLLKYRTKEDPGWGPNDHLTDDGKRIKNPGEIKSEPLIRGEAGMNALGERDGRVECQMCWTVKRDVFDIPMLLVMNFLPIICYPRHGHSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6N9</accession>
    <name>A0A9Q8L6N9_PASFU</name>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Fulvia</taxon>
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    </organism>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6N9"/>
    <dbReference type="GeneID" id="71980429"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00551"/>
    <dbReference type="OrthoDB" id="2151982at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21630" checksum="07F69469D02A92C4" modified="2023-09-13" version="1">MLVHCDSQQASCSFTCSKGWPAKSYTLSHRIQSCFLMSAVASLRHCSRLEKLGCHERLRLSLAGSGLLEELLYQKTNGKIKIHGVEVPSCRSVYLPEDRMLRVPSTTSLHPDAILADTLLFCYPRQSSLIREYVDQFGSGALAQIVLVVNHNDWKDMAKILHDSFSTIEIVESAGLPEYEVLVVASVPRGRHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Y0</accession>
    <name>A0A9Q8L6Y0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rrn9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756272.1">
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    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Y0"/>
    <dbReference type="GeneID" id="71980302"/>
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    <dbReference type="OMA" id="WTAWPLK"/>
    <dbReference type="OrthoDB" id="5412288at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019622">
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    </dbReference>
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        <property type="entry name" value="RRN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="140"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="51"/>
        </location>
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            <end position="360"/>
        </location>
    </feature>
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            <begin position="469"/>
            <end position="572"/>
        </location>
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            <begin position="7"/>
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        </location>
    </feature>
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            <end position="43"/>
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    </feature>
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    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="572" mass="64597" checksum="A05879189A6DA3C9" modified="2023-09-13" version="1">MSSIDADFDRADEHTHDDLESEEEPDREESHADDDLSDDDRPGRFYGPDSSWRFYTQKERALAASLDQAENNDLSIHLYNAHAWKQQQRDEQRMVEARPWHSKQQWIKPDEEGKLPFLPPQAWTAWPLRPEHVPRSTEQWGVPATAADEDADTLRAPESWKPSLHLQEEVKATILRLAKERFHAREWAHAHQTEFVKAEPTKRPMRSTSIKPEYDSDEPLDDLDRLEKELQQEAPPDPGESSEHYTPMVLDDEDAASRIVQPSVRHILGKLDNLFIALHKSRRGHRKEPGGSGRRSRSSRSQSQARARPQSSGNAARKRKRVVSDPHQQGNDGEVEIKFSSDDGEEGEKVSHGSSSKSALGTRDWSEILGVAALVGFDQTVIDRTARRCATLFREGMTLRTMPEVLAGTAHDHTTDYIPDMVPPIASESDEDEPDEPMGDTIHVYACPDVDCARHDRPFEQRWRLSEHLKRKHGHTDEELATETLKLSPSARTSPSNDSDGDNDSSASAEFDSGERGPILNGSSDGRDEFLKPISVHIGRSRDKRARKARSRSSGPNSRTGRRNSIVDMKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7C5</accession>
    <name>A0A9Q8L7C5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71980341"/>
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    <dbReference type="OMA" id="WKDECAG"/>
    <dbReference type="OrthoDB" id="5429993at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
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    </feature>
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            <end position="153"/>
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    </feature>
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            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="57599" checksum="5AAF50A73C008ED2" modified="2023-09-13" version="1">MASGSRLPSSRPPASKARPMSMFEVPSHHMKKLQNLGDGDDIGDIDVPPSGASAKQAKRRSLLPTFSRKQSPDNDNERVGTIREDTSDSEVNTRAGAMDERKAMPPPPKPARPTSMRLPGSVPARTSSIHTRVPSKESTGTSARSNRAPTPSSGGAAKADNAIKRTGSTKLPQSPRTGGPAAPPAQQAIPTRGSSTRATASTTAQKRSSIAAKPSFADRPSSRSTQPSPAPASPPGQSSQRPSTRSSQMPPPSRPTFSTYQQHYSPAKSTLPKPGLPATKPAKSAAPASIEPDVPMTLDVALEQIELIQLSLVHEGAAQVMQAFEASAKSKLSKRHARLRKQYEDIRAHEQQHRRAVNLNALESWCPDAALMAEHLQTLSRIVTDLRAHTDPGSRHSELVETFDDWATKAEELLLNDQHPATFIEALPESWRAIHTSLALKLRSIQRDISVLPPPPPRHGADSPSSLETILENCSSLVDSMLKELDTMTKLQKEVLQRGKARIDEQINALMAAYQQAQGEEKGNWVPAWQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L863</accession>
    <name>A0A9Q8L863_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_01101</name>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900249.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8L863"/>
    <dbReference type="GeneID" id="71980979"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01101"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="733"/>
        </location>
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        <location>
            <begin position="51"/>
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        </location>
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            <begin position="89"/>
            <end position="101"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
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        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
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        <location>
            <begin position="467"/>
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        </location>
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            <begin position="495"/>
            <end position="504"/>
        </location>
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        <location>
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        </location>
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        <location>
            <begin position="688"/>
            <end position="710"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11948.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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            <authorList>
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                <person name="Chen L.H."/>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3624966at2759"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="45645" checksum="45E60888662FB937" modified="2023-09-13" version="1">MDFLLEYLLLTEVRDPDIARILRDSSTSTIHPVFQQRRWDGLSDDGFIFCRPALVLASYLLTCPRGLHFFHAFLFGEHTIHRDRHGMTRTRFDPVYDTQRPLPPEEEKRVLAALEEISNLIRVRFADTGRDDGRCQPGDTVWTDRFQCITSPLATRSTISISQRTLDRIQGQHLSGPAPLRCWFSLAVTLVHEFGHAIWYAAAEPETEGIFANQDFCEMGYAVTSWIVHGRPEISQLRHNGEEVLALRHIPNLSMVEIYRESGLFPLFRDLGPDNEMIGIVDDAWLKELFMGITSNKKFVADNGEGLRPTVTYCQCEDCRVITDTGSYPTHSIDSVDSADYATRPGCVAHAITRPDLDGGAASENIQWMLSLSQEGVEALRDPVFRTCVLALREKYPFHNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <name type="common">Tomato leaf mold</name>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71982273"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02395"/>
    <dbReference type="OrthoDB" id="3553147at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="19355" checksum="097654738DF2C67C" modified="2023-09-13" version="1">MLVAAHSTYYKCKEEDLLTKLGRCSELDCAEPRDRLYPLIGMDTSLSIVPDYSFSTAQAYTQLGKAMWEAGEGVCASDNLQYHRRASQAIGLPSWVPDLRFGFNRSQHVAAADLGGKVDQNNVLTYSPHRIGQVIKVSDHSHFVLETMTFEEDLEFFLKYTQSISKRLPLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L999</accession>
    <name>A0A9Q8L999_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_00344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71980222"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="84" mass="9537" checksum="8B17E14B2834F3BE" modified="2023-09-13" version="1">MADKLRTQQQLESLQNKYIGTGHADTTKHEWTSNIARDSYASYQGHPPLLHYMSIGMGMPMEKVRMHCMEKMVLPCGPAPAMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA10</accession>
    <name>A0A9Q8LA10_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02892</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757989.1">
        <property type="nucleotide sequence ID" value="XM_047902040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA10"/>
    <dbReference type="GeneID" id="71982770"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02892"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="301" mass="33318" checksum="5154579CDA757950" modified="2023-09-13" version="1">MGLYLGRTPVLPDAPNFNPPMLDEAAEDRPWAPCFRGEDDGPWPPMLSHSMSAFVNSTKLHVIVNDLFSTVYSRKVPADPLPYVQQTRQKLEAWRAASASHLIMLPGASHCPPVHIVLQNLLYYAATILLHRPFRNSAACRTACREAADEIQRITCLYEKNMGLSHVLYLMAYATYIAATVTLLMVHDGVEGARAKVDFFLHEMHACRSSCPAIQKSIDIIVKGPEPRPVRTATGMNTPAVDVPRADQHPLPAFPFEQQHQHMQPLWTGGDGGMGALPSGGLDPFALEWSQLPIDAFENFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAQ6</accession>
    <name>A0A9Q8LAQ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758396.1">
        <property type="nucleotide sequence ID" value="XM_047902600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAQ6"/>
    <dbReference type="GeneID" id="71983330"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03452"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="469"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="544"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="711" mass="76984" checksum="38A044E447BCE8B9" modified="2023-09-13" version="1">MEFDHTYNGAVDWTFPSPTATPTAGNFQQHVYQTPKTGTFQSHFNDAFSTPQMPGYATPHQPDYAIMTPVQGQQQMPADMDNYYANMQSNGTMLQHPAMPPPTQSSAPPAMVSPVYGYSNGQPVQPRAAMSFDTSQIQTPPPTRGSSVKKPTPSQFVAFGTPSTIASRRFASPQQVPAAIQPPQSQQQMPMQFPHLQFSPQVIQFANLGPQSAPIYPQTQIMWEQAPNPTMYSQQPRRLDDPFSPTTSGPMGWPTQTMQTSAAQTVSFNTPAMSSFPVQPPFERPASAAPVATSQQAPPIPAMTTASVDPSLVYSSPIRPVKSSNTKPNRPPITAPKSETKRKDSGNAEHKRTETTSSVDTVSTTSSTSKGLRRSNTTGTARPPSAPRANSSESLSRSSSTLQPPRTASPMKRVGRLPLGSISESRRITPRASVILTIDESGRARTVTQNVPSLVPSKSMLDKYQERFPGLFDSDTSDEEEDEEDQTPSRSASLSFARGEERKSKVAKLDPPVENLEGLSIPHSSSSASMKVTPSRAAIAAAAQLRRGGSLRKQTPSRNGQRRAASSAAATIDTAPMDMHSDRQHSIAGAQTPSLSLEWPETALDAHNRRWSVMSMDQPHSVSPTHQFPENPYAQHDLRRAAQPGRLLIRCTCGVPHDQGMVLVQCISCTQHTHAACVGLNPASLSNTFTCFLCTRPSSGLKVKVGSRTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB27</accession>
    <name>A0A9Q8LB27_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein bS6m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757844.1">
        <property type="nucleotide sequence ID" value="XM_047902895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB27"/>
    <dbReference type="GeneID" id="71983625"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03747"/>
    <dbReference type="OMA" id="HQIGDYW"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.60:FF:000007">
        <property type="entry name" value="37S ribosomal protein Mrp17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13185" checksum="4113A4777A34EAA5" modified="2023-09-13" version="1">MLYELIGVVRPGRSINEIKEITRTTGNIVLSAGGVVRGITNWGTFTLPKPARKQGATYKDGHYFILRFDSSAKTQHAVRRTLGLDPRMIRYSVVQLGSKLDEIKDIAGKANWGGVVGGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBI9</accession>
    <name>A0A9Q8LBI9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine amidotransferase DUG3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758580.1">
        <property type="nucleotide sequence ID" value="XM_047901956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBI9"/>
    <dbReference type="GeneID" id="71982686"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02808"/>
    <dbReference type="OrthoDB" id="14446at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061672">
        <property type="term" value="C:glutathione hydrolase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008242">
        <property type="term" value="F:omega peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000045">
        <property type="entry name" value="Glutamine amidotransferase DUG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="43784" checksum="EE20BA726AB622A4" modified="2023-09-13" version="1">MCRFLIYSGQSPILLSHLITSPTHSILTQSYDSRLRIDTTRPHNGDGFGVGYYTTAPAPRGRSLSNTHPSHSYAPKEEVVDLGPEPCIFTSTIPAWNCRNLERLASKTVSPLIFAHVRASTEGALSDSNCHPFSRGALMWMHNGGIGGWKLGVKRRLVSEIGDRWFEGIQGSTDSECAFALFLDCLDKAGVDPDDAVKQVDGFGHTVLRKAMLKTIERINGYIKSLPDFRKEEEDNFTSLLNFAVTDGKSVICTRYVSSNKNEAASLFFSSGTNWAEQPSATPNAKSKVGKGEYKMERRDKGADIVLVASEPLTFERDNWVTVPTNSVLTIHNQNVLIHPILDEYYNHTASFVRSTEFAADKGQTTGDGMAEKNSAQGAIARMSSVDGLADRGGGVAVGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC19</accession>
    <name>A0A9Q8LC19_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin reductase</fullName>
            <ecNumber evidence="7">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759018.1">
        <property type="nucleotide sequence ID" value="XM_047906989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC19"/>
    <dbReference type="GeneID" id="71987719"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07841"/>
    <dbReference type="OrthoDB" id="371245at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="4"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO14652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="358" mass="38583" checksum="BC7E8CDC95A571A8" modified="2023-09-13" version="1">MHSKVVIIGSGPAGHTAAIYAARADLKPVMYEGFLALGIAAGGQLTTTDEVENFPGFKMIKGTTLMDQMREQSEECGTEIVTQTVGKIDLSARPFKFWLNPMGDEETLEEETHTADSVIIATGAKARRLELPGEDKFWGNGVSACAVCDGSLPIFREKPLVVIGGGDSAVEEALYLTKKASKVTVLVRRDQLRASKTNARRLTTHPKVEVRWNSQGVEIKGDGGPKGLMKSLVIKNNKTGEQEEIPANGLFYAVGHEPATQLFKEQLKMDEDGYLITTPGTTETNVPGVFAAGDVQDKKYRQAVTSAGSGCMAALEAEKWLAENVEDVPNGIEGDSEVKKGKPEANGDVPEYRSNPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC82</accession>
    <name>A0A9Q8LC82_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC82"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="19370" checksum="FD350DECDEC3A738" modified="2023-09-13" version="1">MKAVKAYSHVDWFENEKGGDMDLGITFTNQPSRAPQRNPVRRKPFGAKFSDRGLSETPLRRLGENIEAVSPLSKADNGGSIQNLPESSTPQQPLSVQLPPPPKDIGEYQKFGDQGTLIKEKEDVVQFDPSKHPAPPQVAGNKRLRGDGDDNSEEHEAKHYKALIAQTFHLDPTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCM7</accession>
    <name>A0A9Q8LCM7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759295.1">
        <property type="nucleotide sequence ID" value="XM_047907079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCM7"/>
    <dbReference type="GeneID" id="71987809"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07931"/>
    <dbReference type="OrthoDB" id="5314997at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="110" mass="12684" checksum="FAFD588EFB6BDB31" modified="2023-09-13" version="1">MTTTTTKPFRFFDLPAELRNSIYALVSRSVWIRPLDTRAFFDVSMMGRHDSCTVRNLQLVSKQFRDEYEGEVGKDGTLELFVDQHGCTRRPFQSTIKQHLETSLAKAPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDF9</accession>
    <name>A0A9Q8LDF9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate-dependent dioxygenase oryG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_08578</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759738.1">
        <property type="nucleotide sequence ID" value="XM_047907726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDF9"/>
    <dbReference type="GeneID" id="71988456"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08578"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="45"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO15372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="369" mass="41371" checksum="3F5A7E647236899B" modified="2023-09-13" version="1">MASSQDALDHLVRANGHSDVHSTKHALVQEPLELGGHLKKYKSFKSTPIIGTEYPDANLAEWLTASNSDRLIRDLAITISRRGVVFFRAQRDLTDVLQKELAHRLGKLTGKPESSYLHIHPLSNFNDDKDLHINVITTDKAAAPAEDLWKNRPADIRNAWHTDAGYEPNPPDYSVLKLTKMPKCGGDTIWASSCETYDKISPAYRGFLEGLTATFSQARLPKVAAEKGFELYSMPRGSPSNVGTSLTTMHPVVRTNPVTGWKSLFAVGNHVATINDVTPDENRRLQDWFLQMIVEEHDTQLRHRWENEFDVAIWDNRTVYHSAIFDYAGLGVRTGHRAVGIGEQPYFNPNSLTRREALAKVADGGWADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDR3</accession>
    <name>A0A9Q8LDR3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759179.1">
        <property type="nucleotide sequence ID" value="XM_047907068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDR3"/>
    <dbReference type="GeneID" id="71987798"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07920"/>
    <dbReference type="OMA" id="RVHCVEW"/>
    <dbReference type="OrthoDB" id="5575722at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="537"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="764" mass="85358" checksum="5FE7157D96D9A588" modified="2023-09-13" version="1">MERRPSTANSVASSTHHQHKRSASRVVDVQVNVQTIISLFVRNLRLLKFDLLQDWPAITPASLGNQDARTRIRCAEWALYQLFRVYDPATTSDKLQPFFPPLEPLQSINLRAALYRCLDGLKKGGVLGRETVLRKSMLDDCQGDKFWELCLSFSTIVLRKAVVDKTSRHKHGKPLAQRLGIAQGLSRGQKDSMLPLAIAHKAALAKVLSEKERRRQTYDTLFDVFVDKESDLHDRKADIQHRRVKQSRAAIAEEMLEQDWLASEEVRSALLNGDDAAGGDSLLTKSFAQVWAMNEKNRLFWSRSAEVGLLEGLEHRTRQQKQRLQRWQKFHDKLVQSKQPTSKGGAGAVASKLRFDQHRNMTLRDMACDPNPPSPKQHKKHDSVMKYDEILSAMREELRKTSAMEVPRSPKKKDPEITPRPRQHSYDARKPSITSLDGTSEQHHRTHSQTAVPFRPQFGRRVSSRSRSYQQPKVIRQLEPIPLKSEIFSPLKTKGIGMSPASDGRMSVFTSPVEESPGQQMGDVVGGAAAQHSRQDSTSSLALAISTSSTPSKTGSGTSTPQSARSSYGNHDSAVEMPMKASTLGPAGRNLDGMGRTVRPSLADRTRMSMALKSTEDSGDVESDAVSASTDKAEVTDEPETTALERRATLQERTRQSISLAPQPVPKVNKRSSHARSRTSTFPVNQFETPPRRSTVSISVQEEEHLPRRDITPRDKLFEEDAEYASIFKPRPKIKLSPIVSPDAVGHDHDSDVEGSPLVGRENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDR4</accession>
    <name>A0A9Q8LDR4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759902.1">
        <property type="nucleotide sequence ID" value="XM_047907414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDR4"/>
    <dbReference type="GeneID" id="71988144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08266"/>
    <dbReference type="OrthoDB" id="5412502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="34827" checksum="6F5D2FEA1A830DE9" modified="2023-09-13" version="1">MKRMPLEDDVLTCVSTDSVNERAGPDYFATILHGTGMEEGPFSVREVTIKWKDPDRGEEDRSTPAIKSRRLGPMSVIAVLSSLVSVSLLIWAALIRDGVAVIGIIAMSFTAPLLCAGSRYQLQFPRWSPGNEAAPGDVVFRTRDGAFTVVHCDVDIARLLYFAPEAPEYSMNLYTNRLSGGVVGGLMLIVSITLFGNCSWTMQAALAVTYALLNVAYWVSAILLERHSWRFDKLTITKEQVIKTDKSTAALWFAIHKSRSTNWVKAGRANPDTSAWNQWLKDAEQHTYQPAEMWDPARALRDLYRSELSMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDX3</accession>
    <name>A0A9Q8LDX3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759978.1">
        <property type="nucleotide sequence ID" value="XM_047907313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDX3"/>
    <dbReference type="GeneID" id="71988043"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08165"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="405" mass="45770" checksum="5B9AD3EC9A788EBF" modified="2023-09-13" version="1">MGWTPVKDLPHNTTDSMALLSRPIPEHDPKIVAHLTCLRDAITGKDIDRNTELSGLFHPESSEAPNVDQRLLRALTAVSPDVPCHMVLEDGLALPGDPWTKTHCECSLAFVNLYRAPVIRLTCRFKDTGSRLTLALDFHFSAIDVVKEPIANFQWTNYRDTWLQCNRQHISFTVSGATCSGFGKISRYRSRLHSSSLAMVREMQKLLRPDEPHKLCFLSDPDPASWQTTSAATLSKIRARLPGGSGPLLPSLSRYEFYNFGHGRDHIDFGEEEAESKKSLSLWAAVSHKSKLYKLPGIPLAILAVTFNEAVRTLQTGRETTKYRLPNHLDVEMRFSIPGRSEDKFSGFLLEDPWSLPHHDAFFVITSHPKEHFGQHANEPDQWDATRYNVHFTPHYKSFTTKSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDX9</accession>
    <name>A0A9Q8LDX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759976.1">
        <property type="nucleotide sequence ID" value="XM_047907311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDX9"/>
    <dbReference type="GeneID" id="71988041"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08163"/>
    <dbReference type="OMA" id="DFSHEDK"/>
    <dbReference type="OrthoDB" id="3636481at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="30531" checksum="571B82875AF1E447" modified="2023-09-13" version="1">MVSTIKDSVASASGTSDLHNIFPFFELPRELRDMVYDEGLDDHEMTLKCGMMLRAMAVANTNFLLVNRQFQEEYQQRVRKTAALTFQDRDRFHFETFNLPAGATRVIFIELNIAAIVSHNLTAFQGDPVTHNRWVAKMLQQQQNLRELSININVDFFSPGFTPEHMRDQLNSCFWTTPTQLSALHVHDIHRRKGRQHQKDHFNFSYQDKVVLKWSSATRKVELVERELYRPIAGEVTAKERAGRGGAAADRCSRSFGLISQRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LET2</accession>
    <name>A0A9Q8LET2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760275.1">
        <property type="nucleotide sequence ID" value="XM_047904052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LET2"/>
    <dbReference type="GeneID" id="71984782"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04904"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="32279" checksum="2D65F6A3A839AF39" modified="2023-09-13" version="1">MVTDDSQGNKWPDFLLSCKQVHGEATLLYYGHTLFEVPDMVSLRYWMGILRADRVLEAHMPKQIHLRLRFDNRQAKRLGPLGTGESTKVLLEEMMQKLEKDGTLKDASVIRVKTVRTQGMQDAWSPVQDLSTHGSASGASQYHLLYQFVFDGVEIVAIGLKKAPASATAILLTCKRTFTEALQLFYAATIFQANDVGDLKRWLVSVGSLRTILVKEVHFERNYLLFYVGVGDEFKKIMEEFRKELNEEEGILLREDVVKVRTRESGPRYLVAAELEDDDYLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG27</accession>
    <name>A0A9Q8LG27_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04752</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761201.1">
        <property type="nucleotide sequence ID" value="XM_047903900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG27"/>
    <dbReference type="GeneID" id="71984630"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04752"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="58"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="21962" checksum="61C522104534A392" modified="2023-09-13" version="1">MYTQTYKSPPPRRQVRHPSTHKDLPHTTANYLNTLNTLYTLYTMSNANSQGLTGTMACGLGPHVLVSPAVTPCGHHFCTACLQRYIETADICPICNAILVHRETVAFQQAPHAPATSLQNDRARVANLQQHLLPEATWGSLGVVRSTAPPTQQSSAAEDTTALDTLAEVASAAPPVDTARSASQGSPKPEERSPGNGQRKKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG47</accession>
    <name>A0A9Q8LG47_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_04415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761139.1">
        <property type="nucleotide sequence ID" value="XM_047903563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG47"/>
    <dbReference type="GeneID" id="71984293"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04415"/>
    <dbReference type="OMA" id="TQREGCH"/>
    <dbReference type="OrthoDB" id="193716at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17964">
        <property type="entry name" value="DEADc_MSS116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="114"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="336"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="603"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="655"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="694"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO16773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="709" mass="76757" checksum="137189F8D4B02366" modified="2023-09-13" version="1">MRRAFQTCSASLPRSLSTLAPASRTAQQCFRPSQLSTSTLSNLPAITRTLHLSARLQQQAAAYEDDIPSTDGAKAPITKFAELETRGVIHKNVVQALTRDMGLETMTDVQSATINEALKGTDIIAQAKTGTGKTMAFLLPILQNIISVDPDLAHRTGGRRGPRTTADDIRALIISPTRELAEQIAEEAKKLTRNTGVIVQTAVGGTQKSAGLRAIQRDGCHLLVGTPGRLKDILTDPYTRVEAPDLSALVFDEADRLLDQGFWPEIQEIMRLLPTSAEVNRQTMMFSATIPKEVVNLVRSTLKPGFQFVKCVREDEEPTHARVPQKMVAIGGFENSLPTLVEICQKGIENSRNEGARPFKAIVYYNSTAEVTLAASTLQGLQSMGHEGRDGFGSSHPWSPARVHEIHAKLTQSQRTRAAEDFKNCKSGLLISSDVTARGMDFPNVTHVIQMGLPTSREQYIHRIGRTARAGKEGEGWIVLNRIEADEARSRLRGLPLQKDTTLSIPALDLTKASDVPASAGRILSMYQKAVQRVPMSEKARVYLAQLGVFAWYPRKSELVESMNNLSQFGWGLRTPPAVPHGLATKLRIDRIEGIVIGDSEAFADRDRRGGGPPGRGPPRRALDDFGPPRGRGGGGFGGRDGGFGGRDSGFGGRGGDRGDRGGFGGREDRYGGRSGGRGDDGGRPSYGGGGNRGGDRAPRRPAYDDPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGH5</accession>
    <name>A0A9Q8LGH5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761334.1">
        <property type="nucleotide sequence ID" value="XM_047904421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGH5"/>
    <dbReference type="GeneID" id="71985151"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05273"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="153" mass="17357" checksum="F20A45CCA4A1D3EA" modified="2023-09-13" version="1">MYKAHVAEQYAKISPPRPPIDLDAIRAANPKLQPKDTFRHVKSTLAFDKEGHRAVAFPCDGIEQKQWEKEYDDGFDRSWKVEYEGVEGLSEAAVEEGGAMEVDDTVENEVIDLTQEDDSEPVAKPRAQVPQPLGRRTFRQMIKADMKERTQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGY0</accession>
    <name>A0A9Q8LGY0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 19">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">CLAFUR5_06382</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="25" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 19"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761605.1">
        <property type="nucleotide sequence ID" value="XM_047905530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGY0"/>
    <dbReference type="GeneID" id="71986260"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06382"/>
    <dbReference type="OMA" id="HPMSLDF"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000232">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 19 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19 25" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 19 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 19" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="24">
        <location>
            <begin position="136"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="465"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="20">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="UJO17239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="548" mass="62236" checksum="E2692311F108E2BB" modified="2023-09-13" version="1">MAEFGQAHRPPREYVENEGYVGSRNAMPGSAHDSLGNPLEAQEDDAENDEDYDDLFEPSDDEGLAAGNPADYTKAYNRQRKLNDNSIPEAQKPKANPQLNTRAEIDDQVKALSKHTAKLKLGQIEGGVTKHHAGAEKSDRATSEQVLDPRTRMILLQMLNRNIISELNGVLSTGKEANVYHAASTPQEETGTDAPAVTLNRAVKVYKTSILVFKDRDKYVTGEFRFRQGYNKSSNRAMVKVWAEKEFRNLRRIYQAGIPCPEPVYLKAHVLVMGFIGSSKGVPAPRLRDVEFAAEEAESRWRDVYVELLCYMRKLYQICRLVHADLSEYNLLYHKSKLYVIDVSQSVEHDHPRSLEFLRMDIKNASDFFRRKGVDILSERTVFKYILASGGSTEESGMRADLDKLFEKKAQGDEEEGDEVDDEVFRQQYIPQTLQQVYDIERDGEQIQSGSGGNLVYEQLLANGEQKDQKANGEDADSESSEDDEDSDDDEEDDAFKEKAPRGKRFEDKDVKKAHKQAVKEEKRERRKEKMPKHLKKKLISGSSRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH07</accession>
    <name>A0A9Q8LH07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761668.1">
        <property type="nucleotide sequence ID" value="XM_047905655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH07"/>
    <dbReference type="GeneID" id="71986385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06507"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11668" checksum="66817E62F38ABAB6" modified="2023-09-13" version="1">MVCLVVLGISPEQWGIEDHDLSRNATLRSLLLQDQLCLKTRVGWWIFRAAAGSVEPMRTVMDHDYATLQSQFQKGPLPETIPVTECSRGCRLVLPKGHRHIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHA7</accession>
    <name>A0A9Q8LHA7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761815.1">
        <property type="nucleotide sequence ID" value="XM_047905403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHA7"/>
    <dbReference type="GeneID" id="71986133"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06255"/>
    <dbReference type="OrthoDB" id="422206at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="78"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="497" mass="53503" checksum="B2846A1F2709EC15" modified="2023-09-13" version="1">MMADTTHATSSSGVTRAELIRTLSADSRPPTRKDESHVLVQRSDTIATRGSDGELLAHDEREHHDDRTYRVYKRRFLGLAQLVLLNIVISWDWLTFAAISSTAADFFRVSESAINWLSTAFLFAFVAGAPFTIYVLNRYGPKTSIMVASALTLIGNWIRYAGTRAGNGYFAVVMFGQVLIGLAQPFVLAAPTRYSNLWFSDTGRISATAVASLANPFGGALGQLIGPLFVGDPAQVRLVPNMVLYTAIISSIAALPAPLMSSKPPTPPSATAALEKLDLGQAFRELPRNGSFFLILVPFSIYVGLFNATSSLINQIFEPYDFSEIDAGIAGGLLIIVGLIASAVVSPTIDRTKKYLITIKILVPCIALCYILLIFMPGTRSLPGPYIICALLGATSFSLLPVALELLSIVTLPVSPEVSSVIAWTGGQILGALFIIIMDALEAYDGWNGEPRETMIKGLIFQAVIACIAVPFVLFLGTGRFRRIAFDTDGTLAAPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHN3</accession>
    <name>A0A9Q8LHN3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">High osmolarity signaling protein SHO1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_05619</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Forms homooligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761972.1">
        <property type="nucleotide sequence ID" value="XM_047904767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHN3"/>
    <dbReference type="GeneID" id="71985497"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05619"/>
    <dbReference type="OMA" id="NIVWIFY"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="269"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="214"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO17606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="35471" checksum="30F9684DBEB805CA" modified="2023-09-13" version="1">MPSFGGSDNSSPALQKMDMGNGGRYAAKRFDFGHIAGDPFWLGTIGIGISGWIIAFVSSIIADLSQEYPNYSWWSLVYMFFCIIAVLFVVGANAVFTYHVAIAAFLSAGLVFTTSSVNSLIYYPDPAKEAAAAGFILLSIVSIIWIFYFGSQPQASHRQTLDSFALHKDRAPSRNSRAMRQSYRPETTHSGGQQPQAYNTNRLAGFETVSPVAGYHGGPAGQANRDSEPRFSQPLNSQPSGNNLAAHNGASLGVGAGQGHDSSVSAPSDYPYRAKAIYSYEANPDDANEISFTKHEILEVSDVSGRWWQAKKENGETGIAPSNYLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHU9</accession>
    <name>A0A9Q8LHU9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione hydrolase</fullName>
            <ecNumber evidence="3">2.3.2.2</ecNumber>
            <ecNumber evidence="3">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="3"/>
    <dbReference type="EC" id="3.4.19.13" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761264.1">
        <property type="nucleotide sequence ID" value="XM_047903956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHU9"/>
    <dbReference type="GeneID" id="71984686"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04808"/>
    <dbReference type="OMA" id="GFMLVHL"/>
    <dbReference type="OrthoDB" id="1081007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.40:FF:000008">
        <property type="entry name" value="Gamma-glutamyltranspeptidase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040319798" description="Glutathione hydrolase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="402"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="454"/>
            <end position="455"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="574" mass="61076" checksum="DA2505BAE6E987CD" modified="2023-09-13" version="1">MRLSSYALPTVLLSQLASAAPASIAPDYDVSNPRLDPEGNKLGAVASESDICTNIGGDVLKAGGNAADSTVATVLCVGVIGMYHSGIGGGGFMLVRSSNGSYEFIDFRETAPAAAFQDMYNNNTNASLYGGLASGVPGELRGLAHLHDNYGSLPWKELVLPAVKVARDGWPVNDDLITYMDSAVSGIDNFLVNDPNWAIDFAPNGTRLELGDTITRKRYAATLEMIAEHGVDAFYEGPIAKTLINAIQATNGTMTLEDLKHYTVAIRPEQNITYRDYKVHGCGAPSSGVVGLSILKIMEGYTDIGQAATLNLSTHYVDEAMRFAYGQRSELGDPLFLEGMEEYQADMLSPETVAAVRAKISPLHTLNVSAYDPSGFESLETPGTSAVVAADVNGLAIALTTTVNTLFGSKVLVPETGIIANNEMNDFSIPGSSNAFGYIPSPANYVRPGKRPLSSITPTIVEHANGSLYYLASAAGGSRILTSVLQNVWHVLDQNMTAVEALAQPRLHDQLVPNQVSFEYTYNNETVAFMKSLGHNVTWVAPGQSTGHALRLLPNGTFEAASEPRQKNSGGIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK7</accession>
    <name>A0A9Q8LIK7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Trans-enoyl reductase iccB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762437.1">
        <property type="nucleotide sequence ID" value="XM_047905377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK7"/>
    <dbReference type="GeneID" id="71986107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06229"/>
    <dbReference type="OMA" id="QFPIRSH"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF6">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE APDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="20"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="39179" checksum="B17BE3F134D8932E" modified="2023-09-13" version="1">MAIGQPRTLPERQRAIKVLNDNSIALQEDVPLPPLNDEDVLVRVHCVALNPFDWKSLDLSPAPGSTFGCDVAGEVIAVGTSCRHSVKVGDRVFGPVKGNTSGNPENGGFAEYATIRDVVLWKIPDGMRFEHAATLGMSLMTVGLGLHYMLKVPLPLESSSSDIEGRHIFIYGAGTATGTLAVQCAALSGLRPIVACSPRHFDRMKSLGAVACFDYHVATVGDEVRDFTKGGLREALDCITDSASMNICYSALGDQGGRYVGLDQFPIRSHTRRDVYPEWIVAWTVSGEAIQWKRPYARTAKPKHKAFGQKWNPEAQKLLDSGRLQTHPIDLRSGGLAAIPDGIAMLRKGLTDGKKLVYSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIX6</accession>
    <name>A0A9Q8LIX6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein 6, OR allele</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762594.1">
        <property type="nucleotide sequence ID" value="XM_047904589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIX6"/>
    <dbReference type="GeneID" id="71985319"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05441"/>
    <dbReference type="OMA" id="MCTISSY"/>
    <dbReference type="OrthoDB" id="3647238at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF77">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="58"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="196" mass="22153" checksum="90D87DE45DB8B6A5" modified="2023-09-13" version="1">MAEASHKARSPGFNYLPLDASKKEIRLLTIRAASKSLNGQLHCSIKHVALFSNPQPKYETISYRWVDKTKGQIVVDGHGIEVPASAEEVLRRMRQRLHDRVVWIDAVCINQSDEVEKGFQVALMGDIYSTTWQNLIWLGEDDGSARDAIKALDDLLNNDDRKARASKSTSHILGDATAKKEPPDWIWPVFAIYRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJC7</accession>
    <name>A0A9Q8LJC7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">P-type cation-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762834.1">
        <property type="nucleotide sequence ID" value="XM_047906344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJC7"/>
    <dbReference type="GeneID" id="71987074"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07196"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056236">
        <property type="entry name" value="HMA_PCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01511">
        <property type="entry name" value="ATPase-IB1_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24534">
        <property type="entry name" value="HMA_PCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="758"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="784" mass="82353" checksum="9880D457B3EE1D45" modified="2023-09-13" version="1">MTCTGCVRKLGNVMSSIDGVSSHQVTFVTETAEFDLDTGVVASQDVISRIEKETGFKCSRLISGHQSLDVVMSFNLATSYEACASPGIISVEKLKKQMYRITYDPRIVGARCIIEPGMQLAPPVGDVGVSEGKKRLRKMLIATIVSAVFTIPVVILNWSNNPIPKQTVQIISLVLATVVQAIAVPEFYVGAIKSLVYSRVIEMDMLVVLSITAAYLYSIVAFGLAEAGFELEQEAFFETSSLLITLVLFGRLMAAYARVKAVTAVSTRSLQADTAQLVEKDNTVIVDARLLHFGDMVKIGPHSRIVTDGLIHSGDSAVDESIITGESAPVTKSSGDSVIAGSMNGSGTLTVKVTRLPGENSITDIANLVENALAAKPRIQDLADKVASWFIPAVVGIAIVVFAIWIGVALEIRNDDAGGAVGTAITYAIAVLAISCPCALGLAVPVVLVIAGGVSARAGVIIKASDALERSFKATDIVFDKTGTLTTGKLSVVKSETFATKLDDATTTGVLRAVLDGSQHPVAEAVAAYTDSLPISKASLEQIQSVPGSGVQALWNGSSVKAGNPFWLNLEQDEVVADLLARAMTVLCLTIDDRLIAVFGLKSTLREEAHSVVAKLQAQDLTCHVVSGDNPKSVADVAGAVGIEASCIVSRASPAKKQQYIENLQQAGKTVLFCGDGTNDAIAVAQADIGVQIGTASDLTGAAADVVLLGGLDGIISLLDTSKKAFRRIQFNFIWTAVYNLFAILLAAGAFVKFRIPPAYAGLGEIASVGPVILAAASLAWRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2N8</accession>
    <name>A0A9Q8P2N8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755228.1">
        <property type="nucleotide sequence ID" value="XM_047899623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2N8"/>
    <dbReference type="GeneID" id="71980353"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00475"/>
    <dbReference type="OMA" id="APWIMIN"/>
    <dbReference type="OrthoDB" id="5981550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="465"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO10862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="849" mass="95510" checksum="106E536169831A58" modified="2023-09-13" version="1">MESTNGNPAVGELVEIVSRYTHQLLYGCRSPDCTEVVCVSGNTNTNTTTTTRKPVRRHKPRTAIATAIGLAGQQKPQTHFCKHNASDGDKLVAEDESPRDPSSLIQLLCDTKSIQQLMTTPLDIKLLPDLEELRRRHALLRGLLQSAGQVSPLPSNAFVDNSALADGLGEASMLWLIQRLPPTRPAPWIMINRDVISKGLAYPQKNESMPSDDSYNRWTAILDILNHEPYLRLFQSTMTVVGRRTHLEEVLRRRDPKHELYPSAGRAPLAWLVASALGAVGGEDARYRLLVPFSIMVWLKRLFAQQWSSQPAFVSGGTIHGILELFRHLHHNICQGSLQNTPGCLVPDEIFEMSLLNAQVDTLSMARSYMDWDAENGNRHHVMEYPMLFSMKQLSLHFRAICHLIMKDAHSLTDAAVKLRERSGVHMEEDELSNQVRSSEQPYLLISVSRDRVLEDTWTQLWQRRKNELRRPLRVRLGEASELLEVGQDLGGVQIEFFNLVCREVSAVQTQMFITDTESGISYFRPGSLQPLYMFELFGLVVALALYNGIALPVRLPKVLYMLLSHPKDAGDSPLKTVDVRLQDLDDRWSHEVQSLQSIMHGDVGYLDYSFPFEANGLQMSVRYPDLLRKQDGKHRIQVSDMTLIDGGQPANKDCDPSRLDWPGWLVSDMGQAEDVTSGNKAQYVKQYKLHLHYGSVAPQVDAFIRGFYNSGLIPPKALKIFQPHQLKVHLEGSDHLDIDDLRAATRYDGYDAKSKYIQTFWRVVSAWPQKKQKRLLKFVTAAERIPITGASQLTFVIKRLPGSGNLETLPTSSTCFGTLTLPKYPSAEILGQKLSLALQYAGEGFGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3D5</accession>
    <name>A0A9Q8P3D5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein/NADH dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00894</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756007.1">
        <property type="nucleotide sequence ID" value="XM_047900042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3D5"/>
    <dbReference type="GeneID" id="71980772"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00894"/>
    <dbReference type="OMA" id="FWREMLP"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040049">
        <property type="entry name" value="Ribosomal_mS25/mL61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="6">
        <location>
            <begin position="41"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="21035" checksum="EE701FAE714523A9" modified="2023-09-13" version="1">MVSLPQRMRKLQTKLLAIRLGSGALVLPKEVKRIHMRFAPQINGGHMGPRKFWRHELVRLKYHNPAVPMTIDRSIFQDDPAVMSVHFGEAGSAPTLSSQPSVDERVERINMTNYTNSEILDALVRLTKAQPVEPTAEEHEELAKLEEQRRKSERNSKLSQEVRAKVKREKELLEQARGDLAAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3X4</accession>
    <name>A0A9Q8P3X4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_00589</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756635.1">
        <property type="nucleotide sequence ID" value="XM_047899737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71980467"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00589"/>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000340">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000664">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000139">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001008">
        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="96"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="812"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="1238"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="1604"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="358"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="542"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="609"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="657"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="766"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="969"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1033"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1372"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1721"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1966"/>
            <end position="2018"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="614"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="666"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="741"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="992"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1035"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1104"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1378"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1409"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1457"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1488"/>
            <end position="1504"/>
        </location>
    </feature>
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        <location>
            <begin position="1517"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1747"/>
            <end position="1756"/>
        </location>
    </feature>
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        <location>
            <begin position="1763"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1796"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1874"/>
            <end position="1884"/>
        </location>
    </feature>
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        <location>
            <begin position="1887"/>
            <end position="1896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1905"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1922"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1979"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO12269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2018" mass="219135" checksum="C68825D34087E6F3" modified="2023-09-13" version="1" fragment="single">AQLTSPHLAVRLLHSRDGQAFANAVAATLGADRRAQSEGTGSIALRGNREMAASEGGGPPASLVPPAVAALKDEAAAEGHDRGQMLRTISMDIREEREDLKKAAEQSLNAILELDLEGHVRWVSPSWEDVTGIAPSSVVGKPIAELLAENNTIFANCLDAMRKDDSKSRVVRFSIKSPPSIPYEDAHSADDKTPVEPQAGLDSLPEPGEAADAQPAEDESVELEAQGIMVYDRTTGEESHTMWMIKPAVSREITIDLPPVLADSLGIGAEMLANYLTILTDVGMNDPGNHPPPLPVLCRICERQITPWWFEKHTELCFQEHRAEMEVQMAQESLNEQRSALVKVLDALEVQARVPKQNAIDAGSPSPVPKAEYKGYTIGPTSTPSSGPTSGRSTPAAHQPRSRESSASGFGHHRARSFAVRRPLARIVELILDLCDTAMEISTPSIKDTKGYAPGELRTQSPQSEGRIQQVMQWQSPSAGSLENEHGLALLCDDTSQLAKSKIEAVFRHRRILEYSERIRIEYDILVQECIEAALQKAVRIAAGDDSDSSCSEDNGGYEPSEHNPGIMAASETANEGPEQTHGDDMFNLNTFKSAGSSSAMAMALRNTSESILQRRQSSAGSSRASSPRAGATTPKSYSAPSESFLLHKRGSIALESDTGAESDGSMRSSIASATGSHRRADSPGAELSLSRVASTRSRDRKRQSLILPSLTGAGRHHSPGRGPPPPSSPLRMAKPRLPSGTDSNPSPITSPILTQSEFNSPIIRAQHHHHHHRRQSSAALSEALGRPASPRLSAVISNPQPRAVQTSIKDFEIIKPISKGAFGSVYLSKKKSTGDYYAIKTLKKTDMIAKNQVTNVKAERAIMMWQGESDFVAKLYWTFSSKDFLYLVMEYLNGGDCASLIKVLGALPEDWTQKYIAEVVLCVQHLHSRQIVHRDLKPDNLLIDAKGHLKLTDFGLSRMGLIGRQKRAIDAKPGDAPPDLLKAGPFRRAPSVTSSRSTSFDYQGHHSPAQTPALTPAVMSHDMNQPSYFSLYREGSREPSRRTSGHRSDSGDSEALSAMFRRFSIADGRTPIEEETADEEGQESPDPYALQPVASNSSAPRTETPPQPSAMPPPVMALFDPDDSNRRFVGTPDYLAPETINGAGQDEMSDWWSLGCILFECLYGRPPFNADTPEEVFQNILMRNIHWPSEDEDDVSEEAKDLINKLMCLDPQERLGSNKDGKYDSGGDEIKAHSWFTGINWETLREDEASFVPASENPEDTEYFDSRGATMQSFAAEFEDQSSSPVQTPGADYPDRPHDALSRVRSQVNSVKRNLMPLHIPPHVRDNRSRRLSEPVAADDFGNFQFKNLPVLEKANKDVIQKLRADAMHAQTKTANSAAASSSALASPPPAPSLESSPVVPGPLKRTLSANKGSTRPQSPSLLSQANSSPNRGSQPSSPLLVSFSAGQHQDRRKTSSGSSNLSQQTSSSLQPGTSLEHAPRLPVTFKASASAPSPIKSGKSGSVHLPSHPDRASPGSRQGSVSSPRQRSQTVGSQDQDGDHVPEMLASHHHKRRSGVFDVSPSSSDNEETRHQALLRVQRRRQSSRRLSQISLADGPTFRTLDVLVCEDHPVSRLVMERLLEKLRCRTIAVTNGSEAMRYAMSEVKFDIIMMEYKLPHVNGADVARMIRDTKNANSHTPIVAVTGYLNQLQGAHHFDALIEKPPTKEKLEEVMGRLCQWRTPPEGWKPPMPQAIPPSGLRKESMPTDDSPTTTSSIAGGSFHASSSVTSNRENSIGSTTSIGEDSNHSIPFIISRQPTMDSEQGPSDLERNFGTTGGLGITRSLDQASKQAGIGHPLPHLEHQSSAPAALSGESDQPAPRRQPSNEAIQAKRRSLEKVRHESAAESGDDELEEDELGRAPVRQRSPKRHVKRSSKLGTEMMRSSSNGSVISSEDLLSAAGPRTASAEHAILEESLADVAAAATGHLTPPEFFPPAPGHHTEDIDMDARTPDDATPKPQDTGDADPDPTPRAASQEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P506</accession>
    <name>A0A9Q8P506_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757775.1">
        <property type="nucleotide sequence ID" value="XM_047902344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P506"/>
    <dbReference type="GeneID" id="71983074"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03196"/>
    <dbReference type="OrthoDB" id="5339076at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018822">
        <property type="entry name" value="UPF0646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10336">
        <property type="entry name" value="DUF2420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="800" mass="86965" checksum="EDC9A84CA896FFC7" modified="2023-09-13" version="1">MATMAFPSLSLPPLDDSMEVSSSPAGNLHDGDIDIDFDDDYYSNTGGVQLTDDEHMLEDGDPVRPPTATDEMMGDDENVIAAPVNEEVMQDSDQAGPFDLADEELIDYDDDDDVQYDGQVPLADTIFEATEPSVHDTAAVSNATGEIQSQVVEPADEEIIRQPEEEVRLQEALLEEATASGLEGTAQVDSTVQPATEVAAQPAEVQEAPANSEQAGVDVPDVHGESNQELYPLEDETKGLEAVESGTADDAEPAATIEGETASTEMHYRKPPPQLPGTLYTSTRQVSEGPPTPTDTGLHPMTVRYGHHALPLFKSRNQLDGLLKNDNLANVSLSDLIKSCRERLPVTTGETVSDDQNLILCFDTMGLFLVEDSSAASEISLQDVLDVYLLLHRNDGYDDVPPLSLTLTVQHKFTSHLEMYKQAASEGKGLSSFAIAQLPDDDHYDEEAEQEGAYEDANDTEQTLVEDVNGNEEDATAEHDHAQDFTENAAEGEHEQYDENNDYAEEGDYSGQHEGQEYIEDTNYEEYDEHAEYPDPEEEFDGSAEDSAVAPVADHSDAHTHDENVNSEAVALDSAASSANVQAAHKNDVTDTAAEDSRHELAPLTEEHDYAEDLNFDEAYAAAHHDDGGQDPATVEGTANDELGLDFGAEDPYNADLAYPEPEEADVQQHPEAGEELAQHEEHNEGHADHLENGVEGEAQPQDDDQFHTAFDLLDGEHPEDGPGDEAPTDAQDQPAATAEEVEDNIIFDDDVEEDASNDRPAEAAANNSPLGKRSFEEHADDDLFDFGEEEPDLKKARSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P519</accession>
    <name>A0A9Q8P519_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYR motif-containing protein Cup1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="449" mass="51243" checksum="7E5709CAC948050C" modified="2023-09-13" version="1">MLCWPRRGQALRNGGRWHLRCTLKASVRLYSTETAPSVSTANIRYHASGRESTSSIKPLELSINARHNLRALLRECSYLPDPAAKQYLSQHILSVFKRYDRSEWKGRVFPDVQARLQDKAREGRQALNRLRRANDGELKPLLRVLCLTYGRIGKRRHEFLGPMMPRDAVAEPAEHESEYMARDNGQDDAHAADIFADDERHLADVFQVLKTPRTGGADIALDAPDTPKALLHDRNGRMPQPTTVAGTQVYLQKLTPALHALAKSQMRISPATMTRPNPRHLKPDIAELNTAMRPMPKSRVKNMTNKWFANTLRRLLPPLPTQEWLRLQELADGKGIEEQLAQRRQRPKSPPADQPSALERVLMRGTFDVPNPTTRDVHRVTPRYMRRLYAAVFGQCPRMDWDAKNERWDVTWGSQVLARPHCSQDGQRQRALPGGLRHDVQIKIDEAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="282" mass="30340" checksum="7DAD4857BCB8935E" modified="2023-09-13" version="1">MRCIQGVIPAIFATAHLAAAQNKFITPPPGGDSGVYEGPSINVYGVGSTISLQWQVDYTRSSLSIIQTNLTRPDVPAGEDFLFRKLTDRSSYSWDVNVTGVFDLEWSNVFWFRVYNEGDGRGWTPSSYINITDNTIASPTASSTPSVTASYTARPAGSSGLTSGTKIGIGVGVGVGVGCILVAAGLAFFLLRRRKRSPPSVEVPLTSSKATDGQEQLPSYTGPTAGHNETWKSQWPEQRPVVGPNQQGQYSERAEVDASPGLHELATEHEPQEMSADRITSR</sequence>
</entry>
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            <begin position="11"/>
            <end position="20"/>
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            <dbReference type="EMBL" id="UJO15403.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <sequence length="221" mass="24146" checksum="C87E0151ED78B155" modified="2023-09-13" version="1">MATQLVLKPSPRPEEKDVPSKMKVKPATGEVTNPIISIPGQILYDIHTLYLFTRSDLKSIVLPQALFSIACAMSAAPLTQSSPMSIADVARRVPFVVGWTWIHLLVENIENQRSEHSIIEDRVNKPWRSLPSGRLTPGQARTWLLWAVCVALLTSAVLGALKPSVVLLAHIWLYNDASVRVADTLSGSATLSTPEELCVSAGEPCPYSPARKGSQRHLYGS</sequence>
</entry>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="171"/>
        </location>
    </feature>
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        <location>
            <begin position="176"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="324"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="46432" checksum="31E611039A5D1D72" modified="2023-09-13" version="1">MADTKPVIGFAGLGAMGGGMAKNLVQNGFTVYGYDVYQPLVDSFVEAGGKAAKTPKEAAAQADFFVSMVANAAQNSSLLFEGEDAVIKGLGQGKTFILCSTTPPAFLHELRERLDEEVGRSDIKLLDCPVSGGTIRAADGTLSIFESGPNEDLDNAKQVLQTMSANLYRMGGISFGTKTKTVHQLLAATNIISASEAVGLAATVGLNTQAVVDHVNTSDGASFMFENRAPHMLKNDWHPYSALAIIWKDAAIVTDTARKALIPTPVADTAEQMYIKGGQAGLTKVDDAALVQLYLPKSQPHLVSQMTSADVAMNSSHKVSKDTIVDLLAGIHLAASIEGMAFCKDLGMDRKTLYEIISKAAGWNAMFTKYIPAMLEKDSWTLADCPGAAEVGQKLADAVQKAQAIKYPTPMASSALQQFSFATLVDKSVSGQDRHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7X0</accession>
    <name>A0A9Q8P7X0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760688.1">
        <property type="nucleotide sequence ID" value="XM_047903833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7X0"/>
    <dbReference type="GeneID" id="71984563"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04685"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="11526" checksum="B87D03720A727C46" modified="2023-09-13" version="1">MSQTCPEPSAPKSILKKPPPLRNVDAMKMRDASSRMALRGGHAARKKVHFAEEEEDMDKDDGSSFEIATIGANDHNVDEALPGGRGFKQEPGPHGRDMSFWRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P800</accession>
    <name>A0A9Q8P800_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trifunctional nucleotide phosphoesterase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760793.1">
        <property type="nucleotide sequence ID" value="XM_047903494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P800"/>
    <dbReference type="GeneID" id="71984224"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04346"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="370" mass="41407" checksum="C87C18ACE0E68292" modified="2023-09-13" version="1">MVEKITASLRPKLEKPIGYTLAPLDARFTTVRMKESNMGNFVCDLMRLHYLADCCIMASGTIRGDQIYPPGVLRVKDMMNCFPFEVPCVVVQVKGKEIVKALENGVSTYPALEGRFPQVSNISFTITPAMPSGQRCSDIRIGGETIDMERKYKVATRDYMVRGKDGFTSLMLKEHGGTAESIVSDENGMLISMILRQYFMSLKVLGKWKKWSTSMGNHFGKIQDDLHEVHPVKEPNQSAQPLRVPPIEDKLHDEKLESNGNTRKSLVGTAQKHTRNTSDLPARPAKSLKVGQADADSDSDDDEDADMPAIMPSINTEHELNTVRKVMRKWRRLAGIEGHPDMATSKHEAFSCHWTKGIAPRIEGRIKFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8K1</accession>
    <name>A0A9Q8P8K1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_06132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761645.1">
        <property type="nucleotide sequence ID" value="XM_047905280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8K1"/>
    <dbReference type="GeneID" id="71986010"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06132"/>
    <dbReference type="OMA" id="YCEGNTE"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="125" mass="13861" checksum="86C57936417DD0CD" modified="2023-09-13" version="1">MPRSSTAEMTAEQESRIKIVFGAMTFGKEGAEQSRVHDSSTAHSMLDVFQKHGHTEVDTSRQYGDGASEEMLHDLRWQERGLEVSTKMCPTGAPQLGPEGWDKILHHTPEAIHYQLPVLALGCPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8X8</accession>
    <name>A0A9Q8P8X8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761737.1">
        <property type="nucleotide sequence ID" value="XM_047904944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8X8"/>
    <dbReference type="GeneID" id="71985674"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05796"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="15533" checksum="B77BF13131394E57" modified="2023-09-13" version="1">MSATKGNWQSAGTLIVTPKGNDELFDTNEMSDFFGSSFVTNTTKSDSAVEVKQALSVLTKNANGTTLPPPPPKAGSCKIVKIPKCYLTLQDARVSDNGEMVYKFLVGEDKTPDGMLAGVQLQVFKGTGQAMPGSGAGGANTFFFQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P914</accession>
    <name>A0A9Q8P914_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71986220"/>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="33"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="292" mass="33333" checksum="3C08D36CBE6A7D53" modified="2023-09-13" version="1">MPKHPRDDEEDFEIDVPPTEINPYETLGLETNASQDDIKKAYRKAALKHHPDKASPEDKESAHTKFQEIAFAFAILADERRRKRYDTTGRTEESLDLDDDDFNWVDFFREQFAGVVTSEKISDFEKKYKGSEEERQAVLKAYTQHKGKVPKLYQQIMLSDMVDDEERFRGIIDAAIEAGEVEAFSAYTDESEKSKEGRMKAARKRKQQESGEAAEFERETKSKKKGKKDSGGDMGDLAALIQQRNGARKENFLENLEAKYATKGKKGKKDAAMEEPPEEAFAANRASKRSKK</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    </dbReference>
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    </dbReference>
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            <dbReference type="EMBL" id="UJO17865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11110" checksum="E3E35BA286A6B244" modified="2023-09-13" version="1">MFQDCFEGASFWSPFYSPSENLVFDSHVYYLAAAGTYANYVNPAVCGQAAYIAAEKKFPVFIGEWSLQTMYNNTFAARETTFETQRYAWQSYAIFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P980</accession>
    <name>A0A9Q8P980_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="1" key="2">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </reference>
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    <dbReference type="GeneID" id="71986397"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="409" mass="46694" checksum="98050AB4BE0AE79C" modified="2023-09-13" version="1">MQILAVNKAIGGEAAELFKRKNTLVVVALQGLWEIETAFTTLHSLSVPILAEFGRGSVEYTRTLVRKLNWRVAITSTQRINDTENRTSHVLMLEVNLSNWKRLQYKMRSQSKSIQAFKIDARRRRSETCSLLYRVLDITLHRRDKDLALRLRSAPSTIFLLALEWRKFVALIRLKQRADHLQLNTPHDTTRNYAMIISYWVYSSRLMFESGLQAKAGRLPRSRLSLRWHLLSFDLAITRFWVAIRASQWETAQHFYKWMNHRDLHRGYNPAIGCIRHAALVLHVLIPSSVDEATLYGLLRTVEQGPTNDYVAHDVGVLRNLIQVPDPADSSSMANVVVNPKLLSVHKMPPRAFNHALNVSVVGQSGPVDRPTGLVDWTDTEHLAQLSEADKRGIKAFQAAHSLPESEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P988</accession>
    <name>A0A9Q8P988_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylxylan esterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fulvia</taxon>
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    <reference evidence="3" key="1">
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8P988"/>
    <dbReference type="GeneID" id="71986168"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF13">
        <property type="entry name" value="ACETYLXYLAN ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="15830" checksum="A608E04E551EF8C8" modified="2023-09-13" version="1">MFHIFGARETGAKPGFGLAGAFINDINNAYPSATTEAIAYPANGQANLENQTYKDSVRYGVGNATQQVAAFAKMCPDAKIVLVGYSQGSKFDARPSDQIHCGDFDDTIQLYCDADDEFCTNGTSLAIHNGYHGVYGKQALAFVKSKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K9</accession>
    <name>A0A9Q8P9K9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PAZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="1" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762634.1">
        <property type="nucleotide sequence ID" value="XM_047905003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K9"/>
    <dbReference type="GeneID" id="71985733"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05855"/>
    <dbReference type="OrthoDB" id="3636600at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="963" mass="107362" checksum="5C71A78F3B9FDB0D" modified="2023-09-13" version="1">MDTQQPQSAHDIDRIDVQTQYEVFKPTKFGVQQPFLYCDTACTGRIDQAAQVVDRSGLTKAEEAYISQCMVQYAREHFGGNGFDIWATVGGKTRFLVDPQAYPEAAEVLKEMKGLRAVLKVYETKGYPYRTRHDDLSGRSSGPDDPRPIFSNDYKRMYLPEDHRLRQTHGLRFRWSKVELWQDTAYDNNELDVEYDVLEKEINEKVGSEKITDFRLYQVEVKIHTKEVSLRDLVGLMLTANNIFQSNAARDLVNAFLTKEYISSESVVRHDNKFYDLTDKRTETLQGLKRVTGAARILGINFVGEVVMLSRSVTNSFLPMGPVSDFLQTRFGQPRSDSDDFYLENMRSTLRGRFVRTSSQTKAIAEIPGDLSHAVVPEHKHKDWPNNKANMLLFPYMPALNLGAMQRPVMMPPELCTLTPMQSIKTKQGIRPQRGAAAVELGQATTSTANTNENTEITDNVVSQSIKKPDASTLDTQFQRLYTKEMKPEFLFVEVTMAHGERAETCSWTKLQHDLAEHIRVKDCEPECKTLSLNFDPADSGLIDKWTEELSKLAKERRPDRKHFLIAAIPAGQHNKRIYQALKNICDMAVGLQSFIVGAGTLGQKLDKDIDSGKLVSKPASSKSPAGNVLHRMRLRNPAMFLPHNPDKGQVYDLAVAVHIAPISKNKDGALSSDLFLISIVARSMESATEYYTDISLVNVDDQMLMDPMRKVAFLLSHAGKPKGGRKHRITVFRSGVMPHKHAAEHGAQLALRVKPSKAPDVHTVSTATAAREFAQLESHLKEFSAEKRIQAAYILVGEDRSIIGATDPTQATAQRTDAGRTPKATTVLRTTNIHDSMREQKASLRHVSLAKDTRAPATVSIKHIGGSVASAAVEEDRSALVDPANAQNAANAFANALERLSSVFRDDHLGLYNTKWPVPTHLARLAADRAELHLARDAAGNLNPTAGLQPIAQGVCDTLYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9M5</accession>
    <name>A0A9Q8P9M5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762578.1">
        <property type="nucleotide sequence ID" value="XM_047904902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9M5"/>
    <dbReference type="GeneID" id="71985632"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05754"/>
    <dbReference type="OrthoDB" id="3650821at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="130" mass="14949" checksum="D0C69973016851AD" modified="2023-09-13" version="1">MQEEIDQWRAENQPRALSICACKVKAAFRLVKDLDPKKERLLWHPDKFSRCDEGSREAFNNMAKEIFVVVDAMRNGSRIRGTSASPRKRTMRLRATSTVHPVLKVFYGQCSPSQRPLLSYFSTMEGIPTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9M6</accession>
    <name>A0A9Q8P9M6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polyol transporter 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07724</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762816.1">
        <property type="nucleotide sequence ID" value="XM_047906872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9M6"/>
    <dbReference type="GeneID" id="71987602"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07724"/>
    <dbReference type="OMA" id="LYYIHCQ"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000100">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF4">
        <property type="entry name" value="SYMPORT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="116"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="626" mass="69597" checksum="3C8B4B1D45DE6FB7" modified="2023-09-13" version="1">MDEKSPQHGVDSDVSHEELPMKNRSAVASINLNKNLDAKVSNPLADIPYDELMRDVEVFASEKGLQEHTELLKKGALIAQDPANFENLNILDDADKEALRFEAAHKWRHPVALYFTIIVCSIGAAVQGWDQTGSNGANLSFPLEFGIGCGEDPTCPTQIRDSWLVGLVNAGPYIGSAFIGCWLSDPCNFYLGRRGTIFVSAIFCLITPIGGALTQTWEQLFITRILMGIGMGLKGASVPIFAAENSPAKIRGALVMSWQMWTAFGIFLGFCANLAVYSVGDIAWRLQIGSAFIPAVPLTLGIYFCPESPRWYMKKDRYPKAYKSLLRLRFQPLQAARDLYYIHCQLQIEKSIVGDSNYFSRFAQLFTIPRVRRATLASFVVMIAQQMCGINIIAFYSSTVFKEAGVSERTALIASFGFGLVNFVFAWPAIWTIDTFGRWALLLFTFPNMAWTLLAAGLCFLIPGEGSGRLGAIALFIYLFAAFYSPGEGPVPFTYSAEVFPLSHREVGMGWAVATCLFWAAVLSISFPAILTAMTPTGAFGFYAGLNVVALIMIFFFVPETKQRTLEELDYIFGVPTGRFMQYQTTEAFPWWFKRWVLFKKSAKLAPLYSFDETIGERESRKVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9N4</accession>
    <name>A0A9Q8P9N4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762846.1">
        <property type="nucleotide sequence ID" value="XM_047906878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9N4"/>
    <dbReference type="GeneID" id="71987608"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07730"/>
    <dbReference type="OMA" id="WSQAGPN"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="320"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="69266" checksum="7656A3BFBBF14911" modified="2023-09-13" version="1">MAKAKSAAAKSNGVSKVTRSNAQKPLEPVKALPVTLLSGFLGSGKTTLLQHILRSEHGLRIAVIVNDIGAVNVDANLIRNTHRVTKTEEKVIALQNGCICCTLRGDLLEELVRLAEIAEFDYIIVESSGISEPEQVAETFDSRLAEQISEMGNVVEGLDESTLATLQRLKEAGGLEKFARLDTTCTVIDAFTMFHDFETTDLLSSRRDDVTPEDERTVSDLMVDQIEFADVIVLNKIDRVDKEMRERVRTMIKKLNHRAKIIESSYGKIDVKEIVNTGMFNLEVAQTGYGWLQDLHAMTIREVNGRKMVTPKPETEEYNVRNFVYVRRRPFSPRRLFELLHDKFILQHPIAELDEEEGEEEEEEEEDESMEDASDSDNSDEDEEDEDEDATMTEAPELPSDATILANKRAHPLFAKLFRSKGEFWLATRPHRAGEWSQAGAMLTLAGGRPWFCTIDRSEWETGTAEIDKMVEHDIKQGGKWGDRRQELVFIGEKLDVEAIEKVLDECLLNDKEWKQWCKVMEKGSGPNSNSPEELEKKMERLAGIFDDGFPDWDDEEDHDHGAGHGHGGDAVMKDEEVDLERKDSHSPKRNGAAGAAGAAAAGGKKAKHGVRKDGTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCU4</accession>
    <name>A0A9Q8PCU4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764441.1">
        <property type="nucleotide sequence ID" value="XM_047909272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCU4"/>
    <dbReference type="GeneID" id="71990002"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10124"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="2">
        <location>
            <begin position="37"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="255" mass="28996" checksum="D13039516265866F" modified="2023-09-13" version="1">MPQSATRSNKHAKPAENSASSTENDNYDDRDGTGPIFFWREWEEPHGFLCQFCRCTFIDKPGESPIPGHENTSTHQHTFNCAEQYMMCHKALILATPDPPQKKNTSSKRSTHPPPRPIPPERKHLPEAILTSDNPNQQKYLARSVAFTPRQEKLYNRCRFEIVVQGNYYKFTQNPELKAKLLATGDRQLVEAAPNDRTWGIGFLARDARKHGHQNGWGMNLLGKTLESVRELVRSEDEEGEEARLAIANEESGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK7</accession>
    <name>A0A9Q8PDK7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764818.1">
        <property type="nucleotide sequence ID" value="XM_047909039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDK7"/>
    <dbReference type="GeneID" id="71989769"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09891"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="495" mass="55291" checksum="966962CD1B8CF967" modified="2023-09-13" version="1">MDRGHATFIHLESGPDSRAPSLKRASTSLSPAKTFHAHATHLTTVTFPRRQHAVMPPRKKGTARASDGGAGNLDDLPVGGTEEGRFSPERHGFWKDKTGHERRQNARAAADSDERGQQTALSPDLREEGDQQQDEKFKTRKSKKRKRKPEPTTTVPPTSSKKAKDKIEEHLSFVKPFDVFKTSFSAYTDADALKAELSLALKLEQSLSERPAFSSKSNHSQYLAGLKQHIAILIRQDGSLGPHYIIPLPSSTTREPAERVLDSHFLVLADKIVADADPDDQFVTRDLDFTDLNAVEYELEHSNHLRQLLKSDKKFQARASKPSIFYRTVQDWIDCLDTHKQMLKLRQNKAKHLYREAVRNGDQTSMTASQSFAGLDKVLESLTNSLRPYDDATTQKSPLTDCEDAQCNIQASSDKSNLEHMRKTFGVYLSEMDERVGDADVDVSNTNLNAPEHAAAKKDKFAHEQAVRAVSSLVAMVDAQLDNLKKRKEAEANAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEQ7</accession>
    <name>A0A9Q8PEQ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_11166</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765460.1">
        <property type="nucleotide sequence ID" value="XM_047910314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEQ7"/>
    <dbReference type="GeneID" id="71991044"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11166"/>
    <dbReference type="OMA" id="QHYLARC"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="25"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="305"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO21094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="465" mass="52174" checksum="75D8F3526BB324CB" modified="2023-09-13" version="1">MEFMTALQGGLDEQKPSLFEILSEHELNALIPPSLRYLLAVATHRNPRYLLRILNNFDELYALLSLALERYYLRTYGGGFTENFYGLKRERVLRVKGGETTRARLGAPREIRETLKLRNSDVWKNLAVMVAIPYIKRKLDEAYDVHAAGVNMLGPAYRDRERYPTDGTREQKSMWVYKWFLRSVYPSVNAAYYFSLLAWNMAYLFDGTKYHSPLLWLIGTRIRRLNDADNKAIALATQAAITSPARPGQTNSIFNPRTMSRTLLPWFQSGLKMALPMSIFALKFLEWWHNSDFARQLSKKANEGLELPPPTISGLPAPAPKPEKKVAIKDEKEGALSRRDSGIDGPPISMVTHLPILTVPAPAYTTDDSANTTSTCPICLSEVQTATAAQTGYVYCYTCIYKWVDGSHPRQEAFMEGSGEEEAVKGWVEEGGGSRSGKWESGAGRDAVTGRRVLGGTSGLRRVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEU3</accession>
    <name>A0A9Q8PEU3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765650.1">
        <property type="nucleotide sequence ID" value="XM_047910077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEU3"/>
    <dbReference type="GeneID" id="71990807"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10929"/>
    <dbReference type="OrthoDB" id="10447671at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="39122" checksum="A4F264724EBE988D" modified="2023-09-13" version="1">MASPILVQPDVAQRQPHLELLPAEVFEMVAEVADEKDLLALRLTSRQCASKILKTYTKVHFTEILFRPRDLASLMKCFRISGHPVFRHVVRTITISIDRCDRKEDNVCQVMHDSDFERKGLGLLFECLARYTKTTALRIVAREHPVATSDPRDSGDVHPYYPDWNLNMTCKRVFVDIMQILQSTPLNITSLDIATGTNWGLPMLELNDAEMDCLISLLAPLERLSLTVWRSICLIGQEYEEIDPLELILDDLPFVALEHFQLQGKRMEVWTEVEDLACSLSSHKKTLAPLHLRDIAVSDRTWIIDEDMAEQGVAAIMAKKFGCDRIMADAETDEVFWDIVVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF88</accession>
    <name>A0A9Q8PF88_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mevalonyl-coenzyme A hydratase sidH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11641</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765715.1">
        <property type="nucleotide sequence ID" value="XM_047910789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF88"/>
    <dbReference type="GeneID" id="71991519"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11641"/>
    <dbReference type="OMA" id="GFAGISQ"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF68">
        <property type="entry name" value="CARNITINYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="30914" checksum="0F590AA6B31E6FBC" modified="2023-09-13" version="1">MASQLATQPPRTPTFLLSYPKPLVLLITINRPKAMNSLGFASHWEADNLIQWFDSEPSLNVAVITGSGNAFCTGQDLIEQRDLANAREAAARGEKVDVPDQRLLRHPVSGFCGISRRDGKKPVIAAVNGWAMGGGFEICLGSDMIVASPNAIFGLPEAMRGLYAGAGGLSRLVRLAGITVASEIAMSGRFLSAAEAVQYNIANRVSKTHESVVEEAVDLAAKVASLSPDAIIVTRHGLRASWEHASVERASQDTELRYGKGLREGENLGIGLRAFAEKKQPKWVPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFD3</accession>
    <name>A0A9Q8PFD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765816.1">
        <property type="nucleotide sequence ID" value="XM_047908266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFD3"/>
    <dbReference type="GeneID" id="71988996"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09118"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="20215" checksum="5074BD0BD47B8A42" modified="2023-09-13" version="1">MSTSSESPWDVYEDDHDRDPLVIKKHNGEETLHYKKIPNPLEHFYTNQDGTTNDLDDFDLNYWIAEIEKRRAHVSSYVAEAGPTGSKYSEHDPAIDRARAVVQGQILVDTYKQLLEHFTEAAKVEVKRLKAGRQDPWERERATLWRTVVKGFQLLRDEAQQMADGMKFGAGTKPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFF6</accession>
    <name>A0A9Q8PFF6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765846.1">
        <property type="nucleotide sequence ID" value="XM_047908515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFF6"/>
    <dbReference type="GeneID" id="71989245"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09367"/>
    <dbReference type="OMA" id="YHESIRK"/>
    <dbReference type="OrthoDB" id="3634487at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48312">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48312:SF1">
        <property type="entry name" value="SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="316" mass="36029" checksum="CF8A663A6E2301D6" modified="2023-09-13" version="1">MTTQILLFDQSRSASHLLSRILSKQAKLQLLYSPLNSRGKQVQWLMSSTWAEGMSPTDLTAFNEEIEKSLKVYDEAFQKAQADNKILLLHDHPFSAAESQRVLGLIKDKVDPGNSDLFAPQLLEILLKKGTTPILTIRDPRLAVPSAFRVLGEFGLPHGSGRPNFFVSTSTLWTRWLYNSFTSHGIQPVVVDGDDIMAGGEAFTRLLAERLDLDPEAMLLSWEAPYDHVLNSGHLSKEEYEGLHPMYYKSQSVLIESSKPDAGRAARNVDLKKEEQSWEADFEEEDAKLMREAVERAMPQYQWLWERRLKRSDMQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFY9</accession>
    <name>A0A9Q8PFY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin-like arabinogalactan protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766265.1">
        <property type="nucleotide sequence ID" value="XM_047908860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFY9"/>
    <dbReference type="GeneID" id="71989590"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09712"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040393652" evidence="1">
        <location>
            <begin position="20"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="18"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="176"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="416" mass="42660" checksum="D94324E63483787B" modified="2023-09-13" version="1">MRSPLLHALLPAALVSAQADLLALLQSQPDLSTLTDLLSIADLADALAQATNITIIAPTNEAFQNVDPNIPEGVAVANRNVTSVTALLSNHVFRGLYPAASVGEVPNFVQSLLTPDFVNDQQPFTNFTGGQYIGIVKNGADVEVLSGEFAVSKVVEADIPLGENIIIHKVDTALAFGAPLQLFTARAGYTALNGALEAVDNLGLQLGLTDDGGTAIGVSDLTVFVPMNEAFQLIGSEVLSYHVISENVIFSPSISNATVPSLQGSDLQLTVTDDGAVFVNGAKVVIPNVILFNGVAHVIDGVLNPLAPPLERASLDASATTSDRVAFADATRVEALPFTSFTFAMDSQPETILAIYSTGLAVAPANAAATSTAANMDPTRATASGTAAAYTGAADVAKLARGMLAGVVGGAIAVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGA9</accession>
    <name>A0A9Q8PGA9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase virE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766267.1">
        <property type="nucleotide sequence ID" value="XM_047908661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGA9"/>
    <dbReference type="GeneID" id="71989391"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09513"/>
    <dbReference type="OMA" id="NIFTWDQ"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="527" mass="60426" checksum="D38BEA41A59F2393" modified="2023-09-13" version="1">MAYISFLLAIAALAVVGFFLLTSNSRPTPRKGSEYPPGPPGRLLVGNLPDIPAKHSWLKFKEWSDRYGPLFRFSVAGKDHYVASTEKVANDLLRERGGIYSSREQLPAAVKLLSNDLRPLFWPYNDTWRDGRKVMHQVTNATVVGNYQQTQTLESARMLRDLIKDPSRYEHWFERYSSGIIFRLAFGKTVQTGDEDIVRQIIEVVHTVERVASPGAYLVDVFPFLMNLPRAIAPFKKELEGLHQRDLRLFRKLLHDVRDEMKAGTAPQCWFRDYLERKSDFKLSEDEAAYVIGTLFEAGAGTTAAAMMSFLLAIVLHPQWLTKLQTEVDSVCGPTRLPTLDDMPHLPLVRAVIKEVLRWRPVTAGGVPHYSIRDDVYNGIFIPAGTNVHANQWAIHREAALYPDPETFKPERWLDPSYPTYREPLTTYPNMHNYSAFGFGRRICPGRNIAERSLYLQVARVAWMCDVRKKRDGEGREIVPPWYDYTAGFNVQPNWFPFEVEARSEERLRVLEGEIEVNRRSDPLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGD4</accession>
    <name>A0A9Q8PGD4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Magnesium transporter protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09337</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766359.1">
        <property type="nucleotide sequence ID" value="XM_047908485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGD4"/>
    <dbReference type="GeneID" id="71989215"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09337"/>
    <dbReference type="OMA" id="VLFGMYS"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000302">
        <property type="entry name" value="Oligosaccharyl transferase subunit (Gamma), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040400384" evidence="10">
        <location>
            <begin position="19"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO21993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="35870" checksum="E918602A2E19F010" modified="2023-09-13" version="1">MRVRQLIATALLPLTALAAKKTPAERFDAAVAKAQPINLDDKSYDALTKAPRDYSAAILLTAMDARFGCQLCNEFQPEWELLGKSWTKGDKNKESRLVFGTLDFMDGKGTFQSLQLQTAPVLLLFHPTTGPHARPNKPLERLDFNTGINKADTVHHWLSRQLPDRPHPALVRPINYVKIAVTVTAVLGAGTFLTVAAPYLLPIIQNRNLWAAISLIAVLLFTSGHMFNHIRKVPYVQADGKGGVSYFAGGFQSQFGLETQIVAAMYGVLSFATISLALKVPRMTDPRAQQIAVFVWGGVILGMYSFLLSVFRIKNGGYPFWLPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGH3</accession>
    <name>A0A9Q8PGH3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766345.1">
        <property type="nucleotide sequence ID" value="XM_047908102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGH3"/>
    <dbReference type="GeneID" id="71988832"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08954"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="326" mass="36972" checksum="6D38723D4AC2F243" modified="2023-09-13" version="1">MLSRKETSLQQEQLKAAVYRVALMTCRRNLEKAVRELVNLHAFNETYIGTEPYGPVERTPDVELGELDQDPTLRARWRKAQRDLATAENALEQHEGRNADFTAWTKEATAARNQGVAGPQVESFRDERLKKHRALYEHLQDARQTFQQVRDEAMAACFDPITVVKQRPRATKAKLRGEVFVDADIDEFLFHPMDGMTDTEGTEEEDIRDEDARRYRPRHPAWDANIVRQSGAVSSPASQASIDRRKVDVIRDRGAVWDCESVALGESRSMICQAHYGGAFQTTLRKAKIKAWREVCEAHRAAHEGHYPSIEDGTGAASADQHASFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGS5</accession>
    <name>A0A9Q8PGS5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_09353</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766522.1">
        <property type="nucleotide sequence ID" value="XM_047908501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGS5"/>
    <dbReference type="GeneID" id="71989231"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09353"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="56"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="153"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="259"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO22156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="367" mass="39419" checksum="51115C325DD10D03" modified="2023-09-13" version="1">MSAPEALNSTNPTNSESTTAITTTSPNMAESSSETNSEDQNPPPVAFYGFKSWVSQAVVASFLAGGVAGAVSRTVVSPLERLKILLQVQSTGRTEYKMSIPKALGKIWREEGFRGMMAGNGVNCIRIVPYSAVQFGSYNLYKPFFEPEPGEPLTPLRRLCCGAIAGITSVTVTYPLDIVRTRLSIQSASFEALSKAEAEKKLPGMWATLASMYKNEGGIRALYRGLLPTIAGVAPYVGLNFMVYESVRQYFTPEGASNPGSIGKLGAGAISGAVAQTITYPFDVLRRRFQINTMSGMGYQYKGIGDALTTIVKNEGPAGLYKGIVPNLLKVAPSMASSWLAFEAVRDFAVGLKPEEHLREGPKNEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGX3</accession>
    <name>A0A9Q8PGX3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766573.1">
        <property type="nucleotide sequence ID" value="XM_047908227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGX3"/>
    <dbReference type="GeneID" id="71988957"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09079"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="24429" checksum="693B1D5D5942D48E" modified="2023-09-13" version="1">MAAATASSTMRDGFRASLRQQLCNEYPYLNRDALEAMLDSLEAGLTKEAPATAASMGRSNLLTLPCELRDMIYELVFKLNGAINKIRFTCDEEDGCNARPTRVPQGSLRLLRASKPIWKSISIHIMLDLRSQLDGTFRLSYEDDDDRSRLIKMGQKQCAMIEKLVLEYAYDRPKVCREKVIFPTCQEAFQTLGLDSLGVKVEALELKEYAEDWDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH95</accession>
    <name>A0A9Q8PH95_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766985.1">
        <property type="nucleotide sequence ID" value="XM_047911518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH95"/>
    <dbReference type="GeneID" id="71992248"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12370"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="24349" checksum="D65501387D6B0E76" modified="2023-09-13" version="1">MAEHNSSGQHVPKYYDDYEEDNGTTWSNPKNVSGKSLYRAVSRHLIGTPDEGLAIQGVAMDFVIRIGAQPEHPHLAQYLARAEACLKETGIPIFTLLECPDLHPNEHVLWAIATACKVQFRVYGSITADGEAQDLLYIVGAESAYPYAVLQRPAMGTVPWRFSCLLPDESGREMLEWLIETQGLMLSERHLPDDEQTYGGAQLNKVGYAWVKKGMDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHJ1</accession>
    <name>A0A9Q8PHJ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Cytochrome P450</fullName>
                <ecNumber evidence="14">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="14">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_11806</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="14"/>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766915.1">
        <property type="nucleotide sequence ID" value="XM_047910954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHJ1"/>
    <dbReference type="GeneID" id="71991684"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11806"/>
    <dbReference type="OMA" id="DIMGPWE"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="17">
        <location>
            <begin position="495"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="668"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="461"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO22549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1050" mass="116799" checksum="81EA7CC58CFF3EA0" modified="2023-09-13" version="1">MGSTDNNGCEPIPQPPQHLYGLLGNLPDIDPAFPIKEVWRLAQLYGPIMRLNLNGDHIYVSSRELVNEVCDEKRFHKHIGQVLKEVRALLGDGLFTAFPKEPNWGRAHRMLVPAFGPIGIRKMFDGMQDIASQMVLRWDRLGPEHEIDCGDDLTRLAFDTIGLCAFSYRFNEFYTDNAHPFAQQMADVLVESGKKANRPPLLQRLYHRSEQQRQDQVQEMWKLCDKIVADRKKHPQPDNHDLLNTMLNTVDRGTGEGLSDENIRFQLATFLVAGHETTSATLSFTYLNMLQNPATLLKAQRQVDEVVGDDVLTVEHLSKLDYIDACIKETLRLSSPIGAFTVGSDEDQVLAGKYFVPKNTEITILNKLLHRDPAVWDDPDSFKPERWLNGGLQKLPPNSFKPFGSGMRACIGRGFAEQEMIINFAMVLQRFQLELADPSYELQLKSTLTIKPWQFRMKVRRRQGKSPHVGIPGGLQKATEKEHRTHQAAHRPAKDDGGEEAFGGTCEALAQSLQTACSDHGFEATIAGLDAATEHAPTDQPVIVITSSSEGQPPDNARKFVHWLGELDPQKQALKHVKYAVFGVGNSDWASTYHKIPRLVDDLAAKNGAQQIISAGFSNVKEDPIGPWEDWSDKLLEVLSGDKSVTKEKTTLQANIEPDPLSRTLGGMEMNYGTIITNRELAGTEVGPAKRHLEIQLPHDADYQAGDYLVVQPHNPPESIHRVLAHFDLNDTDLVTFTNSPKKYLPSTPTPVGTFLAEAVELATPITKRQLESLAPYATTSEQKSALQNYITTYNTTTLTNRYSPLDILTTLSLTTVPFPHYIDLLPPLSPRQYSISSSPLVQPESVSLTIDVHSSPALSGTGLFQGVASTYLATRRIGDRISCFIRPTNVGFRIPSVDVPLIMICAGTGIAPMRAFLQERSAIAAAGIKTLAPALLYFGCRHRDHDNLYTSDLSTYETAGIVKIRTAFSKVGPNAPSYVPDLVWEDREEIADLFTAGGKIFLCGSAARLGRSTDDVCKKIWVERTGKTSEEAEEWLRGVRMERYVSDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIJ2</accession>
    <name>A0A9Q8PIJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_12500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767496.1">
        <property type="nucleotide sequence ID" value="XM_047911648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIJ2"/>
    <dbReference type="GeneID" id="71992378"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12500"/>
    <dbReference type="OMA" id="LMACHCT"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="152" mass="16813" checksum="C60017F0DE16E54E" modified="2023-09-13" version="1">MAAAIKALNAKIRSNPVSDYFCSTHFWGPASNFGIPIAAVMDTQKDPEIISGRMTAALCGYSGVFMRYSMAVTPKNYLLFGCHLVNFTAQSTQAYRFVNWWYMGGRETAFEQRAKEGLGKVEETAEGVVGQAQELAEQAARKAKEVKEQVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIQ5</accession>
    <name>A0A9Q8PIQ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Conidiophore development regulator abaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767518.1">
        <property type="nucleotide sequence ID" value="XM_047910929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIQ5"/>
    <dbReference type="GeneID" id="71991659"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11781"/>
    <dbReference type="OMA" id="VDAHITC"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
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        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00065">
        <property type="entry name" value="TEADOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00554">
        <property type="entry name" value="TEA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="8">
        <location>
            <begin position="128"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="6">
        <location>
            <begin position="128"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="531"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="557"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="673"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="780" mass="86795" checksum="23759EDCBB5EF08F" modified="2023-09-13" version="1">MIQPARVLPSNAPPLADTENSHSSRVLQEHSGNRQHHDYSYGNPSEQKYPASLLTENVYTGQQISQPLHHYRQTPLQRHHYRHGHGRHYMGGDDITRIKKAAAILYHRFRNSEQYMKYRGRQHKDDKGNQGEQKWPDRLELAFFEALVRWPPMGRRKMMHKDKQRGRNELIADYIEEVTGEARTRKQVSSHIQVLKPFVEGDPFIMRMLSKEDLCGPGGQLYRGGGRAASYHHDTRRTSTYPGMIPHAPSAAATVPIDAHMIQKAKSLLEVFEPLEFQMFVQQKFKDDSVNRLHTYTQSISDPKQPDDEHLPDWHSLQRSPLLASIHAVRPLDCNVLLAEASLAFPTRSFKGEDGKSLPGVELGISFLCNSRHLPVDAHITCSTNFYHNMRHLKDHSGRAQVQLTESSDRTSVETQLKFGSNFWAKTLATLAGSVNAPATSSRDPRQEVRDHIAGITAAQEVAVRTETGHERLLVIHWKFRLSNAERGRAYWRRLILPQSSSSSTSSEEEQHYGDPRPKTNRNDSVYDYSLTYTDPTPYASASTSQPALQSPFEYDSTSGSGSALTSATWPSMDETNTAPHSAIDGNFPDHAFDFDGGNINLSYDPTLDFGNFDSTAFDVTVSDSIPGTTGAEFGTDPALGEYSQTSTVQEYGQGSQEYSQPEFSQPAAADYSHTQPQPHTQPGYTQDFTQPWTDSYTTTFDSQLSAGASSYPNDAHDSGVFEGYHAGYDPTYQPTLGPPEGQAYGGAGQDAVVKEEGDGGDSLNALADVAGSRFLGHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ27</accession>
    <name>A0A9Q8PJ27_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-binding monooxygenase acrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767696.1">
        <property type="nucleotide sequence ID" value="XM_047912189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ27"/>
    <dbReference type="GeneID" id="71992919"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13041"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO23330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="578" mass="64884" checksum="30615A48ADD2DA65" modified="2023-09-13" version="1">MTEQKTVPYLNGEVPVVGGAEVNGNKAEVHEFTAAQPATTNGISNIETDALVIGAGFSGITAIDRLRKAGLRVKCFEAGEDFGGVWYWNRYPGARVDSEAPFYQLNIPEVYKTWNFSERFPDHQELRKYMAHIDKTLGLRKDAYFNARANDVSWDEGAGRWTLKTEQGHVATGKYLLLCTGLLHRTYTPDFPSIKDYKGEIYHSGAWPENWSAKGKKVGLIGAGATAVQITQELGKQADELTVFLRRPSYCLAMKQRELTPDEQRHLKSFYPALFKAGRNSLAGFPNARESVGAAEVSAEVREKHFKESWEAGGFNFTLSNYNDVVISPESNKLVYDYWRKRVCERLTDPEKQKIMAPEKPPYYFNTKRSPLEQDYYEVLDQSNVHLHDLSKSPLRSFTEKGLLMADDKAYDFDAVVLATGFDSFTGSLTHLGLRNKDGILLKDLWQEGVNTYLGLTIAGFPNMFMAYSPQAPTALSNGPTIIEAQVETIVDMIKKLESEGTKVIEPTKEAESQWKEHCNSMLQYTLFPFTESWWNGSNIPGKKAENMSYIAGINAYEAECRATMEGWKGFNVVAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJA7</accession>
    <name>A0A9Q8PJA7_PASFU</name>
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        <submittedName>
            <fullName evidence="2">C2H2-type zinc-finger transcription factor orf8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJA7"/>
    <dbReference type="GeneID" id="71992471"/>
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    <dbReference type="OrthoDB" id="5366256at2759"/>
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        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="47950" checksum="B4FDED4F002458D0" modified="2023-09-13" version="1">MTSVITMDSPSFQSLAHQPRVRAHSTFAAQSSINKHGAISKRSHLDGRDRSISASQADRLFHFAAEQSTTQADIDQGTINPSSTLGIQWLTPQHSPEPQGSETEHPIQPYPQWTAPTPPRSDSGVPSVSVDFNDLPVATGISISPEFAFEQPTAQAEMSSLGFLLPTQYGSGPGESDPASYTMDQNYIPPMRMSQPATTSGTTAYAQTVSSSPSHYQQSSRTPDLSSSRRHSEMPASSAGQAYDQSYRRISSPYDNMSSGAYSMPQTQNIPSISGITQSPLPSPGMSHTSGTPSMPQYNSSMSRSPNMYDSTIYSHQPAYTTAPTATQLYASSQQQQPIPYPPPPPPPPYSASNAALAKPPSSSDSSIRVLNQRPKPQCWEHGCNGRQFSTFSNLLRHQREKSGTSAKSYCPKCGAEFTRTTARNGHLAHDKCTKQRQVGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJC6</accession>
    <name>A0A9Q8PJC6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13014</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767931.1">
        <property type="nucleotide sequence ID" value="XM_047912162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJC6"/>
    <dbReference type="GeneID" id="71992892"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13014"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000075">
        <property type="entry name" value="Sporulation-specific chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040138656" description="chitinase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="50"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO23565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="445" mass="49721" checksum="867C57238BCE32DD" modified="2023-09-13" version="1">MMYKPLLSVLLFLSAFGAASQPRHAHLHNKVGARSLELARDGGKAVHQGFKTVGYYVNWAIYGRNWPPANIQATDLTHLLYAFAGINNKTGAIYLADEFADIQKAYPGDDTNATGTNMYGNLKQIYNLKKTHRNMKTILSIGGWNIRTYFAPALADATGRATFAKTSVRMLADLGFDGLDIDWEYPNSTKEAADLVDTCRLFREELDAYSLNATGGQYHFLLTLAVPAGPDHFKFFDVPGLAPYVDFINLMGYDFQGSFSNYSGHNANMYKSQTNPRSTDFDAQTAIDYYINSGWPREKFNLGMPLYGRSFANTSGPGTNFTAATDGSWENGAWDYKVLPLNGSLVSPVYHDDKIVASWCYNNATRYMVSYDDPAIAKTKAQYINAHKLGGAMWWETSGDRPLNDSRSLIRTVKEEFDQCGGLEQCENWLQFPQSKYENLRAGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJC9</accession>
    <name>A0A9Q8PJC9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767982.1">
        <property type="nucleotide sequence ID" value="XM_047911664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJC9"/>
    <dbReference type="GeneID" id="71992394"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12516"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="187" mass="20814" checksum="4AF4D007A3903792" modified="2023-09-13" version="1">MESDTVPSPQISDTGLEIRLAGRQYRNARMSVQGTISLLTRDRPLEKIFAHERSAHPLAPNWVTLTLILALDADGIAVSNELDLSHYVDTRLSKNDAYIECPSTCTKLEVRLRLPTAHPPYKDPCPTLRQQPVHLQQIKIRHLAFSSDVYHDSTAGGSRDEFGRVVSEYAGTVFKLRTPDGTAGIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJJ0</accession>
    <name>A0A9Q8PJJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Atrochrysone carboxyl ACP thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12535</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3R)-atrochrysone 2-carbonyl-[ACP] + H2O = (3R)-atrochrysone 2-carboxylate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:64236"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:20479"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:234107"/>
            <dbReference type="ChEBI" id="CHEBI:234110"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:64237"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767951.1">
        <property type="nucleotide sequence ID" value="XM_047911683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJJ0"/>
    <dbReference type="GeneID" id="71992413"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12535"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="82"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="336" mass="37226" checksum="D38365A9A970D70E" modified="2023-09-13" version="1">MFSRIGLTQRSSISRPPLTSNAARSRSCIGAQHLRTPAISGFGVRFYAVKMDQLPKLPEVERLSPRVIRILGHNPSKFTLQGTNTYLIGTGPKRLLLDTGEGKDAWLASLKSTLQDEKASISDVILTHWHPDHVGGVAQVLGLGSDADVKVWKNQLHPMRKGEWTNYDDGHVFDTEGARMRAFHSPGHTLDHMAFILEEEGAMFTGDNVLGHGTAVFEDLAVYIDSLERMKEEFAGRAYSAHGAVIEDGKAKIMEYIAHRKQREVEVLEVLRGTPPGGEEGWMSGEVVEVVYKNYPEHLWAPAEGGVKQVLRKLEGERKVKQVDGGRWTLGEKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK03</accession>
    <name>A0A9Q8PK03_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tetratricopeptide repeat and J domain-containing co-chaperone DNJ1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12939</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768191.1">
        <property type="nucleotide sequence ID" value="XM_047912087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK03"/>
    <dbReference type="GeneID" id="71992817"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12939"/>
    <dbReference type="OMA" id="PFAHFQH"/>
    <dbReference type="OrthoDB" id="1726119at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000224">
        <property type="entry name" value="DnaJ and TPR domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040373433" description="Tetratricopeptide repeat and J domain-containing co-chaperone DNJ1" evidence="9">
        <location>
            <begin position="24"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="405"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="468"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="58427" checksum="C4F743EEB2F58ACA" modified="2023-09-13" version="1">MKLGLSSLAIGALCLSSVPGAFALPPADIDKDTPVSQLIATANANLAQGKAQEALTYFDAAISKDPSNYLTLFKRGATYLSLGKNQQASRDFDQVLTLKPGFEGALTQRAKIRSRNADWKAAKADYLAAGKKDTQDWLDLEEAEGAEKLSADAEKAGDWEACVTNAGTAIMVAGTALELRQRRAKCRLEKGEIVEALADYNHALQINSNLKEPYLQIAAMTFYSLGETDKGIKTVSKCLHNDPDNKACSRLRKSQKAIDRTLKKFKTLHEKRQYNSAVKLLIPQGEEPGLLQDVKDDIKVHREAGYIHVKAPDGLYGNLVESACECYTEMNNLKKAAPFCDEALTYNPNSLPALLSKAQRQLDADDFEPAIGTLNAAKEEHGNIQKIQDLLNKAHTLLKRSKTKDYYKVLGVDRDADERHIKRAWRKLTIQYHPDKAAKNGVTPEEAQKKMSAINEAYEVLSDPELKARFDRGDDPNDPQSGQQPFQGSPFGHGPGGQPIFMRQGGGGGGAHFKFQGGQFPFQGGFPQGFPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKJ9</accession>
    <name>A0A9Q8PKJ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heat shock protein hsp9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768445.1">
        <property type="nucleotide sequence ID" value="XM_047912212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKJ9"/>
    <dbReference type="GeneID" id="71992942"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13064"/>
    <dbReference type="OMA" id="RSHDNHA"/>
    <dbReference type="OrthoDB" id="2348401at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2440">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007250">
        <property type="entry name" value="HSP9_HSP12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04119">
        <property type="entry name" value="HSP9_HSP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002590">
        <property type="entry name" value="HSP9/HSP12_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="84" mass="8725" checksum="4B84319594611187" modified="2023-09-13" version="1">MTDAGRKDLSSKIGDKAQPDSSKSTLDKVGEGLSGAGDKAARDLVPDSQKSTTQSLGDKASRSKDDAKDESILDKAKNAVGMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLA8</accession>
    <name>A0A9Q8PLA8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13712</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768850.1">
        <property type="nucleotide sequence ID" value="XM_047912860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLA8"/>
    <dbReference type="GeneID" id="71993590"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13712"/>
    <dbReference type="OMA" id="WNAELEN"/>
    <dbReference type="OrthoDB" id="4037694at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO24484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17179" checksum="970B02B5851E1EE9" modified="2023-09-13" version="1">MGFTTGLLGGFTLTASLLYLSTELHSRNRIHQAALLRQQALLLNNIVEPQPDLPPPTARAVKAGLWETAKDKWNAELENNVRKVQRTDWAAVGQNLEESVSGLWRRAFQSSREGAEVAGEKISEQVGLAEENARQGLKMAAQGVEQKVKKNASYGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ34</accession>
    <name>A0A9Q8UQ34_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762990.1">
        <property type="nucleotide sequence ID" value="XM_047906665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQ34"/>
    <dbReference type="GeneID" id="71987395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07517"/>
    <dbReference type="OrthoDB" id="3943664at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040470505" evidence="1">
        <location>
            <begin position="18"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="22275" checksum="7AE610292E13CF2B" modified="2023-09-13" version="1">MYSLILLLLSALELTAAISSHRSVCERDPYRKIVPLSKYAPALEYCSKKFPSKTVTVTVTVTKNGYKHVAIAEPGQQPAYGGPEKAFWSLKNNGCAFAQTGSSPTGPCPNGAAFANTIRASFREFGICTSAELVDPPVTREERNGIRFRDSAQQGCAETCDTSRCAAVQYDPTDNQDPITCLWFGEGSTGYTLAANPTAGVAIPLVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR90</accession>
    <name>A0A9Q8UR90_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein BRX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07175</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763874.1">
        <property type="nucleotide sequence ID" value="XM_047906323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR90"/>
    <dbReference type="GeneID" id="71987053"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07175"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000009">
        <property type="entry name" value="Ribosome biogenesis protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="52"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="338" mass="38136" checksum="6F441665E8FBEEDD" modified="2023-09-13" version="1">MSSRPSIPTGVVRLHIRRRIAPAMASVYKQVAKQPNGKSKDSGDDVKPKNKQRVLILSSRGVTYRHRHLLSDLNSLLPHSRKDAKLDTKTQLHQLNELADLYNCNNVMFFEARKGKDLYIWLSKPPNGPTVKMHCQNVHTMEELNFTGNCLKGSRPILSFDAAFEKQAHTRVIKELLTHTFGVPQTSRKIKPFVDHVVGFTLADGKIWIRCYQITETEASKKKEGDSETPSDASAPQSTVEKSAKGETHVSLVEIGPRFVMTPIVILEGSFGGPVIYENKEFVSPNQIRSDLRRSKAGRYNRRAEATIERKAKKRDMGLRTGEGTREIDELDDRMVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URB9</accession>
    <name>A0A9Q8URB9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="14">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_10655</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764010.1">
        <property type="nucleotide sequence ID" value="XM_047909803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URB9"/>
    <dbReference type="GeneID" id="71990533"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10655"/>
    <dbReference type="OMA" id="PESFGWD"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000047">
        <property type="entry name" value="Mannosyl-oligosaccharide alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040164080" description="alpha-1,2-Mannosidase" evidence="16">
        <location>
            <begin position="16"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO19644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="525" mass="58040" checksum="720B7512B1446508" modified="2023-09-13" version="1">MRSLSIIAAATAVAAFPQQYQQPPTHGGGNDGKPSYVGTGESAQERQERSAAVKEMFEFAWNGYYRYAFPNDELQPVNNSFSNSRNGWGASAADALSTALVMESGEIVNQIVNYVPSIDWSVSKDDEAVSLFETTIRYLGGLLSGYDLLTGPLKELVDDESKVQALLDQAQNLANNLSYAFDTPTGIPHNNLIFSNRSNTGDTTNGLATIGTLVLEWTRLSDLTGDETYGQLAQRGESYLLNPQPLPFAEPFPGMVGTNVAIDNGSFVDNSGGWNGGDDSFYEYLIKMFVYDTSRFAEYRDRWILAADSSIQYLASHPSSRPDLTFLAAYKGTTTINSSQHLACFDGGNYLLGGIVLKEQKYTDFGLQLVDSCEDTYSQTLTGIGPESFSWNTTTLPANQTEFYERAGFWITNGNYILRPEVIESFYYAYRVTGDRKYQDYAWSAIQAINATTRVGSGFSSINDVNEAGGGGFMNFQESFWFAEVLKYSYLIHAEDAEWQVNYEGKNEFVYNTEAHPMKVAGTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URC0</accession>
    <name>A0A9Q8URC0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763936.1">
        <property type="nucleotide sequence ID" value="XM_047909059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URC0"/>
    <dbReference type="GeneID" id="71989789"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09911"/>
    <dbReference type="OrthoDB" id="10608673at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="218" mass="24682" checksum="491E12C30647DCDF" modified="2023-09-13" version="1">MNALKISDFDSRDNYELLRKTAAGKDGAQIVEAYRTLPEKAARYKLAKNVPVTLGTPRERQNKRIIVAVLNLAETYPGRTPASSEHNQLVWKCRVALALVFTILRDLQEHAGDVSKSYFHGKLKGEVVQPWPPRYAQDGQPEAEPANTQGTKRKAEDEPPRVVESQEKRRAFSDTPTGRALQEVWDNAYLGEDHWEDHGIRDSAKDVVHKTPYEKPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URR9</accession>
    <name>A0A9Q8URR9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10595</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764372.1">
        <property type="nucleotide sequence ID" value="XM_047909743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URR9"/>
    <dbReference type="GeneID" id="71990473"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10595"/>
    <dbReference type="OMA" id="WVIIVAR"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="18"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="532" mass="56756" checksum="8111E0BF78083A0B" modified="2023-09-13" version="1">MERALAAYKAFRSSKALITFTVAYAVFTDQFLFAAIIPVAPFSLHTQIGIPEDKVQFWTAILLAVFGIAAFVTSVPWGWYTDRSTSRRMPFTIGLLILLGATFMLWFGNHIVAQVIGRLLQGFSSTVVWTTGLAVLVDTVGHGQIGEYMGYVGIALNVGSLIAPLLGGVMYQSAGFNAVFGMIVGVVVLDILLRFVMKEKSLVAEEDLVTESSDEVDLEAGKAERKTSVITVRPVRTDTMESIVDPGTASPRRLSGRTMSFPSRRPSDAPASPLAAVIQSWRATGITTSDCPLQAVEEKSSGDSTSRGDSLFSGDIIPSPEGSNGDLRASLHRYSLQPRPQHPPSKVPRILRLLCSTRMTVTLWSVLVLAGTFSGFQATLPLFVSSTFHWNATGGGLVFLPLSAPALVGPAVGKLQDRFAGSGRWFAFAGFAVLSVALILLRLVEHNNTGQKALLIVLLTLIGSCMPLALEPLFGETIYGADQIDLADREAGIVREGGAGSYGQANALFNMAWAGGCALGPVLAGTMIDHVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URY9</accession>
    <name>A0A9Q8URY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764594.1">
        <property type="nucleotide sequence ID" value="XM_047909553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URY9"/>
    <dbReference type="GeneID" id="71990283"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10405"/>
    <dbReference type="OrthoDB" id="5398515at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="536" mass="59323" checksum="398B5062BFBB1194" modified="2023-09-13" version="1">MNELCEQLHKMEPPTTPPRRTPRLNRARTPPSPRHGALFDDYEPYSPRRSTRSTLTSNPYSSVNKTAGGDSLAGIHETPAKKPRFAIENLLSPPSSPASAPRNKLNFNATPRRADNTTHDNTNKKHHLDPSSSSRGISGMLPTPSKTPTMTPARKHQRASSMQDTARVLRFQPDDPNDVMPTRKDKRKQKPARNVAAQDFGLDGDDFSETASQRSGSFQIYAEAHARVPQLDTSAENVFYRPRANTIPATRSSPCRTRKTQAQILEDQRMEEAVEREEGMVFMFRGKKVFRKFQDSETGDVNLEHSDRQRALKRSVGTAAERPITRSNIQPRLLFGTFDSGYAGTDDVDEEAETDLDVSDAPVIEEVQPVSVPIKVASTPARSKPGPQRIMTPPTTARTTRKRDAEEALDNQATPEPTPARTNKKKKVAIDAVPIFRDCTPEPVLASEPEAAAVPLTPQRSTRKKPAERNLTPIIEDELDAAPVSSQESSTSATRRKPRSPFDDWPRTKSAHKREADPLESSGSKRTRGAAIAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US23</accession>
    <name>A0A9Q8US23_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="8">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="8"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764701.1">
        <property type="nucleotide sequence ID" value="XM_047909400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US23"/>
    <dbReference type="GeneID" id="71990130"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10252"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000012">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="39033" checksum="5C2CF3F2023946B0" modified="2023-09-13" version="1">MSAINLEEVHDFLIQIAHDAGKMISTAKPVAAGSGQKKNSADLVTETDQAVEKMVGTKLRERFPEFAFMGEETYKDADKLTDKPTFIVDPVDGTNNFFHGHPYVCVSLGLAIERKPVVGVIYNPYTKELYTGIKGKGSFLTDAQHDHVRLPLKDPEPLKDLSHCLVAVEWGSDRDGDDYETKVNTFRNLCASKESGGAMVHGIRSLGSAELNLCGVAAGHLDVYWENGCWAWDVCAGWVILEEAGGRMVGSQKGDWNPSVDQRRYMAVRGGEDQTKIIGEFWSHVDGLLNKVKDKVTSGGSGGGSGGGAGGAGEKYINDATHKVTDQATDRAGLGDKYDDKINKFTDSQTNKQIFGGKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USE0</accession>
    <name>A0A9Q8USE0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_11145</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765105.1">
        <property type="nucleotide sequence ID" value="XM_047910293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USE0"/>
    <dbReference type="GeneID" id="71991023"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11145"/>
    <dbReference type="OMA" id="QYYELYR"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="12937" checksum="7BCD75C8E1A8E2D4" modified="2023-09-13" version="1">MAQPAGQQSFYELYRGSSIGLALADTLDDLISSRRIEPQLAMKIMQHFDQHIAGVLGEKVKARMSFKGHLDVYRFCDEVWTFVIKDVKFKMDNALQLEAERVKIVACQSKDKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USK3</accession>
    <name>A0A9Q8USK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10886</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765285.1">
        <property type="nucleotide sequence ID" value="XM_047910034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USK3"/>
    <dbReference type="GeneID" id="71990764"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10886"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="599"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="476"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="635"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00056825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="645" mass="70625" checksum="45D7AFCDD9C1EE6C" modified="2023-09-13" version="1">MSTAIKSIKALAPLLDRVLIQRAKAEAKTAGGLFLPETAVKELNEAKVLAVGPGAMDKDGKRIPMGVQAGDRVLIPQFGGSPIKVGEEEYSIFRDHEHLTEDKAPQRSIFAHTEGIQNGGPFCRASAFLLQLFVTTHAAIGYRQNTILSFALLCGHAFAAPAVESASATRLAAFGREDVPAATHISVTAAPSEPTALGVSQLEVAASSPFWPWSNNTDIKAPVLVHGPNGTVAVHLNSTSRVAHQDINSTNHDSPAPLSAEKEKLLKKYYNIYSKYHLAVATRERFTRYLAYTKAAIKDEEAHLHYALEVWDNNLWSMQKFCDGKQVCILPYQTRINEMRVTAQDTEKGLEKLDHYQKQLEKKVAKAEKQVERASEKLTPLYAEFYKQNWNVTVPVHHGPTITILTLTPTPTPTLHSAAGYAAPTTESAAGYAATSTESAAGYTAPTYHPIAKREDIDGPIDGDDDFHIDSDLMTLKNLEGRLRAIEAYLAQLERQEEQSAKEIDYLGAAYTHTANKLPDLYINRLDLAKELLENLDGDTHDLEEESDRTGEALEQAWGTIDDLWKSIGETMPETMKTKMNISKHEAIKTEVEAAIEEAQDKTDATATATTAAPSDDATPTAPAHLCNAPNDCPEPYRPDALHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTM2</accession>
    <name>A0A9Q8UTM2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766440.1">
        <property type="nucleotide sequence ID" value="XM_047908078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTM2"/>
    <dbReference type="GeneID" id="71988808"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08930"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF2">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="740" mass="85503" checksum="EDDC0DBA399129EE" modified="2023-09-13" version="1">MADDFYKNPEAMLRALGMGGPGGFPMPDIATPDSVRKQRNERVANIFKDYRLLQNILEGYESTIQKRWLKKTKEQKRRILLAAWEDLTKPKTLLLFLNARGRNPPSDFAAADFEAMHIGVINHAISPVFLNEYVILFNGKTEESEYGQLLSWDDHPDAFQWLHTRKHMQPGEGLLILESQEKTIDFLVKCAKEILHDVSMDNLLESPFQPAPPSISEQETGLASLALMKAEAAYRLPARLDWNRIQSLLAAKRDAVEDHLWSLREDPSYFSYTMRDAREHRQEMLKDARDQTHPVFRFNKEEILWARVIGDEVTIAHILLEQWTELHRRSVELGELEKKYASEIKAEDDLPEEYLFAILGFRHVLTQFTHGPIGQLKVSFLASPPWRKYFVHQPHDDPKQTSNVLVSKPGVHLQDPERIILWLVRTLWQDERTVFLLRMTNIVDQLQHIIDSDPQPKDLISSYVAAQIANMFEDQLVDLQDDIDADFDKRRQPWVRLFNATKGSETLLARYGAPTDGRFEYPVQKRRTKENTDTATRRLMLQPRLLQRTPEWVEPESKQGKKGAPANDTIEALCKPLSEIYFDLERRTESTTKKDPAAHQSKTKQKTRGVGAPEPSTANDATAQSNLISLDQQPTFEVDARALKVFRTIFYTPSSNSNPGEVPWMDFVHALVSTGFKHEKLYGSIWQFSPTRLDVERSIQFHEPHPSPKIPYWVARRHGRRLNRAYGWDGEMFRLAEKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU97</accession>
    <name>A0A9Q8UU97_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767072.1">
        <property type="nucleotide sequence ID" value="XM_047911608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU97"/>
    <dbReference type="GeneID" id="71992338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12460"/>
    <dbReference type="OMA" id="WCYYALL"/>
    <dbReference type="OrthoDB" id="5337308at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040294089" evidence="2">
        <location>
            <begin position="25"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="523" mass="56157" checksum="F0B0AF0605DEE126" modified="2023-09-13" version="1">MASGLLSWLVPALLLGAAVAPGNASPIAGAVVGNGTADGLLDIDGFGDGSLAKRAMPGAASDEVVRKYEQLGHTQVSEWLFATSADATANLIGPVVKEVFNLNGDPLKHNWQRHLVTRKEEVLIKDWGINDISGTAVSAASDPVNMLDKLTVGRQPTSPAQQLEKWQEERKAQSGLYPRGPNVRYQVHQQTAIPAYYGHQQPFVMGAGYDVTLNIVDGIIIVDEARGPTRRDDGFRIPFNRFPDITSWSEVVFDLWLRIKPVKRPRQSVMTVAPNHGKLNPFSTFEPGLKVKEFLGVEGFLNYVFMVNIREPTEEVSIIKRCLASRTDANQYPGYDDAQRFSVGHWCYYALLASEHGEAIAWLLTTHKGAGTVKIARMGNKVLKSVTVFATDPCPADGQQSHPTLMWEIVDQDPKWIESAGPSPFGAQSAGYQANTGTTSSTSGQNLQVPGQESPGYTGKGKNPAQQGQSPGGESDDLAWAINYPSSSDSHGPTPDPPNVPKPGDGAPGVPGSAAGSSSHQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUX0</accession>
    <name>A0A9Q8UUX0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">V-type ATPase assembly factor PKR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767775.1">
        <property type="nucleotide sequence ID" value="XM_047911808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUX0"/>
    <dbReference type="GeneID" id="71992538"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12660"/>
    <dbReference type="OMA" id="INWFAME"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="173" mass="18997" checksum="D0AA23C4E228C896" modified="2023-09-13" version="1">MADFLANLWESVFTAGPTPTLLVATNVTFGALQILLAGLLFATYSIHFAILSVLSGGLWWSTNWFATELQQAQAKEAEAERLRRRQKQDEADDEGEDTEVEDAGRMKESFTFEPTKGDEKIRKEILDAMGAAPATGSQAVPGGVQTRQRKVEEGNVSASEISTDSEWEKVEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV21</accession>
    <name>A0A9Q8UV21_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12716</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767879.1">
        <property type="nucleotide sequence ID" value="XM_047911864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV21"/>
    <dbReference type="GeneID" id="71992594"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12716"/>
    <dbReference type="OMA" id="SYPESKY"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000095">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="7"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="402" mass="45206" checksum="230710EBF3E5A83B" modified="2023-09-13" version="1">MSYQPGFRSVAYFVNWAIYGRSHQPQDIPAEKLTHVLYAFANIRPESGEVYLTDPWSDTDKHYPSDSWNDTGNNVYGCIKQLFLLKKRNRNLKILLSIGGWTYSSNFAAPASTEQGRRTFATSAVRLLKDLGLDGLDIDWEYPKSDAEANDFVKLLQATRHALEEYSQSLPNRPHFLLTIASPAGPSNSKWLKLREMDQCLDFWNMMAYDFAGSWDATAGHQANIYPSQQRPQSTPFSIDPAVRWYVDNGVRPDKIVLGMPLYGRAFQNTDGPGAAYNGVGEGSWENGVWDYKALRRPNSQVCHDNQAVASWCYDPSSRTMVSYDSPQVATQKVQYIKQMGLGGAMWWETSGDQPRDHPESLIKITVEGLGGYGGKHMEQAPNVLEYPESKYDNLKGGMPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV32</accession>
    <name>A0A9Q8UV32_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767927.1">
        <property type="nucleotide sequence ID" value="XM_047911878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV32"/>
    <dbReference type="GeneID" id="71992608"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12730"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="150" mass="16773" checksum="097AAA07B0621A7E" modified="2023-09-13" version="1">MAPHHAPHLKRSATGTIKPRKSLLNLPAEIWSKIGRYAVDNAYTLTGSYFIRGESWPYQPGIIQASRALRQELLPYFLSTKIEVGGAPCDKLAIVAIGKWLHALEPDMRHLVRGIFAEGKPLEGEALEEYLRVWSWQEDSAGMMEVVFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV94</accession>
    <name>A0A9Q8UV94_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_12850</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 12">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768104.1">
        <property type="nucleotide sequence ID" value="XM_047911998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV94"/>
    <dbReference type="GeneID" id="71992728"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12850"/>
    <dbReference type="OMA" id="CALESQH"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 12" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="12"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="15">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO23738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="136" mass="14336" checksum="FE1CF04ACF165254" modified="2023-09-13" version="1">MTGGKSGGKASGAKSNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTTGTKPGKGPSQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWD9</accession>
    <name>A0A9Q8UWD9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Histone-lysine N-methyltransferase ASH1L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_14562</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <authorList>
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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</entry>
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</entry>
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    </evidence>
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            <fullName evidence="11">Zinc finger transcription factor ace1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01744</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755430.1">
        <property type="nucleotide sequence ID" value="XM_047900892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5E4"/>
    <dbReference type="GeneID" id="71981622"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01744"/>
    <dbReference type="OrthoDB" id="9368434at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="560"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="794" mass="86942" checksum="0E5B079BB310AEA6" modified="2023-09-13" version="1">MSSAASNPRRRPARSNKPDMTPSLIDSFQNMSIRKGDTFHPNSNTNKSSFWDPLESTSKSPSMPARSTTSPQSLEDLLIGAGERRVAQLLNKVDKAIATKSTVALGNVLSEPEVLPVPTFMVDRATVRGQSQRTRTRHHSHSSDSGIGTSVADSTESASDSTAKGSVRTVCSAPSAVNHQSFSGISDAVEEERGLSKYAADQIHKHIIKPILHEDSLREFHDLIKSVPSRIGDKEIKNLRDLEKTLIFLAPDYSRSPRKYLNFCERTIRVLHTTVTTLHESDQRAPTDRPYTQGYFLDLVEQVRLGLLSPESAAVVINIAIQIRRYAMILAATREKQAKGESSDAMDVTKDERVSLHGGVTHNGKPAELVRHLPDGKVISVATGQPISEEELASAGMNGKRPATDVDDEEVLRSMARRKKNAKPEIHTCEICTKEFKRPCDLTKHIKTHERPWKCSEPDCKYHEYGWPTEKERDRHVNDKHSSTPSLYHCLFTPCPYTSKRESNCKQHMEKAHGWNYVRSKSNGKGRASNVMRLHQGSMPPSPSSTMLTPLTPIAPSPLNQTWSESSRQGSMAPPPIAGPSNYGTPAYGTPALSQPSPDFAGHFNMNMNFDFNDMQNFPTSAFPITPAMSEERRASGSLSSHSAMFDGSSFDDASPFEYAMENYDFSNFTFPPSFTPNTNAGGVSTGAAMPQVSPGAHMDQTFTNDAVNLDEDYGYGGAVSGPSSDFTLFGPTAPAATSGDMFPSLPTESSWGNINIEAMGNNFGSHFDVNGAPALTNGDSTLEELFPELKKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L632</accession>
    <name>A0A9Q8L632_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755922.1">
        <property type="nucleotide sequence ID" value="XM_047900505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L632"/>
    <dbReference type="GeneID" id="71981235"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01357"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="101" mass="11293" checksum="AB3CF9FDB2227F51" modified="2023-09-13" version="1">MYIPITRYPFSADVSDICTTKPDATIRTCSRAISIQYSGHFSCAVDTAVAISLAVLFALLVFQVLEFIRNVVEVVRKWPAEPKQRVEKPAPALFMFIPDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6M0</accession>
    <name>A0A9Q8L6M0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756122.1">
        <property type="nucleotide sequence ID" value="XM_047901030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6M0"/>
    <dbReference type="GeneID" id="71981760"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01882"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="6">
        <location>
            <begin position="82"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="7">
        <location>
            <begin position="479"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="539" mass="58295" checksum="782200B4A62AE2B7" modified="2023-09-13" version="1">MLRTATARLPGAEVRALSFSPATGSSLQAPARSFTTAPSTSIIRIPARPRQSTPPSTASASASARTFTSTAKMGRKESDAFGEVEVDDKVYWGAQTQRSLGNFKINQPQDRMPPPIVRAFGVLKGAAATVNMNFGLDPKLGKAIQQAASEVASLKLVDHFPLVVWQTGSGTQSNMNANEVISNRAIEILGGQMGSKKPVHPNDHVNMSASSNDTFPTVMHIAAVLDFEESLLPALKNLHQAMKHKQEQFEHIIKIGRTHLQDATPLTLGQEFSGYVTQLEYGIQRIESSLPRLRMLAQGGTAVGTGLNTFKGFDEMIAQEVSKLTGKQFITAPNKFEALAAHDAVVEAHGQLNTLATSLFKIAQDIRFLGSGPRCGLGELNLPENEPGSSIMPGKVNPTQCESLTMLCCQVFGNQAATTFAGSQGNFELNVFKPVMIRNLLHSSRLLADGMNSFREHLVLGLEANEAKISSIMKESLMLVTCLNPVIGYDMASKVAKNAHKRGITLKESAMELEALSSEKFDEIVRPELMIAPKDVQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6Y6</accession>
    <name>A0A9Q8L6Y6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00883</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756240.1">
        <property type="nucleotide sequence ID" value="XM_047900031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6Y6"/>
    <dbReference type="GeneID" id="71980761"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00883"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="51"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="37835" checksum="7ACEA7F0AA467B49" modified="2023-09-13" version="1">MFRFLTRAPRSKPYNCCLLRKAQHLSPHHQVQHSYHQFLTMTEITHPTIKDGWFREISDMWPGQAMTLKVNQVVHHEKSKYQDVLIFESSDYGMVLVLDNVIQCTERDEFSYQEMITHLGMFSHPNPKKVLVIGGGDGGVLREVVKHESVEEAILCDIDEAVIRLSKKYLPGMSVGFNHPNVKVHVGDGFKFLEDYKDTFDVIITDSSDPEGPAEALFQKPYFELLHGALREGGIITTQGSENPWLHLNMIENLKKSVKTIFPVAEYGWTTIPTYPSGQIGFMVCSKDGKSNVKKPLRTVSEAEEDKLFKYYSSKVHEAAFVLPKFAEKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7S4</accession>
    <name>A0A9Q8L7S4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756837.1">
        <property type="nucleotide sequence ID" value="XM_047899477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7S4"/>
    <dbReference type="GeneID" id="71980207"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00329"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF1">
        <property type="entry name" value="OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="335" mass="36354" checksum="9D8D02725998D3C3" modified="2023-09-13" version="1">MSQKQWQTDQSRLDSLKFTTADVPKPKDGEVLVCRGDCNHHKSVGQPESLVPCSDACGTIVDAGNSSWKTGQRVGTIFNQSHLTGQIKEKDMATGLGLPLPGVLTEHRAFSADSLVAVPDYLKDEEACCLPIASVAAWMALNGMRPMGQPIKGDATVLLQGTGGVSIAGLQIAHAAGLKTIITSSSDKKLDQAKNLGADHGINYRTKPDWENEVMHITHNEGADIIFETGGTQTLRKSFDCIAFGGLIDSIGYLSGKEDDPKDRLNINVLALRRTVTLKGIINGPKDRFEEMMKFYAEHEIRPVVDRVFSFEQADEGLKYLFSGGHFGKVVVKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L849</accession>
    <name>A0A9Q8L849_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial metal transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756988.1">
        <property type="nucleotide sequence ID" value="XM_047900285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L849"/>
    <dbReference type="GeneID" id="71981015"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01137"/>
    <dbReference type="OrthoDB" id="435980at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000013">
        <property type="entry name" value="Cation efflux family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000010">
        <property type="entry name" value="Cation efflux family protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF15">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="123"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="473" mass="51853" checksum="B7FFB6B5D53ACB91" modified="2023-09-13" version="1">MPPLLPSQLARFTRCSAGPRLKVQHRVLLTVASASVSSHRRIPRSAPLRPSPRSPYQCSHIVHRIRTPTASSTPTAMASQTTQKRTHTGHSHGEHHHHHHHHHDNTYLTSTNKSDPGVRITRIGLYVNLGMAVGKGVGGYVFNSQALTADAVHALSDLISDFMTLATISYSLKPATTRFPLGYGKVESLGALAVSGILLSGGVMIGLQAVMALSQQFFPHIFELLSHTGIFEHAQNHGHDHGHMHLGPNINAAWLAAGSIVVKEWLYRATMKVAKEKRSSVLSSNAYHHRVDSLTAFVALFTIVASHFLESARWLDPVGGLIISGMIVQAGWGNTKSALYELADVGMDDEAREGAEKALETLLVGSDAKIRGVQGIKSGQNLMFEIEAEVPEDWSVPHSNDLEVEIRDAVQQAVRGTRRVNVRFVTKATSHAAFEDQFTKEDRATIEEGQHEDHDHDHDHSHGQSNGHTEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8K7</accession>
    <name>A0A9Q8L8K7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Class E vacuolar protein-sorting machinery protein hse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_00713</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STAM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757142.1">
        <property type="nucleotide sequence ID" value="XM_047899861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8K7"/>
    <dbReference type="GeneID" id="71980591"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00713"/>
    <dbReference type="OMA" id="QVYRDWW"/>
    <dbReference type="OrthoDB" id="10255964at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11805">
        <property type="entry name" value="SH3_GRB2_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16978">
        <property type="entry name" value="VHS_HSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF3">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="15">
        <location>
            <begin position="16"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="14">
        <location>
            <begin position="209"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="138"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="364"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="573"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO12776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="687" mass="76423" checksum="9F0958508510EA49" modified="2023-09-13" version="1">MFRAQANPMDDAVVKATDENLTSENWEYILDVCDRVSAKAEGPAQAMAALIKRLAHRNANVQLYTLELANALSQNCGPPLHRELASKAFTDALLRLAADRNTHAQVKQKVMERMGSWSDDFRSSRELGIMDQAYNKLRQQQPGLMPPSRPVKKEVSTEDRRKEDEELQMALALSIKDKGPAADTPATTNGNTQQPTQAPPPPQQGTTAATVSRVRALYDFAPSEAGELAFKKNDIIAVLESVYKDWWKGSLRGQTGIFPLNYVEKIQDPTKEELERDAQMESEVFGEIKNVEKLLALLSVGAEGGGRRGEREEEEVSELYQRTLSIRPKLIELIARYSQKKDDFTQLNEKFIKARRDYEALLESSMSQPQYQQQYPVRQRQPSYPPQHQQPPYAMQQPPMQGYPPQGPPQAQAYQVQQPYAAQSQQHLPPQSDVQRYYSPVPGEQPPQGGFPSPYPQQSGPPQGAANVPAPFHFIPGGIQQGAPQSAEIRRKPSPNALQGNILPTDPYGAAPVFQGQIRPNSIHTLNSGNPQELATGGYESPVDNRHSYPSAQFQQQPTQQPPAPNQAYEAYSQQPQSQPVQTQAQQTLPSHIRNDRDGLPSRQRTASFESPTSMYSTQQDGQHPPQQAPQQPSAPLPGIPISPGMQPSGQPPYQAYQPYQQQQQQQHPQARVPSSGNEGDPGDFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA71</accession>
    <name>A0A9Q8LA71_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758068.1">
        <property type="nucleotide sequence ID" value="XM_047901475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA71"/>
    <dbReference type="GeneID" id="71982205"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02327"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="38677" checksum="C152A8ABBFBB7478" modified="2023-09-13" version="1">MANLPGHGLPGPPPPNSLPAFLVPDSSSKLPIDFLTNSPVDSATSDDDGATDPTRHRDFADTDESANEHFLAEEQEDLNRFLELCSKEMQKWPGKFQIAEDILKAETAITNKPEETIASEEERFLKHMRTACHRHGVSFPKDMMVEVYQKARVVARNPKIAGATLAEMKALCAFLDPISSFYYAETRGKMFGSDLWSSDPDQNRKRYAPWTFAWSPVIERLGDQNRIIGGTRIPSTIHDLIGKVYLWLILSCDRFSGRLRVIRVISKHGVGGVEALRKGEQHRSYARLNILGSATESDPPLTYGPFKVRPIAAKYPRMDKDSMLDLMVDNRSLSDLWCCTGLKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAD6</accession>
    <name>A0A9Q8LAD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Unsaturated glucuronyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02702</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758184.1">
        <property type="nucleotide sequence ID" value="XM_047901850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAD6"/>
    <dbReference type="GeneID" id="71982580"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02702"/>
    <dbReference type="OrthoDB" id="2317065at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040251626" evidence="4">
        <location>
            <begin position="18"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="480" mass="52916" checksum="3F2BE42A93A80719" modified="2023-09-13" version="1">MKLRTVLWLSLCSSGFASRLHPPAALHDDNMGARILRTALIDPPTGDSQSWPMYTYGAHDNIPPSDTIPGTYVKTTASGWTAGFFPDSIWHMYHRAKQTRPSHRQDATSSGPTPDEWLTLAHQWTAPLTSNANLTTTHDLGFLAKPFESALRFNNETHYLPILAQMSSSLAARFVPEAGVIRSWDNKNTSFSQNASHQDSVLVTIDNMMNLALLARSAAEYTGNATMLEMAISHANRTRDHHFRPDGSTFHVCDYSGTTGDLYLCRTAQGLADNSTWARGQAWGIYGFAEMYSFVQDPSYLATAVKAADWFLDHLPEDGVPFWDFDAPRIPDVTPRDSSAAMIAASGMILLQDQIDRTSSRGPAKDGRGERRSRRRNYPDAAIKLLHDTLDLTLAGQIGYADIDKQHPASTLGATTDPTTPANTSVSRGFEAILMHATANNNPSAGDERNFDTGLLYGDYYLIEAGDRLGYNKCKEFKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAU1</accession>
    <name>A0A9Q8LAU1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758398.1">
        <property type="nucleotide sequence ID" value="XM_047902603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAU1"/>
    <dbReference type="GeneID" id="71983333"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03455"/>
    <dbReference type="OMA" id="RIVHHSG"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="97" mass="10469" checksum="C07734BDC62F7EB2" modified="2023-09-13" version="1">MAPAATGGKKQKKKWSKGKVKDKANHAVVLDKNTGEKLQKDVQSYRLITVAVLVDRLKINGSLARKALNDLEEKGVIKQVIGHSACKVYTRAVGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB66</accession>
    <name>A0A9Q8LB66_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_03798</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758507.1">
        <property type="nucleotide sequence ID" value="XM_047902946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB66"/>
    <dbReference type="GeneID" id="71983676"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03798"/>
    <dbReference type="OMA" id="WGWQETK"/>
    <dbReference type="OrthoDB" id="200187at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011553">
        <property type="entry name" value="Sec62_asco"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00869">
        <property type="entry name" value="sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="330"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="408" mass="45598" checksum="610DB6E1733E7AF0" modified="2023-09-13" version="1">MAQPQPQQVPPGAEQGGPPPGMRQMQQPSPEQIRAMQQQLAADAEKAGMSVPDYVEKMKAQYMHQAQRHAQQQQHQQQQAQQQQGQHQHGPQGAQPGQQVPIAPGPPKPEGLAVAHFLQKQDLKPRTCILNQQRKDMFKVKRAIRALQSDAYVKARKKNPILPEVKDRVTAENCFKTLPMSLLALRVSKIDPHEGHDHGKKKRTKGLWTVKVEPQQEASDEFYYVWLYEGSQWKNKLYAAGALALILAVVFFPVWPVKLRIGVWYLSMGMLGLLGLFFAMAIVRLILFLITMFAVPPGLWLYPNLFEDVGFFDSFKPLWAWHEDDKAMKKRKKEESLRKKERRALKAAEAEGKKGKKGEKSEPVVTTGVASATAPVESTPASPAEEAPASGGQAVEPQKASVEEGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBC1</accession>
    <name>A0A9Q8LBC1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBC1"/>
    <dbReference type="GeneID" id="71983062"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03184"/>
    <dbReference type="OMA" id="RHRARWI"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="42783" checksum="329B50F420F54A5E" modified="2023-09-13" version="1">MARTATMVARINDDTTNEPATPSLFDPEYLRHRARWIRDILDPQVAQEGANALHSDEVLTLDELLRRLLDHDMSLADIRFTRMHLAISEISGKATRWPKKLIDRCEAIKVVWEARYGPLKTLGTPLYEPGGRLHGICRPEDLNKEKLLVKWLQSPAAKLSPSVSRKVGDLGFTPGDWWISPMFAYRAGIIDSGNPAGGIVSDSDGAYAVVLTDSDEVSGNDPNHFQYRARDGDPGRYRLTAATPESRQPVRILRSHMLHSFLKPRAGIRYDGLHKVTGWSLKKDVKTNKTVFIINFKRLSSELSMEAVLCRPWSDEVEDYSEYKRLRQEQRDKQKDAPPPVPITTSDGANDHVWASTSVAVVLPATSGFTVLHPDGGRDPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBI5</accession>
    <name>A0A9Q8LBI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758733.1">
        <property type="nucleotide sequence ID" value="XM_047902511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBI5"/>
    <dbReference type="GeneID" id="71983241"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03363"/>
    <dbReference type="OMA" id="IQLFDWS"/>
    <dbReference type="OrthoDB" id="8064436at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067:SF1">
        <property type="entry name" value="MITOTIC APPARATUS PROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067">
        <property type="entry name" value="YALI0C15378P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58022">
        <property type="entry name" value="XRCC4, C-terminal oligomerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="42828" checksum="A30DFA00C572383A" modified="2023-09-13" version="1">MATSRREELLRLKRTDHKTEHLVLHVADHSTSPDTLDLKLVGTDTERLYHGNVEESSLETLQASNFKGNLAEFKTVLSYALLHQLPKGPFPDVLEGVETVAAVDIKTFTVTIRKNISGITQKLAAIKLEEDTGNIEVNFIGWTDEALIDRDDLRARLADTEEHMKEQQAQVAQLSAELDKLVKAKKQHEEEMLSKFAALLNAKKLKIRDQQRLLSSAKVDFDAVEEVEQARLSNGTKRVGASRKGKRKAHGTVEPAAPEVEDEGEDDATADGTDDAQEEDRRRQETPETDEEDLADEDLDVEGDSSGMATAIDDSQTTRRVATKATRKGHRGQRSSQKINADKQKSPSPQRKLPSRKAKSPAKEPTPPAPSNDVDDVDDDETDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFN8</accession>
    <name>A0A9Q8LFN8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04976</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760963.1">
        <property type="nucleotide sequence ID" value="XM_047904124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFN8"/>
    <dbReference type="GeneID" id="71984854"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04976"/>
    <dbReference type="OMA" id="YDLNMQV"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00075">
        <property type="entry name" value="HATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000100">
        <property type="entry name" value="Sensor histidine kinase/response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF2">
        <property type="entry name" value="HISTIDINE KINASE M7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="531"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="771"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="702"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO16597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="910" mass="100013" checksum="EEFCCB02D6240646" modified="2023-09-13" version="1">MSASSGEQPDMDRTTICFPQHGTQDVLQHGNPRFERELARLYSPAESRALEQLIELKKSLRQLSTDDFWGALTEGMCKILGAELCFVMKRVLVDDQHSAVEMPPLGEPGACMMATALHYCGRDGTRNTAKQTKFHAYGCPCAYMRHDKVFCIPDRLNEFITNNPNTLPTPCDAYMAVPLFEDSKCFAHFGALWSAESAAQKPLSWAFTELMMHSLEDMIAYTLLQGANFVKPAAALTEKSRIIPHDAVTVAQSLRPYAGSLSHELRTPMQGIVGMLDVMMATVMEAAETQSDPRVRKVFEALKDNIEVVQDSSRRAVEAADNVVHAYDMDLSVPELSLPLSEESADSALPFSATADRRPEILVAGHNLPLARPNKRRRDDAFPQATSRNTSDSNLTNKLARLSRGPSSCRCSEPDVKQGVPQALDLHKQSVMGAELADVSTDEDAELAREVYSGASRIIAPGLRHTSLGDLLQHVINEGLKVGGRPDSAIAVETARGEIIEVRTRGSDGTAGFKTIEWSLDPGVPSTMFIDERDLSKLISCVFLNALKFTDKTDGLIKVDVKLSNRSRYISIRISDNGPGIPAAFLPRLFQPFAQENGSITRSSEGLGLGLLVAKGIARKLGGDLMCLRAETTGSNRGTEFEIKVPINAGDTISRPASPYRSPVPRPARPAMYESQHIRPLPAEPGSPRKLTRALHEAVFQNTFSRPPTMVSPSTPPSPKSHIGVEVASSPPISLPSPPSEREKASARRRVRKSVMNPEIDRTLSTRFPLNFLVAEDNKINRKLLVNMLSKFGYKNIYEAHDGAEAVRQMCQPRDEDKHIDIVLMDLWMPLMDGYEATERILSMEGVQQSRKPTVLAVTADVTDSALERAAGVGMKGFMTKPYKLLDLQRLITEYCASHLVDETLLAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG19</accession>
    <name>A0A9Q8LG19_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761094.1">
        <property type="nucleotide sequence ID" value="XM_047904454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG19"/>
    <dbReference type="GeneID" id="71985184"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05306"/>
    <dbReference type="OMA" id="WLHETYC"/>
    <dbReference type="OrthoDB" id="5067658at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06222">
        <property type="entry name" value="RNase_H_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044730">
        <property type="entry name" value="RNase_H-like_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="181" mass="20263" checksum="D4B886D2B3B142E9" modified="2023-09-13" version="1">MPLKPDLLIWTDGSRHREQGFSGCAVVFGGKLWKNPRLGSFGVSLGVQPSADVAEIYGHIYALRLALWLHETYCPPREKRFFDRVVIVTDSKFTSDHYDFLLFSASPAQLAAAPAIVQEAVGLIRQILKLGVGVEVRWERRDSSHGNREADRLAGVASRIANKGYGVEEWVEEIAVREEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGL7</accession>
    <name>A0A9Q8LGL7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761160.1">
        <property type="nucleotide sequence ID" value="XM_047903604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGL7"/>
    <dbReference type="GeneID" id="71984334"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04456"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040360226" description="Fungal N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14236" checksum="AD15750FFC540A87" modified="2023-09-13" version="1">MDAIGSVSAVLGIALFALSIAKQLHEVIDIMKDAPDSVMTIARDAHDFHAIMESLHTILTERSVNYLVERHPTFRQQVENLKRPIQHCCELVSSVTTELQLWFACQSGGIKKAAKRVRFYDAPSVATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGZ0</accession>
    <name>A0A9Q8LGZ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-dependent monooxygenase asL4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761355.1">
        <property type="nucleotide sequence ID" value="XM_047903738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGZ0"/>
    <dbReference type="GeneID" id="71984468"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04590"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF2">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="5"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="44503" checksum="1F9D6F60C85191E9" modified="2023-09-13" version="1">MSILKVVISGAGIAGPVAAYFLAQANAEVTVIERAPAPRRGGQNVDIRGHGLTVLQRMGVEDAIRAKTTEEKGLRFVDADNRSWADFPVDDGKGFTSDIEIMRGDLANILYEHSKGHVTYRFGDSVRSFSEDDEGIDIQLESGKTIHADVLIAADGWNSATRKLAFGSDISQSSVNDLGQWTAWFTIPPSPSDSYWARWYNAPGKRMVLIRPDAGRSSRVSLWVMPKDDKLDHLVKADMAEQKAHWLRLFQNAGWETDRVLKALPQADDFYMQKVAQVKLPSWSQGRVVVAGDAGYCPSPISGMGTTVGVVGAYILAGELAKQPNDVAMAFKSYEERMRKFVDIAQKLAPGAPSLANPDTAWGIKILYTFLGFVAWTGILGWFGASFNPPATAIELPGYQFESKPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH06</accession>
    <name>A0A9Q8LH06_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761650.1">
        <property type="nucleotide sequence ID" value="XM_047905105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH06"/>
    <dbReference type="GeneID" id="71985835"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05957"/>
    <dbReference type="OrthoDB" id="10336755at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="19292" checksum="C6330BAEC05E67F4" modified="2023-09-13" version="1">MTPPTATSWQRLMQEGDAQLREGDTLEPNPANGGGTTTSRHEPRHEPDMAQTCPSFTPGQQGRNMITNVPQQPRSVSRQNVGAASSASYDQQHASRVFGQHDEPQSMQLQNSISYGPLPRMPTYESGAHQTLRQLAPKLQALLDLFATAYETHDMVKVEELRRRLNWAIDAKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHB1</accession>
    <name>A0A9Q8LHB1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase BRSK1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761792.1">
        <property type="nucleotide sequence ID" value="XM_047904908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHB1"/>
    <dbReference type="GeneID" id="71985638"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05760"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF76">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="282"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="189"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="66644" checksum="1E1539A19DCEB58F" modified="2023-09-13" version="1">MVPASHGEPSQPAAPNSASPKSRHSRPAFSSEDDPSPFVQPSSPMMAGESLLARHLSAGQDHSVRQEQADRESQSHHRDAPRIHKPKTTRWLIGSPSEDRLDSMTRSSSRRTRSPENQSPDLTATPQPTVTTSNLERLPTASLTSASTISQSDVLGSPSSPQNLGSLADSIESIASKLVVSPQTIPETSTIHHSLPSPLMSPSASFVDDPLSRHSSTRSMRVPRSQRGPPTRRSSRRSESTHTSSSPAHAFLSSWGKSNIEEPPPEPKPDDEGQSVGLNNEYIVGRTINRGGFGVIKEVHSIDESGRRTMRAVKIVRKAIQGVSESLNEKAQQECEHEVSIWRYLKHRHVLGLHAVYETDFATFCVMDLNVGGTLWDLVRKTRSDAAKDSARKGLAPRLARSYAFQLACALRYLHEDIRVCHRDVKLENCLIDMSAPNADEKGGNLRLCDFGLADFLHSSSIDEGEPPTERFSEHLSLSTELPVPTVSSIIGTLEYASPKGLTVNRKLFETAGDVWAFGVIVYALCTGNLPFRHPMPSKTAELILRADWDEAALRDAAAGGPDVIDLVKGCLEKDLDMRFTISDALRSPWFEGCYEELEEETTSGGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHE1</accession>
    <name>A0A9Q8LHE1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761837.1">
        <property type="nucleotide sequence ID" value="XM_047905634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHE1"/>
    <dbReference type="GeneID" id="71986364"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06486"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="49991" checksum="E6BD6A9650AD1F46" modified="2023-09-13" version="1">MTIYDIQFAVSTDGAIQKIAHSIIESVDMSLGTLHILTLLHEPNKVHYGQEPICGTVSVRYTTSKLKDKEHAELFGPLKIRLRLMGSVEIGRASDVNNTKVCLKVDTIHDGPVKLMAGSLTQYPFEITFPPHADPKINSAVSAQQAENGDWKFHQRTTSVHTEPLPPTMRSSEREGISKRETAIRYVLAVAAEMPGFSVEIIHPPLPKEVLYDQPRMPTSATAMLSERAPRSKQKLVVRDEAFLGEEARPQGFRGKAKAILKHEEPPRYVFEVYFENVPKHIFVGQPVDLDLSVASNSEQSTAASFPPVSLQSASAALIAHTTSPRSSFDASDLVMSTETLKAKEAEIHPKGSFDKSRDHTKTISFGALSYVPSSFRYADIVSRTYKLRLMLAFLVCGQTVNCMRQFDVVVHPPLLLDEDEQPPSFDAVFEEDLPSYDEVVAGPSTASYLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHG2</accession>
    <name>A0A9Q8LHG2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase tropD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761921.1">
        <property type="nucleotide sequence ID" value="XM_047905535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHG2"/>
    <dbReference type="GeneID" id="71986265"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06387"/>
    <dbReference type="OMA" id="LSYPPKW"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="494" mass="54668" checksum="CC2BB06CAF3AE433" modified="2023-09-13" version="1">MATSIIQTPQGLLFAALAILTAALLYAQVKSYARLRHIPGPLLASLTDLWSATKVWRGAHHCEIVHELHQKYGPIVRFGPNRVSFANPDTIPQIYGTGQVFPKASSYNPMRTLANGKEIMSLVTISDEKKVTSLKRHISAGFSQSTWLKQEAQIDGTLKILITQLRARAGQEVPLNTWLSFWSFDTLTELAFSESRGFLTAGRDLDGICPSGHQRFAHWRLWASLPGWEAVIYKNWIVTRIQRATGPLAQLAIRRIQQRKAEDKAGGGGKDLLGRYLAASQEAPEAVAPADVLGLTISTIHAGSETTAMTSSATLVYLLWNPATLARLEEEVLGAGLSFPPRFAEVDKLVYLDAVIREGMRLFVNPNCVERTITPPGAEIGGVYLPAGTGVSISELDTTRDPAVYGADPHSFKPERWLNVDKTKWAEMNRVSFGFSYGRRECIGKHLARMEMKKLLASLILSFKIVPTKPVQMWMESSLGQTRLDVRLEPRVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHL3</accession>
    <name>A0A9Q8LHL3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_04244</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761144.1">
        <property type="nucleotide sequence ID" value="XM_047903392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHL3"/>
    <dbReference type="GeneID" id="71984122"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04244"/>
    <dbReference type="OMA" id="NFVQFGR"/>
    <dbReference type="OrthoDB" id="2015537at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="33"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO16778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="425" mass="46560" checksum="8317DCF88FE4A0B1" modified="2023-09-13" version="1">MPFDINKCARPNILALEPYRCARDDYKDDGTNILLDANENAYGPGLALSEDGKLANGHASNIEIDLLGLNRYPDPHQHELKKMLCNLRNTHAHTKKDMTPENLFVGVGSDEAIDALLRAFCAPGKDKILTCPPTYGMYSVSAHVNDVGIVKVPLDVDNGFRAQPDKINEALAADPSIKMVYLCSPGNPTGSLVRKEDVQAVLEHPTWNGLVVLDEAYIDFAPEGSSLAEWVAEWPNLVVMQTLSKAFGLAGIRLGAAFTSPEVARLLNSLKAPYNISNPTSQLAIQALQQQNLQVMHKNREQIIQQRERLLQEMPKITGVGKFLGGTASNFLLLEMVDTQGKPSNEVALQVYERLAEKRGVVVRFRGKEPGCLGCLRATVGTEAEVTRFLKELKSVLEDVHAGRVSAASKVREEQKENDANGIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHS1</accession>
    <name>A0A9Q8LHS1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucan 1,3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762055.1">
        <property type="nucleotide sequence ID" value="XM_047905555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHS1"/>
    <dbReference type="GeneID" id="71986285"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06407"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000023">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000026">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040265798" evidence="1">
        <location>
            <begin position="20"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="120"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="469"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="849" mass="90798" checksum="22B0428D9A7706B1" modified="2023-09-13" version="1">MHFSSPLIPFLFAAGSAQAQLQGLLPGLPLPLDLGGLHLQGGGYEPPVVEQLGNLALSQFSKYTAYPGPSPTATPKQLSPQMLAAAAATSVASQCDYWMENIKHQGIAAFNSNPSGYQVFRNVKDFGAKGDGVTDDAAAINRAISSGGRCGPGTCGSSTTTPAVVYFPAGTYMVNSSIIDYYYTQIIGNPRCLPTIKAFPKFTGGLGVIDGNQYGANGLGFGATNVFWRQIRNLIIDTTLVPASSSITGIHWPTAQATSIQNVIFQMSNARGTQHQGIFIEEGSGGFMNDLKFYGGLYGGNWGNQQFTMRNLTFDGVQTAINQIWDWGWTYKNININNCSVALNIANGGSNALTVGSVTFIDSTISNTPVGIITGRQQGSQPSTAGSIIIENVKLNNVPVATRGPNGPLLQGTNYISAWGQGNSYTPNGPSVINGQIAANNRPSNLLQGDGKFYERSKPQYEELPLSSFISARAAGATGNGRTDDTQALQAAITQAKSQNKVLYLDHGDYLVSSTIYIPAGSKIVGETYSVILSSGQFFNNMKDPKPVVQIGKPGESGSVELSDFIVSTQGQQTGAILFQVNIASPSGNPTGLWDVHARIGGFAGSKLLLADCPTTPGTVITSANLKQSCISGYITFHITKYATGIYLENTWFWVADHDIEDPTLRQITVYSGRGLLDQSAGPVWLVGTSVEHHVRYEYQFANAKNVFQGQIQTETAYYQPNPIATIPFPRNDTIFDPQFTQATVSDGNTVIPAADGWGLRILNSQNILTYGAGLYSFFSNQSTTCSDQGQGVRCQNRINSIEGSSSGISIYNLNTVGTHWPITINGTDVAKWDQNQGGFIQTVALFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHW9</accession>
    <name>A0A9Q8LHW9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-dimethylallyltryptophan N-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.261</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06565</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:34435"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58209"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:67248"/>
            <dbReference type="EC" id="2.1.1.261"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis; ergot alkaloid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.261" evidence="7"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762161.1">
        <property type="nucleotide sequence ID" value="XM_047905713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHW9"/>
    <dbReference type="GeneID" id="71986443"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06565"/>
    <dbReference type="OMA" id="RVEMHLV"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="10">
        <location>
            <begin position="45"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="20"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="356" mass="40655" checksum="76C47126DE572DBD" modified="2023-09-13" version="1">MQYIGKHPFPIASWPLARSKSGKYSTDIKDIRPGGQRFDPAKPLRDGLRKPDGNGQRSFDKLFLRGQQGNKDFDQNIDSPDSHLQDAEIELLPSHSAELAETLPAGTTLLEPGSRSLRRTNLILQAIDSQHKIVDYYALDLDQNELEQFLRELDPGRFKYIRCHGLIGTHDDARAWITKYENKQRPISVLSLGSAIGSMVRSEASKFWLEWSGALRKNGDQRDCHIIIAIDSCKGGGKVSKAFRDEEGRSARFTANVLDRANRQLGKQIFQHEDWTQQGEWEAESGRHSQYLVPQRDIDFEGTTLVKGERILVSHSHRYDDAEKQRLWEDVQLKEVRRYMNANESYGLHVLSLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHX4</accession>
    <name>A0A9Q8LHX4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762145.1">
        <property type="nucleotide sequence ID" value="XM_047904907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHX4"/>
    <dbReference type="GeneID" id="71985637"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05759"/>
    <dbReference type="OrthoDB" id="4153866at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350382" description="Altered inheritance of mitochondria protein 6" evidence="3">
        <location>
            <begin position="22"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="326" mass="36405" checksum="771D3C5F6269C5C1" modified="2023-09-13" version="1">MTLGMIHLVLVIAGGSHFYWSFNDNQLLPDWGLPGHPGAGLVHYPTDATRDVLPIPVHSHSDYWRSRPLCDALSWGCMSVEADVWHFPGDSELYVGHKTRSLTKDRTFRRMYVDPIVELLDVMNEAAGVGDAGDYNTTRRGVFDRDPAQTLVLMVDLKTAGADTVDAVSTELAALRSKEYLSHWDGSQLQIRAVTVVASGNTPFDQIIAAGQHRDIFIDAPLEDLSTKSYNASNSYYASVSFKKAVGHVWNGQLSSEQMRTIQNQISEAHQRGLKARYWDTPAWPINLRNHVWDVLMSAGADVLNADDLKAAALSDWKRRVHGLWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHY2</accession>
    <name>A0A9Q8LHY2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761850.1">
        <property type="nucleotide sequence ID" value="XM_047905422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHY2"/>
    <dbReference type="GeneID" id="71986152"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06274"/>
    <dbReference type="OrthoDB" id="4790878at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="207" mass="23640" checksum="AE9F3FE53A4680EC" modified="2023-09-13" version="1">MALQTASAMQDPSIPSADGTCHLLRLPRELRDIIHELTLLGNPFPIGPYIGSDMHKRLLHWLVRGFKTSPNYCTFFLTCKTLHDEVLCAYFATRTFYCLYQSQLISWLDALPTGYRSALRSIRVHPEVFVPESKDPLSFRWLKLNHDGRAQAAAQELSLLEAFRVELEAQGIFLKRGVLKANVWVGKGSTGRFNPWNLEFGIFEWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIB4</accession>
    <name>A0A9Q8LIB4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_06358"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23982" checksum="17A30DE0C31DD8D2" modified="2023-09-13" version="1">MASSLEQLPAELLDRILCHVDIELPEKGVYFERERPRLQETRRLSLVSKTFQKATGPLLYRTVDFLHGNHARRLLRTLSTKPYLARYIKEAPFQGHVCETEGPPSERELTAYSTMLESAGSQDVRNEVWTGLKRGCHTAETILITALATTLQTLYFSLYHSSGSSGNHADRSGASKGCPHTTRCLDKIIAMSDDHDSKRDNNLRKVQLAGIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIW5</accession>
    <name>A0A9Q8LIW5_PASFU</name>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIW5"/>
    <dbReference type="GeneID" id="71986420"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06542"/>
    <dbReference type="OMA" id="SATCEDE"/>
    <dbReference type="OrthoDB" id="2730545at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="213" mass="23794" checksum="3E3101EF70CC7618" modified="2023-09-13" version="1">MGIIEQQNAAIGNAVLDINEYPQLRLTAAATESGRDVHEAGVEQTWKSALVLLPAMQWNFSSERSPSRNDFLPELQDVVDAFIDSLLDSAADSGLRTCLNVQLAYLYGNTQELESRDFAYRLLYEHRQYHYDICAGMSYGTVPFVEHQRKIRQALRDGTLELQECSAARDDEGLFREAAEARLLASLPPVLVSDSKSDEEDGSGISMDEREDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ24</accession>
    <name>A0A9Q8LJ24_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_05645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
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        </reaction>
    </comment>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
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    </dbReference>
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        <property type="entry name" value="E3_UB_ligase_RBR"/>
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        <property type="entry name" value="IBR_dom"/>
    </dbReference>
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        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="131"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
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        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="48601" checksum="1E918BA0B96FEF04" modified="2023-09-13" version="1">MAMAGDEQDEYHAAITTDSNVATAATHPHDDGSGLKRKRPDQEADETEDTGPAAKCVKQYGDPASTESSVATTATQPHCDSSTRKRERSDEDGDEVEDIAPAKKCIKQDGDAYAGARLIKRKRVPEGDRNGKVKCETCWDRKPVEEAIALECDHTSCYGCVQDLFRQSMKDETLYPPRCCTRLITLDDMRDILPEDLIPEFIAKREELEDPSKCYCHVPTCSAYIPNAKRTGDNAICPTCNSSTCRKCQGASHDGDCVYDPETQALMETAKDLQWQRYPPCGRFLEHNFGCWHMTCPCKHEFCYLCATTWKECKCDLWEEERLLERARIITERERLGRATQGRRNARGRWIPVQAPDGAPRDIAGMAARFRQHAECAHGNMHMYVPGSYECDDCHHVLDRYIHRCDQCRVSLCTWCCMHRRRRGAIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ92</accession>
    <name>A0A9Q8LJ92_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulatory protein alcR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_047904896.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ92"/>
    <dbReference type="GeneID" id="71985626"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="61"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO18400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="915" mass="101603" checksum="6D18B4009281BDC6" modified="2023-09-13" version="1">MALPGTATASKRTAREMEMDWQHGETACYSPLSECTDATGRMYSEDECKDAAIPRRRQNRSCDHCRLGKRRCDVRIKAGDLSTFTPCTNCKRWKKQCTIEWIKTRERNPPIPTGGRPRRKSTAGTGSELPALQETTSETWSPMGSSSSSSEFRLNEGINIPPRRINPHITLDSSFPWSSAGMAGPKILPDMRQNVPGPDTQLFPHDGGTAACSPDLAGFASSSAMASMGSSTFNDPYERPAGHFPPIPVPLVPADVEPTLPLSSNPAIGTSSIANASAPIEPQQHMVHSGYITDEQNNDVPGQEDGRLTPRTAIRYNLFRPSSPFAMQFLAKDYSRIQIKEGLLKIYRDSMEGALSCWLTERNCPYSFSPFNGKDLLDGRDVWGSNWASRMVTRVCALDKEYVKAGVLSKRDQQQGAKILNLVVMAFAAQWSQAGRRHDAAHTDYSSSSSESAAATGQACSDPPIQQLGEESFGRNTQKALWHKANRALSEASDNNSFQAVFAGIIFSLTQRPINGTEVLDELQPSGTDELTSLFKVLDLDGPTLSLDAANRKMHDHRRKLRDAKQPGMYGARAPIKLSDAHEETFGLLYWLAVMFDTLSAAINRRSFTINDMESNFSRAGGDSKPRTVRHDSGLPQGYMLPEQELNDEAAVWGDYFLREQSRTGQLRSQSTRWPCQYHEAASCLADAAPVKVLLYRRLGQVQSLYYQGALPQLIENGLEATMEVYNHWNNTYGLFIEDCMRYHEELPARIQSWYTLLTGHWNLAVLIFVDLIDTMDSANMTLPTHANLRKSISFTSHLRDTAVYAICELGRCCRAGDEPLAFTQSPDFHHAVNKAALLTEPWTVVLVRTFGYAGAILARRLHLDQPPESGLALGTYSKERLQYCIDALSLLGKKSDMAMCAAELLSRYTNRSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJF3</accession>
    <name>A0A9Q8LJF3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07543</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762887.1">
        <property type="nucleotide sequence ID" value="XM_047906691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJF3"/>
    <dbReference type="GeneID" id="71987421"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07543"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09299">
        <property type="entry name" value="TDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="893"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="927"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="958"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1055"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1087"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1116"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="10">
        <location>
            <begin position="94"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1160"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1160"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1178"/>
            <end position="1194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1194" mass="131778" checksum="EAABE9D39BF5F7A3" modified="2023-09-13" version="1">MRLDHSNDRTQQRPSTNGSSQNGSSPRTNGSVKSETNGYHTNGHTEETVATRSKEPFYGHDREEVTRILLQSLSDLGYRGAAEKLSRESGYELEIPSVAAFRNAVLSGEWDEAESLLFGQSSDELDGGGVALENGHTSSTSRRKSGGGSLSLGSQNGFARNGLPFAEGVDTTYLRFHLRQQKFLELLEQRDLNAALNVLRNELTPLKTDVARLHFLSSLVMCHSASDLRNQAGWDGVNGQSREVLLSEISKSISPSVMIPEHRLATLLSSVQEEQILNCRYHNTIANPSLYTDHECSPDDFPLHQQLELRNHSDEVWFLEFSHDGTMLATAGKDGLVCVYDTVRWRLKHEFREHERHPDPRSSGSGDMRGVCYIAFSPDDQYLISCSQDTTLVVVSVRTGQRVALADHFDYPVTTAAWLPDSETFVVGTQGSRRPLGLYSLRGSSSSSNSGIVKNNEIHSWREPPWDPSLKDNQPSSFRITDCAVNKEGTLMAATTIDNRIMQFSLGHNMRYCKVSEWQMEDKLTSINFSDDGDHILINMNEGRVLALDSGNGEMACSYKGAVQKEFVIRSAFGGAGQNFVISGSEDSRVYIWRRQTGGLVVALDAHHPGTVNAVAWHPTNPGIFASAGDDRRMVISIGKKKTNSIRSMVRSNKAFKRRRRAVLLFGRTVALTAGMLIFDYTDCSHRTDIMPSVPQWSTSPAATRLRGHDFNMTYRDQVHARSSTDSHLQHHQAYSYIILGNLIAKLQHYLAVSHSRQVITITMTDVDIPTDEPQRVSPWRIALKSFSSQWILVPQGTGILSVILHQLHYRGEWLTRISQVFWVLTIVLLVGFLLTYLTRCLLFPKEVARALRRDLQETVCLSSISITFTTVIQMIALNLTTDWGRGWGMAAYVLWWINAAMATVACLGTPYVFTKLEATSVDLVPPGMLLPLIAALTAAAGGGVVCRYGEVGADLEVPVIVVSYLFVGLALPMSVVVDAVFWVRLMDGKFPVKEKEFQLMILCGPLGQGSFALLILGQCVQRGAFATDNASPFLGASGGATIATASQFLGLLTWGYGIFWWAFACIAVLHFLIAAPRELLQMSRTLAAWSMVFPWGVFTNGAIELGVILNSRAFWVVSTILTIILVILWVVNAGATVVGVLGGTLLSLDGGWKAQYVEKKERSSDSGGSDDGRRNGYVQTNGSDSNGLRNRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJH2</accession>
    <name>A0A9Q8LJH2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxybenzoate 4-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762901.1">
        <property type="nucleotide sequence ID" value="XM_047906216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJH2"/>
    <dbReference type="GeneID" id="71986946"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07068"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF4">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="46"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="337" mass="37633" checksum="A8FE801535B3A8BF" modified="2023-09-13" version="1">MATNRKREALGQNGDLHQPKAQKHNSNMSPGRLQAYHEGANDYNGYDVAVVGAGLAGLMLAANLVRFSIRTVILDDRPDKTSTGRADGLQPKTIETLRQMRLADGLLKRAARIYDICFWSSSPDSPMRRTGRHVHYPPVVDLLDPYILLVHQGIVEDVFPDDLRDRGVEVRRSAPFMTYEETPGQDRALNVLYDNQGNRRSIRADYLAGCDGAHSQVRKCIPGAVAEGSSSKAIWGVLDGDIDTDFPGLWSKAVVYSHKYGNVLCIPRESNLTRLYIELKLEDGERLPKEKATQEYVMERARAILQPYTLSWTSIGRDIVQASELSANVAAEWFGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3J1</accession>
    <name>A0A9Q8P3J1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the hexokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756215.1">
        <property type="nucleotide sequence ID" value="XM_047900979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3J1"/>
    <dbReference type="GeneID" id="71981709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01831"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="10">
        <location>
            <begin position="226"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="58717" checksum="60653E3309F3669F" modified="2023-09-13" version="1">MALAQAAERVAAEFEYPKEDVNRGVKEFIRQMDEGLGKTGATMSQIPTYVTAVPNGTEKGLYMAVDLGGTNFRVCSIQLHGNSTFSLTQSKVAIPKDLMVAKTSHELFAFLAKQIELFLKTHHGEHYQGHKEKKKSFMSERDEEVFSLGFTFSFPVQQSGINKGTLIRWTKGFDIHDTVGKDVCALLQQEIDALGLPVRVAALVNDTVGTLMARSYTSPGKTGTLLGAIFGTGTNGAYVEKLDKVTKLNNLGAEAGDVDRTTGEMIINTEWGSFDNQLSVLPNTQYDRDLDRESVNPGIQMFEKRVSGMFLGEILRRSLISLLNDKNVPLFTDEHSNQNDVHSTTNVDKDSPLYKQWGIDTSFLSITSGDNSAGLKVTRQTLDKEYGVTAASSEDAEAVRLIASAIGKRAARLSAVAIAAIVIATDKLKKPTDISTTNNASLEVNEDDVVDIGVDGSLVEFYPRFEEYIREALRDIPEVGPEGEKKIRIGIAKDGSGVGAALIALVADKAMKISAPSTSSGGGFLQSLISNINRSIRYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P469</accession>
    <name>A0A9Q8P469_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mannan polymerase complexes subunit MNN9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757024.1">
        <property type="nucleotide sequence ID" value="XM_047900160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P469"/>
    <dbReference type="GeneID" id="71980890"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01012"/>
    <dbReference type="OMA" id="IPKTREG"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="376" mass="42535" checksum="03FFA45980A99835" modified="2023-09-13" version="1">MAVSRGIRRTSPITYVFATILCIFFLYFFFGDSANIPSIAAAPRQLLKSKDAASNELSPPSLPFRKPAVLGPNEIAPPPPVVHYQMNNVTITADPVGNRESVLILTPLARFYQEYWDNLCKLSYPHDLISLGFIIPKGKEGNLATQQLQERMQKTQAPTNKNRFASITILRQDSEPPVEQTEKERHAMAAQKERRAAMSRARNSLLFTTLGPTTSWVLWLDSDIIETPPTLIQDLASHDKPIIVPNCFQRYYNKDKEAMDIRAYDFNSWQDSSTAQSLAAKMGPEEILLEGYAEIATYRSLMAYMAEEKGDPRKEIELDGVGGTALLVKADVHRDGAMFPPFPFYHLIETEGFAKMAQRLNWKAYGLPNYFVYHYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P475</accession>
    <name>A0A9Q8P475_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756818.1">
        <property type="nucleotide sequence ID" value="XM_047901062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P475"/>
    <dbReference type="GeneID" id="71981792"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01914"/>
    <dbReference type="OMA" id="HHMLPGR"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="227"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="374" mass="39617" checksum="3AF2AA428FD47FAF" modified="2023-09-13" version="1">MASTADASVRAAENDANCAAAVDNSTKRGSHLLVAGCNAHHQLFGRDGDVRIFTNKIDSPAGSSTTVLFSGWSTTVLATGQVFSMGNQDYPPSCSAPLTFPGVQLRSSFGDHNGIVGCLDDQGRLYLVNEPQASDTHMPLVLKSEESSPLIGAIALAQNDRIALSFKQAPNGRLCHVVEFENVQSFKQWFEDPSAEQNYPPSHHMLPGRPKQLVANHGTFVLLMDGGEVYSWGDARYQTLARPVTGEGSTPADKPGAVEALGGLHIDKIASGGWLGAALSRDGALYIWGNTTPGSTEPLHALESASESGVALVELPSGDGEAPDVLDMAVGDNHIAVIAEDHQVYVTGDNRHGQLGLASAQSWLPSWEARKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4U7</accession>
    <name>A0A9Q8P4U7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757821.1">
        <property type="nucleotide sequence ID" value="XM_047901741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4U7"/>
    <dbReference type="GeneID" id="71982471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02593"/>
    <dbReference type="OrthoDB" id="3257981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040153386" evidence="2">
        <location>
            <begin position="21"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="60106" checksum="FCB25AF106CB250D" modified="2023-09-13" version="1">MKWLSIMAAAVLLGVAHVDAKAVVAHFMMSNCYSYTTTEWQLDIQAAQEARIDGFALNVASNPDSTTDQQLANAFSVASSMGFKLFFSFDYAGNGAWAQDRVISYMNKYKSSSAYMQYNGKPIATTFEGTHQANDWNNIKTQTGCFFMPDWASIGASTAASAGGGVADGLFSWEAWPNGPTNMNTNGDNGYISALKGKPYMMAVSPWFFTNVPNYGKNWLWRGDDLWFDRWSQVLSLQPEFVQIISWNDWPESHYIGPLRPKEMGAFTYGKAPYNYADNMPHDGWRALLPYWIDTYKSGSTSLKNETVSFWYRLSPKSACGTGGTSGNDAGHNQQTYAPGDIVQDSVFFDAYLSSVADAVVTIGGLATTATWSTKPSGGSGVYHGSVPFSGRTGAVSIKIVRSGTTVVQQTGRDISTSCQNGVTNWNAWVGSAVGSIVAVNTTSSTSATSSSSAASSSVATSSTVSSTTSSSVATSSAATSSTGTRSSTTTTTSPSASTTSSVVPSTITQQMVFTVTQNVVCVCAPDCKCSPAGAAASSTAAAVSSSTSIAGTTSSTARSSTTSASSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4V0</accession>
    <name>A0A9Q8P4V0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02834</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757714.1">
        <property type="nucleotide sequence ID" value="XM_047901982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4V0"/>
    <dbReference type="GeneID" id="71982712"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02834"/>
    <dbReference type="OMA" id="CEREGND"/>
    <dbReference type="OrthoDB" id="2020758at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="132"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="551"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="631" mass="69294" checksum="84BEBBDFE1D2A466" modified="2023-09-13" version="1">MDPRIQLERLPPSLDTASTIACGILFLFGLHFTLQYLDYQILSPLEMLWNALVYIIPTPLLLDSARRQELRRNDMLSQTHAAKGDALRRMLGIGGNAILQRLPGVEGGGIVRRMSSAVTGGFAAPVTSDVPPGLGNWDNSCYQNSVLQALSSLGSLRSWLRVSEPGIGESGSTTNASLQETIAKLRDPSNNGKHIWTPAKLKSMSSWQQQDAQEYFSKIMDELDKEAAKNVAATETEPGLETVVREQDSGAEAETNTHTPGLPRNPLEGLVAQRVACTKCGFSEGYSMIPFNCLTVPLGSNNTYDLEACLDEYTKSEDIEGVECRSCTLISAAAKLKQLQLPVELRGQIAERLQAIEQALDSDDFSDKTLKQDCHILPKAFVNSTKTKELVLGRAPQSLVVHINRSVFDPMTGSQRKNYANVRFPFVLDLQEWMLSIGDASSHYQLSAVVTHYGRHENGHYICYRRHASLETADEHEDLGHDKRKESWWRLSDEDVSPVTETEVLDQGGVFMLFYERITEPGLPHATISSAPAEVVEEAAAIPLPADGADDWDLYPGKPSSTATPSLVTSSEHSVVSESDTDTDYDDEDPTVAKQSSQPTPVLKTASPTSLRPTQKDMKHAIGMSNTMMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4V1</accession>
    <name>A0A9Q8P4V1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxamine 5'-phosphate oxidase family protein ustO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757610.1">
        <property type="nucleotide sequence ID" value="XM_047902756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4V1"/>
    <dbReference type="GeneID" id="71983486"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="279" mass="31531" checksum="E0C4BEA6CE3A97D7" modified="2023-09-13" version="1">MGAFYEDIPDNIYEWILKQRMIWVATAPLSAKGHVNVSPKGGEYFGLVDKSTFWYMDLSGSGCETISHLRENGRITIMLNAFDGAPRIVRLWGHGRVLERHSAAFDKFVAEQSIQTIDATRSIIIVDVHQVGSSCGFSVPFFEFKDYRKTLNQVFEKKKESFESGKSMESPDRYWAYKNAWSIDGLPAVQRGLDCATKENVEPIVKFVGPWAPAAPYGPKSFKLSAQLRHQLVMLKTTRVQLTSVLMMVLLAFVVGMAVAIYGPMFVETQRRRFSTLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5A0</accession>
    <name>A0A9Q8P5A0_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_03314</name>
    </gene>
    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5A0"/>
    <dbReference type="GeneID" id="71983192"/>
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    <dbReference type="OrthoDB" id="4188028at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="642"/>
        </location>
    </feature>
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        <location>
            <begin position="654"/>
            <end position="934"/>
        </location>
    </feature>
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        <location>
            <begin position="981"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
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        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
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        <location>
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            <end position="107"/>
        </location>
    </feature>
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            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
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        </location>
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            <end position="614"/>
        </location>
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        </location>
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        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1123" mass="123231" checksum="CA21D0E11E70C404" modified="2023-09-13" version="1">MSPHSQTSTTTGQRRSSGKPGRFDPSMPLHMTTRRAAQKLPSQGSDSFDGSIDESESRRGSFNDIRPTTSHSLGSQTPAASRRVSGSSTHDASEINVSFESQSSPSKKSGRFRSDPFSPTVAATSPSRKRKRTTPTPPGTPSGSGDGEMLTGNDVADRHPLDVVEVIPMDQLSDREESRESSPSDDELAADYGGIAQSTELTPAATPLGSQPVSPISETSMQDIVFPAKVVEPVTAKVTKAAAIVEEAEDLDDAEDLAEADEIEEGDDVDEDHATLGPRRRIAGRRRADHPDARVEATLRRQLHIKSAFRAITRSLKPILAEIALKTTEQLDADPHLHEQVPEYQGTEECDGVQKQLDDILARRKAQIEAQYKWNKQNLRKTLEGETSARTATTEQKVNDLREIHLDRLGYDMLTIARKAQMSTRELGDETDDEDDNVIRARQGMQYRFVRTGPLGPEYESGSRMALEGERSIQDLESRFKMFEAVRNYRKADEQTRIPAGFTVMNDTARRAATARKESIQNTQVLADAATEQERLDNLPVIPVIPNEQAHDLQLLAKLATRPAVQPFPQSFWYNKPPQHSLGPPFQPQRMGPPQTPLRPPISFDQPQSQTSLRATFAHEVAERTPTRPSESPRHKAEPSRGDLAFLLSLPTGTYQKEEPSPRGPVKPAEPALSSHESVPPSPGAGSFQHTTESVQLTPSRLDREEESLQSNTNSRGDLSSEQYHRPSTLDRSPRFTQPVERPVHHFSSGPLSIARVDTTETKDDAGTEVHSKEQKREDLARHPSLPPKPPAPVRVPFDPPSIPGASDSRIGRDQAEVLSPRKASIDELLQRPRSRASSDVSQSTTTEATADSSTVGDAERGQSRNQGSKAMHKTSRTDRLGLSRKAFKQGKQNAGRRRSNNAEPPEGKPQIMRFRLNGPPETSAPPRPNITSTPTAALSQVANHEHYHPLSYGGFPIFPGHTIPPPPSLRRDPYPYPGSYEWGGHHRRSLQGPLPPAPGYEPSHTPPYGMPPGLPPMLPTGVPSGAGDWHLFGHPPFRHVSQPSTPHQGQHPGPGPLGQFGGPAIAPASDHRSSYGSGPSAGIPAFAQQKRQEEGSSRRRAQSDYAKRDFKHYDPTTKAQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Q4</accession>
    <name>A0A9Q8P6Q4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759443.1">
        <property type="nucleotide sequence ID" value="XM_047907705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Q4"/>
    <dbReference type="GeneID" id="71988435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08557"/>
    <dbReference type="OMA" id="CSIETMN"/>
    <dbReference type="OrthoDB" id="3650839at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="104"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="338" mass="37614" checksum="844FEF8E07750212" modified="2023-09-13" version="1">MDKQITSQTKDSWRQRWFSNATKKRARAEYHDDFGAYLAAFKPEPNVKPRTPDKEIRRQQRVLARAPHRALRESYYDTAEAMMKDLVTSLSSGRPTLSAAADIVFVCIDLEGDMQCGISELGVATLDTRDLFKSMKSASQCSIETMNYRLSKRSNRKFMHGQTTDLSADLLKSTILDSLVIQDDQNPSQNRNIILVGHSVRSELASFDGLGIPLEDLPSKSVLDTYALRQQIFGHSGALHEILEHLHVPHVKTLLHCAGNDAHHTLQALAAMLAIQLRARTAESGSGSVLAQLEGLAKKPVILPLAAEKREQEDWEDFLGEGSGLDWGEDGDVDGSWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Z9</accession>
    <name>A0A9Q8P6Z9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein klf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07915</name>
    </gene>
    <organism evidence="10 11">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759920.1">
        <property type="nucleotide sequence ID" value="XM_047907063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Z9"/>
    <dbReference type="GeneID" id="71987793"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07915"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="829"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="829"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1078" mass="119785" checksum="E30F68AE4BE09FE8" modified="2023-09-13" version="1">MIMSGVPGSKAMNKAAEQRPGSSNDGTVDDAEHEVDDVSENKPKKKRRIIKTTDKKYECPTKGCGKSYSRAEHLYRHQLNHTPKRHYNCDFPGCDRYFVRADLCARHRERHTAKGSHLQRKDAFMNSQRTAAANSDGTSPEFGLKASAAASIVSPVDSAHPRQQQSSSQAGTYLPPTAQQVQPYRPNGEQHHDQVPMPSLPPLQTEPGVGAQLNGAPYSAYQNRYPGSGQMMPPPTSPATTRRYSMDGQQERPVSMQNGYGQVQQQQQLPLHPPPMSSPAQGNQMYAQPSYPSTAGQPLVSAMNGGYTQLPSLPAFQLPQSYSGPGGPGPGTAMSPPAMSGASQYDIPPSSIGSMADFNNFDQFPSGYAMAVFGGDGFNHSPQPGMGDAHFIQQLFETGNFSMMEEPSPPGDQMVYQSQLPGAPLPKFEPPTVVDEQSSKPENWEENISPTINGMDLSMRECIVTEKKQARLIAMVRSFDDVERLPGRKCKEDILAGDTDDDNHPLSVNMLKTYITSYWLHTHQQMPIMHRPTFNPETCPDLLLLAMSCLGACCLERTHAAELIKNCAELAFFCAHHIRWEVFKDAEFRPTAKLWTFQTMLLLELFEKMYSTRDLHERAHIHHATTLTVMRRGSSLIGRAVIETPSGSGAAPAISGQDPTRTPPGPEGTVNTSGVNTPDAWWNRWITVEATKRVAFAAFIIDSTHATLFGHAAVMSPHDIRLQLPCDEALWSATSSAEVRRTEASLLANGIKPTMFMEGLKKCLAGQKVRTPNVFNRVILMAGLLNYCWQLSQRDESVKSLGVGTGNSKGWQSTLRAAFDHWRNDFDESLSSSTNDSNDYLPVSQSENKSRCHKDHRDNVFESNTCLHSLAHMAMHIAIVDCEMFAGAPRSLGREVTDADRAIVRRNMCERWAPSATARDAVFHALRFLCEVLLPQPEVDEEGNVKQNGMPPPLRFTYSARDDYLLNRPWILYYAVMIVWSYGYALDGPLTHSYNQLNTRESQILDMHHYLTRVGGVARPDDLESLRDRNSCLGLLILLRECFSQPRWELMHEAGDMLQRCIDHLLPQSGSNHSQVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P747</accession>
    <name>A0A9Q8P747_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase plo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07808</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759997.1">
        <property type="nucleotide sequence ID" value="XM_047906956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P747"/>
    <dbReference type="GeneID" id="71987686"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07808"/>
    <dbReference type="OMA" id="SPWIDFY"/>
    <dbReference type="OrthoDB" id="408964at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13118">
        <property type="entry name" value="POLO_box_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033701">
        <property type="entry name" value="POLO_box_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000959">
        <property type="entry name" value="POLO_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00659">
        <property type="entry name" value="POLO_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82615">
        <property type="entry name" value="Polo-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="384"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="999" mass="109927" checksum="A22F98A6B242CCCD" modified="2023-09-13" version="1">MSSSSIHADPPPPIVTEPSGINYATGSALGKGGFAICHKAERYDGSRPTGQIVALKIVKTKMEPAKLAQKFVTELQIHSKLSHPNIVTFYRAFSFQTSTYVVLEICPNGSLADMLKKRRHLTLPEIRRLVIQVCGAVKYLHHRHIVHRDLKTGNLFLDKDMNVKVGDFGLAALLVTEKEMEVRRRTTMCGTPNYLAPEILEKGKGHDEKVDLWAIGVIAYTLAVGKAPFHASTKDEIYKKLKSGTYTWPELNATSNQSADLRDLVSSLLVPEEQRPIPDKIVTHQFFRIAYVPASIPVTAKEKTPVWPEVAVPSAETIRRGYSETWYSLCKESGVGEPEQDKPFPLNGGRRVRSIVYDMTKEAQQGRTPTMPIPSDVVYTSTVSDFNSSRSSSPEEPDLAQSTRGLKEISHNEVAASRGRLARTDSTKAAREAEMMPPPRAPSRVARSNTVRKAARTISEEAAKSSESVKVASDPAAAASSSQTLKVTRVRPAHTRTESASAATKALKETNASTTTTYRTARTEQPSSEGSDPEKPQRSGTVKRSADASLARRPRGTRTMKERPTSPVDVLAAPTQPIAARLAKDRAQSPPEVTGPLATLDDLKQALPTRHRKQPSKAEVIEILSDPEPEDKIETNNLHLSRPPPMAKRLPVPQKSVSPEINPAIPGSDPSTVLEKLTVLRDNLASALNKPTSTRRPSLQRDIEAASNLPFVSRWVDYSRKHGIGYVLSDGTVGCIINATSKPNQPPTPVSHVLVRNGQKWLQRVSTKSKDFAGIEQVPLEFFEDRGDEGIERKIYKGLGSVNGDSERKRTLSVLWVKFGRYMCQSLDGEENEGSTKGENFVRFYQRIGSVGVWAFADGCLQVHFPDHTKLVLSADGKIISSTLLTVEATQHLNSSGELLPQHVNSRQVFADSIESLLFSSNRIRQRTVKANQLSDKLKFVLEVVDQWVSGSGLGHLDEDEGAERLYWEGLCVRDQNQRKVDRVTVGRFGGDAVPSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P796</accession>
    <name>A0A9Q8P796_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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            <begin position="266"/>
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            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15662.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <sequence length="336" mass="35466" checksum="3F8152128E49FDD6" modified="2023-09-13" version="1">MLRVVLAAAAAASVVLAVPQGINFQAVNEAPTPTPTAQGPPIAAVKEVPTYKPAAAAQEAAADAAADPVTAEKRSLFARAACDRQPQGAGPVTSPDTAQDFLANKQYSDIANGAATPQGYSLVFQDLQGATQQNGYLGFYTLNSYDTIKCQQLCDSTATCTAFNTYIERDPSLEPGADCPNPPSTVNYKCSLYGLPVSNTTATNTGQWRADFQVVITGSNGYLKNAPPPSYPGFSGPEALGGAIDVPVAEGNGSYLGVKIYPGPYDPGQCVGACQATTDCNFFNSYILSKNNSPVGTYCSFYDRAWDRSYATNFGQYDQEGNYYSVSSSYSYTLTN</sequence>
</entry>
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        </citation>
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        </location>
    </feature>
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            <begin position="1"/>
            <end position="11"/>
        </location>
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    </feature>
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            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
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            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="18530" checksum="173B530240B55BDC" modified="2023-09-13" version="1">MAKNTALHDLEPFNLILYQPNEPEPDDDYARDGPIVARRTHWIDSPERPRPPPPKRTHDQLNPTSPARRPQRLRRDGAERRPASAPATQAGRLAIPDAPLRQTQTYDQEAAEGAVTSEDETMDDDIAPIHEGSTRGQRTQEQDTMVQNMSERACAAAVRRRLPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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            <begin position="4"/>
            <end position="514"/>
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        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
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</entry>
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    <accession>A0A9Q8P894</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    <dbReference type="GeneID" id="71984025"/>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="38554" checksum="3470B7B7EC1DA43D" modified="2023-09-13" version="1">MIHYFNEDDIAVLQAAWNYIQAQANIKAANAGAQVDLTKERQDLCNVESLAKEVKHRNVVQQQPQHRHARWLRSGQGWRLFEHHVLEVTATAIASFTGPQCTKDQSMALAAWPSWFSSWKGPEAGVAPIMQAIEIFNHLFFLGKLQNMHFLWREGLRARGDALTSGPGTDGYTQRVSNQQILIVMDPEPDFTFDRTWQDDLLSTLLHECCHAFIDLYRCHKHEGHHACRNEGKTGHGAAWFHLASEVKVAARSHLRLDAELGVLTSVVGECRCNPSISASDWEHFEMRFSAQDKDRMVRQMKRKRSNPDELLTIYQQDSRACDSIRRILDPRKGWNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8J5</accession>
    <name>A0A9Q8P8J5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761332.1">
        <property type="nucleotide sequence ID" value="XM_047904423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8J5"/>
    <dbReference type="GeneID" id="71985153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05275"/>
    <dbReference type="OrthoDB" id="3838727at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040451094" evidence="1">
        <location>
            <begin position="18"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="20599" checksum="A0BA48C5C4C0C59A" modified="2023-09-13" version="1">MYTPGLALTMLTAFAAAAPQPLSTRGGDAETFKLHVYNNCSFPKSVAIYQITSDFQMLEKSKPTSLKAKTGKTVIEAPYKALGMRLSGHAEWGTAGQWKTQALFEFGYGEYMGAKGTAYNLSVMEGSDADIGIGGYPIANGKGSGTCTSKTCFPWDCPLDQGWTNPDQTEDGSPADTVCYHGKTDFKVVFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAP4</accession>
    <name>A0A9Q8PAP4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S10, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial ribosomal small subunit protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06849</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763376.1">
        <property type="nucleotide sequence ID" value="XM_047905997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAP4"/>
    <dbReference type="GeneID" id="71986727"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06849"/>
    <dbReference type="OrthoDB" id="366214at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000003">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="8">
        <location>
            <begin position="111"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="293" mass="32770" checksum="54979B041B88592A" modified="2023-09-13" version="1">MLVKKALFQDLSSTIAFHSHTIQLHTHTMAPPSCTRSFVGAVKRLKLSPATPAAQHQIRHIQNSSRNAASTIQSSSTDGDASNIRLPKAVQATYLAPLKRAPSQNPTKVADLQLRSYSVRNLEVFADFAMRAAYFLNLPAAGPTPLRKITERWTVPRSNFVHKKSQENFERITMRRWIQVFDGHPDTVAVWLAFLRKHQYYGVGMKAEVYEHGSLTTGARLESEAEKVRVLIGKGETFASFRGGLTGRAKRAEQRLWDSPFKRSWGADAAMGGTPSTGTSKDRLWVPRQDRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBL0</accession>
    <name>A0A9Q8PBL0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-rRNA-processing protein RIX1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RIX1/PELP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763839.1">
        <property type="nucleotide sequence ID" value="XM_047906813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBL0"/>
    <dbReference type="GeneID" id="71987543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07665"/>
    <dbReference type="OMA" id="GGWEILR"/>
    <dbReference type="OrthoDB" id="20900at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012583">
        <property type="entry name" value="RIX1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105:SF1">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08167">
        <property type="entry name" value="RIX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein RIX1 N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="593"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="733"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="602"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="745"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="771" mass="83385" checksum="040F9B9485092B8F" modified="2023-09-13" version="1">MGHTAASAGALEALTYRVSSAPVDELPKIAPQIAGAIWNCRQLLSAPAETKRTAEDTNAIKQFNTQLTTLLQDRTVEGRWSAVVLAKATIEAAGLEVLSKCNPWVRSLLGMLKKPDPPTTRSLIVLTLTSIFTLTWDYSNIVREITTPALTAFVPTCLANIENRRCSATELQTVLEAFITLLPRHPTIFRTNEAKIRSFLANILSSGSTNVAFHHTQSHQTSARRLLVALHHCAPKQGAAEKWEETLRTAVTAVHTTCDRVLRTFQEDWQSVAGIEPSVPAHLTLKGANAELQSLDVDAAGLKPWKGVYAGCDRIITLLHTIGSHIREGTAGSVATPVGLVIDLLTRLFSVTVPRPGKQDFVKLNNEIAKEERDALFAALPDVHAAAVKLCITLLDRFGKQALPLTQNIVDQALWLFKAEHQYDSLRFPLHQLFNTALQLLGPAMSKEDTSELMPVLKACCKELMPDNGSSSSSATTSAASGIKQQLGLTDSGSSHSHPTNLAPLKQAAESLLETSLIKLDAACMPPQVRAQIDRTAVLIRSQKMLVASVMNPVVGTKTARGQASLMPILAREFSHVSEVEALLRPRMPFIHSGRKKSRMGDEDEEELANSEHDDGDSEDEDEDEDGQGDDEGDDQKEANHVEFGAQATTGSVPDSASKGKRAATDDTDLATSAKRARASPAADVLPSHDARSEQAQLPEIPILEAPASHDIAMEETTMTVVLPTEDSNTITVAGSSRHAISDDNAMDDSDGSDFEMPELNPDPDTDPEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM0</accession>
    <name>A0A9Q8PBM0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spindle pole body-associated protein cut12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763857.1">
        <property type="nucleotide sequence ID" value="XM_047905966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBM0"/>
    <dbReference type="GeneID" id="71986696"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06818"/>
    <dbReference type="OMA" id="KFPSPWS"/>
    <dbReference type="OrthoDB" id="5383703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021589">
        <property type="entry name" value="Cut12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11500">
        <property type="entry name" value="Cut12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle pole body-associated protein cut12" evidence="2">
        <location>
            <begin position="171"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="67397" checksum="3ACB0731206A502C" modified="2023-09-13" version="1">MLHWLAGQKPHDGNADPDATGFIEPPETPAPVFAVRAFKHAIFGTPGTVQKPPRRHSEDETARRKHNARPGMLRPKSATETATLNRYEPAIEDEPLPSPTKGILLTPGTAAARRKTVSFGDNVVDNENKKPMKSVSGLPDDCPGKFPSPWSKSVIEQDTTEQSAEKLGGRSKLTEQLQQVRDESARRKAKSSRQARDRDEQDETLDLAEPVSQSGKYWQQEYNIYRERTTKEVRKLVEKTKSSRDYARKVDDENLQLKEDLRQETSKVAKLEERVLELEAQLKDLHAKMQDRGTVRPSVKDESRPARGISGLLSDNRKIVAPKPGEASDEQAEKADSHRLSWKSGLAQRSRDRAQSSTTTAAHEEKFEEAKPADQKPSNKLRSRPRDIKVNPRDDIWAPSSGLGPPPPEPSPPSPRASRAVTSGTDATCLKSLSINTLPRDDSRALAMSMGLQPPSPEREKRQDTPMRSPGLPQPSPDQPGKASTRPQPEPAKLSYENDASIRVPDKSSLFNPDTILERPNVLTGTPVPLKPLPARPTLQTRRSPDAKENVAPSRRPAAHNMENDKPTAAWNNLDNSKRITSRDGKEIPADKLAAARERLLAKGRNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBN3</accession>
    <name>A0A9Q8PBN3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763885.1">
        <property type="nucleotide sequence ID" value="XM_047906836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBN3"/>
    <dbReference type="GeneID" id="71987566"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07688"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="322" mass="35434" checksum="F0DE8EC92919CB7E" modified="2023-09-13" version="1">MDVFEYYEAAMAKQFTPMLFVKAPEGLPTVLLVGGGKYQVPHDTRVVLGPSVDRDWRQVGLPGGTFVYAAKLDHLEKQCSTTAEGARLFQDVAGSEDRSAATFIPYSRHVMGMSLRCYTMAGDTVTIPQGDFVTCGVTPNLLDSDVNIIKAVVNTRVHYVPFSQSVLRNMLESSTIILADGRPRTIVAQAIQDHPPAAQFVHIPPVTIVNDLVGCGANCQKVQVHAGEVVDWLFVDYAGLRYCRKRSTGEMYVFAYLTRDVQDRVEAIYDGIAFRGSMEADVDAALERFIVANDHPLFHGQNECDSCHHFFGVHQPGCANAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC21</accession>
    <name>A0A9Q8PC21_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Catechol 1,2-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10286</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764150.1">
        <property type="nucleotide sequence ID" value="XM_047909434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC21"/>
    <dbReference type="GeneID" id="71990164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10286"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="4">
        <location>
            <begin position="2"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="82" mass="9434" checksum="D960A63F868AA8CF" modified="2023-09-13" version="1">MDRHPYRPGHIHLIVLKEGYEPITTQIFDAKSDYLDNDSVFAVKDSLTVEFQARKNDPEAKLEIQYDVRMAPSDPTKKKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCE4</accession>
    <name>A0A9Q8PCE4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Oxidoreductase ptaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09851</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764330.1">
        <property type="nucleotide sequence ID" value="XM_047908999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCE4"/>
    <dbReference type="GeneID" id="71989729"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09851"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000038">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040452374" evidence="8">
        <location>
            <begin position="22"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="90"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="214"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="446"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="620" mass="68805" checksum="E1A689FDA2E0A770" modified="2023-09-13" version="1">MAGLLSLLLGATKLIPGLSQGFTNGQSQWGTIGQPSLPPYLGNNPGYEVSPVQPSYPGPAPGQPPQGPNGGPPPVMPDTGEVRRYDWTVHRQVMAPDGVVKEGIFVNGQYPGPLLEANWGDWIEVTVRNGLEDEGTTIHWHGLLQKETPWYDGVPGASQCPIAPGKTFTYRFRADSFGTSWWHAHYSAQYSDGVFGPMIIYGPNHVKYDIDVGPVMINDYYHDTYVENLKESLGQRVTPRSDNNLINGKMNFDCSQATNGQKCTPNAGVSKFKFKSGKKHRLRLINSGAEGIQRFTIDEHKMTVIANDFVPVKPYQVSWVTLGVGQRTDIIVEGTGKSNGVYWMRTEISQFCSFPNQPYALAAIYYERASTNAVPQSKATPVQDNDCSNDALDLTEPFYQYDRPSEPSITTRIDMTNIQNATGQFVWVMNNSSFRADWDSPILLSAAQGKSQFPTQQNVYRYSRVNERQTIRLILHSIAAPLPHPIHLHGHDFWVLAEGYGEWDGSIVRPSNPQRRDVHLMDKALPPTGGTVATSGGPPGTPYFIVIELEADNPGVWPMHCHIAWHLSGGMYINVLVSFDERPEDIQRERQTIESVAAQTCPDWKAYSSRNNVPQIDAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCK4</accession>
    <name>A0A9Q8PCK4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCK4"/>
    <dbReference type="GeneID" id="71990023"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10145"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="122" mass="13636" checksum="6DA930513A4F2BA2" modified="2023-09-13" version="1">MLSPVFCRVYNSSHLKRLGDKHSREHSSEDARTSFHTLITMAAEHSQREVFSSSHYCHSSPVVLHPSKPDPTSIRMDFNEWNELEGGYSPALTKSDSHLEQPQSPITEIAITTNGQTITAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCQ4</accession>
    <name>A0A9Q8PCQ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764487.1">
        <property type="nucleotide sequence ID" value="XM_047909835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCQ4"/>
    <dbReference type="GeneID" id="71990565"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10687"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="142" mass="15740" checksum="6BCFAE41A88821D0" modified="2023-09-13" version="1">MDRSGNNQHGQHLAGAGPAPDATATPIAHRIDHDGPDSAWDNVNLFRDLCWGELFDGLIHLDDICGTFILGLIPIITHGDLKDNNNALCARIPGAAPIKDSGVTDRWEDALRHACPNNVEYEEEHKRICKARRATYDKPRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCS8</accession>
    <name>A0A9Q8PCS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U2 snRNP-associated SURP motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764449.1">
        <property type="nucleotide sequence ID" value="XM_047909430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCS8"/>
    <dbReference type="GeneID" id="71990160"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10282"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="474"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="709"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="727"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="820" mass="90164" checksum="7E2301FF07A6B55F" modified="2023-09-13" version="1">MADEERAAPAEFPDVREKLAAPKKLSAFEKERLAAQEKKRREAAENEKALREFQDSLGGDEEDEDAFDGFPRFNKPPAAPQGGFGGLPSRYGASGPRSGPGCLGPVAGVVPPNLKRKRALDEMREAQEARREQEDLAAFASRNAARPAQDSRDTRDRDEEMEQEVAPRPTVQLSSLPPMTREEDVKALLGPYLQVHSVRLQPPPRTEYGAKRSLTAIAELSSETSTTHIDAAVSALKDKYLSAGFYLSISRHLLSTSWHGNLPSVPAATSAEPFGAQKVNKDQPARFNMRNAPPPSDFAPPDSYDAPARPAISANATIHVQPPVDIATLRAAHTIVDRLLSEPDASRALEIEAMLMSLPEVQDDERFAFLYNSRSTAGVYYRFLLWGDGDGYDSIQARKRAAQGPERILDDVIIDWVPPHEEVPFADLSSLGEVIDHSNYESSEEDSDDEERRHFNQSGREGQGPPPPTERKHLTPLQVAKFAWLLSRMPSSHTKLRKAEVGAVTSFAINNAGAGAEEIVDMLVLNVEKPFTSTQCARFEKEDVNQDEDDMYEPDEELPTLETTSAPDAGKTGEEKDDPSLAKLVALYLINDVLHNSSTAGVRNAWKYRQLFENAFKRQKTFEHLGQLEKDLGWGRFRAEQWRGRIRGLFEVWEKGSVFASDVFEQLKKNFFEQPVQQDEEAEKAAADSKKLEEKRMARFKRVDGTGTPADSESPAPAAASSNVDGEPLEDLDGAPMDDLDGIPMDDLDGAPLEDLDGLPASDARMTDAPPAKANPSTAPQAQDTKGGISLKSSSGAKPPATGPKRRKLAEDMFADSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE72</accession>
    <name>A0A9Q8PE72_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Replication factor A protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11041</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765305.1">
        <property type="nucleotide sequence ID" value="XM_047910189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE72"/>
    <dbReference type="GeneID" id="71990919"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11041"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="8">
        <location>
            <begin position="73"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="9">
        <location>
            <begin position="170"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" evidence="6">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" evidence="6">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR036949-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO20939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="29971" checksum="76F2CA1F8FC860F6" modified="2023-09-13" version="1">MDYGYSTTSYGAQGGANGGGFMPGSQGEGSATKKNSYGKDTLRPVTIKQLIDAHHPHPGADHFVIDESECTQVTFVGQIRNISTQTTNVTYKLDDGTGTIEVKLWIDAEAIENPDDPRNQKPKPEEQGYARVWGRLKAFNNKRHVGANIIRPVQDYNEISYHLLEATAVHLHFTKGPLEALQANGGAAAAAQQNGYGAQQQMTNGGDSGLAGITPVARRVYQCLKTSPQTNEGLHAQDIATRTGMEMTEVLKAGDELMGLGKVYTTVDDHTWALLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEG1</accession>
    <name>A0A9Q8PEG1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765321.1">
        <property type="nucleotide sequence ID" value="XM_047910530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEG1"/>
    <dbReference type="GeneID" id="71991260"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11382"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="59" mass="6387" checksum="A0459C1C0DF17896" modified="2023-09-13" version="1">MPSEGKNIFFLTVAGIGAAAALFGTTRRFTPRANPKQFEKQHNGTPTEPEVDPKDITGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG69</accession>
    <name>A0A9Q8PG69_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tyrosinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09414</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766272.1">
        <property type="nucleotide sequence ID" value="XM_047908562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG69"/>
    <dbReference type="GeneID" id="71989292"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09414"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041640">
        <property type="entry name" value="Tyrosinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF32">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18132">
        <property type="entry name" value="Tyrosinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040286909" evidence="5">
        <location>
            <begin position="22"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="7">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="632" mass="69970" checksum="3F2AD9D9298F2AC0" modified="2023-09-13" version="1">MHIHSLTAHAALLLQLGLAIGTPLLQHQVEELSSTSASSYSQHERRQSSNGTFVVTGVAGAGVHPRLELRAMQDDADLWNLYILGLRRFYDTDQDDKLSFYQISGIHGRPYGDWDGVPPAEDTDSPGYCLHVSNLFLTWHRPYLALYEQLIYEHVIDAANSFPAGAVRRRYLAAAGRFRVPYWDWAAVPPNGESVWPTVVTTPTIGVTLPNGTANISNPLYAYNFHPNLLEDQVIDMFWDPFTQWDESKRYPTQPLTTLSESQNNLIGSVLDNLRNNLMNRLYNQFTYYDNFTLFSTSAWIENGIQNADSAESIHDVIHNNVGQGGSMTYLEFSAYDPIFWLHHTMMDRILALWQELHPESYVQPRVTGMGSYTIPVGMTADANTPLAPFHKSSNGDMYTSNDVRSTTTFGYTYPELANNASTASVRVAMNTLYGSNAAAGGPVRRAQPISSAASRKQVETTPGEVIDGQYRHYVANIVSSRFAVNGSYSVYVFLGDPGEEEPSNWQLSHNLVGSHSVFAALTKAGARMKTAGMNPIKVTGAIPLTDSLLNKAAAGEVKSMDSETVERYLRRSLQWRVAKMDGTILDAANVSDLSITIVSARVNPAVNDDDFPSWSDFRELKAVTEGKVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGH4</accession>
    <name>A0A9Q8PGH4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cercosporin MFS transporter CTB4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cercosporin toxin biosynthesis cluster protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_08937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin. The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules. These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids. Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766437.1">
        <property type="nucleotide sequence ID" value="XM_047908085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGH4"/>
    <dbReference type="GeneID" id="71988815"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08937"/>
    <dbReference type="OMA" id="AMCACPL"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="77"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="515" mass="56384" checksum="29CA145DA0F2C775" modified="2023-09-13" version="1">MAEERKTYTPSPAASEHTIDGDIEAQRSITNEKTTTVNNTKPNNHNEPPQHPNTIDWNGPNDPSNPRNWTTKAKIANTALVIVLCLLTPLASSMFAPGVPQVLRDFETSAATIAELVVSIYILGFAIGPLLISPLSEIYGRWPVYIVCNIMFLIFTIACAVASSIEQLIVFRLFAGIFGVCPVTLGGATISDLIEQEKRGLSMSLFGMGPLLGPVIGPVAGSYLAAAEGWRWTFWVIAIAYGVASVAHFFLCKETYGPVLLERKTARLRKETGNASLMSALDSGLERKERILRALVRPFKMLFLSPIVAMMAIYAAFVYGILYLLYTTFTFVFMEYYGFRASNVGLTYIASGIGMFMGLFLIGGASDKLLKSKAAKHGGELKPEYRLLPLMYTGWLCPVGLFIYGWTAEYHEQWAVPLFGTLLFGVGIISALICIQQYLIDAYTVYAASAIAANTVLRSIVGGLLPLAGLSLYRELGLGWGNSLIAFIALALTPVPFVFYIFGERIRKRDGGLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGK0</accession>
    <name>A0A9Q8PGK0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09671</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766449.1">
        <property type="nucleotide sequence ID" value="XM_047908819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGK0"/>
    <dbReference type="GeneID" id="71989549"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09671"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000007">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="11">
        <location>
            <begin position="88"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="10">
        <location>
            <begin position="275"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="581"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="588"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="622" mass="68740" checksum="3CFB02977521CF0A" modified="2023-09-13" version="1">MTQIKGSQAPAANIKRAAQHHHHPERRHVPAPADYDTSNPIETRKYLHTYGLTPPGVDTFETQSGRCKAILASRKTPIEKYQYLSVLRNTNVNLFYRLLAENVKEFTPLIYTPTVGEACQTWSELYTQPEGMYLSFADKGHLHSVIQNWPHEVEITVVTDGSRILGLGDLGINGMGIPVGKLSLYTACAGIHPMRTLPLCLDLGTSNEELRNDPLYLGSRRPKVTAEEEKEFLDEMMAALTERWPSIVIQFEDFKNPFPSLERYQDTYTMFNDDIQGTGAVITGGFINAVKQSGVAPKDQRAVFLGAGSAGVGVAKQLTEFFMKEGLSEEEAKKRFWLVDSQGLVTLDRGKLAEHKLYFARDDNNGQQFKTLPEVVEYVKPTILMGLSTIGGAFTPEILTRMAELNDRPVIFPLSNPSSKSECTFEEAIKYTNGKCLFASGSPFPTLEWEGKELVPGQGNNMYVFPGIGLGAILSKSVNVTQNMIYASAEALSTSLLPSEIEDNWLYPAINRIRDVSVVVTRGVIRAAQKDGMDRELALRNISDEELDDYIRERMYDPFTEHKKVDEEIKELAAEFQRNVIGSGSGSNGAATTVGGAEAEAVANGPPRGEQTHGDAMTVQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGS1</accession>
    <name>A0A9Q8PGS1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_09141</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766700.1">
        <property type="nucleotide sequence ID" value="XM_047908289.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71989019"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09141"/>
    <dbReference type="OMA" id="QLPGYTW"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000003">
        <property type="entry name" value="Histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000285">
        <property type="entry name" value="Putative sensor histidine kinase/response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000579">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF46">
        <property type="entry name" value="HISTIDINE KINASE_RESPONSE REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="41"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="1865"/>
            <end position="2087"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="18">
        <location>
            <begin position="2138"/>
            <end position="2261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="445"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2286"/>
            <end position="2312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2326"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1821"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="2328"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="13">
        <location>
            <position position="2192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO22334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2384" mass="266084" checksum="E2B889532A666D68" modified="2023-09-13" version="1">MGLDIEDEESAAPFKRFFERLREDVPGYEFNDRIPPFHSSYDNWHFFGRRKSRPNVSGQKTSASEASSSRPSSIRTRSDYDIPNDEEKEREVWVIGRMSKQILRLEREFKLCQTLFRQQTEGQKHFVRPLDFFRLPARDVDDVPLCVSVVEAPGRDYLNELVEFGPNFYMGTPESPQQHHHEQCALLTFLDFAIGASECLEILHHGNQIVHGEIRGDAFHYNKETGVVRMINFGSGVRSFEHGLTSANWSSLMQQRGIEHKLQFIAPEQTGRLPAEPDARCDIYSLGILSWSMLTGAAPFEGKTSLDIMQSVLSRRIPLASSIRPDVPEALAKVIRKMTARNMEDRYNSTSGIKHDLQELKRILMDGDQDALAEFKVASTDVSCFFTLPSQLVGREEQRKVIINVIEKAAAKSAKAASITRRGLYSISSNSSLISGEKDIVLDDIMSDSTSSTDRDRGRDDSRLMSIPEVPPYEPSKRSASQSRQDRMGSVASSATSTLGEPTDSRGSNDIAESLHRTTSSSFQFNGSPGEPGSLLRTAQKLKKKGKTEIIGIEGAAGFGKSSLVQNIQITARKHGYFTSAKFDQVRSAPFDPIVRVMSSLFRQIFSENDVGTAFHDNIRTFVKPFWGVLHASLELPLWLLEPATDGKTTNASNFMANPTLQNGTLGSMPERKACNAASTQEWLRSGGSAKSSRFMHIFLDVLRLLSMQKFVCFCLDDLQFADPESLELLQVIAGAHVPIVLMLTYRDETELTAPVKRLLSKAVKVSVGAFTDDDTTEYVSQTLHRSADYCTPLVAAVQEKTQGNPFFVREMLDSAYRKKCLYYCWKHSEWEYNLDRLFEEFASPDTGKFSSNDFILRRMKELPIDAQAVLSWAAILGNSFQFQTIKRVMSCACSDLAPQPLIPPKSTDAVAGLQVALQSFVIMPTEDEDRFKFSHDRYIAAADILCEAYVRSEMHYVVATSMMKHEPYDPVSQPNKVLFEQARHVCEGVEAIKRRAPKKTKYRELLYQAAETARESGARRSGLYFFEHCIDLLPEDPWDDDTDDASYSETLALKTRAAEAYWYAGEYNESSQLLEEVFDRARDTADKAPAAIVLSRMHAQRGDSQTAFNTLKAALSELGMSVPETTWDDCDEEFQSIIPMLQGNPPDYDIANTKSTDRHLTTLGALLTEFQSSAYWTHHLLYYQSTLLIMRLYLKYGLFPQAALGYVNLAALSVWRFSMVQAAVELGNTALKIIDTYSQELYVGGRTLTLYAVFLGHIQKDWRDNYELLNEGLECASSAGDKILHLLNIGIMAAYRLWASENLADTEALIASVSDEFPDWAENLRGGVFLVGVRSYARALSGKTYYKVASDVLTDSSHDSSAYERYIASTASSPDRPLSIYQSFRLIAMYRFGHYKEAMEFGTEMLQRTDGLLCQRFRYAALFYLSMSILACIKDEPDRSDRDELLQRVAKYRAHIEVISSVNDVNYVVYLQLLQAETADIEMRYGEVLGHFETAVNHSVLHSNILDEALSLELYADWLVRRGAARPARGILLDCVSAYRRVGAFGKAEHVSEKYGYLLFGTRSLATVDAGTQTSDAGAGPSYVDKLEKISTHEAAQTPADRTVEWLDPHAALRPRHDMLSKEMPAALSSAVGLDMIDLAGILESSQLLSSELNVDRLLAKLSNIIVDATGADMVGLVVENEGGEWCVASVGTPEGVDTPKADIPLMEVEDQVAKQVTLYVLRFKEQLFLRNVLDDERFSNVPEKWLEDNPEGASMISLPILHGEDVLLGSLYCQAPPQTFTDRTVTLLKLLVNQIAISIANALLFKRSEKVQASNTSMLEVQKQALAQARDAEKKAKEAEAKAMEMVRLKDEAAKAKSMFLANVSHELRTPLNGVIGMSEMLKSTPLNKEQEEHADSIRVCADTLLSVINDILDFSKLEAGKMQVFSVPLSLTETITEVVRALSYTNLERNLKTITKLDLDQNLVVMGDPVRLHQILMNLMSNAYKFTAKGSVTVRAKVDSEDADSINVTVSVTDTGIGVSEEQQKKLFLPFSQADSSTARSYGGTGLGLSICKAILENVMHGHIWLESAPGVGTTVSFSLPFKKVNKSELSESNGNTPHGRETDPMAMFSPPAIDDAPGARAIVSLQGIPRDQLKVCIAEDNPINQKIAINFVKKLGFNCEAYGDGQQAYDALERAAKDGHPFHLVLMDVQMPVLDGYNATREIRKSEEPKVRDILVIAMTASAIRGDREKCLEAGMNNYLAKPVRADTLKQMLESYLHQPARAMPNLQEEANNLVNTVVSEEDDKEENHIPRIHIQSPPDRPKSAQHRDTEIHLTPEEMARKPQAQANMQQQMQAAQQQIRELQEKPSRAAGGKKIRRPGMERTKSYYSATSAEGSEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHJ6</accession>
    <name>A0A9Q8PHJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767001.1">
        <property type="nucleotide sequence ID" value="XM_047911179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHJ6"/>
    <dbReference type="GeneID" id="71991909"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12031"/>
    <dbReference type="OMA" id="WAIAETT"/>
    <dbReference type="OrthoDB" id="10650406at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="39163" checksum="B80B27BA86B98F6C" modified="2023-09-13" version="1">MPPHKTAPGTGKHRQIHGDLHEALTKIVGKTLYLPEPMLTRVHVYATFARTLYQQLRSEDNEALDTIGYHVMAAYELLATAELADEEDEDVEDAVVNALQPSAPKKRGRDSKQTRAETVAASPKSGRGRARAAGTGSEHTKSYEDILEVFPKDKQRQPKKAPIVNDEDGQAEGDAPLWKALLKQKRRDRSKQVPALEEEGKNEAGAGDAIATVSQPKQKSRSGSKQAHLPPVQNKTVEADEAEDEDEAPLLVPAKPRGHVESASTPQQTQQPAKSTSTTRSSGRNKRKASNDIDADADAAPAAPKRSKRVRGGDLAIDGNQGMGGKQTRVPVTLYQAANQKWYEVPGATEWPGWAIAETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIB4</accession>
    <name>A0A9Q8PIB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bypass of stop codon protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12219</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767359.1">
        <property type="nucleotide sequence ID" value="XM_047911367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIB4"/>
    <dbReference type="GeneID" id="71992097"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12219"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF16">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="52"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="446" mass="47429" checksum="1F477D7155151F51" modified="2023-09-13" version="1">MPKHEGSMAAEPAGPPIELQPQDHVRSDDLEEGSAQHANTTSAIQPLVVRDVTALKPVSAILCFLNCGVNDGSLGALIPYILRHYTISTAWMAIPYGVAVVGWLLAAMVGGYIRISIGTGGIIVAGALLQLLAQLLRFWEPPFGLLSFTFFVVALGQALQEPQANTFVTSLKSTHRWLGVIHGCYAVGGLIGPLIASAIASNMQGQWAAFYYVPTGIGVVNLALCSYAFRDEVAIRRSHGPSANTRRSRTALVELKATIKQKNVWLLSIFSFLYLGAAITAGGWVVEFLVEVREGRLSQVGYIAAAFMGGTAADRFLLAEPAHRFGEKRMGIVCAVLSIVFQVIFWQVPNIVVNAVAVSFLGFLLGPFFATAVSVGSKVIPQELQQSGLAFMFLVAQAGGATFPAITGIISARNGVGTLQPVLVGLLAAMTVAWLVVPNPRGKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PII0</accession>
    <name>A0A9Q8PII0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11782</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767517.1">
        <property type="nucleotide sequence ID" value="XM_047910930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PII0"/>
    <dbReference type="GeneID" id="71991660"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11782"/>
    <dbReference type="OMA" id="AMLMTHI"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="50"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="470" mass="50386" checksum="166EEC7F360F5F91" modified="2023-09-13" version="1">MYEEKKVGEELAPVPTTDFGDVQDYPKTDATHDAVFGEINEDGPNYRDVGWMGTVILMMKTQIGLGVLGIPSALHTLGMVPGVIILIVVACMTTWSGYMVGKFKLLHPHVYGIDDAGAIFGGRIGREILWFGFVIYFLFLSASAMLGISIGFNALSVHGACTAIFVAVAAIIGMLFGSIRTLGKVSWIAWAGVGGILTAVFALTIAVGVQDRPSDAPQTGPYKSDSRFNVISDPTFEEAISAVATIVFAFAGSPAFFSIISEMRNPKDYTKSLIIAQAGVTLVYLVIGIVVYYYCGSYVASPALGSAGPLMKRVCYGIALPGLIASCMLFVHLPAKSIFMRVMRGSKHLTANTAVHWLTWLSCTGGVVIVAYLIGSGIPVFDGLISLIGALLATFMSFQPMGCMWLYDNYKRSVSERDAKWYGQFAWVVFIITAGTFVMIAGTYGAVVGIINSSDRTAPWSCADNSNSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJK6</accession>
    <name>A0A9Q8PJK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Structural maintenance of chromosomes protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_12737</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767920.1">
        <property type="nucleotide sequence ID" value="XM_047911885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJK6"/>
    <dbReference type="GeneID" id="71992615"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12737"/>
    <dbReference type="OMA" id="MCHDHFY"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="14">
        <location>
            <begin position="129"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="783"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1053"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="293"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="395"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="812"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="953"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1059"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO23554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1168" mass="132741" checksum="C36E408D4A287116" modified="2023-09-13" version="1">MAPMGKRRRDSSDNDEEEEIVIESASSSFRQNNPHKRTRVALARASTVGSVVSEDFEEPDHEHFDDLLEDPEEDGRVDANTDHSLFNQYSDLEQPEDDVDEFAATQIVKRQYNEHKENRAEESGIIHEISCRNFMCHTKLTITLGPLINFIIGHNGSGKSAILTALTMCLGGKTKATNRGTSLKGLIKEGTELATLCVTIRNEGENAYKKELYGKFVKVERHFSRSGTSGFKIKNEHDKIITTKKADLDDILDYFCLQLDNPIAVLSQDNARAFLSNSTAADKYKFFLKGSGLETLNADYALFEEQLDKMATQLNTRTGDIDNLKRVADQAEERKKRGQQVQTLISKRRKNEREMAWCQIEMAEQELATREERVAEGVEAVTKAEDDAQIATSAFENHEAARDAALRAKEEIQNRLGPVTDKLDLEREKFEKNKKELIEMKTEQRQIKESLKKAKEDKVRLAKDIDEENARMAAADGDAHTRRVQELEELKAAFEAAKAKLEEHNSTYEETRAAVAAAEQKLKATFKDKQNADQEVSKVQKRLDDMNRDEDNVYGSYPRGFDQLVREINRETRWRQKPVGPMGIHVRNTKPEWSSVIERTFGGVLNAFCVTCKDDQNFLNNIAKRLNLYGVVSYIGDPARLDTSGKEPAEDVDTIMRVLRIDNDQVRNTLIINQSIDQTVLIKNSGQAQQWINGGHPRYTKAVIAMASQRNAGTRYDWSRSGAPKSSAIKAWEGSFRMKTDREEQLRLAREALDEAKRAAETANQRHRSAQQELKVAQQAATKHKRDATSLRVEMQQSDTAVDDKTAEIDLNRPQDGKLQQLQRELEETNQEHDAIHGTYTDSVEQVDKLDGNARELKGNLDAAQAEVEHINTLIEQADAKLKRREVQREQSLLRKNELLDDVDHIRGRLAVLEQKRDDQKVILEDWTGAALTISERVETEPGITADMYDARINKLNHEIATMTARAGGTEEELTRDWEKKYLEYSNAKTQMDELNGVRKALKETLKERHRRWGLFRKYISLRARLNFQYLLSERNFRGRMLLNHSDKQLDISVEPDSTRASDSGRQAKTLSGGEKSFSTICLLLSIWEAMGSPIRCLDEFDVFMDSVNRAQSMELMIGAARRAVGRQFILITPQSMNNVKYGTDVKVIKMGDPERGQRVLAVNGQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJN1</accession>
    <name>A0A9Q8PJN1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768022.1">
        <property type="nucleotide sequence ID" value="XM_047912416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJN1"/>
    <dbReference type="GeneID" id="71993146"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13268"/>
    <dbReference type="OMA" id="DINQGTR"/>
    <dbReference type="OrthoDB" id="3485059at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF4">
        <property type="entry name" value="CELL WALL GALACTOMANNOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="181" mass="19167" checksum="2883DC5EA2133932" modified="2023-09-13" version="1">MLASYFLLPALALASPAAELYKRSGASITQAIGYINNNITTVNNTLNTFNKPKDAITALTLQIETESLIKSVNNAASVCKDSAPLSDSESFDVATAVLNLQPNINSLLDNLVAHKPQFMTALFGFSADPIVKVDLVNAKKGADDFGTALTPKLTATYQGAAPVIIQQIDDKFDQAIAAFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK06</accession>
    <name>A0A9Q8PK06_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_13088</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768160.1">
        <property type="nucleotide sequence ID" value="XM_047912236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK06"/>
    <dbReference type="GeneID" id="71992966"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13088"/>
    <dbReference type="OMA" id="SFIGTIC"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033229">
        <property type="term" value="F:cysteine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="83"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO23794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="536" mass="59964" checksum="B045B2ADF140F7C5" modified="2023-09-13" version="1">MAQHVMGDLKVNLDPPVTDSHTSEKAADTAEIERVMSPDDDLKKGGQNYGKMDAEVAKYAEGIPITITPEENSRLKKLINKRVLSIMVFTYFLQALDKGTLSFTSIMGLPEDLKLVGQQYSWLTTSIYIAILIVEYPINWLVQRLPIAKFLGTCIIIWGSILAFHAASSNFAGICALRILLGIFEAVCQPTFLIMSSMWYKREEQVLIVSFWYCMNGAQQIVGGLLAYCFSLIPDTAAIHSWQAIFIAYGAFSVLWGVFVIWWLPDSPMRAKCFSEHDKRLMVERVRSNQTGLQNKTFKMEQVKEALCDVQCWCYCLIQICTTLPTGGLGAFANIIIKGFGFTTLEVQLLAMVLGAFIILVLFSSAWLVKKTKQNIIVMACFCIPSFAGTIVLMTVKNDDTTSTEAGLLFSYYICLSFWAAQNLGMSLLSRNVAGQTKKSVAVAMNFIAWAAGNAVGPQVFLAYDAPRYFIAFATHLGCYTLLILNLIVLRWTLRSRNKKRDEIAAAGVQEAHDETNVHAFEDLSDKENVNFRYMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK14</accession>
    <name>A0A9Q8PK14_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768264.1">
        <property type="nucleotide sequence ID" value="XM_047911770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK14"/>
    <dbReference type="GeneID" id="71992500"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12622"/>
    <dbReference type="OMA" id="GEDLKVW"/>
    <dbReference type="OrthoDB" id="1047367at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF314">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="29944" checksum="789A27C8A2BD166B" modified="2023-09-13" version="1">MLTNPTPLHCLIISAGIAGLTATLALLRSGHHITILEKSHYLTETGAALGLGPNASSLPIDLGWDRASSGAIAVRGLTSIDGETGEPRAQMDLEEFAKRWKSPWLSVHGVDLHRELRKLGESAEGLGREGDVVRKDVVPEARLSPAGKRCYRWLVERERLMADSGTMFLTEEEGYMKHVAGPEGKFVMYHCRKNTMFKFAVLLPDDEMDAEGDDLYRQGNERTVLSRRSTFAPPTRKLLSLAGEDLKVWQLVDMAPLFDSGRSVRNAECLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKW9</accession>
    <name>A0A9Q8PKW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768709.1">
        <property type="nucleotide sequence ID" value="XM_047912630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKW9"/>
    <dbReference type="GeneID" id="71993360"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13482"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="23616" checksum="891A246A57750FC4" modified="2023-09-13" version="1">MCQAAAGFRALNPPESTSPVAHPFSTQHQTTGPSTATMVQYRGRAEFSNLLLHDWKLMRREDCSREQLRTELKLKGHHISKSAAKSLSHEQLQDRLSRVDRGLMLYGRESEAELRDLCQKRNIPSTSTTTKPQLISALEKADEDRTFLRFMDLPPELRTRIYDFYFEPLHRVRWDVAPYTIPPPPITIVSKQLRLESHPLFYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL18</accession>
    <name>A0A9Q8PL18_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13776</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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</entry>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <source>
            <dbReference type="EMBL" id="UJO25277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="35011" checksum="CDCE7A5E9C062B6F" modified="2023-09-13" version="1">MASTKLTFETALATASTESSPQHIIRDNMLFRRAVWLFSITAATLQLQPQCDASTNGTSFTGEEGSELKLNSTTVRKIDAQDANQGVAVDRDHFYSIDNFSITKHNKTTGESLLQWYGGKTGPIIHLDGGVVIDGILYAPHSNYPQSPITSSVEMWNATTLEHIGSHAFGIYRGSLTWIDQDANGTWFGTFANYDRIQSGQMLPYGLTMRTQLVQFSPDWSVARSWIFPEALHQSFSPMSNSGGSFGPDGWLYITGHDAAAVYVIKIPSAGSDLIWVATIDAPDIAGQGIAWDRSEGRNGMRGGMGVFMGFRGRGVRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQA1</accession>
    <name>A0A9Q8UQA1_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_07367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906515.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987245"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07367"/>
    <dbReference type="OrthoDB" id="5422698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="27085" checksum="C3E73054DDF1BC25" modified="2023-09-13" version="1">MLPARELVRCASRMEVELDETLCHTKRPAMNYLATTYTESSPAANTLTYLMTIQHFPNIKSAFGSLLAAVLASRVTARPGMARDQTPIAHFFDDPRTNAVPGNNNATYGPVPKAEQIFTIEFLEIAPLPMPVDRYTFFWLRGLIAPQHVPALNKDALSHTTITLDQRPSNEEPDPTRASTLPLKTIARPELAGHFAIRGPEGKYLDYLSAEGKNDLLAEMLFLAMFMEEGEYTFDVVARLADGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP6</accession>
    <name>A0A9Q8UQP6_PASFU</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763262.1">
        <property type="nucleotide sequence ID" value="XM_047905833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP6"/>
    <dbReference type="GeneID" id="71986563"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06685"/>
    <dbReference type="OMA" id="HFSVSNW"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000005">
        <property type="entry name" value="Similar to RNA processing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="204"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="433" mass="49000" checksum="BF05D263F5285B61" modified="2023-09-13" version="1">MASSNLNKIGNKIKRQEQHLKAKKLKESAKRDDRLRRRRHEDKNPHLRAQRQAKNVPQTIDSKRTWDEVDDADEDEARLDRAVNVLNPKRRKVEKDAPADEGDGLTSGKLEALEKAQERAEKGEEEDEDRDSMLDSDSEGEDEDADSASDTTSNRKRSARAPSEAPSAAPSAATAVTAATDMTVRPEALRAKFPSLFNETTHDPKVLLTTSINSTLHHEAELLTTLFPNCTYIKRTANFHGYKYSIREIASYASAPSRGYTHVVVLNEDLKKPKGLDIVHLPHGPMFHFSISNWIPGARLPGHGNPTNHYPELILNGFKTPLGLLAAHLFKSLFPPRPEIQGRQVVTLHNQRDYIFVRRHRYVFRDKKQTEKVIHGTDGKPMKGAEDIRAGLQELGPRFTLKLRRVDKGIQRASGQEWEWKAGDEKVRTRFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQQ3</accession>
    <name>A0A9Q8UQQ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763365.1">
        <property type="nucleotide sequence ID" value="XM_047905816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQQ3"/>
    <dbReference type="GeneID" id="71986546"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06668"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="45480" checksum="B70102F2F8A747E0" modified="2023-09-13" version="1">MGKSRQERTAAAAAKAPKKDKRYPNNARDKNGNRISKPSQRMPSKPAWKASAALLDAAIAASEKARSTKLNGDKSAPEDVLSPDTKISMVTDRKYDIEVTWKNIRRYMVDAHHLEKANTCETDPTKVALREEEIAQCLKEAMALEDRLRELGRPYYFTYAWLYSDHPGADRSVWWDRIGRNRSEAEELMAPCYGLTDCSDTEDDHVPAKNNKDSPERLSTSPSAASPSSTKGALPSSAPLDPQQQPATGAPDLQYLPNASKQPKSALPSQTFPGSSKAAPPPTPPPSPESKDEDPKPSEKAPPISNDQQDNPPEDTKNATESSSEADAAKPASPPLEHASRDPPTDESYDDEDSGGEEQGDQTGDAASDDAADQEQGDQTGDAASNKAADQEEGAAEDDDNGEEETKNKDDEESDDEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQS5</accession>
    <name>A0A9Q8UQS5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidyl-prolyl isomerase CWC27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06842</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763379.1">
        <property type="nucleotide sequence ID" value="XM_047905990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQS5"/>
    <dbReference type="GeneID" id="71986720"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06842"/>
    <dbReference type="OMA" id="CKNFLQH"/>
    <dbReference type="OrthoDB" id="442970at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="22"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="491" mass="54519" checksum="661AEFFB6DF4F897" modified="2023-09-13" version="1">MANLYNLEPQPTAKVILNTTSGDIELSLFAKQTPLASRNFLQHCLDGYYTNTIFHRLLPGFIVQGGDPTGTGQGGESALENGGTFEDEFHSRLKYNRRGLLGMANEGANSNGSQFFFTLDATPELQGKNTMFGRVEGDTIYNLMKMSQDVEMASEGSERPLYPTKVTGAEILVNPFEDMVAGVKVAPRSKEEKTQVKKRKKPMGKQVLSFGGDEGEEEMAPVVKKVKANPKLVAVEPEEPEEKVAKIPKKEKKLAKPKDEVIVPEEDIAIPQTTTAGAPAKIEEAEDSEEESETEEDRRKRKLDHTNAEIQALKASMKRTVDIKPQKEEKPKSALEAMIPTTSTRGRKRGKATDEKGAFNLFQTFKQRLDTLPTEAAPEPANDTTKTHPNPEPNPSSDADDDEEAALCDLHFIANCQSCKSWDDEKPDGEAEKDGDDDPGWMAHTLTFAKDTLGKDLEWKRKMEEIGVIDPREKARAIKEEKRKGKEKAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQW8</accession>
    <name>A0A9Q8UQW8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07742</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763514.1">
        <property type="nucleotide sequence ID" value="XM_047906890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQW8"/>
    <dbReference type="GeneID" id="71987620"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07742"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901991">
        <property type="term" value="P:negative regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="618"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="656"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="675" mass="76371" checksum="97C0B9E9D66A2998" modified="2023-09-13" version="1">MKGFRQRVHDQLSRAKDRDGNKLAKKKDSSSGTASPAGQSPAGSQHATPTSSTSNLVDQRNKPLPTDGPTQSHPGAPMPGTANNMNASNNTAGPQSGSFAQHGASFNGQQSPGGLNSQGPSTPGRLGALPPSVVISPSAPHVPPPGAAETMPQDLAPPKAGQKSLLFDRLQATPKADTVPEGVRTPKRQHSSRFDISDQRQRELEKLPGFHEVPPNRRAELFMQKLDQCNIIFDFNDASGDMKSKEIKRLALHELLDYVAQNRQVISEPMYPRVVEMFAKNLFRPIPPPMNPQGEAFDPEEDEPVLEVAWPHIQVVYEFFLRFIESQDFNTNYAKQYIDHQFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLNLRSYIRRSINNVFFQFIYETERFNGIAELLEILGSIINGFALPLKEEHKLFLTRVLIPLHKVKSLSMYHPQLAYCIVQFLEKDAALTEEVVLGLLRYWPKVNSTKEVMFLNEVEDIFEVMDPAEFAKVQEPLFNQLAKSVASPHFQVAERALYFWNNEYFCNLVSDNVDVILPIMFAPLYENSKGHWNRTIHGMVYNAMKLFMEVNPQLFDECSHEYTEQQNNLEAVKANRQAKWDRLSQLAEQMKQNGHAPAVRPPQGNFGNSSKSPTRTDDGDPISMNRLRIDDERRAETQRHANSVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR00</accession>
    <name>A0A9Q8UR00_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763578.1">
        <property type="nucleotide sequence ID" value="XM_047906356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR00"/>
    <dbReference type="GeneID" id="71987086"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07208"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="104" mass="11767" checksum="906C2200F0B33A14" modified="2023-09-13" version="1">MRQQENPTTDPPESEPEMDEKFDTRDLESGPPPYGSCDQNGVPAYCHSCTDQSSRFQEDNIDDEDPENEHKRGWEFRVVLLVAYVVIALVIFTLLHTAPTPSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URH7</accession>
    <name>A0A9Q8URH7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10715</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764116.1">
        <property type="nucleotide sequence ID" value="XM_047909863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URH7"/>
    <dbReference type="GeneID" id="71990593"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10715"/>
    <dbReference type="OMA" id="WSKTWLK"/>
    <dbReference type="OrthoDB" id="4088536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="7">
        <location>
            <begin position="49"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="8">
        <location>
            <begin position="217"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="349" mass="38498" checksum="95EEC97FF4C1C5DC" modified="2023-09-13" version="1">MAPQSAEDVKVLNNLIASTLALVKQFRPSISTASTTPAIDNPPNPLRVLRDSASLLKAHTTKVSLLAINKPFTPSAITKVLRDLTSTCLPAMMSAVQICTQEKASYSTLVEKEVQARVSRVFREMENLLNELQSIANGGSAPARRDSLSSTGVVWESCDALIELEKMGLAGLAVKKAEQYRDAVKDAIEELQEWKEGEDLEHEGVDELLDGDDEGIDGDADLMEDIFNAANSLPKDRPELKELVEQAEGKLKKIVLLFNALIRRRLKPFEDGEKGKVKALDAVVEMLRSVQKDVDDLANCFYELNEEDVKVALETCVGHAKEACKIAKLKDGKEDEFTTWSQKWEEAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URM4</accession>
    <name>A0A9Q8URM4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Heavy metal tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_10473</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764238.1">
        <property type="nucleotide sequence ID" value="XM_047909621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URM4"/>
    <dbReference type="GeneID" id="71990351"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10473"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF651">
        <property type="entry name" value="HEAVY METAL TOLERANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="292"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="611"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="198"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="885"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="898" mass="99458" checksum="138596E80DD30957" modified="2023-09-13" version="1">MNITNSISMASIASAALALPVLHYIAPVATATYFISAKTAATCLLQEPSKRGKLSLRRYGSSALQLTILATVVAEAVTTITQAFQDSTFAPAQDYVIYLFASFVLHGCFSLGLIENEHPLWHPYLGAWLIALAFDFPLIVLQGLRIPEDGYAKGRMSICVLRSAALVALSILASWCILSDRKRSIRLDDESEALLAANGHEASTNGTRTKPITSPRDSVLASENGDTGDDNEERDDGFDSDSEEPEEDKKLRAQQKQRLQESGSWFAYLKEFNIFIPMLLPRKNRLVQACLVTIGVCIFMNRALNILVPRQVGIVVNELTEAYGTGVVPWRALGLWMLYTSLSSGVGIGLLKALAEMPVNQYGHRMIATTAFQHIMDLDMHFHNEKNSGELIRVIDQGSTLQDLLSYMLFDIGPMFFDLAVAFVYVSILFDVYMSVIMFAIGISYVWIGAKVTAWSIKQRRDFNSAWLNESRVQNEAINNWSTVSHFNRGKYESIRYDESVVAFNLAEWRYYLAYYLGGGFQSGIMLIGRLAAMSLAAYRVSQGSAPVGNFVTLSMYWSSVEAPLRSVSYSIRKITSMLTDSERLLQLLTTKPLVNEQPEAKDIEIKEGTVTFENVDFSYDPRKSTLRNINLEIKAGQTIALVGETGGGKSTILKLLYRYYDVTNGAIRIDGQDIRHVTLDSLRDSFGMVPQDPALFNTSIMENIKYARLDATDEEVKEACRAAAIHDKIESFPDGYKAKVGERGVKLSGGELQRVAIARAILRQPKIVLLDEATSMIDAETEATIQLAFKRLSASRTTFVVAHRLSTIQHADQILVIHDGEIVEHGTHAELFRQKGKYVALWSKQLNKDVQDVGTSLDVQKADEVLKTDGSGEAQVRVQDVMDASSSSKAGSSSEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URS6</accession>
    <name>A0A9Q8URS6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phototropin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09961</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764414.1">
        <property type="nucleotide sequence ID" value="XM_047909109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URS6"/>
    <dbReference type="GeneID" id="71989839"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09961"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF9">
        <property type="entry name" value="PAS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="449"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="622"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="793"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="645"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="801"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="811"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="845"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="854" mass="94495" checksum="9DD79FA3A16180F7" modified="2023-09-13" version="1">MEAAVKSSNNSNRLFHKIGKRLRPTRSGELLSGVPTPTADDSPVSPALKDLPAYTPVPVPERKSSAKREATDPEQQTQPLVPRSDNPNDRPFRHNFSSQDADDISLGLSGFDDDLLRPASPVSPMGPRAAPGTAMTEDSVTLPHRGGYGVQHALFPRPTITPYPDSHNVIRQPTPVQEHQQPRGRTRNQALQPPAPVSKPPTPAPSSSSPKSSSAKDSMDESYQHLAPKVLSPPESIKDYAGPEKLGSAALAQLQVPSADKSDCLETELSYEDDPNSWDIIKPNQRSEQQWDKDLYSLEKRAEQLYSAEHLHLILEDADFHAKFAAFLHKYRPWRAPLLSYYLDACKALKALQYTNALTEMLAKRTTVYGNTFQPPITPPGTAANNQLKDAAQRAFDALLSEDLHWYIAHTYIGIVCSVMRSRVTGNLPAPLREASHGLAEVFCITDPTRRDNPIVLASPAFTRHSGCNMDYILGRNCRFMQGPGSTVDSCRRFAVSMEKGVDHSEIFVNYRRDGSPFLSLVMNALLTDSHGNIRYYLGAQVDVSGLLKNCTGLDSLTRLVEKQAVEARTGNDRRTGKSADEAMRQLSQMLNGNELDIVSEHGGLLQKDSKLRDIQEQKTATLQHANTGRLPSGPPRVLIADGSSSDESDREPEEPEIEQFPIPVERLDAGLPAPEINLSGVYKYYLLVRPAPSLRVLFASPTLRFPGVIQSHFLHRIGSSKMRNSLNGAFQEAKVITAKVKWLKSPKQDGDNETGDLHGPTETRWIHCTPLMHHTGAVGLWMIVVVMPSEKDEDHHHNLNSKASRGLNHQTSYQSESQSQSQSGQVRQDRVPSRMVSYQSEGSSSRRDGMKMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URW8</accession>
    <name>A0A9Q8URW8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764534.1">
        <property type="nucleotide sequence ID" value="XM_047909548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URW8"/>
    <dbReference type="GeneID" id="71990278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10400"/>
    <dbReference type="OrthoDB" id="3647879at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="328" mass="36188" checksum="765EE8BF99C90757" modified="2023-09-13" version="1">MLHSCHGIVAFSHDLRSSTSHFHQPPPVNTTSRIATLLLAPHHGAVSCVAHYFTNTTAAFWRLKLDTREIMAPYTTYFNYLPTSLAGPARPVYNTVVGADFNRDAAEEMHKRSTKLEHYDLEVNEEFDAEEEWTGISQSDLRDGERRGMDFEDEAFIIRQSGRPRNLSFKLSEKATEAACEAAGVSREYLGIALKYVTLEMARDIGWLTHCKTVSDVARAAKRKFPLLEDMQRAFEEGSGKSMRPRSGGVSEVGSPGAEDSNEEAVVASTAPRTRSGSQPVYDPEVHAGVEMVPVVARSRGPYASDGDDEDDGDSEHSVDSQGFTRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US61</accession>
    <name>A0A9Q8US61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764806.1">
        <property type="nucleotide sequence ID" value="XM_047909304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US61"/>
    <dbReference type="GeneID" id="71990034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10156"/>
    <dbReference type="OMA" id="PFLVCEG"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="28792" checksum="0F9328636F4589F6" modified="2023-09-13" version="1">MASAVSNLAASNNTRFNAEAAAWDSRPFVHEASQGAAKAIRDLLAARPGDKPVNKLEVLEIGCGTGILSFLLAPHVQRIIAVDAAEGMIDVLKEKLTKPHAPKNILPLALLLDNPEDAALPPADPLDVNASSGPRLKVDLITSHLVMHHIPDLVPLLETMYACLAPGGRVMLTDFEDFGPEAKRFHPASKMDGVARHGINARWMEAILLQVGFTDVEVEARWTMTKNVEKYEGEFGGAYGGDAQELTSTGKGEDMQFPFLVCYGAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US64</accession>
    <name>A0A9Q8US64_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">C5a peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09927</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764834.1">
        <property type="nucleotide sequence ID" value="XM_047909075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US64"/>
    <dbReference type="GeneID" id="71989805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09927"/>
    <dbReference type="OMA" id="FNHPALG"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="163"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="394"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="11">
        <location>
            <begin position="638"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="928" mass="99435" checksum="67D7763FEA0D30B7" modified="2023-09-13" version="1">MFYRLATYLAVCTVTFVAGVLSGVLVAELQPSSNIESFQDLLHNIAAQYLDGSPPVVKHCFRGSPIFWGLVLEHQGIDRITLRNIEESLRLEFPDFLRFWDLGASSQRSYGNISQAARSVLSPLLPTHSAGDESSQGQHTKSELRAIHELTGVHELHKRGIVGHGASVAVIDVGLDYLHPVFAATSDRSSPLRYTTDFVGDDFVPGANLPQPDSDTYTECEIHGTHTSALIVGRQQSVGFVGVAPGAALDHYRVAGCLEVNRFDDEILIEALLLAHSRRVDVISLSLANGYGPYPSELVSDIIRRIVQEGQTLCVVSAGNTGWAGPFSAVSPAAAAGAVSAGAVHSIHVIRSNPMAQATYWVAGEQRSFMFEWQPSFPSRFPQSLRLYVLSLNASIPNDACGDHAADLGLPDDLEGHIVLIRRGGCAFQQKIDNVLSHGAAYVLIYDNTPTDGWDIFLYDNTFHGIRGCGSLLAETGLKLANIFAEADNVILEMDSNFTLLPKIRTRYNPLYPAGSLYTGGSWGPTGDLSTFPSILGPGGSVWSAVPRSAGGFGTYTGTSISAPYIAGCIALLRSVYPDWAAPDIVRALIHTATPLPFSDGNKSYDNLLAPVWQQGGGLVNMVAALESRTAISVSFLNFNDTEFYRVATFTITNLGDRSASYELQYVPAATVDTLDSRRHIIAFAEDPASSDQATAQFLAHTRSGDQALVDLTPSSLHLPSGGSAVIHAEVNLANVADEKTCPLYSGYIKINSSHDGVLSLPCGGIGCRIGDVSTLPPNWNLTFLAAARYIDSDNPNSIIQPAAANTTFRLPASGNPGFDLSSEVMYPMINIQVAMISPHAVAFLETCSSVSTSANANSTLSVPVDLHGTQIAGGFSRIVPRRLLWAGKLTNGSLAISGSYCLQICTSRTLGSVLDCTKTVQFNLIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USB9</accession>
    <name>A0A9Q8USB9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764987.1">
        <property type="nucleotide sequence ID" value="XM_047910595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USB9"/>
    <dbReference type="GeneID" id="71991325"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11447"/>
    <dbReference type="OMA" id="PNGEKWA"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000002">
        <property type="entry name" value="Sucrose isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF179">
        <property type="entry name" value="NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="6">
        <location>
            <begin position="67"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="702" mass="80627" checksum="5CC26B7C2AC0B884" modified="2023-09-13" version="1">MANKAETNGIGGHSTTASAQGETSAFPTLQPVPNVSPPNGKHVIPSDYPVLQDVKGRPWWKGVVAYQIWPRSFKDSGANGIGDLQGIISKLDYLKDLGIDVIWISPTFDSPQKDWGYDISNYETMHRDFGTLEDMQQLIDEAHNRDIKILLDLVITHTSDEHPWFLESRKSRDNPKSDWYMWADKRPGNMIDGEMIEEPSNWRAAFGGSAWEWVPEREQYFIHLFLKSQPDLNWECEAMRDAIYLSAVKFWLDRGVDGFRIDTANRFCKDPNYPDAQRTVAGRWQPGSKYYINGPKMHVWLKELRARMVADFPEKDLMLVGELPLTPYEELLRYVSPEEKELSMVFDFDMVKLGNNDNPDEIAKHEVSNYMDKDKSYTLPLFKQTVKKVQSLITDTNAWGTVFMENHDQGRSIPRYATPNSKYWRQAGKILAMLQTTLSGTQFIYQGQEIGMLNMPHGWGNNEFKDPDTIDYIETYIEMNHKHDPRASDKAREGVFKVGRDNGRTPMQWSNSPNGGFTGANPCWMRVNDNYSYINVEAQQQDPDSIFHFWKKHIAMRKDYKELFMFGTFALYDIANERMMTYTKMSTDGQMALIILNFSDDDMPLNTLQRHLLGHTYRLMSSNVQKPGDHLEPWEGRVYMVRDGLEADMPGQPSNIGQLQDLMPTRAKGVVSSMPMTGHPAGHQPRRESKLDGTQWISAASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USR9</accession>
    <name>A0A9Q8USR9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765438.1">
        <property type="nucleotide sequence ID" value="XM_047910457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USR9"/>
    <dbReference type="GeneID" id="71991187"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11309"/>
    <dbReference type="OrthoDB" id="66726at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="749"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="813"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="950" mass="104701" checksum="A83BB17B2101E8A8" modified="2023-09-13" version="1">METANNSSVIPSMQDLFLVLPRLAQRAGSFGVGLFHMPEAMEGIAGKIMNGGSIIADATGQHTTANSTITNTSIAFAQNTASTLESTIRGAWRNAVEEESTSIFMSIAQGVGKLKQFGGIFSYLTSKWALTTFTVAIILNRTQFYASTRETLRLRFHLRLVLYSIPIMLFLTQLVTILQAMRCQTSPDFPQLRYGDPLKQLSIDFAGEGGFLYDLNTKLLFWQDDASCCNARRMSLVGMDDDRSGLRGSMSLLYCFFLALCTSQFFETLTCALQGKQPMPETGMTIFEHSLAFAECEAMISSALGFGFFGLKSADGSGSSTENSGPLIMRSELLQRLNVPPEVLLVCLISCFSHLSSAFLATLNIRHRVRLVNTAIWACCYMAAFFWSFSKIWYGPLDHVADLGVLRFPTVCVVGFIPHLLILIGIVICSVIYGIAILITALSIPPDAAEGLSIKQRFAWAFNNLQANVQFSSNPSIRIKMSEDFYTTLLKIGFNVLTAASEAVYLNEGSRVHIAQMTWLEQKRIDEISASMQARKAPAVPSELLGDGIARGVGYIDHQNVAIGQSPYARERKSKPTKKPDGERPAGADLDSGLGLSQRRSRMQLTFDFISGISWLVIGLQAQLALNMLHKLGIEHRPAWLLKAAGIVERQRKPSAHDRPRKSDMLDFYVLDAKGNPVIPRVEDLDVESEMRRRAQHSKSPRGLAGVDDELYNWWRRGGRFGDIDQSGDYAASTASQDDDLTSVISVSTNASEIDEQEDSGRRTPTQRDPYADWLSREGTPATSDAGIDLSILSRLLNPQSSDDRAEARLLSHTLQSNRPLTRSQYRRTTDRQRGELLNGLRSASKASASSPSITPEDEEADLENFIIGQRQKSKARAQKSGTWESGAEGMGEGGPQCVVCQSTPRTILVWPCGCLSMCDDCRVGLAARNYTKCICCRTDIAAYSRLYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTT8</accession>
    <name>A0A9Q8UTT8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome quality control complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_09042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766635.1">
        <property type="nucleotide sequence ID" value="XM_047908190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTT8"/>
    <dbReference type="GeneID" id="71988920"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09042"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000003">
        <property type="entry name" value="Zinc knuckle domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="8">
        <location>
            <begin position="549"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="9">
        <location>
            <begin position="988"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="441"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="716"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1099"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="805"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="828"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="874"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="889"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="927"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1108"/>
            <end position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO22269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1123" mass="125376" checksum="9644B54CB0896758" modified="2023-09-13" version="1">MKQRFSSLDVRVIAHELSNSLVSLRLANVYDLSSRIFLLKFAKPEHREQLIVDSGFRCHLTSFARATAAAPSPFVARLRKFLRTRRCTAVRQIGTDRIIELHFSDGAYRLFLEFYAGGNIVLTDAELTTLGLLRSVSEGAEHEQYRLGSKYDLSLRQNYEGTASLTKERLRDGLQKAVERQQAEAHKPGRKIKKKVGDALRKALAITTTEFPPVLIDHALHVTAVDRQIEPEAVVGSDEDLDNVLKALQEANRIVQEITRLPVAKGYILAKRKVPKADEANGTVDDNQNVMYEDFHPFKPAQLEIDPANVFIEHEGFNKAVDDFFSSIEGQKLESRLHEREENAKRRIEQARQEQEKRITGLQQVQDLNVRKAQAIEANVERVEEAVAAVNGLIAQGMDWVDIGRLIENEQKRHNPVAELIKLPLKLHENTVTLLLSELADADDEHMDETDSEPSDSEDEDHQSKVKPASKPEDKRLTIDIDLAASGWSNARQYYDQRRTAATKQEKTAQASQKALKSTEQKVMADLKKGLKQEKEVLRPVRKQFWFEKFIYFISSDAYLVLAGKDAQQNEMLYRRYLRKGDVYVHADMHGAASVIIKNNPSTPEAPIPPSTLSQAGNLSVCTSSAWDSKAVMSAWWVNADQVSKTAPTGEYLTTGGFMVRGKKNFLPPAQLLLGFAIVFQISEESKARHVKHRLQQKPADYLATPDLTDGETIAESSAAGDGEESDDSDDEFPDAGPAPRIEEDDDDEFPDAAPRPDEFSADESPEYQRERTYGAYDDEVNEYRSGQSNPLQAGALQPAADENHDTEEGDDEHDDDDEDDDEAESPNGETATKENAATESTMTAGDEDGHTEADENAASAEVPLTNRERKMKNRLDQGKPIHNEAKVKQSKGQRGKKGKNKKIAQKYADQDEEDRELAMKLLGSKAGEEKRQAEAKVKAEKTETEEEEARARRRAQHQKAQREGLEAEEIRKLNLEEGVEILDEEESSQLTQLDALVGTPLPGDEILEAIAICAPWGALTRYKYKAKMQPGQQKKGKATREILGRWTKAASDPRAIDNQAQDNERIWPREAELIKNFKEVEVVGVIPVKQVRVMMSGGADAAKGKGGRGGLGGRGGKGSKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTX5</accession>
    <name>A0A9Q8UTX5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766634.1">
        <property type="nucleotide sequence ID" value="XM_047908488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTX5"/>
    <dbReference type="GeneID" id="71989218"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09340"/>
    <dbReference type="OMA" id="CIVLNAT"/>
    <dbReference type="OrthoDB" id="3935813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="15520" checksum="EF36D96C10CB0991" modified="2023-09-13" version="1">MSKPAGSSWDFEVFKTTASEVEKDRILAIYLNSDVTNTDWEKVTSDLKSASANSVKVSHSNTFKKVEKAGGKIGVAATAPATPKTPTSGKKRKSKAEMEDKVDADSTPKSKKGRKTKKEIAAEAEAEAEEGGEAGVKVEQNDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTZ9</accession>
    <name>A0A9Q8UTZ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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                <person name="Chen L.H."/>
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            </authorList>
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            <end position="26"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="233" mass="26662" checksum="43EED0308400B08E" modified="2023-09-13" version="1">MSSKTHQEEYGWTAVPRGRSNVPSEQEAKTANVQVNFDSIWPRTELVKKSQAYVKEKLPEKTYNHSLRSTATHFRSWIEQARDQFFETWALTCLFHDIATTEENRNATWLSFEFQGGFIALQELQNYGAPVSQAESVCESIIRHQDPGETGTISRMGQLVQLATELDNMGWQPYLVDKAVIEQVVKQLLRKKWSSCFAQSIQDEIDAKPWCHTTAIPGFKEAVAGNRLMEPYD</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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            <name>heme</name>
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    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
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        </location>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVT7</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVT7"/>
    <dbReference type="GeneID" id="71993561"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13683"/>
    <dbReference type="OrthoDB" id="5424391at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="362" mass="41358" checksum="5B318D48FB24DC0A" modified="2023-09-13" version="1">MTTAQQSEDTTALAPRSALEVAEVKAQRQLSTFGEYSPAAIRLKNDIVTDQVEATKHLQSVIADGTFTLETARVCLAGERERLAKYKRKERPAIMRSEGKPFARTIMTQLWTDEKLWGPLVSDDHLHTGNLCYFAIFEGLESFLVDWLRAEIDQPFVPEKEHMWRGHLLGSMVLAHAALSIGHELDEAIRCMFRVETLRRRLTAEAPEDQRPATAYLSLRPSVSILTKQIMTGQFRHTDERLYNEFCSLATRYRSKSYTERLEKNYRQAAFSLYHPKSPDHRLALACLKENVAQATTPEDLKILRNMMGLSNISLKRFILRAAYLASRSTHHADATFIREQGLRLQQVSTALPYDRYKTVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW32</accession>
    <name>A0A9Q8UW32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RAD52 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768959.1">
        <property type="nucleotide sequence ID" value="XM_047912628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW32"/>
    <dbReference type="GeneID" id="71993358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13480"/>
    <dbReference type="OrthoDB" id="206565at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.80:FF:000001">
        <property type="entry name" value="DNA repair protein RAD52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004585">
        <property type="entry name" value="DNA_recomb/repair_Rad52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00607">
        <property type="entry name" value="rad52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="592" mass="63237" checksum="808649828129D6B1" modified="2023-09-13" version="1">MPAPGDQHRDNANTINPFIDKTPHITEYTAQEIATLQSRLDKQLGPEYISTRPGNGGGKVHYLAAEKVINLANEVFGFNGWSSSIINVQIDFVDENPTNGKINLGLSTIVRVTLKDGTFHEDTGYGHCENTKGKAAAFEKAKKEAATDAMKRALRNFGNVLGNCLYDKDYLSKITKVKATPSRWDEKNLHRHPDFAPIKQEPVTQVPQQNNTSAIQRNTSVQSVQSAASFGSGEFEDDFGGTTFDETDFNHPDEVMLEDSTITNGAPSPARPAVHGQNQKGQRQGVPRTHSMPQMRPPNQQIPAQGNVQPPAPVQGLQAPQRPQPVSRPPMIAGQPAARMLPPQTPGNAQRPQQYNHGQLQPNHDGVRSNPSSGTMSDSPSNQAPRIIGVAKNQPQGHGPNEPTDEHGFPIPREPPQGIPSGFVTGRKAEVFNQPGEARPTEGNIAFNPHADSPSIRRTQGINPGKSAPISRAVFSNGHTQSPAQQQPAAAGNGFQSAASNGFNGAQRPAGANYINPSADMSRKIGMPGGPGGMQNRSAYRPPAAVKRPAMADVTNTHGMDGASDPKKAKVDDAATANGENAAARDPNGVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXV1</accession>
    <name>A0A1P8YXV1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endo-chitosanase</fullName>
            <ecNumber evidence="10">3.2.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_06669</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">0WU</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of beta-(1-&gt;4)-linkages between D-glucosamine residues in a partly acetylated chitosan.</text>
            <dbReference type="EC" id="3.2.1.132"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 75 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.132" evidence="10"/>
    <dbReference type="EMBL" id="KX943173">
        <property type="protein sequence ID" value="AQA29344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763366.1">
        <property type="nucleotide sequence ID" value="XM_047905817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXV1"/>
    <dbReference type="GeneID" id="71986547"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06669"/>
    <dbReference type="OMA" id="KLCFPNE"/>
    <dbReference type="OrthoDB" id="4756206at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061:SF6">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041001948" description="Endo-chitosanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQA29344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="262" mass="27864" checksum="A8B7E51A3B9AB410" modified="2017-04-12" version="1">MIVPTLVRLLAVASLANAYSLSTYPKLKAVYDRYNKANSECSALLQDGFYDAGQTKDGHYYRYCGDLGGGLKAIFLHRNGGGLNDMDIDCDGAQACPDDPTFQGQTSFKTAYGGYQGVQELSRAAGAYVSDLNATRHPYVVFGNEGSKPTFNPKDYGMVPLSVMAVVCNGQVHYGVWGDTNGGTSTGEASLAMGNLCFPSEGLGGNNGHDANDVLYIGFRNETAYPGYGGKNHAKWKGTTKEFEDSIRGLGDSLVKGLLGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4N5</accession>
    <name>A0A9Q8L4N5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate--CoA ligase [ADP-forming] subunit alpha-1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755110.1">
        <property type="nucleotide sequence ID" value="XM_047900267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4N5"/>
    <dbReference type="GeneID" id="71980997"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01119"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000017">
        <property type="entry name" value="Succinyl-CoA synthetase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000340">
        <property type="entry name" value="Succinyl-CoA synthetase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF6">
        <property type="entry name" value="SYNTHETASE SUBUNIT ALPHA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="2">
        <location>
            <begin position="48"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="709" mass="76416" checksum="345A93A28C4E8475" modified="2023-09-13" version="1">MTMASLRSSQASSILQNTTSRLSRCSRRPFSSTQFRSGYEDTVQNLRIGKHTRVIYQGFTGRVATGNAKDSIAYGTNVVGGVTPGKEGEHIGLPLLPDLKKAKEQLKPDATAVFVAAPHCGAAIEEAIEAEIPLIVSVAEHIPLHDIMRVASILKTQSKSRLVGANAPGIIAPIGFCRIGFQPLPTFAPGHIGIAAKSGTLSYEAVASITRSGLGQSLCIGMGGDIIAGTNLVDSLKVFEADPETEGIVLIGEVGGKAEEDAADWIKDYLKRTRNPKPIAALVGGKNARQTTIMGHAGAWAARGEHNSNEKYSILQEAGATMVDHPEKFGGVMKTLLEQSGRDVSKIQANVQQQQKRGYHTFRRSPAMSGATYGPKLQPRVNAGSREQQRGLFIAPELVPVPLHPYLSKVTGLAIALDEAPKDGYYLGILVDRTERSPCIAVAPTADPSAIDARVKKFPYDWREGPSESLISQAIQYLQLDSAPQSAKQQAHGLIASLVKMYKEKEAIILSGCVSIGGSGNLKLHQPSITLMFDDAAYRSKKRQEDIHRLRQKDREVPEEVEAEKDGIVYVKYDDPQANIGTLVNGAGLAMNTIDALKLHGGRPVNFLDTGGKATSETVKKSFELILQDPRVKVIFVNIFGGLTDGGMIAEGILLAFKEVDMKNVPVVVRIRGTNEEVGQKKIAESDLGLDAFDDFESAAKRVMEIAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5B0</accession>
    <name>A0A9Q8L5B0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Multifunctional tryptophan biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Anthranilate synthase component 2</fullName>
                <shortName evidence="16">AS</shortName>
                <ecNumber evidence="16">4.1.3.27</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">Anthranilate synthase, glutamine amidotransferase component</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="16">IGPS</shortName>
                <ecNumber evidence="16">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="16">PRAI</shortName>
                <ecNumber evidence="16">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_01761</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="16"/>
    <dbReference type="EC" id="4.1.1.48" evidence="16"/>
    <dbReference type="EC" id="5.3.1.24" evidence="16"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755521.1">
        <property type="nucleotide sequence ID" value="XM_047900909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5B0"/>
    <dbReference type="GeneID" id="71981639"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01761"/>
    <dbReference type="OMA" id="EPIEWAN"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000136">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000031">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016302">
        <property type="entry name" value="Anthranilate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001382">
        <property type="entry name" value="TrpG-trpC-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="17">
        <location>
            <begin position="27"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="18">
        <location>
            <begin position="254"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="19">
        <location>
            <begin position="572"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR001382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO11155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="769" mass="82982" checksum="CC487243BD731A89" modified="2023-09-13" version="1">MPGIDLIDHSPQHPQPAAKIPTASNVVLIDNYDSFTWNVYQYLVLEGAEVTVYRNDQVTLDNLVAAKPTQLVISPGPGHPVSDSGISKDAIKHFSGKIPVLGVCMGEQCIYSVFGGTVEQTGEILHGKTSPLRHDGKGVYAGVEQDLPVTRYHSLAGTHPTLPECLEVSSWIATGPDGGKGVIMGVRHRELLVEGVQFHPESILTKDGRTMLKNFLQMQGGTWAENERLQKQTANTSPTAVQPQANGDKKPSILERIYDDRKVKVAAQKQIPSQRPADLQAAYDLNLSPSNISFPERLRKSPFKLSLMAEIKRASPSKGIISLSACAPAQARTYALAGASVISVLTEPEWFKGSIEDLRSVRQALEGMPNRPAILRKEFVFEEYQILEARLAGADTVLLIVKMLDTETLTRLYKYSQSLGMEPLVEVNTVEEMEIAVKLGSQVIGVNNRNLTSFEVDMETTTRLMETVPKETIICALSGIAGPKDVIPYQQNGVGAVLVGEALMRAKDTANFISELLGGDSKAINAKPQRKLLVKICGTRSAEAAEAAIQAGADLIGMILVKGRKRCVSTETALQISQVVHNSEKTATRVTDASTEAEGKASSFFAHRAAHHIQHPKRALLVGVFLDQPLEYILEQVKLLNLDLVQLHGSEPLEWASLIPVPTMKAFKPGHAGLATRGFHSMPLLDPGSGSGEKLDVSSVQSLLQGDDGLRVILAGGLTPDIVASTVESLGEVKAQLAGVDVSSGVEVDGEQDLAKIRAFVQAAKDVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L631</accession>
    <name>A0A9Q8L631_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755775.1">
        <property type="nucleotide sequence ID" value="XM_047900359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L631"/>
    <dbReference type="GeneID" id="71981089"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01211"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="381" mass="43178" checksum="4253810FC09A5DD4" modified="2023-09-13" version="1">MSKLLSERLTSIVPLATPRHFTEMPLIAGSGQPRVILGTMTFGPDASGGARVTDLDTYKKVLDHFQSKGYNEIDTARVYVNGKQEAWTRDAAYKERGLTCATKWYPHEDHAHSAEKIEEILNQSLKELDTQCVDIFYLHAPDRTLPFTTPLKKLDELHKQGKFVQLGLSNFTAAEVAEVVTHCKYSNWVRPTIYQGMYNAIQRSIEPELVATCRRFGIDIVVYNPIAGGIFSGKYKSNEVPKEGRYSDSMSYGKMYRKRYFQDATFDALAMIEPVVQKHNLTLLETAFRWIIHHSALKIKDGNDGIIIGVSSQEQLESNLKDIEKGPLPEEVLNVLDEAWLVTKPTAAHYWHKELKYTYEDPGFTKKIEEDLAALSGVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L647</accession>
    <name>A0A9Q8L647_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S10-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755882.1">
        <property type="nucleotide sequence ID" value="XM_047900797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L647"/>
    <dbReference type="GeneID" id="71981527"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01649"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="171" mass="19302" checksum="6ED4770A324CAA41" modified="2023-09-13" version="1">MLIPKADRKKIHEYLFREGVLVAKKDYNQPKHGEIDTKNLYVVKACQSLTSRGYLKTQFSWQWYYYTLTPEGLDYLREWLHLPAEIVPQTHVKQQRSHAPPRGMMGGDDRERRGGGRGGPRGDRGDREGGYRRREGGLGDRENKEGGAPGGFNPEFRGGFGRGRGAPPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L662</accession>
    <name>A0A9Q8L662_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L9-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755309.1">
        <property type="nucleotide sequence ID" value="XM_047899642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L662"/>
    <dbReference type="GeneID" id="71980372"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00494"/>
    <dbReference type="OMA" id="YAHFPMK"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="97"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO10943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="21849" checksum="31002E17A6A70A6B" modified="2023-09-13" version="1">MRYIYSEETLDIPEGVKVHIKTRQVTVEGPRGKLSKDLGHLAVAFSHPKKDVIKIELHHGSRKNVATLRTVRTLINNLIIGVTKGFLYKMRYVYAHFPINVNLEKNSETGLWQVEIRNFLGEKIVRHVTMQPGVDVEASKNVKDELQLSGNSLEAVSQSAADIQQICRVRNKDIRKFLDGLYVSERTNIVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6V6</accession>
    <name>A0A9Q8L6V6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756294.1">
        <property type="nucleotide sequence ID" value="XM_047901081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6V6"/>
    <dbReference type="GeneID" id="71981811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01933"/>
    <dbReference type="OMA" id="ANSDVEC"/>
    <dbReference type="OrthoDB" id="3942467at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="19244" checksum="6D8A4660346253EF" modified="2023-09-13" version="1">MDSIAHLTQKLLRERARNNQLPETAPPPYSESDMEDSDDDDDDQDEEEAEPVKLTINSAHRIHGSNNLVPTSSTPLADATKFSTLLLHAINQINAANANARDSRRRPLKVNLTINCGLEIVGDRNVVGAVGVKPKVNVGGNAVPSSVAAVAGAKRKAEDAGEDVAEPEMKKVATGQSMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7B9</accession>
    <name>A0A9Q8L7B9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756513.1">
        <property type="nucleotide sequence ID" value="XM_047899628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7B9"/>
    <dbReference type="GeneID" id="71980358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00480"/>
    <dbReference type="OMA" id="HRTQLRM"/>
    <dbReference type="OrthoDB" id="5360255at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004354">
        <property type="entry name" value="Meiotic_Rec114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03525">
        <property type="entry name" value="Meiotic_rec114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="601" mass="65555" checksum="54B13E2173DAD962" modified="2023-09-13" version="1">MAIDISLPLAKYSFAMGCDAKTNTIPWEHLTAVDLFVVIKGDSSYDASGSLSLKIIYGTKVLEKIDIDRYIERAMATKTAIQRQGTSARIEQLPIFGITSNNLLALRYRLQDGQDHRTQLRMQSAADCRQIVDLFQWRGMEFKEASARPGTSRTAGRPSTAQSDFRPLTAESSSPYFSKGPATQVRPSTTQGPALGSGSPLRQAHRPESLPHDEGSRASPASEDMPPPRVIRRGENKVASNELAIERPSSAQMWRTRTAPNQPSGVSGAAAQYGQAGPTTARPSSYNNVENMGAIRQAVEEDMDANDTLPPTLQQQDSSGALELQHHMSHSSEVPLPLTAASASSFTLPDTQDIKIAMEHELHSAVPRSRHSGSSSRPSSALDLPPLKKPQVEKRSSTSLMDQTTTPHETWATSTSVQKRPVSSADTSFYTADEQFEPRKMIFSKKTQISTAPQVSPQVAPPSPISSLSAGTTLSMDELVKQSRGNRLKESAMRRQDSTVDAPHELESPPPSRQIINARTRVPSSPAAASREGDHSSRYAASKSRNNAPAQFPSLDDFAAQRPEDRAAAMDEWIIANLENPSFTTLCEDLENCWRRIALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7X9</accession>
    <name>A0A9Q8L7X9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756735.1">
        <property type="nucleotide sequence ID" value="XM_047899708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7X9"/>
    <dbReference type="GeneID" id="71980438"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00560"/>
    <dbReference type="OMA" id="PWNSNAG"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="17"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="52292" checksum="8DAC9DE11ED48DBA" modified="2023-09-13" version="1">MSSLGEIQTNLFINGKYVPSSSGETLTIVSPFDDSVVTDKVQVASEKDVDAAVVAAKAAFPSWRSTSGAKRADIMLKFASLLESNIDKLARLESAAMGQPISVAKKFLLGPIALWKYYAGYAGKVAGESFPPDEDGTYKIVQYEPLGVCAGICAWNGSHVLAAWKMAPAMATGNTFILKSSEKSPLALTAYGDLINEAGFPPGVINVLTGAGPVGSLLAYHMDIAKIAFTGSAVAGRKVMEAASKSNLKHVSLELGGKSPALIFDDANLENAVEHSSTSFLRNSGQICFAASRVLVQEGIAPKFIEAIKTAFEKADEKMGDPNLEDTAFGPLADKKQFERVMSFMTGAREEGVQVLVGGERKGDKGTFVRPTIFLNPDLKSKVYTDEIFGPAISLRTFKDEEEAIALANDTTYGLGSTIYTSDIARALRVATQIEAGTVGINSAFATNAQTPFGGFKQSGYGRESGIEGLKEYVQAKTIHINLNVPPPKVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Y8</accession>
    <name>A0A9Q8L7Y8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Translation machinery-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 4">Interacts with the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The SUI1 domain may be involved in RNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DENR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756827.1">
        <property type="nucleotide sequence ID" value="XM_047899243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Y8"/>
    <dbReference type="GeneID" id="71979973"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00095"/>
    <dbReference type="OMA" id="EVFEIDM"/>
    <dbReference type="OrthoDB" id="277199at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005873">
        <property type="entry name" value="DENR_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048517">
        <property type="entry name" value="DENR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01159">
        <property type="entry name" value="DRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21023">
        <property type="entry name" value="DENR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="SUI1" evidence="7">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="22140" checksum="643A9DD77ED79832" modified="2023-09-13" version="1">MADTTTAPAGDLRPAKSVTYCGVCSLPPEYCEYGGTTKKCQEWLEKNQPALYSKLYSDEALSTNLSTLSVDAQKRAEKDAIKKAAKAEAQEKKAAEDRASSKVYIKRVERNKRKYVTEVSGLENFGLDLKKTAKEFGKKFATGSSVTKTASGGEEITIQGDVSDDVVEWLEEHHEEIPEDNIEQIEDKKKKAPGPPLPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8T3</accession>
    <name>A0A9Q8L8T3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757263.1">
        <property type="nucleotide sequence ID" value="XM_047900115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8T3"/>
    <dbReference type="GeneID" id="71980845"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00967"/>
    <dbReference type="OrthoDB" id="10544721at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040456278" evidence="2">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="91" mass="9376" checksum="269F802D208E90FE" modified="2023-09-13" version="1">MKASVITLLGCAAVSVFATPIANARGVAPLGTLPQRRNGGELSTGNLEGDQSADAVENNKVIQRRDGGQLSTGDLEGDRSADALENNNVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L989</accession>
    <name>A0A9Q8L989_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_03401</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757472.1">
        <property type="nucleotide sequence ID" value="XM_047902549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L989"/>
    <dbReference type="GeneID" id="71983279"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03401"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="12">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="185"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="862"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="969"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="990"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO13106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1001" mass="110247" checksum="91CD7D06150977F0" modified="2023-09-13" version="1">MRSHVQILTTPTADTPGTTLLLHFDNKRYLIGSLAEGTQRACVQMGARLLKVSECFLTGRTEWTNTGGLVGMILTLADSSASSQASSWEDALKKVKAKAKRDGIMDGTPEMKQLEEQAKKEASNTLTIFGPPNLNHTLATARRFVFRKGMPVNIHEIRDGDTRTQQEDEWAPFWADDNIKVWAMSISPDNPKGASATPPESASPRKRSLDEAFGEKNGTLTVSEDLTQKERDYLTVKAVVSEMFNSSWRLDTLYETSLADVKQPATVFVRNAQTNKLEKYRGPMPGGKEPVPDLNLKVLVRRPWPGALVESLPHVEPAKEAVSYIIRNHMQRGKFHPERAQELKVPKGRAWAQLSKGESVQNSDGETITTEQVLSPSRVGGGVAVISLPGPEYIDNLISRPEWREPKVMEGVGAVTWICGKDVATDPRLQAFMKEFNNLEHVVSSPDYCPNNIALDSATAATVRLRELDPARYSVPVHDAEDGAPQTYGGTSAYQETQTSKPLPARIAVRGQMVQLEPSIEVQTKDAVPALKIAETAAEVPKEVMEEAIKAQQASKIIDSDMQKWLDSLPPGAQDAQVTTLGTGSALPSKYRNVSATLVRVPGWGNILLDAGENTLGQLRRVFGTDLKQILQDLKILWISHMHADHQLGTTSVIKEWYQQVHGSQPASLADQQAGYAAKAQQQRRLAVVSEPAMLQWLYEYSALEDYGHSRLAPLSVTKKGRDWSGLGWFIPPRELKDLSWEDQRARLDEAVLSPSDLGLADIQAVQVRHCHGARAVSITTPSGFKVSYSGDCRPSKDFVRIGKDSTVCIHEATFDDELQGDAEAKNHSTTSEALDIAQKMRAKACVLTHFSQRYQKVPVLERGNEELPADEEMVTTNDESANPDDNMDAPLADVAEQTLPDQPASEGDTGQQYDLPSKVGAAGEAIRFTLTSDMKVCVAFDYMNVRVGDIGHMEKFTPALLKLFAEEDKSQQADVAEKNSANVVGRKEKEKKKGKSQRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9L0</accession>
    <name>A0A9Q8L9L0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757705.1">
        <property type="nucleotide sequence ID" value="XM_047902693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9L0"/>
    <dbReference type="GeneID" id="71983423"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03545"/>
    <dbReference type="OrthoDB" id="3923202at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="68" mass="6805" checksum="87D786B32569290A" modified="2023-09-13" version="1">MASAAVVGPVNAHLPPTHPKLSEKEAGAICPVTLATLNHHKGKVALHPAVPDDAPAQKCPVAGAQMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAI1</accession>
    <name>A0A9Q8LAI1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ xdj1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_03816</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758162.1">
        <property type="nucleotide sequence ID" value="XM_047902964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAI1"/>
    <dbReference type="GeneID" id="71983694"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03816"/>
    <dbReference type="OMA" id="IVFHIVE"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="147"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="147"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="47496" checksum="309DF215DD93F1E5" modified="2023-09-13" version="1">MAEEIDLYEVLGITSTSTKAEVKKAYHRAALTSHPDKVPEDQREEADIKFKAVSQAYEILIDDEKRAMYDQHGMAAFEKGQNGFPGGGPDLDDILAQMFGQGGMGGMGRDSFGMGGMGGGAGPRRRRGKGKSEMQQYEVTLEELYKGKTTKFASTKNVICSHCSGSGGKSEKVKPKTCDTCKGRGSITKLQPVGPGMVTQATVPCTTCSGKGSWYQDKDKCKKCKGERTIKQKKILELYVPRGSREGEHIVLAGEADQDPDDSEPGDIIFELVEEQHKVFNRAGADLHAELDISLSEALTGFNRVVLKHLDGRGIQLHVEQPEGKVLRPDEVLIVHGEGMPLKRSDTRGDLYLSVKINFPEDGWLKDQKAVDAVKAVLPKAEGIKFGPGETPEMVDEVQFEVIDSLEGFGAGSDDPRAAGAEWEDEDDGAGGAQCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAL5</accession>
    <name>A0A9Q8LAL5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758336.1">
        <property type="nucleotide sequence ID" value="XM_047902533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAL5"/>
    <dbReference type="GeneID" id="71983263"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03385"/>
    <dbReference type="OMA" id="FPYLDAK"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF3">
        <property type="entry name" value="F-BOX PROTEIN POF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="7"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="86"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="757" mass="83687" checksum="2EB060BD1376A449" modified="2023-09-13" version="1">MEEQHQTTKLLDLPIDILLLIFPYLDAPSFLSLTATCRALHSTEILHDSAFWSHLVRRDFRVPNQPVVQNDGHRWQKLYKRLRTQAKIFTWGNNEKGCLGHSYETPMITSPGPGARRGRRRHVNWPVEMQGITKAMGVISDVQCGGWSTTMLTSKGALYMVGVMDGLFFDRRQPPYVQRVQAHPVALKFPDGYPKAGERYEPATALRQFSSGRAHVLALSDSGRIWTWHNADLPGTHVKFVHHETKEDGRERGRGAIKNVVAGWNKSAAYIEGSGIVIWEPLQMSQAECDETDTALVLETAVVPGTKFITSKHAKADDTDAAIGEVQSFIVLEAAIVFNTSLGKVFAAQIIWDDEQQTVKDPIELQMSGKSDDPEFVTDVQGSFQNFAIFTKAGAVLTSNLDTLMPMLQRTNAWMQSSPAGLFRKIPALQNKQVISLAFGDYHIHALHAPGHITSYGYEPQGCGALGLGGSGTPENRLRGIRNQDIGGDGHLVPHAYTEGRQVWFEEEKRQWVRFLTSGGVDQAEAAERIRLAIGSPDVAAQGEVSEWIEQQGRDWESKFNVAGDSDGGLGAYFALSVTAAGWHSGALVLVNETTAQNLSRAVEVPDAPPATNDIDSLPSHEEGPSSSLPPRSAPTPITSQDTSYLGQALDWGRYLLGLPPYNVSAASHGPDQVRADIRLRSQNVTRDAHHNLEPINYGASPRNGYKYVWADDHFPRLRLSNGTEMPGEVGFDEWRYGRPEWKLDWQNDVEQASGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAP2</accession>
    <name>A0A9Q8LAP2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein mL67</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_03670</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL67 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758381.1">
        <property type="nucleotide sequence ID" value="XM_047902818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAP2"/>
    <dbReference type="GeneID" id="71983548"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03670"/>
    <dbReference type="OrthoDB" id="5333655at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024629">
        <property type="entry name" value="Ribosomal_mL67"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184">
        <property type="entry name" value="MITOCHONDRIAL HOMOLOGOUS RECOMBINATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12829">
        <property type="entry name" value="Mhr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="272"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="663" mass="74730" checksum="6467E844215B14A6" modified="2023-09-13" version="1">MSAIQKEIVPHGRFVYAFCNVRTNQVLYSLSRTLDNTALKQLPDLGANHTPPQLRKDLWRPLYSVELPATPHGAKQGIHALRKLREYRKLHELSWEQTAMMTRNMTDKEIEREKKKLEDRGGSKKETVYDIMKRQKHKMKLKMVMDQKANSIADLAAVLTEQEELGATTAEAKQKHADEWRTRSLEEMERLAQEADNGSIEKIETQIEELCKTLQELRQHGTEGRRGKLKKQIVVTRQQLQKMRRAAQVAKEVPPASLEIERLAQEVKNGGLETLSNQIAERRGRPKERKNSAEVEEPTAEAEESFEEAEQRHERMQWAAKAVEEAKANPAYIEGAATEAADAADTAEAALAASAVEAASARETASAAEAKAESASEAASAEKAALAKEAAREVAVARDAAVAREAALARDAALARETASAREAASSEQLLPAYKRAKMLWYAEKFDPIKRDPEYLPKRGWVRREAERWNRPVYTSKGITVKWANITDAEYAASWPDAVQHERMGYTTRSPPLVDTETVAEFRALSWKGRRENFQLDETTAEKVERLRAEMGLQARVDKPWKFVEAQEIESGFLPGRDPSDVEAAEVEGEELEAAPEVAEEFVEEEDPERLQKIQEEILGRVRQMASKESWDKRANQDLKKAKNKFKLAPLPVDATVDQQPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAS0</accession>
    <name>A0A9Q8LAS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02732</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758298.1">
        <property type="nucleotide sequence ID" value="XM_047901880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAS0"/>
    <dbReference type="GeneID" id="71982610"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02732"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF17">
        <property type="entry name" value="NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="19"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="48892" checksum="8174F0F7C1F10094" modified="2023-09-13" version="1">MLTQDNGVTKHIYPDDREHIVIIGTGWAGYNVSQNLSDKKFNITVISPEDTSPYTPLLASAACGLFDFSLAEEPIRHKSKNITYYKGIVEAVDFDKKFSRCLSTCDIDGVTEKRHFNVAYDKLVLAPGCVTNTFHTPGADEHAFFVKNVNDAKRVQFRLKQLLELASLPDTTEEKQRELLHIIVVGGGPTGVEISAEMSDLFNDDMSRLYPHLNGKMTITIHDAAPFILGAFENALREHAISSFSKRGVTVKPDSKIKKVEADSITTEADGRIGCGMVLWTAGNKQCPLVDALDVCKTDKLPRILTDQHLHVLRPSGSYEQDKTPLPDVYALGDAADIKKYFLPTTAEVAVQKAEYLASVLNRGADGRRVFEYKQKALVAYIGGHDGVVAGRPDWNGARAWTAWRSKNLLWTRSWRRKTMIMIYWALDWMGGKEIARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB16</accession>
    <name>A0A9Q8LB16_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758499.1">
        <property type="nucleotide sequence ID" value="XM_047902823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB16"/>
    <dbReference type="GeneID" id="71983553"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03675"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="272" mass="31420" checksum="2181E1FBF50EB93D" modified="2023-09-13" version="1">MTLPRKVEDMDVAEYIASQSRDAFSDFNLVPIAITEGSLKGQVVVQVKRKTPFRFLDLPAELRNRVYELLLVKAQPIVLWSSGQPRKVYPSKHERLDVKFQDDPPETTALLRANRQIRGEATPILYGMNTFEPVDPETAAVFLEEIGASRRYLTAFDFTWTFELPMAFKACDALILPNIKHVAIHPYDVYRFWTDECDEDHWDCGAEMAQKLKKFLLHVKSISEHPVDPEKVLDVMVLERHRGNFTSNEIAEQAQKCMDMFRKVARTYLDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBQ1</accession>
    <name>A0A9Q8LBQ1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phenylacetaldoxime dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03618</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758844.1">
        <property type="nucleotide sequence ID" value="XM_047902766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBQ1"/>
    <dbReference type="GeneID" id="71983496"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03618"/>
    <dbReference type="OrthoDB" id="3359285at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025702">
        <property type="entry name" value="OXD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13816">
        <property type="entry name" value="Dehydratase_hem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="361" mass="41208" checksum="ACE525DE77496025" modified="2023-09-13" version="1">MGSVEVLESAIPEHLRVERTIPANTPANYQPPFPAYSARFPKDAQGMVTAMIGVQHKNAVQGQSTEFKQISSFVEKPSNGVKPRYWEAASVKDNRGYYNEVAIPYWRSKEDFDQWRSESGFESWWKALQTDGEVGYFLEVFLPSIDRFETVLSDNNEPEGVANMRVGVSGMLQEHVYWGSMRDRLAASQTDHLTGEKATIRPAGGREDTTKRRIHVEGRQNSAMIRSGQDWSNTNPHERKLYLDTMHPVLIKGMDFLRDRGEEVGCIECRFMDVIQKDEAVASPTDKTFGLAYFDDLSSLEDWSKRHKTHLDIFGRFLQYAGELQGNVSLRLFHEVMVVKLEQQYFEYVGCHDSTGMLVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBQ4</accession>
    <name>A0A9Q8LBQ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General alpha-glucoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_03121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758906.1">
        <property type="nucleotide sequence ID" value="XM_047902269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBQ4"/>
    <dbReference type="GeneID" id="71982999"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03121"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF57">
        <property type="entry name" value="MALTOSE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="63"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="535" mass="59268" checksum="57438C8CB61C87BD" modified="2023-09-13" version="1">MAELRTDSPEDRVSVHDLKEKDVYHSEVLVDKDLMNDAFQGENEEHEQSMWQAVKTHKMACFWAFVFCFTIVMESFQMFLSGNFVALPYFKEVYGVQLENGEMAIESKWQSALFAAGQCGAFVGVFIAGPITTKIGYRWTTIIGLILMNATIFVSFFANSLVLLTVGQLLEGVPWGFFIANAPAYASEVVPLALRGACTGTLQMSWSIGGLLVAGVTYAYNQRLDEWAWRAPLALQWLFPTPILVLVFFAPESPWWLMRKGRKEQALRSLQRLGRKSDGNAENALAMIERTVEIEAHLGGNPSILDLFKGVDLRRTMIICLIYASQNLAGNLIANQAVFFFTQAGIDTDFSFQLGIINSALGLVANIGSWGLTAWFGRRTIYLWGTAINVTLLVLLGVCASIAQTTATNYAQAVLGVLISFVFAGFMGPISYTVIAETSSVQLRALSTGVGRGAYYLIEIPCIFLASEMLNPTGWGLAGKCGYIWGGTALFCWVVAYFGLPEMKHRSYRELDILFKRKVPARKFKGTVIDVKDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCH0</accession>
    <name>A0A9Q8LCH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_08523</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759227.1">
        <property type="nucleotide sequence ID" value="XM_047907671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCH0"/>
    <dbReference type="GeneID" id="71988401"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08523"/>
    <dbReference type="OMA" id="EWDVYKA"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000005">
        <property type="entry name" value="Autophagy protein Apg6, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="159"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="290"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="203"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="493" mass="54750" checksum="EAACEB2CD79B9C97" modified="2023-09-13" version="1">MSSTGPALRCQKCKTTLHIDGSLDSLNPASFKILADAAPALEPKAPEAPRSAAAKERRQLYNDVSKQAGPPMHKRTVTANQGTPSGKQYPDMSYINISDSQVVPASQHDAFTSPTRKKSVTKNSDSLNTANGETRMSREMESVMRLFEILSARSDIDHPVCSECTEILLEGLQRRQAGISRERDAYVDFLKKAQQDVPTDEEKAKTKRDLEDARQREKQALQELEALEAEKARMEDEIAALDAEAGELDEEEDQFWRERNAFAAELSAFQEERDSLQNQLAHDNKVLEALQRTNVYNDTFCIGHDGTFGTINGLRLGRTPEISVDWPEINAAWGQTLLLLTVVIEKLGLQLKGYELVPIGSTSKVTRLEYPQIASTTDTKPKKTIFELFSSGDLPLGLGFLHRNFDNAMVAFLECLRQIGEHVEHTTPKSGSPGLKMPYVIAKDKIGEVSIKLGSFGQEEQWTKACKYTLTCCKFLLAHASHVADAAYTKTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCX6</accession>
    <name>A0A9Q8LCX6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sexual differentiation process protein isp4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759474.1">
        <property type="nucleotide sequence ID" value="XM_047907325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCX6"/>
    <dbReference type="GeneID" id="71988055"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08177"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="510"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="702"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="738"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="803" mass="90167" checksum="8F1F084123CA25F9" modified="2023-09-13" version="1">MRLPFTTKAEDKIEHGALEVIEGEAVQDKNDVAVQTQIISEAKAIDKTHHFDPNLSEDVVEALQEAARNNSIEKAIEVEKTFLEDSPYESVRAAVRNTDGDEVANTLRAWILGFLFVTVAAAINMFLSMRSPAITIPTVVIMLLVYPVGCLWARVMPSRTFKTFGVTWSLNTGPFTIKEHSVVTLMANVTYGYAYSTDALLALDAKPLYHLHLGWGFQLLFTLSSQLIGIAISGMFRRFLVWPAALIWPANFSMTSLLYALHDRKRMDPSVTNGWKISGYRYFAYVSIASFVHYWFPGVIWQGLSVFSFPTWIAPNNVVVNQLFGGFTGLSLIPLTFDWTYVMAYLSDPLLSPTFSHLNTLVGLIIFVMISTIGISYSGALFSEYLPINTSTTFDNTQNKYNVTQIMGDNFTFDLQKYKDYSPLFLAPTFALNYGLSFAALTAGLVHTGIFHGKEVWYRLKAARNQEPDIHMRLMAKYREAPDWWYLVLFVVSVFLGLGTILGYSSQLPWWTYFVSIGLALVFVIPCCMILGITNIMLSLNVLSPFLAGFMIPGRPVGVMIFKVYSTIVLGQAQTYTQDLKFAQYMKIAPRTTFACQVAATCWAAIVQIATMNWTLGTIEGVCEFEQKNHFTCPNGRTFFSSSIVWGLIGPKRMFGPGSLYSSFNYFWLVGALLPVAFYVLLRTFPSKKLRWLHAPVMLGAMSWLPPATPLSFSSWAIAGLIFNYWIRKRFYGWWSHYNYLTAAALDCGLLISTIVIFLAITLPGATVPQWWGNTTVFETMDYLGTAVRRTVGVGEKFGPATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD32</accession>
    <name>A0A9Q8LD32_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759598.1">
        <property type="nucleotide sequence ID" value="XM_047907370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD32"/>
    <dbReference type="GeneID" id="71988100"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08222"/>
    <dbReference type="OMA" id="LTHILWN"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459:SF1">
        <property type="entry name" value="FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459">
        <property type="entry name" value="ORF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="140"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="50870" checksum="351A86E24A18E431" modified="2023-09-13" version="1">MGIKPPEGEGLLPPNPYLTHADHIVLDSLYKDIRQGTKNSKQGQNHDQAALDHLRALNNPSHPKFEPTVLSMYDRKDIPPWINRFILDPYGRVATKIVRHPTDVVFLTHILWNTLIALPSAVYLFYNFTYVHAVAHAVHAVWCAGPFTLMMHNHIHNHGILAKSWKMFDSTFPYVLEPLLGHTWDTYYYHHVKHHHVEANGPEDLSSTIRYQRDELLHFMHYEGRFLFLVWYDLPQYFIKKNQPLLALKTFASEISSYIFLYSMARLSGKASIFVFFIPLFFMRLALMIGNWGQHALVDEVEPDHDLRSSITLIDVPSNRFCFNDGYHTSHHLHPLRHWREQPIHFMQQKELYANERALVFHDIDFFMMTIRLLCKDYATLADHLVPMGDQANMTKAEIAAMLKSKTRRFTEEEIRQKFRKKGLSSQAQVVKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDW9</accession>
    <name>A0A9Q8LDW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759961.1">
        <property type="nucleotide sequence ID" value="XM_047907566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDW9"/>
    <dbReference type="GeneID" id="71988296"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08418"/>
    <dbReference type="OrthoDB" id="3650885at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="24467" checksum="CAC95E748EF45C57" modified="2023-09-13" version="1">MDKSPLGSLAPELRNRIYELVLAQDQPVYIIQTSRAYGKYKQDPHRSRRLEIAITQTCRLLRQESTKMFYGFNLFTFAGPGQTAFGNPLNVALGFLESIGEVNAFAVREIHIESHRRTPVYAGPPHPRSEESAEEAKNQLDIASRGADRICQMAPACHVLVDLSFHAGALSFHLPTRSASMERYIKEVLALFVEMAPGVWPSGAVTVTQQIIDAQWNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE22</accession>
    <name>A0A9Q8LE22_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD repeat-containing protein slp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_04371</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760108.1">
        <property type="nucleotide sequence ID" value="XM_047903519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE22"/>
    <dbReference type="GeneID" id="71984249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04371"/>
    <dbReference type="OMA" id="PVKSHHG"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000098">
        <property type="entry name" value="WD repeat-containing protein slp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="294"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="346"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO15742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="615" mass="66091" checksum="2A685D5A491028E9" modified="2023-09-13" version="1">MATASVLTPIKSRRDGIFSSRLAGGRMPLSPSPSTPKTAAIEPTESIHHGNVNLMSRFSRSVSKTNVRDSPKSNIASRHPQSPRRLDTFDSDFTLTGTGPRPSTATSAKNTPSRSKSGRSTSVHRTPKRSQGKINYTAADRFIPNRDASEAISSQGAAVKLDGERTPGRRPKSIASDGSAALAASVSSAFDLGRSSTSDATASLSLEGLNLNDEDDDDEEPKTKPSPNTVAYQHSVAEACGVSMKQRILAFKPAAPESSRPIDLRSQYNRPLKPTAASASQFRRRVLTAPERVLDAPGLVDDYYLNLLDWSSGNQVAIGLERDVYVWSAESGSVSSLLQCPEDTYIASVKWSGDGAYVAAGLGTGEVQIWDVEEGTKLRSMYGHDTRVSVMGWNKHLLSTGARSGLVYNHDVRIAQHKVAELVSHTSEVCGLEWRADGAQLATGGNDNLVTIWDARALNAPKFQKTNHKAAIKALAWCPWQSNLLATGGGSHDRMIHFWNTTSGARTNSIDTGSQVTSLRWSTAYKELVSSSGFPDNSLSIWSYPTLVKNIEIPAHESRVLHSALSPDGQMLATAAADESLKFWKVFEKKPGQASLIGGGSTTAKAGLTKATTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEA3</accession>
    <name>A0A9Q8LEA3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760005.1">
        <property type="nucleotide sequence ID" value="XM_047907929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEA3"/>
    <dbReference type="GeneID" id="71988659"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08781"/>
    <dbReference type="OMA" id="MVWIDCC"/>
    <dbReference type="OrthoDB" id="3636603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13324" checksum="C411D19516EA9629" modified="2023-09-13" version="1">MPSKRSAESTPQRGSKRLKEHTPEAKRARLYQAVDASRKEIRLLVVAAGAKDDPVRGTFRHVSLLDDPKPVFETISYVWGDPKLRATMFLHGLLIGIPKSSERVLRRMRHRHCQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEJ2</accession>
    <name>A0A9Q8LEJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1479-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760437.1">
        <property type="nucleotide sequence ID" value="XM_047903712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEJ2"/>
    <dbReference type="GeneID" id="71984442"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04564"/>
    <dbReference type="OMA" id="ISEKWHP"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="56781" checksum="369E466DB6EAB9C7" modified="2023-09-13" version="1">MATVLRPSLRAGRRVLQTPSKQQQQARNAANASAQKRQGDISDAFASLSGIQFTELDPRFADLKAQLIAGKEDALYDSWNRLLASLREEIPLIAQRGPDIVPQIDFKDIDNAGEEFKAEHRKRGVAVIRNVVPEQEALNMKTELRAYLEANPHTKAFPADNPQVYELYWSPSQINARSHPNLIKAQRFLMEFWHSKDPSALISSSHPMIYADRLRMRMPGDAQFALGPHVDGGSCERWEPDGYGKGKVYESICNGQWESYDPWESSCRLPVVSDLYNGVGACSMFRMFQGWLSLSNTGPFEGTLLVNPLLSRATAYFLLRPFFSPKQPAQDPTAETYEEAFLAPQNWEIQRSPDAWLQGATPGHGQELRPQLHPHLNLPSSMVHVPRVNPGDYVSWHCDTIHAVDSVHAGKGDSSVMYIPACPLTVSNAEFVARQRQAFLEGTPSPDFGGGKGESEHLGRPGVQDVEKVNPVEGMRAFGLKEWDNSEPDLTEGQKKVMDRANKVLGFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEY9</accession>
    <name>A0A9Q8LEY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">26S proteasome subunit rpt4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_04702</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760539.1">
        <property type="nucleotide sequence ID" value="XM_047903850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEY9"/>
    <dbReference type="GeneID" id="71984580"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04702"/>
    <dbReference type="OMA" id="DHEPCVI"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="7 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="167"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO16173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="390" mass="43786" checksum="6B1D6C4B400EEB67" modified="2023-09-13" version="1">MSDPERDHALEEYKNKLLDSREWEAKLKALRLEIKCLQHDFDVSEDNIKALQSVGQIIGEVLKQLDEERFIVKASSGPRYVVGCRSKVDKVKLKQGTRVALDMTTLTIMRMLPREVDPLVYNMSLEDPGQVSFGGIGGLNDQIRELREVIELPLKNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAVASSLETNFLKVVSSAIVDKYIGESARLIREMFGYAKEHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDYLGKTKIIMATNRPDTLDPALLRAGRLDRKIEIPLPNEAGRLEVLKIHAESVQKEGEIDFESVVKMSDGLNGADLRNVVTEAGLFAIKDYRESVSQDDFNKAVRKVAESKKLEGKLEYQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFF9</accession>
    <name>A0A9Q8LFF9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small ubiquitin-related modifier 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760049.1">
        <property type="nucleotide sequence ID" value="XM_047903953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFF9"/>
    <dbReference type="GeneID" id="71984683"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04805"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="71"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16246" checksum="8F5DAD49DE0BB966" modified="2023-09-13" version="1">MSIKSIIQVPLGDDFVECSVSLPATIGSARISQFTSRVSAAVFEIASDIDEGSATPSSSNRSHSRAESNIVSIQLRGADGFTVWFKVKRQATLYRVMETYGRQAGVRITRLNFVFEGQRIHHSYSADTLDMEDGDTIDVYRIRESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFH7</accession>
    <name>A0A9Q8LFH7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760832.1">
        <property type="nucleotide sequence ID" value="XM_047904166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFH7"/>
    <dbReference type="GeneID" id="71984896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05018"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="480" mass="52190" checksum="9C38DABD895B61EC" modified="2023-09-13" version="1">MLQLVSPKRRSRWSAAHSSPYEMGGPPGARSGNRRRAYPHNWELRDPARYGDRFVEELESEDDDGQGVTLDPNVHALRDARQRGFRGDELYFDGYDLGPDRTTRRGVYDDAYYDDCISEEEEYLQQQGSRYQAPVRDKQDLLLQTALDRIARAKEKGKTNVNLSREEMDALSAGRGQQLEPSSSLASPPVTPAKPSKIKASSRQSSTGSLTGQKTRKKSTSGFFGSPAKSTSSKAKIPRKNSIEHAPSYPSAPPGIMVPGPDGRPVWTPISYGPPSPELQRAQPVGSRSSSKHSRRESTPPEQLPPFASRYPGMRPESSGSNRSMPDDVDWYPPPSRTRSASNAQYGRHPPSDDYDMAPPMPAAQGRRNVSGPPDVRYANLRRQPASGSPLAPRAQPAGRASPVAARMSSGSHGSALRRVETSSSDSSEGAGVQVDVVPEDNGGYAVRQTSGASPPVERTSSGTPTRGGAEARRRKSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFK8</accession>
    <name>A0A9Q8LFK8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Interferon-related developmental regulator N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IFRD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760869.1">
        <property type="nucleotide sequence ID" value="XM_047903532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFK8"/>
    <dbReference type="GeneID" id="71984262"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04384"/>
    <dbReference type="OMA" id="HISGRHI"/>
    <dbReference type="OrthoDB" id="18978at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039777">
        <property type="entry name" value="IFRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007701">
        <property type="entry name" value="Interferon-rel_develop_reg_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354:SF1">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05004">
        <property type="entry name" value="IFRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon-related developmental regulator N-terminal" evidence="3">
        <location>
            <begin position="63"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO16503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="48604" checksum="E561ACC18878E71A" modified="2023-09-13" version="1">MHDLRKQVLLESKKTTSRKARSKDTSPPLSGNGSATASPRGSRVVSRAPSDDESEVSDGTEATSHSVDALGDAENEVEDDTWITSLEQRIEALVDRKRSSTEGREEMIKSIIAILRKHFAEAELRRKMDELLPALLKSVKSGQSEDEIVLALKTLALIVITEPSDAIFDALEGPIKHIMNDSEYPGAKVAAIRALGMVTFYGGASEEGTLEVMELYLDIISSDGAVIDETDNGKVVVAALEEWGFLATQIEDIQESNEAAMEIFADQLESSDVAVQIAAGENIALLYEKSYTEAESGDEPKDDDGSDGDGIRMVKRYDVYRQSRKLEQTLERMVKDSCKSIAKKDRKQLHVAFRDILSTVEKPTRGPRYSTATDMEDREYGSRMKVTIPGGGKMVINKWWKLHRLNRIKGLLQNGFMVHYQLNQTIFDSLPVMVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFX2</accession>
    <name>A0A9Q8LFX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Carboxypeptidase S1 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04487</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761083.1">
        <property type="nucleotide sequence ID" value="XM_047903635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFX2"/>
    <dbReference type="GeneID" id="71984365"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04487"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF189">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040314607" evidence="8">
        <location>
            <begin position="20"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1032"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1052" mass="117670" checksum="2C72A39A7720A79B" modified="2023-09-13" version="1">MATFLLCTVLGAFATPTSASFPPPLVGVTTIPVPGQPDTSISYKETTICETEAKGYAGYVHLPASRLHDVGLVEPYNISTFFWYFEAREDPQIAPTAIYLAGGPGQSSMYGVTESGGPCTIHPDANSTQYNPYAFNKHVNMLYIDQPVGTGFSYDSLLNSTQDLLANTIASFDSYDESIPAENTTFLYGTFPSQDPTRTISTSQTAAKILWRFAQAWFTSFPEYTTSDKRVSLWGNSYGGYWVPATAAYIVEQNEKIKTSQLPDAYQIEIDTIGWTNGCPDVLVQGEYWPEMAYNNTYDFQAVSFDVYQDMKDSWTMPGGCRDLVEQCRTLGNDLDPDFYGTDHQVNAACIHAFGFCFGTVAQDPGNRSVFDIAHTNPDPFPYSYLIGFFNRAWVQQHLGVPVNFTGSSNSVFDNFFITGDFVRYEGLKTISALLNSGTKVAMIYGDRDYRCPWLGGEQLALQANWTDTDAFQKSGYETIKTSSCYNGGVVRQYGNLSFSRVFQAGHDAAAYQPRTVFEIFNRAMFDKDIATGTSPTNDERNDYASTGPLSSFGIRNKMPEPPPVNCHLYNVPLSCTTEQQEALANGTAVIQDFNVIKPDGGSAGVLGGNMVFLLYSDDRIGSAWERRSLRGDSERSAVLFLRRMRLELKGLKRAIRQVKSLENFELVIDEDDWYVLPLEIDQVKKMEDELKQALAGQTTKSCRGAFFSPFVRAHVPELERQGINQATFLAFIDGLNEAFVANPVMQYTGMAGAVMSQFHGLPPVQWAGMGLQTASGVASFATSHRRTKAYVKAVNIDLFHPADLHVTIMTTPEMMAKVGQPDIKLRLGSLEAFDSTIDTAAKPKQDAKVAHADSTEDDFRMRRIQALQGYIMPLDFNVPGAVAPENLLCRMGASQATRMASKQHKKMIKECTKGHEDYLKKLKDSDEKWQEGTKEAEKIERKLAKEKEKVERRIVASKDSEKARRSFEKEEWKLLKDLEKEMNKREKDAGKERREAHKERIEAHQEREKVEGREDKTGNKIGWIVVSRWDGEEDGRSEDMDGMVDQEQART</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG64</accession>
    <name>A0A9Q8LG64_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761192.1">
        <property type="nucleotide sequence ID" value="XM_047904494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LG64"/>
    <dbReference type="GeneID" id="71985224"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05346"/>
    <dbReference type="OrthoDB" id="3640263at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="1">
        <location>
            <begin position="11"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="376" mass="42396" checksum="7CB01A1F3531C53F" modified="2023-09-13" version="1">MADSTFSSRYRKYKQDTHRLIRWLYSIGRTFVQPLGTTLSVKDLLTLAHCICSAVPIIDIPLEIEYAVRDAIAGRVEASRSYASLLQSCQASTLLAEQNARHEHFIRVLRQILQFIQEARSRLKIECNARKIDDKGKYVDPRAAADILRSLDLEAGRSEECDDGGLPDYDDRDLKLDRDDGDFLFELWTFLQDQRDLREHVRKVWDRYHKCNITFAVATRVTESAFGIIREMCDAFTLSSYEQLTACLGLALFSSSTGPMFFTLATDATGSRCNSIWTQSWQASFSEHPFAQALDAVAESVSALAIKGSPGDDAIDGVFLDEFTRALVVFKQKQIIPMSAAFQAQIYMDFFEALGGDAGLPLLAPRRTHEIMDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGD1</accession>
    <name>A0A9Q8LGD1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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            <strain evidence="1">Race5_Kim</strain>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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        </source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="molecule type" value="Genomic_DNA"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
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        </citation>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
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            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO17298.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="116" mass="12479" checksum="7F768D30A4FAEC75" modified="2023-09-13" version="1">MDKRPHAAEENVLAPIKGAKSTAKTQDETRLQLQRTVSGPPYTIFTPRAKLFIIIAVSISSLISPFGATTFYPALDTIANDYGVTPTLINLSLTTYMIVQAIAPALIAGMSDQNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH83</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047903370.1"/>
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    <dbReference type="GeneID" id="71984100"/>
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            <end position="499"/>
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        <location>
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            <end position="566"/>
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        </location>
    </feature>
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        <location>
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            <end position="792"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1108"/>
        </location>
    </feature>
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        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="126"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1218" mass="136662" checksum="A335E941CC94C375" modified="2023-09-13" version="1">MDRPVQSVHAAQFEQRLKDPVIEEVHDDPPTNAIPGSFPDTNDTNEGTLPMTNDNNEKDTNDTTTPQLQQHQLVHSSSGLPPTPPTMTNSDIAESQPERVASPAPLFADRVRNALQSHKSGLSTPVNDLGNHSPPTPEASPRRKEKENLAVPRPPLTHYPSSYADSFKTATEGLSANGSSSRVHSPEQDFTSEQHKTWWERTKPFPQAAIGLGLDLQREDISKPQSDESGKSIGSHRPMERNLASPQRNYEPERLRKLRDAPEPFPDFDQNLTEDSEAGEARKKNYPVSSPETNGDSEWLSSINPRVIEAALQPEPSPKINPAPLEAALQSHPSPERWPRSSPVKKSWLSSKTAVWDNADTFSGYAKSDDSPDDYDPSLAPYLAAYDSQLATAWRTEDSDRSEVRVKNYQMESDSDRDRTRPSSSDGPPSPSWRKPLHHRAAVHKLRKPIQPGDDLKRPDEVLLYGSSVPWKRAKVEEAKPRTEPRQPTPPRREMDSEFLRTGNVLPTRRPVLREDVLSEQSQEGIVEDPQTPDNEHESDMAEPPSKLRHFRPDVLSPPASAGMSVPTRKLREFTPSVPPAEIDSPPNTAAKESLVNNNRVYKVIQENNAKRHSVVSEGSAVQATLIFPAEGQRRQLRHSSKRESLRAGISIASLSKANSEESMHTPRLRHKRAMDSIGSSDAPGAPTPERFERRIQTEPINSSCARLTPVAVDDITHGTMRPQRISAMPGAVNGGIIRPPKLRRTLRDQTLHRHSVSFDVDHEAEIPESTPSPRLRRFSEEERLENNREVRRTSLGRESQLISHDMDLKLERLASDLTSVGREMPDRSSIKDRRTSSESKNPTSPRRKSFDPRLLNPIGTPLSTSLSERTAITEAEYGLARGIEIHQHNNDSLLLIHGRSLDYDQANPLSEEPLPSIEHDYDTQAGAQYPTFHAFVESPAQNHADDIIGISKHHVDSPLTNPREAPMPPVIQFIPPTPSEELERTLSGALEQQDLKPGLKRGLSWSQKAKRFSENLVQPLPFGRGGSLRRPRRVVTETEADKKPRPHSLSPMWTPRPMDDLHTDSEDDDDYDDDDDDDDRLPPGGDTSDIPDHNDPKRKSIFPRNMSVRMPGFRGNGGFLVGNSLGLDRHGTNDRRHYVARRPSRESLRRAKQQRRRTFTLPFTGGKRVEYVGLAGLQEHLQTSKQRKEERAAEKRREVLRGQIVTRVYHEGRVAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHP5</accession>
    <name>A0A9Q8LHP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Autophagy-related protein 33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06467</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762207.1">
        <property type="nucleotide sequence ID" value="XM_047905615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHP5"/>
    <dbReference type="GeneID" id="71986345"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06467"/>
    <dbReference type="OrthoDB" id="5336366at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051668">
        <property type="entry name" value="ATG33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="16593" checksum="8770AD63D84CD6E3" modified="2023-09-13" version="1">MPSTIGTFKIIGVLGLGLLTGTSYTLSTLSLPALLTLPSARPASYTLSQTTRLTTLHTRALSTISATSLFLAFYLSPSHLRHPYLLWTGAVAGLSGGLNLLMDARDKKAVAIEDVEDVNGEQVERRARSAQMVEFVRTGVAGLGFVMGVIGVWGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ4</accession>
    <name>A0A9Q8LHQ4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04751</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761204.1">
        <property type="nucleotide sequence ID" value="XM_047903899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHQ4"/>
    <dbReference type="GeneID" id="71984629"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04751"/>
    <dbReference type="OrthoDB" id="4348522at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="18245" checksum="B9091713A9AAB3F3" modified="2023-09-13" version="1">MAESMKCALCGEDMKSSTRLPCHHFLCDGCANRYLATSNTCPTCNTLVYERSTAPTLQSFNSPTTFPPNLYPVPAGLPLYMRPGASFGGMTIADPIPERPSKLSNQQVDNYRADPVLTSQGGSQHNAPAGDSPMQQSGPSKDTAAQVARNPDQGVEKGDQLTKKYTGGGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI86</accession>
    <name>A0A9Q8LI86_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-binding monooxygenase ktnD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05844</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761985.1">
        <property type="nucleotide sequence ID" value="XM_047904992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI86"/>
    <dbReference type="GeneID" id="71985722"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05844"/>
    <dbReference type="OMA" id="WNTGGCT"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="551"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="581" mass="65648" checksum="250E8097BD14C13A" modified="2023-09-13" version="1">MAGDLAWPEVPIGNKNHANAAVVIIGGGISGMCVAIDLLKRNKCRNFIILEKSAGLGGTWNDNKYPGCCCDVWSQLYSYSFAQNPDWTREYPGQEEILAYLQRVAQEYKLLQHFRFNTEVKDATWDESEKKWRVNVKTASGSKEAEYNPEYEIKTDFLVSAVGQLNVPQWPEIEGIEKFEGKKMHSARWDWSYDVTGKKIALVGNGCTAVQILPELAKVADHVTVFQRTPNWVVPRADAPVSATWRNIYKYVPGVMARKRAALMDFREWTHGFVADANSDTSKLFAQMSKQMLEEQLPNRPDLHEKLTPKYQLGCKRIIISDDYFPAIGQDNVTLETRPISSIDGHAVKVHDPNGYPVPAREDYDLLVCATGFKTVDFMHPIKLTGKNNLPIGEVWKDGAQAFYGITVSEMPNFAMLYGPNTNLGHNSIILMIEAQSRYINGLISPVLDARKNGRAISITPRNEPMEAYNAMIQKELQNSTFNDPNCQSWYKNEKGIITNNWSRTVVEYQKMVEDVKFEEYTVEGDGKEEVQRKQIHVGRVKEETAVSDRALMVMGALGTAALVGGWVLRNTRYLQSVRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIR5</accession>
    <name>A0A9Q8LIR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762611.1">
        <property type="nucleotide sequence ID" value="XM_047905319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIR5"/>
    <dbReference type="GeneID" id="71986049"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06171"/>
    <dbReference type="OrthoDB" id="3797974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="84"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO18245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="380" mass="40727" checksum="9BDABDF5596D9758" modified="2023-09-13" version="1">MAQNATENSSDEFLVFPSFQPDVAFLKKLERRAPIDKDPTRGPQLKMIPATPPDGSPPATDVPFDPNTDELYRLDDSSGVNQWIYIINTGFDTSIPDLQANGREVTTFVVPPSFTLSESIPIDRRGPTDISDIGDRDASTNTFRGHGTGVASAAGGLEYGVTPRANLHLIKGKGSFCQPRGEGLTSHVAAGYTHQAIERAFGHIQGHYFGLRTNNGVTRAVINLSWGIARQDGAREVNRDSELGRLFDKFLSWAVDNDIVVVCAAGNFGRSAEQQVLGDFLPQRLASAGNNALITVGAVTGQGALWDQTTPPGPSRRDYGEPTLTGQHDIFAMGDNTIRYQGLGGQEKGSGEGEFGTSIAAPQVAATIAYLFQHPVNGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJL2</accession>
    <name>A0A9Q8LJL2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator-type transporter ecdD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762209.1">
        <property type="nucleotide sequence ID" value="XM_047905612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJL2"/>
    <dbReference type="GeneID" id="71986342"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06464"/>
    <dbReference type="OMA" id="CEIAPAH"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF11">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER (HXT8), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="11"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="494" mass="54345" checksum="7E0069A4AA75A924" modified="2023-09-13" version="1">MAKVNWYMWKLAIFVAIGTFLYGYDSGIVTITIAKPSWINYMGRPSPNYIGAVASVYSAGQALGCLFQVFVGDHISRIRFLQAMAMLEAAGVIVQAAATSMPMFIAGRAIAGFPTGALYLTTTIYLVEISPSQTRGLVAGCGGLCIGFGIMVSSWIGYGASHLPYGTLQWRLPIALQALWAVILVVGLALHVPELPRFLMFNGRLDEARDVYFKLRPDLSAYRAEKDVSWLRAQVEFERTRQQDQSISELFRLHRKRIGVAFTAGVISSLTGAQVIGYYQIQLYQQLGIELKHRLLLAGVYGTVCFLAVMTTDNFVIDVWGRRNLILFGLIGCVLAQIYSAIMHWQFEFTTNQVGKGFAVGGIYLLTAVHYAAFGSTAGIYQAEVLPVAIRSKMMGLTGFASFCIMTGLSEAAPVAFVTIRQNFYSVFVGATTVCLVIAALWFPETKHKRLEEIAAVFDDTVLTVPESWQKELVRGEARRKRILSCCSGGDVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2T3</accession>
    <name>A0A9Q8P2T3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tachykinin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2T3"/>
    <dbReference type="GeneID" id="71982148"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02270"/>
    <dbReference type="OMA" id="VMQIVNH"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="56081" checksum="622D51E54744CB5A" modified="2023-09-13" version="1">MKKTKGTSVRKDESTEESNSNAPPTRPTSFEFVSFGDASQPRDPGARSKIRRHAMKDIGYRRRKPKKQRYLNISLDIPADVETLQSLRATSPQAAIGGGGVHTFFKFPVDLDDIGKALVANMWRDIGDCLQTAHRRDWWPVGIADEATFYQILANSELHLEGTRNPHRLSKETPLSIHYHQIAISSVRKRLAANPDDVSDGLIGCISGFLVYPEIAGVFDRWLPQRKGILEAIGTREGGLDSLEKHLRRSISWVELRGSFTQDIPSIIPLPQYWIDVHRIESADNASMPACFSIDLQHAWQQHFPNDTAFLHIFTSLAELNTRASLNKQGLRKEDFFYDGIVVSANVLTHELFCLRPAEDASLGINSRRILEACRLALLVFIAAVYKQYGAHPLKAVVHLGKLRELLSQSDVEWDGLEYVQMWVIAMGAMEAYDEGMREWFVGELVRVIKERELDVDEVMRGVTSVLWVAELFEQKGGMLRGWIEQRQYIPFQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P341</accession>
    <name>A0A9Q8P341_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P341"/>
    <dbReference type="GeneID" id="71980129"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00251"/>
    <dbReference type="OMA" id="TEYRGCI"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040172266" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="126" mass="13030" checksum="AB6F7E25EC10F057" modified="2023-09-13" version="1">MFSLTTTTILLATLTSLTLAAPTAQAPPSYSSPPAPQPLGISLSTDAHCSTLTSSTPTSLVNGTCYPVPSGFASMEVYAPPIHGLLTVFATGECVVGNDTQYFSTEYRGCMGLKGEGRGIMYTAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3G0</accession>
    <name>A0A9Q8P3G0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein EFR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047901035.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981765"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01887"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="250"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="658"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="731" mass="81065" checksum="1DB97531FB1E7359" modified="2023-09-13" version="1">MPTTHLPGHLDSLRQKARPKHQLLVLKCYPRLPKNSTADVKPNSSELSYLLYYASTRQDKLTKVGTFLEQKTAHDVYRYQSTRVLVTLQILTALLEHKEISRASGFALIAPSVLRILRDIINNTNDISLIEATAATWHVFCQHQDVANLAADSEYRTLYEEVVRLYGSLAKNHSHKLGKSTQPVAHHDAIRLRKTGAEAVKSIFGMSELNRNWNREYHAAIAAVLTNLRCDSEHKDGTNEYLQHLVAMSTKNEEEDRPSTVNRRQSIATVRTFSGLPDEQDPDPRTAEGTAQDADRLEEEEVGFLALECIRAIFQSQNRAQIRDGAVAFMRYVADEAERCSAADAVSGLQLWAATLFQLITSWTPVQQDRFILLFTANETLTRHPLEKLQDFRVASLYAKCILGVLRSDMNLIGLSVIDMLLGLINQTIRLAAAVAPRQVPALHQQPAADLERTNTTTSQTGAASELLPLLKDCIANLARHVYYAGQVTDMISFIMLRVKADPSASDKDTTVATDGGVGDTSSTLTRNKPASIIGGGFSSGSGRHTALEIVKNIIEIAQSTRQYSAGSTTINRHAVPLGVWEGSQWLAKDSSELVRRTYREALLAWAKYEADDGDAALIDFEAADCIERLADSKRPASLHGSTSQSHRSAHPQLLMLPKFGEERRMSSGKNSEGSEEKPRARSNNLRDIIDGKVFVPPREMDGNPIDVRALMATVKVDRSRTGLSMEPPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Z2</accession>
    <name>A0A9Q8P3Z2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00792</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756799.1">
        <property type="nucleotide sequence ID" value="XM_047899940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Z2"/>
    <dbReference type="GeneID" id="71980670"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00792"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF2">
        <property type="entry name" value="ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="25139" checksum="E3DEE4CD1459B0C1" modified="2023-09-13" version="1">MGHPTALPAYRPEDEVSLEGLQHDHDAVLHEKKGSTSIDGADMTRMGKEQELRRNFKFVGIVGFVTILQATWENVLLSNYFGLLNGGTAGVICAEMASMAPTSGGQYHWVSEFAPPSLQKPLSYVVGWCCCLGWIAGVPSCCVQLAGMVTTMVLLVHPNADVNQLWQATLLLFCFIVMAAAFNIFFAQHLPLAEGIILFAHIFGFFVFLLAFWILGEHAPASRVFAEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P643</accession>
    <name>A0A9Q8P643_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758798.1">
        <property type="nucleotide sequence ID" value="XM_047902992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P643"/>
    <dbReference type="GeneID" id="71983722"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03844"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="191" mass="20866" checksum="F4CBCF8AD65C0BE0" modified="2023-09-13" version="1">MHDDQLENYEDSSITTLLRVHSQKYSAQNQPSAGLRSNRNPVSLDTRDVLITAQTLIDDVSNINAGVESLRKHVAAFDGSPLTEAPLLLDFTAIHLANRKGFADANLRQTNFNASESMDITVAKKPEFEKTGQNPTVIGTFELLLDDHDTFSAALVQKISANFLGLRPMFSVARAAKSIMSLPSFMSVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6G0</accession>
    <name>A0A9Q8P6G0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759158.1">
        <property type="nucleotide sequence ID" value="XM_047907708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6G0"/>
    <dbReference type="GeneID" id="71988438"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08560"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="184" mass="20796" checksum="758A0E9CCF0E9D11" modified="2023-09-13" version="1">MRDGRRADGRPKLLDPTSAYLQVAQHEHRLSELREEVRQATAALQSFANDYNSKLAEYLAFNGLDTHQTFAKLWQMNNGESSESEHARLSEDLNKSQRRYEGARRAVREVLKAHNTPSEVSLGPKTSDYITGPSAPEDAVRTALVRTPLTRIREWHANVANEAISAPDYLHVEHSTCSNEQSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M0</accession>
    <name>A0A9Q8P6M0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08153</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759515.1">
        <property type="nucleotide sequence ID" value="XM_047907301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M0"/>
    <dbReference type="GeneID" id="71988031"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08153"/>
    <dbReference type="OrthoDB" id="2104723at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="8">
        <location>
            <begin position="91"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO15149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="342" mass="37468" checksum="4852D8695D54BDEE" modified="2023-09-13" version="1">MATFCMQTLGCEVSAIHTVNYSNHVGYRTFTGRKTTPEEVADLYAGLKTARLDHFDMMLSGYCPTAATVEQVGKIGRDAKFRASTKPGSFFWVLDPVMGDNGRLYVAEETVPAYKGLLQSADLILPNQFEVEVLSGVKITGLGSMEEAVRKLHQEYTLPHVLITSIRLPTTPGSDRDNDKAELSLIGSTATSDNRPRLFRVTVPALPVFFSGTGDMFAALLVARLRQAAAQAGLLEIASWRSPDDVAAQDLPLAKATEMVLASMHAVLKDTAAHYERVKKGLDEETELNEGKGEEGAKEREMERHLRLTRAAEVRVVRNARALREPLDLGDFKAEAVNVSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7I6</accession>
    <name>A0A9Q8P7I6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit tim50</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CLAFUR5_03899</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM50 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760520.1">
        <property type="nucleotide sequence ID" value="XM_047903047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7I6"/>
    <dbReference type="GeneID" id="71983777"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03899"/>
    <dbReference type="OMA" id="NLRQPYT"/>
    <dbReference type="OrthoDB" id="287041at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000019">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="11" id="KW-0811">Translocation</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
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        <location>
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            <end position="461"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="554"/>
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        </location>
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        </location>
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        </location>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="606" mass="66918" checksum="D7DC6EAEC88D7945" modified="2023-09-13" version="1">MLPRAALRISRGPLLLRSYATKPPRPPAPSSSRPGKPPAPRAYPSGPARQTSPGTALPKDQTWKPKDSIPFGGPAAATPSGAGAAKASSGAESPVEGARPTGPETTPRASPLEEPTPPSQEPIAQKLGADAPAPGSPRDAAQEKEAAAEQQRQPPQQEQPPQHTGPLPDLRQGIPSTFDFEFGAAKQKQDAAAERESQDDKLDLTGISPEEGQRQKDREERQRDRSAYETSVDRRRAQMSNYLYASIVLAAVFGGLYLARPFSQSEDIPSGLEPGEADGWAPGKLWARVRARLGDQTGYYTEPVFPKLLPDVPESQRPPYTLVLSLEDLLIHTTWDRQNGYRTAKRPGIDYFIRYLSQYYELVLFTSVPRAIADPVIAKLDPYHFIMWPLGREATKYEGGEYIKDLSYLNRPLEKTLIIDTHAPHVKNQPENAIVIPKWSGDPQDPHVKDLVALIPFLEYVATMGTTDVRTVMKSFQGKSIPEEFARREAEARKRFNEQLADERRRKPRFSLGSIAGSLGVKGGSAMGGGMALADGQSFAEGLAQGKMLSDQIREQGQRQYEHLEKQIRENGEQWLKEEAEEQKRLMEVQMKEMKGSALSWFGGSK</sequence>
</entry>
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        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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                <person name="Samaras A."/>
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    </feature>
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        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="460" mass="49510" checksum="B105DDEE89BFC6B8" modified="2023-09-13" version="1">MLGLRMGAVQWDDPPDFKPGAASKAAREEEVEGVDFGPARGVVQWDEPAGPDDGKPATSSNFYKNIRPANIQTAARLNSPSQEEMARGAGLAQWDDAPDSKPAATQKRQGQPGRTEETGSEGLVASKNSSESEQSWHEVEETDYDAAPKGWSQVDDDGPPLHLMLESGQETSTASAGTAPTAPETPINTVMQYAEEDYDAAPMSWSQVDDDGPPPELVFRSTDASHDLTGSISRVMRFDGHSSTTVQKSTRYDTAPANWSQVDDDGPPPGLVFRSADAVREQTDRTSRVVRSDAHETSTAYDSAPVNWSQVDDNGPPPELLLRVAEQESTQRGSATNSRVYAGEEPLAASNEDTPPTQPIAQSPRATTSPRELPALTEEHERGNVESEPDSGVIPAQEDETSTPSTPSKPTRALRPTSQGDNSSTAKSSAGSPSSSKRPTRSKKEHKEGFFRKLSTRLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P815</accession>
    <name>A0A9Q8P815_PASFU</name>
    <protein>
        <submittedName>
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    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04030</name>
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    <organism evidence="3 4">
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        <lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760969.1">
        <property type="nucleotide sequence ID" value="XM_047903178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P815"/>
    <dbReference type="GeneID" id="71983908"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04030"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="605"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="698" mass="78270" checksum="A34EE2F8A550713A" modified="2023-09-13" version="1">MAEHLYAKLPLERLPVRLQRLLQTPVPRSWILPATLTWLLGLAPLAWFVYKRTSRGVSKKKDATTTDPGLLVKGTRFEQYQTPSGHVYPKIRTFYHEHQKKANLPADLPLLVFMHGLGGSAAQFAPLLTSLVNIAPCLAIDLPGCGRSEFLPKENEAYTTTALAELLFAAIDRFRNKDCNQKVVLVGHSMGCSISALLASNTSPLAHLCSEHVLGMIALCPRSSTITKHELQNIQYLNWIWSPLFDLVRLHDRRGGVDSRSVLRVVGEHADSETKRLQLRFNEQSSSAVFQKVLLGIYLQEKKTAEKGEESLLGKRVWSGMKVPLFLVAAKKDALAPPENVELITDWLTEETKRQDSAGGQQDYADTENEDPMKDAHLPGDKAVEDSADIEEVAPDQLGDLQESQQPKQTSIIPAVAGDVDLAARRLSSNKHEQPYLTTESHTIEEAQTESKHAFALKTTVFPQSSHGLLYASKDVRILASLIEGFLAKYVDERLAPSWQLRHLMSTDKWDVKNLAKWQKVQNCSEPIGGVFRAMKTMREIDEAHNPREFVKKYSYRIRPDGVAMVIDISHDTPVYDKKGLEDNGVEYHKFPTVSKEPPTEDEVEQFVGLVDSLRASPKIAGAGSDTQPTVGVHCHYGFNRTGYFICCYLVERVGWKLEAALKEFAEKRAPGIKHDWFINTLYARYEARIERRGTIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8P2</accession>
    <name>A0A9Q8P8P2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rho1 guanine nucleotide exchange factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_05744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761796.1">
        <property type="nucleotide sequence ID" value="XM_047904892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8P2"/>
    <dbReference type="GeneID" id="71985622"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05744"/>
    <dbReference type="OrthoDB" id="2272012at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="522"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="897"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO17430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1225" mass="138558" checksum="09BDE0E70B2E39B7" modified="2023-09-13" version="1">MAQYHPQQGREYAHGPPNIGPSTDEQRNAAFRNVFGADPRAAGRSQTMTGAPPVMPQNRSNTMSAASGQYMQRAPPMRPGAQPNGYPRPPGSSDGVSNGFPPPVAQYPNGQYSPQRRPQQQPLPQPIHPHRAPYGAPQRLDARQPQPQPGQYQRSFTQRGPPYGPSGPTPALNNDAYRSQSMASIPRPNFQPPASSISPAHAFRQQPYAQSNMTRTTAQGRVVPDRPQDERTMSMSSYSRDADFAQTMSGRVIPNRRRESGDPEGTMTNGHTNGYHDRAATMRHPSSSSHTTQGSRSMSMASTVVSPSDQAHSPRPSVSTAQRSDSQISRAGTMVAQKRPSLVYGALLSNVATAFRERVPLQEKEKDGLVYKNAFSGFDAVELIAYVIRTSDRNLALLLGRSLDAQKFFHEVAYAHRLRDSPSEIYQFKETMGEEVPEVNGVFTLLTECYSPTCNRDNLCYSIACPRRLEQQQRLNMKVTPGLKRETSRSSLHDEAQSDEQKLWINTVSKEVSDSVSDKEKKRQEVISELMYTERDFVKDLEYLRDFWIKPLRMPDVSPIPEHRREKFISTVFSNCQEVHSVNARMAQALTRRQQQNPVVRNVGDIFIEYVPQFHPFIRYGANQLFGKFEFEKEKASNPAFARFTEETERLKESRKLELNGYLTKPTTRLARYPLLLENVLKNTDENNPDMKDLPKAIEQIRGFLSRVNEESGKAENHYNLMTLNTQLKWGTIPHMDLKLTEETRQLIFKSSLKKTVTAEQADVTAYLFDHAVLIVRVKTVNKKEEVRVYRKPIPLELLQIREMDYIMPRVGISKRPSSSIIPGVGRVTAKPPINEQGYPITFKGLGKGGYELTLYCTSQIQREKWMEHIMTQKEKLSERHKIFTMAKLNEGYFNATVRVNCCRPIDGGRKLVIGTDFGVYVCDRKPKDASMKPKRVLDTKLVTQLEVLEQHQILIVLAEKAVYSFPMEALEDEGAGAPSKRGRKICHANYINSGTCNGQTLVCCVKSSTLSSTVKVFEPMESMTKGKKKSGLARMLASGQEVLKPYKEFYIPMESNSIHFLRSKLCVGGAKGFEIVSLETLETQSLLDQADTSLDFVARKENVKPIYIERNTSEFLLCYNDFSFYVNKNGWRARGDWKILWEGSPNAFATWGEKYILAFEPEFIEIRQSDTGGLVCIQTHKNIRFLHQSTREILFAYEDELGDDVIASLDFWGRPQSPQAQIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8U7</accession>
    <name>A0A9Q8P8U7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761945.1">
        <property type="nucleotide sequence ID" value="XM_047905762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8U7"/>
    <dbReference type="GeneID" id="71986492"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06614"/>
    <dbReference type="OMA" id="SWAMRES"/>
    <dbReference type="OrthoDB" id="3649539at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="29753" checksum="E791957708665388" modified="2023-09-13" version="1">MSTTYVELAVLCYEGGADCSTTRIRQSQKPYWPSTATILDRPESWAMRESGTNPLIAQMIFQHFLDAVRPRRTAQYSVFETFFLEPDRPYVDGGTDADTPVGHLGNELISQRFTQLINTFIVATTAPVALTGGFGVSTPFMDYNTSRTDLQIETTSVIIRCHKMWAICLICLSSLLVIAGLLTAFLDLRRKAPGIFDSFVTSIRDSPYARLQHLSSTEDSVDLARRQQNTRVRIGDVKSDDTHGYNAVATLSGSHEVGRLGSRRLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9K3</accession>
    <name>A0A9Q8P9K3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Polyadenylation factor subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762619.1">
        <property type="nucleotide sequence ID" value="XM_047905509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9K3"/>
    <dbReference type="GeneID" id="71986239"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06361"/>
    <dbReference type="OMA" id="YGSSMVQ"/>
    <dbReference type="OrthoDB" id="16717at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="Pfs2-like"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40_rpt"/>
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    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
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        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
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            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
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        <location>
            <begin position="214"/>
            <end position="255"/>
        </location>
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    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
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        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
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        <location>
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            <end position="358"/>
        </location>
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        <location>
            <begin position="419"/>
            <end position="463"/>
        </location>
    </feature>
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        <location>
            <begin position="481"/>
            <end position="594"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
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        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
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        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025498"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00026154"/>
        </source>
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            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369034"/>
        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18253.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="65590" checksum="7E93D18AE3B53083" modified="2023-09-13" version="1">MERDFHGGHGGYERDGNSRPRGRPNRRNATDIGTTYVNFLGNRRAPGRGTRGFEAERPVASYIANMLPPIARKARPADSIPAKHLHTAFNKVRHHVTAVKWTPEGRRLLTGSTSGEFTLWNGTGFNFETIMQAHDNAIQCVEYSHNDEFLISGDVDGIVKYWQTNFNNIQEIHAHQDKIRDMSFAPTDTKFATASDDQTVKIFDFNTGVEQTTLTGHGWDVKSVDWHPTKGLLVSSGKDHQVKLWDPRNGRALTSLMGHKNTVHMVRWEPSNGVLLASCARDSVRVFDIRMMRDVFLLKGHEKDVNSLVWHPFHSSLLTTGGSSGGMHHYLLDEQNNAQHGAPSTLSPYDSKNPTEAPAQSIWPAHVLQAAHDWSIWSMDWHPMGHILASGSNDKATRFWTRPRPGEDSYMKDKYHIGQDEAEKQGTFNKKTACEEEEAEEDDDEDAIDDQTQQSSLPGLISRSKLPGLGAAAVPAFAPPFPGHGPQPVQAPSFMPPAAPSPEELAALYQRFGGQLPPPGQFPPPLASFQPQGMPLGFAPPQGYPPSFGDGLPGMGQPPAPPSRDGGVRKRGPLPDQAEALKQEMRAGRYTKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9U4</accession>
    <name>A0A9Q8P9U4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_06635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047905783.1"/>
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    <dbReference type="GeneID" id="71986513"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06635"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
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        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
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        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
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        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
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    </dbReference>
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        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21081" checksum="32F222FCAEC1D451" modified="2023-09-13" version="1">MSLARPIPLLICSVGNPGTHYANTLHSAGHTVLNKLAAHLEYSQFSKERTYGNGLLSRPPISGGPGDWTLWQSTSYMNDSGKGTRAAFLAWQKTIPSDVQGKLVVVHDELEKPLGAVSVKEQGSPKGHNGLKSIIAHMNNTPFVRIGVGIGRPVSRESDDVARYVLKKMTSEERNVIDGSVEEIVRRLGKIEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA01</accession>
    <name>A0A9Q8PA01_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07251</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762985.1">
        <property type="nucleotide sequence ID" value="XM_047906399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA01"/>
    <dbReference type="GeneID" id="71987129"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07251"/>
    <dbReference type="OrthoDB" id="69641at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23822">
        <property type="entry name" value="RWD_ScYIH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="8">
        <location>
            <begin position="7"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="31703" checksum="09BC887713FC992B" modified="2023-09-13" version="1">MSEDLRDEVTSINSIYGDHTLSLIESDIYALSLPSQPEVSLRLEFPSDYPDTPPSVLGTQHIGDAIAKGEGTAILELVRDVLAEIYAPGTPSIFELIETAGERLQQLGLDRSSKDEEEQNAQTNGQDLHSDFDDLNISDAKQPLDELGYPPPWTTSEPVSEKKSVFIARAAPVLSVDEAKSYLAHLLATDKKVAKATHNITAWRIRGENGVQFQDCDDDGEDAAGGRVLHVLELMGVWDVMVVVSRWYGGVKLGPDRFRLINQCARDAVVKGGFAAVEEEKATGKKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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            <end position="240"/>
        </location>
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        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
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        <location>
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            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="31547" checksum="712286CA486CBEBC" modified="2023-09-13" version="1">MAPRVVEHGTHARQQEEKRKSMSEMLLDYIARTHGLSDNINSQGAPEHLLAPDIDPLEVRSDAKKAEIREEQANIAREMQWSNDEGFELDDHAFREDSLYGRQLLPDDLATSDDNEQKTVPFPTTPYATLHRDSGPWVEPKVAGYYLDQWPGATPPRHKQLDPAAWSRMVGEDAYVPSSASSSPLKRTRKPTAKATASTDQFPKPPPTPLTPRRRQPVAQDVVANPSNPHNTRSATSSPLTARRRQPVAQDVVVNPSNPHNTSPLTKRKRADSGTSCPSTAASTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <location>
            <begin position="205"/>
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        </location>
    </feature>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="26042" checksum="E2767CF11D8FB995" modified="2023-09-13" version="1">MDKIIQFAQSYENAEWVTITLENTDKTYTVQKALLCQTSDHFSKALRRDSSMEASEQTAHVPHCTVETFSAFLYWLCHRQLPDMRSGLEGAHPDIQEGHSIAHQSLLVLLWSFGHDWEIPELQNATMNTLLDLLQCTSVAVEAVQLAFERTGNGSEISEVLASEIYPEIYNKHSSEQKLHELAAIPGFLSASLVAARDYHNLGRDCSSTDDAPSGQRDRSEFMVRERRDGL</sequence>
</entry>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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</entry>
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                <person name="Stergiopoulos I."/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="77" mass="8837" checksum="F1CF4724961EEC78" modified="2023-09-13" version="1">MEFPFIPSIVNEDGFTTDQIMGDRWTASRKVHVDAGEGEEILIKLEDVVLKLWRGKCMAKARIEQTGEILTTNNWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBK1</accession>
    <name>A0A9Q8PBK1_PASFU</name>
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            <fullName evidence="2">GmrSD restriction endonucleases C-terminal domain-containing protein</fullName>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763850.1">
        <property type="nucleotide sequence ID" value="XM_047906468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBK1"/>
    <dbReference type="GeneID" id="71987198"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07320"/>
    <dbReference type="OrthoDB" id="3162605at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="GmrSD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094:SF15">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="GmrSD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040507019" description="GmrSD restriction endonucleases C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="GmrSD restriction endonucleases C-terminal" evidence="2">
        <location>
            <begin position="105"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="23021" checksum="A93DF0DD27D5F675" modified="2023-09-13" version="1">MGLKTLLIAAAAASVAIAASVEEQLAKRGNLPTPVSASTARTYLNSITVQAESNSPAYDRDLFNHWITISGACNTRETVLKRDGSNVQTDSACASTSGSWYSDYDGATWTAASDVDIDHIVPLKEAWVSGARNWDNARRQQFANDLTRPQLLAVTDNVNQAKGDMDPAEWLPSRTAYHCTYIRAWVQVKYYYGLTMDSAEKSACQSILNGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBU3</accession>
    <name>A0A9Q8PBU3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763939.1">
        <property type="nucleotide sequence ID" value="XM_047909258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71989988"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10110"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="319"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="607"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="193"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="543"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1286" mass="144659" checksum="22901C6D50347C29" modified="2023-09-13" version="1">MADTLPQALQKLTLASQSVDDDIDDLLDQVKPRKRLRKSPDDVKKKLGADFLTPSTSFSPEWLDRLQQRWDAPTNYNELFALGPTQTRTIIRFTREGLEGRATGYKEVTVPANSATAKNSTSLRRKPASRAEFVRGAAGFYPFAPGGLDAVEATAAYEDELFQQNEANGVRKSSKLSKVINFAAGGGLLEVPPGFKRGLRVPDKPKQDDESAKEVEEVLDEETDDQHPQSNGVPLPKEDGEADDSEEGEGEEDIDDLLPLEFPALAAHGPLAMARNKHGGREWAHMVDVNRDVTNFRELVPEMARDWPFELDTFQKEAVYHLENGDSVFVAAHTSAGKTVVAEYAIALAAKHMTKAIYTSPIKALSNQKFRDFRTEFDDVGILTGDVQIRPEASCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDSERGVVWEEVIIMLPEHVTLICLSATVPNTYEFASWVGRTKKKDIYVISTPKRPVPLEHYLWADKKMFKIVDASKHFIEKGWKDANDALTGRDKVIEAEKKAKEKEEAAVAAGRGGRGGRGQQNGRGGQQRGGGNQRGGPQQRGRGQPATRGQGNIARTGRGGGRTTAAQDRNIWVHLVQHLRKEDMLPCTIFVFSKKRCEENADALSNLDFNTAAEKSAVHMILEKSLTRLKPDDRTLPQIRRIRELLSRGIAVHHGGLLPIVKECVEILFAKTLVKVLFATETFAMGLNLPTRTVIFSGFRKYDNKQFRDLLPGEYTQMAGRAGRRGLDSVGYVIIVSPGADEAPPAGRLRQMMLGQPTKLRSQFRLTYNMILNLLRVEALKIEEMIKRSFSENATQALLPEHEKQIKVSEADLDKVVRQQCDICDQDIDACHEASVEYQRLTASLHLSMLATPVGRRLIQAKRLVVFRGKNDVRTAGIILRDGVTKGSPPTVQLLEVISRNPRKRQDPDFLPYLPRFRRRFVPLPQTENDMQLRTTTVPLDDVEALTGSHIQMDLAAVLQKDKDALADVKKELLETCSSWTSSSWNELDYYKWLKEMDIRTLLDTRSKAAREAQERACIHCDNFPKHFAMAHDQWVIKDKIDSIRQLMSDQNLQLLPDYQQRISVLKDLGFIDDQSRVELKGKVACEIHSADELVLTELVLENVLADYEPEEIVALLSSFVFQEKTEMTPTMTTALEKGQETIVKIAEKVNHYQILHQVILSSDDSNDFVSRPRFGLVEVVYEWARGMPFSRITDLTDVLEGTIVRVITRLDETCREVKNAARIIGDPTLFTKMQTCQELIKRDICATASLYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCB7</accession>
    <name>A0A9Q8PCB7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-iminobutanoate/2-iminopropanoate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764201.1">
        <property type="nucleotide sequence ID" value="XM_047909283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCB7"/>
    <dbReference type="GeneID" id="71990013"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10135"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="31234" checksum="A6B2EF9FAAD0DAC1" modified="2023-09-13" version="1">MICRLGRAKVDFEHIETPQHTSTGHATIVGVAAPWVKSVTLLVRDCRCEQSPTKRRSLHAGCVERGMLAPHPHASCGGVKPLAYGILKISFLPFYVRKRQNNYPLLPTGQQHLHHDSNTMRFEVIALMAFAALASATLAPNYTSKAGVEIYNPSSFFNTTGPWSLMSRAGDYLYISGMRGIHQENSTLTPTGLPRVRKAYENMRDLVELAGIELTDCARLVVYVTDMYRYRPMCNEVQIELWGEDASRYPPRTILEVDRLNDDDTVEVEGTFYWPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCD3</accession>
    <name>A0A9Q8PCD3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764197.1">
        <property type="nucleotide sequence ID" value="XM_047909153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCD3"/>
    <dbReference type="GeneID" id="71989883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10005"/>
    <dbReference type="OrthoDB" id="10580543at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30654" checksum="CAEC10DC8E56F6F2" modified="2023-09-13" version="1">MQSSPPPADNSIAKLSASLQLLSAKSEAAAKALGTFELVEMIVTYLPPKGVVAVQRVGHIWNNVSKDIIKRSPYLTETLSTIPVSSVSRLEKSKSRPDTQFDSLSAKSQDPNVVDSMIICKIHPAFTIRNTGDKLHQSLQLSIGSKELLSWRPGPWRAMFVTQPPITFDLLYAVNGPADSIRTQKDAARFGETAVTLGGEGAVTLGAVQDVVRKSLGGRALPDTKYVFPTRIVFDKESRDRFFIHEESGWVKFAREHPERRLSEYFFGLRVNWQAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCW9</accession>
    <name>A0A9Q8PCW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764592.1">
        <property type="nucleotide sequence ID" value="XM_047909856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCW9"/>
    <dbReference type="GeneID" id="71990586"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10708"/>
    <dbReference type="OMA" id="MWLTDAQ"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000137">
        <property type="term" value="C:Golgi cis cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="15832" checksum="BB56CB3036349927" modified="2023-09-13" version="1">MPTLWLSDSQKIGVAFCTGGGFFLLFGLILLFDRALLAMGDILFLIGITLLLGPSRTFLFFARKQKWRGTAAFWAGIGLILVRWPFVGFVVQCYGMFILFGEFFKTIAGFAYNVPVVGPYLARALSVAGDKAGAEERAHKDLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDC6</accession>
    <name>A0A9Q8PDC6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764726.1">
        <property type="nucleotide sequence ID" value="XM_047909082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDC6"/>
    <dbReference type="GeneID" id="71989812"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09934"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="151" mass="16480" checksum="FD034AE979F59453" modified="2023-09-13" version="1">MFDALREPESRTMVPLVTLVAIESVRTAARNELVEELTRAATCTRYYSHDTDYAGFLTSIAKTMGDTTWPPKFSAAGVDTLGAALSKIENLPDYDLTCCVETVSAGRSKSSVAKYTCASIVQKVALKCEGLCLQCIVEDESDLTKRCTKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDP0</accession>
    <name>A0A9Q8PDP0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ASTRA-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ASTRA chromatin remodeling machinery complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ASA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764873.1">
        <property type="nucleotide sequence ID" value="XM_047910723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDP0"/>
    <dbReference type="GeneID" id="71991453"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11575"/>
    <dbReference type="OMA" id="YQRQSMQ"/>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="393" mass="43129" checksum="03E14127ACB996DB" modified="2023-09-13" version="1">MAQDNTIQSSEQPPAQPSYVLRGHSAQIHAVHFFRDNTRLVTGDADGFVVIWSTASKRAVAVWKPHSTTIVGLASWNDDKIISHGRDNKLLVWQLPGNAESDCSTILPIDDAEIERKQPWLLHSLRVNAWNFCSFTSIVLKPDGHNDLPAEGILVATPGVQDGHVNVTCLPDEQRIATIPAPQDVKTGMVMAIGLQFQPNGRSMPINELLVIAGYESGLACIWQQEGATRKWNLVYTQKHHSQPILSLNISPSQSCFFTSSADAVVARHTFGNSPTPAKIVQTKHAGQQGLVVRNDEKILATAGWDARVRVYSVKTMKELAVLKWHKEGCYALAFAKVGTGVESSRGEDGKGKSSEVEEGERTVSERRALAARTTHWLAVGSKDGKVSLWEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDQ6</accession>
    <name>A0A9Q8PDQ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764893.1">
        <property type="nucleotide sequence ID" value="XM_047910607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDQ6"/>
    <dbReference type="GeneID" id="71991337"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11459"/>
    <dbReference type="OMA" id="HHVSKAH"/>
    <dbReference type="OrthoDB" id="5078320at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="3"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="492" mass="54339" checksum="176B021056E684AC" modified="2023-09-13" version="1">MAKKTIYTKITPLPRNVPRQLAIEMLHSHKEVIELNPLVTGVKQIDAPRDAPNDEYFSQWYEISEIITWGFGLRKKIAFKGVFHDQPYGLQSHVYAPMGVDLRNKYRIGGNQPGEPRETRELGVDTPLDGLYLREDVEIVCNIALASFVKKETKEATGKMIERLARKAELLDEGKLHAMFEDGMLKTAKPSAFSDDGSQPSGSMAGTPPGSPSPSMAGFGSPRLDKKGYGNYHDISRTSSQHRTSQYLPAYQQQGYNGPDHARLGAQQTMPMINELPGSYEQPPQNLFPDPLKPHGAVFRSELPGDSSFNSTTAPSQSFGSTATPSPQPSPRAPSQSSLDLKPPVQYQAYAPPSQQHPTDRNTTLTPSHNSYNEHQQQQPQPQSPNYSRPNVAQWQQSVSNTSQHSISRNSSTGDGTSYQQHQQQSRPSSSIVPDHQRFSNLSVQDRPPQQAPRPVSNSGYQHATHAKCPVCGLFEGDEAAVSHHVSKAHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEL9</accession>
    <name>A0A9Q8PEL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_11525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765386.1">
        <property type="nucleotide sequence ID" value="XM_047910673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEL9"/>
    <dbReference type="GeneID" id="71991403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11525"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="109" mass="12321" checksum="6BE321FE63733EE3" modified="2023-09-13" version="1">MIFFCYELDYDGPSDDSGISPVLYHVRMFALAEKYKAYGLGLLAVDKFRKAASMESTVEKDLVGAIREAYETRDEEGLLGRVILDLVGQQWVDERVFGEAIEVEEVEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEW9</accession>
    <name>A0A9Q8PEW9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765695.1">
        <property type="nucleotide sequence ID" value="XM_047910421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEW9"/>
    <dbReference type="GeneID" id="71991151"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11273"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="275" mass="30990" checksum="3ABEB2172FC8252C" modified="2023-09-13" version="1">MSTNLVDIMAERAEEKVMRSIKVIAAAPCPVHREAFACSCAVAMATMTDWDHVWCKRIWCNMTFETELLSKDHAWTYTGSRESHDIFTTAEGMTPEQFVRKQVQEGIMKHFLAPSGKLNDTTQAMLELWIARNQQWREMYGTRDVATEKWIEEAYRDAPMQNVPKEATPADAKVGDVVNITEMVPSQIVSMETADRQHGFAATFTELQPADTKGWTPYGGCVEEVKLCHPGCKVGKAMFEAKLKDASKIALDLLEPRQGEVRFKLVVYGPERPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFI0</accession>
    <name>A0A9Q8PFI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">M-phase inducer phosphatase</fullName>
            <ecNumber evidence="2 10">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09112</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the MPI phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2 10"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766010.1">
        <property type="nucleotide sequence ID" value="XM_047908260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFI0"/>
    <dbReference type="GeneID" id="71988990"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09112"/>
    <dbReference type="OrthoDB" id="26523at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110032">
        <property type="term" value="P:positive regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01530">
        <property type="entry name" value="Cdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000021">
        <property type="entry name" value="M-phase inducer phosphatase cdc-25.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="12">
        <location>
            <begin position="370"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="242"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="558" mass="62230" checksum="8E97DDACA8FD0A57" modified="2023-09-13" version="1">MEYSSPLAAIRPQPHPGFGGNRKDIPDFRSINHGCNTIGPFDFKAMSMHTQKPRRPDYFSLRPVRGSSPTASLTADLDANFHIDKSPAAPTPRRSLFTTDLFRPRENVATPPIEIEPATTPPIVSSSPYCDAMDISPLPHKLPLTFQVTLPSPTPELTPEDVHEISPDLLQPDGLSEPPPSFLALPEPVTRPALSRTKGYSASCIPQRPSSAETQLPPFRFGNVATSGLACSSTPCLLDSFTDSPVDELRPSSAAGSMPPPPRRTSLSQRNNGSPSAGHVRKPSAGRPNFVRPQRKMMRRSLSMFQHPDDVMKEEQDTFESQPSLLSSVMDVEQEHSPKLPHFVPDEPDSLPRISQETMIDVLDSKYTDQYDRIVVVDCRFEYEYEGGHIDSAVNFNDKQQLATELFCENVPANTLLIFHCEYSVHRAPLTAKFIRSHDRTVNAANYPNLTYPEMYILDGGYSKFFSEHPSKCFPQNYVEMNDQRHEQACERGMAKVKNQRQKLFRNQTFAFGQNDDMEDSPTALGRTLGPRSQSTFAVGADIAEGIGQSFQRRMASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG09</accession>
    <name>A0A9Q8PG09_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clock-controlled protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766182.1">
        <property type="nucleotide sequence ID" value="XM_047908177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG09"/>
    <dbReference type="GeneID" id="71988907"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09029"/>
    <dbReference type="OMA" id="MITHGAS"/>
    <dbReference type="OrthoDB" id="4094614at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040238073" evidence="2">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="22267" checksum="BDE8FCC125166568" modified="2023-09-13" version="1">MQFIAVVLAGAAVATASYAPPPKDSYEAPKYEAPAPPAYAPPAYTTPEAPVYSAPAYTPAPNATASYQKPSYVTEVVSSYETYCPGPTMITHGASTYTVTEATTLTITNCPCTVTKPAYTSVVTACSTCAPVYKPTTPVMAPSMPASYPAPAPSMPPYQPPAGPVPPPYHGNNTTPYSPTKPTGTGSYTTAPPSYTGAANKASFGVAGLLAAAGLVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGZ2</accession>
    <name>A0A9Q8PGZ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766597.1">
        <property type="nucleotide sequence ID" value="XM_047908800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGZ2"/>
    <dbReference type="GeneID" id="71989530"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09652"/>
    <dbReference type="OMA" id="NICFASR"/>
    <dbReference type="OrthoDB" id="3630829at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad60/SUMO-like" evidence="1">
        <location>
            <begin position="147"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="25353" checksum="5103A668E36B9ECC" modified="2023-09-13" version="1">MDSLPAHNPMKVLDRDPIVKADPGYVNICFASRSSSFALTFKVRKSHMFKDVKAAFGACTDQQPGGLVYTFKGQVVEDANTSEQLRLKNGDMVEVAAVGDADFTGACSEHRRVTELDRQGFQCISVMNAGESLVVKVRLLSGYTQPYCIKPNTQMSKLVADFEQQVGEQDLRFITFDGDHLHGRRNCTAENAEIEDGDTIDVFREQIGGGGTLIQKFEAFLRVPQRHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH70</accession>
    <name>A0A9Q8PH70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Alpha-L-rhamnosidase rgxB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_09175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766723.1">
        <property type="nucleotide sequence ID" value="XM_047908323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH70"/>
    <dbReference type="GeneID" id="71989053"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09175"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040494966" evidence="10">
        <location>
            <begin position="23"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="431" mass="46242" checksum="80512A594E2ABDE5" modified="2023-09-13" version="1">MMAKLTFALSTILCWFLSLTVATPTLTRRTTCTIPAHGNGTDDTPAILTASKECGDGGHIIFTPNTTYHIATVMNTTALSDVTIDIHGTLLWSTDLDYWLSNSLSVGYQNQSSAWFLGGSNIHVNGHGIGTLDGNGQAWYDFVQGESNYPNRPMGLTIWGANDSTFEGLNFRQSQMWTMAIIHSNNLLMQDISVNSTSENNSPARNTDGADTLYSNNITMRRWSVDNGDDAIALKGNSTNVLIEDCVFRTGQGFALGSIGQYEDRVEVIENVVVRNVTNIETKYAAYVKTWTGERSGYPPNGGGGGNGRIRNITITDITLDRGRASPFTITQCTAFGGVTPGDCDTSTFKISDISLTNIKGSVNANTVAIMQCSEAAGGCDDIQIEDVVVQNIGSSANATFPNAYRYLCSNVDEPIGFQCTGNGTTNPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIX1</accession>
    <name>A0A9Q8PIX1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767649.1">
        <property type="nucleotide sequence ID" value="XM_047911111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIX1"/>
    <dbReference type="GeneID" id="71991841"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11963"/>
    <dbReference type="OrthoDB" id="3945550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="603" mass="67859" checksum="30E49951B6DA658C" modified="2023-09-13" version="1">MSSIFDIFNQSRQPDLPLKHNTERIEIPTRRLVAQDAANPSIVSLGHDLIVMILQVLQDAHPPSMRSVKQVSSNFHHLAAYIACNTLKLDLSLKASVATSDRLLRLEQRGLLAAIHRIEVTATDDELAQPMPPSNGNHFAKQDDCKVMYLMRRLLLLMTGLTDLHWPNESISPATLAILKGRAVRLHVKADSYATNNLDRLIDCSNLHSLSVHQNYASARDCLKITGPLKAVLLSCKNLRHLSFDISQPSSGCVVYSVPTEYCGMGFVDGEKPPALESLNVYSYPFRRQQEDGDDDDDDYQFSVGYPGRGTEQEYWIENFDWSRLRVLEVNDASLALGLMSKLPMLEEVSLKHVYPPAAIKEFYSGVPTSLKSIEAQKLSSVGLAGIVRHGSALRKLQLHQHEGWNRDWKEEAIDNSSLMKVRDECPFIEELHLDIGRSGEWPFDILDTIATFPALRSLTIWLELGMGKDEELATPKVTFSSVEDIFKYLRQRSPTQPSKLRELQVYSGSPPGLGHGYPSAMAFWPQYNSMHFRCSLSERDDEAALGIYTTECPELGAQANEYLRGERETFTPSGEYGFMDDTEQVEVAKDGPKSRDEWKAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJH6</accession>
    <name>A0A9Q8PJH6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767932.1">
        <property type="nucleotide sequence ID" value="XM_047912165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJH6"/>
    <dbReference type="GeneID" id="71992895"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13017"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057230">
        <property type="entry name" value="DUF7908"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25485">
        <property type="entry name" value="DUF7908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040509414" description="Chitin-binding type-1 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="358"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="609"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="72"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="937" mass="95393" checksum="FC9C964A1539AD76" modified="2023-09-13" version="1">MFGNGIALGIAILSLPTAVPSELVTITAYPTTCGAIYTTVTSSSVLSNSSAAISTATESILSIEFSSTASSSAQSSSTQSSSTASSSTQSSSVSVPTTQSSLTESSSAEFSSSQSGLPQYPLDPYTTTSSTTEQFSTTQTPATYSPTPVSDVALNEGSIPFVLQINPGVPGRKRQAGQATYIDADGYVTANASQAVQYVIGNGTLTSTAGGWVSTYEGVNIMPFAMSSIRATIDTVFAFEDLKLHWNNTAFDGGAAQFYTVPASTSGAPAQVVLRLAGPIQSNFKSVTFAVQPAAELFVESSSAIDIATTPIIVPVESVTAPSSAIASVTSSVAIEDGQEVTTAIIIPSSTTANVAPSGTCGPEVGTNCYGAFSGNCCSTFGFCGSGPEYCGSGCQPGFGICDTLLASSSASEASSAVSSSSTLYYATESSVAPISSSEIYIPTNFFSTFGTVSSSGPTPLVSSASFSTAIGSQYVGVSTSSFASSAVTLSSELPSSTLPIYFSTASPVVPNNPSPSSEAEQSSTSSTSSSVTDTTSVSSLSTTSTFMSSITNLEVFPSIVPDSTTSASSVTDLEVFPSIVPDPTSTASSLTDLEVFPSIVPDITTTSTFSPSSASVSADSSDSSMVSSSSASSSSSSSSTSTMFSSSSSSSATISSTVPLTTLSSSSSSSSSSLSLASLENSAPMPILPSSDISILPYSTTTTSSASATSNSVLSSSTPVIVSSYILSASSASSSLSSASSSYLVLTSPTACNFGDPPTFDEDDSYERIDLPQPMYIGTSSSTASFAAVNGLLSITLGTAEYQYNELPSTELPAGTVAPYWADLAVYRINATGPAQGLFYQLDASGVTYEWYLNRAGNRNITFHFTVQYRYANPGIFTYTYYDVGDGENGALATVGLQTSTTSGYTMSYNSTGNITPGLVVTCDTNTNTCTRPAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJN3</accession>
    <name>A0A9Q8PJN3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768011.1">
        <property type="nucleotide sequence ID" value="XM_047912016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJN3"/>
    <dbReference type="GeneID" id="71992746"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12868"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="356"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="49728" checksum="287D4DF02641C782" modified="2023-09-13" version="1">MTRKMEPRREGSAMSAAGLDVNDLRSIMKLDIAASNELQSRIEQLRQELRSGRRPPEEKIELCDMANKDMTRDLIRRIEQIERQGRLTTGDREMLQAFSSRLAVCDKQGMDITELRDWKRDVQKREALPLGGKPRTPETSPCPPVRVTEHLRRAPDMGVRSTSPGPILERVDSRDRRPAAPPRVGSDRTFGMPPSPRRSGQPYFPPPPSSPHRPSAIFGASSSPWQSSERVPQVVPPPPPPPTPYVSSNTRTPSPRFSSQVPYGTPPSSRGSEKTAPTPPASRPRSQYDDARSSSDSLPPRRSMDGRYSADPPSSASSFRRPVYQPPTVAEPRFEAYYDANFVDGDLVLEKSTWPLLYRILDVDPSTPPRIFEHTMKRSLADLSLKHNPVQRPNDPEAPVRWAAICKAYDTLIDPERRRDYDGHSAEPGINDDFAQLSMGGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK27</accession>
    <name>A0A9Q8PK27_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768190.1">
        <property type="nucleotide sequence ID" value="XM_047912081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK27"/>
    <dbReference type="GeneID" id="71992811"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12933"/>
    <dbReference type="OMA" id="TEKEWRY"/>
    <dbReference type="OrthoDB" id="3649537at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="375" mass="41898" checksum="9543F94C4E114047" modified="2023-09-13" version="1">MTSRQVALNFEAYLRRHGRLTHDEELDLMQQGIPLHEHYGLQPEQYLLPPQHFMPCRFIENYDLTVQYGAHSLSSAQHALLTQRAVTGMLPPNAVPTGGYRELQTRPRADSAVASVSRDSKPRVEERSEPASESITRSIELDEAIKNDVPLKRRRKSVELDEDFEDEIPLKRRRKDPAQSTTPKLKVKFKAPPPPPRAQATPAQLITSTPRKRTSTRPKNGDDSDEDYQPPTRSTATTPLPNIYTNASLPYTTSTAPTTAATPTRTPSITSSGRSISPATPRNAPVGTVFKNGTRPIPAEIQNIMAAVREIKIGKDGLPQRTGLRNTLGFTGRDGVLKATSVLWPWYGDTRVFSEQEWKFFASNEEGRRKRNGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK71</accession>
    <name>A0A9Q8PK71_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="5">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_13281</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="5"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768293.1">
        <property type="nucleotide sequence ID" value="XM_047912429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK71"/>
    <dbReference type="GeneID" id="71993159"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13281"/>
    <dbReference type="OMA" id="DGWVNIH"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06448">
        <property type="entry name" value="L-Ser-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000040">
        <property type="entry name" value="L-serine dehydratase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="11">
        <location>
            <begin position="9"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="353" mass="37684" checksum="F4FB215CA48BD57C" modified="2023-09-13" version="1">MAENKLPWIETPLVWSRSISKAAGCNVYLKLENTQPSGSFKSRGIGNFLKARLAESAAQGHGKPTHFFCSSGGNAGLACVHAAVTLSCPATIVVPLSTSDYMIQKLRDAGAKDVIQIGKSWFEADQYLKETLLPKASESGENAVYTPPFDHPDIWAGNATVIDEIAKQLPEVDRHYPVVAKEPNSISSAAPDAIVCSVGGGGLFNGIMQGVAKNFSSSPPHIIATETFGADSLAQSFQAGELITLPAITSIATTLGARTVSRQAFEYAMDKKAVTCAVFEDKDAVDACRRFADDERILVEPSCGVALAVCYMGRLKQLMPRLTEDSKVVVVVCGGSGMSTEILRGYVEKFFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKC3</accession>
    <name>A0A9Q8PKC3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methionine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_13665</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="3"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768605.1">
        <property type="nucleotide sequence ID" value="XM_047912813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKC3"/>
    <dbReference type="GeneID" id="71993543"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13665"/>
    <dbReference type="OrthoDB" id="5844513at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.20:FF:000001">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="entry name" value="Methionyl-tRNA synthetase, Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
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        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
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        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
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        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
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        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="Methionyl-tRNA synthetase (MetRS), Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="15">
        <location>
            <begin position="15"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="16">
        <location>
            <begin position="435"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="575"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="575"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO24239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="641" mass="72187" checksum="726A44DEDB03C619" modified="2023-09-13" version="1">MVAHPILPEEGKKNVLITSALPYVNNVPHLGNIIGSVLSADVFSRYCKARGHPTLYICGTDEYGTATETKAIEERVTPQQLCDKYNKLHREVYDWFEIDFDHFGRTPTQQQTDIAQDIFTKLHKNKFLEERTTVQPYCTKHNGFLADRFVEGTCPLCNYEDARGDQCDKCGHLLDPLDLKNPRCKLDGETPEARETKHVFLLLDTLQEQVAAWSKKSNEKGVWSDNGINITNAWIKEGLKPRGITRDLKWGTAVPLQGYDDKVLYVWFDACIGYVSITANYTDQWEKWWRNPDNVELYQFMGKDNVPFHTVVFPCSQLGTGDKWTMLNTLSTTEYLNYERGKFSKSRGVGVFGTSAKETGIAADVWRYFLLLRRPETSDTEFEWGGFIAANNNELVANFGNFVNRVLKFVNSANYDSVVPAWSQSGLDAEVEKALNQHIKDTNEKLAEYRKEFDAVHLKAALACAREISSLGNLLLQSNKIDNNLFNNERARCDAVVNLAVNHVHLLASVIAPYLPATSRAILEQLQAELLIIPDEWQAQSIPASHKIGKAQHLFKNIKPEKEAEWKEMFGGSELKKAKEEEAKKKAARKAEKDKKKAKKAAERAGQAVESSEKDGAEKPSAGDAVEEVTEGVKQAALQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKR8</accession>
    <name>A0A9Q8PKR8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_13579"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470:SF1">
        <property type="entry name" value="CHORISMATE SYNTHASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="360" mass="39603" checksum="61109AE087C55303" modified="2023-09-13" version="1">MATITWGTIQSLLLFFGPWLLPRILAFYRSLKNRPASQIRPLPTKTSYALAILFISGTLAFLSTLPAFAPENIFRLTQSRLHTNGGVLLTRLATVRSVTAPDEKLRAIFDAGGLEARLLYARYGPQVLLDCTLAKAGDIGAERAFLIYALPSLLTPHLLHLFALGIATSGLLSGKEGARWRTMAIITGLILAVVEIYIISNYNDRANARSVRVNDIDFLHWKMAVYRGLAIAGSDGVLGWVIWLQATGRAFITPPTPGEKILETGAALEKVFAKTRGIGVVRNAALRDGGMRKRVDEYWFKESEVMKDVLEDAEVLEAQRNALRMLDTVRAGRDAEAFIDAVLGPEMNSAAQAHQRVMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM30</accession>
    <name>A0A9Q8PM30_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769240.1">
        <property type="nucleotide sequence ID" value="XM_047913283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM30"/>
    <dbReference type="GeneID" id="71994013"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14135"/>
    <dbReference type="OMA" id="PECDPRC"/>
    <dbReference type="OrthoDB" id="94998at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35606">
        <property type="entry name" value="CELLULOSE-BINDING FAMILY II PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35606:SF4">
        <property type="entry name" value="CELLULOSE-BINDING FAMILY II PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040411614" evidence="2">
        <location>
            <begin position="20"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="274" mass="30074" checksum="042FBEF235CE7250" modified="2023-09-13" version="1">MVALDRFLAISALSLGALACPLGPKTISRRADTNTSSSSTPAASSWSPPSSMTTALDQVWKQTLKEKANWFDDKNWNLDQLMANNGSINYCVRWNTAQASTAENRALTASALQRSLGKWADTLIGFAGFPLTSVDVNVVGYAVKDKSLMQGDVSDIDVYTTADADGVPECDPRCYRGAHLDGDISTCPGGEASRYDISLWLDDSLAGEIAVEDENVHILLHEMGHGFGLLDFYDWVPEGQESFVMMAGSAMEVTEFDAWMLRDWWRKLKAVRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM50</accession>
    <name>A0A9Q8PM50_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S41 family protein ustP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769324.1">
        <property type="nucleotide sequence ID" value="XM_047913695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM50"/>
    <dbReference type="GeneID" id="71994425"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14547"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040256825" evidence="1">
        <location>
            <begin position="39"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="3">
        <location>
            <begin position="173"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="2">
        <location>
            <begin position="364"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="538" mass="59551" checksum="212AFBEA1B4CBC86" modified="2023-09-13" version="1">MSPHHFHCSRTKSSTMPSSLLWTLGAAAAICCPSYCRAHRDRACAEIAGQYRAWHHLQDGSLERQMRWRIPGQLAFDCLRAMPFNATLATAFINAYRPYLLFHSTLDVLPQAPPEYLSPSVDLLAGLAKIRSRAARGDYESHFDFDSDLNRLLSLAHDGHLQIELCSQHLFLFTRDLPLVSISDDGLKLPSIYTFDDAQRRGAHHLDHVSPVVEINGMDAAYYLESHVAMWLNSHDPDARYNHLFPSAAAHLSGAYAGGAWTRYKGKWPGTASSRLKFANGSYTTVDTHASWPAENGPMLYENGPDLFTAACLPTSVPPTDLKRIPTGTGYDTASPPHLYPEPDVEHSDTPVKVYYLASARLSDVAVLQVPSFKARHGGSNYTTATEHILQHAVTEGKTKLIIDLSDNGGGDVELGLNLFRLLFPGRDVYSATRFRAHDLVDVMGQIFSKHYSAPGQAPVDLTILPHDAVNPAQEHVFHSWATLYGPDEYRGTNMSRLYALFHSSATSTCQTPASREDCSIAKSHPPFRPQDIIMVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMM1</accession>
    <name>A0A9Q8PMM1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769701.1">
        <property type="nucleotide sequence ID" value="XM_047913469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMM1"/>
    <dbReference type="GeneID" id="71994199"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14321"/>
    <dbReference type="OrthoDB" id="3335528at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.20">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="334" mass="36671" checksum="5932418E7B5C9D43" modified="2023-09-13" version="1">MPKYSFHVNRKQYHLNWDNRQPPQLTVNSGDVVTFDCIDGSNYQINLNSTAKDVANLDTSIADPVFGPVYINRAEPGNALEIEVLELEHADWGWTAIVPGFGLLGDEFPEAHLKIWNLPTSTPLTNGESKLNGHSHQRLAPFNDKIHIPIHPFMGTMGVAPSQPGAFSTIPPLDTGGNIDCRHITRGTKLILPVRTPGALFSCGDGHAAQGDGEVCGSAIETPMRVTVRFKVVKSQPHVQSPHFWSPPRRLEDEVLPDKGSYSTMGIDEDILEATRKAVRAMIEWLGVTKGLERVEAYMLCSVAVDLKMSEIVDMPNFAIVATVPLNIFVDGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMV2</accession>
    <name>A0A9Q8PMV2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769678.1">
        <property type="nucleotide sequence ID" value="XM_047913368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMV2"/>
    <dbReference type="GeneID" id="71994098"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14220"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="118" mass="13445" checksum="F2BF0F9890CA6815" modified="2023-09-13" version="1">MISHPRSAFTEQSLHQKIHADRTLSIPDLREITREQLQRTVNVREEFIDAAGMHVARLQDEVQIQDVRAKIDDAEGQVLDAKAQGLDVGSLGEKEVKERLCTLVEQQWNFLEKGKALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMV7</accession>
    <name>A0A9Q8PMV7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769736.1">
        <property type="nucleotide sequence ID" value="XM_047913656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMV7"/>
    <dbReference type="GeneID" id="71994386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14508"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046670">
        <property type="entry name" value="DUF6540"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20174">
        <property type="entry name" value="DUF6540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="77" mass="8498" checksum="040EAAB9F7AAF8CE" modified="2023-09-13" version="1">MVHVTGFTGMFEFEAREAPNPTASTSFAKLVVVGALARPATPTQIRQALRNVPIDNRDRGFNCQTWIESALKALKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQG0</accession>
    <name>A0A9Q8UQG0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763051.1">
        <property type="nucleotide sequence ID" value="XM_047906679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQG0"/>
    <dbReference type="GeneID" id="71987409"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07531"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="21344" checksum="D347297DA28D6E7F" modified="2023-09-13" version="1">MKSLEKHIEDYFRALRLCQARQWDAAITTAKRSLTDPSLPRQWQVEDCVIVCSATDDWEEAERFREAAEAVYNTSRIQATPSQKAEATLRDMRSILDQIKAGQDAEPPEETKVDVENDSHDAEETDEDDDELDDSEDDELNDSEDEAVNREPDPLKVIRGTLVMHMPARSLESSSDSEPDSNPDVCVCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR03</accession>
    <name>A0A9Q8UR03_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">C6 finger domain transcription factor iacK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906578.1"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_07430"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
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    </dbReference>
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        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="19"/>
            <end position="49"/>
        </location>
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        <location>
            <begin position="51"/>
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        </location>
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            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        </source>
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            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19238.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="574" mass="63010" checksum="E2D6B44B8A0C1324" modified="2023-09-13" version="1">MTSPGTDSAKAAARPSPLACTECRKKHLKCDAAVPICSRCTYKGLACSYTPSRRGCGARSRRLQSPRPTLPPTPGSEPTDYLPHGGQHRPPPMPYSGTAPTSDASSLSQRPQEASTPGSSSTTSSLRSEDEHLTNLYYSNFHPGHPILLPRSRCSDKTYPPYLRATVKLIGSYYAPGIASDPLQTILTETLRASDARSPEMVQTLLLYVLLLHSRYEPMEATACMSRAVEMAISLGMHTAEFAANQAQGDALYEESLRRTWWELYITDGYLAALHRNTSFRSNTVASTTLLPCEESAYAEGRITITPSTLEMFEDRLFSDEEWRFSSYCYRIDAVRILARVIAVSTNNAAKADTIQAIDNAIASWQLHLPNEKARLVSHGGEMDHLMFQAFTFIRCASIFLHFPRSELPITMPPAADVACAQQHMEQVSPTSTQHAVKALSASKELANLATLPAHDQSPLFICGLVFACIVQLSACCAYSHSDTQQNRDRVALIIGALKSLSRQWPIAQHVTQQLKRAANEIFKPRAVASIPTSSPGPSASDFATFPADLSWLDIFYSEGMQNQLLPEGEMTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URN3</accession>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71990081"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="665"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="665" mass="76996" checksum="E3F8A31702EBA780" modified="2023-09-13" version="1">MRQSISSRLQGKSRSQDEEKATKGIEDAKDGYTPPENVYEAILELQDHQRKDWARWRDKEYAIIPHTDAGGDAYFIGDFYEGIKCANEWEMEEPGPYLQYVKDLSETMPHLAYLGHWMEVTCAPPKWRYMKFFDENRRERRSKAHVCVIDYTDGGGPETETYNNTEELLPALTKAPQTAESRQTRLLIVEDLSRDLVEGLGAFYDIDPLFFLSYIGDYLFHNTRDPWVELPNLDVDLRKQNHFIIQYLRARYFPTEKQYQAAEMETGNWNILRRLDSDRSRKRLQNGLLDKKDASVVLTRAKTSLWIKPRQAGDPVTAILLLDPTVSTGQPLWGGYRPFEGTPSMAALRSNREKAVQAPKRQSLFDDMKYWSLRLSSDDLNRIRSDERCIALPMYRLVIADWLTTLKYMTTQLGKIEWEFEKPHWGENASDISDVLQKLSPWRRNVGYYQTMISEASARLFPPEVHAPYHGLQSSTPALSQDSTSREILASGTDKVGIIALLVDFKNVKRQMDEIQVRIKSIENMATNNINIEESRRAVKQNKNLARLTFLAALFIPLQFTSSFLSISPDFTQAKQSIWLFFVIGIPLTLIVLLAIELTHPEQNSWTWSRCKAIKRQWRAYYGTGKKPETPMPTPPPQQHNRRKSVVRKETTVPWITSRNDTKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URQ8</accession>
    <name>A0A9Q8URQ8_PASFU</name>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URQ8"/>
    <dbReference type="GeneID" id="71990427"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="205" mass="23350" checksum="34814A894EA148B2" modified="2023-09-13" version="1">MDFNYYSLRVLKHMFPNLDKLRGEQPFADDKSRDLAIALSLEVCRAVIGGGVEETVTFDRAVQNIVNTAFTIDQGKISSDDNHSHHTAMNHPEHIGQWRNAEVLTKQLDMMKAFHKRTGEPIGESFMEKQIQTAAERRRARDSSTVQLEEPDDITQISHEEIKLATAELRSNPDQGQANVASHEKNIDRSRKQNFMPRATLQHIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI8</accession>
    <name>A0A9Q8USI8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
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        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11022</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765209.1">
        <property type="nucleotide sequence ID" value="XM_047910170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USI8"/>
    <dbReference type="GeneID" id="71990900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11022"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
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        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="38220" checksum="9638933BF4A7F4C8" modified="2023-09-13" version="1">MLSRFQTTLRATTHYLSHSTNTPVSRATPRWPQPYRYFPHHTRPFTSTTTTMSTDPTASITARLADRSLSTIESAKRKAAYRAVAEHFSPTMRFVGIGSGSTIIYGVEAIKDALAANPPPPGHMNWFVPTGWNSRKVIEAAGLTPIAFDSLPADTLLEVAFDGADEVDEELNCIKGGGACLFQEKLVACRAKKFVCIADYRKDQSRLLTQWPTIPIEIAPIAYASVLRELRALGSPAPVLREHTLSKTGPVQTDQSFYIVDAPFKQLLTSKDLAAGKDGSGKDGVWDVDTLARTIKGIAGVLEVGLFHGINGIQAQALGLQGGQKPVAVYFGLEDGEVEVKRYSELEQTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU88</accession>
    <name>A0A9Q8UU88_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU88"/>
    <dbReference type="GeneID" id="71991917"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12039"/>
    <dbReference type="OMA" id="HMVCIAN"/>
    <dbReference type="OrthoDB" id="2402916at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018571">
        <property type="entry name" value="Membrane_anchor_Opy2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09463">
        <property type="entry name" value="Opy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane anchor Opy2 N-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="480" mass="51411" checksum="E9A020A7BA55A7E7" modified="2023-09-13" version="1">MAHGMHPEVERTMRHIFKRCVQCPANETPTCPDCAKGEICSLIPQDCNNCAHMVCIANPNPAPKSDKTNVGAIAGGVIGGVVFMAVVVFFLWRFWIKKRREQQDLETEEWEEDDIAQQKHTQQFNAMRSDTASTRTKGSIANSILSRASNIIQIAYIPGVTNRNGSGHNSLLANTPVPPIPAAYRDNARGTTTPKSPLSNAGDALFFRPGDLRDSTYSDGSSIRSANNRYTQYTRQSITPSLARSSVMSDIYRDDATAEPMPPMPVQRIMRGAPKMVSVKSQGSSPSESPGSESAPSTVKVMMPGQASSNSSPSSNTGSFVKATPIVVGKNKGRFPIARQNSDSSLTPSAKHAPAVPSPLVETSTESGDEEEHARARRSLIQATARAADPAPLIQPLESPFFDASELQTAASSSAADRPNPYAAMSKTVGHQRAVRNDRGPGGLSAVIEEAAKRASQDRDHDGTGGKRDSSPFSDAHAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUZ4</accession>
    <name>A0A9Q8UUZ4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Piwi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767658.1">
        <property type="nucleotide sequence ID" value="XM_047911766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUZ4"/>
    <dbReference type="GeneID" id="71992496"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12618"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="326"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="611"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="911"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="925"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="971" mass="106449" checksum="03E8100DD95CC93D" modified="2023-09-13" version="1">MAGAQKDRVQKERRAAAPSSSGSSTSTSRTSGGAPSKSARSEVSRAGTSRTDRTSRSNAGGYDGNTDPSGPPMRNPSTAKPIIDPKNFDLSMAGWATVRSNDVSSSMPSRQAASKMGQAIKIGLNTYHVSQFPNIKVYQYDVMIGSGVEKRGLIRKVWNSKQVQAAVGDACIFDGNKLAWTAKKIDREVRLTIDMNVENERKNPKKEDTVRVSIRLTNEVAFQTLMAHLQGKAAFDNSCLETIAFADHLLRESPSRKYTAIKRSFFAKGQKRFDLGGGVEAFKGVFASLRIVHPGRLSVNLDVANGTFWTSQPLHKAAVLVCGARNDGDLVTTLQRGGERGRAGQELKRLRKVHVVAKHRGKDTIDDYCIERFIFADAKTHKVQVTDPSGNEVEMTLYEFFAKKYNIRLQFPGLPLVKATKGKNIVLPMEVLQIKENQRYNFKMDERQTSNMIKFAVTAPPERYTHIEHGLEMLDWANDPILEKYGMKIENKKTVVDARLLSAPTVKFGVGDAKPGTSGRWDLKGKKFLQPNTAPLKSWAVCVVPGRRGGKPDKTAVENFIKAFINSYQAHGGRVENKNPAMSLASSDDVGAWVTAAWNAAGNQSNSRPQILVFILPDKDSQTYGRIKRSCECRYGVVSQCVQYAHAQKCQPQYISNVLMKVNAKLGGATCKAVGQKTANGHFTVPTMVIGADVSHAAPGAQTPSMAAMTVSIDKLGTRYAALCQTNGYRVEMIATETINKDLKPMVQHWVQNVGGGKVPQVIVYLRDGVSEGQYAHVLNQEVTDMKNMLIAADQSAKNTKFIVLVGGKRHHVRFFPEKGDRNGNAHPGTLVETGVTTPFENDFYLQSHAAIKGTARPVHYHVLLNEPNMSNDQLITMLYEQSYQYARASTPISQHPAIYYAHLASNRAVPHDPKWSGSSDGVPSGTTQQVSGSQGQSAGKTGSSSGVPQDFEKLMAMPNQGSINTSMWYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV58</accession>
    <name>A0A9Q8UV58_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767883.1">
        <property type="nucleotide sequence ID" value="XM_047911703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV58"/>
    <dbReference type="GeneID" id="71992433"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12555"/>
    <dbReference type="OMA" id="ERRIGDW"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="42309" checksum="B7D7A5285AB21221" modified="2023-09-13" version="1">MAAYQNLRAQVSHQPSRSHCPIAFPLVSDIETTAKRFVGIESKCTNENMSKCHRQSQSPLFCIPAELRNLIYDYASLPDVHPSKRRCPPHCITLACHSFHTNLSWLQVCRLIWLEANAVVFKYAEPLFFRLYEAPDLQHFMRNLTPLNVEYLQRIHIGQEVFNLALDPTVLKYLEDTTLQLWPPEVTITLTAYPCFSSTEDVSDWIMQILTHQKFASTDKLQINIHVAEHQVRNIQSIAEVIRRERRIGDWEPLSSNKREEVRWLRQWGDSRPRFQRGSPVNMAYRTFNIDFRRAPGTGKVRLQKYEPGMDTDCWHLMPWRTIFPQSHPCQRTFSAQDLHAERYLRKWQAEDSLLKFVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW12</accession>
    <name>A0A9Q8UW12_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C-module-binding factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768899.1">
        <property type="nucleotide sequence ID" value="XM_047912711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71993441"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13563"/>
    <dbReference type="OMA" id="CRREGKM"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="6">
        <location>
            <begin position="175"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="705"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="801"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1050"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1320"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="736"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="808"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="859"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="922"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="937"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1065"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1106"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1124"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1186"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1222"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1237"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1249"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1357" mass="151338" checksum="DEDF7765200B5C6F" modified="2023-09-13" version="1">MPAQRPRASFEPIAPDFNLKALVESTPNFSYVDRISCDMIDQQGMAAFEKLVLLHVIVGGKPLVIDGFEDRLDPWTFNPKWLRDNSGDKVENARNLTAKENLPLTMGHYLKNMGLLTNQFFDKPGAYREKGRQRVYLKDIDCPQVWWDKLREHMPPALTYLNDSTGDIGGPGAQPDPHSTQPGRRLGKGIARAGDLMSSLPPDMRAENLMCYIGHEGTYTPAHREMCASLGQNIMVEASNNVSEDGKAEKPGSSIWFMTESKDRHLVSEYWLSVLGHDIEVENHFAQVVAWKKAPFSVYVVEQRPGDFILIPPLAPHQVWNRGTRTMKVAWNRTTVETLEMAINEALPRSRIVCREEQYKNKAIIYYTLQKYASLLSQAMGQAARMPRQDSDAFLYKGKIKQLFKDFKRLFDLYKQILLSEMFSPEDRDVPKNIEYVPFDSNVTCAYCRCNIFNRFLTCPNCKDLLGHQADEDGDPYDVCMDCYAMGRSCACLAGLKWVEQFRWKELASKYDTWRKLIIQLDGGQNDKSPQIIQEERRRYGKKTLAEVCKDQLKRRPFKDVKKPADEPKEDEESDEEIVVGDDGVVKKIQKKKSKAWLKNNVPCHVCCHRHPTWKMAKCTTCERSWCYGSLFRGWDKMPTEIMEDQDWSCPHCLGICFAGACRREGKMVPYEPKGTLLGHDTKKVADVRSVEALVDFSVSNLNWLRDDDPANRTQSRRFQKARAEADRNKNMDPSMELDEDDDQVDETQVEMEYSPTGDDGPIDPALGGTGAGPSSRRRQKQPAAELDEDDLARRLQEANSALPPPAAMMAGAPANGMPDGYAPLTQAGYSGYGAPPADMYGDPDASNSYHYPGYQRDGDDDSLEPETEQALRPFKKRRRSGRDGEDDGDFDEIAMSKGKKAKKPRLAAAGFRSYDLAETPDSASASRAKNEAQQQFEKEKERKALEKAKKEGRFIMLQAAMKGKKRVVKLSIPGARLAQLMAQQAAQAALTAGDDVDAEHEVEAGAAQTNGDDEDDNDLLLKSDVAPKKTPRDLQLQYAEKIREGRILTGNTKKALIPVEKDEDYGYRHRERVNGKRVDRTKDVPATAASKKEKRKSQGGRPPVEYEEVDVASDDDDFDANESGWNAVNGTAKSNRNRRSLPGYLQERHADDDPDMPDELPEGHRDKHHNALRSGRTGNPKARASDAAAQLQAETAATVKQGQVAGKAPGMRPNSSNQPIEIEDDGNSSDDDVDDAINAAANGDFGAQTNGTPVPSGSSKQPSSTGRPRGRPPKGKGVATTSPSSLKKNAAEAAVLEAQHMMEEDNRLAKLQVLEMLNDPNSPRADMSFSRAGGDLFGEDESDDGLDEAPARSMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWB1</accession>
    <name>A0A9Q8UWB1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769184.1">
        <property type="nucleotide sequence ID" value="XM_047912912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWB1"/>
    <dbReference type="GeneID" id="71993642"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13764"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF147">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF20684"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="295" mass="34132" checksum="39DAB4B8B4171699" modified="2023-09-13" version="1">MDLLRRNPDIHYADPQKELNVGIWTLYAGATGFLAARVGSKVTRRHGLWWDDYILLFAWCILTITDTIIAIEYATGYVSPEWDDRMHILINITSCGNLLGQSLTKSAFAVTLLKLTRGFSHWKICHGVLWFCICVVEWGRICDSPSYQVWYRLDFCLSKHSRNRFKEGGNYYNVVMDFVFAAFPWVVTYGLDMKRKEKIALCLTMSLGMVVAIESAIRTEWKFDGNKKDEWYFWRNAMSNIWYSSEVTGTVIVQCVPVLRPLVQDLHTSLRSKSLGSTIDEVALDNFEPHWYHAK</sequence>
</entry>
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            <dbReference type="PubMed" id="35471194"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="157" mass="17733" checksum="2FE35E6FD9207488" modified="2023-09-13" version="1">MKAALEMAMLRDRQPPPRQENEVMELHLETLCRAYVDGLNTRRLSLSDPVWESIAPWFKACLDFPTLDRNCPFSFAGYLEIFSRASSRRPSYYLKITDIVINVDGQSAQVYITMQSSGLHPGGLETVDASHLSFGFFDGEWLCVRLEILRGIGSGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWU7</accession>
    <name>A0A9Q8UWU7_PASFU</name>
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        <submittedName>
            <fullName evidence="8">PH-response regulator protein palI/prr-5</fullName>
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    <organism evidence="8 9">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4T7</accession>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8L4T7"/>
    <dbReference type="GeneID" id="71981994"/>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
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        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="142" mass="15639" checksum="ADD7096E2B5C9E79" modified="2023-09-13" version="1">MSLWTEYIGATQHECAVEEQHKQTRSTAVDESLLGPHLSSQDRRIAFQLPGKAEMLFAVSHPPDVDSRYGPDLMKRRSEKSPSGNAVLHTFQARTPASTMFPATGTDGCTPQYVSDHTMPSLKSLDRFSAHDSSPTGNYVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4W4</accession>
    <name>A0A9Q8L4W4_PASFU</name>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755193.1">
        <property type="nucleotide sequence ID" value="XM_047899995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4W4"/>
    <dbReference type="GeneID" id="71980725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00847"/>
    <dbReference type="OMA" id="QQYHCCE"/>
    <dbReference type="OrthoDB" id="10659692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="522" mass="59339" checksum="5E99141DEBA68041" modified="2023-09-13" version="1">MANLRGVARDAYEERIQKFMAKYGQQAQEVIKDLTTTTTTTTTRDTFEPTTTSSRYSHYGPTPTATSAVWDSAAPSILYQTQGWIAWFWEWHRKRWLGEMAWYTCCGLGVIMFWALILWALLRYIPKQQWDRAIQSVRWFFNQLSRPFNALAHGITWGFFRALGCVYDKPWVHEYRARRVKIWEKFRTLVWSLLSAATIFWLAYQLHFQQSCWVKVHELQHQGFHLPGWVYEASRHQHGLSIDGPGINGQIFEVPFTTTFHPTATEYRTATSTVTARQTFTKTIEVGGETTTGECQKTVHQVRWNAEPQTLTIHETLTLDSAPAIETVTIHERAEQFNAAPEISTVTNYLTGQGIEHDTITVTETATRYQRDGSQCRLTSTQQEIIANVTPTTVNLVRTKTSYKTRTITTTTPGGTLVRTSRIPLTLTITDTSVVAKTAKKVSTSMVYKASTTVAGGTIVRTTRLSHTTTVTETETSVVPGPTCALEHEEDHEEEAHVCEHVGKSIVYCKKCQQYHCCELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5L4</accession>
    <name>A0A9Q8L5L4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA cross-link repair 1A protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00574</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755627.1">
        <property type="nucleotide sequence ID" value="XM_047899722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5L4"/>
    <dbReference type="GeneID" id="71980452"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00574"/>
    <dbReference type="OMA" id="AQVHMHS"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12650:FF:000007">
        <property type="entry name" value="DNA cross-link repair 1A protein, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000038">
        <property type="entry name" value="DNA cross-link repair protein pso2/snm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="731"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="118"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="891" mass="98336" checksum="3F2C1FCFF49CE0F3" modified="2023-09-13" version="1">MFRKPRDTAATSDTGRPPSPPDTPAKTPFNLAVPPTVPPPTMATKAKPSKPVPLPTIGRQGLTASAKKSAATAKAKQNGKGNTSILSFFKKDDSNDGLFVGQSSSCVDIMDTVEQQSMAVSDMDDADDVRFNEAGGSVKRRKTSVERPIESEDSPRTPETPAQPKAKEQSSGKRVGPFFEESDSEQEEEEPQAVIGVAQGDNDGIVAGEMPQQASPRRSEINEEVAQTEKFSIGTASARPALMKEETSFGIDLDAFNDFDEGDFDEHPFEEGDEFRERRYMEGQARLEDEDAENDYDPVPQDDDQSVSPDGAATCPICSIGLSGVNERDAGAHVNNCLDGNPTPLPQKSGPGRPATIPKSEPSYSRPVRPAKPGQANPFELGKPSTSGGSAFNKLMSGHAENAAWSEAAASEHAARGKPSYTRTCPFYKILPGLFICVDAFRYGAVEGCKAYFLSHFHSDHYVGLTSTWSHGPIYCSKVTANLVRQQLRVDPQYVVPLDFEAPFEIPGTKGVKVTMISANHCPGSSLYLFEKTVGKKQNGEPRLQRILHCGDFRACRMHIEHPLLMPNVRDRLAGTTREQKIDVCYLDTTYLNPKYAFPSQEVVIEACADMCVSLSKHTPDDSDGWEQMKRQRAGEGMTRFIKRESHPEIKEEALDEDTASDLKVERNPHASQQILSSVTDQKARGRLLVVVGTYSIGKERIALGIAKALESKIYAPASKQRIVAALEDPELDSRMTNDPREAQVHLTPLFEIRAETLDDYLKDFFPHFTRAVGFRPSGWNYRPPNSRFTDSPLVQTVLHSDNWKSTYSMKELTPQRGSTSRASCFGVPYSEHSSFRELTMFCCALRIDKIIPTVNVGSAKSREKMKAWCERWAAERKKNGLYKLPEDGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6X3</accession>
    <name>A0A9Q8L6X3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter G family member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00447</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756358.1">
        <property type="nucleotide sequence ID" value="XM_047899595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6X3"/>
    <dbReference type="GeneID" id="71980325"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00447"/>
    <dbReference type="OMA" id="MCVNGFM"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001305">
        <property type="entry name" value="ABCG transporter ABC superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052215">
        <property type="entry name" value="Plant_ABCG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48042:SF11">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="25"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="627" mass="69237" checksum="3C358CDA88D5721B" modified="2023-09-13" version="1">MSDIEKMIGGDYAQLTNTNIRSFGWKGVTVTVKDRQSQQPKTILSDINGIVKSGELLALMGPSGSGKSTLLNVLAHRTASLAASVKAAIYINGSAANPKTFRRISAYVEQEDALVGSLTVRETLNFAARLSLPKTVSKLERIQRIEALLTAFGLQGQANNLIGTPIRKGISGGQKRRVSVAAQLITSPKLLFLDEPTSGLDSAASFEVISFVKDIAKKHNLIVIASIHQPSTSTFAMFDKLLLLSQGGTAYSGPVSEVQPYFDACGFPIPLYMNPAEFIIDFVNTDFARDRSEVDQQLNMVHSSWHKSRLATATVTELTDEMARNSMDTDVNAEFKDESAGAIAIPLALIHRAFIKSYRDIIAYGIRIAMYMGLAVMMGTVWLRLNPDQGNIQSFINAIFFGGAFMSFMAVAYIPAFLEDRALFIKERANGLYGPTSFLVANFITGIPYLFLIAMLFSIVAYWLSNFRPTAQAFFTWVMWLFLDLIAAESLVVLVSSLIPIFVVALAGTAFANGLWMCTGGFLVPPQTLNPFWRYVFHYIDYQSYVFQGMMVNEFGQRNFTCGMDSQGECSCMYETELAHQCMIAGTGVLKNYGYKTGETGKWVGIMLGIILGYRILCWITLYLRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L706</accession>
    <name>A0A9Q8L706_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_01595</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756270.1">
        <property type="nucleotide sequence ID" value="XM_047900743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L706"/>
    <dbReference type="GeneID" id="71981473"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01595"/>
    <dbReference type="OrthoDB" id="1741594at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051751">
        <property type="term" value="F:alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO11904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="387" mass="43264" checksum="9DC4E5FA3B16A420" modified="2023-09-13" version="1">MARHRGFWRPSIVFTSSILFRLALLFYGRYQDSHSAMKYTDIDYLVFTDAARYVAHGRSPYDRATYRYTPLLAWILLPTTWGGLWFEFGKALFAAGDVVAGWLIFRILRTDGMPVGRALKFASIWLLNPMVANISTRGSSEGLLAVLVVALLWAVKSRRVIVGGCLLGLGVHFKIYPFIYAFSIAWYLDGSNDRTESTERSVAGSVLSLINRDRISLAVSSLTTFMGLNAIMYHEYGRPFLEHSYTYHLTRIDHRHNFSVYSTILHLSSLESLDNGFQAESLAFVPQLLLAVIAIPLALAKTDLATTMLAQTFAFVTFNKVCTSQVRWVISHDGAELIVRVVLSMVHGVPAILPATLIPFETACKRPSRTRFLGRWSSFLAAAGVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L748</accession>
    <name>A0A9Q8L748_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">feruloyl esterase</fullName>
            <ecNumber evidence="2">3.1.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_01807</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.1.73" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756448.1">
        <property type="nucleotide sequence ID" value="XM_047900955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L748"/>
    <dbReference type="GeneID" id="71981685"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01807"/>
    <dbReference type="OMA" id="HIGDEYC"/>
    <dbReference type="OrthoDB" id="424610at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF2">
        <property type="entry name" value="FERULOYL ESTERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="232" mass="24501" checksum="8BE0FF00FDB49D7E" modified="2023-09-13" version="1">MPSSSELPAPPLEHGTDASMARLHRKILSAVCTLVTFARAISRSPGCGKTLPATTKTGGLGSSNNISLTTSNGLTRSYLLHIPTSYSKDVPTGLILSFHGRGQSGAHQEKLSKFSDSSVNPDMLAAYPNGVDKQWQGDPAATTDDVPFTLAMLKHIGDEYCIDLDRIYAAGKSNGGGFALNVLACSPVASTKIAAFAGFAGAYYQEKDVKHCDPESVRITCDPGRRPVPIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7N0</accession>
    <name>A0A9Q8L7N0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UV-damage endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
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                <person name="Chen L.H."/>
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        </source>
    </evidence>
    <sequence length="1113" mass="122703" checksum="B71D352DE14D30F7" modified="2023-09-13" version="1">MNAVQEPAYQTGPQGGYDRPQNAGGQYYDQGQERNYDPRYQPRAQRGPPPPQHSAPRAHPPPQPAPYYEDPRAAPRQNGYPPQQAQRPLRDVYPQQNGQYDQPSAPTNGDVSNHGQAPPQKPGKMSMEEWKRQEKERMKKAALSPQTMPFDNAFPVFGNKKDDRSGATSKASNQRGSAEQRPHTAGGQRSGASQEDSYQQPQGRRPDIERHQTAPQYNHAAQHNNQHYHQHTEPRPVPQRQISHEARTPMGEDYPEQWPMVSGQTPPKPSQDYQPAAQDRPSRYAPDARDQHQQGYYQTDRGTESQRMPNHRQPPPPAAMTHQPTNYANGPMNPADVVPRPSTAGGPRAPRPNDNGEQFRPPDFPQESTRSLPQQSAKPWMQESQSRPESLGDIYDDYSSSPPRQQIQRAPTTRDEEIEAEMPDFDSAAPGGTSLAHKRTQLQDDRSRGAPLKMAHPPMQRMGTAPPQMVNGHRQPPGQLPQSDSAPDLGYNQNGYGPRPGTAGPGSRGPPRRGMTDPRSAGSTPTSAHPPPQRQYDIPCRNGPPAGPGYQGDGPLPPPQAPFATEPQIRRSLDDSRGPPHRQGPPHPQRFPPNGQPPRGPYPPQQRPDLDRNQTNQTVWSDPGQDRVGSAPPSQQGLRGPPGGAPYGAAGGAPLTQQRSAPDNQQARHSNPDTLPHHPVPVRPGHVAPGQGPPAGPPPVRNYNPNGTGANGAPHQRQPSADHFAQPVTGQELQRLRATVDNPPHSPKQALLLVKKLVEAAAVLIVSADPKQKAKDREMYINEAYKRLKKLVANGYPEAQFYLADCHGQGMMGLEVDTKEAFKLYQAAAKAGHAQAAYRTAVCCEMGPEEGGGTSRDYAKAVQWYRRAAALGDGPAMYKLGAVLLKGLLGQQRNMHEAVTWLKRGAERADRDNPHALHELAGLHESSNTNPEVRNKIPADDKYARDLYMQAANLGYKFSQFRLGQAYEYGILGLQIDNRNSIAWYTKAAAQGEHQAELALSGWYLTGAENILEHSDTEAFLWARKAATAENHPSVGKAMFAMGYFSEKGIGCPANIEEAKKWYGRAASYKFPKAVERLEELRKNPGRKDKKIEKDSKLVRNNQKQNEENCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8U9</accession>
    <name>A0A9Q8L8U9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757293.1">
        <property type="nucleotide sequence ID" value="XM_047900791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8U9"/>
    <dbReference type="GeneID" id="71981521"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01643"/>
    <dbReference type="OrthoDB" id="3944708at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="34648" checksum="49211DA00348551B" modified="2023-09-13" version="1">MYHGGFRSVSLVLAATFGCRESDIGVTSSVGSSWALLLRHQLYQRQLLSFDETCLLVRLLIKATMDPFQQQTFFAEPHWQYPNADATFVPVAEGQEMTYFHPPGHAAYPIEQSDSTAQVQYMSEQPAPRVNEAQIFPIPGGVPATTYPIVRVRRPARRDLTDTDDGERREKIRRTRTACEECRKRKQKCDGGEPCHPCSEQSTKCCYRDVPPTKKDDTMDRMLQLAENYNKTLACLTKDLDVMSGTLRSIEQRLEKSWRAESGASGGSVEGVRLGYRQQARVSAEQSGREQMFKARPSSTRQRDHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L904</accession>
    <name>A0A9Q8L904_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Serine/threonine-protein kinase SSN3</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Cyclin-dependent kinase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Serine/threonine-protein kinase ssn3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">CLAFUR5_02224</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="25" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756779.1">
        <property type="nucleotide sequence ID" value="XM_047901372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L904"/>
    <dbReference type="GeneID" id="71982102"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02224"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 25" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="71"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="436"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00040708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="UJO12413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="475" mass="52356" checksum="77AE5B5E1AEE8C24" modified="2023-09-13" version="1">MSSPPSAGVMGPPSAATGRNAPAPASAGHPQSQGLKRTAQAAFEAEAPETPPLVRMNATPYAPQRHINDNYDIVGFISSGTYGRVYKATSKRGAPASSTAQVQHPDGRTIEAFAIKKFKPDKEGELQYTGISQSAIREMALCTELSHPALIHLVEIILESKCIFMVFEYAEHDLLQIIHHHSLLPRTPIPASTLRSCMYQIFSGLLYLHQNWVIHRDLKPANIMVTSSGAIKIGDLGLARLFYKPLHALFSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKQDSKKAVPFQRNQMGRIGEILGLPKKADWPLLPAMPEYPNLQTVNMHNPGVNRPLSLEKWYRNTIQNNNYGGPTSPPPDDSALDLLKRLLEYDPLKRLTAEKALEHPYFVGNDGKGRPPSWNCFEGLEAKYPARKVSTEAHEISTGSLPGTKRSGLPDDSLLRPPGKKMRGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L911</accession>
    <name>A0A9Q8L911_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757511.1">
        <property type="nucleotide sequence ID" value="XM_047902538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L911"/>
    <dbReference type="GeneID" id="71983268"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03390"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="766" mass="83844" checksum="79A7D25E8127529B" modified="2023-09-13" version="1">MPNYVSHVDTDADIRISNRGLDFNHGASGSSRAGPVGGDTHSAKTSAQMSSAHKAPLTTHPDGRGDGIGQSDSIPPHVSRSGKSISIQEGLLRVPEGGQGHVRRPVETSILDLDTPLNTFGELSSSSCYYEPQGELLQERSDQRSLQGDFTIPQPVGPSHFTSAFATDNLDKNDGFAIPRRPSGQTTTVAGAKRKSSSDQLTEASTSANKRTMRTMSESGDEAVSPSDVQTPAESVPSQGGQGNRSRSDADTPDPRPRAHTVTFESMRPPLSNGGPAGGARRSVTDPNVSMLLPARKVFPIQIGDKLFRLSGASISSDAPSYFSQFFEEQLRQNEGADNVRTLYIDRDPATFEDIALHLQGYHIEPRDGPHFVKIFADAQFFSLPRLTAQLFSSTIYIRIGDSEFQIPRDLFSNPGDSPNYFSLGFSAFFTTPNDVFPGLTERSLLRPPSILPPSVPGRSAKTFADLLHIIKGYPVEIRSDEHRAELLRDARYYHLKGLEQRIIPHTISYNLARRRTEILIRLEDIRQSGVSFMADGTPDPGSTAPSPVSTTPSSNAPASPGWVYYHRPYVDTEAYSLIIEITGEESTFLSVEPRGSLPNARMCRATFFKQTLSRITSLFNVVANKMNLPVIHPLGLMMMERGAGVASLPVSPSNTGMSEERAKCRIGADADVFVDGKRWTPTGEQSDDQEDEGTRTRSKKRKSNEDDDNEGEEWIVRKSQWRLRVQPMNGGVQSGRSGMEVILGAVKVEAFSSERGRNEERGFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9Q7</accession>
    <name>A0A9Q8L9Q7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757727.1">
        <property type="nucleotide sequence ID" value="XM_047901706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9Q7"/>
    <dbReference type="GeneID" id="71982436"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02558"/>
    <dbReference type="OrthoDB" id="3447202at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11616">
        <property type="entry name" value="SAF_DH_OX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048423">
        <property type="entry name" value="DRL_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37850:SF3">
        <property type="entry name" value="BLR7815 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37850">
        <property type="entry name" value="STRU PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21135">
        <property type="entry name" value="DRL_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="1">
        <location>
            <begin position="365"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="50199" checksum="DA573C866929B22B" modified="2023-09-13" version="1">MTSLSTKLAEREAAGKPIQVGLIGAGKFGSMFISQSHRTPGMRLAAIADLSADRAKAALKRTGYPEDRYDAAGSMSIEEGIKTGKVAITQDSAAMIATPGIDVVLEVTGSPSAGIRHALLCCEHKKHIVMINVEADVLAGPLLARKAREAGIIYSMAYGDQPALIAELVDWARTAGFDVVCAGKGTKHLPAYHWSTPDTVWDHYGFTKEQLATGDFNPQMFNSFLDGTKSALEMAAVANGCDLTPPSGDLLFPPCGKHDLPRTLRPKEDGGLLEKKGTVEVVSCLEVDGRPTFDDLRWGVYVVIEAPGEYQRECFAQYGLQTDSTGRYAAQYKPYHLIGLELGVSIAIIMCRGEPTGQTRTWAGDVVATAKRDLKAGEKLDGEGGFMVYGKLLPAETSMDIEALPVGLAHGVSIKNDVKKGQGLSWKDVDYSEDNQAVAVRREMEAIFRKEFQEKKGKTNGVNGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAC3</accession>
    <name>A0A9Q8LAC3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758143.1">
        <property type="nucleotide sequence ID" value="XM_047902300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAC3"/>
    <dbReference type="GeneID" id="71983030"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03152"/>
    <dbReference type="OrthoDB" id="5308957at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="14"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="570" mass="63547" checksum="DE3038193EA25D95" modified="2023-09-13" version="1">MANMSDCSITRGPSAEQWRTHRDEITAMYLRQSLSCMRKHMDQQYGFRASKRMFDARFKSWGVQKNLRRADKEKFIHGMTKATSFSENDMKKVKRFLTAQQRLDRSKSLSSSPGRGYGQSSSEASSPHTSQEHTPSSSDQSIVDGSPSSEAITSPQGSQNLSQRRLYNPLGVDTILPSERLDRLSLAATFTTPSGTSFRKDNNDDCIPMTMQLSSSAADRNVELLWTTMDHFISFKIQYTPSNISQHMFLNEGATDTSRSFWDRVENAIYQSKIGNTEGLAVPAFNDAKRLLQSLFRSGQVSLDFVRKALYTLSPTNTVMCSESRTELMKLIREYAAKGLGVDHPVTKVCAILLADEESSDLSRRALLKMYEMISDGFGDHGESHPASCKVMDSVITLARRTGEQELRKVSNPSPARRARELATAISLAGDAHQLAIIQFGLDSVEARQAAYTLAELYTVTQDHIQAHALRLEIVQRGSWSKIGPSRSTICEDAISAYTMESIAEHCEKENDYQGSTTWLARADSIASKIWDDSNISRTHISNKLHNACARLGESMISASAWRSQSHGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAN5</accession>
    <name>A0A9Q8LAN5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ribosome biogenesis protein bms1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_02904</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758253.1">
        <property type="nucleotide sequence ID" value="XM_047902052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAN5"/>
    <dbReference type="GeneID" id="71982782"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02904"/>
    <dbReference type="OMA" id="KLHVPMV"/>
    <dbReference type="OrthoDB" id="10260897at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01882">
        <property type="entry name" value="BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000105">
        <property type="entry name" value="BMS1 ribosome biogenesis factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037875">
        <property type="entry name" value="Bms1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="66"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="405"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="572"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="635"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1099"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="494"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="643"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="672"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1099"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1152"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO13887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1172" mass="134010" checksum="AC2B2C73F0FAAF16" modified="2023-09-13" version="1">MLGEEQTHRAHRPSKEKKAKDKSQPNPKAFAFAAPGRLAKQAARSHDVKEKRLHVPLVDRLPEEAPPLVVGVVGPPGVGKTTLIKSLVRRYTKQAVSQPTGPITVVTSKKRRLTFVEGPSDSLAAAIDMAKVVDIVLLMIDGNYGFEMETMEFLSVLSSTGMPGNVFGILTHLDLFRKQDTLKAQKKRLKHRFWSELYQGAKLFYLSGVINGRYPDREVLNLSRFLSVMKNPRPLVWRNSRPYALADRMLDITPPTLIEEDSQCDRTIALYGYLRGTNFPSNDVRVHVPGVGDLNVDRVESLPDPCPTPHFQQLREKQDPSTKKRRRLGDKQKMIYAPMSDVGGVLMDKDAVYIDVKSNTFDAEEDDAERGLGEQMVVGLQGERRLLGEDDQGIALFDRGERLRQLDDEEDVQDTGRKTARKPTIAHREGDEDDLEDEGLESGDTDDEADLEELQQASTKLSKSKKDKDKEVEGDIAFADSDSDLGSLSSVSDQELENDPDAENEDEDEDNEDNEDDEDDDDEAAPRWKSNLAERAQHLHGRQQPYRVAELARMMYDDMLSTAEVVKKWRGEEADGSDADDEEEQEDVFFKRRHHGNTDTDDDRMIPRYDYEELEQKWTDEDNIEAMRKRFAKTRATGANADELGEGEDDEFEGIDEDDDEGDGAFEDLETGESHVAEQSLEDEREKNARKKEELKSRFEEEDREGFLNPKNTNREADGKAEEQEFGEDEWYDQQKAALQKQQDINRQEFESLDEASRVRAEGYRAGTYARLILSSVPYEFAENFDARYPLLIGGLQPTEERMGFVQVRIKRHRWHKKILKTNDPLIFSLGWRRFQTTPVYSIHENRQRHRMLKYTPEHMHCHGTFYGPLAAPNTGFCCVQSFSNSNPGFRIAATGVVVNVDESTEIVKKLKLTGHPYKIFKNTAFIKDMFASALEIAKFEGASIKTVSGIRGQIKKALSKPEGCFRATFEDKILMSDIVFLRAWYPVRPHRFYYPVTNLLQGAGSNAWEGMRLTGQVRAAQNIPTPQLKNSKYGKVERQERRFNPLRVPKKLQADLPFKSQITQMKPQKKETYTQKRAVVLGGEEKEARRLMQQVMTLRKEKVEKRRAKQEERRQPHRAKVAENESMRKEREKRERDEFWRREGKKRKGWSEGGDGGGGGGGGKFKKRRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAQ9</accession>
    <name>A0A9Q8LAQ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758283.1">
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LAQ9"/>
    <dbReference type="GeneID" id="71983288"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03410"/>
    <dbReference type="OrthoDB" id="3649502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="20616" checksum="2A8F5006C777EDA2" modified="2023-09-13" version="1">MDHILANKHTQDAMDLDKMTFEDLEIYKSQLDLNARSPLFRLPSELRNMIFVLAMHGELQERKRSSRHATMFKQPAFFAANRQVKAECTGLWFADVLIWEEFDFTSKKWTRMSTDAVREICLAKTASGRCNLVTQSAYCDVIRTRDAVEGSRSICPRKGLVRIDNGMPLPQLRWWVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC15</accession>
    <name>A0A9Q8LC15_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor 1-gamma 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758972.1">
        <property type="nucleotide sequence ID" value="XM_047901633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC15"/>
    <dbReference type="GeneID" id="71982363"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02485"/>
    <dbReference type="OMA" id="TQYFSWT"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Elongation factor 1-gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="253"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="414" mass="47410" checksum="C5DFD34C4514D254" modified="2023-09-13" version="1">MGFGKIYSYEGNPRTTAILAVAKANGLDLELVHTEPGKVSDDYRKINKLGKVPTFQGQDGYVLSECIAIAIYLTSQNEKTALLGKTKQDYASILRWMSFANTELLPGLAGWFRPLLGKDAYNKKNIEDSKKRTQNNIKVLEDHLLVNTYLVGERLTLADIFTAAIVARGYDYVFDKAWRAQNPTVTRWFETVANQEIYKAVAGELKFIEKAIPDTPPKKEKEDKPKAEQSKKQEKKKEVAEEEEDEPVEKPKAKHPLEALPKATFVLDDWKRKYSNEETREVALPWFWENVNFEEYSIWRVDYKYNDELTMTFMTSNLVGGFFARLEASRKYLFGAASVFGVTNDSVVRGAFVVRGQEALPAFDVAPDYESYEFTKLDPTKKDDQEFVNDMWAWDKPIDVNGKPYEWADGKVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC68</accession>
    <name>A0A9Q8LC68_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1760-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758910.1">
        <property type="nucleotide sequence ID" value="XM_047902954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC68"/>
    <dbReference type="GeneID" id="71983684"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03806"/>
    <dbReference type="OMA" id="MQLQPED"/>
    <dbReference type="OrthoDB" id="5396786at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040347">
        <property type="entry name" value="YBP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020:SF1">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="95"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="75048" checksum="378057BCB633F49E" modified="2023-09-13" version="1">MAEDDNPLIKALPPASDYYTYLTIIEYNLTPENLPVLHKVLQDEQLTTNIGWDLVHLLVPLLPESEECLKDIARLGNPREVILKVTESLRLIEYDGIEEDEPQSDEGEDGSADEIRSKADNTTYPLKTAATTAGGSPAAMVEVPPPLPLPVNQFVALLSMLAVLHPRIKTKYPTRFLSATLQAILASFSNAPAGKHREEMVVAIVKTVKSVTGIQRPTLPSRKSSGMLPSSVARGSAPAADPEGSAVSDKSLEESEMQTKLLQAFVTHVLEEYMLNFSSYDGVPGMAWCSRIMEKVHPERSIPDAATFKDRFANEERLHRRIDAVGQLANLAQDLHITDEQLLEAAITVEKSAEGDAGDEIEPPANAKDIPLSRLGSLMLYAAREVSTILYDRPRASSPAFELFPDHQELLKHCLAPADMGTGQLGTEPEALIDAMLSLGLVCLERDDVGDPGTDEQFNEYLQVIALLSSNCPNPNLRGHAHYLTTTVLRSQPDEQVRLSFIRDTLEHCPFENLKVSAVGWIKGETIEASPPTPIAGHSHPHENENSNVTTTSIFAKPLALDSLAPYLFPSLHADLLTAPIRDAWMTFQTNISFYLASLNFLYLLLQAKHIHGSLDVQDLWTNNDVAGSFLQPLRDAKKRFLQEMESGCALRDEKSPEAVAELGLLEETVERVTRAVVGLNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC96</accession>
    <name>A0A9Q8LC96_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758940.1">
        <property type="nucleotide sequence ID" value="XM_047903039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC96"/>
    <dbReference type="GeneID" id="71983769"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03891"/>
    <dbReference type="OrthoDB" id="3634414at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045702">
        <property type="entry name" value="DUF6060"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19535">
        <property type="entry name" value="DUF6060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040290783" evidence="1">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="31096" checksum="99BAE5B037C0D9CB" modified="2023-09-13" version="1">MAFLTSLALLQAIQLATAAPAPVFEISKRQDPSGTVDACKGSDCADCPLYFSTGTGYPECTYYDTQQLKDKGYPSDENGMVDVFFSAPPLVDNTFLIQFCCGTSDCTAAGAPTKRSPNPANAGLGKRGLSTLLLHDRNGTVIEPQTFAPTAVKERTIQKRDCGGFTATNGPYTKAGPISIILDEVTCGPTESCSATESKTVEQSFSVDVGVSVGDPFGIISASIGITWEKSISRSFSAQYMFGAGETGYVTFIPILTCVDGYYTGDCDDSGKQITACAASSSGGAMAGDIRGVVVRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCC0</accession>
    <name>A0A9Q8LCC0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0653 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758970.1">
        <property type="nucleotide sequence ID" value="XM_047901637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCC0"/>
    <dbReference type="GeneID" id="71982367"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02489"/>
    <dbReference type="OrthoDB" id="5876637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40644">
        <property type="entry name" value="UPF0653 PROTEIN C607.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40644:SF1">
        <property type="entry name" value="UPF0653 PROTEIN C607.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="35173" checksum="D8D94EB982000A1C" modified="2023-09-13" version="1">MPHKHTRRRASGKANFDLAPSQVAKPLPAFEKSEKAAPKGKKAAEPSLKRKRTGTSDYKQDDTPRAFARLVQLRDGQKQRAGLDDGESRKTKKKRKTDEAGNDEPELTKKTLPVDPQTGEQLKILPGERLADFAARVNQALPLGGLTRKGKYKDGPKERQTKTEKRLHKMYAEWREEETKRKERLEELQEKQEEEDEEKEAEYGGQRVDLPDSGRKAKRKRMVGEVDDADDDPWAVLKTRREAPKGLNDVVQAPPTLKVIPKEKFKVRNGAKVNVANVPGAAGSLKRREELGEARQEVIERYRAIMKSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCD1</accession>
    <name>A0A9Q8LCD1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759251.1">
        <property type="nucleotide sequence ID" value="XM_047907378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCD1"/>
    <dbReference type="GeneID" id="71988108"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08230"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="15051" checksum="BBD6C8910E69E5A0" modified="2023-09-13" version="1">MANHRILVFDLLAPRHRGDDGRVRSHSGGLATIRREARERNRKHSTLSGPVTYDAEESLEAGERSSLLRLGGSVQAGKQKGKVVKAAFYGVQVFYSFFIMLLFMTYNGWIMIAVGVGAFIGYLMFSGSPPTKSAACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCN4</accession>
    <name>A0A9Q8LCN4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonohydrolase oryL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759135.1">
        <property type="nucleotide sequence ID" value="XM_047907002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCN4"/>
    <dbReference type="GeneID" id="71987732"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07854"/>
    <dbReference type="OMA" id="NVLPYHF"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040209217" evidence="1">
        <location>
            <begin position="20"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="2">
        <location>
            <begin position="197"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="424" mass="46316" checksum="FD4993BBF023BD28" modified="2023-09-13" version="1">MRGFAVSMSLLSYLTTAISQSDPPGVSSPIASTCGPSDKVVCLDRYASVLPYHFFRASGSDGEEGPAFSETSVPNDTSFGLIADADFIVFDQKRGLEVLGANPTYEYVFEVSEAVHEAPVYVPALNKLFLSQLAPPAGYLPQLVVDLNRDSPTLSEYLSDPPVYAPNGDTFYNGLIYWAASGGNRSIGGTEQRIGVRTLDPLTNKTTTLLNNYYGYYFNCVDDLFVDPRDGSIWFTDPQYSWFNSLTDTAPQLKSASYRFDPSTGETTIIEDTLSQPNGIALSPDGKHVYISDTGAVAGSIVIQNGTPFNQTGSRAVYKYDRVDDGKHLINKRAIYYAIDHVPDGLKVAQNGYVVTATGRGVDVLDAFGSLLVRVQTNYTVQNFAWTGPDLTEFWVMGQGGISRVRWDLRGQDLAARGEVEDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDD4</accession>
    <name>A0A9Q8LDD4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07759</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759676.1">
        <property type="nucleotide sequence ID" value="XM_047906907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDD4"/>
    <dbReference type="GeneID" id="71987637"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07759"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="341"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="10">
        <location>
            <begin position="383"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO15310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="501" mass="55562" checksum="6CCC76FA069E4D79" modified="2023-09-13" version="1">MWLPLPDFLLHAFQSTFTAEPPPGLIPIPGTKPLTIEAVLCPVLLYYIALLLLPPPPPPTVASFHIGILRNALAICAAYLFFKLPLAYHVPQSIGLTYQLGLVGLYGGLRVLDAFFVSFYGFGHVPRRVRYYHNTRPETPRAEVAPRIWSDGGGPMRKASLSQPAEESRKVQANVSAKTTGSDALGVPKRPGMQRGVSQSDMLENMTSQLYSDILSRDESYTTMLKRLIDGPKPIPVDEIAVTEDGYPHGFADRAAWALELELSMRGVGFTWTTADVRHTKKTWLPTPQNRLHSILVHVGPVLVVAWAVIKTMYVNRLAPMSERELPPSSPFDELSLPEQYLLTAALGAFLMAAFSLGHSIFAIMCAPLAPSPLAFFPQLYTTRVWDIASARGFWSYGWHRLFARLFLVWGVWPGEWVERKLTGESPDERADVGKVLGGFLSSALVHSFCVRGTLGGKWSDAAGEAWLFALNGVAVIAEEGVRRSIHRWRKNHHQAESQWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LED8</accession>
    <name>A0A9Q8LED8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760247.1">
        <property type="nucleotide sequence ID" value="XM_047903170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LED8"/>
    <dbReference type="GeneID" id="71983900"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04022"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="67" mass="7432" checksum="7B3027EFF2CAA24B" modified="2023-09-13" version="1">MLYARTRRVSESHSAHSHAAAAVHDRQHWLAAAAWPSKMLNPVSGSTSPTKTTISGFETNMTSRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEV4</accession>
    <name>A0A9Q8LEV4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_04721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760480.1">
        <property type="nucleotide sequence ID" value="XM_047903869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEV4"/>
    <dbReference type="GeneID" id="71984599"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04721"/>
    <dbReference type="OrthoDB" id="3638832at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="604"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="895" mass="100750" checksum="3DD3CCAA76A7106F" modified="2023-09-13" version="1">MRQYFNGPGTWGFMIQSEETPASAVNADIGGTGIRVGLYIPVCLALLTLGLGNLHRDDTGAKEIGSAQLLTLFYLNFNAFKAATAGFKELTFPEVIVACMTIDFTAAGLHMTTSSKETLAARWFMGVSALNQIVAVVMIIAMLARIKHNYTDLPGVDIVWWSRINSHSGPSKAVWLYIAARCLILAHGLWLDARYSPLFHRLEKDWSYLAGADQEMERAKEEDETLVGKNAADESEYQYAVLPATVFGKWTEWLPSLLVAVTSTETLAARLRYHSDIQEWGQSAALVLAIAGVMHWAYVMGQVVREKLEQQCFLHWLFDTTRRLKVFDARSRHPVNYPRYAYRCEEGIDISDENLLRTAEANNMTAVRKLLRHDADINAVDQKQGMTTVRYAIRYGNVDFVRELTKKGANLRLPDNLPILLVAAQAGHPNMILYFLHKIEYASKLESREGRSALWSGSRHARRTVTSSIGPWTPDEAGRTPLYAAAEAGQYAAVRPLITHLCPPDQPSPGYSEALRRARSERCDKALRCLIACGTEISYLDNDGSTILHDAVRDCHAQEGSRLVTKAGQVNTTHQNLEDIYRDLECLAKTFKEFTRLVDVSDKDGRTPLSIAVRSDSDMSYNEHATKILLQLGANPFATDSDGKTPLLGYLEWRGQYISRCPRYHQDPVWAHPFVHALCPNLIHPAEPWNESLVAGLLDLPPNVMYWLVHETWIAPESQVGADRRPLIMEAVYTGKIGPVVALLTANPGSSYHAAVDIKQWQFHRAGHEENNYADPISARALESLWEETIEPRQRVVKTIVSGVLMLDWFDSSICILPNPNDHAADEINVVIQHDIYEPPKSIRRMNEDELSQRAEKKYHEIIEHLRDESYHPELLPDGIASRYIKKARVEHRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEX6</accession>
    <name>A0A9Q8LEX6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760488.1">
        <property type="nucleotide sequence ID" value="XM_047903914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEX6"/>
    <dbReference type="GeneID" id="71984644"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04766"/>
    <dbReference type="OrthoDB" id="2583188at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="50352" checksum="AB2F1441DDE8F253" modified="2023-09-13" version="1">MFQIKAATTTNENNTNNPCTLTASTEPPAVSSQYLPVSPVATMGHIKWPPSLLRTDILGEITDTSGRKIARDIGRAVWLGGNCYYAFGDTFCHDVKNEFCGVTNNSIAYVPDPRGAPTQSTYIDYAAGNPGAVRAFVGYTDGERQHSVDAQGKEKHDRVTCWSFGGIVEDREGCGSGWVFFDKMITVGSESGKHYGIGVARATVQPDKSIKLERPMGDETVFKEGEPKFGSISHLCDDDGFVYLMGGYDPTPGSLDMRCHLARIRRDADFTKRENYSFFCDSMDMKGEWRQQYDDPNQLAKMGDLDIQAQGKLFKTPDFAPEGRRYMWIGVNKFMAGHFYVGSAPAITGPWEVHDFGELPNDPHPYDGHSSGPKYALYPNPRASDLARGEMLCTWTDAAQMGGKVIAAKFWFEGDYERPPPPAPGVVEGGQGGHGAEHKHGDGKDKLKRDFLGGLLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFH1</accession>
    <name>A0A9Q8LFH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760977.1">
        <property type="nucleotide sequence ID" value="XM_047904226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFH1"/>
    <dbReference type="GeneID" id="71984956"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05078"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="11199" checksum="BC0279055660EB18" modified="2023-09-13" version="1">MSHRVTFTGMLSTCSTSEETLSFPFLIILALAICACCFLMAIFVVRVKEVCFDVEPESDNDIEALRPYDDDPSAHWVRPYNDTGEKEVLVVYEKERSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFI0</accession>
    <name>A0A9Q8LFI0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAAX prenyl protease</fullName>
            <ecNumber evidence="15">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_04939</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 15">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 15">Belongs to the peptidase M48A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="15"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760992.1">
        <property type="nucleotide sequence ID" value="XM_047904087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFI0"/>
    <dbReference type="GeneID" id="71984817"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04939"/>
    <dbReference type="OMA" id="FVIEEKF"/>
    <dbReference type="OrthoDB" id="360839at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000002">
        <property type="entry name" value="CAAX prenyl protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 15 18" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 14 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="17">
        <location>
            <begin position="40"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="16">
        <location>
            <begin position="228"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO16626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="462" mass="52139" checksum="77B1410C87E23768" modified="2023-09-13" version="1">MDFLRRLAAPLDNSAIPWKPILVTFALGEFALEAWLLSRQYRVLQRKTIPPQLKEEVDQKTFDKSQAYGRSKAKFTIASGLFGQLKNYITIQHDWLPYLWSLAGGFTLKYLPSRFQGEITQSLVFIFTMSLAETLINLPFGLYYHFVLEEKYGFNKQTLSLFFTDKIKGLALSLAFGVPIGSAFLKIIQKTGDNFFFYIWLFMLVVQLGAVVLYPTLIVPLFNKLTPLEPGDLKTRVEALAGKLSFPLQELQVIDGSKRSAHSNAYFTGLPFLPKKIVIYDTLLNKASAQEVEAVLAHELGHWKMGHTSKLLGISSFHLLYVFALFGVFINNASLYRAFGFVAERPIIIGFILFNDVLSPTDSLVKLGMNIMTRKFEFEADAFGKKLGYAKDLASSLIKLQIQNLSSMDADSYYSSYHYSHPILTERLKAVGWTSEKKVSDGKIDISGQKTFTVNGTPEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFJ5</accession>
    <name>A0A9Q8LFJ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760888.1">
        <property type="nucleotide sequence ID" value="XM_047904179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFJ5"/>
    <dbReference type="GeneID" id="71984909"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05031"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040334872" evidence="1">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="14092" checksum="129E159A67BB90F2" modified="2023-09-13" version="1">MFTTKTILALSAVAITTFAAPAPVLTTQTITATHDFGAGPTAFSWTTIFTVTPAGGVAPTPILAKQTVGEPVKPEETTVVGAPVKVEPTPIVVPSPSKPTEHLTTQTITATADFGAGRVPFTWTTTFPVAPTPLHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFP2</accession>
    <name>A0A9Q8LFP2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760914.1">
        <property type="nucleotide sequence ID" value="XM_047903165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFP2"/>
    <dbReference type="GeneID" id="71983895"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04017"/>
    <dbReference type="OrthoDB" id="3935813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="14847" checksum="3D3FED3059789C57" modified="2023-09-13" version="1">MPYYKFQVAKNVLTDADKDRILCIYLSSDPSAINRSKATRDFGAPSVEAFRKAISRMLKRLDDAGGKDGAMGKPMPKPKNSKKRRKSQPEDDSDEVEYTPTKRGRKAAIKIEDQKYDSAGEEDHINCECDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LG01</accession>
    <name>A0A9Q8LG01_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="924"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="955"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="985"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="995" mass="107886" checksum="F346ED888518B719" modified="2023-09-13" version="1">MPDPPEKRVVSIESLLGIAPCQPGRNAFAEADQAKHRYMQSANAFYALKYPPPPPTHPTLRDSNMTTMSQFMGDGPQSPPLNLGTTPDTTPQPTQRAFVEEYAEQRQHQTSGSTEERVPVFRPTPNLVSDEFGQQPPAKEVKFAEQASQLKSPKKNAFFAIFRRRTESAAAPPPAMADVSKSASNHMHPKAAAVLATNVHTPKRLARSPSKTKAFFRRRTSDASDMLTSLSPLKDGKSSKTAQHDEPPPRSQTSTGHYSATPRKPSLVSPSRHIASAPHSDAGSARNSSRNSTPHLGRSLATMDGHNQIPPTPPSKDTPPDEKAVRNVVDRKMPFLSFKNSTPTKTTGFVTVSEGLSPTKYGSYATRVGAKLVTQPSSHSLRASVVPGAMDRQTFEDVKSRVNGLGLAGMDMPAETHRQSQAAALMYSPSVYSPELGDSNWGRKSFATFERVEEEQGEGEGEEHGDNPCLPSSPLGLQGHKKRHSLATSTAGHLEVPAPQMLKLPSGHSRQDLQVPVNTAKTTESSATIEVAYPELAKDPSIASFMNLDPNTPKDATMLSSIEEVQGLYQNTPITTDGKRVMSSSLFYSPGDSPMPNHPSAQVSPLQPQVYNKHLETLPATVYTPAPKIRKAQNKLSHGHSVENLIDMYNNAYTPTTKLPPRKGSGEQSVYSPYGADSPTLKSEQRKASGDQPLYPFNGSASGFVPPPGISPDIPAQKPKHSNLFDNKPFLPMEGSASGIDREREDRRQSIDIDPKKSPATSAKQHVDGQQTVDNVTRMINERKKHLQDMTDNAQRMNARLEARLSASEGGGIPSDISGPIPTIMYEDDSGVEITNGKRGSPDSKYDSKKKRISTNFARDFYGNSPTSQRKVSPADTEASTIILTPNLPHGGFPRTNGVVTSSTLVGHSIAAQEDFASAPETRSSTSSIKPASASSAGAQAENGEVRELKAMIKQQQDMMQQMMAQMQQMSTSINSRQRTSGSPPDREDSWFNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LID7</accession>
    <name>A0A9Q8LID7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762309.1">
        <property type="nucleotide sequence ID" value="XM_047904883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LID7"/>
    <dbReference type="GeneID" id="71985613"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05735"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23777" checksum="D010A30A77D19BD6" modified="2023-09-13" version="1">MRPLPTQLSRQIRNPNLNKFTALSFTASQRTSYRTMSTDKGELKIENTNIQTAPGVDLSERQQTLVGSVLDLFAGRPSLAKLQLWQDEGEFIDPLTIAKGRKQYEAQWYGLQTAFSEIERLSHEVKTNGNPIEMDMKTRYVVKGIGKEQVIASKILIHQDGDKISKVEDRWDGKLPESSIAQFFQRVNANTVPLMVGVPKNAEEDAKKGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJE0</accession>
    <name>A0A9Q8LJE0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="6">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06011</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="6"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762059.1">
        <property type="nucleotide sequence ID" value="XM_047905159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJE0"/>
    <dbReference type="GeneID" id="71985889"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06011"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF83">
        <property type="entry name" value="DEHYDROGENASE (CYTOCHROME), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="346" mass="38022" checksum="A4BC58F48CFE56E0" modified="2023-09-13" version="1">MVSTNCSGTNAMRYGTMKDWVINLTVVLADGTVIKTKRRPRKTSAGYNLTTFFVGAEGTLGMVTEVTMKLAPIPQDTSVAIVSFDSIREAATAASSIIRSGIQLAALEFMDDVQMQVVNRHGSAAVRKRNWDEKPTLFLKFSGTTDAIKSDIGRVQQLMKPYNAGGFIFAKTKQEEQDLWAARKEALFTMVNTKPEGTEIWSTDVAVPLSRLADIIGKSKLPRIRTQLTCPVHSKEDCSKLGLFASIIGHVGDGNFHASMFFDPQNPEQKAAVGKVVHDMMDQALEMEGTVSGEHAIGIGKRDCLVDELGQTTIYFMKTLKRAVDPKWLLNPGKVFDLPEQRSSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LKD3</accession>
    <name>A0A9Q8LKD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762704.1">
        <property type="nucleotide sequence ID" value="XM_047904554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LKD3"/>
    <dbReference type="GeneID" id="71985284"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05406"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="215" mass="23768" checksum="F0115289B6EB2E06" modified="2023-09-13" version="1">MPLVSNGCVLKRSGRDRIRRSFFLRILSLLYTPHIPQFANLLLFDLALQEPFPINTSTLHQPRTRSQALRHLKSHQVNAISSKQTMAAITPEVSAMRSTLTTQPESTPMLPGLRLQRDTQASDVIPASPAPTPDVEKPMSLIHALQRRKQTSHLDFSDDDGATQGLGTPRTSTFEPFEDNISPACTKADGEQNCPIHFPVNGGGLFTAKEYLQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Y6</accession>
    <name>A0A9Q8P3Y6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase pytC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756665.1">
        <property type="nucleotide sequence ID" value="XM_047901214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Y6"/>
    <dbReference type="GeneID" id="71981944"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02066"/>
    <dbReference type="OMA" id="ETDAWAT"/>
    <dbReference type="OrthoDB" id="3621619at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="147" mass="16273" checksum="81C58B6F6E15827E" modified="2023-09-13" version="1">MAEKYPEAQIVGTDLSAIQPGAVPPGVQFEIDDWDDDWTYSAPFDFVHNRFNCTAVSNWSQICSKSFAALKPGGWIELADLTNPPHSDDGSIPINSQLCQFFIELTEGCSKAGRDLHAPKKWPSYVSEAGFTNIHERTFKVPIGGWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P451</accession>
    <name>A0A9Q8P451_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756817.1">
        <property type="nucleotide sequence ID" value="XM_047900815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P451"/>
    <dbReference type="GeneID" id="71981545"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01667"/>
    <dbReference type="OMA" id="AMSRLEY"/>
    <dbReference type="OrthoDB" id="4158258at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="15470" checksum="4473A50834610F03" modified="2023-09-13" version="1">MSASSNQNGASSDTASTASSLSNDTAFTTATLVNHNNNEQRTTLTGQPIPRQQYDSYTSMMYSQGGMGLTNAGGVNLLPPGYTDTSMVRIPIKVSDYAPQSPAPKKRSLLSKLEHDNDVEIKVVAMSRGDYLSTGSKVKTGTSGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4C8</accession>
    <name>A0A9Q8P4C8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757204.1">
        <property type="nucleotide sequence ID" value="XM_047899372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4C8"/>
    <dbReference type="GeneID" id="71980102"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00224"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="59" mass="6852" checksum="1F0658CD7EBA210D" modified="2023-09-13" version="1">MMGKVQIKLWMSGGDIGRRVLPVAWWRRYCQADDNVTCTARHKPRRGQHDKIQIDSITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Q0</accession>
    <name>A0A9Q8P4Q0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Serine/threonine-protein kinase Tel1</fullName>
            <ecNumber evidence="4 16">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_02993</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Chromosome</location>
            <location evidence="16">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 16"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757686.1">
        <property type="nucleotide sequence ID" value="XM_047902141.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71982871"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02993"/>
    <dbReference type="OMA" id="HACSVIR"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021668">
        <property type="entry name" value="TAN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11640">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01342">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="16" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 16 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0779">Telomere</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="19">
        <location>
            <begin position="1863"/>
            <end position="2470"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="18">
        <location>
            <begin position="2571"/>
            <end position="2884"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="20">
        <location>
            <begin position="2893"/>
            <end position="2925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="848"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2853"/>
            <end position="2879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO13320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2925" mass="324523" checksum="4232310A7A9C4393" modified="2023-09-13" version="1">MPRPPPAEVMLDEAIENISSSTVTTRKQGLADLKRILRLDSNDSRIRDLHEKTKLTLFQSLFQAAINDQSAYVKAKTPTLKSTTANRLSDIASALRLTAEVCVRSLTIKLVKAIIDHITESIYLQAGDLCEPLALDYAKTLRVVLSYQPHVEHLTKEWQGIVVACIGYLQDANSVAADPNGLDHGSTAGTINGSSYLSSRSINRESAGSQESRSVLRVVAEEAVSCLQLLTAAPNAPVKKMAHELMAALIDYLKTSSYTSRAHVEAFTAVNHVLSWTRIEDVKLTQEVTVQLMRLVRQLWSGKSHALEQMLITLLLLRPYILNGMCQESAISLRPELIGLIDAIQNEYQERDAKKQLGLGQLRLQFSATDSPASDEICTPLLTLRCVDANAESYWLIIYLLASFYNVMIGTTPLDADPDYETNHDSEADLNTRPRKRRRREDSLEALIEEASRGSPSSRTRALQVLTFLAQQKAFTPSQLRTIIGNISSSCSEEAGTVSSWALLAMAACASQAAATDDALGPHWLAAWQIASRSLSNASTCRSASFTLSVMLQLRLVPNDNIIELIQLLTLTMDINGPTLMADSVSLLLSRSLTAVQHVQPGAYAKAAESMALWLSQNFNPAKFDNKPYAAISSSWDASDVVALIASCLHQRTHQTQAPGFKVWHAPGRAWLLCQKHNDLVAYLLLSSSKDTSVTNPSLTATSPGPVAISTQLAYENAILKYLTAELIGANSKWAAGNASRSGFQLSRDQSVMLMKVCIALCCVSSCLTFRDLRGQQELKKEAYTLLESLQDYMSKASQDDTKMHDWLSTLSTAFCGLGTCDSNHEYQPPACERIVCRALVGSTHKQQHSSSHDFDDDDMDFEDSSNTQDSRQGKILAGAIELANDYDGTYSETAMRSNVVLYATAINAQDQSPSATAISAAVADFLLAQPDVSVLSSRVAITLLPKIGVTLNAADSERLLAYFMDQWANSYPHRRSEVALGTMLDVMSSLMTAWTDPSNKALHGLGVDIYDWFTMAVSVGFLSSNTQVKLASLLLELCHTDSEFGQTDNATSVRTNLFSTLSKGRIALQWSLAGRISTIFGLFVLSTHPAMFKDLRDSLSDDTEWLEGIAMRLLFLSKLAAAWHTLRRECVYALFETAGLVPHALEHTAHCLGELASKLPAKTPRKLFTMFAPQLLHSWLGTEHSITQLPFAAFQYTSLTDLLVSNQTEACAQILVRKSEEGMNIMTKALKLMPPGVIKGNFAKCAAYAISYDVLEPSNGPTTSEHDNRLKEIISKEDYRTYISQQFPTVLGYLYLHMQQDDPNDTWLVKSADFGQAAAALAEMKQYSYSKRMLPVPQQPSFRAKLLPNQIQRVCKRVGLQPTAPWTASSLTLAIRMLLDNIDETMGPLHFCIMIRRLRILVCMAGEVALAEFPLELLLHSLRPFVSDSECADDTMGILQYLMHRGRHYLEKHVRLLTGTTMLLILQMSRHARSKQSSTTQETQHANTVQKMQDFQRWLVRFLSETTNEPGTVAIDTGLTTALAQLQLPGNARAGSPENFILLFILKGWSSSTSQLSDTDAIEALRLLSEGFAPPPIVSDDCLGVDHEAVAYAQQLWECTQRLPANDHFRAWASGVLGRAFASTGTAPVVRRHGEVAIREKVDLSVARGTGISQATIVEHLNNLLFSKSRLEAGLADHTLRCLYQCPTDNGDNGDEAVALDNMLPSTIHAVVANGDYGYEPASATASIKIVVDQKLLRHVLGQWQSETLESWAINLVTTLSHWALVVPIVSTLTSIVQNVNGLAISLLPSIIHILLVKESDTGILRQELSATIAECLSETAEAMHSKQQFFLRVLLYLKSQPYLNETTKIDRLQWLDIDWSLAASAGSRCNMPTGALLLAEFAAPVPDANRRASARHSVSLLPQAKVSEDLLISLYQQLEEPDSFYGVQQTASLDSVLNRLDHEADGFRSLMFRSARMDSHMRSSHRLVDNDAIGMARSLSALNFNGLALALLKSGVGVSGTASDDILSAARTLQQWDITPPDTLNSDSATTFKVFQALSRASDARQADGILRSAVVDHAQSGFAGGSSMMPPKSWFHVLAMLTESHELITSADQTAMVARWRLIQARQDWMQMARYEDVKPLLSNRQTLFGMLCQNTMLQTALHLTKRQCHAFEAEALLDVSKFGREYSKIQDSISATSALDGMIEKYTATKLSVQAVVKSETASVLWDAGETSASIRMLRDTLTMADMEKQDIAVGRAGLLAQLGHCLAEARLEKPEDIMSNHLKPAIAHLKSRTEGSEAGDVFHEFAKFCDQELQSPSNRENLSRITKLRQGKQEEVDAIKLAIRNAKRTGEDRTTLNRSLRASQQWLDIDTHEETRLRNDRDKYIQQSLQNYLLALHASDEHDICVLRFFALWLENADDKEANGVVLKYLPDVASWKLVLLMNQLMSRLENEPSTFQKALQALLLRIFTEHPHHSLHHLFAASSIKPAATDTAMTSRFEAARAINSIMETRPAQKALNDRIFRADRYYKVLSELKPERSGKFRVKDYKEAYRVTTTVPTMLVPPATISVTLRPSGDYKDLPIITRFDSYGSVLGGVSQPKMLTATTSDGKEYKEIYKSGDDDLRQDAIMEQVFEEVSKMLRNHKVTRQRDLKVRTYKVVPLTTRCGVIEFVANSTPINDYLRAAHKRYYPSDYTDHKAREIINSVAGSGNDTRVKEFRKICDHMHPVMRHFFFEKFDDPDEWFEKRTAYTRTTASISILGYILGLGDRHCSNILLDTKTGECVHIDLGVAFEAGRVLPIPEMVPFRLTRDVADGMGVTGVEGVFRRCCEFTMDAVREDKDSIMTLLNVLRYDPLYNWSVSPLRAKRMQEAQETARRGGLEHENTSKKRESEAGEADRALAIVEKKLEKTLSTPAAVNELIQQATDEKNLATLFNGWAAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Z5</accession>
    <name>A0A9Q8P4Z5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757717.1">
        <property type="nucleotide sequence ID" value="XM_047901987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Z5"/>
    <dbReference type="GeneID" id="71982717"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02839"/>
    <dbReference type="OMA" id="WLHVPME"/>
    <dbReference type="OrthoDB" id="5593278at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="16459" checksum="72E2FB956D6797D5" modified="2023-09-13" version="1">MATPAAATLPAVNAFPAPFPAPSKSAAGEINGTHTEVTSIAFTDKFVITISQAGKLAHWVHVPIAAASADPMNPGIMSTSSSENNLLPMSHLTATTVLGGTKREDEVVGQTLATTIASAILMASPSEERLLVVGLGLNDAAGHFTGRAQFDEAVGLVLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5I6</accession>
    <name>A0A9Q8P5I6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 12B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758168.1">
        <property type="nucleotide sequence ID" value="XM_047901639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5I6"/>
    <dbReference type="GeneID" id="71982369"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02491"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="768" mass="83771" checksum="A36D74FEA40F6168" modified="2023-09-13" version="1">MSSNSVQSRFKRVFGTTRRSSSNSSVQSASNSTTNLAPSAATSPSPRPVNRTAPPSSSAGSIASTAQPSQQNNNVAQQASASSTSLAMNPNGQGNMPQGRPPSYQYANQGGNQLAAGGHPNAGRPTSPMPPPPINTGGGYPPHHNSNNNMYPAPNPPGYPMNNNAGGGGGGAYPYGGPPGGPQGPHSYNRLAEVEGSQRSKAQLIVGIDFGTTFSGVAFAFATNTEAKEDIIVEWPGAGTQTKQKIPTVLYYDQHQQVVGWGPDIAEALAPTGYPKPGVQKVEWFKLQLMLSGNTYIDPINLPPLPPGKSEIDVAADYLFKLRQAMRNQLQKTLGEVFNREERNIRYFLTVPAIWNDAGKAATRAAAIQAGFLRDENDNRLTLITEPEAAAMFCSKTGLLNLKVHDAVLIVDCGGGTVDLIAYEVEEESPFTVAECTAGSGDSCGSTALNRNFSNILRAKIRKMKLPDGSKTAGKVYAKCIMDFENRIKADFRNNGQKWAVDVGIEAEFPEAGIEEGYMTFTNEEILQCFEPVVNRILELVRNQIIAIQAQNRSLQNVLVVGGFGASEYLFQQIKLHVPPQFQNKVVRPMDSVAAIVKGAVTAGITERVITSRVARRHYLMATLQPFKEGHHPEQYRVPSLDGKDRCKYTRQIFVQKGQRVKIGEPVKVSFFRQVAPGATLMYEDVLYACDEDVCPEYTKDPRIKEIVTLTSDLSRKNLEKDFERMDTPQGTFYRVYFDIYLTLDGSEFNAELVCQGEVMGRCSARFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5T6</accession>
    <name>A0A9Q8P5T6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758617.1">
        <property type="nucleotide sequence ID" value="XM_047902380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5T6"/>
    <dbReference type="GeneID" id="71983110"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03232"/>
    <dbReference type="OMA" id="RWQGTLF"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF4">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="62217" checksum="20F7321D16DD6BAC" modified="2023-09-13" version="1">MASSSSSSPTAGAPVDTAAKTTHISTGSRNLTDFDRIEDGECHDDDYHGHLKTERKPSRQEDKDFTQFDRKDMKRMGKKQELRRNFRPLSTIAFTVILQGTWEVLLAASYQGMYSGGLAGLLWSYVWTFSGFSLVVVSLAEMASMAPTSGGQYHWVSEFAPPKYQKLLSYFTGWMSTLSWQAGTASGPFLVGTLIQSMATINNPGYSGTNWQGTLCVWAITLIVLVANVYGGNMMPVFQNLMLILHVFGFLTIIVCLWVLAPRNSGQVVFTQFYNGGNWSSIGLALMVGQISAVYACICSDAAAHMSEEIKDAGVTVPRAMIGSYLMNGGLGVVFLISFLFSVVDLDGALNDETGYPFLYVFRNAFSLPAVNALSSIVIVLIFAGTLSYNLSTSRQTWSFARDEGLPFSKWIAHVDPKLEVPANAVIVTCIVTFLLSLINFGSDVAFNAIISLNLVSLMITYMVSIACVLYRRVYQPELLPKARWSLGRWGVAINTGGLAYSTFAFFWCFWPNVYQPSLVDFNWSVLMFVVVAVIAAVDWVVRARKVYKGPVVLVEGWRDGRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6A2</accession>
    <name>A0A9Q8P6A2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758978.1">
        <property type="nucleotide sequence ID" value="XM_047901631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6A2"/>
    <dbReference type="GeneID" id="71982361"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02483"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="169" mass="18667" checksum="543816ABB04BD066" modified="2023-09-13" version="1">MAHQQALTSISQHISNLETILTGAAALALAIQPHAAPPHTTSATPSRKKPRAPSILQTMKSNLAARKALEASQRASLSALIETSIEQTESLLEWPKPPKNGQPSVFDTAFRALFELKEEQRRRIEEYERRARVLKMKLEIAKIAVKALGREVRGLREVVEGDVDVVMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6P1</accession>
    <name>A0A9Q8P6P1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator-type transporter ecdC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759604.1">
        <property type="nucleotide sequence ID" value="XM_047907374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6P1"/>
    <dbReference type="GeneID" id="71988104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08226"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="491" mass="53952" checksum="5B63C39444DBE7CC" modified="2023-09-13" version="1">MGHIEMEKNDALHVESESVSSGTSNQEMAAKNRVDLSAKEQYRKLWTAIKVDRLFGWGYDAGLSGVAIAFPEFREVYGNYYAKGEPWVIPALWQSLWNAASTIGQPLLWTAVTLSLASSFALVFAPNLPVLFVSKLLLGLSVGLSTATPPLYVTENAPAHLRSTASSLTNVIIVLGFFCSSLTGYGASKIQGVWSFKLAFVMTFLVPALYMLGLPLLPESPVWYMKKGREADARKAALKLYGANANVDSITDTIKQELHKEDAEAAGVSQTSWWAIFTKEHRARTFTAVLGLQSQNFSGGYFANTYQTYYFELIGQADSFQLTAISSTLQLFSNFVAVCLADVIPRRKGLIGGGTLLMFWSVIIAGCSVAPESNGAAVTALLAFMITWSMLYTATQLTALMLSSVFPYFINPDRLNWGGKIMFLFVGAELFIIAGLYWIQPETQNRTNVDIDAMYAAKIPARKFSQFEVVDGEVRPRAGQTGFVSRFSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P764</accession>
    <name>A0A9Q8P764_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759938.1">
        <property type="nucleotide sequence ID" value="XM_047907745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P764"/>
    <dbReference type="GeneID" id="71988475"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08597"/>
    <dbReference type="OrthoDB" id="10267104at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040141494" evidence="1">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="211" mass="21846" checksum="9BA73D4F90A631AC" modified="2023-09-13" version="1">MHTINWTVALVPLNLTEVLSAPQVSIGIPGLDGDGTLLTNTTLPTTLAATTTPTSDPSPTIITADPSNCDSDPEACDEAINNDPNRPPICFADDPTQADSVCIPYCQKILGSDPLVQQWGLTSTCIGAPGNLACFAVDEAIAWSEDLLKDIGKVSGMTASKWASAVLTVGSNVVAHGSKIGDSANPACPDHVFTVVDPNDMEAELGALNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7A7</accession>
    <name>A0A9Q8P7A7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760177.1">
        <property type="nucleotide sequence ID" value="XM_047903381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7A7"/>
    <dbReference type="GeneID" id="71984111"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04233"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="67" mass="7438" checksum="3C86074F5F6E7083" modified="2023-09-13" version="1">MDTSTAAQLGVLGFAAIMILAWLASKAAEVSYEAEQLVREPLLTRYDTEDDPDDHDTKVMRRDGHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7D0</accession>
    <name>A0A9Q8P7D0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047904276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7D0"/>
    <dbReference type="GeneID" id="71985006"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05128"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF79">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="392" mass="45555" checksum="39E961468F3808AA" modified="2023-09-13" version="1">MGSIAADSEEIVPFQVDIPQEEVDRLQRKLKDTRLPPKEIVPDASKKYGPTYEWGAHLYDRWVNEFDWYEHQDRINSAPHFLTRIDGIKTHFVHAKAKRSDAIPLIMIHGWPGSFYEFNQVWNELANPKDDSQPAFHVVVPSLFGYGFSDWPPRAGWTLQDSAHVYDKLMKKLGYRQYYFHGGDWAHWIGREMGSKLTDSCKLVHFNFAPSPLPDGVEYTQREQEVQHRVDDWLENHMGYAITMRTRPHTIGFSFNDNLMGILMWVGEKYNEAAGPENQKKRYWDHHILATASIYYFTDTIMPSMLCYYENVRHGEFASFAMKPDNRITVPFGYTSFYWDTAPSSKRAVERTGNLVFYKERNDGGHYAAAEDPQGIIEDIRALAAEHWPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7R0</accession>
    <name>A0A9Q8P7R0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcriptional regulatory protein RXT2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_04876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760654.1">
        <property type="nucleotide sequence ID" value="XM_047904024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7R0"/>
    <dbReference type="GeneID" id="71984754"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04876"/>
    <dbReference type="OMA" id="EDVFEWC"/>
    <dbReference type="OrthoDB" id="441210at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039602">
        <property type="entry name" value="Rxt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013904">
        <property type="entry name" value="RXT2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08595">
        <property type="entry name" value="RXT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcriptional regulatory protein RXT2 N-terminal" evidence="2">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="517" mass="56969" checksum="12D6263E16351949" modified="2023-09-13" version="1">MASQHSQFAETIRAMKLAMKRRADGSEGEDYIQTHTNRGNKLKRDARNVQQDQLDDTGGTSYKKNVNHAGYLRTTISTNPPLYDEDGDIYSPVSSDNEHRFAEPIEDNPFGHVRLESLLRPLTAASELPDHPSLSIPYKSKALTQMADEAFEMLRRERASLWKAKRLLQRFRGDADWVPCTTFETENDEMLLDGGEGTGDLSAVPSMFMDNAAFELGPPREVLDGPEAAGDDLIKHSRPDAMDPMVDGESMEGIEAVDMAAFAANASMSRVIDNTGIVEHGNSLEQESTAATNGDSGNGIEDTETNGHSHIRMDDATGTIPEQASNPTVADLAEREGASETASNSNGTNTHAMTTRARARSPAERSDRTPSPSPSDSASIPPIHSWFVAPAASLTDRDLGLPPNEAEDTRKLLLLYVQKQEQIVRSLDSLHAGLSKADRLRNYVYRSCKADGHLVPDGKGNMVTEMSDGEDWYDVSELNMQPWELKDGQLEKGKDEVEDVEEEGRRRPGRGRRVNRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8A7</accession>
    <name>A0A9Q8P8A7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Core trichothecene cluster (CTC) protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761299.1">
        <property type="nucleotide sequence ID" value="XM_047904338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8A7"/>
    <dbReference type="GeneID" id="71985068"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05190"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZN622/Rei1/Reh1 zinc finger C2H2-type" evidence="2">
        <location>
            <begin position="96"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="36611" checksum="AF582852C2429230" modified="2023-09-13" version="1">MVGTTVLCSTCNAHFNDNAIRRQHMGGDWHVYNMKRRIVELSPFSLEQYHSLVSEDHIKHEALETPETQLESAADNNLATPEYRGVDETETTNAAQCLFCLIMSNCLHDNLEHMATTHGFHIPRPDKLETDVETLLAYLQLVITQFTACLYCGHEKQSAEATRAHMLGKGHCMIDLSPESDFREFWEPIEGDTSTQQMLSETEMRTAAGTIVTSRQHQQSGLFERARSRTSQDVAIVQSTSQTAAQGERPEQSTSTSTSRSLALRDQMGIGGLSDTQRRGLAVVQNKMMAREQRSRNEARWVLEKFGNKTKQKHFKPDVPGRKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8F9</accession>
    <name>A0A9Q8P8F9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_06341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761556.1">
        <property type="nucleotide sequence ID" value="XM_047905489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8F9"/>
    <dbReference type="GeneID" id="71986219"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06341"/>
    <dbReference type="OMA" id="LVGWWST"/>
    <dbReference type="OrthoDB" id="1378at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08063">
        <property type="entry name" value="MPN_CSN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033859">
        <property type="entry name" value="MPN_CSN6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="17"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO17190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="42722" checksum="5BA39B81C79BD1B5" modified="2023-09-13" version="1">MANPLVISGRPDASNNIQLHPLVLLTISDYITRHTIRTQRGPAIGAVIGQQNGRNFTLEHAFECKLADEADDSDAVLDATWFTDRLDMYKEVHKVPALDLVALFMLGPVAGPQQSHLPVLKEVRDLTGSDNTMLLLFHPELVDDLQGSKLPISLYESVEENDAMRFKELAFEVESGDAEMIGVNFVAVGGGNATAVPKADAAGSAGSSSKDKKTKGKGRAKDGEEADANGAPANILSPEDDELITTLNSKVNAIKMLNERIKLLGSYLETLPASYLTDENLDAAPPADTNFTLLRSINAMLSRLPLLAPPPAAVSEADADGNVLAPASNLEKSAEVEKQDVHLTSLLASLTRSVAEAQSLGSKFNVVVRDKQQKERGGFGGRGGRMGGFGDDGLVADDRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8Y0</accession>
    <name>A0A9Q8P8Y0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05866</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762050.1">
        <property type="nucleotide sequence ID" value="XM_047905014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8Y0"/>
    <dbReference type="GeneID" id="71985744"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05866"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF15">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040387410" evidence="8">
        <location>
            <begin position="19"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="88"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="424" mass="45532" checksum="A6F59CD489F1C93C" modified="2023-09-13" version="1">MAPRNILLALAAAPGALAYPWVQNVAGVDSSLLERGYSIEERDSAQCPFNANHVNAPLVTAQHPYNNAKNGQPGNGKGGYLVPAPGDTVHEFRAPNPQTDIRGPCPGINVMANHGFLARDGITTYNELVDAQQNVYNVGYDLANLLAIAGVGLDGDLVGTTRLSIGCDATSRTATPGNILADELGLNGHNHFEADTSLTRNDYFLANGDNYRFNTTLFTQMMQYCQGNCNLEHLALYREARFNASKTDNGNFFFGPGSLLLYGAASFLYELMPTAGGIADEATMMSFFGADKVNGQYVKNSGERLPPNWRPRNDPYDNNKVGGQIIAMYLLHPVPFGGNVGPNNYLGLNFSSYITNGQLNQQTANYAMCLIYQTLTGAFPSELGQLVNLPVEVLGDIQQKLLGFGKNFGCPLNPNSGGSVDGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P902</accession>
    <name>A0A9Q8P902_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06186</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762004.1">
        <property type="nucleotide sequence ID" value="XM_047905334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P902"/>
    <dbReference type="GeneID" id="71986064"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06186"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Beta-galactosidase" evidence="9">
        <location>
            <begin position="350"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="682" mass="75331" checksum="FC15D384A15A6DDA" modified="2023-09-13" version="1">MHDDGNAVIVKLPLRRVFIFSGEFHYERLPVPELWRDVLEKYKANGLNAVSVYFFWSYHSARQGEFDFTSPGKVLERSWKGPGKDIQRLLDIAKEVGLYVIARPGPYCNAETDGGALAVWGSDGSLGSIRTSDETYHQAWLPWMNAVNEILSKNQIDDGGPIILYQIENELQETRHEANDTLILYMEQIEEATREAGIIVPFTSNGKGMRSQSWSTDYQDVGGAVDIDGLDSYPGGLSCTNINSGFNLPESMPEFEAGRFSAWAGDFYDQCLAEHDPAFADIDYKNNIGQRVTLQNLYMANNITSHLGNLAAPVVYTSYDYSAPLRETREVQLKFKQTKLIGLFTRVSQDLRKTIMVSNGTKNAASSADVFSWVLRHPENQAGFYTFQHNTSSSRAVTTFEAYLDTSLGSVTVPNLQLNGRQSKIVTTDYHFANHTLLYSSADILAWGTFGGSEVLVMYADVGQTSEFAWKTSGGNATFRTYGTAKLSPQRRTTATNSSTLTSYAYTQTAGSTVVVFDNGVTVYLLDTETAKNFFAPPLSSDPIVSPEQQVFVLGPYNVRSASLDGGTINLTGDNANATALEVFVGTEAASVTWNGKPVDTERTAYGALRATLPGAEDRTISLPELSWRTADSLPELRRDYDDSRWTVCNHTTTKCPVAPLTLPVLFSSDYGYYAGIKIYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9D0</accession>
    <name>A0A9Q8P9D0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762531.1">
        <property type="nucleotide sequence ID" value="XM_047904628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9D0"/>
    <dbReference type="GeneID" id="71985358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05480"/>
    <dbReference type="OrthoDB" id="276721at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="31475" checksum="4D0F2BE3EE0CCF8B" modified="2023-09-13" version="1">MAAPGAAAAAKKKLIVCGGNGFLGSRICKAAVARDWDVVSISRSGEPNWPSVSSHQTAPPWSKSVTWRSANILHPETYKADLEGANAVVHSMGILLEADYKGVLTGKESPISGLRRAFSATKQGGSTNPMDRQPGQQIEPGEKDGQLTYELMNRDSAIALAKEANNAGVQSFAYISAAAGAPVLPGRYISTKREAESTIASAFPKMRNLFIRPGFLYDSSRTFTMPMAAVTYGGFMANSLTGGNLTWLMGAGGAKPLKADLVAEAVVEGLSDDAVKGPVEVKEIEELANRAWRRGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9D3</accession>
    <name>A0A9Q8P9D3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762409.1">
        <property type="nucleotide sequence ID" value="XM_047905079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9D3"/>
    <dbReference type="GeneID" id="71985809"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05931"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="165" mass="19333" checksum="AB092E18AFC14DF0" modified="2023-09-13" version="1">MKHQMNAQKRKHHNESGELWWHSRANKAKHHFSIHADIIDLANMITEEFSLVGESMRVKELGKRIKTRTGEVYISTDHLPKSRQDDWKQSELRRRIHRRWKSSLVGSGISQARNIMSRKQIRQKVDADPAWPEALEPDDQQFTALPTQPKYVTRLTAESGTIDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB08</accession>
    <name>A0A9Q8PB08_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763519.1">
        <property type="nucleotide sequence ID" value="XM_047905945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB08"/>
    <dbReference type="GeneID" id="71986675"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06797"/>
    <dbReference type="OrthoDB" id="3690922at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="18225" checksum="B54CDED9D3FEE2EE" modified="2023-09-13" version="1">MYLQWLYTGEIVVTEEEWPPEEAEIAIHKAYVRPFYRALVYLYILADMLMDMTLRNCTLDALRSYIYHSPVVPNNVLVTKVFKDTPPGSKLSTLLVDIFACYTNCSFSANPKHDYPTSFYRMLLDRVVPAAKGTSVLQNPYTAPKCTYHEHDASCPPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB45</accession>
    <name>A0A9Q8PB45_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07438</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763610.1">
        <property type="nucleotide sequence ID" value="XM_047906586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB45"/>
    <dbReference type="GeneID" id="71987316"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07438"/>
    <dbReference type="OMA" id="NEICWDK"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="27"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO19244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10855" checksum="C114ABE410CCBCDA" modified="2023-09-13" version="1">MDQLNISPETAQGLQNLSAQDKQQLNQFVINESQKAQIQQTIHSLTDVCFRKCITSKISAGTLDRSEEPCMRNCVDRFMDANMTVIRHLEQMRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBR6</accession>
    <name>A0A9Q8PBR6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763929.1">
        <property type="nucleotide sequence ID" value="XM_047909066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBR6"/>
    <dbReference type="GeneID" id="71989796"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09918"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="32874" checksum="2C3A810A37067C9F" modified="2023-09-13" version="1">MENMMHRLDLTPGTPKDVLQNSTPKLTTKATFLSLPAELRNKVYELYFDGIDDRIRSSWIRSDDGSFCFSMRDFEIFLASRQVNAESASWFWHKHQHYFRGAKFVWSTSIRSIAAAWNRHSRAFAEEPEIMYNLDADSWYGYHGPRHTAKVNDLMDLLERSRASYDEAGERLVAFTGRHDVVESMRLPVQESEVDCEGDDGSVGRGFGPWCRQLRVQCNLEPYKVRFLEFYASDGAKAYKFRLRFCLKNQAVWLSGPLSRLDWALMAEDAVQGRRRRRFIGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD39</accession>
    <name>A0A9Q8PD39_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Indole-3-pyruvate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764591.1">
        <property type="nucleotide sequence ID" value="XM_047909851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD39"/>
    <dbReference type="GeneID" id="71990581"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10703"/>
    <dbReference type="OMA" id="FTHMAYL"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF24">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="595" mass="66521" checksum="44A91B7818F6D5EA" modified="2023-09-13" version="1">MAAVILPKSPHDITLPHFGGASPTVSPQKVEQPYEIAQKWLTSFEQVLANQDAIKLGPLLHEDSWWRDHLALSWDLRTIRGSSQILDFVSPLLENAGLHNFHLQENGKFAPHKDQPIPELEWIEFMFSFDTSVGHGKGMVRLATSPSNVWKAHMIHTSLQALRDFPELKGDLRPHGGTNSLKGGVAEGNWYERRQRQKKFLDDEPEVLIVGAGQSGLNLGARLQALGLSVLILDKNERVGDNWRHRYRTLVTHDPVQYTPMAYMKFPENWPLFTPKDKLADWFELYASAMELNIWLRSTVRSAEYNEGSQSWSADVLRADGSHRSMKPKHIVMCTGHAGEAYIPKFPGHELFEGAVYHGSQHKDATFQDNIAGKKVVVLQRKGTYVISAKQGLFMLHEGMYDEHSPPTKDADVAGQSLPIPVQFALNIGLTESIKTVEKSNIDGLTKAGFKLDFGHDGSGIYRKYIEIGGGYYIDVGCSQLIIDGKVKVEQSPEGIKGFSERALVLADGRELEADVVVLATGYDNMRTTVRKILGDRIADRCKDVWNLDAEGEVNAMWRPSGHPKLWFMGGSLALCRIYSRHLALQIKASIEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDI9</accession>
    <name>A0A9Q8PDI9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_09983</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764859.1">
        <property type="nucleotide sequence ID" value="XM_047909131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDI9"/>
    <dbReference type="GeneID" id="71989861"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09983"/>
    <dbReference type="OMA" id="STMPKFE"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="189"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="392"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="541"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="541"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO20493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="583" mass="62279" checksum="A983BBE8D72C43EB" modified="2023-09-13" version="1">MSYGGGGYGGRGGGGGGGGYGGGGGYGGSNGYDSNYGGYDYGSRGGYDDRSYSNGYSNGGSNGYGGGGGGYSNGGGYGGGGGGYGGGGGGYGGGGDKMSQLGAGLKQQNWDMDTLPKFEKSFYKEAPTVAARTPAEVDEFRRVNQITIQGRDVPKPVETFDEAGFPNYVMSEVKAQGFPKPTAIQSQGWPMALSGRDVVGVAETGSGKTLTYTLPAIVHINAQPLLAQGDGPIVLILAPTRELAVQIQEEVSKFGKSSRIRNTCVYGGVPKGGQIRDLARGVEVCIATPGRLIDMLESGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIIGQIRPDRQTCMWSATWPKEVRQLASDYQNNFIQVNIGSHDLAANHRITQIVEVVSDFEKRDKMIKHLEKIMEDKANKILIFTGTKRIADDITRFLRQDGWPALSIHGDKQQNERDWVLNEFKTGKSPIMVATDVASRGIDVKDITHVFNYDYPNNSEDYVHRIGRTGRAGRLGTAITLFTTDNSKQARELVGILSEAKQNVDPRLAEMARYGGGGGGGGRGWGGGRGRGGGRGGRGGWTGSNNAPLGGERQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDJ6</accession>
    <name>A0A9Q8PDJ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764831.1">
        <property type="nucleotide sequence ID" value="XM_047909068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDJ6"/>
    <dbReference type="GeneID" id="71989798"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09920"/>
    <dbReference type="OrthoDB" id="3647344at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="167" mass="18808" checksum="AF7F4E6933F43951" modified="2023-09-13" version="1">MASARAHHAHVDGEIMDIYDVHFPSMKDMPLPEYLQAITKAMLEAPNRIPPEANEEILGRHCSTDFKVTAGRPETNLIASNLEQHTRNLKAFIAANPDYHIEVQNTTIQLDDRTGRAVIFCTTRVSGLFGAHGVRQSVNQVRARRRQDEHWVAYELASLRGPGHLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDL2</accession>
    <name>A0A9Q8PDL2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 14">Cutinase</fullName>
            <ecNumber evidence="3 14">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_10174</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 14">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 14"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764857.1">
        <property type="nucleotide sequence ID" value="XM_047909322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDL2"/>
    <dbReference type="GeneID" id="71990052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10174"/>
    <dbReference type="OMA" id="FFGFTRN"/>
    <dbReference type="OrthoDB" id="3225429at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000235">
        <property type="entry name" value="Cutinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Samaras A."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">Race5_Kim</strain>
        </source>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="652"/>
            <end position="678"/>
        </location>
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        </location>
    </feature>
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        <location>
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            <end position="787"/>
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        <location>
            <begin position="21"/>
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        </location>
    </feature>
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        <location>
            <begin position="48"/>
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        </location>
    </feature>
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        <location>
            <begin position="77"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
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            <end position="721"/>
        </location>
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        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
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        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21509.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="810" mass="86168" checksum="14305FF1E80E2061" modified="2023-09-13" version="1">MGTSARKSFFQEVDVDDLEPETSLSRSSSTASESSSSRKRPSPGVRFRTKDDVRLVERYEDADVGGNNHELSAKPIPSTNAPTQSPLPGSKSIMYRLGAKALLVVAAVPFLHGAPSFGHASLPLQPVSGGPIRRNPDGPVLDKRADSPTDVCFRWAGQSAVVNGTLYYYGGQATSEPNQDTNTWNNNFLSLDLTKTWQISTPSLTGLPQPSGPPNISLGTLWNSHDSLFLYGGQFQWKPPVSPTAYSTWEYNIASSSWVEHSDPVTSEGVSSPSNDDPVQRAAEGAAVNVASLGRGFYFGGHLDGYTTEEWSQSIARVYLQSLLEFTFPGYQNDQVNALSDNKDAGSDGVYRNVTQGGLQSQAGFTQRADGLLVYVPGFGEQGILLALAGGTNESFTQMNQINVYDIANSTWYNQATSGEYPETRVNPCSVIAAAPDGSSYNIYMFGGQNLIPAGNQTQYNDMWILTLPSFTWIKVDQSGQSVPPGRSGHTCNIWDGQMVMVGGYTGANSLTCESPGIYVYDLSTTSWVNQFTATSAESDSGSTSGRAQADTNGDAEDNPFNQQSAQRYTSDNPGGLEGSYGYLVPQAVIDVVGGDKTGGATLTTPVNTATSGPLATGKPLTYTVTNADGSISTSTSRPGSGSGSSGNGVNVGAIVAGCVAGFFFIVACYLAFCAYVYRKQLQLYKRHVEMSQAQARGEKLPAIPGLLATDASTGKITPSDPSYRRGDGVSPWLTNTSSGSMHSRDDSGGASGSYHRNGGNGVVGGGYNSVRRSSETSETNDEDLLNGREPTFVGVMLNPRRSLRVINRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFA5</accession>
    <name>A0A9Q8PFA5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_09398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765784.1">
        <property type="nucleotide sequence ID" value="XM_047908546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFA5"/>
    <dbReference type="GeneID" id="71989276"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09398"/>
    <dbReference type="OMA" id="IRDRRMQ"/>
    <dbReference type="OrthoDB" id="189459at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046834">
        <property type="entry name" value="ABC_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019195">
        <property type="entry name" value="ABC_ATPase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046833">
        <property type="entry name" value="ABC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049069">
        <property type="entry name" value="MRB1590-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38149">
        <property type="entry name" value="ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38149:SF1">
        <property type="entry name" value="ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09818">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20446">
        <property type="entry name" value="ABC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21117">
        <property type="entry name" value="MRB1590_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase of the ABC class N-terminal" evidence="3">
        <location>
            <begin position="61"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase of the ABC class C-terminal" evidence="2">
        <location>
            <begin position="236"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="MRB1590-like C-terminal" evidence="4">
        <location>
            <begin position="553"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO21418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="642" mass="68642" checksum="0E1558207CF3EF4F" modified="2023-09-13" version="1">MSAGRGRGAYYKERYGGGRGRGRGGSQRGGNDGSHFQQQQSSGNEYLEQPRAGGPPKDWAQLDADLRSIDQQQYGSYKRLVGKYQHVEPQFTLSVDHVQGDAYAAPSRVRAIMPWKETRLPDHVLQSDVSRIALCDFVSRIAGALIQSKHLDQSIAKTGGGWSGPKGGAFSINAPGQEIIPRTSALISGNDSIELRFTVSLPAAGRTVLGQQAYQILAINLVEVVKQSLLHANIDHKRLGDHISSAEAQNSLRSQLEEHGLIAFVANGSILPRASGASQAPMSGPEVVAFKSPKELEISLTTSHGASYTGMGIPKGVTMLTGGGFHGKSTLLEALELGVYSHIPGDGREAIVTDPTAFKIRAEDGRSVNKTDVSPFISTLPGGKDTKSFSTSDASGSTSMAANIQEALEAGCKTLLIDEDSSATNLLVRDARMQKLIRHEPITPLVSKARALYQQHGVSTVIVIGGLGDWLAVADNVVSMDSYVPQCKTKEAQEVLQQLPSTIVQDKKYGSPPQRMFRVGLEGIRSPFASRNKFIAMNSHTKDAVDDPSRAESGIDLGALDQLVEIGQSRTAAVLLQRIANITSTSALTLREIKSQLRDCIGVDKCLPTSLDGGDLVGIRPLEVAAALSRLRGLALRVDRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFD8</accession>
    <name>A0A9Q8PFD8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765790.1">
        <property type="nucleotide sequence ID" value="XM_047908710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFD8"/>
    <dbReference type="GeneID" id="71989440"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09562"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="9824" checksum="5F58E4DB2BA67D89" modified="2023-09-13" version="1">MSDTSVIFDQPDRRDSDTHDTTYNADGDETMSLSPTPPVTNAPNDTIEQPGGSSLTAGPGIAPPIAVQAVSGRDSTSQQSQLQAPALGQGNTQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFP2</accession>
    <name>A0A9Q8PFP2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765981.1">
        <property type="nucleotide sequence ID" value="XM_047908914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFP2"/>
    <dbReference type="GeneID" id="71989644"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09766"/>
    <dbReference type="OMA" id="SENTWFL"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="25016" checksum="A0D53CAA2D4B76CE" modified="2023-09-13" version="1">MESPANLLTLPGELRNTIWRTVVQTDRLLDVEPLCAGSSTTKLHQPALPFTCKMLREEVLSIFYSENSFFLGKVGYHNYGDIRLYEFDLRIQRWCYKLGEQANFLTRLSMIIDGLCYAWDDGLMPGDAMYEMDTRNGSIRFEMNGRPRCLCRLRDAVEKSAVRDGRRLLDVMKEYSTCYCEAVKEGRCNQCGLSRLETFGQGRQTRQKNWDNIITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGH9</accession>
    <name>A0A9Q8PGH9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766414.1">
        <property type="nucleotide sequence ID" value="XM_047908200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGH9"/>
    <dbReference type="GeneID" id="71988930"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09052"/>
    <dbReference type="OMA" id="NEAEWAV"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04433">
        <property type="entry name" value="AFD_class_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="574"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1183" mass="130150" checksum="CA683CB5AFFF73D4" modified="2023-09-13" version="1">MGETMLSIEYGPKVGTQKESHLQLWQDVVNARPNATALIAKHQSPSTFRWVGSQHVDTPYVQWTFADLDRGARRLATALNRLTHIDRRPIAALINNQAEWALLYWASAYLHSPFVPINPKIATRTEELNHMLDLVGPAVLVSADLQIASQLEQSVSEKLMSSIDVRLTLSASGAETSQTWGLLGNVMSGEPTPPDTPDVMSADDTIVILFTSGTTSLPKPCALTSFQCLNAALGYMDAQKVNSSHRFVQHLPGFHSYGIGWSLGFWLRGGTVIFPSDSFEAQATLECFDQHGATHMGLVPTTAQAILAHPAFAKTDLSTLVSIDISGAGVLPSLVEACTAALKVPSSTSYGMTESPGTAAWGVDEGSVLRDGEVMSGRPVRNTVQKICEPDSRDAVPRGQLGELHNGGPQVILRYMDPRVSTKDFYQDEDGTRWIITGDQAVMDHDGAVRITGRYKDMIIRGGENISPAGIEDYLSKKEAVFQVYVVGAPDDMAGEVPIAVITTKEGQEADIAALKQDVTRDLGAAFAPKLILHLNKDLGLDAFPSTASGKIRKVELAKVVKEYLKAQAEAGLDKSGSTIDSLLGIWKMISGADGLLPSTTIDAFADSLMMMQLSGIVKKEFDRDITVEDFKLCESIQDQADLVDSRPLRSAVITKPRREGPPALLDMPHAREDVEVYERTQHAVADMLAPLGMKWDDVEDVVPLPDWDAIFCHRIRPSSWNLRFSYNAPVGVEALEKAIRASLEFHPTMRSMALDQDGETLLVTLRSTEEWCKASITTGWEVQTKEDLNTLVLNDPILDNASAPGPLVKFHVAKILEDGTSGLVLVASHAVNDMSMTKVWLEDIVNLLTGEATPVHHAQFKDYATAFFDHRDGLEADNGIELFARKHQGVSLVPETTFWPPQRAPEWFKGVDAGWSRWTGTKARKGERSVAQSEKVKAQAGIRRAVKVDDLQRLKAEYNVPVFMLVKAAIAILNISRTGGKEAIFGTINAARSWPFSSDYNALEREAYTGNPLDISGCTTEYVLDRISVGSSKSLLAFMQQVTKDEEQNSAYAHTPIFRIIDRLRDPISADDTRTFAERERDAASYLPLIRRQSFNWLPTAPTAQNPKGLRFQQMLTRMDNGLTITGFLMDDKRSVALGFSWDAEHLSFTEAERALNDLTGLVDKMGKEENWSKSVEELLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHJ0</accession>
    <name>A0A9Q8PHJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766954.1">
        <property type="nucleotide sequence ID" value="XM_047911167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHJ0"/>
    <dbReference type="GeneID" id="71991897"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12019"/>
    <dbReference type="OMA" id="ISGCYAR"/>
    <dbReference type="OrthoDB" id="166375at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.200:FF:000005">
        <property type="entry name" value="Related to Pol II transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115:SF8">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Plus3" evidence="7">
        <location>
            <begin position="262"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="556"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="513"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="617" mass="69198" checksum="D8E07AE05A4F00F7" modified="2023-09-13" version="1">MSDVENGPSLNEELLDLVAGDSESEADDIDRLDEVDVEGSRSPSQEPKPSVEKVEDSQGTRRGVAQKVKSRGRRKRKQESEEEDAGSPSPAESPRSGGMDESDGEADAPAEEDDEAPLFPIDGKFRDESDRVRVMAMTEIDREAELAERAEQIIRHRQDMTLKRATMQSQAAASRNKRKAAEDLEDGNKRSMRPKTAKQNALDSYRRAREEKNTQRSRMESDRGRRDDRDERSPSASDRDADGESEVEWAEPAYESRRDDPPADLRDFERCRVGRSNFAKVCFYPGFEESIRGCFARISIGLNQENGQNMYRMTQIRGFTEGKPYQLENAHGKQFTTDQYALVAHGAAEKAWPFSACSDGKFNEAEFTRFRDTLQKDNIKMPSRRFLTSKLDAIHDLLNQKFTEDSLQIKFAKQRAMELKFDPAHIARQKRKDIAKRRADAEQNGDEEEIARCDSELEALDNSAANTNGAVKAKPVMAKTTPQHDRLAQLNHTNRHKEQERVRQALIAERKKEIKAREAMKEKQAQAAKLKAEAATKSGKREAALQKSAMKDLFGEGSDISRAGTPASGIDTPKKSRAQTPLTQPANGTKLPVGALKKKNLDDDVIGGLDLDIDVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIS6</accession>
    <name>A0A9Q8PIS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_12121</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767531.1">
        <property type="nucleotide sequence ID" value="XM_047911269.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991999"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12121"/>
    <dbReference type="OMA" id="AVWKRAP"/>
    <dbReference type="OrthoDB" id="18982at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="104"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="304"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="388"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="451"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="591"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="953"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1731"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2045"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1731"/>
            <end position="1747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO23165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2184" mass="238653" checksum="C091D6192A4D5876" modified="2023-09-13" version="1">MSSWWQKKLLRYALRYVLQRTGLLEDHVIDLDQLDITVGKQSVIELKDVGLNVKQISKKAHLPPSLRLEVARVLSLRLTIPADIHQSSVVVEVDGIEVVARLEEEDVAHTPPQRTQRAQSPATTRTPQHRKTNRRIHSPPPYHPGALRESDDDVRAPTIQHVAKSFLMEEPMQERRQLEAQVAAESQNIEESFVSESSEGDTAGTGTGVGVPGFLSDLLQGIMDRFKLEIRNVEVKVKTDLRTYEETTVPITMRLAIGGAEVDDLAAPTGHVEKKASLKRSIQIRGISVALLSDKTVLSETSGLSSRASRQWSVPPSRAALSPTSSDHALKMAASRRTSSASARKPLLSTSILCDRAFRPTVASSSPTPEPLTSVHESLPQNLDTQDFAHADPEVPDEDTQAAVSASDIRAGDDNVSWGSRRSQSSAPAEDLWKSMVSDDDLPDSFIVDEHRVSTPKVSPSRTNSPLAGRQRRAVSPYDRSIHSPASWPRLEESPQRQRIRQGPGSWPAPDQSVHSTYDPLDQVLTDSRRDENVTDNKRVALELSEHDRGTIEPPPEPQEVIGDDMLESRFYSHEEAQSMYMSAMTGSPEMAMPGGWGSDVQSQRSSSPEVDRKLSPVDLPSLDEKTSRSQHIASGNVTPRAGSPNSPRRRTLGAGKHSVPEMVTELIYVDEMTIAVPVPGLGQTSVIDQPQQPAIPATRQNRNSPQGMPGTFSAYSEMSSSMRRGASSVYGEVNSVLFTPPEGVTSTAENTSVDVAVGAVTVRADFATCKLMHSLSTTASFAIATDGRQDSTAYVKAEPATSMALSFTIQLSHLSVSLRESVDAAIPRDHLDTSTGILDVRCRDIDVASADDTSLRIGDLAVELGGADLLTLKREERDVQASHSTASNAAAISLTVLRNRIGVNGTPVTDVALQTTRARLTFDLEQVDAAFDSFGGLSGVLELGSSFLSESGPTSSAIPKAPKGVRFAGDTEPTGSTPEVKLNARIDGATLLLRAPSCSVELRTSSLKAIYREQGAVATLEHITVSGPCLEGDVQSPLALDLASLRIEYLLTPQDKDLERLLSLLTPSKDKYDTDDDILIDTLLRQRRKGSLLRLAVGDVKLKVDDWQSLQSLTALGDDLTKLSAVTKYLPEDDRPGLLILLRVKDAEAQLPVNDRFGKLRICLQDLHLAQVGLPALLAFSLGTVKAEQVEGVQLLHPLIQQTASDNLPVIMARMLGDEAEPTVKIKVLNLCFEYSVPVILDLTGMDQEMDTEDLVVAVAQSVANLAMTDKPATLERSPGSDVSKVATKKTNIDLLIHDSAIGLTPQKLSSKALVVLSDAHISTTVPPEATVAVKLDMRKASLLITDRHLEDQITPSGPDRVSANYTNTTAKLNVVLQRQGFVSVGSLMSAEISFCATGDGVSDAKSVEVDVKNELFLLETCADSTQTLIATLGALTPPTPPNKVPKYLTEPMPIEDLVNSFTGEALPQPEPVRAAETLFDVEEDLAEDDGLDMPYSNSNLYDEPDDLLTHSALTGSLYGPISGVFGADDVDERESTIGEDYPETAESLLEDDPFEMTNEADVRMGDAALLRDLGRQCKPALSNDVIDVGLYEIEDLGYDALGCGQQALGSQHRFNAPHVGKRGRRTQAHANKIPFRLRLRDFHVIWHLYDGYDWQRTRDGIVEAVEQVELKAEERKARRRQSHNDQEDDDSVIGDFLFNSIYIGVPSDLDAQDLRRQINRGIDEDVSETASIPVSGMSRPTTYSASGGPSRQRQRRRLKLGRSKNHKISFELKGVAADVLVFPPGSGEIVSSVDLRLKAFEIFDKVPTSTWRKFLTHMTNDPRAREMAKPMFHIQLDTVKTLESHSASEFMLHVTVLPIRLHVDQDALDFITRFFEFKDESMASIEPEGERPFIQRVEVDTVDMCLDYKPKKVDYAGIRSGKTSEFMNFITLEAANIRLKRAILYGLNGFEELHPQLNGLWMPDVTRNQLPGVLAGLAPVRSLANLGMGVRDVIAIPVREYQKDGRIVRSIQKGAFQFGKTTASELARLGAKVALGTQTMLSNAEDLLSPPTERSSRPGTGRRVSGEQAWHDVASDDEEPEQRAVSAYANQPLGLLQGLRSARRHLEHDLLTAKDALIAVQGEFLESRGPGDAAAAVVKHAPTVILRPVIGATRAVGTTLLGVGNQIDRNNLRRIDDKYKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIW8</accession>
    <name>A0A9Q8PIW8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767855.1">
        <property type="nucleotide sequence ID" value="XM_047912508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIW8"/>
    <dbReference type="GeneID" id="71993238"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13360"/>
    <dbReference type="OMA" id="PYMELKL"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="14159" checksum="AAF9580BE5593D58" modified="2023-09-13" version="1">MVLQSGTHTSTLDQNLNGESQKEIAFNFLSLNSGLRQRLWGGRPHVRLSLLCTRQDFQRQGAGTVLVQQGLALAEQLGLPGYVEASTVGYHLYSKLGFEQVDTATIKAADWDGDRDRTLVAMVRPATAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ37</accession>
    <name>A0A9Q8PJ37_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flap endonuclease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767722.1">
        <property type="nucleotide sequence ID" value="XM_047912456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ37"/>
    <dbReference type="GeneID" id="71993186"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13308"/>
    <dbReference type="OMA" id="CELYFAW"/>
    <dbReference type="OrthoDB" id="2959108at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="142"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="463"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="551" mass="60776" checksum="0910C5BFE926BBCD" modified="2023-09-13" version="1">MGIPGLWEEVERVLTLQDTTLAAESAACVEAKGRPLRIAVDASVVIYKLRESTRPAAKYGGMNHPSRTFMTTACNLMIQGVQPVYIFDGPGRPTCKRDKFRPIAKRTNLYVPPPAPNAHGTRDIEQEYEFTHVEDLAKQVLDLMGVPRWDAPGEAEAECVALEKAGLVDGIYTSDGDALAFGGQCIYRARKNDQEEEKNDKEEKKKNDEELQKIQAADLETAGRPAKVLALAALLAGGDYRHGLRNCGFLNALRIVEKSAALEKLYHIGKSTAKEEARKGMLNGWRISQRDTFVGAVRNISRLIADTVPSDWPSAQLLGLCLRPMISDDATLEQLRSTIWIPKQPNIVELRAFTARMFGWQSRQRAKQFLHRLTPGLLANKLMAAGCQGQDATDLIVQAKAKQQRKDTANRSPVVKVSFMALEIAPIDYDGEPIVPGFEWDERDKKDPKVPYEEEYPEFLATFGAPSSLPRNAAGRNSGNSKRPAESDTASSSTKKAKATRRKPSAESTNTQRNSPSTVGTTNNGFTISGFRMPTRLDISFAGNEDVIDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ38</accession>
    <name>A0A9Q8PJ38_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_12848</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767769.1">
        <property type="nucleotide sequence ID" value="XM_047911996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ38"/>
    <dbReference type="GeneID" id="71992726"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12848"/>
    <dbReference type="OrthoDB" id="2960936at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 11 14" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="111"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="38"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO23403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="442" mass="49353" checksum="A1F56215FF68CFD4" modified="2023-09-13" version="1">MNEFARFSKRAVDYIFDRPVRNEDSSPIWCLGRSYESGYEASRPPTASGTSPSSQSDASHADSAIVTQSSTLPASTKAEEQGEANDEELVKSFDQVQLSKSMDEEDLGWPSEFLEDVESRIWLTYRNNFPPIPKSSEAAATSAMSFTTKLRNFANKDGFTSDTGWGCMIRSGQSLLANAILVQRLGRNWRRGDHERQYKDILSLFADTPESPLSIHKFVEHGAQACGTYPGEWFGPNATARCIRALTEKYHEAGLQVYARPNDSDVYVDSLMQTATQKDADDNFQPTLIVLGIRLGIEKVTPAYHAALKAALELPQSVGIAGGRPSSSHYFIGHQGDNFFYLDPHYTRTMLSPQPSTEDIETCHTRRVRRLSIAEMDPSMLLGFLVRSKEEFEEWRKAVSEMPGKAIIHIHETEPKYATGNERAGAVDEVETLEESLDEDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKR2</accession>
    <name>A0A9Q8PKR2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Efflux pump azaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768639.1">
        <property type="nucleotide sequence ID" value="XM_047912568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKR2"/>
    <dbReference type="GeneID" id="71993298"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13420"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="52"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO24273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="468" mass="50201" checksum="CF5694EBE1879B89" modified="2023-09-13" version="1">MAFKANETTPLLADSIPKLASDEDSDDTVLGSDDGDGRLLHDATEQPFNHWQIFALCCAAVTEPVACFCIFPFVSEMIQATGGLEESDVGFWAGAIESLFSVVQMGLMIIYGRMSDRFGRKPVLVFSLAGLSISTALFGLSRSLWQMVMFRCLAGSFAGSVLTVRIMVAESCNKSTEGRAFAWFMFARNGGILLGPVIGGAFVDPRLTSGISLFEQYPYLLATGITGAVCLLGTLLVAMFCHETLAEGDKLAKTKIQSMTTWQLLKAPGVASGLYIFGHTMFLALANTAVLPVFLFTSTANGGLGFSPRWISYFLAGLAASQGLWTLMSFPTLKRKMGTRKVMQICSCGWPLLFASMPVLNEVLRRDAIAAFWAVVPVPLIIGGGVAMSFAGAQLLVNDTCPSPTELALLNALTQTLNSAVRAVTPALFTSVFALGAKTQLLDGHLCWVVLIALTVPLQWALFFRAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKS5</accession>
    <name>A0A9Q8PKS5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-oxoglutarate-dependent dioxygenase citB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13963</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768598.1">
        <property type="nucleotide sequence ID" value="XM_047913111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKS5"/>
    <dbReference type="GeneID" id="71993841"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13963"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="225"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="367" mass="40627" checksum="087189F1AC8F857B" modified="2023-09-13" version="1">MSISMPRKAQLPRTATLLFGAYRIQSHVQAGHTCSSFNSRAMSTQADLAIPTIDVSSFLKQPSSPAAREVIDQVRAACETTGFFQIVNHGIPSPLQESVFTAARKFFALPMEEKRSLDAKHNVGHRGYDVLESQSYEEGVLPDLKEGLYVGNDIPASDERTKSGRFFMGPNVWPQSLDSADLRQPVEAYYSAVYALSLRVLDMMAPALPYDVKDLFSRFTGADLVAAPLRLVHYPPARATKQRQLGSSAHTDFGAITLLLSDGVPGLEVQNRKSGSWMQVPPSEDAYVVHVGDMLQMWTGGRLKSSVHRVLNGEERDRYSIVFFFDGNLDCPLTPLDEKDRIEGQEVPTVEGHMLKRMADSYGKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL10</accession>
    <name>A0A9Q8PL10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768700.1">
        <property type="nucleotide sequence ID" value="XM_047913190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL10"/>
    <dbReference type="GeneID" id="71993920"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14042"/>
    <dbReference type="OMA" id="ATCCWSA"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="56085" checksum="B97AB39753AA1E4A" modified="2023-09-13" version="1">MANITQYLSNPQFLTNIQNVDAGGCPAPFISESLYPFREGFYGGRNCAPNPLVTTPGPARCCIPCPVFHWAYLPDFDGLVDGAAWVNVAGFILCFILLLSMAVLPERYIRRSYLTMAMLVSIMILELGFIVPLARKPPQCYDPVTPNGMHSNGTCAFGGAAIAFGLMGYTGWVLVRSLFMHLQIVWNITPADISYWAANVVVWSITIALTAAVLAHVGVSFRFGGYCHVNVGSYSTYWGWILAFGGIALLLQLGTFIYCMKVYVSYALAMRNDPSQRSASVTGSSRSRTARATARRVRQVLLLQWRSLALVSLAIFTTAFVCIVFIVFDNRLTVQAFANTEELIPWLLCIIATQDASQCTHLTAPVIISESLALATIYLLSLIGPTAFFLLFRLDILKGWWAFIRTPFWKKRRGSEDSGGSKDRWVGGSKSGTQMSTSQRRKSEQDHDVEVGPTEVESPRDAGGLMRQPPREQERPVSSILEGRKGPKGERPVSGGSVTFDDEKGVGRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLJ4</accession>
    <name>A0A9Q8PLJ4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768970.1">
        <property type="nucleotide sequence ID" value="XM_047912559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLJ4"/>
    <dbReference type="GeneID" id="71993289"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13411"/>
    <dbReference type="OrthoDB" id="3921930at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="12"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="46136" checksum="86F8D0B58C46FF19" modified="2023-09-13" version="1">MQQRPITEEPCYAAVSYRWGMNNDGDSRLTRSVEVNDRPFYVTQNLFEGLRRLREQSEIRILCIDAVCIDQSNSEEQSQQVASMARIFQQASEVLLWLGEGETESMDRATFDMFMRIGQAEARTKTSADGDAAIPLTFLLSALLHDGQDLCPDEQSLSCSICHALTSFAIPSTPETTSGEEWFVEACAAVFDKTPRLLSLAMRKGHILHQLASRRYWSRRWTAQELNSNQRRKMYWGPCSIDASGTQGDNIVRLVKCVNLALELMLLRTDPAQQERTKWLREAWLSYKGLYERLRDVHRIGRLGEDILTAPPRDTHDLLHALSACAGMNCSDPRDRLYSLLSFDRGAKITPDYSAKTTEVYIRFARHLIDTGHSGTLLRNMLRNSNPSGGHIELPSSVLDLRSPLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLY4</accession>
    <name>A0A9Q8PLY4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
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    <sequence length="420" mass="47792" checksum="868F232F2A71403A" modified="2023-09-13" version="1">MAHHNGTMPDLGKPQSEARAWFEPVLVVSIMAASLYFNRDRTFSLIPSRNERHDPSDEHLIKNPNGEYQESRSSSRSTSPDRPKNSVDVQRGTSPSQWEDPVSPSTLNIPSRILQKFPFLIEMFYWALNYVAYSMTKKIGAAMYSRYDGQNQVTELAQRHGIDILTIEHDTIFTIFFPITEVAFQQFFLKHHLLILSFFNQIYSLVHIPGTVAFLSWYYYVAPSHDTFAIVRRTMTLGNFSAFFIFSFYPCMPPRLLPESFGFKDTVRQDNAESVWVGGANVNQLAAMPSLHFTYAFVVGCTFLYQSGILATCFGRRASVAASRTSRSWRSIMSVVYAVAGVIYPILVLSVIVATANHYYLDAVVATFSVTLCFFINRIWNVLLPAERLLCKVLRLRKPTPTTARNSIPDRPRVVVEQWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMX1</accession>
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            <dbReference type="EMBL" id="UJO18627.1"/>
        </source>
    </evidence>
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    </evidence>
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</entry>
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</entry>
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            <authorList>
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            </authorList>
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</entry>
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                <person name="Stergiopoulos I."/>
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            </authorList>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21221.1"/>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT20</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        <lineage>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="209" mass="23692" checksum="D982589AFC477060" modified="2023-09-13" version="1">MTNLNIHMQPNWLPLTALPRFCFSSAKQLPTKQPEPPQQPSKSFADLPAELRNQIYNYTLVRSAPIELPYAYEKAYFREPALLAANSWVRAEALPIFYGCNIFETPSPPSAHRFLKQLAPENIARIRLFRPIDLILPLSVHRRWSDALRGNLNRLVADSGKGALSSDAVHVPIRNDAGEASWCKLDAIEDFKIVPGSEGRWSIEWRETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT37</accession>
    <name>A0A9Q8UT37_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT37"/>
    <dbReference type="GeneID" id="71989221"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09343"/>
    <dbReference type="OMA" id="PFVERMF"/>
    <dbReference type="OrthoDB" id="3883941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="32831" checksum="EEE6DB3D578E4C89" modified="2023-09-13" version="1">MAAAASVPDAIAPTQKKRPRLNPARRKTAKAKVQSEATPAVSVAKTRGESALEVKKSSPTASIKPKPSTRQNSIPTACSSSHSVVKPTRAAPKSSQKCQNSAKQDLPPPPGAGGGSNASTVALAAPSFVTGGLLGCAAGAAVLLGSGLLKNAVGVDSAVLAARSAKAVLNNLIDDSITSMKAGTYSSADSLDMLRRTTLAYATLVPGGAPFVERMFREVEMIRRQRGHEVDKVVADASAELSVAGKKGAGPAELQSIIVSNLVKISQFAGTATQDIVARNPRLSPFRDGAAKALRPPPQPKTPTLKLNMTMKQKQTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTK5</accession>
    <name>A0A9Q8UTK5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Indole-3-pyruvate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766248.1">
        <property type="nucleotide sequence ID" value="XM_047908315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTK5"/>
    <dbReference type="GeneID" id="71989045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09167"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="789"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="809" mass="89821" checksum="9C8268828F49BB17" modified="2023-09-13" version="1">MSCSPDMFPHPVKTYRSTPYDRIAPRNATFDGAGKTVVITGGATGVGLSVANSFAEAETSRIVIISRSATSQQKARVELQNRHPKTKVELFQGSIDNIYRIKEILNQVGTPDVLVLSAATSHKHVPTIQIPDDEMEENWNINVLAQYKIVMAHLAMPKPAGAQKTIVNVSSACGQLIVPGLTGYGPSKAAFTQMVSHLAAEYTPEKDGVRMLNFHPVRDKNADADKIATIVVDTLDTCLAKEDYEGVSRLVLKDGHWRDHLASSLDFRTVKGASNVIFFLQDNSAVEEIIIERDTDFRKPHFGPLNLNGDPENITFHVSFRASHGTGRGVFRLLDEGTGWVISTVFLSLQELGGDQEPEGTKRPDGPFDDEEKKIRNWQDRRTEANEFKERDPAALVVGAGQAGLMASARLKMLGVDTLAIDTNDRVGENWRRRYHSLVLHDPVYFDQMPYMPFPKSWPLYTPKDKLADWSEAYASTLELNIWTKTKLVSSQWDKGESKWTVELERTQSDGKTEKRTIRPWHIVQCTGHSGKKLVPEIKGMDSFKGDVLCHSSDYTGVSQEGHDIYRDYYEHGYAVKMVQRSSTCVVTSSSITNVGLADADLWLWGMPPELFKAQQSKVSGLQKDTDSEILKGLEKAGFKCDDGTDDSGLFVKYLQRSGGYYIDVGASQMIADGKIKVKHGQEITEITAHGLSFADGTSLEADEIVFATGYQNMRSQARITVGDEVTDRVGDVRGLDKEGEFRTIYRRSGHPGFWFFGGNFPLCRYYSRLLALQIKAIDTGVGARESGHYKVREGGGSKPSDDEVLVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV11</accession>
    <name>A0A9Q8UV11_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767834.1">
        <property type="nucleotide sequence ID" value="XM_047911920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV11"/>
    <dbReference type="GeneID" id="71992650"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12772"/>
    <dbReference type="OrthoDB" id="2426273at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="34208" checksum="BDA93ECB4D3AA5D0" modified="2023-09-13" version="1">MGARAVGHRRVSVASDEPLCIAAFFALNVGRVRSSSRELSKFVLCDIDLRPVWEKLRPMLGFAHGVDDIEKTTMHMEEVWRQIEERGPGIPQEVIFHKLDRLQSRGFRWAPATLQQAPQDAFNLFAEGLKFRPGKMSADGLSVKCSGFGIRLCNRLVQLPMSALFCKLYHARQLRVMLPDGRWLFSQERLDLLARRPKGVHEPADQRFLKWLERARSHNLLLVLWTHLEDIALQYLCGSLVRLLEARIMDWHLITQKPIAESFQGNGLLCYAKHADQKLYHSTTIVDILPMDEDECIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVD3</accession>
    <name>A0A9Q8UVD3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768240.1">
        <property type="nucleotide sequence ID" value="XM_047911912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVD3"/>
    <dbReference type="GeneID" id="71992642"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12764"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21958" checksum="01784DB51FF3F093" modified="2023-09-13" version="1">MLNQSGFRKNSSTKTLEPGCDFFDIGTNFATLNYPTDILEYVRSGQVKVHRENVSHLSNHAVHLENGTILESNGIIASSGWLWRPTLDFKDKHLHTDLGLPSIDYTPSQTEHWAALDRKADAHLFKQFPMLKARPRPPHSEDVRRDDQLNDLKPREKKPIYTPQRFYHAIIPPPPTSPTAPSHSSATVRTCPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVI8</accession>
    <name>A0A9Q8UVI8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768405.1">
        <property type="nucleotide sequence ID" value="XM_047912288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVI8"/>
    <dbReference type="GeneID" id="71993018"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13140"/>
    <dbReference type="OMA" id="PALYWIP"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="511"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="702" mass="76372" checksum="064FAA25053FCF84" modified="2023-09-13" version="1">MAKVKNFVEAAKKDLRTDYNWNRAARLSVKCARALPSASYHYAIDKVPIIGWLPKYDWRWLINDLISGTTVGLMLIPQSLSYAKIATIPVENGLMSSWLPALFYAFMGTTKDLSTGPTSLIGLLTEEQVSHFAPEDGSGQYTATQVASGMALWMGVFGMILGFLNLGFLLDFISLPILSGFITAVAITIILGQVPSLLGEDKGGESTAAKLHDVFSKLPTANGYACAIGFTGLLFLTVIEKCGKRWSNKNKVVWFITITRAFLCLVIYTGVSYAVNKKYDDSDDYLFGVAEVDATGIPKPEMPPSSLLTQLAGRSIAIFIGSGIEHVGIARAFAVKNNYVSDQTQELSYYGLTNFVNSFFHTMGVGGAMSRTAVNSACKVKSPLSGIFTTAVVLVCIFKLSSALYWIPKATLAAIIISAVWPLISSPKVFYTYWKTSLADWISSMIALWVCLFVSTEVGIASAVGFNIVYVLLRQVFTRISHAGADSDIELQHNVAPINAGTTALGGIPAGFRVFRLNESFLFSNAYRIATSMTDAIQTHHAPNYSTTRGAEAERNWSVAGERRIAKLRRAAGISDPNTLPPIRVVVLDFSKCNHIDSTAVTQLKNFLVELKKYGGDSVQARFVAMMGYVRERFERAGFLLVRDEEGGSDPEDVNEGAIAVRVYGNVGQALIARVEDDGIGFLEKEKADVEAREVEGSDGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVK4</accession>
    <name>A0A9Q8UVK4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Negative regulator of mitosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13253</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768419.1">
        <property type="nucleotide sequence ID" value="XM_047912401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71993131"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13253"/>
    <dbReference type="OMA" id="YIGTMDS"/>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000217">
        <property type="entry name" value="20S cyclosome subunit (APC1/BimE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="7">
        <location>
            <begin position="30"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="8">
        <location>
            <begin position="1755"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="512"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1966" mass="216051" checksum="3D1C628CC1C7EEF4" modified="2023-09-13" version="1">MAAVKSLGVHTPAALSYLVDEGFLPPDPRQDQYQWTTWLTTEGGEDVEEELLTTSRVVVWSRGKLIRNVYRFDGEPEDVLQAVLTSFPLNSPASAERHPLKAEATLLEASIRPHLATETGNRTHQPRPTASGRALVVLLKTKAHIYFLSGSNHIVDLPFELERAFAAPRGIVLQRKRTAQPSLPPTPQLPRAPPNSFFFSSQAQQPNASFRHSLSPSLVKSFAKTNFAQVKPYQPSPLGAITRLDALFQEVITSSGTLIDEDVTNIYSLTDPLSDLGVVTFSLQHHRPRLYSKSQAGLSVEFEGLDPAEEVFYVSAQDELDQQQIDSRGVLTLLATFNADISTVTIWHGWYVEEKSLKELMKLHADQKEAKARRRSSFLNAGIGTGAATPGLRRRDGTRESFAGGGVLPGDPAISQATALSRNLTRQEEEQAMASQMDPDYQPVTSQPVREPRRVSSMNADVRASQTTVNASFTGTGGRRATSFGGPNTRRSLTHRKSRGSTPGSAYGQSQGDDETMDVDDTFEFDNDESSDDILRHMRATFEASGMDTTFGSADEGFKRELVVRKIHSFPLGVSTSSQGTSRKSADTLKLATILEPNDGRAADHKLGLYLHDMVTGDVQHVLLKIKQRKLWPEIPGSDLLAIPLLVSEEQLHPCEDILKLQDSRMSGVLCGRSRGMFLAAAAHLICPLPTPAAYKVYNSLDVPASNGDMETGKNRVLGQSLGFAKLKHAGIKGTYDEVSKDGIHHRLELQFRPRGSVVQELLDLCSLVLPQHIAVDLSKTWCVCHARVNQETGTLRGTKASTEMIALVAALFAVVIELLDSKARASLNLSGIAAGRSSGMIDEAAYELRRAEHDRTIRTASAWSWLPPKRRSPRRRSSGSIDRGKDQMLVIAAALADEISTTATAPSISDKPSKPDCAEVAAKLMLVLHIYMQEQKLNVLCKPQHHSSIAAVIAQLGSWLNLSDWSSGHRTYLNLEGASDELWAYVSTKKSHEVGFANLEPPLSVFAWFEQSLQAGSAPHMPTVSTIAAMGTGAMRRSNEASRMNKMTPRLAALSAMLEHSQGLSAHPVAVVEGLFKHGLTFDILEALPESMAAPFKEAIARCEKTPPTTWLDDLLQLVGRADLANSKMQILAMAKAPPNALITTRDVTTACSAVEHPTPHGKTKEAGRHSVSQLIFHEDRRLVDATSLMHFNSIQVAQCPKQPEWDEAVHFEIQRKVMHFVTIRMIALPAGDGMIHFDSQAPLLTEKYHLPGFNSSCLMQPMGHTMTTDRSGLTEEKVNWAYFHAGASAGLRISRHAEGIDTSWIAFNKPNELTNRHAGLLLALGLSGHLRQLAKWLSFKYLTPKHTMTSIGLLLGLSASYLGTMDGLITRMLSVHITRMLPLGAAELNVSPATQTAGLMGIGLLYYNSQHRRMSEIMLSEIESMDVEDPDSGPDPLRDESYRLAAGFALGFINLGKGNDLRGLHGMQLPERLLATAVGPRPVHAVHVFDRATAGAVMATALVFMKTGDRAIANKVDIPDTEAQYAHVRPDVLMLRAIARHVILWDDIEAKGTRDDGYAIWIDENMPTCYKSRIMQVARDFSITRAINSYHIPVFNIYTGLAFALGLKYAGTGNTLARDEILSVLKIFYRFDAAEAYFFDAKLGRSALKRCIDVLALSAATVMAGTGDLDTFRWLRRLHGRTDPETTYGSHLAAHLAIGVLFLGGGTITLGTSNLAIASLMVAFYPLFPMDVHDNRVHLQAFRHLWVFAAESRCIVVEDIDTQRPIHMPIKLLMKDGSRKSMQAPCLLPDLDSIKSVQTDNSAYWKVTLDFVGNPDHLTQFRKDQRVFVRRCPATEAHNSVFTATLAALTDTVSTQASSQQIWNVLANLPAFKDLDRADFELLLPPDIQSSVYSNERSTVVDDRLVLNSAVASNDGDALWNLRVLFAWAEKAKQEGDGKVRWIGEEVIEALKAGIEERNRPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVW3</accession>
    <name>A0A9Q8UVW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768767.1">
        <property type="nucleotide sequence ID" value="XM_047912944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVW3"/>
    <dbReference type="GeneID" id="71993674"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13796"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="46"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="946" mass="106702" checksum="8F921F30F54EECF4" modified="2023-09-13" version="1">MAGRPPGTNNTKRFAVELRRSKLAEGHNDKRSIPDQTVQLRLRRADSSRITRHEQLDKLVLLSFDDFRLRQDEPSGNGHVLFATARDSAEYIAKILKTGITLNNITYHFCGHSNSQQKSRSCFMYAASKAEIAAKIEGLRDFSKLKSGGKKVKRIGLLFSTADIAIELSPDRCEDIADIVYHDYTFTDGCGLISKQLAREVARKKHIVHRNMRYLPSVFQIRYRGYKGVLTLHPALLGKVQVQFRDSMKKFGDVKDHSFAVAEYSKPYNFGYLNDEIILLLHALGISSDTLLRKQTGYLNFLKNVSLCEPRTSFMFLCYQGEMELAERLLLEGPDSVRSTCGRLVRAEYTKMLNKREEQRCRIMIPKSRLLFGICDPFGKLKAGTCFVRITDDCDGVAKTIIGTEVLCTRHPTLQFKVVDCPELTHLVDFFVTWDPDIIPRRLAPAAEYPGVKEKAHFGMIAGDDQAEFFAKSNNTSLGRVKNLYLKWARIKGPLSEECQQLNRLFSQCVDGNRIRVPQALEDPSEASTETHPFILDILHASARAIIDIALEKDFDYEEDTYGVVDLLAHRNELAMSESELIQLVLRACSRLPVAKGTLSLIMNGLLRSELLTPGEVHKFRLHGANLHWKPVFQSSSDRMGRFLSSAARALQSFHKKLIILQPDERLILMIYIPQKIENASEVDVGEEVRVFALPRSSGTDSVNYRVTPTKKHYRLYCDDSTFQLYESKGSNTFVFLNRGQLDPSAFLNTKNESERRAKKQETFDTGVNAECRASVALNKISAPIQKHEIYVISNRDVESMRVLDAWLHFVDTEEVLPLFDREPSEYTVVTAADLDRSTLAPLVATVVIDRDTVAVRGAGGIDDVRQSLELLNEVGQKTQLLDACTEVLAMSMDGTCQIPGKEILLLLLDFLPIAPFLIETVLDSDLWKRDTAVVMDAAAEIFPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW42</accession>
    <name>A0A9Q8UW42_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768992.1">
        <property type="nucleotide sequence ID" value="XM_047912586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW42"/>
    <dbReference type="GeneID" id="71993316"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13438"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="70" mass="7308" checksum="5D0EA7357D7244CE" modified="2023-09-13" version="1">MASLKQNKGSKNNEPNTPTPVAALVNITPVVTAPVAPIAPLHMPFGYGGYPPPGYAPPPPYRYGAYPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW54</accession>
    <name>A0A9Q8UW54_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Efflux pump FUBT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769050.1">
        <property type="nucleotide sequence ID" value="XM_047912758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW54"/>
    <dbReference type="GeneID" id="71993488"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13610"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF24">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="478" mass="52572" checksum="6D1DC7AEE10F9A84" modified="2023-09-13" version="1">MGKIAGITFPISLFWFAWTTYPSVHSTVPALATSLWGWSFAALIQMSFSYTEDAYKQYSASALAVLGFVRNLAGGGLPLFGNQMFQNEGYQWTGSILAFLALLMVPTPFVMENYGERLRRSCVTQPSLSWHPGQYLSLLAWTNAASSFRFFTTTDLRVRGAAQSLVYMARFEDFSGVEVTVEINGHALRYRSKQLLHGEEKRVEGVGNIVAKFFHGKITHVEKRVEPSPEMQLLQAFATPDDHDQDAASPADAPTNGPGTSNTAPRNSKLAKAEQHKSMSIPSDTERYISQQALFKPQAKLGRPGLSHRVGVVPAATVGERNKAPGILVVRTGEPPRDQTDQNKEDRASGPVVGPSSNTQGKQPAHHISDRTAPIPTTGPAMPVVLLQKATPIDANTYAIEFRYRSVHKSKKMFEAINIADLATRDIREQCVEDIHALQARAAATPPDPEPVSLAPRLKRKRRDSEEGGKDNPYMVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWE6</accession>
    <name>A0A9Q8UWE6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769276.1">
        <property type="nucleotide sequence ID" value="XM_047913587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE6"/>
    <dbReference type="GeneID" id="71994317"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14439"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057654">
        <property type="entry name" value="Znf-CCCH_tandem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25542">
        <property type="entry name" value="zf-CCCH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25543">
        <property type="entry name" value="zf-CCCH_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="598"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="621" mass="69996" checksum="4ED67C032F70D4AC" modified="2023-09-13" version="1">MPSDRELDQAATDLQRFRVSQEQQTKSQDDILQQYQTLIQDYRRLQADYDEARDSRDNYKRLSKGAERNPFALVLIDGDGYIFDDHLVGGGVEGGSKAAQLLNDAVKRSLAAKGLEDCRIMVRVYADLVALSKAVSKVKLCGAEKRALAPFAASFTRTNELFDFVDAGELKENTDFKLRALLRQFIDNTQCRHIYFAGCHDVGYVSDNFAMQRLAVSWFPLTMDTARPKQPLTTTQVSELMPHVNQRDRITLVHNHAFQQEFQKLGLPTEHLLPNVFRTTPLGEQSSTKPTPLQASNGATPSDSAPICFFFQKGRCTYGSGCKNRHVKAAIDDIKDWRQKSSTPHAARPVGKSDHDSMGSRPDSRRSMTQEFDQVQRRWNDSPHGNGHARTQSFEAEFEALPRPEEIPRNKIAINRHSKRLDPYMSTTPEERAAFLAYVAKGKLCNNLHLTGRCPNPQDCKYDHCPIDEVTRKCLRAFAFNTPCDKNQYGSCRNVDCNHGHVCQRSDCRFRGGKSNCRFPSEVHTIDYHATDFVDGLQEEHGDLMAFSGSYSTTPSTRSDYGSGYANGKAVKSLETEAHDDIDVLVDTVRTGPTQEALRYAGSNEEQDQEPDDTPTWDGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWT3</accession>
    <name>A0A9Q8UWT3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_14297</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769709.1">
        <property type="nucleotide sequence ID" value="XM_047913445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWT3"/>
    <dbReference type="GeneID" id="71994175"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14297"/>
    <dbReference type="OrthoDB" id="1560166at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08278">
        <property type="entry name" value="benzyl_alcohol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF2">
        <property type="entry name" value="GROES-LIKE ZINC-BINDING ALCOHOL DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="35"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO25343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="397" mass="42426" checksum="01690E5CFD9D966B" modified="2023-09-13" version="1">MAARPLRSATAIEQYASMTSSQAIVASEPGPEHHGGDNWEMTDIRVPTELKDGEILVEMVASGICHTDIALTNPHMGQTFPMVAGHEGSGYVKAVGPNVTKPVKPGDPVLLSFDSCSNCKECHSKRPAYCDTFAPMNLFGESDVFKGSAETQSIGAKFFGHSSFAKLSIVKETTVLPVTGLIKNDDELKLFAPLGCGIQTGAGAILNLTKPGPDDIVMVCGLGGVGLSAVMGAHIAGCKQIIAVDKNQARIDIAIAQFGATHGLNTSGLEDLTAAMKHIAGGRGPNIVVETTGFPLVLESAYYATDTRGAYVQVGGPTKPDYRFALDLVQHLFRGVKLWGCVEGDSFPGEFIPQLIQYYREGKLPVDKMVKYYDAKDFKKALHDMHAGETIKPVLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWT7</accession>
    <name>A0A9Q8UWT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769696.1">
        <property type="nucleotide sequence ID" value="XM_047913475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWT7"/>
    <dbReference type="GeneID" id="71994205"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14327"/>
    <dbReference type="OMA" id="MSRVANW"/>
    <dbReference type="OrthoDB" id="4590138at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="171" mass="18644" checksum="E6C211459F083A20" modified="2023-09-13" version="1">MKLPYAIIISISIGLLALLAGLYQQGLLNISQESLMQRLSLRRLAFFPPTPTSRPIAKSFSSTTATMSSNSQPTKDDQPLLDSNGQPLGLPQPSQGSDHKLDLSSGQGSISMDHLGPLVVNKDGSLSRISNWEQMTETEQKNTLRILGKRNQLRTEDLKVKEAEQGKVDGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2018-12-05" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>P0CU74</accession>
    <accession>A0A9Q8PJC7</accession>
    <name>CLAB_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Scytalone dehydratase-like protein claB</fullName>
            <ecNumber evidence="4">4.2.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cladofulvin biosynthesis cluster protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">claB</name>
        <name type="ORF">Clafu184392</name>
        <name type="ORF">CLAFUR5_12909</name>
    </gene>
    <organism>
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2014" name="Mol. Microbiol." volume="92" first="10" last="27">
            <title>Functional analysis of the conserved transcriptional regulator CfWor1 in Cladosporium fulvum reveals diverse roles in the virulence of plant pathogenic fungi.</title>
            <authorList>
                <person name="Okmen B."/>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="van der Burgt A."/>
                <person name="Cox R."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24521437"/>
            <dbReference type="DOI" id="10.1111/mmi.12535"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>Race 5 Kim</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2016" name="Proc. Natl. Acad. Sci. U.S.A." volume="113" first="6851" last="6856">
            <title>Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Saccomanno B."/>
                <person name="Vaisberg A."/>
                <person name="De Wit P.J."/>
                <person name="Cox R."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27274078"/>
            <dbReference type="DOI" id="10.1073/pnas.1603528113"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2014" name="PLoS ONE" volume="9" first="E85877" last="E85877">
            <title>Secondary metabolism and biotrophic lifestyle in the tomato pathogen Cladosporium fulvum.</title>
            <authorList>
                <person name="Collemare J."/>
                <person name="Griffiths S."/>
                <person name="Iida Y."/>
                <person name="Karimi Jashni M."/>
                <person name="Battaglia E."/>
                <person name="Cox R.J."/>
                <person name="de Wit P.J."/>
            </authorList>
            <dbReference type="PubMed" id="24465762"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0085877"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>FUNCTION</scope>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2018" name="Mol. Plant Pathol." volume="19" first="369" last="380">
            <title>Down-regulation of cladofulvin biosynthesis is required for biotrophic growth of Cladosporium fulvum on tomato.</title>
            <authorList>
                <person name="Griffiths S."/>
                <person name="Mesarich C.H."/>
                <person name="Overdijk E.J.R."/>
                <person name="Saccomanno B."/>
                <person name="de Wit P.J.G.M."/>
                <person name="Collemare J."/>
            </authorList>
            <dbReference type="PubMed" id="27997759"/>
            <dbReference type="DOI" id="10.1111/mpp.12527"/>
        </citation>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="2 4">Scytalone dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:24465762, PubMed:27274078). The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG. The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078). This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078). The cytochrome P450 monooxygenase claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pigment biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="3 4 5">Expression is positively regulated by the transcriptional regulator wor1 (PubMed:24521437, PubMed:27274078). Expression is down-regulated during biotrophic growth within tomato leaves (PubMed:27997759).</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the scytalone dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767846.1">
        <property type="nucleotide sequence ID" value="XM_047912057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CU74"/>
    <dbReference type="SMR" id="P0CU74"/>
    <dbReference type="GeneID" id="71992787"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12909"/>
    <dbReference type="OMA" id="ARIKTQH"/>
    <dbReference type="OrthoDB" id="5281072at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030411">
        <property type="term" value="F:scytalone dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006582">
        <property type="term" value="P:melanin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004235">
        <property type="entry name" value="Scytalone_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049884">
        <property type="entry name" value="Scytalone_dh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02982">
        <property type="entry name" value="Scytalone_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024851">
        <property type="entry name" value="SCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000445894" description="Scytalone dehydratase-like protein claB">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P56221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="24465762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="24521437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="27997759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="27274078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <sequence length="162" mass="18617" checksum="03E5BFB36F836722" modified="2018-12-05" version="1">MTRQAVPKPAYEDLVDCQSAMFEWAESFDSKDWDRLSACLAPTLFLDYSDIMGKKWDALPVEEFIGMASSPHFLGNARIKTQHFIGASKWTQPDEGQIVGFHQMRVAHQKYGDDELKQVLYHGHAHGKATTYYRNVGGQWKFAGLVPDVRWTEFDCDKIFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXN7</accession>
    <name>A0A1P8YXN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp51</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 51</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp51</name>
        <name evidence="3" type="ORF">CLAFUR5_12564</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943102">
        <property type="protein sequence ID" value="AQA29273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXN7"/>
    <dbReference type="OrthoDB" id="3628044at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573456" evidence="1">
        <location>
            <begin position="18"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="238" mass="25433" checksum="9C89C7760237BA7A" modified="2017-04-12" version="1">MPSILLTLASLAATITAQALSSSETFVLYPYITSGELTGPYPNSAIDRDQPLTGSSGRAGGTFTTDCFNRFTFTAYVGTHCTGDQCGYNRWELNASYPSAGEDGYTLASYLGGGPLDSFLIAPKSEVDAEGRRDVGWTGHVDECGVGFPTSGLKLEEGSEGIVHLTYENQEDGTDVFGTFFTCWVEGNVYGPKLFYRNSEGTTPEGCAELLLVPRCTDDERLADANVVSQCYQGGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5C4</accession>
    <name>A0A9Q8L5C4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755546.1">
        <property type="nucleotide sequence ID" value="XM_047901126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5C4"/>
    <dbReference type="GeneID" id="71981856"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01978"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="513" mass="58429" checksum="D98E39AEA4845A88" modified="2023-09-13" version="1">MPDTTTSKAAHAVWGIAELLEIIICQVEPRQIRELKLVCKAWRDKVTMSSAVQRSRVVRCYGWLYEYDGEESETMDLHRHMEVVSGELDSGLAPNYDATYWLRVNPLFDRVHANYFRDLAEGTDNIRIMLGLSSFGSEKYDDAVNQYVTEPPSDCIALRTISWDSDGNEWDVLIQDVLKAHQEFVGSQTVHLRKDDPEDFDHQLATEVWASLTINGETAQKAEDPEDSAAAKKYLQKPLSRYRRATHRPGSLLDAALEKDRALTTELCDMAAAQKVFDTNELLEIILCHVEPHQLPDLKRVNKTWRATIKCKAVQRERAVPSYESNDPHPKADLTSMGRTDLELAINQVFLLPTLVVPQYDSTDWLRLNPTFKLVHTHAHTHDDGTKAYQVFIHLPASHFAPALRHAHEYITDPPCRSMALARMAWNKKLDCWCVLENHQYFWADNYEGLKVEDLLAVRDQMNLAEPPSWRLQTAAGLEVVATFIVESLSKGECDAVDQAYLLNQTAAIARWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5D8</accession>
    <name>A0A9Q8L5D8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oryzines biosynthesis cluster protein J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755576.1">
        <property type="nucleotide sequence ID" value="XM_047901378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5D8"/>
    <dbReference type="GeneID" id="71982108"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02230"/>
    <dbReference type="OMA" id="DIKTHEQ"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="94"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="193" mass="21361" checksum="FAE87615AF58BB0F" modified="2023-09-13" version="1" fragment="single">MADDRKPTNNQLAVDLPGPTAYWTGHNETGKAIVHSKHPVDWVKYDDDALAMSVAFTTTFPANLNNDADVAEHEEKQKSGKLGLVSKGGTVLRYVDFKPGYTCMMHRTQSVDYGIVLEGQVESILDSGETQLLKRGDVMVQRATMHAWRNPSETEWCRMIFCLQDCQPVVVNGERFGEDLGRGTEGLPSSGND</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="UBC"/>
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    </dbReference>
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        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15548" checksum="6CEE7AB1F2F65226" modified="2023-09-13" version="1">MGAKVPRNFRLLEELEKGEKGLGAEACSYGLDEGDDLLMTNWNGTILGPPHSVHENRIYSLKIICGSNYPDSPPEVTFISKVNLPCLDQRTGKVDLTKLPTLSTWKRDFTMETVLIEIRRYMAAPANKKLPQPPEGTNF</sequence>
</entry>
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    <accession>A0A9Q8L724</accession>
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        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </feature>
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        </source>
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    </evidence>
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</entry>
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    <accession>A0A9Q8L739</accession>
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        <submittedName>
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    <organism evidence="5 6">
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
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    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8L739"/>
    <dbReference type="GeneID" id="71980755"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00877"/>
    <dbReference type="OMA" id="SYMERAG"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:isoprenoid biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF44">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="540" mass="59740" checksum="AD16B0C1B223CCD1" modified="2023-09-13" version="1">MSTTSLNSESSAAAQTASRAAYLHAHAHAHAHVHKPEPKVRYSLYPPTFAEANHSSLGGAQPQHGQADARHTKSQRDMSAPAQATALPSSSSTTTVVATAQPPPPYVNPASIPVRTSSHRAVSNGSIDYRSDRTTTSPKSSSGPKKHRSLGSVPENRKLPELDEREWMAQSRGHRLTANPSMASYTYTHNHTQHNGADKLSPPTIINSDLINGTTSWGTEKENILKGPFDYLESHPGKDIRSQMIAAFNSWLQVPPPSLEVITRVISMLHTASLLIDDVEDNSQLRRGIPVAHSIFGTAQTINSANYVYFCALQELLTLNNPEVIKIYTDELLNLHRGQGMDLFWRDTLTCPTEDDYLEMVGNKTGGLFRLAIKLMCAESPSHNLNHHSPDDASLTDYIPLVNTIGLLFQILDDYRNLSDTTYTHNKGLCEDLTEGKFSFPIIHAIRADPSNLVLINILKQKTTDDEVKRYAVSYMERAGSFSYTRRILRGLTKKALGLVDEVDGEQGKGEMLKGMLERLRWISTQGSVRVRDNSRPRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7A8</accession>
    <name>A0A9Q8L7A8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cell division control protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756534.1">
        <property type="nucleotide sequence ID" value="XM_047900899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7A8"/>
    <dbReference type="GeneID" id="71981629"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01751"/>
    <dbReference type="OMA" id="YMNILLD"/>
    <dbReference type="OrthoDB" id="5357220at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012535">
        <property type="entry name" value="Cell_div_Cdc14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08045">
        <property type="entry name" value="CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32731" checksum="471F277B74BB8A65" modified="2023-09-13" version="1">MESLLSPSFDNISSRDSAKIRKGVRQIEGLLAQICLSIAGSRSPHKRKSSALDGGGKQQGQVKALGDLRQDPAYREFFRLQEGFQWNVASRIMSTLECLMGMGNPSDTDLLILAALELLQGVLLLHPPSKCLFGRETHMNLLLDLLDSANPPRIQSQALLVLVAALLDCPRNTRTFEAIDGLLTVTSLFKSRSTTKEVKMRSLEFLYFYLMPEAAVSPMSSASAPNTAILHRDLHRHESAFAGHARTHSGDTMDVDYEDTDIRTQYDKQQLLGQYLRNVGELVADLQDTAPFGVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7D9</accession>
    <name>A0A9Q8L7D9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="6" type="ORF">CLAFUR5_01771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7D9"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="254" mass="28409" checksum="B04A526C0A25B35A" modified="2023-09-13" version="1">MAESNSEEAFDLFQEPDDFYQKEKPPTQVQHETLNGDTLTLRLVGQNPLWGHLLWQAGRTIANYLEEHKSEVVQNKTVLELGAGAGLPSLICGINGAKAVVVTDYPDAELIENLRLNVEGCASLPKASKVRAAGYLWGADTAELQNLVPEMVQEGGFDLLILADLLFNHSEHTKLLQSIQRTLKKAPDALALVFFTPYRPWLLEKDLAFFALAKEGGFVVEKILEHVMDKVMFDEDPGDELLRRTVFGYRLTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7L4</accession>
    <name>A0A9Q8L7L4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01823</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756617.1">
        <property type="nucleotide sequence ID" value="XM_047900971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7L4"/>
    <dbReference type="GeneID" id="71981701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01823"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="68"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="457" mass="51325" checksum="E4E5CC318A197D88" modified="2023-09-13" version="1">MKALRLIQSRVHHHRVIGKLSTSPHIRTFSASAMVKGDPFKPAQRVAGQRQDVWSIVNEAAQASSVQPMVNMGQGFFGYNPPQFVVDAAKEALDKVECNQYSPTKGRPRLKKAIADAYSPFFGRTLNPDTEVTITTGANEGMLSAFMGFLEQGDEVIVFEPYFDQYISNIEMPGGKVVYVPMHPPKDGNTKTTSASEWTLDIKEFEAAITDKTRMVVLNSPHNPIGKVFSKEELKAIGDICVKHNIIILSDEVYDRLYYVPFTRMATLSPEIAKLTLTVGSAGKNFYATGWRVGYLIGPEHLIKYVSAAHTRICFSSVSPLQEATAVAFEQADAHKFWEMSKTEMKAKMDSFNKIWDELGLPYSDPEGGYFVLVNLSKVKLPEDYDFPSHVASRPRDFKLSWFLIKELGVAAIPPTEFFTDANAHLAEDWLRFAVCKNDDVLEQAKERLRGLRKYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L872</accession>
    <name>A0A9Q8L872_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ENTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756985.1">
        <property type="nucleotide sequence ID" value="XM_047900281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L872"/>
    <dbReference type="GeneID" id="71981011"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01133"/>
    <dbReference type="OrthoDB" id="44015at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.150:FF:000004">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000025">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="4">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="515"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="436"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="558"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO12619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="637" mass="70958" checksum="376AA801D5F73628" modified="2023-09-13" version="1">MSLANHRSHPAMSSSFEKSVKGGTKVKLAPPKSKYVEHILLATQSGEAGVAEVFRTLTHRLRDSTWTVAFKALIIVHLMIKEGVQDVTLSYLSVAPQQRLAINHFTDVQTQGQNIRVYAEYLLARAKAYERAKCDYVRGGEGRMKRLSVDKGLLRETEVVQDQIKALVKCDLLQNDVENEISLTAFRLLTRDLLDLYNVENEAVMNVLSHYFEMSRPDAERSIRIYKIFCKQTEQVVQYLSVARQFEYATRLEIPKLKHAPTSLAASLQEYLDDKDFEINRRQYLAEQDARKSGKSVSKPSQPASRPATTTATTTSKTWTPFDEDNKAAAKATTTQPTTGPKQDLIDFFESIDQNQQTMQTNPFLQQQQQQQAPQLQQQMPQMTGYQQPQQSVGYQHDPQQAMNGYGVNAPSTNSYGQPQPLQTQYTGAGFGGYGPQPTQQQTYTPTGFGQEQPQYANAPQQQTQPPVPLQPQSTNPFRQSMMATDSGFGALAQPQQQAQQPLHRQATNPFAKSTLQSLPENGPSPPPTQQQQKTASPFAPQPGHHPQPLQPQQTGTNPFARNVTPSQQPAASTTSPLQVQPTGSTNPFRQSMFVNQQTGQGWQHSQQTTMGGLESLETVPVFPRPGQTSQQQSPWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8D9</accession>
    <name>A0A9Q8L8D9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBZ4-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757151.1">
        <property type="nucleotide sequence ID" value="XM_047899503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8D9"/>
    <dbReference type="GeneID" id="71980233"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00355"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03833">
        <property type="entry name" value="YwbE family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069:SF1">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="19429" checksum="7F911EFE2F3F7918" modified="2023-09-13" version="1">MNRPKNRQPRPPRDQPRGGRGGGNPRNGTRPEYHAVPNKQQVVPGAGVFIVLKADQPTGRETLGVVQDLLTRGDHPRGIKVRLADGQVGRVQRMASASGDSRPGGMPSLGTIRRRDTTENLSEPPARSLADFLPPSTSENTAETGLSSELTFTTATASCPICGQFDGDELAVSRHVDEHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8I9</accession>
    <name>A0A9Q8L8I9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757179.1">
        <property type="nucleotide sequence ID" value="XM_047900050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8I9"/>
    <dbReference type="GeneID" id="71980780"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00902"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="323" mass="35529" checksum="2650837B33497D5F" modified="2023-09-13" version="1">MQASSSTSPAAVEDTLDLVHRALTVLNGPVRELDLLFGDIYDAAYELEEYEAVRGAVSILLNDSRIPTLHRAQLHIYMVTLEREDEHAWKQFLQAEAALAEIDKVQVKRGLHGHPRVDAVKKGLEEYRHFFDTGGHGYGLDEKISRPKNAVQDLLLRRKAEEEEEERAEAAKKARLAAKIKTLDPAGADIRTPVKQGSVDNGDKTITPGREREPLFDRSVAPPAPPSFVSHTSSDNDYGVGAGGAVQATIQRRRKPPQLSLAPSLSRDSSDSSVLSSPYTMPGGLALRPLRGSDSDAEQNYNRILRQKSWRGPLPGDGDGERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8T5</accession>
    <name>A0A9Q8L8T5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757329.1">
        <property type="nucleotide sequence ID" value="XM_047900241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8T5"/>
    <dbReference type="GeneID" id="71980971"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01093"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="73"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="324" mass="37370" checksum="0E909DB111005C7D" modified="2023-09-13" version="1">MHTQRSLARIGMAAQAIARPRQHRYHHAYGSQQKFRTYRLLFAMLSLLRNRQPDAHPPKTEMETQGSPQISDDKFVILVGFEQKEFLVDVEVLTQGNDYFEIMFIRTLTEQGRRVLRMPSLDTEVFQAYLQYAYGRRVIVMDSEDARQSRSKAEEQVKIANLWDFANSITDVALQNATTDAFVDTLQAASVPISVATIHHLWEITHRPNPLCHIVINWFLAKSDAGPYLEKWQHRLPSDFFVDLALYYADAPMPDRPLEPYEYDRCRFHLHTDAVPPCASVPQRLQLTQENLGEELEDKRRSSSDSVTFGRGTRSEIEAARLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8Z9</accession>
    <name>A0A9Q8L8Z9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757434.1">
        <property type="nucleotide sequence ID" value="XM_047902423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8Z9"/>
    <dbReference type="GeneID" id="71983153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03275"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="62"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="17884" checksum="07075D9847EDA306" modified="2023-09-13" version="1">MANTYNNASSLADEMTKVLLHGEATSSPISITANMSCYPARHRRNRSRREDLRRHVQSNLPMGTLHTGATSAFFECATTWALYPIAKPGFWKSLRICRTIASTYLRPAVQGEVLLMECETVHVGKRIALLRATMKRERDGVALVTCEHNKYNVDADMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L919</accession>
    <name>A0A9Q8L919_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757526.1">
        <property type="nucleotide sequence ID" value="XM_047902585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L919"/>
    <dbReference type="GeneID" id="71983315"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03437"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050440">
        <property type="term" value="F:2-methylcitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="475" mass="52478" checksum="C4D09BF8C7D3B7ED" modified="2023-09-13" version="1">MVLNNIARTALRRTMAAQPAVQSWTSRSAFNATRTYASKSASLKETFAASLPEKIEQIKMLKKEYGSKVIGEVTLDQVYGGARGIKSLVWEGSVLDSEEGIRFRGKTIPECQELLPKAPGGQEPLPEGLFWLLLTGEIPTEQQVRDLSAEWAARSDVPSFVTELIDRCPSDLHPMAQLSIAVNALEHESAFSKAYAKGIKKTEYWEHTFEDSMDLIAKLPTIAARIYRNVYKDGKVAPIQKDKDYGYNLANQLGFAENSDFVELMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGLANQEVLNWLQEMKKSVGSDLSDENISKYLWDTLKAGRVVPGYGHAVLRKTDPRYVSQREFAMKHLPDDPMFKLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEQNFYTVLFGVSRALGVLPQLIIDRAVGAPIERPKSFSTEAWAKLVGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9V2</accession>
    <name>A0A9Q8L9V2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3636334at2759"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040407276" evidence="2">
        <location>
            <begin position="20"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="657" mass="73275" checksum="27917A8D931F9751" modified="2023-09-13" version="1">MGWWRRLGAFEVRAAVACGYGCSAYNICWEEDMCTNLSVLISERSCLGYQLRVRSGLRAQSQTKSSAVWTSSDFFAEPAASTTRSDLLITHATTRLNTSCKRAALVARSANSITMAPLLPNGDYDPCSPRANNTTTTTSTPPWYPSQILQSKSSMRSTLSAPNGLSTHPYEPVLSTTPTNAQRKLPTPRSVQNFINPQNLFKEPPPVRPAWTPINGSSPAEIAARAALRLLDRPSPMPVQYPKTPTNSTIFQANYQRVIPDFDIDMNEIEAEEELLENRTTVLRLNQDWQVDKADGRMYHIGHQPGAAYSGTLANDDPDHIDIRALEKIAKLEEQWARPQRLARSKELFHLANEYIHHGKSLQLQRTSFVVEGESVICQRPGCEKALAANVYYLCMGEDTCFCLHCFEMLWEGKCTGGLPDRFGTPKAHSRRDSAVNVEIPQLDGVSDIYFEATQRVNGLQSTPEHQSPVVNVEAPKLYDELHRLDLKQSSLMQSMHAFSDDEIDPPPPVCTPKRSVSRVEQDLKDLPDSPGSLGSTDSNGKWRHPPTRFQELHAHIVPGATLSETDKAALALWKLVSMEQRRWNGHLARSDARRAFQAGESSEDLSVNITAVTPDDTVEEEALMAITGLRKKDCQGRDLSEVLKEAAYIQKQKLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA83</accession>
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        </submittedName>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA83"/>
    <dbReference type="GeneID" id="71982552"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02674"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="257" mass="28595" checksum="6B3B8A6EDB8BECBC" modified="2023-09-13" version="1">MAQTVKQEPMDDTYNDIGVSVAVDVNAFRPPPVRRNRAPTGGRTRLSGEVTDQAVTDGLPAGLVGRCYQTTVFVSSGQNFIEITHGLIDTGAMAIFISRAAVDQLGVATQSCPPKTFASSNNAYVTYQSYVRLTLHIGGVGRDVIAFVEEDNCIRHIILGIPAVELFDIKFEANYGPRCEKLWHVAEKNNRRIRYVLEQERSSAPRQVRTLDYQNGLRIATKRGKTPKEREASMKIMRAKANYKRIHGKYQHRVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAC7</accession>
    <name>A0A9Q8LAC7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758169.1">
        <property type="nucleotide sequence ID" value="XM_047901638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAC7"/>
    <dbReference type="GeneID" id="71982368"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02490"/>
    <dbReference type="OMA" id="GAYFNDP"/>
    <dbReference type="OrthoDB" id="26136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001086">
        <property type="entry name" value="GTP-binding protein GTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO13803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="406" mass="45543" checksum="0D1AA654ACA3C092" modified="2023-09-13" version="1">MHTLFGEAILSPGPKTVPPSKPNPFELSFQSSVATSYTDSSSSSNGKNDWLTQYHQAQDRLSGEPANQASNDATSRYGHAGHKGNPKLLFMGLRRSGKSSVQKVIFEKFSPAETLFLDPTTKIETAKMDSFIKFESSELPANLSYLALDFDHEGVFGSVGSLIWVLDMQDEYFQSISKLIETATFLLEHFPRINFEVFIHKTDGLSEEYKHDTFRDVRQRVQDELSDAGYGDRGVAFYQTSIFDHSVYEAMSKVVQKLLPQLPVMEALLNRLCSACRIQKAYLFDTISKIYLATDASPTFLKDYEVCSDYVDVIVDIKQIYGWQGRGSHQDGSQSQTSNSTESSAAVGESLITYDKSGNTYIYAREINEYLSLICVMGQGSTADKRMLIDYNVTILQEALQQMFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAE9</accession>
    <name>A0A9Q8LAE9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758118.1">
        <property type="nucleotide sequence ID" value="XM_047902978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAE9"/>
    <dbReference type="GeneID" id="71983708"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03830"/>
    <dbReference type="OMA" id="QEWEHTD"/>
    <dbReference type="OrthoDB" id="5320532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008402">
        <property type="entry name" value="APC_su15/mnd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05841">
        <property type="entry name" value="Apc15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="37118" checksum="19B7FF2AB985B6A5" modified="2023-09-13" version="1">MLSIPLIPPQEDSSTFLRSTYRPRAESPPPAVGQNQQQTHRQRQLRDDEKKQHNARSPLAILKAEEAAIESRKAAVRNFGSHWLRPPGISKTLQAMIEEALEREEQAEIERQEAGMRDMQAQQQLAEAQQQAQETAEEGEDGEEEGEDGEEERDLDAEIPDADATTADVTFNEDSMMEGSQVESTDQNIEDEGGNENEMEVAELTGAAQDEEELGIEMERDLDDSVPEAGSYQHTDTEIEDSDSDSEIRSSFIDRSAPRSALSDATPAGQMGPPARTAGGLQERMRAQVHAADALPRSPGSVNLSSSILDSSLLGSSPVMQRTNGGARGRGRSRRGRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAH9</accession>
    <name>A0A9Q8LAH9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758229.1">
        <property type="nucleotide sequence ID" value="XM_047901496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAH9"/>
    <dbReference type="GeneID" id="71982226"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02348"/>
    <dbReference type="OrthoDB" id="4472872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF3">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="2">
        <location>
            <begin position="9"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="11303" checksum="F652275575803FA7" modified="2023-09-13" version="1">MQHGLYWKIRKHMRYIQTKYRIFDVANYIFLALQLLLSAVFIVLGSVTGNYKVAIAVLGAISTVIGGLLAFMKGQGLPNRLRQVRDDLQLVLFEAEELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAX2</accession>
    <name>A0A9Q8LAX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758439.1">
        <property type="nucleotide sequence ID" value="XM_047901677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAX2"/>
    <dbReference type="GeneID" id="71982407"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02529"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="29856" checksum="5B91C2AFFA5CDE5D" modified="2023-09-13" version="1">MGMSAEEEVSSVVVGAMASEVLLLGGVSELLDVVEESNGLEDRVGEDVASLVDEEVAISGALLVIEFDEADPAAVEDGLELKDTIADDVASTAVEDGLELGGVIEDEVDLPAEADWLELEVPLLACTFELLDVAGEEVEVVVGADEEGVFRLKLEDELNSVLDLREVGDGSDEDEGLLAGSGDMITDELVCALGEVARPTLEVVVLEACPEERPMTDEISPSELVTEDESKLEILPSAAVEGAVWVSELFELLLVCELTVDDVVATSKEVELTSSLRQEIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB97</accession>
    <name>A0A9Q8LB97_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS-type transporter cnsO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758598.1">
        <property type="nucleotide sequence ID" value="XM_047902333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB97"/>
    <dbReference type="GeneID" id="71983063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03185"/>
    <dbReference type="OMA" id="WILPNFP"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="71"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO14232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="520" mass="57186" checksum="0A3CEBB6AA21F1C9" modified="2023-09-13" version="1">MSAHHANSERISAEDDPRDIKNAADFLDEVDEHNAVKPNRTLEAPPLVRDLSPADRERLEKTLVRKIDFRLLPAVIIMYIMNYLDRNNIATARLAGNPGLEEDINMNDSQYETCVSILFVGYILMQIPSNLFLNKVGKPALFLPGVMVIWGIISTATAAARSFGGLVAIRFCLGFIEAAYFPGCLFYLSCWYTRKELAFRSAILYSGSLISGAFAGLIAAGITDGMDGKLGLPAWRWLFIIEGAITIVIAAVCFFVLPNLPRTTKWLTEEERQLAVWRLQEDIGVDDWTSSEEQSFWQGMFLAFRDTKVWILMVMLLGIVSSASVTNFFPTVVQTLGYSKLITLLLTAPPYVLAVFVCFANAIHADKSGERFLHITIPLIIGMASFILAAATTSVAPRYVAMMLMVPSIYAGYVIVLAWISNTIPRPPAKRAAALAAINAVSNASSIYASYMYSGAPRFIIAFSVNCGTLFLAIAMAAVLRIMLVRLNHKLDRGETIDGGISGASIGEGEAMRRGFRFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBD1</accession>
    <name>A0A9Q8LBD1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758612.1">
        <property type="nucleotide sequence ID" value="XM_047902382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBD1"/>
    <dbReference type="GeneID" id="71983112"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03234"/>
    <dbReference type="OMA" id="MAWNKRE"/>
    <dbReference type="OrthoDB" id="166746at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21552">
        <property type="entry name" value="VEFS-box_ctSUZ12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="8">
        <location>
            <begin position="838"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="601"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="884" mass="100542" checksum="E981E5C075F3E934" modified="2023-09-13" version="1">MANDVEFRSFVSKVYLTRSINANSPSFLERNLRHALDSHERELARERATANSNAPAAMLEPRRTRSHAWDPPSDRIMDELMQANKAKVRIKSISLQDPARAAASSGRQVKKSQSRDQPEWLQEPDQLRVPCQVVVTVNDVRSQKRTISTAARQGTITKHGRSTFDITFKDCFVISADDLKSHTSSFTEAGHWTKALHKNHSMEFGIHCQDSDDTAEFLSQLEGRPITEFLTAPGNEGIVKCNWAGLPGLPDSEEALPLHRAKGHHEINLKYVARIDMAWNKRESPLTTYNKVLRRARNEARRLTTPSEDLERAGGKTLVKYAYRQGLETKGMPVNHLRCIFCTQEPEHATFERLHLHYLTRHDHFQYEIRLEVDHNGDDLRTIRISHEDDRPTTNEKEFEWEAPHRAFDISAHLEGTNSWTVRNTKKTNSKGAGKHHKVQPTILARPKKRDIAPEDVEEIPTCIKKRHVVPRVPGVKFYRTKSKQSVKPGTELSDSEDDVDETWQLQHQQKQRARLGASKVAQQFNELFNKHLDVEGQPQSDVLVRDAVVRFVRQHAKQLAQPGWREEFDSKLKLLQRVNIVDAATVEYCHEELSEWEHDLDGRTLNSDETEDQLPKARAQTATPSKRRVRGAALESSVADPKDVHMESPSNRVVPEPPTDTPSTKNRKRWAGGRMKSTSAEPPDPQPLGQRTLIVIRQETERQAEKSTGELPITDFTKDGDSQKPIDEIRSADLDYKKFLRVLDNDLIYIRNVDNIVCISNATVRPIVDENDWHEALRMVQAESTGPIQFQIGPLDFIMNSQARTPKKGTRKTEAPVETAKQKASIAVTAATSKRKPCVCGEFVSSKRHTIGCGNPRCYRDFHMACVQLQKRSMAWLCMDCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBU7</accession>
    <name>A0A9Q8LBU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758913.1">
        <property type="nucleotide sequence ID" value="XM_047902951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBU7"/>
    <dbReference type="GeneID" id="71983681"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03803"/>
    <dbReference type="OrthoDB" id="10632226at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="230" mass="25769" checksum="865F32A965A4DD30" modified="2023-09-13" version="1">MAATMGGRPPSTDNSKRKAAMDVATSLGAQGPRKRSKPTRKKKGDQMKKASDIFRFVDLPGELRDNVYEKVFEGRPTRLHRNSANKPLAIESGLARSNHPNKCYLIAFFNRLSEAQLAKLQPSKEKTPAKRVVRIELMFAIPAAGIETPAFGFPREVRHLPAFDNCFPLWWPISRDVNPATSTGRRFREARKIFKAILKATSEDCTKVPEWRVGGLKEDVEGEDEECGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBZ7</accession>
    <name>A0A9Q8LBZ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Utp8 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758820.1">
        <property type="nucleotide sequence ID" value="XM_047902744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBZ7"/>
    <dbReference type="GeneID" id="71983474"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03596"/>
    <dbReference type="OrthoDB" id="5330858at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018843">
        <property type="entry name" value="Utp8_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10395">
        <property type="entry name" value="Utp8_b_propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Utp8 beta-propeller" evidence="3">
        <location>
            <begin position="6"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="835"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="651"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="895" mass="98451" checksum="D8F5B31697A4FE1E" modified="2023-09-13" version="1">MSGGIEEPYAIAALAKPLDGKHGRIVGASVHSIAGSRKRKRHEVAIGVDGESVSIYHTQDQSTVSSYALPPQSYLAAPPCSIYCKRAKPQQPQRQTYLAVWDSVSRQKARVVSIKENLGKPQSDEREPRAPTRRERKLRHAQVVAIDVVPVHNTLASLESDQHPVLVSYSNGDVDCLRGDMSAARWEHKATTTGDTQIEYAVVVEYDAARRGLLKNREDVLAVLDSSADAGRTTNGPPLLCQVIRTGSQRSLRIFALRNLSGDTLQGGRSSFEDVLTYDLPARHNTGTEEAQYELHAASAMLYQRLGNRLTTYDVSGTTPEASFELGRRDGLIVNSFTRLSSATVLVVTPDKLAVYDTKYGSVLSSLAYVTQPDAAANAQARSSLAIISQFTDLNILVALSANNLIAFQVGNMLDDGRSSRAQEPVLFDVLGKGKVALLEGSELKEKKKRKWEEWKSKVDGLFEASNAEGLESFVAKMLKLDPKTQDKAAENLPSGYHDADVALWDLPSNTYDPQHVETRRASYLLRKLFAWRSLDRRSHSAGNLEITLLSRNVLRFLALAGYLTTSTMQLVLPQANDGTKRRVAPGDIMLAIADGEPSLVLMCDLISMRVHWDLPEIVQGLQTLIRSLQDKQNADMAAAQLTNGVVDMADGDVQTELDAVERELDKAENLLESGLAIRAHACRILLNRLQAFPQRDVKQVMHTMLTHADLIFFLCLLRLELADGGWTQRYLEQDVGEEEPSLDVPNAQDITASNLAIRTIADLFDCAVDAIGLSGWLIGLSADIDGTEQLLQELKNEVSATVEGLFEAELLTNLLSNVKKTAAVLGEQQRSTLKRKLQTDEDDSVEDKLMPVGGRPEPPIVRTWGTKDGRKSKAAIAQQKSRAVGKYSFEQIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCQ4</accession>
    <name>A0A9Q8LCQ4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759477.1">
        <property type="nucleotide sequence ID" value="XM_047907327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCQ4"/>
    <dbReference type="GeneID" id="71988057"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08179"/>
    <dbReference type="OrthoDB" id="5428245at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="323"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="595" mass="70344" checksum="4A0A829387AD4988" modified="2023-09-13" version="1">MSRYRSSGDDLAYGEIPQRWDRERFERFSRGPPPPPARGYEEDIRFTERERPGRREIDIAIADREPSRGPRPWERERYFEEDRARSRPRRRTDRELFGDMDPREVAEMALTPYRPRDDFEHGRPPPRPGLVRRQSSLDTFDRKPARYEREEYRIPAYQPVPLPIRRSRDAWEEERYRDEPEDYREVEIHRERSVHRRRPPKSERSVKDEKKETHYHHSHHSDETSSSSSSSFTEIDEVKSVKSRAPSKAASKAPSKAPSKATSRAPTKVSSRRSRAPSVYESIHETEIEEDIIEAPPPPQSVHETSIHETAFEESVREERRFKKGKTRMPKRLVRREAIMDLGYPFDEEDDFFVLRIALEKEQIDEVIHISETYKDGEKKKVYHFEEKIEETTGVPPPPVGEHEHVERTEWINPPSIAYARSHRAKSVRESSPTMTSISRRSPPRSKSRGGTVYEERKTVIEETRSPPPPPPPGPPEFYEERKTVIEERAPSHNHGTLVLSEHSHRSDRDINGEIRALEAERRALRLEREAEERRDMALRLRAHPEEEYQLVEYRDRSRPREEMVVYERERSPPRNVIRVEKDRKGRMALVRSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCW2</accession>
    <name>A0A9Q8LCW2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_08558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759453.1">
        <property type="nucleotide sequence ID" value="XM_047907706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCW2"/>
    <dbReference type="GeneID" id="71988436"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08558"/>
    <dbReference type="OMA" id="EHATEWI"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO15087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="290" mass="32220" checksum="8EA45C3B82F935AB" modified="2023-09-13" version="1">MSRDSKTAADDLTRSKTTSLTNNTRPDADRLDTIPHERKETRPDFSKPLPRQKLPTDLQKTLDNEEKFWEVLSTGEGQETTDTSVRYAAYASRLRTIMLSAHRYVAYTSDIGESFRPVAHPYLIRGAYGVSWAYLIGDVSYEGYKARIRNQRVLNPETEEDKAAAAADPGRGVPAIEDYRAVMAQRAIFQGVASMGLPALTIHSIVRYSGRAMKNVKNVRIRTWGPIGLGLAAVPALPYMFDEPVEHATEWISHRAFEAVGGPKAVGKDAEGRGAGLEEKREGRKAEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD87</accession>
    <name>A0A9Q8LD87_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Patulin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07949</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759601.1">
        <property type="nucleotide sequence ID" value="XM_047907097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LD87"/>
    <dbReference type="GeneID" id="71987827"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07949"/>
    <dbReference type="OMA" id="YQNWHAS"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF138">
        <property type="entry name" value="DEHYDROGENASE PKFF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="560"/>
            <end position="561"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="606"/>
            <end position="607"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="625" mass="67656" checksum="A847E6D28F99240D" modified="2023-09-13" version="1">MRTAIPTAALYAVSAAAPPRPDASTQQLVNGNDFGLPRRNATYDYVVVGGGTGGLAIAYRLAEDGTKSVAVVEAGGFYEIENGNISVVPAYNMEYNYITPDSQWDNPLVDWGFLTTPQAGGMNQQFHYGRGKMLGGCSAENAMNYNRPTVGTLQAWAEAVDDDSYSWDNFLPYFQSSIDYTAANTSLRAPNSTVPMIKGEIGSAPLQVSYPHWASPMSSWAQLAFRELGIEDTDDQISGDLIGSQYNTLTINPKDQSRSSSQSGYLDAALHSRRTNLKVYTHTLAKQIMFNPNKTATSVRVQSGALPTSYFLNARREVILSAGAFQSPQLLMVSGIGPASQLEQHNISVIADLPGVGQNMWDHVVLSVGRQVGVETYGRLMNQTAARKAEADYASPPHTGILTNDQSDYLGWEKIPASYRSNFTAATASALDETFPRDWPEVEYEISISPFGTPSFSTPEDPIDVGYIQPVLIAPLSRGNVSISSADMSDPPIINPNWLTDPVDQEVAIAAFKRGRAFFNTSAIAPILIGDELTPGQDLPEGSSDAEILSYLQQNIGFNWHASCTCKMGREHDPMAVVDSRARVMGVQRLRVVDASSFALLPPGHPQATVYALAEKLAADILAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDD1</accession>
    <name>A0A9Q8LDD1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Citramalyl-CoA lyase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07882</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759791.1">
        <property type="nucleotide sequence ID" value="XM_047907030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDD1"/>
    <dbReference type="GeneID" id="71987760"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07882"/>
    <dbReference type="OrthoDB" id="1773at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000023">
        <property type="entry name" value="CitE, Citrate lyase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="6">
        <location>
            <begin position="13"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="35142" checksum="7C0F5314FD17E51C" modified="2023-09-13" version="1">MAATNVAKQTIRRAQLYVPGSSMRFLEKSRGIAAVDSIAYDLEDSVTPSKKPEGRQNVLEILNRDRAPGIREQAVRINAVDSGYALDDLTTILKGKNLDAIVVPKVDAPKDLHFVTDVLRQILPERHSAGSTNPIKIVALVESARSVMNLNSICAASPYLSGLTFAAEDFAMDLSLTRTPSLHEFLYARSAIVTAARAHNLPSTIDLVSTTFRGEEGKRQLREESENGKRFGFNGKQCIHPDQVGVVQEVFSPGEKEAEWAVRVVVCDEKADRQGRGAWTLDGKMIDVPVVGKAKAIVARAEVCGFDVAALKERFKDEEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE56</accession>
    <name>A0A9Q8LE56_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759930.1">
        <property type="nucleotide sequence ID" value="XM_047907893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE56"/>
    <dbReference type="GeneID" id="71988623"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08745"/>
    <dbReference type="OMA" id="HAMREDK"/>
    <dbReference type="OrthoDB" id="3649991at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="511" mass="56944" checksum="1F94BFB3B4D509D8" modified="2023-09-13" version="1">MADSKAQEAAREEQDEQWVEVAPPAYEASANGADEEGDLYYATPQHTGLNEKTASLPQEPSRPETDSTNLATVSKDDVKARQQEEAAVWYKQAPLLSEAPPLPVKEPIHVPSEHSMALEHLKHMPALPVRPKFDDEMLALQLQQEKQERAAVLPPPPHTYKITDSIDSFSYTFSWRRPLTDHPTLSITANDTSTNASHWRLNYQSKYSSRLHRYQADQARVDGDFPARQIAEIKFPEFILPGCGPTITFEAHEDAIDRKGSAHAMREDKFMKCSGWFTTQYALEVPSFGGARCTWRPAQSATDPSQPSPASTSQPQRITTGDLMAQAKRYMNDDTWTPYPNQQLIISQTNHIVATYTRAAPWAKDAGILHIVRPHDIQYLDEYIEGIIIATVAMVGMQDRLGLASSLMQASTEGVLASRRVQQKTTQSTPRSASGVVLAEEPNVQSHYTTSQPATTEYVDVAEGAVGEYKESKIQRSLRRLSDRLAAKSEALLLPQMRMREGTSVVADEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE61</accession>
    <name>A0A9Q8LE61_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04496</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760168.1">
        <property type="nucleotide sequence ID" value="XM_047903644.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71984374"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04496"/>
    <dbReference type="OMA" id="SYYMHTY"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FORK_HEAD_3"/>
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    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="919"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="919"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="629"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1098"/>
        </location>
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        <location>
            <begin position="1190"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
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        <location>
            <begin position="798"/>
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        </location>
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        <location>
            <begin position="828"/>
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        </location>
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        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
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        <location>
            <begin position="1025"/>
            <end position="1034"/>
        </location>
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        <location>
            <begin position="1042"/>
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        </location>
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        <location>
            <begin position="1190"/>
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        </location>
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            <begin position="1276"/>
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        <location>
            <begin position="1325"/>
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        <location>
            <begin position="1367"/>
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        <location>
            <begin position="1434"/>
            <end position="1473"/>
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        <location>
            <begin position="1490"/>
            <end position="1500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO15802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1539" mass="165659" checksum="BDAFA995938C6A92" modified="2023-09-13" version="1">MADAIGSRLEHTFPAFDFEDLINWPDEDADDTLDKVGSDDEPPKIDSPRWSGDNSSLCSFGSPCTEDVGARSLDFIPRATEGKRAGSAAATGVADGSQDQARERNVKDHSLHSLTADQQEQKRFRAAGLVKPAACTCRPDCPDPAYLCKQQRETLEKRRKAEQQRQRDRIVAALQAARKTVPYITIIRGKRKDNDAGPSQAPQAMEPSGPGVLAAQQPDLDLFSRSPPPAPPAPSAVTEAVAEMTMPEVQIAATKAQTPPSLALPPPPPPHSQSPPVAETTHVAEHMSLPDTPTRVTDHGTLSNIRDTNGPVHIDAPPPTTDNLAPDTDKDNLFSNDDDLFNSDIAIPRATSPPKLGEIDFSQDSYGGHDAPNEETVEIPNNSDEVFGIASVPSDDEDDQHEGYAMLRFSNSYCVITSLNLIIQRDATYLAAYRAERKKAKEEAKARNALAAYQQEPSQPSQPGDDDRFGEDLEGRPQQGLLSSFSEQGGPVAFAMDDHLSSSDRRRRRKKGNSSSANSIAPRDLYTLPEDEIQHTEPVPVNSRPDSHEWAALPVHPARPADITQISREHLIFSYNHWHDEQWILRIVGNGAVVNEVYYTKDQEIALQHDDEIWISTLKFNFELPRTEEEENEDLLDGVEAGTSPATSRIRRASSTADAEESEEDKRPKVKLKLKRPKKPTEQEPEPAKAKSAAKAKGKDKGEKSAGKAKAKDVPNGEDTTGSPEVTKKKDKGKKPKAAAPENGAESAKEPKPKPEQASPPVVPINLEPGSVLADLAPEQMPEKRKGPGRPPKNGLLSKRDESGVKRKRREYERRNEPIPDLNTLLAEVRHEQRQRDLQAKAAARGEQPPDLPMPSIESSARPTIEGGAQMPPRDSQGQESQTPLPNDAMLAFAQARPRQRSPSPIKPETEFTEEDLKKPSMTYIYIIDEILSSIEGGQADLQTIYDKIQKRWPYYKYRVGSIGWQSSVRHNLLSCERFVDAGKSGKGKFWRINFDHPLDNKKRKSPPPPNRPMQNGQMPPPYGQPGYPGNYGQSNCNGQQPYNGQGNYYSPYPGGPNGQPPPGQAPNGQYGGPQGGPSPHQMNGGAPHPPPQPAETPLTRQVNAIMNFRSHWLAGHAIDSQEYKSRELGFVRAVGYYSYVTSNGQGDRVDLVPGEDLLEPFPSMKAIFDRFLSDTADAAAAAPANGNAPLANQQQQVAPPRQQQPPGQQPQGQLTQGVAPPTQQTQGLQTQGPQLQSQQAVTQHPQGQPVQAQQQPQGQQHLTGQQQPTGQHPGPNQPQQPFPQPPPGSQPSLPREPLVGIVQPPQSRPSGNTPPNAMPPPAGTPQATTSAAAMAAMAPPVSQQVTGAVGTAGQPAPQSLPPTANGIITQTSGAAITQTPAVDASSLAPTRGNDQSLAATVPIDQASERATMPSTVAAPSDGHAKAENPAQDSASSVSTPVTSTVADTTTGSSSAATVNSTAAPSAAVTSPALPKADSAATSPLAPENSEAQSVTTPSTEPKVIDLEAPDPVPQVAGVKRAAGTDEEEEDDVKRQKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE97</accession>
    <name>A0A9Q8LE97_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ASST-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LE97"/>
    <dbReference type="GeneID" id="71983920"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04042"/>
    <dbReference type="OMA" id="WDPENEF"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
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        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF8">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040113118" description="ASST-domain-containing protein" evidence="3">
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            <begin position="22"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
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            <begin position="523"/>
            <end position="551"/>
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    </feature>
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            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="67773" checksum="EBBBACC955F47841" modified="2023-09-13" version="1">MPSRAKKAALLCCMFALQAQAAFDLAYGDDSDLTSFVTRPEIKTPKFNVTIYDQDRISPGYWFVAPYAMIFQENHAHKYYQPCQTGPTIYDSLGNLVWSGACKVRNQNTCDFRAWEFNGSLFTSAILTPFRGVDDPQGHGIITDSSFDTIGELHVPPTMHNLNMHELNLIEDGTKAMHILHEPVQMDLSALNQNVDSGWIMDIGFREVDLTTGDLVFEWWAARGGHVSVTESSVPFRGANIKREAWNWFHGNSIEKNEDGDYMLSSRFTDTIYKISGKDGSIIWRLGGSKSSFQQDFNFSRQHDARWRHHDDGTETISFLDNAADDTVSNANHSSAMIVKLDRRTMKASLLSEIPRPDGRLTRMRGNHQVLANQNSFVCWSENSYISEHSANGDVLMEAQFASHRFVTYRAYKFNFTSVPSEPPVIKAYAYGTSRATGASTTVVYASWNGATEVVSWRFKTADGTVIGEKTKSGFETTFQAGGYHADVFAEALAANGSIIGTSATSFTIAPADWWEQMPISGIPEDIQTTPNSSKNDSSPTSSSTAKPKARRPDHFYDDVLAVSLLLTIVFMLCIALWLWRCCDGGRGSIRLKHQQYSPVGDKDDDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEI7</accession>
    <name>A0A9Q8LEI7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760293.1">
        <property type="nucleotide sequence ID" value="XM_047903439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEI7"/>
    <dbReference type="GeneID" id="71984169"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04291"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="299" mass="34412" checksum="A8306A660B03EF6C" modified="2023-09-13" version="1">MVIIGASVSPQSSDREDARTWFEVVEEMVFQDDDFCYDGYSPFYIVCLYQNWDGTDPSKRRIRRFRFSTMVAVARDIADSDLFVSVLAGHSFRYLNNLPPRLAIKEMQMQFATNEGAFQADSATMCFNYLASGATAQVGMMSTLCEKFCEGQLELQHQIVLVDMGPLNLFVVSSQLFGHDIEMTPVRHALRNWIKVWNLYQDGYCYLYRHVPLVGHSLTSDNMWKRLGFLRYAPEYWQLAQFLVERISTASATREQALADRAAASTTCQQSPPSLLKQYDDTSMRQVNDLIVEFQQVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF15</accession>
    <name>A0A9Q8LF15_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760618.1">
        <property type="nucleotide sequence ID" value="XM_047903079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF15"/>
    <dbReference type="GeneID" id="71983809"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03931"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12720" checksum="9D5ACDAD23D204F7" modified="2023-09-13" version="1">MRELLQDEASLERPVANDLWGFRFDRDLASRALGNLSRTTGTSIRIRQGNLNQIYVLPKQSREDEDEIAQKVYATYDPPNVHLDVTLASDPAHHWCPIIQVLRHAWNITAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF33</accession>
    <name>A0A9Q8LF33_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein CFT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_08720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759884.1">
        <property type="nucleotide sequence ID" value="XM_047907868.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988598"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08720"/>
    <dbReference type="OMA" id="PMTKFKL"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="12"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="532"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="967"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1346" mass="147307" checksum="1A2F8D2A18BD99BB" modified="2023-09-13" version="1">MQCYTELLPPTAVTHALSLPFLNAGANNLIVAKTSLLQVFNVATFDGRDKLVLVGEYSLSGTITNLARVKLPDTKAGGDALLLAFKDAKLSLIEWDQENHRISTISIHYYEGDNVVSQPFGPSLADCENILTVDPNWRCAALKFGTRQLAVLPFRQPDDELGVEEDEDAEPASATVKRTESIAQNVNGVVEQTPYKASFVLALSTLLEDIRYTVDLAFLYGYRESTLGILSSSVQRSSALLNVRRDVLEYRMFKLELEQGESTELQVVKQLPNSLWKVVCLPAPVGGALLIGTNSFVHVDQNAKVNSVAVNEFAKLESDRGMEDQSDLNLKLEGCSVEVLDAESRQLLVVLHDGSLVTIYFQLSGRSIQGLKVSRVASESGGDLIKAAPSCVARVDDNKVFVGSEDGASSLVRWSRHTTGLSKKRSHGQMLGQTGDEEEEEVVEDDDDDLYDAAPESKKRATSTDGVVETAPSFQIQDELDSLGPINDICLGRSGEAQADRLQLMLGTGRGRSSRVSCLNRDIVPISARKSALGTAKSAWAVHAKRDDPEEDGYDNLLFAYDGQDTKIYDVDEVGYMERTAQEFEHEGETIDVQTLAKDTIIVQCRRSEIRTYDADLALSQIIPMVDEETDEEYGIVHLSFCDPYLLVIRDDSSVQVLQVQGKEIEPLEGEGDIAEKKWLSGSIHAGSLTKDEPVLFLLSAQGSMHIFSLPTLEPVYHAPALPHLPPVLSSDMPQRRAGPREALTELLVVELGTNGVDMPYVLARTALDDLVLYEPFHHPATASVDAWYTNLRFSKVPITYIPKYNEAIAQEESTRPPPLRCIEIGAYNAVTIPGSPPLLLVKEASSLPRVLEVKITNETNHVASLLPIHLDHCKMGFAALGVDGSLEEYHLPLSTWYGTGWSVQQVDLGPDDLEVRHLAYHENRGVYVVATCKDVDFYFAEDDHRHLGQSGGGQDDIALRPQVKQYSIHTVSSKTHRIIGSYDMPYLEAITALKVMPLEVSELTHDNELRILISTAAMRGEDMPAKGAIMVFNLIDVVPEPDSPESGIQLHLDAREETKGAITALAPFPGGFVGTGQGQKIMIRGLKEDGTCLPVAFLDAQCHTTTMKTLGKSGMWLAGDAWKGLWFGGFTEEPYKLTVLGKAPKTQMEVVAADFLPFDGALYILIVDADMDLHVLQYDPENPKSQNGMRLLHRSTFHLGHFATNMMLLPSSLNPFGENQTFTNGDTGDAPGESSPLFHVLTTSLTGSIGMITPLDESSYRRLSALQTHLTTILEHPASLNPRAYRAIESESFGGARGVVDGNIVRRINELGAARRADVLGRAGADNWSIRSDLEVVGGGGLGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF58</accession>
    <name>A0A9Q8LF58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional regulatory protein SEF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_04095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760721.1">
        <property type="nucleotide sequence ID" value="XM_047903243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF58"/>
    <dbReference type="GeneID" id="71983973"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04095"/>
    <dbReference type="OMA" id="MQIGLHQ"/>
    <dbReference type="OrthoDB" id="2341546at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="15"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="660"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO16355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="753" mass="82784" checksum="9A7D6D531496559A" modified="2023-09-13" version="1">MAGSWASGTAFEASHGVGIISPQQTSPTRATPTDDSGARKRKRSSIVTAGENVDGSEVGGAAGGDSGSPTLSQSNGNKQRHQPGVKRACNDCRQQKLRCNVVAGPGGTYKPCDRCVKHNLKCSIDNDFKRLGKRAQHEEMAKELDAAKAKLARYEAMGIHLPEETPRPDSNYTGSYQASPVAGAPVAPMGAGGSTFLGASEAAASRSLLDLSQGYREVAPTSYPSITPGTSIMTLGAVTLSETQLNELYRIYFAHYHPFLPVLNPSLTYKHYYDEHVLLHWTIVAMAARRFESKLGLFMELQRPLEELLWTTLSQVPQSHHVVKALALLCTWPLPTSSTSQEPTMMLCGTMFQLAMQYGLHRPSHAQDFSRFRVDLREEDIADRLNTWAAVNVVAQNVATGNGQPPLSRWAWFTYGLHLDRMKPELQTRCQVEKFCDTVTRTLYTMQRDHIVEVDQAQRGLQIDMYSRELGELEVTVLSTSNSPLEVLFLKAAALHLRLTAFFDKPNQANYHADLRSVYIAASAMLSHLNNMPSDHFSYVPRYIEQMMLAAAVTLLKILNSFYANHVDTVQGCTLFARTVTNLRKLSVRSNDLPQRLAEVMAQLWQTSGASEQKMVFKVDNEPSVLDTENLQLKVRCRSSLSVLYDAIWRWRERAGQAGRDSLAQAVDNPTTLPGDTHTRNTPQPPNGMIDGMPAISNGLDLHNGGLNLADWDSPFGGNAVFDPLSWALDGNLGLGQGLFGGQDTLGLGAYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGG7</accession>
    <name>A0A9Q8LGG7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761368.1">
        <property type="nucleotide sequence ID" value="XM_047903997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGG7"/>
    <dbReference type="GeneID" id="71984727"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04849"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="382" mass="42499" checksum="1D5BF7AA0CAD22C9" modified="2023-09-13" version="1">MLNLLQKHRTVAGSADAVPQDLIALRDNYRSKHMDEVEALRAKAKAVAKKAEDEFNAAAMKAQDAATEAAAKEAEDEKAKAKASEEQAGTTKDTRKNPFDGMSAENRKARDDKDLQVRNLAMAGVGKLVRPGNTQQDMNDTTEKYEMLASSKNGPYIRRPRTDARAAAPAKFTPKRRDDLGNEVVHRTAIDWVKFKQSFEAWLKEPGNVNVQAAIREVLESLGIMVECGSCRAYGRKCDRMIWPFGCGHCRALNQARACTLKLDFNRLCSKGSSKCDGLHTDVAILFLGIAQRLQLKIGPYSGFEVPYNHGAIMVDYTIPDIVAEHDKLILSFEKFTHCVQPIPDGCTHGAQLPKRGLMLKFRHQFSTDGKDQEKLFAHTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGV7</accession>
    <name>A0A9Q8LGV7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thiamine pathway transporter THI73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761621.1">
        <property type="nucleotide sequence ID" value="XM_047904854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGV7"/>
    <dbReference type="GeneID" id="71985584"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05706"/>
    <dbReference type="OMA" id="IVRFQLW"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="61"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="518" mass="57931" checksum="57547F632E366997" modified="2023-09-13" version="1">MAKFGEKNEKNNDVPPEHIERVPTPENGGLDTAFAFLRDHDAIDTHHICLKALRRKLDWNLVPLMFCIHLTQALDSYLLNYAIVMGLPEDLGLEGQQLSNIASSIKWVHLAACAVVGLFLNKFPISTSLGWAMMTWGVLNACTAAVQKYPQMLAIRILMGVFDSMFHPVMMLVTSQFYRKDEQIVRFQLWWCSQGFGTIIGALISYGFQFVNGGGMESWRIMYLVLGCWTLIISIWTLWCLPNSPMAAKFLSTEEKVALLRHIAPNQTGVNNHKIRPKQILDIFRDPQVGLLCSLVIITGFGVGIMSNFSSTLIKSFGYSSKEATLLSAPGGAVAILVCFLSTWVVRREYLRRWSALGICYTIAFVGSCLVAFSPKNNEAAHLVGLYLFDFSTATVGIKFQWNAANIAGHTKRPMTMAFLGASFTIGMIAGPYAVQKKDAPDYFTAKYSLVGSKGGCMVLVCMLALYYLLANRSKDRKFGKQRDLVTDLNDSRSEEESLEGKWANLTDKERPTFRYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH68</accession>
    <name>A0A9Q8LH68_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06313</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761703.1">
        <property type="nucleotide sequence ID" value="XM_047905461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH68"/>
    <dbReference type="GeneID" id="71986191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06313"/>
    <dbReference type="OMA" id="PVPCIYL"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="591"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="848"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="810"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="810"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="982" mass="109260" checksum="FF9F3F7A7B6ABC62" modified="2023-09-13" version="1">MSDPHSHELPGSLNGTALLDHLPVPCIYLTTDHRIAYYNTAARDVIRAKGSIEQHGTSSSYTSIARSILETEFVDIQVKSKHELEQGLNDVATAFGDAMLTTGDQNQSRLNGAEGQAHSISLQSGPTSNWQWTLSSCVIDTLPFLCLTGSVPTPPPSWKTTELTRNEEHELFHSLADPSWRDVPYATSLMYADSNTFQVNEHGRGSLGELARAMTDGDEPSEQHLNVWDEAFNDRKALSDAAGPTTLKSRKGILSLKYGLEDPTTGARSIIDSTCTLLNNPFNDKPLGVIIQAREPQEWAKYIEQNDILSRSYWTTAGARPIMVRTMKSNGIIDYFSDSWEAFAGHTRSRLCQGYWKECIHPDDLPKLQAAVSSSIRYVHVSDCKIRIRHREGGAYRYFTDRIVPFRDFGDHSNRQRWYVITTDIHDLLMRQKLAQRSTERLYNLVNNMPVNMFTLDEDLCIRSSQGALKLDSKGGRLYESVDYEGRGLHEVVGELANTNGINEVVAELEKVAARELDFMITEHQVGGKYLRTFAVPEADEEDLLGAGRKARRGVLALTMDLTAEVSNEKAIHKIKIMQEAERMKDQFLANMSHELRTPIAGLLGMTDLLIETELSPKQSDYVHTFQSSARSLLTIVNNILDFSKAQADAIVLERLSFDFPRLLHDICNTNENLAMKKGLSFHLETPSEPLTLLGDPGRIRQILQNMITNAIKFTSTGYVKLSASYEQHDGIVKVIAVVEDTGIGIDDETLKRLFKPFVQADQSTTRVYGGSGLGLSIARKLAQAMDGDVVLESQKGRGTKAHIILQLEGPQQSTSRESLAGSCSTSNRSNKSQDDQAHVSNLLEDAHILLVEDNLVNKKVVLAHLEKLGVRHLDWVGNGADAVEYVDAAMKQDGGPRSRVRPDLILMDCQMPVLDGYDATRRLRTELKYEGPIVALTASAIEGDRKKCLDAGMDDHLIKPMSRKQLSQTIQKWLSSSRPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI9</accession>
    <name>A0A9Q8LHI9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761912.1">
        <property type="nucleotide sequence ID" value="XM_047905687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHI9"/>
    <dbReference type="GeneID" id="71986417"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06539"/>
    <dbReference type="OMA" id="HANMLLV"/>
    <dbReference type="OrthoDB" id="6357136at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032063">
        <property type="entry name" value="MavL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16062">
        <property type="entry name" value="MavL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="411" mass="45667" checksum="9562F45EC9270AB7" modified="2023-09-13" version="1">MSQSNDGPRLTLDRLFVRPPIKTNSIRNFPPKIIKSDAAATRIIVHPNFPTLASNFLKHELQHGSSHEQSLYKDLTWRTLTSRLIEKRPLAFLGRSDQCTTLRDGRRLNNGKQQWDRNGTEEQHLNEVLMLKNYLSYDEIMLGSLIGVSGPSYFINSGSRNHCGRPDQEPFFEQRGVIMGLVGARFERDDRMDCVFILPPVEEPRMHPELTEIFVNFSEGKRDEAKEFDEVMYSARIRITAEVLLLEANARAAEQGTKAYVYVVGLGLGVWQHSSAQNDLYVRTCAAAISALPLPSIATIEFGWVSCSPASQSAAIKAGNPKGIELLFSRRDPASKRAGRYQDHLLVLSYAWDGNAFPGNEYWQGSLAGSGDPAAACMSTIGELHNPMVNEGLLGRACVVGEGQREDGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ9</accession>
    <name>A0A9Q8LHQ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Transposon Tf2-9 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_05987</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5599418at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="12" id="KW-0229">DNA integration</keyword>
    <keyword evidence="16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="20">
        <location>
            <begin position="228"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="21">
        <location>
            <begin position="853"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="19">
        <location>
            <begin position="1172"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="678"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1139"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1293"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="620"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="678"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="710"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1293"/>
            <end position="1313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO17379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1320" mass="150451" checksum="13FAEA584F3A3F12" modified="2023-09-13" version="1">MDTGALGESFMDYKLATSLNLEPQELKYPRTLELFDGTETTTGKITHVVHTSITLGGKRMSITSFLTSLPHQKFILGLPWFRRHRPIIDWTSLTVSFPPEVPPAPPPSPPPQRGPEYTKIFQVNAAAFTTAAKQPKAQVFAASLRDIDIALEKLDKKRTPTDPATKVPPWAHHILHVFDAKAADELPPHRPHDHKIELEEGAETPFGPLYSMSREELIVLKRYLEENLKKGFIRASRSSAGSPVMFVKKPGGGLRFCVDYRGLNAVTKKNRYPIPLIQETLERLSKAKYFTKLDVIAAFNKLRMAEGHEYLTAFRTRYGLFESLVMPFGVCNGPSTFQNFINDILQEFLDQFCTAYIDDILVYSETKEEHREHVCKVLQKLADAGLQLDIDKCEFEKTEVKFLGLIITADGIKMDQEKIDAIVEWDAPTNVKEVQGFLGFANFYRRFIHAFSGVVRPLTKLTRKGEKFAWTDECQEAFDLLKAKFVENPLLQHFDFELETRVETDASDGVVGGVLLQRRSPESPWLPVAFLSKKLTATECNYEIYDKELLAIVKAFEEWRPELEGSAMPVQVSSDHKNLVYFMKSKLLNRRQARWSEFLSRFNFVISYTPGKANSMADALTRRPGDSPVDRRGGRQIAGQQVIKEHNLSSELREYLSNGQPTLAASFATLVLAPAYLDESDDESEPEEYASDAEDLNDDEEGSVTTDGSSESDFEGFDNEEQPEGIMARVRTAYDADIDAQELVQALRSGARTFPGFSLSECELQEGVVYFRKKLYVPQPEGSNIRAEILQIIHDSASGGHPGVAKTHKLLARYYWWPHSWKDVRRYVLNCATCRRAKANRHRPHGLLHPLPAPDRPWKHITMDFITDLPHGKTFSGVKAKALLVIVDRHSKDRYMIPCWSMTAKETARLFYEFVWRFQGLPDSITSDRGTQFISHFWKRLCAILGIKHNLSTSFQPQTDGQTEITNAILEQVLRCFVDYHQKDWPQHIPAVEFATRNWDSETTGYSPFYTTRGYHPRTGMEPEEPLPPTEDANEQAADEFATMLSQIHEEVHDEMVYAQAIYEDQANRRRQPAPDYQVGDMVYLNSKNIKTDRPSKKLNWKNLGPFEITERISSHAYRLALPANIKIHDVFHPVRLRPSAEDPFPNQNQDMPGPPDEVEVDEPVNLPSDDYAVRKIRGIRVEPNDVEGLPPIKYEVEWQGCPEWDTSWEPIQHIIFNRQAIEEYHARADGPEVNIGRLFESELFDGAYQWCIDHDIRPRPGTEAEHPRYVELLRLRRNSALFGGATVMVSPQSVQKVGTEEPQSAQKSSRSDSPAWRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHU4</accession>
    <name>A0A9Q8LHU4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar cation/proton exchanger 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762062.1">
        <property type="nucleotide sequence ID" value="XM_047905164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHU4"/>
    <dbReference type="GeneID" id="71985894"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06016"/>
    <dbReference type="OMA" id="QVGPHSY"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF14">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="92"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="311"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="490" mass="53554" checksum="E2F30E713CF1519E" modified="2023-09-13" version="1">MTFANQHGTNSSHHGETSPLLPSSNGHENGHSPHTFADGIAHEGESGRSGFHIRHFLHCVWRSSSNVSKAVNILWPFVIIAIVLNYATEAPLWIFAMSYIGMVPAANLLGFAGQEFARKMPKVAGILIETTFGSVVEIILFVVLIVKHKTSDEAEGGNGDEGNLIPIIQAAILGSILTNLLLCLGICFFVGGIRQHTKNQEFHGVISEVGSGLLLVAAFGLLIPSAFYSALKSETVAALQEHFTKSKLQEDILSISRSTAVVLIVAYGLYLLYSCLSAHSIFDEVIEQDEHRDADREQDEKKMKLTLTETFVALVISIIFVAWLLIILVEQLEEVVESGVPDQFLGLILLPLVEKAAEHLTAIDEAWDGVINVALYHCIGPSIQTALFNAPLVVLIAWALGKPLDLNFEIFMIALLVLSILVVGNFLRDQESNWLEGALLVIVYVIIAIASFYYPDPDVATSNGLEELVTQNVTIPAELYKQLLDLLPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI35</accession>
    <name>A0A9Q8LI35_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762151.1">
        <property type="nucleotide sequence ID" value="XM_047905488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI35"/>
    <dbReference type="GeneID" id="71986218"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06340"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="67" mass="7512" checksum="7C66B464BFD2638B" modified="2023-09-13" version="1">MVVQEMATTIKAVDISRVRATTVAPSQAGEASHWSGRDDNWPDLQDRYHNHKIDITRSSTASRMDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJF6</accession>
    <name>A0A9Q8LJF6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_06604</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762089.1">
        <property type="nucleotide sequence ID" value="XM_047905752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJF6"/>
    <dbReference type="GeneID" id="71986482"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06604"/>
    <dbReference type="OMA" id="HSTIDFI"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="199"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="442"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO17723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="632" mass="69656" checksum="2867904444A91395" modified="2023-09-13" version="1">MLRVASSKCPHWDASPLAKAFGLQWRPTRTAATMHKRRPSRMELSGRVAQGPRKTDDGGKPVARRTKNSPFGGMNTTEVPRALQFQKNKISAAERKRQTRMKPGKDREVDRKDPMKALKMQSRLANVSYERRTKVKQEILDLDSFDDFDLLPTIKQSISAQALGGLLDVSPTPIQRLAIPTLLGTEHGRRRKTKAKVVAEVNKSMEPFLLAAETGSGKTLAYVLPVIDAIKRAEAEGAKQAELEKAREAEDDRKYGRTFELQTPELNKVNPAAGRPRAIILLPTSELVSQVGAVIKSLSHTVKFRTAMISAASSGTVIRNRLFSPGGVDVVISTPHLLSSITESDPNILSRVSHLVIDEADSLLDRSFSPITSALLDRAAPSLQQLVFCSATIPRSMDSYLNKRYPETKRLATPNLHAIPRRVQLSVVDVEKVPYQGNRDLACAQTIWDIGKEAAEAGDAPEKKIVVFVNEREKTTELTNYLKSKGIDAVALSRDSDERKQAETLASFTGAPTSPSKQPDKPEKPHSTEPTIAFSPGEFAELSASTAPAIRRLPNTKVLVMTDIGSRGIDTLLVKHVILYDVPHTSIDFIHRLGRVGRMGRRGRGIVLVGKHDRKDIVKEVREGMFKGQALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LKQ3</accession>
    <name>A0A9Q8LKQ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07466</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762914.1">
        <property type="nucleotide sequence ID" value="XM_047906614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LKQ3"/>
    <dbReference type="GeneID" id="71987344"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07466"/>
    <dbReference type="OMA" id="PLMIYRE"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000034">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="267"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="39025" checksum="00510792287E1281" modified="2023-09-13" version="1">MGGKPAVAFLGPKASYTHQATVSQFSESKYNLQPQISIEDVFSAVQTGTASHGVVPFENSSNGSVVFTLDLFADLNGRYPDILVEGEIYIPVRHCLLGHFPRKTRTASESSQERRRTDLPWRKLQTQDSPNASGNVTPTQAVPQPGMPRVKPGCDLKHVRKLYSHPQAWGQCKLFLSTYLKGVERQDVSSTSKAAEFVAQDSTGTSAAISSKIAAEMNGLDVLAEGIEDNEGNSTRFFILRRTSSTPPTPTASLDEKTEMEQYKSLISFTISHEAPGALADSLAVFKRHDLNLTSINTRPSGELPWHYIFFVELKGKKRDGGEDGAVNRALGDLGRVATNWRWLGSWENQLRVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3E1</accession>
    <name>A0A9Q8P3E1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756291.1">
        <property type="nucleotide sequence ID" value="XM_047901316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3E1"/>
    <dbReference type="GeneID" id="71982046"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02168"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
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        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="106" mass="11497" checksum="6F4BD2F8AC519D46" modified="2023-09-13" version="1">MSTSAPVSADDLCLAGNELHKARKVDEAIILYQQACDAAPLDASPWSNLSAAQYELGDYAASMEAGDKALELLEDDVKKHKIMPRKAKSLEKNDLLEASWCQPSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P415</accession>
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        <submittedName>
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        <name evidence="3" type="ORF">CLAFUR5_00305</name>
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    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
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        <property type="term" value="F:protein dimerization activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:SREBP signaling pathway"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019006">
        <property type="entry name" value="Sre1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <begin position="1"/>
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    </feature>
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        </location>
    </feature>
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            <end position="413"/>
        </location>
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            <begin position="953"/>
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        </location>
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        </location>
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        </location>
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        </source>
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        </source>
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        </source>
    </evidence>
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    <sequence length="985" mass="106329" checksum="A2ED3AB3D37D0D78" modified="2023-09-13" version="1">MDNSWQGGFSQQQLSAFNSQLDAGQSNEDWEAWLRWDPAGEASSPGDGTFNSASSKNDSPLQDPLFASFHQTNDEPLNPPLIVGDDDLAFGAGNGMANEPFLFGDIGDIGNGFIFDQSTDIHNIQSIPKLDTNTAAWPLLSHDGPDTSLDLSALIDDQPQQPISALTATTPSLHHSPESTSRQRTSIASTTSPAPVPAPAKKKGGRKRKAETQLQPQPETSPQNAEGGSGEEEGEDGPIKKTSHNVIEKRYRNNLNDKIVELRNAVPALRAVGRNGEEVENLEGLTPAHKLNKATVMAKATEYIRHLEKRNKTMSDEMDILKAQLAKVEATIGKTKDRQASFSMSSASSPTSSSSRSREASSASQAGTPSFLNVPQDQQSRFGQAVVQQQYMQQQSQPSYARAPNPPVDAQNQPHVVKRRGGFMNKVMLGTMAGVMAMEGFTEHQASSDRSMAALPTALFKRGTGASPSLAAGLSRQAMIPLLKMLLVVGALVYLLTPLLTFSSRRKQKMRAATQLPKAPSLASPVEVRRKAWDTAIQSVWVPKHFLVEVVAVGLKMLSLSVRRLIGSEAFTNITGTSKEEEAARIKAWDIAIDAQLAGGDARVSYYRLLLTLMESGTLPDSPARLAQKAVHFRVFFWEVANAGYGNMIGFKQFTEKVGKYYWDSARRLQKELVHAKLQGRPGDEDEVETLPDHLAQLVKLDCDEVLSDEMIQRAWNLAWNKPSAHALVPNAARDSVVEDHAIRSPLDAVAAWYTNTVIDDTLADALSDTNSTIDTEYHVGLALSVAPPASSTHVRALTAKAVLSNTKREANIIVALEALPVISPTGGMNLVNHAPASPDVCTALTLAKLISLSSPQSSQAARERAYTALRGVQPAPGEFTPLTVIATYRLLRSLSGRKDLSRNAERGLEELAGNLRVWVGTSGGRDSGLGNEGRTKLVKLCLHIAKQLGGWDEGDERDSGYGSAVQSQSSSPARAVASPSMVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P445</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P445"/>
    <dbReference type="GeneID" id="71980198"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00320"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="114" mass="11864" checksum="0537C09A26E36077" modified="2023-09-13" version="1">MLCIDMLMSMPSMEHIAGPVSAVIPGAVEVAMFMRDVVLVPFAMAISVIVEEAMLMPNMSMLNGPLLLVDPGAMGGPPGLDACSNEISKACGLSKTIETHGHSASTNLPPTPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4T5</accession>
    <name>A0A9Q8P4T5_PASFU</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
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    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8P4T5"/>
    <dbReference type="GeneID" id="71982417"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="339" mass="38887" checksum="EE4964864555C2E8" modified="2023-09-13" version="1">MSLSTIYHRLLSFFHTRGSRSKRQDITIQPVGQRSKDLEQEVTPLTQAEPAMEGPGNAADSSTTQNSFTKFFELPYELRDAIYEYLLPPNSKIHYIGGPLPSGTFHIEDTWISNMCQADPRFNPDLERIEQVRPICRFIVSPDGCDIPHDFDINKYKRLEIFFEHYHLATPGVRGHHIAFSHSLMTMSNNFRRFVNRIKTHERLPEIHVSFRDEPRLGLYGDRHWTHELQQGGQFTQVPAQILSISRGERMSLIWYLLEPILRLPLAKTATIQPITCLIASGHNGPFDSFPNIENLSGRWMVALCSALSSWLEGEREQPFEDLLNQRSSGPGRLALAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5K5</accession>
    <name>A0A9Q8P5K5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02500</name>
    </gene>
    <organism evidence="4 5">
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            <taxon>Fulvia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758390.1">
        <property type="nucleotide sequence ID" value="XM_047901648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5K5"/>
    <dbReference type="GeneID" id="71982378"/>
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    <dbReference type="OMA" id="CYELAMQ"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
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        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF33">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
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    </dbReference>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="442" mass="47192" checksum="2EB7460B1E5A0345" modified="2023-09-13" version="1">MSEVYSPVDSQAGDEPGAPVLTRRATIGDPVYDNQVQVRQRRKASVVACDRCRKRKIRCDGHQPCATCARFNVRCARPEAGRERSSSSAEHSALADRVRMLEATLAAVTSNNAAQSFFEGSEMLGEASSRPTLQIDTSFDDSSLSRSFSFNDLNAPETDDSSSLMVPSIQITAPHGSIPSSPLAISPSSLYTGTTRASTPDPMSAMSMTFDSLGTGMLAPSSTGHARTPAVSQWAEVYDRGNTLQTPGSTHGSGWISRRSSISSFGGLDQGICDMNIDMPPMSPQTGDWNFQDPFDHSSMLGHNGLAAEHRMPPIAQAEALSQRAFGHGDMPIDQTAFKVCLGAAYDAANHSNTMSSSNMPSAAQLMLLTLTPFSLRMARCLAFLVLTIGSKVDISVGGGNIVLEDCYAIAQEQMRTTDFWAEPGAQKAASLLGILSSISMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7A2</accession>
    <name>A0A9Q8P7A2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760204.1">
        <property type="nucleotide sequence ID" value="XM_047904074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7A2"/>
    <dbReference type="GeneID" id="71984804"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04926"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="556" mass="62020" checksum="9555A2FF018249EB" modified="2023-09-13" version="1">MNDSDQPPESRADQGPSASRYKNPCDAERSSDSRLQPDAPHADQELVQSDGSISEPPSQQAQPARNEGPQEVHQDGSRYFISGKHSERSLLLLEQLQKTHPVTGRSKIALKKRRNRIQAELDHFEYLMDMTSPQGPPQMRSSARPPQVLGNQPLGHRSTNITPSSNNRQSRQSTIVSASQQYQQDQNGGHSTTQDVDIREENEKFARGMKRLRSTPMCSSSWQYKENASRFHAMQEDLRARAALRRSRLDHGHRTDLSLQEANVEISPARGSTNRAPDAYGDSSVHGYQAPSFEYQAHAGRTIISTFNATDVLSQHNGCSTERESVVLKRWRHADSAKAHAWPLAFANDGPAIIHYVAPPVAGLPRLRAPEYTNHPQQRRLARHNQNPMMQSPHFRGAGPIARARVSGTAHSPTIGTGPRALNSYQPPPPAPSGALCVALPSGPRHAEESVNSRIAFAISTPVQSTTKQDNRTLSESAFPWPQVNTNQQSQQRHKDAAGRIFEKFQNHGVAEEKSPVRHVQIDEKKLKRALAEAREEQARKKQKREYQERAAAERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7K5</accession>
    <name>A0A9Q8P7K5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760580.1">
        <property type="nucleotide sequence ID" value="XM_047904414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7K5"/>
    <dbReference type="GeneID" id="71985144"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05266"/>
    <dbReference type="OrthoDB" id="3650962at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="657"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="677"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="809" mass="90788" checksum="3D48F21B7964EF04" modified="2023-09-13" version="1">MCAVRDGATSTSGESSGLFVTPTSSSHEDEGPTTQPPALNAVNFDDDDELYRCTPDPNRRATSRSSAAILRETYLAARRRRITSQTPSPQSQQSRSITGRRGPFREDSSSSVPSASRPSTKHSGNEHEAHGESTTQENLVIPLTSRHNPFYSSSHQEQNVPTTRRTKHHHPRRQSSAETNPIRSPTSLVRPGNGHNSSQDPPRRHLPLRQNSRPASPSRARSETGSSFPGFVQEVSDRTPELEDTEMVDATASQTEERREIPSSSPLSSLRSTPEIQERDWEIVRLEATRVKDCVRERKIAWRGTRHSSAIMRMRPGGEVVLNVAGVRWGGMREQTVEPGEVDNDGMVRVYWATTWHPDWDLPKSLVAGWEREYGEDEVSKEDKQQPRWWLWPEQTEDCLPSEPEPDPGERELMPLTDDETFTLEPGKDYTISFLEERRAALSLPEPDHAIPESTIIRFLNMHVRNRLRVVDSFEEHAFRSNTLFVRTSLIYIFGTAMIRPCSHCRDGGGPYPRCVIWLNELGGACCNCAFSRRGVGCEYHFAVRWFKASALAADGDAVMVDEDSDPSPPSDYPSIDPSNEPTSTPPSSDPDNVESRDAQHSGQIISVRHDMPDFGHDGDPDKEQRQRSSSPAGRQHHQHTQARPIGKLKASDGPSRKTTPSRTRSDSTTSIKSEQFESSPSGSSTFHHPGCPAPPAPCRDPICGQNISSNPTHHTPVFRGDSFRKGQATDDQVNFILSCCTCTNTQALQQAWEEFRGREERNGVSQSLSRYESRERYFSSDCWRVLNQLVGWCPEKWRFEGEIDLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA23</accession>
    <name>A0A9Q8PA23_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oxidoreductase ptaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_07414</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763015.1">
        <property type="nucleotide sequence ID" value="XM_047906562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA23"/>
    <dbReference type="GeneID" id="71987292"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07414"/>
    <dbReference type="OMA" id="DHSKMAM"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040319800" evidence="6">
        <location>
            <begin position="20"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="164"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="288"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="511"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="685" mass="74384" checksum="D9E150D0693822EB" modified="2023-09-13" version="1">MLPMLRLAASVLLLNTVSASPWLVARTNSSSSGGVSSSEGQWQHGGPPSSHSAIVNTTGNEPASSEQAQLLSVPVVPYGGSGGSAYHGPAWISSGHGLHPSLSQSQTNGGCELGTLNASKLPDFVHSGPMPGGKPWGDRTCKDTNQLDDTPNTGMTRHYDFTVSNMVIAPDGVEKNAVVINGQFPGPTIEANWGDWVEVVVHNHLEEGTAIHWHGLLQKDTPWMDGVPGVQQCPIAPGSTFTYRFRADLYGSTWYHSHYSAQYAGGAFGPLVIYGPHDNAEYDEDLGPVLIHDWFHKDWFSLVEQVMAPETEKLPPPPSNNVLINGKMNYPCSNATGYKCTPNAGVSKFNFESGKTYRLRVINSGAEAMMKFSIDGHEMSVIENDFVPIVPYTTDVLTLAVGQRSDILVKATGKPTDAVWMRADMGPSFFKGGCSIHDGVSPLGVAAIYYEDADTTAAPTTNSTVPESALTSCQNDPLSSTVPYYSLTPPANPETVQNVDITFQSNGTNKLFYMNNSTFRVNFNDPVLLKAKLGHSDYPASYNVYNFGQSKSIRMIVFNHAPTGAHPMHMHGHNMYILAEGYGSWDGTVVNPNNPQRRDVQVLPNSKSPDNPAYIVVQFDADNPGVWPFHCHIAWHVSGGLYLNILERPDDIQKDMAIPGVMAQTCRDWSTWTGQNVVKEIDSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA62</accession>
    <name>A0A9Q8PA62_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-methyltransferase ustE</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_06923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA62"/>
    <dbReference type="GeneID" id="71986801"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06923"/>
    <dbReference type="OMA" id="ATHINYG"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="264" mass="29277" checksum="38D5EDB289B606FD" modified="2023-09-13" version="1">MPPHPSPRSNDPIQRGLTSPSPIETTTFFLGRLASPVLQYGILKRSWGAPLLHRLHGTTLPSGPPWITATPLDRLGLSPYRTILWAMSVGSVAKQNYHLLATMQEKLKPGFGAQVAVFNAVADTINSMLFVCAQTSASVNGEGFPQTPLIVGGALYVTGILVELVSEQQRHNWKRRDGNRGRVYGGGLFGLARHINYFGYTLWRMGYALAAGGWTWAGVLAALSCWQFTQVTIPAHREYLEGKYGEQYRAYEEATPYRFIPYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAQ1</accession>
    <name>A0A9Q8PAQ1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAQ1"/>
    <dbReference type="GeneID" id="71987611"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07733"/>
    <dbReference type="OrthoDB" id="2212170at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF43">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="20"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="168" mass="18364" checksum="AE96D22F938C81DF" modified="2023-09-13" version="1">MAPDNSAALGTDVDHGVDSMTGSCLCGGITVTVRQQGLFEKPAGHTCHCANCRKMSSSAFMSLLMIRTSDLDMSDPKSLLRIYGDNNSTSGRTVLRPFCSECGSPTAATSESEPRLSFVALGLFPKTPKPEFELFTAHRQDWAKPLTTAETQYLFADEVLQYKDRMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAS3</accession>
    <name>A0A9Q8PAS3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763371.1">
        <property type="nucleotide sequence ID" value="XM_047905808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAS3"/>
    <dbReference type="GeneID" id="71986538"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06660"/>
    <dbReference type="OrthoDB" id="346673at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="7">
        <location>
            <begin position="230"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="8">
        <location>
            <begin position="512"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="578" mass="64303" checksum="9B270FBA6BBEB8AD" modified="2023-09-13" version="1">MPKRRKADDEVEDDGPTPRKSVRRSARTAAEESQSPAETASRRKGILKHATPSKANGLKSVEATPSAMRKVLFATPKADKEDINGDDEDTPIAARNDRSARRKRGRILQQQIVEVDDSDGEADERDAAVAQAILGGEDEEEDEDEIELNPSSAPDTPSKTGRPRGRPKGKRRERTPSPPPNLPSHELYFLQNKAGANKTSANTLPSQLLLSHEDYFAQIAAYKDPHTADIERLKQLHKPAFDQWVFELEEGFNICLYGYGSKRKLLLDFATHVYHQSTEAPKMIIVNGYTPNLTIRDILTTVAGATLPKNTKLPAQPQALLELLLAEMTSPITIMIHSLDRSNLRKSSTQSILASLAAHPHISLVATCDTPNFPLLWPTALTTQFRFLFHDATTFEPYTAELEVVEDVNALLGRSSRRLGGKDGVGYVLKSLPENARRLFAILVAEQMALADTELDAGGAAALDSDNDDDILRAEDEEEAAAETPSRKPRRGRPAKKNKTVEKTAKKQQVVVTGVEYRTLYHKAVEEFVCSSEVNFRTLLKEFHDHQMIESRKDPMGTERLVVPFRREELEAILEELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBI5</accession>
    <name>A0A9Q8PBI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General alpha-glucoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO19432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBI5"/>
    <dbReference type="GeneID" id="71986576"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06698"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
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        <location>
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            <end position="182"/>
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        </location>
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        <location>
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            <end position="300"/>
        </location>
    </feature>
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            <end position="391"/>
        </location>
    </feature>
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            <begin position="429"/>
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        </location>
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            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
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            <end position="650"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="696" mass="76245" checksum="6AA677C3541E4587" modified="2023-09-13" version="1">MDLPDSSPGSSPSRRGSHLDTATNGVPSHPKHVSWRRESRPSFTRDEPRRNSRQMSTGNAHIRRSVDFVKAEEEFNESSPLLLPRKSEEVEALPPLAEVFSPDESSGESSWDVDMGTKEESKSTVYMILLTISFLGLQIAWSVEMSNGSPYLLSLGVSKSMLALVWIAGPLSGTLVQPYVGIKSDNLQSRWGKRRPFIVGGAIATIISLIILAWTREIVGGLLSIFGVSRDSSGTATCSVVLAVLMIYVLDFSINVIQAAIRAFLVDSAPTHQQDTANAWASRLSGIGNITGYLFGYANLPKYLWFFGDTQFKVLCVIACLVLAITVAISVTSVGERDPRQDGKPMQQTGGVIAFFRQLYRSVKKLPPQIKAVCVVQLAAWIGWFPFLFYITTYIGELYVEPIFKEKGPDLTDKDIDEAWEHGTRVGTFALLIYAIVSFLASVTIPWFVASSYDPENLHDTPRTPGTPMARTPGTPMTDLTPGRFGDGGDGYFGIRASGAADARSTKSTFAQKAKKWFTKKRGRSLAIPWLTLKRGWLLSHIMFAILMWLTFIAKNTTVATILAGLVGIPWAMTMWAPFALIAAEISKRENIRRGIIKPPPTRDGELLARGEDTSEGADQAGVVLGIHNVAIAAPQVIATLISSAVFKALQKPRGSVGDDSVAWVLRFGGILALVAAWLTRRIKEEDDPEDAKPHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBR1</accession>
    <name>A0A9Q8PBR1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763930.1">
        <property type="nucleotide sequence ID" value="XM_047909065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBR1"/>
    <dbReference type="GeneID" id="71989795"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09917"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="84" mass="9241" checksum="66956B663A4603FE" modified="2023-09-13" version="1">MALQSSESEVIHSKEHFAPYEGTVISPLIVANTHSVMPNMPWRTKKQPKRQDAAAPSVKRKQVSIRTILPALLALFGPVVSPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD63</accession>
    <name>A0A9Q8PD63_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-arabinose 1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764631.1">
        <property type="nucleotide sequence ID" value="XM_047909295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD63"/>
    <dbReference type="GeneID" id="71990025"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10147"/>
    <dbReference type="OMA" id="FPRSSYK"/>
    <dbReference type="OrthoDB" id="5286008at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045290">
        <property type="term" value="F:D-arabinose 1-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070485">
        <property type="term" value="P:dehydro-D-arabinono-1,4-lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19164">
        <property type="entry name" value="AKR_ARA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000037">
        <property type="entry name" value="L-galactose dehydrogenase (L-GalDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044480">
        <property type="entry name" value="Ara2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="49181" checksum="22BC7540E77B9E2F" modified="2023-09-13" version="1">MASDEQKVLLSSVLPPLIFGTATFNYQYNPDPYELDPPGLVKTALEHGIRAFDTSPYYGPSEDILGAALDTDFVHENFPRNDFFLITKCGRIANDEFDYSKEWVRHSVQRSLQRLQTPYLDLVYCHDVEFVTEDEVMEAIRELRRIRDEEGTIKYVGISGYPVPVLCSLATRVLRETGEPLDAVMSYANYTLQNQLLASTGIKQLKEAGVDVVPNASPLGMGLLRRGGVPVGSMGNWHPASNGLRAAVKRASDFCDRHDEKLEVIAIRYALEQWLKIGASVGSRGDPASGIPWKRESNAQVGGDRLGVSVIGVSKAGELEKTMQVWRSILDGLENGAETARLAGRWKRDHEWSLNRQRAVQILADGIQEHLDEYLDYTWASGNDAGTRGAAEGWTPFVNKRAKSKQAAGNGTQSEDAPPPWLTPAQSPQPNHEPDEIPPTLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD93</accession>
    <name>A0A9Q8PD93_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10017</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764677.1">
        <property type="nucleotide sequence ID" value="XM_047909165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD93"/>
    <dbReference type="GeneID" id="71989895"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10017"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000409">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000076">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="108"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="316"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO20311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="616" mass="68084" checksum="7D84FFF176AB3869" modified="2023-09-13" version="1">MNSGSESLKKAAVNKAKQLAHNGTSNKKRKQLNPIITTESQQGGGNPYNGNNSAQAHPQYGQDLHDSPSDSESDEAMSQTQDEEDSEDYCKGGYHPVSVGEQYKDGKYTIVRKLGWGHFSTVWLSKDNTTGKHVALKVVRSAAHYTETALDEIKLLNKVVEANKDHPGRQHVVSLLDSFNHKGPHGMHVCMVFEVLGENLLGLIKRWNHRGIPMPLVKQITKQVLLGLDYLHRECGIIHTDLKPENVLIEIGDVEQIVKTYVKEDAKEKDDHRNGRRRRRTLITGSQPLPSPLNASFSHSDLADFPGSTQSLNAVVSDRKGNSDSPIKGASPTGDAGAEMSGAIGSTSQTQPKSMLEQLGLKGEMSAEPGSTEKDPHKEREKTARSDILANNVSDMDLGNSHAVKPKVVEKAEKEDGIDIISVKIADLGNACWVGHHFTNDIQTRQYRSPEVILGAKWGASTDVWSMACMVFELITGDYLFDPQSGTKYGKDDDHIAQIIELLGTFPKSLCIAGKWSQEIFNRKGELRNIHRLRHWALPDVLREKYHFSVEEAKRIGDFLLPMLELQPAERANAGGMANHPFLDHTKGMDPVKLDIQVGSKGEGIDGWSTEVKKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDB8</accession>
    <name>A0A9Q8PDB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764740.1">
        <property type="nucleotide sequence ID" value="XM_047909427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDB8"/>
    <dbReference type="GeneID" id="71990157"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10279"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="120" mass="13803" checksum="DC8DA3722E555409" modified="2023-09-13" version="1">MSEEGVGKRKPPPPPGEKPQLVQNDSRSQVAVRNYEKPSESEKTTGLDKPSDENLIDGSNTSDENAEHYKADDFRWDSYGAYLGGKAFLDFYTRLVKNRWEWFRQAMTYTSRRASNEYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDJ0</accession>
    <name>A0A9Q8PDJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764826.1">
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="22446" checksum="984C84CB4D417B72" modified="2023-09-13" version="1">MSRTRWLLATLLALSSTALSIDNTTMTMTLSPPNTPSCGTQDTTSNEAITFSLTNTPTTPHCFNLNSTFTHPNTTVPNFTYTLTGTSSFDYSLNYSQISYSQPASTSTNLTLKTYNGLDCNQVAESDGLIEPWTEWTCSTPSSGDGECTTLPYSVRSFEIRPVGERERRSGMECVVAAAYGKESAASGRVKVAGWGVVGVAVGVVVVMCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK9</accession>
    <name>A0A9Q8PDK9_PASFU</name>
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    </protein>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellales</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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        </source>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14279" checksum="605EA207EB58D9CE" modified="2023-09-13" version="1">MQANVATMAPVTPAAFCTIEPASKSEQSIEQQPMPEWAASAISYFHQGCLPVTLIALTISIWSLWALSDVFPSGGVWTIIQLAFGLGVFKASEWACNMAFAVYAMFVLMHRGVKKLAASHSKHMHSIGEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDL6</accession>
    <name>A0A9Q8PDL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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        <location>
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            <end position="471"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="471" mass="52412" checksum="94AF35245B113A04" modified="2023-09-13" version="1">MSELLEFLRMHEEAFRSRSRLASLYCDFRYQRSTNPDGYTANSSAWLRALSSAAKAGLIPAPAGQHGTDRFVIQSGEELLRELQTQEFGWPLALGAVLEDAVKRKELIPLREFLDRKDSVYAKSWIPSPLDVVKWGLRQLGMLGDGSSAQDRLVRGEFVVVGNAETAAKAVLEEASRSAVSNTSRVFSKDLFSTTFAKTLCMDTISRNDLDVLLRHLQRDRSAIAYNATSGIIKFKASNEPDPSPINPEDESIASLRTLISSLEPQIDALTTRISSLDLTARTAVSQKQLTTAKTALRQKKLADTRLQQRTSTLAQLEDVYAKIEQAADQVEIVRVMEASGQALKSLNKQTGGVERVQDVMEGLREEMMSVEEIGEAIGEVGVEGVDEGEVEDELEALERVEREKQEAIEKVESEKKETVEEAEREKREAEEAEATRLRLAELDKVGEKTEAEKEPETEHEPRTDAEKITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDT0</accession>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
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        <location>
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            <end position="379"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="39589" checksum="1ADC6EE4E718B6F0" modified="2023-09-13" version="1">MYSQLLVSALVASAAATAVPHNQPQPNKGYSWGDKSPAAPTGANGKNQPFRFPLSNGFPNIQVPSDALTAIQKQAHGTLPNGALPKKINDTSATVLELIAFNEIFEVAYFTSLLGNITDGTFDVGKGAAKDIVVNAITAVQAQEELHALGANAILATAGRTPIKPCEYKFPTTDFDSSISLAATFTDVVLGTLQDALEAFGTDGDSELLALIGSVIGQEGEQVGFYRNIGKKIPSALPFLTRSTAPFAYSALNQVFIVPGSCPNANIIDIPIYEPLTVVTPPTAPEDTTVTFSIAKKAGVDVTKMSIVYINQQNVPVSEPVRSVAEKDGQITFCADFPGEKNLMNGLTIAGLAMGAGPFADVAAATAATKYGPGLIEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">CLAFUR5_10817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        </lineage>
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    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDU4"/>
    <dbReference type="GeneID" id="71990695"/>
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    <dbReference type="OMA" id="VRIMRGD"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15355" checksum="39ECA58513F14F96" modified="2023-09-13" version="1">MTKINTNLSSSRRKSRKAHFSAPSSVRRVIMSAPLSKELREKHNVRALPIRKDDEVIIKRGSNKGREGKVTSVYRLKYVIHIERVAREKSNGQSVPIGIAPSKVEITKIKLDKDRESILERIAKGRDLNKEKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEK8</accession>
    <name>A0A9Q8PEK8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase ntnJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11526</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765385.1">
        <property type="nucleotide sequence ID" value="XM_047910674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEK8"/>
    <dbReference type="GeneID" id="71991404"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11526"/>
    <dbReference type="OMA" id="CRNDELG"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF215">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="48991" checksum="0BDBC823E4EB9B04" modified="2023-09-13" version="1">MGLQVIIVGAGIGGLAAAVALRRAGHRVTVLEKYDSKSEVGFAVGVFPNATRVLRSLEIDFKQIRLSPWVGLNYARADLDPMELVADVGAAEGKVLSTDYGAPSCAAHRVDLHEALRDHAIRPEGTGPPAVIKGGCTVVNYNPQAGSVTLQDGAVLKADVIVAADGVKSKAHIAILGYEQPAKLTRLSNIRFVLPTDKFKEIPELQLMPEAEKMPTFYRGADPSRGLLRYPCRENTLQNFGLYEVSTDLPADEEKWRTQTKKEIALERLKGFNNGLHEVVRRADEKDMYLWKVADRMPLPAWTKDKMTLLGDAAHPMQPTLGNGAAQSIEDAGVLGTLLEGVDDPTEVPERLKLYEELRRPRASAVQLLSMSGNLYYRLSDEVQKVLRTFVAEEDFPVLTRPGANHFLFKFDCIEEARRVLGERYGRRTDSVQGFELYGNGHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEP5</accession>
    <name>A0A9Q8PEP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765445.1">
        <property type="nucleotide sequence ID" value="XM_047909990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEP5"/>
    <dbReference type="GeneID" id="71990720"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10842"/>
    <dbReference type="OMA" id="HYKSINC"/>
    <dbReference type="OrthoDB" id="3650750at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="236" mass="27466" checksum="F6BF30165FE63101" modified="2023-09-13" version="1">MGAMQVIKTGLISRAEIIRNNRERLLEKLPTLPRYFLEYIIKKGETNTYRSYMSVIKYKSADQSLRKRIQALPQELQDIVFDFCIFSRSTNDITYITNLTKPPLGLQINRKTRSKFARQYYGNGSIFEFSATSTGCILLCGKWLASLQSDHAQLLQVVKVQYEYAAIVDYHRSINWSSRNRFQGVVVGLRRQFLALREEILYVNQYYCPSGSRGPLDVEMWYNLRGMIGVEQVSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEY8</accession>
    <name>A0A9Q8PEY8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765591.1">
        <property type="nucleotide sequence ID" value="XM_047910362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEY8"/>
    <dbReference type="GeneID" id="71991092"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11214"/>
    <dbReference type="OrthoDB" id="3907547at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="476" mass="53424" checksum="7A9C6166FA43C723" modified="2023-09-13" version="1">MASEMFKKQKQRIPHKKGREVFANFKAAGWNRDQLAVVKSSKSLTYKHQLVQGAGGSGKTKLMTAKGHEISTTGNEYVLYTTERNSICDNLLDVYVKHYPEDQAPLRAFAQGASLSEMTGKQDSAGEVNPAEVVMYELLKKRQQDRSSARTQRMRFTVEHHIIQAIQDGKIQQVQLTSDEKGEEGKNKPHPDHPDPVNVFKYFNELLEEAKLHPLGEMVALRVDSDATKHSVAKLMDPTHPSNGEAKNGPDGGEAPAAELDKQEVQHDQTAPAVMKLPPLVPEDVSDLKSDAGEGLQLSEAKTGPYRPSDRLRLVGRALKACRKNVIASAKVLIATLATVGSDDIRKYWAPDRSHQVWAEIDEATTIPEVMFYVPHANCYSTWGKRIVSTVQYGDHRQLAHALWHPITQKYYNRRISTLAKAPSFGLDGDDVAMVKKARNWPETTNDDLDEFQQHWLWLEVEGTRWAKDESFTLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF03</accession>
    <name>A0A9Q8PF03_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase FUB4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765563.1">
        <property type="nucleotide sequence ID" value="XM_047909915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF03"/>
    <dbReference type="GeneID" id="71990645"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10767"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF7">
        <property type="entry name" value="SERINE HYDROLASE FSH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="30729" checksum="BA7EE59863EBC241" modified="2023-09-13" version="1">MSKNVKIFNMQTSSIRASLEDFDFTFVQGTVRHTEGNWSLHTTQFSALPLYTYYNPLDPTSIRQTHSELRDIIANEGPFDGVLGYSGGAALAAELLIEQDPFALYPTFRFAVFVNGASPLRVFNLADVEMAEQGFDPTAALDDARSMFLRPSALRHKAGVDEEDQADHAKLLGLLEKLEGKMLRDGTAFLSNGIHGLTRWQRGADGVPLIDIPTVHVRSTADDDNDPHHGLHLLQLCDENKTCEIHHEFGHDFPRGRRLMTQIAEAIRDTAEAATGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFW3</accession>
    <name>A0A9Q8PFW3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitobiosyldiphosphodolichol beta-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.142</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08849</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.142" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766107.1">
        <property type="nucleotide sequence ID" value="XM_047907997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFW3"/>
    <dbReference type="GeneID" id="71988727"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08849"/>
    <dbReference type="OrthoDB" id="614844at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004578">
        <property type="term" value="F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03816">
        <property type="entry name" value="GT33_ALG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000162">
        <property type="entry name" value="Beta-1,4-mannosyltransferase (Alg1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026051">
        <property type="entry name" value="ALG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036">
        <property type="entry name" value="BETA1,4 MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036:SF0">
        <property type="entry name" value="CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="511" mass="56581" checksum="C1E80F8D720AFA50" modified="2023-09-13" version="1">MYGRRQEGSIWPATVAAMTWIALACTAALYGAGVCSVITFLLICTLPSTYSDFPPRALAESTFTDDAKREREKSGYAYYAKHKDSNGRLKVDASVQIVVLGDIGRSPRMQYHALSIAKHGGKVDFIGYMGAQVHPDILKSAFIDIVPLKPFPAALQTSNKLLFLLVAPLKLLYQVFGLYYTLAYRTKASRWMLIQNPPSIPTLAICQAICFLRNTRLVIDWHNFGYSILALRLTAKHPLVRISEWYEGFFSAHGVHAHFCVTNAMSRVLKDKWGIENALPLHDRPAEIYQPLSIEQRAAVLRRLPGTSEHANDILEGRCKLLVSSTSWTPDEDFSILLDALVQYSAAVAADNTLPNIIAIITGKGPQRDHYLRKIEALTREGKLPYVMVATAWLSPEDYAALLGAADLGVSLHTSSSGVDLPMKVVDMFGTGLPVVGWGDFEAWPELVKEGVNGKGFDSADKLASILKDLLGDDGSGLMELEELSRGAMKEVRRRWEDEWMPVAGKLFQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG97</accession>
    <name>A0A9Q8PG97_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766317.1">
        <property type="nucleotide sequence ID" value="XM_047908631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG97"/>
    <dbReference type="GeneID" id="71989361"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09483"/>
    <dbReference type="OrthoDB" id="3650339at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="21343" checksum="61F9FFB3E3A874B9" modified="2023-09-13" version="1">MPSVYAGTIEPWLSQMAPDVLEAMPDVEIILRDLRPYVTGHPIDRDRHLSLVNHSNRLHAAWVPPNAQPGDIVCYFAGAPFPLVLRQRSELESHTLLGDSFVEGFDEVDALDLDDTVWQDLLKQSKDADAELKDWMASSDRTSLKENAGDLSKVTSQDNHLKARRLNILQEMRSLCRTADEALGWIKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGN4</accession>
    <name>A0A9Q8PGN4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766438.1">
        <property type="nucleotide sequence ID" value="XM_047908080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGN4"/>
    <dbReference type="GeneID" id="71988810"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08932"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="23652" checksum="F8DAF4F2E3306D0F" modified="2023-09-13" version="1">MRSLCRLKLGEPAGRVTTTDADLEDGELIIVEDPPTQKPPKTGGKRKYDAGRGDDSATSAPDRQPAPSKKRKTADAQTKKPKPASPKYTKAETTPHARGEKRPGGCPDEIQVMEAYRSSLAASGRGWDPIKNDQMKALLLHYHGITFSANRVNRAPLLAILEPLCKDHCQKQDEADRERRRRNDELKEAARRKDPNYVSRDMVNSLKSAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH94</accession>
    <name>A0A9Q8PH94_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09157</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766765.1">
        <property type="nucleotide sequence ID" value="XM_047908305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH94"/>
    <dbReference type="GeneID" id="71989035"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09157"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004631">
        <property type="term" value="F:phosphomevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005919">
        <property type="entry name" value="Pmev_kin_anim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF25">
        <property type="entry name" value="PHOSPHOMEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04275">
        <property type="entry name" value="P-mevalo_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="315"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1150" mass="124648" checksum="1C21431687F00DBF" modified="2023-09-13" version="1">MNTTLSPKLPATMTATAMATLGELKHALKAAAPSVKRERLSESQYETGFDLLLTGTTVYEDFIHPEVCRQLTDGPRGPISVLEIGPGPRTVLAALPEVLRRNITQYVAFEPNHTYASSLEESLLCREGAASPLPCLDGAATIYKKPFFLGNDHDDVSIEQSHGAFDIILFCHSMYGMSPKRSYIEKALHLLKKSDGAKVIVFHRNESLNFDGLVCQHTASFPKGVVHVPDLDNSLDSFASFVAGEILPLSEEGNFAQQEWRKICRELSQRSQSGGHVFSSPELMVTFTHGSLELEEIVAKVPTVKLDKIKNPEARHRRPASIVKPAGICQVQGCVQWAIKHGLTLAVLGGSHGAHCIVDNVVSVDMSCFDQISIHRSTESPGPDSDTLVIVGSGCKAGDIVHRTMEHGLTVPLGSRPSVGAGLWLQGGIGHLSRYRGLTCDTIVGAVLVSVDDARVVVVGEVPDDHLPQNAVRPENEAEVLWAIRGAGTDFGVVTNVVFKAFPVETFLTTNWKLPLNDEVEAQGKIDAVNKTAATLYTRNSVDMYLYWDGMRLSLGVSLYGAASPGLTFEAMTPTTMCLRSLLGTETKSETCDGIQLFESEMYMSGMHGGHGGGKTSAFKRCVFLRDIGTPEVVNALLTAMQTRSSPLCYLHLLQGGGAIADVKSDATAFGCRDWDYACVITGVWKRDQDGTAAARAAVEWVYRVVGDLLPLSSGIYGADLGRDPRDADLAAHAFGPNRLRLGRLKWKMDPHRVLAHACPLPQKPRGPRLIILVTGSHGAGKDYCAAAWNDELDGDQHIVHVASISDMTKKEYAASVGASYERLLTDCEYKEKHRPALTAFYDRQVAERPNLPEQHFLQVVHEHSDADVLLITGMRDKSPVATFSYLVPYSRVLEARVRTSNHNIAARTGSGIYPNNNSPAPSATTCPPDFIFDNDTQGSEEAKKFASHFLLPLLQTDLTHLADMVRSTPNHPRSGVNFHHILGIAQHPDGLALCTSLLRDLFSTSWPKIDTIACCESGGFIFASALATNLNLPLALIRKAGKLPPPTFSVGKESSYISSLSGTAEGEETFEMEKGAVAKGSEVVVVDDVLSSGKTVWAVLQLLRKAGVRPADVTVMVVAELPGHRGREFLRMSGFGEVSVRSLFVYGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHH4</accession>
    <name>A0A9Q8PHH4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766885.1">
        <property type="nucleotide sequence ID" value="XM_047910972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHH4"/>
    <dbReference type="GeneID" id="71991702"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11824"/>
    <dbReference type="OMA" id="YPMLKKF"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="33262" checksum="FD793133A7B99950" modified="2023-09-13" version="1">MAFQPYTPKPVTDIFTHDTDINRRECRRVVPMRVLALGLGRTGTASLRTALKDLGFSDCYHMMSASVENPPDCLMWSDALASKYDGKGKFGRDQWDQLTGHCQAICDWPAVAFAKELIEAYPEAKVIITTRDVDSWHASTMKTVHWRATEPELKLVSKFDWGAGLYQPMLSKFWTEFWEGDFEKNGKRRFNEYYDEVRSLVPKENLLEYKMGEGWKPLCDFLEVPVPEGKKFPRTNDTDGFVDRCRKRNRMQMMNVLFRATVVGGSFAAIIFGASMTIRRFFGSRGSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHI4</accession>
    <name>A0A9Q8PHI4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766900.1">
        <property type="nucleotide sequence ID" value="XM_047911376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHI4"/>
    <dbReference type="GeneID" id="71992106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12228"/>
    <dbReference type="OrthoDB" id="4491390at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053178">
        <property type="entry name" value="Osmoadaptation_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111:SF2">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38111">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="458" mass="50547" checksum="429BDE17EFD9455C" modified="2023-09-13" version="1">MKGGSGSGSVINVVRASESGVGDGELVWDFNSGAEILGFDAFGGVGMDFGMLGGSGGGEAGGGIDLNQMILNAMPTATASPRTKQRHPHDDGLNEFWFKDRNGTPMDITRAMELYTTPSIIHSPAMEKQVIYSTFMDTYLPQRIGEQDAHFSFLQQLIQTPNLRPEVSAGLDAMSLVQVGSIFKDQNLLKQAVKAYHRAISGLLKTFQSKDTEFATDDYVLATVTVLANCEFFDEISQVGDGWTKHIEGQQQLLAARGPASIQSNLSLLLYSNMRHGALSHALLVRKACFMGTEEWRSVAWRAPYVDAATIFYDSALQVPAILERYDQLKAEDGVGKIDAILKDAAKLEQEMRTWFGGYQIRSKWNEHKLFELAPLEAFGTFSSLCPDRTLEEACVFPTFMVSYLICVYWDVTHFLRTSPISCGRQCRSCTWPSIRGTIHGIQKRGTKSRRPSCGNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHN7</accession>
    <name>A0A9Q8PHN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="1010"/>
        </location>
    </feature>
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        <location>
            <begin position="965"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1010" mass="106808" checksum="E9C3938F5CCFED76" modified="2023-09-13" version="1">MKVTLSTILLVGTASLALAHPEPEAKKAKAAFTRCGVPGLSCGKRDADPNPEALAYAKKAKGVLTRCGVPGISCGKREAEAAALFRCTAPGIACGKREADAFLIPGVSSKREAEAVAEAKKAKGVLTRCGVPGISCGKRDAEAGQAGFCGLPGEACSRAKRSALAIADAFAEADPDQSGLCGVDGQACAKARRSINEVGIAAEHVYNTVSAAEKRYVSYHTYDEKTKRWEPPSCGVRGFSCAKARDQLMWEHKRYAEAKKAKGVLTRCGVPGISCGKRELEEASIFGSLEQREANADAEPEYQCTAPGIACFKRDAEAKKAKAAFTRCGVPGLSCGRDAEAEAEADPKKKSKKAKAAFTRCGVPGLSCGKRDADAEALPLAKKAKAAFTRCGVPGLSCGRDAEAEADPKKKSKKAKAAFTRCGVPGLSCGKRDVFRCTAPGIACGRKRDAEALAEADPKKAKAAFTRCGVPGLSCGKREAEAEAKKAKAAFTRCGVPGLSCGKRDLETELALESRCGVRGYSCPLAREAKKAKGVLTRCGVPGLSCGKRDDLEDTEIEARDAEAEAEPKVLPKKFIVRKVPKKVRVSKGGILYRCGVPGLSCGKRDVEADGFEPVAEVIDEEEIEDVEARDAEPKKGGLLYRCGVPGLSCGKRDLEADGWEAITEDDIVGVAERDAEAKKAKGVLTRCGVPGISCGKREAEAEAEAEAEARKKSKKAKAAFTRCGVPGLSCGKREAEADAKKAKAAFTRCGVPGLSCGRDAEPEAKKKSKKAKAAFTRCGVPGLSCGRDVEAEHTLRLAMARDEEDSGLESGVEDLAKRCGIAGMSCTRNIDDEFHIDSNDDQNGFCGVNGEDCATTLRRNAEPKKAKGVFTRCGVPGLSCGRDAEAGALNEEDVAAAITEASPDYFEDECHKQGGECHAIAKAHRLFMEAKREAEDALAEGTNLVARAAFCDTHDCTYATRRWIEEAAEQADDAFDEYEDCHAEDGDCTVVKRALDELEETLEAAVKAL</sequence>
</entry>
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="18897" checksum="D6A528857EC4844F" modified="2023-09-13" version="1">MALPTKEDHLFCLECATIWFETAHTCPSCRAELYVSESPEEDDSDDESEAEELDPLQEWRSRNIELPDPEEDYLNTADAKTFQRTLLHLFDATTPINPRNLMDWPNAYDQFWSTKSEWDVLVLIDCKHLSGQIKAAVHVLLPSRYNEDYMGTTTRDMMCWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ03</accession>
    <name>A0A9Q8PJ03_PASFU</name>
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        <recommendedName>
            <fullName evidence="1">Cryptic loci regulator 2 N-terminal domain-containing protein</fullName>
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        <name evidence="2" type="ORF">CLAFUR5_12655</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767736.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ03"/>
    <dbReference type="GeneID" id="71992533"/>
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    <dbReference type="Proteomes" id="UP000756132">
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    <dbReference type="InterPro" id="IPR031915">
        <property type="entry name" value="Clr2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16761">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptic loci regulator 2 N-terminal" evidence="1">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="155" mass="17331" checksum="E38ACCADCE020179" modified="2023-09-13" version="1">MSPDYERKNNVYILAIGPESDGTYVAARKTEGWTRNDTRIERAIGKLWMQDRLKEGLTTQADISKSIAKKGLQAPTIKYELTRLPPGYSAFQRPQVQPNGTTRPQVGVFGHPNGHFTSINDFYVHFKHLTDCVKENDDRSMAFGGSGGENSLIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJI5</accession>
    <name>A0A9Q8PJI5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Exosome complex exonuclease rrp6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_13167</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the exosome component 10/RRP6 family.</text>
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        <property type="protein sequence ID" value="UJO23691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71993045"/>
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    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative exosome component 10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012588">
        <property type="entry name" value="Exosome-assoc_fac_Rrp6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049559">
        <property type="entry name" value="Rrp6p-like_exo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08066">
        <property type="entry name" value="PMC2NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="505"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="688"/>
            <end position="711"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="733"/>
            <end position="850"/>
        </location>
    </feature>
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        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
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            <begin position="782"/>
            <end position="791"/>
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        <location>
            <begin position="805"/>
            <end position="821"/>
        </location>
    </feature>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
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        </source>
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        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00043957"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
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            <dbReference type="EMBL" id="UJO23691.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="850" mass="95417" checksum="3507122A7F9956CA" modified="2023-09-13" version="1">MEDFNSLEANIKSSLLATIRSANSLGNEDLAFHRSLDSSVGTTLDQQNARLLGLAERLLGVSTANTELVRPPRLKDIDSVEGNWKAVVDVVDSLLERADTALDEFTGAVKRLSPGIEQAAPSKPPKVSRIAAALKTQELEKPQLHFDHVPKNDEVLPFKPLLQSKPHAAVPLETSPIASDEDTQESYAYHLISHSRLGVLDHEDGLKHLFSFSNKASRFEFFFPTSKSLKLRCWNIDPNVPNRYPHPYQLEIEQYRYPSSVYTISEPIMYQPFESTTATFVDTEEALYEMLEELKQAKEIAIDLEHHDSRTYIGIVSLMQISTRDKDWVVDTLQPWRRKMQCLNEVFADPGILKILHGAYMDIVWLQRDLGLYIVALFDTHYASRALGYTGGSLAFLLKKFINFDAQKQYQMADWRIRPLPQELFDYARSDTHFLLYIFDNMRNELVQRSDFSKPDHEGDKLWDVLQKSTEVALQRYEHPIYDAELGQGAGGWYKMLSRTPALFSKEQFSVFRAVHKWRDEVAREQDDSTHYVMPNHQVLSIAKAMPPNRLALLGVAQPTTQTVKLRADELVSVIAKAKEAGKEGPAMMDILNKIEPQAPRKSAPVQAAPAEATPEKTGPTASASGTASMADYKPSTSLPLRSSTSTFWGSAFDNSAHQKREMSSTSNVSLAVPLPPLTAEIFANPNEVEAEPPTPEPIPAPAVEVPADDDTFILKERNGKRKRTIDKFANVEDDGMAANTDEVSLTPVSGRDQEQREKAERKAARKAAKKAEKEAKRNGEEDSEIEDDTPFDYAAAPSILNPPREPRKSAKERKKEEKQKNPYATSLDAPKGMPRNQKEGPGRSMTFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJM3</accession>
    <name>A0A9Q8PJM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJM3"/>
    <dbReference type="GeneID" id="71992464"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12586"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="380" mass="41945" checksum="6F936BAD23BD2864" modified="2023-09-13" version="1">MSDSQSDSPGITSAPISSKKRKASIHSSSGSSCGSSIAGSNKSSRNPRKRRRSPKTVSRAASISDGDINNTSDLSLDQVSGSRDGGLNEPTKRRIWLNENDKPVYFRFLDLPGEIRNEIYDYGLVPGSVISLRTTADHIPSGVVSRQDLSMTLVNRQTHLEVETYYATNVFIANINLDPAADRLIPARHLSDENMSKIRKLVLNVDLITVDATDTPESLIDTVDFETLEHLNTLTNLTICATAFLEDIYNGRAQQLLEVVIGQIIQYIPPLCTVSYGSSNQETQDHIGDLLRKHLASVTGFTFAWPYRVHSHVLHAAAAAVTANQQIVQGAKNLAYEAKQDADWHQSMEEAEKRIEKLEEQAKAEEQEVKRLEAQSDGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJZ0</accession>
    <name>A0A9Q8PJZ0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-binding protein VTS1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">RNA-binding protein vts1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_13331</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA-binding protein involved in post-transcriptional regulation through transcript degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768173.1">
        <property type="nucleotide sequence ID" value="XM_047912479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJZ0"/>
    <dbReference type="GeneID" id="71993209"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13331"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09556">
        <property type="entry name" value="SAM_VTS1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000033">
        <property type="entry name" value="Protein vts1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037635">
        <property type="entry name" value="VTS1_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM" evidence="14">
        <location>
            <begin position="576"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="239"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="547"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO23807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="640" mass="68574" checksum="A65755B7120FED97" modified="2023-09-13" version="1">MSNIIGNRNSTPEASTSSLSGSTLRPPTSRTMAPAGHHLRASADMGALSATSPLATRGIRPASEVYYSQFSQGANAGNEQDVAEKAAQQWIADIDQYETTLEEMAAATLDQDFKDELSAIEQWFRVLSEPERTAALYALLQQTTQVQIRFFIQVLQQMAKSHPMSGVLSPAAFGEKDPMSSRMNDAMNKLNVEGSRGSFGFGGKPPPSPGGKRMSGLDPNTIKSMFPDAANAIEDQKAEFQKTTGSLPKSNRNSAVGDRGSQYMPTISAPDEEQSHHKKNGSSIPSGPWRSTSASAPENQAPIGRPKSSSSHQPQGPSPMGQFSQPPQSAGLRSSRAFPLTSDSNIQSQTANIGDGNGNNFGMPMLSPYAPGMSWASMTNTPMAANFSQQQSANQADMVANATAMKLAALSTVNNRIQLDDVRKYRRARSQEGQQPLSPGVPHTLMTNELGQILTPQQAAALQQQHIAQMQGRRSRPSSPGIAITGPPGGYMGQPGMHAPQNNGYLAAFDGGMGGLNNGMAGMNLGNFGMGGMGGMGGINEGYLSDASDINRGRSPRGRRGSSKPPEDPTDLSLLKNVPDWLRTLRLHKYTDNLKDMRWQDLVQLDEDGLEKRGVAAKGARTKLLKVFEQVREAQAEGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK83</accession>
    <name>A0A9Q8PK83_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768337.1">
        <property type="nucleotide sequence ID" value="XM_047912153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK83"/>
    <dbReference type="GeneID" id="71992883"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13005"/>
    <dbReference type="OMA" id="ITWVENW"/>
    <dbReference type="OrthoDB" id="4126315at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="15409" checksum="EF1007E135F08836" modified="2023-09-13" version="1">MPLPTAPPSEVLPLQSFSLQVTVHIKPEDLDAFHKAMNPVFETVCNEPELLYFEIFQDPDSPGTLSWVENWRGSVEWLMKVQLQKEYYRPYLEATEPMFIKEREFKVLRRAPGYVSGKRENFREAFVGELKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKS0</accession>
    <name>A0A9Q8PKS0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768634.1">
        <property type="nucleotide sequence ID" value="XM_047912789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKS0"/>
    <dbReference type="GeneID" id="71993519"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13641"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="103" mass="11807" checksum="15A1CAA20DD76327" modified="2023-09-13" version="1">MGRSYDGTAATSASTQHGIRRSDLVRQRYAISSDRYDPARHQFQGPECSAWTTSRRAQQRSRDDQTLAVVGRNGYRVHDDQVAFRNVLDCRIYYEGDPRHSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKS4</accession>
    <name>A0A9Q8PKS4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase VdtF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_13940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768565.1">
        <property type="nucleotide sequence ID" value="XM_047913088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKS4"/>
    <dbReference type="GeneID" id="71993818"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13940"/>
    <dbReference type="OMA" id="EKGHVPH"/>
    <dbReference type="OrthoDB" id="2962696at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="306" mass="32611" checksum="B2F5DA9EB1A937DB" modified="2023-09-13" version="1">MAETHHFDVNRLFGVKGYVAVVTGGGTGIGLMAAQALSANGAKVYITGRRTDALEKAASEHTPDQEHTGGQIIPLGPCDVTKKEDLQKVVDELSKKEKYINLLVCNAGIPGPKGGGGEEDAKDLKKKLWENESVEDWQTTMETDVTSVYFTTVAFLPLLQSALGSQGASNDTGPAGVHEDFAPSVITISSMSGLMRHAQGHFAYNAAKGATVHLTKLMSSEFQEAKIRVNSIAPGYFPSEMTAKESDERNKSGFPEGKIEQTGHVPLMRAGRDEEIGMTVLFLAKNCYVNGQILAVDGGVLNVVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKZ9</accession>
    <name>A0A9Q8PKZ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras guanine nucleotide exchange factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768786.1">
        <property type="nucleotide sequence ID" value="XM_047912658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKZ9"/>
    <dbReference type="GeneID" id="71993388"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13510"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF354">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="105"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="8">
        <location>
            <begin position="754"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="937"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1182"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="609"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="639"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="677"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1183"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1246" mass="137965" checksum="F6F1096D518DBB2F" modified="2023-09-13" version="1">MDTSEGPVSIGAESRHSRPISENWHTANDGTWSESGASRRPSAPATRIIHSSTASATSSRRKPSQNIETTTITTAGFVSHITPPQTPVSPSPDSEMDLQPAAQSLFHNYLRAMYSFAPSAESMPDDDASQSAVALRPGDLILVHCVHANGWADGTVLNTSERGWLPTNYCEAYDHPYLRNLLNAMTQFWDLLGASEDASLSTFVRQDYIRGLIAGVRYLLERADCLHRDAATVKRHAGVRRMRKGLLADLSSLVQIAKKLQETIGEAFAGEVIHVLLDDLISKAFRMVTRAASFTDVWTTETKKGESKNAPRRPLTPPIESIGLAIDTQASVNTKRDTVDAIDSAKHFPEISETSHTSSHETVANEEQKFPEERAPRLSMAFSPPDGLAAHRVSLVPSESNHARSGPLALEQLAKVHDICISHIGAFIGHHLHSRPSAELVATTERLVQVCRNLLAIIDEVYTHDPQKSSLVQQSKDEFEIKLEELAKSTQDVFRFSDSEDDDVIMLPDKTNHLISVGTNLIRNTGECVVKTRQLIEQIGDFELRTVQLSGSNHEIPRRIDSMPQDDALDRRSSKRISIKRMSKILMPPPPPVIKDDTPLEEEQDVAEPSTTEKATVVESTTTAAPEQKPLPPPPAVQRRSTMGGSQSSSLHVDTLRSPRSVRADSTSPARKDSVGFSISGSTDTFCSSARDSRTTIVSVSTRATTPDKEAPSDHAMMSSFASISSMRSLITDDSIDGEALLQQTYAHELTFNKDGQVTGGSLSALVEQLTTHDSAPDPQFVTAFFLTFRKFCEPREFAQALIQRFDYIGDSRTVGTPARLRIYNVFKGWLETYWCADADKDALGEIRFFAMHKLKQVLPAAGDRLAELTKRITEGYANGKSNGPLVSGVGKSSMSIGSHLVNNAANVPEPLITLKQLNAIRVANGGGAACSIIDFDPKEIARQITLLVMKEYCEIRPEELLSMDWTRPNTKRAKNVRNMCQLNTDLSHLVNDSILAPEDPKKRAKTIKQWARIGTACLELSNYDCVMAIMCSIHSSVIQRLKKTWDLVKKPIKAELDALDKVVDMSKNYSMLRKRLESPTAPCLPFLGVYLTDLTFVLAGNPKRRELPGSTSAEGGPISVINFDMYMRIAKIISHLQKFQVQYKLKPVPEVQTWLEQYLQRMRGGHDDMVSIFHRRSLAVEPKQEERKHTLSFRSESDAQRPPTAGGHHATPPPTTMERFDFFHKSTSFMNMRSQTTLSIHADPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL25</accession>
    <name>A0A9Q8PL25_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-terminal kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768814.1">
        <property type="nucleotide sequence ID" value="XM_047912922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL25"/>
    <dbReference type="GeneID" id="71993652"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13774"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="743"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="783" mass="84134" checksum="8390817144C46120" modified="2023-09-13" version="1">MDFLKSAVASIAKGGPAFGYSFADRVDVDQSIWTLHNGTKRPKEDGSKCSIFSFDIAANRSRLPLARNALRKFKTLRHPGIVKVLDTIETDTLIYIATERITPLNWSTRRKALAEESLKWGLHNVAKTLKFINDEAASVHGNIRASSIFTSESGEWKLGGLDILSSMKEDDAVIFTQGSLLPDIGRYSPPEVAKNGWGGVRGGPIHAVDAYNYGILVTEVFNGGFSASDQIGSTKNIPLNMQNSYKRLTHAAPKMRLSVGHFLEQGTRSGSFFDTPLIELADGIDNIGLKSPDEKEAFLSELETIVEAKEFPEDFFKVKVLPELLKAVEFGGAGPKAFSLVMRIAQTLPEDEYGTQITPVVVRLFMSPDRAMRVCLLDNLPLMIDHLSQKLVTDKIFPQMVTGFGDLAPVIREQTVKAVLVVVSKLSDRVINGELLRHLAKTANDEQPGIRTNTTICLGKIARNLGASSRAKVLSAAFSRALRDPFVHARNAALMALAATADVFSEEDCATKMLPALCPSLVDKEKMIREQANKTLNIYLDRVRKYSATLPDTALPPPETASAGGTRVSTPQPQPSSQWMGWAISSFTNKIGSATGEIQTNGTGGLPVTSTPSNGVSPRPSPGPHSASVSSVPKVSSGLRTNAVAPVQPIEQDIPDEDFGDGWGDLDDDPELAATWGAESASSPQHSSKPSTSSASYDDGGEPDFEGWLNAQAQAKAGSKKPLPKGLAKKTSTPPTRPGQPRATSTKSAPLTTATKTAPKPAAPKPAAAPAEEEDDEWGSAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL43</accession>
    <name>A0A9Q8PL43_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_13519</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cut8/STS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768791.1">
        <property type="nucleotide sequence ID" value="XM_047912667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PL43"/>
    <dbReference type="GeneID" id="71993397"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13519"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1590:FF:000001">
        <property type="entry name" value="Tethering factor for nuclear proteasome STS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <sequence length="437" mass="47698" checksum="162263C906D6594E" modified="2023-09-13" version="1">MPACKHADLTFEPSEHAASVGYRRPTVRERANATRLGSGPGAEQLDVKPSTFPGPLVLPGDELSFDPKYERQDVKSWSGCTGFYTAKRRAIYVVPTPRLSPGVSECLPTPNLKPIKGPGRSHASTIPSPKTDDILDYLSAFYHGMPVKILEKPALSLTRWENTIGDENAPARVGLFLGAETVGVRVRPSPDRILGAQLNLDDILDAAISILPKDAHALLMIVDHDLYEDEEDDFCCGRAYGGSRVAVVSTARSKTEHAWPASHCRKFVDDNCRESEPDAGRQKNEAKVIRYASPSDRSKSAMHSAVDALQHLAVRKDLVQLSNLWLGRVCKTASHELGHCFGMDHCVYYACVMQGTSGLTEDAGQPPYLCPVDLAKLFRVTGADEKAHDTALLAFCERWRHDKLLAAFAAWLKVRLAELEAAGAPGGGSEEEAIMLD</sequence>
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    </evidence>
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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763667.1">
        <property type="nucleotide sequence ID" value="XM_047906102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR33"/>
    <dbReference type="GeneID" id="71986832"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06954"/>
    <dbReference type="OrthoDB" id="3644624at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="587" mass="64313" checksum="D910DEEFEC450A61" modified="2023-09-13" version="1">MLARAAKCKDLSSVTVGATVPVPDLDDDVYRLNFESERTISEDFAFLTANEDGPTRVSAASLLATRQVASSVISIACNQGVHPNVRHAVGEVVAVVRAVADLPFVVNLNFVEQADRLLSVILNVHRNRILGRLGSSRYKVPEGCYADTTRTLLGDGLRPISMLIESAARPHSAEMARSEEDINAFLRCAKKLDGHDKGSNTISSYKNAIKAAYALTLDGVSLQKRLRRLGLPMLPTSSKELRHLPALANYWRICLHLTRMARTYRKAFRHLQANFVSYGSREHTVHAEIQLLVYHETSAHALRPRIISASKKPCFLCHTFINAYGWYAGQETHGKIYPNWNIPAATQFPLDVRRQIEYASEHTARVVANTIRVLKERAGAISWPPDQAQSVINLNLTIIPSAAPSTIIDAVASVADIKSEHMKNQDASPPSIKEDLNLARAVSGVAVPPPNDQEQDPVETTENATNLSIFDARLADIQPTDQASVAAGAVQQTSIPSSTHSSGMKHLFQYGPDVLEIEHGTYEVLDMLSKEAADGIVNLGRLESVEEGGKELTFKRPDGAGALILQLQHSGFADVKIRLHWDSQGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URL1</accession>
    <name>A0A9Q8URL1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_10244</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764206.1">
        <property type="nucleotide sequence ID" value="XM_047909392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URL1"/>
    <dbReference type="GeneID" id="71990122"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10244"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF3">
        <property type="entry name" value="HOLOCYTOCHROME-C SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO19840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="324" mass="36261" checksum="BF56A849449C4E0B" modified="2023-09-13" version="1">MGWFWADTTPSATIAPHPIPSNSSAQPPPSCPMHNKTASALSGKPPAPAQSERPSACPVKHDAPKSSSASPSYISKLNPLNYMPQSISNKREASEQNINLPLDREASTIPRGGGQGTWEYPSPQQMYNAMLRKGYTDTPAEHVESMVAVHNFLNEGAWEEIKGWEDRFREGLGKAWERCAKGEEGYSQSQTMESLRRQNDREEYYGPSLLRFEGRPNDITPKARILGLMSSVLPSQYPDNPPFDRHDWYVERQGPGGQKKELRYVIDYYSGPPEPTGEPVFYLDVRPAVDGPTAACERLLRWGGDVWWRASGGSVREELARQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTB4</accession>
    <name>A0A9Q8UTB4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-saccharopine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765993.1">
        <property type="nucleotide sequence ID" value="XM_047908423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTB4"/>
    <dbReference type="GeneID" id="71989153"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09275"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF24">
        <property type="entry name" value="HYPOTHETICAL FRUCTOSYL AMINE:OXYGEN OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="440" mass="49598" checksum="975846C1E9575209" modified="2023-09-13" version="1">MAELKQSSILIIGCGTWGASTALHLARRGYQNLTVLDPYDVPSTISAGNDINKIKGWADNYSAGGGDMKDYVRDRVSREATEAWDSDPLFKPYYHETGYVIAASQPKHIKKLYHEEQPTPEKGFVELNTAEDFRKTMPEGVLTGDFPNWKGWLKKDGCGWAHARKAMTAAAMEARRLGATLLTGSPHGDVRSLLFENGDVRGAVTADSIQHRAKRTILCVGANAPQLLDMKGQLRPTAWTLAHIRLTGEEIKLYRNLPVLFNVERGFFMEPDEDQHELKICDEHPGYCNWTTSDKSISIPFSKHQIPLRSEEGVRLFLRETMPHLADRPFSFARICWCADTPNRSFLISSHPDYPGLTLGIGESGHGYKHIPVIGRYVADCLEDQMDGTMKQVWRWRPETAVGRNWEDVQGRMGGSYKVLNLADMPEDQWTQIRYDSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTR9</accession>
    <name>A0A9Q8UTR9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766575.1">
        <property type="nucleotide sequence ID" value="XM_047908223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTR9"/>
    <dbReference type="GeneID" id="71988953"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09075"/>
    <dbReference type="OrthoDB" id="3644790at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="29846" checksum="78EE08DE102CEEC9" modified="2023-09-13" version="1">MSSTTAETTSVLPALYASGNHSDLIVRACDGREFRVHKCIVSSKSGFFEGACRGGFKEAQAGVVEVEEDGEVMDALFRHIYENPLEWAPLAADSFEILRSKATTETFGLARKLRAASDKYLVTGLKRPTELAMVNRLGRLPIEENVAFTKLYIACFSHDADVGILVRHSALSNMCLRFKRVLEDAEAWSLLGPLTELVQLTVICAIQRSEYDAIAEGTAAKNLKGLAVSKTYRRYADLDRVWPVPEAVFQEAISSFNAIRDELTRVEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUH2</accession>
    <name>A0A9Q8UUH2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767310.1">
        <property type="nucleotide sequence ID" value="XM_047911526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUH2"/>
    <dbReference type="GeneID" id="71992256"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12378"/>
    <dbReference type="OMA" id="DPREWNR"/>
    <dbReference type="OrthoDB" id="5338512at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="47367" checksum="6F9A2705E705E3E8" modified="2023-09-13" version="1">MGYNCQSGTCIAVTKAEAASSSTSLLPTTASTLTTSTVTSTSASQASSTAGTTITPVALKDAEDDNSFSGKSFAAGFVPGLLLGALVVGLLVFCCMRRKKKAASYVDEKRYSSGRYTLTDLSPAAVSRRPTVHGRSISEPMADVAMGHRTDFLKSSPPRDGPNGGLQGYTMHVHSPAKNPTTPAAQVQKSPLTKGWSFSHSPFVNQATTPVPTQPPLPAHLKRGSITTFQIEPVRGLKKQRSQKNLRANIPNATSRSPPTHQGTQSRPDTSRTGSTETMTVIMDTPGIQTHTTSPSTLPTAVHCPQDAHKSHHGIIVPASGKTWETSDSDDSTPIEEQPNEYTPTRPGRNSNTANIGKTLQSPCTPSNYPPPPPVPESQMNSLMPPGMGVQGNRDSQWRNTAMTTFSSIMEKAGWGRNSVQAVKEKRGAEGEYGMGPDPREWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUI3</accession>
    <name>A0A9Q8UUI3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11738</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767193.1">
        <property type="nucleotide sequence ID" value="XM_047910886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUI3"/>
    <dbReference type="GeneID" id="71991616"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11738"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="265"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="57719" checksum="77F3C29887CF26D9" modified="2023-09-13" version="1">MLNARNETEKNTMSGVRTTRQREHTRSGLGNLADALLRPSTTRGLLESTMAPSMPNGKLDDFIQFAVERMIGGQAVKDREISLLTTEYLAQPSAHLAILDETVIAVNDAERHYYHQLQTAEDGSDYIRRNPDRTIVQRANRLDKVHGAALLLVETCHIAFEALGRASRAHQAHLDRTTRSPILIALGRWLTEYNTRLQDAVQSKYEVKDEFDDAVRVCPGRKVPWPMSKLHPQVRDQIQRVAIEEVKKIPAFEPLPSVFDDTIKWAPVHHFQGGMSKATLMVGVDSTTRMIKMRMVRKDTLQSDRQWGNVKFWRGDLRNGHNMLPTEYVSHRLVGGAPGSRFVPKILADVELNPHQLSYHMMMEFAANGDLWDVFDAHRKARIAVPELFLWLVFQALIEAAVVMKRGNSDQDVASRADWMEIVHCDLKPRNVFLDLPHEEHFKLYPRPKLGDFGCAFLTTPKDTVNPLLWCHGGGTRGFLAPEQDAHADGVTGKLVDDFPLISHTNVWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVD6</accession>
    <name>A0A9Q8UVD6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isonitrile hydratase-like protein xanA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768224.1">
        <property type="nucleotide sequence ID" value="XM_047911737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVD6"/>
    <dbReference type="GeneID" id="71992467"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12589"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV1931C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040366519" evidence="1">
        <location>
            <begin position="30"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="24703" checksum="7EE6D50CC95E766B" modified="2023-09-13" version="1">MVPSKVRVLGLMFLSFNVLDLTGPCEVFGSNFLPGERSIDIASATESCTSSEGVTVQCTFSFDELLNDTSALSDYDILLVPGARDDYIDAALKDDKGLLQIIKTFATLENDGKERWLFSVCTGAAFLAHVGVLSGKTATTHWTYLDKLKETCKGAGEEADIVRKRFVDAGRSKTGVRVVTAVGVSCGMDAALWIASVVYDLEQAKGIAKGMDYAWAYAPNDDVTEGWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVS8</accession>
    <name>A0A9Q8UVS8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768601.1">
        <property type="nucleotide sequence ID" value="XM_047912999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVS8"/>
    <dbReference type="GeneID" id="71993729"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13851"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="27326" checksum="F6823733243118C2" modified="2023-09-13" version="1">MAEAEQSKQLQDERHIRSLAEIAEASLLKELKSCLRLQSRKAIFACGGTVNFTPDNKQKAALANGIGGIPSIDLRFGESGKGMTLTLPIQTDNSSQFTALLSACQPASFGRSNEEVFEEEYRKASKLDRTAFATNFCPYEAGIIDVVAQLLLSPSSQREHKRSIKAELYKLNVYGAPSGKFKAHVDTPRSEDQIGSLVVCLPLDHEGGQLVVRNSGKELTFDWSQRGDTDRPDVKWGSLLQRLRARSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVZ6</accession>
    <name>A0A9Q8UVZ6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_13443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768738.1">
        <property type="nucleotide sequence ID" value="XM_047912591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVZ6"/>
    <dbReference type="GeneID" id="71993321"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13443"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO24372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="506" mass="56512" checksum="848465922AC33EB0" modified="2023-09-13" version="1">MDQGSTFDQVKALCAAYAKHLHKNHHAIATVMTAYQSYSVTADEIERSIECLTSIDEIKRHLVTGRTKRVCTFFPLNLPVYSLVLFAVVPSLISDEVFLRPPQKMIPVFRQLLGSLCLAEFFPNIHVSFSDRETFVRELVADADVTIFTGKESNVRLVLQKTRKNSIFLFNGWGCNPIVVAADADIAKAASKAAEAKLFNARQDCAGPDNILVHKSVADQFLAQLQHKVSQAKVGSYSDPDVLVGRIAEDSALVRLASFLLKHQDKIVYGDGIDFANTIVWPTTIVAPLAEQTNYEEFFSPIFYINIFDDDDQLARYFDSPQYKANDMYVSLFGTSAYVKTLTKSIVYHEQTILDVERGNHAYGGYSFGASFVASNGMTDPRPILVPKEISEFIQGQAKAQNPISTTPKKLSAAQQKCIQRDVTDFITQHFGDNLVFGFVFGSLLANKATNASDIDNMIVLKIHNAEQEDAYLMWLRKYHAEMGMTFDSVYPTESSRRHTSMSALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXM4</accession>
    <name>A0A1P8YXM4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecp43-1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Extracellular protein 43-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ecp43-1</name>
        <name evidence="3" type="ORF">CLAFUR5_01523</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">0WU</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943089">
        <property type="protein sequence ID" value="AQA29260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXM4"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573450" evidence="1">
        <location>
            <begin position="20"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQA29260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="94" mass="9969" checksum="04C77D9177CC282F" modified="2017-04-12" version="1">MTKLLLTCLFSFAVGFANAAAMAADPQDGLSGISCPENRWHVCYAAGACEKHQRPHACATGFARHPHCPREMTGCDADCCNLCESTNVGYGNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4M0</accession>
    <name>A0A9Q8L4M0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755156.1">
        <property type="nucleotide sequence ID" value="XM_047900732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4M0"/>
    <dbReference type="GeneID" id="71981462"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01584"/>
    <dbReference type="OrthoDB" id="3511549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="44"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO10790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14101" checksum="01FFDA98F270444D" modified="2023-09-13" version="1">MPHEQKPVIYTSSNNLQTSGAQTEGMIRQNAIVDVCDDICASRMIAKPRTASAVHHHGEENTIVFAFSGHGAIVYEGGKMRQNLAPGDYALIPAYAEHQEVNDSDEDVVWAIVRSGKAPIVVNLPGGWGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5R5</accession>
    <name>A0A9Q8L5R5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arginine-hydroxylase NDUFAF5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755610.1">
        <property type="nucleotide sequence ID" value="XM_047900933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5R5"/>
    <dbReference type="GeneID" id="71981663"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01785"/>
    <dbReference type="OMA" id="YEVVYGH"/>
    <dbReference type="OrthoDB" id="16816at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="366" mass="40507" checksum="CDC7A3EEC7D1B409" modified="2023-09-13" version="1">MRLSLLRSIKRPCLTASTISKACFLPAASPRFYAVQAPGAPTVEVFDARTKWLHKERAARNVAQSRQVDYLRDEVAARLCDRILDINRPFPRVLDFGANSCNIARILTRPDPDPDSAKPSIEPIAKKIGSITCTDTSPSLLYRDQDEPFNNDIEVQREVLKNSEYLPYDAETFDLVLSSMSLHWTNDLPSVLMQINNCLKPDAPFVAAMSGGDSLFELRGSLQLAEQERLGGIGTHISPLADVRDVGNLLSRAGFKLLTVDVDDIIVDYPNTFALMSDLQAMGEANAALRREPGGISKDVLLATEAIYREMYGEEQEDGTLTIPATFRTIYMIGWKEGANQPKPLERGSGDVNLKDLFDAAEGRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6S5</accession>
    <name>A0A9Q8L6S5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755609.1">
        <property type="nucleotide sequence ID" value="XM_047900932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6S5"/>
    <dbReference type="GeneID" id="71981662"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01784"/>
    <dbReference type="OrthoDB" id="3885851at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="237" mass="26812" checksum="778C11B0F59455C4" modified="2023-09-13" version="1">MSAMQQVFATTELFDYILSYVLDATHCIADQEDPRSVKTHHNARLLQNLLRSSRVDRQWRNHILGSTYTKGALFYISDPTTQRAWEQTHPRSSTGAVYRPVDVHAPTLNPIIQTTFPSYNFRFCFNTSVGEDCQATPRHSAFLIITKRELPNLQTREATGQGCRIPEMLLAQPPCVALKAAIYEEIDDMKEYLGRTTSLTDPVIRCEQGLTLGMVHERVGAMFEKHPDVAAINLTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L794</accession>
    <name>A0A9Q8L794_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kynurenine formamidase</fullName>
            <shortName evidence="3">KFA</shortName>
            <shortName evidence="3">KFase</shortName>
            <ecNumber evidence="3">3.5.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Arylformamidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">N-formylkynurenine formamidase</fullName>
            <shortName evidence="3">FKF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>N-formyl-L-kynurenine + H2O = L-kynurenine + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13009"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="3.5.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the kynurenine formamidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756390.1">
        <property type="nucleotide sequence ID" value="XM_047899439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L794"/>
    <dbReference type="GeneID" id="71980169"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00291"/>
    <dbReference type="OMA" id="YWVIYIH"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03014">
        <property type="entry name" value="KFase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027519">
        <property type="entry name" value="KFase_ver/fungi-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="5">
        <location>
            <begin position="38"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HGGXW" evidence="3">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="305" mass="34415" checksum="CC2691B1C2BA2238" modified="2023-09-13" version="1">MPATPTGDEWPQFRKDIRYSGDSNLNTLQTCIPRSTDNKRHRIWIVYIHGGAWFDPEQTASTFDKAQDILLNSSIADHVGGYASINYRLSPAPAHPTNPSNPADPARNAQHPDHINDVLSAILHLQETYRFEDRYILVGHSCGAFLAFQVAMKRYWRSQYESTYGLEMNVMPPLAVLGIEGLYDLPALVKYHDDLKQPIYHNFVESAFGPNATNWAAASPTNADYKSSWQDGKLAVVAHSHEDELVEWDQPELMMKALSSQGFGDSGNRRGKLIELKGKHDQVWSNGTEVARAIEWTIKEFVSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7M6</accession>
    <name>A0A9Q8L7M6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02278</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756714.1">
        <property type="nucleotide sequence ID" value="XM_047901426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7M6"/>
    <dbReference type="GeneID" id="71982156"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02278"/>
    <dbReference type="OrthoDB" id="4454541at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF33">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="597" mass="66076" checksum="13B1353B3AD199D7" modified="2023-09-13" version="1">MDQPAEEASPPAKKRRIPKACSACRRSKLRCDENRPCSRCVSTGVDCVYIERPKDPIAERFERLESTISYLQGRLDSAHGQTSPAASYVSGPSQADTAPTQQRSSFSVPGTFTGLSSFAIRHPPTLDLVAAGVVSVQDARYWFETFFLGCDRFIPAFDPAFDTYDSVRTRSNVLFDAIVTYGCRAATGVLSKQYQALSSLLRRRTSDLVLLMSQVSHAMPRMEDIQALLVIASFSESGAVLSDVALKAAVNAGLPDRLDDLFAMTIANNQDRAGDIAMLFRQARVWFAVFVLDQILSLDGGKPPSVYIRSSPRRIRALISHSQRTTTDLRLFAQVELNAIRSSFYSSVASGSPGATDQVQISQTMAGSLLDLRMWLSEWHAIELNDTTMTTEHPVMLLNLQIQHAWAVLTLHLPALTASGVENIAFMTDAQRNIAVAAKAASEHHLQLLLTNVEMPGNVSTKPYVANLKYAMEFVWAKNAFSVLIVLRLGILLGDHIDTLALRLSEARAFLAELDKAGMGTNISYIRILLQTVEKCERAIRRCARHGQARESTESSDIDFQSFVPKEFTLEWDFPGLNLCYIPFDWQDLFLDFGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7Y2</accession>
    <name>A0A9Q8L7Y2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756927.1">
        <property type="nucleotide sequence ID" value="XM_047899673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7Y2"/>
    <dbReference type="GeneID" id="71980403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00525"/>
    <dbReference type="OMA" id="AFRENNQ"/>
    <dbReference type="OrthoDB" id="3903686at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="451" mass="51857" checksum="E397E351A4F665DE" modified="2023-09-13" version="1">MSLLTLPTELLDHIFSYFEWDRTKQLHPVKDDLISAGLTCKKLRTALLPSIFKEVTLRLRWVGGELAEPSLLKLRVQSPQLMRHIRCVTLSTECEDCTHCAQKDHCQPFVPPDDQQDWLAFKGEDASHLASEYRSRVDAFARTLRTNAEVPYWSTDASAECIISASRAARLRCRTLDCLAIVMLCIPPNVHSIILKSNLVGRNHESKNDFSMQLLATSMEVLADRLQELTLVSMAYHNQSRRQIANDANALVEDKPLPISLLNRSNIQRLVLAFRENNQFSASSPTLTHRAYERWQTTSIRELDLRYMRADISEVLNFTKGFPALETVRIRDFVLFIAGRAPGRQELERHVWLHLAIELRRQLPNARIELSNLFRPASYDQLTESAIRWIVQEAIPEGAVIDVEREQRLTEDYLSFAFLWAAEDGRRPAHSPVSDKLWASLSDEAMTRRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L830</accession>
    <name>A0A9Q8L830_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757001.1">
        <property type="nucleotide sequence ID" value="XM_047899198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L830"/>
    <dbReference type="GeneID" id="71979928"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00050"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="135" mass="15364" checksum="09E351E516345EC5" modified="2023-09-13" version="1">MPSSIVQPYRTRYTTMERQLYSSGDTGGRTHEGYTTWSTTTGQQHATHDLIRAQAIMPAYAGAAATPTSHYSFPPQRSSLYRRCPECPEGRRWLDRLHCLQPSNMVVEGVKKLWHDGASTSRACEKPGQWKRKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8M0</accession>
    <name>A0A9Q8L8M0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757243.1">
        <property type="nucleotide sequence ID" value="XM_047899843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8M0"/>
    <dbReference type="GeneID" id="71980573"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00695"/>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="OrthoDB" id="425211at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000003">
        <property type="entry name" value="3-methyl-2-oxobutanoate hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="350" mass="37129" checksum="7D59DFA4CDA60C21" modified="2023-09-13" version="1">MSRALMNKIPQLAHASTLPGARIQPSIRTAAAAVLHHVPTTSTPVRHSSHSPIGAVSSSRKKVTIQTLQTLYKRNEPITMITAHDFPSAHVAEHAGMDMILVGDSLAMVALGMEDTSEVLLEEMLLHCRSVARGAKASFIVGDLPMGSYEVSPEQALQSAIRLVKEGRVHAVKLEGGVEMAPAIAKITAAGIPVLAHIGLTPQRQNALGGFRVQGKSVGGALKVLEDAKAVQHAGAFGVVLEAIPEPVANAVTKRLQIPTIGIGAGSGCSGQVLVQVDMAGYFPPGRRVPKFVKKFGDLWGEASRALETYRDEVKSRSYPAAEHNYPMPADQVAEFEKAADSVERGHTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9N8</accession>
    <name>A0A9Q8L9N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757728.1">
        <property type="nucleotide sequence ID" value="XM_047901707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9N8"/>
    <dbReference type="GeneID" id="71982437"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02559"/>
    <dbReference type="OMA" id="HEWAESK"/>
    <dbReference type="OrthoDB" id="5381976at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="16449" checksum="23C9EDD81D5F9135" modified="2023-09-13" version="1">MASQPRASTETTSRTRHDTTTPSRPASIAPTDTTSILTAVDDGEATPRALSLAPTLVETRTTYRGFPSEAAYRAAFHEWAESKRYNQQDDTALIGFYGETTMEELAARPRAEFGLSRKWRERKERKAQRQQLQQQQQQGRRQTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9R3</accession>
    <name>A0A9Q8L9R3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757780.1">
        <property type="nucleotide sequence ID" value="XM_047901726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9R3"/>
    <dbReference type="GeneID" id="71982456"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02578"/>
    <dbReference type="OrthoDB" id="3647231at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="48"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="39773" checksum="F77CF6E81A94256B" modified="2023-09-13" version="1">MTSKLYADCRLLDPNTHIRLLQFQDGPSDMVACAMSVHALADSPVFNGISYTWGESECTAHIVVNNHRLSVTPNCQYALWQARLNSAASYVWIDSVCIDQASLNEKEPQVALMGTTFSHACRVLANVGPHDAVSLRIQKLCDELRSYLRLETDLPYILAVEWHPFGRDRVSRFKGWAKGKTAGELKSAALDLCTFEQRRYWSRLWVVQELCAVGKERIDVLCGRSVLEWAILGDLEALFSIITESEESRHTWHGSDSLKVPLLIEEAIMVARTDRNADEPSDAPFSIMGSKSPRLLKARDRREVITLRQLSFWIATYVEIVQDSGRGAENIEPDVHDGRNAYEDDTIVDRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA52</accession>
    <name>A0A9Q8LA52_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00948</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757349.1">
        <property type="nucleotide sequence ID" value="XM_047900096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA52"/>
    <dbReference type="GeneID" id="71980826"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00948"/>
    <dbReference type="OMA" id="YTLWIIV"/>
    <dbReference type="OrthoDB" id="311279at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="96" mass="10549" checksum="CC14257DDAC4EBF8" modified="2023-09-13" version="1">MAANTLLDRVVGLAMLILASAVFLYYTTWTLLMPFVDSGHPIQTLFPPRVWAIRIPVILLLLGGAVVGSFLSVVMIRSNRKKALKAKQKAQAQKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAD4</accession>
    <name>A0A9Q8LAD4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758158.1">
        <property type="nucleotide sequence ID" value="XM_047902960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAD4"/>
    <dbReference type="GeneID" id="71983690"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03812"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13540" checksum="FE9312CEF413FD39" modified="2023-09-13" version="1">MADQDRLSMAEVKEQILANCTTLWPIFHPTSSDDEKEDDHPELTINTIGGSANIFASVVYDNGNGFYVMMNGPEATNQRRACEKLLAMTSDILANYWKKHVYYEAHLKVKKGGSGGTYYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB05</accession>
    <name>A0A9Q8LB05_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
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        <property type="protein sequence ID" value="UJO14051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_02869"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ethanolamine kinase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Choline_kin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="336"/>
            <end position="408"/>
        </location>
    </feature>
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    </feature>
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            <end position="150"/>
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            <end position="206"/>
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            <end position="286"/>
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            <begin position="87"/>
            <end position="96"/>
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            <end position="148"/>
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            <begin position="718"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB98</accession>
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    </gene>
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        <lineage>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040297010" evidence="1">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="86" mass="9695" checksum="9EB5603B650BE9B4" modified="2023-09-13" version="1">MNPLTLIAFCLHTVHVYAGPYSTEGLSIRDAGKVIQSRWAHGDLFKRKICCSCVFSCCTKGCPTNDNYSFYKELDEAEFPGDKHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBP4</accession>
    <name>A0A9Q8LBP4_PASFU</name>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
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    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02614</name>
    </gene>
    <organism evidence="9 10">
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF5">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO14289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="452" mass="49205" checksum="023EDC5110613AFF" modified="2023-09-13" version="1">MSLPDEKLSEDRFEEKEDRLPYGSDYAEDPILESRSNHRSPLAPPSHTDNNFLLCNAKLDGLTDDLHLTGYKYNVALTVFYILYVLIDIPSNWLLKIVGGGRYLPLLAIAWGIVGTSMGAVKSYGGLIACRHLLGACEGGMFGGIILYLSMFYKRHQLMFRLGVLYCAAPLSGAFGGLLATGLAEIRFGGYDGWPWIFFVEGSITIVVAMVAFFFLPNTPGGARFLAPEEQSVAARRLQADQGAAASGRVEEEHFNWQEVRSALLNLNAIAMSINFFLILVPIYSYSLFLPTIIKGLGYTRVTAQLFTVPPNFLAFLSVLAFAWTSDRIKMRGPLIVLGLSLAAVGYIMQLASQQNAVKYAGTFFVAVGAFSCSPLVLAWLSNNLAPHTTKATGLGFQVTVGNCGAFVATFTYLAEDAPKYVTGHAINLGAIGLSLLLTLANIAYVRWENNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCE8</accession>
    <name>A0A9Q8LCE8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_08400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759312.1">
        <property type="nucleotide sequence ID" value="XM_047907548.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71988278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08400"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="655"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1231"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1259"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1286"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="12">
        <location>
            <begin position="563"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="713"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1322"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1322"/>
            <end position="1337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1407" mass="157461" checksum="F7D98C3C84310620" modified="2023-09-13" version="1">MALVDYDRSLEHRIDHRQKARLQQRRVEASQRRGPEQRSTVPTHQTAVPLFRHILVAQNCCAPPLLAPLVTSSSRGSNWAKVRVGRVAWRNRRRSKPNATMSSNQNRRDPAPTGERTPQRRRQSSGRPSSSSRHRPASSGEHTSDPHRPRRNSSARRERDESGRNPRHLHSHAAQRTRRRSSSHRTPGVASRLERPLDDKSGGGYSTRPEVRVTQLPLSADGYGDSATSPYTPSANDRDPMLEAGRNADLNRKKSLVRPERRRNDPDEPDYYYRKHAQNMNVMPSTTGRDPQVEDDLQTLSSDATKHGSDPLQEKANLERGKSIATRSGSKKHPNKLSRKATQQVREDEEKERRKQKIQEASGTPSLWSTYCHVITFWCPNVILACFGKKQKEQQRAWREKIGLISVIAFIMTFVGYLTFGFTQTVCPQGGPLRLRINNVGDGYMIFHGKAYDLTRSQHPLARGVPENSNVLFDPDPPGKGMDGSFMFQNVNGACKGLITAQPNSDVVTDNNGDLAWYFPCNMFAQDGSTQPNMSIPYYLGYACHTSRNARDAFYGLRSSGDVFFTWDDIRNQSRNLMVYSGDVLDLDLLRWFNQSQVAYPSKFDQIWENTAVKGKDVTLAFSSGQDKQIAQCFQEIIKVGSIDTETVGCIASKVVLYVSLIFILGIVLIKFVLALAFQWFLCRKYAAPKTSMTKDKKKRQQQIEEWSDDIYRAPPKITDPASVSGSGSDRTSKRGSFLPTTSRFTSPYAIERTMNKDRAPPTTMVSQHSSAKLNPAAMYGHTNRSEATLQAMGNESRASLMDSHNFGSHRYSSGMHPETDASGPQGFIHESVVPQPPPEWQPFGFPLAHTICLVTAYSEGPDGIRTTLDSIAMTDYPNSHKLIYMVCDGLVKGAGEKLTTPEACVSMMKDFSIAPEEVQPFSYVAVASGSKRHNMAKVYCGFYDYGPDSIIPLEKQQRVPMITVVKCGSPAEANAAKPGNRGKRDSQIILMSFLQKVMFDERMTELEYEMFNGIWKLTGISPDFYEIVLMVDADTKVFPDSLTHMVSAMVKDPEIMGLCGETKIANKTASWVSMIQVFEYFISHHSSKAFESVFGGVTCLPGCFCMYRIKTPKGGQNYWVPILANPDIVEHYSENVVDTLHKKNLLLLGEDRYLSSLMLKTFPKRKQMFIPQAVCKTTVPDTFKVLLSQRRRWINSTVHNLMELILVRDLCGTFCFSMQFVLFIELVGTLVLPAAIAFTIYVIALGIKAAITNTAAPVIPLILLALILGLPGVLIVVTAHRVSYVAWMFIYLLSLPVWNFVLPIYAFWHFDDFSWGDTRKADGEKKGADKGGHGGEGEFDSSKITMKRWHDFEQERRLKGPQWGGNVSYGSYGPGAGGYGSPQQTDASTVGVYGVGHERKPSSLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCM4</accession>
    <name>A0A9Q8LCM4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759358.1">
        <property type="nucleotide sequence ID" value="XM_047907632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCM4"/>
    <dbReference type="GeneID" id="71988362"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08484"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="304" mass="33224" checksum="5AB911C84C2C60EB" modified="2023-09-13" version="1">MWPPALFVTSHSQVTMGAAPSNPVPVLPARYLFSFGDSYTATGFDISGAQPSLSNPLGNPPYPHTTTSGGDNWVDIVVYNSTRKDTVAYNYAVGANFVNMTAAQGQAYAPSGPVKELKDQMDQFRQLPKTILWNATNSVFFNFFGVNDIAVQVFSGRSYDNATKILAPDMSNYFTQIGQQYSLGARRFVVVLVPPIWRASVFDYGRATTAATVRNLTTIWNNAIQSSATSFPSRYPGAKMVIFDPTATFNQILDQPQQYGAPNNTCYSYPAGQPCLWADFIHPGLVVQKALGNAMNTFLKSNGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LE48</accession>
    <name>A0A9Q8LE48_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        </source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHE8</accession>
    <name>A0A9Q8LHE8_PASFU</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
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            </authorList>
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        </citation>
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        <text evidence="3">Belongs to the epsin family.</text>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        </source>
    </evidence>
    <sequence length="550" mass="61171" checksum="05CA3ECF73148246" modified="2023-09-13" version="1">MSSVLRSVKNVTKGYSSVQVKVRNATSNDPWGPTGTDMADIAKITYNSSTDFYEVMDMLDKRLNDKGKNWRHVLKSLKVLDYCLHEGSELVVTWARKNIYIIKTLREFMHTDEDGRDVGASIRASAKELTSLILDEERLRAERQNRGSWKSRVTGLEDFGLGGEPNQEQRRHQQRRNQRPDDDDDLEFRLALEASKNEADEAAKRQKPQNGEADDDLAKAIKLSQEEEELRKRQLQDQEQGDLLFDDTPAQQPQPTGFNQGYQQQAAVDWFGNPVQGQPTGYYDNAYSQPTGLQPQQTAFQNGYGYQQPQQTGYDQMQQPQQQFLQPQQTYNPWAHQMALDQQNQNQQQALQQQQTAQAGSNNPFGGFGQSQGTIGVQATGSNNPFAQQAPRAQTASPFGGKPTLDTLREQHATNQFTQSRPNPIQNFTSPVQQQPVQPQQTQQQQPPQDPYQAKLNALLASGEGQDTFGNTGDLRIPSQHTAPGTFVNSAGAGSMGRLEAAKTGNNPFYSQAPQQYPAQTGPAGGFGGNNPFGARPPQQQNNQGSLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHK2</accession>
    <name>A0A9Q8LHK2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein klf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761950.1">
        <property type="nucleotide sequence ID" value="XM_047905294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHK2"/>
    <dbReference type="GeneID" id="71986024"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06146"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO17584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="849" mass="95293" checksum="F67D8E2FA196FCA7" modified="2023-09-13" version="1">MDQSPVEPSPKRRRASRAGQVKRFECQHTGCGKRYSRAEHLHRHELNHRPKEIYACELPDCGQTFVRYDLFARHKARHGSTTDQPPRTQQVAQQEPPSTADSPSEDISAPELQLTQQDNVSVGAGRVVGHVPAQENISQVPSTWMQPIHTLSSTAIPPSPARPAGRTTPLPLTRNWTTDDAHAQANDSFAAWLFASPGSQNTEFDLTNLPFVDFGLEYSPQDIWQFHQQSDPGQHLGVEGLQNQAPEDVAVSEASHRFGASITEDRRNEVIELIAAYQRRLQVTKLQDRDHLLYMDASSQLSNMSSAVLDKLVAAYWLASRQIPVLHQPTFCSNTCHIMLLLAVIAFAATDMAKSQPKSALADHRELGDLVINNLRWEVFTHDDAHPPIQLWVAQTLVIIEYYEKHCSSRKLHERGHIHHSSTLTLLRRGSPLVGTSETDGPSEVPTRQVSPALDGDKTFGVQHRSGIDAWWLQWVRNESFKRVVFAAFQMDTLHAVMFGHAADMAPYEIRLALPCDESLWAATSAEEIHRLDANLKMYGIRPINFLDALKKCLHAHDVQTHAPARVLLMAGLLNVGWHISRREKHLQFLETVPSVREQGRWRALLLHAFGQWRSCFVEAVGGRNNSINQLDMHGSSPGVLYYLAHMTMHADIIDCQIFSGSKRLLGRKVSEKDYLNVVQRMQSWVCTPLAQHATLHAFKLLHETLLQSNILHSSQTSRLGSTSVKYNCRTDPLFYRPWALFLAGLIMWAYQHASSTYPVIAAREQRQVAGIDDDAICCRYLSICATIEDPAHIIPSLSSHGCAAVLAVLSRILSNAEPEILDEASKRLQECRDMLVSNSVSWPVLSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI50</accession>
    <name>A0A9Q8LI50_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762197.1">
        <property type="nucleotide sequence ID" value="XM_047904926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI50"/>
    <dbReference type="GeneID" id="71985656"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05778"/>
    <dbReference type="OMA" id="KWQSAGK"/>
    <dbReference type="OrthoDB" id="10509072at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="24626" checksum="E2ED3F1941ED1AA2" modified="2023-09-13" version="1">MARTHYSDERYESDDSSLADSPRSRHRRRAHSEESPYTERPRARPRHARRHSSYASEKTRSKWQSAGKVALGVAFVGIVAQVVNRWVEKREIESIRREEDRVREKRRQFEKAKAKRRREEDRREREREDRSRGHGPEVWEVTEEVRRIGYLPAEERGRSESRAPRRLEAPPSREASIDEWEEDQVNHHERRGRAERSRSRPAVDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIT3</accession>
    <name>A0A9Q8LIT3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Decarboxylase NovR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762526.1">
        <property type="nucleotide sequence ID" value="XM_047904768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIT3"/>
    <dbReference type="GeneID" id="71985498"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05620"/>
    <dbReference type="OMA" id="YYDEQLA"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="2">
        <location>
            <begin position="50"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="285" mass="31542" checksum="293BCF9F4C713A19" modified="2023-09-13" version="1">MAPSATVTLSEPKSNASVGALGRTKDGRPLKIRSYPKFISLEEERLYRKQHLAAAYRVFADRGYDEGVAGHISVRDPILTDHFWLNPLSMHFSQISVSDLILVNEEGEVVIGDEPINAAAFAIHSEIHKARPDVHAACHAHSVYGKAFSVFGRELDMITQDSLRFYKDHAVYPQFGGVVLDREEGRRIAEHLGGGKAIILQNHGLLTVGETVDAAAFWFVSLDKTCHAQLLVDAAAQGSGHKKTFIHDEEARDSYDQVGKPEKGWLAFQPYYDDILAKTNGSFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ35</accession>
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        </submittedName>
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        <name evidence="7" type="ORF">CLAFUR5_06850</name>
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    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_06850"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GENERAL AMINO ACID PERMEASE AGP3"/>
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    </dbReference>
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    </dbReference>
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            <end position="161"/>
        </location>
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        </location>
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            <end position="221"/>
        </location>
    </feature>
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            <end position="252"/>
        </location>
    </feature>
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        <location>
            <begin position="124"/>
            <end position="255"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="286" mass="31329" checksum="2C499F31F55D54B2" modified="2023-09-13" version="1">MTDATAKEIASIVASPSSPEAENQPTLTRNGNILNDGLQRGLKHRHLVMISFGGVRARWRPDLLLIIDVDVFFVTQCLGEMTTLFPVKGAFLELAGPFVAASWTSRWRLAWGGIVVDELCPLRCVQGRAPKFFAKTTSNGTPVNALVLSNVLALVSMLNYKAGPGKVFTYLFNISGSATFIAWAAQGNAVEAIPFRAILYPFGTYSVTFMNKFLVFIAGYGDFVSGFQPVKSVVDYVVIAVFVALFVFWKVFKKTAVVPLEQVDLVTGSRYALLLTSWACYLTSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ75</accession>
    <name>A0A9Q8LJ75_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71985299"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="27"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="27631" checksum="3F6297A5D070D040" modified="2023-09-13" version="1">MNFDIVSTAVRPLSGCVKSLFTDSRWSDLEIRCGDRSWAVHKIVVCSQCEFFATACDRNSKEATKDVITLQGDLPDAVHALIHFLYTGDYDGCDWLEEDDWMPLVFNVHVYSTAKKGGLDRLAGVAARIFKDRAGNELYEAAFTDAIEELHRHPEADNLLELRKYSVMIAALNGASLYEETSGGGRFWEVARAVPQFAADVLKSVLEEALREKKDEARKKEERCERCKVCLHCCECEEEYDEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2J7</accession>
    <name>A0A9Q8P2J7_PASFU</name>
    <protein>
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    <organism evidence="3 4">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO10829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="20278" checksum="5D6F51374B4373B1" modified="2023-09-13" version="1">MCSYKAMEECRKKGKAKAIGVSNFSKAELERIIKETGTVPAVHQIECHPWLQQAGFDAWHKEKGIHITQYSPFGNQNAIYTKGESLGKLIEDPTLNEIGKKYNKSGAQVALAWGIAHGKSCRSVIPKSKTENRIKQNLEGDFKLEAEDVKKIDSLDKKMRFNDPSGNFGWDFYKDLDGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2L3</accession>
    <name>A0A9Q8P2L3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P408</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P408"/>
    <dbReference type="GeneID" id="71980199"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00321"/>
    <dbReference type="OMA" id="IDIFGCA"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="355" mass="38974" checksum="1778BB5A0B9DE086" modified="2023-09-13" version="1">MASNIIDKTKHALHFNKEGDIKIAGRKVHGTGYGLMGLTWRPQPPSQEQAFTAMKTALDSGANFWNGGELYGTPERNSLHLLKEYFDEHPSHASKVVISIKGGLVKGGMKPDGSAENTRRSIDECLNVMTNKKLDIWEAARCDPETPIEITMRAANEYVKAGKLGGISLSECSEDTIRRAAKEVTVSAVEVEFSLWSTEILENGVAKACAELDIPIVAYSPLGRGFLTGEIKKLEDIPEGDFRRTIPRFYPENFDKNLELVTQIEELAKRKGCKPGQIGLAWVRAQSKKPGMPTIIPIPGASSPERVRENMVEIDLSENDVKEIDSLLASVEVIGGRYNEHGAALTFGSTPPLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P409</accession>
    <name>A0A9Q8P409_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipid droplet phospholipase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_01570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756697.1">
        <property type="nucleotide sequence ID" value="XM_047900718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P409"/>
    <dbReference type="GeneID" id="71981448"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01570"/>
    <dbReference type="OMA" id="FCTPHVG"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="5">
        <location>
            <begin position="9"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="342"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO12331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="50093" checksum="F708BC1F054F5E65" modified="2023-09-13" version="1">MAAAQQNASADHLAVICHGLWGNPSHLNHLRDTLRAAYSDQSLHILVPTSNSDNQTYDGVEVGGERIANEIEQRLSELEQQGHKIKKISITGYSLGGLVARYAIGLMYSSGLFDRIQPINFTTFATPHIGVRTPRLGARSYFFNFMGARTLSTSGQQLFLIDSFRDTGRPLLSLMADPNSVFTAGLRRFKHKWLYANTMNDRSVPYYTAMFSRTDAYVDLDKVEVHYAKGQPKPGNVILDPENPVTPKQPSGEQLSLVQRLMPHQRTINNIPFYMVIFSLLPLALPVFLANAGYQTYQSAQRIRHHESGKAFSLDRYRVKLLEEAQAVQDRVYERVVEQQAEDYLPTPPPESQSVDSASSHTKEDLELSRRETTREKGPSPLLVLTEGQFDMIENLDNLGFTKYPVHIQKVRHTHAAIVVRIQKESFAEGRVVVQHWIDKFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P474</accession>
    <name>A0A9Q8P474_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pal1 cell morphology protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_00342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756920.1">
        <property type="nucleotide sequence ID" value="XM_047899490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P474"/>
    <dbReference type="GeneID" id="71980220"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00342"/>
    <dbReference type="OMA" id="GPSMIHH"/>
    <dbReference type="OrthoDB" id="5352132at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF2">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57063" checksum="641D71B9ABDA624D" modified="2023-09-13" version="1">MAFAGATAPGIERQRSPVGLTLNLSSNNPFRNRTTSPSPHNSPFSESPSKQLRPMSRNPFLDTSEYNTAPDRADGVLNGRSNNAHPIPEDIFNELSLLDKPMTNQAPRGAPPRSGPIPPQTQRPLGLEQRRAPPRPSRGPDSPGKRDPRAPMQLQRRASESSVMEKDRRPRVDRDRADRSERTESEERRRRERRKEREERHRREKEKTRTGDKKTRKPQGLDLIDKLDVTGIYGQGLFHHDGPFDACNPHRNAKKDRKAPMQAFPADSANMQLGGAGPLRSRLDLDKFHGRGEEGFTEFATTRKAAPAATIIDPKGAEYVHGPESNGLGTSTFLDGAPASKSALQRRDSEDPELNGFGTSGGLSRKKSLAHRFRGMSNSRRPAPGDIRSPDARYGSGSNDLESPAPSYPIKAISAGGPPRARYNKENEINPFENDYEAAFEKKGTQIRIAEQEGPSAGRPRAPSSPKQHLGLSRSLTSDNGAALKGRSSSGEEERPSGGFLNRMRSLKGGPRRQRNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P587</accession>
    <name>A0A9Q8P587_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758119.1">
        <property type="nucleotide sequence ID" value="XM_047902979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P587"/>
    <dbReference type="GeneID" id="71983709"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03831"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="19696" checksum="54A1CE9DA254DF5C" modified="2023-09-13" version="1">MATTKKHRSSRRARLHPDEDVIPLHALPKELPPTTTFHRDAFPVSIMLAIVNPRSLLIKSCDLSRSQRTAVEKRPTLVCETSTTIFISVAQSFDDILDQLATHAQTSFGINLSDRSRWGCVMLACCEDTSEMVDKDNAAFFISAASQGGWGWKFYVAELERSPRGIWESRTSIRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P599</accession>
    <name>A0A9Q8P599_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758075.1">
        <property type="nucleotide sequence ID" value="XM_047902474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P599"/>
    <dbReference type="GeneID" id="71983204"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03326"/>
    <dbReference type="OMA" id="ARSDFAN"/>
    <dbReference type="OrthoDB" id="343582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000016">
        <property type="entry name" value="mRNA cleavage factor complex component Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054127">
        <property type="entry name" value="Pcf11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021605">
        <property type="entry name" value="Pcf11_Clp1-ID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21936">
        <property type="entry name" value="Pcf11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11526">
        <property type="entry name" value="Pfc11_Clp1_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="15"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="681" mass="73901" checksum="6173B0F8ACEF83E3" modified="2023-09-13" version="1">MSSRSPRGSLSGASSSAEVAADFEDALKDLQGNNRYEISNLTIIAKENTEHAQAISKVLENHIKTTPASRKLPAFYVLDSIVKNVGTPYTVYLGRDLYRTFMDAYTLVDGTTRKAMEGLTKTWKEPVPGSIDPRPVFPLETVRPIDNALIKARTAVLQSRQPQVPYRGNMPTPPQHNGQFSTPPHPLPPQPYQAYGQPQPQQQQHTYQPPPQQQIQPASHDVEGVKRDIQALIPRFQQMLASNPGEGRFQAQLGALQQLLNLLQNRALSPPEFQAVRNQVTILSSQIPTQQPARPPPQAAAPTPQWQQPAAAPFAPPYQPPQQPQYPNAQFPLPLPAQVPPQGTAAPPVMPPSALSNLQALLANVQKPSTPQMRAAIPEIRNATHSQLHTVQNHTAAAPSANGPVDLLAALSKAGIINTAHPASTPIPHAPPPATAPPNLDFLKSLQSILPPVQGGAPMQMPNVPPVQTITAASLKVHRPELIHALYDAQPNQCTQCGRRFLATEEGREKKQRHLDWHFRTNQRIADPNTNRGHHRNWYVDEMEWIKHTEFDLSTTTATAQDAAAAAKIKDDPSQKSVRAPAGMTKNTCNICQEDMHSQYSDELQDWVFANAAVQNGRIVHATCLAEMTKPALGGSSAGSLAAALASVGGGGCRERSATPDSLKRKAETAMDGGGARLKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5E6</accession>
    <name>A0A9Q8P5E6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial-processing peptidase subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alpha-MPP</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Inactive zinc metalloprotease alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Matrix processing peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_02704</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758182.1">
        <property type="nucleotide sequence ID" value="XM_047901852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5E6"/>
    <dbReference type="GeneID" id="71982582"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02704"/>
    <dbReference type="OrthoDB" id="277191at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000023">
        <property type="entry name" value="Mitochondrial processing peptidase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000032">
        <property type="entry name" value="Mitochondrial processing peptidase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="12">
        <location>
            <begin position="50"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="206"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="247"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00083075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO13816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="565" mass="61972" checksum="E81A3D6544179203" modified="2023-09-13" version="1">MMSKTLSLPRQLTKGAKAVARARQYATASNHAQDPTDLDTITTLPNGLRIATAEQAGHFSGVGVYIDAGSRYESNALRGTSHIIDRLAFKSTTKRSADQMLEAMEQMGGNIQCASSRESLMYQAATFNAAVPDTVAMLAETIRDPNITDEEVFRQLETADYEIGEIWGKPELILPELVHMAAYKDNTLGNPLLCPKDRLDQIDSRTIEAYRKAFFKPERTVVAFAGVNHQEAVRLTEQYFGDMKDPAASIARPSTSSEAQQVQPPYPTSQLPPQKDSGLMSRLFSKNLSTSASQSATVSPLDPSDIIPHPLDQPINYDQPSHYTGGFLTLPPLEIPPNPALPRVSHIHLAFESLPISSPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTNVLNQYGWVENCVAFNHAYTDSGLFGISASCATQFVPRMLDTMARELSLLSTETGLGRLSEIEVKRAKNQLRSSLLMNLESRMVELEDLGRQVQVHGRRIPVKEMVANIENVTMSDLRRVAKQVFSGQVHNVGNGSGAPTVVLQQGEEENVKLKEIPWSDIQERIAKWGLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8P1</accession>
    <name>A0A9Q8P8P1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761467.1">
        <property type="nucleotide sequence ID" value="XM_047903578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8P1"/>
    <dbReference type="GeneID" id="71984308"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04430"/>
    <dbReference type="OMA" id="MQSKPYA"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050152">
        <property type="term" value="F:omega-amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000002">
        <property type="entry name" value="Nitrilase family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF30">
        <property type="entry name" value="OMEGA-AMIDASE NIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="297" mass="32929" checksum="A570B2384F7101EE" modified="2023-09-13" version="1">MAKLLKKPLKLALVQLATGKDKAANLARARSKVLEATSKGANIVVLPECFNSPYGTNYFAQYAETLLPSPPTKEQSPSFHALSELAKEAKAYLVGGSIPEYWEESKKHYNTSLVFDPSGKLLDSHRKVHLFDIDIPGKISFHESEVLSPGNKVTIIDLPEYGKIAVAICYDIRFPELAMIAARKDAFLLLYPGAFNLTTGAMHWELQARARAMDNEVYVGLCSPARDMDADYNAWGHSMLVNPNASIQSELDEHEGIAYADLDGDTLAETRKNIPIYGQRRFDVYPDVSAGKVKYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8P9</accession>
    <name>A0A9Q8P8P9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beige 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761603.1">
        <property type="nucleotide sequence ID" value="XM_047905532.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71986262"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06384"/>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01201">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1540.10:FF:000002">
        <property type="entry name" value="WD repeat and FYVE domain containing 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056252">
        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23295">
        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="7">
        <location>
            <begin position="1697"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="6">
        <location>
            <begin position="1868"/>
            <end position="2163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2248"/>
            <end position="2288"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2295"/>
            <end position="2336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1125"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1626"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1524"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1647"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1673"/>
            <end position="1683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2488" mass="279152" checksum="FA28EEB679876F29" modified="2023-09-13" version="1">MALRAGQPASRMSSFSRGMNADEQSSDTASLIQQLGLLQSTSDVDELSRLSDTAERLRHDLGSSSNASAKDTFRHGHGFEKTLQVLHELGTNPIAPMRNLLQLLTAALRHRGNDRYFSNHLHGWDSLGKIFNAFDSQEHVSSLLEGLLALAVDEIGDTASDPRHRTIVHARACECATRVVLGHKQPVEWLESLAALSETSTRNASALSRTNIAHDILHYLDTAAQDDTLRPTCTRLLLSVARYGLQSLDDVVGLFKSAAASDTAKETLLTLLRSSKEPAFIQFDLSLCGYSSIEFPRLPGAFPPSIGYSLTVWLKIDEFDPNAHTTIFGAFDANQGCFVMMYLEKDSHQLILQTSMRAPSPSIRFKSTHFEASTWYHIAIVQRKSPTEPNQSMASLFVDGNFAEQRKCHYPETPDESLERSNSQSASMPAAQRRFKPVQAFFGTPRSVASKPRPNEVTTKYSLGGSHLYQVPLTDEFVAVHHRLGPRYSGNFQDTLGPLLTYRASSELNRYNETLHPDRSDRSDIMIATEGRGSEVVPESRMLLGLSPSAHIDFDAPNINFGGHDVELDHKAQQKYQILAKQVRAVAVNTAVATLNEAVTRSYGTGLVMGDPVIVTSRPLDDATWRLCGSIPILLQQLESATSKKSFLQAVEILVECVRDNWRISEAMEKGNGFGMLALIIREKLGFEVASTPHASTRRPSPMIGFEDRQSLPAELLETILDFVGHSKSNPGESLLINPMAYRVLVVDFDTWRRCDLASQTIYWKQFVDFTSGNRHSAFNDKRLTKMRVVKRLIEALKSEDVTAESAPLMMTAMKALLDTTAAQSLYRDLAMFVAYSLQDNRAMHAMGVKSFASTVSLRQKMGSWARNGRGSRPSTPGGAPTSITKPALTQYEIAILTLKLVLEILGEERSSINAKRFNKAIPTRWLLHLFAETDVRVIELTLSLTCRALIALGSEFKINFADKNSGFTILKLRLKPFWRTTSIWMLSFAMLFGRNVPLDWLSQDFSAFHLVEMLSVDDSLAICHPEMLPVIFTMLEAGMRKVAKDEEKQDELEAHILKTVIQLLGELYDRSSAFRDFTITSKYLQELLFVLFPLLTGTDRLSAETELGSGSDALSFRGQQVRMRPHSNSLGERPPSVRSISPAKGRRTPSPMAANRVQVPRRISSFVLINDGGDRLAVPPAQFKAPMAPKSGGNLKINVTNSLVESLLELTITLFIDQICYRDKFSGIGLFLKVPPGFKEHQAYFESYVLVNALSQLGSHLRLNQRLLVETRVLTNLARYAQHMAEAVSEGWFIDGAQPLLDFTGEILEHLQAPDVASQKAVRLCSQSITMIRVVFLKATLWRLSELNEDANQKHVDEFLTKMTYWQTILFSAENQETLFTKLICYLLYHKLVSGVKSVRLAAARLWRTVLVQKPTETATMLTATMGPDQRHLSTGFMKLISMDDEDFLAWVDQTRSVLDNLFHKSLSKPWDDFVQSENRSAEDTTKHRLSKRRDKLKQWHNEESAADEVINKYETSTSHWRANVHAQERVKLQRALQDQQENVNHLYAAFSKIAVLLHQPCGLLPIEPSRWHLDETEAVNRMRLRIVPDTTEIKQEYQPKRKASRSVSNGAKLAIDTQISRNSDGTSFPMLAAPNTTHLDGANESVEQGTSGRPRSESVSNSQLLEGGFEMVDDPKEDEDGVVEDKNRKIMTSLQRNDQVQQLYNTSRIVGLEACEGLVVVGQKCFYMQDNFFQRSDGEIISVAQAPADERDPYVQLISGKDVGSSKTKHSIGDQETRHWTWAEVLSVSKRRFLLRDVAIEVFFTDGRSYLLTCMSSKVRDDLYSAIVQRAPHVHSTFGLASEDAWRLDTLRNPEEAPKNLGSKFNSLFNNGPANTAMKRWQRGEMSNFQYLMLINTMAGRTFNDLTQYPVFPWVLSDYSSEELDLDDSKSYRDFAKPMGCQSPMREAEYKDRYKQFAEMGDHNAPAFHYGTHYSSAMIVSSYLIRLQPFVQSYLLLQGGAFDHADRLFDSIEKAWLSASKDTMSDVRELTPEFFYLPEFLTNINKYDFGTKQVTGEAVNDVRLPQWAKGDPHIFIAKHRQALESPYVSEHLHDWIDLVFGFKQRGEAAIEATNVFQHLSYGGARDLDKIEDQVERLATIGIIHSFGQTPHQVFQKPHLWRELDKQADQRLDTLAETLTKLPDTVLNISEKVVDFTFSPTQNRLLTSGPCQLNVLPDCDRFMQWGFADHSVRFFSKHSKRLLGLHENSHVGPVTAATFVDSKTLITAGQDSTIGVWKVLTSRDLIELHPKTYLFGHRTAVTVLAASRVFSTLVSASADGQTLIWGLNRYNCIRILLSPGGPAIQAARISNSSGHILLCRGSKALLYTINGQLLVEQQLCDRDEDDILSCAFYEGANEYLERELIFTGHANGLTNIWTLTALSDGKWCLLLVKRMSHGDHFSAKNRSAPGITAVLPVAKAVYTGDEEGNVFSWETVVRHSGVSMRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8X0</accession>
    <name>A0A9Q8P8X0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Endonuclease</fullName>
            <ecNumber evidence="17">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_05677</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="17"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762020.1">
        <property type="nucleotide sequence ID" value="XM_047904825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8X0"/>
    <dbReference type="GeneID" id="71985555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05677"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000004">
        <property type="entry name" value="Nuclease 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="20">
        <location>
            <begin position="94"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="19">
        <location>
            <begin position="95"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO17654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="38661" checksum="B56A282837DD4462" modified="2023-09-13" version="1">MPPPSANMSKVTIAIVAGASAAVGAATTAALFGIGRSKEQTSTITASAASPTRTGPAPPVPITRDDPKPPFIPPVDPAGVFQYGFPGPVSDIRQAPSLTSSYNRITRNPHWVAEHITPASLLMQGGDRRHSAFAEDESIPEMFRAKLKDYFRSGYDRGHQVPAADAKWSQKAMDSTFALSNMCPQVGEGFNRDYWAHFEDFCRRLTSFYPSVRIVTGPLYLPKRDPIDQKWKVTYEVVGHPPNVAVPTHFYKIIYAEDGKVGGKVSLGAFVLPNDKIPNDKPLKDFEVPVEALERASGLEFTKLLEPARKKKLCQEINCSLIIKEYAERQRTFMTNPPAKGQLPPSPSPAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8Z0</accession>
    <name>A0A9Q8P8Z0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8Z0"/>
    <dbReference type="GeneID" id="71985528"/>
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    <dbReference type="OrthoDB" id="410198at2759"/>
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    </dbReference>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
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    </dbReference>
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        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="259" mass="29607" checksum="B2DE2AA9588DA0FF" modified="2023-09-13" version="1">MISSDEECTHRNTTARHSSKMTLKLLPLPQNEWQMYTRICKAAFIPGILSVMYPEGYSDEAQEHALGTLLRTAERHPDRIQMMKVVDEALPDDDLYQKVVGISQWKIFPRERTEEEMKQEEEVSNREDKECGSPPGLSEAVADDFGGATSEYKKKHLGNRPHVLLHILATRPEHERRGVGAMSLAWGTQKADEMGLPMYLEGGPKGVALYKKWGFEVVDVLPWDAQKHGYHDSLKHLCMLRPARKSSWSRSHHTQTWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P931</accession>
    <name>A0A9Q8P931_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762094.1">
        <property type="nucleotide sequence ID" value="XM_047905505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P931"/>
    <dbReference type="GeneID" id="71986235"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06357"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="25472" checksum="4A6362565A9ABEE7" modified="2023-09-13" version="1">MDSSEVKIDAAQLMAALRDHAASLEILSIRTRRRLRPALERHEILTGLDGLHKISGLELDSDSLTGTESWPSCNIPALPPAMTALRVNTYSSLTELPWILSALATRLTPLMKILEVTFPLQKNDNAQYVESIKEADMDNEKWRIRPDRDWIILVSAFPVAGRFNIKFMCWNTDRSISTVIGGLVSRFNGISVGDLIEEFYSDWEIHEDSEIHMIRDTIEAIFSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P975</accession>
    <name>A0A9Q8P975_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762022.1">
        <property type="nucleotide sequence ID" value="XM_047904823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P975"/>
    <dbReference type="GeneID" id="71985553"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05675"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="94" mass="10514" checksum="7A6F4C27DD0324F0" modified="2023-09-13" version="1">MTLCFDAAYHALKTSKITEAEYLHQVLAHFSGVRHPADDKARPWELKINDPVGNAIREAALSSPSTRPESIFRLEELFASTLRDGVRAVHTLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9R0</accession>
    <name>A0A9Q8P9R0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent monooxygenase OpS4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762921.1">
        <property type="nucleotide sequence ID" value="XM_047906438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9R0"/>
    <dbReference type="GeneID" id="71987168"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07290"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="249" mass="27496" checksum="5002E293A0737BFA" modified="2023-09-13" version="1">MPLDIIVVGAGIAGLSAAIGLARTGHNVTVHERRDSTKREDSGSGIQIQPNVVQILDDWGLMPEIRKVAHDPELVDLRTYNEGSVAKQDYRPLGPAPFGLRRVLKDIFRDHAIQQSVKICEGQGIDHVDVDHHAIILSDGRTVTAGLVLGADGSNSRVRKTLFPDSKPTVLEQCAFQVLVPLNKVQQDPEMREILDEQHVIIISSPGRSVFASPAPYHDLMVIQFVDHEYPLEGDPHPDQHNMKIKDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA87</accession>
    <name>A0A9Q8PA87_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Forkhead protein sep1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763136.1">
        <property type="nucleotide sequence ID" value="XM_047906541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA87"/>
    <dbReference type="GeneID" id="71987271"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07393"/>
    <dbReference type="OMA" id="PNDAGWQ"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000260">
        <property type="entry name" value="Forkhead transcription factor (Sep1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="204"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="4">
        <location>
            <begin position="204"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="754"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="790" mass="86013" checksum="C5A4467B339D9EBC" modified="2023-09-13" version="1">MATTRRNASLQVFEDPPDAYNTNSNSDDVETALLNALRPLSDASNKQNVQLNPSTTTKPGSSPSKKDSSPARPTSAHSLKEYRFTPPPQPNFTTDSIQKNGDFYSMYHQVAPQPEHPLYPQQHPYQSYDKENYFETGSSFGDLSVPSYPDVDYGYKTSLKRSFTNSSAVKVPSQSLKKQKLETGEPFDLPNPEDLPHPTDDGSKPAHSYAELIGMAILRAPNRRLTLAQIYAWISDNFAFYSKNEGGWQNSIRHNLSLNKNFVKQERPKDDPGKGNYWAIKPGEERPFLLGKKQPLRKIINPDGSQYVHGLPMPPSDPVSYRAASTPAVSNFTLGPNPVRKLETKDIDSAKFPDDAELSSDGTIPASDPALQEDEPEKDDSAAMPPPPVLMRSSPPPQDLGSSPPAMHRNDTPPPAPRFPPSSRSGGQRRKFAGLNDSGYWSSIESSAARGAANQLASESDLRSHRIKKGRAEAEIARMRSSSFDSPTKDGSRYLALPSAFGSSPVRKDDNPLTPAVVFKRPAKPAPAISPNTNLRDHRKAVRQLLGSPAKTYSPMPAQTWSPAFNLQDSTPAGLTPFISPYKQGTTPWPAVEDSSVSYNLNNAAFDVFLDIPDQDIAARGSPEKRSNGRPSLARAATSTGILADITGTAKSNNLMLPPATGSPFSFSPFLTKSGALRSPAKLDSPLKQSHKPPPISQPTDDFNWPDLTAGGENAPLYIDNNNDVSDLFGVQLHSDGSEEGIDIFQDFGKIGQASQTFPAPDRSTGSPVKRTSMGPPARPAMHRSSTSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAJ8</accession>
    <name>A0A9Q8PAJ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763288.1">
        <property type="nucleotide sequence ID" value="XM_047906630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAJ8"/>
    <dbReference type="GeneID" id="71987360"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07482"/>
    <dbReference type="OMA" id="ICMLDHH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="4"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="244"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO18922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="289" mass="30966" checksum="F8C7DBA0E610BB0A" modified="2023-09-13" version="1">MSGYDRALSVFSPDGHVFQVEYALEAVKRGTCAVAVKGSHPEESVVVLGCEKRSALKLQDTRITPSKISMVDNHVCLAFAGLNADARILVDKARLEAQSHRLTVEDPVSIEYITKYVAGVQQRYTQSGGVRPFGISTLIVGYDPGSKEPRLYQTEPSGIYTAWKANAIGRSSKTVREFLERNHKDSMTRAETIELTIKSLLEVVQTGAKNIEIAIMAPGKNVEMLPSDDIEKIVEKINTEKDAAAEANANRRGGARAGGAAAGDAAASAQGPEQVLASRPAGEGSGPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAM0</accession>
    <name>A0A9Q8PAM0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_06823</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763282.1">
        <property type="nucleotide sequence ID" value="XM_047905971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAM0"/>
    <dbReference type="GeneID" id="71986701"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06823"/>
    <dbReference type="OMA" id="ITYCKTR"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000005">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000241">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="326"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO18916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="734" mass="81512" checksum="19A22E54F3A63F42" modified="2023-09-13" version="1">MDRQSVYTLSLFGESQGNGEESVKQQEKEIVKFVLEFHLDGVYIYRDQIRENVLSKQYYCDIDIEHLIAFNADLADRLNNEPADVIPIFERALKTCTQRILYPSRSAEDLDLAKALPEHQLLVHSSVSQTSIRGLTATNVSHLVRIPGIVIGASTLSSKATKLHIQCRNCQHEDNIAVTSGFTGVTLPRTCSRQKDPNDGSEKCPLDPYFVVHEKSQFIDQQVLKLQEAPDDVPVGELPRHILVSADRYLANRVVPGSRCVIMGVFSIYASQKNSKNKGAVAIRNPYLRAIGLQTDLSHNQAGGMGIQFSEEEEQEFLDMSRRPDIYTVFADCVAPSIYGNNDIKKAITCLLMGGSKKILPDNMKLRGDINVLLLGDPGTAKSQLLKFVEKCSPIAVYTSGKGSSAAGLTASVQRDTNTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPIFGRYDDLKTPGENIDFQTTILSRFDLIFIVRDDHDRNRDETIAKHVMGIHMGGQGVQETVHAEIPVEKMKRYISYAKSRCAPRLSAEAAEKLSSHFVSIRRQVARAEQDANQRSSIPITVRQLESLVRIAESLAKIELQPIATEKHVDEAIRLFLGSTMDAVMSAGGDTSALGMGGNRELVEEVHKVEDELRRRLPIGYTSSLATLRREFVERKNYSEQSLNRALQVLVRRESVQLRRGGTLVHRSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBE4</accession>
    <name>A0A9Q8PBE4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Decapping nuclease</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_07365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs. Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1). Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5'-end triphosphate to release pyrophosphates. Stimulates exoribonuclease activity of Rat1, allowing it to degrade RNAs with stable secondary structure more effectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763749.1">
        <property type="nucleotide sequence ID" value="XM_047906513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBE4"/>
    <dbReference type="GeneID" id="71987243"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07365"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="8">
        <location>
            <begin position="26"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="392" mass="45300" checksum="665AB0538571A3A4" modified="2023-09-13" version="1">MSGTSRMQSFKFHDLTPFQGKSAAVKRPREITEFSFDDDHVCFPLDSRSLRYYFPPDIDVPYVRDRPRIDLSAGFTSFRKYDDAADLGLNPLLDTIQQYEEQTKTQLQADVLTWRGMMTKILVAPFDMFGEFKMLATCFEGTIYIEQDKMIKAVENEIANRRHNNGRHNNAYPAEQMQYWGYKFETLATLPRPWSECSREEIENREAETVSNYAQYCSVVRTGIGNHSIVIGGEVDAVIGCKPDEPTDPIPYVELKTSEDFHSNDQKSAKKFERKMCRFWAQSFLLGVPKIVIGFRNKDGFLQRLEAWDTLDIPNFVKRQGMQTWDGNTCINFAAAFLDFLKQQITGEGTWTIERKKGANEILLSKISDDYDKKIVGRSFRQHREDFSFDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBL6</accession>
    <name>A0A9Q8PBL6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FNT transporter (TC 1.A.16) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763880.1">
        <property type="nucleotide sequence ID" value="XM_047906829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBL6"/>
    <dbReference type="GeneID" id="71987559"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07681"/>
    <dbReference type="OMA" id="FTGAYLW"/>
    <dbReference type="OrthoDB" id="4829at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015513">
        <property type="term" value="F:high-affinity secondary active nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015707">
        <property type="term" value="P:nitrite transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="FORMATE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520:SF6">
        <property type="entry name" value="FORMATE_NITRATE FAMILY TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="283" mass="30907" checksum="6F6B8B63FB9E697E" modified="2023-09-13" version="1">MAPSTGTLPPHEAAQAVLRTGLTHLAEPLVVTFTQNLYGAMCLSSGGLFSILVRAGFAGFASENNPGIQRLLQGFAFPFGIVLTYTIGAELFTGYPMWLTMAALERKGRPHQYIYGVVTSWVGNLLGALLFSALFTYSTQAISEDPWRSAIVTQITEDIVDLSWHIIFLRAFGCGWLVTIAMFLGTQNQDGISKAVCLHFPFMISATARFPHTVEYMYLASTGMMLGAPLSVGGFFWKCLLPITLGNIIGGGLFTGAYLWWTHICGQKREYEGADGNLLDDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBP5</accession>
    <name>A0A9Q8PBP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763852.1">
        <property type="nucleotide sequence ID" value="XM_047906474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBP5"/>
    <dbReference type="GeneID" id="71987204"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07326"/>
    <dbReference type="OrthoDB" id="2317065at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="435" mass="48152" checksum="E340CEE84AB34F82" modified="2023-09-13" version="1">MAETDDHKTTLQRCSDMNEDQTRAISSSLLWATTFLACTDVSFEAAQISDDSIAESSLSTPLSECENVQDISLRLSLGYTPPTEASSQSKATLAELFAENVIAKVIRTAQAALSAVPEAFPETVAADSDGAYSLREAEFWTCGFFPGTLYLTLERLTRYPQSVTTADPRVTVRALYNELKPLCEAWSQPLHSMADRADTHDIGFIVMPALRLDWELFGHQASLDSIIRAAYSLATRYVPESRAIRSWDMLNRKDIEILDQNDNLIVIIDNTQFLEVSCGLAEYFIYRLETLPPSIERGRMVPLWDFDAPLQDNEIPLRDSSAGMIAANGMLVLAQALASIDRPALCSRYQNAAFAIVEDATAFAVAPERAYLRPGLDQAIEAAECSNAARFDAILKYGTANNNANARKRYATHGLVYGDYYFAEFGNRLLRSGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC42</accession>
    <name>A0A9Q8PC42_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transcription factor IIIB subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_10710</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764113.1">
        <property type="nucleotide sequence ID" value="XM_047909858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC42"/>
    <dbReference type="GeneID" id="71990588"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10710"/>
    <dbReference type="OMA" id="IVHEHEF"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Transcription factor TFIIB cyclin-like" evidence="11">
        <location>
            <begin position="119"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor TFIIB cyclin-like" evidence="11">
        <location>
            <begin position="226"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Brf1 TBP-binding" evidence="12">
        <location>
            <begin position="639"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="348"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="517"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="681"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="562"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="692"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="759"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="802"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="865"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="876" mass="96783" checksum="6BEE02D82DE20AC8" modified="2023-09-13" version="1">MAPTVPSRRPPGRLASLKGGPPKRRGPPKKPAAAAKNECPNCKSTELEETDGLIVCKQCYQQVGESNIVAEVTFEENAGGRATVQGGTVNDNSRHARTLNSATFRKIGGGERNSMADAQQAGKKALEAICPKLGVESNVKTQAESIWIMAAGINFSAGRRTDEVVAACLYAACRRQKENNVLLMDIAEYLKINVFRLGEVYKDLCKELYLNNESVGNQNLVELEPLIFKYCQKLQFGDKTKDVSQDALRIIKRMNRDWIVSGRHPAGLCGACIILAARMNNFQRSVREVVYVSKVADITIAKRVEEFRRTKSAGLNVTDFRNVALKIKHQHDPPSVYLDERKDKIMARRRAKREEHVRMSVARRSEGRESQPIDIQDGATDASSRLSSLVPGTPAPDAPPSAQQQAPVAQMVAPQMTPPATQETQAQSTTAEWSLGPPIPQLTPPATQESNKRKSPEHDDTPNDQNKRQRTGSEQQTAPGLPPGEVQPPLRIDADGYAIPALPVPVDAPAVVVVVEEEEPAPPPKRGRGRPKKVEPPPIDISREELDAEDYLELQIEQALKNGEVQESMSEVEKVREDEEREKRIAEEAERARLLAEKQQKIDTDKIKARREARGQNWWGEAPEWSPGEILTAEELEKEFANDPEVGNCLLDADEVRIKEQIWVAHNEDWLRKQAERDLLAKTQKANGGNKPGRKSKKGDKIKKKRSKMGDGSVLTESNTPIETPADAARAMLEKRAPQKSAHVDFSALQRIYGRETPSRASSSSPDDSGTPSREQSRNGSESPGPSEPDDRGAPARRRRSSASAQAGDQQEPAAENDPWAVFGEDPPREDEEEEAADFNKATDEFGALQFDNGSDDGSPQPYDYNEDDYGDQEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCE0</accession>
    <name>A0A9Q8PCE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764260.1">
        <property type="nucleotide sequence ID" value="XM_047909600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCE0"/>
    <dbReference type="GeneID" id="71990330"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10452"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO19894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="151" mass="16104" checksum="AEE6F64618899DC2" modified="2023-09-13" version="1">MAPKKKVERGATENISLGPQVREGELVFGVARIFASFNDTFVHVTDLSGRETISRVTGGMKVKADRDESSPYAAMLAAQDVATRCKELGITALHVKIRATGGNGTKTPGPGAQSALRALARSGMKIGRIEDVTPTPSDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCW7</accession>
    <name>A0A9Q8PCW7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="19">ETF-QO</shortName>
            <ecNumber evidence="19">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CLAFUR5_10510</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 19">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="19">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ETF-QO/FixC family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="19"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764515.1">
        <property type="nucleotide sequence ID" value="XM_047909658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCW7"/>
    <dbReference type="GeneID" id="71990388"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10510"/>
    <dbReference type="OMA" id="INFQNCV"/>
    <dbReference type="OrthoDB" id="437331at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000015">
        <property type="entry name" value="Electron transfer flavoprotein-ubiquinone oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049398">
        <property type="entry name" value="ETF-QO/FixC_UQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007859">
        <property type="entry name" value="ETF-QO/FixX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617:SF107">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21162">
        <property type="entry name" value="ETFQO_UQ-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05187">
        <property type="entry name" value="Fer4_ETF_QO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 19" id="KW-0408">Iron</keyword>
    <keyword evidence="14 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 19" id="KW-0813">Transport</keyword>
    <keyword evidence="15 19" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="594"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00052682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="UJO20149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="634" mass="70249" checksum="348F7F6103F58535" modified="2023-09-13" version="1">MPVPSLLTRAATRRFTQLPEVARLATRPAAAGSIASRCLVRGYRPAAVTGGQRRSISQSTRRRFATVNEDDDYTNPLKQEREADEVDVCIVGGGPAGLSAAIKLKQLANEAGNEDFRVLLLEKAGEIGDHIVSGNVLEPSALDELLPDWRSADNPNRFEKYTPAATDRMRFLTKSSSIPMPKPPQMNNHGNVIVSLNELSKWLGERAEEVGVEIYPGFAASEVLFTKEGAVKGVATNDLGIARDGTPKDSFECGMEFHARTTLLAEGCHGSLTKKVIKKYDLRKHSQPQTYGLGIKEVWEIDPEKFEKGLVAHSMGYPLPKSVYGGGWMYHFGDNMVSIGLVVGLDYANPWIAPYGEFQKMKQHPFYRNYLEGGKCISYGARTLNEGGFQSIPKCAFPGGALIGDTAGFLNVPKIKGTHTAMRSGMLAAEATWDALANSNDTEGAVFLFDYEDKLRKSSIWTELKQVRNMRPSFHTPLGLYGGILYSGLEAYIFRGKTPWTLKHPKPDHTATEPADKHQKIEYPKPDNKITFDILTSVSRTGTNHEEDQPCHLQVKDWDAHAAKEWPVYKGVENRFCPAGVYEYVEDESKDIGVRFQINAQNCVHCKTCDIKVPDQDINWQTPQGGEGPKYVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD24</accession>
    <name>A0A9Q8PD24_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764571.1">
        <property type="nucleotide sequence ID" value="XM_047909815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD24"/>
    <dbReference type="GeneID" id="71990545"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10667"/>
    <dbReference type="OrthoDB" id="5367584at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024312">
        <property type="entry name" value="TACC_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12709">
        <property type="entry name" value="Fungal_TACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
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            <end position="56"/>
        </location>
    </feature>
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        <location>
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            <end position="190"/>
        </location>
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        <location>
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            <end position="283"/>
        </location>
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        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
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        <location>
            <begin position="562"/>
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            <begin position="677"/>
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            <begin position="27"/>
            <end position="42"/>
        </location>
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            <begin position="43"/>
            <end position="54"/>
        </location>
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        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
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        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
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        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
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        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
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        <location>
            <begin position="698"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20205.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="741" mass="82135" checksum="BA685D8A144DDD79" modified="2023-09-13" version="1">MESPSNHYAHDVEPSIMLDIDGPPSSPFQSHVESRMISQQWESRPETVTEERTMDIFATPAKSVQYFSQIDVMEDKENMPQSERKTSKLASSTHKMSAPRPTTPERTPLPADDEHLAPATEQRRGSKDSDLMPPPPSTRRTPKRAPLRPSESAANTPRARPTPSCGNSTTSLERVETNSTPSSTSFQAGLDFRASQLSHAPTQDHSGLDDTCFSAFSEIPEMTVFAKLGQSPTKRMEQTTSNSQRTPGRHAEAAPRTTHKRPSPSRSPSPTPRRQKTPANHDGTTFLIDFTQQMDTIGGYSTKSPSKSNTQPDLLKYMNQQRSPHKNNRSSYATPRKENPIMNLLDFELPPAPTPRSVPTITVRELESLKSSYLSQISSLKATLSGREAEVESLKRAVVDAERRVGEAQENLRDEKNKREWAEQEKAGWERRGQEVENVLQSVKEEVMKGEAEKEDLLRKMDDCERRAENAEARAMKAEERFADALAARASSGDGDAADVEDQVQRLVAAQIDSKIEAVSRELHTVYKEKHERKVATLKKSYEARSEKKCADLQHRLSELERQNEDLLAAKDATFSGPVPGASPSKEQKEREARLKAEIEEQRAYLARIESEMQASQQQQDQLMRELEQERIEKGDLVAAVDEMLALQAEQKSAAGDQSVVGDTSVVEDFRKSIKSISRPSGLRAPGGVPTSRMAPPTGIGRARTGTAGKSSILSNIERMGRAGGGAPAAPAEQDPVPRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDD5</accession>
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        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13649">
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        <property type="match status" value="1"/>
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            <end position="443"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    <sequence length="837" mass="93395" checksum="7C5E63B0FD3EB187" modified="2023-09-13" version="1">MASMPARRSSQRRPSRPDQAPRSTSRPSQSPARTRSEDSQTIFVNKPDQEEKPQTQQPSSTFPLPQDDAEPKKCWICFSDSTEDTPETSRWRNPCPCALEAHEECLLDWIADMEAPKNQRGRPGLAAPKIECPQCKSEIKLSRPRDYLVDFYRGIERLGAKAVTPGSLALLSGVVYNFSLAHGMHSIYAIFGSDDGQRILRPVIYNATRAPVEAYAGHPGEASEQLLNVLIDHIVHWRLYVGLPLITPILVLSRTSFADGVLPVLPIIFFASQAHSPNEFIDFAQWPPSASFAFAVLPYFRSLYNYYYKKVWAEREKQWLRAIQPRINETQTDANGEVVDVGDEGQPADNGDGNVFEVRIDGGIWDDWENEDQIEQAIAANNAMAQPDQAAQDGDEGAPGPVVQDNRPVPEGGANEAPAQQAGARQQAQQQQNQQNQPAGGERRLSFSPTAIAETVLGALIFPTLAGFAGEALKLILPSAWTAGRPPIDVFRQTQFLSNPRFRGLQKTGIAGLLQHKWARSLVGGCLLVVCKDALTLYGRTKRYMSSQDLHDAFTSQAKHTVDNSILPKMPDIWKDFNGLLIDDPSFKLTPEVRELFVKYAGIPEDEVVQHVKDVRDRAFKIFPYPCIGQYRFLDFGVSTAPKYNDVLAGVKGGKTLLDLGCCFGQDLRKLVHDGAASANLTGFEMEKDFTELGYDLFRDRETLRSTFVHGDVFASTPNLTEGSFDYVHASSFFHLFSWAEQVELVRKTLKLLNPVKGSMVFGRQAGVKEPGVLKHERTRSGEMFRHDEGSFERMVHEAAEGMEEKERVEVEVEVGMFEVEVEGGKWDFMHYGVVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDM3</accession>
    <name>A0A9Q8PDM3_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910328.1"/>
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    <dbReference type="GeneID" id="71991058"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11180"/>
    <dbReference type="OMA" id="KKWQYTR"/>
    <dbReference type="OrthoDB" id="3914899at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="34777" checksum="D9954466712D0BAD" modified="2023-09-13" version="1">MSFSGGQPSMLPLLYQQHNHYVAELGHTHQALSKLYKKLATVERVLAERQERELSRSDKKKWQYTRSLAKKAVGNLESQQAMLHDHLRQCNNLIASYEQGGEFDTPVTPWTAQIPPSPFLYTPFSPVGASPWTSHQHQPSTNNGTETAPQYWDLSMLRERRLSSPYGSTATADSGFYESVAHGLNVNAEPFNHMNHVYAHELVSPVFYSPFAGSFGTHESSLSPTRRERSDVLPELLMPTSPVKVGAQSSHKRCYSVNAVQLIESRLAAPNAKPQRGMSVGGISGKRNEPDNGLDENTQGGGMSSIIAPETETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE75</accession>
    <name>A0A9Q8PE75_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765201.1">
        <property type="nucleotide sequence ID" value="XM_047909942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE75"/>
    <dbReference type="GeneID" id="71990672"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10794"/>
    <dbReference type="OrthoDB" id="4078573at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF40">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="70"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="658"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="711"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="773"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="786" mass="89473" checksum="22B8AD7B1810317F" modified="2023-09-13" version="1">MSPTAVHPAMSLPRTNSDSPNQKRKEPPNPSGVKPVKKVKRVGPRSDSVPNGDADKDGEGAAKPKRVRTGCLTCRERHLKCDEGMPHCNNCKKSNRTCRRGVRLNFIDTWAERPPTLVTTYGTHDWRVEFLDESREIASEYQGGIQRYKHIKAPDPNPSSAQPLDSAVAFEFPNHGAQVPGMIEQPLSPIQGMMADGYTDQQAQAQAHQANMNSLYDVQPKQDPSPYHSQQVQQIQQQPLSGTTQHSAYPDSGTNNHSGSVASFSNLDASMLEQEPEKERKEFLDNQEETLFMQVFVEEVGLWMDSMDSQKHFSRLLPFHSLSEPMLLNAFLACGARHLTLVNPVYTEEKALHYYDTATRYLLKNLQNPNRDTVICATTAVILNVYEIMSERALQRMNHIAGARALIKECGWNARAQGIGSACFWLNVGLEVLSCLHFNWQVAWDPDDWQVDLDFHRELMNGREEVWTHRMLYIIAKICNFRATMPRETLPTQRDEQIRAQHRHEEWTRLKSMCAAWEAGIPRTMHAVAYLQAYQTSSKSVFPEVWLVKRSTIVARLFFHTAMLLMAQIHPYYYVSNNPEMADMQHRHSQMICGIVAHVKDRGVASVAIRSLAHAAEVLTSRVEQEEVLQIFDKINKETGWRIGFVYKELKEKWGWNEGPSPQEIQQTHTAAKQAQDAQQRQMEEQAQRSASMQLAQGFDFNNRQSIVSMQAQQTTPTQHLQPTPPQPQQKAQSKQKPQRPPAGIPNPLYVKADFNLPQHPYQNFYVPPNNVGFPQQQQGSMYYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEU9</accession>
    <name>A0A9Q8PEU9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dual O-methyltransferase/FAD-dependent monooxygenase CTB3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765520.1">
        <property type="nucleotide sequence ID" value="XM_047910574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEU9"/>
    <dbReference type="GeneID" id="71991304"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11426"/>
    <dbReference type="OMA" id="WTMGGQP"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="142"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="406" mass="43620" checksum="567CE04889CB767B" modified="2023-09-13" version="1">MSTRKPILISGAGLASLLFARSLLRSRIPFLIFERDQSISFRAQGYRLRLSKEGLDAIEDILGPEPNGFPRFWDRCGKTGGSKGFAGIDARTGEDIAESGRPDPSAAKPSGKEVLQSRDGKTIGISRGEMRALFLEGCEEFVKWGHQVTGYELTGNGVKAIFKDGTKSVEGEMLVGGEGIYSQVAKQVSNGKIKTYDTGARGIHGQAPTTAFEDLGEGVWRVVDDSRPDGRVFMITNVRPGGMDDPNNQFGWTLGGQPGVIKPPNNDFAIVGKPAADIAKDLTKDWHPRLKPLFDHMDEQNAAFWKITCSTPSGVPEWQNEPRVTVIGDAVHSMTPAGGIGANTAVRDSALLGRLLAEAGGWKEGIIAAYEKEMRVYGSEAVATSYGMATSQFGVNIEEGVSPTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEV8</accession>
    <name>A0A9Q8PEV8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765546.1">
        <property type="nucleotide sequence ID" value="XM_047910094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEV8"/>
    <dbReference type="GeneID" id="71990824"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10946"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="39335" checksum="08C74197FC57423A" modified="2023-09-13" version="1">METDDVFAPQPPQPQAVLQTAPLMFPAGMIGYPPMSRTPCYKTYTTDFDYDDEMMGPPPPTDEEFDLLHPLPVKKMYFHPGLFPAFTKRGREVVFRVLNLPELLEMILENLDIQTLILSQRVNRRFGVNIHSSLKLQKLLHQAVWDPKAEREKTDLEPFYFNNLLTNHCTTARNLGFIVTRHARGDSGLWEFRVWITTSQLLKPPVRSSVYWAHFCTPGYRSLEIGPELWEEDKHVIKVYYKDMDPDKPLLVLNTMQPSMNHVYHYMEYFRPHMVTTEEELHGGITLGGFAYERFMDGRAYQAKLVAEDVVRAEAVVQNTRIHRAVRRAGKLGEASSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFQ7</accession>
    <name>A0A9Q8PFQ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765938.1">
        <property type="nucleotide sequence ID" value="XM_047908459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFQ7"/>
    <dbReference type="GeneID" id="71989189"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09311"/>
    <dbReference type="OrthoDB" id="3649723at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31857" checksum="83AC12C3927E352D" modified="2023-09-13" version="1">MSTACQTAFGTAELLEIILYGLPTKDLLLAQRVCQFWRNAILGSKKIQEALFLRPIGILDAAFGSPEDDNEQLQLPPARACIYGESSGATWYDRNSGTPVNRLLGNTLAFDNDYGYFDLARLHSFDTALTYREMFITQPAVTSCAYMMAGKFNGFFCAIEDTLQATQGVTVGILMDHVTTYWPVLAKQQSDQMRAAVEIWGVLEIMYDREERYLESVVAGRQVSEEQQAKTPHVFLRGCHSGKEAWSWLTNSQQLEVIKQGLKKGEMAARPASGVDAAVLDNDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFV5</accession>
    <name>A0A9Q8PFV5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766013.1">
        <property type="nucleotide sequence ID" value="XM_047908692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFV5"/>
    <dbReference type="GeneID" id="71989422"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09544"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="276" mass="31348" checksum="55B9A22F1FC15263" modified="2023-09-13" version="1">MTANSKEQPRVIFQDLPAEPASRSTAMSLPNPSLSPSAPSALRLTTAKQSNRRGETYDRKKGAWVLLPPRRTALLHVNKQIHFEATQILLGSNHFSFRNSITLDQCLDVLGQRAQHLRFVYIGGQGYVRKHAKNTFTKLAQSAKFLKKLYIDHYDVCQRSRDYYKLPKSDEVAKRVAKDCKEMLQLLEKSYEEGGVTFNALDIVDYYLQPCCGCPGTARAHNRQMLVATQRELGSCQCACGEAGQQHERMRQELRKWMGKVLEIKVEEGKDARDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG25</accession>
    <name>A0A9Q8PG25_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766135.1">
        <property type="nucleotide sequence ID" value="XM_047908149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG25"/>
    <dbReference type="GeneID" id="71988879"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09001"/>
    <dbReference type="OMA" id="FAEYHLS"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="748" mass="83811" checksum="B963921DF1712423" modified="2023-09-13" version="1">MLSLRLQRARVELQSHRLWLKTFVNGSYHNTWSFDVPPTRPFSTSRRYGEQNSKHAQVRQIVGKNPRTAWQKRERQKADSKQTINLPALSTRVDLMTAILIGDIRTAIALYHSLSGKKPLKPDDFRAIAQLVHQCVRVENQKPFKARKREDKEELVTFSVRLVEDLRHGNLLPNNQAHVHLLAIFKESGTGDAGVRFWRWLQEQDEEYVSTNTYAAAIDLLAVNGTSLDELEELYQTALARFPGNFHAYHLSPEAILPDREQPVVLGQLPLSLLRSIAQARLLQGKANKAYLALDSAFRLFPTSVPPRFLAAFNDERPVSESYTVFAMACRAGIQLPTSHYKGLLAKLRTSSDMTSLSGHMATLRTMLAVTYFHLGANGKVPDNSANEVIIAATQLLRLPGVSTLESKQRRRVVDAVLEAVRKMLEVFAQYGALPAVSVFNSIITNVAGYGRARETIGIALADMDALSLEPNEITRRSIMAAAGLLGDKDLVLKTWKEILDARGKENISPDGLDFHVLIKAARFTEQDDFAKGEYARLQEQVHFKHHKGIEAAFDKPLDEAPGGFITAEEVQDSVQSVLADVAFIEEKTKDRPVVQDFSSQDLPMTLLQPEELRIPDRDMREIYDNMTTEQGSAPTSTPLDAGPPADEAAVATSDTGISFGELRYENWKTMNYLLWLAEKHDRDYDEAVDKAIARGVRPPKRDMSITREEVEGMKSFGLSASRASHSKAKSKDVEEARKEIARLRTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGA3</accession>
    <name>A0A9Q8PGA3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766314.1">
        <property type="nucleotide sequence ID" value="XM_047908634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGA3"/>
    <dbReference type="GeneID" id="71989364"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09486"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000066">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="83"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="51197" checksum="375DC5B51D37D9B1" modified="2023-09-13" version="1">MVCVACIIQIGTRRVATTFTSSARAKRTMTTSINQAVEAIRSFATSARTTSLKDGPLTDVPQAPKDPMFGLSAAYRADTFDRKVDLGVGAYRDENAKPWVLPVVKKAKEILNQNPELNHEYQPIAGFPEYTEASQRLVLGNNSKAILEQRARTVQTLSGTGALSLAARFLAAYYPDSSAKRVWVSDPPYVNHLPIMQNAGLETGIYPYYASQTKSLNFTAWLDKLRQIPAESIILLHACAHNPTGVDPTHRQWEQIAEVMKEKRHTPFFDSAYQGFASGNLDNDAWTIRHFVEQDFDTVLIAQSYAKNFGLYGERAGALHVVTLSPDLSQRILSQLTRLQRVDISTPPAFGARIVATVLNDPRLFAEWQDDLRTMSGRIIEMRQALRAQIERLGTPGGWRHVTDQSGMFCYSGLSKEQVGVLREAYHVYLTGDGRVSVSGLNGSNVGYVAQAVKEVVSGGGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHM4</accession>
    <name>A0A9Q8PHM4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767180.1">
        <property type="nucleotide sequence ID" value="XM_047911303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHM4"/>
    <dbReference type="GeneID" id="71992033"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12155"/>
    <dbReference type="OrthoDB" id="10050400at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031942">
        <property type="term" value="C:i-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24145">
        <property type="entry name" value="Mgr3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="47852" checksum="2BCF7BFC41958849" modified="2023-09-13" version="1">MSGRPVLSLPLRQAFRQLPRSSRRIHNASARPTFQRSPTQCLHQRRHAGSFSDNAKKLFRDSPFSISMAAIAILLGAGGVMYANYIYQSYIIASFHNYPEEVAKKLRRAIFYTNVDLQPQEAIKYYRQALQVADEVGMDPFSDEIMGVKIQVAKLMEDIQQWHKAIEVLERVRADNFAWLAQRGGLPENKKKRTNVLAKTVGISVKLGELYGAPAIYDRELAQERLVWAVETVLKERQRRQSQQVNEEEEGPWMNDEEVGAALESLAHSYEAKDQHYLATPLFLQALSLYPNKDCHQVILMNNLASSLAQQSPQASREAQVHATSRNINERPTGPAASKESMIENARIWAQKALDVAAAIKPPVRNGECDVGCAVALHNLGEFAEMGKDIDLAKRKYQEAIGLARAIGFQEGIEQSSARLRELAKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHX2</accession>
    <name>A0A9Q8PHX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hybrid signal transduction histidine kinase K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11906</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767098.1">
        <property type="nucleotide sequence ID" value="XM_047911054.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991784"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11906"/>
    <dbReference type="OMA" id="AMCNLIM"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058846">
        <property type="entry name" value="PAS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF30">
        <property type="entry name" value="TWO-COMPONENT SYSTEM RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26131">
        <property type="entry name" value="PAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="955"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="1028"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1104"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1434"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="269"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1378"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1576" mass="172241" checksum="B4FE05CD99B58994" modified="2023-09-13" version="1">MTSSDKPSIFTSRDSLPQPPPRTNAAPGRAPRTSSPFRRQSTSEYLGVLGPTAIPPAVGDAVADDTTAASSAADPDPSTLPIVNKNTEEGSTPLPSSNTASPSIWNSFTGHIPSASSTAAPEVRRASVSSGQPDTTSSPYERPSAPLFPRTPPTSAPTSHPKRKHAPATPRSDSQDPGSEPSSKRARPRPRLKHTLDSNTYGSSTFAPAVEPPSPLFFSNSPRPRPTLPPRFSSSEAAARMLSKTRAEDSHVKTVSLARGTVTTPAVGIPLHNTNITSAPHRRSLERSITGRSSSPDTISNGAKDGHSGMTGMLNSIGIIELLEQDERPTFIVDLGDSSNYGPGQLHLLFANLSLKQYDGIVSLVAGTSLEEFSPGAKTFLQFKSWLLSAAINGESLNVCLSPFSYANMTWSYSTLRKRLRIISGAFNTPPASSTAAMRVSVPPGGTIPEQLEMVPEVHDYFGHAGQESRIPESSNNSSVSGVLPTTESGQAFAHDALLRVPPDLDLSGATDLLPNPSTYVQPSLNAGANDLTPGAMSVVSSSTSNQSRLANDGMTNSQIATVSSDSPSFDWTRLPVTDSMPKHIQFARSIDWASTSLGPIEDWSSDLRQMCNLIMASPHPAAMYWGDDLIAIYNEAYILLAGQKHPSLMGKSYRVAWSEIWNEVKDVFASARTTGEATMKDDDCLFIRRSDHLEETYFSWSIIPMVGRDGSVMGLYNPAFEKTRRKIAERRMLTLREVGERTASARDVKGFWAQVLGSFEFNEYDSPFLLLYSVADENDSDTGSIHSNSVLSTRQAMLEGSLGIPDGHHASPAVIDLKTGMEGFGPVFREVMKTDKPVLLEVGSRDLPASLLDGLEVRGFGDPVKAIVICPIHPTTGDLVLGFLVLGVNPRRPYDDDYGLFVQLLSRQLATSLASVVLFEEEIKRGQRAAKLAALDRIELSEKLAARTAEAIESETKFTRMAEFAPAGLFIANSQGKITFANDVWYDISRVPKDSSMADTWMDAVKPEDLDLVRRSWTDLVVNAKAISIEFRFKAKWRDSDGNSSDTWVLFSGYPEKYDDGKLKSMFGSITDISQQKHAEGLQFRKMEEAVEMKRQQENFIDITSHEMRNPLSAILQCSDEIATSLTRFRQGGDRTVPDELIASCLDAAQTISLCSQHQKRIVDDILTLSKLDSQLLLVTPVDAQPLTVVKRALKMHEGELQAADIQMKFVVDQSFRDLDLDWVRFDPSRVLQVLINLTTNAIKFTGTESRRTITVTIAASTKPPSELPNVPVRYFPTRRRNETLMDEKDWGDGEKVFIHFGVRDTGRGLSPEEKKLLFIRFSQASPRTHVTYGGSGLGLFISRELTELQGGEIGVESEAGKGSIFAFYVAARRTTAPQDTTDSGVGAKRHNPPSSKSKSTPMVPPAEKGIVVPRTEDSKTTRGTNGQKPAKKVLIVEDNLVNQKVLQKQLKNNGTEVHLANHGGEALEKLMQSTYWLDSKPTDQKLELGVVLMDQEMPVMDGLTCTRKIRELEAEGKLTGHIPIIAVTANARAEQIQTALDAGMDDVVSKPFRIPELMPKIEELMERYPMPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI58</accession>
    <name>A0A9Q8PI58_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22956.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="16084" checksum="0E6602DC54F35D2F" modified="2023-09-13" version="1">MRSQLSNVQNHLDLARPDVAEACTIENTLNQALAKLNTETQAMRHEMSARLHIEAESLATTMARITSEGDRMKQEADRQANEAKNAKAAADRMATEADRAAREKQYAAEEWKSLKKQLKKLDAKCEAMNVTQPQSVKGRFREV</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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        </citation>
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            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
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        </subcellularLocation>
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            <end position="207"/>
        </location>
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        </source>
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            <dbReference type="EMBL" id="UJO23398.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="508" mass="56585" checksum="02E010968FBD92BC" modified="2023-09-13" version="1">MWSQDVASRPVAAVETQGTSPFAVHQGDFDSAMDEFFRLNGGWRPTESCTHCPRLCLQCFILQTTSDNPDPVKACSSCVALFRECSLAGPEKRQAATFETAQPVIGQLHGVYEDENMAQASSLNSSMHPDNNASANLFDVTTLSTGSKRSSSRSRFKTRPLRIWLANHSDHPYPSEPERDMLVHITGLSDTQVSNWFKNARRRQRQAAGTARHNSRKVFRAGSPMPRATASESTPMERWRNSPPEQEAASIGAIETALVEWTGSSHAASATGDAWDPSSATASVDSNSSASMWHASDSSSAASLAFSRASSNSRPTSANGIRKRQRGKRTTTASCILHCTFCSRTFTKKSDWTRRERNMHLPDLDAWICSDLVKPDESTIVWTIGSAKPQCTPCGQPEPAEAHIQTHDFASRADRVLAERKVYRKDHLWQHLTKFHHCSKWDGWTLDSRIESLRQQIDAVDSTCGFCQLQSYSWEARIEHIVQYFQDQINDISQWQGGYGIHDPGASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ74</accession>
    <name>A0A9Q8PJ74_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_12849</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
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    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="30"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO23402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="14945" checksum="50945D7FB1AA47AF" modified="2023-09-13" version="1">MAPKAAQKTPTTAGKAPAGKAPAEKKEAGKKTAAATGDKKKRTKTRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJC8</accession>
    <name>A0A9Q8PJC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <shortName evidence="5">AS</shortName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aryl-sulfate sulphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12603</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aryl sulfate + H2O = a phenol + sulfate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:33853"/>
            <dbReference type="ChEBI" id="CHEBI:140317"/>
            <dbReference type="EC" id="3.1.6.1"/>
        </reaction>
    </comment>
    <comment type="PTM">
        <text evidence="6">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768080.1">
        <property type="nucleotide sequence ID" value="XM_047911751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJC8"/>
    <dbReference type="GeneID" id="71992481"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12603"/>
    <dbReference type="OrthoDB" id="96314at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005539">
        <property type="term" value="F:glycosaminoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008449">
        <property type="term" value="F:N-acetylglucosamine-6-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018958">
        <property type="term" value="P:phenol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000051">
        <property type="entry name" value="Arylsulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040319386" description="Arylsulfatase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000972-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO23714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="69036" checksum="283F86EDB6B660CF" modified="2023-09-13" version="1">MPTITRACLLALRYLASLPLFLALDVPQVPLKSSKQPNMVFILTDDQDLHMDSLSYMPYLKKHLTDEGTSFSRHYCTVALCCPSRVSLWTGKAAHNTNVTDVNPPYGGYPKFISQGFNSAYLPIWLQEAGYNTYHVGKLFNAQTVDNFASPHAAGWTGSEFLLDPFTYEYLNATFTRNGEEPVSYEGQYTTDLVAEKSFGFLGDALASDKPFFLTIAPTAPHSNVHIGSNIIDGNFSEHSNVQSPPVPAKRHEHLFEDVIVPRTPHFNPDDPHSVSWIGLLPKQNQTNIEANDHFYRSRLRALQAVDEIVDDLVKRLDEAGILDETYIFFSTDNGYHIGQHRLQPGKQCAFEEDVNVPFIVRGPGIARGKTTDIVTSHTDLAPTFLALANGHVRDDFDGSAIPVTQLDSEITAQPWKNEHVNVESWGIIMSEGKHGAVLYPNHTYKALRVIGDGYNLLYTVWCSGEHELYDLTMDPYEASNIHPDATRASKLPPANIVLDSSRPHRADQQVLYTSDVVPSGSTIANSANALSVPKVLHRLDALLMVLKTCRGRECTHPWEMLHPKGDVHDLKDAADPIYDHFYEHEQQRVKFDKCEKGYILESEGPLHIKPYLEGIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKU6</accession>
    <name>A0A9Q8PKU6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Carboxypeptidase</fullName>
            <ecNumber evidence="15">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_13481</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Preferential release of a C-terminal arginine or lysine residue.</text>
            <dbReference type="EC" id="3.4.16.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="15"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768711.1">
        <property type="nucleotide sequence ID" value="XM_047912629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKU6"/>
    <dbReference type="GeneID" id="71993359"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13481"/>
    <dbReference type="OMA" id="EMADQFV"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000121">
        <property type="entry name" value="Carboxypeptidase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF190">
        <property type="entry name" value="PHEROMONE-PROCESSING CARBOXYPEPTIDASE KEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4 15 18" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040538358" description="Carboxypeptidase" evidence="15">
        <location>
            <begin position="37"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="552"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="590"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO24345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="633" mass="70531" checksum="CDA69C79E98AC210" modified="2023-09-13" version="1">MAYTPHPPARRRHSPWSALLSVATLLSSIWLPVAQAAKSASDYYIHDLPGAPSSPRLDMYAGHLEITPDHHGNLFFWLVKNRHIGDKKRLVLWLNGGPGCSSMDGALMEIGPYRVKKDGTLRLQDGSWDEFANVLFVDNPVGTGFSYVDTDSYVHEMDQMAEQMIAFMDGFFKLFPDHEHDDIYIAGESYAGQWIPYVAKAIVDRNKANQKHKWNLSGLLIGNGWISGPDQYISYIPFAYEAGILQAGSEADRTATRQQQDCLKALNEPGAADKIDVAVCESVMQEILRNTQSSPADQACVNMYDVRLRDSYPSCGMNWPPDLAQVKPYLRRDDVKKALHINVDKKTGWVECNNQVGAAFTAKNSKPSMQLLPDLLEKMPIVLFSGDKDMICNHIGTENLINNLKFNGGTGMQSDGMTSMKHDWTFEGEPAGQYQTARNLTYLRFYNSSHMVPFDYPRRSRDMLDRFMGVDIASIGGTPVDSKIDGEKGTEVSVGGHPNSTAAQEEEASRLQEAQWNAYRRSGEGALAVILIAAVAWGIFIWRSRRRRRGYQGVIGSDPYDDGRGDGLGLNGRKAERDVEAARAYDEAELDDMEVGRIGKSKERSNMDDDDAFALDDEDEDEGPRHGRANGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKY5</accession>
    <name>A0A9Q8PKY5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71993862"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13984"/>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
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        <property type="entry name" value="QUESTIONABLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="581" mass="64452" checksum="D6AC5946D40824CE" modified="2023-09-13" version="1">MTTSGLDHLPADLLNVLPSYSLAIHQPFDRARPTQLKQGAVLYLFGADHMKQQNAHRTGIYEHGVRKLDPGQQNPLSVVGDKDFVFEHPILVISRPCNEPGVIHFCSMTSFGGRTVQEQFKGNRQLESQFYLALQRVHPIITHLTLNYARGAIARKSGYVRTDTVYSASIANVVRFHNGKKPEDQMNSDAWDLDEASLNCVLWFVQQHTGYVPTTQHKLTEMEQLQSHNIFLEHVLWAVRQREQMTKTALNKTQLDHIFGGDDEAAVPSPTEALYDMTDVEGQRITVRLPLASTSVVEYVSSSRENSSAHGGERYVIPRRGQHTAAADTIMPDARTADGAETNESKHATASTNDSRFVAGHVASSAHAVSTTAAEPRRPGSSTLASYDEILEPILAEHDGSYLVRLGAHYTALSGGFRIPRREDFIVDNTTVAFMPRAMGEVNKEHQYKAFSNIIYAVTTRSGQLPYNFTRPLWMVNVSFTIEHYYEPHRMKGKLFPTSDSEMVVFITRNLAVDGSSLAFAIPSSGISSIDCSGSDYVLRTDGIDISFKFAGNRSEKVATSVIGGLQDMVGRYSLTGPREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLK7</accession>
    <name>A0A9Q8PLK7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLK7"/>
    <dbReference type="GeneID" id="71993514"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13636"/>
    <dbReference type="OrthoDB" id="10578486at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="832" mass="94824" checksum="07692904F52330C5" modified="2023-09-13" version="1">MAAKRSRSKKSSKSPQKDDKKTSPQASSAKKSTPAELSLRAILQKPSFKAGNKKSSTGRQPSLEHAMDNLLSPAQLADDEYTPPARPVRGKISTQTTSKLPKHVKKRASKENPIDPDLMDITEDVPWTRPSASRTSSLRSSSSPQLREAAAVDTFERNRESNLAAPFPRNNAGHPGPQYISRGPVVDGFTQPRPEQRDDYTPPVQHVETPYLGPEYANPRDQAEALLAGRTSTCRMPTGGRSYRTQLLDSLRELGFGYHATGHPIPPLTQAEWRARGQSQNPVAVWKSYDDYGILPRWAKPSYPGFRDPRNDRFGNKHSDRSVRAYWTRYTNMCLGAEEHAIEEYCCELFREAHGISDEEFEYNKSLTLIDRKFRVVRALHRTNPVVDDWYSALPDSDREEVFDELEPDLLDGNRILGRPVRRLWKVVRVPHHVFKEGDEEPGSALDAYWDYRGSGIIPKGTQKYIAYPQREDIDGDGDLVDDPMDLEEDPQITAIRECQYQTSLRRAEQLYIYEWTKCRRAIELGLTHDEFDWYLATGKIDPAWSSLTPDGRRQVRSAAPAPPPQPPTQRPLYARPGRRARPDPPAVGRRLLPRPTEQRRQFTSQPPQQRAMHNPAGRGLYQRPGGNPPRIFNPPANLRPDGPRIREPEPHIQWILFGHNYGSYRANAINNILITAPHTPIPPRSAGDAAVYLHAYTCQGRLPSPAGYVQPSFPPVRGEEEFEEWEQWDEYLRNHERSCRSLEQNSVLRFLRNMRAGELGLTYEEFKHNRAEGRITGYAEGWNVERQLVRGASQGLERSESRWTVDARQEEARYNLPAPGERRIRRSVVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLL9</accession>
    <name>A0A9Q8PLL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl hydrolase 5 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769161.1">
        <property type="nucleotide sequence ID" value="XM_047912889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLL9"/>
    <dbReference type="GeneID" id="71993619"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13741"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040145878" evidence="1">
        <location>
            <begin position="25"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="470" mass="52783" checksum="8671668EA9A312F8" modified="2023-09-13" version="1">MPQIVPKMLSVVLSAALLLKSASAQALSYDSQHQLYPRQTSTNSSSWPYGPFSTRGRDIVNSRGEAVTWAGVNWPGSGETMVPEGLEWASVEDIVDQITSVGFNFIRLTYADEMINQIYARNGSDIPLEVAMINGLGYENGTKVTNEIIARNPGWSKDTTRFEIWDKIAQVAASKQIYIHPDVHVGKAQWCCNNTDGNAWFDDYNFPVDNWKRGLQYIANWAQGHENVVSMSLRNELRRAINVTSPTSTIGYNWLSLVGNYTSATDAIYETNPDILVTWSGMQYDQDLSALTTGLNLNTAPCYKCDAVRDGVRREPMFFDLASHPWADKVVWELHLYSMSENLDTGNCPIIEAELYQSGFNALGIDKPAACNITGDCPEAVRQTPVIMSEFGWAQDQTLFNDTLQGCIRNFTTAHNISWAMWSLAGSYRIRSGGQGVPDTWALTNYEWNGWQFPEGIERWWKPWVSAMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLP9</accession>
    <name>A0A9Q8PLP9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metal-dependent hydrolase lscR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769206.1">
        <property type="nucleotide sequence ID" value="XM_047913435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLP9"/>
    <dbReference type="GeneID" id="71994165"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14287"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070290">
        <property type="term" value="F:N-acylphosphatidylethanolamine-specific phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070291">
        <property type="term" value="P:N-acylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070292">
        <property type="term" value="P:N-acylphosphatidylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000048">
        <property type="entry name" value="Zn-dependent hydrolase/oxidoreductase family protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024884">
        <property type="entry name" value="NAPE-PLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038896">
        <property type="entry name" value="NAPE-PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine</name>
            <dbReference type="ChEBI" id="CHEBI:62537"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine</name>
            <dbReference type="ChEBI" id="CHEBI:62537"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038896-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="409" mass="45694" checksum="9EFD8E86FAFFAB4F" modified="2023-09-13" version="1">MSCLRLCRIRNISSSLTRKLSHAHKMSTTTTASSKTSTVHITQPAYTLPSPPEAKDLKHHLKRNQVFENPWPSFVDPGGFTVGVKMTRRKIQGKDVSNSSSSTLAVRKPHFHPSRKQDDALRATWLGHACYLLEFPSGFRVLFDPVFEERCSPISFLGPKRSTPAPCQVADLPIVDAVVISHNHYDHMSYPTLTAIAAKYPNVRFFCGLGTARWFKENGMPIVVEMDWWESSTITLEGEEGAVEATISCLPSQHGSARTGIDRSRMLWSSWAIQSGGKSAYFAGDTGYRSVPELPDNEDDYSPKYSSLPVCPAFKQIGELRGPFDLGLLPIGAYQPRFIMSPLHSNPYDAVNLLVDTQCKKALAMHWGTWVLTEEDVMEPVRKLGEAVRWRGIEEGVFEVCEVGESREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PM15</accession>
    <name>A0A9Q8PM15_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PM15"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="86" mass="9546" checksum="B51A67988F992EB6" modified="2023-09-13" version="1">MISTLRREQVPTSIRTGLVRGAFDDEDLCTQCTYKHTNANGFKQHPEKNPRSKGKDSRKEETLNQKVQGQKGKGKGKAAAAVEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PME2</accession>
    <name>A0A9Q8PME2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769466.1">
        <property type="nucleotide sequence ID" value="XM_047913684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PME2"/>
    <dbReference type="GeneID" id="71994414"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14536"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="19995" checksum="C2F1C6A486EE1568" modified="2023-09-13" version="1">MRCSCAVSKREGKSSTSLAVLAPILRLQFLDPRKLGSGFTSTLPSAAAIIEQHGAIRGIVINAKEESVVFTASMESYRPNKSVLSAPCGALKAGVLDMTHTLAMEWAQYSIGVKSASPSLPDWERQLKYYGGMPRLAKVEESDGAYVHSLSDAASYTTSKDIAVNGVIGSKFSVFIALPMCANNATVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMH1</accession>
    <name>A0A9Q8PMH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-hydroxyaverantin dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769504.1">
        <property type="nucleotide sequence ID" value="XM_047913448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMH1"/>
    <dbReference type="GeneID" id="71994178"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14300"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="29213" checksum="F290755C90DB82BF" modified="2023-09-13" version="1">MEALNTNVDLASLEGRSVLITGGASGIGLATAKAWASAGAYITLADIQPLEKGQKLASDLSHNGQHVNYAFCDVTSWESQLEAFRSAVRFSPRQTLDIVATFAGTAFAPGNEVEHVLFAGEPSLDADLKSPNTKNIDVNLTGVYYSSFLALYLFRLPASDASPPGDKSLIFVSSIGGYMDSPKASTYPASKFGVRGLFRSTRARTLELGVRCNLLAPWFVDTPLIAPVKSAMAKRGVEMGRVLAFATMEDCVSAASFCAVDGGLHGEGFVGEGVGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMI9</accession>
    <name>A0A9Q8PMI9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769538.1">
        <property type="nucleotide sequence ID" value="XM_047913601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMI9"/>
    <dbReference type="GeneID" id="71994331"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14453"/>
    <dbReference type="OMA" id="STRHRMA"/>
    <dbReference type="OrthoDB" id="10611739at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="46981" checksum="F9421A7A4AD7DA85" modified="2023-09-13" version="1">MAPVTRAGRMMQQAGEISPPTAASIVTRSTSTRHRMASRASSETSKTTRNAQQPRATSPTQLVTLPPEIFERIAEECNDASVKAPRLTSHESASKVLRTYVSTFFQDLVVLPCLEESLQNISKILRHPTFGKVVRSLSVCPKVMESSSKQDLHRIRQRADKMRESEKDFTMLREFFEQLMLQGRSIEVVITTVDDAVRKPSAHSLLLSQDGMLTLCHYRHHIASITTDAIIRSRVKIQHFSMQGEYGIGATDFTHDPRRGILETLCMRLSSLELVVWCNYRLWGDSGGEFGKVIACGSQFQHLSLDVHWDGEGSTSIYGMGSGRSLNSATIARGVLSGAFPALESLKITGAEISCNNLLHFASQHKRLSLTSLTLVNCSIFGAEDLHLQEDCSAAVEDALRRLTGLEGVQVTAGNRILLYFAAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMK5</accession>
    <name>A0A9Q8PMK5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769510.1">
        <property type="nucleotide sequence ID" value="XM_047913741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMK5"/>
    <dbReference type="GeneID" id="71994471"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14593"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="357" mass="40423" checksum="7E3917028B77BB1A" modified="2023-09-13" version="1">MSATVAADNVLPIVATTTPAPAPPSRSNTVSSATMEADEHEHDSTFGGDRESLASSSTSLRSAATKFQFENGRRYHGYQAGKHYFPNDEKEMERQDIEHQNQILQMDGKLFLCPLVENPTEILDLGTGTGIWCIDMADQYPDCQVLGTDLSPIQPGWVPPNCQFQIDDFDHEWTFGSNRFDMIQHRFLVGSVKNIGELYKRAFDALKPGGSLQGVEIQFGTFCDDDSLPEDAALRQWTSLMEDAFGKIGASPPMAEDYERWMRETGFENVHMHIFKRPMNDWPKDPKMKEIGRYCCLNWLEGVEGFTMAPFTRILGWSPEEVQVFLAKVRKESVTRRIHAYMKGIVVWGTKPLHPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP9</accession>
    <name>A0A9Q8UQP9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_06684</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763261.1">
        <property type="nucleotide sequence ID" value="XM_047905832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP9"/>
    <dbReference type="GeneID" id="71986562"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06684"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="229"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO18895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="735" mass="83218" checksum="1115EBF86B54D417" modified="2023-09-13" version="1">MLSSTTIRVTSLQNIRLARNSFLTSTSAFTTSGAKTSSPEWIRSFSQTASSQKFQVPIRTRNSRNTTMADDYKTRAGQIFNRDAFESLIKRKQFYWQSFEPYGGTKGLFDYGPPLAAIEAEFTNIWRDHFVRSEKMMELKCSMLTPYPVFKASGHVERFNDFMCKDTKTGDILRADHLIKDVLEARLKGDKEARGEKVSDAPEDPKKKKKASKVKNEAVKLDDAVVQQYNDILATLDDTVAQWGQMIKEHKMVNPVTGNEVTDPVEVNLMFPTQLGMSGKEQAYLRPETAQGQFLSFPKLVEYSDGQLPFASASIGYSFRNELSPRNGLLRVREFLMAEVEHFVDAEGGKKHPKFASVKDVELPLLDRDTQSGNEAKGISPSTTPQTMTIGKAVETKLVDNETLGYFLVRIYRFMERIGVDTKKLRFRQHMANEMAHYASDCWDCELQGSYGWVECVGCADRSAYDLSVHEKATGVPLRIREPLKELQHIEEYVAQLDKKESGPKLRKNVGAVQAALDDLTQDIKEKLSISLQEQGKVEVEVPNLGKIQLGKELVKIEKEKRTVTMREFVPNVIEPSFGIGRILYHLLEHAFWVREGKDEARSVMSFKPTVAPMKVLVVPLQKDQKFASLIQQLEDRLDEEGLSYKVDQSGVSIGKRYSRNDELGIPFGITIDYESLEGKTAGTFTLRDRDSTKQVRASLDEIVEAIAKVVKGKWSWSDVQQRLPAYEGKEEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQU8</accession>
    <name>A0A9Q8UQU8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GDP-mannose-dependent alpha-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07568</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763454.1">
        <property type="nucleotide sequence ID" value="XM_047906716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQU8"/>
    <dbReference type="GeneID" id="71987446"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07568"/>
    <dbReference type="OMA" id="HTNFPQY"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="4">
        <location>
            <begin position="123"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="3">
        <location>
            <begin position="300"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="543" mass="61107" checksum="08C53ADA8C89CAE9" modified="2023-09-13" version="1">MAAMQRVDSGHESPKSEFPAELIGRKVLLATESLGPVNGVSRTTQSLVDYLRDHGVHVATCAPYYKGQHINQDSKPDRQPIVNKEWVRSMEAKSAALGARAIGGAWNWHNDRLDQDKETEPLLQQQHRPKLFNRTRSEDAKRKIEQSRLSRINPEYRLQGQALPYNPDLTVAFPFRLGKVYDRTFKPDVIYLASPASVGFQFLVQLRQLDQPPPTLLNFQTDLAAYASILFAQPLDRYGVWLLKIVQGFLFQAAAVHTIFYPSAYVRKYMEDCGAPSEKMIQLGRGVDTELFNPIRREEAYRQEIATDGEIIFCCISRIAPEKGFEFLAQAAEKLKVSGLKFKLLIVGGNKNPAVEKEVRDYFKNVKDQTVFTGMLRGTALARAYAAADVFLHCSITETFGLVVLESMASGVPVIARAEGGPAETVKHGISGYLTEPDDMDLFVEYAKHLATDHELRGEMVCNAREQALNTTWDKINNQVAIQLATALREQPPLSAEQKAKDGYYRTWKNMFGVYLAVGVVWFFWLIAVIPLMLCGWVHGLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQV1</accession>
    <name>A0A9Q8UQV1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763428.1">
        <property type="nucleotide sequence ID" value="XM_047906432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQV1"/>
    <dbReference type="GeneID" id="71987162"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07284"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="16245" checksum="A7830CFC6B2F2D9A" modified="2023-09-13" version="1">MEQSCNTIEASSTPKQSQTSAESIRGLIDAIHTDSYFSIFAQELPKDKLDEALRIARKELSHHKQQYNTAVQSAEKRKLNVERNKITEKPVKLKGVKESHAERDPNEVKEKLIKLAEAARKYRVAARAIENKVEKASESLKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR88</accession>
    <name>A0A9Q8UR88_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06757</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763832.1">
        <property type="nucleotide sequence ID" value="XM_047905905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR88"/>
    <dbReference type="GeneID" id="71986635"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06757"/>
    <dbReference type="OMA" id="HEGAGWV"/>
    <dbReference type="OrthoDB" id="1560166at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08278">
        <property type="entry name" value="benzyl_alcohol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF2">
        <property type="entry name" value="GROES-LIKE ZINC-BINDING ALCOHOL DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="13"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO19466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="376" mass="40629" checksum="4504BAFB61BDBE6A" modified="2023-09-13" version="1">MAGLRTPAYVVHDAAQDFKLEEISLGEMQGNELLVEMKYSGICHTDLVFQQGKLRVCEYPAVFGHEGAGWVRAIGANVKDKDVKVGDFVLLSINFCEKCKFCRRGHPADCVEGTRLHLFGVRDDGTTAATLSGSAESVRAHFFGQSSFSRFSYVHETCVVRHPYPPQEAAKFAAMGCGYQTGAGTVLNILKPEPDGSIVVFGLGAVGLSALMAAKSLGLERIIAVDIQELKFPIAREVGATDLVNSRDIDIAAKLKDLTGGAGVDYAIDCTGVPSVIEAMLNSLAMRGSAATVGVPPTGAKVQIDPLVYLLGSRRCLGCREGDSVPKEFVPQLVAMQQKGLFPVEKLVKEYDYRDMEQALKDMHDGKVVKPVIRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URB0</accession>
    <name>A0A9Q8URB0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763906.1">
        <property type="nucleotide sequence ID" value="XM_047906027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URB0"/>
    <dbReference type="GeneID" id="71986757"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06879"/>
    <dbReference type="OMA" id="DAMAFWI"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF3">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G03960)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="110"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="22191" checksum="E2B8892BC1888C4D" modified="2023-09-13" version="1">MSTPRSKKEIPSTVHQTTVDHFKAQPWTRPTLQDPAFRIVSMSREVTHGGHGHTLMGRTWNTDSTVQHLLSLSRPSTASDPSSFPQSETDRAEVRRFYTFGKDLNAHPNLLHGGVIGCILDSTLGGVVGMALSQTAETSTMFTVQLNISYKKPIKTPGSVMLRSWVTKVEGNGRKVWAKGVVEGEGGVVHAVAEGMWLGAKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URJ4</accession>
    <name>A0A9Q8URJ4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-dependent monooxygenase orf3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764148.1">
        <property type="nucleotide sequence ID" value="XM_047909432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URJ4"/>
    <dbReference type="GeneID" id="71990162"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10284"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000153">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="138"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO19782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="438" mass="47962" checksum="8F03BEB2ABD48758" modified="2023-09-13" version="1">MPSTTPSSKRDFDLAIIGGGISGQTLAIALHTRGLRVKIYEQAPSFGEVGAGVAFTGNAVQSMKHCYSGIYEAFEKVRTGNIWDSKKKVWFDYHDGFSVKEGGEGTWAFSIVNQLGQAGVHRARYLDELVKLIPEDVVDFGRRLEGLGRDKKTGRHVLHFHDGSTATATAVIGCDGIKSKVRSLMYGPSHPCSKPTYSHKYAYRALATMEDAVKAVGEEKAKNACMHMGPGGHMLTFPVNHGKTLNIVAFHTTDDEWPDDSHLTRPAKREDALKDFEGYGSDVRNLLELCQPNLDVWAIFHLGDNPVPKYNYGSVLLIGDAAHATSPHHGAGAGFCIEDSAVLADLLADERVKSQKDIAAAFETFDQVRRERGNWLVQTSQHIGNCYEWLAEGVGEDFKKIKHEIDTRNGMIADVDVASMCREAKQRLGASLAASGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USC9</accession>
    <name>A0A9Q8USC9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765003.1">
        <property type="nucleotide sequence ID" value="XM_047910139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USC9"/>
    <dbReference type="GeneID" id="71990869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10991"/>
    <dbReference type="OrthoDB" id="3626626at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="146" mass="16766" checksum="3E90DFFB78748C61" modified="2023-09-13" version="1">MRMTQYLFFQISRTVMDKTINTTSTMATLDSRIASLPQELQDIILDFTLSATNPLTGRAEIAHDHRPPLSLQINRTLRSKFAAHYYSTTIFTVRLCYKLCPLETRAEHLYHLRIRNSPADQREGEAGGDHSWTRTLAASLHQVGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USN6</accession>
    <name>A0A9Q8USN6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Beta-galactosidase</fullName>
            <ecNumber evidence="4 13">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_11521</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="4 13"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765390.1">
        <property type="nucleotide sequence ID" value="XM_047910669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USN6"/>
    <dbReference type="GeneID" id="71991399"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11521"/>
    <dbReference type="OMA" id="NEYSGAC"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.20.10:FF:000001">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000065">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000088">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040159793" description="Beta-galactosidase" evidence="15">
        <location>
            <begin position="22"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="16">
        <location>
            <begin position="396"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1011" mass="111437" checksum="240B3697FBA33BC3" modified="2023-09-13" version="1">MLFGKLLKAAVLSVAAVQTAALTIGGKPNMMIKSYKREALQDLVTWDEQSLFVRGERVLFYSGEFHPFRLPVPSLWLDVFQKIKALGYNGVSVYFDWALLEGKPGQFEAEGVFALEPFFEAAQTAGIYLIARPGPYINAEVSGGGYPGWMQRVPALLRTRDPAYLEATQNYVVNIAKLIAAAQITNGGPVVLFQPENEYSQATDNIEPFPDPMYFQYVEDQFRNNSIVVPFISNDARPQGYFAPGPPRQEAALDIYGHDGYPLGFDCANPYTWPDNALPTNYRDLHENQSSSTPYSIVEFQGGAFDPWGGPGFAKCTALLGPEFERVFYKNIYSFGATIFSTYMTYGGTNWGNLGHPGGYTSYDYGAVITEERTVDREKYSQAKLQAQFLQASPAYLTAFPQNNSNANGSYTGNGAIATTALLGNVTNFYIVRHGAYNTLDTTDYRFNFPTSKGNITVDGLSLHGRDSKVFVSDYDVGGINLLYSTAEIFTWKQYGNKRVLVVYGGPGETNELAIAGAQTGKCVEGQGVTTDSKNGVSVIRFKTSSERKVVEVGDDLSVYILDRNSAYNYWVIDLADDSVTKNYTNYKHATSAPIVKAGYLLRTVQAHGSSLHLTGDINCTNPVEVIGAPEPLHELTFNGESLNFKQAKNGVVTATAEFKKPELTVPDLSSIGWKVIDTLPEIESNYDDSAWTVADLTYSNNTIRNLTTPTSLYSSDYGYHTGNLIYRGHFKANGGEKELYLATQGGSAYGHSLWLNDEFVGSFYGGDKYYTWNTTYTLPNTVAGKDYVITVLIDNMGLDEAFTVGSEQMKRPRGVIDFNLNGHNKSSVTWKLTGNLHGEDYEDHTRGPLNEGGLYAERQGYHLPGAPTSDWKDSKTGPMEGIDAPGVAFYATEFDLEFPQGYDIPLSFSFTNSSTNTSATTPSYRCQLYVNGYQFGKYVYNIGPQDSFPVPEGIWNYQGSNYVAVSLWALEKEGAKVEKLELVAGTPVQSGFGPIELAPQTGWKKREGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USX0</accession>
    <name>A0A9Q8USX0_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_11038</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USX0"/>
    <dbReference type="GeneID" id="71990916"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11038"/>
    <dbReference type="OrthoDB" id="3629888at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="94" mass="10548" checksum="1D874E9FB01B01F5" modified="2023-09-13" version="1">MAASQSDTNPSAQPKSAAMDHPPATDGAKADSKASVLTLPRELRDIIYEYTFSGHEYSIHDKKRDHTTGLLRACQQLRAESITTYYKLTRFRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU55</accession>
    <name>A0A9Q8UU55_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyubiquitin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766937.1">
        <property type="nucleotide sequence ID" value="XM_047911448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU55"/>
    <dbReference type="GeneID" id="71992178"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12300"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
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        <property type="entry name" value="UBQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="118"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="247"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="333" mass="37521" checksum="6CE78CDA478ABD35" modified="2023-09-13" version="1">MSVNITIDLKLPMATVATIQKGGKVNMKDLLSSQVAAQITDAVRALPFQVNAKDQDSSEDSSVARPSKKRRQFAKANTTSPPTSVTRTLRDELAEAEAQRRMWARMQERVEKTGTPGMQMFVKMLTGKTKTFEVHPTTPIREVKTIIEECEGIPLNLQRLIFAGKQLDSGPEDDDFDEQQRLTLADLADQDLQKRKHANKRKEKEVGAPKRKGKKRPASDEHEPRTSKRQLRSDTRARLPSAGTGPMQIFVKTMTLKTIVLNLEPDSSIRKVKQLVREAEGIPYDQQRLVFAGKQLEAPPEDDDDEEREERTLLSYGIQHESTLHLVLRLCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUB8</accession>
    <name>A0A9Q8UUB8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767099.1">
        <property type="nucleotide sequence ID" value="XM_047911454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUB8"/>
    <dbReference type="GeneID" id="71992184"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12306"/>
    <dbReference type="OMA" id="ANAPYMQ"/>
    <dbReference type="OrthoDB" id="4065319at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051009">
        <property type="entry name" value="PRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36089:SF1">
        <property type="entry name" value="CHITIN SYNTHASE 3 COMPLEX PROTEIN CSI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040369349" evidence="3">
        <location>
            <begin position="26"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="407" mass="41411" checksum="65FDDADFE3C0BF54" modified="2023-09-13" version="1">MARHTNLLRACAVVALLAALPAVHAQADLPDLATATDATATTATGATSATDATTGETTGGTSATSTGDTTAESTAESTSDATTTGATSITASFPTGVTTNTAGTTGSIFSLTGLPTIAGAGIPTMVVPYTANAPFMQKSALPEGTVFIAVGAVLAFMGACVLLWRGLVAWSINRSVKRSALASIRGSDKGSQWGGAGAGAGAGNNNAYYKEHDIGSSMSLDALTSNGKNIRNSKVAGDDKRFSSAPPAGLFFSPTAQASNRASSAVYDNRGSTYLPAGYYASPNSELAGGRQSAVIGDSLAPYARHSQISPSPPGTPNSKLPNSRSTANYYGGRGFESGLRSSSREGLRASSQHERHSRLYQQPSTSSLAVGGGSQSSHENLPGMRAPSAVFSDMLENHGQGPRERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV10</accession>
    <name>A0A9Q8UV10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911867.1"/>
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    <dbReference type="Proteomes" id="UP000756132">
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:Delta24-sterol reductase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:FAD binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="167"/>
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        </source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="UJO23514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="512" mass="57939" checksum="D19951F59241DB65" modified="2023-09-13" version="1">MDEHAERVRKIAAAVKGFHETKQKFRIDHGSTNSTRNQRSKGNNVINTSKMNHVLTVDTDKRTILVEPNVPMDRLVEATLAHDLIPLVIMDFPGITAGGGYAGTACESSSFKHGFFSDTVNSIEMVLANGEVVICSKDERKDLFRGSAGAMGSFGVLTLLEIQLEPAKKYVETTYHPVTSFDEAVKMCHDVSTGTSSYDYVDAILFSSTSGAVVTGRCTNDRPVDLPVQRFSASTDPWFYSHVRDRLCTSQEPVTELIPLPEYLFRYDRGGFWAGESIFQGQKGGEGIIPNTKTYKSWLDPLLHTRMLYAAVHSGGFNGQIVQDMTVPYDKAPGFLEWVAKEMEVWPLWLCPVKPSPNPTVHPHKNPVKSNGPQPQMLNIGIWGAPTESEFDYWIDINRQLEAKLREVGGMKWMYGVNLENDEDFWGQHDKEWYDQLRKKYHADWLPSIADKARTTPKKCLEAAETQPWMDHILFNYFPGFVITALVRAWWSGAWKHDRAATWPKWVPRETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVB1</accession>
    <name>A0A9Q8UVB1_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71993189"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13311"/>
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    </dbReference>
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        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="456" mass="51170" checksum="F2A9DCE0E997F25F" modified="2023-09-13" version="1">MASNSSTADDLQDSSDVLARLYDGLHLKCLLQHPSFNHDHAQAVVAQTSDHSRTARSVRQRFLDELCYLCQFRPAGDSIVSIAAERQNRRVILRVSTNERAVQPVILHLCALQRLLEPLCSSDPAQNEKLRDNTLTRIFKASVIQSTTRVQNYHRQLINAIRDMREQYGTLRAPARPSGMNAQDWRTLDSMSCIDLNDGNTRKRNCIDLCVLAHEIRKSDIWNHLDPSGSGPCRARERVRHYIGRLDSWRRAARYVINTAAGPSSPQAPLITAAVSATPSQPTLRGQDAIDVDPDIDGLVLTVCPRYRSDEIRPAVVKKLNNAKSLHKRFVDVRQIPIVHAEAAMAYYFWANSKTFADGELAIGCSKPSCFCCDMYLRILFDGRLLRPTHGNAWFAWYPPSSPVAGYKRHDARTVDIVNRMGSEIQSNVEKCIDKGIFGRDRMHDSTTGTTGTSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVL1</accession>
    <name>A0A9Q8UVL1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768449.1">
        <property type="nucleotide sequence ID" value="XM_047912216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVL1"/>
    <dbReference type="GeneID" id="71992946"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13068"/>
    <dbReference type="OrthoDB" id="76224at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013240">
        <property type="entry name" value="DNA-dir_RNA_pol1_su_RPA34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053263">
        <property type="entry name" value="Euk_RPA34_RNAP_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28155">
        <property type="entry name" value="ACR243WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28155:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34.5-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08208">
        <property type="entry name" value="RNA_polI_A34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="503" mass="54210" checksum="E6354F52EEADAD86" modified="2023-09-13" version="1">MAKDKAAKPSSSKKKDASTTNAKPAKSTNAKPAKSTKATSKSSGLSEERIADSDSDNEPAPVPKKTTPKKPTPKSTTKKESTKKSKAVSPPSSESEESSSAEETTKVVPKKPEGVPPKVNGVKRKAEEEESSGKESRSSDEEAEAEKPQAKKAKTTTTKAASPPSSDEEESSAESEAEKSAAAARAATPKDKQPALAQQQQSSLQSIPAKPFEPPSGYSSFDVEIPDSDSHLSKKNLAGKQIWHITAPSNVPIKTITEVALDAVSNGTPVLNYKDVDYVLDEDTSYDTKFSNVLLPGDAGFQHAGQNVDRTLRLQQKIELPNLSKKQADLNTGSNAAADIAQAPVSDIRPQPKGLKMRYKPPGFGKGDPGMMSGSSDDEGQQSSNKGFQFPKTLGAHGAADEPETALTEKSKKKDKKRRKSENLIDGDVEMVNGDSMPPPSSKKKKKKQEDGLERVVSKESERSQEKEDETPEEKARRREQKRLKKEAKKRAKEGESGLEKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW26</accession>
    <name>A0A9Q8UW26_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768947.1">
        <property type="nucleotide sequence ID" value="XM_047913205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW26"/>
    <dbReference type="GeneID" id="71993935"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14057"/>
    <dbReference type="OrthoDB" id="3650939at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="177"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43934" checksum="19E510D58ABC7641" modified="2023-09-13" version="1">MGSCAGPFTHETRHVTEAPPHFNRAPWSHAHSQRPHLLLLLLHACGNLGTHCTRAAPRAAVHADVVQYQQHAWQEINRPGKYWKLPAFNKRTKPELQHYLTSQNHHFDKSHGKNRLVELCSLCYRGLPSYHSCTIPELEGYVRARRLPVQTGRGRKLDVKKAYLVSALEDADDDLSFERFEDLPAELRLRIYGLHFASFKERIVWTGKFQQPTCHELESKPMSIPSLPPLTEVSRLMRQETLPVFYQTMPSFLHAECSASINRIAEGGHEHDWRYWTSISPSHVNMMRQISLNLCVNPWGGWDATPGKLLLKAGSETKPLSYEFVVEGTKSPDSPTETVRDFADWHEKFEPKMRQIVEDAGNGGQHVLSRDLVDAVLSALRSFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW79</accession>
    <name>A0A9Q8UW79_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769097.1">
        <property type="nucleotide sequence ID" value="XM_047913184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW79"/>
    <dbReference type="GeneID" id="71993914"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14036"/>
    <dbReference type="OrthoDB" id="3553147at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="44"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="327" mass="36755" checksum="FF25AE91C926E84F" modified="2023-09-13" version="1">MLFQWSRLEAGTIRLVRFLPYSTPSNLYLALEHRFGYWEEAVQYKALSYVHGDHTNRKSVTLAGRSFMITANLYAALAAVYARGEGDCWLWVDQLCMNHQNIAEKNSQVAQMGSIYASADKVLAWLRPQDSMLRELATGEAEQNTGRSKCPGHDTAAVLRDIARHPYWHRAWTRVEALRAQSLEIMYGDCFIKHEQLQSLHGSMQVADQEVLRAALQRFLPKPEPGPADDNVHPATILSEVMLEYSKCISSNVLDRIFALLNDPRLDTLPLKHRPQPNYGLTAPGLASALALWHDDLRNVPATSPTSGMNPTLYDFHGCLTAVLDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW85</accession>
    <name>A0A9Q8UW85_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769008.1">
        <property type="nucleotide sequence ID" value="XM_047912584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW85"/>
    <dbReference type="GeneID" id="71993314"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13436"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32949" checksum="F8220EA3AA270991" modified="2023-09-13" version="1">MQNTTIPQSNAFNSAVDSGHFEDLPHEVVELIAGQADGSTLKALRLVNRLVKAIIPKPFAVRLFGNFNIRTTPQDLRNALQLQGDVDFTQYARKIQLWWLKDFKNEDEVAGLLQVLLNKSIGLKSICIRLDRWPSGLSIEQRRHFTSTILRAIQDASLPTFREFNIWGGKIDIGAIQACIEVHKGSLPHFEYTCTMGDHTAWDKCLQTISESRIESLRLEENGHSVPAYLSAVTGRESAGIPPVKLVEVVRAPGSNRIQTYHIFGTCAHLRGREAVRAGIAVILGARGRMTQQTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWH1</accession>
    <name>A0A9Q8UWH1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769410.1">
        <property type="nucleotide sequence ID" value="XM_047913500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWH1"/>
    <dbReference type="GeneID" id="71994230"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14352"/>
    <dbReference type="OrthoDB" id="3638266at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10279" checksum="98A83760D3D122AA" modified="2023-09-13" version="1">MHYLVSVSGGCCVETTTTGTLNTYAASSDSQKWQVYFRHTDLNVQVALQNARDSQWLRAAAGGPNGKIETGERQWWTLEKGKAPNSYWLVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWH8</accession>
    <name>A0A9Q8UWH8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769397.1">
        <property type="nucleotide sequence ID" value="XM_047913645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWH8"/>
    <dbReference type="GeneID" id="71994375"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14497"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="26148" checksum="42B46CFA98836890" modified="2023-09-13" version="1">MHGPIQALLELVEELIAETPKDVDSKTVLTEQSIRLLLDPTDLTASQLGLRQNDFPTVHDIKYISHLLTTAPPQHLLALLLGHNEAQKTLREVLTPVELSRVDQATYARLQILKRQSVSVSDALGRRLSATKENYRMMKATMKQFVKTAGVASVLDETARESLIALLWDDLVGVEDALNALEVEEAQREVRALMVKLDAILAKVLFVGCDVAGLKDCQFRWVVEMRGMGREVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWT6</accession>
    <name>A0A9Q8UWT6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769755.1">
        <property type="nucleotide sequence ID" value="XM_047913488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWT6"/>
    <dbReference type="GeneID" id="71994218"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14340"/>
    <dbReference type="OrthoDB" id="408760at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27393" checksum="960F1095C32FB821" modified="2023-09-13" version="1">MDTPKQPANLAPPTKPSLLRHHQDHLRILAFGNSLTEGYTDFGMRFHPYGNALKSKLSALAPDLTISVDINGQSGDCVLDSLQPTTQRDRIKRAWQYLAIVLGGTNDLAHKLERGLEGSEEIFQGLRPLYEHVLNAGTSLIVMTVPERAIDTRSSDLAVKAHANREHLNRLIVQWAADSRLHREQIDGPKVYFFDLAALVPFPRNEDDGDTTPAEGGMWSLDDLHMTSRGYDFVGNELAAFIKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-04-03" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>L7YER9</accession>
    <name>L7YER9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2 19">Avr9</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Race specific elicitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">avr9</name>
        <name evidence="11" type="synonym">Avr9</name>
        <name evidence="19" type="ORF">CLAFUR5_09818</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2012-11" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">ALH</strain>
            <strain evidence="3">CH6</strain>
            <strain evidence="4">COA</strain>
            <strain evidence="5">ELH</strain>
            <strain evidence="6">EMP</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>Development of a real-time PCR assay for the identification of races of Passalora fulva.</title>
            <authorList>
                <person name="Li S."/>
                <person name="Xu X.Y."/>
                <person name="Li J.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race 2.5</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2014-11" db="EMBL/GenBank/DDBJ databases">
            <title>A diagnostic PCR reaction for the identification of races of Passalora fulva (Braun et al. 2003) [syn Cladosporium fulvum].</title>
            <authorList>
                <person name="Medina R."/>
                <person name="Lopez S.M.Y."/>
                <person name="Franco M.E.E."/>
                <person name="De Wit P."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CK813</strain>
            <strain evidence="10">COM</strain>
            <strain evidence="9">ELS</strain>
        </source>
    </reference>
    <reference evidence="11" key="4">
        <citation type="submission" date="2018-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Lucentini C.G."/>
                <person name="Medina R."/>
                <person name="Franco M.E."/>
                <person name="Saparrat M.C."/>
                <person name="Balatti P.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CIDEFI322</strain>
            <strain evidence="12">CIDEFI323</strain>
            <strain evidence="13">CIDEFI325</strain>
            <strain evidence="14">CIDEFI326</strain>
            <strain evidence="15">CIDEFI327</strain>
            <strain evidence="16">CIDEFI329</strain>
            <strain evidence="17">CIDEFI330</strain>
            <strain evidence="18">CIDEFI332</strain>
        </source>
    </reference>
    <reference evidence="19" key="5">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="19" key="6">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KC132836">
        <property type="protein sequence ID" value="AGD98918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132837">
        <property type="protein sequence ID" value="AGD98919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132838">
        <property type="protein sequence ID" value="AGD98920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132839">
        <property type="protein sequence ID" value="AGD98921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KC132840">
        <property type="protein sequence ID" value="AGD98922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KM880022">
        <property type="protein sequence ID" value="AJF35004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234076">
        <property type="protein sequence ID" value="AKF40397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234077">
        <property type="protein sequence ID" value="AKF40398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="KP234078">
        <property type="protein sequence ID" value="AKF40399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308690">
        <property type="protein sequence ID" value="QDM02409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308691">
        <property type="protein sequence ID" value="QDM02410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308692">
        <property type="protein sequence ID" value="QDM02411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308693">
        <property type="protein sequence ID" value="QDM02412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308694">
        <property type="protein sequence ID" value="QDM02413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308695">
        <property type="protein sequence ID" value="QDM02414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308696">
        <property type="protein sequence ID" value="QDM02415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MK308697">
        <property type="protein sequence ID" value="QDM02416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="L7YER9"/>
    <dbReference type="KEGG" id="ag:AAA03344"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007688115" evidence="1">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AGD98918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AGD98919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AGD98920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AGD98921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AGD98922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AJF35004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AKF40397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AKF40398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AKF40399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDM02409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDM02410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDM02411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDM02412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDM02413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDM02414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDM02415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QDM02416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="UJO20306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="63" mass="6741" checksum="E4E330FD68F6D5AA" modified="2013-04-03" version="1">MKLSLLSVELALLIATTLPLCWAAALPVGLGVGLDYCNSSCTRAFDCLGQCGRCDFHKLQCVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXW2</accession>
    <name>A0A1P8YXW2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_04525</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943190">
        <property type="protein sequence ID" value="AQA29361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760331.1">
        <property type="nucleotide sequence ID" value="XM_047903673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXW2"/>
    <dbReference type="GeneID" id="71984403"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04525"/>
    <dbReference type="OMA" id="SMAFELT"/>
    <dbReference type="OrthoDB" id="3642826at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671820" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQA29361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1195" mass="120563" checksum="092BA1EE542CE7CB" modified="2017-04-12" version="1">MVPWTAVVTLASLSGSAVADHIYRDPVRGPYGIPRQPRQFQAEAPFPLSSGSRRTFSSGSLPSPESSSAVPSSSTSSSTTARFNPITVASVTAPATPTPTSRLSTAVLPILTTAASSVPKYTYDPVASSSYTPSQYGSSGTAAPVRPSGRPRPPRNGTCSGATVNVLGASLDWWYSETYTQVESTFLVQFAENNTATGWTLLPAETTFDVTSAVANPTCNSVTAFNSLANETQLHYTCWETPTPVAAATTTVEQTAFKPINGTSSTGTVPDIVTTPTPAALSIGKSNETVAAGKSIVHFSQYEIVSKRSNRRYDGQVECFETTTTHQLNKTHSFEYKGRNLDSPAATDEGVVGKLQLAFLQAVGQATATPGTWVAEPTVVVLVEKIAAAQAVLAKGFVEQPADALRTITPTLPPGLSTLRTTPTEEGTFWVPLTARIESSADALDVPTRTKATKTPAKNDATPTDEDVSIGVPFIAHVENSAVTLKIPVNPTRPHSVVTAIWDGKTVTATALPIKVGSDDDDDIDRIVSAVVDAATPKNALDVLKQAQQTASRGGRVESSNSPASAIAAIIGAVPGSSTSGGSDGAVGSPGGLGNTNGQSSHGQVGASGPAAGGQNNGDSGVIGHIANGSNGQGSGSAVHPGEQSSNGEGESSESQDGDTDPGSSEHSPSGGQAQATQGADMGTNGNSRPVLNIGGSTVTGTFVGDQTAPAMIIEGQTAVAGGQAITIDGKRVAVLPGAAAIVVDGSTMHFAAITADPGALANIPLVTIDGNVFTANAATQFNIAGSTLTPGGQVVVSSTTISLAPDASQIIVGGQTRELSPPVITPAPLLTLDGTVYKPNQGSTYNVNGQLLAPGGAVIVSGTTVSLASDGTNIFVDGSRQLSTGAGGQGINLETITAPPMLAVDGQAYSPNGGTSYIISGQTLTPGGAITFDGPAGLQTISLNDNANQVVSIANGVSGTSTIGMIGAAASGAPILTIDRETYTAVGYSPGSGARYVVSGQTLTPGGSITLSGNDGVTTISLVPAGTAVITISDGTTSTSKIAGAYGVLPTNAPVLTIGGETFTAVNNGATYNIHGDILTPGGTDTVVIGGQTYVVTLSPYATLLEVQVVGSDGKTTSTLLETLFPATMAGSTFYNPAFTDGAAATAGASRTDGSASPTEMNTAYSSNRGSSSMAFELTATIIMLSSLVLALWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5F5</accession>
    <name>A0A9Q8L5F5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755508.1">
        <property type="nucleotide sequence ID" value="XM_047900656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5F5"/>
    <dbReference type="GeneID" id="71981386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01508"/>
    <dbReference type="OrthoDB" id="2851338at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="232" mass="26918" checksum="C5B9C61371B78BF2" modified="2023-09-13" version="1">MAPVLMFVGSSIIDGAKTSDEKYNRVYNEEHLPAILAFDNANFTKLALRYKNAYPDAKLPYLALYPVDDAEMLDPELMQRLIAEITTSQTFDGDDVNDHTQFGLTRYEKIQTYEAYQQENRSGKDRAETIVCVAMEPKDDVEFDEWYRKQHLDMMGMCKGYRRCTRYQRTDGQSPRFLALHEYACKPEELPGEQIKQVTQTEWSKKTVGESKVFERNVFHLIQAQGNTELNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5L2</accession>
    <name>A0A9Q8L5L2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_01044</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755667.1">
        <property type="nucleotide sequence ID" value="XM_047900192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5L2"/>
    <dbReference type="GeneID" id="71980922"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01044"/>
    <dbReference type="OMA" id="IKGRSEM"/>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000001">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="35"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="209"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO11301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="40715" checksum="1312F40697149E4B" modified="2023-09-13" version="1">MSSTEGKTITCKAAVAWEAGKDLVIEDIEVAAPRAGEVRIEVYYTGVCHTDAYMLSGKDPEGAFPVIAGHEGAGIVESVGEGVTNVKKGDTVVALYTPECGECKFCKSGKTNLCGKIRATQGKGVMPDGTSRFKCKGKDLLHFMGCSTFSQYTVVADISVVAVTDKAPMDRTCLLGCGITTGYGAAVITAGRGGVEKGANVAVFGAGCVGLSVMQGAAARQAGKIIAVDVNDAKKDWSKQFGATDFVNPAKDLKEGESIQQRLIDMTDGGCDYTFDCTGNVSVMRAALEACHKGWGESIIIGVAAAGQEISTRPFQLVTGRVWKGCAFGGVKGRSQMGGLIDDYMSGKLKVDEFITHRQPLSKVNEAFHDMHAGDCIRCVVDMRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6E7</accession>
    <name>A0A9Q8L6E7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756018.1">
        <property type="nucleotide sequence ID" value="XM_047900507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6E7"/>
    <dbReference type="GeneID" id="71981237"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01359"/>
    <dbReference type="OrthoDB" id="4085451at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054448">
        <property type="entry name" value="HTH_put_ascomycetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22943">
        <property type="entry name" value="HTH_68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helix-turn-helix" evidence="2">
        <location>
            <begin position="185"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="244" mass="26060" checksum="EF3D8287FA24A2D5" modified="2023-09-13" version="1">MLLTDPSIIDINISYPSTQRLSIHVHVAIATSAAMGSSASKTAKAAGSAARQYPNRPSGTTQRPAPTTTTNAPPPPPPPPAAQRQPGPTVKPQPYASGDRSEAINLDASDPDFAQSLRSIGPVQPNPTLSPTSAFTTQPGGARPHAPNPRNNPAITVLHSRAKLQEAADAEFEQAGIRGHQGRQFLDVYQIRQILQFRDERGMKHSEIERRLGLKEGAVARLGAAGVVELAQEQGRAERDIRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6I1</accession>
    <name>A0A9Q8L6I1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">acetylglutamate kinase</fullName>
            <ecNumber evidence="6">2.7.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_00685</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 19">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 19">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">In the C-terminal section; belongs to the NAGSA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">In the N-terminal section; belongs to the acetylglutamate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="6"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756078.1">
        <property type="nucleotide sequence ID" value="XM_047899833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6I1"/>
    <dbReference type="GeneID" id="71980563"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00685"/>
    <dbReference type="OMA" id="IAFIPHV"/>
    <dbReference type="OrthoDB" id="438291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04252">
        <property type="entry name" value="AAK_NAGK-fArgBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23936">
        <property type="entry name" value="AGPR_C_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24149">
        <property type="entry name" value="AGPR_N_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04263">
        <property type="entry name" value="DUF619-NAGK-FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000019">
        <property type="entry name" value="Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000029">
        <property type="entry name" value="Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000046">
        <property type="entry name" value="N-acetylglutamate kinase / N-acetylglutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058924">
        <property type="entry name" value="AGPR_dimerisation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041734">
        <property type="entry name" value="NAGK-fArgBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011241">
        <property type="entry name" value="NAGK/NAGSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22698">
        <property type="entry name" value="Semialdhyde_dhC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036440">
        <property type="entry name" value="ARG5-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 19" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="12 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="16 19" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17 19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13 19" id="KW-0521">NADP</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="21">
        <location>
            <begin position="342"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="active site" evidence="20">
        <location>
            <position position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR036440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO11712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="891" mass="99021" checksum="C4DCDBE6EAD4E17E" modified="2023-09-13" version="1">MQSIARPLCRQVLRQQRRVIAKQSSTALAVSVSRPAVQRVQQYATSHRSDESSARSAVINVLNNIASKREVQQYLAQFTSVSSQQFAVIKVGGAILTDYIDVLCASLRNLNQMGLYPVIIHGAGPQLNKMLEEAGIEPRYNEGIRITDGKTLGVARKLFLQENLKLVEALESWGVRARPITSGVLLADYKDKDVYEFVGEVNQVNAQSIKASIADGYIPVLTCMAENDEGQVLNVNADKAAAMLARELQPLKIVYLSEKGGIHDKETGKLIEAINLDEEYDDYMKKSWVIHGTRSKIRDIKTLLDDLPRSSSVAIIHPESLERELFTHPGAGTLIRRGTKLQQASSLREFENIEQLKQTLLRDREGLDAANVVDRYLEILESRPFKAYYDENMEALAIVLPPEGSSDSMGHLATLTMTRNAWLSNVADNVFQNLIRDFPKLAWTVKQDDENLTWFSEKADGSIARRGEVLFWYGIDTPEEVRELMAEFIQHGRKMFGDINLESQLHRAASAAERIRSRAAELAKGRQPQSRAFGTSVRPTKRVRLDGLQQVRTYTTNPNPPLGIKNSEKDYPAKVAVIGARGYTGKALIDLLNRHPNMDLCHVSSRELAGKKLQGYEKKEIIYESLTPDDVRKMAEKKQIDCWVMALPNGVCKPYVDAIEESGHKEAVIVDLSADYRFNSEWTYGLPELVQRNKIASATRISNPGCYATAAQLGIAPLVPHLAAAPANPTVFGVSGYSGAGTKPSPKNDVQVLTDNLIAYSLTDHIHEREISTQLGREIGFIPHVAVWFQGIHHTISLPLAEKMASRDVRQLYQDRYDKEKLIKITGESPQVKHIAGKHGVEIGGFAVHSSGKRAVINVTIDNLLKGAATQCLQNMNLALGYAEYEGIPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6K5</accession>
    <name>A0A9Q8L6K5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Surfeit locus protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00756</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756129.1">
        <property type="nucleotide sequence ID" value="XM_047899904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6K5"/>
    <dbReference type="GeneID" id="71980634"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00756"/>
    <dbReference type="OMA" id="RHRHFPW"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L718</accession>
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        </citation>
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        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="447" mass="48385" checksum="C8F73ABB6BE4FA8E" modified="2023-09-13" version="1">MLPMPGAPSSSWRLFVSRLNSKFENASIRVCLAFWLFGLINNVFYVIILTAALDLVGPSIPKATVLLACIVPGLATKIVTPYVIHLIPYSVRTVIFALLSTCGMLAVALSPNTTDAFSLSSKLAGIVVANISSGAGEVNFLSLTHYYGHLSLAAWGSGTGAAGLIGAGAYTLATTTFGVSVHATLLSSTVLSVVMLGSYFMLLPLAPLKGARRKERGYEQVDREEDVAATEHPESAGLLAQSAARSASPAYGQHHTWMARAWIDLKAKLVRAKGLVVPYMVPLFLVYLAEYTINQGVAPTLLFPLDESPFKHYRAFYPTYGTIYQVGVFISRSSLPFIRIRSLYTPTFLQVLNLVALAGHALFPFIPTVWFVFVVILWEGLLGGLVYVSTFAAIREDIADEEREFSLGAVTVSDSAGIFFAGLLGAGMETALCNWQVNHGRDWCRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L850</accession>
    <name>A0A9Q8L850_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756984.1">
        <property type="nucleotide sequence ID" value="XM_047900278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L850"/>
    <dbReference type="GeneID" id="71981008"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01130"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF2">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="807" mass="93271" checksum="E878009D78BC2726" modified="2023-09-13" version="1">MLQIHARCRPANSAKADARDFSTSIFKDWTSLNALLKRFELVVQRRWMKKSSKQRLELLLKAWPRMSPTHRPDLSNFRDMQKQASREKTCRSEAYLWPHINLEDLQQRNFLLLFLNSRGRNLPETFRLADIKSAHLGNSWLPDLDLATEACLEGYCCEDHYLADSTGHEPHRMMFEKRHSPNGYGFVLDCRSVRLKSGQHKHLSRCQEGLLALEIQQETYRFLLASAKLILHDIEPSMFFLAPHRPEPSVPQLAKRNEWASLAGHTIQAPYCIPQRLDLQRLRGLAIARRSSAEDHVWMLREDPGFFMTTLREWIEHNGTCGCSTVCASSACWKREAGNMSTNAFVSFVLWDDIYRKLKAMPDIEIQMQRADEKHVRLAAKDEDMWMALMDILYNATMFSIDVLREGVPTSPRLRSRYYWRTFAEAQGRWELRTGAPWPVRRVDQLFYSIFTPSQRSLHGLNGLVQETQYMLETETEASHYFDGWITEHFSDLALLSELQHSVDALAPWFDKNKAARFTSQADQLVSRTRGLTAKLHGAIPLVCDELTIAWDHAYTASFDYPAEKAPTKANVDQMRSAERCLDKFWSQVQKRVSSMVKISLEKVLFNRMFESRQLYRTPPWQKPVQPPTPECTPPKTTVTADPPSATLQHTSAGSQESAEVTLTRGKQKIKTRGQPAAPDPRMIIADDAVVAQHRVKLPKEVHKVFCALLPSTVDVAQQRFEIGWEEMLFAFDHIGLEPEQLHGSAWIFRPRPREECKVELRRSIQFHEPKELRRGAKIPRPMVRLYGRRLKHAYGWTCAEDLFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L864</accession>
    <name>A0A9Q8L864_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal targeting signal receptor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_02003</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756946.1">
        <property type="nucleotide sequence ID" value="XM_047901151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L864"/>
    <dbReference type="GeneID" id="71981881"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02003"/>
    <dbReference type="OMA" id="WEEQFKQ"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000218">
        <property type="entry name" value="Peroxisomal targeting signal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="9 15" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="332"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO12580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="626" mass="70032" checksum="4539F723202E5C99" modified="2023-09-13" version="1">MSFLGGPECSTGSNPLAQFQKTTGADTSLQRDRLTSRQPQQFNGFRSGQQVPDDAAFQDFAQQGPHMGDMLPNDAFHMEQMRREAEHLERANGGGSAGNANWAGEFQQQGPRFAPEEFQQQQRAGGFSPQEFAQFRQSQMTPTARTQSPSFQQQSAYRPPMYSGGFGMQRPMMGYQGSMMQNGMPQQYEGKGKGRVQELSDTDWEKQFEELSTADQEADQLDQEAEEAVERQLNQLDKDMLADDEMAGHFGDEFDQWKDFDGLNHNFDSFRNEFGDYSTAPNQGNYMFEENNLFKDVPNAFEEGMKIMREGGNLSLAALAFEAAVQKQQDFTDAWVALGQAQAQNEKESPAIRALEQALKIDPSNLEALMGLAVSYTNEGYDTLAYRTLERWVASKYPQLGVTPRGIEDEEEMGFTDRHMLHEKVTNYFLEAAQLNPEGGDVDVDVQVGLGVLFYGSEDYDKAVDCFTAALNSHQHGSMKREGEEHLLWNRLGATLANSSRSEEAIEAYSRALELRPNFVRARYNLGVSCINLGVLEEAAGHLLGALSMHKLQEQEGRAKAAEILKDGHGNDIDEQAAVDAALHQNQSTNLYDTLRRVFTQMGRRDLSATVGPDMDLNQLRGQFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8D0</accession>
    <name>A0A9Q8L8D0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">INO80 complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_00755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756419.1">
        <property type="nucleotide sequence ID" value="XM_047899903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8D0"/>
    <dbReference type="GeneID" id="71980633"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00755"/>
    <dbReference type="OMA" id="QEQVTVC"/>
    <dbReference type="OrthoDB" id="3214149at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000201">
        <property type="entry name" value="C2H2 finger domain protein (Gli3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="199"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="295"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO12053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="52805" checksum="3D002E37454D86C1" modified="2023-09-13" version="1">MADSPPSSDLSDPPSAESDNEDQLSTAGPSSRPSVDISHLDIEHLAPPAKRRKTGPSSLGLDRAPSSQPEQDDDNESISSDSWSSAPGSPNDDEYNLRDQAQTQCLWRDCEFGLANNNDDLVRHVQGTHCATGGPKKTKYVCEWGECQRKTSNHPSGYALKAHMRSHTKEKPYYCALPECDKAFTRSDALAKHMRTVHEPEAAKGGPGHAHEPTPPGKKSLKLKLNGSTTSKAPADMGPTHDEDGNEVDPSPPNDNITYMPAHHPITGQPGFMIHYPPDIHFTAWESSIAADQLMRLLRRQLHWAQKEADDLKKQVDDLEAQKREEWTLKEILLDGFLEQELAQAERADILQNVDQRVRDAMERDIEPAKQLAWTGGEPHWRRPNSLPLQRDVGINLSTPDRAGLQHSTSPPPTGMSGGFDGEADPYDNYIAGRIAEFEAREKMRSMQNTPAEVTQEQQQAAEADAVGALMGMSNGQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8N9</accession>
    <name>A0A9Q8L8N9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757187.1">
        <property type="nucleotide sequence ID" value="XM_047899605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8N9"/>
    <dbReference type="GeneID" id="71980335"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00457"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="365" mass="39658" checksum="32F55B3BCA43AE97" modified="2023-09-13" version="1">MAPYTNIPLSPAELSYLHHSLSQTPPIRPDGRAPTQFRPLVAETEILPSANGSARICFADGTEAIVGVKMEVEKTVLVGRGGLHVQREQERGERRVDGDVDMDGDGEYEEGRGEGRDEWLEVAIEIPGMRDDDALPVFLAAMLTEAMLADGSGVRDRLWINGRFHWRLFVDILLLSQPLSYPLPLLSLTTHLALLSTRIPALISERDEDPIFNDDWEASTYLFPRDDASGKSTTKPPITLLVMTAGSNILFDPSKEELAVADAVVAISAAAQGQDRQMKMVALRTVDPPSRLTAAGVPNRADTTAGGGMSAEETLKLREKDAGQSVWRPPRGGVSRTLLAQMIKAVVERGGVGREVMEGLNAVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L944</accession>
    <name>A0A9Q8L944_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00327</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756839.1">
        <property type="nucleotide sequence ID" value="XM_047899475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L944"/>
    <dbReference type="GeneID" id="71980205"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00327"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="74"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="598" mass="68189" checksum="DD29E84C0DD235E1" modified="2023-09-13" version="1">MSALKDKADWQRKVFDESIVGKWRLEALQFSAARKPESADEVVTNAWKKTEDSGENGESLDLDGEQRQTIISQAVFDYCIAELRDNAKQDRQRGFTQAIDANACVFMSDSAIPSATKTALQQAAARLEDVKAHQKDWHPGSDGKVLDLVHPSLFPLLYGRSRMMPTGAVPTEKCAWYTGRGSIVPEADIQDTDYSDHFQWLPCDVATSDNGRAKISSYINNLYPHGNMDLYAAIEDVITASVPLWTETLLSTQFLATHRIKDDFGDGRIEKPRPSRRSDEDDAHYDDWHNAYDAAIPEPKTYALRQRVQPKVFVPDDPNYKDPGQKTAATKGWRLSDIDQPLKNPSIEPSQEQIAEGDAAMEEERKRLQNVFQKQGMQVIVKLANIHLTPDRPTYDGGSWHIEGQLNEHIAASALYYYDTENITDSYLAFREGVDKDELNDYEQSECYALMEIYGIRNYWGNAIQVLGMTNTREDRLLVFPNVLQHRVSPFELKDKAKPGHRKLLALFLVDPFIRIPSTSNVPPQQREWWARAMEEKGTLSQKLPMELVDQIIEDVEDFPITLEEAKELRGQLIEERKVYVNDSMQPYQNDGYCFCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L974</accession>
    <name>A0A9Q8L974_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_02512</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757617.1">
        <property type="nucleotide sequence ID" value="XM_047901660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L974"/>
    <dbReference type="GeneID" id="71982390"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02512"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000741">
        <property type="entry name" value="Putative mitochondrial dynamin GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13 17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="19">
        <location>
            <begin position="260"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="926"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO13251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="950" mass="105172" checksum="2E8934B0012F7C0A" modified="2023-09-13" version="1">MISRLRSSRLVSSAQRTSTTLARPTSHNVASIYSSSTLAAKRSVSLVALSGSRTTLRRWQQRNAWPMGANGIHNLPAVRHASFARVIPQLAMKLIRIPAMFGAAMIGGMAYLQYQAAQGWTWATKALGEAKDTASSTANSLYDGFGSVFGQIGKGFDKTKDEVKRVQMPQWMKDIYEGRAGQEEGGEGGSGGPNEPKESGTRAGTAAAGAATAGAFALDSEGEEDTRPDDVAARDDQMMLLTRKMIEIRSLLQTVDQGDTLTLPSIVVVGSQSSGKSSVLEAIVGHEFLPKGSNMVTRRPIELTLVNTPKAHAEYGEFPALGLGRITDFSNIQKTLTDLNLAVPETECVSDDPIQLRIYSPNVPDLSLIDLPGYIQVEAFDQPTELRTRIQELCDKYIQPPNVILAISAADVDLANSTALRAARRVDPRGERTIGVVTKMDLVDPKRGAQILSDKNYPLRLGYVGVVCKVPQESRSLFSRGSASITSLITKNEKAFFGAHPEIYGSDAQSNVTVGTPALRKKLMHVLESTMSASLESTSEAIQHELAEASYEFKVQYNERPLNAESYLAESLDAFKHGFKRYSETFGKAEVREIVKHELDQQVLNLLAQKYWNRPVEDLRPMEQSAEGVLEPLENLPKADPENPLWHLKLDASTSTLTKLGIGRLATTVTAQALQSAVQELIYSTPFSTHPFAVSAITQASENILRDLSYDTSDELEICVKPYKYRVEVNDYEWKQGRENITRVLKDELKDCETAFKAVEDQIGGRRKAKDVLAFIDRLRKGEIVLEGNGVGGAGGFSAALLEKGKQALFLRDRSDILRMRLAAVKSKQCAQPKNKYYCPEVFLDAVADKLTSTADLFLDAELLSKFYYQFPRVLEKWGRELDESTIERFAREDPKIRRHLDVVKRKGLLEHVLKEMESLRLLEAREKRQSSRGTQTEEGARRRKGWGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L979</accession>
    <name>A0A9Q8L979_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxypeptidase S1 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03367</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757457.1">
        <property type="nucleotide sequence ID" value="XM_047902515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L979"/>
    <dbReference type="GeneID" id="71983245"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03367"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF64">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040469358" evidence="7">
        <location>
            <begin position="23"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="583"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="583"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO13091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="629" mass="69200" checksum="BDE87C6C79A466C1" modified="2023-09-13" version="1">MASILRASALYMYLALAAPTFAQFVKAPTDLTTTKGNLDLPVRWKEVPEGTCELTPGVKSYSGYVDIENNQHIFFWFFEARDQKPEDAELTVWINGGPGSSSMIGLFEELGPCRVDMDGNVYHNPYAWNNVSNMLFIDHPAQVGFSYSTPIPSYISSAGSVVQLPNATCPEYAADVDCATRSQPKQTDTANSTSNAAPSMWKTIQGFMGAFPQYSRTEFNFATESYGMYSSTDEIERATAHPREPHISLVPNFFFFKGGHYGPIFNAYIESQNKLIDDGSLPGAKHINLRTVLIGNGWYDPLIQYQAYYNFTVYPGNTYDYRPYNSSVEEQIYNALYGPGNCYDQTVACNTGGLNEICMAADSFCANEIEVPLGNEGRDEYDIRELTPDPFPYSFYSKYLNSPKLQQAIGAYVNFTSSNGAVGDAFSSTGDDDREDGTIEATRSLVEQGIYVVQFAGDADYNCNWLGGEVIAHEVDAPGFGTAGYTNITTSDNIVHGQVKQSSNFAFARIYESGHEVPFYQPLIALEMFNRSIHGLDIATGEKEITLGCGYKSVGTAKSEYREGNGTVQFKVLPANATYNTTLNGPNPINGTSSAGGDAASKKRGMMTRAKQSLKSKRTFKPSFGRKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA07</accession>
    <name>A0A9Q8LA07_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Post-transcriptional regulator MKT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPG/RAD2 endonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757930.1">
        <property type="nucleotide sequence ID" value="XM_047901769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA07"/>
    <dbReference type="GeneID" id="71982499"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02621"/>
    <dbReference type="OMA" id="RFYQTKV"/>
    <dbReference type="OrthoDB" id="17262at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09858">
        <property type="entry name" value="PIN_MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022039">
        <property type="entry name" value="MKT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022040">
        <property type="entry name" value="MKT1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF32">
        <property type="entry name" value="POST-TRANSCRIPTIONAL REGULATOR MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12246">
        <property type="entry name" value="MKT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12247">
        <property type="entry name" value="MKT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="XPG-I" evidence="3">
        <location>
            <begin position="147"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="736" mass="82018" checksum="8435488E2DC9EC6C" modified="2023-09-13" version="1">MADNSTFKDWALSQGFVQKADLDDFRGTTIGIDAEDYLYTLLAEQPTREPLLPAIGGAPFALQQHVDRDLDEMASAGIKAIFVFNGLELGCKDRKSISRECQKASRVLDEAWKIYDEGHGDPAVALFGKTCAYRTAHITRYLHFYLHKKGQQVMVAPYNAAAQMVVLEQNQHVNALHGSASTLVFGVERVITKLDWTDRKVLFVDREQILGKLGLSQPQLVDLLLLSGASIIAEMPELDAENAIPKIQSAKNILSRFGFDGHAACANAKDEDYLDTFRRGKVAVRNMVVAQPNGEIIQLDHENAPSNDHDCIGQRLPEELLAYHQFGLIGSRILNWRTRQEIFETPPLDGGDSAIYKELLREKLQPRRAKALAILTSSLHRYYQKHDVDLICWFNEAEKRPLGIPDSNISTRDIDNWHVKEAQILASPHAKQIDATATPLQYAIALISDDTFAKSTVTPRPSGDDKKLTTPLELLCNTMWRFLQERGYINSNHTLAARGRMLQAAFEHASTSGRLGQGNPANEMEEAIFIAFELLTMELLNPKLLFPRPPYTGEPHRGSEKDKANVRLISRVACLGSFQHQAIGYTGPLSRHLLAYHQVASAVRGSLRDLAEVHGAHMFLSGSAVRKRHRDDFTDLGSRLPFSKEPDVGLAIVLKSYLDEMSNDPSRRQDIKKWFGFALDIDGDLQKAFDLWAAVNAGIQAADTAVVSPETRDLFANADQWLKDKIKNSGHVNGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAL8</accession>
    <name>A0A9Q8LAL8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent clpX-like chaperone, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03697</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758223.1">
        <property type="nucleotide sequence ID" value="XM_047902845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAL8"/>
    <dbReference type="GeneID" id="71983575"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03697"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000138">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="185"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="462"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="67970" checksum="BD71D16C769D42DA" modified="2023-09-13" version="1">MAPVSASTFAPQARLTYLGVSAIIRRQLSTSRHRLDSGSYTRSDFSNQGYTGYYEPREPTEGPLKDASNIGTPRITPTILKQHLDQFVVGQERAKKTLATAVYNHYQRIQELQRRDEEEEEHVAQEERRRMSQHPRHPVEDEFPGQQQTTINLGPPNDSQYPRPLQHNGLGPPPPLHDPSHLSIEKSNVLLLGPSGVGKTLMAKTLARVLEVPFSISDCTPFTQAGYIGEDADVCVQRLLAAANYDVTRAERGIICLDEIDKIATARVSHGKDVSGEGVQQALLKIIEGTTLQIQAKQERGSGAGTDRNQGRGAGYPTNSPLSGGNINQQSPAQKGEVYNVRTDNILFICAGAFNGLHKMVLDRISKGSIGFGATVRAAPDSEGSGNHHETILEGGDDLFEKHLPYYMPPAQPEATATASGKKKPKRTFNTLDLVEPQDIQKYGLIPELVGRIPLSCALSSLDVPALVKVLTEPRNSLLKQYQQLFSLSSIELRFTTPALYAIATTASKMGTGARGLRTVMERLLADAMYETPGSGIRYVLINEDVAERKAGAVYFARGQQLQFRDMIAAEEDAWEERKRREEGEENDFEARARVNSEGGAARTFEEYREKATAAGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAM5</accession>
    <name>A0A9Q8LAM5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758238.1">
        <property type="nucleotide sequence ID" value="XM_047902497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAM5"/>
    <dbReference type="GeneID" id="71983227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03349"/>
    <dbReference type="OMA" id="WAKRIST"/>
    <dbReference type="OrthoDB" id="10491405at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="39711" checksum="B0D1DCEE7B6CC525" modified="2023-09-13" version="1">MAHESWATTSSASTMELPTRPPTGLLFRDSVKGDKSRSWAKRISTFSRRSGRVGPPTPAAVDLEAARNADANTWEPFDEPGDHLRSPPRQEHPMPVLPEAEEDAYWRDGLRDWIAAQPPLVEGDQPATTLPIPGPQPFDQPSALTPSPIGLGISLPPGVHFATPPYPTYHEDMTGIPTRPMYAGTITSSAIESIYDAYTEAARPPYQPDGSTGRRCTHLRCSGAPQSHRTDLPSASSTASSVADFEKTNISPPSHPATGLNAIPIATSRGLSDLEKLNIRGFPSPGPSSDEHSDTAAAPRSTVHITSKSKLCQARLYRRRRRRLVIITLSVLALVCMLSGVVAALVTAGRKDIDTDAARKEVGFGVSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAQ8</accession>
    <name>A0A9Q8LAQ8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_03027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758412.1">
        <property type="nucleotide sequence ID" value="XM_047902175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAQ8"/>
    <dbReference type="GeneID" id="71982905"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03027"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF14">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="45"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43269" checksum="55317CBC287B54F9" modified="2023-09-13" version="1">MTAEKSIARSDISPPPSSKRRKLAPSQTSEDLPQCIDPSRLTIYSWNINGISPFVQKTITSFFQPRNVAHGCESSASPSSSLRDVLRRYEWPAMLLLQEVKINPDDTATQRAVERAVNPITDEPGLPSYRVFFCLPSDKHNARGSGRKVYGVCNIIRQDFFDRYVERVREVSWDLEGRFLVCETKPCGLLPKLAIFTVYAANGTDNPYKDPESGQIVGTWHDRKLQVHELLETECRALEARGVQVVLAGDMNIARMKLDGHPNLRTTPEQHCVNRADFERRFFASGAGSKEECGATGALSGGGLNMIDSWRHFYPRKAGYTYYGRSRPFGSSCDRVDMILLSRAMEDRLVNAGIHETLADRGPSDHVPLFVELQTQLERVDVVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB50</accession>
    <name>A0A9Q8LB50_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rpb7-binding protein seb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03436</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758622.1">
        <property type="nucleotide sequence ID" value="XM_047902584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB50"/>
    <dbReference type="GeneID" id="71983314"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03436"/>
    <dbReference type="OMA" id="GIVQTCI"/>
    <dbReference type="OrthoDB" id="79367at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031126">
        <property type="term" value="P:sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16984">
        <property type="entry name" value="CID_Nrd1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000026">
        <property type="entry name" value="RNA binding protein Nrd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000397">
        <property type="entry name" value="RNA binding protein Nrd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048892">
        <property type="entry name" value="Nrd1_Seb1_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nrd1-Seb1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="8">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="539"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="673"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
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            <end position="343"/>
        </location>
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            <end position="376"/>
        </location>
    </feature>
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        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
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            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="770" mass="81641" checksum="9FA70CF13215E696" modified="2023-09-13" version="1">MATPNVNDLDGLLSSLNQLKPPGASKNKIATITQICVSNIQAESTIVQVFYRALKKAPATHKLGALYVIDSVVRQWIDAAKKNGQNLHIEGRGEMGSYPAAVKRVTELMPVLFDDIMRAIPEDQKPKLANMITIWERGSTFPPHLIAELKAKLSGAPPQAAAAPAPAPPAPAPAPPAVNGNTGHSTTQRPSTEKFMAPIPTRTVQTPVGYPPAHLYEQGFLRMPQGATQPPQIQANGHAPQPVPAPSQPQATQPLPVPGADLHSIMAALQKGVPPPAPTPTFPPAAQSAAPPPGFPAGLPAGLPPQLAALFSQQTLGQQATPVQAPVPPPFGFPPPSAQPLPTPTFQQPSLPQFPGYPPQPPPSIPQGYPVAPPPAHQAQRAQTADPLAQLRGLLPENILNDHQKLIPALQLLQDLQKVGIPPDKWGPVLKAFEEQYRPPAPAYAAQGDYGRNGSGRSRSPERGGRGGRGSPVYGSYDATSRQNDEGRGGNQRGRYRQRSPMRNSPGPGAYAMNGRPMQPKYIGHDSSLPPDNIKVLSRTLFVGGANGTQQEIQDVFERYGRVQTCIANRDKRHAFVKMTTRNHALAAKVGMEEMQNRNDREVMAVARQTKWGVGFGPRECCDYQRGESIIPIHKLTEADLKWLHTAEYGGTGGRSLEGGMVLEEPDIEIGAGVSSKAMSKRVGPENNAPAKRQREDGGGGGGRRHGKKHQGGGGGGGGGGDQGYGGYSGVTGGPPAMDPYAYAARPEPVAVATPPAVPGFGFSFLPQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB70</accession>
    <name>A0A9Q8LB70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Decarboxylase orsB</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">CLAFUR5_02793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="67"/>
            <end position="315"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="320" mass="35887" checksum="DB3F453487BF5860" modified="2023-09-13" version="1">MAPALIALEEHFDSNIFTAKDNLHANLPPHLSERLQDVAELRLKEMDAGNISMQVLSHIGLMPTPVAECQQVNDKLASACAAYPDRLAGFATLLMQDPEAAAAELERSVKNHKFLGALINSHLEDGTMFDDPRFWPVFAKAVELDVPIYIHPNYPGENLESYYKGSFSQMSAVMMSTAAWGWHSSCGLGILRLFAAGLFDRCPTLKIVIGHMGEMIPYMLERTIHTARNWGTFQRNLRTVWNENVWVTTSGLFTLPPLECLLKTTPVEHVMFSLDYPFSGTETGRQFVEEIEKSGLLNQEQFEGFCHGNSERLLKIKGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBR5</accession>
    <name>A0A9Q8LBR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Concanavalin a-like lectins glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758878.1">
        <property type="nucleotide sequence ID" value="XM_047902972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBR5"/>
    <dbReference type="GeneID" id="71983702"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03824"/>
    <dbReference type="OrthoDB" id="2332199at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="29455" checksum="F8F66C0952241742" modified="2023-09-13" version="1">MGVSLSTARYLAPASFLYDFAAQQYGMLSSPNMKDVHDANLSFFSPQPFFIAAFFFPQQLFQLAWLYKLWKLDPKNAAEKKQLDHIVPFVPYYALGNVCIGTWMFFWNSSNLKVANVFVVVNTVAQLWYVFTQLQPMETRNWGSVLTHVVSKTFAGIGVLDILHNTSVAYYKNALPTLPLKIATGLSFGALGACSDWIFGGCLVYDLIALSVGQASYEQDWSRVLGGFALGTAAIVGLRNYMKPPFVTNKDYATIEQDDTDDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBU8</accession>
    <name>A0A9Q8LBU8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758890.1">
        <property type="nucleotide sequence ID" value="XM_047901593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBU8"/>
    <dbReference type="GeneID" id="71982323"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02445"/>
    <dbReference type="OrthoDB" id="3796227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="288" mass="31279" checksum="F3023780256AC19D" modified="2023-09-13" version="1">MSATTTAITTKTHVKSGPKGKGGVPSKRPLRDEDDDKGSDEDAGDGGKKKPASKVPRAYNDGIGTAASERFGLPNDIAISSIELLTYFPKHAALWPELLLRLVRNDFSLPECAVRQLYARGNLDKAEFTRRYASLRKAAKTAGQRKFNDPNFTLTSYKNGQNQQPGHPDLQPYTMADVPAGGQIEHLYHVNRMTVPAAPPPNIPLNQARATLADLANGVTQHPPPGQRGVLTKCILWAIANSQDANYDTHNLMTIVNMAGNNFVPDAGANTLTWDQDGMTDTQTIPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBW5</accession>
    <name>A0A9Q8LBW5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758934.1">
        <property type="nucleotide sequence ID" value="XM_047902103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBW5"/>
    <dbReference type="GeneID" id="71982833"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02955"/>
    <dbReference type="OrthoDB" id="3633490at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="374" mass="41409" checksum="89E95E8484013343" modified="2023-09-13" version="1">MSSSSLKRKANSPPDNPPVRKKSSVSVMAAAVAYGGSIKVAKKSRPGPALRESTSNLALAKIEQRGPLKEFGPWEKASTANRRGRTLRRRESVLTGHGMPLRPGLELAGTQLQTLKGADIASIREVILLPTSLAVIKPNWPFCFDINCTPQLGPALPDHIAEDLYQKYVCSSPLLRPGRLPYYHIGTTTIGFRLHFYLILPNAGGPPHAANTGHLTDEALQLLFDHCVCPALQAAEPKRRGFGSWMQAMNEANLKPLKSRKRSAAPEMQEERIHCFHLSSIWEAIESCDDENVQDLLQGGMLVAYGDVEGHTWHEGWKPTWAGWKKDWEAAVEKKYLIEESRISVSMELGVGMSEDGMKGGGQMSRYERNRARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC67</accession>
    <name>A0A9Q8LC67_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_02694</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758429.1">
        <property type="nucleotide sequence ID" value="XM_047901842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC67"/>
    <dbReference type="GeneID" id="71982572"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02694"/>
    <dbReference type="OMA" id="WLKQANP"/>
    <dbReference type="OrthoDB" id="9215500at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000002">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000003">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF3">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE, LIVER FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO14063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="893" mass="101527" checksum="49E866C251E9A5C5" modified="2023-09-13" version="1">MASSAGTNEDRQARQRKPSTSAPITDFQGPVGPAGISRPKHKRTVTGFAPQEIKSIEASIPEGQREAWRKYSAREFKDKDEFDAEVVRHIETTLARSLFNCDEAAAYSGTALAFRDRLVIEWNKTQQNQTSADPKRVYYLSLEFLMGRALDNAMLNTGMKDVAVDGLKDLGFRVEDIITQERDAALGNGGLGRLAACFLDSLATLNYPAWGYALRYRYGIFKQEIVDGYQVEVPDYWLDFNPWEFPRHDVTVDIQFYGNVSKYTDDKTGKQVSVWENGEIVTAVAYDAPIPGYGTKTTNNLRLWSSKASHGEFDFTKFNSGEYEASVADQQRAETISSVLYPNDSLESGKELRLKQQYFWCAASLFDIVRRFKKSKKAWSEFPNQVAIQLNDTHPTLAIPELQRILIDQEGLDWDEAWSIVQKTFGYTNHTVLPEALEKWSVPLIQHLLPRHLQIIYDINLNFLQYVERNFPTEREMLGRVSIIEESQPKMVRMAYLAVIGSHKVNGVAELHSDLIKTTIFKDFVKIYGPDKFTNVTNGITPRRWLHQANPRLSELIASKLGGHDFLRDLTQLHKIENFVDDKEFRKEFQEIKYANKVRLAKMIKEMHGITVNPSSLFDIQVKRMHEYKRQQLNIFGVILRYLELKEMSAEDRKKVQPRVSIFGGKAAPGYWMAKTVIHLINQVGAVVNNDKEIGDLLKVVFIEDYNVSKAEIIVPGSDISEHISTAGTEASGTSNMKFVLNGGLIIGTCDGANIEITREVGEDNIFLFGNLSEDVEDLRHSHMYGDFQLDPMLERVFDTIKKGTFGDAGQFSALVNSIVEHGDYYLVSDDFKSYIDTQKLIDEAYKNQEEWLTKTITSVARMGFFSSDRCIDEYAEMIWNVEPVKPAQQNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCG3</accession>
    <name>A0A9Q8LCG3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758564.1">
        <property type="nucleotide sequence ID" value="XM_047902919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCG3"/>
    <dbReference type="GeneID" id="71983649"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03771"/>
    <dbReference type="OMA" id="CEECHEP"/>
    <dbReference type="OrthoDB" id="10463734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="137" mass="15223" checksum="80233B444F41B306" modified="2023-09-13" version="1">MPGCTACNASKKRCPGGVKSCLVEKEKQEKKKQKVPREENPEKKTSEPLPKPNSPAQKHVIPANQLRAQQEAATFAAIMNAPRAELPDVNDPRIWEESSAVQAFLDFPEGEGQPGACEECHEPVSKHYFGCSRWEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LD49</accession>
    <name>A0A9Q8LD49_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="43217" checksum="A43B959EBA0619F4" modified="2023-09-13" version="1">MTCVLPTTPWHHFNDHLPWLSMGSDAGPSPDMGKSSLSQGYVSPNSDTRKSSTSSGKKRASRAGTRSVTTLSSAQLERKRANDREAQRAIRQRTKDHIDHLERSINDLRGSHEANEKIVHVTQQRNRELEEENAYLRSKLNEAGFNVNLQPTEHQRPIESTLLSIPSTSPGTTGSSIPRPGSTSTPSNHSVTAQPSASRHGSWQHQTAGFVSNAMGLPGVGAVANPPSLTTWRSHDAAQDPLSAQSASPYHDQRVEWPSNAAPYSQYVSQEQQRPQYETAPSQQTGYQPSTYHTGLTPQSEYPPNISVSSGPSAYQVQPQATFSQPTSFQITPMQVPAGGADYTSPHGQMQPPPLAATSFQSAHGEQTYGAQQETTSMQYRDEGASRSYSLGHYPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGR5</accession>
    <name>A0A9Q8LGR5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761463.1">
        <property type="nucleotide sequence ID" value="XM_047904387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGR5"/>
    <dbReference type="GeneID" id="71985117"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05239"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="62577" checksum="B54D11182DD1DF6A" modified="2023-09-13" version="1">MTWVVITRTFRSGQPFMWSNIPDPTLSVQQLQVNLTVSIYDHASFTALLHHLKPLPSMHSRVRRLRIRLDFLEQIRENEPSFGAATQYVRELNLALEHVHWVHNVVMEWTIAEHGLEDVLPESSWQRDSATDPVPEIRTSSAISPPGAGSTMQQDTRDREQIDQVHQSATHPDPHAVWTTVRPLLDDEHRFNGWRDRGNYRNPDTIQHLQVELAGAMDHPPSFWINPAWLRAIPGRFPAVRCLRLRVDFNVATVEESHRPLVVQWVYRRLYRTSGEMQWPHTVEVLLAINDGMESTFESFDIVTETSTDVVTARFQKIRSWQPLFTILPPSSTVDKQTVLSRVIPQDHQVQMTLTTQQRRPLYTGYRWQSMGNIVHISEDTVAYQAQTSALSRMTPVQKAGRTASEDEAGSVQSQANDAVQHPDAAGEDAIMQDPSADSEEPIVTRSSHAQTQGLAGPPEQTVQRHEPDDLGDDDPTGVPPLDGLNITRSQQDEQFVITELDEGDDHGQERDLSQTATNAVADRRSDDEDQSEQSMTEVEEAAGILLLLKQGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH00</accession>
    <name>A0A9Q8LH00_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761817.1">
        <property type="nucleotide sequence ID" value="XM_047905405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH00"/>
    <dbReference type="GeneID" id="71986135"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06257"/>
    <dbReference type="OrthoDB" id="3523319at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="86" mass="9207" checksum="10A91A04AC694F67" modified="2023-09-13" version="1">MAATTFNVGEQIRDHKLVTPIINGHGSPDDAVFDGGSLELLQRLCANPTVETRDQIVEENSWHDTPSDQSGEKAGKSGDLSGFLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHK0</accession>
    <name>A0A9Q8LHK0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_06337</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762132.1">
        <property type="nucleotide sequence ID" value="XM_047905485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHK0"/>
    <dbReference type="GeneID" id="71986215"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06337"/>
    <dbReference type="OrthoDB" id="1076608at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF26">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="556"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="621"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="675"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="38"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="211"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="419"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="823"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="737"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO17766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="911" mass="102182" checksum="76B46B7777EC2399" modified="2023-09-13" version="1">MIIFDSMDNAGNMAAHLVARQSNQGSNQNAQGSSVSGMVSTLIPVLLISIVIFLVFLIFRRKFDRVYQPRSYLGSLRNWQRSPKQTTGTLGWRKEFSELKDEFVLGHSTIDNYLWLRFFKMLTMMCLVGCFITWPILFPVNATGSNNDATGLDILSFSHINPGPRYFAQAIVAWLFLGWVMFMITRESKFFVRLSQRYYLSPYQRSRISTRTLLFTNVPEAARNEEHLRSQYAGVKAVWLVNVPLDLAEKVDDRDTAANKLETGEIKMIKNHYKRQLKLEKKNKTSERVNPEAGARVEVHKKDIPTHRLPKLKFLPIGKKVETIDWSRGELRRLVPEITTEQRGLVNNNKSEAQAACFIEFDTVQSAHAAWMQASNMGRKEKAKSMAKMTPKENGPEPQDVIWKNIIKPLWKTKLFSTLGTAFVWFLCIFWTIPVAVIGAISNITYLTNKVPFLSFILDIPPVVRGVVTGLLPVILLAVLMALVPIILTVIAKLFEPTQGAVQMKVQGWYFPFQVIQVFLITTFSSGAAAVVTQIINDPTTAPTLLAENLPKASNFYISYFILFGLQSAALQLLNVVPLLFVLVLGKILDTTPRKMYNRYVNLAGLGWGSLYPKFTNLGVIALSYSCISPLILGFATVGFFLLYLAFRYSALFTLGTTVSTRGQSYARAMKQLTVGIYLSEICLIGLFAIGIAESRVSIGPMIMMIIFLVLTILWQIWLGRSLKKMENESVEDNIAPSAITGDIRDSSDAEKAPGSVDETRPAGLGNNQDHLAKDGYDQAQSETADAGHEQLRQTPTGKVGLMARIKGYFNHEAGASNAIQFVSPHLSTPVRAYTQKEHDEAYLHPAIISECPVIWIARDKYGISRQEIAASKEDGYIMTDEGAEFNEKGKIEWKQDDLKQAPIREDEPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHT7</accession>
    <name>A0A9Q8LHT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-galactosidase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762001.1">
        <property type="nucleotide sequence ID" value="XM_047905333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHT7"/>
    <dbReference type="GeneID" id="71986063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06185"/>
    <dbReference type="OMA" id="QPRWTED"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-galactosidase jelly roll" evidence="3">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase jelly roll" evidence="3">
        <location>
            <begin position="118"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="28550" checksum="351C65FCFD70A4B4" modified="2023-09-13" version="1">MQGGLAAGFSAWLNRELVGYNPGNATATKVSSLLDLSTATLYNSSNVLTVVTDYTGHDQTSTGPAGVENPRGVMGATLLNANSTATFTQWKIQGNAGGSSNIDPVRGPLNEDGLCGTRLGWHLPGFDTSGAAWSDGSLLTGLNKSGINWYVSTFDLNLDENLDVPLGIELGAPEGTVASVQLYMNGYQYGKYIPQIGPQTRFPIPPGVINNRGTNTLAVALWAQTDAGAKLSNAELFAYGQYQTGFNFNQDWSELQPRWTEDRLQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LI73</accession>
    <name>A0A9Q8LI73_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_06592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762243.1">
        <property type="nucleotide sequence ID" value="XM_047905740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LI73"/>
    <dbReference type="GeneID" id="71986470"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06592"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14670)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="66"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="511" mass="56624" checksum="994DAA8872726550" modified="2023-09-13" version="1">MDADSKHSKQSTELHEIRKSLDNAKTVALKDGNHEQAAFFETFATKDAEWVSYQNKKLLRKVDMHLLPMLILMYLFNFLDRSNLAQAREGTLEADLGMKGTDFNLATSIFFIGYLLMQLPSNMLIIRVRPSLYLAGVTTLWGVVSTCNAATHNFTGLVVVRFFLGFVEAPFFPGVIFLMSSWYTRAELTRRVAWFYSGSSLANMFGGLLAAGILGNLHDAMGLSGWRWLFIIEGTITIFFGLCAGFLLPDYPSTTRWLTQEERAFAAWRLYSDINESDDTHSAGVWDGIKLALQDYRLYLFTLLQHMSLLSQTFQYFFPSIVQTLGYGNIATLLLTVPVWFATFLTSIIVTLTASKTQDRSLHIAILMLLAAIGNAIVTATTSVGARFFAMFLMPMGAVSAFVVIVPWIANSFPRPLVKRSACVAIANMIGNTASAYGSYMYPSSAAPQYVPGGSANAVICLGVAALALSLRWVHKRGNRRLEVVEEVVEYSRGSGGEGGEGRRVGLRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ65</accession>
    <name>A0A9Q8LJ65_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_06578</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762729.1">
        <property type="nucleotide sequence ID" value="XM_047905726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LJ65"/>
    <dbReference type="GeneID" id="71986456"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06578"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031852">
        <property type="entry name" value="Vik1/Cik1_MT-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16796">
        <property type="entry name" value="Microtub_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="469"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="220"/>
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</entry>
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        </source>
    </evidence>
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        </source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="960" mass="104168" checksum="05729D92993356D2" modified="2023-09-13" version="1">MPSAQMHPLHTGWTEKPLPQPPSPTLTNPDHILPSSGFPLVSSPPRLTRRPPSPSYLRDTDGDPATAKAPAMAKGKKEKLGLMSRKMMLLRSCTASGGHVNGNGNGNGTPRSQRSLDFDFIPSSPVLQDVGNLAPEQPEYLQPPELDRRSSSPGSSSSGVSGLTGFLARYAKPDGTSDDEVLYEGEGSPAVVRCDSSVDHDTDRDTERRRQQLEEYNSAILSKRAEQILANAKKRLNVMEGNLRGARDLVAPLTAANLKRATSLGSAHYVPVYGQRYASNGHEDGGQALPSPRRLHLQTSSPMIGRDYQSHTRGFSETELPERPYTSLDGPQYIGPRVVRMPPHGQTATPLRGSRSYDSLGGSSGIGFGTGRDRPLHHAIESPDSNHLEPLPEADEGRRSNRNSRNDAEATANNGLGLYRPSSRTSDLREQMSSLKGKISTLKERAREDSLRRQTQAHLRDSSPLNNASAAAPEFFYSPSNSYGSPTLDDNAGLGWTSNSNSPASPQGPHMWEDGMPVAGSRNAFAEHATSQQQHGTQQARVVKIVAAKTPDSKFQVKVAKASQSQPQSVHRRTPSGTAIVDSAKNRYSHHQQKNSEDLPASHESEDEDYLGIPSPDSIIEQYDSFRNESMADTDIDDDDAPSEDEGSVYEDAQYEQKPVVAHEDREDAFDYEHFFLHSALGTYSNGRRGSASSEASMSSVETARGLTLVSGDSEDLFHHESALYPPPTPKTPERLKEIERNLHRRTVSDESVSTLATYATADEDPADEDPVSPIDERHHQLGSLDHRPISPMESDTSSRSRSSARTSIPAKGHSSARPSSRPGTAVRRAIRSDSGSERADSGVGILHHPAGSLDGQRPLPRSATPKLSNSRPPISAISSPSSPHGAARQDPVSVAVNALLDAEGNPLGLRNKAVVFGVVESLRRTIHMLQQEDEAGHENRILRRRLDEAKAALDGRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3F4</accession>
    <name>A0A9Q8P3F4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756336.1">
        <property type="nucleotide sequence ID" value="XM_047901008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3F4"/>
    <dbReference type="GeneID" id="71981738"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01860"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="479" mass="53187" checksum="53F274B3B30F35D8" modified="2023-09-13" version="1">MAPTRAEKGKGATGGAGARGGEGEGGGGGTGRLGRAATGKKRKADETETGSEPTPKKPRRPRRKLQNSAATVTNSDDEDDMVQPAATASKSKKRKDAPKNSNADANESTRKKARKTADTTAATPNDDLQQQEQEEQSAGKKSKQPPQDIRRHNVEWQGYRPGEIEYRTADGPRYVGWLVEYVDQRNASKIFYNGADFLEGGPFAFLHPRYLAPITLAGFRAGNHVFDNVHQAFLYCNAIMQAVAPEKHSTLCEVNGDAVSSKSLPGILMSLTVVRKKEDVNAAHKVTKATYEDVANSFRELSIQDPTWAKQVQVMWADDIKRACLKHLTRLKYDQNPVLRLALMMMGKCPLFFAAKDKGRGVGMMAHQVPLRKSKTRPFDGQNLEGIITQEVREDIRRDDEAKAGKVVWPDKPCLQFFRLGERRHQAKQATKLEPKAEADIASAQLKHRDEWIASSEHTKGWLNYLMLAERKRKADLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P435</accession>
    <name>A0A9Q8P435_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bromodomain associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_01929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756934.1">
        <property type="nucleotide sequence ID" value="XM_047901077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P435"/>
    <dbReference type="GeneID" id="71981807"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01929"/>
    <dbReference type="OMA" id="EWEEDWQ"/>
    <dbReference type="OrthoDB" id="5402929at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00076">
        <property type="entry name" value="HFD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromodomain associated" evidence="6">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="29175" checksum="F515719355D86B72" modified="2023-09-13" version="1">MSQAHDIHRALLRPTIIHTLRAAGFHSTKPSVLDTLVNLAERHLMALATATAQHALSSHNDPVPTITDVRMALSDCGVLIPLDDPAEQAWKERLRIPLTELAAPENGGRTRVVAEKRKREDEDTRDIRDFTRFYDSTQFREIKRVAAPEVTSAMLPAVGVGGGVVRSEDFLTILKKKHSKTGDDPRLQGTVLGRSADSKDLVVEGGSVQHIRDWRPRNKVEERPANMQPPTVTARDASRATEIEDDSATRSTEEGKATQEVTSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P521</accession>
    <name>A0A9Q8P521_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P521"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="23178" checksum="5CE4D15C1A870A3B" modified="2023-09-13" version="1">MAKKKKRAKAKKYDEVESVKPPKPLKNVEPAKSTKSFRLPDLPPELWSKIGKMAVLDAPCCWTETIGCVAQPPRRARTKAIRSSNIPVPAARQRPPITRVCKVLREELLAFHYSNHMRLFIYDTGTQFGTIGKWLRAIGAENRRALGEVTICIWWGMPLHPLVHDGGGTAFEKWMKKHWRIDLRAKSCQILKSIIGDIVKFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5T7</accession>
    <name>A0A9Q8P5T7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit ASK1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_02613</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex ASK1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758660.1">
        <property type="nucleotide sequence ID" value="XM_047901761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5T7"/>
    <dbReference type="GeneID" id="71982491"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02613"/>
    <dbReference type="OMA" id="TIQFHIP"/>
    <dbReference type="OrthoDB" id="5573898at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="466" mass="50815" checksum="27490D3AEBF97889" modified="2023-09-13" version="1">MKLNIACLGALYLQRATTSPKSLALDKAGGLSTALDSTSTGASSNDSATILARSDRSGDVEMGGIDDRDYMIQGTPPRNPSPIRDPILAELTETDAQALIQKGAKLYAWMSEPNVGTLTQLLRQDNKLGPEACLQSDFTTYPQDLVDAGWDRDPLGIDAPLSDFQESIPLKLMVDGLGISTTWEIPPDQQGDNEYVTWHHTDPNFDGTDHGVATGAFYSIVYNTKDGVIMLVSNYGPRKELPSQVSGEYQNRGQAFMDKFIADYQYPALSHVSDVSALEYNGQCKRRNHNAKDLNKLIMVSSQSDVSVQVVDYLLKKKGIQHLAPAREYGRYKAPAWPQKIRYLPGSDGFKLLLANPNGNLATFLLIQHRQEFGLKRVGKIDVFDDDHYDHSPQQGYKGASMAYYLEDLDSKGKPVVKAGASGSGAGKKPLKTGGSGGRTGKSGKIEKPKRPGLRSGGKVQRMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9A8</accession>
    <name>A0A9Q8P9A8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762440.1">
        <property type="nucleotide sequence ID" value="XM_047904947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9A8"/>
    <dbReference type="GeneID" id="71985677"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05799"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="257"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO18074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="679" mass="75908" checksum="062EB5616BB876FE" modified="2023-09-13" version="1">MMCHVYDIAVCCVYIQRGVSDSLEHTGRFNGWLSRAYRDSVLFGREPLCSVLGISRRFLLRPKSSTPTLIAKMSTIEPLYSTLRFVSSSGPPSSGKRRIAQHACDRCRQRKKRCFNGDNAVTDDAGDAGRVSSTEPGDADATKNTNHHILDVASGMIDVSNGNAASNSHPRYIGDLNPEVELLAATEPNQVPKNSTGVWHSESVQNSHESGDKHVAAPWSILHGLPLGTQESLLPLLRQQCLETIPTRENFLELERYYFERIHSLLPSIDEAIYRSSLVGSPTENLQKQCVCLLASTSLSMRQYLRLGNDLRTLQPNEYARRVVGAMRLIIDLALVTDKIVLIYALTTMSLFVYGRESLELTSQYFFRAVQVAYSIGLHQPRDTKQDEKVAGMFSYIWSIDRLHAAMQGRPIVMHEIDMAKSPLSCAVDQQAGFKVLVHIAALLDKVIGLYRPTALRKEIPDEEFPLFEEVLEKCNALTLRACDQASLELFYHAVAVLSCRYSSGPAMERSHIRNARQTSSTTQILAILDKLDPTNTAMLPFVPYAVSLAMSTAYHDFRHGKASTRRERAWKNFVKSHRHLAPLGIISWSAAFMSDLASKLLQEAQSRRETRPSSPVTESQPNHPTMAADQNASLNVAEFSMDEFMTDINLDLDGLFEGALDPSMPWQFQDTSYSGSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9V7</accession>
    <name>A0A9Q8P9V7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762847.1">
        <property type="nucleotide sequence ID" value="XM_047906312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9V7"/>
    <dbReference type="GeneID" id="71987042"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07164"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18321" checksum="C24F6F36326973E8" modified="2023-09-13" version="1">MSDNAAPDANALAAPVPSAGPGLSEELLETCLKTKRPVYRAIEDLLPDYLRWGHGEIQREWRQQYNEDCHPEIVYDILVRAVRAARRHARIAGPETVVTTIQSRSYVPFRMAWDNAAMAFAMGFGTCEKSDDEDEEEAEMDAVGGRMAFMARKYPEALAAMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB28</accession>
    <name>A0A9Q8PB28_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763570.1">
        <property type="nucleotide sequence ID" value="XM_047906374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB28"/>
    <dbReference type="GeneID" id="71987104"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07226"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000003">
        <property type="entry name" value="Insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000005">
        <property type="entry name" value="nardilysin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000004">
        <property type="entry name" value="Putative insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="7">
        <location>
            <begin position="42"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="8">
        <location>
            <begin position="230"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="9">
        <location>
            <begin position="414"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="10">
        <location>
            <begin position="809"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1119" mass="126935" checksum="878D9CB5A0673229" modified="2023-09-13" version="1">MADRLYSRPEGNTQRLADELEKPLLDDRTYRVIELPNKLQALLIHDPDTDKAAAAMDVNVGSLSDPEDMQGVAHAVEHALFMGTRKYPGENDYNSYLTKYGGNSNAFTASTSTNYYFELSASSKSNSPTSSANTSQASLLSNVSKHEAPLYGGLDRFAQFFIEPLFDENTLDRELRAVDSENKKNLQSDNWRLMQLNKSLSSPHHPYHLFATGNWDLLHDQPKARGVVIRDEFMKFYSTQYSANRMKLAVLGQEDLDTLQAWVEEFFTAVPNQDLPKLEWTMPALTEKELLTQIFVKPVMDTRLLDISFPYPDEEEEYESQPGRYISHLIGHEGPGSILALLKEKGWANDLSAGAQPLCPGTAFFTIMLRLTTDGQTHYQEVIKTVFQYIAMIKESPPLEWIHEESAKLAEVQFRFMQKIPASRTVSRISGVMQKPLPRDKLLSGDALLTKFDPAGIKKGLDALRPDSFRFTLVSQDFPTDFPSREHWYGTEYKMEKIPADFMREIQQAYDSSSTQRPAELHLPHKNEFIPERLDVEKKKVATPALTPKLVRNENNIRIWHKKDDQFWVPKGNVYIYLRSPLINSSAFVVECARIYKELVDDSLSSYAYDAELAGLEYGISLHGDAFEISVSGYNDKMHVLLQKVLESMRDLEIKEDRFKIVLDRLERGHRNSEYMEPFRQVSNYRNWVNKPRAYLPSELLAVLSSIEVDDVKRMHPQFLRQMHIEIMAHGNFYKEDALKLGDLVEKTLKCLPLPRSQWPEDRSIIFPPGSDYTYKHTLANKENVNHCIDFSVHIGDAQDRRLRAKLLLLSQMLEEPVFDTLRTKEQLGYVVGGSPIVTGGRLQYRVLVQSEKPCPYLEERIEHLLSTFDQTIKDMPEKEFEAHRIGVINKRLEKLKNLNSESGRLWYHITSDVFDFELVNHDVEALEKLSQSEIVDFFNLYFNPSSPERAKLSVYNIAQASSDDIAANTSVSEQRANLGNAVSSMLTQLQLPAEPEQLATYFEKIDLAKPGHVESIVAAVGEYLQKVAGMAAEDAKVIISQAQAFLPGLLPSLGIKAPAPQTNGDANGHANGNGHVVEKKKESILIEDIKAFRASMPLTAAGVPVKDISEFEDLEPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM5</accession>
    <name>A0A9Q8PBM5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763895.1">
        <property type="nucleotide sequence ID" value="XM_047905806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBM5"/>
    <dbReference type="GeneID" id="71986536"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06658"/>
    <dbReference type="OrthoDB" id="5280838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38119">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="856" mass="95621" checksum="A82CED383487927A" modified="2023-09-13" version="1">MGSLRVTLKTGKADSVSSASSASSRRSRGTACAECRSKRQRCTHATEEIIELSDDEDSSEEPTPRRRVKRVVDSDYEEEDEDEDIDEDEDEGEDEDEGEMMRTKAPLRRDRWALSPLQQKPSNLPNDPLEATVDEVGAWDAKHLIASSNRNALLVQSLLWAGADIRQLIQQYLDGAKQKTNFRQKLEDALTMVQVGQRPAGADEETKIMLRCARLYLSYRLLDLRPCAGKTMEIPWHDVRDRVDLFVLMLGNIVEKNDGKLFTASRASQLKEHPSAEHRSSRIDVNMHDAASDANTCALAHENAPLQQQSEAHSEQTQLDTMNEPQHATTSEDTTNITPPTPPPMSAHTKPTTRETNIATIMAVAKCSEDEAKRYLEDANGDLQQAMLKSLTPAPVVAAAEEPRLPTLIDDALEAYAATLQVCTAFPEATFWCYLGGDLRACRVFSDDLIDTSPAFAQLLELPSNDSPSRHGVRHLLMLTIDPAESLPILARHDLDAPRAEPKPATAQIATPDGVQIDTKAKVENGEATPMPDAPRIDWAGAYESMFRMIANFPAKHLGIAQENVDAARPKIEMVAQVAERYSAVSPESSVTRELERLFSGFINTHRLWQAIAKDAARWLVLSVRLQSPLLYNEAFVHVAGAYPAWPWAFNEEKVRTNLPDMYQAIVVRSKELEFGRQMAERMLLFTTLTGTPKSGPNRGKPVPVNQRVRPITYSVVNIWRDWITGHLSHIDSGCTTKPDYQDPICKHEGECLTVAGFHRTIGRGGDSYLPPESLIDEYWDVDQFPDLDDSILRTTLKELKRAAAKIVAPLLQSRLQYDGKDKLPYLTCIRVREEDVPWQKGVKKEVDGDGDEEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBX5</accession>
    <name>A0A9Q8PBX5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763999.1">
        <property type="nucleotide sequence ID" value="XM_047909280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBX5"/>
    <dbReference type="GeneID" id="71990010"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10132"/>
    <dbReference type="OMA" id="SMVRTHH"/>
    <dbReference type="OrthoDB" id="1290869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="211"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="303"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="703" mass="79292" checksum="CECDBEAA8EBAFBBC" modified="2023-09-13" version="1">MRVAASLGRACTGFSSRPVRPQVLRHIQCSIRSGRPTKSFSILRTARNTFRAPPAPVKGGSLLLAALSPAAFIHIAEDDDNGGGLTHEEHMLQLSRQELAEQVPDRLEYSTKFRRSIWRFVDTWIVEPLATALRFLHLVIIFVPVIATMPVICFGGRQHDRDDQRSGTLWWYGFLVSSMERAGPAFIKLGQWAASRTDVFPKAMCSVMGALHSNAPAHSLKVTKETIERSFGMRFELIFEEFSEKPLGVGAIAQVYKAKLKPDLAVSNPDQYDAGEEHPTLRERALKSVDPLLKSTPQRIPSTYVAIKVLHPKIERIVRRDLKIMGFFANIINAIPTMEWLSFPDEVQQFGEMMRLQLDLRIEAANLTLFRKNFRNRPTAWFPYPYTQYTSRQVLVEEFATGIPLEHFLENGGGIFQKEIADEGLDAFLHMLLLDNFIHADLHPGNIMVRFYKPVPLRGEAKFSAFKRIIKNTPKDDVEGSEDVTEDVLARLRPHRHDKSSWLETLQKIDEENYTPQLIFIDTGLVTELNETNRANFLALFKAVAEFDGYKAGHLMVERCRQPDAVIDKEVFALRMQHLVLGVKSKTFALGNIKIGDILNEVLDMVRGHHVRLEGDFINVVLSILLLEGIGRTLDPSMDLFSGALPILRQLGAQNAKGGLKSLQSGDLSMIKVWAGLEARKFLQASIESVEMCVKYDQLSPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD73</accession>
    <name>A0A9Q8PD73_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N amino acid transport system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09877</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764646.1">
        <property type="nucleotide sequence ID" value="XM_047909025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD73"/>
    <dbReference type="GeneID" id="71989755"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09877"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF479">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="58"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="468" mass="50555" checksum="CC7362A2CD57768B" modified="2023-09-13" version="1">MLGSSRSDVHPLRTMSKSEDYTYNAYDASGQDSPRGNGDYDSRDVFGHEEHHDIKYKTLSWQIVSVLMIAEIVSNGMLSLPSSLAVVGMAPGLVLIIFLGIFAAYTSVLLVRFKLRHPEVHNMGDAGKIMFGVVGREVFSFGTIAFAFLLAGGQMLSGQIALSNLSSNGLCNVSFTGIFAAATFLCALPRTFDGLGWISIPSVLSITIAGIVGMVGAGTHPVEGRSVVAARSSDFYTAFFSITNPVFAYCGHFMFFALMSEMKRPQDAVKAAYTLQGFATTYYAIFAGVTYGFIGSAVLSPSFSSLETAWAKAAYGIALPNLLIAGALYVHTASKIIFVRFFRHSRHLHDHTVLGWVVWVSLVAIFSAIAFVFAVGVPIFNYLIGITASLFAAWFTYGIAGMFWLHDAYHDGEGIRSWRKRWGGTLMAVLTIVVGLFICVAGLYVTIRAIVDAYANGTITAPFSCGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDK5</accession>
    <name>A0A9Q8PDK5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764828.1">
        <property type="nucleotide sequence ID" value="XM_047909662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDK5"/>
    <dbReference type="GeneID" id="71990392"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10514"/>
    <dbReference type="OMA" id="PKWYDRI"/>
    <dbReference type="OrthoDB" id="1725934at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098826">
        <property type="term" value="C:endoplasmic reticulum tubular network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071788">
        <property type="term" value="P:endoplasmic reticulum tubular network maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903373">
        <property type="term" value="P:positive regulation of endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="4">
        <location>
            <begin position="248"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="381" mass="41810" checksum="BFBFE7D0BE3BD22E" modified="2023-09-13" version="1">MVSFWPFKSDDKSAASFEKELKQLSTKITKAQARHDSFRSNQRRFKALWTLYTTFLYLVVAAVLTLVTGWDKWSYAEYTAVAGSPVLIFGVRTGLDAYYNYRVSSTQRYLDDLNKQRDQAISRLKSATKYDSTQQLLEKYGGSPSGKRQPSPQPQGKRKSDIGPGSQVSPQNRTGFAPPPTANIPGRQPPPTANIPRPEGAPPILPRPSTTNEQSGPNEEFAPNAFSAPSRPPTIRQPSAQYAEGPKWYDRIMDVVLGEDETQAKNRIALICQNCRLVNGQAPPGARTAEDIGKWRCSACHTMNGIESEHKQVLRAAGLESAPTSPVPQSAARAHNDAQAADNHEEDEDEESDGQDEPTSAGADTPPAGSTRSKARQRKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDS0</accession>
    <name>A0A9Q8PDS0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764936.1">
        <property type="nucleotide sequence ID" value="XM_047910500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDS0"/>
    <dbReference type="GeneID" id="71991230"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11352"/>
    <dbReference type="OrthoDB" id="3643063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="127" mass="14363" checksum="240B3AA2F6C45082" modified="2023-09-13" version="1">MGKRKQMDDGVPSREDKRAKRQTSAATTSTPSRVLRSVKAQTTAAARDAVFKTTELLENILIQLPPMNIIQVQRVSKLFKEVIENSPTAHKLLSPEVKSESKHWAVKFDFTRQRWFYGQSGTSKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDV5</accession>
    <name>A0A9Q8PDV5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxylase/desaturase CTB9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765125.1">
        <property type="nucleotide sequence ID" value="XM_047910777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDV5"/>
    <dbReference type="GeneID" id="71991507"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11629"/>
    <dbReference type="OMA" id="DTHGFQW"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="34241" checksum="4D74078A29F2E86A" modified="2023-09-13" version="1">MPHSTDPPPGVIKAEVNYFLEPPAGEPYPIIYPGLVGSRRRKWDVRSVEVNDLRGRENEFEVDTNGFQVVAFATKEKEYDDDDRIKQEVYPEAEELIKKTTGATRVHIVNHICRRYSTQTAMDTIKDLPDDAEITLQHPAMAAHVDQSYTGAQWLLDFQTEQGNITHKPNTRWGIINIWHPLKPVKREPLAVCDARSVADSDLKPVKIRMKRPKDGVMSEYDTELWYPVYKPEHKWYWPKGLTQDEALLIKCFDSKQDGRARRAPHTAIQTPEDEGPARESIEIRCMVFWEDEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEM3</accession>
    <name>A0A9Q8PEM3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765545.1">
        <property type="nucleotide sequence ID" value="XM_047910242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEM3"/>
    <dbReference type="GeneID" id="71990972"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11094"/>
    <dbReference type="OMA" id="FFKHMPT"/>
    <dbReference type="OrthoDB" id="5397682at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604:SF3">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="727" mass="81653" checksum="5290ABF17C0EB713" modified="2023-09-13" version="1">MSLERGIPARARLLTKDEELGKRDDDFTPARSRSACISTILPWRWRKRRLFAGIALIAVIYLFIQNLPTDLAEINRQAGLQSGRYTPDGTRDTRYTAAYDPYKSVAHEEPSGPPPRDKSIEDASDKHYYNGIVRYYKLAVSLHKISRTMGSLAQNRNILFAASSTKSLANLVPMACEMARADRSHAHVALFGRSTIPMDDILSINGIDEEDCPVYWHDARSDYAEYSSDARVEASVKGAMKHIQDFMHPQAIIVDSARQEDAYFSRAIKTAAKNIGKALIEIPSGRYEQFMWLTRLDAASLSAWHIPSIEILIHAPNDRSGRLIRLLQSLYNADYNGLHIPRLTIELPSKVEHFLGNYLAGFNWPPGRTFEESSQLTLRHRIPSSRTSSEQASIRFVESFYPSNGQQSHVLVLSPQAEVSPLYLQYLHYLILEYHHTAWGSPGSEDLLGFSLDVPSLFLDGKPGFVPPTIANMTYSKYDDTVDSDAPSPFLYQAASSTASLIIGDKWLEFHDFLAKRTPASHSQKTGKKTRKLASEAEPAWIEYLLELMRARGWTMLHPAASFVTIHNELAQVPEEYARPPADDKEATEAFKKSELPEEEPYVLNAEPPVPAEHVEADPTRHLQPLHQMLPFNGELQDVTQLPCVGHGGELITFEELAERTQKYKPEFRASIGGCKAAEASRQRVAPMKRTDDLFCLPGLDVRYLDDEEDVAAHVAEAIADMTDTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEN4</accession>
    <name>A0A9Q8PEN4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765412.1">
        <property type="nucleotide sequence ID" value="XM_047910468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEN4"/>
    <dbReference type="GeneID" id="71991198"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11320"/>
    <dbReference type="OMA" id="QIHAYHS"/>
    <dbReference type="OrthoDB" id="244190at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15859">
        <property type="entry name" value="SNARE_SYN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000060">
        <property type="entry name" value="SNARE complex subunit (Syn8)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF423">
        <property type="entry name" value="SYNTAXIN-8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="172"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="262" mass="29503" checksum="33ABCA1B2E4B46CB" modified="2023-09-13" version="1">MSATTPNQLFLLADHLKLSLLERQRAISLNLQPTKQDASITPSLTQLQAGIDRLAAQQDDLGTANHSTSELSRIRKQYAELYAQFHGTTPPSVSTTHPNDPAPEQDFAHARSHPTKSPRNKTVRFRDNPNDEDDDDSANRAALCQDQQRYRDEPEAPDQSNLDNVQIHAYHTQVLREQDEQLETLGQSIGRQRVLGEQMGMEIDDQNALLDDVERGVDRHSNTLGGAQKRLGHISRKAKDNWNWITITTLIVILLLLIIVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEX7</accession>
    <name>A0A9Q8PEX7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxybenzoate 4-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11651</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765612.1">
        <property type="nucleotide sequence ID" value="XM_047910799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEX7"/>
    <dbReference type="GeneID" id="71991529"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11651"/>
    <dbReference type="OMA" id="CLEVIRC"/>
    <dbReference type="OrthoDB" id="10016252at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="22726" checksum="342C491D6CBA4E77" modified="2023-09-13" version="1">MIGQPDIEHALLKRLPADTVHYDERVVSISEGQESVTITTDQQRTISAKYAIGADGAKSMVRNALGISFTGTKPEMVWAVLDTFIDTDFPVCSEIITFQLNEQSRVSWIPRERGMARFYVLLEGEVTQEKAEASIREHMRPHWVEYKSTEWFSTFEIKERIASSFISKTGTRRILLASNAAYVYAINGGQGLNTGIANTFALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF75</accession>
    <name>A0A9Q8PF75_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765726.1">
        <property type="nucleotide sequence ID" value="XM_047910224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF75"/>
    <dbReference type="GeneID" id="71990954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11076"/>
    <dbReference type="OrthoDB" id="5314997at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF8">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="419" mass="46554" checksum="01A8AD72AC49B421" modified="2023-09-13" version="1">MGNIATTITKGTTDEMAPTLKRTRDNRDDLAQPPTKKPRLEEGGDNNATASAPRDPQRTGKDPVRIPHPLPPRPPQASKTAGGAKASTTTKAREEPEHESKTGPAATSDKKMRPEQPAIITATPSTAAPTFAPSDETGRDSSESTARAPAASPSPPQPRRKTGFLDLSAELRNKIYHQNMSYPDEPSTRTDKNTPTEPTILSVCKQIRAEASKMYWDKPFVFNDMGLAADFLKSITPEKRALIKDIQVVAPSPDRVAELTLRRVRRALIAWNKAYARKGLKDGVARIQMQIHEYMKDENGVDMTDHDGNRMIGDKKVIWCSARPLDLRSDDQKAKDKKAADEKAAQELAEKEEAKKKMTPQAQFDKADKEKGAAEQKKSKFDPARAEDIELFKTVRTHRNVFVNVRKTAKDLKKDEEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFM9</accession>
    <name>A0A9Q8PFM9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765951.1">
        <property type="nucleotide sequence ID" value="XM_047908135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFM9"/>
    <dbReference type="GeneID" id="71988865"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08987"/>
    <dbReference type="OrthoDB" id="9977941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26146" checksum="C76E82A77051BFDA" modified="2023-09-13" version="1">MSTATVKTRTIYHFLEPTFIENIVIRPNGHLLLTTFREGSVYNLDPNAASPEPELVAKLPGTTALTGIVQIEYDTYAVTGGIKAGSMKFEKSTMKVFDRLLGLSELASKGPLGANGAKVRDGYFYFTNSAQELFCKVKVDSQGDTTGDIEIVTHNEEAKHNMPYDDFDFDSEGNAWITVHSESIYRIDPGGRQTLFIGGDGSPLQGPTSLAVSKDDTKLYVACAGNMGKWRGSVVEVHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFR4</accession>
    <name>A0A9Q8PFR4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GMC oxidoreductase family protein Mala s</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_08943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766024.1">
        <property type="nucleotide sequence ID" value="XM_047908091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFR4"/>
    <dbReference type="GeneID" id="71988821"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08943"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="401" mass="44216" checksum="9B786832657F8F4F" modified="2023-09-13" version="1">MSLSIAFLGGTDGLAVANKLSVDESVSVLVVDAGVNESPGGEDRGDSPDRWSYTSTPQENANGNTQELPAGKLVGGTSQINGNVYSRPESSQIDIWGDVNNADWSWNTLLEYYKSSETLSHPSSDQEEGGYTVNEDYHGLNGHDNVSFPAETNADFHKILEKTANNFSMPLNRDFNGGNARGFATYPAQFVIEGEREQVRWSAREAYYLPAQKRKNLELIDQPTCIRLAWKDPSGGDNKAITADGVEIASTEKEQTIKARKEVILSAGAYRSAPILEFSGVGDKKLLSNYSIDSIIDLPGVGENLQDQVQGTFFFNRSEKSSITFPDPVGDEITTNFLFHLTYEDVLQDGSPEFQDRVNGSLSDYADSIEKHINSTLSAVQIRKSLQNPTRQHLQHPRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFR5</accession>
    <name>A0A9Q8PFR5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31878" checksum="CE55993EB20ADCC3" modified="2023-09-13" version="1">MRNYNKRKTARPSIPKSSDENASVPASVAVFGTYELLEKIIAHLPLRKLFQIQRLSHAWQDLLADSIQLRKKMFLQANGVPFRDTCNSSRNLHLKFNPTAVVEVYTGDRTGVSHVGIHNRSCPTGKYYSRSNLYATMIERCDRNDLIQVTIPSRTIDYTLLHPCQALGSWRKMLLTQPPITALDVKCYQGVSRYSITAERVYATVYNPAGLTYGDVVDLIITLRQQGAQVVSEDRWTVKDFSGSFDSTMFDGDKMLGLRMKACTGKMDEDGNGCCGCLQLFVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGU8</accession>
    <name>A0A9Q8PGU8_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_09645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71989523"/>
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    <dbReference type="OMA" id="CTRSNAR"/>
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        <property type="component" value="Chromosome 9"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="177" mass="19640" checksum="1E4D406E16CD2A12" modified="2023-09-13" version="1">MSLSIPVNETMATIHDATSRPFPTFAVIVYQVVMWLIFTYNWVVIGAAWVIGLSLTSALGGGAFLLVRWLLGFQDEWRKDSTTKHEGPREKFMIATVGTLIFQIGLLMYLAITLNYNRWMIFGASFVAVPMLWGAVLTIACMGVAMSKACRDMRSKDRSDSAGKEVKAGRDAVTEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIB2</accession>
    <name>A0A9Q8PIB2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carnosine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767291.1">
        <property type="nucleotide sequence ID" value="XM_047911402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIB2"/>
    <dbReference type="GeneID" id="71992132"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12254"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF13">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040154990" evidence="1">
        <location>
            <begin position="17"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="48585" checksum="FD220CB5D2854ACB" modified="2023-09-13" version="1">MLALLLLCWFAGVVTSAVDTCLAVQREPKLPQCQALSSRHHAEHQRLLHSISRSHGRWNNKHPRWAILEALHGYDRYREIAGAEIDRFEDLYKHVPKKHKKILESTIQYQNNFQEARTLLDHNAKTCQAIVENGLALYNITRAELNTFITESDNVEKKHRDNKHRVLRTHTSHALKHVVRDWSRDSHAERQATFPYILDCLSHHLDLTQPTNILIPGAGLGRLAHEISHLSPTVTTTSNEKDAYMNLAYHYLTSPTHSSPSSLNFSLHPYLESWSHARSRASLYRSVQIPDSHLSLNAPNLLVEGDFTTAFSYQPATYDAVVTLFFIDTARNLVQYFETIAELLKPGGLWVNVGPLLYGSAPFVQLSLDEVLLVAREMGLEVEYRAEREVMYDFGAGNMHRNGYVAQYWVARKVSGEAEKGKGWWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIF2</accession>
    <name>A0A9Q8PIF2_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767419.1">
        <property type="nucleotide sequence ID" value="XM_047911456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIF2"/>
    <dbReference type="GeneID" id="71992186"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12308"/>
    <dbReference type="OMA" id="THFACER"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF242">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="72"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="277" mass="31666" checksum="7E0AF02CB318BDB3" modified="2023-09-13" version="1">MAPRQDPASKTQERELSDPDSLRLKSIFAFASAILLRPEPFETIVPKWELRYTQPFVCKGAPYIVRTISCDPLIQHLENFISPAERKWLLSKSKNLSQPSEVRRKIGEWITSPHKTSTTAYFPKDDPVARCISERAAQFQGYESIDDVDRLQVTSYVSTQEVKAHYDWYGALEKVEPHDCKTTFFGILDADCEDCGTNFPKIKMTWARQDRKWCRLVDCDSSSLTVLPTPGSAVFWRNLHTNGSGYVRTLHAGMPWSRGEKVGLNIWTKQRFDVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIP3</accession>
    <name>A0A9Q8PIP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase-like protein TwmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIP3"/>
    <dbReference type="GeneID" id="71992192"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12314"/>
    <dbReference type="OMA" id="CDMFITP"/>
    <dbReference type="OrthoDB" id="2532955at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052389">
        <property type="entry name" value="Sec_Metab_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110">
        <property type="entry name" value="CHROMOSOME 23, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110:SF1">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="1">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="2">
        <location>
            <begin position="155"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="319" mass="36347" checksum="543FB371671EE001" modified="2023-09-13" version="1">MGASETATAVYQTSSHTYNAKFRQDWCIGSVPHGGYVTATLLRVVKKHFETTLAKQDQPHTIALHLDFLRRTQTGPATFNVKDVKLGRQTSIVHVALSQGDREEVVGYVTQSNLQKETGLSFITNFQAHPQRVPLSSTLAALESGADPLWTEKKAWPNETFRQATKQIRAWFPRDGQPAQNIYDEWMCFRDPSEKWTNENLGFIVDMFPQICESFYFNGFDQYNPKLEEYFSKEELQRLTKGKAPFWYPTLLLNLEVKKDLGEGVKFLFSRLQTKSIKNGRYDLEVLICDEGGELVALSHHVCFAVSAERNLAARRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJ12</accession>
    <name>A0A9Q8PJ12_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal homeostatis protein BSD2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_12800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767683.1">
        <property type="nucleotide sequence ID" value="XM_047911948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJ12"/>
    <dbReference type="GeneID" id="71992678"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12800"/>
    <dbReference type="OMA" id="SFVWNGM"/>
    <dbReference type="OrthoDB" id="10003116at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="346" mass="36780" checksum="76C2F80771F15A7D" modified="2023-09-13" version="1">MSSQRYQPVAAADDDDDHVSGPSPVAAPDSPPPSFRSQQSSRRPSREHQHQTSDERDLDDAFDAPSDDEDDDDTRDRRRLMGGSDATSPAGSQGSNQLRPGAPARALTPIPTFTPGAPSGRVIGNSSDGVFANIAAKPRAGDDVDEKPPTYEQAAADATPPYWETTVLSPYATTGNPDDVFIDGLLVGSLFSFIWNALISMSFQLIGFLLTYLLHTTHAAKHGSRAGLGITLVQYGFQMRYAASVGHPSDDPTNGAPVEAVPDDPNSHDFDPSKVAGADGAAAAAASLSTTDWLSYALMIVGWFILIRAATDFMKARRQEALVRSSPDRGLGVAVVAENERPETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJA1</accession>
    <name>A0A9Q8PJA1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase [NADPH]</fullName>
            <ecNumber evidence="6">1.7.1.3</ecNumber>
            <ecNumber evidence="5">1.8.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_13019</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>nitrite + NADP(+) + H2O = nitrate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19061"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; sulfur metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.7.1.3" evidence="6"/>
    <dbReference type="EC" id="1.8.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767937.1">
        <property type="nucleotide sequence ID" value="XM_047912167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJA1"/>
    <dbReference type="GeneID" id="71992897"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13019"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050464">
        <property type="term" value="F:nitrate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="134"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO23571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="621" mass="68870" checksum="288F3AAB369AB8A9" modified="2023-09-13" version="1">MPPIRLQNTIGTPKRIAESLISISGPRTSARSLTTPSTKHVAQIAPGRCQELVWKGSRPRFPRRGVGTIRGTFHYARAEPQRAHAGGALALLFGASAIAVLAAPITTWVGDHVVDTKVETDAVHIDDGQVVAGIQKHRLADIAKHDEHSESKWVIHGTAVYDITEFVAGHPGGKVILRACGKSIDPFWKLFSIHNKPEVQKILDDFYIGEVDERDLNTDGHINWGVLGNDCDSCEDPFKDDPERDPELIVRTPKPFNAETPGQLLTDFLTPLRLFFVRHHLWVPKLEAAKHKLEIELSDGEEMAYSIDDLKRKFQQHTVTVTLQCAGNRRGHMNEAGNGKTSGLPWDFGAIGTAEFTGVRLRDVLLDSGYDVTAACMSCPDDPEADRHIHLCAPSDTYEQSIPLQTALNPASDVLLAWEMNGQPMPRDHGGPLRAIVPGSAATRSVKWVEKVRISCDESQSNWHSRDYKCFGPNVKAADLKQEDWDEAQSIQELPVQSAITNMKKKDDASVTLDGFAYSGGGRRIVRVDVSPDGGKTWRQACLRKDNAKGTRRWAWTLWNMEWPEDQLPKGDVEFVVKAVDEAHNCQPATFDGIWNFRGLLGNAWHRVRYSAGEAEPARPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJG9</accession>
    <name>A0A9Q8PJG9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768155.1">
        <property type="nucleotide sequence ID" value="XM_047911961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJG9"/>
    <dbReference type="GeneID" id="71992691"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12813"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="271" mass="30565" checksum="B10A0E31E112C566" modified="2023-09-13" version="1">MADLVDPCIKESALVVVHVGERKKDFETIQRGHLLSRTNIFSKQPVASPDDDTAAIIRILDTTADDLWYLVIYAGYLRRGSSTIQFPVNSEGHAKDEACYHVLVELCIFGGKIQDESFQDDVIDAILAKYSEGVAAVEPLEPDTIEEVYNQTMQGSPLRRLAVDMHLWVQFERRYIENDFEMCPKRFQQDFIMAVLDRLPNRELWLVQALIGGLRGNDASHHLTKMLNNIPPLPRGTVIPVTVSCCDYHLHAQGAICGNKKRKREAEEATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJU7</accession>
    <name>A0A9Q8PJU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768159.1">
        <property type="nucleotide sequence ID" value="XM_047911680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJU7"/>
    <dbReference type="GeneID" id="71992410"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12532"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="18670" checksum="C69237A579E5BE04" modified="2023-09-13" version="1">MAAVMWFKEATLFAISLAGPAIPPTIVTDGICLAGWQTYRARRLQQPPTIKHLDVVSVVLSGVTWVLFSQGSEEAYATKVAWCLWLSVWVNYIANTYLLVLVRYCRLTWSLVLVTISIYVVSSVVSTLIEANTSSETNASQTGLIDAVTICSVPGLSLPELGNGYPENGGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJV3</accession>
    <name>A0A9Q8PJV3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14 cytosolic factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768350.1">
        <property type="nucleotide sequence ID" value="XM_047911669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJV3"/>
    <dbReference type="GeneID" id="71992399"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12521"/>
    <dbReference type="OrthoDB" id="30289at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF3">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="108"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="641" mass="70805" checksum="FAC38ABFC4885437" modified="2023-09-13" version="1">MSSARQQEGGKLSRVESYQWPSGHAGHLSEGHQDQLAKFKQLCEQKGYYHPGHSSKNVPPSHDDETLLRYLRARKFIPKDAFGQFKDTEDWRQENQLDTLYDTMDVHEYEQTRRLYPQWTGRRDKRGIPFYVFEVANLDAKVVNAYANDSDRKKKGGQNASDSTVDVKSKVPRKMLRLFALYENLCRFVLPLCSAVPDRPNSETPVSQSSNVVDLNRVGLAQFWKLRAHLQDSSALATAHYPEILDRIFVVGAPGFFSTIWDWAKNWFDPITVAKISILSKSNTLSTLEKFVDRANIPKKYGGDLDWSFGDLPNLDDPALEAALKWKQDVKNEKGHKTFPAGPMKWEYTDEGDLVAVAIGSENGAPRKQELAQLHPSAGVARLALSPGRNPHSDLFKAASGQKPLTAVQSQGQHPEAKADQAVPAAAVSIPAAKAATVKHTTNGSIDKMTSNRPTDADLNIGKSPDSAVEPSSIAGTYTVPYRDHENQVSHPPVDARQGTSSTRFEQQSGTHAEGQLAHSTPHKREDGLQGEHAVMEPRTVGQAPKETPLVREEEPQPTIVEQAQEYAGQAVEAAKQVPATVLSAVGMGEKAEEVKPAEPEKKDDERVDALTQEQLEEFMREQSKSSIAERAVKQNAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK24</accession>
    <name>A0A9Q8PK24_PASFU</name>
    <protein>
        <submittedName>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71992579"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12701"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
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            <dbReference type="EMBL" id="UJO23913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="24352" checksum="ED060F6BDCE6E36A" modified="2023-09-13" version="1">MTTNLISRLPLELRLQIYEDCDCYPDSTCGRSYKDPWSDLPRSHDIGKRLDGVAMANLLSAFPELVSDMPEFLSELHGVKTLAFSNRYNPQTATTLPSLNSLCQILQIAPIKAELHIALDTRHWNHCLLSTLIGSLVQTRQTVHVSLICNSVPAKKIVAVAELLASRGGSVSIYEECACNCHRFAGIGPCTWINPVPRGLRMRPPFWFMLHETQHGGVA</sequence>
</entry>
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            <authorList>
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    <dbReference type="PANTHER" id="PTHR42085">
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        <location>
            <begin position="7"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO23940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="144" mass="16516" checksum="5A3E336F116525AA" modified="2023-09-13" version="1">MPRDVFPFLDLSAELRNEIYILSLQQPTPMHLEYLRGIRTSEKDNTSPRQSPPAKRELTCSLLRTCRQINHEATSILYGYNTFAPSLGDCSYLRLFLKQLGSCIKLIRHVELPSCYNARLPSVRQVFHLLKQAAMLESVTFSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="327" mass="37285" checksum="15BD64F71EE99CA3" modified="2023-09-13" version="1">MHFHHSHSDYTPVTPVTHTANCNMSCASRGEEAQYDIYPKQNLSHEQRQAVQQNLRNLVQDVEEKQHPVTGTVCWSTRLAKEHANLLKRSPEFNDHSPDTDTKLKFVSEHVTLIYARELLAAHETSLAPQQPTQNFSKHAGSHATPANMTGLDTAMNSPGTSRRPASTPAKICYFLDKIPPEGRLMIYEYHFATFKLDYSTIDIYTSLQPPLLNVCKLMREEALSLYEARIRESKGVVRETREIERQRADADYDARGEIFASKEEHVSYSYRVVKQMTASMKANRAHMVELARIQMVQDGKVDPELAEWLETTGRKHEAKMGWSIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL97</accession>
    <name>A0A9Q8PL97_PASFU</name>
    <protein>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">CLAFUR5_13499</name>
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        <name type="scientific">Passalora fulva</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    <dbReference type="GeneID" id="71993377"/>
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            <end position="234"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="3 4">
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    <reference evidence="3" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047913536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMK7"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_14388"/>
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        <location>
            <begin position="52"/>
            <end position="66"/>
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    </feature>
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        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="164" mass="17761" checksum="998ACEFA1EA572D6" modified="2023-09-13" version="1">MDGIIMIRELSLRQGSSWSPQRVMLAKLDPPKAEITGMEEETLSGKLSKATFDSKVETSAEEKSKSEPQSATSTDNNEEASAKPPVDAHDPIRQFGILLPPALRTAQNSFNSAVLNDDCIAKAVEAARGMRRVEAEIRKLRKEARKSERGERLRGAGGVDVGGG</sequence>
</entry>
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    <accession>A0A9Q8PML2</accession>
    <name>A0A9Q8PML2_PASFU</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="2" key="2">
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040280448" evidence="1">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO25198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="19926" checksum="81096A658158B8B8" modified="2023-09-13" version="1">MLLLTTILTLAATCLASATPLVDRDAGTDLLITDLLRLDRAIRTITTAANSFTGTAASYGAIRESISEVNRTNRIAYYDAMTIKPQSIPDSNRIIAVVANPIQPDITQAVDALIAKKDAIDKGGFMKETADGLNLISYDHDTLSLVAVAPKLSPVTIPAAAPPVLQIDLDWRRGVVAFGGVPLAPITM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQ91</accession>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987063"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VAST DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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    </dbReference>
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            <end position="381"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
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        <location>
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        </location>
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        <location>
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            <begin position="42"/>
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        </location>
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        <source>
            <dbReference type="Pfam" id="PF25545"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="485" mass="55833" checksum="47D7471733CAB5EE" modified="2023-09-13" version="1">MKRKRSILLSDGRKSPHEPPNSQHSPTFDQIEPCLGQKRRRSAEGKESEQLHEPWRKRNRAELEQSSQQDFNLSEGEPDEQDPIQYWASTGNWPNSFDQMSGPGSDGLNKRRRSSTPSYSSRAKDRSVPLAHTAAYEEELQRYGISFKDWETKDLETYMGIFQRASKCNEERVRRDLTPHIVPSAELLYILDGGHTLENIREEMSVDWTKCSLLGGTQPRPDYAYGLSSATFTEEERYKMENYTNVNNPTKFTDSMYFPFLMCEAKCGKKNINDADRQNIHSASIAVNAIIQLCRAGGEDRVRSLHGQILFFSISHDNERVKIYGHFPLIRDGRTTFHRYYVDNYSLDGHHGRDRNTGSNFTRAVYGKFYPQHLKRIRQAIACLHDPRTSSMMSDISVGGDETPASDQSSQERDSSRPPLRRAMSRGSQGELTLMKQQMAKMEQMYKAQLEQQKEESQKHVEQQKEDSGKQMALLERLLDRAQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQK6</accession>
    <name>A0A9Q8UQK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription activator AMTR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07359</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763230.1">
        <property type="nucleotide sequence ID" value="XM_047906507.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71987237"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07359"/>
    <dbReference type="OrthoDB" id="5418899at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="713" mass="78814" checksum="417A2F2B9F939E18" modified="2023-09-13" version="1">MAQETSTSVPSARACDRCRERRVKCDKRQPTCLRCEKLGRPCPGYDKKRKFVDEGVTLRKKYQPSSDMPPGGESSFSLQFLQPGVHGADGAQSQDPSPANVTGEPAAKSGTSSSQATAITTTTLPPDRFNSLQSIPLGLGGALNTGLPMVLDPTTEALLVNDGPMQIPLTDTHPTLDDLWKNEAFDPEFFDLEPDVYYATAGNTCGFLPDIPEIVDEVDQSDMLLNNSASATPGSTGFASTGLFSGDDALSNFWAPESQLNTSAKITHEREHEMAFLIRHFTDSIGPWLDLFDQDKHFTHLVPLKAIRDALLRNAIAAVAAKQLGRVRGQRPFASQQMQRPSAMESFDDHEVDWFYKAANYYDKAIAFSRQYLQAVSGGLSDPPSPNAQAALSMANSDDLLVAVSIFSLYESLDNVETGWMQHLIGLKSLLTAVSPSQQVQNQAVPSLTVGRLASFWNFARADYQAAYIKHKKTLLDTNDVALWNSCGLEIQHDGALYKSTDYVRNDPTHSRVLAELVAHTLLWLVLRVMNYIANDDDSSAARQGQWDQLTRQLDHWYGNLPATYQPCATIRHRSIPPTTSQLVESFFSIDVCAAALQLYHFARILLLLHRPMSRQNVFGGNRLKQYREVSNEAIKHAHEIIGIALGRPHPAIRVEMLLPLTVAGACLEENEERKVVIELLRAIEKDTGCATESRCQQLVIDWGWGTEPEGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQQ9</accession>
    <name>A0A9Q8UQQ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C6 transcription factor asaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_07313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763291.1">
        <property type="nucleotide sequence ID" value="XM_047906461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQQ9"/>
    <dbReference type="GeneID" id="71987191"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07313"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="212"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO18925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="594" mass="65844" checksum="2DBF1E06E6A8525F" modified="2023-09-13" version="1">MISLLEAQISELAERLSRVEGHVRSGSTTQSEVSRQSTNSSIRKQSSSGSEVDLSEMSFSPISARPASDRSLSLPFALKFNIRSDDQQYSTPERMTAMRDILVRNIDPLLKIVHLASIQYLFDTKCSEARSTPSDARALKFAICFAAAASQEPSDSNVFSSPSHGSPAKTYAHNFEISLLKAQFMSNPTVTGLQALTIYLICGAQFLDKTYVWSLTAVLVRLAMKLKLHRDPDSQQGLAYRDGEYRRRLWWHICSLDASTADARNTDPMVYERQCSTRFPAAVQNSTINQTVPKGSPETLFATHSPDMFHRLIRFEITYYTRTILFSDTCNEENDFPVLPADGKLSIIDSLEKTLEDKYYRRCHYKSATCRIAITSSKITVAKLKLKIRQASTACQKYFTSAGAEQTITACIEIVEVTQTLRTDPALASWTWLWPRDTDLDAATTSLQTLHQARTRPAITQKAWTAIDAFFANIKSDSDLIRDIQYSRLIALRNKAQKGKCKPSTVSPLGRSEGRARRKSMSIDVSGEEVVRSFSMPCDALGTMSAPTSAKHGTFDSVSSKTSGGTSAAWSAESAGPAWPLPGKRGSMVLDFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQU2</accession>
    <name>A0A9Q8UQU2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763398.1">
        <property type="nucleotide sequence ID" value="XM_047906677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQU2"/>
    <dbReference type="GeneID" id="71987407"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07529"/>
    <dbReference type="OrthoDB" id="3650565at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="452" mass="49792" checksum="4450C2F9F4427B92" modified="2023-09-13" version="1">MTIFRADGDLSKPFKDNVLQPRLRAAISSTMTGIAAAGSASKLDSVLSTLSAPDRQPVSFVPWTRQSNEDGGRARDSIPRQLTTLLDAPILEMLRANDNLLIIAEICSSNKHPMKDRQMWHPLPRNRPVYLLTVNPDRVTRRTGEVAQVLSRLDVRGGAWLTQGFPSGEAMDETNSEVMDKTDWQLVTQDTSSGLEAQLTLGRQRALQMGFYWRRDEVMIRLNNHVDRTGSSPRSLVALQKAPKVAIEVHEFDAVLLVARVSPTSQAKEDNSMNTSILRQSKFLSTVVAQCGVPVHSLNCTSVSAHSNGLVEILKSKLKTLNERVLVVSVGVDSLCHSSETYLDLVNMSYDGVGFGSLLWDHDTTVDVSLLERQRAPLLQVNLPLVQPLLWFLPGMGNNPHPTILHAERHVTKSSEWVEAVTLTSYQGGKSIAPEPMKTAGERGFSAGQMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US87</accession>
    <name>A0A9Q8US87_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764883.1">
        <property type="nucleotide sequence ID" value="XM_047910337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US87"/>
    <dbReference type="GeneID" id="71991067"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11189"/>
    <dbReference type="OMA" id="WEPIVIN"/>
    <dbReference type="OrthoDB" id="3518533at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040180330" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="192" mass="21366" checksum="1DB6C56F93E98BF8" modified="2023-09-13" version="1">MKYLTLFLALVAVATAYNNTTAEYKLQTRLKLADYSKQDFDGLYLGGYHVGAGQSDVVFSDEPPLGNASLAFTNVTANGTTYSNQLFDLGNDFPWGLVMVPIEQFYSAWQPVELNAGATGSRYDVTGFFINETGLQWTSSPEQVGTENDQFGGWLICDWWHGAPQLFFRISYYSGYEAPASCADVYLMPQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USU6</accession>
    <name>A0A9Q8USU6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765527.1">
        <property type="nucleotide sequence ID" value="XM_047910784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USU6"/>
    <dbReference type="GeneID" id="71991514"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11636"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="64"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="245" mass="27522" checksum="C6555EE73A153DF3" modified="2023-09-13" version="1">MSAAFPPSTMRPAHNFDRKVEDMKPSKSDINWVIMDYLVSEGYPGAAEKFAQETNICSPEDVDSIRERVTIRNSIHAGRLDDAIQMINDVDTEILDHNRALHWNLLQLQLIEIIRPILKTYGGTNPPSSEWVPVLQFATEQLAPQAPTHQDYQTALNNTMALTIFSEDKMPAETKQLLDLKLRETVANRVNKAILESRGQRSEAKIRQLVRARAWAEAQAREAKVDLPAFPIPIGLEPAGEAMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USW6</accession>
    <name>A0A9Q8USW6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxylase/desaturase CTB9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765573.1">
        <property type="nucleotide sequence ID" value="XM_047910298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USW6"/>
    <dbReference type="GeneID" id="71991028"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11150"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="325" mass="36962" checksum="FB3A495088BC5F5C" modified="2023-09-13" version="1">MSQVFWCRVERIDLPASHGLLDLMTVAMAQVESPRAVHTNLNYYLLPSDGGTKIFYPGTAGNYRRKHDPRPVVIEDIRGLEHVFKVDIHGFQVLKHPVSKKEYQDEEKIKSTAYAETADLLKEATGASRVHVFSHIVRSQAWDSVLEAGKDLGDKETQATRTSARFIHVDQSYEGAKEMLRDNLPPEEAERLSKTRWAILNVWRPIQQTVHREPLAVCDARSVPEEDLYPVRAQLPGKGSGSFEDASKGGTFETWQLRANPNHKWYYASELTEDEVLLIKCYDSKLDGRARRAPHTAFATADDYGPPRQSVEIRCLVFWEDQALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USY8</accession>
    <name>A0A9Q8USY8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase apdG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_11173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765601.1">
        <property type="nucleotide sequence ID" value="XM_047910321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USY8"/>
    <dbReference type="GeneID" id="71991051"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11173"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF15">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE APDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="140"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="248"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO21235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="420" mass="45726" checksum="1C2FFDBB31AF6D98" modified="2023-09-13" version="1">MTAESISFREPPYLSGQPSPYYTPALREWQNACRKFISTHFTPFAVEWEAKGEVPHHVFEQFAKNKFLVAAMPAPLPTAELKAAGIDNLLDVLMTTGICGPSCTINVSPGFGVPCLLRYGKAQLKQRFLGDLFWGRKKICMAVTEPEGGTDVANIRTSAVRSSDGKSCIISGKKKWTSTAMWCTHAIVGLRTRKAGPMGISLIIVPLKNHKGVKVERLNMAGQISNGVSEITFDQVHVPVENLVGIEGHGMKYIMTNFNHERLTIAIGATRQARVALSAAFEYALQRQAFGIPLMEQPVVRNRLAKAGVQLEAQWAWIEQTVFQLSHAAQSATADAEAGAIVAGVKANAGAVLKECAECAMVVFGGAAYSKDGIGSIAERAWREVFGQRISGGSEDVMLDFMVRQLARTVRQKERSLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT51</accession>
    <name>A0A9Q8UT51_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose N-acetyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765900.1">
        <property type="nucleotide sequence ID" value="XM_047908877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT51"/>
    <dbReference type="GeneID" id="71989607"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09729"/>
    <dbReference type="OMA" id="CRDREVW"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="395" mass="46059" checksum="9CB16A700222CDC5" modified="2023-09-13" version="1">MGEQYDDWGNPIVRPRYEPRDQSLIGTLRHFFTLAIRRYRTLLATGLFALCLLFYWNAAPRRTPKVPPTDWSRFAYVQYVTDNHNLCNSYMVFEALHRYGSKAERVMLYPDEWDLEDESPQDRNSQLLIRAQKLWNVKLRPVSLLDTDGKAQPGTLNAPSSWATSITKLRAFELGEYDRVLHIDSDITLLQHMDELFLAPKAPIAMPRAYWSDETKPQDWQLTSLLMLLEPNPLELRNFIDILMSWKMKPGFQVGKNYDMNLLNHRFGASAMVLPHRPYAMLSAEFRKHDHSAYLGTINGPRALQSKYEWDPDRALAEAKLVHFSDWPLPKPWVMWPHEGVAEMQPDCDGKPACRDRIVWKNLYDDFRKRRKDLCRILSVPAPAWSDLKNRTAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTB2</accession>
    <name>A0A9Q8UTB2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766019.1">
        <property type="nucleotide sequence ID" value="XM_047908262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTB2"/>
    <dbReference type="GeneID" id="71988992"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09114"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="94"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="27539" checksum="34D50294903F49C0" modified="2023-09-13" version="1">MAQAVIEAICTRRYEQQPRSILMSATPPLQDDSIQDASNAAEILPDNWPQNIVYLSDLKYTEAALELKPKLTLSPSDTGSWTKIPIELTRSPCSRVKIVTIGDQKHPAYGQRGLFAAENLIPDAFILPYVGEVHCNSLSDTNPHSDYDLSLDREIGLSVDSAYAGNEARYCNDYRGVAERANAEWRDCYVQVPSMRRAGGKRWERRVGIFVVSAGKAGKRTAGIKAGEEILINYGKGFWEGRKTLVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU26</accession>
    <name>A0A9Q8UU26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766832.1">
        <property type="nucleotide sequence ID" value="XM_047911605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU26"/>
    <dbReference type="GeneID" id="71992335"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12457"/>
    <dbReference type="OMA" id="DQQHEHI"/>
    <dbReference type="OrthoDB" id="1060854at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="497" mass="54909" checksum="7EAB69790B796426" modified="2023-09-13" version="1">MGSVVAANSFFGHHSSPSHPQHNVFRETTPRSTDTPDYHDYEYHDHDRSPPPSTKRSRAEANSHMSESAQRAPSSSAARSTPQQQIQRETPQQHAAAQTNARAESQAAQHNAPPPPSPSLAGRLAPPTRDGSQTLRPQATGTPTAAERPSRSRKIKVRDLEHIQSFATEDMRSFSEIRSRSRSRSRGAEDDGPQFEISEMKVEHVIEMVAGLLTKITTTNDRQHEHLHRQPPTIDAASHLPQQTSSVLAFHGKNVPSITILSYLSRINKYCPTSYEVFLSLLVYFDRMTERVNAGPMQSLRDQQAQSVREQSRNSSAESLESDRMEGVTATTPSGTQQVTPPHSGTLGKSAQRGAPGTPHSRPTQPESPSIPAEPTTIDPYNLSHFFVVDSFNIHRLVIAGVTCASKFFSDIFYTNSRYAKVGGLPLPELNHLELQFLLLNDFRLSVPVEEIEAYGTMLVEFYAREVVAQKQAAEAMQMRSLSESSEDSVATVRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU58</accession>
    <name>A0A9Q8UU58_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MCM7</name>
        <name evidence="14" type="ORF">CLAFUR5_12450</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU58"/>
    <dbReference type="OMA" id="AQHVTYV"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="394"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO22614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="810" mass="90094" checksum="4EDCC23E9C078373" modified="2023-09-13" version="1">MSLLTYKSIVNYEEQTTAFKDFLQNFKSSSTETEDALGDLNLDGDGTSDKYDFMDDADDGARTRSRTKSKLKYMNILQDVADRKSSQVLVDLDDLNEYERSLDEESVSALKLVSSIEKNAQHYIEILSRAADSVMPRPTREINFKDDVLDIIMSQRSKRNETVLQQQEGQIEGELPESIFPPELTRRYTLNFKPVTPSGSSSEKGAKALAVRQIRGEHLGHLITTRGIATRVSDVKPSVQVNAYSCDRCGHEIFQPVTTKQFTPLVECTSDDCQKNNAKGQLFLSTRASKFLPFQEIKIQEMADQVPVGHIPRQLTIHCHGELVRQVNPGDVVDIAGIFLPTPYTGFQAIKAGLLTDTYLEAQYVHQHKKAYDDMVLAPTTIRRMTELERSGQLYEYLSRSIAPEIFGHADVKKALLLQLIGGVTKEMGDGMRIRGDINVCLMGDPGVAKSQLLKYITKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGTCCIDEFDKMDDSDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNPRISPVENINLPAALLSRFDVLFLLLDTPSRDADEELARHVTHVHIHNAHPEPQGGGLIFSPNEVRQWVARARSFRPVVPKQVSDYLVGAYVRLRQQQKRDEAGKKTFTYTSPRTLLGILRLSQALARLRFADEVITDDVDEALRLVEVSKASLYDDNKDRRGDQSASTKIFNLIRGMRESGAAATGEGRGELDMRRVRERVLAKGFTAQQLEAAVDEYASIDVWQTAAEGTRLVFIESGEDDEDMGDEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUV3</accession>
    <name>A0A9Q8UUV3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase himC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_11704</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767641.1">
        <property type="nucleotide sequence ID" value="XM_047910852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUV3"/>
    <dbReference type="GeneID" id="71991582"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11704"/>
    <dbReference type="OMA" id="AKNPRIW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602402-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO23275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="520" mass="58904" checksum="69BD549F1AF129DF" modified="2023-09-13" version="1">MDFLSNLPHAAKAAIGLAAVYAVYQLLTTITLWAGRRDFKRERGVLDAPWLPQRDRFYGIDLFLDNIKALKEHRFLELGYKRFTETGLNTMQLVALGRHMHMTTEPENLKTIQAIDHKKWGLGKRRKIGFAPLLGAGIFTTDGAEWQHSREMLRPNFVRSQVGDLATFEKHVSNLIAAVPADGATVDLSDLFFRLTIDSATEFLFGESTESLTKNSSEGFAEAFTYSQDFIAHRSRWGMWAKLLKANDRFEKDRKFVHDFVDYFVQKGLAKRDTLLAEKGKAETSGRYVFMDELVRQTTDPIRIRSELLNILLAGRDTTASLLTNTWFMLSKRPDIWTKLQADIATLNGAKPTFEQLKNLKYLKALLNESLRLHPVVPQNSREALEDTTLPLGGGPDGRAPIFIKKGEIMAWNVYAMHRRKDYYGQDAEEFRPERWLDDPDTGKKGLRPGWEYLPFNGGARICLGQQFALTEASYATVRLCQAFAGIESRDEEEVWVEHLTLTCVSLNGARVGLTSRGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVA9</accession>
    <name>A0A9Q8UVA9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768048.1">
        <property type="nucleotide sequence ID" value="XM_047912393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVA9"/>
    <dbReference type="GeneID" id="71993123"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13245"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="26"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="57813" checksum="EC4FEECA21FCF1A8" modified="2023-09-13" version="1">MSPEDEVLSSDLADLHRAWAKHGWKKIEHTILQANAHGLQWVWADTCCIGKSSSAELAEAINSMFRWYRDSAVCYVYLDDVPDITEALIRHTGMEHGSRDILKPDHTFLSDYKRRDPVSYLSNAATWICKDPPVQWLEVTHARWFTCGWTLQELLAPHDVQFFSQCWEYLGHRGSMAHLIAQACNIPRKVIIEREWLTARHLDPGSSTMRLYATIEHVLLQALREKVTAFFEEFSVAQRMSWAAGRRLTRIEDEAYCLLGFSDVNMPVLYGEGPRAFLRLQQEILRTRIDHTIFAWDHVQGDLPRGPTKQALLAPSAAGFRNRGNTTQAQFDLRCVHEVNNVGVRMQIPCHALPIYDGINGKIVGDHASREVLALIHCYSGDWLIMLALRLRHVGATDQEIFVVEGDFTHKRITEVDAVTASKFQYNSVTILFSNSMLGDFMSPFPNPFPDDTRIGIRVAIRLEGRRVDLEDTDLACASVSSDSSDARSKVTNDSSHVPGLFFQEKIAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVV4</accession>
    <name>A0A9Q8UVV4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter prlL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768618.1">
        <property type="nucleotide sequence ID" value="XM_047912590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVV4"/>
    <dbReference type="GeneID" id="71993320"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13442"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO24252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="519" mass="58303" checksum="6BACFACC6DAA3F5D" modified="2023-09-13" version="1">MSNEKDTTKADNILAAPKVEATALRSHSIDEHAQDVAGYDHDLMSARTLLSYEEERKLLRRVDWHLMPLCALIFMVKNIDANNAANARIMNRGTSRNILTELGMTGDEYNFVSTVYFIPFIVFEIPSNLVMKKMLPSRFQSDLGHCPSISCCCIVEEWLVYARFFLGLCEAGMFPGIILQLTYWYRADEMTMRLLIYCSLEFFANVVSAVLAFGFDHISGRGGLSGWQWFFLVEGVITIAFGALLWFVLPDFPEQAKWLSDKEKAFLQARLPANAPRSSEMNFNWREVIETLKDQRLWLFTLVFIAKTVGASDLTFYLPTIVADLGLTSIAESQLLTIPASVLPIILIAIASLLTTRFNIPLPLIPLTYMTITLAMYAILHTYPNNGGVYAATIIAGGLGNAWYPSMWPWRLQTTSKATGNAFAIAFTNSLGGIGSLIGPQIFRMKYAPKYGVSFAVAMAFTGFCVVMTGWTWWVTRLTERRTREIRRERMKAGLKGEVVLGDVDIGADLERKRRRGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVX1</accession>
    <name>A0A9Q8UVX1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_13446</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768736.1">
        <property type="nucleotide sequence ID" value="XM_047912594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVX1"/>
    <dbReference type="GeneID" id="71993324"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13446"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016237">
        <property type="term" value="P:microautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14474">
        <property type="entry name" value="SPX_YDR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="738"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="768"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="524"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="648"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="531"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="656"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO24370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="794" mass="88808" checksum="9D1867105A3606C0" modified="2023-09-13" version="1">MKYGETLRQRSIPAWSHHNIDYDDIKNFIKENTTPGKGKTLSVPGRGDDKLLQFENSLFHILVDQHQRIHLFVRSKAGEIQRRLDHSKKQLRQLAARQSKAADSRIPVGRLERYGKLEDDVIKAGEEIKSLARFVATQRTAFRKLLKKYKRWTGSTDLDDRFRDEVLENPKSFANLDLGPMLDDYSATQQSVRTLYERQMKKSKGNESSCEVKRPAPGSSAIRQLREAVQTGSKVFFDSSLATVPLGENGTFASYFVHPENVVELQMLLLQYSHFYLSRSRPSSLAPPITPDSPNASFGASGTKFVDYHILAADNLERFAKEQSALTVNDREHLPNSFPQRAKACVRWNNDEDALACLRSRSGQTKSAYLKRKHIHDFFDQGAEFAAKQEATLADSAETVEELRRELLRDNIKPLFQYSSCRTRLVGLEDESDSMTLATLDTSITIQEAGAVDGKSKSSFPFALLLVRQEGTKSQLLSALDASYLVERVRGFSLEYHSIWQTHRPANIAPPLWLPILDRDIRKLPPPAMKRTSSAHGSGAQTAGSNGSITAGTGTDSATAVETTSQDAPAEFEAPPLKSFRKKRKRRSYPRNEEQQPQRYWNEFDHPEDGDGDAFVIYIDPNEQNRFDRFFDKLGSLFRLRSKTAEEELLIPSSPPEEESSDEETETSPVKNKIKKSNAQSFGTFASSSQSPALNSKREQRASFFGQVAATCYAAALAILVVAYILRLTGRHKFINEVHYGVLFAMLSSLAFAAIGFMSVLRSGARGYVTWAISAAVLIIDVVGSGALLAWVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW84</accession>
    <name>A0A9Q8UW84_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="1">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_13900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="1"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769112.1">
        <property type="nucleotide sequence ID" value="XM_047913048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW84"/>
    <dbReference type="GeneID" id="71993778"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13900"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000050">
        <property type="entry name" value="Asparagine synthetase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="5 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="11">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="392"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="13">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO24746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="605" mass="68341" checksum="3C636E654475422B" modified="2023-09-13" version="1">MCGIFACHQHPDVQKFRPTAIRMGKQVKHRGPDWSGNKIANNTILVHERLSIVGIDTGSQPITNEDDTIALAVNGEIYNHKILRKQFAKPYPFKTHSDCEVIIPLYQEHDVDAPKYLDGMFSWVLHDKKQDRLIAARDPIGITTFYIGRSSQTPGAVYFASELKCLHPVCDNIEAFPPGHIYDSKTDKMTRYYTPKWLMEPTSIPTTPLDLKLLRETFERSVRKRLMAEVPYGVLLSGGLDSSLVAAIAQRETHRLQKEYARQQALASGTASPSMDGVANGVVSQTENGIHEEDLAGIDEDYHLTSVPLLSQLNSFSIGLPGAPDTKAAQEVARHLGTRHHSFTFTIQEGLDALYDVIFHLETYDVTTIRASTPMFLLSRKIKAMGVKMVLSGEGSDEIFGGYLYFHNAPDKNAFHEETVRRVKNLHLADCLRANKSTSAWGVEARVPFLDKEFLEVAMNIDPAEKMIDKSQGRIEKYIMRKAFDTEGEPGAKPYLPKHILYRQKEQFSDGVGYGWIDGLKDEAKKQVTDEQMVEATIRKDKPHWGDDIPDSKEAYWYRCMFDEHFPPYCASTVMRWTPTWSKQTDPSGRAIESHEQAYKPGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWA7</accession>
    <name>A0A9Q8UWA7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Communesin biosynthesis cluster-specific transcription factor cnsN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_14495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769215.1">
        <property type="nucleotide sequence ID" value="XM_047913643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWA7"/>
    <dbReference type="GeneID" id="71994373"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14495"/>
    <dbReference type="OMA" id="HIQADDW"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
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        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="780" mass="87136" checksum="1F6CE8235BFD9A8D" modified="2023-09-13" version="1">MALPTHHAHPPPPPLPIPHMGSFHTPQQVSPPGPQGQQHPGSAGDATDRARARAYKSRNKRPCDFCRYKKAACHLEANPPCELCIRFNKECTFVESPAKRRRPNEQTTENHKAVDGVFKHGTNGSIDSSAQFSNGGINGMDMQQDIMPWESNMTPFEMPGMAMNGGGMQQDFPFDPQLYHAPMNFETFEPMSASTSNGNTLAHKFPDHHQARSSMGASSPQSQPSSLPANLQLPFDSTSGEPSLDRQNSSNAQIVGISGESDPYLLSKYRYDEYNEATFQSVRMRKMNSGPGENDSTIPTFFMIQHNALASKAQPQDKSDTQDRWRRELEDIVSDEIGKRLIRLFYKYVQPYFPLLSREGGARDVDGVQVPREIPPCVLAAIYGHALPFCAWDEKLCVEVYTPPSADALFKIAWQSCQPLLHTPSISVMQTLLLLVQRRPTNRHVSDTPFKWVMMSTAVSIAQALGLNRDPTDWPIPSWEIKQRKHLAWAVYIQDKWLALNFGRSSHIQADDWDVPPLTHDDFPEVDRRSDDFGDSRADSAVQHFIKLCELTLIVDDILRDLFSIKATRQLHKSLEATLEVAKPLRIRLTEWYQTLPPGLLPDQPSGTSSMGSSDSNHRRKLMQLELDGNGSLQLAYITAKMELFRAMLRSRVTDSNAAAVTALRTGALAVAKEISDFLECLNARELEAFWASYSRTNFTIASSFMLLLFVTSPGVADAKECLGLLKAWRSLLRIKSRSCDLLNLALLRLDGVFVAGMERLIELSPAAQQAWVDSGQGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWE3</accession>
    <name>A0A9Q8UWE3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769173.1">
        <property type="nucleotide sequence ID" value="XM_047912998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWE3"/>
    <dbReference type="GeneID" id="71993728"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13850"/>
    <dbReference type="OrthoDB" id="3650170at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040495441" evidence="2">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="17642" checksum="B3563FA8E57A8A79" modified="2023-09-13" version="1">MFAKLTTVFGLLAVAAQVVVATPPACVIAAVNQAPDPADIKAVCDNDKVKNYISTKCGDNTDAANKYYADVCKDAGVTVSTSKSSSKSGSASATGTHGGSHTTASPTETLSGMPTGTAGTASSGFHTATTNGTWSAPTGTGGSSASQTTGAGVAESTGAASRLGMDVVGLAAVGVFGAMLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWK8</accession>
    <name>A0A9Q8UWK8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_14553</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769487.1">
        <property type="nucleotide sequence ID" value="XM_047913701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWK8"/>
    <dbReference type="GeneID" id="71994431"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14553"/>
    <dbReference type="OMA" id="EQSYLCY"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="10"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="523"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO25121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="549" mass="60558" checksum="795AB6D52CC46D16" modified="2023-09-13" version="1">MWKVGNIYVITAVAVIGGGLFGFDISSMSAVIGTRAYLCYFNQGPRGPPYNNDLECSGPTASVQGGITAAMPAGSWLGALVSGYLSDIFGRKKSIMIGCVIWVIGSTIICASQNIGMLIAGRIINGFCVGIESAQVPVYVSEIAPPSKRGRLVAFQQWAITWGILILYYISYGASFIGGQDSTNYSTTVFRLPWGLQMLPAVLLFCAMFFLPESPRWLARKDRWEDCHAVLTLVHGKGNPDSPLVRQELSDIREMAEFEARNKDVTYWELFTPKYINRTHIGVFTQIWSQLTGMNVMMYYITYVFAMAGYEGNANLLASSIQYIINVLMTVPALIWLDRWGRRPTLIIGAALMTTWMFANAGILATHGEVVPGGLNGVAAVSMRLSGAPAKGLIACTYLFVASFAPTWGPVSWVYPPELFPLRVRGKAVAFSTSANWAFNTALGAFVPPSFVNIRWKTYIVFGVFGLCMLIHTIFMFPETAGKTLEEIELIFEDPNGIPYIGTPAWKTKVDYSKARAIERGELTREGKLHHDDQSPVRVTEEPKRQESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWR5</accession>
    <name>A0A9Q8UWR5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450 monooxygenase TRI13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_14385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769636.1">
        <property type="nucleotide sequence ID" value="XM_047913533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWR5"/>
    <dbReference type="GeneID" id="71994263"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14385"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="574"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO25270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="628" mass="70467" checksum="DC186AB8D3CC26FF" modified="2023-09-13" version="1">MSSFEAYSDLLRPWSWSNNSPPTTADLGKTELHHADTQNSSTNWSVYIYALLAVTLVYGLYNLYRAALPKPVPGIPCDNASRNRLMGDLPDAMKWMGERKEFWSFMQERCRQLNSPIVQVWMQPLGRPFIVISDYLESRDIMVRRTPQQFDRSAWLGDMFWAIAPRNMTRFLTNDDWKVHRRLMADAMSPNFLKNVASHHAHSGASSLIALWKSKMDLAQGHAFSVLEDVCKAGMDTMWASTLGDEISTTSSQVKLISGLKSIPLPASKDIAAEFPEAEDPEAFTALLALGDSVVYAASSPFPKITHWLAVHLVSSLRKSMRLKGTLFSGLLNSAARKFATSQDESRVKHVLDLVVQREVSLAKKEGRQPVFDTQDIRDELFGFLLAGNETTAATICWGVKHLADNLEVQEKLRKHLREYHAAAFEQGEIPTSQEIVAANIPYLEATITEILRLAGSTPGNSRKTTQNVQILGYDIPKGYDVLMVSQSDQNHVSMLTQSQLSNGADYISAPLPIDLNRRSKRSVEANDVTGMWDPSNISDFMPERWLVADEKGEVSYDAKAGPFQAFGAGLRGCYGRKLAELNLRTFFTLIMWEYKVLPPPDAYRSYIGLDKAMHQPQQCYLRLEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWS2</accession>
    <name>A0A9Q8UWS2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769651.1">
        <property type="nucleotide sequence ID" value="XM_047913703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWS2"/>
    <dbReference type="GeneID" id="71994433"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14555"/>
    <dbReference type="OrthoDB" id="3627975at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="18434" checksum="2C5A1060F994630E" modified="2023-09-13" version="1">MCAQFDRRVAKTHKPTKNQTLKFPIDTSRIQATDKMLSTTILFALTLTGALAAPAPALEARGEIAADQSSCKGYQSTWNMNESIYQVVVGRPYLGGDRCPEIKSKVSAIYDLKRLKCSGSSKNKNTKLTIVSNMSQDNQYNINKALHNAYPEITFNCDTNLSMDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXR6</accession>
    <name>A0A1P8YXR6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell wall mannoprotein CIS3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00907</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">0WU</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943127">
        <property type="protein sequence ID" value="AQA29298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757182.1">
        <property type="nucleotide sequence ID" value="XM_047900055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXR6"/>
    <dbReference type="GeneID" id="71980785"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00907"/>
    <dbReference type="OrthoDB" id="5415592at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054508">
        <property type="entry name" value="PIR1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051153">
        <property type="entry name" value="Yeast_CWMannoprotein_PIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000420">
        <property type="entry name" value="Yeast_PIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254">
        <property type="entry name" value="CELL WALL MANNOPROTEIN CIS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254:SF2">
        <property type="entry name" value="COVALENTLY-LINKED CELL WALL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00399">
        <property type="entry name" value="PIR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22799">
        <property type="entry name" value="PIR1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50256">
        <property type="entry name" value="PIR_REPEAT_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573462" evidence="5">
        <location>
            <begin position="17"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall mannoprotein PIR1-like C-terminal" evidence="6">
        <location>
            <begin position="69"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQA29298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="298" mass="30073" checksum="B9181BFB63242BF1" modified="2017-04-12" version="1">MQYALTAVAFAAVAMAMPQGKAPPMPASSECQASYPGTFQIQVVNVTSSSNMVKRQDQSGTLRLTLNNGVLKDEQDRTGNIVANNQFQFDKPIQDNAKITEGWAACPNGTLVLGSDAVFKQCLSGNFYNLYDENGAGQCNEIYIQIINGGGAASAAPSATSAASVTQIGDGQAQAATSAAPVTQIGDGQVQASTGAVPVTQIGDGQIQAPTGSPVTQIGDGQIQAPTGSPVTQIGDGQIQAPTGAPVTQIGDGQIQAPTNGTSRPMPSVQPYTGAAAIPTAVGSAFGLAIGAVAMAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXU3</accession>
    <name>A0A1P8YXU3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycoside hydrolase family 92 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_11622</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">0WU</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943162">
        <property type="protein sequence ID" value="AQA29333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765118.1">
        <property type="nucleotide sequence ID" value="XM_047910770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXU3"/>
    <dbReference type="GeneID" id="71991500"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11622"/>
    <dbReference type="OMA" id="TMVNPQN"/>
    <dbReference type="OrthoDB" id="449263at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1610.10:FF:000002">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.10:FF:000010">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2080.10:FF:000001">
        <property type="entry name" value="Alpha-1,2-mannosidase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.60:FF:000002">
        <property type="entry name" value="Glycosyl hydrolase family 92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF25">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040671805" description="Glycoside hydrolase family 92 protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="270"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQA29333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="775" mass="85503" checksum="05DF2C2C1DD7CE6F" modified="2017-04-12" version="1">MGRFLTLVLLARTAVAQVGDPLKYVNQLIGTTNGGNVFAGATLPYGLAKAVADTNSGSNQGGFTTDGASITGFSSMHDSGTGGNPSLGLFPLFPYASCANDNINGCKLPKIARATPFVNDSVQAAPGYFSLQLEGGIQGEMTAAQHTSLFRFTFPEGGSPAIILDLSDLSDSRQDNASISVDDNGRMTGGAKFQPSFAQGNYVAYFCADFQGSIKESGIYVNSRGSADVKDLKISRSINGYPLPGGGFVRFTDSSPVLVRVGLSYISSEQACQLAEDEIPDFDFKKTRTTATDIWRRKMSPIDVSTNGIDNSVLTNFYSGIYRTMVNPQNYTGVNPVVSADTIYFDSYYCIWDLFRSQMPFLTIFDTPALVEMIQGLLTLYQVQGWLPDCHMSLNKGYTQGGSNADVVMADAYVKLNKTAEIDWDLVYEAVVKDAEEEPYDWCCQGRGGLDSWKRLGYIPVQDFDYKGFGTMTRSVSRTLEYSYNDFCISEIARGRGNLGDAEKYEKSSENWQNLFKADQTSNLINTTQDTGFVGFFQPKYLNQTWGFQDPLYCSNLDSGGSCSLQNTAGETFESSIWEYSYYVPHDQALLISTLGGPETFVRRLDYLHDRNITYIGNEPAFLTVFQYHYAARPALSAKRAHFYVPAYFSPTNGGLPGNDDSGTMGAFLAFTMMGLNPVPGQDVYLITPPFFESVNITSPVSGKVATIRNEGFDPSYEAIYIQRATLNGVPWTRNWIDHSFFLHGMELVLYLGRKESMWGRRTEDLPPSLSEYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L514</accession>
    <name>A0A9Q8L514_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-methylsalicylic acid decarboxylase atA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_01850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755366.1">
        <property type="nucleotide sequence ID" value="XM_047900998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L514"/>
    <dbReference type="GeneID" id="71981728"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01850"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="60"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="190" mass="21361" checksum="B823E85978A90A33" modified="2023-09-13" version="1">MFFITVSGSAPDGWDSSVWKSEIDREHLERTFEGWDEKLKTGAIDAVMTSGPGVTFNQWESAPAPTYHRGRICMMGDAAHATSNWLGQGAAMAMEDCAVLVKLFELVEDREDVDAAFEVFDKVRRGGRADMVIAQSRLLGQILTGQKGLDRVAVKEHDIQAKREEIRLYDVTEQLHEAQDCFRKLKLEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5C8</accession>
    <name>A0A9Q8L5C8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Very long-chain fatty acid transport protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Very-long-chain acyl-CoA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CLAFUR5_00370</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755551.1">
        <property type="nucleotide sequence ID" value="XM_047899518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5C8"/>
    <dbReference type="GeneID" id="71980248"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00370"/>
    <dbReference type="OMA" id="VWRQFLD"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000019">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="13" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="20">
        <location>
            <begin position="87"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="21">
        <location>
            <begin position="521"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="UJO11185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="649" mass="72639" checksum="47EBA5EA74AFC80B" modified="2023-09-13" version="1">MPRLPIPRSLAELPLSKTLPAAAAALAYLNGKYTLTKDVWGITNALRFAAYHGRLEKQDRINQFYRFEEWATNPKSAGRVFLAVPQDEAHPGARTEWTYAEAYDIVLKYARWLKEELGVKRGEIIAMDFKNKPQFIWMWFALWSLGAMPAFLNSNLRDNAFVHCVKISTTRLLILDHELQEALTDEAKAQFGADEKGRAIDSVILDEKLESRITSLSPYRAADEERSGATATSPAILIYTSGTTGLPKAANVSWTKPISGEFFFSRILGLTAEDRYFTAMPLYHSSASILGVSQVFGPGCTIVVGPKFSPRSQMKLATETKATVMQYIGEMCRYLVTSPPSPYDRAHNLRLAFGNGMRPDVWQKFKDRFGIQTVVEFYGATEGPGVSFVYSNNDFTRGAIGQQGLISRTIFGANQVLVKHDHETDLPYRDPKTGFCTKVKSNEVGELIYPLDPANINDKFQGYYGNDKATTGKIISDIFQKGDVYYRSGDLQRRDEDGRWWFVDRIGDTYRWKGENVSTAEVSEALGSHSALQEANVYGVQLPNHDGRAGCAAIGLPEGRTLDDALATELASHTRKRLPRYAVPLFLRVLREFEVTGTLKHQKVSLRNEGVDPSKTGDDILFWLPPNSDRYVKFGKNDWERIAGGSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L671</accession>
    <name>A0A9Q8L671_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_01498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755850.1">
        <property type="nucleotide sequence ID" value="XM_047900646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L671"/>
    <dbReference type="GeneID" id="71981376"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01498"/>
    <dbReference type="OrthoDB" id="3640077at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF8">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="34193" checksum="D7667DCF19B3375F" modified="2023-09-13" version="1">MANNLRVTDLAVNLQSLNMGATDTAAWNKHITSTCTIKPSFLTLPQELRDHIYSFLPLVTQDDYVRVGRRQDDNWDPMLLTLGAGCRELKQYNTLAATCRITYQDASKIFYRHNKLYVLHQVEHKEPIFTITAPSWLRRSSLAKDSNIIPSCRISTLRIWGTEREIQGERSWDSSSYYPALHVSWCVESGCYKVTLSLETPSRLDKLEKGIWEDMMTEATKVVIDRINHYLAEKQHMDADTVEMVAKHWVYAQQLMADETGVYNGYVLDYNEDVRFETVDTPSGPMWFLHDDRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6D5</accession>
    <name>A0A9Q8L6D5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756002.1">
        <property type="nucleotide sequence ID" value="XM_047900379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6D5"/>
    <dbReference type="GeneID" id="71981109"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01231"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="227" mass="25403" checksum="0685DBC8033B899C" modified="2023-09-13" version="1">MFFDIPAQTFMEQSLIWDLANVFTRAAKASKWSPLTEAAIDAKAKEFAEWRKLNQAKFDAVGLSIQDLMTALDSMAPQVYADWEAYKERVAAEKDARKKADALAVAGSSKQKTPATGSSKTGGPPQELVNYVGNFDDEPSSRDQAKLWCRFLNLLLYNVGLAVYRARLKEYYAPTGKTGVSFPTQEDINRSFANIDDTDTEDEFGGEIDLDVIDIERPQSPLSRRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6I4</accession>
    <name>A0A9Q8L6I4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_02302</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756133.1">
        <property type="nucleotide sequence ID" value="XM_047901450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6I4"/>
    <dbReference type="GeneID" id="71982180"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02302"/>
    <dbReference type="OrthoDB" id="1907495at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="12">
        <location>
            <begin position="27"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO11767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10013" checksum="4006387271A8943D" modified="2023-09-13" version="1">MAPRIPRLHTSSLTSTTMAKQIKVTAYQERVCSLLQQIPQGKVSTYLALSNALDSSPRAIGGALRRNPFAPEIPCHRVISADGYVGGFKGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6S7</accession>
    <name>A0A9Q8L6S7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756281.1">
        <property type="nucleotide sequence ID" value="XM_047899577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6S7"/>
    <dbReference type="GeneID" id="71980307"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00429"/>
    <dbReference type="OrthoDB" id="79687at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14011">
        <property type="entry name" value="PK_SCY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="910" mass="97757" checksum="5EF10DFC9BCFD6DD" modified="2023-09-13" version="1">MFSSALKSFSSNISSNYTIAPQPSSTAGPWKIFDAKRKQTGKAASVFVFDRKSLEAPGGGLGGRGGASSVKRAHDEVLARLKQEAGALARLRHPSVLELAEPVEETRNGGLMFATEQVVSSLAGLLQEKDDRERSAGRASRVVVEESDGTRKRRELEIDELEIQKGLLQLGKGLEFLHESAGLVHANLTPEAVLVNAKGDWKISGLAFCRPHESSTSATSFHPISLYEVLNHDPRLPGSVQLDLDYTSPDFVLDNTLTASSDMFSLGLLIVALYNSSHKSPLNVGGSLSSYKRLFSSSTSIPTQSNNFLVPSSHTLPPKLSSELLPRLITRRPAQRMSAKEFQQASYFDNILVSTIRFLEELPAKTANEKSQFMRGLPRIMPQFPKHVLEKKVLPALLEEMKDKDLLALIMTNMFAMVGAMPTGKRAFTERVVPKLREIYITNRSAEKDTSKEAGLMILLENMQTVAENCSGKEFSEDILPIILLTLESPTHALVDAALNTLPFVLPVLDFSTAKNELFPVIANVFAKTSSLAIKIRGLEAFYTLCGGAANADDTNDDLNGIGIADKKKSNASNSVILDKYTVQERIVPLMKGIKTKEPGVMMAALKVFRQVGEVADSDFLAMEVLPILWSMSLGPLLNLQQFQGFMSLITNLSGKIEREHTRKLQELSSSNGSVGVARSSTAGHATASTSAMNGLSNGDEADFESLVSGRKAAQNKDLMNDWGTAAAVPANPGNASSTQAPTFSWQTSTPAARPSKPMNSSLRPQAAPQRAITPDLASFSALTPSSQYSQPLPPSRTPSGSTASTIPIRPAQPGMSGSTTAGSSIDWSAATKSSSSAWSTQPPSLNGSRTTSGFSIPPPPTSPHNVTQGGYNFPGPKASVGKPQQQPQQQNRGGGMAAESGLDRYESLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L708</accession>
    <name>A0A9Q8L708_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF726-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_00460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756432.1">
        <property type="nucleotide sequence ID" value="XM_047899608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L708"/>
    <dbReference type="GeneID" id="71980338"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00460"/>
    <dbReference type="OMA" id="FAFIPIR"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="644"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="708"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="649"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="742"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO12066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="769" mass="83916" checksum="2B16A1FC655E8AE1" modified="2023-09-13" version="1">MSSMFSKATAALKGQSNASANSEDGESLTTVLKTEDDRSALTILIADCTEAMRKVIVDAFDAKETGKKADLIANVESEESENDAAAVLEEDVMGQTQKDQKEAADLKQKQEKELAQREKELSAEKMQELNAAALKHFDDWRSAVMQRVGEVVNSREVADEQKKHAAPKKETGDQEQQMAPPMKFPDLPKYDEGVQHSMLQLYPPVQNTLRSLPEEKRAVILHSVLLLLLSLENYQAHSRVLLLHLSTSLHLPIEFLATDESKVARVLLTAAESMNADEETKKAAEENKSGRKWKVGLATVAGAALIGITGGLAAPLLAAGIGTVMGGLGLGATAAAGYLGTLAASSVLVGSLFGAYGGRMTGKMMDQYAREVEDFAFIPLRDHHKPRKIENEYRRLRIAIGISGWLTNQDEVVEPWKVLGAQLESFALRFELESLMSLGNAMTTMVTSAAWSYAKVEIIKRTLFGALTAGLWPLALLKVGRVIDNPFSVANYRAIKAGEVLADALINKAQGERPVNLVGYSLGGKVIYSCLQKLAERKAFGLVESAVMIGTPAPSTAADWRMIRSVVAGRVVNVYSTNDYILGFLYRSQSVSLGIAGLQAVENVKGVENVDVSDTVNGHTAYRFLTGRILKQIGFEDLDVEGMEEEEEALKLQEAKDEMERERAESEQTGSGEKEVSDEDVQKLEKQIEEKNEQSYVGWAQERLVATGTSASQALQKAKAQWYQKTAGKPANSDLQNDEAAADAKEVEIPPALRERPKHADVKRKPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7N2</accession>
    <name>A0A9Q8L7N2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidase FUB9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Fusaric acid biosynthesis protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00365</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756663.1">
        <property type="nucleotide sequence ID" value="XM_047899513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7N2"/>
    <dbReference type="GeneID" id="71980243"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00365"/>
    <dbReference type="OMA" id="PEMQVWV"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000056">
        <property type="entry name" value="hydroxyacid oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF149">
        <property type="entry name" value="2-HYDROXYACID OXIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
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        <location>
            <begin position="7"/>
            <end position="400"/>
        </location>
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        <location>
            <begin position="192"/>
            <end position="239"/>
        </location>
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        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <position position="33"/>
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        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
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        <location>
            <begin position="86"/>
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    </evidence>
    <sequence length="407" mass="44916" checksum="844CF811C02DBBFA" modified="2023-09-13" version="1">MAAAANVHDINCLTIEELETHAHSMMDKQTRDYYNEGADSGSTLKENTTGYQKYRIRPRVLRDVSAVDTSIDIFGHRNSMPLGVAPTAMQQLAHSDGEEGTARACKKMNVAMGLSSFSTKTLEKVATASEDNPNVLQLYLFEEKEHSRKLIQRAKKAGYKAVFLTVDTPFLGRRNLEIRNQFKLPPHLKIENFAEDDPMQPDNISAESNSKSRPTPTRRPSQAGYHDGEKRVLPTGPVTFHTHAANPSLTWEEDIDWLKKQCQPEMQVWVKGIATSEDAILAVHHGVDGIVVSNHGGRQLNGALATIDALPEIVQAVGGKIPIHVDGGIRHGTDVFKALALGADFVWIGRPVLWGLAYKGQEGVELCLKLFSDEIKLCMALAGVTKVKDINKEYLVKIARSGFVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7U0</accession>
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        <submittedName>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd"/>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
    <sequence length="424" mass="46798" checksum="DD93C1ED63CDBFC0" modified="2023-09-13" version="1">MAPASADGLNIIILGGGIAGLTTALALTKFAPQGQVPRIRIFEIRPEPGVIGGAVNLTPNALRMLDYLGAFQIIHERQYGRDIDYLEIFDAYSGKIAESDFRGPDGKGIGDPPYKALRITRGDALKAVMSALEQCENITMTCGKRTVKIDETADNVTIHFEDGDSATGDLLMGCDGIHSVTRLKHVEPERTATYTGVANAFGFAPVSKDFKTHFECTAINFAQRGMLLTSYHSPSNESIYVGGLMSVDDVGSRDGWKSVGADAEKTRQKLLDRFGDAKIPQLKPLIEAAQDFFLWPVYTLTKEGKWSTNRVMLLGDAAHAMPPQGESTGIVFEDTVLFARCLTRWIEKGKPNTMKEAFNAYETLRRGRIEDAFEESKNVVKTVSDAGWLGHKIKTFIVPWYLWFSRAGREKHFLEDVTKADIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8A7</accession>
    <name>A0A9Q8L8A7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid-like protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
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    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO12627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899651.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71980381"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Transmembrane protein 115"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
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        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377">
        <property type="entry name" value="PLACENTAL PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO12627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="381" mass="41208" checksum="F85C3F9CF6CD392E" modified="2023-09-13" version="1">MPLRINLPPLTRGLLLVVITLSLLNAVLRTNKWRNSLDSSPSAIAATNYLSSPQWAISYLVLIPTKSIRYPWTFLTGALVENNLVSMAISASVVYFGGKYLERAWGSREFAKAILCITMIPNIVTFFLYALWHGITGHSPEFPTPLNGLVALEAGFLVSLKQLVPEHTVSIFKGVIRMRIKHFPAVFVLANMLSGPLLGTDTAFWLSLLGFLTSWIYLRFFRISEISSTATGGEGSVMKGDASDTFAFVAFFPDLVHPVLAPICDGVYNTLVQLRLCTPFSDEAIEAGNKNAASRSEAGLPSIMNNRGGSGGGGRRAEAERRRALALRALDQRLSAAAANRTASPAPAVTTIQATLNPENSNADTGAGEIHNIAPAKEYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8J7</accession>
    <name>A0A9Q8L8J7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00922</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757127.1">
        <property type="nucleotide sequence ID" value="XM_047900070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8J7"/>
    <dbReference type="GeneID" id="71980800"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00922"/>
    <dbReference type="OMA" id="CFTSARY"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030596">
        <property type="term" value="F:alpha-L-rhamnosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF11">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase concanavalin-like" evidence="4">
        <location>
            <begin position="100"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="6">
        <location>
            <begin position="215"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="7">
        <location>
            <begin position="553"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="653" mass="73956" checksum="952C56EC75DA60D5" modified="2023-09-13" version="1">MDSRLQPAITVHLFDEDGTHQTIISGPDWKVRKSATTLANIYASGTHDRHANPLGWDTPAFDDSSWDAAKPVTGPRGELKYQHQPPVVLHEDLEPVAIKTLKPGVVTYDLGQNSSIMTKIAVEGAAGSEVIIRYAETVNNQGYVLMPDPLFKEFETHVYSKFTLAGTGEAEVWEPDFSFTSARYIQVEGVAVEPGQEFPVIRSAVGQHVSTGAKRLGTMTTDKEDVNQLINACYWSFVGNLFSYHTDCPQIEKFGWLEVTHLLAPITQYIRDIESMHSKILEDTLDAQESSWFIPNMAPDTRFMCGPMRNCITWNCAICFIPDILKRYYGSTHMIKQVYPAAVRYIEYMSTWERNGGLIMHGLGDWGRDIAFEANIETAVYIKCLQCLEIMATELKIEADIKRFHEWAEGIHKVYNDNLLVTDDTGHPQAYYTSLDEYPKGDCIVVAQAIALQFDLVPEQNISDVQNSFLEDVSDGRLRSGEIGLRYLFNTLDDLHRPDLVLQVARQEEHLSYMRFLRRGETTLLEFWQDECRSKCHDMLGTTYEWMYAVVLGVKPTEEAYKTWSIRPPYESEFGEVKGDVECPYGLIEVHYERKPDGKINLNLTVPLTTHANLLLPSACGAVSVDRHEKSSWTTEAGLKSIELRPGQYTIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8M9</accession>
    <name>A0A9Q8L8M9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757172.1">
        <property type="nucleotide sequence ID" value="XM_047900784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8M9"/>
    <dbReference type="GeneID" id="71981514"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01636"/>
    <dbReference type="OMA" id="FSFMPEF"/>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="7">
        <location>
            <begin position="40"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 C-terminal" evidence="6">
        <location>
            <begin position="543"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111309" checksum="C1F83F2D6B4F9889" modified="2023-09-13" version="1">MSDIQLYLLEVDKNHAEARKIAAQSATNFASKQIKLIDLITSLEEYINNKDDGGIRAKAVSYLADVLEQLPSKCLSNQERRLLCDFVLGRIEGDVEGIGASARALLALEERGKWDAETAQNVMRTFMDHTHPIRQFKLQTERYPVIRLIDRLLAKYRTAMKQIHGSDPRFLDSFISYFDGEKDPRNLMIIFSLMQVPMAEWDISANAQDMFDAVFNYFPITFKPPPDDPYGITAQDLKDRLKDCIAANSDFAPYAFPALLDKLDSTSMNTKRDVLQTVQACVIGYGANTVNLYSVTLWDALKFEIINVQEEDLAQEALKALAFIAAKFAGAEGPLQSYLRPIIKECNEHLEDAPTKQSQGAGRILHAVSQGGPEVADKIAKGILPVLFSLFQSSESITKRRGLLEVFNQIIQAYKEAQAAGIIGQAEALQAFADDALDALVRAVANAPKAEVSFRLTALSGLSQLASVRGALSEVQTARTVDAVDEIILRERVEGHGDISKDAIKALVELAHFVPDAVRQQAVPTFMVELPDVPGEQSTWQPVLVAFAQLSAEQQMFDTVVVRIKNKLDAARRQNASREYQHALLLALLYAFTFGSALQEDGVIRSKYYSEYAEPLITHVRGTSLSERDDSTVEIVGRIANIVLRQQTPHFQSTVYNQNLEWMSHATKSAPEAMESIRRLAPFSLYYYAAIRPDIVDPNDILSLLQAQASYLLSDDQDAAGSAIILRQLSLVINKFLEPRTMQESLTDSGLEVELLLSEEASSKKIAVAFAVVKALMIQGRSGALTTKYTQSLLRRLSTSDKAFARRFAGLLAPDDILTKENHCIVSALHKQKTFGQMVPAIVDSVRSADPATKSNYLIALSGILRWLPYSIIESSLASLVPALLQSLDLNETADQEVKYPTLTVFESLLMHDPNIAAEHTASLITRLLNSTSSPGNVAKVRAKALQCLSLVPKQLKPEAVIPYRRPVVKKLLGCLDDGKRDVRHEAVKCRTAWLALEEANEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9C2</accession>
    <name>A0A9Q8L9C2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757603.1">
        <property type="nucleotide sequence ID" value="XM_047902022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9C2"/>
    <dbReference type="GeneID" id="71982752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02874"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933:SF69">
        <property type="entry name" value="OS07G0513200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="2">
        <location>
            <begin position="323"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="645" mass="72667" checksum="24B573D78DE1E60D" modified="2023-09-13" version="1">MPYKIAPVDPLWQCLFPAWSQSTLTPAAQFLRRPKRPIFQCLSTPRPSPQSVRRYDRPTNLSRLDAASRHHDAVLQPMRRTKPVSYNKIVPPIARPSEDALPNLVNEPTSFLYGRLRAFAVDGKTTRCRQLAEYLVKERRERPSTQIYNAMILSNTSHDQGSAWRVSMLLDEMNEGGLQPDSGTCHAVLRVLAVHVDHLLRTDILDYMQKRWYQLSEEGQHDVVVGLLREGLFEQALQRLDNMRSNVRVDAWLWDMAVYVLCDAGEVEEAYRIMRVRHDSSEMNLSKSLWSHLLDKGSEARHHDATALVWNSQVNQGYITASSGVCLHVLATAAQAGDAVMATEVFAQLSERGTAFRPIHYELLISTYLSASPPDLSRAISILTIMPLEKTEPSIAETRPLFLYLRDKPALVKEAFATLRELHAQDRKIPIAALNLLIECYVEQRNLPEAMKIYKLIHTFVPISQGAQKSFANIETFNLLLKGCRTAEPPDEQQASFLVSELLALRVVPTALTYDRLILVFVSAGKAALQKAASIQDTAAAETERSKGKELLDWAFRHLADMQPLGWMPRFGTLEQLAMNLARASDERCWDVFQTSEDHGKDIEGFAEKGRYMRKNVEEAWNAAMDAKQDVQIDVGGYGGMAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9D0</accession>
    <name>A0A9Q8L9D0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type transcription factor afumD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03033</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757629.1">
        <property type="nucleotide sequence ID" value="XM_047902181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9D0"/>
    <dbReference type="GeneID" id="71982911"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03033"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO13263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="546" mass="60821" checksum="D5BEC2B9C35ABFD1" modified="2023-09-13" version="1">MAGQGTGPSRRSHTKSRKGCKTCKRRHIRCDETFPQCRNCTKHQVRCDYMETINTDAESQSSPEQSSLVFTPGTESRIDLWQQTGSFPYPSLQVFPPPQTHEYSKTELRLIHHLSTISNDLLLKSTSNLTIWTQKIPKFLSIASSYPYVMHALLSFSANHLAWSQSSNETRNLHIHHGTIALRGLHEAIGNFSHANVDAVLAASLLLLWQATDWRSWSSLRAGIQSVLSAMQSWKHESIFAEFISEEDVIGSPQSSMRPQPAVPTNERYMILSNTTQALQQLQRMLAGHEAESYWIGQLLQYLQRLQSSQPASSPDEQFSHLYLLRKWLFWVPVLLLQRQGGQGPAMLTLAHFYATALALEPLYPDLGSAFCARIALVPLETIISVTEAMQSQRAMDQQSMEIASSMQFPQQTALGFRNRMMMETQHGRMKQGQAMMGVSHDTFSYTSIGNLSPAFAPSPLHSTAAQQTQPPTSHASYLEVPATQAGFSYGTQSWGAMPSPGFPPQAYAAQDEQLYGYSLGGFRGDGTPSNDPGAGPSNTHYQQQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9T9</accession>
    <name>A0A9Q8L9T9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757801.1">
        <property type="nucleotide sequence ID" value="XM_047902911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9T9"/>
    <dbReference type="GeneID" id="71983641"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03763"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040204522" evidence="1">
        <location>
            <begin position="21"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO13435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="316" mass="34277" checksum="46017E328EBFD116" modified="2023-09-13" version="1">MLPAQIYLLALASIAKCSMAQGVPTFGSIAESVCKYAGPLGDVLGVIDFIADKIPDASDVGGTVVQIGTSGERHDGEDFVVWTFDSMNKVLGSSSVDPGMIKAAGYRDIQVHQHMGDQAQGQYVDIIAGDDEICISYILATYPSGPSGPRAWLGDVGAMCGQAWEHSSTTYSAAANETHYGKCVWMDTDHGDDIDYQPQAITNRQMKINMNAYGGDALKEENRNLEYICGATIFTWDIAIPIDVPTPKGPVPLSSLDSRDAGLRKRYDYDYKQPGTPRQRSQNSAERLVVKFTTAAVGGYALQFSYVQGLGFRFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAA8</accession>
    <name>A0A9Q8LAA8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758139.1">
        <property type="nucleotide sequence ID" value="XM_047902306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAA8"/>
    <dbReference type="GeneID" id="71983036"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03158"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="30533" checksum="02CDF822932D37CD" modified="2023-09-13" version="1">MTSSSEPKGDNMLSTIPTTHQTYLRWATRADIPTIARILRDNLLDFEFHDHFCPKRKENPEEFYLFALGRVRMFFVKPCIRFMVAEKLELSVSGHQRTKIVGFSTWDAQGKDNPIAKEWRRQDSGWLQAIERKLIDLELANYRYLQNTIFEYDAFQRAWRLLHESYAHIESLESNLHLQFLMVDPAWHGRHGIGHKLLQWGLDVADAVGLPVVIESSLMGYPFYLKHGCKLLTHVRIDVVPEKAYDMPILVYEPEGKEGVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB00</accession>
    <name>A0A9Q8LB00_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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        <property type="entry name" value="BLR7373 PROTEIN"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF3">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="20188" checksum="7C89658EDCCB80F4" modified="2023-09-13" version="1">MAAKLTPLKDLKVLRHQIPAHDLTPNTSLARKPLLIYKSAFLTSTSASQTESHLSTVGVVTPQWRYTMYSTTRFHSTSRELLAVSRGKAKLCFGHEENEGRVKTVVERGDVIVVPAGVGHRLLEDLTEGGGGFEMDESYPRGCNWDMCYGKKGEESKVEKIKGLPWFERDPVDGDEGPVLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB43</accession>
    <name>A0A9Q8LB43_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03790</name>
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    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
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    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
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        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
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        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
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    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
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    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
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        <location>
            <begin position="583"/>
            <end position="829"/>
        </location>
    </feature>
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        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
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            <end position="630"/>
        </location>
    </feature>
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            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
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            <begin position="765"/>
            <end position="786"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB89</accession>
    <name>A0A9Q8LB89_PASFU</name>
    <protein>
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            <fullName evidence="5">Autophagy protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_02791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
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    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the ATG16 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="VQACSQM"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATG16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 16" evidence="4">
        <location>
            <begin position="7"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="37"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO14185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="22659" checksum="5756285C125B4B0F" modified="2023-09-13" version="1">MSDWIEQYSAALDARDAREQAHKPYIDAYTKLADRTASIATTNTQNTTHANPSSPRAPPSTTDRKRPTTTPSDPTSHLNTLRTDLATTQKARSNLQTRVSDLTATLSALQTTQKQSTSQIAQHTAQKAAAERKLRDREEEIRGKARLVQTAQDEMVALQLQLNMAEQRSERLEAENKELVERWMKRMGEEAERVNRGSGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBJ0</accession>
    <name>A0A9Q8LBJ0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758754.1">
        <property type="nucleotide sequence ID" value="XM_047901553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBJ0"/>
    <dbReference type="GeneID" id="71982283"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02405"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="178" mass="19121" checksum="DBE0123234AF5D26" modified="2023-09-13" version="1">MLTVHPPTQAFRVQMNFSPNPYSPRVTVSPPRRLQSQCVLVADGPESEATIIRLEGRKEIGRAMALGAASVGQDGKQRRPRGGRRRGKEDAGMAVGEMEVSLGEELAEGFEPGWVREGMEEDGEVSGGGRKGGGAGQTGRRAEHEAEQGAEQGVEEEEEEEEVVFKGCGSMALVAWQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBU5</accession>
    <name>A0A9Q8LBU5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_02371</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758982.1">
        <property type="nucleotide sequence ID" value="XM_047901519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBU5"/>
    <dbReference type="GeneID" id="71982249"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02371"/>
    <dbReference type="OMA" id="QAMAYGV"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000033">
        <property type="entry name" value="NUAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="15">
        <location>
            <begin position="114"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="14">
        <location>
            <begin position="253"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="729"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UJO14616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="752" mass="81927" checksum="82E00306A8C8DBC5" modified="2023-09-13" version="1">MARQALLRSLARSPATATLNATRTARTFATSTRRHAEVELTVDGKKVSIEAGSALIQACEKAGATIPRYCYHEKLMIAGNCRMCLVEVERAPKPVASCAWPVQPGMVVKTNSPLTHKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMRYGSDRGRFHELDGKRAVEDKNIGPLVKTSMNRCIHCTRCVRFANDVAGAPELGSTGRGNDIQIGTYLETALDTELSGNVIDLCPVGALTSKPYAFRARPWELSHTETIDVHNGLGSNIRMDGRGLQVMRILPRLNDDVNEEWIDDKTRFACDGLSTQRLTTPLIRRDNQFQPATWENVLVEISEKFKQLAPKGDEVKFVAGELVETELLVAAKDLANRLGSENLALDHPQGSAPLAHGIDVRSNFAFNSKIYGVEQADAILLVGTNPRWEAAVLNARIRKQWLRSDLEVGLVGQDFESTFDYENLGASAKDLKTALGGAWGEKLKSAKNPMIIVGSGAVEHPDAKAIYETVGSFVEKNKANFVTDEWNGYNVLQRAASRAGAFEVGFTVASPETAKTTPKVIWLLGADEIEAADIPKDAFVIYQGHHGDRGAALADVILPGASYAEKGATWVNTEGRVQISRAASSLYGAARDDWKIVRAVSEALGTPLPYDDVEQLRDRMEEISPALRRYDIVEPTSKELQALSKVQLIDQNKGSQASGQPLRQVIENFFFTNSISRSSPTMARCSAAKAAKNPETNFMAPGEPIPQVAYGPPQIAGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDF3</accession>
    <name>A0A9Q8LDF3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LDF3"/>
    <dbReference type="GeneID" id="71988221"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08343"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="145" mass="16279" checksum="E92650F17A9F1EBC" modified="2023-09-13" version="1">MEPPSANDETPTIANAIAVAFRFGRDDGLETGIVEGKIFQAAKESSHMTLQIVNLAQQKEQLSADLDSTIEQFRACVDAQTWQQLRERLYQLNDEVTRVLAKMMFVKEQLERFEAEAGVLRDEVDNLRSDQQTQNTSDASNTEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDP5</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="71987789"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="344" mass="38536" checksum="10A3C289E10FAC91" modified="2023-09-13" version="1">MDELETDQLSTEREKTAFRISCFCEEISLCARRPAREYALVPSAWYCTRQLPQRLHFISSNFTFPYVADTRSIIGVLDTPSSQSYSGAPNMTDEREAPSHPHGTYPLDKGLPQGVPDELPNQAQQLPCTRQTQPFFELPAEIRNAIYELAIPSKHRGDSLVITTPNWDELMVSAEQPAITRVSRQARSESLPMFYGTNDFKAYIQYYDFKTLVKWADCVTSVPKPPKLRVQVYLLDKMSCNVGLRDVALAWRDIKHETIHLTIASAFPNAAPGQSQCTAVAGATKVAEERKVAGDRRDETTIRHLLMSGVLGVCSCPVLAGRHIITTCSREMMGQNAIPRSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LDZ7</accession>
    <name>A0A9Q8LDZ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Fulvia</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="71988658"/>
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    </dbReference>
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        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54526" checksum="E846CB25D5235B86" modified="2023-09-13" version="1">MADIYGTTTHNLIWLGEEEPYTQSALSAICAIGEEIREETEDFALLRDMLYDENTYFRYLDSHLKAQYDTSALVSFLYLEWFSRLWVVQEAALSSRNTCCVGALNIGLDEILRVVGWLRHKWHHIADDIKDPVGSIFPLFNWADRQHGLFGSGLRSPEAMDLLIDLRAFHAFDRRDHVFAILGLLQKHTGSETPVALAADYNASLATVLHPATKYIVQEREHLEVLRFVTHRAVENNEDDIASWAPSQHVAWDGAVDTMGFQGLWHNASAGRKFVTQQLNDEPSILRTTGIAVDSVQNLGTVWRLASRRDYSIVQLIAEADALVAGTSAGVANRNAFAAMVLCAGTTESLTNYQEAEAGAACLAYTSLKEQWLALPDDELEPWAQYLSRNDKSATSFAQALANASHNRMVFKTTSRYVGLGPQTTRKDDIVAILYGSRWPVVLREFEQYPGDYEFVGTCYMYGIMNGEAVHEHEASGKEVETFRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LF41</accession>
    <name>A0A9Q8LF41_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_04464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LF41"/>
    <dbReference type="GeneID" id="71984342"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04464"/>
    <dbReference type="OMA" id="PSEYEFA"/>
    <dbReference type="OrthoDB" id="3935682at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040212672" evidence="2">
        <location>
            <begin position="18"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="221" mass="21844" checksum="20A951B35FB89156" modified="2023-09-13" version="1">MLAQTLSVAALVLSVSAQSISSESISSASSASGGSGTAARATTTSADGEVQTTITGLIGSLTSGFAASIVNANPCETTLAMQCTGDSYACSIASDVEIMVTQNPSEYEFAYATSTLGGQITLSQSCSLDGPSGSASQMICSASYRVSAGGQATGSTTVETLTNSDDFNYGQIPITAGAEKLPSAGTSCTVTQEQGAAAPTCVSEVYKIIVPVAAGLVGALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGI9</accession>
    <name>A0A9Q8LGI9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
            <shortName evidence="6">RNA polymerase III subunit C6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_03927</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO17006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761372.1">
        <property type="nucleotide sequence ID" value="XM_047903075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGI9"/>
    <dbReference type="GeneID" id="71983805"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03927"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="389" mass="43687" checksum="2B0508684DA419D2" modified="2023-09-13" version="1">MSSEKSDIADRADQLYTVAAANAIQEANVGGATVNAHSRCFFADELVELGGLDSNNAVMPLIQYLTKNNLFRTLRQSGGKLGWSVRPRDAARQIKNLDRDEKAVYEEIEAAHTHGIWTKEIKRKTNIGDNSMKKAITKLETTNLIKSITSIKSRYQKTYILAHLTPSEDVTGNSFYDAGDLDESFRDELMNLIIFWVRQHSWKEPSRKHKVKREPTSPVLGAEDKEDGSKKRKRTADIEELGSRPVKHRSARFDPETDHFTQVMYKAGTHNYPTAEGIHAFLSTSEVILPTKRKSLTVQEIQGCIDVLCWDEKLEKVPTRDGEWGYRTVRGISHKPPGAAYGDFDDTSGTALTQAPCGKCPVFDICHEGGSVNPQECVYFTQWLDIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <name type="synonym">Cladosporium fulvum</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="111"/>
            <end position="132"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="19"/>
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            <end position="48"/>
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    </feature>
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        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="185" mass="20765" checksum="7684976DCC9E52DB" modified="2023-09-13" version="1">MSYQQYGSSSYTGQQYGYYPDEQQYYTEQRTPPSRSQQYYDYTPSSAPRTIRPTTTGYPSPPSSPYTSTSNPYYYYSSSPSSAYSTSPTSPGPSHSQPSQPRPQPPVEYHCLICTHTCARKADLERHYSAMHCRDSSALVDCQWAGCHRVGQAGFGRKDKMVEHMRDVHKADIPKRGGGTGGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHY1</accession>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        </subcellularLocation>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="Spp1/CFP1"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
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    </dbReference>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO17718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="24746" checksum="B747C5A578CF996D" modified="2023-09-13" version="1">MTARTVAIKSRQAAAQDALLDDTSHDPTPVPRSGFRIRLSKPPPRVDSPPADDDSVSEDDSIQDATESVDHRLEKDHWAEGLVCFSKYLASSKARASRQPEGYNDSLIACDGPCEEWYHDTCVNVTFDEAESIETFICPICVGNGYGRTIWKKAATSTAQDNGTGANENEEIALAGFPRVIPVQRKREHRALSLKVVGIVRAEAKRKVRWQEGRGPRGLGKVGISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIH8</accession>
    <name>A0A9Q8LIH8_PASFU</name>
    <protein>
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    <organism evidence="2 3">
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        <name type="common">Tomato leaf mold</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIH8"/>
    <dbReference type="GeneID" id="71985929"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06051"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="90" mass="10047" checksum="99E4B6577A0AD526" modified="2023-09-13" version="1">MVALQPTSLHPGSGGFDAAPRSCPASHQKIVESAAGVQVYGRPLKTFVQQLDIEIAAADLFRYFVLSIIRKALLYLKLRNYIFLEMCIMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ48</accession>
    <name>A0A9Q8LJ48_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zygote-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
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        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="8141" checksum="B6098FD83363394D" modified="2023-09-13" version="1">MPSRTFTLLATLTTLVPLANAGPAAYGICQTGCAGVVMACYGAAGFTWGATLGATAPASVLACNSAYGACQAACASTLLVPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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        </source>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17818" checksum="880A0CE903E2DAC9" modified="2023-09-13" version="1">MQDQEAPYPNITPIPPSHSRHPSQRRLRSLTVQLPQWDEKSWQPSSETDVEKSALSPDAKPREHHMEAMVKTTSEVKFPRRAYAPNRTQEPRTPKAMPKAGVMGYYFDGQNYVGLQTNGRTPPTGSVTPVLFDIAEGDVHSQLQGTPDLTLERNVRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="17862" checksum="D8591C7B34736730" modified="2023-09-13" version="1">MDYICVVPRARLMTTAKVLRSVIANKPLVTADWLSASKKADAVLDIGDYIHEDFIATDRSSLFAGRILFFTSAPKTSFGADWDEIVQFAKKVGATSVESGSATTGHDITPKERVLLLGVDKADKDVKALIWDHERVVYMKTMLARTILAAAFAPEASRITLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3G3</accession>
    <name>A0A9Q8P3G3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein JIP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">WD repeat-containing protein jip5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02100</name>
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    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
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    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
        </source>
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        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
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    <dbReference type="OMA" id="QAIHPTE"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
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    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="432" mass="45987" checksum="44C14F4E4CB86BBF" modified="2023-09-13" version="1">MFDTICTLPLESDLFAQAVHPTEALVTVGLSSGHAAQLKLPPVEDDAAAGHVKTKGRRGSNGTDVVDTTWRTKRHKGSCRCLAYSTDGRQLYSAGTDGIVKAADSETGRVTGKIAIPIDPSTSRDGVDAPTVVHALSPQTLLLSTDSGALHLCDLRDPAPSIPLSDSKTAFASSRPSQVYHPHADYISSLCPIPPSAASTSGYSKQWLTTGSTTLALTDLRRGVLAKSEDQEELLLSCLYLTGLPAKKSSGSTGEKAVVGAGDGVITLWEKGQWDDQDERITVSREKETLDCMTHIPDGIGAFGKKVAVGMGDGQIRFVHIGPNKVVGEVQHDEVEGVVALSFDVGGRMISGGGQTIKVWQESIEAEEAEEDDGDDDGAALKRSAKDSDDSEQEDDDDDSSDDERSRRHNKKKKRGKGQPVTESNFNFAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3V5</accession>
    <name>A0A9Q8P3V5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_00173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756786.1">
        <property type="nucleotide sequence ID" value="XM_047899321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3V5"/>
    <dbReference type="GeneID" id="71980051"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00173"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="78" mass="8631" checksum="96F983F1D8AC9564" modified="2023-09-13" version="1">MPGISEGLKSNALPAPVLFVAGIMGLLLIERGIRSRATGRHTSAKIEGIKDEDDYDTRRNKRQDLHQRREKTSRAGSS</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="EmrE-like"/>
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        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
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        <property type="entry name" value="UCP036436"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040110091" description="Integral membrane protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="444"/>
        </location>
    </feature>
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        <location>
            <begin position="49"/>
            <end position="71"/>
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    </feature>
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            <end position="170"/>
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            <end position="193"/>
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            <end position="221"/>
        </location>
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            <begin position="266"/>
            <end position="285"/>
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            <end position="324"/>
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        <location>
            <begin position="344"/>
            <end position="368"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO13005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="48964" checksum="FDD8B0B5FA9A4571" modified="2023-09-13" version="1">MTSRAMIPVLVAFMLLTGVCNTLLTKYQDMQCVADCDTDRPKKFEQPVIQTLQMFVGEAGCWLVVVLSWLVKRVLTSDVVPIQDTRYVPVASEEAGEELESDENELHHDLSSSQTLVDPTNIVAAPKLDPELLHKERQPLTGWKVTMLALPAICDICGTTLMNVGLLFVAASIYQMTRGALVLFVGLFSVIFLRRHLGAWKWASLFIVVLGVAVVGLAGVLDQKHGAPTLPGDTRPDDKTDLLTHAGLALRRGVTALEEHTAAETVLGFFLIATAQIFTAAQFVLEESIMERYSMDPIRVVGWEGVFGFLVTLAGMGVLHAAIGQTEAGKGGYFDAREGFYEMFHYRSIGITSLLIMVSIGGFNFFGLSVTRVISATARSTIDTCRTLFIWLVSLGLGWETFKWLQVVGFILLVYGTAVFNEVVRPPTIAFLRRQKRVALQEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4L9</accession>
    <name>A0A9Q8P4L9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">CLAFUR5_00757</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4L9"/>
    <dbReference type="GeneID" id="71980635"/>
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    <dbReference type="OMA" id="ENEWTTV"/>
    <dbReference type="OrthoDB" id="4207724at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="426"/>
        </location>
    </feature>
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        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
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        <location>
            <begin position="204"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="426" mass="45963" checksum="245B74B96F0E6F52" modified="2023-09-13" version="1">MEDPTQTLQNWLIFASIIGGVAWYYWPKGKTVPKPAQAAKEVKKDVKKAARKLEKPKTLDTGVKSTEQPQSYADAAKEDAAEHSNKKRKTAAQQGYAQAASNAVVERKDAEEDIDMSTRQFAANMQKARQGIQVKSTNNKETRVKTVKAKSPVQAPTISSGSSQQDADEEWSSASVQAQAGGVEDMLEPAAPGPSALRITASEKPTKDKVNKQSKKQEVETKKQRQNRKKTDDARLAREEADREQKANMEKQRRIARESRGEPAKNGVPISSAPVTNPWKEQNAAREAQISAVGNTGAPAQLLDTFETESNSSSHQEPSTAATSVTDATPEVATVVGSDTASDTTPRYSEQAVAGKDEYAKAITESEQDSGWNEVKVSKKSKKSNSNSNTKGDATPVAAPVANGKQTKGTANSRRTMFSALGDNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4T9</accession>
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        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="9" type="ORF">CLAFUR5_03070</name>
    </gene>
    <organism evidence="9 10">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO13186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757552.1">
        <property type="nucleotide sequence ID" value="XM_047902218.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71982948"/>
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    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="483" mass="54069" checksum="2A0E2B2251CD5DAF" modified="2023-09-13" version="1">MLHHLCCHADADQRHLSCRLHFSMDDRAPNKRQKRRAVACETCNKQKIKCSGELPCGKCETAKKSDTCRYPVRDRNVTAPESYLEAVESELSILKATSSANPQAASVEPSAQQGTTNHSTDPDVANPLLDIQNGLFDRMIASKLGYPLSISDEDIDVEMPSMDTLYDQEQTEFSDPVPLRAHVGLARITGCILSDIDSIPKHQKETFPRRVYRVHNDLRRWDAELPESLRLKAEMPPRNLFTLHMHYHLCIIQTTRPILLYLFKTKFRPNIGSEPVQQPFSPLTLALADACVQSARTTNQLLSKLFIEGNLAVFDYFDAHYLFSSTLILIISACMNPATSTSEAVATALSLLKAMADNGNIFARDYLGRLEHIRRQVSNVRSWEEARQDHSFNALPQVDVPIDPAQSLGGVGTTAHRHHAAAETSVESLLSGDNFLHDDPLGNPFIESFLAEKAFSWPDGPSPDQDIFRQFAHELEDEFVFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4Y4</accession>
    <name>A0A9Q8P4Y4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endoglucanase E1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757687.1">
        <property type="nucleotide sequence ID" value="XM_047902138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4Y4"/>
    <dbReference type="GeneID" id="71982868"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02990"/>
    <dbReference type="OMA" id="SAHDYAT"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040145414" evidence="5">
        <location>
            <begin position="31"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="66"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="49852" checksum="5FFCD12C87DBD7F1" modified="2023-09-13" version="1">MIRRTLLLSATILAITFLFFSLQSFPSGQAQFAYLPRQRSRYQWNTTDDMLLFQPPLRTAGRHIIDANGERVKLASINWYGASVIFFVPGGLDFRHRDEIAATIRQMGFNSVRFPYSDQMVIENPIVPPEVISANLDLLDNYDLGHNESLSESDEPQGPRALDVYFACVKAMTDIGLAVIPNDHITNAHWCDGMNLCDSSWKNDHLGPFCKIKQTTDSWIDNWKIIMRPLADNPLVIGADLRNEPRGFWGTMTWNMWATAAEKASEALLSIQPNWLMFVEGISSANDCGGARSRPIKLSVADRVVYSSHVYSWSGWSTLVPYGKRPYPSFPTDMDKNWAFLIRGNIAPVWVGESGAPHHAGDQDRNYWDHLMKFLDEIDADYGYWALNPRKPGGYDNETYGLLRDDWETPVDDYRLADLQKLMKPRKERTVKFNVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P593</accession>
    <name>A0A9Q8P593_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar transporter chaperone 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_03352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758017.1">
        <property type="nucleotide sequence ID" value="XM_047902500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P593"/>
    <dbReference type="GeneID" id="71983230"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03352"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000002">
        <property type="entry name" value="Vacuolar transporter chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="725"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="100"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="594"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="599"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="628"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="845" mass="96268" checksum="2E7BE3FC4DCC0CF6" modified="2023-09-13" version="1">MRYGRTLELSRYKPWANNYIDYAKLKKLLREDDSAPSSPTPETTPSKNEKWTDEDESRFVHELVNVQLEKVHEFHRDTYEKLRDRTAKCEAKLDTVAVAEAGEKNNNDNNNNNNNNNNNNNNNNEDGQTDGANSSKGEGKDSPSSNGNGKKPVPSEAERKTILKEVLSELDHITKETNELEKYSRINYAGFLKACKKHDRKRGGSYRVRPLLQVRLSALPFNREDYGPLLFRLSAMYSFVRTRLDESGDQPKALEDQQGKEEYTSHKFWVHPENLLEVKTLILRHLPVLVYNPQTSKVAEGNQPDPSITSIYFDNPAFELYSNKVDKNAGSSLRLRWYGHLNAKPQIWVEKKTVQEDNKSSEDRFTTKDKYVQRYTNNEYHMEKQIQKLEDRAGAESNEAKSFKSSVEEIQAFIKRYELQPVVRANYTRTAFQVPGDDRVRISLDTDLAFIREDAIDSDRPCRDPKTWHRTDIDNNELEYPFSSIRKGEISRFPFAVLEIKLRSTPGKRSAEWIQDLMNSHLVKTSPKFSKFVHGVAQLFEDYVNTFPFWLSEMETDIRRDPQQAFEEEQAKRQKERDDEFAVGTLLRTSSMFSPAQKSGGVLSPVGSPSVPSTSIQRSPASQRKDATQAPRQQQATAEPTQMQDTAGEIDDDDTGTHTHNTELNRTPSGLKSLFPTFSTSKYGTFKRGNRTKLPPGVVEPKNWIKDQGTNKVEGKVWLANQRTFIKWQHVSILLASLSLGLFNAAGPNNTVGKVLGIVYTSIAVFAAAWGYFTYMWRANLIQRRSGKDFDAVAGPVIVCIGLIVALILNFAFKHKAVMEERRNQDAHLGVGINQTQFLGMHSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5K8</accession>
    <name>A0A9Q8P5K8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cercosporin MFS transporter CTB4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cercosporin toxin biosynthesis cluster protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03045</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin. The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules. These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids. Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758377.1">
        <property type="nucleotide sequence ID" value="XM_047902193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5K8"/>
    <dbReference type="GeneID" id="71982923"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03045"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF49">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="176"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO14011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="67146" checksum="D46B1AA2A014B38C" modified="2023-09-13" version="1">MRPALRSELCCHVAEASTSFRTLCSSATMCRVCSLLAKATFKRAKTSPTSAEPLASHSVDSNADNRLAIGYNLLHACHVSLARSLRWQAITTVMESGRTSASGMATPGEKRDEEQARSDVDLASSQEKDLEKNESPVSAEDPTAPPEVREESFKARFDDNDPANPRNFSNTYKAFITLQLGFMALTGSVGSSIIAPAEPVMSSYLGVSQETTVLVVALYVLGFAFGPCAWAPISEVYGRKWSMLPAMFTLGLFSIGSAVSKNAPSLFITRFFGGVFGSAPISNVSAALGDVYEPKARGIAITFYAVMVVGGPILGPVMGSAITVNQSLGWRWTEYIQAIFTFTMVAVAFFFLPEVYHPVLLKRKAKQLRNETGDTRYWHPHEAERIKPSNILTKYFSRPLRMLTTEPMVTCIAIYASFVYGILYLTLEVFPIVFREMRGYSPVVSTLPFLGLFVGVLCAVGINLGNQSHYARAMARNHGRAVPEARLPPMLVGGVLFTTGLFWFGWTADPNYHSAFPVVAAGFIGAGFNTIFQQCINYLVDSYGRYAASAVSANTFLRSIFACGLPLAAGPMFRNMGIGPAASVLGAVSCLGLPVPFIFMKYGLKLRKLSKFAPVPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5T2</accession>
    <name>A0A9Q8P5T2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758645.1">
        <property type="nucleotide sequence ID" value="XM_047902679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5T2"/>
    <dbReference type="GeneID" id="71983409"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03531"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="282" mass="31973" checksum="EDBB9349E2212030" modified="2023-09-13" version="1">MLVAHHDLQAKKLPKSKTPVNADKYTTRMLLKRVHTTTDVADAKDFTTAIVKLYKGNGLYPLSAIKKLATFPDTFDLAVDQLFEAFSKASSPANYMDHMKYWRSIRKPQGAFGRYIKNFDQALAWMICSHWLHLLKEGRDLDWLPMYLDDRIRKVWSALLGASSPPFKYRDVLTKKDPSIFSTALGLLKFCQTRCAVGIKVMRVAGHRLPPELVNAIKEMAIGRGEFLNMVKLMLNAGDQGCARMLVFPPGVPPRGFSRMLRTPRWADPLKEFLELCPTVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P626</accession>
    <name>A0A9Q8P626_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758974.1">
        <property type="nucleotide sequence ID" value="XM_047901635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P626"/>
    <dbReference type="GeneID" id="71982365"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02487"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO14608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="143" mass="17073" checksum="2FB8E11F274F4CFB" modified="2023-09-13" version="1">MALAKLNDDDYNHYKTIHFCLFVERQSANSNSELAYCHRESMRMPEIATKRFESVQHYHLFRKAEVISNYGYEDDGDSRNIPVVSPLSMDVRRNMDVRRNMDVRRNKSAWFWQEMTSVTLTGRGKQEWESTDKNYIMHITRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6S1</accession>
    <name>A0A9Q8P6S1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759694.1">
        <property type="nucleotide sequence ID" value="XM_047907180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6S1"/>
    <dbReference type="GeneID" id="71987910"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08032"/>
    <dbReference type="OMA" id="LMCATEP"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF154">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_2G04560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33427" checksum="6A064F3CF9DC27C7" modified="2023-09-13" version="1">MSSASFNPSKDIPSLTGKVIFITGGTAGLGSGSIRELAKHDPSHIYFSGRNEKNANSLIERVRKDSPTTNLTFIPCDISSLASVAQASQRLTSLTSRLDILMLNAGIMATAAATSQEGYEIQMATNHLGHALLVKLLLPTLLSTASLGADVRVINMSSIAYKQAPSPGISFPTLKSAQPKLGGAVVPGHRWARYGQSKLAQLLYSQELAKHHPEITSVAVHPGYIMTGLFDGLPMMTALPVLLVSLGRRTPVERGHYNQCWAATCEKGKLRNGGYYEPIGVLTKPATKQANDEKLAGELWRWTEEQLEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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    </organism>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12751" checksum="1B8BE4906DC51DAD" modified="2023-09-13" version="1">MGELLFLTLCWAHHRRPGGYRPLLRAPEIDLLVFRGMYPTPGRPGSPLLVAPPQLHGKERMKQIKRHAQARVKQWREKALRKAQTAVDAVREQGGEAALALEIYFSSRRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7C7</accession>
    <name>A0A9Q8P7C7_PASFU</name>
    <protein>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="UJO16005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="686" mass="78571" checksum="052403F433E04990" modified="2023-09-13" version="1">MTALNAAPVAIFRLPAELWDLVQKNLPSIKDRVNASLAFRDTRGQTRSLVEKWVPEWSKMIEEADIKANILNNENLVLTYAEALNIAIKAWTPMRIKPSMASSIAQHNPALRQYTYNQLRRHQRRHGISKDGLNKDQREDQARLKEELLFPTARSAARERACAVFLFNNVRREAIATQVCQARLCRAYGGDRRQQHHDIKFCDVHLQEHIYSGTVSFKQLADFCIRIIPNDTEPGGVLSWTVPFLSTDSRNAFESLSFAEADVITLGIYGLRWVELQRRRKAWSRELRERKGKEYSACIEALRVLRDWTYAGMDRTSGERTISGEMLADDFPWDLAPAFRAATGEDLRSMPKIVELLRHLGSQYQASPAATVDEYRLESAYRITKKEQLWANEAARKWIKPKLDSLGWIPQPRLCNQFQIVADKSFEPLVFTRKFNTPTERSYCTTEEAEELCNLIHGQGLDTLLSNIDYHTRRRNLAIYLHLQVGLEVLETQTTPGIMELSHDLSTAVRGRGEGFDTSSFAELPPFKPSTIGRKWILETAQDPVNTYVKWLEEMIDAEGGQLFLARTPDEVDQKHLQPFVQDFWKHSTPTISEDDVETWLGGKVAELVLDETSSGRYSIWEKHKIDEALSGPWREILECVECDIFHVKKGFVDGFAAHKSEKILGTKAKPFCCGRVLWFDESQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7G5</accession>
    <name>A0A9Q8P7G5_PASFU</name>
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    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <strain evidence="1">Race5_Kim</strain>
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    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF2">
        <property type="entry name" value="THREONYL AND ALANYL TRNA SYNTHETASE SECOND ADDITIONAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="95" mass="10558" checksum="AA29D5C8C91A2F7B" modified="2023-09-13" version="1">MDSITKPTHLTFQHDGSLTRLETNVVAVVSLTQLDEQDRALFKQDNDEKWQIVLTEATIFHPQGGGQPSDTGLITSSSFESSIFNVIVARTSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7P1</accession>
    <name>A0A9Q8P7P1_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </dbReference>
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    <dbReference type="GeneID" id="71985044"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="171" mass="18521" checksum="2309545EC9EF6E29" modified="2023-09-13" version="1">MSGTPSDSKLGPLLDENTMQNLSYAQKCHIGRTKNTGVADYGRYSDDLRYERDAKKFGELPGEPPQPQPPMGFALNRAKALEKGPINNAYTNLNIKPRATGESAQGDVTANVGALMPVQTNTSSTNKDGKKGKKKSFLEYLFSDDEGGPAQIRPKDSKGKDKAKKVTKTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7P6</accession>
    <name>A0A9Q8P7P6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="7 10">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7P6"/>
    <dbReference type="GeneID" id="71983849"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03971"/>
    <dbReference type="OMA" id="SATWILK"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
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        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
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        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="11">
        <location>
            <begin position="56"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
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    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="86"/>
        </location>
    </feature>
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        <location>
            <begin position="77"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO16380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="34577" checksum="CABE1A371C3D7BD0" modified="2023-09-13" version="1">MVVASTSVLSLTVASTLLQAGIAAVIISSFLVDAAAVAERNSAVSEDKNDPTSGSSGSCPQIWSQVASQLKSDFSGCNDFARSAIRFAFHDAAGYSSSNSQYAPASGGADGSLLLNDDEISRNTEAPMKENYRDPYLLPFYQKYKGQGVGAADLVQFAGAVGIKSCRGGPTVRAVVGRKDSNQAAPQGTLPAAFGQGSDYDSLIQLWGQKGISPRELAALMGARTVSISFTEDANGIPPGSPQDSDPTVWDNHYYTQTQSQKEPWGVHSFASDVNLSNATTECGQAFTDFGKDSATWILKFSAAMQKLSLLGIDSETVSGFTDCTSLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P829</accession>
    <name>A0A9Q8P829_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P829"/>
    <dbReference type="GeneID" id="71984120"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04242"/>
    <dbReference type="OMA" id="NKHGHHP"/>
    <dbReference type="OrthoDB" id="661148at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="Nbr1_FW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
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        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="5">
        <location>
            <begin position="198"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="5">
        <location>
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            <end position="345"/>
        </location>
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            <end position="416"/>
        </location>
    </feature>
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            <begin position="432"/>
            <end position="485"/>
        </location>
    </feature>
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            <begin position="788"/>
            <end position="818"/>
        </location>
    </feature>
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        <location>
            <begin position="894"/>
            <end position="950"/>
        </location>
    </feature>
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        <location>
            <begin position="795"/>
            <end position="812"/>
        </location>
    </feature>
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        <location>
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            <end position="920"/>
        </location>
    </feature>
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        <location>
            <begin position="931"/>
            <end position="947"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="994" mass="110046" checksum="E5CC575F66A96772" modified="2023-09-13" version="1">MAAPHTTGGSPSPDTLITIKISVNDQLKKLKLPLRDLGAHTLPRKLRSVLDIKPEQTVLLERYSDSAGGYITLDESNPQVFKTLIRAAKAKLKLRLKATVSPVSIPVVEEEETLMPKMPEMNPIRDSTALDQRSIGSGIFQFKEARASQQTLVNDEAPVPRPFTADRSSILNGLALPSQQSLAFRPREPSALSAVHPHAWSVYCNECDKAMANEHFHCSICDGGDYDLCEECVSGGKLCPGEGHWLVKRYIQNGKVISSTTERVQPRKVNIVPAFIKQEPVEKDIPGAFTEETKTLAEDTRTPTRTCNSCVIVLPEREFVTCTTCDDFDLCIKCHTSDKHGHHPAHGFEPSTAETILPLAAETKLAPGRNVRHNAICDGCDKKIYGIRHKCLNCPDWDYCSDCVKDARHSHPRHRFAALYEPIADQGQSAVRHFGIYCDGPLCSGKSDQSYIAGVRYKCTICHDTDFCAGCEALPGNHHNRTHPLIKLKTPVRNVNVSTENEDLRGNVRVMGDRRASPVSSTGTETSPIPQANAATQVQTVADFQPTEVKKETMPISIPVKTFEQKGLVPEPAAVPSTLLNAHFVRDSIPDGMAVDPEARFTQIWTLKNPGPYVWPAGCSVRYVGGDNMLNVDNSHPASVTAIADATESNVVGRDVQIGEEVAFKVVLKAPVREGKSISYWRLKAADGTPFGHRLWCDIEVKKAEQKTPSPSASIFQEQQIAMQRMRIQQMQMLRVQQQAAREQTLRFNAMAAQQAQNIPAEQPPAYDSMGLSARLAAMREQQKQRREQMVAQRDQLQAQGNTYCGQRSAEFSNEKERREALKQRVAHIKANIIKTREEREKMTEDFQQLKMAAAEKKSMEESEKVQNIIEQVAKQADEEEKTEQLEGSQMVFPKLEKESPSSSTYESATSSSSKGKAAYVENEEGEVERSATPATAPISIPISSPSADDDFVDLDEELEVLSANGNDSEDDGFLTDEEYDILDASDQETVVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P860</accession>
    <name>A0A9Q8P860_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761180.1">
        <property type="nucleotide sequence ID" value="XM_047903315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P860"/>
    <dbReference type="GeneID" id="71984045"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04167"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="273" mass="31243" checksum="B6EE7C26A6986E49" modified="2023-09-13" version="1">MADPSASPEPARKSLKQMTLSETIEKNSTMPPELWTSVLELAFTYNRLINICGARGLIWLIAQVERVFDAQEPYKTMQDEAVNALLANNIFTYRTTVIESNPGRRGVMIRPSAPSWTSEEVELLSKIKRLHIRVESKAYIPPQTTRFRQPGVWHFKGKEIIRRLLSICGALESVIVCFDLTYVGEQAVRRGVFPVREVLDTVFENTAAHRGFVTSSDRYTLWLEDKGGWRCGARPTSIADVERFLRREWPNDKMVLKVEIPAREGETRDRTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8L8</accession>
    <name>A0A9Q8P8L8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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            <begin position="48"/>
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            <begin position="18"/>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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</entry>
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        <name type="scientific">Passalora fulva</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        <source>
            <dbReference type="EMBL" id="UJO18030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB67</accession>
    <name>A0A9Q8PB67_PASFU</name>
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            <fullName evidence="15">Cysteine synthase 1</fullName>
            <ecNumber evidence="5">2.5.1.47</ecNumber>
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        <alternativeName>
            <fullName evidence="17">O-acetylserine sulfhydrylase 1</fullName>
        </alternativeName>
        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_07086</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine.</text>
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    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
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            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:136856"/>
        </reaction>
    </comment>
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            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="VVTVFWD"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
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        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:cysteine biosynthetic process from serine"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Cysteine synthase (o-acetylserine)"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
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    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="19">
        <location>
            <begin position="53"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00050981"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00058228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00072087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00078262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00079147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00081847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO19265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="384" mass="41311" checksum="1F310A41E865159F" modified="2023-09-13" version="1">MFARTALRAVTKPAAFTSIRQASALAGNVEAMNPRGIAISSAQRIAQNGFISAIGNTPLIRMKKLSEETACDILAKAEFQNPGGSVKDRAALYLVQDAEKKGLIKPGGTVVEGTAGNTGIGLAHVCRSKGYKLVIYMPDTQSQGKIDLLRLLGAEVYPVPAVAFENPDNYNWQAKRHAETLHNAVWTNQFDNTANRQAHIETTGPEIWAQTQGNVDAFTCASGTAGTIAGCTRYLKEVSNGKVKCYVADPPGSVIYTYLSSGGKMVERKGSSITEGIGQGRITDNLKPDIDLLDGALHIADEKSIEMVYRCLDEEGLYLGASSCLNVAAARHLAEKLGPGHTIVTILCDGAYRYADGLFSRKWLESKGLVNAVPEHLHKYIVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBI0</accession>
    <name>A0A9Q8PBI0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763762.1">
        <property type="nucleotide sequence ID" value="XM_047905925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBI0"/>
    <dbReference type="GeneID" id="71986655"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06777"/>
    <dbReference type="OMA" id="IGSEYIW"/>
    <dbReference type="OrthoDB" id="3648185at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="231" mass="26286" checksum="2FB3E66EBDC8EF6B" modified="2023-09-13" version="1">MAPTTTERVFGIGELVESILLHLPDTPVDKQHEPLFQLFVLQSLNRTTNLAIKSSKRLRQHMFLEPRDTTPMAARMPTTWLLRQVGIAVVLPLDAALLDIRIEGLGLNGVVNCKVQGYLRDLITAFSKVEAYRSLAWVHLKAPEQGVSIKNLDMRVQIGSEYIWDFGAGAKELTRWWRDGVLNTMWAERWEFGEEVTVGDLLDKYLEVMRRTPAEHRLQQSVHAKAISGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBJ3</accession>
    <name>A0A9Q8PBJ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_06750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763825.1">
        <property type="nucleotide sequence ID" value="XM_047905898.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71986628"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06750"/>
    <dbReference type="OMA" id="SHMFIEC"/>
    <dbReference type="OrthoDB" id="160645at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="1182"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2033" mass="196343" checksum="B23823479F2C35EB" modified="2023-09-13" version="1">MVRLNEVAVAGLALCADSANALPGLHRRQIGLNGLFGGPQPAPAADLPTQLDCYFFGGLFFGGCNSGSGSPAPAATSAAAAVKSTTTVIAGVLTTTMSAAPRVSSTSSVSVVPVISTSAQSTLAVIPALSSAIAASNLPAAGSLAGMINSVAPSVTVPGETSNIQSLAGALTSAINASNLGHASSLVSALASIGSVAPSLGSGLPSASLAVPTRSVGSALSASSILPSTIVPNVQSALPALSSAVANSDLPAASQIAGSLIPAASGIPQASSLAHALTSALASSNLPAASSIVPAFTSALAASSNLPSAGLPSGSGVPNVQSAIPALTSAIAASNAPQASSIAGGLVPVASGNPQASSLAHALTSALASSNLPAASSIVPALTSALAASSALPTAALPGTSSVPNIQSAIPALTSALAQSNVDQASQIASGLASAASGHTQVSSIIQALSSAIAASNIQGASSIVPALTSALAGVSSASALSSLPTSVPAGLASSVSVPSNGIPTGALTSSVSIASGQLSSALPSLAVPTPGSIGLVGALTSALAASNIPQASQVANQIASVVNATPVPGASHVSQLASALTSAFANSQIPVASSLAGVLNSAGPSSAVSSIAFGLPTNAPASGAAQPSALTSALANSNINQASQIASQIASLVGATSLPNASAISHIASALTSAIAATSVPQASSLAGALNSALSSLSLPAGPSAVPSAGTAIPSDLPGALTSALGASNIPQASQIASQIASAVSATSLPNAPAISHIASALTSAIAATSIPQASSLAGALNSALSQSSLAGLPTSALPSSLPASAGLPSSSVSSIPTSLPASLAAPAASVLSSALAFQSIASTAISSIAALPPSAIPTAIQSLGLPSGVASSLGNLATSALASGSALLTGAVTVPVSALPTGLVSSLGSLVSSASLSNGAPGWVIPTSAIPSGLASSLAGLGSSATPSLSTSAPALTLPSSVVPTGLLSSLGSIASQATVSSTLVVVIPTSARPSSLASSLGSIASSQVQALSTISASSTTSSPASPNQTCTANGVTYTSGQQINGYTIHCAQDNSQPGSEVFPVQSGGFSKCPAACDAQAGCVGWTYSGEDSGNCYLKTAEGTYSSAPNSIVSGFKSGSSNGSGVSSSVAPPALTSGVSVFTLPGGILVTVPASVGSASSTAAPSGTSSAPVSSTLASCDQLGNGSQHSGYTLACNTDAPGSDMGSAPGSSFADCFNKCSAFAGCTAFSFLGGSGAGTCYLKNRYAPSASNPNNADSGFLSMPSQTSGGSCEALTGNQGSGQHIDSMGYVYNTTCKHDIPGGNIAAFASPTFEGCFAACDRQAGCVGFSWLRDDGPGTCYLKGPQGNMLSTSVADVAVKVGFLGAQNTASGIGSASLAFRPLSGVFDATTVVTVFPTTVPSIVTIISVTSTSPASASASTVTIVMPTGLTASCQSLGSGNLIGQYKSRCGTDALGGDFMNAHADSFAGCIPLCDAQAQCIGFAFVGGSGAGTCYLKSVHEPETTNSNVDIAFKQSVGVALPTNAQMTGAGGATTTRTIGSVIPSGVIPGATGEVPVSMLASGQAVPSGAVPIAIGPSGVAIVGPTSALMGVIPSLMIFTAFAPPTPTFGLPSVIPMPLASSIILSTSTIPALASVVTHSVIVSSMAPSATIPGVGAVPISLIPFGSEIPSGVFSVGTAQSEAVIMAPTSAFPSGVGVVPTSRPVLDITAALSSVAGHMSSIALGNPSTAAPAISSAQAALSSIAAGASILHTPGQNGNFGLALSSATHALSSLAGALATSVPQPAIPTTLLSSFVVVQPIATTTHFSGLTGAAYPATVIGNPILHTVTAALQSTVTAIQAPVPVQTASGEICNPVQPGLALPASQCNIFNEHKHRHHYLKASIRHGNPALDGVFVAAPTVLGHEVARVTRDQGKAAHAVYDHLTRSYFLHDALEEAELCEYHGLALITHGATELGPVGLILGAATGGAELYDGVFGFLDLIGSQAPFSFGSWYVCEDDMTLKYLRKGWQRGTVQNVDFGKCAAVVLHRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCZ7</accession>
    <name>A0A9Q8PCZ7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764637.1">
        <property type="nucleotide sequence ID" value="XM_047909289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCZ7"/>
    <dbReference type="GeneID" id="71990019"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10141"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000007">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="25"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="267" mass="29077" checksum="15A019E8B83FAE12" modified="2023-09-13" version="1">MSESAEPNGEAMRVDPARAKVLVENLQYVAQKVDAVRGSRNVRLIAVSKLKPATDILALHESETKHADFGENYSDELIEKAGLLPKSIRWHMIGGLQTNKCKPLASKVPNLWCVSSVDTTKKANELEKGRKTLAEKESLTEKLRVLVQVNTSGEESKSGVEPKEATQLCKHVREQCPSLQLAGLMTIGAIARSREASSAEAMNKDFVTLRETRDKVAGELGMQTSELALSMGMSSDFEAAIAQGSDEVRVGTTIFGERPAKKDAKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDC2</accession>
    <name>A0A9Q8PDC2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="FTDMFPI"/>
    <dbReference type="OrthoDB" id="2098203at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="189" mass="22484" checksum="0AF7AD10518EAE64" modified="2023-09-13" version="1">MAAMKTPSMSLLRLFSPAIRSDTLPWTARGCLAQTQQQTAHFSSTSQLQKRNQGGVKKDPRIVQIRYHLQHPLTPRPLRFSRNRALRHWTIHRAWHRFQDTLRTNRERELERQYNSMYYACEELRKIDDRGMTAEERERVGIEGDSKEMGRLYRIAMMKNEIWDEVPIEYARIQTETPPRGGWNEAWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE95</accession>
    <name>A0A9Q8PE95_PASFU</name>
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        <submittedName>
            <fullName evidence="4">Actin-depolymerizing factor gmf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="MEVQDED"/>
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        <property type="component" value="Chromosome 8"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="P:negative regulation of Arp2/3 complex-mediated actin nucleation"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="100" mass="11309" checksum="9599F65832BA5797" modified="2023-09-13" version="1">MEIKPEDNQVYTNIQELADELPDNTPRYILLSYPLTMPSGRLSVPYVMINYLPSTSNSENRMLYAGAKELMKNTAEAGRIIEIDNAEDLEGIEEILKGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF91</accession>
    <name>A0A9Q8PF91_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3669 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765703.1">
        <property type="nucleotide sequence ID" value="XM_047910632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF91"/>
    <dbReference type="GeneID" id="71991362"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11484"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022137">
        <property type="entry name" value="Znf_prot_DUF3669"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40780">
        <property type="entry name" value="DUF3669 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40780:SF2">
        <property type="entry name" value="DUF3669 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="294" mass="31735" checksum="AB2477C92C21AF82" modified="2023-09-13" version="1">MDITRFQEMQLPGKEYAEAIGSAMAVLHWEAQIDCNDIEFVLGSSPTTLERARMTSSELKELKPETSTYNAVYGPSIVNFEKRVMSLWAMDFDQCKSISMDAAGLDLAVSALERNNYIPRPGSGRAYQEDLSVAFRETYLKVSKTILPAKYRPLADQFISKMGAACARYYNKYPDQKESGTSRSASASKGFGAPNPAANTSRRGDERSWSQNDESKFSSRGGGGGNASTRSRDDDRGRGGREGDSRGRGSRGEGDQGSGGQGSGNRGSGSRGSGRGMADVDLSRRGIRGGRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFF2</accession>
    <name>A0A9Q8PFF2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765867.1">
        <property type="nucleotide sequence ID" value="XM_047908578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFF2"/>
    <dbReference type="GeneID" id="71989308"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09430"/>
    <dbReference type="OrthoDB" id="2122015at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007008">
        <property type="term" value="P:outer mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035195">
        <property type="entry name" value="Emr1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17237">
        <property type="entry name" value="Emr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="56" mass="6458" checksum="25F7676412789BAF" modified="2023-09-13" version="1">MPSNLPNLRRLFVEARAEVEESAYSRNAFYNLVLFMSSVAIFSLAAQRMNGQRYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFM1</accession>
    <name>A0A9Q8PFM1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765893.1">
        <property type="nucleotide sequence ID" value="XM_047908273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFM1"/>
    <dbReference type="GeneID" id="71989003"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09125"/>
    <dbReference type="OMA" id="KELDGWC"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="370" mass="40966" checksum="E46C769345419E8B" modified="2023-09-13" version="1">MAEDTHTLKATCHCGNAKHAISVERDQLPLKSDMCHCTSCRHTTGLLGFAAATLPDNYEPDQLLLDKLTAFDSSKNIKHFFCSNCGTGLLSRCIGSGAVEWLVHTGTLEQGDASIYRLDAHIFVEDTLDGGLANFLTEVDGRRVKRHAPYFDSEELPLGWTASDRPEIQKPGPDERLHGYCKCGGVEFWLAPPSASSSAGIHKDDEFPKDRYISSDDEVFWMTDNQTKYQAALCPCDSCRLAGNGQPFAQWAYVPTGAVLIDPAGNVPIPDNLQWGTLKSCRTANASQHFCGRCGAIVFWNLDARSYLKDFGVGLFDSPDGARAESWFHWRTAELRHREDGLRRAKELTLAVEKGLKEYEENVQSNIGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFP7</accession>
    <name>A0A9Q8PFP7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-gulonate 3-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">L-gulonate 3-dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_09110</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.45" evidence="8"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766014.1">
        <property type="nucleotide sequence ID" value="XM_047908258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFP7"/>
    <dbReference type="GeneID" id="71988988"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09110"/>
    <dbReference type="OMA" id="ALRWSFM"/>
    <dbReference type="OrthoDB" id="2021159at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050104">
        <property type="term" value="F:L-gulonate 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF1">
        <property type="entry name" value="LAMBDA-CRYSTALLIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="12">
        <location>
            <begin position="11"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="186"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO21648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="312" mass="33643" checksum="03F701AC6A851771" modified="2023-09-13" version="1">MASETPESTEITLIGAGTIGLSFAALHLTSDPTCLVTIHDKRPDLQSYISTHLPSYIPEAALESCTKRISYADSLQHAVKSADIIQEQGPENAEFKTSLWPEIEKHAPQNALLWSSTSGIPASVQVEGMRDKTRLLVVHPYNPPHIMPLLELVPSPSTSQDVVARTLNCWRARGRTPVVIKKECTGFVANRLAFALFREACSLAAQGVASVEDIDEIVTSSMGPRWAVAGPFKAYYAGGGEGGLRSFMEKIGGTVGECWDASDEGVRKGGIRVGAEWQEGVCEQAEDAYGVVDTGDRDAKTRRVLEAVSSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFV0</accession>
    <name>A0A9Q8PFV0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="13">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_09618</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 13">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766205.1">
        <property type="nucleotide sequence ID" value="XM_047908766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFV0"/>
    <dbReference type="GeneID" id="71989496"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09618"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000097">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF57">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 13" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 12 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="14">
        <location>
            <begin position="49"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00002224"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO21839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="520" mass="57457" checksum="8C7C23B0FA149B21" modified="2023-09-13" version="1">MSTFWTTARASSSFVCRACRRPSTAQSFQAQSWRAMSSEGQQKLLSSNLEQADPSIFDIIRKEKRRQKHFINLIPSENFTSQAVLDALGSIMQNKYSEGYPGARYYGGNEFIDEAERLCQQRALETFGLKESEWGVNVQPLSGSPANLYAYSALLNTHDRIMGLDLPHGGHLSHGYQIPGKKISAISKYFETLPYRLDESTGLIDYEKLEELAILYRPKIIIAGTSAYSRLIDYDRFRKVADKVGSYLLSDMAHISGLVAGGVIPSPFEYSDVVTTTTHKSLRGPRGAMIFFRKGVRSVNKKGEQVMYDLEQPINASVFPGHQGGPHNHTITALAVALHQAQQPEFKEYQKQVLENAKALAARLGGEKGKGGLGYNIVSGGTDNHLVLVDLKDKDIDGARVERILELVGVAANKNTVPGDKSAMKPGGIRMGTPAMTTRGFNPDDWKRVADIVHRAVGITKTLNGKAKEAAEKSGRKNPASVNAFKDYVKEGEEIVEIVELRREVEDWVGTFSLPWEKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGE0</accession>
    <name>A0A9Q8PGE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047908329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGE0"/>
    <dbReference type="GeneID" id="71989059"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09181"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="255" mass="28326" checksum="A5A96B1569BD2DFE" modified="2023-09-13" version="1">MPVLAYTQTMISPPPPGPCSKASSTAPHIQRPSHLNGENSNRRRNPPIQENSNRRHDPSEDENPNRERDPSEEENPNRRRDAESPPPTTRTGTTVRRRKRDRLKRFFRRLLFPIPSSKPRMKSLSSRKKSRSNPFYQTPNSSSTGSICQEPDRNASFSTLNSLERLEVEIEVKRRKREAKMAAKYATTSLPQSSQCAPLIETPGATRVSVEEPAAKPAEPTEGQAEASTAPTDGPKPQGAGPKTQTTSQHLTADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGI1</accession>
    <name>A0A9Q8PGI1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_09336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766360.1">
        <property type="nucleotide sequence ID" value="XM_047908484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGI1"/>
    <dbReference type="GeneID" id="71989214"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09336"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="655"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO21994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="676" mass="74511" checksum="72A9E0784926FF40" modified="2023-09-13" version="1">MPASHTIAAPANMAPIHNNKLHEQSLHSSAMELKYAQSTHLVDIIAKDEDMRRLRFDIHVMEDDNNELRDLLTQEEDRSNNFEVLVNENLARAEEAEARLQDVETVLRVREQEVGTLQAEAKALKTTAQDSETFLTEKLALTRELSVLRPELEHLKAQAASTEALMTEKLELQRLVSNMQCDVENAKRDLKRAQAKRRNTGVEIAQEEQVEDLKRQLAKEKRARQRAEQAAETTQMDSSVDDVRKELAREKRARQKAEEELEAVQENTQVEDVRKDLLKEKKAKQKLEGTVETLRKELERERKVAARAAKRADATAETDEQLDEARQELSAERKDRTKTEKAMQKAAEEFEAQKQLLDEKLGQFRAKLKSTKEKLKETEAELEAAREEVAESKKGTKASAPAAKNTKKRNAAAFDADATTLGTPGDGHAAKRGRKAGAGIGEKSSFSMTPFLNKTASILPDSPADADEATEEEAEDVPSPTVEPAKIKKQPLAPKPASDGNIQKKPAGRPRKQKAALPALEIVTEEAEDVHSQGQENEPAAKPATKIRTKSADGSNEKAGAAEKKKKRKSLVDFASFNPEPEVKKKEKKSRKLGGTGKTLFDEEEESAAPAKALPGKMFLGGRGFGALGAGQKKAGGFLGASKIGSSMLMTAGDGDGFTFSPLKRRRGNLDDTLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGR3</accession>
    <name>A0A9Q8PGR3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_08874</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766549.1">
        <property type="nucleotide sequence ID" value="XM_047908022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGR3"/>
    <dbReference type="GeneID" id="71988752"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08874"/>
    <dbReference type="OrthoDB" id="3782245at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039537">
        <property type="entry name" value="Retrotran_Ty1/copia-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648">
        <property type="entry name" value="TRANSPOSASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648:SF11">
        <property type="entry name" value="TRANSPOSON TY4-P GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="13" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="16">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO22183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="140" mass="16373" checksum="2AC3AFDC902E5CCF" modified="2023-09-13" version="1">MWNFYKKTPKIWFSDQGGEFNNKELAREAQAEGIRWDFSAPYTPEQNGIAEASNKHFAMKHSCYITNRLYNLTAKKIPIQDFGEDLGLGVREVDLSNIRRFGCKAFRNLDNKQDSAKFMPRAEIWWYVGFQEDSSTNYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH72</accession>
    <name>A0A9Q8PH72_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_09150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766764.1">
        <property type="nucleotide sequence ID" value="XM_047908298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH72"/>
    <dbReference type="GeneID" id="71989028"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09150"/>
    <dbReference type="OrthoDB" id="413582at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000924">
        <property type="entry name" value="Cell division protein kinase (Ctk1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF576">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CSK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="103"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="399" mass="44027" checksum="E9359597E8F173DD" modified="2023-09-13" version="1">MADDWRRAVTFTVRLEHTTEIVTAYKQAHPDCDPGEAKKYAKTSEEAARKNALNLQEYHELCAKQVKLLLAQAQSHHPAEADPHVDEHIYPNLPVHGAAIGKYTNAEQFNDGLFSEVFRAADPDMADSNGKPRVVALKITTPAMEQPPHDSSREARLLVATKSEHVIELLETFRHSGHRFVLIFPYMPFDLNQLLHQQKLTPQSRQTVLRDLFAGLAHLHSLGIIHRDVKPSNILLASSAGPAYIADFGIAWSPSDPASEAADQKILDVGTTCYRPPELLFGHTSYGTKLDMWAAGCVAAQVVCLNGQTLFDAGDLGSELALIKSIFSTLGTPDLNSWPEAGNMPDWGKMNFVKYPAKSWEEILPTADESTRGLVSNLVCYESAARMSAEEALKHAYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHS6</accession>
    <name>A0A9Q8PHS6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_12054</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767023.1">
        <property type="nucleotide sequence ID" value="XM_047911202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHS6"/>
    <dbReference type="GeneID" id="71991932"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12054"/>
    <dbReference type="OrthoDB" id="567788at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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            <end position="89"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO22657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
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        </source>
    </evidence>
    <sequence length="318" mass="35122" checksum="4E3BEC745F7458E9" modified="2023-09-13" version="1">MDNIRNSQTVQNLANGPVAEKARNEADATKNEFGNLAASRQTPQTQTATGQDLTHYHSFFYNLLSWENPRATAISYAMIVAFVFTTRYVPVTRYALRVLYITLGVTAALEIAGKVILGEGLASKLRPRKYYTIPHENLESVLSDVEELTNFFVIEFQRIVFAENVYATVAAFVTAFLGYYLVKIMPAWGLVLLSTTVIYFAPLVYISNKELIDYHINNASNIVAEQTSQLREVAAQQTNNAVSSTSSLLKDYTGKAQEAIGQTKQAAVEKNIISPETAEKITPEKSVHDAEFPSAPKEEPSGPELTQAEEKTAEPIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8PID2_PASFU</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_12424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_12424"/>
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    </dbReference>
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        <location>
            <begin position="61"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="98" mass="11003" checksum="603BE4F11322219E" modified="2023-09-13" version="1">MVALIHVQQLGEAAFATSSQNGLSVETILESATIRKAAFDVRNEEHEIEAAINQWNDDVLDEHFNRSDDGDELDFDVEDVDEDDDFDPYPDTARDCEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PII3</accession>
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        <submittedName>
            <fullName evidence="5">Ribosomal RNA-processing protein 7</fullName>
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        <name evidence="5" type="ORF">CLAFUR5_11677</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
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        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71991555"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="15"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
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            <begin position="194"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="35039" checksum="58528D36FBE20ECD" modified="2023-09-13" version="1">MMVPMAGQKIPPTVHDFVILPLRLPPQPSYPKEATHYLYLRANAPKVSTDDTPREVFLVNVPSDATETHIRSLFADQLGGARIENVAFEGARVGRGISAPVAPTQSKKRKRGIDENEATTEAEVGLLPETWERDIHRSGATAIVTFVDQASAQLALKEAKRATKSKRDITWGAGISSKSAPLGHARYLSHHHLRYPDHALLQQSVDSFMTAFSAQEEARARALAKQRSEPDADGFITVTRGGRSGPAREEEVKAKEAEFKRREKSRIKDDFYRFQVREKRKAHAKDLVRGFEEDQRRVEEMKKRRGRIRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJQ2</accession>
    <name>A0A9Q8PJQ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12579</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768041.1">
        <property type="nucleotide sequence ID" value="XM_047911727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJQ2"/>
    <dbReference type="GeneID" id="71992457"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12579"/>
    <dbReference type="OrthoDB" id="9971669at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="5">
        <location>
            <begin position="110"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="201" mass="21443" checksum="A764CA02982FE0C4" modified="2023-09-13" version="1">MACSAAVHTTYEPTSSRSDSSRHASYLSAHKYHPATSSASLRCPGQAQSRPLSQCRSPTRLFCALVMSSQAPCRHAEALQPFKTPSPARATQPDVPYLKDSGNDALNTMCQSNSSWMYWTLAQCVAHQAIGGCGLRTGDLLATGTVSGEKEHGCLLEFMKPGTTPPREYLEDGETVVLSGYCGEVVGFGDCVATLLPAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK26</accession>
    <name>A0A9Q8PK26_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768455.1">
        <property type="nucleotide sequence ID" value="XM_047911976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK26"/>
    <dbReference type="GeneID" id="71992706"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12828"/>
    <dbReference type="OrthoDB" id="5210591at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF59">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37241" checksum="C61B453773608E3C" modified="2023-09-13" version="1">MTVLLSPISSPPQPIFKPLPPGMSRSPDRGTVHQVALKALQIKAVRIERLDGSVFRNLRLQPTSEYFYVLKCRPSSHIRLLGQEEERLQTEALVLQSLQSRSDMLVPRLIQYHPTTIPMGSPYLINGPFKGSILSDIEASLSRQAFSSIDKSLGQYVRQLSHISGPAFGAISPGTPPASPAWSRCFAALLETILRDGEDALVSLPYDFIRNQVRRHRQVLDQISQPRLVLLEMAKDENVLVNTNDYTFAGIVDWSTAIWGDPFMSDCFHKPRVGFAEGFGRLPNRDANERIRQYLYGLYHSLLAVVRHCYRPSGDGDELAARRTLVSADGEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKL1</accession>
    <name>A0A9Q8PKL1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_13838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768503.1">
        <property type="nucleotide sequence ID" value="XM_047912986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKL1"/>
    <dbReference type="GeneID" id="71993716"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13838"/>
    <dbReference type="OrthoDB" id="10667507at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040393654" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="795"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO24137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1193" mass="123593" checksum="419345312626770A" modified="2023-09-13" version="1">MRASSILALFASSSLLTPTVSAASKDEHRPIFPPCDDKCRHEYRDDLALTNAATAATDALESFAAWGECGSQDWCTDAVNMIITKSAVHAVANSSMLVPPKEDVEYAKHLLTVGNTAAMNTAFDMYNMLDAMRNNDHKILKEHWNATAIHDKHSYSTYNEWVNGAAHVPRTPPPKAEKGEFVLPQGPDKVLWNAGMLYQQLQQPPALDEIRFGAFLAWQDGVGQAGTSAPVSSGSAVPTQASPATVLTITVSNVRNPGTSQAVSLAPSLAITSPQSSTMSRTSAAGILSFARSSSIASTGEAPLLTTSIASTASETQTLGTRTTSSSSIAAIIPPDHSSARPGSIVSTGEAPLLTTSIAGTASETQTLGTRTTSSSSIAAITPLDHSSALPGSIASTSEPPSLTAITILKSSAAVTAPGDHSSAHPSSTPSTGAAPPLTIISASSASEPQTGGTHTTSSSSSAVALPPPKSHHGDKKDLAALGALAVLPAVGALAVGVKPAYVKYNNWWNSNTPKIPTRPPNIVEDNPLEYAAHTAQEWAETMAQEAGSSYQVAEEVLAKIPKTEQWVDNVLQNDFYEPIPKDNIVFDNLAEKFTSQINKAMRIGGREVAFFEDKFVAQSVAVANTAQAVLDGAGGAASALSSPLGFFSNLVNHALRRAGNWHSPRSYHSSDWETIDGSSGSSSGGSSGSSSGGSSSGGSSSGGSSSGGDPGDWETDPESSSEGSSGGSSSGGDPGDWKTDPESSSGGSSGGSSSGGDPGDWETDPESSSGGSAGGSAGGLSPGAPPPGISGIFSPGGGIGGIFGGGHGGGHGGGHGGGHGGGHGGHSGGGSGGSPPGNGEGSHPTANPPKGPGHESAISGTAHPQPTGEPPNDPDQKSSFQTTVNPKPTGQPSNDPNQESTLASSGSITQPYITWNPFSTPTTFSTTTGIPSESTTQPYTWNPFSTGIPSESTQPYTWNPFSTGTQSRPPDIVIETPTPSTYSTWNPLSTGLPSESTTQPSTWNPFSTIIPSGPPAIVIGTPTSRGFTWPSPTTPTPISGLTITGGPTPLPGAQFEECTPTWSDMRITSWILPPKGGHPNYCFYTKDFAKYHYEAQEMGCLPNFRNRECRAKFFDRQIDGLSDVMPTDPSEPHECMDTWTEIHKGWWQVPPVGGNPQYCWLPQDQKVKKSAEAERKGCLPHFTTEWCRREYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKP7</accession>
    <name>A0A9Q8PKP7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768785.1">
        <property type="nucleotide sequence ID" value="XM_047912665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKP7"/>
    <dbReference type="GeneID" id="71993395"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13517"/>
    <dbReference type="OrthoDB" id="2943660at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040382627" evidence="1">
        <location>
            <begin position="19"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="100" mass="10475" checksum="963232F768DDC297" modified="2023-09-13" version="1">MVAITALLAIGLSTLTYAAPSPNTAPPSYNQPKPNKCGKIDAFLTGLPPNHPLVIEQGYNPTAVNNALRADQKNIIAAGYNVRYMLSGPEKGQGIVARSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL08</accession>
    <name>A0A9Q8PL08_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_13967</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="185" mass="21068" checksum="F230A20EAAF49D25" modified="2023-09-13" version="1">MNEHYDDAWVLPDEHEVESTDRFAERGISWDTDWDTADYEVESTDHSVDRGISSGTDWDTDDLGNDIEEAFKPASNVSTLQTSRPANDKEYSYSPVDTDQRCIRLLKPRRPCPGSGRIQCSLSTHILGEAPCYTALSYTWSRPDASCCISVDGKRAQVGKNLLRFFQMAQDFKHYRATLFWIDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMG7</accession>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
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    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
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        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="76"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="117"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO25142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="748" mass="78644" checksum="27320AB99FB370C3" modified="2023-09-13" version="1">MKVITVTALLAAAIANANIIFTFVQPTCRLTSTGPRGCFRGQTCMPDSTCAISPRGLIDIASVGPSLADASPPRADGPCGKDFDDATCDPKGEYGGCRSATGWCGDTEDHCLNSNGCQNGCASDAPDSDPPADEPSATTTSKPAGPASEPVIGPPPTSSGPQATGEATTDGSCGASNGGTICGDWALGSCCSAYGFCGSTSNHCGDGCQSGPCDSPPVPPAPGPSPAPSSPNPGSFDKKYGDSGVPAMHAALLPNGRVVFLDKVEDYSKLKLSNGENGFSAEYDSATGDTVALAYNTNAFCSGGSFLANGTVMSIGGNEPFADDDSVGDGFKGLRWLTRSAMDASFDGQDWIETEDTLDTARWYASVQTMPDGTLFVVSGSLTGLDPTQGYNNNPTYEILDKDGISHGGSIPMEILVKSQPYYMYPFMHLLNDGTVYVFVSKSSEIFDVAANETVKKFDELPGDYRTYPNTGGSVLLPLSSGNDWEADVVICGGGVWQGLDSPTDPSCGRIQPQSDDPSWEMDSMPEGRGMVEGVLLPDGTVAWVNGASRGAQGFLLAEDPTTTVLLYDPSAELGERWHTDATSDIPRLYHSVALLMLDGTVMIAGSNPVQMPVMQEDATDQNFTEYRVETYIPPYLSGDNADRRPTDIVVSSLDLVADSSTFEVNFTAPDDAKEVKVALYHGGFVTHSLHMSHRMLFLDIDGFVEGEKEQEIQVTMPPNNNVAPPGPYVVYVVVDGVPGVGQFVMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMT9</accession>
    <name>A0A9Q8PMT9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">37S ribosomal protein MRP2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769684.1">
        <property type="nucleotide sequence ID" value="XM_047913628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMT9"/>
    <dbReference type="GeneID" id="71994358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14480"/>
    <dbReference type="OMA" id="FGLCRNQ"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="13427" checksum="03B8BB32991F17D5" modified="2023-09-13" version="1">MSQFRPRRLDLSCFINNKIIRDHTKRKVFEQHEPERQALRYIIRNTSLPQRTRAQAQLQLTQMHCYTRSTQIKNRCMMGGKGRGVFSDFRMARFQFRINALAGRIPGVKKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQP3</accession>
    <name>A0A9Q8UQP3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763335.1">
        <property type="nucleotide sequence ID" value="XM_047905791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQP3"/>
    <dbReference type="GeneID" id="71986521"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06643"/>
    <dbReference type="OrthoDB" id="3353407at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="132" mass="16077" checksum="5F7F48A9D9E4D0A2" modified="2023-09-13" version="1">MDIWTNDQLYQDMLRIVPQEFRSISIQWNDKLFEDYIKHPEYDDVWNWDPNVRYTGNWYELLEGVSQLNQRFYVPLVHGSYDEFKRSTYDAVEKTAREHGYKPIWGEQSWDKQKQKPIGPKPLKPIEEDDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR49</accession>
    <name>A0A9Q8UR49_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763713.1">
        <property type="nucleotide sequence ID" value="XM_047906118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR49"/>
    <dbReference type="GeneID" id="71986848"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06970"/>
    <dbReference type="OMA" id="EPANPHM"/>
    <dbReference type="OrthoDB" id="4828117at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="17288" checksum="E34501C286922428" modified="2023-09-13" version="1">MAKGTLDWNSPETWQRVVAAVIATGVKIDLKQTAAYFGTTYDTLENRFRKIKKEATTLKDEIDNGERSGVTTPSRTKSASSTPRKPKTPKKDPLSTVTNGKVTKSTPKSKKGSIKQENLEDGLSFDDMSGLADGNDMSFTPNAGFDYGNGLGDNDFPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URL4</accession>
    <name>A0A9Q8URL4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ASST-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764207.1">
        <property type="nucleotide sequence ID" value="XM_047909395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URL4"/>
    <dbReference type="GeneID" id="71990125"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10247"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040169122" description="ASST-domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO19841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="68714" checksum="AE699F5DF3BEFCB4" modified="2023-09-13" version="1">MYAVAFPIWAFLHLVLTSLVLVKASHPVIGPPPSLLPLKEPPPGEVFIQDEDFNQAAYGNYVLQTFNSTNVSVPRMNMMKPFTACDDGSYIFVTPRGEIAGRPTAAIYDVSGSLIWTPTVDFGEIYNFQVQMYKNELYLTFWPGSNDEAHGEGQYYMYDKHYNLVRNTSASNNLSADLHSFSITPENTVLLTIYEKVETDLAGILGQPSRFKQCMWDCLFQEFDLETGEVVFQWRASEHFEQKESYISHRPATEYDPWDMLHINMVEKDVAGNYLVSLRHLRCIAYISGEIGEVLWKLGGKRNMFEDLSGGEATNFVGQHDAHWDIVGQYITLFDNRADWQDEAEHVSKGKRIEIDTDKMTAKLNITYVHPENIFTFSQGSYQTLPNGNVLLGYGYTGALAEFAANGTLLCDAYLQPSSRFSSEEVQSYRNLKLNWTGIPTTLPSVVLENRTLYVSWLGSTEVRSWALQDSSDDDNDFGIVLEEPKSGFETGVILEHDLPLRRYVRLVALDIDRRELAASELIDVGDLATTHMEDVDTPLDDIDDEVQALKIEKQLQDLGALLGFALMALVAALLVLLARTRPQIIPDMWRGKEEDFGLDLPTLRNVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URU7</accession>
    <name>A0A9Q8URU7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Biotin--protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_10752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764462.1">
        <property type="nucleotide sequence ID" value="XM_047909900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URU7"/>
    <dbReference type="GeneID" id="71990630"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10752"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03144">
        <property type="entry name" value="GATase1_ScBLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="4">
        <location>
            <begin position="427"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO20096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="700" mass="76107" checksum="78513EBB0E8FAE66" modified="2023-09-13" version="1">MSSQKRVNVLIYAGAGASLSSVRHATWSLRRLLGPHYSIQAISADQILKEPWPNTCALLVFPGGADTGYCRALDGAGNRRIKQYVRMGGKYLGLCAGGYYGSSKCEFEVGKKGMEVVGDRDLAFFPGTCRGLAFPGFVYQSEAGARAVELSISETAFPHTVLDDFISYYNGGGVFVDAEKYAEQGVEVLAQYHEELNVEGGEAKAAVVYCKVGEGAAILTGPHPEFAGNNLNRTEESNPNYASLVDTLLADDEKRTEFMKASLKRLGLEVSEDTLAVPSLSRLHLSAAQPGQIEELLQSWQKAGLVSSEHDGDFIGGEQDTFKVEKDDSWNMANMKDALPSPVKKAADVLMDAVSTPSKAKPRPSATTQESDRAQADPSPDRPLDYDALTKGMTLHVKSLPDLKATPHFSHHQFFHHLKTIQAKQPGISGDFGRILMYGEVVTSTQTLLEKNTTLLSHLPIGTTCTATTQISGRGRGTNVWVSPPGTLVFSTVMKHSMSNKAAQVVFVQYIAALAIVAGIQNYGSGYEKLPIRLKWPNDIYALKPTSDPSREEYVKIGGILVNSSYSGGDYTLIVGIGLNLDNAAPTTSINQLAAKQSLEPLTPEPLLASILTQFEMLFAKFCVNGFDQRFESQYYESWLHTDQLVTLEMEGNVKARIKGITSDYGLLVAEEEGGAGKRFMLQSDGNSFDFFRGLVRVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US42</accession>
    <name>A0A9Q8US42_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764835.1">
        <property type="nucleotide sequence ID" value="XM_047909072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US42"/>
    <dbReference type="GeneID" id="71989802"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09924"/>
    <dbReference type="OrthoDB" id="3646241at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="368" mass="40977" checksum="9F28A0B2CF71A118" modified="2023-09-13" version="1">MAIPSRKDFFADLIQHDCPICYARVVGPVQTTCSHIFCAKCATKWFETSNTCPACRKVLYEKEMAEQDEDEDDEESDEGEDSDEDPQLFDTLWDLLETEDREAEESSSLPASSGRLRDGHENHRLLGTISDAAQPRRQVPLEDTFSRRITVLAHATAASSLQSPAVSSSRLQSDHAATNSFQWPLAFDYTSGDGSPAAAPSTIANSSTSPPTLEALQGRLPEDATQPAQSSCTLLSYICEDMFVTQSWQRPRYVTLSVANVHIHARPAFSEASELSFEKFVSRLRYHGIRVGPLEEVVLNGYEVSDQVTFERVIERATKAEMQRQRPVDPNSGGPTIVLECRALLQPGIWRECDREPDAWKESRSGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USA1</accession>
    <name>A0A9Q8USA1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764927.1">
        <property type="nucleotide sequence ID" value="XM_047909987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USA1"/>
    <dbReference type="GeneID" id="71990717"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10839"/>
    <dbReference type="OrthoDB" id="10680668at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="44282" checksum="F0037F1618B73B62" modified="2023-09-13" version="1">MAESKEKAKEKVNHFSKLALELFENIVKDVNPKDLLTIRATSRECAAKVAKVYAKEHFTGLLLHLHDDRSVEKCLAICKHPLLGPAVRTFTISIDPCDRGNKWLDDRLCTVEHRHSTRGPTTADPEPYEEFITRLQQDAEWHVIIELFTNMADACQVSALRIVGHERYQSTFAGGYHDFDLEGDPDWACAHAFAGIMYCLDRSNLHVDTLEIDKDARYAMPMCELWDYFDMFARVMSPVESLSLVLWRRHGTLPADAEMLNQLLAGLASSTTIRHLYIDCQSCENIDLATVFPIEDSGFPNLESLHLQGNDQLMFDVPVLVDFVTSHQRTLQRLELHSLCVEPNGLEDDGWDLMEEGVAKNIRRLTGLEDVTVDRDTEESWLDMMRQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USZ5</accession>
    <name>A0A9Q8USZ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UBP9-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765750.1">
        <property type="nucleotide sequence ID" value="XM_047910606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USZ5"/>
    <dbReference type="GeneID" id="71991336"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11458"/>
    <dbReference type="OMA" id="PMWLGDV"/>
    <dbReference type="OrthoDB" id="2421129at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17041">
        <property type="entry name" value="Ubl_WDR48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001614">
        <property type="entry name" value="WD repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051246">
        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021772">
        <property type="entry name" value="WDR48/Bun107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11816">
        <property type="entry name" value="DUF3337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="218"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="584"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="639"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="681"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="728"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="758"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1012"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO21384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1050" mass="114727" checksum="E80CC7D9E86DC2CE" modified="2023-09-13" version="1">MARKARQRISYVLPLANSAGGHRLGVNGLAVDSANSLLYSGGRDGVICAWDLNLDLENATALDYDAKIPQSQPTTFRNQVQAHTHWINDIALAHSNQALVSASSDVTVKVWRPAATDGMPPQTIGLHSDYVKTLAVPYSTCDWVASGGLDRKISLWDLNGAGQKLSIDVAADEAASMLSKEKGSVYALAATNSLLASGGPESTVRVWDCRTGKRVTKLVGHTDNIRDILVSQDGSTILTASSDRTVKVWSTIAGRCMFTLTMHDASVWSLFSSDPDLSIFYSSDKTGLIAKTDTRNTIELDEGLSVAVGQEHEGVHKVVTAGDCIWTATSRPSINRWRDVNTDNAEIEVPENYNTHRLSSATARSRYPSPPTKDSFSPMARAPTGKRQIPLKHALRLSNTAYFPTPLVEAGEANGITGGRRSTLETLNQDTVHSQPVRAQPELSVEGQNGLIKHVMLNDRKRVLTLDTAGEVVMWDLLKCVPIKSFGKRHLEDVKDEVTTTTAVANWCTVDTRTGSVAVVLEENTCFDAEMYADELDLDANLEFREDQRINLGKWVLRYLFNILISEETKRDEAFRKQLLGNKDQRLQRDNAPSSIQLPQMPMNGWQPDTRSATTPKANGNGAKALQTPGLNIGLATPGAQNSPLLSKTNTNNLPTTADNNFPERSSSQSHRQSGEKGTDYFSTSRIPNTELTTPGATSQPATTPHETHDPSTPTTEGPPKDGETPKKGMFGKKFSMGMSFSGMKKLGKTTTNTEKPAPTEEDKVETESDSHSSKTSNSRQVDDNFLGTIQKIRFAYEDSLQQQMQSQQAAENGLPITAKKIELPSAIAPSLPADTPVLKPPLNTTILIQEDRPEAGGVADLFEGTVGQLGEMADLVERAAPMWLAEVLLRNQIPAKDIVKISFILEPWQNELPSIAADGNNRLNANRMLRARKIMSYVADRIEPASAREEDSEEAHLKPEEYLELWCQNQLVPPTMTLMTIRSHLWRGGGDVVLYYKSNGRKTIRYAPPVQVSSGYPPTNTSAPERENSDAESGAPAVPVNAAAMWVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTB6</accession>
    <name>A0A9Q8UTB6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766125.1">
        <property type="nucleotide sequence ID" value="XM_047908251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTB6"/>
    <dbReference type="GeneID" id="71988981"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09103"/>
    <dbReference type="OrthoDB" id="5060046at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="35630" checksum="24461FEF3A6CCAF5" modified="2023-09-13" version="1">MAPIEDNAGAAESSAVQPPSLLERLVRLPEELQAGIFAQLSYQDALRLSQVNRYFHLKVEPEKCPEWEKAQFVFKAQFWEKHNMCVAERMKGPWGRGVVMRLTENNYACYRCYRVRPRTKFSLQMTKNFCAKETEKTFLSLIYRYCIDCGLADGKYRPGMTLSVTTDEIRDCRGNRDGAKPIITCKKLPLIVCRVCEEISPYEILLHARRCRECLNGTARWMANCRHEDVKRGLAKVKCLNCEAIQLVLDPGLACKHQCFEHARMCRKDWKDQQRHQKQMSKRERKAFGPGEELLEDDGEGLADVAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTV1</accession>
    <name>A0A9Q8UTV1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_09076</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766576.1">
        <property type="nucleotide sequence ID" value="XM_047908224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTV1"/>
    <dbReference type="GeneID" id="71988954"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09076"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046972">
        <property type="term" value="F:histone H4K16 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="16">
        <location>
            <begin position="22"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO22210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="329" mass="37069" checksum="2993365B625F320B" modified="2023-09-13" version="1">MAVTNMPAGSPTGAHRTPDKRSLTPNVSNVVLGNLHIKPWYPSFYPDDLVGGRKADWLYVCQWCFKYTPEIMKYSAHCKVCPMKSSPPHGEVIYETDEYIIHTLDGAEHKLYCQNLSLFAKLFLETKSVFFDASTFLYYTLILKPSKDELKASTASPMNALNPYGTVAGFFSKEKMSWDNNNLACILIFPPYQRRGLGQILMSSSYVLGRREGRFGGPERPLSALGRKSYVRFWCGEAARCILGGGSKRTLSVKEISEETWIMPEDVVLALKEMDVLETRKTASGSIVVNKGRVREWVEKNKISLEPVVEADGFVEEDISEDDSEEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UU95</accession>
    <name>A0A9Q8UU95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycoside hydrolase family 43 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767026.1">
        <property type="nucleotide sequence ID" value="XM_047911207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UU95"/>
    <dbReference type="GeneID" id="71991937"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12059"/>
    <dbReference type="OrthoDB" id="9970295at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18821">
        <property type="entry name" value="GH43_Pc3Gal43A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040471419" description="Glycoside hydrolase family 43 protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="49821" checksum="E61951C1E786746F" modified="2023-09-13" version="1">MIFSSSRASGLLSLTATAISAATFFPLINMTDTDGNAIQAHGGNIIQAQDGDGSWYWFGEDKTGETTSGHFIGVSCYSSPDFTTWTSKGHVLSPQAGTDISDSRIVERPKVLYNDKNSEYVMWFHGDSSNYGDAQIGVATSKTIDGQYKWKGNFKPFGNDSRDMTVWKDPDDGKAYLIFATSNNADFQIASLDDDYYNVTEALYTFRGVYQEAPGVFKIDGKFYLLFSPQDGWTPTDNGYHVADSMAGPWSEQTLLAPKGAYAYLTQNAYDITIKGSQETFYLYLGDHWNANNLGASTYAFYPVIYDGTGLSLHETGGWTLDVAAGTWKDLPFTIITADNSTTPDADLVKCNDGCAGGLAANMTTSTFTFTWDGTAGDKVLQILYTYPGAKNAFKHISATVDGKETTGWALLETTRANTIAQRAPLPLTLAQGSEVVLKLADGDKTAFLVDAVEVYDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUR4</accession>
    <name>A0A9Q8UUR4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rho-GTPase-activating protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767582.1">
        <property type="nucleotide sequence ID" value="XM_047911313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUR4"/>
    <dbReference type="GeneID" id="71992043"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12165"/>
    <dbReference type="OrthoDB" id="2155291at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04399">
        <property type="entry name" value="RhoGAP_fRGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000044">
        <property type="entry name" value="Rho-gtpase-activating protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000050">
        <property type="entry name" value="RhoGAP and Fes/CIP4 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF17">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN RGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="2"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="3">
        <location>
            <begin position="233"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="476"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="681"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="698"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="714"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="834"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="877"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="922"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="971"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="980" mass="108557" checksum="DB8047D7FB03B6E5" modified="2023-09-13" version="1">MSSFSSTFWSPDYAAGLGVLFGKLQQGVQENDQILTIARMRADAEDLYGQKLGDIETATNRIDGGFQRDDGASVKKAYEGVRSEMTQAAGNHRKIASNIRELVVNPFGRWCDQHAARVQNSQDDLQGRIKAHDRQAETVRQYRSAYYNKCRRVEDLDEEEKLAFQDPGAAAATGSPKNAPQTVPSIKVEEEEPEPEPVEIGDKTYMPDQLKKILTHVLDNIRLGEYKVPIIGTYQNVTTGAEIVDYIQNHLQANSVAYAEQIGQDLVNNGFLRLIGNVGSNFANSSKMQYQWRPKVFQLTGIPEKRPGLLNRTSTIMSQSSDSSVSGTPVIGDKVSEYLGGWNPLNNAHPNETPAERLRREAREADERYKAAVKKLDGMRCSLEEAMIDHMKFMERCELDRLKAIKSVILDFSGAVSNVIPSLQSTVDNMMLFQETVQPLSDLRYTLENYKTGSFLPKVTVYENYYNTNDEQTFGVDIEARARTDRKRVPLIITTILTFMDSHYPDLEGDEARRNVWLVDVPLGATHHLRNQINTGKRVEQALLEKYEVPIVASVLKLYLLELPDSLVSSHVYEIIKTVYTTTSQSASESARIQVIQSTLGQLRLANIATLDALTTHFTRLIELASADDEYVAKLAATMAPCIMRPKQETGLSMNEKYNVRLLKDLFQHKDAIFGELKRQSSLTHTNSGSTRQARAISTDESRRKEHMEERQRAIAAAQHGQAHAGGTRSRAASPSSESSTRGPVPAVPAVPAVPAHRRDRSRGPETRFPVSTTAAQTSERRVTSPTQSSTSSHRDSLSVPQSPLGGRAPPSSTTRDTTDRTNGFHQPPPSDLTDDHTPKARSSIDEAKRASGPAPRISASINAAGDFANHNHYYANSTDSNSNITSSSRPTSEASVPGIKPPTSKYRITNQDEVDSSSEATPTDSTPTKTDSFTRRTAYGRRGTGGLQRQSLVNKHDSAEPEQEQSKGVQLEDKPMDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUZ7</accession>
    <name>A0A9Q8UUZ7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767789.1">
        <property type="nucleotide sequence ID" value="XM_047912130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUZ7"/>
    <dbReference type="GeneID" id="71992860"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12982"/>
    <dbReference type="OrthoDB" id="3646601at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="172" mass="20185" checksum="5661B7F2AA6DA097" modified="2023-09-13" version="1">MLHEAELSRTQYFRLLDLPPEIWSNIGKLVVDNKPPLTYRAIWWARDERCSTPWTQQPAIARTCRILRQELLLYYYKNTPLRYVLAHTTSCQAVGIWLRAIGKHNRLLMGVISIGVWSYAPMDTLRKELSVDWKVEFELHELEYKRITPRLSNGMEASSKLEQYSIATVTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVF1</accession>
    <name>A0A9Q8UVF1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MIOREX complex component 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768269.1">
        <property type="nucleotide sequence ID" value="XM_047912391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVF1"/>
    <dbReference type="GeneID" id="71993121"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13243"/>
    <dbReference type="OMA" id="QGLYQTK"/>
    <dbReference type="OrthoDB" id="242766at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070131">
        <property type="term" value="P:positive regulation of mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="183"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO23903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="51658" checksum="B115A78FE0227467" modified="2023-09-13" version="1">MHNQAATLAGFAVIASRSWTTASPPLQSIGAGSATALPFRSATTMASTSAAHARKMPRNHFTSSRTSRQDDGQHPKRKAATKHATKNSLRKVALDAQRSRLVVRRSGKTRYVHPEADTKDVTAYCAAETYNLSRARWELQREGHAPDPCGTRLFPQVLHFQTQNSVVKEQDSGGERPQGAGDVFVFPSGCVVTWNVPELLARKIVTRYLPVAAGDTGHLDKMEIEDLEYIEDESKESSRIIGDTIILGTKPSDHYNLDSSPESAILDNDESRTPEVDTILAKIAFSSALARSTKLAVLENSLSHYFSTTRNIPLTLASGKKLKINRSQILQKTGELLLIRAQLNLYSELTDSLPDLFWDSPHELGLEGYYEMVGRALDVGVRIKVLNEKMDYASEIAGVLSQRLSEKHSSMLEWTIILLICIEVGFGIVHLSRESKMMDEMDEEKRTRELLQVWLQREVKGKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVS1</accession>
    <name>A0A9Q8UVS1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 17">Glutathione reductase</fullName>
            <ecNumber evidence="3 17">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_13681</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 17">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="14">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 17"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768571.1">
        <property type="nucleotide sequence ID" value="XM_047912829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVS1"/>
    <dbReference type="GeneID" id="71993559"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13681"/>
    <dbReference type="OMA" id="MSKHYDY"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000141">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 14 16" id="KW-0274">FAD</keyword>
    <keyword evidence="6 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0520">NAD</keyword>
    <keyword evidence="8 17" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11 16" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="19">
        <location>
            <begin position="9"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="18">
        <location>
            <begin position="352"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="15">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="UJO24205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="464" mass="50676" checksum="06A387596BA6A7C9" modified="2023-09-13" version="1">MAPIQKECDYLVIGGGSGGLASARRASGMYGAKVIAVENKRLGGTCVNVGCVPKKVTWNAANIAETIKDAKAYGFSVEQTAAFDWTGFTEKRAAYIKRLNGIYEKNLKNDKVEYLHGTASFQDPHSVRVELDDKSHVDIKAKKILVAVGGFPNIPSTEGADLGITSDGFFEISKQPKKVAVVGAGYIAVEMAGMFHALGTETHLFIRQDKFLRSFDPMIQDKVVAEYERQGIHLHKQSSQSKVEDIGDGWKRLHYKDQNGEGTMDIDCLLWAIGRSPELAKLNFDVTGVKLNDKGHITVDDYQNTNIDHIYALGDVCDKGFELTPVAIAAGRRLSDRLFGGQKDAKLVYENIPSVVFAHPEVGSVGLTEPEAREKYGDDVKVYDTSFTAMYYSMMEQEDKGPTAYKLICAGKDEKVVGLHILGSGSSEILQGFGVALKMGATKADFDRCVAIHPTSAEELVTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW35</accession>
    <name>A0A9Q8UW35_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768990.1">
        <property type="nucleotide sequence ID" value="XM_047913160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW35"/>
    <dbReference type="GeneID" id="71993890"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14012"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF2">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO24624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="30781" checksum="9313B4FC1F5F970B" modified="2023-09-13" version="1">MLKILEMYMRSCQVCGPCELSSAPSPSTIHQLLKMPYALAGRNVLITGGSRGLGAEIARKFAAERCNVAINYANNEQPAQDLAKELQSDHNVKTTVVKGDGGMVSDIKNCIKTTIDAFGGLDIIIGNAGFTKFSNFKDLDAMSYEEWDKCWNTNVKGNHALLKEALPTLNANPDGGVFILTSSVAGKSLSGSSMAYSVTKAAQIHLMKCLAHTQGPKIRVNAVLPGLLLTDWGNLYGDDRINGLKNVAALKKETELGDCAQMFVDIARNTSMTGQAVHVDSGLVPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWL9</accession>
    <name>A0A9Q8UWL9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
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    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="186" mass="20372" checksum="99C8D244950DE493" modified="2023-09-13" version="1">MAMAGDGEHLERALKGMILELLGGLKALRSQTGQIINRPVAAAAKKRTQEGQKLSQPTWAAVASQNPPPQKTAIKVYISDQQEQKEIEGLSGKEIIQKIGIQGIIGARKEKGGVLKLFTAQEQDRKRLETQKEWTVQLGKTAKVSHQQNMVIAHGMTTKFDIEGDLKRLQDQNQAVCPGLQITKAA</sequence>
</entry>
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        <lineage>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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            <begin position="30"/>
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            <begin position="83"/>
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        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO25135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="194" mass="21491" checksum="C9DCFE8A91689068" modified="2023-09-13" version="1">MDDKLDKNVESTDSSQKTFKQIMEEQQTEATKKTLAERKAREQDQLRQAPPPNRWQDVSRTPPGTSKAYGPPSIGPGRDQYDQSRNPDSSFGDWGQNQRGFLPKPTPGELWDNAVRRSSSSSTSQSYSDPSLPSKTPSAPGFAALSSRPPPPTVPSQGPSYGNRPARSMQQQGEGERKLSVDEIMAKPSWRRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXQ8</accession>
    <name>A0A1P8YXQ8_PASFU</name>
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        <recommendedName>
            <fullName evidence="6">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">CLAFUR5_10995</name>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX943131">
        <property type="protein sequence ID" value="AQA29302.1"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040573466" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="72"/>
            <end position="92"/>
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        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQA29302.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO20641.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="31134" checksum="6C2CE583EAE9C0CD" modified="2017-04-12" version="1">MRYTLLAMAAAITAVVADSDDCQATYKQCIADGYAEVKCSCDLTTCSGEDAARIRDYCATATANLPAPTKTSSATIITGTPGSQPSGQPPITAAEGSLPLGATCSDKKQCANGADCWGSNAGIIRRCGNFNGSCKEDSQCAYNTCNTDTGLCSGFLPTESYRANTVSSTGSAASSSATTYACNPAHQYPEGRQCVSTNGGLTLLPPTTTSASTATGTGYACNPAHQYPAGQVCTEIGGQLTLVTGGSPAATATATGVSPPVYGGSNSTTVRPTGTGAVNPSGSITPYQGSASVVETLSGLAALVAGVVAYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4L7</accession>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
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        <property type="protein sequence ID" value="UJO10792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047900734.1"/>
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        <property type="component" value="Chromosome 1"/>
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    <dbReference type="GO" id="GO:0005737">
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        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
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    <dbReference type="InterPro" id="IPR036400">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_M"/>
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    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="61991" checksum="CD4F718E65A73714" modified="2023-09-13" version="1">MSKTFTAVDVAAHKKPDDLYIIVDEDVYDLTKFQDDHPGGKKILQRVAGKDASKQFWKYHNESILKKYQGQLQVGSLDSKPKPAQAPTPPATPPPAEKKEAAVPTAESGTLGIQPQAAPEEVEAMDQFGDMVPYADPSWYQSYHTPYFNQTHADLRAEVRQWVEDEVMANVTEWDEAKKVPDSIYKQMGERGYLAGLMGLHHWPKEYTKHSIKSVPAEKWDLFHEMLLTDELSRCGSGGFVWNVIGGFGIGAPPLVKHGKKALKDRIIPGILNGDKRICLAITEPDAGSDVANLTCEAKLTEDGKHYIVNGEKKWITNGIWCDYFTTAVRTGGEGMGGVSCLLIEREFEGVSTRRMDCQGVWSSGTTYVTFEDVKVPVENLIGKENQGFKVIMTNFNHERIGIIIQCIRFSRVCYEESIKYAHKRRTFGQKLIEHPVIRLKLAHMARQIEASYAWMESLIYQCQKMNETEAMLKLGGAIAGLKAQATTTFEFCAREASQIFGGLSYSRGGQGAKVERLYRDVRAYAIPGGSEEIMLDLSIRQALRVHKVLGMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L553</accession>
    <name>A0A9Q8L553_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily multidrug transporter mfsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_01190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755441.1">
        <property type="nucleotide sequence ID" value="XM_047900338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L553"/>
    <dbReference type="GeneID" id="71981068"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01190"/>
    <dbReference type="OMA" id="RTIGPMV"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF6">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="138"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO11075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="670" mass="72487" checksum="0D10F08BF6DDB78D" modified="2023-09-13" version="1">MNIDNEASHRPASSSSSVHELDSAATTLLVSPTTSKGHSFEEARLYTDIELHRLEDNIRKRRQSLDSDHEPDSYDAASTTTNKHGHLVAHDTVALNQPSARAAHTLPDNDEPPPPSQARDANAKSQPVSWSSLPEKKQLAILTLARLSEPLTQTSLQAYMFYQLKSFTLPDGTAPSDSIVARQAGLLAAAFTGAQFLTAIMWGRLADWEGLGRKRVILIGLLGTAIGSLGFGFSGSFPVAIFWRAVGGMLNGNMGVMRTMISEIVKEKRFQSRAFLLLPMTFNIGVIVGPLLGGLLADPAGSYPQLFEPGSTLGGERGVRLFMEWPYALPNIVNAVFLCLSALGVMLGLEETLEGLRGKSDYGLRFSKWIAGVLFKTRTKQDYHLVDEHANSSDLEMDCVDKKEKPPPRQKLPLRRIWTKNVLCVLLAHGLLAMHVGTFSNIWFVFLSTPRFQPAGQHGSTSGDTLKLPKDYKPHLPFTFTGGLALPPPAIGTALAIMGVIGITLQLVLYPRLSFSLGTVTSYRLSAFFFPISYTLAPFLAIIPSTLAPPHQASGILVWSGLTIVLLIQVVARTFALPPTAILVNNASPHPSVLGTIHGIAQSVSSATRTIGPVLAGWIYGVGLNRGVVGLAWWCMAGVALLALIAGRFVQEGDGHEIWLPGEREDEDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5V3</accession>
    <name>A0A9Q8L5V3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Synaptobrevin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_01224</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755791.1">
        <property type="nucleotide sequence ID" value="XM_047900372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5V3"/>
    <dbReference type="GeneID" id="71981102"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01224"/>
    <dbReference type="OMA" id="VRKKMWW"/>
    <dbReference type="OrthoDB" id="190375at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15874">
        <property type="entry name" value="R-SNARE_Snc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005409">
        <property type="entry name" value="Synaptobrevin_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO11425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="117" mass="13142" checksum="6E72EB2226978A5F" modified="2023-09-13" version="1">MAAANNDSLYDPYVKRGAEEGTAGNARTQGLQSEIDGAVRTMQNNITKISERGERLDNLQDKTDHLSTQANSFRRGANRVRKQMWWKDMKMRMCIIVGIIILLVVIIVPSVVASQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5W4</accession>
    <name>A0A9Q8L5W4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_00534</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755788.1">
        <property type="nucleotide sequence ID" value="XM_047899682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5W4"/>
    <dbReference type="GeneID" id="71980412"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00534"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016078">
        <property type="term" value="P:tRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000015">
        <property type="entry name" value="3',5'-bisphosphate nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO11422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="405" mass="43481" checksum="22358CE3B2FE15C0" modified="2023-09-13" version="1">MVRRPTLTSAIFAISIVILAFSLFPTLLPRLRLLSSHFLPRQQQQHLTTMSTDYSKELNIALLAVQRASILAKTVFHQNSKGTLEKGDTSPVTIGDFGAQALIIAALQHNFPDDEIVAEEEAKDLRENSKLRDLVFGLVQDAKLHDTNAEKALGGPVASAEKMLDIIDKGDSKGGNKGRIWAIDPIDGTKGFLRGGQYAVCLGLMVDGDVKVGVLGCPNLPVSDSEPLKENIGADASDEEGKGVLFSAVQGEGAYSRPLQKGSLEAAKKIQMKPISNIADATFCESVEAAHSNQSDSGKIAEKLGITKPSVRMDSQAKYGSIARGAGDLYLRLSVKKDYVEKIWDHAAGDLIVREAGGQVTDVEGKRLNFSLGRTLKENKGVIAAPKDVHAKVIEAVQSVLSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5X2</accession>
    <name>A0A9Q8L5X2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755755.1">
        <property type="nucleotide sequence ID" value="XM_047901158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5X2"/>
    <dbReference type="GeneID" id="71981888"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02010"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040201526" evidence="1">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO11389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="27021" checksum="63804834371D2B7E" modified="2023-09-13" version="1">MLFPTIVPPLVLFLLTVVPVQANSYIVSLFTSHKNWITEASATVILPAVPHSVKGDASIWSGITMAGPNLTGDLLQGVSSNAPKTDTFCGRTIGGCSEYCGTRTDGWCGFAYTLLEDPDDAAIIGATMPDVKPGAEVRTHCYGQHGAIFDIAIECAMGDCAPVPAHTWTSISIVLDTADLSFKHHGPWGYNATGGEMSTEDGGKTWNIAKLHVPQQKPCIDKVTFKGRYCPDVEWPEHATVDMNVTEVPALSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6I6</accession>
    <name>A0A9Q8L6I6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Shelterin complex subunit TPP1/Est3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_02307</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756136.1">
        <property type="nucleotide sequence ID" value="XM_047901455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6I6"/>
    <dbReference type="GeneID" id="71982185"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02307"/>
    <dbReference type="OMA" id="DCVWHEL"/>
    <dbReference type="OrthoDB" id="3538943at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019437">
        <property type="entry name" value="TPP1/Est3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10341">
        <property type="entry name" value="TPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Shelterin complex subunit TPP1/Est3" evidence="7">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8L6R6_PASFU</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6S6</accession>
    <name>A0A9Q8L6S6_PASFU</name>
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        <submittedName>
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        </submittedName>
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    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO11883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6S6"/>
    <dbReference type="GeneID" id="71981211"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01333"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
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        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <location>
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            <end position="46"/>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO11883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="139" mass="15775" checksum="C9BFE09F1CB2B88D" modified="2023-09-13" version="1">MASAPVPNLENESPSTLERRNSLEKHLQARPTEQDLKDRHILLDTTAAPALQAKAAELERQRITDNLKKGLENRPEREELVERNVLPDSNAAPAIQGQQKELEKHMKADALDKKLQHRPEKEELIKEGILKDQDAVPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6V5</accession>
    <name>A0A9Q8L6V5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex II-specific subunit 65 IgD3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756227.1">
        <property type="nucleotide sequence ID" value="XM_047900270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6V5"/>
    <dbReference type="GeneID" id="71981000"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01122"/>
    <dbReference type="OMA" id="IFSWTVY"/>
    <dbReference type="OrthoDB" id="5345392at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055420">
        <property type="entry name" value="IgD3_Trs65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024662">
        <property type="entry name" value="Trs65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159:SF1">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12735">
        <property type="entry name" value="IgD3_Trs65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex II-specific subunit 65 IgD3" evidence="2">
        <location>
            <begin position="384"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="531" mass="57747" checksum="CC2DE2435C728A05" modified="2023-09-13" version="1">MADPDPTYFEALAKESHLDVLLPRSPDFDVVKLLRGGLPDDIFRAPARRNLFFDEQANIVLVLRTSEAQARLQETLPSLEIVLSAHATDAVPQGGGNAASASGKHDLDSKTLAADTYEQLVTVGDKAYVVWRPSLRLSRPRVRLHRPAIYFTANLTIANENTRGLQGAHPEYLKSFEPLPANVLEPLQFDPALKHTGLSLPESRITKVAPRAPRLHDAVKPIRGATRRAFPAVLALFTKIRYSSLPDAVVASLHLETSRIIAGVVTISRVAVEVSHAKVEHLTAFNLPLATQGGDETVVVYKIYRDTRHTAPINNTQSLSVTVTAKALLDQGSTIDFELNWQAQVNLSTPQARSEYHWSGPLSGMSAHQRGSSTQSGSGTISFEATQKSTADENAIMISISGPATVAKDSEFAIDLQCSNQSSRTRRFVVLVLQHRQPKTASSTQATAVDAGLVAKIFSVPPLESTKPLDVYVRSPEFRVGPLASGACFEAQLWFRTVSTGLLNLGTARILDLDTRQVINVRELPDIVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L727</accession>
    <name>A0A9Q8L727_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_01210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755774.1">
        <property type="nucleotide sequence ID" value="XM_047900358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L727"/>
    <dbReference type="GeneID" id="71981088"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01210"/>
    <dbReference type="OMA" id="AVYIQHQ"/>
    <dbReference type="OrthoDB" id="10062838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026505">
        <property type="entry name" value="Solute_c_fam_35_mem_F3/F4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346:SF4">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="59992" checksum="05254CEAC73B300A" modified="2023-09-13" version="1">MPKPQPAGAGSPIELSGSSLLCPDHFHARDNTSTPDPDSSDLVHLSKETSRQPTPLHNLPHPDRFPSETGIADDEDSDFDDWSNEGESSAWHDPASMPSDLRSERPSSFHKPCSHQSQPLLSGDKPPEYESPPRPGMGSRRSTRFRERDPPIKKPKSDTRTRYTYAACFLLVSLVSFAVQTETAVYIQHDLHWTKPYCMLYFTHGSWSLLWPVSLLILRLSKWSQPLDIFWRRHVALLRNTAQMIEHRTLHVPSHLQKKSPIPYFVRTTAFVTCALTVAGGSWYVAVDLTTASDLTAIYNCSAFFAYAFAVPILKEKLRLSKVVAVGVAILGVLVVAYGDQATAKHGSKSGGGAGGPSAPSDEEASNRAVGNLVIGIGSVLYGFYEVLYKKVACPPEHCDPKNGMVFANAFGSMIGVFTLLVLWIPLPILHFTGIEPFELPSGEASWMLAISVLSNATFSGSFLVLISLTSPVLSSVAALLTIFIVALCDQMLPPPLYSPLTAAALSGGLLIIFAFLLLTWSTYKEMEEENKKSAEDRVDESDVESVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7F6</accession>
    <name>A0A9Q8L7F6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucan 1,3-beta-glucosidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756613.1">
        <property type="nucleotide sequence ID" value="XM_047900975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7F6"/>
    <dbReference type="GeneID" id="71981705"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01827"/>
    <dbReference type="OMA" id="GWFFWTL"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046557">
        <property type="term" value="F:glucan endo-1,6-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000100">
        <property type="entry name" value="Glycoside hydrolase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF43">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="94"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO12247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="525" mass="58832" checksum="8DB1BF3015F3AE00" modified="2023-09-13" version="1">MKTFLNKAKAALDNSDSRTSSHSQTAGGPSSIQPPTLADVIRYRYHHGTNLGSIFVQERWLTGCMHDESFPGSSELTAVEGWVKMEGIDKARERFERHWHEYTSDADLDWLRDVGKCNAIRLPIGYFTLGPACCENTPFQAVGAVYQHAWQAVKDLIQRCGSRGISVLIDLHALPGGANGGDHSGTNSGKAEFWHSRKCKSLATRCLCFIAQQVRDMPAVSGIQIVNEAEWDANGMYEWYCDVLTELSTIDCTMPIYISDGWDLTRCAGSIQGKNTMISKHANPIVIDTHLYWCFSDGDQQKSPQQITGEVGSKLHENELKCGSVVDRGASQAVVGEYSCVLGDASWAKGGCDPKEQLVRGFGNAQSQRYQQRAGGSYFWTYKMDWMPGGEWGFRQMTEQHAITPPTSLTLEIHDLQTRISQAQSQRDYLRGSSWGSHCQYWDSNHPGVYEHDRFVQGWDVGFSDAMVFFGMRSQHHLCGADKIGMRDLWVLKRLRESGQAGEFVWEYEQGLRQGIRDFYQAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7I1</accession>
    <name>A0A9Q8L7I1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hit family protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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            <begin position="131"/>
            <end position="141"/>
        </location>
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    </evidence>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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    </dbReference>
    <dbReference type="RefSeq" id="XP_047757451.1">
        <property type="nucleotide sequence ID" value="XM_047902312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8X1"/>
    <dbReference type="GeneID" id="71983042"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03164"/>
    <dbReference type="OrthoDB" id="424551at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO13085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="179" mass="19941" checksum="746FF044010DCC62" modified="2023-09-13" version="1">MDHATRFATTNDAEAIIDLSKRVQAALIATGSLQEVGPLDEESVNDAIEKQRSFVLDTPDISYERCIIGCAFFKPVGQDCFVTTSTFTMNDYQKPLLFLYWVMLEPSQGIGSSFIEEVLNGMRSNGHNNGTPLLLDCWAGNTKLRTFYTHLDLTFAAIVPQEDYEIGVFYLDLADLHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L959</accession>
    <name>A0A9Q8L959_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heat shock protein hsp88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02724</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757498.1">
        <property type="nucleotide sequence ID" value="XM_047901872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L959"/>
    <dbReference type="GeneID" id="71982602"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02724"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000011">
        <property type="entry name" value="Heat shock protein hsp88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="534"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="717"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="630"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="720"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="793" mass="88398" checksum="F5C1E899C4D56756" modified="2023-09-13" version="1">MSVVGLDLGTQNSVIAVARNKGVDVITNEVSNRATPSLVGFGPKARYLGESAKTQEVSNLKNTVGSLTRLAGRSLQDPDVQIEQEFVSAPLCEVNGQVGAEVTYMGEKQKFSATQLIAMFLTKIRDTASKELRLPVNDMVISVPAWYTDAQRRGLLDAAEVAGLKVLRLINETTATALGYGITKLDLPTAEEKPRRTAFIDIGASNYTATIAEFRKGELKIISTAYDRHFGGRNFDKAIVDHFRDEFKERNRIDIYENPKARVRVAAAVEKLKKVLSANAMAPINIESLMNDVDVRGMLKREEMEELPGVKALLQRATVPLEQALADAKLKAEDIDFVELVGGCTRVPALKAAIQNFFGKPLNYTMNADEAIARGCAFSCAILSPVFRVRDFSVQDVVNYPIEFAWEKSPDIPDEDTNLTVFNRGNAMPSTKILTFYRKQPFELEAKYAKPEQLPGKINPWIGRFSVKGVKAEGKEDFMICKLKARLNLHGVLNVEQGYYVEEQEIEEPITEEKKDGDVSTIQHLNSVRPAFISSEEEERSLECTATDLRNLRSSPEQDRAAKRSKPNEPLLTNRQAMDTDDKANGEAKAPVKTRKVKKQVRKGDLPLSAGTASLDQAAKDNYMEKEGQMVSEDKLVAETEDKKNELESEIYAMRAKIEEPYESNGYSDFASDEEKEKIRAKCEELEDWLYDDGEDAKKAQYVAKLDELRASAGPVIQRFNDKRQEEEDARRRIAEEAAAKKRAEEEAAKKAAEEKRKAEEAAKIMNDGSDAAPQKPDEEMKDADQPAEVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L9I1</accession>
    <name>A0A9Q8L9I1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRP9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757766.1">
        <property type="nucleotide sequence ID" value="XM_047901959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L9I1"/>
    <dbReference type="GeneID" id="71982689"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02811"/>
    <dbReference type="OMA" id="YETNKGA"/>
    <dbReference type="OrthoDB" id="5419752at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP9" evidence="2">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="162" mass="17829" checksum="3E26D0190521564E" modified="2023-09-13" version="1">MVNLNTSDEWQHQTSLLLQARPTTTRITTKYKIPHLSAPKYQQKLLKRKRDGDGEQDEKDGGAATHIPRATLTLKTYDPESGVVLKFKTDRAAEVGRLIHGLGRVGRHMAALPEKAEDIPMEDAPVIQKAAEVVSSVKDAITGDPQPQQSAGGSKKKKKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBP5</accession>
    <name>A0A9Q8LBP5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758848.1">
        <property type="nucleotide sequence ID" value="XM_047901825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBP5"/>
    <dbReference type="GeneID" id="71982555"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02677"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040515218" evidence="1">
        <location>
            <begin position="17"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="125" mass="14220" checksum="13BD92ED133CD03A" modified="2023-09-13" version="1">MALLSLWLIILCLVSAVFPWSAPSDVKVEDVAFKDYHDLWHGYRKSPILAPHLEIRNMAQHGNEHTKRWYGMEQLGSGATQASGNVQPWPVTCTTPEIIQTLKYCYVDERSHKNLEKIIAQSTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCF7</accession>
    <name>A0A9Q8LCF7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aquaporin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08471</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759190.1">
        <property type="nucleotide sequence ID" value="XM_047907619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCF7"/>
    <dbReference type="GeneID" id="71988349"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08471"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF283">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="260" mass="27656" checksum="2713D7818F6ED0EB" modified="2023-09-13" version="1">MGPPRFDQPFAGYAQPRDPGSQNAARNHFIAATGEFVGTFMFLLFAFLGHTMAVDQAPDTAPNGANSSMTVIYIAMAYGFSLLVTAWTMFRVSGGLFNPAVTIGLSLSGQLPWTRALIFLPTQLLAAICAAAVCSGIIPGDIATVQTTLASNVGIAQGLFLEMFLTAELTSRTYIAPVGIGLALFVAEIAGVYYTGGALNPARSFGPCVAGASFQEHHWIYWVGPYLGAMIAAGYYHFVKFFNYEEANPGQDSADGKHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCY5</accession>
    <name>A0A9Q8LCY5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759566.1">
        <property type="nucleotide sequence ID" value="XM_047907765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCY5"/>
    <dbReference type="GeneID" id="71988495"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08617"/>
    <dbReference type="OMA" id="WGNELIP"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO15200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="210" mass="22966" checksum="51A2FEC7C179D9DE" modified="2023-09-13" version="1">MCQLDSVTWSSAGGSSPVDSGYVSAVVNDELEVMWPSESSSLPTLSRETSSFGTDFSSPFTSGVWPVEPLFDTFAWGNELIPEPNPHSGWWPLFQPVEEGYLPWSDTYNPFDTSYGSLGHSANQPQPIYDPRALSPSVQTAQLAADLLQLDAAINPADIELPSTKKVGISRTTVRSKERKGHECPDCGKSCVRPSDLLRHKQDIHALAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LCZ5</accession>
    <name>A0A9Q8LCZ5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_08555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759315.1">
        <property type="nucleotide sequence ID" value="XM_047907703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LCZ5"/>
    <dbReference type="GeneID" id="71988433"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08555"/>
    <dbReference type="OrthoDB" id="5421637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040172783" evidence="2">
        <location>
            <begin position="19"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="248" mass="25061" checksum="42CF8D94E7748ADA" modified="2023-09-13" version="1">MKSFTFTSFAVAATLAAAQDVTVSTTCGDYTAGSDEVLYTVPYTYEEVIPIIENFGNLTYAGVPDGSVSLNGSDNTVGTARTYELAGMKAVETLLNYSNPAAPGPYFENHNFANATVGDASVYIPTDATSLTSVCDGKASMMNFTAHFCATNATFAAATLHMIHLGWAANVGTMLGGKNFTDCAALGASNTSGPASPTGTAPSGSTPSGSSGSDAAAQTTAAGTNAGSRSQAGWRSAGMGVAFALLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEQ9</accession>
    <name>A0A9Q8LEQ9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760419.1">
        <property type="nucleotide sequence ID" value="XM_047904139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEQ9"/>
    <dbReference type="GeneID" id="71984869"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04991"/>
    <dbReference type="OMA" id="RECITCE"/>
    <dbReference type="OrthoDB" id="10647296at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="537" mass="60391" checksum="762F14F29E387607" modified="2023-09-13" version="1">MPKGKLKVPKGSNKSMMKKERKLLAFLQQDGQLRSDAELHDLLRWGNTHGFNTRLELRQLINGNLPQGTSGRCLDDLRLKPVYSERVLLDHLRSTWRLPANANRQSLLEWGQLNGRTTWQSLRQLGNNIVRGDSSLPPPPPAKRAPAANTLPSASAAGSLAQHKLRSKITVLAHQACDLIDCENSDAAAMNWTKMASDMTPSDLAILTHLQLIGQLPLQANLQSLLALGRECEFSRNALREAGNEIRFGEPCESQEAYRERLGYLARQGVECMRSALQNETPGVDGKRIAAIEFINRFKLDEQEPGQHLWRQTSTRDEDLVDYKYPSAFTTARLDNANQSRSRPLDAPASPLMTEPWMSPRQEPLLQPDMSLHAAGDQMINDQPASRSTAQHAWPEHMKTLAQSFDETDQDEQTLEERENRGFTVDDLTNFDAVQTKRFSDLHELDPMRRHGQQQALSCFTTAGIAKHKRSSLFALPDDRNRDGWHVDAGDTSVFENNLASELENGVFVQYDRELDLPARLHVTNGKLLDDMDIDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGK2</accession>
    <name>A0A9Q8LGK2_PASFU</name>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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    </dbReference>
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    <dbReference type="GeneID" id="71984577"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="UJO17013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="134" mass="15028" checksum="F8398EA3D0FF8CFE" modified="2023-09-13" version="1">MIPTMRAVILLFWPDPPRSTKITERAALVLTGDSTLLKSGPVARQALSEHSLPGYDNCDRIVHIPMPKAVEFLIQPDKRAVAANPALQARNGHYAAQNRAECLLEARERVRLAKEGRIGKKAKSYVEFERRVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGP1</accession>
    <name>A0A9Q8LGP1_PASFU</name>
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        </submittedName>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71983774"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03896"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="77" mass="9133" checksum="4B15ECC1AA634B0D" modified="2023-09-13" version="1">MYALTDPGCALRRWIVDEFVWEHDADSEDPLDFEEFKELNPEFLLDVVREQGRRLGGAVDERELHRKPADDPEKYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH42</accession>
    <name>A0A9Q8LH42_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="32672" checksum="AD47B1AA0F5BF123" modified="2023-09-13" version="1">MTLPQRFWQYARPVTVAFLLAAVLYSALVVKQPAATTNRLHSRQLGLYTHTNASYARDLGHSQYLYTRDTDYTGWPALTAASDDDYAVAKKRGELLLCWLDNPEEVPPEKGTSPWNNYDDLETWGWEDKSRDWTGGERDPGLKDIFDNSEINRDAKGDKKAVFEHTREHPAEGGQRYPATGAKYENYVYPRHGLLVAEYNYGPDRRIESLIRKGTWDTSTMSKPKLFQLSDVMWLGWAKYTTDDNRSNLQIMAVHQVGNDPTKAMMAKIMKATVPSKGPMFLGRAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHC6</accession>
    <name>A0A9Q8LHC6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">CLAFUR5_05450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
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            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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        </location>
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        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
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        <location>
            <begin position="1"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="182" mass="21220" checksum="C78A0B6A79F6F59E" modified="2023-09-13" version="1">MGLLDSFFGSSSRRSNREWYGRSSNHGSSSRQGYSSYEPSSSSRQHSSNPYSGGSSRRYREGISEPYYNYTRDDRRYSFGRREARNEQVHFRRPEVDHRDFYGGRVPETARAHYSRDPYSSRHPKPYHADPHRTAQREHERNYHYGVGGYGSSSRGHGGGFGYQDRSAASYLEMDGRYPRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI2</accession>
    <name>A0A9Q8LHI2_PASFU</name>
    <protein>
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            <fullName evidence="4">Amine oxidase</fullName>
            <ecNumber evidence="4">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_06174</name>
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="4"/>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762102.1">
        <property type="nucleotide sequence ID" value="XM_047905322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHI2"/>
    <dbReference type="GeneID" id="71986052"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06174"/>
    <dbReference type="OMA" id="DVGCGWL"/>
    <dbReference type="OrthoDB" id="3646831at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF313">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040413660" description="Amine oxidase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="6">
        <location>
            <begin position="39"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO17736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="539" mass="59371" checksum="03A05755D3A774E9" modified="2023-09-13" version="1">MKTLLTALFATQCLAYVAKPHQYEAACRKTTVAILGAGMAGISAAQALANASITDFVIIEYQDRIGGRVHAVDFGKKADQSPYKVELGANWVHGTEGIAINPIWTLAQKYDLKHGIQNFSNILNYNETGLIDITYLYEEFEEAAEQAAINAGALLEGNHPDQTARANLALAGWRPDVDDAAAGLVEWFGWDFNDGVAPEVDSATFGFTAENLTYGLFGDSEALIVDSRGYSAIISGEASTFLQENDPRLLLNTIVTNISHSEDRVTVYSDDGSCISAAYAITTFSLGVLQHDSLHFAPALPEWKETAIQSFGMATYTKIFLQFNTTWWPSDVEFFGYASPTTRGYYPMFQSLDVPGFLEDSHMMFMTVTEHQAYRAERQTDEETKAEIMEVLREMFPAIEVPDPVDFMYPRWTLEPWARGSYSYWPPTVGLQMHQNLRANVGRLFFAGEHISGQFYGYLHGSYFSGREMGERVAGLLGGKCRGSAGEPDAEACGELVRYEVLSGVTPKDEYDTENGWPVTSVAIEVMEGGDALGNPLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHI7</accession>
    <name>A0A9Q8LHI7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047905442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHI7"/>
    <dbReference type="GeneID" id="71986172"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06294"/>
    <dbReference type="OrthoDB" id="3189033at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="497" mass="57006" checksum="18E78F15DA4D4907" modified="2023-09-13" version="1">MKQRYYSNMSDENLQPPTMNGTVEIADYRPPLPPRTPLSPPDEAEEHTATENPENVKRTSYFPLQPVAEQPVDTKEGSQGLNDQNTPIRKPPSQHQASHEHRTEDQNQTQPREGPKGLNGQLIDTSHLPPPQRQSHLSEQTRESYSPTSWHRSLTILTAFLVPYPKPQLPPVSVHTTSQLIPPRFMIYTPPPAPFLTKPEGESKTDAWRKEGIPHFCRRKWYEELREAKMRQPKDGNTTKWKRAKWRATKGTDWGIDKTKSTNLEFLNRVARLQDESNAAAEDVYAKQVSPEELVLLHPPVLRLTIDGSHDHDEELLRENFTASLLRTKKRALRDTIISALLFPPAIVIDTVAVPIWPFGGLAEIDAVWFYASYRGAKTSSDITKRLSSTAYKYKHLNLTLTPFAKMDILERYLAARCHDADPKLFPEYVATPADTEVLKAIGWTHSVPEGEMEWEDRQWEARQVRDDLERCFGKAAREWAGFCKRWVKDPEKAMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHQ6</accession>
    <name>A0A9Q8LHQ6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose N-acetyltransferase 1</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_05848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761979.1">
        <property type="nucleotide sequence ID" value="XM_047904996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHQ6"/>
    <dbReference type="GeneID" id="71985726"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05848"/>
    <dbReference type="OMA" id="DWSRLGY"/>
    <dbReference type="OrthoDB" id="5367275at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="43336" checksum="25C9B343BC5E49DD" modified="2023-09-13" version="1">MPSRLLLSQSQVSVVVSSTVVVVFTLLLFLAGYSIQQREVQGLKIAIQPRIPKAPQSLATSEDTTQQHFEPSRLFGKRDGRIAYTDFDRHVHSSGAGANINWQRLAHVQLVRRHHDVCSAIMVLAELHRMRSPAKRVLLFPKAWAEEKKAGKGDISDPYLDSTRRLMKLAARRYHVNLQPIDPIRTSDDGDTYSLASAYALTHDFDRLLTIETPGLLLDAEPLDAILGFSEKAPFVMLHDTNTKDGVHSEDLFLLEPSKSRHAELTKRLVTPEMSQYNDTHLSTLLTEAILLASSNEDTALIRSVGALHDVGPDFNKTSFMSDVAYIRFSDPKLPGPEYEVPWADKVAARPKNKDADWAWTSLYGDFAQKRMEICGLDLETWRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHU5</accession>
    <name>A0A9Q8LHU5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762100.1">
        <property type="nucleotide sequence ID" value="XM_047905575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHU5"/>
    <dbReference type="GeneID" id="71986305"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06427"/>
    <dbReference type="OMA" id="EDIPTPW"/>
    <dbReference type="OrthoDB" id="3625729at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="293" mass="33874" checksum="B5066D8F30431BB3" modified="2023-09-13" version="1">MPSNLLSYSASFNQQSAKKDAQQHQSWDRRFAWDFYDPIMDPFDDNIDSFEVPPSYDSLRRGTTTHKTPSDLALIPADRFFAEPCLPPVLNYFVRVEDIPTPWKLLTGPSMTNATLHHNPDPLRKKRYRVIYPPQYEDVYLHKTTWAANTDSLPRYYVELLGNTRYEPEPIAILGPTDHDDSLTNEAKNVAIAHAPKVLSRVEDSVTQTRRFAVFCEMEYFSWDWDCKTAAAKGDMKALIGKAKKQCCRTVRLVEKLEKYLEYVGKKEEYAKVVRDMGKSILEANIRLARLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIB7</accession>
    <name>A0A9Q8LIB7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762279.1">
        <property type="nucleotide sequence ID" value="XM_047905109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIB7"/>
    <dbReference type="GeneID" id="71985839"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05961"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="148" mass="16287" checksum="F075662019D8E953" modified="2023-09-13" version="1">MMKDYLTQLYAIGLFTFSKKKVRYQRSSPQSRTLSIMGATCGADSKGTIIKVAVIAATLAIVVIGLAIVLWRWREAVEKRQIKAAEESGTPIFEQNGFVFAKKLKNPSEFDLESQDLQSNSTDSPTIPLVNLRPPIPALIRTPATGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIJ5</accession>
    <name>A0A9Q8LIJ5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
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    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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            <begin position="17"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="482" mass="53101" checksum="4AA4AF1BA86A8D83" modified="2023-09-13" version="1">MLKQAPMAATRMKYTPKKLLVCCDGTWRNSDSGIFKGTGLAWLWSGQEQVNTNVTRISRAIRSTDTQGKQQIVYYQAGVGSEGNLIERLVGGALGVGLAANIREAYSFIANNYVTGDEIFLIGFSRGAFTARSIGGLISDLGLLTTDGMDNLVGIFEDWEHAGNDGYKTLLAKDDTAFAVKSSMADPKAYVLEYRQGLLQRGYTRDETIPIKAIGVWDTVGSLGIPVNPLLQRIGFPTVLREYRLYNTDLGTNVENAFQALALDEARAAYRPALWQKLPGSTSDLKQTWFPGAHTNIGGGYPDSGLSDTTLAWMMSNLSPLIDFAPEYIKKEHGKHERYLGQKNVPPTGPKWAASQLKNTSSGLRALLGIVSRQPGRYHVLNKKTLTVLHDKPLLNTNEHIHVAVRSREKTGGLNERNKVVEYKPKALKKGEYELVDATAEPGKASWRYVGKEKSFKGEMLPEDALGVFEKEIFQDYVTGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ13</accession>
    <name>A0A9Q8LJ13_PASFU</name>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="216" mass="22908" checksum="720896A3D7E28F86" modified="2023-09-13" version="1">MPKKLRKNEIDVTSSASSAILTPLFTPTIEAANDSAGRSNTSAIGESNAGGIPFPSYRSKLTKPTKGLMSKALCTVEDKIEATMDEVGAIKLDMLGLTAQLYQVQTMQAIADIWLEEKLRELKAGPMGKKVSSKKVSSKEGTVLKTTASAAKKEDGVKFFDRSGVPLKLAGVVAFAAWVGSTEGMEVYGVVLTVGLAAVVLSILVSEEMAVHEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LJ31</accession>
    <name>A0A9Q8LJ31_PASFU</name>
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        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
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            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LK50</accession>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="GeneID" id="71985481"/>
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    <dbReference type="OMA" id="CPQAYGE"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="113" mass="12662" checksum="90C1497065AA7108" modified="2023-09-13" version="1">MSQGSPVDSVISNTSAGSKLPENTSTTEKLLEWYSVDILDNFNKRDFDYPIARYGSENYKFEAIQNDGSLLELDAPGMKKLRVWFFLEHCPQAYGEVLDVVVHLDEINGTAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LK76</accession>
    <name>A0A9Q8LK76_PASFU</name>
    <protein>
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    <organism evidence="8 9">
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="UJO18233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762599.1">
        <property type="nucleotide sequence ID" value="XM_047905140.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71985870"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05992"/>
    <dbReference type="OMA" id="KVNDHIG"/>
    <dbReference type="OrthoDB" id="27603at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008467">
        <property type="entry name" value="Dynein1_light_intermed_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688:SF0">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="4" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="353"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="528"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
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        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
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        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="443"/>
            <end position="472"/>
        </location>
    </feature>
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        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
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        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
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            <end position="562"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
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        </source>
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    </evidence>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO18233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="614" mass="67681" checksum="455B8B3DCA2EDB0F" modified="2023-09-13" version="1">MATVTTTRQPTTRRKKDQRSDIWSNLLRQTREAQARSRTQAVQHRELIVCGASPDDQRQLLQAITRPPPPQPPSRGNERRQQRPRGDLRLSNKYAYGYGHVTLYSPPQQSGSGIAALGSDAEEVARIELHTIPEAKDEYVATLRGLLQKPREAPNDHVEDQEAGSHVPQKPSVCLLLSWREPWKFLEQLRRWIQVLAKALLPEGQKATDPMDVVKDADIFISVVVQHTEAQEDLLKEGYKEDDFDYISQCLRSAILPLHPLSALVYTNTNTPPQQPGSALSEPQKVLCTSLNLDLVALSPKQQRSGDTPQKQELGPRHDFMDRMAIVIPAGWDSIAFIRTLSETFSPEDVLHGWYTDLQPSPDPTPQPSRKHSDDAKAEGQDSAQSNGGAEVYESSPVDGDDDELAETPLSPSKAPQSAVKKYESRILDPQAHKQQPPPRIEVTTKPDQEFLAEMRQHLQQLELKDQERDNNGRSAGVSNTGHSTGRNIGMPSGEQTGALNELGDVSFNVGGVSYDTISAEAAIERLKRPAQTLGSPISTIPRTGTPKPPRTNRETSDDVRGSETFTPVGRARDTSSAKSPDFDPNKLNDFFNSLAKKAGGGAGTRDNTPSKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2Q3</accession>
    <name>A0A9Q8P2Q3_PASFU</name>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2Q3"/>
    <dbReference type="GeneID" id="71980164"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00286"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="66" mass="7010" checksum="020EEA441876089C" modified="2023-09-13" version="1">MKDGGVGVGEFVILEASYETKRITKYVPSEAHLGAFAVTSGLWTGGTADAMDEQLDLQVQIAGNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P372</accession>
    <name>A0A9Q8P372_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899196.1"/>
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    <dbReference type="KEGG" id="ffu:CLAFUR5_00048"/>
    <dbReference type="OMA" id="WIHIWIA"/>
    <dbReference type="OrthoDB" id="5397827at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="265" mass="30318" checksum="A6279E6EF04FAC28" modified="2023-09-13" version="1">MASLRLTIPRAGFQLHAKQLQQRLIIPSIRHASTTPPPKPRVLAQPDKFRPPSHPSRLRSKTPRYQYGADLTEEQKTKKQYPHMMPPEGSIMHWFLTNRSIHLWISLSILVSLVFGVWFSEFIHNTPYRDLLPPNSMFLSHPFSFLGRYAEVYQMHVAYVSAQTAERRKQKVDDVKKRSDYRKAHGLDQDEGIFGGWTAKEDDEVKGPGFKQEGVQMEQAGPEAAMEVVKGTGDGVVGRAGEAEETYVDFEGKTQPLRKKWFGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P440</accession>
    <name>A0A9Q8P440_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Metabolite transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_02006</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756949.1">
        <property type="nucleotide sequence ID" value="XM_047901154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P440"/>
    <dbReference type="GeneID" id="71981884"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02006"/>
    <dbReference type="OMA" id="CAAITQG"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="571"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
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        <location>
            <begin position="134"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="706" mass="78990" checksum="5EF4CB62FDD587E9" modified="2023-09-13" version="1">MAAPNVDNQQQAVPEIEVTRVRRRTATHDDSSSYDDDSMLDAPEDENIFDDNDQCLVDNPLIRLRPDEVERKAKRFVRTHGLHNQEETFIKAGKILRDPEAWEAVPNLSLDEKEVLFNETRGGFWKQPKELRVTIITLCVAAVVQGWNQTASNGANLNWPKQLGLLAFDGCDPIGRDAWIFAIVNAVPYLSASLIGCWLSDPFNEYFFGRRPAIAFSGVLILASMIGSACSQTWRQLLACRAILGIGMGCKASVVPVFAAEVSPAHIRGSLVMNWQLFDALGIFLGFTANLMVSQVGDTAWRWQTASSVLPTIVLLTLIFVCSDSPRFLMKRGPSHYLEAYATLLALRGHPVLAAKELLYVHCQMEVEKRFISGKMSDAELVHREEQVVEETKGNASHSKLRARFQPARSINYWQKLGQLFTIKRIRRAMLAAVVVMVSQQLCGVNVLALYSSNFFCEEEASDKIGDLADPSYLQPLFLSWGIGLVNFLFAFPAYYLIDKRGRRWLLLVALPFMALSMLGASLAFLIPAGSPAHAPVIGVLVYIFMVFYSPSMGPVPFTFSAEVFPMDHRVVGMSFAVFTNMLGLGLLTLFVPIITVKVSHAGLLGIFAGLNVVAFVLIFFFVRETAGATLGRTAGSMHFMSLEELNYVFGVSTKKHAIYQYRTVLPWIWRYYVRRDKGCPDSPEQLYRWATARQQGQHEQQNRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P461</accession>
    <name>A0A9Q8P461_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="1" type="ORF">CLAFUR5_00156</name>
    </gene>
    <organism evidence="1 2">
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        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="1" key="1">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48119" checksum="B46692B09815DFF2" modified="2023-09-13" version="1">MPKPVSSTAEERGKGVEVKVKKMDGHVEDHGKHSTISAFAKHLRSTGQQLLQNVADGAGDVLIEMKGQVFDLTLLAKAQYTGTRHGLCSACSSMPFGQFQPGVVSILAAPSTDILHPLHKMSKHESSCRFCGLVCQALDREVNNPWDLLGEKRKMSHTSSMHRVESELPDINNATAAEPSTTAAVRDEERPRTLSQLDHELVANVAFLVRLQRHRVLGWVWIDIKNPNHKDSGLVIIEVWGFGRNTRTEMSRISHFQLRVSSTSTIAQEGPSLRYANRLNTKRVDLSAMKFSLSHCQEEHDKDGDECSAPLYTRRPRKGLAPGIRLIDVKHLQIVEHPHPQAQYACLSYTWGGFEALTLERANLAKFTMPGGLDADRAHLPRTLRAAIEITKDLGWGIFGLMRYASVSMTMQRTNSIRSGKWIRYMAMQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4A3</accession>
    <name>A0A9Q8P4A3_PASFU</name>
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        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_00400</name>
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    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Mycosphaerellaceae</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4A3"/>
    <dbReference type="GeneID" id="71980278"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00400"/>
    <dbReference type="OrthoDB" id="2316594at2759"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
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        <location>
            <begin position="57"/>
            <end position="112"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="57751" checksum="BE8FE4C0DBB54F7C" modified="2023-09-13" version="1">MEANAQDHSSAPTYEDEKASYQEYLSTAGTGRHGRQEELRTTPLFSLAVKHTIDGNLGHGVTARRRSSSTTGSDDFRDASDEPSDIEVQAAPECPNQPHDESESIDDPQPPVLPQYALIGHHVGEDATIGKNEPILLNVNAPSSTFICGSQGSGKSYTLASMLENVLLPTTKLGKVTEPVAGVVFHYDVDSTNSIAEAAYLCSRGIKVNVFVSQSNATALTKAYKAIDKDGNITVQPLLLRSSDLSIERMHKLMAVANKEGPMPLYMEVVQRILREMAISDTFSYANFKAKLDAEKLTKDQTGPMSLRLGLLESFMAVQDRGELPSRQHTNHPKQSLFDLSPGTLTIIDLSDTFIDSSTVCILFDVCLGLIKEQRPPSGLVISLDEAHKYMNKTAAADTFTERLLTTIREQRHNAARVIIATQEPTISERLLDLCSISIVHRFTSPAWFLSIKDHLSGASKLVTSSEEQHAMFERIVDLHVGECLVFSPSSFVRMEDGKVKKLGAVAMKMKSRKRLGEDGGMSVLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4T7</accession>
    <name>A0A9Q8P4T7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin-related trafficking adapter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757791.1">
        <property type="nucleotide sequence ID" value="XM_047902354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4T7"/>
    <dbReference type="GeneID" id="71983084"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03206"/>
    <dbReference type="OrthoDB" id="2238745at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF174">
        <property type="entry name" value="ARRESTIN-RELATED TRAFFICKING ADAPTER 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="453"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="845" mass="92950" checksum="361E3C59C6324B46" modified="2023-09-13" version="1">MAVSYRSSTYGLLYYEPATHHNVDERPQKLFRPRRVGPGRVCIKSVGPDLESTKNDRPQVPYPFKERRKPSVHVKLAAVTRENAKRFLRSVIASPNSNSDSTKLPSTDKADKRRSWSPTKRSQSVQSGDSGAAAGNNMRGNIRHSIGGPINAHLARPRLQSDARDRSAFPSQSTLSSTGARSSPRIDTSTVDSVIPNLNLNDEKPIASGNGVSLGVHLAEPVLFLQGFENAEHATGNTAMLRGSLHLRVQKSAKIKAVNLKFKGTAVTKWPEGIPPRKVEFEERDTIMSHTWPFFNAQFESAEKGTNADHVQLFKDGASATVTRLDPLGRSNDAGSNLNLSAKEAKKLALSVNQSRSFGKGDPVPGGPTVAAKGYRTFMPGDYIYNFELPLDSRLPETIDVELGSVKYELEATVERSGAFRANLIGNKEVTLIRAPAEGSLEQVEPIAISRNWEDLLHYDIVISGKSFPLGSSVPIAFKLTPLAKVQCHRIKVLVTENIEYFCSNKRVHRMEPTRKVQLFEKRADGPPNSTYPGSTMRVTAGGGIPYDQRARAARGEDVASTDSTNLLGNLEGDSNIGPTEMEFNVQLPSCHTMKDRERNQKLHFDTTYQNIQVHHWIKIVMRLSRPDAQDPSKRRHFEISIDSPFHILSCRATQANISLPAYSSPMATPMSAHLFECGCPGAAQRRNSPTGLIPAMHAINTGSRTNVQDARPAHTDPWLPQLQRPPTLHHADHVRHDQHTLSRLQRAPDRPMHLLRAPSFNPPAFEDEEPPPPLITPPPQYDSIASPTSGLADYFARLGDAYDSDSGDESHTTGGRVNVPLTPGGRVNRSMDLGRGWVPVGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P563</accession>
    <name>A0A9Q8P563_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Meiotic coiled-coil protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757955.1">
        <property type="nucleotide sequence ID" value="XM_047902425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P563"/>
    <dbReference type="GeneID" id="71983155"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03277"/>
    <dbReference type="OMA" id="ANERMSQ"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="269"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="332"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="368"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="560"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO13589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="678" mass="75591" checksum="C7E7353107E7191B" modified="2023-09-13" version="1">MEWTGSPTKKASASFSIYDENTHSQMGLKRTSSALPLPLTTAKFVNRMGPPPKHHNMPGPVDELLAKLTNQQELLARQKRELEDAENRSSHSSATDPNANTPPTDSFSSDGRPDAAEVMRLKKELALANERMSQMDLQITQSRIVQHTMEEAIGSPFPTAQHLAASMPVHNMMSAAQSNPYARVDSPFERGSFNMPQQQQSFDSMQGLSRQYGGYNNQPKYTPPITPAPFQAPYAMPNGVGNHQLPPVGTKLSPTAAEFGVGRGQWSMQAPPAYASATEPLNYRRLLDRNMSCNWKYIVDKIVCNNDQQASIFLQQKLKVGTADQKFEIVQAIIDQAYPLMVNRFGNFLVQRCFEHGTPEQIISIAQSIRGNTLNLSMDAFGCHVVQKAFDCVPEEYKAIMIHELLRRIPETVIHRYACHVWQKLFELRWSDSPPQIMKYVNEALHGMWHEVALGETGSLVVQNIFENCLEEDKRPCIDEVLASIDVVAHGQFGNWCIQHICEHGSIPDRTRATEHVLRYATEYSMDQFASKVVEKCLKIGGGDFLDRYLDRVCEARPDRPRIPLIDISGDQFGNYLIQYILTNGDPERREIVAAQIRKHMVSLRGSKYGSRVAMLCCNPAFTTRPGPPAGLPLARNNSGGGFGGERFGGDYNRSFQGPSDRGYGGMGRGGYGGGAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5N1</accession>
    <name>A0A9Q8P5N1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-2,3-butanediol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_02612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758661.1">
        <property type="nucleotide sequence ID" value="XM_047901760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5N1"/>
    <dbReference type="GeneID" id="71982490"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02612"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF121">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="27917" checksum="3BD66F4B80BA382C" modified="2023-09-13" version="1">MSKVAIVTGSSRGIGRAIAIRIAQDGYDVCVNDIEANKQGCEEVAQEIQKMGRKSCVATADVSKLSEVEAMIQTAVKELGNLNTMIANAGIAQVKPLLELTEDDFKRMFEVNVYGVHNCYQAAAKQLIKQGNCTPSNMGKLIGCASIVAFKPFVLLSHYSASKWAVRGLSQAYAMEMAEYNITVNAYAPGIVGTAMWDLIDEKLGEKDGRKKGDTIKKYTEELIAQKRTSVPEDVAKLVSFLAGPDSDHVVDGGIIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5P2</accession>
    <name>A0A9Q8P5P2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional activator ARO80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_03082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758706.1">
        <property type="nucleotide sequence ID" value="XM_047902230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5P2"/>
    <dbReference type="GeneID" id="71982960"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03082"/>
    <dbReference type="OMA" id="DWHPRNL"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000012">
        <property type="entry name" value="C6 transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052780">
        <property type="entry name" value="AAA_Catabolism_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31644:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR ARO80-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="813"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO14340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="981" mass="108694" checksum="07618225D22E7A16" modified="2023-09-13" version="1">MAANGYGQRQASGGDLQYRATSQSPPQQDNKPNNQAVHQRTYQACIPCRQRKVRCDLGSVDNPHDPPCTRCRREAKECYFSATRRKKKNDSGNNTGSDAGEDAAYDARHARKRVRTSAPPESEYGTDAVDDRPRTPGGSIARSQPLPRPQPPRPVHYDEEQVKKADETAAMIQHAPLHGGHDALNLLYRAAVHPRTASTTSSHGRPSLNAQTSAGLPSAFSPIMNKVGTGSLSYANGPMGMFQGDSSIWKVQTDGPDTKNGVTDNINSDGHKSAIRAWSRFKFVRAGWFTSKEGIDYIVYFYKHLGPLTPVVLPDFRHASTHQRLLEEEPMLAVTMLLIASRHMDLEGPGSNSRPMHIHNKLWTYLSGMIDRVVWGQEQFGGGFCGAGAQPSCDVHPLTRKGLRTLGSIESLILLTEWHPRAMHFPPDEDDDDLMMPDQSFPTPAFEAEDVPKGIGGHRMDAWLEPCWRSDRMCWMLLGMAMSLAMEIGVFDSTESHRHARSADGGPLSVEDLAAYDKRRNNVRDLLLIYVTQTSGRLGLTSMLPTYYSKPEDSGLFKKQVGQQDSVQDITLHFWLRMAALMRDGNQKIFANRNFTRDLIRNGTYKTALDGLQKPLTEWLEEFQDCNAIPKHMKSILTIEYEYCRVYLNALGLQAVAERCANDQPSPPTILDPPLEMARTAFAANGTKHDAIAPHTLSKWLGGDRHYLQTVGDAARNLLKVVVEDLYPDGFLKHAPVRTYFRIISVAIMLLKSFSMGATESDISDSLSLMDRTVDALRTCIVDDVHVASRFADLLATLTENLKPRLVRIAADGRSGKNRRVSQHPSMDGIQDTRPTSAPQQGFLHRSQSQQEAQTSAGAMATQQQWNNYSNHQDVPPSTVMHGISYEPYDLNGQNGSFSVMPPPHFSTSSPSNGNVLTPGYDSAFPHDFNNNQDWFALPLDPIIGMQGADVNQTMYGPDIGGHDMLELLLNGSGNNGNGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5Q1</accession>
    <name>A0A9Q8P5Q1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758599.1">
        <property type="nucleotide sequence ID" value="XM_047902330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5Q1"/>
    <dbReference type="GeneID" id="71983060"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03182"/>
    <dbReference type="OrthoDB" id="5427070at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="127" mass="14067" checksum="18CBA9AFD7F62D6F" modified="2023-09-13" version="1">MGFLEVFKAVFIPALIAAALYAIGAFLVMPLIRQHRNRYSHYLPLDSISQHTNSFRDRLANAVTRLVLPRRMVVIDASGSRRGSVSGEEFVFEDAEGDSMVGFDVGRSDRQVRGANIGNDGRRVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6Q7</accession>
    <name>A0A9Q8P6Q7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759458.1">
        <property type="nucleotide sequence ID" value="XM_047907344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6Q7"/>
    <dbReference type="GeneID" id="71988074"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08196"/>
    <dbReference type="OrthoDB" id="10570242at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="224" mass="25560" checksum="FF09BCC882E663E4" modified="2023-09-13" version="1">MGQTTSSPPTPCRLQQLPNELRNRIFALAVIKDGSILVSKKFSGGKCVVTPAPPPLARTCRQFYHEVMPVYYGNNTFIAYGSVRTHPKMPNKFEEMSRWLRDAEARAVMLDKQQRDGTVRHVKLVISHLPYDFACGDLRRWGTFMIHIEDGNIEVESSGILQAKCICVPRQLASQYRGQLTEFVAKLENHCTEHLLFSKLSYRESEEYCWQCGMLRTVPRAYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6V4</accession>
    <name>A0A9Q8P6V4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_08308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759770.1">
        <property type="nucleotide sequence ID" value="XM_047907456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6V4"/>
    <dbReference type="GeneID" id="71988186"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08308"/>
    <dbReference type="OrthoDB" id="10047078at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051750">
        <property type="entry name" value="Trans-sulfuration_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO15404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="546" mass="61100" checksum="6ADC295461801B27" modified="2023-09-13" version="1">MISSSSRHYIQHHIMAPSVGESIPPGDIHAVSVSFPEWQHMVRWGQRDEELISKMKAGYPRFFIPLIVRKLAARIVERTKHCKDGSQALLFPCAIMAKACQRFFASKGQHDEFIVLAVALDGEVQHLDTGVAQPYSVHDAIYAVTYPDHHAATAKAFWQHTGLGISTRCAHFWMDTLSGVGLKSGSEHSTAQVLPHAEADDAKQEIRARLAEHNSCTELNIGPQDVVLYHTGMAAIYHSGRLVQSRAKQSGHPKVVVFGFLYVDMTKVLQIILGLSVKLYGHASDSDLDELEESLRSGTPIDALYLEFPGNPLLQSPDLRRIWALSREFDFLVILDDTVATSINLNLISCCDMACTSLTKMFSGACNVMGGSITLNPQSRNYPMVREALKASYIDTIFPTDALVMLNNSSDFRYRVLTANRNAEHIHSILRRHPQVAEVFYPKQSTSQRYYDEFKREEGGYGYLLSVRFKAPHVAEVFYNALDVAKGPSLGTNFTLCCAYTWLAHPTELDYVRQYGIVEDLFRVSIGIEGIEWLERIFCYALAACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P787</accession>
    <name>A0A9Q8P787_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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</entry>
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</entry>
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    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P823"/>
    <dbReference type="GeneID" id="71984671"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04793"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF7">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="73"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="364" mass="40189" checksum="586DAA957FF2A688" modified="2023-09-13" version="1">MSSQTIKHHLTLDPTHHQPPTRDETAESSQADLPPPTPKLSHQHPTKSHGKENASLYFIGTATTLLQWQGIRILTDPNFLHAGEHVHLGPGVTGTRVTNPAVDLHALPHIDAVLLSHYHADHFDELVEKSLRRDLPIVTTPHAKEHLADKKSGEEKFTQVHDLNTFENALLDIKTEGVASPDRIPAIKVTAMPGKHVPPGPLNVANDILGAVPPTNGWMLELGSKPAMSTVASDFRSGYRVYISGDTLLVDDLKEIPKRYAGLEIDLMLIHLGGTTIPGPKVPLLMVTMDAVQGVKLMQLIKPDVTIPVHYDDYDVFLSPLEDFKKAVTKAGFDDRVVYLDRAEEYRFHVREGEDVEGMLRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8G4</accession>
    <name>A0A9Q8P8G4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761479.1">
        <property type="nucleotide sequence ID" value="XM_047904028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8G4"/>
    <dbReference type="GeneID" id="71984758"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04880"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="26549" checksum="CCD586B29097731A" modified="2023-09-13" version="1">MILEKLAFEDLIRAQSICKKTREVTRSSLRIMPRHAALSTEYRDDQALINKHIDFDLTLVMCPVDDIGGRFHLIGSNPYDSYDLELFEGPYLFCIGFLRSLEAQPTWDFCSDYGEGWDGKEGDKLHTRTVIIQGRDGETQCLWRYLKVAKLPASGWRLKQEYDGVQITLRSDCYQGHPVKEVKVFPTTVTIGEAWEWLHERVEARHPADPCPDDQRRDAPESTEHRIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8I0</accession>
    <name>A0A9Q8P8I0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)</fullName>
            <ecNumber evidence="3">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_04121</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="3"/>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761272.1">
        <property type="nucleotide sequence ID" value="XM_047903269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8I0"/>
    <dbReference type="GeneID" id="71983999"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04121"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000634">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="242"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO16906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="553" mass="61128" checksum="4C69B64807FB8CC4" modified="2023-09-13" version="1">MISQLPRSLTQLELHNCLLPFNPDDTRDDAAALHSTFVDHAYLKLNAPTTTSSEIMANHPEIKKLAMIGCGSMGGGMALLFAENGCEVSLQDPSNEAMDKVIEQGKKDRVPSKISKYSDYKSLCESLDDTKVFVWSLPHGHVGDSVLDGLMPYLKRGDIIIDAANEHWQNTERRIGKCHPKGIRYVGMGVSGGYQAARRGPSMCPGSDSESLDIVLPLLKKAAAKAPDGSPCVGKIGTGGAGHYCKMIHNGIEHGMMSAICEAWGIMERGLGMSLDEIGAELHRWNKSGELQGTFLVRIGADICLTKDGKGNRVLDSVEDKVVQDFTGEEGTGIWSNTEAVMHHVPAPTLTSAHYLRLASGDRHQRTTVKKTFGSDYPPQKLSVQDKKQFLEDLRMAVYGACLASYVQGMNIIDKADKENHFNVDYYQLLQIWRAGCIIQADYISSKLLMPIYKNYAKKQAKNPLYEPDVAADLKKSFTPLKKIVLQAAEKDHPVPSLSATLEYLKYQTSTNLPTSFYEAELDYFGKHMYDRKDDDVAGLPTTGKYHFEWKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8I8</accession>
    <name>A0A9Q8P8I8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_05195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761302.1">
        <property type="nucleotide sequence ID" value="XM_047904343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8I8"/>
    <dbReference type="GeneID" id="71985073"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05195"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO16936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="111" mass="12427" checksum="C1DBD902D9E45BDD" modified="2023-09-13" version="1">MPEPMLSVQPKLIMLGLGRAPGESLGMNANRSRNNSSPEQRSPPESPHSTDVLAIPKLTILGASYILVPFYIYYSSILNSIYPRLKFFRLPLALLYAWYATKKSALHHPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9A4</accession>
    <name>A0A9Q8P9A4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762319.1">
        <property type="nucleotide sequence ID" value="XM_047905297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9A4"/>
    <dbReference type="GeneID" id="71986027"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06149"/>
    <dbReference type="OMA" id="AMAMDSI"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12432">
        <property type="entry name" value="RRM_ACINU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034257">
        <property type="entry name" value="Acinus_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="56311" checksum="F01D07722FAF4BD5" modified="2023-09-13" version="1">MTTDYSKLKVTELKDLIKDRGIAQTGLKVKQQFIEALEAQDAENGDGSGGDAAGEADKIDEAADTGATESATAEDVEGKDAPPDGEANGGDDSLNDDSETTNKRKRSATSEIQEESASKKLKAAEEDSVEVKGVEDVVAEAPAPVDTEISAADKVLPHGSSDDVQRDASMDDSEQTSNAAPTEPRKDSDQGAAADATLSGQHASVSHDDYAAGPPSRHPRSRALYIRELLRPLQPNALREHLETIAQSADSTSGSIDDFHLDKMRTHAFVLFDSAGAASRVRAALHNKKWPDEAMRKPLWVDYIPDDKVREWIDIEVTRGDNTRWEVAYESTGMDTDTGVIATLQEVDARPSAGRQPSINSAAPRGPSGAGEGMPNAPSGPRQRSGQTQAQAPPHSAPPPTQRAPENRTFDSLDQRYSFTEMKPKLYYQPVPGDLAQRRLDDLAASTSRDWNDRDADPSAYAEGELFRYTFEDGDRLVDGGADFGLFGRRGRGGGFGPRGDRGGRGRGRGGGDSYRGGGRRPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9W0</accession>
    <name>A0A9Q8P9W0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762892.1">
        <property type="nucleotide sequence ID" value="XM_047906210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9W0"/>
    <dbReference type="GeneID" id="71986940"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07062"/>
    <dbReference type="OMA" id="DYDCLDA"/>
    <dbReference type="OrthoDB" id="78947at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO18526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="129" mass="14356" checksum="527E0DDA966F4AFE" modified="2023-09-13" version="1">MPILPAFEIPDTAAALPVDDSSFFIAFLSSKDPATQQPWCPDVRATLPTLEATFQRDESPTAAFVEVGQRAEWRDPSNVFRTKWNVHNVPTLVRFQRVGDSVKEVGRLTEGEIMDAERLQRLVSGEGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAA8</accession>
    <name>A0A9Q8PAA8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763175.1">
        <property type="nucleotide sequence ID" value="XM_047906522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAA8"/>
    <dbReference type="GeneID" id="71987252"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07374"/>
    <dbReference type="OMA" id="IRCHEVR"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="583" mass="65869" checksum="6E7716A5F07527EB" modified="2023-09-13" version="1">MRLLSTSKLEFRTFPDRDGKTPAYAILSHTWSTIADEEVLYHDIINGTVTTRKAYPKLEGAMQQARPSYDWIWVDTCCIDKTSSAELSEAINTMYNWYEKADTCLAFLEDKAFHSVSEIVQSKWFTRGWTLQELIAPKDVLFFDKYWTSIGSKKSSTIYNAISERTKVGVDILLGTTPIQSVSVAQRMSWAAGRKTTRDEDMAYCLMGIFGVNMPMLYGEGGKNAFHRLQEQIMKDSNDHTIFTWTSHPDAKTGPYHGLLADDPHVFANAGNFVGYNDWEDAEPFQPSNRGLRINFHLEPTPREAGLGENTFYAALNVPVPSQIQGYHGLVAIILQKLDVGVKQFTRIRCHEVRGMTTRAGYASTVYVRQKADAQDHEALTPYHFMMPRRLMTPQDEYVLDRVACYPLAEPHIAPRPLLQAWLAASQASSFQVIKRAGKLAAILYFRRKSDNAWLSILLGSRTDLEVGFTTLAGFRQVSNLTEAEQDLQLYPSGTTIEAGNHFVRIDVEVKVDMPRKLYFLDLTIHGRPRTPPPPLLPEVVYNAVDFLADTMLDTVIGAADETQQRAKSVSRRGISLRRSEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAB9</accession>
    <name>A0A9Q8PAB9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763165.1">
        <property type="nucleotide sequence ID" value="XM_047906188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAB9"/>
    <dbReference type="GeneID" id="71986918"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07040"/>
    <dbReference type="OrthoDB" id="4159781at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="370" mass="42123" checksum="88048AB10103D465" modified="2023-09-13" version="1">MPERLFVSFEHCHTKKDPSSTRAVRSWVTKVQHARQPRRQVDRASPTTKEEEQEHANQPLRNLPTHDFGDLIVTSAESAKVVTWSWEPVDPTSGPSPTTRRRIQAHVAHRQHEKRRQSERGKSMPLKSTSSTSSTFTSPLPTPLLERTFSASPPFYIQDPADPLGVYARRLNTSVPVIWSHYLWREREHGRAFGEHYPQFQGWGPKYLHPFITNNRAFLATTVLFTGAHLRFLQGHDTMSIPILQLRSLAHDYVQAAIDSESERLADSNMLAIVKLALLEAIFGIKEAYKVHMRAVARMVQLRMGLLNLGMEGYTARLLVWFDANLSATAGSPRYLAEEASRTTASTDLRRNEETFRLGVHERMGHNDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAX9</accession>
    <name>A0A9Q8PAX9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Translocation protein sec72</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763509.1">
        <property type="nucleotide sequence ID" value="XM_047906618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAX9"/>
    <dbReference type="GeneID" id="71987348"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07470"/>
    <dbReference type="OMA" id="KMYTLAI"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF3">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="204" mass="22838" checksum="C190EB1BA45EA2FE" modified="2023-09-13" version="1">MDSTEVFRELPLTIDPETKAISTSDSTLLNEIEELNKMNRAFVALDVPNQIPPPPAPVNPKRSVQITKLKESGNGSYKKGQYAEAVKMYDLAIRMAVDRPGWEASGLVREELSTLYGNRSQALMAQQRWAEAATDAEIATEMKKVGNVKCWWRRGQCLREMGRLEEASEWVKVGLEFERAGPEKQAVGELETLARDLETALNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PB19</accession>
    <name>A0A9Q8PB19_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase gsfE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763556.1">
        <property type="nucleotide sequence ID" value="XM_047906605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PB19"/>
    <dbReference type="GeneID" id="71987335"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07457"/>
    <dbReference type="OMA" id="FGTWIDK"/>
    <dbReference type="OrthoDB" id="1731983at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF0">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="5"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="377" mass="42329" checksum="18E2AF286BC4F194" modified="2023-09-13" version="1">MAKVALITGGNGITGSAIIEYLATQTTAEEWSQIVVTSRSRFQTTVSDPRIKFVALDFTKEPKSLADLMKDSCAAVTHAYFSSYVHKDDFAELNTANQALFENFLAALLQVAPKLENCTLQTGGKYYNVHLQAVASPAREEDPRIGRTEDNFYYSQEDFLAAKQAGQNWSWNVIRPEAIIGHTGKPNGMNSALTYALYFLVCRELGREAPMPTNQIYRNGADDCSDSGLIAHFSVWASTNPKCANEAFNVVNGDYFQWRYMWPRIASYLGATASSNPKFQKPIPQEGSVQQEFSLAEWAADKRPVWDGLCDRLGRPEAKATWDAGTWQYQDWVFHRAWSATIAFNKAREYGFTGYRNSYKSIVGAFDRFREAKQIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PCS4</accession>
    <name>A0A9Q8PCS4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764440.1">
        <property type="nucleotide sequence ID" value="XM_047909271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PCS4"/>
    <dbReference type="GeneID" id="71990001"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10123"/>
    <dbReference type="OrthoDB" id="3641865at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="458" mass="50445" checksum="DBBD7CDB223E7C8A" modified="2023-09-13" version="1">MADLQDQEEQIRRRQRGIAFFDHGDSSPLEKASTPRGVRYRTASAEIAVQVVRYMILALRGLLILLATAIILGIGLRGIGKSCSHLPSRTPGCRSALIKSTTPYLSTFKNGTTPLTGTFTELTNIVHMGPSLSVLGTAMHLASANFSSTHDELKAFPELYQTNSTNLDNLTDIMGAAIGAAELFSRSDFSYRDQSLLWGRNAVESIGKMVDTYIHALNETSTLTWSAVEQTLHRIPFGARRTPSYDIAHTYFYFGGHQWLEIEQLVYMANDSSIALSGLITELDKLSQHVERVSAENKKLCTGYDRTSNSTSTSTNSTLASLCHLDPSLQLPKLRSIRSASNWSRSVVEKALAHYFRALSSIKIPTNALQLDVKGYESLIPAKGTVSTKKLKRLLMTEESQLMEFAKAAHKGEALMSRLGRTLTNGNSVKKLHEAVDAAVVKGEGGGHRWWGEEHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD22</accession>
    <name>A0A9Q8PD22_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_10666</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the VPS35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764572.1">
        <property type="nucleotide sequence ID" value="XM_047909814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD22"/>
    <dbReference type="GeneID" id="71990544"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10666"/>
    <dbReference type="OMA" id="YIRSREY"/>
    <dbReference type="OrthoDB" id="10258141at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030906">
        <property type="term" value="C:retromer, cargo-selective complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.660:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
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        <property type="entry name" value="Vps35"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
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    </dbReference>
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        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO20206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="877" mass="98831" checksum="1C0A68804B50B5EA" modified="2023-09-13" version="1">MGSPPPVEDQARLLEDALSVVRQQTTLMRRCLETPGKLMDALKCSSTLVSELRTSSLGPKQYYELYMSVFDALRHLSVYLRESHPVNHLADLYELVQYAGNIVPRLYLMITVGTVYMSIEDAPVKEIMKDMMEMSRGVQHPVRGLFLRYYLSGQARDALPTGEGDGPEGNLQDSISFILTNFVEMNKLWVRLQHQGHSREREQRTKERQELQLLVGSNLVRLSQLVDLESYKNGILQPLLEQVVQCRDVLAQEYLLEVITQVFPDEFHLHTLDQLLAATARLNPHVNVKQIVIGLMDRLSAYAARESETKTPEQRQKIEDKSVTSLLEKLKLSKEAGDAEPVKPTENGEEVHDETAPNTEEPASSEAAEETSAKDEEEPKTNGQKHNGIPANIKLFEIFYEQVVHIVGMQRLPIQDITPLLVSLVNLALNIYPERLDYVDQVLHHATKEVARFQNSADLHSQQAQQSLLALLHAPVKAYFSLFTALALPSFVPLFQQQPYPTRRAVAGETARNILRNETKITSQAHLDGVLSILSVLIKEGMQPSSGYTGAAARRNAIETEETVEEQGWLARIVHLIKGADNVSQFKLLQTARSAFQEGNERTKYTTPAIITQSLKLARSFKRREHLSSDDYSAQSSALYKFIHTTISALYTRVSSSGVPDLVLRLFVACGQVASQCESEDVAYEYFAQAFTVYEESISDSKLQFQAICIISGALSGCSERFSRDNYDTLITKAALHGSKLLKKPDQCRAVYLASHLWWSVEKAEQPEGVESKEPYRDGKRVLECLQRALRVADACMDTAVSVELFVEILNRYVYYFDQENDAVTTKYLNGLVELIHSNLNTTENASGLEHPRKHFQKTLDYIRSREYEGVVTTAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDG0</accession>
    <name>A0A9Q8PDG0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764814.1">
        <property type="nucleotide sequence ID" value="XM_047909100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDG0"/>
    <dbReference type="GeneID" id="71989830"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09952"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO20448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="264" mass="30658" checksum="7EE2DB0C5F1E7C59" modified="2023-09-13" version="1">MTSPQDSQAMALATNARTTDGIRNTVSDGQVTTRTTRSMSKHSKENPGSSAQEEQRERIQEDPRPNFLHTFLYTFPGEIRNLIYENLAPRPWGYVDITRFDIERFQHDHGGGAFAQFHPTIASEYRGYWCPNVTFMWIIGLHSQPKRGAEPHNVPHDIDDVDFEPWHKWIKQFDDVQAGDIESVRFRLEFFEVKVTISVPKRVGEKFRVEFTVQQRCGHERLREEQPFDGLQQELDGVADSGEQRKEMLNRVAMAVVGRVRMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC2</accession>
    <name>A0A9Q8PEC2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765380.1">
        <property type="nucleotide sequence ID" value="XM_047910497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC2"/>
    <dbReference type="GeneID" id="71991227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11349"/>
    <dbReference type="OMA" id="NANFDEH"/>
    <dbReference type="OrthoDB" id="5313204at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="92" mass="10628" checksum="E6D3B926736A9A56" modified="2023-09-13" version="1">MNNIREKLKRKLSLHDKNPNIDEYDNADDVDEETTGHLHREIEKAEESNQPYGKPGSFLNKLILHGNKKTEDEMLRGQQANTQQLAKENVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEE3</accession>
    <name>A0A9Q8PEE3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765304.1">
        <property type="nucleotide sequence ID" value="XM_047910188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEE3"/>
    <dbReference type="GeneID" id="71990918"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11040"/>
    <dbReference type="OMA" id="HACCAPI"/>
    <dbReference type="OrthoDB" id="5525680at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF3">
        <property type="entry name" value="DUF DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11150)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="74"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="21105" checksum="875A1DF182CA8B20" modified="2023-09-13" version="1">MADPRSSLESYRSSIATISSDDQRLMHEPYNPLHNVFGSKPVLVHQRNSLHTNAFSQWPLTGPLLFDNNNSDARDHCAAERTFLSWLRLAIYMAIVSIAILISFHLKHQPTALERRVALPFGIIFWLLALACLLSGLSNYIKTVNRYSRRQALVQSGWGTQVVFTVVATAIVAACVLLLSTQGESRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEJ3</accession>
    <name>A0A9Q8PEJ3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
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        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
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        <location>
            <begin position="482"/>
            <end position="691"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
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        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
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            <begin position="44"/>
            <end position="53"/>
        </location>
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            <begin position="155"/>
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        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21013.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="693" mass="77512" checksum="DD0A73C73B5F64EE" modified="2023-09-13" version="1">MSVPNGGAPTPRRQTRTASSRQQTPLPALQTKQSHAYGAPGKTHLNSQMTTDTAEIDAAFTTTGFRRTRAATAKEPTPAPAATPAAETTTRTRKSKKRVEPEVLPEEDLEDETNDGDPNGIDSGARGDGMRPDTRLDTSLSYDKVPEPQKRATAPKEPSPSLVPSVEPARQSPVEQVEALPEDVEPWRITVLFWTFWKYAVPSAQIFFVLLLGFVIMSGLLGGLGLFASLLPLPAMYALKRDVFFYRVGTLLYGHGTPAEALWYNVKNAELTMSEIQMINITNVTLPQNQYLINQNVYARLTNDEWAARLLKETVDTHGETLRELKRILPPLTAMITEDGQWKFTNDFLQAYGEKMLSSDAAPLWDKFMEINEERLIQAHRGILQTEVNGVIENMQIVTHDQMQQAIVENNDYMMANFNETVASFRTHLVKEFRGIAIEVADDAIKQSPLARLQNGAVAYATIIQNAQKRMREVNYLSIGLGAMVVPLYTSPTYKNPVLAQGWVDWVLYRTGLKTWPLLPFVPALPPTSALRDWKEGAECWCAAPSGDEMALGQIAIQYPHKIYPGEFALEHIPASGTRDIAAAPKKYEVWAQVDNSTEALRVKALLDQDFDLHFDWECGPPPKHNPSRWVCIVADEYDIHSSNYIRSYDLRVGAERIGLTTQMIAVRVVENWGSPDHTCIYRVRMTGKEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEQ9</accession>
    <name>A0A9Q8PEQ9_PASFU</name>
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        <submittedName>
            <fullName evidence="8">Beta-catenin-like protein 1</fullName>
        </submittedName>
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        <name evidence="8" type="ORF">CLAFUR5_10841</name>
    </gene>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetidae</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047909989.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71990719"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10841"/>
    <dbReference type="OrthoDB" id="1898821at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
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        <property type="term" value="C:spliceosomal complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CTNNBL1_N"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </feature>
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            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO21080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="579" mass="64448" checksum="48017447C0C1F1E4" modified="2023-09-13" version="1">MTSVDELFRKPNLPTGSHKRKLEVPDADAAYKATKLTSTSSPNGNGNHASVEDEEDDDQEAGPELPPDDDGDDEEGRFFGTGMSNDTSEALNYIDEQDGEEVYQEEKIDSAWLRRLCTSFEKKVKKNAELRARYEAEPAKFIDSEADLDAEIKSWSLLSEHPELYGEFAEAESAVTSLVGLLAHENTDIAIGAIEIVAELLDEDVQAEQEQWDALVIALLEADLLDLLMRNLARLDEENETDRSGVYHSLAVLENLGGQQAVAERIGQEKVLNWLCERIGKPEKPLGQNKQYAAEVLQVLLQSSSILRKRLAVDIDGVDLFLQVLAAYRKRDPAKDSHEEEYVENVFDALTCVVDEAEGKAKFVAAEGVELMLIMLKEGTKNISQRALRVLDHAVGGQGTEATAVCETIIQAAGLKTLFSRFMKKSDHSTVEHLLGIFSALLRLLPGESAPRIRTLAKFSEKDYEKITKLLKLRTDYAAKVAAVDSVIKEERKGLDAEEVEDREAEWFSRRLEGGLFCLQMVSVALAWLIAEDTEIRRRVSAELGDLTTIRESLEAQKAGLEVEDEDTKEMLETLISFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEU1</accession>
    <name>A0A9Q8PEU1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEU1"/>
    <dbReference type="GeneID" id="71990991"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11113"/>
    <dbReference type="OMA" id="RYYTHTI"/>
    <dbReference type="OrthoDB" id="3634448at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="229" mass="25942" checksum="A7B8A753DCB61A58" modified="2023-09-13" version="1">MAATPMDELRGRIQGLPQELYDMIRDFTLTLDTSENGNITINRDYKPPVQLQIDSATRNKIAQEYYANTTFTFFKLHDGEALCIKWLDSLSPEARTSLREVRLEAPQPKRLSVYDGQPEGQLYLLLLSLTQHNMYMSGQSKTVARALLQKILHTNIQRERRNGQLEVMWLTSGNRHLRRIMVEDADRPAGIAVLEGEKLGGSSGLLVAVKTLGNRLILGAQTVCDTRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG02</accession>
    <name>A0A9Q8PG02_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766161.1">
        <property type="nucleotide sequence ID" value="XM_047908623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG02"/>
    <dbReference type="GeneID" id="71989353"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09475"/>
    <dbReference type="OMA" id="WGMQNIA"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000224">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF34">
        <property type="entry name" value="PROTEIN HOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="50"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="538" mass="59492" checksum="573928F156229A60" modified="2023-09-13" version="1">MEEANGELLPGTLQLFVQTEDGDLRDQEITLTPPPTNSPNDPLNWSPWRKCWHAALVLYITALTAATSNDAGAAGDGMLDELGIPYSVANTAAGVLFLAIGYWALLASPMPWLYGRRLQYLVCLVFSIVGSIWFALIKNRQDSVWNQLFVGASESCAEALAQLSLSDLFFQHQRGLVLGLYILATSIGTFLGPLVAGYIAIDSWRWVGWTGAIISGGTLVVFYFGLEETAFHREAILGRHVGGQPAQTMDDEKKIAGNTAQLDARVSTESVADLTDQKKTYWQRIAVITPAPNMYGTGLKQYFQRLFYTLRIFLFPAVLYSGLQWGAQDAWLTFYLTVEEDNYYNAPWNYSNQAVAIMNVPTLIGATIGCIYGGWFSDVFVRWMAKRPGRNGISEAEDRLWLLFASAIINPAGLMLFGIGSGNGWSWPGPYIGLAMTGFGFSCAGDLSMAYLMDAYPDMVLEGMVGVAVINNTLACIFTFTGSYWIDASGLSGTFIGIGVLSFAFQMTTVPMMIWGKSCRRWTYQKYQRFLYLRDGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGM1</accession>
    <name>A0A9Q8PGM1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766421.1">
        <property type="nucleotide sequence ID" value="XM_047908574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGM1"/>
    <dbReference type="GeneID" id="71989304"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09426"/>
    <dbReference type="OrthoDB" id="3650750at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18634" checksum="EF99B1704A46E371" modified="2023-09-13" version="1">MSTTPPSTPTLNDRIQQLPQELQDMILDFTISRDHLDPILLNPPYHPPLALHLNRMHRAKFAAQYYSTTTFRIELQQRGAIMVSTMINFLSSLPVEHLKMLRRVEYPGAALAERWTDAHYIAVLRLSNCKLHLPERVRAHLAAHALAMGYVDVDDGGKVKWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH04</accession>
    <name>A0A9Q8PH04_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Acylphosphatase</fullName>
            <ecNumber evidence="1 2">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_09010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1 2"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766618.1">
        <property type="nucleotide sequence ID" value="XM_047908158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH04"/>
    <dbReference type="GeneID" id="71988888"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09010"/>
    <dbReference type="OrthoDB" id="7961613at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268:SF4">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO22252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="99" mass="10980" checksum="C1085E97F532083C" modified="2023-09-13" version="1">MRAFSTITYRMSKRISFKVEGVVQGVNFRSWTEQKANGLNVTGWVKNADDGTVIGEAQGDQSSLDKFVQHLNMGPQPAKVKKVDRKDIDSKDGESSFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH13</accession>
    <name>A0A9Q8PH13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dothistromin biosynthesis peroxidase dotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09349</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766633.1">
        <property type="nucleotide sequence ID" value="XM_047908497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH13"/>
    <dbReference type="GeneID" id="71989227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09349"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="183"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO22267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="550" mass="59491" checksum="51A3EBB91121E494" modified="2023-09-13" version="1">MSNGMLHATTSPNPVRLLELSNNRKEPCNQATCPGGSFSSEQHATPMLLSTNRRGHGRRPTCSALAEDKRLHADLSGLPLLLLSLFAWTSSSISSSFSKSTLKLRFRPFVFAIAHAARLNMTSFVLLGFALQAVAFPFALEDVQKRQVPSTELAQQLSKARTNCGNIPCLVFNEQEQYVSNQGDHAFASPGPDEIRGPCPGLNAAANHGYLSRTGVTNLLETITGLEAAFGMGPGLSGFLAAYAILMNGDPLLLTWSIGGAPPSNTLTSGLLGQAQGISNTHNTYESDMSIGRCDAYLNNGDAHSLDLDRFKQAFETGMSDDRYTLHGFASDFLQKGRQSISENPYFFSGPFAGVVVAPAAYFFVINLMSNHSAEEPSGYLNGDMFKEFFAVEGEYPSFKWNPGQERIPENWYRRTITNNYDIANADSDLAVQYAAYPESLRLGGNTNGVNTYTGVSLSDLSGGVLNAENLFDVDNPRGACFYAQLAQSLIPDAASTLLSVLSPVTKLVNDNILSVIGGMDCPIVDKFDQSLFNQFPGYKYSPTGPATNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHD5</accession>
    <name>A0A9Q8PHD5_PASFU</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">CLAFUR5_11749</name>
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellales</taxon>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766864.1">
        <property type="nucleotide sequence ID" value="XM_047910897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHD5"/>
    <dbReference type="GeneID" id="71991627"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11749"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="85" mass="9762" checksum="2B830C5D29B8B03C" modified="2023-09-13" version="1">MGTWKGRHKPPTPAQTRREFERVLKIVYAVKYKLTANSIRLFDKEVENAGTVVEMPQEERINPITDVPNKVEITVAVHSDWTTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI14</accession>
    <name>A0A9Q8PI14_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71992358"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12480"/>
    <dbReference type="OrthoDB" id="3660917at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040281929" evidence="2">
        <location>
            <begin position="18"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO22802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="241" mass="26394" checksum="6F2E0E61A6E32FDB" modified="2023-09-13" version="1">MRLLATLVGLCAAVAIATPQISLSRMDPDEPLSQPTDAPTRPLNQHDTSNEDPAVLFHQLKATTPDSGIMELGEDGVARSYDQDGKVLDALRLTNSQLTSLLSEATSSDPAVLTWYRSLFTGISGYDVPSSHLFNPHPSLLPARFQPKNNNNNNNKAPPTTTSSSNNHALSMHTPSPTFCYDYVCANNFDCDLRNCGKCVDIEMFGQPVGGGRCNRNAFVDQPYMPGESSETCWWDWFFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI69</accession>
    <name>A0A9Q8PI69_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase family 25 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_12258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
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    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047911406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI69"/>
    <dbReference type="GeneID" id="71992136"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12258"/>
    <dbReference type="OMA" id="YAITLPM"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="44249" checksum="1FC3A872038CB83E" modified="2023-09-13" version="1">MLNRAFTAPAGGRVGILLLVAILLITILAFTYPSLKPSLPAFRGRTGINNDAVGKGDLLDDVLNATLGFEKIFVVNLPLRTDHRDAISLAAHFTELQVDYADGVTDVDSRAFPPWGNESDLALGGLKSWRAHMNVVRRMVEEDISSALISEDDADWDLRIKSQMHTFARASRLLVQPLRGTQDQFLDPSYPSPAIGEDAAEFNISSDYGVELPTSSPYGDLRHWDALWLGHCGSDFPAASDLKAPLGRVVIPNDDTVSTNVNKEFGGEGIFAYPPRTRVVSRAWQSTCTFGYAITLPMARRILYEQGVWKVTGPFDMMLRSMCHGSEGRRTRTCLGVQPALFAQHKPIGNEATFSNIDEHHEGYNAVPQTPNIVLSTRVNFPKLIEGETDYHESFGSGKTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIE0</accession>
    <name>A0A9Q8PIE0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767362.1">
        <property type="nucleotide sequence ID" value="XM_047911360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIE0"/>
    <dbReference type="GeneID" id="71992090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12212"/>
    <dbReference type="OMA" id="GMHAFAV"/>
    <dbReference type="OrthoDB" id="4095724at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040239476" evidence="1">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO22996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="215" mass="20362" checksum="35091B9DFE8A38E2" modified="2023-09-13" version="1">MRYSQALLLPIALAAAQDLGDIGNAITSVGGDIASAAESIGSQITDGAGDIGSVITSFGGSVFTVATNGAGDVLSTITQEAGAFGSKVTSVGGSVFTVATNGAGSVLSTITNEAGEFGSKVTSVGGSVFTVATNEVGSVISTITSAGGEFGTRVTSVGNSLVTEATDAAGSVVSTVTEGAANAATGTSEAGAVITKAPYVAGGLLGAGMAVVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIK3</accession>
    <name>A0A9Q8PIK3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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        </citation>
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        </source>
    </evidence>
    <sequence length="613" mass="65820" checksum="A443C8BC932636F3" modified="2023-09-13" version="1">MAHSRFGSQHDSKAFPFRQLLVLGICRICEPIAFMSIFPYIYYMIESFHITNDGNRIALYAGLVTSVFAGAECLGAGFWGNLSDRIGRKPILLTGLAGTGVSMLMFGFAPNLPVALLARAVGGALNGNIGVLQTTVNEVVKVEAHQARAYAIMPTVWCIGAFVGSGLGGSLADPVRNYPDVFQPGTIFDKFPYLFTNLVCTGVVVFSMLVGILFLEETHEDLKFRRDIGLEVGDWILNRFRKEPVERLSSRKGDFSDETLLLIDDLPPDYQSTASSPELSPTSLAGLPPPAYRSIDGSPRGSIKSADEDLACDVEEALSRTQESHKSKAGAHSAFTKQVILNIAGYGILAYHTISAEQLLPVLLSMPKSDSPPHLPFGFTGGFALSTKTIGGILSIQGVIQMIATIIVFPIVNRRIGSLWTYRSVVMLYPFLYLVVPYISLAPDALKLPLIYTALVWKVTAQAFAFPSSSIMLANSAPSSKVLGSLNGAAASAASACRAFGPTVSGILQSAGLSLGTLVLPWWVNTCIAVLGAIISMLMVEEKRRTFESEKEIPEPPPSASDVAGAAEYSSGMVAAAESSNASCDNLLTAPDSPLLSRISMDIRRHNRLDSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLI8</accession>
    <name>A0A9Q8PLI8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768958.1">
        <property type="nucleotide sequence ID" value="XM_047913119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PLI8"/>
    <dbReference type="GeneID" id="71993849"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13971"/>
    <dbReference type="OrthoDB" id="3640838at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="226" mass="25181" checksum="8E1F7BBF48898806" modified="2023-09-13" version="1">MCRQPLPSSHPQQKSFLSSACFLTIEHISPAVQQQTAKRNATMANDSRNSRLLGLPAELRNNIYRLALVEGEIITPAQGSMPSVPPLLSTNRQIQAEAASIYVQENMFAFDIDNLDGSKVTELCSAALVRRHRRVRTGVDLEEPHSSSWSNLKIWLRAFYAKRSLRLALTDRGPDFKRCAAAGQLFDVVGRFMDMSPKPSWNHVVESQLESMRLALAAVDTSGVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMA8</accession>
    <name>A0A9Q8PMA8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc cluster transcription factor acuM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_14339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769414.1">
        <property type="nucleotide sequence ID" value="XM_047913487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMA8"/>
    <dbReference type="GeneID" id="71994217"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14339"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053045">
        <property type="entry name" value="Zinc_cluster_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986:SF7">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO25048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="550" mass="61261" checksum="74C3D5691ECA2B80" modified="2023-09-13" version="1">MASPVNEQQQQQQQQIRAGTQESKPSLTCAKERQASPKRKSSEAATATENGEGKKKRRKVNHACVYCRRSHMTCDLERPCARCKKRDIGHLCHDEPREPPKRTKSEMSTADIAPAPMDTPDGQQSIPASNGVAQYGQGNGDMNIGLVNGSANPHLAQPKPVSPVQLQRPTPQSANSNGTNNFLQNFDWSSNAAGNQFQDMHHLHPNYMFNTSEVTNEYNLLNDFLSSSLLDDNTGLYSNDDAQALFNDPLLSTSSMNALTANSLPPPTSSSSSNRPNPIQQLQAQSAAGIELSRPSSTFPPTGIDSKARDKFYMTAADPAGLDSASNRLHALLKSKWDAGMLKPFNYVKGYSRLSQYISKHLTRESQLRILKQLDRFRPKFREAMQGLTDVQLVLVEMWFERSLMEYDRVFASMAVPACCWRRTGEVFRGNTEMADLLRVPLEKLRDGRLAIHEIVAEDSLVSYWEKFGAIAFDQSQKAILTSCALKRPVERAKSPVKGDAGEKERGEKKQVPMETVRCCFSFTIRRDGHNIPSLIVGNFLPITPRRQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PMM9</accession>
    <name>A0A9Q8PMM9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769540.1">
        <property type="nucleotide sequence ID" value="XM_047913603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PMM9"/>
    <dbReference type="GeneID" id="71994333"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14455"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="269" mass="30609" checksum="DD89C4986D51370F" modified="2023-09-13" version="1">MAMLTTLFHRLRMKSHVRTMRITAGQIDCNMRPSYIFLKPTAPYLRLQSFKKERGACIEPSRYHEEPLEWFEGIVSAVYACDLPITTLTMDTVSADLGMPFEKWHHEDPKIMEYVGDLFTPLESLDLPLVCINRDPDSRHAEFSAVAKALTSATKLRRLRIRANTEEEGSMHDILDLLTCLPDEALPALETLILEGGEIGTLRLTQMVKARASLRRLELEDAYLFDDLDLGGQVFGDDYEDAAEEVMRVTGFREVDIGADVELGDVRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UQS0</accession>
    <name>A0A9Q8UQS0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763410.1">
        <property type="nucleotide sequence ID" value="XM_047906552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UQS0"/>
    <dbReference type="GeneID" id="71987282"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07404"/>
    <dbReference type="OrthoDB" id="9970124at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="80"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="30209" checksum="05174188E2FD7D8B" modified="2023-09-13" version="1">MSLKTLRPAYTSLATRTLSRATARTQLIDRHFTPAFTTIRNFSATKMAPEPERDSEGVEEWKKRAPYRIHDSNEHFKHRYEASCHCGKVEYELSREEPLDSKLCHCTTCQTQHAAPFQWAAIFKKDDINFKNGHHNLEWYDPSTKSVEHQLPCKVRCSFCHSPIMDEGRNMILLFPSLIHFKSDKDKENFKPRMHMFYSQRVMDIPDGLPKWTGLNEGEDSHLIEDSPPDMVRDLERRRVDEQKNRSSFEKGTHKEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UR26</accession>
    <name>A0A9Q8UR26_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_07623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763740.1">
        <property type="nucleotide sequence ID" value="XM_047906771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UR26"/>
    <dbReference type="GeneID" id="71987501"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07623"/>
    <dbReference type="OMA" id="SDWFQGK"/>
    <dbReference type="OrthoDB" id="5377009at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="500" mass="55093" checksum="28E23534623418E5" modified="2023-09-13" version="1">MGDLRGATRHQQQANSFYAPSQRSIINPDLTSTAYHGAAGNIDSHWNAPPAIRLDKDGFQDIQLCEESRLIRECAATTSPPTREGLGNRLLSTIQQQSASPTATALARSGTALHNRARSWAAYVPKLNTNSNQSSPTKGQPRPANEKLPNKLFGDLFHGESAPVHLGVPTSPTKELDESELVMDYQPGFTERPSARHARRGSTMSVKSTKGPAKTSWFGRKASTPAPKVNAIEDEILSININTSLFPHGQGDTLSPQSYNDLLLNATNLLQRMQASYKEKVEYIASIQPEIDAQKEEVEEAEIRSAHLKRQLEDLGKQQEEQKQVNEELMTMLSETKMKLSEEREKSKTIRLVPRDTEGGASDDESRRRGKRRSAGNASDSGFESDADTASVFSSGMQTPASHRQPHFMLSDHDATPRRRALSPRESVASSNAWSGSTKHSTVGNTVAWTTLEQLRHENRQLRMEKEVIQQNLQGCIEIVDGLAGGLAGNFSKLEPYSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URC8</accession>
    <name>A0A9Q8URC8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase MEC1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">ATR homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">DNA-damage checkpoint kinase MEC1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Mitosis entry checkpoint protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">CLAFUR5_10583</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="26" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763966.1">
        <property type="nucleotide sequence ID" value="XM_047909731.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990461"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10583"/>
    <dbReference type="OMA" id="SMYIGWC"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000031">
        <property type="entry name" value="Phosphatidyl inositol 3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058681">
        <property type="entry name" value="HEAT_MEC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF125">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MEC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25385">
        <property type="entry name" value="HEAT_MEC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="24">
        <location>
            <begin position="1255"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="23">
        <location>
            <begin position="1944"/>
            <end position="2267"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="25">
        <location>
            <begin position="2247"/>
            <end position="2279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00030459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="UJO19600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2279" mass="254445" checksum="343991281F50EC08" modified="2023-09-13" version="1">MARRTVTVNGTHTNGDAPPPSTLAAQIVQNHGETATFGDMLQEMLSDQAAAQESDPHVNAQLVSVLLQAGLLPLTTDNPFANTEDLLQQAKDSITVIERTLKRQPEVAITQLSSDGPQLFLSLLATLASLCGRPKCQDLRVHPLLSSICTGLDKSLHTWKQAHVLREIVQESVDDALFALEALTATNIQVTLTLPPARSVGKLWSHGENSITAPPGTTATIHDAHRALMVAIELSLVDGLVRPWYQETNLRLQQVAFKLRSHLEKVELWQHVLQHLQRLGDSDNNEIIAPLLRETTKTQDVVMGDDDNLSTAFQQQCMLHPGTIRRRKPPKRRKISIEGLIVHATNAAQRTAWLAGGPETAQALYVTMSDQDKCTAWQSLADHAQHDLAVAVATVSKLITLPELHDTKRPRVLSMSAVAACAQHLNNKQGITLGSSELGKYCLQNLHSSSRELRIAASRALPAFLRHDLDAEVRDTNRHFALECLRTLSDRDVASEQETLIVAWGQVAIACGDRELNLVLLRLVDYLGHSNNLICGLAAAEIENIAAAKCTTVMEMFQPFWRSIAVSAVQDLPTRPNKTQQLCDLLNTDVDSFLSMTQRDTLPALVLAKKQDIVQRIAHAAGRDSIRNVCLQPITNLASILAVLLMQSSGDVEDSVFGCLTAVDSAFKDVDLASLIRLEPVQIACELLKLCADETDTRKSRAYQAFQNFANIEQAAQGQRRAHAKASRAVIALFDKHILGILTNFSTILETGPDFVADKIRCLKGIEEIFTLTKGNISVALPQIRACLHVGLDQPALHEVAFGVWLSLVDCLLQSEDVAEIVDETFVLIVRYWPTISDDMRQKVHDSVSSLVKAHNITLTENIMTLPSLHSCTPLLNKFAAEFQRLKDQESVESHCKAFTRRLRAESDKVVQQALVELVPYLDINQAFVHEQAASEHPSVVLPELLRALLDVTVKYSTVNEQAAELCGKALGIIGCVDPNRVEATRKKRQVLVLSNFDTASEVIDWILALFEDVLVKAFKSVTNAKAQGILAYTMQELLSFCNFGELSQLRPRASQAPEAYQRWYNLPEHVRTTLTPFLSSRYFVVPNKDLGPPNRAYPGFSLDNSHDKWLRSLVFDLMHKAKGDNAKAAFPYVARLIRYHDLAIARFVLPYAILNVVIGGTVPEVQGLTNEFLAVLSCRSTLPQHQECIRLCSESVFGALDYLAVWLRGKKQQLAATRTEAYKTGLSPTEFDEARDMGQIETVESFLASIPADVIAEQAVDCRSYSRALFHWEQHIRKKRSLIPSPRMTEQHEMLYDKLQDIYSQIDEPDGLEGLAVRLPIISDEQQAFNHAKSGRWTAAQAWYELQLAEQPTSTALQQSVLHCLQETGQYASLLSYAKSFPKEGDSAQAHLASVAQASWMVEDIESLSTSVKLQNENNHHDFNIGIADILLRVGGRSPELFEARVSQLRKSVTESLSMASTDSLQLCHSELLKLHVLHEVEVMADCDPSKGLDLLKCLDKRLTEVGSYVQDKQYILGVRRAIMRLRPSQFPLPHVGTLWLTTARLARQAKNTSNSYKATLKAFDCGLREARLEEARLLWHEGHQRQAVQLLENAIESGMVTDDNVEADIMMTDVSNSTKGSASEINGYKQDRLNARAVLLLAKWLDASGQSQTQDMSDRYQLAARRCQRWEKGHYYLGKHYGKLLNAQKALPKDKQSQSFATGELVKLVIDNTLRSIPFGNKYWHETIPRVLTLWMELGSHCIKKEPRESAEMFDKRIKTLQVTNKQLQKYFERVPPYVFYHALPQLISRITHPHPEVWKQLCNILTRIASSHPSQALWSILGVVRSADRTRIERGTEVLNKLRDPKTKPKNLDVHGDLKTLIHQGQRLCDGLLQASEAPVEPRAVKVKLGKDLGFNHKLAPSQLVVPVEATLTASSPATANSETIRRHRSFAQDKVTIQAFTDDVLVLNSLQRPRKITARGSDGKLYGLLCKPKDDLRKDQRLMEFNGIINRALKRNTESSKRRLYIKTYAVTPLSEESGTIEWVEGIKPIRDILLSLYGSKGIRPNYNEIKKDLDMASSAPEHAHIFGEKVLNQFPPSLHEWFTETYPEPDAWMAARLRYARSAAVMSMAGHILGLGDRHGENILLEEGTGGVFHVDFNCLFDKGLTFEKPELVPFRLTPNMVDAMGPYGYEGPFRKSCELTLSLLRQERDTLMTVLETFLYDPTTDFVGKKKRSTAGVPETPAEILESVSTKLKGLLRGESIVLSTEGYVDALIQEAVSHFNLASMYIGWCSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URS2</accession>
    <name>A0A9Q8URS2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-histone chromosomal protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764388.1">
        <property type="nucleotide sequence ID" value="XM_047909772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URS2"/>
    <dbReference type="GeneID" id="71990502"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10624"/>
    <dbReference type="OMA" id="MKNMGGK"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01390">
        <property type="entry name" value="HMG-box_NHP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00057588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00067275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="108" mass="12101" checksum="459E2B86F0B70467" modified="2023-09-13" version="1">MPKEKATTRGSKKAVDKSAGGKKKKDPNMPKRGLSAYMFFANEQRDKVRDDNPGIKFGEVGKQLGERWKALSEKQKAPYEAKAAADKKRYEEEKAAYTAGGDEEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USB6</accession>
    <name>A0A9Q8USB6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS-type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764971.1">
        <property type="nucleotide sequence ID" value="XM_047910021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8USB6"/>
    <dbReference type="GeneID" id="71990751"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10873"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF37">
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <name>thiamine diphosphate</name>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="THDP-binding"/>
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        <property type="entry name" value="Transketo_C/PFOR_II"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273:SF0">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal" evidence="7">
        <location>
            <begin position="41"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal" evidence="6">
        <location>
            <begin position="620"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="824" mass="93210" checksum="A299DD762F5F7B6C" modified="2023-09-13" version="1">MASDIALRTTKPPAHDQGLDDEAKQWSVYTETRSTIGENPLSPDELDKTKRYMNATLYLCLGMLYLKENPLLREALKKEHIKPRLLGHWGSAAGQSFTYIHMNRLIKKYRLDAFVISGPGHGAPGLISNFYLEGVYSEVYPNKSEDVEGLQRFFKQFSFPGGVGSHMTPETPGSIHEGGELGYSLSHAFGAVFDNPNTIALTIVGDGESETGPLATSWHSNKFLNPIKDGAVLPVLHLNGYKINNPTLLARVSHEELEALMKGYGYTPYFVEGHDLDSMHQAMAGTLEHCVNEIRKFQKQARDSGKVFRPRWPMIVLRSPKGWTAPREVEGHYLEGFWRAHQVPLTKVLTDDTQLKALDQWMRAYGPDKLFDESGKLVPELRELAPPKGKRMGENPITNGGSIRKPLRMPRFQDYEIKVDKPAVSYGPSMANFAKFLRDVMKNNMDNFRVFGPDETESNKLSAIYEAGKKIWVNGYLKEDEDGGNLDPNGRVMEMLSEHTVEGWLEGYTLSGRHGLLNSYEPFIHIIDSMVNQHAKWLEKCAEVSWREAVSSLNILLTSTVWRQDHNGFTHQDPGFLDVLCNKSPEIVRIYLPPDGNCLLSTMDHCLKSTNYVNCIVADKQVHPQYLSMDAAIEHCTKGLGIWDWASNDAGQEPDVVMASCGDVVTQEALAATALLRQYLPELKIRFVNVVDLFKLIPNGYHPHGLTDREYGAIFTTDKPVVFNFHSYPWLVHRLTYNRKGQERMHVRGYKEKGNIDTPLELAIRNEADRFSLAVRAIDSLEEVLGNKGAAAREKLIEQRIRSTNYTYETGLDPEEFTDWKWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUL6</accession>
    <name>A0A9Q8UUL6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_12253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767298.1">
        <property type="nucleotide sequence ID" value="XM_047911401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUL6"/>
    <dbReference type="GeneID" id="71992131"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12253"/>
    <dbReference type="OMA" id="CQGVTQG"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.960:FF:000005">
        <property type="entry name" value="6,7-dimethyl-8-ribityllumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO22932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="208" mass="22082" checksum="A151BD717EC83351" modified="2023-09-13" version="1">MTTLKGPGEAKAYDGSNLRIGIIHARWNTKIIDALIAGTKKSLTAAGVKDENIILQSVPGSYELPYATQQMIQAGQTQQTRAGVLLQSATDLLSSSTADLSLEGKKDKDPPSTRSFDAVISIGALIKGSTMHFEYISDAVSHALMKVQMDTGCPVIFGLLTLLTEEQGLERAGIDEAGKGHNHGEDWGAAAVELGVKKRGWAGGEFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UVI4</accession>
    <name>A0A9Q8UVI4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768301.1">
        <property type="nucleotide sequence ID" value="XM_047911688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UVI4"/>
    <dbReference type="GeneID" id="71992418"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12540"/>
    <dbReference type="OrthoDB" id="5397846at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF8">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="235" mass="26250" checksum="49D5BDD05ECDD125" modified="2023-09-13" version="1">MSLSKPCRLLAIPPELRNHIYSLLLSSSTTIRVTHEGITRPRPCKLVFPNEDPSHQTTNIIATNRQVQQEAAAILYGNNTFLFVSTRALTVFLAHVSRSARCLRSVTLDALDCERDVLRFSANMLTQVTALSCLTIRVSRYYPDEAPEIASDLLPLVRTLYNARMQSKITDILEIIKIVPDGEETQLVRIDVKTAVGIELSTSKDQKFKAWVDDIKTHLAEIVADENGDGVVSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW68</accession>
    <name>A0A9Q8UW68_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_13702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769067.1">
        <property type="nucleotide sequence ID" value="XM_047912850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW68"/>
    <dbReference type="GeneID" id="71993580"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13702"/>
    <dbReference type="OrthoDB" id="10664658at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO24701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="121" mass="13880" checksum="1CE7974865970E7B" modified="2023-09-13" version="1">MPRLTRHTEATRQVMDSTAVSRVLATAELLEMILVQLSTSDGAQSFWYAREQVADNIMQLFSAQRVNVFFRNTIRGSMKLRRLMWLEQDPSVQEPETTGAHHLSNTNPIVESFFFGTTKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UW73</accession>
    <name>A0A9Q8UW73_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">N,O-diacetylmuramidase</fullName>
            <ecNumber evidence="4">3.2.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Lysozyme CH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_13902</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769110.1">
        <property type="nucleotide sequence ID" value="XM_047913050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UW73"/>
    <dbReference type="GeneID" id="71993780"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13902"/>
    <dbReference type="OrthoDB" id="6590422at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000060">
        <property type="entry name" value="Lysozyme M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135:SF2">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="7" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040429152" description="N,O-diacetylmuramidase" evidence="14">
        <location>
            <begin position="18"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO24744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="220" mass="23769" checksum="804D7C257D2AF60F" modified="2023-09-13" version="1">MKLTNILPATLALSASAAPLEERASSVQGFDISHYQTSVNFASAYSGGLRFVIIKATEGTTYKDPSFSSHYNGATSAGFIRAGYHYASGTGDGSQEAKFFLANGGGWSNDGRTLPGMLDLEGPCKSVSWIRTFSNTYHTATGRYPLLYSSPSWWQSCTGNSNAFVQTNPLVMACYNAQPCTPQGSWPYYTIWQYKDANAYGGDSDVFNGDMTQLKKLATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWD0</accession>
    <name>A0A9Q8UWD0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_14408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO24878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769244.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWD0"/>
    <dbReference type="GeneID" id="71994286"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14408"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="64653" checksum="5558C2D139F85D5E" modified="2023-09-13" version="1">MLNTTLTLDRTFPGPGPNALIDSDSMPSLQRSGTEDGNLRGARAAVTEARIKMRIPCDGTGCRCRSGCKTATCKCRKSEMECRPDCKCFGPDHDCFKCENPYNNLLDLFGGECTSRSLFSDAIHKYTGHTPNACFKLWLKQRSNLENGVVDIEKLEEKISADCDAFKQDVELRAWRDERNRIEEGLAHENVDGNEIEEDLAHDDDDEYDEEYLEWCEEYNMQLLRVYALSTSRPRGEAAEVTDDNVPHIWSFCCDRWVDANRIRHCEDCDNCFEDAWHCARCKKCVVGRKLACMECGGVPRAGIDEQAASKAHTAKPANGRVPKRPRKSTVKERQMTEASVYAPDGIEKCTCDCEDSCKTAKCICREWGGGCKAGCSCRNADAQDSSAAVLPSGSSFNCWNPFNTVLPKFFGDGHDQWMANPCFTHFINRASPKAFNLTTGGLEKLLLKDKLPFEIFTPDELAAWNTKLPSLPAGSQERANHMQWFFRHVLGEKCDPSGSKHGAWWRWSFCIDGWNEGGNHHHCTECGECAYTKHVWHCTVCNKCRDNIFQPCKKCGGVSNMYEMGVEKPWLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWI0</accession>
    <name>A0A9Q8UWI0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_14212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769394.1">
        <property type="nucleotide sequence ID" value="XM_047913360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWI0"/>
    <dbReference type="GeneID" id="71994090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14212"/>
    <dbReference type="OrthoDB" id="3642406at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO25028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="215" mass="24923" checksum="AC5BA7CAD8A4D005" modified="2023-09-13" version="1">MSQTTFTTPRIVHNMRSTEVFAYPACGGHVRKTVSRVELDWIGLTVVSGDELSDESTPIAVNKDRAHRDHHAEDAFALRLMQIGGRWWPSQKFYRHHRTSDYPYGYHYPPDLDVGITSEGGILILRTRGEDYKFIHMPDDVPMKPDTWSRLRLCSSMRERCSVLRAFGAMAYTSMHNCPELPSILEEGIAESWRYEELMNRMDSTEYLDWWLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXV2</accession>
    <name>A0A1P8YXV2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_13362</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">0WU</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="KX943181">
        <property type="protein sequence ID" value="AQA29352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768285.1">
        <property type="nucleotide sequence ID" value="XM_047912510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1P8YXV2"/>
    <dbReference type="ESTHER" id="pasfu-a0a1p8yxv2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="71993240"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13362"/>
    <dbReference type="OMA" id="YRLAMTI"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004104">
        <property type="term" value="F:cholinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000997">
        <property type="entry name" value="Cholinesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00878">
        <property type="entry name" value="CHOLNESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041001951" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="22"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="4">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600997-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQA29352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO23919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="533" mass="56362" checksum="04FC3CCFF38187B1" modified="2017-04-12" version="1">MQSLLLTTACLMRLSGLVSATSPSVQIGAGTYVGTLTSVRASAPTANAYLGIPFAKPPVRFMPPVEALPVVGEFQATSWPPACIQQSLGFVEYNNTDAANLLTSTYNTKESEDCLYLNIFTPTNATKSSKLPVMFEIYGGNLQGGGSSLPIYNGASLAAEEDVVVVTIGYRVGPFGFVPSEEVDSTLRNPGFLDQRLALEWVHHNVEHFGGDSSRVTILGQSAGGYSVKQLWANPPNPLRFHAAIMESEGLLLTRNDWPNLVANLNCSAAPSPLECVRALPVGAVKDASLRDATGAMATNAFSILSFPPTVDYLTNTNRSEVAVATGKAARIPILIGSNGNESAALANGLNAATAAVAIPLLLNSTAVSTLFPTWYSSALAQGAQSEEQAVSKIVNNVVFNCPISILSQTASASDYSVWRYLYNATFADLNTYPDQIKYGAYHGAEVTSVFGVYPSGEDEAAQQALARYVQGIWAGFARTLGGSVPWAKVDTEVDSVFRIGQDNVANGSTIYSGVVDGECGLYDGYVLSAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L4K4</accession>
    <name>A0A9Q8L4K4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium- and chloride-dependent GABA transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_00189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755142.1">
        <property type="nucleotide sequence ID" value="XM_047899337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L4K4"/>
    <dbReference type="GeneID" id="71980067"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00189"/>
    <dbReference type="OMA" id="FNNINHR"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11554">
        <property type="entry name" value="SLC6sbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="584"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="656"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO10776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="671" mass="73554" checksum="3BA32BFB6C657317" modified="2023-09-13" version="1">MNLLRKAGSFFAPEAKKSEDSRDQWPSRASFVLASMGGCAGMGNLLRYPSVVFNNYGLQRFIPYLMAILIIAIPVLILEIAIGVAYRGGSVVAYNAMYYRFKGTGLGLLFIGFFIGHYFVIILAWIMTYFRYSFRSPLPWEGNGQAFYMDTVVANPQPIVGSLSPDGSTVLGYTEYPAVGLVGETVGWVAFTWFLVWLCIFRGVGLTSRVVYFTMGIPIFITIVLIGRGVSLPSAVDGIRLYFARWRGETLASGQIWQAACGQVFFSTDVGFGYFTSYASYNTNDSNAVMDSIIICCSNALFDTLAAFAVFGAIGFVGLMPESGVRLGTFTVGFLTLPEAVTEMPGAQFWAAILFLCLMVLGFSSSFAMLDAVVTMIMDAQGAVASLKRPAVVTILVVVSFLLGLPYSTQFGYYLLEGIDRWINDVALIFVVWAEIVSATTIYRWKDVTDQVGMSAFVSYNAAYFGGIILGPAIGHAVSPPAGAGVGFGIFIIGTAIAILIAKTPDAKAARFWGNNAHTSRAWYLAFNSGNQLPRDLNVVVGTGKNWTILWFWTLLMRYISAPILAIVYSFAYPSFYQLRYDPLHIAGFTLAHFVLVIIVLGFIVPRWYAVFVPPSRRDEGKERTTANVSSFLLDSAEVQSQEEGRVSSEEESESEEKKADGVGHDEQVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L574</accession>
    <name>A0A9Q8L574_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Guanine nucleotide-binding protein alpha-2 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CLAFUR5_01199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755442.1">
        <property type="nucleotide sequence ID" value="XM_047900347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L574"/>
    <dbReference type="GeneID" id="71981077"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01199"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000009">
        <property type="entry name" value="Guanine nucleotide-binding protein G(O) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000469">
        <property type="entry name" value="Gprotein_alpha_12/13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00440">
        <property type="entry name" value="GPROTEINA12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="178"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="203"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00074402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="UJO11076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="358" mass="41086" checksum="FD56FA2DB39D5A83" modified="2023-09-13" version="1">MVIMCFGSSSKEDPEAKKSKAIEKQLREDQKRMAKEVKLLLLGAGESGKSTVLKQMRLIHTKGFSTQERKQWKVTIFQNLLHAFQVVFGAMEEQEVDFADNDNIRFAEIVAADPDIGVDEPMPLDCLNAFRSLWEDQGVQAAIKKGNEYALHDNLTYYFSEIERLFAKDYLPTDQDILRARLRTTGISETIFETGNLTYRMFDVGGQRSERKKWIHVFDNVQVVLFLVAISGFDHVLVEDRNGNQMHEALMLFESIANSKYFEKSALILFLNKIDLFNEKVETGAARIADHFPDYTGNDRDTEAGAQFFAKKFRNLVRDPDKDAYVHFTNATDTNLLDKTMKSVQDMIVQRNLHNLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L5S8</accession>
    <name>A0A9Q8L5S8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755724.1">
        <property type="nucleotide sequence ID" value="XM_047899486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L5S8"/>
    <dbReference type="GeneID" id="71980216"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00338"/>
    <dbReference type="OMA" id="NMVDTQE"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="428"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="850" mass="93943" checksum="484880A4678F8C99" modified="2023-09-13" version="1">MSNRPHISRPIPAPSTSSLPPLPPPPPPPAPPPPTEPVSQPEYQASEQIPWMATLSRPLSDIRELSEPSLMDNKMYRGGAKVRHGRTESQQGSSSKWNEPRNDSLQRQQSLKAMVKKVTKLSPGGLQPPDGPSSSYSSTLEQSSLYTIPQSSVPRRSSSQTYSQPQRQPKSMNRNPSLQKKTNAPALASNKGFSIPNHGASQSPVKEAGLRLDPITADKARRIPSQTHVRSPHPTDILDFPSYRHPRVKLELQISAPVFVGGGSVEGYVRVIVDDNQQVKKRHSLGIAALSVDLLGFEEVDDSRRSTFLALGTELIDSNHPPPPIMAQASSAVFVADKFWSMLPSCSALPFMISLPLDTGNPTFQSKHASIRFLLSTTALIKDSNKHYRVRTSQDINVIPTYDPERALMSLPSPLTASDEVNIPRSAGAESVKLTAGLHRQVWVSGSSIFVDVHIANKHRKPIKRLELTLERDILSYRHAAPAAYGRLASQDRIFDDKERTVLARSTFKAGTVGWHGVEAHTSDTRTCELELPRGHANIRCGKYFEVRYFLNIAASLSTAKSISVQLPIVLIHMNSLDVVPNSVAQVAAAIEEKRVHRRLSGSRPRKDGVHSRQRSLSSPARTTDVGHQHSYAQGRAFAAPRQQSLDRQKEYRAEMDDIRHVLDKSPRKHPPQSKQAFSIRKMTSDLSLLSLRLAELSADTLGVFGDISYQTPPTNRGGHNFEEAPGLRDRLKRIGSLDSVRSKKSALAERAKRFNDQNIKPKLAMANQSNLAPHALGLTTSTRQVSSDMPSERSTSALSFRDKLDRSRFEFQAVRRKASGNLKQRSVEWLEQKLPNGGGRRDVGAVGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6P2</accession>
    <name>A0A9Q8L6P2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756168.1">
        <property type="nucleotide sequence ID" value="XM_047900760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6P2"/>
    <dbReference type="GeneID" id="71981490"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01612"/>
    <dbReference type="OrthoDB" id="4150019at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO11802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="427" mass="46423" checksum="D683D410FA0912B1" modified="2023-09-13" version="1">MSSSDSSQHDPSPTTTRLSSYAVTAPQEHLTSARANAPSASGTPLSERKKGRPSKAKAGEQLSSKSFLTPQLRGPIMSESELDKKRNKLGYQRISIACAHCRRRKIRCLLSEDDSEPRCQNCIRLKKECVFYPVDQQNALDARSDASSRTGEPSAPSSAASTSPSHPSIRSFDQQSHQFGGGYHHAPSDAAGGYGIPISPIPALPSQGGYVPQSYGYLPQREPPTAWNSHQQQLSSHNQLTPVSTTSSIAPPFTRYETSNNAVDTAPFPGSSDQQPPAISHHSTGYSYTPEPMQQQWQPPQQHNVQQPVHRSISYPDYSSQNPYPQGFPSTHQQPSAFMQHAAVQPHQSGPRAIGLPSQALPPTGHQYAYQMPPDQRSSSIPAMAAYQPPATQMQQDWYPEGAYGPGGSNARGHDLNPHGGYARRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6T0</accession>
    <name>A0A9Q8L6T0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic dynein 1 intermediate chain 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756197.1">
        <property type="nucleotide sequence ID" value="XM_047900099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L6T0"/>
    <dbReference type="GeneID" id="71980829"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00951"/>
    <dbReference type="OMA" id="MHDRPEY"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="496"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="675" mass="74732" checksum="DDD99D172EBC994D" modified="2023-09-13" version="1">MSSIQQRKDEILAKKAKLAELKRQRELRQKDFTTNRQSLDAPELVAPSPRSSSATKREDIESLISSLVDRPSSTTPGTPTNKKRSSRIDQSSDDASTPSVTYQDASTEPQTLSFASLTTVYEIHVESKPEVISYSKGVQTEQHWQPDPDSEDSGEVNSADRSPSRRRRKLSQRERELEEEQIRQKLRQEIEEELKALKLDEAAQPERERFPARALAPEELSAVISSNDLLDFVERSSKVIERALDEEYDVLADYALQSREVEDDEYVGRRGRRVKEVAQFDLDDVMGGKRIISDIDFSPKFPELFCTAYTKSARSPHTPPGLLNVWNMHLKGRPEYSLHATSDLLSCQFHPYHPSLILGGTYSGQLCLWDTRARNQRTGEPVQKTPLTGGRTGHAHPIYSLSVVGTQNASSVVSVSTDGVVCAWSTDILTQPQEYLELHAPNPSAYKTDDVAPSCISFPASDPTYFLAGTEQGSIFPVHRYDRAGAKSGVDARTSYKGHEAPVTGIDFHPARGKIDLGDLFVSCGLDWSVKVWRARPPTTNSATISGNAEVIRPLVSIDRDDSVYDVKWSPTKPGIFGCVDGGGRLDIYDMNASSEVPVGGGRPSHVEKDVYSLKSLNKLAWEKSQGRHVAVGGLDGITTVFEVGSELGGVDTKQDSWVGVKKWVGRQTKTKVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7G7</accession>
    <name>A0A9Q8L7G7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_00647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756588.1">
        <property type="nucleotide sequence ID" value="XM_047899795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7G7"/>
    <dbReference type="GeneID" id="71980525"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00647"/>
    <dbReference type="OMA" id="CADSPSG"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000420">
        <property type="entry name" value="Yeast_PIR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00399">
        <property type="entry name" value="PIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50256">
        <property type="entry name" value="PIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040286895" evidence="3">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="203" mass="19575" checksum="DCE33D20A36F517D" modified="2023-09-13" version="1">MRSAIFHVLAIAGTVYAADAPAAYGEASTAEEYPGAVTQIDDGQIQAPTGSYDLPSPTTSAVVETSAVETTSAVEAPPAYSSVEISSSTEAAPVSSASASSVPVPVVAVTSAPAVTTSVSVVTTAPVVANSTAPYPTGSGNTTTLATSASTITTTESKSASSTEADAVGGSTSPAAATQTGAATAIQFSAGFAAIAGLFAFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7S5</accession>
    <name>A0A9Q8L7S5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc-responsive transcriptional regulator ZAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_00563</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756736.1">
        <property type="nucleotide sequence ID" value="XM_047899711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L7S5"/>
    <dbReference type="GeneID" id="71980441"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00563"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="182"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO12370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="503" mass="55325" checksum="A8B14602399D6237" modified="2023-09-13" version="1">MTRFEESALRNSASDQQSSSSTLPYWHPSSQFSSLIDPQHDASIPHTASENGHPGSFPAYTDEQSSVPLQTSMDFELSRQMGYSQFNDFAPAVAQPLSQADLSSPDPSVSGMSNYSQGLSIKTPGSTRSMRRPGLAGAPALTNGHYCCQWSVNGVTCRHKFMDAKALNDHIRAQHVRGAGTFMCHWSGCDKGSFPTANKLVRHVHSHTGYKPFPCSCCPQAFVTKDQLDKHLTTHTGAKDFVCTWPGCGRSFAVKHALDGHVNSVHLKAKKHICPCCAQAFDDSSNLSKHKKQVHNTDTGIKCPARHTHGCMYVDSRKDKMKEHCERKCHGLETVTDAHAWNLWVQQFKTASRKTDSRRQSLLRSTASTPSYMPAPYRTGSIECSKQGCNIPVCLPCNILCNDVHSSHHDVPCHEADCDPHAPCDPCDPCDDPECEEAAWQPCTTQPCNLPHCGSTSVSSTPSLPATPHIPPDTYFQYAGGDLDAEHPFQMGQRLSEYMFMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L7S6</accession>
    <name>A0A9Q8L7S6_PASFU</name>
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        <submittedName>
            <fullName evidence="4">Oxidoreductase NAD-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="71981019"/>
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    <dbReference type="OrthoDB" id="436496at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
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    </dbReference>
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        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
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        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
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        <property type="entry name" value="Oxidoreductase_NAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505:SF1">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
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        <location>
            <begin position="44"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="321" mass="35873" checksum="923879119DFF7F09" modified="2023-09-13" version="1">MPSIARRACLTRLMISPAVARRSMATVRSALPHEQRTQAEPRESVLEPVILANIKDVNDNIRLLRLNAVDAAHTIKFLPGQWIDTFIPGLTSAGGFTITSTPSQARPSNHYPPFLELAIQKSANPPAKWLWRPEDEILGSQLVVRVGGSFTYPPPRLDVRQVDRLVFVAGGVGINPLISIFSQLLRNHPSTRPREMHFLYATKADSELDTQKILFLPRLMDLVAAVADPNVTLSLFVTGTGDSGAIEHGRLPNRTFGRRLREEDLRSAIDGHKQNVFGAQHDRQRTLCYVCGPPSMTDEIVQFLSREEGMSEARVLCEKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L845</accession>
    <name>A0A9Q8L845_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_01018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757032.1">
        <property type="nucleotide sequence ID" value="XM_047900166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L845"/>
    <dbReference type="GeneID" id="71980896"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01018"/>
    <dbReference type="OrthoDB" id="4760831at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="118" mass="13232" checksum="D2140EB91D9757D9" modified="2023-09-13" version="1">MVLAELNISHAEGHLSIETNKTPFGTTSNRLASPIDSVVGDLPGIGNPRMQVVFDKTVCDALQLSCQYQEVNVLIIRWAEHLDRDLQCGAEVEELQKLFRDQFHFPTEVLELNDVKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8I0</accession>
    <name>A0A9Q8L8I0_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-mRNA splicing factor CLF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756509.1">
        <property type="nucleotide sequence ID" value="XM_047899632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8I0"/>
    <dbReference type="GeneID" id="71980362"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00484"/>
    <dbReference type="OMA" id="FQDQGME"/>
    <dbReference type="OrthoDB" id="5352000at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO12143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="850" mass="90388" checksum="B40F84BAD036011D" modified="2023-09-13" version="1">MSVPKPESSLTGHCAAIEKDTLYVFNADAFQSLPLKENATWSQEITGIPVQDPACVKATSNGGASLYVVGGATDNSFYMGLQRYSFDGGAWETLTPLADVMRSRTNHSVAYLKDSDSILVYGGSTPDAPSLLSSQTFLISTTLPYNIRSFTSNAPPANNPILQPWNSSHAVMVGGETTNTGVWLFGPNDGWTQLGTNLSEPLDSAARAVVIDGEDGSKVLQVYDFQTSPNTAQGVVLLGPGGEVAAPGTTVGDSNSSRKRKGDLSINNWPSYNSTNAPTSTRTDCSISRNAQGTIVMAGGNDNDPIAMYDQNENSWIDAGDFFNRQVQQPLQPSKTASTSPTSAESSVSATSSEAAKGGGGSHEKTMRTLGITLGVLCGIAALFIIVLLFLRWRKMKAKKKNGGYLEEKDGQQNPDRMSFADRGASFMKEAGLSTDELAPPNRNLYNSSPGSHSSLAIIAGKIGNKRGTNGFQAHAAKGSFESTTHLVRDKDGNLVHAENHEMMDIGDKSATLASSTLTVPGAVHGSSLDKETLTHRKRSSGWSKYFATSAPTGPNGTSHIPSVYVKPSQSTLSMGSEYSVDRAPSQVSRIPSSVLVPPLDIDFNKTVDGQRLSHVTQGSPAFFDSREDFARGGSLDVQGEGQRGIIVDSNDPRTSQATSIGSSWGNRSTIDSTTTSEFYNESHTPWTPMSGQDAPRGTSSVYTNSIYDAGRRVPSRGKSAGFFPGSGTNFKPSKVKLSHAAGPTSQWASPQPDAQTADMDWAKPPKMPAAKAEAATSNDRDSTMTVFPGADYLDDKDDGAQAKTAQAIAGAQKPSQRQSYGRRHSTRQSRQSQPAVNTDMSWLDLGSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L8N8</accession>
    <name>A0A9Q8L8N8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_00920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757125.1">
        <property type="nucleotide sequence ID" value="XM_047900068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8L8N8"/>
    <dbReference type="GeneID" id="71980798"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00920"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO12759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="180" mass="20990" checksum="0BB364E641860A09" modified="2023-09-13" version="1">MVCSRVYRSNPTLLWSLDRLQAPERITHTQRFAKTEAQRPFVLALSPLEDKIASNFPKLLHNLRIPRRKCCFGYQGLLIKLDLASEVQHSWDNTERLNQWLTEKRDLYEDYKHQSGEHDGPQKIVLVWLIAKDIFQRLDRDITFEEISIADRGDSVLTVPQEDSVDDASTQDIRAPVFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB63</accession>
    <name>A0A9Q8LB63_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758545.1">
        <property type="nucleotide sequence ID" value="XM_047902360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB63"/>
    <dbReference type="GeneID" id="71983090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03212"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="443" mass="48180" checksum="168C43F4ACFC0682" modified="2023-09-13" version="1">MAKYKHVRTRGKPRISVLRSNLATTNWSLCPSTEDDIEPFLAATAAALESEPAEHFSRLTIAPLDNKLGSCTAVIPVLDPLAGKSATKSEQKLLVFLQEAGVLSPAAGLEELSQWGQANELPYRNDLRREARGLYSNEVTKEILPGVSVTVTQYEGSLAHAAAQAVPPSIAGGSGALEPLGKNEQKFLRHLKQTRALPQTATAAGLHLWCRSRGLYRRVDVQCAAKAFQKANVSSIPQQQMGAQATIHHGKSARVEKDTARKADNSAAGTGTHRLNADDLLAWLQRGGSMTGSGTGNTMSLPRPDPKMESTSRASIRQHTSMFSPEQKVNIAIPGLAERLTERAGFHAMASEQPRNSNEDAKDQHGLTAINVNHSTGASIHDATQVVGQEEFRRRTDEEQLQSLKRRSLIAQNANSEDLWRWKVTDVATGEAWREALKRGVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LB95</accession>
    <name>A0A9Q8LB95_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MYND-type zinc finger protein samB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Suppressor of anucleate metulae protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_02792</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MUB1/samB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758552.1">
        <property type="nucleotide sequence ID" value="XM_047901940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LB95"/>
    <dbReference type="GeneID" id="71982670"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02792"/>
    <dbReference type="OrthoDB" id="5594178at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990304">
        <property type="term" value="C:MUB1-RAD6-UBR2 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.140.2220:FF:000003">
        <property type="entry name" value="MYND-type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051664">
        <property type="entry name" value="MYND-type_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442:SF1">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="12">
        <location>
            <begin position="583"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="130"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="275"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="633"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="641"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="663" mass="73386" checksum="B3706CFC95BF607B" modified="2023-09-13" version="1">MREVNFSIPNANKASVGITTALYDRRALDCTSTLPLINSLNNLAYLTTSSGRIRDILTVDGGIERLVCILKEGRSKDMMEMWKWNLAFQCIVNIGVRGSEAVRTRVVEADMVPVIATILDNYFKVMDKTKGRTEPSESKSKCPILRSFSRSANRTETADNRSSRSRRHAPPPISIPDSIPQPDADEPVSETTPTANTAALSLSSPPQRTVFRRSHSHHDSLGGRSQFSSPALQDTRQQRPPTSSATLQSNAGPVFVPPVRDIDRLPSMIPQLHAELSSQPQSPTTPGAPVQRPGSPRAAASAMRPRRRPSIRHQLSISGSDDDGQIEESVSDESNGPDAEPVVGIQADIVMQDIVDDDGLLESPGNGIAVPDVSSTDDETFSITHRSAADGSTVNPAATPTQGQMTLPQTQLPPPVNAVNATPPNLSAATWYPSRGLPFDRTATSVLAAMPRDEDVLMSLQLLAYVSKYCNLRSYFQQSRLVSRLQIGNELSMLDTNNTSGASTSKTQEELDEEWDNEFVKTPGETPYNIFPLIEKFTAKQSSSRHSGSSPSQQGDMQYWAGVVMRNLCRKDDSRGGIRQCAYWQCGKWEEYTRQFAKCRRCRRTKYCSKECQKGAWGSHRFWCVAAEDTTRDGDPGSSERHHHRQHRSHHHHHHHHHHSRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBD5</accession>
    <name>A0A9Q8LBD5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_02957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758650.1">
        <property type="nucleotide sequence ID" value="XM_047902105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBD5"/>
    <dbReference type="GeneID" id="71982835"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02957"/>
    <dbReference type="OMA" id="PQRAYKN"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO14284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="437" mass="48288" checksum="6756BA62640A3C53" modified="2023-09-13" version="1">MAPSSKAVTMTVASGTISKLDTKQTLKASTALLRKIQTDEASSKETSKANLLEDADGDEPEDETPVWMVLTTKKHIADKKRLKPGKIVLPHPYLDAEQENLKICLITADPQRKYKDLISEPGFPLELGKRIGRVIGMEKLKSKYKSYESKRQLLGEYDVFLADDRVITYLPTVLGKTFYKSGTKRPIPITLEGKRQTVDEQGNKRRRLAEGGSKVTKDEVKPKDAAHEITRTLGCTLVHLAPSTTTAVKVGIASQTPEQIQANVEAVMDAMVERYVPQKWKNIRAVHIKGPDTAALPIYLTDELWADEQDVLEEAPKANVGKKRKRGALTEASENEVLEVPGPDGKMRTLEKPASKKKSLELDVAPKKKRKSEEVDEEAEAKVAEKAEKKARKEALKAQKDSLREDVATESPKSKRKATADPPAPAKKAGKKAKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC45</accession>
    <name>A0A9Q8LC45_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_07842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759017.1">
        <property type="nucleotide sequence ID" value="XM_047906990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC45"/>
    <dbReference type="GeneID" id="71987720"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07842"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23365" checksum="2290ACB891A0A784" modified="2023-09-13" version="1">MECNAQDDSHMMDEGPHFDLNEEGEIVLVPPKKRERPRTEKRRRNKHLVALKGAGILPRDANHQDLQEWQARIGNDTTAAVHAAVEEVRKTHARQYPSPMVRRSQRLQTDHTAEALADSFDDPQDPMYGYLQQRAEALQRERDSKPTFESMAARARAGPSRDQVRAYDEGKQEEAKLARAEMKMQRGACLVTSGVLVALAMVGAGAPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC51</accession>
    <name>A0A9Q8LC51_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thymidylate synthase</fullName>
            <ecNumber evidence="2">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_08457</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759069.1">
        <property type="nucleotide sequence ID" value="XM_047907605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LC51"/>
    <dbReference type="GeneID" id="71988335"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08457"/>
    <dbReference type="OMA" id="AYGRFWR"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000013">
        <property type="entry name" value="Thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate synthase/dCMP hydroxymethylase" evidence="9">
        <location>
            <begin position="37"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO14703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="338" mass="38089" checksum="E32CAA35A693B400" modified="2023-09-13" version="1">MSRPNGLENEPAQAQSTTTTSGQVVQPSITTPHEEFQYLNLIRNILDNGEHRPDRTGTGTLSIPFPAQHKYTLSRPDGSLILPLLTTKRVFLRAVLAELLWFVAGDTNAKTLQDQNVHIWDGNGSREYLDSVGLGHREVGDLGPVYGFQWRHFGAEYKTCHDDYIGQGRDQLAEVIHKLKNDPYDRRIILSAWNPADLKKMALPPCHMFAQFYVSFPPSAPTRTDGTKRGTLHTLLYQRSNDMGLGVPFNIASYALLTHMIARATDLLPGSLTHTMGDAHVYLDHRQALEVQLTRQPKDFPTLEIKREIDCSIDGWMPEDFDVLAYEPHGKIDMKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC90</accession>
    <name>A0A9Q8LC90_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="16">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CLAFUR5_08434</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="16">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="16"/>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO14757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759123.1">
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</entry>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            </authorList>
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        </location>
    </feature>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="UJO15055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="19770" checksum="F230F90D3B245044" modified="2023-09-13" version="1">MCSIEPSHKTSGFQHQHRRNHQPHITTMCQICSIKEAAAKERWPKPVEASKKDLIFLVDSIHTEYIQYNNVKRSTPNAPPPDALLDLCRMLSDQLDALEVDREAWWTSPEKRAMRQRLEADLDQKRLSALHKINNSCIESIEGLSAKLGGFVKWSLNMNGGVWELMNGHKVAGA</sequence>
</entry>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="71" mass="7935" checksum="A0F88354AC459D01" modified="2023-09-13" version="1">MGLSDSIIILLVILAAAVSVAIGWAIYSLFHRRQGDLAMSDSGEQAEYMREVRLRERHLIAAAIGYRFDKV</sequence>
</entry>
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    <accession>A0A9Q8LEE6</accession>
    <name>A0A9Q8LEE6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="5499"/>
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            <taxon>Fulvia</taxon>
        </lineage>
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    <reference evidence="1" key="1">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8LEE6"/>
    <dbReference type="GeneID" id="71983899"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04021"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="160" mass="16452" checksum="A01116895A1266BE" modified="2023-09-13" version="1">MAQMSSPHSPTIQPLHTLTNNHQQANMKVSTIIASAAVTKRATEHGELTCHAGGIGACGWAIAPGEVAISYNDLFALQTPNDNPLCGKTIQATAGGVTKTVATAAVPASAAISPSLRSTSTPSASPPPWVACQSTGRTLSESKVKHPRLLLIISVHLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEU0</accession>
    <name>A0A9Q8LEU0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO15924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760290.1">
        <property type="nucleotide sequence ID" value="XM_047903333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEU0"/>
    <dbReference type="GeneID" id="71984063"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04185"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO15924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="206" mass="22413" checksum="E22CAF3C42039834" modified="2023-09-13" version="1">MYNAMPSNGTNSTAAIIEASVAGAEHILTLSGYAMYTVSMIGQDRSRVHFNVIDSDGAAELQNEVMQDVYGFAGTTSNAVGQQVVIPASIWRTLIADRDSNGRKPVADPVATDFLTRGDLRNVFLTTISGRKLFITTEGNFGIGPYSMNIGDLICLFPGAQVPFVLRQKPDVFPERFELVGECYCHSLMSGAKPGETRTLRKFHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGV8</accession>
    <name>A0A9Q8LGV8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_06430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761575.1">
        <property type="nucleotide sequence ID" value="XM_047905578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGV8"/>
    <dbReference type="GeneID" id="71986308"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06430"/>
    <dbReference type="OrthoDB" id="5363290at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO17209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28872" checksum="4A010E491E53C383" modified="2023-09-13" version="1">MAAATADLTPLHLRARAARHWQQNRMSGYSLRLTCRILQLISAIIILAIYSIDLQHFTTTNNRAPASFAFAEVSAGLSISLCTVHFWWILRSTWWCIPEFMLAVLWAAQAGVFGMIYLSDTTTLDEEDKARLGRMKAGIAFGLISMILWLVSFVQSLVWGCQRRKTKAGIKREVSFQRALEGLKEQRMVESVESSRYEPVENDVEQERKRTGSEGGDADVQDAVQPPAYQAVVHDVLPSPERCQLEVLTKWQGRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGY5</accession>
    <name>A0A9Q8LGY5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761666.1">
        <property type="nucleotide sequence ID" value="XM_047904833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LGY5"/>
    <dbReference type="GeneID" id="71985563"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05685"/>
    <dbReference type="OrthoDB" id="3646183at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="756" mass="83405" checksum="530956B7696F37B2" modified="2023-09-13" version="1">MSTGSPGHDEIDGGQRPAKRRRVALAWRPCRERKSRCNGGHPTCETCMQQGSECSYPPQISKSDLLRQEVSCTIESLEERMAGMERVLATIAGNQAVPPAAAARLVATNATTQRESSGEITIHEDALQCTLERDPETDGIGIVPSTSREDAFFGPSSNIAFVRLVSRALSKVNEQQNPNGKTQTNDASGGHTRNNQIPPSTKEQEPSAGGFHPRRPGDAPRTFSVPHDSKARELIRGFFLNCGHVHPYIHEGRFMQSYEQARRSNFTEIRRSWLALLYVLFAIAAQSWPYFESPYAVHNAEAATYYNLGFGLCLEQVFNGSGPSIEVVQCLIAISLYLQGTYSSSASWMFHGIAIRLAYQLGLHSGGPPKSMDPIECEVRVRVWFGVLLLDRTMSMTHGRPSQILELRSAVRRPQVYLDPAQRGMQQQDESSVAFFNAMIDLYEFLYKTIEDLYGKNGGGRTSFTLKTIAKVYTLEGDLAQWTSDLVPQLSILTSSELAKQPMHLNEPVALLIRRQRTVITLRFHNARILVHRPVLEGLMDLYLATDPDPQHAESMSKAGANCVALAMSSAVECVEIVHHLIAGSTHGHQQLGAWWFSIYYTFNACLAILAGLAVSQPGTASAELLTKQEQDAAFKALQQSLEVLDCMDPSGEGPSTVTRCRDYLKELVSIAEPMRIGMVVTRDAISTAFTNGAYDTSYDPAMVSTLPMTASSMGYMAPSSLFRQFSSNADLESFLFPVDMQSFGGHLMGFDQPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH13</accession>
    <name>A0A9Q8LH13_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761596.1">
        <property type="nucleotide sequence ID" value="XM_047904547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH13"/>
    <dbReference type="GeneID" id="71985277"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05399"/>
    <dbReference type="OMA" id="YANNALH"/>
    <dbReference type="OrthoDB" id="3426753at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="16651" checksum="3DDD0370515DEB01" modified="2023-09-13" version="1">MYGMVGRVDDGAGNVTGEITASVLPIGAASELVPAGTDGAHSVGRFSPPPSSSPLLTEFPKFLTNQYTVNTTSPAQSTLIMDAQATIQYANEARYGLYKVQTLGPLDVFGEDVIFGTFVASMQSEFRTGRGIVDVWRVLPNGRIDGEAILALLPPGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LH70</accession>
    <name>A0A9Q8LH70_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761686.1">
        <property type="nucleotide sequence ID" value="XM_047904811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LH70"/>
    <dbReference type="GeneID" id="71985541"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05663"/>
    <dbReference type="OrthoDB" id="5409186at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040448458" evidence="1">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="159" mass="16662" checksum="3E020DF25B433BA7" modified="2023-09-13" version="1">MKQHLTLLIVAAALTECRRTFGGPNGSIQALHNTLDVAKHLIFSHDLAKRQCRGNCVTCFGPGYQFCPGSGMDCYLPGDEDYGIEMCSNSEDGSSDTPSCASQYGPQYTECPDGVSCHDVSSSSSAACFRDDSAVEGCSGAREAGCGDELHGCDVAGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LHJ2</accession>
    <name>A0A9Q8LHJ2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_05451</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the VPS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761923.1">
        <property type="nucleotide sequence ID" value="XM_047904599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LHJ2"/>
    <dbReference type="GeneID" id="71985329"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05451"/>
    <dbReference type="OMA" id="FYLGTME"/>
    <dbReference type="OrthoDB" id="9976382at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030905">
        <property type="term" value="C:retromer, tubulation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06891">
        <property type="entry name" value="PX_Vps17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000046">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000034">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014461">
        <property type="entry name" value="Retromer_complex_Vps17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037907">
        <property type="entry name" value="Vps17_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011791">
        <property type="entry name" value="Vps17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="7">
        <location>
            <begin position="233"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="8">
        <location>
            <begin position="363"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO17557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="663" mass="74216" checksum="F59AC61061341AB1" modified="2023-09-13" version="1">MHVRNDARMSSSDQPQASSSGSSGKQPADRIQPNLRFQRRISERHYTEDSYRERTPVMEYPSGTSPWASSPEASRAGSSNDIPHEDLPGPAFAAGAIPESDDAASSAAHANGAHEHEGGWTPEQQHQWQQQQHQSQQHQQHQYQQHHQQGSQEENRRPAQSRYHNVPQQQRQHQPQYKLQAKITGLERAGKKDSILKFDVYVRNRFYVVRQAEQTKLTVHQTNLPKFRTTQFRDIRRTHSEFQKFASHLIGANPEALVPAVPPASTSAGLGTEEDDNRTKANMQRWLSVVCSNDVLMRDEEMVFFVESDFGYSPVARKKQPATGVRRKYLKQFQPPPDDTPELLESRPIVKSFYLGSMDAQQKVDKVVKHRRSLGVAESDLGIKIQALANNEMHTGLGNAYKKLGKVVQNTGDYHAAQGTAEATTLADPLAYHSSDAFIVKESLTNRHILLRELIQAQQTTRSKLTAADRLKASSSVKRDKVDEAISALDEARSHEAYLQQKTQRVTQNLLLEKRKWFMRTAAELRTGIREYVIREIEAERRTLATLEQVRPDVRAIDASGGLSRLGREAHPAARRTSMASSQGPKGDAWSGVPRRPDGLNRSISGSWPAVPEEGERSAETGDATGRRRATSGASSLGQLSEDDDDDRIDARNAASRLAQTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIK6</accession>
    <name>A0A9Q8LIK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc transporter ZIP9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CLAFUR5_05802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762521.1">
        <property type="nucleotide sequence ID" value="XM_047904950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIK6"/>
    <dbReference type="GeneID" id="71985680"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05802"/>
    <dbReference type="OrthoDB" id="19859at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040432238" evidence="9">
        <location>
            <begin position="20"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UJO18155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="428" mass="44879" checksum="9744546279987A93" modified="2023-09-13" version="1">MWDGLAILLLLSIVMGTASFLAGSLPLSFSLSQRQLRLITALGTGVLVGTSLIVIIPEGVETLYSASGSSHGHSERSLSLTTRGATVQPYLHAAAIEHQVRQETEPLAFPDQAIDNTFRTGPDDGFQTPKDASHAEPPSSDPGHEPGVVTQHPSDPSTEAEDSGHDPHAWIGISLILGFILMYLIDTLPRQASSSTAPQRFQVSLNNFSLNRTPSASNDVPSDPEAESFATNTPQHSSSRPSSTTVGLVIHAAADGIALGASSTGPSNHLSFVIFIALIIHKAPAAFGLTTVLLKQGLSKRMARARLIVFSLAAPVGALMTWSAVHILGFSSSSLGESASTEFATGVLLLFSGGTFLYVAMHTMQGNATDGHLHEAHMMNGYAGVPLDDAYAVQSPPSLKPATTAMVDTLVTVGGMLLPLLTQFGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIR0</accession>
    <name>A0A9Q8LIR0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxisomal membrane protein PEX17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761714.1">
        <property type="nucleotide sequence ID" value="XM_047905360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIR0"/>
    <dbReference type="GeneID" id="71986090"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06212"/>
    <dbReference type="OMA" id="LMVQWRQ"/>
    <dbReference type="OrthoDB" id="2357318at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26001">
        <property type="entry name" value="Pex8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="689" mass="76591" checksum="0D0E0353A13C857F" modified="2023-09-13" version="1">MPADRLLGTLLRALQTYTEQEDTPRLFGTASSLLTTLNNPLNVTLLTGQLLSAPAIWLRPEGLRTCMRCLSVFHTAAQALLKHEDALREKGPDQDLVNLQPERTLPKDEWIKAALSGADEHSPRWRHILVIAGLLLGFGRPEEENLSRNMRSTLETALITATNLALEETLEDDELGMASITLALNHCFPYLPDHERSQIDYDLLLPVLVRSTLHSSEGLQSAYFLGALDRDVLLQHDDHLQWSEQSTSYQQIQAMLSSPLIGSLGPLARLIGHSVEQANESWLVTAVLNDIETFARTLHTQWRQNKLSGVETTEQQLRLNERTLNITVPTLWRLLQSIMFASVIVLRSALGRLLGDIMLANDSTAPTIAKQSLYILRNLYFITTRQGSATFSQYNFVSYTAMDILGQYPLEAQSFLRDIRPAFVGTVAEHPLERNLDLFFLNTAEHFTLVLPPHVSEELLLPTVTCYLAAGGKGQLLPIFEAAHSVTLAVFSAPQNADATIKNLPLYVDSLFKVFPLNLSARQFRLAFKTLLKLTSPPSSLSLSQPMMPATLLELLHDRALHSSTTPIPVHPGTAEAAVEAPVPLSEQAVLTLTVLDGLTQVPLDLLDEWLPLTAEMIHMIQDAGMREHCKQHFWHILTGGELDPERSRVCHAWWSTGGGREWILYGSNEDDDTALMSGGFQGGQESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIU1</accession>
    <name>A0A9Q8LIU1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_05697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762285.1">
        <property type="nucleotide sequence ID" value="XM_047904845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LIU1"/>
    <dbReference type="GeneID" id="71985575"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05697"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF26">
        <property type="entry name" value="ADP-RIBOSE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="70"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO17919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="246" mass="27417" checksum="27D629D740E1BDE0" modified="2023-09-13" version="1">MRPIPAINRSLQIARHFSMSSTLRAAKIKRVGPLSPDEAKWTELRKIEWVDPAGKERVWEAAARKTRKESGIDAVAIAPIIRHPSRAPSTLVILQYRPPVDAICVEFPAGLIDAGETPEQAAIRELKEETGYEGKVRDISPILSSQPGMTNANMQVLDCSPTIVADPGFTNANMQMVTIEVNLKEGDEPPEQHLDDGEYIERVNVPLSELYDKLKALSKEDGKIVDARLFHWALGLHWSRRLNLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2Q8</accession>
    <name>A0A9Q8P2Q8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO10922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755288.1">
        <property type="nucleotide sequence ID" value="XM_047901407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2Q8"/>
    <dbReference type="GeneID" id="71982137"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02259"/>
    <dbReference type="OrthoDB" id="10679637at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO10922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="345" mass="39672" checksum="ACBE059FAE71BE58" modified="2023-09-13" version="1">MTMQKQASLLGLPGELRNQIYGYVAADIYHVQIRPGISVPRIINYEDQKRPSNKTAWYTRAAVIQCGPYDSIITCHTDHGMLTQYMNSSVLDRRMSDRPSSRSIPRRHPLLQTCRQLGEEFGSVLQSVCPEQLEVVVENFDFSQLLYQLEQYDHGSKAQDEIEESPQSCDIAIHLAKPTASLERIRQNLGFFAIHFQQPTDPNATRLDETKLYTTEDDDDLDISPSSGRTLHKNGITYKLYLRTDYAWHSKADYIKSIEHYATIEHALESVFDPGECYHPGMEWIHGPMGEHMTDCRAFLVEFDEDYEDDNASMRGMIERVKRTLDEDREKDLAAIVEGMPMLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2T1</accession>
    <name>A0A9Q8P2T1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CobW/HypB/UreG nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_01562</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755599.1">
        <property type="nucleotide sequence ID" value="XM_047900710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2T1"/>
    <dbReference type="GeneID" id="71981440"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01562"/>
    <dbReference type="OMA" id="KMRGDKP"/>
    <dbReference type="OrthoDB" id="10063137at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05540">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000208">
        <property type="entry name" value="Urease accessory protein UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715:SF0">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="7">
        <location>
            <begin position="52"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO11233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="253" mass="26993" checksum="B9919CF4B53C54BE" modified="2023-09-13" version="1">MASHSHSHEGQSHSHAAADHGHSHEILDGPGSFLGREMPIIEGRDWKARAFTIGIGGPVGSGKTALMLALCLALRDKHNIAAVTNDIFTREDCEFLTKHKALPAERIRAIETGGCPHAAVREDISANLAALTDLHREFNTQLLLIESGGDNLAANYSRELADFIIYVIDVSGGDKIPRKGGPGITQSDLLVINKTDLAELIGADLGVMERDSRKIREGGPTIFAQVKNGKGVDHIVDLILSAWRSCGAANGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3B8</accession>
    <name>A0A9Q8P3B8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755962.1">
        <property type="nucleotide sequence ID" value="XM_047900083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3B8"/>
    <dbReference type="GeneID" id="71980813"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00935"/>
    <dbReference type="OrthoDB" id="3628960at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="5"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="343" mass="37847" checksum="8300DD081943F761" modified="2023-09-13" version="1">MSRIITWYGLRYAAPPTGVKRWRAPNPIAQYGGYRSSCHTRCLVSRSNLFPTWLLPISTSIGGQEDGLTVDVLVPDKPAASKLPVFVEIHRGGYTTGSAPTTPGYAMVNQSKGNLIFVQVQYRLGAFGFLNSPEVRQDGTANAGLLDQRLAMDWAQKYIANFGGDPQRVTVHGGSAGGGSVTNQIILDSGASRPPFRYVIAEYPWWQPFHNETIISIQYNDLLAHSGCTNWSCLRQLPSDKLANAAQMTYMTDYNGRPPVHGQVYGYGDFYYGPSVDGEIIQGRPSVELAAGRFSKVPLLTNRETYEGDLFTNPAIITTSQSMSDLETLWQQATPHFFSRLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3K0</accession>
    <name>A0A9Q8P3K0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U2 snRNP component ist3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_00765</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756143.1">
        <property type="nucleotide sequence ID" value="XM_047899913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3K0"/>
    <dbReference type="GeneID" id="71980643"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00765"/>
    <dbReference type="OMA" id="GSWHVDY"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="33"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="189"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO11777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="37098" checksum="AF85C117FA68AD95" modified="2023-09-13" version="1">MQSIRQIERLNQTELDKCVPSNASWHTDYRDTAYVYIGGLPFELSEGDILTIFSQYGNPVHINLVRDKDTGKSKGFCFLKYEDQRSCDLAVDNLSGAGVMGRVMSVDHTRYKKKEGEVEGIMDEEEAQEDTDKEDGDRRKRRKTESESEEERPLIKEEIELQKLLRDHDDDDPMKEYLVKEKREEIAEALKSVVKHKSKDQDRGERKHRHRHHHRSRKRDDEEGGKEHRSRRRRDEHEGEPHRSRRGDKDEEDIGKHRLHRARRERSRSPGSDDCRRSERKPRKISGGSDPRRDRNGRYDSRIDGVEAVARSYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3N4</accession>
    <name>A0A9Q8P3N4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Engulfment and cell motility protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_00853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756307.1">
        <property type="nucleotide sequence ID" value="XM_047900001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3N4"/>
    <dbReference type="GeneID" id="71980731"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00853"/>
    <dbReference type="OMA" id="CPHMKDL"/>
    <dbReference type="OrthoDB" id="28413at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017124">
        <property type="term" value="F:SH3 domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="2" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0729">SH3-binding</keyword>
    <feature type="domain" description="ELMO" evidence="6">
        <location>
            <begin position="245"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO11941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="706" mass="79125" checksum="1B3DD9F68E11B11B" modified="2023-09-13" version="1">MDEPPDVATLVAGLVAESESAKKYAVYKLKGQLGDPSFADAFIQCNGLPPLRQAVLDTSGNTQAYALGSLNVLLELDMGWECIDEEVLDKALALAISHPLVNIVRNALHLLVLIVSQPLTTGISDEDAQSGFVALKPALDNHPQFLESLVHRLSASDHGLCANALQLVNALMNDAIVNGGEHEWPKFIKKLQDLGVIGGVGMLMRGDAASDADSPLATAILEFQSLTKVLLRQWRDVMVNMELPEHKRALKTINLLSKPEPYSPPPAANGVKPRKHHPEKWRRLGFETESPAWEFDETGYLGMMDLVEYCKRNEDSYVKTLMEQASLPREQRCPIARASLSVTLILYEHFEVDDAGFSSANNRNNSVSGRLMPSVDNLYKPLLLQWGRLHTAALNALMRLWKDAGAEHEDFYKMEEVVRIIVERIVGSTGRKTDVGRVEEELRRVSLETARRWQMENLNEVYQDAWGPHLVQVREQLHHESMQFMEEQRIRCLLQGSWFPTSSQASGAANWRYVRLSHNRKWLHYQNYSAKGEGEPPLADLPEQIDLNAVTSVDSNVSASEQPIMKSQNDSTETLKDSARDSAKGTTTKITILGLLSPAGSRSAEAEEGVLLELFPQTSYLASEWLDGLLMLLDQRPITKNTTRLIEMMEDWGVRLRMLNLRWEDVDWEALELSVKGDAVDSKAVPSREGVDEQYWYALPDEVEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4G3</accession>
    <name>A0A9Q8P4G3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAB6A-GEF complex partner protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_01408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757309.1">
        <property type="nucleotide sequence ID" value="XM_047900556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4G3"/>
    <dbReference type="GeneID" id="71981286"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01408"/>
    <dbReference type="OrthoDB" id="1918at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO12943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="871" mass="93029" checksum="830D7BF302EF0522" modified="2023-09-13" version="1">MPPPPPASNIRAFVHWKQPTVYAGEEIECIITFKNVAPTPGSAIENGDRLNPSAANGAVNSKRASYVPSAPHSRKSSIAQIKPPPLSRANSVASTKGAPPARGHRPALSLNVISAASRGGGLNRAPVPQYGTPNSAVRPSKGHGRSLSIMSLGCEPASERTPTAPQSAGIRPMRSHARSTSLQQPPRLVAPSPAGLIMPSPRQPSPLYEADTPPALPEGQPIPMRPGRRRPGTVSADHTPQMGRQSSFSRKLGHHSQNGSLNNFKFPATQAVDRNHLANPEQPPKLARTPSTMHSGGKRSLSPRPTEGWHAAASNLNPISRVMSETSGEGSPRTSSELYSRSNHSDETLTSEAPSGQQLGRLIPKGFHSRRPSRSPQSRPAEAETLMMAYAQTLGHFTLDGSLVNTAPFEEVKRKGVQGGGGVVGVERSKRSSGLFGALSWGNIGESLGGLLGGEEMSSMAQMKATVGSKTIPLLSTPQSLLFVDLRLAPGESQSYNYRFSLPRGLPPSHRGRAIKVVYNLSLGVQRPEGQAVKRIEIPFRVLGSYDTRGDTLGHDLMSPYVLLQDSARTTAIAKDPASTSGFPSSTTQPKPKKKRTPKQGLEDFLRYTERLMESPKDANGVLLSPTSPTSPAVLNNTSSLSRQASFADMAPANAKEAIDFAILRSNLVNRSGKQPDAQSVNRFNIARSGQPVAVLAVLRPSYRLGEPVIGVVDFTASAPSASAPTYSVLVELESSEQIDPSLALRSSHSINRVTRKVHASTRESSLFARQISFNLNIPANAAPTFETTGVSLTWRLRVEFTTQRQISGLGIEGSNVGDELLEELASDDRGTTFIARERLPADTFEIAVPLKVYGAVGIDSTSAQHEPLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4R7</accession>
    <name>A0A9Q8P4R7_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein BZZ1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CLAFUR5_00772</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BZZ1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO13007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757373.1">
        <property type="nucleotide sequence ID" value="XM_047899920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4R7"/>
    <dbReference type="GeneID" id="71980650"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00772"/>
    <dbReference type="OMA" id="YADGWWE"/>
    <dbReference type="OrthoDB" id="8783038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045010">
        <property type="term" value="P:actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000060">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000040">
        <property type="entry name" value="Actin polymerization protein Bzz1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="F-BAR" evidence="14">
        <location>
            <begin position="8"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="13">
        <location>
            <begin position="407"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="575"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="687"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="468"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="526"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="633"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="652"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UJO13007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="745" mass="81640" checksum="C2793B31C72D843E" modified="2023-09-13" version="1">MAEVDIAPQFGLELKDGFKPVNAWVANGIAWLDDIQQFYRERSVIEKEYSQKLSALAKKYHEKKAKKTSSLSVGDTPTVTPGSLESASMTTWAVQLTTLEGRAAEHDRFSSQLVSAVAEPLKHLAARYEDLRKQHAEYASKLEKERDGNYGDLKKTKDKYYGVCQEVENRRKKLDSSFDHGKQKAQSAYAQHQSDMRNAKNTYLITINVINKQKERYYHEYVPELLDSLQALSETRTSTLNNIWSTGASLETQTMTRSTQLLEHLSTEIPRNNPVLDSMMFVRHNAIQWQDPPDFVFEPSPVWLDDDTMASDPQSKTFLMNILSKSKSSLGPLQKECEAKRREVEGAKRVRQLIREGKDKRDEVEVVRAQFHNQEVLHHAERRRVTAEVEVSTITSAVGDISVGARNHTFKNQTYKIPTSCDLCGDRLWGLNAKGLSCEECGLTCHTKCELKVPADCPGELNKEQKKAIKAERQAAAQAQTAAPPPASNGHSNGNVDRTASLQRSDTIGSMNTLSSGYAASANRSVSGMTVRSSEESHATAPTTISQSTSAAGRHRVMAPPPTSYVNPNGNGSAPEEQKGKMLYAYQANGDGEISISEGQDFTVVEPDDGTGWIKIKPSSFGMPAGLVPSSYAELSAPAPPSKSPVDDRPVSMAASTSTTSLAGSDTPSVGKAKKQGPAVAPRRGAKKVKHVEAMYTYQASGPGEVDMEEGEKMVLVLADQGDGWVEVESKAGKGIVPATWVKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P501</accession>
    <name>A0A9Q8P501_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_02817</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Glycosylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the paraoxonase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757760.1">
        <property type="nucleotide sequence ID" value="XM_047901965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P501"/>
    <dbReference type="GeneID" id="71982695"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02817"/>
    <dbReference type="OMA" id="NDHYITK"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004064">
        <property type="term" value="F:arylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002640">
        <property type="entry name" value="Arylesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF30">
        <property type="entry name" value="SERUM PARAOXONASE_ARYLESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01731">
        <property type="entry name" value="Arylesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="6">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602640-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602640-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO13394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="391" mass="43335" checksum="F0E08747B27887D3" modified="2023-09-13" version="1">MGSASFVTAPVVLLLSAFLYYRSPLLYTFYYNAPDRLEKVSELGKWEIRFQDLVRNCEDIYLNDQAGWALLSCDPGRDEWNTVMGTFVNHVPPPSTGLYLYKYAEEPQTPPQKLALQRSEADQPDDFHPLGIEYHAESSTLFVANHAHSGSKVELYKLDVDEGTAVLTDTLEDAKLATPNSIAAISSDEFFVTNDHYFKVRDNLPLAKFETYAGLPFGSVAHVKLIDEEAPQITTLARLPFANGITFLNDSSVAVASSTTASIWIYSFIEARFLGGTVPSLMLSKKIPLSFVPDNISTDSNGKLLIAGHPHAPSLEKIAKNNRFCHTAAVDAEKCQLNRLSWVAEWSEETGVKNLYVGDEYGPSSTATRDVSKKIGFVTGLYERGVLVWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P537</accession>
    <name>A0A9Q8P537_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_03337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757880.1">
        <property type="nucleotide sequence ID" value="XM_047902485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P537"/>
    <dbReference type="GeneID" id="71983215"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03337"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF1">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="139"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO13514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35234" checksum="37A5FF03E592676A" modified="2023-09-13" version="1">MSESTTSDCHRSRPRPKGPQPRHALSYHTNPDYQIVALVNRSTPRCLPPELAGYNLFQTFEEALALKPDLISICTHVDTHAQYAIAAMEDGANVFVEKPLAGSLEDAQRVIEVARRTGRKLVVGYILRHHPSWREFIARARELGPPFVLRMNLNQQSRGAAWEVHKKLMEGSSPMVDCGVHYIDVMLQITDSRPVQVRGMGVRLTYFVKDVMGPRGSVSIVGEEAEAGSSADVDGHTKTSRLKIHRVEKAKDQVLSMVDEPGHQELCDLEQQFVLDAVRGDYDLSKHWADALRSQAVVLAADQSMRHKRAIDLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P547</accession>
    <name>A0A9Q8P547_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrotransposon-derived protein PEG10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_02609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P547"/>
    <dbReference type="OrthoDB" id="5088132at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032549">
        <property type="entry name" value="DUF4939"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16297">
        <property type="entry name" value="DUF4939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="386" mass="41912" checksum="1A3F3EA5F516C917" modified="2023-09-13" version="1">MGDHATDRGVNLDNQDTPFHFSEWTDIPFSNAAAFGAWANANPDTAYALINRTVSSFRETAQQVEQANNQATYLQGIVNTFQNLAPHADDNRRQHFSKKVNDPDEFDGNKSKFEAFETQLTIKLLANADHFPQEKDKVTYVFSLLRGDAAAQVQHYIDNATQTIGCPDVLTLMQDLRAAFGDPDRRATAQNAIHNLLQKNKSFAEYLAAFNRDIGFTGYNEETKKSTLRRGLSAELLRALEDKDVGAMSFRELVETCQRLDSNMKHTASLLASRSQGRQPRGPGSHFAAPLGAAAPTALPPVSVGDAMDLSAGAAVPRVQGLVNGKLTPEEKLRRRQAGLCTYCGGPGHIAANCPQLAARNARNPVRGAVGAIEPAPAAPAEQEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P5G6</accession>
    <name>A0A9Q8P5G6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Extracellular metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_03137</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758108.1">
        <property type="nucleotide sequence ID" value="XM_047902285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P5G6"/>
    <dbReference type="GeneID" id="71983015"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03137"/>
    <dbReference type="OMA" id="ECYERFT"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040161933" evidence="10">
        <location>
            <begin position="19"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="160"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO13742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="310" mass="33386" checksum="2A87E25EFD2B0356" modified="2023-09-13" version="1">MKSFTIAALAALSAVASALSGGNITSFTDPATGKTIRHFDCDVNRGKASTHFNETVKFFLRNSRRPVSGGSSASLVKRQTLSPALNVKVYMHLVTTVAKKGLLTEDNAKAQLEALNKAYTPIGLTFTLAGTTIDANDAWSVGDGTSMDDLKKARRQGTYQDLNLYFHSDLSGGVLGTCTLPSQVTKQTLPSQYFSDGCNINAETMPGREMTGYNKGMTAVHETGHWLGLLHTFEGYSCTGDGDSIADTPAQSTSTDGCPTKPPKDSCPDQTGVDSIQNYMDYSSDDCYEAFTPGQVTRIQNMWKTYRAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P640</accession>
    <name>A0A9Q8P640_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L10, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_03147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758960.1">
        <property type="nucleotide sequence ID" value="XM_047902295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P640"/>
    <dbReference type="GeneID" id="71983025"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03147"/>
    <dbReference type="OMA" id="VVTRYYT"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000011">
        <property type="entry name" value="50S ribosomal subunit protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="113"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO14594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="308" mass="34068" checksum="2ACCBCC6341F066D" modified="2023-09-13" version="1">MPPRLQLLRRAVVTIPTAQTYQPIAPFLYPFLSQQRSASILSSLSDNKGAYNKKIKRGRGPASGKGKTSGRGHKGQKQHGKVPAGFNGGQTPDWVVSGKRGFENHFSVDMTKVNLNRIQYWIDKGRLDPTQPITLKELNASRCTHGIKDGIKLLARGKEELTTPINIVVSRASAEAINAVEQLGGTVTTRYYTNFAIQKILRGEMDPVHSLQSHITKSAGSSEGAEEAAEAMEQERLQYRYRLPDPTSRKALEYYRDSAHRGYLSHMVEEGHGPSLYFKTPGMSKSSGKKASGGKQKTSAQKSENRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P6M7</accession>
    <name>A0A9Q8P6M7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047759559.1">
        <property type="nucleotide sequence ID" value="XM_047907687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P6M7"/>
    <dbReference type="GeneID" id="71988417"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08539"/>
    <dbReference type="OrthoDB" id="4502478at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO15193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="161" mass="18295" checksum="CA53897CD182DA0C" modified="2023-09-13" version="1">MTANRDALIPRLKDDPSIDPPYTFGQIDEAAMHSEVLRIYTNARKDTRIMYDLGLDRDGDHEENWIIRWLLWHVFRYRDDRNSSLGRRTGSSTRPSTDSEEPDNGSDDVSIPTDHSSAVAAATIASHQVSDAQQHAGFEEGKTSSASQARYWDPVRDRFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P702</accession>
    <name>A0A9Q8P702_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_07862</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPI-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="13">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090165">
        <property type="protein sequence ID" value="UJO15660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760026.1">
        <property type="nucleotide sequence ID" value="XM_047907010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P702"/>
    <dbReference type="GeneID" id="71987740"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07862"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="5 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="180"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="318"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="596"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="820"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="840"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO15660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="859" mass="96324" checksum="011572347BEE4FBF" modified="2023-09-13" version="1">MRLDVKRQLFARSERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTDVPVRAGRFISRKNWIVCGSDDFQLRVYNYNTSEKITSFEAHPDYIRAIVVHPTQPFVLTASDDMTIKLWDWEKGWKNVQTFEGHNHYVMGLAINPKDTNTFASACLDRTVKIWNLGSSTPNFTLEAHETKGVNHVDYYPQSDKPYLLTTSDDRTVKIWDYTTKAQIATLEGHTSNVSFACYHPELPVIISGSEDGTVKIWHANTYRLEQSLSYGLERAWCVSYQRGRQGIAMGFDDGAVVVKMGREEPAVSMDNSGKIIWARHSEILTSVIKGGDKSVKDGQAITLPSKDLGSTELYPQTLIHSPNGRFVAVCGDGEYIIYTALALRNQAFGSALDFAWASKENDKDYAIRESQYSVKIYRNFKPKSGDGTVNVGFAADGLSGGVLLGVKGQGGIGFFDWESGKLVRRIEVEPRNVYWSESGELVCLACEDTYYVLRYSREQYVAALQSGNVDEDGVEEAFEVVCDINESVRTGQWVGDCFVYTNSTNRLNYLVGDQTYTVSHFDQPYYVLGYLPRDGRVYVCDKDVQVSSFALSVSVIEYQTLVLRGDLDAAMEMLEQGEIPEDQKNKIARFLEGQGYKEQALEVATDSEHRFELALGLNELKIALELAREADVEHKWKTVGDAALTGWDVKLAEECFRNANDLGSLLLIYTSSCNHESLRMLAEKAQTAGQHNVAFTCYHQLGDKDACLDILLQTNRHAEATLFAQTYKPSRAQDIATAWKGSLEKSGKGKVARLLGVPGEDEEMFPEWEEYLRLEREGGAHGDLIDINGDADPVEKAAPVEADGEEEEEAEEASSQTETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7Z1</accession>
    <name>A0A9Q8P7Z1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U5 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_04568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761016.1">
        <property type="nucleotide sequence ID" value="XM_047903716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7Z1"/>
    <dbReference type="GeneID" id="71984446"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04568"/>
    <dbReference type="OMA" id="IWDIRPY"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="99"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="275"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="317"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO16650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="352" mass="37444" checksum="F8C9DAF11EC0BA74" modified="2023-09-13" version="1">MSGDKRPASATFGSSQLVKRQRNDGDANAGALQKANGSALVQGGTAANLPASVMELSGHTGEVFCARFDPSGAHIASGSMDKNILLWNTTGEVDNYVILTGHKSAVLDLHWSRDSQVVYSASADKTVASFNVETGERIRKHVGHDEIINCLDVSKRGEEFLVSGSDDGYVCVWDPRAKAAIDDIQTSFPVTAIALAEAGNELFTGSIDNEIKVWDLRMKKVQYTLAGHTDTITSLAVSPDTQSLLSNSHDSTVRVWDIRPFAPAERAVKTYDGAHAGLEKNLFRACWGPGGKLIAAGGGDGTATVWDSKSAKLISKLPGHKGAVNDVRISPDGSMVLSASTDRNMLLGHIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P7Z7</accession>
    <name>A0A9Q8P7Z7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760909.1">
        <property type="nucleotide sequence ID" value="XM_047904096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P7Z7"/>
    <dbReference type="GeneID" id="71984826"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04948"/>
    <dbReference type="OMA" id="VNEEEYM"/>
    <dbReference type="OrthoDB" id="3647549at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="683" mass="75809" checksum="402096B203D378D5" modified="2023-09-13" version="1">MSNSYYGQGEQDQWSHYQSNSKYRTDTQQRQQQERARQRAAYEARAAPQSQATDANIDMASRNFNYMNLDGYGRPGPSNTINRTEDGRFVKENVSSRDQHRRGASDNTTDTREDTRPTSSASTKSSIFGGFSFSRNGTGASSSSHKHSSSAGDERQRRPSIKEKVQDVYRRMSNSYNKATDNFSKAVDPYVNITKLNAHERQRWEAELRQGAEDKEEEKRRSQSSYHQSYQQAYPSSPTTSHVPSRYSGESRTETFDFIERSETNQSTAPKPKKSKDLLTTGERAAVFVSKIVDPVKKRRDSDDSDMSFADIAPPAELDTCSRCGEAVTGFLTKGRCAECHKNWLQEFWDASDSPAISAQALDPEGTNSDYSNRSSSSSSPGIPRDVNEEEYMKLTASHRIRRVRQTMYSDPGNPFSLDDYSPTDAVAKELGNAVYDPDAIPTILKRLSDAVAEPEAESPISLGPNPFEEQAANHKTILEPEFIMLTPSSADITTIKLESTVYNPASPTTALAAPEQEPDSPISLGPNPFEERPSLNASPVLTRDSAQLLAPTPKRSGTPTLIRDHSIPSPTPPPKDENSRMILSGSVRRTVHPLRHRRSETVPSGSERKIGAGIGAGAGIRDTKFYGFYDDVLDGLQPNGSLGPRPSTALARHRSSSLRYLMATDLFIDGDLIMLYQRRRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8W6</accession>
    <name>A0A9Q8P8W6_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">V-type proton ATPase subunit c'</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Vacuolar proton pump c' subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_05745</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761798.1">
        <property type="nucleotide sequence ID" value="XM_047904893.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71985623"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05745"/>
    <dbReference type="OrthoDB" id="5418235at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
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            <begin position="12"/>
            <end position="35"/>
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    <sequence length="1386" mass="151893" checksum="3B1BC2DFA6BED4CC" modified="2023-09-13" version="1">MASAEYTPKFAPFLGMAGIAFAMIFGCMGAAYGTAKSGIGIANVGTFRPDLIMKSLIPVVMSGIIAVYALVVAVLIAGNMKPPPEMEYSLFNGCMHLACGLSVGLTGLAAGYAIGVVGDSGVRAYMQQSRIFVGMVLILIFGEVLGLYGAQHAPMHRKFRIQKDRLVTWGLEWSDQEKGLDADIDEEVAKAGLTETVTSVMHNIQEVLIESESIRSASLPLRKAGELITADPAPFDEARYEDLLKDLTTSIDTLYDLSMSRRAIARGEHPKFEDPMTEEAAAAVEASSGSSKQKRIPRKALHEKSLYEPSFASSATTLINPPPFERPVLSPYAGLPARIEASALRLPNEGPPPYEAIGVPSTTRMIALLARNRAPESVQQATGSPAPEVPVLIEYASYDTTYRETGVPPPLQRLEALAQFLQPMRAESQTNLSLLGYFENLHQPRIGLVYDLPYSILNKVPAHRASEALMPLSLLKLVQKSNRTQSQAPEVPPPALEHRFRMALRLTEQLHSLHARQIAHGNINSSSIIFTTAKTDSDAARLDHLRAPLWASFDVFSKCTVEGIRREPAFNIYRHPHDEPNKDSRGFPVDLKFDLYGLGLVLLEVGLWTPISELYKSKYTIPDFKLRLEKLWIPKLGAKCGSAYQRAVETCLRLSDDPDNSRLTVEGIYGILLQFLKRCCLLDDVGSSTELIPVSELMSAPNSPAMTMSSAPSRRQRRRISEASSLARAQTEPSEHVPSPKNPPQRHYTAPVPSPAAIARLSSAGVASYNEPPISRQSSRASQLSPRPSFNEVRNQLVDAGNQIKEDVQFTASSTSFKDFKRRVTLIQQKWRECQAFKEKKRTQQYVQHLEQRRSIEGLREKRSRPKRYEFSTVPVPPEAWDYFQEHIVSQVMNLMQKTLPIKESSSINLVSYGETPDTTKPTVIVTCEKHASMAKAKHILKRHLKIDKNILDIRVKQDIVRRCRRSRRDRASNASRSMAPWRDPDVVKAANGEYQQQPVCGASIGSYRYDEHLPPASFGGLVVVDGTTYGMSVHHMLEPEEAIEDEQEEDAEEGADDESETSSLGGSDDGDLSDEDNLSTVRPASTIDDEPMALNDTDGDCPGITPDDMEEITITQPALDDAIDCDLHAEEDEDDDDSGIDEDHLLSFKLGLVHASSGLRRTAKSHEGGFKSVSQSLPQEIDWALFELLPPRTHPFNLITGGQKFCSASPDRKGNTLPQTFQPSTNLSCKTVYCLGRTSGLGHGTVSANMVPVKIHGRSTYSASWTVAGTFGTGGDSGAWVVDSEDGKVCGHVLASRTGQTYICPMDLLLEDIKQTLGAREVVLPAVTEVGGSSRPSSSSSSSERKAMLADAINRMRIGEAEAAGGVAIPPSSSPVRAREVEPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P910</accession>
    <name>A0A9Q8P910_PASFU</name>
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        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">CLAFUR5_06441</name>
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    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
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        <property type="nucleotide sequence ID" value="XM_047905589.1"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
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        <property type="entry name" value="von Willebrand factor, type A domain"/>
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        <property type="entry name" value="CLCR"/>
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        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
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        <property type="entry name" value="PH domain-like"/>
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        <property type="entry name" value="vWA-like"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ZF_RING_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
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        <location>
            <begin position="325"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="514"/>
            <end position="687"/>
        </location>
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            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
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            <begin position="888"/>
            <end position="945"/>
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        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
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            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
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        <location>
            <begin position="475"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="894"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="931"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO17774.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1035" mass="114677" checksum="EBF6F1FA18C4C52B" modified="2023-09-13" version="1">MYAAKGNSRKERSFIGNSCAACDEPVEHMLRGERVQSLSCGHVAHEACLYEYISEFKAKDCPTCGQVLGLDTTRGGNLDFEKFNKIVRDAPVASLRERWEPTSTPLPWEPEPVRRPSTIEHHQPVPQRPAKHHLIPAQQQGTEHDWDEHLLPAKPQSIENYEAKHNGSHGSQTSHGRTVSGETNMPARNDYSDVYSVVGRRHDYDVQSMEASVKSPRHLSRYPIPAPTVTVRSEFPTLSKSRHQQSLTCLVTVEVVEGSWQPQSEDLRSPPAVPSPIPGERFETPTPQPTLSFAPRAVDSVHEDLALIAKKEELFKRVVDWHGLDFERFGKLILHGIVRVGKNRQSWQELECYLFSEMLICVKEKKVPSTTSQHREDPRPQPRCTLKGSILIRRHLKAVELDRDEDILTLILSVAELPAFHLHFNDSQELETWRRTLNSINRPEPPTPVRPDFDHDASGTDEEDYVSRQKRRISSLPSSSYGATRSQATAPTEYSGNGVQDIRLGTSSLHVPLDIVVVVPVSASMHGLKINLLRDALRFLVSGLGERDRMGLVTFGSGGGGVPLVGMATKSWQGWSGALESIQPIHHKTMRADVVEGASVAMDLLMQRRSSNPLSHILLISDSAASETESVEFVVQRAEAAKVGIHSFGLGLTHKPDAMVELSTKTKASYTYVKDWMMLRECLAGCIGALQSVSHQNAKLRLRLPEGSPAKFVKISGAFQITKRATGRDAEASLGDLRFGDKRDVLVQLAIQPENSTPDSIPSDPWESMISGLEALGPIDQEDQRTLSVEELPLLQADLVWSDVVRDCQLSQLPRPSLLAITMLPSSKKTAYGRPVTPPIPPHPSIVQRRMELLTSDMLSRALSLVSRGQHERAHHLLSETRSILKGLAKGGLPPLPSPAPTTASPPTPRAPEHQMSALDTTFPPPPPSSRSPISPYESEPTSPFVPAAGIDRSTMLALDMELESSLEWICHPAVFSRDARKAVLQAIGVVSSQRGYTFRTASEALWAGRIPGVRRLTDRSREWRQAGDERIMYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P953</accession>
    <name>A0A9Q8P953_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_05861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO17687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762053.1">
        <property type="nucleotide sequence ID" value="XM_047905009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P953"/>
    <dbReference type="GeneID" id="71985739"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05861"/>
    <dbReference type="OrthoDB" id="4502478at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO17687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="188" mass="21896" checksum="AB2EFCD814470ECC" modified="2023-09-13" version="1">MSQALASLPRSESKARFMVRIGLDIRDPRHRQIYNLMKDEASDGRSRIMLLLGIEERSQHHDSGHRRLSGAEIPAITTSGVPEQVMNNEINQIYLRAGPATKILYQLALDPDHPNDPNWIIRWMLWHVFRYRDGRQSRLDTALLNGTRELPSSEDEGVADQVDPRLAAIQRSLYDEWRYDPVRDRWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9F4</accession>
    <name>A0A9Q8P9F4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_06491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090167">
        <property type="protein sequence ID" value="UJO18103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762469.1">
        <property type="nucleotide sequence ID" value="XM_047905639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9F4"/>
    <dbReference type="GeneID" id="71986369"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06491"/>
    <dbReference type="OrthoDB" id="4161589at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO18103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="61412" checksum="2B4B8E988409E031" modified="2023-09-13" version="1">MTLAASDVDMSVGPSKPAMQAPPATATTTSHTASSAPPYPPAGYSPLNLSSPDEPRTAAAAIATANAALSQHHTPTPNNASLGKKRKASGQPGSRGVANLTPDQLAKKRANDREAQRAIRERTRNTIEALERRIRELESQHPYQELQRVAQERDRALADCEELRKRLGSIAGIVGGSQRPDLNELAALTAQQPPLPTNQQNSQNQQAYSTSPQGPTFEQQQHIHPELRSPESSHIQTSPPSRTASTGPAFQAGESTLRRWSPSLNHPPGPHFATTNGVQHDQRPPSSSHVQQHTPNGDRHGLSFLLEPSNSTSSATQSCHSPATPEQPIYARLTNVGRASCPLDYLLIDFHRSRTRMLSEGMSKFDAIGPDYPTFAALIDPNSPEREHQHPVSALLVDMLSKFPDVAELPEKVAVLYVMFLVLRWLICPCADCYERLPTMCRPIQEQYDRTHACWLDYLPWPHMRKTLCTGEREVHFDDWFVPYTKTISLNWHMGDEYVLVPAGDNERPSLKLSPAFETHLRNLSNWNLGSEFQRQYPEFVDETVRIKDNGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9M2</accession>
    <name>A0A9Q8P9M2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762801.1">
        <property type="nucleotide sequence ID" value="XM_047906005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9M2"/>
    <dbReference type="GeneID" id="71986735"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06857"/>
    <dbReference type="OrthoDB" id="5272229at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="541" mass="58724" checksum="C4E0AEDA28E48509" modified="2023-09-13" version="1">MSVYLNALDPSSAPRVTAFASTGATKFFLPLLVWHRSLWTDIPAMWSKAKADAVAACTANEATSASIKTLVTTVDGFSSSVKDLTKAIEGLTAQTALAVGEMKSTNAFISNTVDAVHTIQQDNKEIAQLTLLSSNTVSLLRRQVHAIMEEHLRVHVTLHSQYQVFDASGGLPFSFVFGLCQHSSADSDPMPLTLNTRNSVFDVPWALANGLLELCERNDQGGEDILDLSDLDTSDAGEGETVTLPSPLSRTDNWRNSFTTFLHKIKPGSDLASRLQNGRPYTMRLRSQDWASNLPSQDLSPAKLINQKLSAGKATFTSAPALTWPPIIETRLRRQLSDDNDHVLLEISALNTSEEPVTVQTHGPQRFLTPSDPFFRPGQDDISDHRARLIDVASERAAPSAVQVIDLASGSVVRDIPRPTSASLTQGHDKRPKQESLVTLMPGEPVVKNINVANLLNGLSDGKYGIRLVPRGTWWCTGTMEDAIEEEGDRVVEEKFRADIPPLMLQSEDIVEVTVRDGKGAGQASLDIVAPGAANDDDGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9V3</accession>
    <name>A0A9Q8P9V3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_07296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762923.1">
        <property type="nucleotide sequence ID" value="XM_047906444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9V3"/>
    <dbReference type="GeneID" id="71987174"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07296"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="141" mass="15821" checksum="38AD680434A1CB38" modified="2023-09-13" version="1">MDARKLAAAAFLKPELETSDYYDMRKDVICAHIKKHVDARTPVSSFNELYAAVSASIEKETGFAVPPNGVEKAYNKWRVESGVDERTYVTSRQNFQTEGMQQALDEAGKQKAPSTFTGHKAQRAMSQYLQKKSKAMIMLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P9W9</accession>
    <name>A0A9Q8P9W9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047762936.1">
        <property type="nucleotide sequence ID" value="XM_047906655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P9W9"/>
    <dbReference type="GeneID" id="71987385"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07507"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="223"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO18570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="379" mass="41338" checksum="E88D30A6045060C8" modified="2023-09-13" version="1">MPLIRGRDASLRRNSRKIGRYIPVSTTFPSTKRARASPYITTIMPPQTNGTPPTVKKVGYIGLGNAGFSMASNLPKAGYNVVVHDADDAKVQKAASEWSNTTAANGKPEAFADCEIIVTMLPQGKIVREVLLGKDNFARALKPGTIIIDTSSSSPFDTIALGKELAEHQLKLIDSPITQTYMHATDNGESTLMVGADDEQDFKKAEPIIGTMAGYVFHMGKLGNGHATKTLNNYIMASSICALADSLVTGQKYGLDPQQMIDVLNVGTGVCFPTLDTFRRDGLTGRYNSGFGLALLVKDLSITEEFMQHNGFQTDLPALTRRYLGDAFKEVEPMADHTEALVGWEKRSGVQLKKTEKAEDIPQKDFDHRLQGLNRPSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PA31</accession>
    <name>A0A9Q8PA31_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PSI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_07550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763044.1">
        <property type="nucleotide sequence ID" value="XM_047906698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PA31"/>
    <dbReference type="GeneID" id="71987428"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07550"/>
    <dbReference type="OMA" id="CPLRSER"/>
    <dbReference type="OrthoDB" id="5427091at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO18678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18969" checksum="7B56C77DDF9BBE78" modified="2023-09-13" version="1">MDYDGAVKMGRAAACWRIQDCGSCLHSKHGCGWCPVSSTCVPSTNLLDPISKADICPLRSERFELRTKALGCNCSTTTLLSVIVTVFVTIAALGLVYAIFAAIRDVHPFLGTGNFEGTELEIKEDGTRVEKSWWRDSWRKWIYRVFARPDLNHGSEQEVRTERARLLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAH0</accession>
    <name>A0A9Q8PAH0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO18874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763240.1">
        <property type="nucleotide sequence ID" value="XM_047905897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAH0"/>
    <dbReference type="GeneID" id="71986627"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06749"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO18874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="80" mass="8970" checksum="63DCFA033CBB40A8" modified="2023-09-13" version="1">MRKDGSLQKDRETVKTIITYLAEYREHKRAKQHESDLQTANAVLGFCCSAIWPGGHSTKRMAATSQGVLIGIMEKYEPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAT0</accession>
    <name>A0A9Q8PAT0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_06889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763434.1">
        <property type="nucleotide sequence ID" value="XM_047906037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAT0"/>
    <dbReference type="GeneID" id="71986767"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06889"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="225" mass="26053" checksum="4AF9409596398F0A" modified="2023-09-13" version="1">MATFRALTMKYVWRTARRHIDREYSVLTMALSEVDIPEPSQWNTHFAAASNCLADGSPTNVTIHLYGPLISDEDWIRVDESDFARPFDPTHHSKVVKPVVDNWIKVIRETKIQPSHYKTQSQEDSPEQSDNTLRFTLDVTQPLDIDNSTRHLLLQHEARSTVRIAALLNKIFRPVGRQLEVSVKGARCWCTLREKERHVVMPKGLSYPVDRASHMQEQMEYMRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBE3</accession>
    <name>A0A9Q8PBE3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_07383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">Race5_Kim</strain>
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    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
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            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
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    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
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        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
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        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
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        <location>
            <begin position="330"/>
            <end position="352"/>
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    </feature>
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        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="166"/>
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        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO19322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="41138" checksum="599BBE737D23D819" modified="2023-09-13" version="1">MAGLVTNASGLIALRFFVGILGGTFVPCQVWSTGFFDKNVVGSSNALIGGWGNAGGGITYFLMPLIYDSLKSDQGLSSHVAWRVAFIVPFILIVSTALGMLLLCDDTPTGKWSERHDNAQRLAHSAQAAVVSSPGHASSGSSTPEVREKRDMEKGEGDASDYQQPKQGEMTDLAVGEVIVAPTLKHTLHIITSPQTLFHCATYFCSFGGELAINSYLGAYYLRNFPYLGQTQAGRWASMFGLPNVVTRPLGGIIADILFKHTKSLWVKKCWILFVGIVSGAFLIAIGLTDPSSESMMFGLIAGMAIFVEAGNGANFALVPHVHPSANGVLSGTVGAVGNLGGVIFAIVFRYHHADYATSFWITGVMTIGMNLILCWVKPLPKGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBM4</accession>
    <name>A0A9Q8PBM4_PASFU</name>
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        <submittedName>
            <fullName evidence="13">Cardiolipin synthase (CMP-forming)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_07173</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71987051"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07173"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidyl synthase"/>
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    </dbReference>
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        <property type="entry name" value="CDP-alcohol_PTase-I"/>
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        <property type="entry name" value="CDP-OH_P_trans"/>
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        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
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    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
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    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
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            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="386"/>
        </location>
    </feature>
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        <location>
            <begin position="64"/>
            <end position="134"/>
        </location>
    </feature>
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        <location>
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            <end position="100"/>
        </location>
    </feature>
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        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO19504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="409" mass="44721" checksum="ED33E3C0BC4B6AD3" modified="2023-09-13" version="1">MLFQRLHVQHRQHVMRTASSTSALTARFQCAATTVRSPPQGRAAIHGATRHVCPLRSLAQGPSSFLRSSNAALRTPPPKRLLSERSRDKRHPPVQEHHVDQSSSQPQPSRDRPVTRSLEAARERTKAVRNKVRSSLTSLTPHENIYNLPNFLTVTRLFAAPATAYLLLHDHHTWALALFAYAGITDLVDGWLARKWKLQTVAGSVMDPMADKALMIILTATLAVKGAIPLYLATLILGRDASLAVAALYYRLASLPAPKTFARYWDFSLPSAEVHPTTVSKYNTFLQLILIGSTLALPVVTASGEQIAILQSFGLTTGKLHAAMTYFQYVVAATTTWSGLSYAYLKNAVTILGTNEEVKARQGARGRAIIGLTFGSCVLATAWLALNVDKPSIEGRNTLDEDAGGNSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBN7</accession>
    <name>A0A9Q8PBN7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-splicing factor cwf14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBN7"/>
    <dbReference type="GeneID" id="71987048"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07170"/>
    <dbReference type="OrthoDB" id="277109at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00997">
        <property type="entry name" value="G10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="163" mass="18968" checksum="1019191CAEE6B346" modified="2023-09-13" version="1">MPAIRTSKNRKPPPDGFDDLEDTLLEFSNKMKDAENASHEGKKKHEMQWPIFQITHQLGRRKDYIQALQGPKGSRYIYDLYYEKEAISRQLYDWLLKNGYADANLIAKWKKQGYEKLCCLRCIQTKETNFNSTCICRVPREQLKEDQEIQCVSCGCMGCASSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC04</accession>
    <name>A0A9Q8PC04_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ASST-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763988.1">
        <property type="nucleotide sequence ID" value="XM_047909656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC04"/>
    <dbReference type="GeneID" id="71990386"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10508"/>
    <dbReference type="OMA" id="CWINDCL"/>
    <dbReference type="OrthoDB" id="5427350at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="72065" checksum="DAC672D39C86A02D" modified="2023-09-13" version="1">MPWAHGLQHLRTALRCILIAAALLTFLFVFHQCILPIVAFIIPSLDSTFFDWGVYGLYPIQQYNSFNLSGPQAKHVRWNDKCDQGHILLTPNGPSVARPGPMILDSKGGLVWTSDDFGATANLKVQHYNGEDYLTLWSGEKAATSGKGLYFMLDSTYQVVRMVTAVGDELFGDLHEFKITPQGTGLLTVYTTTNADLRGMGHGRGLEGWIVDNLFQEINIETGELLCQWRASDHFDPVETYMTNPFGGYWESIPFDFYHLNSVDKDSQGNYIISSRHFHHVVCVSPAGETLWILGGRDNQFKDLSDGKATDFRWQHDARWFSEKDGIITLFDNQKAGPLHKDASHSRALFIQLDIPNKTAKLVHELSSLQGILASSQGSVQTLPENDQQIFVGWGSAAAYSEYTAEGDLMCETHLGASWFYWFERMKSYRTTKALNWHGTPSTPPQLKIDDDALYVSWNGATEVASWSLEVSFDDHAVATEDLRRVDGTPAKVSEESFESIDIIPRVGFEGTFDLPSLSSAEEQSARYRVAALDKDHQVLRYSDIVSHADVVSESSYIWILFKLCLVIGILFGIRIAFKWFRSGQSIRSYANTQRGYSAMPAWMDMAPSTTWKRANFRSRPKLYDWAQFRWRAATSRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PC78</accession>
    <name>A0A9Q8PC78_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peroxisomal membrane protein PEX30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09867</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764155.1">
        <property type="nucleotide sequence ID" value="XM_047909015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PC78"/>
    <dbReference type="GeneID" id="71989745"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09867"/>
    <dbReference type="OrthoDB" id="5586090at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00694">
        <property type="entry name" value="DysFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxin/Ferlin" evidence="7">
        <location>
            <begin position="317"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxin/Ferlin" evidence="8">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO19789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="548" mass="61480" checksum="7B91A5A45284AB67" modified="2023-09-13" version="1">MAAFDTPWTTSMSDRPSNSHAYDGARDNSVPETTVAPFSPNQQTVTKNRNKATVLIHQKSPLLAATPPQVTRALAYSHPFIVPLNYLVGLLSWTTGDPWESFLMVAVFWFTILYVDDLLRWAGPIVVVAALIAGMYSRRYSPLSSTTWSGHKRKRSRAASESEYRKSLDEILDTLQIFTNRCDVLLDPLLRLTEFLSTQTTATSATTRPALTSMLIRLLAITPTWIILMLPPFRIITMQRILLVLGTIGLTWHSMPARASRSILWRSKAARTAASFITGLNYGTPSTAKDKRTPPFLPPRAPAALVNALKRKGTSAGVRFTFALYENQRRWVLLGYTANLLPNERQAWSDEHQNTVSGKENFPLPETDSETTKWRWVPDSNWRVDPAWTEDPSGKASRDKEGWTYYDNKWQGGSRIDDWNKWTRRRRWIRDAELVEISPEEAAAEAANTTTDADSESIAPSMVTTDFADGDSISTAVKKKGWFGRRKLTNEKIRAIDKVEIASMSGSGETGGTRASRDSPEDDVYTPLQYRGNEYDRSIGDGLTEMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDE3</accession>
    <name>A0A9Q8PDE3_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_10054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764751.1">
        <property type="nucleotide sequence ID" value="XM_047909202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDE3"/>
    <dbReference type="GeneID" id="71989932"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10054"/>
    <dbReference type="OrthoDB" id="3644903at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055499">
        <property type="entry name" value="DUF7071"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23257">
        <property type="entry name" value="DUF7071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="792"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="254"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="347"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="626"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="692"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="871"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="910"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1147" mass="126150" checksum="E8CB7122F5324B25" modified="2023-09-13" version="1">MTMLRWDRNLLGLERSLGLRSERGISRQSNKDAPPIEQLLDSIKLIARRWVSATNREIRTSEVLKQDALGLFDEYGPTIWPDDEVRPSWLEDPSEDAYEGRYPKDLYYSDLDDREVLSSYFCDLVVEKCIKYHDNQLQKHRRLSKVHSATPTKQDVDSEDDNDDSALLDRLEASVEAAGDHEEVETYAADSRPTWAPVNKQPEVHRTPEVRKTPEEALAVVPAMPAPASPVSGMTAAKSEPSYGDFSRYYVTEAESPEPEVQTQPRLRASAQTDKLRATEERRDSAIAAKDANRAGSAPAHSGSPSRKRPRAIDPDEPVFRVKRKRGGAKWSWMFTFKVDPEKLRRILAGERVAPPIVNEESDDWTEDEDEPSRASTDIDWHDKDETNAESKPDPEDEAEQRPEADPEADTARVGSSRSRSVASWDNSSVSDHGRDAGEREFSPSEPGDSATPIAEHAAASQDKDANAGAEVSEDIEMTDANIDDHKDEDMPIVDAPAPDSLPRGDGANERKQSTGSTLPGIAPVHDVKRSKDRQTEVNNLRGIVADALFSDPVGKGVNIPQFSSFIADMLESSLYVLCLRSSAPYEVKLAQLKSTLRVGGRMMQDLMRGQCRPQDVVGMVMALQPPRKESSTNEPISLDTPPKDSNGVASANGSAKSPVPVKNLAGLAEAQRRASDAAAGTTTFISQSPAMAASKLKQPTMSPNATPVRRPSSHSKPASKPPSVVKPLVTQPRHDQVVGFRASVASPTARAFEETRIDDIAPLPGNPANFRPLSAAPTQGKFQIAPPNTHRCVCQKQPSPYDNGQLIQCGNCKVMQHKICMGVPTVLPRGHLYCCEQCRPDAHVETVKALQQGHRIWEIRANNFALSQQAQQKRVSNSPQVQAPPPARILSSSVVPGHAHPEPRPPTLPSQSPSVQPQVVSFGNSLPSQHLKQVNKPRVTPTPPYQTEIMSQELGRRIMGDMMQMPVVQLILQAGSSWTEDQLLDLKAALTEAPGGGNDLSVLAKHLFKSRHAFKQDITSMKQESTGAGDPDALELDVEVNWNRNLDFNDSIPMPDATTAEDFFLQLEAELPDEIRDEQKTIKEVRVKSLTELKCGPFSRIVRGKAGDAGLRSARKKLKSLGKDVEPELQFFVVWQDKVRTASVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDT1</accession>
    <name>A0A9Q8PDT1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_10818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764948.1">
        <property type="nucleotide sequence ID" value="XM_047909966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDT1"/>
    <dbReference type="GeneID" id="71990696"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10818"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="212" mass="24096" checksum="237B672320678465" modified="2023-09-13" version="1">MPPTLALTSVAKPLTPRDKSPLSKLSPEMRNMIYALVFDGSPTFVQEWDPKYRARTKGQGLDFKNPDNFIHWAKKIGPQRRNLLTDVVLAPMPRCISQAPFIFDPAEALRTFAQDAKLLLDRVVHKGGVSSGVVKISFPIWYGHAEKWWTSDPVRFVEGILLDRRDQHDHITSLRILNAIHSVYNDPFGRTLELSMRPPRLLCKHDGYGILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PE60</accession>
    <name>A0A9Q8PE60_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase asqE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765160.1">
        <property type="nucleotide sequence ID" value="XM_047910062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PE60"/>
    <dbReference type="GeneID" id="71990792"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10914"/>
    <dbReference type="OMA" id="ARPYQDF"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="268" mass="27740" checksum="6B70DAD88D88E584" modified="2023-09-13" version="1">METIAAPLRGKCALVTGGSRGIGAAIAIKLAEQGCSKIAITYSSNQIKAEEVLAAIAQICPEIKTCTFSANLADPNFGEVVIERTLSGLKTDKIDIVISNAASVDIGQMSPAASMPKPEWDAMMTQNAWSPLALARAAVTKMPPGGRIIMLSSGSSKVAFGDPTVAYAASKAAMDSVAKNLAAIWGVQYGVTVNSVSVGATATDAFKKGLEQWGEEFAKWSGELSLLERHGEAREVAAIVAFIASPEASWIVGNQIPANGGSLSVLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEC0</accession>
    <name>A0A9Q8PEC0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux pump himE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_11008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765236.1">
        <property type="nucleotide sequence ID" value="XM_047910156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEC0"/>
    <dbReference type="GeneID" id="71990886"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11008"/>
    <dbReference type="OMA" id="QEVEFMI"/>
    <dbReference type="OrthoDB" id="4521223at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO20870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="33249" checksum="46BFEF4973EFBE78" modified="2023-09-13" version="1">MASNITVDPFENCTSVTPLCPVEATTYGYTPNLAANVILLVVFGLTASAQLGLAIKTRLPAFGTVVTAGCVAEAIGYIGRIIMHNNPWNENGFMIQIVCIILAPSFLAAGIYLTLKHIILTLGPSKSRLPPYLYTWIFISADALSIILQAAGGGIAAGSDNDPDLQDIGNNLMIAGVAVQVATMAICFLLAIDFGVALVRSKSISRKGYGGGEGLGGGHEEYSRTGRFRVYLVCTCLAFTTIFIRCIYRLPEMAGGWGGSLMRKETDFMILDGAMIAIACILLTVAHPGIFFPDMRIRPSKLQSPSMEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEV6</accession>
    <name>A0A9Q8PEV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent monooxygenase atnJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CLAFUR5_11095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO21178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047910243.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71990973"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11095"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
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        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF261">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="42"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="281"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="UJO21178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="672" mass="72652" checksum="E6D05FF3CFC4AC56" modified="2023-09-13" version="1">MKNTHAADSGANGTNPSNGSLGPHDNGVTTGLQGLGKEQPLTILIVGAGIGGLTAGIALRQAGHIVKIFESSGFASETGAAIHLPPNTNGIMRRLGIIAQDFGSNPMCMMKESDGQGNVIRGMDMRKMNKIWQHAWLLAHRIHLHDALKRMAISEAGEGRPCELHTRSRVQNVDEVNGVITFEHGGTATGGVVIGADGVHSIARNSIDPDTKPFGSGKSAFRFLIPKETIKNDPITSHLVDEDGELKIWYEDDRRIVMYPTSNNTILNFVCIHPSSESDASRLALIGDAAHPFLPHQGQGAGAAIEDAASIAVVLPLGTTPSQVPARLSLYDTIRHERATKIQTISRIIGGDNLQKKKELDMFGFTNYNFGHDEFDHSAQKFREYQWSLVEKKYSRMPLAFGPMPGPRQDHYGNPRSGAYSTFTTASIQFKTSATLLRTLLPPGREGYKFSAPGTVAYASFSCTTLNNMAWLGGGGYNHIGLYIHGVEYTSPSSGETYKGAYMPILFENLVDPIVSGREELGMPKLYSSIDIARRSGSYHIRTGWQGVNWGTLSLTGLTEATTATPTSMTGSNDEGILVHRYIPAVGKEMKGEAEADYAVFDKFSDAVPQAKVTRTLIAKDAKFSIDGMSWDELPTLHHVIERLAELPVYEIVGAKVAEGTGVSDVSSAKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PEX2</accession>
    <name>A0A9Q8PEX2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_11099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765536.1">
        <property type="nucleotide sequence ID" value="XM_047910247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PEX2"/>
    <dbReference type="GeneID" id="71990977"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11099"/>
    <dbReference type="OMA" id="QHVENYY"/>
    <dbReference type="OrthoDB" id="3650890at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="506" mass="54118" checksum="E66842DC182B63C8" modified="2023-09-13" version="1">MAQVTIYYLATWTYNGVAQGRVASNAVTRGLATGGQFADINTEDGDLVLTAEDANASPTTFRTAVPLFVTNATDSTTSVGVVTECTEFTINARENEAAPSSCDARSEASIVSSASTTLTSTDATSSALSSNGASAETTTISNVPTNSNATSPTTASRSPSPTTTQTSGITNAEAAGVGIGSAVLGALLAAAIVFCLMRRRRKHTAPRGTPSNTARGVPSAAPTDGSSLGKYDNKGDAVSALSPCAADMDLPPPEEDRAIAGSISRLETMIKNHAQSFYAGSQDFGVPLAGDPLSNHLQQLLGNRAPIKAEAMMTLLAKSRSRVGAVRFLLAWTILESVDVHALPEHSLLPPELIGFVRTSQSIVKDQPALYSRWRFYSGLLLRHFYGSKTLPAADVRQQIISKTVARLDLVLRSFATMRTTSNAEQTREQNMEEIVRLGAQSGYTLFIQPTTWKLEWTDRRVHSDNELVVFPALFKIGDEQGRMYTPDMYHAFGHSQTMDVGRVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF17</accession>
    <name>A0A9Q8PF17_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Necrosis-inducing secreted protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_11170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765598.1">
        <property type="nucleotide sequence ID" value="XM_047910318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF17"/>
    <dbReference type="GeneID" id="71991048"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11170"/>
    <dbReference type="OrthoDB" id="3913322at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="131" mass="14260" checksum="B6000DD5EF8113EF" modified="2023-09-13" version="1">MTLGKRNTPILRCVVVLCESEANARGDEAKWGMRRSGWRISPSNTLYLGALGTYLDTKFLGPDFSNEIGNITHYVHIPATTAKGEYTIQGAHFELTGVSTGPATSVYYANITVGDNTSSEYVRSALIPQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFG2</accession>
    <name>A0A9Q8PFG2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_09268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765874.1">
        <property type="nucleotide sequence ID" value="XM_047908416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFG2"/>
    <dbReference type="GeneID" id="71989146"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09268"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="56"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="360"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO21508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="571" mass="64184" checksum="5BCCCF5C3A312BF1" modified="2023-09-13" version="1">MEESTATLSAPAPSQPHTRSSSRAPSAPRREETSDSEKAGRVWARGVDDPWHPCILTLDGGGIRGYSSLMILKALMHEVWIWEQYYDRETVTVRTDSPTELHSSFEQDEEQAEAGALRGRSGHHRTLGNDPDQGHEQHGIETELGQIATAPAAARETLLQDALTADLSTRKAASEAELLPCHYFDFMYGTSTGGLIATILGRLRMTVTEGLELYRKVGDDLFGKRRSKIPLMTKYYHEPFEKAVRDIVSSRCHEHPNCDGNDLHPWDSSNPIQEPFDVDKPRVCQQCCLSATHDENISEAYLLRSYAHYYSEDAPNWITRYNEGADPIPIWTVTRATTAAPFYFEMVEAIVADQQKSFKDGGIRENNPSGAALSEFHSLYEGKAADPALMLSVGTGRPNTKNDGFRSSAPWSIPFVNKFLEKRAVIQNLLIKYTEGEKQHKNMREYAHGEHTWYKRLNVSKGFEDMPLDEWQRGIWTDPNTGEERTVAGGASLTKMEEATEEYLNRPFDPEIDSYAPPMTMLKQAAQKLVLQRRAREELGGERWDVFVGKNLHGRKVNAEVDADGRNGHVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFS5</accession>
    <name>A0A9Q8PFS5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765973.1">
        <property type="nucleotide sequence ID" value="XM_047908377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PFS5"/>
    <dbReference type="GeneID" id="71989107"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09229"/>
    <dbReference type="OMA" id="RDKGTEC"/>
    <dbReference type="OrthoDB" id="5244761at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="283"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="575"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="664"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="672"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO21607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1138" mass="126245" checksum="EBE12775F50E8639" modified="2023-09-13" version="1">MDSRRPPYQGHPPQAPPPPPPPPPPHHDPRQQQQQHQPANHHYAPQPPPPPPPSYHPQHHSGPPPPHTQAQGPPHQQQQHHPAPYQPGPPAPERLPPIQAAYAQQPTSASSTDQPTLPSFRQPSAPPQHDPRDGAPPEHYHPYNHNRSGHATPAPVNRSYSHDSGHQRSPATPAGPGPGSFPPSQAQDGAQQPPGQPPHHMEHGHHGYPPTNGHLPHGLPPPGPQHHPESHPQQQMTPMMDNHYQAYGPPPPNQQPMGYAQYNSGPVSTMYGQKRKQMRATQACEQCRQRKQKCDEGSPCSFCKENNLSCQYRDTPPAKTDKNMEKLLSYMEAHSAGLQELTNKIDSFEVRLRHVEQNAQRDGHTQRDNHTQRDSHTLRDSHTVAGAGIDEGRVQDEPLPVKRKPELDDHRTAPHKLLLLWPSVRPLLAAAHVEHNDGYVMEAEDRGVLRLWTRGEGIDENDGTQPGGPASPARSEDSGEGANAPTPHAEGLWGSGFPSTPGSDVRRSDPYGAGGLKPNGEIDLDANVVNRLYDSYMKSLHIMHPFLDKRRLRRMFDVFIKRYSTGRPRATFAVGMQHDSDHRPMKRQRSNGSTANPGTGSDHDMRREQTERSPGNAIIYLVLALGKICEWRDPLPSIVPDSKLQANTVVSHQISGMRGFAASSPISANIKPSPMSPKSTPTTQPTPPSEANLRLNDSRSRRSSVEGSPMAPAGPRNLDVIPGVAYYAKAAEILGDQGDGNDLVHAQMFLLAGLYKGQLARVKESMSWFSMAGRAIMILLDRYKLYNDNYWEAYGDVRRQHERAQNKIKDTRQSLIVLASWSCLQLESDILAELRLPSSNIQTIENLLLMPHKVDEVDDSYSGLDTDAKPEDYDTILLFYTSQLFLRRKLNQVHQEMYGPGCLGMPISAVQTMLQEHESLLSKWRDGLPDKLQWDDSDAPPSDILAARLRAKYWGARYIINRPFLDYALHIMALVRDGTPVEKAARDGHGNPRDKAEIHLFKAIQKLGDEQVWTAAKRCIHAAMQSTVAFDGVDGRLVVTNIHGTAHAQFGNMLVLSAAYESPLLGTWVPQERFQQLMQRTITFLRRLAPISPTSAADCGILEKFNKILFPTASEEPHVYKNEGVEAMSATASFGTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PG29</accession>
    <name>A0A9Q8PG29_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766147.1">
        <property type="nucleotide sequence ID" value="XM_047907995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PG29"/>
    <dbReference type="GeneID" id="71988725"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08847"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="608" mass="68430" checksum="42D2B3668C3C70AC" modified="2023-09-13" version="1">MFMTGVFSGIGFNGTDPEQERDAPPAATPVVFPQHEPRSSRKWKESGPPLRELFSKVRGPTDISTRHVQALNVRHKHTSSPDELIPLAPDGSSYLPPLTAEQAITPSTYAEANKIDSVSAKRRKAFDERLAELQIENDAGYRNINRTTKPGVKPPRVAWLRKFWEGLESMSQYWDTSLDEYYGGLPAHLPAQASAEKGHKRQRTNSSHPSSEVTVPIFGPETKRPPEPEDCPSVDEKLASKLQDDAAKTPLPQVDEDLNRASEHDNDRLSRSKSATPEPQSCLRYKGYRRASGRDMPDQFRTDTIRALVEAACWAFDCKVETPRKMPIVQMNKLNIPVRQTAQVYRIPRDRSKIRVGHLEGPMLTVQVRPETDFHAPGIDQAHSAMRDRLDLMREIGGLLQCAQERRREGKTEVRSGEGKWYTTKPRWGGGSGGEVENDVGNTDTLTKDVLGMAEGMLESAKSKAMRLRKRKTPAMLWKELKPSSLTWDAKTDYTAIGKEPDSPYDQIFMVSSLNHHISILKLTVHEAYLDFLETEKIPTHFRPDPPIPADQGWCSPRLERTQWYDLFNVDERVQAFRALWGAMAYLSREIERPTAGGADGADDEVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGB8</accession>
    <name>A0A9Q8PGB8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_09417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766271.1">
        <property type="nucleotide sequence ID" value="XM_047908565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGB8"/>
    <dbReference type="GeneID" id="71989295"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09417"/>
    <dbReference type="OMA" id="WHTRGIV"/>
    <dbReference type="OrthoDB" id="5537330at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO21905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27602" checksum="7C999C5CACDF9BBB" modified="2023-09-13" version="1">MALEELLAEFRDKEQTTDITKANWYNIAAAALAAASAGHEVVKLCRFATKDVDLETQKLVQRRIKETILKTSWLYGGPKAILSLFPLFKDLKEEETDHFGARWEAHLRNDPNETAEAEARGKLFFDKLWSPEAAKENLDFNFKHSPHLYLLVKHNLYFYASEPSILSFIETELIYAAALTCSNVPQQAEWHTRGIVRQGGTKEQARQVQELSLKMAEMYDCRTGKITPVDEIEWDDKKSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGF5</accession>
    <name>A0A9Q8PGF5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_09660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO21964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766330.1">
        <property type="nucleotide sequence ID" value="XM_047908808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGF5"/>
    <dbReference type="GeneID" id="71989538"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09660"/>
    <dbReference type="OrthoDB" id="3643063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO21964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="41670" checksum="5576026D1FDBD920" modified="2023-09-13" version="1">MCDRPEQLNDGMNSARLGTPMYRTGLDENLRSQLMREGRCFACRQRGHRISDNRCSTYPAMSSTHDPPIRPLRQSNDTENSEDPEPKANAMQEVTTTVELIERVLVQLPPDQLLKIGRTCKQFDSILKTSPTVQLALWQRASSNTTPSSWIWDGSKILADQDAKDFANANPATQQEERKIYAINPLLLRLPVTDPRPPTLHFLTKPLPRAFAVRLSFAKRNIDNATNHVLTRMDGAKIQQLPPYATCPSMQLTDPPVCKIIVVVSAECSSFVQMDMNGMPRLMNRKLERCTIEKEAGMLFRDVVEVLKGGSGGNRGTSRSNGLSGDVLSHLELPGGFPITETEMREYKVDLEKTTKIQKFKEEMAALVGARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PGP1</accession>
    <name>A0A9Q8PGP1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Inner nuclear membrane protein SRC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_09584</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766536.1">
        <property type="nucleotide sequence ID" value="XM_047908732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PGP1"/>
    <dbReference type="GeneID" id="71989462"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09584"/>
    <dbReference type="OrthoDB" id="2503928at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1180">
        <property type="entry name" value="MAN1, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013146">
        <property type="entry name" value="LEM-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011015">
        <property type="entry name" value="LEM/LEM-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041885">
        <property type="entry name" value="MAN1_winged_helix_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01261">
        <property type="entry name" value="Thymopoietin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63451">
        <property type="entry name" value="LEM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LEM-like" evidence="8">
        <location>
            <begin position="9"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="676"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO22170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="693" mass="76952" checksum="905637285D31FAB4" modified="2023-09-13" version="1">MDDQAYLEPDFDPNTLTVPRLRSILVAHNVNYPSSAKKSQLVELFTENVAAQARKLRNANARVKRTSMGIEDITTGRRGTGQGDSDEDIPPTPATGRSTRRTTRARTEEAIEVEPTHRATRHSTAPPEGITPRTSRSVSSKHRRTVEPVEEEPEEEPAQKRQSRTPRPAAVTPVVKRERADGSSPFSSDNVFQSGGGMGYTPSAQLRATETDRRRTTLGSTATARDLERRNRELRRRTEGVSAVKREQLDDTIVPTRRTFELPVSKVKQEEEIEPSEEFTAEEQLDLVQAQQSGELVPARRRTKRPGSSVKYGVGSVLSVLSLAVAGLWRQEKLQVGYCGVGSPSVEIGGVDIPPWLEPIRPQCEPCPAHAYCQELLQAECENGFVLTQHPLSLNGLVPIPPTCEPDSVRARKVKSVKQRAVEALRTQNAKYECGEAPAPEIKETALKAEISTKRRKGMSNEEFEDLWQSAIGEIVNADEITSNSDGQGNAQLRSFSLAALPLSCAVRRSLRETLRHYFWQLVAVLFVLSSGAYGRKRITSGNETESKAKQLASLALEKLSMQASLHAQDPDVYTENYISVAQLRDDVLRDEFSASRRTKLWEKVQKKVEGNANVRPMVREGRSGDVGRVWEWVGAVGYLESPEGGHSRRKSDRVSFAPVDMIEGGDVTDSSLMRSESKPKISKWEEGRGTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PH69</accession>
    <name>A0A9Q8PH69_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mannosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_09648</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766759.1">
        <property type="nucleotide sequence ID" value="XM_047908796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PH69"/>
    <dbReference type="GeneID" id="71989526"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09648"/>
    <dbReference type="OrthoDB" id="497541at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF2">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE ALG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO22393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="621" mass="69707" checksum="A38BC1CA5B03A753" modified="2023-09-13" version="1">MPPSRGGKPAQAARRPSRSPHRPTKLPSAPPSKQQPCQVQPIVAFYAFFFSHAVAACFHPIQDCDEVFNFWEPTHYLSHGHGFQTWEYSPEFAIRSWTYTSLHAVITPLARLLPVVSNTKTAEFYLLRFLLGFFCAVCEARLFSKVSHVLNGRIAIMFQFIITTSPGMYHASIAYLPSSFAMYFVMLGTAAFMDWRGGLRTAQGIFFMGVGACLGWPFAAAMSISYLLEELFLASVSDLQGLTDLFYRVADGIMRTLGVLLLQTLVDWHLFYRKFVLVPLNIVLYNVFSSKGPELYGVEPWHFYLRNLFLNFHIWLLLALVSLPLLLVQHFSRAKGATRSSYLRGIVFLLPFYIWLGIFTLQPHKEERFMYPAYPALALNAAVASHIILSNLGSTDPKDLISKIPVQLRFLPILATVVGAMAISAFRVAGTITAYGAPLAIYAPLHDTGVANVGDNVCLGKEWYRFPSHYLLPEGVKAKFIRSDFHGLLPGEFSEAGRGFGLFPGTHLIPAGMNDENQEDLTKYTDVKGCRFIVDSHFPTTEATALEPSYIHDVEHWEEVKCLPYLDAASTGIIGRLGWVPDLPFVPAKFRRVWGDYCLLKRKSSQRQPGRAEIPNKETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHF2</accession>
    <name>A0A9Q8PHF2_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_12222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766894.1">
        <property type="nucleotide sequence ID" value="XM_047911370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHF2"/>
    <dbReference type="GeneID" id="71992100"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12222"/>
    <dbReference type="OrthoDB" id="3364440at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="124"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO22528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="453" mass="50058" checksum="DC1E5FFE53A33CF2" modified="2023-09-13" version="1">MPPSPAPVTVLEQFLAREPGTIMIHLHWVDLCGILRARVLTKSRCQKVAASGQPARGLPRPYLGHTDCNDMPESYLPATRSLLCPDWTSLRWIREGHASVMCDVREDNESYGDCDPGDTFDRCSRYALGRIVRALYAEHQLTVIIGIEIEFFLVDKPSPGDWPRIDTVQAYNHASQASSVRDKAEIVLVACIQHLERCGISVEQYHAEGGSQQLEISLSALEAIAAADAYVRSKEIISNAASLHGQLATFLPQPFEGAPTSGLHVHASFTKGSPDSQHANIPHFIAGVLGRLPLLCAFAMPSEDSYKRVSSLVTGTWVSWGTENRDNPVRRIEDNHWEFRAIDCMANIYVVLSAYLGAGLLGLQEDEHLRWGDNRHFQHRLDDAQRTQLGIGPEQLPTSLQEAATLLRSDMRGLDAVMGPKLVDLFVVVQEAQQVLASRMSADTRAALAFDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHU8</accession>
    <name>A0A9Q8PHU8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767094.1">
        <property type="nucleotide sequence ID" value="XM_047911279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHU8"/>
    <dbReference type="GeneID" id="71992009"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12131"/>
    <dbReference type="OMA" id="EFAHDSA"/>
    <dbReference type="OrthoDB" id="10502133at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="221" mass="24264" checksum="F639F121D726E3F9" modified="2023-09-13" version="1">MAGDKRKADVFGKNHTLGRADAKRAATFSSVGEFAHDSALSTNPMTRGQYHIDHSRTQLQTITPAKSPQKQNVTISDVDMEMVDSDAACIETFRHSLNDFYQYHNHLFGPAHQTDLKNAYHDILLDSSPARVLSAGEAFVAKLHGYVQDLQQAAIQQIRWRASTGSLGASREVLAATDAVLSQLDAQIIGIGAEAERLMQEVGMLRDQYQSPALHTVTSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIY9</accession>
    <name>A0A9Q8PIY9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12845</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767679.1">
        <property type="nucleotide sequence ID" value="XM_047911993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIY9"/>
    <dbReference type="GeneID" id="71992723"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12845"/>
    <dbReference type="OrthoDB" id="43906at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </location>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJD3</accession>
    <name>A0A9Q8PJD3_PASFU</name>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2" key="2">
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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            <dbReference type="EMBL" id="UJO23464.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="494" mass="56117" checksum="89D459C46763FBB1" modified="2023-09-13" version="1">METANDTRSNQDEGYTNTGSPSRPAKPYSLTNSTARSMIPPQPEPTPTRELDILAESASPDREQPRETSGDASVFSFRMPCLTAARFARDTNATPASTYTQATDLSNQTSEQRSTVLKRSRRLSDGAKVRELASIQQQQKALDAEEVLLQVEREAFEVECALSGATWALLQREMFGGKLKSHRPSRPKKLAVYTRVPAQQTLSALSHWMPMNASLGGRRTKARYLFDAEGSASMVFHMFTRMPPELREFVYELAIPAGHVSLRSTGHHRFEKVVIPAWTNLAFVSRHMYLEAKRFIFERHTFILNVNMGTTENNSINTYQLPAHAEPWIRHLVLVVDCTRAPSRAHLAEADWRFLQRMTRLKSIRVCLLHLRKSHLRPTQDRRLICSEVVRNVMMRVPAGCEIVFGARGQGVRDHVEDMKTKCAKRQETDPVSWVPAHLGRVTDVSRAELKAAKAQFESDITLEKGRMHGYANDFRHRDRYLRGWAELPFAEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJK5</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">Race5_Kim</strain>
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    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050197">
        <property type="entry name" value="Aldolase_class_II_sugar_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789:SF0">
        <property type="entry name" value="3-OXO-TETRONATE 4-PHOSPHATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22789">
        <property type="entry name" value="FUCULOSE PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="3">
        <location>
            <begin position="8"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO23721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32807" checksum="F5E1C920DA79E4C5" modified="2023-09-13" version="1" fragment="single">QRHTEPREGHSQTAPSSHCHKVVDAFGHISVRNPQNPKTFFVSKSLAPALVSSREDLEEYRVEDASPVNEDAPKGYAERFIHSEIYKKYKGVNAVVHAHSGSVLPFSICSVPLRPVFHMGGVMGATVPVHDIQNHYKSIDPLHSLLVNTQHLGEGLANGFNPSTRTSKATSLIKNYITSIRPPPVDFPAHPTVLMRGHGFTCVAASIEEAVYRAIFTCTNARVQTTALLMQGGYNQGLIAERFGRGEEGGQAKQEGIRFLSEREARDAWTANERHAERPWGLWCEEVRGCGLYRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJX8</accession>
    <name>A0A9Q8PJX8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">6-methylsalicylic acid decarboxylase atA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_12856</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768267.1">
        <property type="nucleotide sequence ID" value="XM_047912004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJX8"/>
    <dbReference type="GeneID" id="71992734"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12856"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000153">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="304"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO23901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="430" mass="47412" checksum="2C6FFDA817955473" modified="2023-09-13" version="1">MAPTYKPDPRNYSIAVVGGGIGGLCTAIGLLHQAINVTIYEAASRLSELGFGVSLAPNATRALQLIEPAMYAGFLKARTNNAWPDRQQFWFSFRAGEESMSDGQNYGKRFFDQHCETGQSSVHRANFLDELVALVPKEIARFGKRLVDLEDNGEDVTLRFADGSTARHSAVIGCDGIKSVVRQFVLGKNDPATYPVVSGKYAYRGLVPMEEAAGVLGDELARNSQIYVGHGGHILTFPIQGGKTMNAVAFGTKEDGEWRHPEWVIPMDKEAMLEDFKGWIAPAQQILGLMRKGDIWALFDHPPAHTYTKGRVYLLGDAAHASTPHNGAGAGQAVEDALILAQVMALVYNKKDIPRALSAYDKVRRPRSQRLVKESRVTGLLYDLQAPKVEDDLEKVAASLKVNKIWLWNHDHEAEIKKVQQVFLEESAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PK34</accession>
    <name>A0A9Q8PK34_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_12832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768294.1">
        <property type="nucleotide sequence ID" value="XM_047911980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PK34"/>
    <dbReference type="GeneID" id="71992710"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12832"/>
    <dbReference type="OrthoDB" id="5389734at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="646" mass="71573" checksum="B58069865366A9C9" modified="2023-09-13" version="1">MAMALAAHYDSGSDDEFHSVSGRDEHDDSESTLNMPPVHPIAPLQGAFEESIYESTQNEDDSAAESPYDAEMRRRELLDATRYEDVRQNKWKQKHGAKYHPLLKLMAQIVFGMHLLQQSQAKSNEEVVKILQNHVTDVDSFLERTSEDFVLATNDIEERIRYLKLPMQHMEVFNVMLDEKKFRADLVNGNDKIEMIVGRTAKAVNDALFDISSGLESTKELGTYLSKVIDEGLPSDTEIADVFAAMRGNEQGWMKYLQELRIKGENLGNSLVALGNVIADINKHAAAASRRNKPQSRTISTTTTTGSSSPALRSKFAKDSVVYRKPGPWLDKPLPSEPDSEFSAAKVSMPKPHPVPFATRYEQPREHAPIPGSRSSNAGDATPSQRRATSRTASGPLSSNPPDAPPDASPRVPYKNPGRSQSQSTAHVLRPSSPQRPVASFRRSRSQGAILDSQTPNKVIPRKPVAGTLRKHPGTQIKYVPPTGVTPAKEYTSITNGFSRRIFMKLRNIPPLPQSRQRTEAVARPVDSAYSSDRKRSTSSPTEFTMDTEHDIEKESQSYFEKDAVAGAGDAIASTRLGLFPKDTGPLAPSQASMRSRHDMPNSKAVSSAWTDRSLTTTHSSKAFRTMSIRKFFGHHKDESRNLPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKK6</accession>
    <name>A0A9Q8PKK6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO24094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768460.1">
        <property type="nucleotide sequence ID" value="XM_047912438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PKK6"/>
    <dbReference type="GeneID" id="71993168"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13290"/>
    <dbReference type="OMA" id="AECATSA"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="217" mass="23752" checksum="324D95119F0B5C4B" modified="2023-09-13" version="1">MDISTSHVFDFPMPPSAPASPRSNRPSMPRRHTIVLKAEADDVSGPPAPARAPPPIPKQCEEIIFRNPWLQDRPVINESISAMFHPVMHLNSAPESKFSVDSSCWGEDHRRDSLALDEPRQSQSSSCAAECATSAGDSVTNDPRMRSHSHTTDYDVEDEMFFSTMQALLTMPPPPVDEDLTPTETLPILAPARSDFVEGLKFVLSGMSPAASGWPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLN5</accession>
    <name>A0A9Q8PLN5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MHYT domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
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        <location>
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            <end position="70"/>
        </location>
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            <begin position="122"/>
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        </location>
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        <location>
            <begin position="158"/>
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        </location>
    </feature>
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            <begin position="231"/>
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        </location>
    </feature>
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        <location>
            <begin position="13"/>
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        </location>
    </feature>
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        <location>
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            <begin position="717"/>
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        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO24707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO19283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="75" mass="8455" checksum="874FC02E3C3B4222" modified="2023-09-13" version="1">MLPPESESKQVVAVYFLAPFSQHDDGTLKALSVMRPGTVRAVLIGFQDSEMIEDIKILQKKCKKNRLERRNALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URA3</accession>
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        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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        <source>
            <dbReference type="EMBL" id="UJO19511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="404" mass="46449" checksum="F90DC8F1397F3E24" modified="2023-09-13" version="1">MPPTKRKVDDAIHVPRKSSRPSITPDRYGQSSRADLQEKLQYDQQSSMTIPSLSVDSIEAIFEEYDRLVSFMPLQRSGSDKEVLRRHKEIEKATAAIFDIHQRAQEKITALCQQINWHTMWQHPGWKDPKWYWNGNIFDLDGEQICATFEEHPIQDTSDFRRYLARVMNGNLPKGDTGSYCEYDEKITAIMTSVGRSHDPRASFNTFQLSNTILEGVTCTKYKGENVLPTIMRRINESESLREGMITRIRTCLRNAGGEYLDCAAARRSIWRSYASALSQDEDVHAYHDCVHGYLLRILEQLQLKAKEGIRRNTYLAVGTKLPTELADLVLNAALLAEEVPLGTSIAEEVEVVYQPAEHWDKEVLRRKKVLEKYSCVFVQYDRSDDPTRYGGMFRATGFARRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URJ2</accession>
    <name>A0A9Q8URJ2_PASFU</name>
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        <submittedName>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="71990352"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
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        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
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        <location>
            <begin position="177"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO19869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="315" mass="34261" checksum="6A3F3F1CCFD8629F" modified="2023-09-13" version="1">MSSKNPGAGHESAPVEVSWLKRDVLLFAATIGATAEELHYLYELHPNFAVFPTYAAILPFKNTQQEVVDFYAAQHASRPSIPGVPQLDSKRVLDGERKMFFHKPLPVTSAGRKFESRSRVVGVYDKGKPGTVLETQIDIVDKESGEVYVSVIGSAFFVGQGNWGGPKGPKTENFPPPEGKKPTAVHENPTSAETPILYRLNGDYNPLHIDPKPGKAMGFGGVITHGLHAWNSTAHALVKMLGNNEPGSIKEYAARFASPVKPGDVLVTEIWALGDKDGEGWENVRFQTKVKSSGKVCLSNGRARMKVSKEAVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URN9</accession>
    <name>A0A9Q8URN9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_10434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO19917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764283.1">
        <property type="nucleotide sequence ID" value="XM_047909582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URN9"/>
    <dbReference type="GeneID" id="71990312"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10434"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="21"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="356" mass="38954" checksum="7C53D72C4347D710" modified="2023-09-13" version="1">MASNHSTTRRAYRRTDDFTPGTTKIKIAEEALPLPLAATSVLIKVHAVALNYRDASISNGGNPWPVTPHEVIGNDAAGEVIAVGDQVKTLKIGDRWRRSWLAADEDGVLADYLVYDEKVLGKLPTYLDWVQASIVPCAGVTAWSALKGAEIGQSVLIQGLPDYRRRAYDVRLTKFVTGTGGVAMFAPKRARSMGLKVILSSSRDKKLKNVCDLFTEPPILTVNYATNAEWHEDVLKHTDGAGVDLIVENGGPGTLLKSMKCTRRGGTISQVGHLDRQKFDDALEIVPTLIDRRILLRGINAGSKTDMDDLCAALTATSIRFDDIIDSTWPFEKADEALQCLWEGKQIGKVVIKILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8URP8</accession>
    <name>A0A9Q8URP8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_10100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764400.1">
        <property type="nucleotide sequence ID" value="XM_047909248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8URP8"/>
    <dbReference type="GeneID" id="71989978"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10100"/>
    <dbReference type="OMA" id="WIESMPD"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058268">
        <property type="entry name" value="DUF7962"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25907">
        <property type="entry name" value="DUF7962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7962" evidence="2">
        <location>
            <begin position="105"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO20034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33412" checksum="9F0D8F3390F5BD43" modified="2023-09-13" version="1">MAAKVIHFDYEFSPVGQKTKLVLKAAGIPFERCDQPALLPRPSLEALDITYRRIPLLAIGKDIYCDSELVIKVALEQLGKLPTSLADKAFKEWGDNVFSDVCLLIPAEVLTPEFNKDRGAVNFMSIQRPDLKSARPSSLAQFQGRLKQIEEHFFLSGGPFINGANISLADIEAVWPVRWAFKYLGVDKDAGVGKDKFPRVWKWIESMPDVTAPEISAEDTHASIRGAQYTAKEIGIAKDDPTGLQAGTRVNVESFDTKAGAYPQAGKLVGLSDEEIVLELKDGVRLHFPRVGYLVRDANAVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8US10</accession>
    <name>A0A9Q8US10_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_10038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764656.1">
        <property type="nucleotide sequence ID" value="XM_047909186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8US10"/>
    <dbReference type="GeneID" id="71989916"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10038"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="168" mass="18456" checksum="DC6F7AB632110893" modified="2023-09-13" version="1">MPQDTTNPSQPISIRPRTAQDLPACISILRRVYSLDKYPIQGTSNATSFLAFATLEQAFVATTSDGIIIGHVAIGTASDDDVAVKLWRSQHPETEVAVLERLFVDPDSRGSGAAARLIEAATAWNKEWERRLVFFLLYRRLGWVQFGVGSYAYGDGESMDALCFVSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8USI6</accession>
    <name>A0A9Q8USI6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Non-canonical non-ribosomal peptide synthetase FUB8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO20874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765240.1">
        <property type="nucleotide sequence ID" value="XM_047910154.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990884"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11006"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="575"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1359"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1170"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1496"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1177"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO20874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1765" mass="194876" checksum="A95906AD56B60C5B" modified="2023-09-13" version="1">MDALTDFLNLPLPDYIDNLAINEPDRVFARVLSASSTGYSAVEVTVQGLAVSIDIAARWLDEQLGQDGESKTIAFMAAGQDLRYFIIMLGAVKSGRLAFFPSPRNDVEAQCSLFNEYRCKTLLLPRASSFHDKLQPVIEQLALNVLEMPSLHYFLHNGGGLRRGYGWMPEPDSDFKLQPLVGVHTSGATGSPKPVVVKHGNATAMEHWKRLPSHFGHGKVHFTHWSSKTILLALPLFHLAGLNIMMAALQNNTIVVLPPTGLGPLSSDIIGDVLGQVTADWLVTSPSILADMASDVKLSSSFLKVEGVAYGGGPLSKAAGDAIVESCSVLTFIGMSECGILPSQLVERDDWQYIQFSPALGIEMRPYVEGLHELSFVRDEAYKDFQVPFFTSPEIDEYSTKDLFSQHPANPDLWLWQGRTDDIIVYATGERFNPADFENTISGDYQVNAAILYGNGESQSALLVEPHRSLVGVRQSEREIIQAIWPTVEEANAKCPSYARVRRDMIVITDLRKPLPRAGKDTVQRKAALTLYEQELDALYSRDTMQGSVPDSPYAVEERKPHVYIRNDSPIDTHDDVSPDERQMMQQILDIVERHTDLRLHATDDFFAVGLDSIGVAGIVKRLRKLIAIHGDDKEMEPKTIYNHPTAAALARYLAGKELVKPGKLSSTEELYERYSFNPPVTTRDPIPYDSLRRIVALTGSTGSFGTYLLDRLLHDDTVTHIICLNRKHNAEAMQLQSLRSKGLQTNFKNKVTFLTVDFSKQYMSLDRDTYKNLLTIVTHILHTAWHVNFNLPLSHFEKPHIAGIRQLVDFSARSSHGAMIIFLSSVGAVSNYRASLDGENHRTVPEDPIEDWSCASRSSGYGQSKLVAERILYTAATEADVPCTIIRFGQIAGPSTGMGVWQKWEWLPSLVTSSKYLGCLPATLGAFDVVDWVPIDSAAKIVGEFLHDATTQLQESGEKLMVYHAVNPNVVAWDTLLPSIQPHLGVYDVVSSHEWVELLAESDEKGSPENPAGKLIPFYRSLVDSEMQVPLDITMSRQASRTLAELPSISGDLFESWVRKWIYGRPVILSLSPALPKLVPQAVFSGTGRLRSCESMLLLATVTLLLKGQFAEVVTSAIEADRRQSRHALRVNGNGRRVDRDVLLIVNLSLGHYVLRCFQCGQPREQPGDMSKFFRSADSSGSDTDSSDSDTGAGSTAEVSRDGALQSLSNQSHTLGPDILTDGKDWLLHSLLEERCLNQVRAEQTHARSLDDNGIRREARKRYRALVARLAPLNLVSPGLDDDRHGPIRQSVRDILDSVGTDTTGALQVAPRTPLPLRRMLTEGNDPVTPSSPISTILFDTLGTVGCSAATPRYVGDFEELGALGKGGYGEVFHVRHHLDQREYAVKKVPIRPAMVSRILAEGKSALDDVLAEVQTLCKLEHPNIVRYFSSWIEWSTPKPSSFEGSSFSLSSQQLRDVVGGAEVSTSFSHSLHRVRTESDGLSDNIFESRSHDSIAPSVSAHRSGHEESSSRSVTGAALERFSGPALTLHMQMDVYPMTLADFIAPKAGSSGILPLAHCFHLETSVRILLAILDGVEYLHLKNMIHRDLKPANIFLRHEDNPRATHNVDLLLCSECRRAGKPQPAKLSVRIGDFGLVTNVAEQIHSSPGAAGTELYRPKTMGLGPQLDIHAVGVIACELLYCFNTQMERKSILHALRDGHIPNRFTTCVGTQSNKARECIKSMLTHGNENVSLHEIKHRLSQLIAPPSFSALSLNDEVTRRSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT11</accession>
    <name>A0A9Q8UT11_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Highly reducing polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_10780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765676.1">
        <property type="nucleotide sequence ID" value="XM_047909928.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71990658"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10780"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF18">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="844"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2236"/>
            <end position="2312"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="844"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1010"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="876"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="2317" mass="252688" checksum="DB043A8EFA230F6A" modified="2023-09-13" version="1">MFIEDIDPKTFDAAFFGINKQAAVAMDPQQRQLLEVVYEALENAGIRLEDVNKKAIGTFVGSYAVDYADVRARDPTDRAPGVTVGVGRAILSNRISYFLNTQGPSMTIDTACSGSLVGLDVACRYLSNGEIDGAIVAAANIYLSPEHAMDTGVINGAMSITGRCHSFDARADGYIKAEAVNAVVIKRLADAIRDGDPIRAIIRGSATNNDGRTGGITAPSPEAQAVAIRNAYANAGITDLNETTYVECHGTGTQAGDPAEAQGVASVFSETRDPRRPLTIGSAKANIGHSEPAAGITGLIKAVLTLESDSIPGLPSLQTPNPQIDFEGSKLKISRDAIPWPEVQFRRASVNSFGYGGSNVHVVLDAPTHEQRQSFQFSHQSHYTGQLLDNGRPRERHQLLVLSANDAEALHRKFQALANHVLNPSVSIDMRSLSYTLSERRSHLFHRGFIVTDTTALDVGRLVTGKRRSKPPAIAFIYTGQGAQWPQQGKALLELYPQLTQLILDLDDVLAGLPHPPAWKLIDELTLPRTAEEVQRPELSQTLVTALQLALHHLLREWNVLPTAVLGHSSGEIAAAAAAGLITNAQAITLAYYRGYAAEGAAQSSGYGMLATGAGAVDVQPFLEGLEDSIRIACHNSAKSTTLSGRAAGVFARPLHVNVAYHSHFIGEVTSRYQELITPHLSEFDCQSAGPLMFSSLTGRIRDLEVDAHYWAKNMASIVRFDEALTQLVLDTNVSIDFLVEIGPSGALAGPVKQVLEQAGRHQDVTYTPAFARGKDAIRSLVECAGRAFIAGTDVNILRVNAIDERSRPAVLVDLPNYSWDRSQEYWYESESSADWRNRLHPHHELLGSKVLGTSWQEPTWKNTLRLQDLPWLADHRASRSPWLMMFRADIEAQIGSDILFPATGFIAMAIEAIQQQHEALTGLTSQTSLHGVRLRDVKFDRALPFLPGSDVRIRLTLRPRTGGKSEWHEYNIASFALEKWQEHSSGLIRRAHSEEASHYAEGAAAQPLDRPVPGTLWYKAMRDVGYNFGPSFRTQKAISAHIGQRRSRSLVSLQEPALQRPASRYLIHPAPFDGCIQSTAPAMWEGVRWHVNELLVPVSINDIFVSSQLTSSIDEARVEATADYSGAGRPESAKSHVYHVSVHDASSQQLVLQVSGLSHSIIERPPSVYDNHRYSQMHWKPDISFDRPVYKASSLSPMHEYIELILHKHSRLSVLEIVHAQDVAQSLWLDFPSKFREAASSFVLAVPGLDELIDFQTRYSTEPAVEDFVVIERTLEAMGASALTKRGNSKFDLVIYRSDLDRDAELVKSASRYVERGGYLLWSQEHAASLDTDHVRIDGHDSPQELGESHEKLTDDSTDTIRKANFETLRQVGLRRIQLDIPEILLRGSHTLWADDSESRLADVGGTLRLSALTQPGTAVDGLLDGLAQAGWIVVPDDQDLTERNSSPISLVIEAGEPILPDISKEDWSSLQQLLTSGVPILWVTEGSQLEAGKPHKALIHGLRRSAHAEDPSLELITLDVEQIDGPNTVSAVLEVLRRYQAGSLKGKGEDFEFAEREGAIYVPRVVPDAQLNTAAAERGRSGRGAPPIQKPFSSFDARVALHCERPGDLDSLTWQEEDVTVELATGTVEVEIMAVSLAFKDVAVAMGLVPENEHVMGLDGAGIVRRVAGSGVINLRPGQRVVVSGHGVLANRVIKPACRVCELPDWMTFEQVATTPFVTALYSLEGLARLRKGSRVLIHSASGALGAAVIQLCRVAQAEVFATVGSTEKKEFLTREYGIPEDHIFSSRDTAFAYGIQKITAGRGVDIVLNSLTGELLEESWRCIAEGGTFIELGKRDLLDRGYLPLHPFLRNSSYRCVDFGHREMPDELIGETLQKAVTLLDQGVLKPIEPVTVFGFDQISAAFRAMGGYHIGRVVVSRSADRDVVLPVRPGLRHLSLDSEAAYVLIGGLKGLNGGIAVQLALWGAKTLVVLGRSGYNDEKSQSVLRELELLSVRVVLIQGDIAEYSDARRCLDAAGPPIRGIIHAAMVLRDRVFASMTHDEYHQTLRSKVQGAWNLHRAAEELDLPLDFFTLFSSISGLIGQKGQANYAAANAFLDALADYRRVRGLPACSIDLGAVDDVGYMSEHVDLLKALDTNAWTPINQSLLHEILRFAIEQQDKDAQINPSSSAQLVTSISHRQKPGYGLLSDARFGALGRGQAGTDGAAADGIAAEAVEVRAFQTLIRNGPNSPTVSLQLAAVAAIKAQIAKILQSTQAIEEERSLGDYGIDSLAGVELRNWIRSRLGVEMSTIQVTQTPSLTALGSEVARLASRTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UT43</accession>
    <name>A0A9Q8UT43_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA topoisomerase 2-associated protein pat1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_11557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765766.1">
        <property type="nucleotide sequence ID" value="XM_047910705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UT43"/>
    <dbReference type="GeneID" id="71991435"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11557"/>
    <dbReference type="OMA" id="YLEHSGH"/>
    <dbReference type="OrthoDB" id="74835at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="484"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO21400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="816" mass="91461" checksum="6AD3BA3DF8BA3C2C" modified="2023-09-13" version="1">MSFFGFDTNLPGDRRGGQGMFDRQDPFGGLGDGGDQEALDFDQTYDGLGQHLQETGDEDNDDTFGGDMPVTRDQLGKDFDFAGQTANIRDTLLEEQVLHQARQPMQQARAPKPARTGYEAYKQPDYMPKLEADASIWGTSVTKKQAPQVQQEQPLAGSAPKMMSLEEVEAMMRANARPTPLAQQPAPDVHAQTLGLKNMLGLGGPPSGAPTPPAQQPQPAFEQQQQRPPQILQRPQPPQENQQPQPDYNLRAPQILQRQHSPANARPQSQDFNGQPQFQHGPPPGMPRVGGHTVPPHVRHQQQNHQQHGHNRGPSYSGPPITQAQQLMQMAPEEREAYLAEEAKRAKRNHKIFLLSKNNGLMTPQDKNFITRIQLQQLLTATGGIDNEQGSEEQLAEDFYYQVYASIRGPPRSGPGQPLNQFAQTYLFQTGSRYGYGRSRHHPRGGDNHVQRMEQQVARAVEAAKARPKNKQLVMEGSLGKIAFSNSKTPRPLLNIKRPDSAHPQMRPPKPADRKTALRNIESLYSTLMRLEDHERKLPPPPNEDSPPDVIEDHMRWRSEMQELNQQLWETLKVMEPIQPNPTTPHPFIQLLSHSKGKKAIPRIFRHLDDNQRLTMLTLIAIHLDILDVIRDAYPPADNSPVPPRVKEEVFTFEQAVLPPLYSYISEAPLNIIIGLVGLVLDRVHLQAIVRTKIGVLILTAFINRAELVTQQQGPSDDWSSHYGRLFDTIEPVLPYMFPTETNLAASDDVHIWHFLATVGVGASPDQQQRLVLGVKDRVMETVAVSKTLPEEMSQKRLGDVNLFMRAIGLDVELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UTS7</accession>
    <name>A0A9Q8UTS7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_08848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090171">
        <property type="protein sequence ID" value="UJO22135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047766501.1">
        <property type="nucleotide sequence ID" value="XM_047907996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UTS7"/>
    <dbReference type="GeneID" id="71988726"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_08848"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO22135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="176" mass="20108" checksum="34768F9AEBD793F4" modified="2023-09-13" version="1">MVYLLPRPQQRRDPEQDPLALFSQTRQSQHTGTHAGDFYTRSLSSIYHGVDFTGTTAIDELTLAIVFPKGERSRWAPLVKYLNDTAGILAPSLINIIALAVRNVGDAILDMGFKYEARLAVAKAAQAVQVMGSCVKRRRQGDLEVEYESLKELKPVEKVSMHEERWWISWIRWFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUU2</accession>
    <name>A0A9Q8UUU2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_11944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767611.1">
        <property type="nucleotide sequence ID" value="XM_047911092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUU2"/>
    <dbReference type="GeneID" id="71991822"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11944"/>
    <dbReference type="OMA" id="IAFRFHK"/>
    <dbReference type="OrthoDB" id="5376498at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO23245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="175" mass="18978" checksum="B02E4E7A45279EBC" modified="2023-09-13" version="1">MATMQATPRPHTLTLRFKQQRTTILLEVEPLQKLSEIRALLLHAIQQTHQSGNINGQDIPQNSDQVKLGKAVDRHNLKLGFTSLDKELPEEAPTGKGKGKVSATNKSATSQLKDCPQGVGLKSGDVVAFKFADQDEAAMVDMEGEIVEKWDVSIPTLEEAYGDEGGDEGVGLEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UUX8</accession>
    <name>A0A9Q8UUX8_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="10">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_13349</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="10"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767805.1">
        <property type="nucleotide sequence ID" value="XM_047912497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UUX8"/>
    <dbReference type="GeneID" id="71993227"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13349"/>
    <dbReference type="OMA" id="NVSCNCI"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF33">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="12">
        <location>
            <begin position="173"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO23439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="544" mass="61160" checksum="08B7CA42B2F1B429" modified="2023-09-13" version="1">MASTATSATTDTPPKLLKKAGTTDTNKIPSTPMHTTFGCTHIKGLLEQARKQAIDQYTKAIRVVKNEDNFADRYYKNADGPSCTIRVTYLCLQCPRVSATRERHSKGHGFSVESTNGFIYCHECEDFIYDPTFEEIRDTKSKKRKQSDSLSESDRKLVASNTTATPCAATGLRGFYNMGQTCFMSVILQSLIHNPLIRAWYLCEGHKSSECERDCCTSCSLDDIFTDFFGSEKHEGYGAVHMLQACWKGGGSLAGYSQQDAHEFLGFILDSLHEAITDSDEKEDGNDTQKKTESCDCIIHQTFSGLMRSTVTCSECKNTNTTSEPFMDLSLDIKTTGFVTKKKKLALTNAVQTIKEAIPMDLRECLDRFTSTETLTSENYTCRKCNAPKEAKKKLSLTQLPPVLPIHLKRFAHSKTKAESNKVNTTIRFPFSLDMSPWLSKETKAPTTNGHHPEKNDDSDDGDTIDVKPAAKKDKKEDSEPQKPIFELSSVVVHKGKIDNGHYISYSRQGNEWFRFDDEKVVQVEEREVLQAEAYMLFYVIAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV39</accession>
    <name>A0A9Q8UV39_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_13228</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767955.1">
        <property type="nucleotide sequence ID" value="XM_047912376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV39"/>
    <dbReference type="GeneID" id="71993106"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13228"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0858">Xylan degradation</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="12">
        <location>
            <begin position="64"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO23589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="150" mass="16147" checksum="40E0FCB3D66906BF" modified="2023-09-13" version="1">MYSFDPASQKRINRHRQSSRLHAVTVLFISSLIVLTTSILGALAAPVTNPIEVIDANITSFEARSTAPGTGTNNGYFYSFYNDNASGTVTYNGSAGGSYTTQWSNCGSFVAGKGWNPGRGRTIRYSATFSPSGNAYLSVYGWTTSPLVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UV87</accession>
    <name>A0A9Q8UV87_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Meiotically up-regulated gene 70 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_13260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768016.1">
        <property type="nucleotide sequence ID" value="XM_047912408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UV87"/>
    <dbReference type="GeneID" id="71993138"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13260"/>
    <dbReference type="OMA" id="SAVMVCD"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="90"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="157"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="326"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="467"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="571"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO23650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="71660" checksum="FE2497FE728A7FF6" modified="2023-09-13" version="1">MSTMSGQRGTPKGKSEYAQGSGGTLSGIPRPKLESTISDANTSLSASRAKTSKRDEALRKKLEGDLSKKRGAAGRARQTRKAPPGTVLALRPNQALQIRPNTTVTEAAQMMAAKREDCVLVTDDDDRIAGIFTAKDLAFRVVGAGLKANSVTIAEIMTNNPLCANTDTSATDALDLMVRKGFRHLPVMDENHDISGVLDITKCFYDAMEKLERAYTSSKKLYDALEGVQAELGSSQPQQIIQYVEAVRQRMSGPTLESVLTGLPPTTVSVRTSVKEAAQLMKENHTTAVLVQDQGQITGIFTSKDVVLRVIAAGLDPVTCSVIRVMTPHPDFAPLDMSIQQALRKMHDGHYLNLPVMNKESDEIVGMVDVLKLTYATLDQINGMSTGDNEGPAWNKFWMSMDHGDTESMMSGEGSHSHAPDARSGMMSPEVPQRLGFERGDSVLPTDSASHNGGEDEASALAGAIEDKPFTFKFKAPGGRIHRLQVVASAGLAEFVGHVAEKLGHEADSIGGVPTFEDGKLGHAGFALSYMDNEGDTVSITTDHDLLEAIMMARTARKDKVDLFVHDPEKPALPVTVDPQPAIIPPTPPESSIRHRKRYESSDEQEEEDSPSVRRRERKSTAPQPAKAQEAIIPGVPNELLLPGAVLVLGVVIVITFTLGRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8UWP4</accession>
    <name>A0A9Q8UWP4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 12B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_14401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090175">
        <property type="protein sequence ID" value="UJO25223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047769589.1">
        <property type="nucleotide sequence ID" value="XM_047913549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8UWP4"/>
    <dbReference type="GeneID" id="71994279"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_14401"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF81">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14040)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="624"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO25223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="660" mass="72829" checksum="F932C83038330B6A" modified="2023-09-13" version="1">MPPRKKQKVEDPTPPTPPYSKAAPPKPPAGVDVHKIIVGVDFGTTYTGISWVSSEGLNVKSLDEVHCIRDWPGPKGDADYSWKTPSRVAYGSENDGDINVWGFEVLPKMKSYAWFKLLLDPEQASKFDDPGLNTSEGQGVLAKPSYKSAVELCADYLCEIAAFAHKYFVKRPSAEVLAATPLEFYFTVPAVWSDKAKSDTLRAAQKAAKMAKLKVHHDSQLFLIREPEAAAIATISSLTFGGSTQQIKAGDSILICDCGGGTVDVTTYEIESITPKLSFKGLVVGTGGKCGSTYIDRGFIKWMEQKFGDAYMNLSWQKRGPASRLMKDFEGHKRDFGNSQDPDKYYKMQCFMRDAEDSKYYDDDGVVRIYNEDLRKLFDPVVAMIIGLIESQLEAEKRQKKGKVTIKTIILVGGFGDSVYLNDKLREWCQKAQIRLICPEHPQAAIVRGAALSGLQQIQPTSRRARRHYGFCFSLPFDRVRHRAQDKYIFAWDGSARADGNLCWEMAKGDLIDEDTKLTSSFHSLVYEDSPGSHSSTIYSCDLDDPPDHIRVPGAKKVAQMKMDFKSLDLTQYQSRWHNGRLLRKVDAEFQIHFGTRRGVLEFSCVAGGKQIDNATVSFDGQDGAGASSGVGHGSSPITVVASGDTEKGTSSAPHKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1P8YXR7</accession>
    <name>A0A1P8YXR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ecp33</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Extracellular protein 33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ecp33</name>
        <name evidence="4" type="ORF">CLAFUR5_04595</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Novel effectors identified in the apoplast of Cladosporium fulvum-infected tomato.</title>
            <authorList>
                <person name="Mesarich C.H."/>
                <person name="de Wit P.J.G.M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">0WU</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
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            <authorList>
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                <person name="Chen L.H."/>
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                <person name="Stergiopoulos I."/>
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        <lineage>
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    </evidence>
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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
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        </source>
    </evidence>
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</entry>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="510" mass="56853" checksum="B17951294242C1B3" modified="2023-09-13" version="1">MDFMDRNYDQEAGYQFNLGTALLHETRSSSWYAAGLLARNEGNDVQEAVPIINNIISGQFQNAEQWYGDYQTYPEQPYPGTEAYPAKIYHTWDPNWRGFIGTAFIVILEEFEHLLPAQIEEQMVESLHLNAIGDTYRVGGIDDDNLYPAYSNAAIMHAVVSSWVGRRTGDANLTAEGETWGRDIVELFDRNGTLSEFNGPTYAGVSLFALTLCAKYLPDEGAVLGANGGRMIRQIWDLTGELYNANLKNIAPPWDRSYGYDMNRYLSITALWIWSLVGLDQAPLYNKPWAVAHVDDVQIGPLIAILADYHKQFVDAKVMRSLTEFAEERFVHTAAFSPPYDISPRNITTWLSANLTIGAESFDEDVVGGPSINPQQFCPAVAQWLRKDGTVGFLSLWPETQALQVEVSERRLTLSYPDGNSTSTFVLHVSPNGLVGPKNVQSWSDIAGVRVRASGTINTTPSVSFCGINGGDCDPVNDFDLWNFTYSMPPGSIRTPYLVLDIELVQHRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9Q8L606_PASFU</name>
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        <name type="scientific">Passalora fulva</name>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Race5_Kim</strain>
        </source>
    </reference>
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        <text evidence="1 5">Belongs to the cyclin family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        </source>
    </evidence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L688</accession>
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
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    </reference>
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    <dbReference type="GeneID" id="71981499"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11583.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="158" mass="17653" checksum="F9A238EFC2E8CC55" modified="2023-09-13" version="1">MMVFLVMKWCLQSRCRDGSSPAVEVTRTAPRLLMRVTLILALDADGIAVSNELDLSHYVDTRLSKNDAYIECPSTCTKLEVRLRLPTAHPPYKDPCPTLRQQPVHLQQIKIRHLAFSSDVYHDSTAGGSRDEFGRVVSEYAGTVFKLRTPDGTAGIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8L6K1</accession>
    <name>A0A9Q8L6K1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_01084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8L6K1"/>
    <dbReference type="GeneID" id="71980962"/>
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    <dbReference type="OMA" id="RVIATYI"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="453" mass="51088" checksum="AF8522F5C67CCABE" modified="2023-09-13" version="1">MVYSLSYRRPSHVTSSRDSLNGDEKQKSIQESIASGNSCMSHGIPTALGFDRIIDGGTCPPVTVRDFMNYLKYIEHSAENLQFFLWYRDYQRRWKELPDSDRQLAPEWTKAQADVDANAISPARTKRVNPQIAEVLKGTDFADVTAKPVLDRADPFNTPPKSDSFDDKREITSDYGSSFGDDKTLLGNTTHAHRAVTEQAFEDAGMKWKPFTAQPFREEVSKIVSIYLAEGSPRELNLSAKERQSVLHALQNTTHPSAFQAIAPTVEYSLRRQAHPNFIRWTICNGNRPRVVFARGLGVAGILAGLLADLLITLSHAGRGWRVLPFVGWFIGIATLIAAWKGMCVVLHGLHHRHLRPWELFSDSVESAEDEKALSSEQSLYSSTRNSFEDEPWVPRHKKRHVIRKIFDREVWIKEPALRQIQDTIFLQALLGAFVTSCIVVGIFCAVPHGNLY</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        </source>
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            <begin position="19"/>
            <end position="128"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO11827.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="128" mass="12666" checksum="58B3B3B0E547EB2B" modified="2023-09-13" version="1">MRFSTTIAALVAIVAVNAAEAPAPPAYNQQSMTSATTTYTITRTLSRVVETVTATRNGTTATYESTSTVPATTLVSAAPTGYGNATLPGTAATASATFYPPPPSQGGAGKAEAAGIAVAIGIIGMLAL</sequence>
</entry>
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            <authorList>
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    </dbReference>
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    </dbReference>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="40754" checksum="87033C69129966F5" modified="2023-09-13" version="1">MPSILSQRDIGSSLAGVKDTFSGWDSCMSKAYCKWPVIIGIIIGSLIILSLVWCCARCICCGAECCCGCLACCNVCCPSPRGGRSGRNEGYQQAPPTPYHNQYHQPPPPMYTSGAAGYRSATVPQTATFDTPSKSANFNEDALPAMPSWDNATSRKVEQPYEDVEMEKFDQRGTSPNPGSQMLYQNPEPAYAGQQDNLLSRQETGRYSDGNSTHHVAASHSGGIGTMTAAAQPYHDYQQQRQLSPSPYESQSQNRGPASPSPYGSYDQSRGLTSPSAYSSQNEIRGPAAPSPYSPALRTPVSPHETTHTPHADSSANYFGGGQRGGGGYEASIPPSYHIAPPSDIVSPVSPQASYPGQQQYQAYGASNTGRQAAPGSWREV</sequence>
</entry>
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            </authorList>
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    </dbReference>
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            <dbReference type="EMBL" id="UJO12318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="228" mass="25642" checksum="21859744F5A0B9CC" modified="2023-09-13" version="1">MQRGAKVGRISLTDACTINAAHFEHGGVFRDIVQDIRIFEYFLEPASVTEPLIPHVQQLWDILSIIIQDATRLEQLVVAALDLQGGDWPTVLSRPCVQAFANSGLKSLRELRLERIMIPVDTLLLLVESCAATLESIKLKYCALVGDDPYRVLFRSLNAMSRLQVLTFCQLARRAQDDAKFHEDGYQGASFLLPGEATDRRTNETPNRKSTESTPFIELNIKHGVQYE</sequence>
</entry>
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    <dbReference type="GeneID" id="71982105"/>
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        </source>
    </evidence>
    <sequence length="2041" mass="221905" checksum="D3C0DEF595618E82" modified="2023-09-13" version="1">MAVSVATIRADELLKRDTQPPTYRSVERNCLKTRIGALVAFWESIHVAKCNVSNDARAVVPRQLYRPYGSALPRAGVLPTYEESVLDVPPDYTMTDALAKVHTSDESGIITSNKVEIGQDRKQENHELFGVLEKLDLQSSDHIRTHAGKKAKKAAKQAQMSKWADSDNEEKKEGEDGAAGDDNAGGGDAGGAGGDDPPGGNGGDDGDELNDSGKKGKKDKKKKKSIWDDLEDEEKKKEEEEANKAGEQPASGAADASPADDWGSFAAVGKKGKKGKKGQVEPEPVAEVVDVPAVEVAADDDWSGFTTGKKKKKGKKEPEPKPEPEPEPEPEPEPEPEPKPAVEAEDPWGSFATVGKKKSKKKGEPEPEPEPPAPEIPPPAETNDDDWGFGKKKKGKKGENEPVAPEPTKEDMNFDDINLNDDKTAPKLDIDFGLGKKTEPAAEKSSGFSFGGWGSGWGSGAAASWGFGSSQAEAPAEPKQEESTGWGFTSTSSKKSKDTKKSNAFDFSFDDTGGDALADTLDLGAPAAKEEPKAEEDLWGSTSAKDKKKKKKGAMVEPEPIIEAPPPPPVEPPAEEDPWASFSTKKDKKKKKGAVAEPEPIVEVPPPPPPAPEEPPAEDSWSSIGKKDKKKKKGASMWDQPEPEPEPEPIAIPEPEPVKEKEDEMPFGMSAKDKKKAKKAGKNAIVELPVEEPPPPPEPEPEPAPAMVDAFDGWGKTTKKDKKSKTKSTFDWSEEPAEPVIEVPPVVEPEPTTDWLGGGWADTSSKSKKKGKKGAMEEVLPPAPPPPPPPPEPVADAGGGDWFSGFGTTKKADKKSKKGKVDAWEPAAPAPPPIDDAFLMPEAVVEPKAEGVDDWANSWSTGTKKKATKKDKNKGVVEVSDPSPGASILLPESVQEKSAEDPWTTGKKTKKGAKKGSASDAPPVAPPPLALEDVPAHTADGMDLLDMSAPPADDSWGFATTTKKKGQVDKKGSKIVEAPKVEELTLSKTKSKDSKRSAFDDILDIVEEAEPEPAPESPKEEKKEDKSSSSGWGLFGSSSKSKPSKKETPKEQKEREKKEKKEREAAEAAEAEEAQRKADEDAFAAALGEDPNDILDLDDEPAPPSKKSSKDKDSKKKGTDKLGKVDSKSSKKSEPKEDPIAAIVNAPELDPDLDFDESKKTDGWGFWGSSLKSTKNATPATATKSKIGSDLWANQDAAYNGSTKMPDVSFGDNGLTSAMPPPKASASSKMKANAKTSSIQDRIKALQGDSTDAKPSKSKKGASAAPPEDFWPEPEPEPEPVFEVPVPAAVPEKKSKKSGSSKKDNKKDLSAAEPVIPHSESPVPGGFPVDDILDFDPEPEMVSPPPRKSSKDKKVSSKSTKESKSKKTEPVVVEAPPPPTNDDDLMGAGDDDLPTPPPEDETKDKSRSSKKERPKVVRDTGSSSWGFWGATPSKKPTKKDGATTPSNERPAGLSRSKSARKPSDKDPLEKSSKSSGSDKDGKRESKSRPSTSRGMSFSMFGMGGTPARSKSTRQSTKPSSRRHSTAVEDNGLMSPPPEDHEMSAKAAKVMGVSRSKSTREKSSRKVPDPYAIDSDDLVMVDAPEDSAKDMAEPKQRKKSSKSRREPSYMSGGLGGADDELMPDAVRHSDEAKVFSGPDDLAFVERPAPVRRTTSSAKKTAGLMGGILGAFSARPTPDRRQSKAYESEDGRRKRGSAYDDDHAKRLRREDRKVNRSRMPSDGNAYADPVPMTDVEDAEAKEARRRERRERRDREAADEEARAARRREKEDSRRVRAREEEDQREAERRRARRAEKEARRAEDDRLAREEEQAREERRERRREKERQRAEDEAAASSRPKTDRRRSYMDAPDDDEARRVRREERRLRRSVDQGTEKERPRPSRRRSDYPAADGVYDKRNGEHSPGVVPSPIAHAIKTGGDKTASWVHSVNEDRPPPPPIEGTIIDAPVHYAEDNAPDALDDTTAREYRNRRRREQGDYADEDSERRRRRRDVPSGSGGSSHGRNKSYGGPSNSLGYDDMGAKTWDGRPANNRRQSWFKKIAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LA45</accession>
    <name>A0A9Q8LA45_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras-related protein RABB1b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047757966.1">
        <property type="nucleotide sequence ID" value="XM_047902856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LA45"/>
    <dbReference type="GeneID" id="71983586"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03708"/>
    <dbReference type="OMA" id="ANGVMQY"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="274" mass="29571" checksum="EFBF183D6ED692CE" modified="2023-09-13" version="1">MAQPAQPYDFIAKICSLGDSGSGKSSLTIRLCEGRFVSHHDVTIGVEFGSRIVPVGPPASLEYNINNPAAAPSKPAPATKSPNDAKGKKGQPPPEPEQKHMKLSLWDTAGQETYKSITRSYFRGASGALLVFDITRRQTFASVTSWLHDLRQIAEDDIVVVLVGNKCDLASSSTLSDEPNRRQVTREEAEEWCKQNKVMQYVETSAKSGENVERAFLEVAERIYQNIEAGKYDLNDRRSGVKGPGAGGGKSSGVQLVKSDKNVAKKAGIAGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LAD5</accession>
    <name>A0A9Q8LAD5_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-1,3(4)-beta-glucanase</fullName>
            <ecNumber evidence="3">3.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_02939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;3)- or (1-&gt;4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.</text>
            <dbReference type="EC" id="3.2.1.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758087.1">
        <property type="nucleotide sequence ID" value="XM_047902087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LAD5"/>
    <dbReference type="GeneID" id="71982817"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02939"/>
    <dbReference type="OMA" id="TEAYWEF"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000114">
        <property type="entry name" value="Probable endo-1,3(4)-beta-glucanase NFIA_089530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF42">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02280)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="8">
        <location>
            <begin position="78"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UJO13721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="385" mass="41996" checksum="AF2FC7FCE0763E43" modified="2023-09-13" version="1">MYPNVTARDSEMMPPPSAPPPPYESIDGLDKMAEKSGSKWNPRNGSKLAILVAVIAAILVIVAGIVGAVLGTRANEYPDSSALSYTLADTYAGTDFFDDFDYFTGYDPTAGFVHYVPNTTATSEQYNLTYASPDTAILRVDTSETNADTGRYSVRITSKKQHNSGLFVFDIVNTPYGYATWPALWLSDPNNWPEHGEIDVVEAVNQADTGNQATLHTTSGCKMNVKRKQTGDTLYKSCANTTHDNAGCGVQGEQDTYGETFDANGGGIYAMEWRTAGIRVWFFPRSDVPSDIPTDVTNTSAPDPSTWGTPLADFPSTNCDISNHFKNQSIIANIDLCGTWAGSTAVYTDQDQCPGLCTDFVATNNTAFETAYWQWNSWRMYTAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBJ9</accession>
    <name>A0A9Q8LBJ9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LDB19 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047903029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBJ9"/>
    <dbReference type="GeneID" id="71983759"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03881"/>
    <dbReference type="OMA" id="MVVAEEW"/>
    <dbReference type="OrthoDB" id="3832628at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024391">
        <property type="entry name" value="LDB19_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13002">
        <property type="entry name" value="LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LDB19 N-terminal" evidence="2">
        <location>
            <begin position="137"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO14403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="579" mass="63607" checksum="6827BCC99DF1F2B2" modified="2023-09-13" version="1">MPGRILGLDFGRNSSTHNLDQSIPSATSNQTKSGERPLESRRPSMDKLVKRPGALLQLGKKHSSESKSKSKDRSGSRDKHASEHRVPLKPAPVKLNLHMESPPALMLDPPSQSSGVIVSGQLHITPNTSEVTLESCKLFLEKTTTTKRPIQDKCRDCITQIVDIAEWDFFKKPKTFKESAGKQSIPFSHRLPGNIPATTQGQLGSVEYSLHCRARTTSGEECEYRHELLITRAIRPGPDKTSVRIFPPTNLTLHVILPNIVHPIGEFPVQCRMTGITTKRDDTQTRWRLRKLTWRVEEHETMISPPCAEHVSNVGEGKAMKYENTRHIGMDELKQGWKTDFSEGQVDGEFMAHINPTAKPNCGMDTGSGFKIAHNLVLELVIAEEWAPNKKPENATYTGAARVLRTQFALNVTQRAGMGIGWDEEQPPMYDDVPASPPHYQNDHTSILNYEGEDLHNDIERLNLDGDETPNSSGGTITDLPESLPPSYSTTGGFSDPNFTMPSSSRAPPASSSAMASSSRYAPSPATTTPVAASSSRDATPTPSTISTPISSAAPSRSQSTVDEDELTALLDRSRQRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LBT7</accession>
    <name>A0A9Q8LBT7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Oxysterol-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CLAFUR5_03684</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO14532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047758898.1">
        <property type="nucleotide sequence ID" value="XM_047902832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LBT7"/>
    <dbReference type="GeneID" id="71983562"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03684"/>
    <dbReference type="OrthoDB" id="1854502at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120009">
        <property type="term" value="P:intermembrane lipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030011">
        <property type="term" value="P:maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13292">
        <property type="entry name" value="PH_Osh1p_Osh2p_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000281">
        <property type="entry name" value="Oxysterol binding protein (Osh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000061">
        <property type="entry name" value="Oxysterol binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="384"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="508"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="702"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="475"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="702"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UJO14532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1252" mass="139548" checksum="3A7CD373DF63AD22" modified="2023-09-13" version="1">MSSPGEGDKGSSSHRRNKSALSRAKSALQRRSSKGAGDVPTLKTLNTQSEEDENMPSPASGQNSNADSLYLSPTRTSVHSHRPHLSTTMSNTHGIPAANASSPTKDSPISPSSAATQGASIEQSVRLFKVFEALRNGDTAAIAKATRTDGDGGRLEGTTILHLAIQCAEIPVIEYVLSQHDADVNAKDKDGNTPLMVASSLGRAPVVKLLLDQKAINDAAVNYQGKTALDLARNPEIFQLLQLARSMLIDNSVRHIHQLVSAGNYDVLEQTLSDSRFKSVIDINGPELATESETAATGGSLLHEAARKKDLRLAQLLLLNGADPFRRDRKGKLPQDVTKDDRTRAILKKSPAAAAAQRQIQERTILGENTQGLQASEGPGSKESREMKGYLKKWTNYTSGYKLRWFVLEDGVLSYYKHQDDAGSACRGAINMRIARLQMDPKDKLHFELHGKSSVRYDLKANHQVEAKRWFWALNNAIQWAKDEAKEEQKREQQEASVRHEQLEKLRTREADIAHSSDSLKPATTLGVDTPGGSTHAGTTLADGRSGYMYAPSHTDDDASQIGRFVTRTNTQTNVDGDVDDDDGYGDDASSHEMRPANKDAFSITAQSAKLQLDLLEQVSAALQSERTKNPDMAIGHQTVDRALSSYEMAVGNLKGLLMDLLRISRDHESYWQYRLEREQNIRRLWEDSMAKVAREQEDLENRIGESEDKRRRTKRALKEALDGQTSAAPTPQPTAEPPSSKGLLEIPVDAKPMKRRATIAELTNNEISDDESEEEEEFFDAVDAGEVEVLETMPPRVKSPEVEVTPVMDIAKDGATDGGIDRSVEAERKEREQVISESYKGYEDGLRHKLKIDADNRPKVSLWAVLKSMIGKDMTKMTLPVTFNEPTSLLYRAVEDMEYAQLLNVAADRPDPTERLIYVAGFAASIYASTIGRVAKPFNPLLGESYELVRPDLGYRYLIEQVSHHPPVGAAYAESPKWTYYGESAVRSKFYGKSFEFNPLGTWFLHIRPVDGGPEELFTWKKVTSSVVGILTGNPVVDNYGPMEVKNWTTGEVCYLDFKPKGWKASSAFQVAGKVVDAKGNTKWSVGGRWNDKIYARHTPGFEETIEVPADGKSQSSNQAIKVWECNHRPPPGEIPFNLTPFVVTLNALPDRLRPLLAPTDTRLRPDQRAMEEAEYDLAATEKTRVEEAQRARRRVREAKGEEFRPRWFAKAKHPVTGEEFWQFNHEYWKIREEVAAGKRRWEDERLEEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LC05</accession>
    <name>A0A9Q8LC05_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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</entry>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="84" mass="9995" checksum="614BCB6E5A740F3E" modified="2023-09-13" version="1">MGSRAINMPHPNGDPTLEEKLALFTKKRDQYRKEEAGIKERREKREALKQKEAEEAKDRKARQKERRNEKKSSKEWKDGKGWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LES2</accession>
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        <property type="entry name" value="Marvel"/>
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        <property type="entry name" value="NCE102-like"/>
    </dbReference>
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        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF1">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO15894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="166" mass="17956" checksum="D43B5E2D81E3069D" modified="2023-09-13" version="1">MKIVNLALRALQFFMALLIMAIIGNAIAMGADSPVNNYTMFCAAFAMLCLFFLLPATFKEEWSVMPFLPFVLDLLLVLFWFCGAVALAAELGVHSCNNDDYVSSNRVIRGARNQHSACREAQASCAFLWFGWACFVGSAAITGMAMRGGGAPRGGIRRGGPVMSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LES9</accession>
    <name>A0A9Q8LES9_PASFU</name>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_04763</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760483.1">
        <property type="nucleotide sequence ID" value="XM_047903911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LES9"/>
    <dbReference type="GeneID" id="71984641"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04763"/>
    <dbReference type="OMA" id="SITDIWF"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
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        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
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        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
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        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
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        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="427"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO16117.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="54686" checksum="E03E53407A34201B" modified="2023-09-13" version="1">MDDEKQFPPGTVRLIDVHGKLLTKHASSAAEQDIVLLPRPSDDPEDPLNWSFKRKMLATSCVLMYTLMVALPSGSVSSVVKPIEKATGLTLNTLNTGTGVMFLAHGWACVFGQPLALQYGKRPAYLVSMATSIIIMACAPLCATRGTYLANKVLQGFFGAPVEALCEISITDIWFAHERPKYLAWYGLSLSITGKLAPMLAGFINDGQDWRWVLWWTAIWIGIAFIYCFFLMEETNYDRVHSPHNHASVEATDAPSGLTTPGDEKDLKHITTNPTPDIEPGHLTTYTRKTYLSKLYLLDKPRPNRMLVIFLGPFKGFTYPVIVYAGLMYGANALVWSGVQNATTGTVYTTYYGFSTTAIAAAYSGGVVGCLIGAYYCGKMGRILTLRLARKRGGISEPEDTLYMFIASMILVPFSMLLYGLGVTYRIHWFALVFSQASLAISNSLCVAGAISYAISSYHALSGDMLTTLILIRNTLSFAVNYGHVSPHKGFLRGKMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LEU3</accession>
    <name>A0A9Q8LEU3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_05376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760465.1">
        <property type="nucleotide sequence ID" value="XM_047904524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LEU3"/>
    <dbReference type="GeneID" id="71985254"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05376"/>
    <dbReference type="OrthoDB" id="3836365at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="174" mass="19760" checksum="78EBDEAFB4E2E73D" modified="2023-09-13" version="1">MGPEEAAQPAQYIFGRENREFVVNAQATADRIFSRRSITKSNRNQQIKAEIARRQAQGVPATIHTARPSKRRRGPDDQIDDDERDRVLRPKRRAVAQNNQVSAERRAIRKQARPRGDPKVRCWDWMLHNGDMHHARNGSAFDTYEKINEEVSTPLALGDGIKAVGIGTVRLEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LFG5</accession>
    <name>A0A9Q8LFG5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047760871.1">
        <property type="nucleotide sequence ID" value="XM_047903534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8LFG5"/>
    <dbReference type="GeneID" id="71984264"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04386"/>
    <dbReference type="OMA" id="TAFFWQD"/>
    <dbReference type="OrthoDB" id="420422at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19490">
        <property type="entry name" value="XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030547">
        <property type="entry name" value="XRCC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO16505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="359" mass="39728" checksum="01D2ECE78195E3A5" modified="2023-09-13" version="1">MSAEDLGRRLLAEVEEIGLDELLNDLRLRDDGPISRFDLPPLDSILATIDQARASNGKTAPTTSPIVELMSLRPDVGTSNILYHLTALAVLPRNLGGRQSCVVIIGADNTFSIPRLAQQIKTLAFTNRSSDATTNTINDAIHTSLKHIHIFHPQSLPSAIATLNFLQSYLFNATRHSSFDRPVAFIALDSASSFYWQARSDADDAALLANTSETSQRTPQGYPHLTAALKNASRILHAPIIYTTRYTGSGPPKSNNSNTGFELGPRSFRPNLPQPWGTLPILRLVVRRMEVRKLPVGITVEQAQREDEARRKVVEKGKFEVFVNEWGVDEAVLRKLREKELDGFEVYVNKVGLQLAAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LGJ3</accession>
    <name>A0A9Q8LGJ3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_04591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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</entry>
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                <person name="Stergiopoulos I."/>
            </authorList>
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            <authorList>
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            <end position="170"/>
        </location>
    </feature>
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        <location>
            <begin position="146"/>
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        </source>
    </evidence>
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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            <dbReference type="EMBL" id="UJO17930.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="219" mass="24664" checksum="18F1B498FF830224" modified="2023-09-13" version="1">MPRLTITILARNEPLRRYYVEHIWKLAGFIGGPIATYITDDKGEFEFDSSTHEADIRMLGQKSVTRIVEGGGALFTADLWVDRRVEAGTTIRLDNRQEKVKHFEILNKTIELYDAVHRNFAPFSALSDTAFPLGKKATLQKTKDQVTRIETVYPDNLGQELAFVEPKSVRTGYPLIHLKGPGQGAEDGSKPLSRELAHALHSAQLDDDARDKVEVDYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8LIM8</accession>
    <name>A0A9Q8LIM8_PASFU</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
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        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="214" mass="23452" checksum="CE16C810D7F47C7A" modified="2023-09-13" version="1">MTTAMATTATQTLDLLEARLQRLSFLLSGDGNGDDEHPSTSTSTSTSTTPAKVRLAGIERNLKSLAARSPAVADVLQLHRAHPDLFNASSTSTPPSTLPTASLAQLVLAHEQLYKTTNSQLTTANDSKNIPDPSSLTKLIGLTSRIDAAEAKQVEQAREFAELRGRSAKIVEKWYEEGVLDMGERWADWEERLRDAEILVRRREAAKRREEAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P2J9</accession>
    <name>A0A9Q8P2J9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Agmatinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CLAFUR5_00805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the arginase family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO10993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047899953.1"/>
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    <dbReference type="GeneID" id="71980683"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF28">
        <property type="entry name" value="HYPOTHETICAL ARGINASE FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UJO10993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="251" mass="26850" checksum="67FD38C04BDCD902" modified="2023-09-13" version="1">MAGPCVGKNAFQQGLKVVDCGDAPLTVLSTRARYPAHHTVTLGGDHTTTLPALRSTYNHWGPVSVIHFDSHLDTWDPDVLGAGLSHYAGVNHGTFLHIAHEEGLIKNSSIHAGIRAPVSNKKYDFANDKACGFHILKARHLDRIGTAGIIKTLKDRVAGSKVYISVDIDVLDPAYAPATGTAEVGGWTTRELLTILDGLSGIEVVGADFVEVAPIYDSPGETTVLAAAEVVHSLIQLMADKPMESMRKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755494.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P2P5"/>
    <dbReference type="GeneID" id="71982094"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_02216"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="110" mass="11920" checksum="7C846681694A8B4E" modified="2023-09-13" version="1">MDANGRAFLQADALSRVNALAALLSAITTEPWIIHVPETLLRLTSPQARFVVKYDQLSTKDIDVYLDRCPYGTYGTSSGRRCLTTSAAAQPTNPEGAVIKEPVMQTHGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P314</accession>
    <name>A0A9Q8P314_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_02293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    </organism>
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                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">Race5_Kim</strain>
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    <dbReference type="GeneID" id="71982171"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO11458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16561" checksum="495FAB440FC36041" modified="2023-09-13" version="1">MVSVTCRRASVHAPTSMFIASSIATISITRTTSHTSVACSIPVPSTSPRSIISIWPSLTSARSRHTRRTAPQPQAAMVLGRLAHYTFDAVLVSAFLAGVKRSTGLTPSLKPDTFSESPSIKKWIENYLWVGETIMDQSVAVMSSSGYFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P316</accession>
    <name>A0A9Q8P316_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_00556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755705.1">
        <property type="nucleotide sequence ID" value="XM_047899704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P316"/>
    <dbReference type="GeneID" id="71980434"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_00556"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO11339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="296" mass="32735" checksum="25A93A15D21EF4BD" modified="2023-09-13" version="1">MHQESDVVEMYKSLREGRLNAGTSTIVSRKQRAPTSHLLIFTFTTMLFKTFFALAFASLVLAQNDGDEEARRPDPTTTRSSSCRATTSTRRNNGTPTLYVTRCATTTATITRPRTTVTTTSVRTIRVTTTTRRPATTTTRTVTSIISRPVSTNTFTVTSTSTTTSTATPSASAFPGVYAVYGFEQDNCQASRRNDFQDANGELVLLLAPELIEDQETTSTCVRFSDIRVNSLLFQDYPDGLQLPDRCRLYAYQGVNCNTGSGQRTFDISLEAQAENTCRDNDITTVRSIRIVCRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P320</accession>
    <name>A0A9Q8P320_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CLAFUR5_01257</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO11535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047755901.1">
        <property type="nucleotide sequence ID" value="XM_047900405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P320"/>
    <dbReference type="GeneID" id="71981135"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_01257"/>
    <dbReference type="OrthoDB" id="10261039at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.330">
        <property type="entry name" value="Nucleotidyltransferases domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="44"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="197"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="338"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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            <dbReference type="EMBL" id="UJO11535.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="670" mass="73623" checksum="54629F0CC0CA7D85" modified="2023-09-13" version="1">MLRLAVARSNACLEQGARQPIRRQWQWQPQPYRQPLSRAFVDARSPDKTVLPGSQSGTVAGVPQAPVLPPATEKPAATDIPPIGTPLEPPSPAQVKSAPPAPSTNTGNLPPIGTGTAKTGPSSAPPPPPKKKGRFRRFLTTLLILSALGYGGGVYYSLVNDNFHDFFTEYVPFGEDAVAYFEDREFRKRFPQREFAGRNWPQTRGENKITIGRQSGVNPRVAESETDNVGSDLAQRGRHTSALDDNKANPAEQKKEQKPAQPAKKGDKPAAKQNDKTAAPSTPAAPHPTSTLPAASLVDNLAVSEGQEHAVQEVVKLVNNIITAVNASPEAPKYASTISSAKQDLDKVISEIKTMREQIAKDADSKIQSAHTDFDNAAKELVRRLEGEMREQETRWREEYEQEREKLSTSYQQRLSAEVDATKKVLEQKNKNALLEQEIALQKKFMDDVRSKVEEERNGRLSKIDELSSNVQELEKLSSQWNEVIDATLQTQHLQVALEAVRAKLQVSDHPTPFINELVALKEVSKNNDVVSAAIASINPAAYQRGVPSGAALIDRFRRVATEVRKASLLPEDAGVASHAASAVLSRFMFQKKSDRGLPEGEDVEATLARTEVLLEEGDLDAAAREMNSFKGWAGVLSRDWVSECRRVLEVRQAVDVMSTEARLQSLLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3K4</accession>
    <name>A0A9Q8P3K4_PASFU</name>
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        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="4" type="ORF">CLAFUR5_00879</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047900027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3K4"/>
    <dbReference type="GeneID" id="71980757"/>
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    <dbReference type="OrthoDB" id="5062908at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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        <location>
            <begin position="458"/>
            <end position="484"/>
        </location>
    </feature>
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        <location>
            <begin position="494"/>
            <end position="524"/>
        </location>
    </feature>
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        <location>
            <begin position="269"/>
            <end position="340"/>
        </location>
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        <location>
            <begin position="380"/>
            <end position="410"/>
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        <location>
            <begin position="533"/>
            <end position="573"/>
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    </feature>
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        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
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            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO12028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="650" mass="71350" checksum="08545BD57B8BD7C2" modified="2023-09-13" version="1">MTYRTSEEHLVPSEEYSPYSQPGSVLFSHPCEVDNWCHSIPFAEGYPLTPPDTASECALSDCPDMSAQAWSQASLPEESWRTAPAPGNSTMMQSTGNDWHHGAPITTQELQALDASSWLNVSQGPVDMGLSPVLSQESQNTHSLGSISEPEIPLLPPGLDLSFISEPSWDPSAPVIYSSAGMNQEGLSYATVSPQHVSIEGPLSQGYGLPQSAVSDSHSPMDYFQGPHAPYPRRTASDPSVFQGRPILPRSDGVPASARVQYTAIESRYPHVGAPETARVSNTDGRSKAPMEPAQRQGPPSRHYRASPLSHGSLSPRPDTVPPTRMSGPYASHPSDDFSNFIRYDQEDKTTPVNNSYLGAYGSVAGKLPSSVGGEAKPMIAKSTQDGSAAFRSTSSATSSQVGDGDEGRYRNHPLYSEGPKADGLYHCPFTTDPSCGHKPTKLKCNYDKFIDSHLKPFRCKIESCSKQEFSSTACLLRHEREAHGMHGHGDRPHLCFYPGCERGIPGNGFPRRYNLFDHMKRVHDHKDEAPALIQESQGSRKAASRKRKSPGSLSEEPAAQRRKTQVMQQPTPPPMVMSVPGYAPQAPVYHADARSHNRQRVIYSQWANQRELLEFQMNSVRSPDDEANLQRLSQNIEELRRLSHQARQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P3Q4</accession>
    <name>A0A9Q8P3Q4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">CLAFUR5_00588</name>
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    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090163">
        <property type="protein sequence ID" value="UJO12270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047756636.1">
        <property type="nucleotide sequence ID" value="XM_047899736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P3Q4"/>
    <dbReference type="GeneID" id="71980466"/>
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    <dbReference type="OMA" id="TMSPTNT"/>
    <dbReference type="OrthoDB" id="3650014at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040183360" evidence="3">
        <location>
            <begin position="20"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="208"/>
            <end position="306"/>
        </location>
    </feature>
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        <location>
            <begin position="334"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="276"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="301"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO12270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="480" mass="50893" checksum="9BAF2B23583DBFE3" modified="2023-09-13" version="1">MATLSCLLMLLQIVQYSLTSTSAQITPRPNEYPDAALGEIEQLWKRGTNVCDDQGIFHCPTGTCYEYHGSIGCCSVSSCAPRTTCIEHIETLITEPCDRNTGGCLYCNNPAAPHCRTQTNPLNSQYNHYCDTIGGTITVTTGTFAKPTTVATSTSISTKTMAAMETASAAASPGHSLSYGAIVGTACGVSAAVLLVAAALWYIRSRKRGQHEEEQEKHRGATDEIPASESRDGNEQAPNKDQATRQAAAIMAPTSCGDHDTAKQSTDNLGSPTSTLAYMPKDGTRYTVTNPDLNPISPTDSSIRDFKPSHTSAVEAPSDRPVMAKRPFIPVSESNITAPSRTNSASQFPSPIAAHTPYTPSQYHPSAPNSIAKPFLQPPSLPQDYSTATFASDATRVPAGLYTPSNYQPGAPGSVARTAPPNLPQEYSAATLPSDNPDGSPIYRGLRSSSSSAFPPYAYLSPEDALAGGWTNDSPPHGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P4U0</accession>
    <name>A0A9Q8P4U0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_03701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090164">
        <property type="protein sequence ID" value="UJO13318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047902849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P4U0"/>
    <dbReference type="GeneID" id="71983579"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03701"/>
    <dbReference type="OMA" id="NDMDRRA"/>
    <dbReference type="OrthoDB" id="10356343at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040122453" evidence="2">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO13318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="136" mass="14620" checksum="E81792982F62E7BA" modified="2023-09-13" version="1">MEQTTIALLILLYATQIMASESATVNTFSATLVKTGPAPTGPNDHMISHLSQGARAGISTSAIFGAILLFGIAFFVWKRMKKARMERASQERYLELQTGGPHQAAFSQASSLKPAGSVPGLHLPLAHIQRSKELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P564</accession>
    <name>A0A9Q8P564_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_03855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
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                <person name="Stergiopoulos I."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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</entry>
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            <authorList>
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                <person name="Stergiopoulos I."/>
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    </evidence>
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    </evidence>
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        </location>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14385.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P680</accession>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2" key="2">
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                <person name="Stergiopoulos I."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">Race5_Kim</strain>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO14699.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
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</entry>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
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        </source>
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        </location>
    </feature>
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            <end position="34"/>
        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO15690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="486" mass="54685" checksum="33E332E2CDBA4B7A" modified="2023-09-13" version="1">MAPKRKRLAAADSPRKRGKGGNSNTSKKTNPKSTLFTLPAELRNRIYELALVTSDQDTRIRVRPQLKFPGLLSTCRQARAEAHKIYWFQNKFNQTVRDCNGSLHIKFERLLFDNMGEAAFQIDFTLIVAGRKSWANLLEWCRQLHADENGSSGLRMDPNWNAQETVVAAAHRIAFTHGESTWECCLEALGALRAVAGLSSKKWLDDYRENQLYWVSVRRIRLQGVFAGPVDSVNGHEAHVIHVPLSRPHKVLEQNLTLVAHAEVCTLSPTESSPLPLPLPPPREQMALKRKRITNSEGAIQRAKHADGVESQKDEQAPTLLTLPAELRNRIYELALLRPGLISITSSLKAPGLLATCRQIREEASKIYYLQNKFEMDIRDCDGTLGNAYLQLLSRYASHDTQAHLNFSFMGKRNWTNLMVWCKDLYERPGSLCIPLQDGQCPLVAVVAAAHSITLSHTNSSWQDCLEALKALRHAVGTLDKAWMKD</sequence>
</entry>
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    <accession>A0A9Q8P7V5</accession>
    <name>A0A9Q8P7V5_PASFU</name>
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        <name type="common">Tomato leaf mold</name>
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        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71985261"/>
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    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
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            <begin position="141"/>
            <end position="161"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="551"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="744"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="784"/>
            <end position="805"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO16514.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="844" mass="94466" checksum="7AFC6F8B391ABBE5" modified="2023-09-13" version="1">MTRKNVRVRWNRGEGARSETTGTLDTSSCTNTELTETFTREDPVISKVAAEFAGAIRNVYAEERRGISEMEAHRRLIAFRDMHRYDPNLPDAAFDAINDATQRHDHKSEAVLIRELVEDSPYPEVRAVVRNDDIDVPVSTIRAWTIGLFMTTVVSIFNALFTLRYPNIWIPTNVVQLLAYPLGAGWAALMPCRDISLFGIKAHLNPGPFNVKEHVLIVVMANAAVGGGAGYFVDTVVSIQKFYKISGFGWGFNILFALSTQCAGFGLAGLVRRWVVEPAPMIWPSALASVAIINALHEHIGSEPEYKNDWSIARYKWLLYVIAAMFIWSWLPNFIFPALSYFAWVTWIKPNSVLVNQLFGQTTGISLGFPFTGFTLDWAQINSCYDSPLIAPWHASANILVGVIAITWVIVPAFHYTNTWYANYLPISQNGITDNTGSPYNISRILTPEHVVDPVEYEKYSPLFLSTQFAVTYGVSFAAVSALASHTILYHSKEIWERWRSSSSERDDIHMKIVRRYKIVPTWWYVVLLAITTAFAFAAACAFPTGMTASLVLLSLVIASALTIPAGVIQATTSTPLGLNVFTELIIGYIQPGHPIAMMLFKTFGYITMTQALSFCQDLKLGQYMHVPQRSLFTAQLIATAWSCFCQLGIVQWALGAISNICTAEAAAHFTCNNIMTFYNASVIWGAIGPKHLFSGTAIYKDLNWFWLLGFVLPIIIYGVGRAFPKVSMLRRVNIPLVFTAVKYIPPYNAMNVLAYCLVSFIFQKHIYTRARGWWMEYNYVTSAGMDIGLAICAIMMFFCVQLPGVSMAPWWGTKVIETGDYNGTARRDTLSRGETFGPAVWKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P824</accession>
    <name>A0A9Q8P824_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_04610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761017.1">
        <property type="nucleotide sequence ID" value="XM_047903758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P824"/>
    <dbReference type="GeneID" id="71984488"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_04610"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO16651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="459" mass="51720" checksum="EED2842127C69A8B" modified="2023-09-13" version="1">MRQEAVDIPAKTHGESTATRDSQDSQQDSPGVAEDRDDFSDGIDRLGSMDFHEMNRVRHHEMRSYQALEDSVAMGLMDASELERYDDDDPTATERVLECIPADTKPLSRTELLGNGIDNSVRISVRDFFAAQASASLVHGRTVGMSPVSGLTALHFRQMQDLAMGREMSGDDGSRMATTKVCKIVTKIDDTAYKTEPKRLFYNDTEITLSTTDKHKYRGDGTAVIAATTRANTVLAPQSLLADKTNQPAKGPPNFSLMGQPDIYNATNLEKHMKQPLKEYAKENLLLQQELIAMTPGGWRACDAKTGEVIDDDHKLFKEACDIIKKYIEGTNDKWYHNEVLRAQQQALPRTLLRNDPLKWVQKRLSSRPEAKRKPRKGTKKQQIPTAEPQRRFCLVHKSQFHSDTYFEGFGDPPSVDEKGDESSEPQKHDSMSPVEDRELPIVEWLHSLAFSLERVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P863</accession>
    <name>A0A9Q8P863_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-coumarate--CoA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_05156</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO16860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761226.1">
        <property type="nucleotide sequence ID" value="XM_047904304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P863"/>
    <dbReference type="GeneID" id="71985034"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_05156"/>
    <dbReference type="OMA" id="THASGMQ"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="454"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO16860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="554" mass="60843" checksum="ABE2C79DE2FC6460" modified="2023-09-13" version="1">MPHKSPYPDVDIPDVDIWSLLFDRQKRPYRHDKLLLQEVNSARKYSYKNLRQASIACGQGLRDAWKWQKGEVLAIYSPNDVDYAAVSLGCHWAGGVVTTVSPACTTDELVGQLRDSGARGIVTHQSSIDKAKAAAREVGIPEDRIALMGPEAAGAGAKHFTALTGNSHRSTDERRPFAINPRDDLAFLVFSSGTTGKPKGVMLSHRNIVSNISQGAVSSVGNLGCGDGTTGSGDKVMAFLPFYHIYGLTVLLHFGIWQGLESFVMPQFDIRQFCETVQRHKITYANIVPRVAVALAKVPIVEKYDLSSIRMLNSAAAPLSKELVELVHKRLSIPIKQAFGLSETSPGLTQQDWNDWDRGIGSVGHLLPNVEGKVVDMEKGTELDVDGVGELCFRGPNIFKGYLNNIAATKNSLTADGWYKSGDIGYVDRDGRFFITDRIKELIKYNGFQVAPAELEGLLLKHPKVKDAAVIGVFSQERQTELPRAYLVLDEGAARSKETAEEIAQWLGARVANYKRLRGGVRFIDAIPASAAGKLLRRELKVMAQAEEKTRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8P8N2</accession>
    <name>A0A9Q8P8N2_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_03945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090166">
        <property type="protein sequence ID" value="UJO17071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047761437.1">
        <property type="nucleotide sequence ID" value="XM_047903093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8P8N2"/>
    <dbReference type="GeneID" id="71983823"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_03945"/>
    <dbReference type="OrthoDB" id="4605274at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053228">
        <property type="entry name" value="Stereospecific_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574:SF1">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040284722" evidence="1">
        <location>
            <begin position="24"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO17071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="444" mass="46762" checksum="B8D9C5EB858A2686" modified="2023-09-13" version="1">MLIGNMTMLKALLPLPLLTLATAHPHAALEQRDLVGNMVSHLGADGKNLAKVASALVEAIEATVPTATITSPAQASSVLSGIFATATNFLDTAPALIAAGFDPDDIQDIVEGYSPAQNSVNNTNPAPPKNIYPASPADAPYSLSESTLRSGIYIPPTFTYGKKPPVILFPGTGVAGGMTWAFTYGDQLAKEPNADPVWVNIPKFSLDDAQLTAEYAAYAMSYIGAITNRNTTIITFSQGSLNVQWALKYWPSTRSVITDFIALSPDYRGTVKAGLICPQSSPLGCTPSILQQKTMSKFVKTLLANGGGSAYVRTTNVRSATDQIVQPQAGPHPSGVLADARNVGVANYLVQDVCPASPAGTLVTHAGIIYNSLAFDLVLDVLNNGGPGQASRLNLPQTCSRVVAQGDSLNDLVAVESTFVVFLTNFAAYMPRTFVEPPIKAYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PAV6</accession>
    <name>A0A9Q8PAV6_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial import receptor subunit tom7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_07401</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom7 family.</text>
    </comment>
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        <property type="protein sequence ID" value="UJO19078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047906549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PAV6"/>
    <dbReference type="GeneID" id="71987279"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07401"/>
    <dbReference type="OMA" id="FILYLGW"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012621">
        <property type="entry name" value="Tom7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34944">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34944:SF2">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08038">
        <property type="entry name" value="Tom7"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
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    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO19078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="56" mass="6535" checksum="47F9A13E496E7694" modified="2023-09-13" version="1">MAWMQLSEESKERIARVIDISRVAIHYGYLPLIIYLGYTRSNPRPSLIRLFSPLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBB1</accession>
    <name>A0A9Q8PBB1_PASFU</name>
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        <submittedName>
            <fullName evidence="2">Pre-mRNA cleavage factor Im subunit 2</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CLAFUR5_07231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
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        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
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                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763704.1">
        <property type="nucleotide sequence ID" value="XM_047906379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBB1"/>
    <dbReference type="GeneID" id="71987109"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_07231"/>
    <dbReference type="OrthoDB" id="277288at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
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        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NUDIX_Cfim25_Nudt21"/>
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    </dbReference>
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        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO19338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="295" mass="33911" checksum="E1A8C7D2ABA3EA10" modified="2023-09-13" version="1">MSPGACCCYMYQWFLKHCSIMSTVTPAHQLSSVPAKDILPFQSRQQPAVRLYPLSNYTFGTKETQPEEDASVKDRLKRLEEYYEKHGMRRSCEAILVCHEHNHPHVLMLQIANAFFKLPGDYIPHDVDEIEGFKTRLNDRLAPTGSLAEKDDHDWNVFDTLAQWYRPNFETFMYPFLPPHVTRPKECKKLYFIQLPTEKVLSVPKNMKLLAVPLFELYDNSQRYGPQLSAIPHYLSRYRWEFVDEDGKIVSWTPGGEVDERVKTKILAGGENGHAESGADPDVKMETKGEEPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBF9</accession>
    <name>A0A9Q8PBF9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit cut9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CLAFUR5_06973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090168">
        <property type="protein sequence ID" value="UJO19350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047763716.1">
        <property type="nucleotide sequence ID" value="XM_047906121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PBF9"/>
    <dbReference type="GeneID" id="71986851"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_06973"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
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        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="481"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="590"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="UJO19350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="618" mass="69147" checksum="03AD022D8E911C1A" modified="2023-09-13" version="1">MNMEGMHNFLRSWRQDALDRQQYDTAIFVGDKLLALTKSDDDTLALAHTHFAAGNYTRALAYASRSDLIQRKASARYLAGHCYVKQNRHDDALALLGDKNPVHLITTADGARRKLQHISNGLSSKQHGKSRMPNRTDRVDRSEERDREDASNLKYEAGMCYLRGLCFAKQNAFDRAKECYKDAVRIDVQCFEAFSQLVRNALMTPEEEWQFLDSLNFESIPPPAGETAAVPEAADFTKSLYTMRLNKYTRREEFDAAIETLENYKLDDNPDILLAKAEKLFNASRLRSAVELTNEILGADPYNFACIPLHLSLLHKLNEVNALFALSHDLADTHPHEPCTWLAVGTYYLASNRIPEARSFFSKASMMDPHFGPAWIGFAHTFAEEGESDQAIAAYSTAARLFQGSHLPQLFLGMQEIALGNLSIAREYLTAAYNLCKTDPLLINELGLVSYMDDDLEPAIRQFTLALSIVDENEAPASQYTVIRLNLAHAYRRSGQYAEALEEFDEVIRLGMQDAGVFTSKGLTLLDLEQPFDATVALHSALAISPQDPIATELLNKALEQLEKVSVLAGADEDELDARLRNNLVNIHQTRSTGRRQGRRVQQSDGMDLDGAGDDDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PBG5</accession>
    <name>A0A9Q8PBG5_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_07644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
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    <dbReference type="GeneID" id="71990553"/>
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        <property type="component" value="Chromosome 7"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:lipid metabolic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="AB_hydrolase_lip/est"/>
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        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="113"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="332" mass="35599" checksum="D4B22992BF23611B" modified="2023-09-13" version="1">MLELGACDSNASRRCTSSSARFRPHRSGSLALHVSLFEVGPGRATSPTPSDFALVQLSHDLYNNLATYAGFTQLSSGSCSTLPNGATLITAFDIPATDTQAVLWKFPAKKQLVVSFPGTASGQDWLTDLVFFPVPYISANIDCPLCSVHVGFLAAWNSISASLMEELRKALEGNEGYTTIITGHSLGGAIAQLAFASLKEEEWRVEAAYTYGQPRVGNLLFSHYIDSISKASDADPGNFYRVTHANGKLFTVKDREKGPDDLIDGVPSLPPALLGFVHSRTEYWESAESPAANSTFRCDGKENIGCNAGQFSLGINGAHLSYGGFDLQCVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD50</accession>
    <name>A0A9Q8PD50_PASFU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">CLAFUR5_10700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="71990578"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10700"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO20222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="291" mass="32424" checksum="352F66138191AB2F" modified="2023-09-13" version="1">MAYIATTKCPDVDENTTNYCDAYFKDMIHTANLCGDTIFTPKLLSLSLGHGALTLNSNGYVLPSLNNYIKIPHRQFSEVSSRLGHLELVSTDISVFQPNAETLWRRIFKDMINLHTLVIQCYPSELNDFQTLVDIFLRSPDLPSLRSLTIVGPKPGPIPIDSKALLNFLSYHQDLEMLGLLNVLPMEEDGAGGLARNVLSTVHELRQHAGLRGVGFIVAPYEGGFHSGKECQKPEQYGVVNKCFCRECVSEALQWLNKGMDVPIEAGGYQYADLVWTGPMPDLKGEEEEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PD56</accession>
    <name>A0A9Q8PD56_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_09875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090169">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PD56"/>
    <dbReference type="GeneID" id="71989753"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_09875"/>
    <dbReference type="OMA" id="VMSPLVW"/>
    <dbReference type="OrthoDB" id="3897607at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39614:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="3">
        <location>
            <begin position="40"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO20278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="376" mass="41795" checksum="E22C611CC927EA94" modified="2023-09-13" version="1">MAIPDTLTPPLAVINQDDQRGVLWTVGVICFAFIYLTFAVRLFVRWRRFQIDDYAILVACVLILAEVAVSFAAVAMGLGTTASTLQSADRIRTLWQLFMASEAFYVLATWTAKAAVLLTVRGLLSRDARMRIVFHLTLAVVAALGLASLLAVIVQCGSGSLMPNVDGHCHQQPRWIAVAIADTVTEIWGFSLFCKIVWSLQMKWNYKWTSAAILGLRLFCIAFAGVHAHYVSAFEQDPNPAVRIIQPLAWQQVGLTWSLLSAMVVALRPFLRDFHTGFGMDLATRNDSTYGHGSNKFSPKGYRLKELSGGRHTQSRSGHRDVSNEPPPKGEQFRADDIQYSAAIYHGARKPSEGSTQSHEPIIRREVEYTVTYETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PDE8</accession>
    <name>A0A9Q8PDE8_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CLAFUR5_10444</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090169">
        <property type="protein sequence ID" value="UJO20372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047764738.1">
        <property type="nucleotide sequence ID" value="XM_047909592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PDE8"/>
    <dbReference type="GeneID" id="71990322"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10444"/>
    <dbReference type="OMA" id="IVEPWIA"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="6">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="98"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UJO20372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="258" mass="30111" checksum="A593A2E05AC29212" modified="2023-09-13" version="1">MAPGKKAGTVKMSVPTQDQILVPETLLKKRKSQEKERAEKAEQREQRKKESKQKREQIFKRAESYVKEYRDLEREKIRLNRVAKSEGSYYVPAEPKLAFVVRIKGINKIDPKKRKTLQLLRLLQINNGVFIRLTKATSEMLKIVEPFVAYGYPNLKSVRELVYKRGYAKTSQKQRIPLTDNGIIEEHLGQYGIVCMEDLIHEIYTVGPNFKQASNFLWPFKLSNPTGGFHKRKFLHFIEGGDLGNREEYINQLIRQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PF04</accession>
    <name>A0A9Q8PF04_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CLAFUR5_10903</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="CP090170">
        <property type="protein sequence ID" value="UJO21253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047765619.1">
        <property type="nucleotide sequence ID" value="XM_047910051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PF04"/>
    <dbReference type="GeneID" id="71990781"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_10903"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.870:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="481"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="798"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="798"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UJO21253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="955" mass="105901" checksum="68A0150830BF37E0" modified="2023-09-13" version="1">MSSLVDAMMRSEELGPQEPRSDGTRGGRRQARSSSRPRGPPSVSTPGMHSDIEGFADDEVVGRRGNRPRLPGGQDVPRVVDTTAETLGIQFERFLENFTEDPTASAAPASSAVTTNKYYIAQIHGLCQFKLSTLYVDFTHLMDHERGILANAIQGDFYRFQPYMLRALNNLIAKYEPQYYREHRQPGSTTARTDTSLATQSLSEEDNLGDKTPNQQTDKIFTIAFYNLSLVSRVRQLRTEHIGHLVSISGTVTRTSEVRPELHLATFICEVCTSVVPDVEQIFKYSEPTQCPNATCGNRQGWRLDIRQSTFIDWQKVRIQENSSEIPTGSMPRTMDVILRGEMVDRAKAGEKCIFTGTLIVVPDVSQFKVPGTRVTAMRDSQAPRGGDVGGSGVGGLKALGVRDLTYRMAFLANMVTPDASTQGQTANQSLKGQAGNILSSLGQTVEIGGTTGEQAQQDYLDTLTPAEIDDLRQMVQQNNIFMRLVDSLAPMVYGHTVVKKGLLLQLMGGVSKVTPEGMALRGDINICIVGDPSTSKSQFLKYICSFIPRAVYTSGKASSAAGLTAAVVKDEETGEFTIEAGALMLADNGICAIDEFDKMDIADQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPVGGRYNRKTTLRANINMSAPIMSRFDLFFVVLDECNEQVDEHLAKHIVGIHQLKDEAIEPEYSTEQLQRYIRFARLFQPVFTEEAKTYLVQKYKELRSDDAQGGIGRNSYRITVRQLESLIRLSEAIAKANCVDEVSPNFVDEAFKLLQQSIISVEKDDVEFEEEDENAAEAGAEDEPQDDEQMDTNEEGAGSVRASQTPAPAPRPRTQIKFDEFMKIRNMLLRRVNDDQNTVEDGVEEDDLLVWYLEQIEDSLESQEQLETQRSLARKVLRRMVKDNVLMQIRGEGLADEQGEGLEQDDKVMYVVHPNCAVDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PFR7</accession>
    <name>A0A9Q8PFR7_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Non-heme chloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_08985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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        </source>
    </evidence>
    <sequence length="1223" mass="135956" checksum="2B63E6EBC6C0E9A0" modified="2023-09-13" version="1">MPRRQFVADLDKAKTDVLPVGISDVKAGEDDGQIEFLFTGGPNGLPFGAVKITALVPELSEYPKSHEYMIFAGDDTPPQISNALENVRGTNRKTVFELLDIISATLTRLSPDKDGDSQMPDSQFEEEQYEDEDDDDVYDSDHEAFEDSIPAHNPAYATQAPTATTKSGTSTRQFRQRIRSDLRTAKAAGFKVGVLGHLMEAQNSYVTVSIRISKLGVSEEAMQAWQVEPSDYLILIIQYPNGYKTNEELQGYDSLRLVPNLGMRVVAGRRYKPTLQEAIKAFTVVRKDERMSIGGTSLPPPDAVDAEESSIRDTFISKPLVNLMQERLVSLLRYRSAGLDWLGAEGFYQEQINTTANGGVNADIIPDRLYQKEVLYAALPDIVKADHYQSRGTTQYSFPLLAMQFLVRHFVRCTEFCLVCHRKLQTDVEAIKPYVCENPLCLYQYMSLGFGPSIEHEVLAQPYVCDLLISLCYNSAATRKLKDFPDGLSIVVPPVDSSKYNVIDEYSYGYRGRGNTGTPTPQKKSSVAATKAVYEVGFDRNRREIIFWDQTIGCPVKRGSWIVLNSDGLDGTDLHCRVAETTFWPTITIDEPVSVRQQLGGGTTPQTPAATRPVSPATTAPQWASARFQVYEEDFADLEKDGKCMAICRLLETLPNVLEMRDYLSKRHPAELKHWVERVSSSALTVLRWIIASNRSHILQVDGDAKFDRDGKPLPKHASSVFTKEQERCYGMKDYMQFRFAMGAPDKEQRFITEVRNTTSRLNLQYPTLFAWHGSPLYNWHMIIREGLHYKNVDHGRAYGDGVYHAKDSSTSGGYSGMGARGGYGHGTWPNSVLRISSAIALNEIVNAPSEFTSNNPFYVVKQLEWIQTRYLFVQCAPTSEHISIGVEKKPQNAHPQDPLRTIRGASDVIAIPASAIKSGKTARGVRAGDGDSPKDQPQNKKAKLLFGSAANDPIVLDDDDDDTVSVATDVADLEILFDEPPEPIVAPPSKNQKSAAEKIADQGPKTDFVPGSLNFSKLPLMPLPEYASTATTKRLMKELQSLRKVQDATPLAELGWYIDVDKIENVYQWIVELHSFHTFEGKGKPLPLADDMKKQRVKSVVLEIRFNKDFPFTPPYVRVIRPRFLSLGQGGGGHIVLGGAMCMELLTNTGWSSVSSMESVLMQIRMAIASEPYARLSPANGQGDYGIGEAADGYVRACHTHGWQVPPGFKEMAYGHGSNGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PHY1</accession>
    <name>A0A9Q8PHY1_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cercosporin MFS transporter CTB4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cercosporin toxin biosynthesis cluster protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CLAFUR5_12133</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin. The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules. These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids. Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767096.1">
        <property type="nucleotide sequence ID" value="XM_047911281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PHY1"/>
    <dbReference type="GeneID" id="71992011"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12133"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="104"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UJO22730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="598" mass="66101" checksum="1BD14CF640DA32C7" modified="2023-09-13" version="1">MVRRDTIESYIGDDWDEDGDDHSSLSLFHAGYSSYDSGWAREYEPTIVPVPARKPLPKPKVPSRAPTLLVPNNGEAPQDSNLVTWDKDDPANPHNWPSHRRWTSTVLIAMFAFIAPMASTMVAPALDTIADDYGIESQIEKFLVMSIFLLAFAVGPFLWGPLSEVFGRIRVMQGANLIFLIFNTACGFAKTKQQMMAFRFLSGIGGSAPQAIGGGILSDCFRAGERGLATAIYSLMPFLSPATAPIMGGYLTQNASWRWVFWITSIFDLAVQLACFLLLRETHHPTILKNKAKAFRRATGNPNLHTKWQGPDHSMREDLDEGAPMALFRGYQYGLMYLVFATFPMVFEEAYDMDVGPASLNYLSLGVGFIVGLQISGLMQDKVYTYCKEHEVDPSSLRNTFQAWKAYRHGAAKTDKGSLLPMSNSTPPPPFVVARKPLPGRSPTIKSIKRRGTGKSMKDPTKGLPEYRLPLVLPFSLLIPIGIFIYGWTAHYKVHWVAPNIGAAILAMGLIVCFNCAQGYVVDTYTTYAASATGAAAFVRTMCGFSFPLFAPAMYDHFGIGWGNSLLGFIALSLGMVAPVLLWRYGMWLRSNSTYCTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PI63</accession>
    <name>A0A9Q8PI63_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin domain-containing protein DSK2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CLAFUR5_11834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO22920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767286.1">
        <property type="nucleotide sequence ID" value="XM_047910982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PI63"/>
    <dbReference type="GeneID" id="71991712"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11834"/>
    <dbReference type="OMA" id="PGMDMFG"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14324">
        <property type="entry name" value="UBA_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16106">
        <property type="entry name" value="Ubl_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000024">
        <property type="entry name" value="Ubiquitin domain-containing protein DSK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="15"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="406"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UJO22920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="450" mass="46260" checksum="153F4DABFCBF2A83" modified="2023-09-13" version="1">MADSNTDGDAAEQQITFNIKSSSDAKHVVTVPLSMTVGDLKQKISTPEYADTPPERQRLIYSGRVLKDADTIASCKIKDGNTVHLVKSAASNQRQNPASQGGAVVPPGAGQPASNVPSNIAAGTGTGNPLAQLTGARYAGFHGLPGADMFGADGGMGAPPNPDQMLRMLDDPNFAQQMNEAMNNPAVLDMLRNNPMIRDNPMARAAIENPEMRRMMLNPDMIRMQMNMQRAMGQGGGEGVGAFPMPGQTDTTPATPGGNNESTTGTNSSATNAPSNPFAAFGQAGSGGAANPFAALFPGAGGNANQAGGAQGAGDAPGAGAAGQQNPFGNPFGGQGQDGPNNPFQQAAQQMMQNPEMMQNMMRMMGGGMGGNAGGEGAGAGGFNPFGAMGGFGAPTEPQAPADTRPPEERYESQLQSLNDMGFYDFDRNVQALRRSGGSVQGAVEYLLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIQ4</accession>
    <name>A0A9Q8PIQ4_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein RAD50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CLAFUR5_11902</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767486.1">
        <property type="nucleotide sequence ID" value="XM_047911050.1"/>
    </dbReference>
    <dbReference type="GeneID" id="71991780"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11902"/>
    <dbReference type="OMA" id="FSDYYYR"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000947">
        <property type="entry name" value="DNA repair protein RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001195">
        <property type="entry name" value="DNA repair protein rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="17">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="954"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1045"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="205"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="299"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="394"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="609"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="750"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="828"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="967"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1050"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UJO23120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1305" mass="148124" checksum="1EE94DC115B9A7FE" modified="2023-09-13" version="1">MSKIDKLQIRGIRSFDARNPMSIQFHAPLTLIVGTNGSGKTTIIECLKYVTTGELPPNAAKGASFVHDPSMAGEKEVLAQVKVSFTSTGGARMVCTRNLQLTVKKATRTVKTLEGSIKMVKDGEKNTMSSRVTEMNTLMPRSLGVSKAILENVIFCHQEDSLWPLAAPKDLKEKFDQIFEALKYTKAIENIKILQKNQRVELGKLEIEEKSAAKDQERARELKANRQKLTVRAQQLETQRDDFGRQMQEASRQATEIWKKVGDAEKIVGELNGKRIARDTKQESVESLQSTMEMLTGTDAELQAMLDQHEERIEMYKTELAEEKADYQALAAELKEARVQASAKEREAGSYEAQKQNFDHQVENRKRLVQETARSHDIRGYDYELDDAQVKAFMEQISRKARDQQAEFERARTEAQEKLKQQQSVLTGINEKSSAKRQSKETAKTTIATYDRKVRTLQAEQNKLSLDEGGKTTLESQLKSLQDQLSNAKGEMNSSDWNAIIETAEAELRRLEDRKDKLDAECAEAARRAGDSAQLDYVQKELNDRQRSLDSMQKSNGNRIAKVLGDNWRASSLDQDYERALTHSTAEVAEAERQRNGTEQGQHFIASRLRERNDALKAAEREQKSAEQTIEKALGCRPERYREELSGLEEERDALKSGKDGFEALSSYLRSCIKTAESHNFCKTCMREFGSKDKKGEHQRMKAEVEKYLEKHRPKEDADVSLDDTEGILQTAKAAGPAYEAWEKLKHKSIPDLRSEISKLETERDQLTARLEQQDNAVELKKSAKADIDALARTVQNMVKYVADISSFESQIKELTAKQKEAGLSRGLEAVQIDIKKANEEAKAAKARHSEATNSRDRTKTRISSLELQISDAKGKLRDAKYQLQQKKSLQAQEDEYRSLIVEQRKHITTLDAELQDLATELSTEKAKYDEITRRRGDQDRNLQDKANKLNKSVSELKSADGAIQAYHDKGGDEQLRRSRREVESTKKEVTRIEESQMQAVSRIKQLETRTRDDEGTKTSIINNQRYRKDLKALDTVRSEISELEQTNAEADKKKYEQQVESHQRRRNEAASKQASVTGQLTSINDQLEQIEKDWRTTYANAGREFRKAHIKVETTKAAIEDLGRYAGALDKAIMKYHSLKMDAINAIIGDLWRRTYQGTDVDTILIRSESETVKANKSYNYRVCMMKQDVEMDMRGRCSAGQKVLASIIIRLALADCFGVNCGMIALDEPTTNLDQENIEALARSLADIIQVRRTQSNFQLIVITHDETFLKAMSSSEYTDDYFRVSRGPEQESCIDKQSIANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIR9</accession>
    <name>A0A9Q8PIR9_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_11783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090172">
        <property type="protein sequence ID" value="UJO23150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767516.1">
        <property type="nucleotide sequence ID" value="XM_047910931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIR9"/>
    <dbReference type="GeneID" id="71991661"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_11783"/>
    <dbReference type="OMA" id="KSYPTHP"/>
    <dbReference type="OrthoDB" id="3650981at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040162579" evidence="2">
        <location>
            <begin position="17"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="573" mass="61398" checksum="7791B6FE15D66CB9" modified="2023-09-13" version="1">MLSKITLLALLGTAYAVPGEQPEGYGNGYGDEGQPHAYHEPPSYGPPSYKPAPSHKPAPSYKPEPSRKPAPSYKPEPSHKPAPSYKPSYAPHPPASHPTASWSYAPHPSYALPPYVPKPKPSGSYAPPPYVPKPSQPGSYASQPTTKTVNKSYKTTVTSETVITLTKPSSPASMPQQSKPSSPASMPQQSMPKQSTPGSPPMPTAPAVCPPAAPAVTYTETKYETKTETVHYSQVCPACSTSTIYYSAQTPVSYCPTYGSMVPPPQSSAPVPPEPTQPGTPPVAPLPPKAPSSSAPPSPPKAPSSYTTPGSPGKPTVPVQQPSVPVQQPSKPMTHPQPPVTVSKPTPSQPMTYPHPAPPVSMPTTYPKPPVHQQSKPATSYPSHPASYPSHPVQSYPSHPPKSYPSHPSQPSQPPKSYPTHPKSYGPPPQSYPTQSKSYEHPPKSYPTHPKSYGPPPQSYPTQSKSYEHPPKSYPTHPKSYGPPPQSYPTHSKSYGPPPPAYTHPVYSQPPPEYHTPKPYTTTTTTTTENKPYHPAPSYPPHAPAYSAPPPTYEQPPSYEQPKPYAAPPAQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PIX3</accession>
    <name>A0A9Q8PIX3_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Smad nuclear-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CLAFUR5_12675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047767691.1">
        <property type="nucleotide sequence ID" value="XM_047911823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PIX3"/>
    <dbReference type="GeneID" id="71992553"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12675"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="216"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UJO23325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="311" mass="36366" checksum="0B22046EC3BC0F1A" modified="2023-09-13" version="1">MDSRERRYSREDDSSDAGRRDRKFGGSSRDSDRRREGRHDRSPTDRERSHRHRDPDREEEGRSRRKGYIRRDRDRSADEASDGVRESKRDRRRRSRSRSRDRRERRRSRSPPAKKRRSRSRSPMKRSKGPLPSQDESFRGEVAPGEAPPPEKQKPNFKPTGLLAKEANTVAGTNTVLKYHEPPEARKPPTKEAWRMYVFKGKDLVDTIYLHQKSAWLIGRDEKVTDLHLEHPTISKQHAVIQFRHRTTTNEYGDKSNKVKPYLIDLDSTKGTTLNGKKLEGSRYMELLDQDVVTFGGSEREYVMMLPSAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJR0</accession>
    <name>A0A9Q8PJR0_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CLAFUR5_12930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768056.1">
        <property type="nucleotide sequence ID" value="XM_047912078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJR0"/>
    <dbReference type="GeneID" id="71992808"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12930"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="UJO23690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="75" mass="8207" checksum="DBCD126FBD0B50B0" modified="2023-09-13" version="1">MRTEMAAGVGFDKFWHEGGAVTPDESAKSLREWVETFDISKTGTHWASRGPGDIGTAEHVLGPKDKLATPLQLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PJX9</accession>
    <name>A0A9Q8PJX9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CLAFUR5_12819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090173">
        <property type="protein sequence ID" value="UJO23792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_047768158.1">
        <property type="nucleotide sequence ID" value="XM_047911967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9Q8PJX9"/>
    <dbReference type="GeneID" id="71992697"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_12819"/>
    <dbReference type="OMA" id="ITQGYIP"/>
    <dbReference type="OrthoDB" id="205099at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26204">
        <property type="entry name" value="Med14_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="11">
        <location>
            <begin position="104"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1046"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1058"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UJO23792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="1117" mass="122090" checksum="D69E03BC1B76A805" modified="2023-09-13" version="1">MPGRLIMDQQGAIGSQDLKKDRSQAQIASLPKKPDFAQHTPAPQVNGPMTPAVNGSIPNGTSTHNAPSTVTNGSGMAADTAMSGMEAPPELDQSWQENREVWKSMGKMIERTAQACYSDLLDTVNRLHETPLVVPAAQPNGAAPQVNDTSQDSINKKRIIMDFAKGQRDRFMKSAVLVAWAKTTGDAMSTLIDVRYAQSKEQNAQDTAIWRIGDSKKATEIVKQRSPNIQGALDLLATGKASHLPGLNFVQPKRMSAKQLLKTLQGMNVTLATRLNLHEDLPVHFNDFRIANGRATFRVPGEFEVDLSVADEEPTSQFYLIDIRFLFVPAPIGLHEALRAQLELRANAELSAKGLQGCYDFLHNFVLTHKINVLKSQVAKLAQEKWFDCLSVQTHRRVITLQYWTAVPGRKSWLEIGVATGKDAARRFRRTPNPQLSIRWFRRGEEMKDTKLDIDWLNLDVEQILSEVVARHISWSLTSIKDRLQALAGPESKLDMHLDTSESVPEDCSLRLSIAGLQDAVVVRQEPVTGKLSVSPPNQRATRCELAINSNEQVDTATVLASALCDMMKDRVDVVASIAGWSQLREEFAKDSLKQAFGNASIRAYMCSGGWGKQWALFATFSLVGEKWWVVRLADKPSADRPGNTRAIAETRAIPTQDRPFGQTALSRTALLQIEQAAAAEVSCAVLTQQLAMAGIRHKTDGLAPISLHEASATLDDSIRESSVFLANCTFLKHTSGKHSTITSLRVTHNGLMANMPTADEEPAMARYDLRLTVDQGQLKYLREYLTTKGRNADVAMNASGALALRLRTPFGAPYLDQIYARLKACQRLNSFIANINASKFRATNVSLSRLSFVYNESPELTATILLANDSGSPATLALEPKASNPQFRARIVFEKLLNMIIDKGTSFAALCQTLQISLPVLHTLDKLETAHLSPKDTFIHIRHPTLYTIEYRAPLPALNINILMQDRRTSNGLVRAWSISTSLPKDGISASAVGKALVELSKFQGDSWHGLGDGSFVALLKGAAKAIEQIDQTVRSSANAATTATTNATRQGEASHAAPKPQAPAQQKSLPNTGSTSAKTATSAKGGAKGNVPTTNGRPAPKPNVTRVKNEIIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKL9</accession>
    <name>A0A9Q8PKL9_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="79"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="468" mass="53662" checksum="A5D94238C9B9F212" modified="2023-09-13" version="1">MATQAASEVDGGPQVFRHTPFDDAQTHVRLLRFVSKHEDDVRLEISTWTRPELPKDEGEDEHEWRLWHDRRRPYETLTFHAISYTWGDEKDQRQIKINGLAFTVRRNCFEAMAKVRLHYPDEYFWIDSICINQGDDVEKSAQVAMIYETFCGAERVLACLGDLCMVRDTTGMKNHYKSSDPEGPAIFAHDRDGPTLDSNTLADTPSHAAHTLESRIREALPHGDISLSHLSRNEKLHPICQPWVDSLTFSTAQSLRHGLWSFLVQEYWSRVWIMPEIAAAGDDLQLLVGTAKVNSLHIHLLMMLAGGRGGSDKHHINFNKLDVSRIWGEHKPPRLHDEYISDGCRVAMGTIARKQTESLSDSLLGSRGKRCSDPRDRIYALLPIMHSHVPFRPDYSKSCFKLAVEAFGYVRVHEAHEGEFFTIIALALEVDEDDLARALGLDGTLNDEIERFRKESRERRVKERREKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PKN4</accession>
    <name>A0A9Q8PKN4_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CLAFUR5_13832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Race5_Kim</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912980.1"/>
    </dbReference>
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        <property type="component" value="Chromosome 12"/>
    </dbReference>
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        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UJO24139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <sequence length="287" mass="31902" checksum="0170A599FC9C8CFD" modified="2023-09-13" version="1">MAPYTGGTIVVVPSCIGMIMLGDSIYGSVTGSKNVYLRFKVILQGGRIPILTVTVDFGNKFRSADIPLNRCTDIAIDFGRVRVNDWTDLNPKLEGWAEHGVTFKQQFLTGRIRGLPSKIEWSGASIEELGQNGKELIRLFEQDHKDISVLLVWDGRAETPSLEKFRKACEAGIEERLREDLEADNEATKEEDERDVLPKCDGKKRSAGSSLGESSEYQVVAKKPKAAGAKYEAAREARYEDLEINGLTSGAALKDLSDEKLDAMTFQLIEMLTGYSRERKKCQAEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PL04</accession>
    <name>A0A9Q8PL04_PASFU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
                <person name="Zaccaron A.Z."/>
                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_047912699.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="71993429"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13551"/>
    <dbReference type="OMA" id="AAYQMSQ"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF26">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_4G05870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UJO24456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000756132"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32731" checksum="632815C663CE73E2" modified="2023-09-13" version="1">MSSDKKQFESGFQPDVQHQKVPGLQSDMTPAPSTEYVPTPEGGYKLYQAAGKLKDKKALITGGDSGIGRATAVLFAMEGADSFIAYLPEEEKDAQETKKLVEKYGRKCYLHATDLKDKKNCKKVQEEALEKMGAINILFNNHAYQMMTNNIHDLTEEQWEHTFNTNIHPFFYLSKYVLPHMNQGDTIINNASINAYIGRPDLLDYTSTKGAIVAFTRGLSNQFVHKGIRVNAVAPGPVWTPLIPATMNDEAIKQFTSPMGRPGQPSEIATCVVFLASTDSSQLSGQTIHANGGAIVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9Q8PLD1</accession>
    <name>A0A9Q8PLD1_PASFU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patulin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CLAFUR5_13959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Passalora fulva</name>
        <name type="common">Tomato leaf mold</name>
        <name type="synonym">Cladosporium fulvum</name>
        <dbReference type="NCBI Taxonomy" id="5499"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Dothideomycetidae</taxon>
            <taxon>Mycosphaerellales</taxon>
            <taxon>Mycosphaerellaceae</taxon>
            <taxon>Fulvia</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zaccaron A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="journal article" date="2022" name="Microb. Genom." volume="8" first="e000819" last="e000819">
            <title>A chromosome-scale genome assembly of the tomato pathogen Cladosporium fulvum reveals a compartmentalized genome architecture and the presence of a dispensable chromosome.</title>
            <authorList>
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                <person name="Chen L.H."/>
                <person name="Samaras A."/>
                <person name="Stergiopoulos I."/>
            </authorList>
            <dbReference type="PubMed" id="35471194"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Race5_Kim</strain>
        </source>
    </reference>
    <comment type="similarity">
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    <dbReference type="EMBL" id="CP090174">
        <property type="protein sequence ID" value="UJO24560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_047913107.1"/>
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    <dbReference type="AlphaFoldDB" id="A0A9Q8PLD1"/>
    <dbReference type="GeneID" id="71993837"/>
    <dbReference type="KEGG" id="ffu:CLAFUR5_13959"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000756132">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="I
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